In this article, Jones and Nirenberg provide a progress report on code translation efforts. They find that almost every amino acid tested can be coded by a polymer containing only two bases. The article includes approximations of nineteen triplet codewords and suggests that any theory concerning the physical basis of the code must explain the available data revealing the high coding efficiency of polynucleotides, marked codeword specificity, and degenerate codewords. The degeneracy model of Gamov and Watson-Crick pairing are among some of the ideas discussed.
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