NATIONAL LIBRARY OF MEDICINE Washington Founded 1836 U. S. Department of Health, Education, and Welfare Public Health Service u> SYSTEM OF SURGERY. BY J. M. CHELIUS. TRANSLATED FROM THE GERMAN JOHN F. SOUTH. VOL. III. A * SYSTEM OF SURGERY, BY J. M. CHELIUS, DOCTOR IN MEDICINE AND SURGERY, FUDLIC PROFESSOR OF GENERAL AND OPHTHALMIC SCRGERY^ DIRECTOR OF THE CHIRURGICAL AND OPHTHALMIC CLINIC IN THE UNIVERSITY OF HEIDELBERG, &C. &C. &C. TRANSLATED FROM THE GERMAN, AND ACCOMPANIED WITH ADDITIONAL NOTES AND OBSERVATIONS, BY JOHN P. SOUTH, LATE PROFBSSOR OF SURGERY TO THE ROYAL COLLEGE OF SURGEONS OF ENGLAND, AND ONE OF THE SURGEONS TO ST. THOMAS'S HOSPITAL. IN THREE VOLUMES. PHILADELPHIA; LEA & B.L AN CHARD, 1847, Entered according to the Act of Congress, in the year 1847, by Lea & Blanchard, in the Clerk's Office of the District Court of the Eastern District of Pennsylvania. Wo / a 4-•)<>. v. 2> Griggs & Co., Printers. THIRD DIVISION. DISEASES DEPENDENT ON UNNATURAL COHERENCE. First Section—ON UNNATURAL COHERENCE IN GENERAL. 1550. The unnatural coherence of organic parts consists either in the union of neighbouring parts, which naturally are distinct; or in the for- mation of bad scars which diminish or destroy the movements of parts, by preventing their extensibility; or in a narrowing or closing of their outlets, by which their functions are considerably disturbed or rendered quite impossible. They are specially either consequences of previous inflammation, or vices of the original formation and congenital. 1551. In order that parts, which in their natural state are distinct, should unite together, a proper degree of inflammation, destruction of the skin, and long continued close contact are required. The union is either immediate, by means of a scarcely perceptible, interposed layer of plastic lymph, into which the vessels shoot; or it is fleshy, and depending on the development of granulations, and the formation of an intermediate substance, oftentimes having perfect resemblance to the parts it connects; or the connecting interposed matter is fibrous, membranous, in which case it would seem that there had been previously a more intimate con- nexion, which, in consequence of the movements of the connected organs, had formed these membranous lengthenings. For example, in the band- like adhesions between the peritonceum and the surface of the intestines, between the pulmonary and costal pleura. All organs are, under the above-mentioned conditions, capable of union; the serous structures and synovial membranes are most prone to it, the mucous membranes least so, and only when their surface is destroyed, and the underlying cellular tissue laid bare. 1552. When in a wound accompanied with loss of substance, especially in a severe burn, the treatment has not been conducted with due care, and the parts kept in proper position, the edges of the skin either greatly contract towards the centre, and a tough cord-like scar often connected with the underlying parts, or a superficial, prominent, knotty, misshapen scar is produced. In consequence of this the position and movements of the part are in various ways damaged or completely destroyed, or great de- formity is produced. It must not however be forgotten,*that in long continued unnatural position of a part, consequent on a scar formed in one of these ways, secondary contraction of the muscles, and alterations in the joints may be produced, by which the movements are still farther restricted; and this condition may even become incurable. 1553. All the outlets are peculiarly constituted. They are either furnished with a true muscular apparatus, or at least are endowed with a special contractility, upon which their alternate expansion and con- traction depend. Their inner surface is always overspread with mucous Vol. hi.—2 14 UNNATURAL COHERENCE membrane, in consequence of which they can, exclusive of the cases from compression by neighbouring swellings and the like, be narrowed or closed in a variety of ways: thus, first, by spasmodic contraction, sometimes transient, sometimes continued ; second, by hypertrophy, thick- ening and swelling of the parenchyma of the mucous tissue lining the outlet, consequent on previous inflammation, and on an unnatural vege- tative process; third, by actual growing together, when for instance the mucous membrane of the outlet is destroyed; and, fourth, by scars which form at the edge of the outlet, or in its neighbourhood. 1554. The congenital closure of outlets, {Atresia, Imperforatio,) as well as the congenilal union of parts, which should be separate Irom each other, {Synechia,) are arrested formations, in which the foetus, at an early stage of its development, remains stationary, when the openings and clefts on the outer surface of the body do not yet exist, and parts which at a later period become separate, are still united together. The skin' originally overspreads the whole surface of the body, and has on the parts where it closes the openings and clefts, the same character as elsewhere; it thins gradually, appears then as a peculiar secreting membrane, and is lastly removed by the process of absorption. As the Mresice are in the earlier stages of development of the foetus, natural formations, so also are the Synechice; for instance, union of the eyelids with each other and with the eyeball; the union of the tongue, of the glans penis with the prepuce, and the like. 1555. If the closure of the outlets be a vicious primary formation, either the organization of the outlet is natural, and its opening only closed by a mere skin, though sometimes by a tough fleshy mass, or no trace of an outlet can be perceived externally. When the congenital closure of . an outlet by which matters pass exists, it shows itself soon after birth, as in closure of the anus, urethra, and the like ; but if it occur in those which only at a later period assume the peculiar condition of outlets, as, for example, the vagina, the closure is generally then first observable. 1556. The treatment of union of parts, which in the natural state are free and moveable, requires division with the knife, together with the prevention of reunion, and all contact of the divided parts, by careful insertion of folds of linen, or lint besmeared with mild, and afterwards with drying ointments. The parts must also at the same time be kept in proper position, and during the period of granulation prevented by due application of caustic, from coining to that state in which they can again unite from the angle of the division ; for which purpose, usually, pressure properly employed, is most efficient. 