The Application of the Freezing-Drying Technique to Retinal Histochemistry
Contributor(s):
Lowry, Oliver H.
Hastings, Albert Baird, 1895-1987
Anfinsen, Christian B. (Christian Boehmer), 1916-1995
Journal of Cellular and Comparative Physiology
In this article, Anfinsen, Lowry, and Hastings presented a method that permitted histological examination and quantitative enzymatic study of individual freeze-dried sections of tissue in order to study enzymatic localization in the various layers of the retina. Published shortly before Anfinsen received his Ph.D. from Harvard in 1943, this is a quantitative, histochemical study of the retina in which the three researchers adapted an earlier technique for the identification of chemical components in cells and tissues that was developed by Kaj Linderstrom-Lang and K.R. Morgan.
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