CROUPOUS PNEUMONIA. A CONTRIBUTION ,7- TO THE h S’ /0 * \ CLINICAL HTSTOR^ OF Croupous Pneumonia. A report of Eleven Cates of Croupous Pneumonia occurring in private practice between the dates of Feb. .and June, 1878. By D. WEBSTER PRENTISS, A. M., M. D., Professor Mat. Medicaand Therapeutics, National Medical College, of Washington, D. C. (Read before the Med. Society of Dist. of Columbia, March 25, 1879.) Croupous pneumonia is an endemic disease belonging to the class of infectious diseases. It is only of comparatively recent date that the nature of this disease has been correctly understood, nor indeed is it even now admitted by all writers that the above proposition is true. To Austin Flint in this country, and Meinyer Jiirgensen and others in Europe, is due especial credit for pointing out with clearness the natural history of croupous or “lobar” pneumonia, and showing it to be a self limited disease, of constitutional character, in which the local inflammation in the lung is but a symptom of the general disturbance—-just as is the a flection of Peyer’s patches in typhoid fever, or the skin eruptions in the exanthemata. The onset of croupous pneumonia is almost always sudden, preceded by a chill, in which it corresponds with other zymotic diseases. The lung lesion frequently does not appear until the 2d or 3d day—and then bears no constant relationship to the severity of the fever. The fever is regular 2 in its course with morning decline and evening exacerbation. At the sudden crisis, about the 7th day, the pneumonic inflam- mation often continues unabated, as indicated by the physical signs and quickened respiration—but the fever utterly disap- pears—the pulse and temperature becoming normal, and the appetite returning. The disease is most prevalent in the presence of its exciting causes, chief of which is exposure to cold, wet weather; but we cannot believe, reasoning by analogy, that these conditions alone are suflicient to produce it. In the cases reported below, no connection whatever existed between them, nor with any other case as far as could be ascer- tained ; yetthere are instances occurring continually in the practice of physicians, that look suspiciously as though an element of contagion was present. Two or three years since I was called to a case of croupous pneumonia in a child—in a family of four children, all under the age of eight years. The parents were wealthy and the children hearty and robust— well cared for in a warm comfortable house, where they had the least possible exposure to cold. When the first child had been sick four or five days, the other three were all taken down at once with the same disease. All the cases ran the typical course to recovery. Again in the winter of 1876 and 1877,1 noted a case in a child 10 years of age, coming on without any unusual exposure to cold, and running the regular course to crisis on the 7th day and prompt recovery. Just at the time of the crisis a younger brother, aged 6 years, was attacked with the same sequence of symptoms and result. These latter two cases made the greater impression, that my interest in them was closer than a merely professional one, and I was watching them night and day. Such cases create the suspicion that the disease is contagious, though only to a faint degree, and indicate that the period of incubation is a short one—from 4 to 7 days. If it is contagious, analogy would sug- gest the sputa from the diseased lungs as the principal source of contagion, just as are the enteric discharges of typhoid fever and cholera. It would be inappropriate in an article of this description to 3 enter into a discussion of the diagnosis between croupous and catarrhal pneumonia, albeit the differences between the two pre- sent the strongest argument in favor of the zymotic character of the former. Catarrhal pneumonia presents a picture exactly the opposite of that given above, except only as to physical signs—the in- sidious approach, the irregular character of the fever, no defi- nite course, and especially the close sympathy between the lung disease and the general symptoms. Case I.—Croupous Pneumonia at Base of both Lungs in an Adult. Mrs. S., Irish, 48 years of age; stout, healthy woman, who has had no sickness for many years. February 28th, 1878.—Chill in evening, followed by fever and cough, after prolonged exposure to cold. March 2d.—First saw the patient at G, P. M., in bed, suffering no pain, but feeling sick and distressed. Carefully examined lungs, but could detect no sign of disease. Has occasional cough. DATE. o | S?1 °5 1 5 Tempera- tore. "cC u ’& QD © Pulse res- piration ratio. TREATMENT AND REMARKS. March 2, A. M. 3 96 March 3, A. M. 4 96 102 29 3.44 Still no crepitant rale. March 4, A. M. 5 96 105 28 1 3.44 Abundaut crepitus at base of right lung; slight crepitus at base of left lung. Ordered quin. sul. grs. xx at one dose; carb. amnion, mixt.; milk and beef tea. March 5, A. M. 6 100 104 32 1 3.13 Repeat quinine. Continue treat- ment. Oiled silk shirt. March 6, A. M. 7 108 105 28 1 3.96 Repeat quinine. Continue treat- ment. March 7, A. M. 8 100 103 5 32 1 3.13 Repeat quinine. March 8, A. M. 9 90 100.3 22 1 3.64 Quin. grs. ij. ter die ordered in place of dose of grs. xx. March 9, A. M. 10 80 98.5 16 1 5 Treatment continued. Profuse sweating. March 11, A. M. 12 80 99 15 1 5.33 Lung disease nearly disappeared. 4 This patient was only seen once daily, and the record is therefore oidy for the morning, and does not show the antipy- retic effect of the quinine; but according to the report of the nurses, each dose was followed by relief to the patient and reduction of fever, the latter rising again in the early morning hours. On the night preceding the 4th of March she was extremely ill; so much so that she insisted she was dying, and had the priest summoned to administer the last sacrament. There was no return of this extreme illness after the adminis- tration of the first dose of quinine, although the temperature arose equally high subsequently. The whole twenty grains of quinine were given between three and four o’clock, P. M., each day, and their effect in reducing fever lasted twelve or fourteen hours. The 5th, 6tli and 7th days of the disease were the worst. Defervescence began on the 8th day from the initiatory chill occupying 48 hours, but was not complete until the 10th day, ending in profuse sweating. There was no sudden crisis. Sweating still continued when attendance was closed, March 11th. The local disease was principally in the lower lobe of the right lung, posteriorly; the lower lower lobe of the left lung was slightly affected. There was no stage of complete hepati- zation, the crepitant rale being abundant duiing the whole course of the attack. Cough, expectoration and pain were insig- nificant. The pain complained of was in the right side, in front. Recovery was prompt. Average pulse respiration ratio J_. 