1557. In shapeless scars, which, by contracting parts, interfere with their position and movement, only in rare cases can any considerable relaxation be effected by the continued use of softening ointments, baths and the like; usually, by operation alone can improvement or perfect cure be effected ; the management of which is different according to the condition and seat of the scar. If the scar be cord-like, tense, and by its shortness destroy motion, several transverse cuts may be made throu£>h its whole mass, and afterwards an apparatus put on, by which the parts shall be retained in natural posture, so that the formation of a broad scar may be effected. When the scar is broad, or united with the underlying IN GENERAL. 15 parts, so however that its release is possible without injury to important parts, it must be cut out. The scar must be included between two cuts, and separated by careful dissection from the parts beneath, or the cellu- lar membrane. If the skin in the neighbourhood of the wound be yield- ing, the edges of the wound, if it be not of very great extent, must be set free so far, that they may be united with the interrupted, or with the twisted suture. Although the edges of the wound«be thus much stretched, and the skin also in the subsequent healing be still so, yet in a short time it yields, and all deformity disappears. When, as is commonly the case, this union is impossible, the wound must be treated as one suppurating, and retained by a proper apparatus in its straight posture. For the pur- pose of making the scar sufficiently broad, frequent touching with lunar caustic must be resorted to. I have, however, always found that, in consequence, correspondent condition of the scar is produced, that is, the tough, knotty projection can be prevented; but the special contrac- tion of the edges of the skin towards the centre is encouraged. In all cases, therefore, in which I wish to form a broad scar, I only cover the suppurating parts with softening poultices or washes, and but rarely use caustic. When the scarring goes on- tediously, there is always least disposition to contract, and the easier is it to produce a broad scar. If the scar project in knots and thereby be disfiguring, it must either be removed with the knife held flat, from its base, and the wound healed up in the usual wTay; or it must be cut completely out, and treated ac- cording to circumstances, after the above-mentioned rules. On the different modes of treating deformed scars, compare Beck ; in Heidelb. klinisch. Annalen, vol. v. p. 213. Dupuytren; in his Lecons Orales de Clinique Chirurg., vol. ii. p. 1. 1558. The narrowing and closure of the outlets require, according to their several causes, a different treatment. In spasmodic contraction, both local and general, corresponding antispasmodic remedies must be employed. If the narrowing result from an organic change of the mucous membrane, it must be specially ascertained whether, and what is the cause of the inflammation, which must be met with corresponding treatment. Should this, however, not be sufficient to get rid of the nar- rowing, the employment of mechanical means, which gradually widen the outlet, is required; or the removal of the hardened part of the mucous membrane must be attempted with the knife, with caustic, and the like. In these various modes of treatment, it must always be remembered, that should the natural calibre of the outlet be restored, the mucous mem- brane has always a peculiar disposition to reproduce tue narrowing. 1559. The cure of imperforation is more or less difficult, in proportion as the seat of the closure is more or less deep, and depends on a mem- brane, or a fleshy mass. The closed part must be cut into, and its reunion prevented by the introduction of mechanical bodies. In closure of an outlet by membrane, if the latter be thrust down, in a flask-like form, by the collection of the excreted matters, the division is easy, and the skin must be divided with a crucial cut. But if the union be inti- mate and fleshy, the division is more difficult, and so much more so, in proportion to the greatness of its extent; it must always be made in the middle line of the union. If there be scarce any trace of the external opening of the outlet, the cut must be made in the direction in which it should open, and the outlet there sought for. [ 16 ] Second Section—OF UNNATURAL COHERENCE IN PARTICULAR. I.—OF THE UNION OF THE FINGERS AND OF THE TOES. Earle, Henry, On Contractions after Burns or extensive Ulcerations; in Med. Chir. Trans., vol. v. ----Further Observations on Contractions succeeding to ulceration of the Skin, in Med. Chir. Trans., vol. vii. Beck, K. J., Ueber die angeborne Verwachsungder Finger. Freiburg, 1819. 8vo. Seerig, Ueber die angeborne Verwachsung der Finger und Zehen, und Ueberzahl derselben. Breslau. 4to; with two lithographed plates. 1560. The union of the fingers with each other has different degrees of intensity and extent, and is either congenital or accidental, especially after burning the fingers. The congenital union arises, first, from bridges of skin ; second, from connexions of skin and flesh ; and, third, from run- ning together of bone. The first kind of union is the most frequent. The natural formation of the finger may also be variously degenerated in these unions. 1561. The single mode of getting rid of these deformities consists, in dividing the union, which is alone contra-indicated, when the soft parts of the hand are grown together in an unshapely mass (1), and the bones of the fingers so run together, that there is scarcely any connexion by joints; Diseased condition of the skinny covering of the ill-formed hand, a highly scrofulous condition of the constitution, still existing in- flammation, or great plastic activity, and the age of the party, may render the delay of an operation requisite. The time generally considered most suitable for operation, is the end of the first year of the child's life, and beyond that time, except for very special reasons, it should not be de- ferred. The fact, however, that even after the operation-wound has been perfectly healed, the fingers will again grow together, which depends partly on the deficiency of the skin, and its production not corresponding with the formation and growth of the finger, partly on the incompletely divided union stretching on with the enlargement of the finger is of the greatest importance, and must, if the union of growth do not prevent seem most properly to put off the operation, till the complete develop- ment of the finger {a). The painfulness of the operation, as well as the ensuing inflammatory reaction, depend on the degree and extent of the union, on which account only one hand should be operated on at once and the other at a more distant time. (1) In a case in which the hands of a child presented only two lumps of flesh with a single undivided nail, five moveable fingers were made, by cutting through the common cartilaginous mass {b). s 1562. The result of the operation is often unsatisfactory, as reunion of the divided parts will occur, under the most careful treatment. This is to be especially feared at that period when the granulations rise from the hinder angle of the wound, and the edges of the wound draw together from both sides. To prevent this, various modes of operation have been proposed. (a) Seerig, above cited. (6) Leroux ; Journal de Med., vol. xiv. p. 275 TREATMENT OF UNITED FINGERS. 