In this exchange of letters Heidelberger and Pappenheimer discussed hypotheses and evidence regarding the location of the sites at which antibody molecules (later shown to be Y-shaped) bind to antigens. One hypothesis, proposed by the preeminent physical chemist Linus Pauling and discussed in this letter, held that these binding sites were located at the ends of a symmetrical molecule.
Copyright:
The National Library of Medicine believes this item to be in the public domain. (More information)
