- Observations on the comparative state of medicine in France, England, and Germany: during a journey into these countries in the year 18351
- Observations on the curability of consumption: by a new, safe and painless mode of treatment, illustrated in selections from three hundred and ten late cases1
- Observations on the cure of strabismus: with engravings1
- Observations on the customary use of distilled spirituous liquors: particularly addressed to the inhabitants of Pennsylvania, of all denominations, and also to the people of the United States generally1
- Observations on the disease called the plague, on the dysentery, the ophthalmy of Egypt, and on the means of prevention: with some remarks on the yellow fever of Cadiz, and the description and plan of an hospital for the reception of patients affected with epidemic and contagious diseases1
- Observations on the disease of gonorrhoea: submitted, as an inaugural thesis, to the examination of the Reverend John Andrews ..., the Trustees and medical professors of the University of Pennsylvania, on the 8th day of June, 1803, for the degree of Doctor of Medicine1
- Observations on the diseases incident to pregnancy and childbed1
- Observations on the diseases of the army2
- Observations on the distinguishing symptoms of three different species of pulmonary consumption, the catarrhal, the apostematous, and the tuberculous: with some remarks on the remedies and regimen best fitted for the prevention, removal, or alleviation of each species : to which is added, an appendix on the preparation and use of lactucarium, or lettuce-opium1
- Observations on the education of the deaf and dumb1
- Observations on the efficacy of white mustard seed in affections of the liver, internal organs, and nervous system: and on the general management of health and life1
- Observations on the epidemic now prevailing in the city of New-York, called the Asiatic or spasmodic cholera: with advice to the planters of the south, for the medical treatment of their slaves1
- Observations on the epidemic of 1819, as it prevailed in a part of the city of Baltimore: comprising an accurate history of its origin, progress and effects, as far as they can be ascertained : to which are affixed, by way of appendix, some remarks on the medical treatment of the disease, as found successful in the hands of the most distinguished members of the profession1
- Observations on the epidemic yellow fever of Natchez, and of the South-west1
- Observations on the epidemical diseases of Minorca: from the year 1744 to 1749 : to which is prefixed a short account of the climate, productions, inhabitants, and endemial distempers of Minorca2
- Observations on the establishment of the College of Physicians and Surgeons in the City of New-York, and the late proceedings of the regents of the university, relative to that institution: communicated in a letter to James S. Stringham, M.D. professor of chemistry in Columbia College1
- Observations on the growth of the mind: with remarks on some other subjects1
- Observations on the hepatic state of fever1
- Observations on the influence of religion upon the health and physical welfare of mankind1
- Observations on the instruction of blind persons, in a letter to Roberts Vaux, John Vaughan, and Robert Walsh, esquires1