17 1563. In a simple, merely skinny union, after properly fixing the hand, a pointed bistoury is thrust, either with its edge towards the operator, somewhat above the angle of the natural junction of the fingers, verti- cally, through the connecting skin, and then divides it in the mesial line to the finger-tips; or the knife is carried from the points of the fingers backwards through the connexion. The irregularities of the edges of the wound are to be trimmed with the scissors. If the bones be also connected, the soft parts must be first divided with the bistoury, and afterwards the bony union, through the mesial line, with a little watch- spring saw. The dressings must be most carefully applied: a strip of linen, spread, at its ends only, with adhesive plaster, must be placed in the angle of the wound, and the two ends respectively fixed on the front and back of the hand. Over this a small long pad is placed, the surface of the wound covered with some folds of linen, spread with ointment, each several finger enveloped in a bandage, and the finger, by means of a piece of card-board or wood attached to the hand, kept as straight as possible ; this may also be effected by particular contrivances (a). The dressing should be daily and very cautiously renewed once or under particular circumstances even twice, with strips of linen laid close in the angle of the wound; and towards the end of the cure, by a moderate application of caustic, the growth of the granulations there must be repressed. Dupuytren (&) applied a narrow long pad with its middle on the angle of the wound, carried with its ends to the fore-arm, and fastened them to an arm-bandage. He could not, however, by these means prevent the reunion. And he did not suc- ceed any better with'a narrow strap which he buckled to the arm-bandage. 1564. To prevent the reunion of the angle of the wound, which espe- cially in firm union, is to be dreaded, Rudtorffeb, (c) thrusts a steel needle fourteen lines in length, the point of which is lancet-shaped, and its other end having a hole, for the reception of a leaden thread two inches long, vertically between the two united fingers, and thus intro- ducing the leaden thread, bends and leaves it there. Cold water checks the bleeding and pain, and the sticking of the leaden thread is diminished by smearing the edges of the wound with oil. The thread is to be fre- quently moved, and the drying up and scarring hastened by use of lead wash. Beck {d) uses a lancet-needle ten lines broad with a leaden thread of equal width, w7hich is left for some time, till the scarring of the edges of the wound. The leaden thread has a decided preference to the leaden plate, as by fixing its turned ends, pressure is always kept up against the angle of the wound, for with the leaden plate, with which this cannot be done, the growth at the angle of the wound goes on, and the lead is thrust out, as I saw in one instance. 1565. If the skin upon the back of the united fingers be sound and natural, it should be divided, according to Zeller(c), a little beyond the (a) Zang ; Darstellung, u. s. w., vol. iv. pi. Theil der Wundarzneikunst sich bezienden iii. Beobachtungen, vol. ii. p. 478. (6) Legons Orales, vol. ii. p. 36. (d) Above cited. (c) Abhandlung ilber die einfachste und (e) Abhandlung fiber die ersten Erschein- sicherste Operationsmethode ein gesperrter ungen venerischer Local-krankheitsformen, Leisten und Schenkelbruche; nebst einem p. 109. Wien, 1810. Anhange merkwurdiger, auf den operativen 18 GROWING TOGETHER second phalanx ; a V-shaped cut should then be made in the skin on the dorsal surface, with its point on the middle of the connecting substance. The skin should be detached, turned back, and, after the complete division of the union, this flap should be carried down between the fingers towards the palm, and fixed with sticking plaster. This treat- ment is rarely possible, as the skin is most commonly hard, callous, morbidly changed, and the flap commonly dies (a). Krimber {b) has, however, given some satisfactory reports of this operation. 1566. If the reunion of the fingers cannot be prevented, the operation mustjDe repeated, but the inflammatory reaction and plastic activity must have completely subsided. II.—OF GROWING TOGETHER OF THE JOINT ENDS OF BONES, OR ANCHYLOSIS (c). Muller, Diss, de Anchylosi. Lugd. Batav., 1707. Van Doeveren, Diss, de Anchylosi. Lugd. Batav., 1783. Murray, Diss, de Anchylosi. Upsal, 1787. Delpech, Precis Elementaire, vol. i. Barton, On the Treatment of Anchylosis, etc. Philadelphia, 1827. Lacroix, De l'Anchylose ; in Annales de l'Anatomie et de la Physiologie patholo- giques, publ. par Pigne, 1843. 1567. Every intimate union of two bones, which naturally are con- nected together in a joint, produces complete loss of motion in the joint {Anchylosis, Lat. ; Gelenksteifigheit, Germ.; Ankylose, Fr.) Anchylosis is commonly divided into true and false. Under the former, is com- prehended the loss of motion in a joint, depending on the union of the Joint-surfaces; under the latter, that condition, in which the movements of the joint are only more or less interfered with, as is observed in long-continued inflammation of joints, in swellings of the ligaments, in tumours near the joints, in continued contraction of the muscles, and the like. This division is, to a certain extent, incorrect and objec- tionable, because, in the so-called false anchylosis, the hindrance of motion is only to be considered as a symptom of the disease, towards the removal of which the plan of treatment must be directed, and the union of the joint-ends of the bones is alone to be considered as the actual disease. 