Regulation of Acetylcholinesterase in Neuroblastoma Cells
- Contributor(s):
- Blume, Arthur J. Gilbert, F. Nirenberg, Marshall W. Wilson, S. Farber, John L. Proceedings of the National Academy of Sciences of the United States of America Rosenberg, Roger N.
- Publication:
- National Academy Press (U.S.), October 1970
- Language(s):
- English
- Format:
- Text
- Subject(s):
- Neuroblastoma Cell Transformation, Neoplastic Enzyme Activation Acetylcholinesterase
- Genre(s):
- Archival Materials Articles
- Abstract:
- This article is one of the first published reports of Marshall Nirenberg's work during his transitional move toward neurobiological investigation. Experimental findings in the article show that when tumor cells shift from the dividing to the non-dividing state, they are influenced by the expression of a set of genetic characteristics required for neuron differentiation. As progeny cells remained committed to a program of neuron differentiation, the authors anticipated implications for the study of healthy neurons--the "possibility" that "normal sympathetic neuroblasts are also inversely committed to a pattern of neuronal differentiation."
- Copyright:
- This item may be under copyright protection; contact the copyright owner for permission before re-use.
- Extent:
- 7 pages
- NLM Unique ID:
- 101584910X208 (See in Profiles in Science)
- Profiles in Science ID:
- JJBBMY
- Permanent Link:
- http://resource.nlm.nih.gov/101584910X208
- Archival Collection:
- The Marshall W. Nirenberg Papers (Profiles in Science)