An analysis of reported adverse drug reactions
- Collection:
- Health Policy and Services Research
- Series Title(s):
- Pennsylvania patient safety advisory
- Author(s):
- O'Connor, Michael, author Grissinger, Matthew, author
- Contributor(s):
- Pennsylvania. Patient Safety Authority, issuing body. ECRI (Organization), issuing body. Institute for Safe Medication Practices, issuing body.
- Publication:
- [Harrisburg, Pa.] : Pennsylvania Patient Safety Authority, [2014]
- Language(s):
- English
- Format:
- Text
- Subject(s):
- Drug-Related Side Effects and Adverse Reactions -- epidemiology Drug-Related Side Effects and Adverse Reactions -- prevention & control Contrast Media -- adverse effects Drug Therapy Medication Therapy Management Prescription Drugs -- adverse effects Risk Factors Risk Management Humans Pennsylvania United States
- Genre(s):
- Technical Report
- Abstract:
- Past research has shown that both the incidence and severity of adverse drug reactions (ADRs) are significant. The American Society of Health-System Pharmacists (ASHP) has published guidelines on ADR monitoring and reporting. As a part of these guidelines for pharmacists, ASHP states that any ADR program should include "evaluating, documenting, and reporting ADRs as well as intervening and providing educational feedback to prescribers, other health care professionals, and patients." Over a 12-month period, Pennsylvania hospitals reported 4,875 reports through the Pennsylvania Patient Safety Authority's Pennsylvania Patient Safety Reporting System describing ADRs. Nearly 30% (n = 1,365) of these reports described ADRs to contrast agents, which are considered high-alert medications by the Institute for Safe Medication Practices. Other high-alert agents that were frequently reported include opioids, taxane derivatives, platinum analogs, warfarin, and insulin. While many of the ADRs reported to the Authority could not have been prevented, there are strategies that can be utilized to reduce the incidence and severity for a portion of these ADRs. These strategies may include appropriate premedication regimens, providing clear instructions for the administration of medications with complicated infusion rate titrations, ensuring thorough patient medication and allergy histories are completed, and improving the quality of ADR reports within healthcare organizations.
- Copyright:
- Reproduced with permission of the copyright holder. Further use of the material is subject to CC BY-NC-ND license. (More information)
- Extent:
- 1 online resource (1 PDF file (9 pages))
- Illustrations:
- Illustrations
- NLM Unique ID:
- 101634439 (See catalog record)
- Permanent Link:
- http://resource.nlm.nih.gov/101634439