1568. The growing together of the joint-surfaces may be produced in various ways. It is usually consequent on inflammation of the parts composing the joint, especially when of some standing, and when the joint has been long at rest. If the inflammation go on to suppuration and the cartilaginous surfaces be destroyed, if there be carious destruc- tion of the bones, granulations may form, which, by shooting into each other, may become the means of union. Long-continued immobility of a joint may also cause an union of the surfaces. Although this is very rare, and may be readily distinguished, from the restrained motion which is consequent on habitual contraction of the muscles, on swelling of the ligaments and the like, observed after dislocation, and after the treatment (a) Walther, Ph. F., Ueber die ange- (c) All the additions which seemed to m bornen Fetthautgeschwiilste, p. 32. Land- necessary, have been already made at d 2fi7G schut, 1814, fol. vol. i., in treating of Anchylosis as a termi' (b) Graefe und Walther's Journal, vol. nation of joint disease.—j. f. s. xiii. p. 602. OF THE ENDS OF BONES. 19 of fractures, and may be got rid of by motion, softening rubbings, and so on, it is, however indisputable ; although the ordinary explanation given of it, from want of synovia, or comparison of it with the obliteration of blood vessels, when the circulation is suppressed, is insufficient (a). 1569. According to the sort of union of the joint-surfaces produced, and its duration, is the nature of the connecting substance. It is either soft and yielding, frequently lengthening into ligament-like bands, or it is converted into an actual bony mass by the deposition of phosphate of lime. 1570. The treatment of anchylosis must be determined by the follow- ing circumstances. In most cases where anchylosis takes place, it is a desirable result, for example, in caries of joints, the so-called white swelling, and the like; and it should by no means be sought to prevent it, for all the attempts made with that object will only increase the in- flammation, and the danger of the anchylosis. In such cases there- fore, the joint must be kept in the most perfect rest, and in such position, that the anchylosis ensuing will be most convenient and advantageous. Subsequently, when the inflammatory symptoms have disappeared, three conditions are possible; the substance connecting the joint-surfaces is either yielding, and by continued and gradually increased movements of the joint, may be lengthened into ligament-like bands, or these mo- tions may reproduce the inflammatory symptoms, or they may be very difficult and become every day more and more confined. In the first case the movements are always accompanied with pain, which must be got rid of by emollient and soothing applications, rubbing in, bathing, and the like, and motion not carried to such extent as would produce fresh inflammation of the joint. In the second case, all motion must be avoided; and in the third, no effort can be in the least useful, because the mass has been already more or less converted into bone. J. Rhea Barton (6) sawed through the thigh-bone at the trochanter, in a case of anchylosis at the hip-joint, brought the limb into proper position, and by motion pre- vented union. He also employs this practice on other joints. It is only practicable when the patient is in good health, and when the stiffness depends on the soldering together of the bones, the soft parts at the same time being unaffected with disease, and all the muscles and tendons which contribute to the motions of the joint healthy; when the cause of the disease is entirely removed ; when the operation can be per- formed so close to the original point of motion, or so near to it that the functions of the greater number of muscles and tendons can be preserved; and when the defor- mity and inconvenience is so great, that the patient is induced to subject himself to the pain and danger of such an operation, von Wattmann has obtained a favoura- ble result by sawing through the upper-arm bone in anchylosis of the elbow joint. Dief enbach (c) believes that the separation of the united joint by means of the chisel and saw, would not be more hurtful than the above-mentioned sawing through of the bone, to form an artificial joint, inasmuch as the anchylosed joint is no longer a joint, and therefore wounding it is not to be so much dreaded. 1571. The slighter degrees of the so-called false anchylosis depending on contraction of the muscles or ligaments, or on contracting scars, may be completely moved by rubbing in suppling ointments, by relax- ing baths, steam and the like, with the simultaneous use of apparatus (a) Delpech ; above cited, p. 611. American Med. and Surg. Journal, vol. iii. (6) On the Treatment of Anchylosis by p. 279. 1827. the Formation of Artificial Joints; in North (c) Ueber die Durchschneidung der Schnen und Muskeln, p. 249. 20 GROWING TOGETHER OF BONES, (1), which gradually straightens the joint. In the more severe forms of contraction little or nothing is effected in this way; in such cases violent and sudden extension; gradual extension with an apparatus, the tendons having been previously divided; or, sudden and violent ex- tension soon after cutting through the tendons, have been proposed and practised. The first mode of treatment (Louvrier's) is objectionable (2); the extension, by apparatus, after division of the tendons is gene- rally tedious, must be very long continued, often produces considerable pain, and frequently meets with invincible obstacles; with it, however, no dangerous symptoms are to be feared. The violent extension after division of the tendons will considerably shorten the cure (Dieffenbach.) This mode of treatment especially applies to the false anchylosis of the knee; it may, however, be employed in other joints. (1) Of the various apparatus for extending the knee-joint (Stromeyer, Duval, Bouvier, and others) I think Stretter's the most preferable. (2) According to Beraro, (a) of twenty-two cases of false anchylosis, treated by Louvrier's method, three were fatal, on account of the severity of the violence; in neither was a well-formed joint produced; in the greater number there was disloca- tion of the knee backwards, and always renewed though slight contraction. 