Third in a series of letters McClintock rushed off to Rhoades in March of 1950. In them, McClintock developed a broadbased theory of the genetic control of development. The letters represent McClintock's extremely excited state: they are difficult to follow and included many addenda, amendments, and margin notes. Her thinking on this matter resulted in an article later that year in the "Proceedings of the National Academy of Sciences" that further marked her preoccupation with the fundamental theoretical and philosophical problems of genetics.
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