3.87 Case II.—Croupous Pneumonia of both Lungs in an adult. James M., Irish, 37 years of age, stone polisher; is a drinking man; drinking by sprees, but sober in the interval; good con- stitution. Was taken sick March 5th, 1878, with chill followed by pain in the left side in front, and sweating. Painful cough. Con- tinued to work until March 9th. March 10th, first seen. Severe pain in cardiac region, causing dyspnoea and suppressed cough. Profuse sweating. Auscultation shows pneumonia in lower segment of left lung, liespiratiou in right side normal. 5 DATK. Day of Disease. Pulse. Tempera- ture. s "eS u E. x l> as Pulse res- piration, ratio. SYMPTOMS, ETC. March 10, A. M. 6 116 105 48 1 Rusty sputa; carb. amnion, gr. v 2.42 every 4 hours. March 11, A. M. 7 116 105.7 36 1 Pain and dyspnoea very distressing. 3.22 Quinine grs. xx at one dose. March 11, P. M. 100 102 28 1 General condition greatly iinprov- 3.57 ed ; cough and pain continue. March 12, A. M. 8 104 104 28 1 Quinine grs. xx repeated ; crepita- 3.71 tion in lower lobe, right lung. March 12, P. M. 100 102.7 32 1 Chloral grs. xx; morphia gr. i, to 3.12 relieve pain and produce sleep. March 13, A. M. 9 112 105 44 l Pain not relieved. Ordered bath 2.54 at 88° for 10 minutes in wash tub, in place of quinine. M’ch 13,3 P. M. 108 101.5 30 1 Great relief. 3.60 M’ch 13, 9 P. M. 92 100.3 28 1 Repeated chloral and morphia. 3.28 March 14, A. M 10 108 105 44 1 Fever rose again at 2, A. M.—14 hrs. 2.45 after bath. Repeat bath and in -i addition quinine grs. xx. M’ch 14, 5 P. M. 96 103 44 Middle and lower lobes of right 2.18 lung hepatized ; returning crepi- tation in left lung. M’ch 14,9 P. M. 88 100.5 32 1 Whiskey every 2 hours. 2.75 March 15, A. M. 11 84 102 36 1 Repeat quinine grs. xx. 2.33 M’ch 15, 9 P. M. 72 100.2 40 l 1.80 March 1G, A. M. 12 68 99.5 36 1 Left lung improving ; condition of 1.88 ; right lung unchanged. M’ch 16, 9 P. M. 76 100.3 32 1 Profuse sweating. 2.37 March 17, A. M. 13 64 99 36 1 Profuse sweating. 1.50 March 18, A. M. 14 78 99 32 1 Profuse sweating. 2.4.3 March 19, A. M. 15 76 100 2c 1 Profuse sweating. 2.78 March 20, A. M. 16 68 98 2t 1 Ordered cit. quinine and iron gr. v. 2.43 and cod liver oil f.?ss 3 times a day. 6 DATE. Day of Disease. Pulse. Tempera- ture. a * - a n © Pulse res- piration, ratio. SYMPTOMS, ETC. March 21, A. M. 17 68 24 1 2.83 March 22. A. M. 18 68 99 24 1 Appetite returning. 2.83 March 29, A. M. 25 76 Severe headache. Ordered brom. potas. grs. xxx ter die. Returning rales in right lung; lung normal; convalescing, still very weak. left April 1st. 28 80 but (Continued.) This case is a type of the severer form of croupous pneu- monia. Defervescence did not begin until the 10th day from the initiatory chill, and cannot be said to have been completed until the 16th day, a period of six days, so that the termination of the febrile symptoms was by lysis rather than crisis. It is to be noticed, as bearing on the question of diagnosis between croupous and catarrhal pneumonia, that on the twelfth day, when the pulse had returned to 68, and the temperature to 99.5°, the diseased process in two-thirds of the right lung continued una- bated. The record of the case shows most conclusively the antipyretic effect of quinine in gr. xx. doses, as well as of the tepid bath. On the morning of the 7th day the thermometer indicated a temperature of 105.7°; gr. xx. of quinine was administered, and in the evening the pulse had fallen to 100 from 116, and the tem- perature to 102°, a decline of 3.7° in seven hours. So on the following day there was a similar fall of 1.3°. On the morning of the 9th day the pulse was 112, and tem- perature 105°. Quinine having been given two consecutive days, it was deemed advisable to substitute the warm bath. In nine hours the pulse had fallen twenty beats, and the tempera- ture four and seven-tenths degrees. This could not be attrib- uted to the crisis—for on the morning of the 10th day, the fever again arose to 105°. On this day, the bath and quinine were both given, and devervescenee set in. Carbonate of am- monia was given all through the attack, aud beef tea and milk relied upon for uourishineut—both being taken freely. 7 The pleuritic pain in this case was very distressing and was complained of in front, although the pneumonic inflammation was mostly posterior. Average pulse respiration ratio _L Case III.—Croupous Pneumonia in the Lower Lobe of Right Lung, in a Young Child. Alvin M., male, aged 3 years ; plump, healthy child. Taken sick March 28, 1878. First seen March 20th, when pneumonia was developed in the lower lobe of right lung. Dyspnoea marked. DATE. D a y o f Disease. Pulse. Temper- ature. Respir’n. | Pulse-res- 1 piration ratio. SYMPTOMS AND REMARKS. 1878. March 29, A. M. 2 128 104 80 1 D60 W arm bath ordered every 4 hours. March 30, A. M. 3 128 101.7 40 1 March 30, P. M. 3 140 104 56 3.20 1 2.50 Quin. gr. v. at one dose. March 31, A. M. 4 148 103 40 1 do' do. do. April 1, A. M. 5 120 100.3 40 3.70 1 3.00 do. do. do. April 2. April 3. April 4. 6 7 8 101.5 28 Great improvement. Pulse, etc. not recorded. Convalescent. VisitB discontin- ued. The antipyretic effect of the quinine was very decided, but does not show in the chart, for the reason that but one visit was made daily after its administration was commenced. The ter- mination was by lysis—tin* period of defervescence extending over seventy-two hours, from the 5tli to the 8th day. Average pulse respiration ratio J_ Case IV.—Croupous Pneumonia in an Adult, Right Lung, Asthenic Form—Death on the 9 th Day. I). *1. B., aged 50 years, American, rather slender built, weight, about 140 tbs ; conductor on street cars, 8 March 9th, 1878.