1572. In contractions of the knee-joint the patient is laid on his belly, that the crooked knee may project beyond the edge of the table. The tendons, having been rendered very tort by violently pulling the leg, are cut through beneath the skin and the limb bent so strongly that the heel shall touch the buttock. It is then again forcibly extend- ed, and again flexed, and this backward and forward motion is con- tinued till the limb is straightened. Sometimes there is a loud crack, from the false connections being thus torn through. In grown persons it often requires the united strength of three or four men, to break the knee-joint perfectly straight. Even in a case of true anchylosis, con- sequent on a penetrating wound of the joint, and its resulting suppura- tion, the breaking through of the united knee-joint, and the straight- ening of the limb, is required (Dieffenbach.) Immediately after the extension of the limb is effected, the knee-joint should be covered with pads, enveloped in a flannel roller, laid upon a padded hollow splint, and the splint and limb fastened together with a second flannel bandage. On reapplying the apparatus, the limb must be carefully cleansed, and in replacing it, much local pressure must be avoided, or slough of the skin will quickly ensue. After completion of the cure, the straight stiff joint must be carefully bathed and rubbed with suet. In manv in- stances, if the joint again become flexible, the patient may be able to walk without halting (Dieffenbach.) 1573. Very severe symptoms may result from this violent extension of the limb, great inflammation, with its consequences may ensue, so as to render amputation necessary, and may even cause death. These emergencies, as well as the more or less favourable result of the opera- tion rests, independent of the constitution of the patient, especiallv on the changes which have occured in the ioint itself and in the neigh- bouring parts. In contractions already long existing, and accompanied with great alteration of the joint, there is always "a dislocation of the leg upon the thigh, from within outwards, or from without inwards • (a) Gazette Medicale de Paris, vol. ix. p. 324. Paris, 1841. AND OF THE NOSTRILS. 21 the shin-bone often gets under the thigh bone, so that the foot is short- ened, the knee-cap very prominent, and the ham Jess hollow; the condyle of the thigh bone is often curved backwards, the whole limb wasted and atrophic. In such cases little violence is needed to dislo- cate the leg backwards. Even when by such alteration of the joint, the straight posture is effected, it has a most imperfect result, as the joint always remains more or less bent) the leg more or less placed behind the thigh, and the patient is only able to go on a crutch. In long-continued contraction of the knee-joint, the popliteal artery may be so considerably shortened, that extension of the limb cannot be effected without tearing it. (Chassaignac.) The splint-bone may be also so fast connected with one or other condyle of the thigh, or may be so thrust in between the shin-and thigh-bone, as to render the straighten- ing of the limb impossible. If the contraction of the joint be only con- sequent on a change of the surrounding parts, the result of the operation will be more favourable, as the joint will resume its natural form, power, and motion. In this case the joint is always more moveable in the flexing direction. Great crookedness of the knee-joint often cannot be rendered straight after cutting4he tendons; it will always crook again. The cause is, in this case, in the shortness of the lateral ligaments, usually in the external one, which is stretched under the skin, and must be cut through beneath it {a). III.—OF THE GROWING TOGETHER AND NARROWING OF THE NOSTRILS. 1574. A complete closing up of the nostrils is more rare than their narrowing, and is commonly the result of ulceration and burns; it is rarely congenital. In slight narrowing, the malformation is inconsider- able, and usually requires no assistance. In more considerable narrow- ing, or growing together, the breathing is affected, especially at night, and the speech also. The connexion may be either at the edges of the nostrils, or the wings of the nose may adhere to its septum, and the growing together may extend more or less into its cavities. By the projection of the air in blowing through the nose, with the nostrils still open, the extent of the connexion may perhaps be ascertained. 1575. When the nostrils are merely narrowed, after an assistant has fixed the patient's head, a director is to be introduced into the nostril, and upon it a narrow straight bistoury, with which the narrowed part is to be cut through according to the form and direction of the nostrih which is thus widened. If the nostril be closed by a mere skin, this must be pierced with a bistoury, and its edges, having been taken hold of with forceps, raised and cut off. If the nostril be completely grown together, the bistoury must be thrust in the direction where the cavity should be, till it reach it, and being then withdrawn, and a director in- troduced, the bistoury is to be carried in upon it, and the connexion divided, as above described. This operation is always more doubtful, and its consequences less certain, the higher the connexion extends. 1576. After the division, the natural calibre of the nostril must be (a) Phillips, Ch., De la Tenotomie souscutance, c, p. 114. Paris, 1841. 8vo. Vol. hi.—3 22 OF UNNATURAL ADHERENCE OF THE TONGUE. preserved by dressing, which is managed by introducing plugs of lint, 6r a quill wrapped with lint, by gum-elastic tubes, or Benjamin Bell's little tubes {a) smeared with lead ointment, and kept in position by a bandage round the head. The dressing must be renewed daily, all fo- reign matters removed, the nose cleaned, and after injection of lead wash, reapplied. If the introduced hard substances produce much ir- ritation, plugs of lint must be used instead. This treatment must be continued till the opening of the nostril be completely skinned over, and even still longer, if we desire to avoid all disposition to a recurrence of the growing together or narrowing. When such disposition is noticed, it must be opposed by the use of expanders, sponge-tent and the like. On account of the great disposition to repeated closure, the operation must never be undertaken whilst the plasticity is still very active. When the narrowing of the nostril depends on unnatural formation of the bones, no expansion can be effected. IV.—OF UNNATURAL ADHERENCE OF THE TONGUE. Petit; in Memoires de l'Academie des Sciences. 1742. Louis, Sur les Tumeurs Sublinguals; in Mem. de l'Acad. de Chir., vol. v. p. 410. Oehme, De Morbis recens-natorum chirurgicis. Lipsiae, 1773. Lang, De Frenulo linguae, ej usque incisione. Jenae, 1785. 