During her 1954 visit to the United States, Franklin met or renewed acquaintance with many virus researchers, who were able to send samples of their virus material and brainstorm with her on her x-ray diffraction findings. Heinz Fraenkel-Conrat at the UC Berkeley Virus Laboratory was especially helpful, sending a variety of heavy-atom substituted TMV preparations. In this letter Franklin reported on her latest work with mercury-substituted TMV, which indicated a very different number of protein sub-units than previously believed.
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