—Had slight chill, followed by fever, cough and dyspcena. Continued to work until evening of March 10th, but u laid off” and went to bed March 11th. eS c A c DATE. O x s? © 1 © © S-S a 5 *c8 t-j ‘5- ac © o $ ci.g ® -C TREATMENT AND REMARKS. P Ph © H © K 3 p. 2 PH * March 12, A. M. 4 108 104.8 30 1 3.60 Crepitant rale with marked dullness over middle lobe of right lung. “ Prune juice ” expectoration— harassing cough ; dyspnoea mark- ed; anxious countenance. Ordered quin. grs. xx. at one dose. Carb. ammon. and milk punch freely. Repeat quinine grs. xx. Beef tea and stimulants ad. lib.; dusky flesh on cheeks, oiled silk shirt aiound chest. M’ch 13, 2 P. M. 104 103.5 28 1 Upper and middle lobe right lung solid, and crepitant rale heard in 5 3.71 lower lobe. Dyspnoea greatly in- creased. Expectoration of same character and more in quantity. March 14, 12 M. 108 104 32 1 Condition about the same; expec- 6 3.37 toration same; cough very troublesome, preventing sleep. Ordered tepid bath to be followed by quinine grs. xx.; morphia and chloral mixture to control irrita- ble cough. Beef tea and milk punch continued. Expectoration less in quantity and not so bloody; cough in a mea- March 15, 12 M. 7 96 102.5 sure relieved by anodyne mix- ture. Quantity of whiskey in- creased to oz. ss every two hours. March 16, A. M. 100 103 34 1 Passed a bad night. Watchers 8 24)4 went to sleep, so that he got neither medicine nor nourish- ment during the night. Got out of bed himself to get water. Right lung entirely hepatized ; dyspnoea very distressing ; cyan- osis marked; larynx rises and falls during respiration ; supra- clavicular spaces sink in. Or- dered camphor grs. iij. in emulsion every two hours, and to push whiskey and beef tea. Dyspnoea still greater and cyanosis more marked. Treatment continued. M’ch 16,10 P.M. 8 104 103 36 1 Dying. 2.88 March 17, A. M. 9 120 103 40 1 Died at 2 P. M. 3.00 9 In this case there were prodromal symptoms for two weeks before the onset of the disease. The patient’s habits of life had formerly been irregular, but for the past several years had been correct. The record of pulse, temperature and respiration would not indicate a severe attack of the disease, but the accompanying symptoms of distress, cyanosis and “ prune juice” expectora- tions pointed clearly to a severe case. The pulse, three hours before death, was but 120, and temperature 103°. It is a matter of great regret that just at the most critical period of the disease—the night between the 7th and 8th day— he should have been neglected by the sleepiness of those in charge of him. Had the stimulants and nourishment been kept up regularly during this time, and the patient been prevented from getting up out of bed, a different result might reasonably have been expected. The record of pulse and temperature shows a remarkably low average for a fatal case. Average pulse respiration ratio _i_ Case V.—Croupous Pneumonia, Lower Lobe of Right Lung, in an Infant. Ed. O’C., healthy infant, aged 22 months. Taken with chill followed by fever, March 29th, 1878. Supposed by family to have intermittent fever. Was not seen until 4th day, when pneumonia was found developed in lower lobe of right lung, crepitant rale being distinct, with dullness on percussion. DATE. Day of Disease. Pulse. cS is a P P V H a *35 u 'S. s Pulse res- piration ratio. REMARKS, April 1, A. M' 4 192 10« 48 1 * 4.00 Warm bath anil quiu. grs. iv. at once. April 1, P. M. 4 160 102,f> 52 1 3.07 April 2, A. M. 5 160 103 56 1 2.85 Repeat bath and quinine. April 3, A. \1. 6 112 98 40 1 2.80 Attendance discontinued. 10 Average pulse-respiration ratio _L Termination by crisis on the 6th day. The violence of the symptoms on the 4tli day, as indicated by pulse of 192 and temperature of 106°, were such as to create serious doubts as to the result; but the prompt effect of the warm bath and quinine in alleviating the alarming condition was altogether satisfactory. The temperature fell 3.5° and the pulse 32 beats per minute in six hours, which was not due to the crisis of the disease, the temperature rising to 103° the following morning. Case VI.—Croupous Pneumonia, affecting whole of Right Lung, in a Young Child. Louisa H., German parentage, 3£ years old; robust, healthy child. Taken sick with chill, followed by fever on the 1st of April. Was sent for on the morning of April 2d, on account of violent convulsion which had been preceded by vomiting. DATE. o ® ao s?s Pulse. Tempera- ture. a "cS — ’3. 3C V X Pulse res- piration ratio. TREATMENT AND REMARKS. April 2, A. M 2 160 104 — Convulsion and vomiting. Calomel grs. i. every 4 hours; also brom. potas. grs. v., eo. spt. aeth. gttxv. April 2, P. M. 148 105.5 — every 4 hours alternately with calomel. April 3, A. M 3 148 105.7 Diarrhoea. Stop calomel. Warm bath and quin. grs. v. April 3, P. M. 132 103.5 1 2.50 1 2.00 Have been examining lungs at each visit, but found no sign of disease until now, when pneumonia is discovered in the base of right lung. Carb. ammon. grs. iv. every 4 hours. April 4, A. M. 4 140 105 56 Dr. 8. C. Bnsey in consultation. Quin. grs. v. repeated. Syr. sen- egae added to carb. amiuon. inixt. April 4, P. M. 128 103.5 44 Beef tea and milk punch for nour- ishment. April 5, A. M. 5 144 105.8 76 1 1 80 1 2315 Dr. Busey in consultation. Nearly whole of right lung hepatized Quin, repeated. April 5, P. M. -• 132 103 56 Orders left to repeat quin, if fevei in- creased, and it was done at 2 A. M. 11 (CONTJNUKI).) rt -H ® s » a q 58 2.2 . DATe. Pulse 5*2 a 3 t * i s ® H M Pulse pirat ratio TREATMENT AND REMARKS. April 6, A. M. 6 130 105.304 1 l)r. Busey in consultation. 2.12 5 o’lock, P. M. 132 103.564 1 An attack of syncope, apparently from cough and dyspnoea. Wliis- 2.00 1 key administered freely. 9 o’clock P. M, 128 104 00 Has revived. 2.13 April 7, A. M. 7 132 103.556 l Dr. Busey in consultation. 2.35 April 7, P. M. 130 105 00 1 2.20 Repeat quinine. April 8, A. M. 8 110 98 .. 1 Dr. Busey in consultation. April 8, P, M. 92 98 32 2.87 April 9, A. M. 9 120 101.556 1 Headache. 2 14 April 10, A. M. 10 116 98.5 .. 1 Returning rales in right lung. April 11, A. M. 11 92 28 364 Average pulse-respiration ratio -i. Tlie bowels were loose from the start, sufficiently so to re- quire use of starch water and laudanum enemas and bismuth powders to cheek the frequency of' the loose watery discharges. The pneumonic iutiammation did not develop so as to be recog- nized until the evening of the .'hi day, although the lungs were carefully examined each visit in consequence of the doubt as to the diagnosis. The local disease was confined to the right lung, but so crippled the entire lung that death was imminent from suffocation from the 5th to the 7th day of the attack. The crisis occurred suddenly on the Sth day, with relief of all the symptoms except the frequent respiration, which was governed by the local disease iu the lung. The effect of the quinine was very regular in reducing the temperature from t.5° to 2.8° after each administration, this effect lasting about twelve hours. In this case tin* administration of the quinine was followed each time by quiet sleep of three or four hours— with a fall iu pulse and temperature indicated. 12 Case VII.