1577. An unnatural adherence of the tongue, by which sucking, the movements of the tongue, and proper articulation of the voice, are more or less prevented, may depend, first, on a tough, fleshy swelling of a brownish colour, and often nearly of the same size with the tongue, be- neath which it lies; second, on the tongue-string {frcmulum,) which either extends to the tip of the tongue, or is too short, {tongue-tied of common language, j. f. s.); third, on membranous connexions of the tongue on one or both sides; fourth, on union of the under surface of the tongue with the corresponding surface of the mouth. The diagnosis of these conditions rests on examination. In children by holding the nose, the mouth is made to open, and then with two fingers the tongue is raised and pressed towards the palate and sides. The examination is more necessary, as in many cases, the inability of children to suck from their mother and wet-nurse is ascribed to the tying of the tongue, whilst it really depends on other causes. 1578. When by this unnatural attachment of the tono-ue suckino- is prevented, or at a later period the speech is interfered with' the tongue must be set loose that it may enjoy free motion. 1579. In cases where the above-mentioned tumour is observed under the tongue, speedy assistance is always needed, which consists in cutting into the swelling. An assistant holds the child's nose, forcibly lifts up the tongue with the thumb and forefinger of the left hand, with its palm upwards, by which the fleshy mass is made more tense, and then it is cut into with a pair of blunt-pointed scissors. The wound generally heals in a few days, the spittle and milk render any topical application useless and it is necessary to move the finger under the tongue frequently during (a) System of Surgery, vol. iv. p. 88. 1786. OF UNNATURAL ADHERENCE OF THE TONGUE. 23 the day, in order to prevent the reunion. In some cases it is advisable to scarify the tumour with a lancet, to diminish its size and give the tongue free motion. If the ranine artery or vein be wounded, it must be treated as already mentioned. 1580. The division of the tongue-string either when too short, or when reaching the tip of the organ, must be effected after properly raising the tongue, as in the former case, with the two fingers of the left hand, or with a spatula having a cleft in it for receiving the tongue-string, and rendering it tense, by JSchmitt's tongue-scissors, which, with their con- vexity upwards, are carried to the fracenulum and cut through it, at a stroke, to the necessary extent. In doing this the scissors are directed as low as possible, towards the bottom of-»the mouth, to avoid injuring the ranine artery. The instruments referred to are Petit's spatula, with a snap-knife {a). Benj. Bell's scissors (i). Schmitt's scissors (c). 1581. When the tongue unites with the corresponding surface of the mouth, the child's mouth must be kept open by means of a piece of cork thrust between the jaws, and the tip of the tongue being raised with the fore and middle fingers of the left hand, the tongue must be set free with a curved bistoury to its proper extent. [Occasionally, though not, I believe, very often, after severe sloughing of the membrane of the mouth, mostly after the use of mercury, the tongue contracts ad- hesions with the cheek. I have recently had one such case under my care, the only one I have seen, in which the side of the tongue was attached to the extent of half an inch. I applied a ligature around the band, which separated in three or four days, and set the tongue free. I preferred the ligature to snipping it through, lest there might be trouble from after-bleeding.—j. f. s.] 1582. The accidents which may occur after separating the tongue in the above cases are bleeding, and when the tongue has been divided to a great extent there is danger of suffocation. Attempts to stop bleeding of the wounded ranine artery must be made with little bundles of lint, moistened in styptics, Theden's arquebusade, or a solution of alum, which should be pressed against it with the finger; or the actual cau- tery may be applied to the bleeding part, which in all cases is preferable to the compressors of Petit, Jourdain, and Lampe. Bleeding may also be produced by the child sucking his tongue; in which case the blood will be swallowed. Care must, therefore, be taken for the first few days, that when he awake he be laid on his breast. If there be danger of suffocation by the tongue turning backwards, it must be brought forward with the finger in the mouth, put in its place, and there kept by means of a thick pad put upon the tongue, and fas- tened by a bandage carried round the lower jaw; this must be removed as often as the child needs to drink {d). 1583. The membranous connexion of the tongue with the correspond- ing part of the gums, fixes the tongue either equally on both sides, or it is drawn to one or other side, according as it is unequally attached, or upon one side. The division of this connexion is always easily ef- fected with the scissors. (a) Above cited, fig. 1, 5, 6, 7. (c) Loder's Journal, vol. iv. part ii. pi. v. (b) Above cited, vol. iii. pi. xiii. f. 166. f. 1, 2. , (d) Petit. 24 OF NARROWING AND CLOSURE OF THE MOUTH. V.—OF GROWING TOGETHER OF THE GUMS AND CHEEKS. 1584. The growing together of the gums with the cheeks is mostly consequent on inflammation and excoriation, the violent use of mercury, and the severe salivation following it, if the lips and cheeks be quiet. It may be of greater or less extent, by which chewing and speech are more or less hindered. It may be prevented in the above instances by frequently cleansing and injecting the mouth, by pencilling it with mu- cilaginous fluids, by the introduction of pieces of soft linen, by frequent movements of the parts, and introduction of the fingers ; and, by the same means, an already formed aaglutination may be got rid of. If the con- nexion be firmer it must be divided with a bistoury, and prevented re- uniting. VI.—OF NARROWING AND CLOSURE OF THE MOUTH. Dieffenbach, Erfahrungen iiber die Wiederherstellung zerst6rterTheile,u. s. vr., sect. iii. p. 65. Rost, G., Diss, de chilo- et stomatoplastice. Berol., 1836. Baumgarten, Diss, de chiloplastice et stomatopoesi. Lips., 1837. Zeis, Handbuch der plastichen Chirurgie, p. 435. 1585. Complete closure of the mouth as a vice of the first formation, is very rare, and mostly accompanied with other vicious formations. A small opening must be first made in one or other corner of the mouth, whilst lifted up with the forceps; a director is then introduced, and upon it the closed membrane must be divided. 