Errors that occur in the prescribing phase of the medication use process are less likely to reach the patient and cause harm because of the opportunity to intercept the error in the phases of transcribing, dispensing, administering, and monitoring. However, some prescribing errors make their way through the entire medication use process, reach the patient, and cause harm. A query of the Pennsylvania Patient Safety Reporting System (PA-PSRS) database revealed 811 Serious Events (harm score E through I) associated with reported prescribing errors that occurred from July 2004 through June 2016. Nearly 5% (4.7%, n = 38) of these errors required intervention to sustain life or contributed to or resulted in the patient's death. The most common types of events reported were wrong dose/overdosage (32.2%, n = 261), monitoring error/documented allergy (14.5%, n = 118), dose omission (14.3%, n = 116), and wrong patient (4.4%, n = 36). Recommended system-based risk reduction strategies include optimizing computerized prescriber order entry with clinical decision support to facilitate screening for drug-related problems; and developing well-designed standard order sets.
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