—Croupous Pneumonia at Base of Left Lung, in a Young Child. Louis H., aged 5 years, strong, hearty child. Taken sick on the night of April 9th with chill. First seen evening of April 10th, when the crepitant rale was abundant at the base of the left lung. DATE. | Day of | Disease. Pulse. (h ® ® aj= S* d 1h *P- ac 4. Ph Pulse-res- piration ratio. TREATMENT AND REMARKS. April 10, P. M. 2 140 103.5 44 1 3.18 Flaxseed poultice to chest. Fever mixture of sweer. spirits of uitre and spirits uiiudererus. April 11, A. M. 3 132 103 44 1 aToo April 12, A. M. 4 132 100.3 40 l 3.30 April 13, A. Al. 5 100 98.5 32 1 3.12 Resolution of the luug disease commenced. This case is interesting as illustrating the mild or abortive form of croupous pneumonia. The diagnosis was clear, but the diseased action in the lung was hardly set up, before it began to decline; and, on the 5tli day, when the crisis occurred, he was to all appearance well. 1 had an exactly similar case in the child of Mr. J. H. IS., aged 4 years, the notes of which 1 have unfortunately lost. The initiatory fever in this latter case however rose to 105.5°, but the local disease aborted just as above, and the patient was well suddenly. 1 believe that many of the eases of so- called u ephemeral ferer ” referred to by the older writers, belong to this form of croupous pneumonia. Tetmination by crisis on 4th day. Average pulse respiration ratio J_ Case VIII.—Croupous Pneumonia in Adult in Lower Lobe of Left Lung. D. P. M., aged 58 years, cabinet maker by trade, slender build and rather delicate in appearance. Was taken with chill April 15th, 1878. Had been troubled with a cough for two weeks previously. DATK. Day of Disease. Pulse. Tempera- ture. ~ce (H ’a 35 ab c £.2 . ® .2 REMARKS AND TREATMENT. .2 S -g - a, April 18, A. M. 4 104 104 20 1 Puwum. of lower lobe of left lung. 5 20 Quinine grs. xv. April 19, A. M. 5 88 102.5 18 1 Cough troublesome with pain, left side. No rusty sputa. April 20, A. M. 6 104 10:1 18 1 Repeat quinine. Garb, ammon., grs. ?k77 v- «ver.V 4 hours. April 21, A. M. 7 84 100.5 Quinine ordered grs. iij 11 times a l day. Profuse sweating. 4.25 April 22, A. M. 8 68 98.7 16 April 25, A. M. 11 52 98 12 1 Average pulse respiration ratio, _L This patient was very weak and recovered strength slowly. The previous history, as indicated by the symptoms of bron- chial catarrh preceding the onset of pneumonic inflammation, would seem to point to catarrhal pneumonia, but rapid course of fever, terminating in eri«i», between the 7tli and 8th day, clearly establish the diagnosis of croupous pneumonia. As in Case IV, there were present prodromal symptoms for two weeks before the iniatitory chill. Defervescence carried the pulse and respiration below the normal. Case IX.—Cron,pom Pneumonia in an Adult in Lower Lobe of Left Lung. John D., 45 years of age. Never sick, but not robust. Was taken with a chill April 18th, 1878. First saw him April 20th, when he was sufering with acute pain in left side, in front, painful cough with rusty sputa. Auscultation discovers pneu- monia in the lower lobe of the left lung. 14 DATE. Day of Disease. Pulse. Temper- ature. | Respir’n. Pulse-res- piration, ratio. TREATMENT AND REMARKS. April 20, A. M. 3 120 103.2 18 1 6.66 Fever mixt. of sweet spirits nitre and liq. am. acet. Cliroral and morphia to relieve pain. April 21, A. M. 4 120 104.5 28 1 A33 Quin. gr. xv. at one dose. April 22, A. M. 5 11G 103.2 28 1 4.14 Quin, gr. xv. repeated. Left lobe of left lung hepatized. April 23, A. M. 6 120 102 30 l 4.00 Quin. gr. xv. repeated. Carb. am- mon. gr. v. every 4 hours. April 24, A. M. 7 92 99 24 1 3.83 1 5.66 Diarrhoea. Profuse sweating. Carb. ammon. stopped. Quinine gr. iij. 3 times a day. Beef-tea and milk punch. April 25, A. M. 8 68 95.5 12 Returning crepitation in lung. April 28, A. M. 11 ■' )* Patient down-stairs sitting, but very weak. Crepitation rale still distinct in lower portion of left lung. Average pulse, respiration, ratio _i_ Termination by crisis on the 7th day. On the 8th day the temperature fell to 95.5°, with respirations only twelve per min- ute. There is a very great similarity between this ease and tin* preceding one, the recovery from the lung disease being pro- tracted. Defervescence below the normal, both as to tempera- ture and respiration. Case X.—Croupous Pneumonia in Upper Lobe of Right Lung in a Young Child. Samuel S., aged 3 years, robust, healthy child. Had attack of spasmodic croup May 24th. Was taken with chill, followed by fever, quick breathing and Hushed face May 26th, 1878. 15 DATK. O x • . CB © £ " J£ 73 X V* aia £ Tempera- ture. a *08 — *5. X - M Pulse res- piration ratio. REMARKS. May 27, A. M. 2 148 103.8 44 1 3.36 Warm bath ordered. May 27, P. M. .. 132 101.5 44 1 3.00 Pneumonia of upper lobe right lung. May 28, A. M. 3 148 102 52 1 2^84 May 29, A. M. 4 152 104.5 72 1 ‘ZTo Wet towel around chest renewed every two hours ; carb. ammonia mixture. May 29, 9 P. M. .. |132 102 56 l 235 May 30, A. M. 5 120 101.7 40 1 3.00 May 31, A. M. 6 120 101.7 40 1 33)0 June 1. 7 104 99 40 1 2.60 Resolution of lung disease prompt and complete. Average pulse respiration ratio -L Tennination by crisis on the 7th day. Attention is called to the application of the wet towel in in- fants as a substitute for bathing. This child struggled and fought so against the bath that it was deemed unwise to persevere in its use, the excitement attending its administration antagonizing its good effects. A large towel was folded lengthwise, dipped in water at temperature of 80° and wrapped around, the chest being covered with dry flannel. This was changed every two hours, with tin* most satisfactory effect. The child does not rebel against this treatment, it is quickly done, and in my ex- perience, is a most valuable aid in reducing temperature in infants. When we bear in mind that in early life the limbs bear a much smaller proportion to the body than in adults, and that in children the intensity of fever is greatest in the body and head, the value of this mode of application becomes apparent, and when conjoined with cold applications to the head, fulfills the whole indication of the antipyretic use of M ater. I am speaking 16 only of young children, and in them this has been a favorite method of controlling fever for several years. Of course, where the fever is the more intense, the wet towel must be changed the more frequently. Case XI.—Croupous Pneumonia, occurring during the incubation of Measles and followed immediately by that disease.—Pneu- monia in middle lobe of right Lung. W., aged 3 years, girl, healthy child. Has been exposed to contagion of measles for a week, another child being down sick with it in the same house. Has had fever every other day for several days, and a teasing cough. Was taken June 1st, in the morning, with a chill, and about noon had a violent convulsion. a ? a U . 