Effect of Pentaquine in Patients with Hypertension
- Contributor(s):
- Wilkins, Robert W. Proceedings of the Society for Experimental Biology and Medicine Freis, Edward D.
- Publication:
- Society for Experimental Biology and Medicine (New York, N.Y.), 1947
- Language(s):
- English
- Format:
- Text
- Subject(s):
- Hypertension Antihypertensive Agents Aminoquinolines
- Genre(s):
- Archival Materials Articles
- Abstract:
- Following World War II, Freis returned to Boston to work with Wilkins at Massachusetts Memorial Hospital. Their work on pentaquine was an outgrowth of anti-malarial work conducted by others during the war, in which it was observed that some volunteers developed orthostatic hypotension. In this article, they report that the drug did lower blood pressure, yet it would not be an effective antihypertensive agent because it also produced severe toxic effects.
- Copyright:
- This item may be under copyright protection; contact the copyright owner for permission before re-use.
- Extent:
- 4 pages
- NLM Unique ID:
- 101584929X68 (See in Profiles in Science)
- Profiles in Science ID:
- XFBBFH
- Permanent Link:
- http://resource.nlm.nih.gov/101584929X68
- Archival Collection:
- The Edward D. Freis Papers (Profiles in Science)