1586. Narrowing of the mouth frequently happens in consequence of large scars after the operation for cancer of the lip, or after any other wound with great loss of substance ; usually, however, the mouth ex- pands and the lips and cheeks retaining their extensibility, gradually allow its return to the ordinary form. But when there is a hard callous state of scar with simultaneous great loss of substance, and growing together of the membrane of the lips and cheeks with the gums, as after" burns, destroying ulcers in herpes rodens, but especially after excessive a*nd ill-employed use of mercury and the like, then such enlargement of the mouth will not follow, and three degrees of deformity may be dis- tinguished ; first, narrowing of the mouth from growing together of the internal surface of the cheeks and lips with the jaws,°in which the external lips are unconcerned; second, the growing too-ether of the mouth, and the conversion of the cleft of the mouth into a small round hole; third, destruction of the external lips with great loss of substance to a wide extent, so that the teeth are exposed, and the jaws cannot be separated from each other (Dieffenbach.) The inconvenience is various according to the degree of narrowing; the introduction of food and chewing, is more or less difficult; the patient often can take only liquids with trouble; the nourishment fails, tartar collects on the teeth • the smell of the breath is very offensive, and the like. 1587. Widening of the mouth by cutting at both corners, as formerly advised is useless, as the cut always again unites, and the deformity is worse. The treatment must vary according to the several degrees of narrowing and destruction of the lips. OF NARROWING AND CLOSURE OF THE MOUTH. 25 1588. If the lips, otherwise unhurt, be connected by thread-like adhe- sions to the jaw, that part of the lip where the union is greatest, must be strongly drawn down, the tough scar divided, and the adhesions throughout their whole extent properly removed with the knife or scis- sors, as far as possible, to allow the lower jaw to be depressed. The mouth is then to be well washed with cold water, and frequently widely opened, and the cure usually soon follows. But if the entire surfaces be grown together, a corresponding portion of the sound membrane of the mouth must be separated to the thickness of common paste-board, applied over that part of the cheek opposite the meeting of the teeth, and fastened with the interrupted suture, so as to prevent the reunion of the wounded surface by the museous membrane spread over it. When in these cases the breadth of the lips is narrowed by previous ulceration and proportionally shrivelled, no advantage will be derived by this operation, as they will always remain attached to the jaws. The en- largement, of the aperture of the mouth must also be effected in the way above mentioned. 1589. In considerable narrowing of the mouth from its growing to- gether and firm scarring, which mostly affects one or other corner of the mouth, or even both, Dieffenbach's {a) and Werneck's (6) modes of treatment are the best. A thick strip of the entire soft parts, down to the mucous membrane, which must be left uninjured, is to be cut from the mouth at one or both sides; for which purpose, the pointed blade of a pair of sharp scissors thrust into the corner of the mouth is carried to some extent between the soft parts of the cheek and the mu- cous membrane, and the cheek cut through to the part where the angle of the mouth is to be formed. From the lower corner of the mouth, a cut parallel to the- former is connected by a short circular cut. The piece of skin thus circumscribed, is now to be completely separated from the mucous membrane, and afterwards the other side similarly treated. When the bleeding is stanched, the lower jaw must be much depressed, by which the exposed mucous membrane will be considera- bly stretched, and must then be separated for a few lines from the mem- brane of the cheek, and divided in the middle, but not so far as the corner of the mouth. After stanching the blood and closing the wound, the mucous membrane must be drawn out over its edges, and the edges of the membrane connected around with fine needles and the twisted suture. The mucous membrane folds opposite the middle of the lip which has not been disturbed. The part of"the mucous membrane not cut through should be well drawn out at the corners. The bloodless expansion of the mouth with sponge-tent, and the like, is useless. Horizontal cuts on either side, as formerly recommended for widening the mouth, are unavailing, inasmuch as they always re-unite, and the person's condition is worse. The practice of Kruger-Hansen (c), wh'o, after Rudtorffer's statement in reference to united fingers, (par. 1555,) made an opening with a trocar into a mouth half closed by a callous scar, at the point where its boundary was to be fixed, in which he allowed a leaden thread to remain till the part had skinned over^ after (a) Rust's Magazin, vol. xxv. p. 383, and tfier's Journal, vol. iv. p. 202. His mode work above cited, p. 44. of treatment is similar to Dieffenbach's, (6) Uber die ktlnsiliche Mundwinkel- und but published subsequently. Lippenbildung durch blutige Umschlagung (.c) von Graeje und Walther.'s< Journal, der Mundhaut; in von Graefe. und Wal vol. iv. p. 543. 3* 26 STRICTURE OF THE which the remaining cut was made, is tedious, uncertain, and produces a callous aperture for the mouth. 1590. If with narrowing of the mouth there be such loss of substance in the lips, that the teeth are exposed, and the jaws cannot be separated from each other, and in which often the small opening of the mouth is dragged upon the cheek, the deformity can be only somewhat improved, and the patient's condition alleviated, after careful examination of the peculiarity of the case, by cutting out the hard scar, loosening the at- tachment to the jaws, drawing over the skin, and the like. Compare also an interesting case of a similar operation of Dieffenbach's (a). VII—OF NARROWING OF THE CESOPHAGUS. Bletjlano, Observationes anatomico-medicae de sana et morbosa Oesophagi struc- tura. Lugd. Batav., 1769. Von Geuns, M., in Verhandelingen uytgegeeven door Holl. Maatschappy der Wetenschappen, vol. xi. Haarlem, 1769. Kunze, A. G., Commentatio pathologica de Dysphagia. Lips., 1820. Home, Everard, Practical Observations on the Treatment of Strictures in the Urethra and Oesophagus, vol. i. p. 536. London, 1805; Third Edition, vol. i. p. 395; Second Edition, London, 1821. Fletcher, Robert, Medico-Chirurgical Notes and Illustrations on some danger- ous affections of the Throat; on Strictures of the GSsophagus, &c. Lond., 1831. 