'a g.S DATE. w ao & £ » .2 tkkatmkst and kkmakks. a go Qq ao 'B Ph 3 = V H So" « £ 2 +3 a -S g P-l Jane 1, 1876... 1 Convulsion following chill. — Brom. potas. grs. vi., elix. val. amrnon. £3b every 3 hours for 3 doses. Rested well all night. June 2, 12 M. 2 224 Capillary congestion almost as dark as scailatina. Cincho. quin. grs. iij. every 6 hours; spts. aeth. nit. June 2, 4 P. M. 200 104 - - - - and liq. ammon. acet. for febri- fuge; occasional doses o: bromide with tr. opium gtt. iij. June 3, 9 A. M. 3 180 105 .... June 3, 12 M. 103.3 June 4, 2 A. M. 4 180 104.3 .... Quinine grs. iij. June 4, 8 A M. 144 101.4 Irritating cough of most distressing character and almost continual; child greatly exhausted; percus- June 4, 10 A. M. .. 160 100 .... sion dull over middle lobe of right lung, which also gives crepital rale on auscultation. Ordered tr. opii deod gtt. iv. every 4 hours until spasmodic cough is relieved. June 4, 5 P. M. 154 105 Cincho quin. grs. iij.; carb. ammon. andsyr. senegaein emulsion; soap liniment freely to chest. June 5, 5 A. M. 5 140 99-5 T * Cough still distressing, no appetite. June 5, 12 M. -- 136 98.3 30 Occasional doses of opium as re- quired; beef tea and milk punch 4.53 ad libitum. June 5, 5 P. M. 99.6 36 Dr. C. E. Danner in consultation. J une 6, 8 A. M. 6 134 98.4 40 1 3.35 Dr. H. in consultation. '1 reatment continued. June 6, 8 P. M. 150 103 44 l Eruption of measles beginning to ap- 3 40 pear. Resolution taking place in lung. 17 DATE. Day of Disease. Pulse. E 8.8 a 5 H | u^jidsdjj Pulse res- piration ratio. TREATMENT AND REMARKS. June 7, 6 A. M. 7 120 100 30 1 4.00 Dr. H. in consultation. June 7, 10 P. M. •• 160 103.2 60 1 2-66 Warm bath. June 8, 1 A. M. 8 160 103.2 70 1 2.28 Quinine grs. iij. June 8, 8 A. M. 144 102 66 1 2.18 June 8, 6 P. M* 164 104 72 1 2 -25 Collapse in middle lobe of right lung. June 8, 8 P. M. •• 170 105.2 70 1 2.42 Quinine grs. v; carb. ammon. mixt. and stimulants freely. June 9, 2 A. M. 9 144 102.460 1 :M0 June 9, 6 A. M. 128 99.6 54 1 2.37 Oiled silk shirt. June 9, 8 P. M. 144 101 36 _L 4.00 Sulph. quin. grs. v. June 10....... 10 120 98.236 1 3.33 Eruption fading; appetite return- ing. Phosphat. emulsion of cod- liver oil. (COKTUCUED.) Pulse-respiration ratio j-L Crisis occurred on the 5th day of the pneumonia. On the 6th day from the initiatory chill the eruption of measles begun to appear, with an increase of temperature to 103°. On the 8th day collapse of that portion of the lung affected by the pneu- monia occurred, with sudden aggravation of all the symptoms. The most noticeable effect of the rubeola poison in the system was the intense irritative cough—the regular measles cough— so greatly aggravated that the father, who is a physician and watched the case most carefully, thought several times that she must die from exhaustion. This cough was relieved by full doses of opium and gradually disappeared as the eruption faded. The collapse of the lung was the only other symptom which could be ascribed to the complication of the two diseases, each disease with these two exceptions—of the intense irrita- tive cough and the collapse—running a normal course as though the patient had but the one at a time. 1 must confess that 1 watched the development of the measles with great anxiety, 18 fearing and expecting the occurrence of an acute catarrhal pneumonia which would have proved quickly fatal in the weak- ened condition of the little patient. The collapse of the lung rapidly disappeared under the free administration of tonics and stimulants. The subsequent progress of this case was entirely favorable, and at this date (July, 1878), no trace of the severe illness re- mains, except a slight roughness of voice. The following tables present in a condensed form an analysis of the more prominent symptoms occurring in the foregoing cases: CASE. 6 5C < Average Pulse. * Average Temp * | Average 1 Pulse Resp’n | Ratio. ONSET OF DISEASE. POKTION OF LUNGS AFFECTED. 1 48 F 99 103.3 1 T87~ 1 Sudden ; ushered in by chill. Lower lobe right lung principally; left lobe of lelt lung slightly. 11 37 M 105 103.4 2330 1 2.80 Not sudden ; chill, a f t e r w h i c h worked 4 days before takiug ti bed. Lower lobe of left lung and middle and low- er lobe of right lung. III 3 M 133 102 0 Sudden ; if chill did i ot know. Lower lobe right lung. IV 30 M 100 103.4 1 3.25 1 3.18 Prodromal symp- toms for 2 weeks; slight chill at onset. Whole of right lung. V 22$ M 17u 103.8 t Sudd, li ; chill. Lower lobe right lung. VI 3* F 123 104.3 1 2.43 1 3.12 Sudden; chill ush- ered in by con- vulsions. Whole of right lung. VII 5 M 135 102.3 Sudden ; chill. Lower lobe left lung. VIII 58 M 95 102.5 1 4.88 Chill ; prodouiata for 2 weeks. Lower lobe left lung. IX 45 M 119 103.2 i 1 iT7 Sudden; chill. Lower lobe left lung. X 3 M 130 102.4 1 2.78 1 2.83 Sudden ; chill, pre- ceded by spas- modic croup. Upper lobe right lung. XI 3 F 178 103.3 Chill; convulsiouB, preceded by a remittent fever; sudden. Middle lobe of right lung. * Average pulse and temperature are estimated to time of beginning defervescence. § Months. f On the 4th day of case V the temperature arose to 106°, the highest observed in any Of the cases. { In case IX, on the 8th day, the temperature fell to 95.5°. 19 CASK. FAIN. COUGH. SPUTA. TKKMINATION. I Right Hide in front. Not severe. Neither f r e - quent nor distressing. Not significant By crisis on Hth day, defervescence 1 a s t - ing 48 hours. Profuse sweating. Recovery prompt. 11 Very severe in cardiac re- Kiou. Very frequent aud suppres- sed on ac- count of pain. Rusty, abun- dant. By lysis; defervescence began on Utth day, and was not complei e until lfith day, a pe- riod of 6 days. Pro- fuse sweating. 111 Unable to lo- cate it on ac- count of age. Insignificant. Not seen. By lysis from 5th to 8th day, occupying 72 hours. IV Severe, but marked b y dyepmea. Very haras- sing, of irri- table char- acter. “ Prune juice” in character. Very abun- dant. Death on 9th day from asphyxia. V Not noticed. Insignificant. Not seen. By crisis on 6th day. Defervescence less than 24 hours. VI Not noticed. Troublesome. Not seen. By crisis on 7th day. Defervescence less than 24 hours. Vll None. Insignificant. Not Heen, By crisis on 4th day. Defervescence less than 24 hours. VIII Pain in left Hide anter- iorly. Trouble some from giving pain. Not rusty. By crisis on 7th day. Defervescence less than 24 hours. Pro- fuse sweating. IX Pain severe iu left Bide an- teriorly. Painful cough liusty. By crisis on 7th day, Defervescense less than 24 hours. Pro- fuse sweating. X Not noticed Insignificant. Not seen. By crisis on 7th day. Defervescence less than 24 hours. XI Not noticed. Cough parox- ysmal, ii imi- tative. most haras sing and exhaust- ing. Consti- tuted a dan- gerous ele- ment iu the disease. Not seen. By crisis on 5th day. Defervescence less than 24 hours. Au examination of these tables of summary of symptoms shows: 1st. As to age, that six of these eases were between tin* ages of one and tive years. Five eases were adults between ages of thirty-seven and fifty-eight years. There was no case between the age of tive and thirty-seven years. 