At the behest of Walter W. Palmer, chairman of the Department of Medicine at Columbia University's College of Physicians and Surgeons in which Heidelberger served as chemist, Heidelberger in this letter summarized his more than three decades of research in chemotherapy, polysaccharide chemistry, and immunochemistry. Heidelberger had met Palmer in Donald D. Van Slyke's laboratory at the Rockefeller Institute during the early 1920s, and it was Palmer who offered Heidelberger a professorship as Chemist to the Medical Service of the Presbyterian Hospital, Columbia's teaching hospital, in 1928.
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