In the care and management of the critically ill patient. It is important to have available at the patient's bedside. Certain diagnostic information about his cardiovascular system over the past several years, since the early 19 sixties, this has been accomplished primarily through the use of central venus pressure catheters. However, it has been shown that the central venus catheter and central venus pressure reflect principally volume states. And this method has had its greatest application in hypovolemic shot and volume depletion states. It has also been shown that it does not correlate well with left ventricular performance and left ventricular hemodynamics. For example, in the patient with cardiogenic shock, the primary problem is due to decreased contractility of the left ventricle which has been damaged by the heart attack. This is reflected by an increase in the left ventricular and diastolic pressure or the so called filling pressure of the left ventricle. And this in turn is transmitted to the left atrium. The left atrial pressure is then transmitted to the pulmonary circulation where if this becomes sufficiently high fluid is forced across capillary basement membranes. And pulmonary edema develops prior to that the pulmonary artery pressure and most importantly, the pulmonary artery occluded pressure or so called pulmonary wedge pressure increases first, if the strain is sufficient, right heart failure develops and it is only at that point that the central venus pressure will become abnormally elevated. Therefore, it would be impossible if one were monitoring only central venus pressure to intervene at a sufficiently early point to reverse this path of physiologic process before the central venus pressure increased due to right heart failure. Therefore, it would be very important and very useful in the management of such patients. If it were possible to know the pulmonary artery pressure in such individuals, we can apply this information to the critically ill patient. In order to make decisions regarding volume expansion, the use of diuretics and the use of inotropic drugs or the use of various combinations of these. Since we know that the pulmonary artery eluded pressure is a reflection of and estimate of the left atrial pressure, which is an estimate of the left ventricular filling pressure. We can predict the sequence of events of the patients, cardiovascular events and make early therapeutic interventions if it were possible to know these values from the pulmonary artery pressure. In 1972 physicians, Swan and Gams developed and introduced a new type of cardiac catheter. This is a lightweight multiple lumen catheter which has at its end, a small inflatable balloon. This catheter can be passed at the vet side and is positioned in the pulmonary artery by inflating the balloon. The catheter is wedged by eluding a small branch of the pulmonary artery and thereby records a pulmonary capillary wedge pressure, which is a measure of the left atrial or left ventricular and diastolic pressure. The balloon at the tip of the catheter is then deflated and the catheter then springs back into the main pulmonary artery with the catheter in the proper position. Serial determinations can then be made of pulmonary artery pressure, pulmonary artery oxygen saturation and content and serial cardiac output determinations made by the thermodilution method. The purpose of this film is to review the rationale and use of the technique of pulmonary artery pressure monitoring and to demonstrate the technique of insertion and the application of this method to the critically ill patient. This diagrammatic graphic of the human torso shows the entry site of the catheter from the right medium basilic vein. Other sites may be used. For example, the femoral vein, the subclavian or the external jaguar system. The nurse takes the patient's blood pressure at the bedside and the patient's right arm in this instance, has been draped in, prepped in usual standard sterile fashion and the skin has been infiltrated with either one or 2% lidocaine. This is the pulmonary artery catheter and this particular one is a seven fringe. The catheter is filled with Heiny saline and the balloon on the tip of the catheter is an inflated and check for any leaks in this instance, we are infighting with air. However, if a right to left shunt is suspected, one should use carbon dioxide. A small incision is then made over the medium basilic vein in the Annabi FASA and the medium basilic vein is isolated prior to this time, a transducer has been calibrated and zeroed and has been placed at the mid thorax level of the patient. So that accurate pressure recordings may be obtained. This transducer converts the hydraulic fluid waveform to an electrical signal which is then displayed on the oscilloscope, which is at the patient's bedside. The area is kept cleansed and sterile. And the patient is observed under continuous electrocardiographic monitoring with periodic blood pressure determinations. The distal portion of the vein is then ligated to prevent any oozing. A small incision is then made in the vein. And in this instance, we