20 2d. As to sex, eight were males and three females, or a per- centage of males of 72.7 to 27.2 of females. 3d. Pulse.—The average pulse during the febrile stage for the adults was 105, while the same for the children was 145 beats per minute. Nothing peculiar was noticed as to pulse, except that in the asthenic cases it was slower than in the sthenic cases, whereas it might naturally have been expected to be more rapid from the enfeebled state of the patient. The pulse kept pace very regularly with the temperature curve. 4th. Temperature.—The average temperature for the eleven cases to the commencement of defervescence was 103.1°, the highest recorded being 100° in an infant of twenty-two months, and the lowest 95.5° in Case IX, where the crisis oscillated the temperature to three degrees below the normal without appar- ent detriment to the patient. The typical morning depression and evening rise in temperature were interfered with by th6 anti- pyretic treatment and hence do not show in the record. 5th. Pulse-Respiration Ratio.—In the normal state of health the relation between the pulse and respiration is that of 1 to 4£, the pulse being taken at 72 per minute and respiration at 16, for an adult. About the same proportion exists in children, both being increased in the same ratio according to age. The same thing is true in regard to febrile diseases which quicken the heart beats and breathing. The relative proportion is maintained as long as there is found at the same time no morbid condition of the thoracic, viscera, but as soon as heart or lungs become implicated by diseased processes, the normal pulse-respiration ratio of one to four and a half is destroyed, and in the case of lung disease, other things being equal, the degree of variation becomes an accurate measure of extent to which the lung tissue is implicated. It is, therefore, a most valuable factor in the early diagnosis of the form of lung inti ami nation at present under considera- tion, especially because, being an infectious fever, ah initio, the local lesion does not become apparent in many cases for two or three days (as in Case Vi of this report) and the symptoms may all be referable with equal propriety to any of several of the zymotic fevers. 21 While, however, other symptoms fail to furnish any differen- tial elm* as to the previse nature of the fever, which we are alumt to be called upon to battle with, if the ratio between the pulse and respiration is augmented to any marked degree, we may be sure that in a very short time there will be found tin* crepitant rale, and dullness on percussion over some portion of the chest. We have above an average* pulse respiration ratio in the whole number of eases of J_, but it would be more exact as ex- 3.33 7 expressing tin* true ratio existing between tin* pulse and resin- ration, in typical cases running a regular course, if we exclude eases VIII and IX, which are exceptional in presenting a pulse- respiration ratio less than normal, being rerjactively -i.and J_ Leaving out of account these two cases, we have from those remaining an average J_, which probably expresses very nearly the true ratio existing between these prominent symptoms in croupous pneumonia. (ith. The onset of the disease.—An examination of the above table will show that the attack was ushered in suddenly by a chill in eight of tin* cases, and in two (VI and XT) in children, the succeeding fever was accompanied by convulsions. In three cases, tin* commencement was gradual, in two of which (IV and VIII) then* were decided prodromal symptoms for two weeks. A chill was present in all the eases, except the third, and in that it was not observed, although from the age (3 years) of the child, it might easily have been overlooked. 7th. The hnuj or part of lun u Total 13 u Upper lobe of left lung attacked 0 times. Lower lobe of left lung attacked 5 “ Total 5 “ 22 In several instances more than one lobe was inflamed in indi* vidual cases, so that the whole number of lobes attacked in the eleven cases was eighteen. Marked preference is shown for the lower lobes, they being singled out in eleven out of the eighteen times. Both lungs were affected in two cases. The right lung was involved eight times, and the left lung tive times, giving a pro- portion between the two of eight to tive, which corresponds very nearly with the statistics of the latest authorities. 8th. Pain.—In none of the cases occurring in children, was pain in the chest observed, and if present in any degree was certainly not severe, and could not be located. In all the severe cases in adults, pain was a prominent symp- tom, and a cause of much suffering. In every case where present, it was felt in front to one side or the other of the median line, according to the lung affected, while the pneumonic inflammation invariably approached nearer the surface—posteriorly. 9th. Cough.—Nothing peculiar to the disease under consid- eration appeared in the cough. It was present in all the cases, but in those unattended by severe pain from the pleuritic com- plication, it was insignificant. Where pain was marked, the cough became the most distressing, by aggravating a torment, which was quiescent as long as the patient remained undis- turbed. In the fatal case, the cough was peculiarly harrassiug, being almost constant, of a hacking character, and only absent from the influence of narcotics. In the 11th case, the character of the cough was evidently influenced by the measles complication, and was of so serious a nature, that dangerous exhaustion resulted. 10th. Sputa.—Children under the age of five years very rarely expectorate, and in the six infantile cases no sputum was seen, although in some it was evidently abundant from the loose cough, and was swallowed. Of the five adults it was colored by blood in three cases, and not so in two. In case IV, it was abundant, like “prune juice,” ami in the result verified the unfavorable prognosis of older writers from the presence of this symptom. 11th. Termination.—Termination was by crisis in eight cases; 23 by lysis in two, and death one. The crisis occurred in the first set as follows: In 1 case on the fourth day. In 1 case on the fifth day. In 1 case on the sixth day. In 4 cases on the seventh day. In 1 case on the eighth day. In the second set of two cases, terminating by lysis, the defervescence began in one on the oth day and was complete on the 8th ; and in the other case did not commence until the 10th day and was not complete until the lOtli. The exact time occupied by defervescence, where less than twenty-four hours, could not be determined, on account of suffi- ciently frequent daily visits not being made; nor, for the same reason, could tin* hour of the day when defervescence began be definitely fixed, but according to the reports of the nurses the improvement began shortly after the morning visit (11, A. M.), and continued through the night, taking the place of the usual evening exacerbation. In seven cases, the time occupied in the reduction of temper- ature to the normal degree was lest than twenty-four hours; in one case it was forty-eight hours; in one, seventy-two hours, and in one six days. Profuse sweating accompanied the defervescence in four cases, which were also the most severe. It will appear from the above record that the crisis may occur anywhere from the 4th to the 10th day, the 7th day being the one on which it most frequently takes place; also that the time of defervescence in a particular case is influenced by its severity, being earlier in mild eases and retarded in the graver forms. .Jurgensen (Ziemsen’s Cyclop., vol. v., p. 54) gives a table of 721 eases, terminating all the way from the 2d day (eight rases) to the 18th day (two eases), of which 1 <»."» came to an end on the 7th day. The eases above reported are susceptible of division into two groups, viz: sthenic and asthenic. In the former group are eight eases, including all the infants, which present no pecu- liarities, but are typical cases of croupous pneumonia. In the latter group, the asthenic, are three eases (IV, VIII, IX) 24 which differ from the former in several important respects worthy of especial notice. Two cases (IV and VIII) were pre- ceded for two weeks by prodromata of bronchial catarrh and malaise, which statistics show to be not common in this form of pneumonia. In all three the pulse, temperature and respiration were very low, considering the gravity of the cases. In Case IV the pulse ranged from 9(5 to 120, the latter rate being but a few hours previous to death, when the the temperature was but 103° and respiration 40. In Cases VIII and IX, the average pulse respiration ratio is 2L and — respectively, being in both less than that of health. In Case VIII, defervescence carried the pulse down to 52 and respiration down to 12 per minute, and in Case IX the temperature fell to 95.5° and respiration to 12—all below normal. A report of this character does not allow space for a full discussion of the question of diagnosis which might be opened by the consideration of these latter three cases, but it is clearly suggested, from a clinical point of view, that eases do con- tinually occur where the diagnosis between croupous and catarrhal pneumonia will hinge upon the termination by crisis or lysis—about the usual time for such termination in the natural history of the former disease. In Cases VIII and IX the termination was by crisis on the 7th day. In case IV death on the 9th day, but the history and symptoms so closely parallel the other cases that the diagnosis is not in doubt, and could life have been prolonged a day or two longer, there was every reasonable hope that the crisis would have taken place. As to the preceding bronchial catarrh, whether that was a true prodroma or merely an ante hoc, is an open question—for there is no reason why croupous pneumonia should not be developed during the existence of a bronchitis, the same as though the latter did not exist, or just as in case XI it made its attack during the forming stage of measles. Treatment.—It is of the utmost importance in connection with the treatment of croupous pneumonia, to take into considera- tion its natural history. It is an intensely febrile disease, self- 25 limited—running its course more rapidly perhaps than any other zymotic disease, and terminating with abrupt suddenness about the seventh day. This order of sequence in the symptoms we may confidently predict under any plan of treatment not absolutely injurious, for the prognosis is in healthy subjects most favorable, being even more so in children than in adults. It is a disease in which the physician can well afford to bide his time, and bear out the old rule, which I had firmly impres- sed upon me, when a student, by my venerable preceptor, the late Dr. Joshua Riley,—“To be sure if you can do no good, at least to do no harm.” There is no malady in the catagory of medicine, which yields to the medical attendant so much honor from the patient and his friends as the one under consideration, because in the very height of severe illness, the fever often reaching its maximum just before tin* crisis, the sick man is suddenly well, and of course the doctor and his last remedy get the credit for the cure. Nor is it unfrequently the case that the physician himself is deceived, taking the post hoc for the propter hoc, and thinking that lie has found a specific remedy. Happily this multiplica- tion of specific remedies has received a check by the attention now given to the study of the natural history of disease, and tendency is to reduce rather than add to the already cumber- some materia medica by interposing a more correct knowedge of what would be the symptoms, course and termination in typical cases unintiuenced by drugs. With regard to the disease which is tin* subject of this paper, this has of late years been very (dearly set forth, and the duty of the medical attendant in tin* premises is very much simplified. It is to guide the case, guard against excessive fever, support the strength and watch for complications, in other words anti- pyretic and supporting. The danger to be apprehended is prin- cipally two fold, indirectly from cardiac debility due to intense fever and lung obstruction, and directly from tin* extent of the. lung disease. The high temperature is to be combatted by baths and qui- nine. A reference to the temperature record of the above cases 26 shows characteristically the effect of this treatment upon the fever heat, but it does not and cannot express the great relief accompanying it to the patient, of distressing symptoms. I have never used cold baths in this disease, but have prepared water at a temperature of 90° and reduced it ten degrees during the fifteen minutes occupied in administering it. Not