are using a number 11 blade, a silk suture has been placed approximately and this will be used to secure the catheter in place to be honest. The outside of the catheter is marked with black markings and each mark represents 10 centimeters. Therefore, it is possible to tell precisely how far the catheter has been advanced inside the body. From previous measurements, we know that once the catheter has been inserted approximately 40 centimeters, the tip of the catheter then lies within the thorax. Yeah. This graphic diagram shows the positions of the catheter in the heart. The catheter enters the heart from the superior vena cava and enters the right atrium. It then crosses the tricuspid valve and enters the right ventricle and then is advanced across the pulmonic valve by the flow of blood into the main pulmonary artery. It is then advanced to a branch of the pulmonary artery and produces a pulmonary wedge or occluded pulmonary artery pressure. The catheter is an advanced from the medium basilic vein. In this instance to the heart, the catheter has advanced to the intrathoracic position and the balloon is inflated. Commonly, this procedure is done at the bedside without benefit of fluoroscopy or X ray. However, in this instance, we are utilizing X ray cinematography to demonstrate the actual appearance and course of the catheter in the body and in the heart, it is then carried to the right atrium where a characteristic waveform is produced, which has typical A and B waves in the phasic pressure curve. Both phasic and mean values are recorded and the normal right of pressure is 2 to 5 millimeters of mercury with a mean of approximately 2 to 3 millimeters of mercury. The catheter is then slowly advanced to the right ventricle where a characteristic ventricular pressure curve is recorded in this waveform is usually 25 over zero millimeters of mercury as the catheter is advanced across the pulmonic valve to the pulmonary artery. Again, a characteristic waveform is produced and it should be noted that the diastolic pressure does not reach zero. This localizes the position of the tip of the catheter in the pulmonary artery. The normal pulmonary artery pressure is 25/12 to 15. The mean value is also important and is normally 16 to 18 millimeters of mercury. The catheter is advanced with the balloon inflated and produces a characteristic waveform which is very similar to that scene from the right atrium with characteristic A and B waves, but with a higher pressure reading. So the pulmonary capillary wedge pressure has previously described as a very accurate estimate of left atrial pressure, which is a very accurate estimate of the left ventricular and diastolic pressure, which normally is approximately 12 millimeters of mercury. The pulmonary artery wedge pressure and left atrial pressure are virtually identical except that the pulmonary artery wedge pressure is delayed in time. The balloon on the tip of the catheter is then deflated, allowing the tip of the catheter to spring back to the main pulmonary artery. This produces a very characteristic change in the wave form which can be seen on the monitor, changing from a capillary wedge pressure to a pulmonary artery pressure. Blood samples can be drawn from the pulmonary artery for determinations. As previously described. The catheter is then flushed and connected to the transducer. The catheter is then secured in place and the incision closed in standard surgical fashion. And in this instance, we have used 40 silk, the catheter is then left in the main pulmonary artery for subsequent measurements of pressure, cardiac output and oxygen saturation and other biochemical determinations. A sterile bandage is then placed over the incision and the cat that are secured, the catheter is then connected to the monitor and continuous monitoring of the pressure and electric cardiogram are then recorded. Yes. At the patient's bedside, frequent recordings and observations are made of the patient's electrocardiographic monitoring and the pressure wave form and these pressures are recorded. The intervals and limits are indicated by the physician. Yeah, it is important to notice the waveform on the pulmonary artery and pulmonary artery wed pressures. If the waveform completely disappears, it suggests that the tip of the catheter is occluded or against the wall of a vessel and requires repositioning if a persistently dampened pressure is recorded with the balloon deflated. It suggests that the catheter has migrated peripherally and requires repositioning. These are indications to notify the physician in charge with the pulmonary artery catheter. Now, in the proper position, it is possible to have available at the patient's bedside information about serial cardiac output by the thermal dilution method, pulmonary artery pressure and pulmonary artery of clued pressure. And next Venus, pulmonary artery oxygen saturation and content in this film. We have reviewed the rationale and theory of pulmonary artery catheterization and pressure monitoring and we have demonstrated its practical application in the care and management of the critically ill patient