that I believe any risk would be run by making the bath cold, but experience goes to show that quite as great reduction of temperature is obtained from the above graduated bath, with certainly greater comfort to the patient, and less violence to the prejudices of friends. If we consider for a moment the modus operandi by which the bath is ail effective measure in reducing temperature, I think we will be disposed to admit that the warm bath should have the preference. The siin is the organ by which the balance of temperature is preserved between the internal structures and external surface, and through the agency of the blood. A very great extent of surface in the capillary vessels of the skin, is exposed to the cooling influence of the external air with every pulsation of the heart, and the extent to which the surplus heat of body combustion is got rid of, is exactly in proportion to the amount of blood so exposed to the air in the skin, and the condition of the skin at the time. The application of cold contracts the capillaries of tin* skin, and drives the blood away from the surface towards the inter- nal organs. This is the effect of a cold bath, and although the reduction of temperature in the blood still remaining in tlie skin is greater than from a tepid bath, still the aggregate effect will be less. The warm bath relaxes the skin and invites blood to the sur- face, while the difference in temperature between water at 90° and fever heat (104° or upwards) is quite sufficient to give a decided clinical result. In addition, the absence of shock and greater feeling of com- fort to the patient is an advantage of the warm bath not to be overlooked. In some of these cases, where the convenience of a bath tub 27 was not to be had, a common washing tub was used, the patient sitting in it, covered over tin* shoulders with a blanket, and this was found to be an efficient substitute. Whenever the patient became prostrated from the fever, or oppressed by tin* dyspnoea, the baths were discontinued and quinine relied on as an antipyretic. In children, if the baths were the occasion of struggling and screaming, they were not insisted on, the wet towel* and quinine being resorted to. The dose of quinine given to adults was from grs. xv to grs. xx, and was found to be sufficient. The reduction in temperature varied in different cases from 1.3° to 4.7°, and lasted about fourteen hours from the time of administration. A dose given at mid-day would show decided effect in three hours, reach its maximum at b o’clock, P. M., and the temperature would begin to rise about 11 o’clock, A. M. In the severer cases tin* temperature would be again the following morning as high as before its administration. In the milder cases the fever did not appear to rise as high any more after tin* tirst dose of quinine. In some of the cases, especially marked in Case VI, it pro- duced a decided hypnotic effect, every full dose being fol- lowed by quiet sleep. Dr. S. C. Bussey, who was in consultation in this case, said he had frequently noticed the same effect. He had had his attention first called to it by Dr. ,Jas. C. Hall, of this city, a most acute observer, who had been in the habit for years of giv- ing quinine at bedtime, with the double purpose of promoting sleep and at the same time avoiding the annoyance of noises in head occasioned by this agent. Stimulants were administered as required. Carbonate of ammonia as a special cardiac stimulant where the respiration was embarrassed. Milk and beef tea were relied on for nourishment. Season of the Year. All the cases here reported occurred between the months of February and June inclusive, and eight out of tin* eleven were attended in March and April, four for each month. Se*> Case X. 28 One case was noted in February, one in May, and one in June, the latter having its onset on the first day of the month. From the occurrence of the last ease to the present date (September 10th) I have seen but one ease, a child three years of age, who was taken sick August 28th. By courtesy of the Health Officer of the District of Columbia, Dr. Smith Townshend, I am enabled to append a report of 1915 deaths from pneumonia during a period of six years and eight months, from January 1st, 1872, to July 31st, 1878. DISTRICT OF COLUMBIA, BOARD OF HEALTH. OFFICE OF HEALTH OFFICER. Washington, August 10th, 1878. Dr. I). IF. Prentiss, 1224 Ninth Street N. IF. Sir—In reply to your letter of the 2d inst., I transmit here- with table showing number of deaths from pneumonia in flu* District of Columbia from January 1, 1872, to August 1, 1878. Prior to August, 1874, there was no law requiring physicians to furnish certificates of deaths to the Health Department, and no permits for burials were required, hence the “table” is not reliable prior to that date, although it contains every case reported to the Health department to that date. Begretting my inability to furnish more complete information, I remain, very respectfully, Smith Townsiiend, M.D., Health Officer. Statement of Deaths from Pneumonia in the District of Columbia, January 1st, 1872, to July 3lsf, 1878. YEARS January. February. March. April. May. June. July. August. September. October. November. December. TOTAL. 1872 12 21 20 22 17 11 1 9 3 10 9 16 151 1873 27 14 13 13 6 6 2 4 5 7 13 110 1874 22 14 26 19 19 2 6 *18 9 20 18 40 213 1875 81 69 87 47 19 17 4 14 14 24 28 42 44(1 1876 51 52 78 66 41 8 7 11 14 16 22 31 397 1877 58 61 54 33 25 18 6 7 5 13 21 26 327 48 40 45 34 49 35 20 .271 1 1 Totals. 299 271 323 234 176 91 50 61 49 88 105 168 1915 'Absolutely correct Horn August 1874. to iiud including July, 1878. Prior to August ’74, the records were very incomplete. Physicians not being required to make returns We have no records prior to 1872. This statement would appear at first sight to indicate an extraordinary mortality for this disease in the District of Co- lumbia; and such would be the fact, were they all cases of croupous pneumonia. It includes, however, all the forms of pneumonia—catarrhal pneumonia especially of old persons and young children, of invalids and consumptives, and not unlikely many cases of capillary bronchitis and pulmonary collapse. The statistical value therefore, in a mortuary sense, is lost, but the relative value as to frequency of occurrence at certain seasons of the year remains but little impaired. Thus during the four months from January to April, inclu- sive, there are deaths to 788 for the remaining eight months, and for the six months from December to May, inclu- sive, there are 1471 cases against but 444 for the other six months, showing it to be a disease of winter and spring months.