4to. Mondiere ; in Archives generates de Medecine, vol. xxv. p. 58. -1831. Appia, Dissert, de Stricturis Oesophagi. Heidelbergae, 1842. Chelius, Ueber die Behandlung der Stricturen des 03sophagus; in Heidelberg. JVIedic. Annal., vol. i. pt. ii. [Watson, John, On Organic Obstructions of the Oesophagus; in the Amer. Journ. of the Med. Sciences, vol. 8., N. S. 1844.—g. w. n.] 1591. Narrowing of the oesophagus may be produced by various causes; by scars after wounds or burns {par. 474;) by the swelling up of its walls consequent on chronic inflammation of its internal coat; by scirrhous or callous hardening; by fungous, polypous, or warty growths; by a vari- cose condition of the vessels; by tumours, especially swellings of the glands which compress the oesophagus; and by spasm. Hoederer (b) observed an cesopkagus with a blind end in a monster. The same was also seen in a full-grown and otherwise well-formed child (c). 1592. The consequence of narrowing of the oesophagus is more or less interference with swallowing; the symptoms, however, vary according to the kind and seat of the narrowing. 1593. In simple {membranous) stricture, which, resembling a fold of the internal membrane of the oesophagus, occupies only a small extent and is usually situated at the upper part of the tube, opposite the cricoid cartilage, the patient first feels, at one particular spot, a slight difficulty in swallowing solid food, and, when the food passes over the part often a shivering in the back. This difficulty continues a longer or a shorter time, diminishes or ceases, and reappears without any particular cause or after a chilliness, mental emotion, and the like. The disease may thus long continue getting better and worse. Earlier or later the diffi- (a) Erfahrungen, sect. iii. p. 110. (c) Hari.ess, Rheinisch. Jahrbuchern der (6) Commentar. Societ. Goettirag, vol. iv. Med. und Chir.., vol. i, pt. 2. CESOPHAGUS. 27 culty in swallowing becomes greater, large pieces of food will be retained at that particular part of the oesophagus, in consequence of which, symp- toms of choking, with the sensation of a violent, spasmodic contraction of the neck, cough, and great straining are produced, by which the food, frequently with an audible grating noise, passes over the obstacle, or by the contraction of the walls of the oesophagus, and the straining of the patient, is returned to the mouth, and thrown out. The difficulty in swallowing is now constant, and increases more slowly or quickly, so that the patient can swallow less and less food, with the above-mentioned symptoms; at last can swallow it no longer, and is reduced to the use of thin broths and fluids, in the swallowing of which even, the same symp- toms come on. Even when the difficulty in swallowing is constant, there is often, from time to time, a little improvement, for which, however, as well as for the subsequent aggravation, no reason can be assigned, if ac- companying spasmodic affection be not assumed. With the increased difficulty of swallowing, the patient's nourishment is affected; he wastes to the most extreme degree, and is starved to death. In this form of stricture of the oesophagus, there is, however, no farther appearance of any specific morbid reaction. 1594. The change by which the internal membrane of the oesophagus causes this narrowing, in which it forms a fold-like projection, capable of contracting itself to the smallest aperture, generally depends on an in- flammatory condition of the mucous membrane of the oesophagus; fre- quently, however, no decided cause can be found ; oftentimes it occurs after a cold. At the beginning, the disease, on account of its getting alternately better and worse, is thought to be a spasmodic affection; it is, however, probable that a spasmodic affection may pass into permanent stricture. This form of narrowing of the oesophagus occurs more fre- quently in mid-life, and, according to my experience, more frequently in women than in men; I have, however, noticed it in persons of fifty or sixty years of age. Home (a) has given a beautiful engraving of a membranous stricture. 1595. The callous narrowing of the oesophagus mostly consists of a circular thickening of the walls of the tube, at a particular spot; it may, however, be variously spread, often only one or other wall of the oeso- phagus is affected to a different extent. It is generally, from the first, accompanied with great inconvenience; the food, at the moment of swal- lowing, causes violent pain, mostly between the shoulder-blades; it is thrown up, and commonly also with it a morbidly large quantity of tough mucus, secreted from the almost entirely closed breathing passages. The patient assists himself by throwing himself back, stretching out his neck, and similar movements, in order to carry the food over the seat of nar- rowing ; oftentimes the food passes on with a noise and cessation of pain ; afterwards every portion of food is returned, with a gurgling noise and violent cough. This disease also for a time yields, and usually makes slow progress; I have, however, seen in one case the patient starved to death in three months, and on examination a circular, regularly callous thickening of the walls of the oesophagus was found at its upper part, and gradually lost itself both above and below. (a) Above cited, p. 422. 28 STRICTURE OF THE 1596. In scirrhous hardening of the walls of the oesophagus, which otherwise in its symptoms has great resemblance to the callous condition, and is generally situated at the lower part of the asophagus, and even at the cardia, the difficulty in swallowing usually increases slowly, and the patient has also a dull, weighty, dragging, and often very painful sensa- tion at the part, especially opposite the spine, which diminishes on lying down. 1597. The symptoms and accidents in this stricture of the oesophagus, are especially different in reference to its seat and extent, and particularly as regards the condition of the oesophagus above the stricture; as when, as is frequently the case, it is considerably expanded, the food that is swallowed, collects in great quantity, and is only afterwards thrown up. The expansion of the walls of the oesophagus is either of the whole of the canal, or only partial, and depends on the protrusion of the internal coat between the separated fibres of the muscular coat, so that a sac of various size is formed (Diverticulum, Hernia (Esophagi, (Esophagus succenturialus, &c.) This partial expansion occurs also frequently without any narrowing of the oesophagus,■ at least, I have never ob- served it with, but twice without stricture. It depends on the excessive expansion or tearing of some muscular fibres in the swallowing, and sticking of large, hard pieces of food, and the like. The food gets into this sac, expands it still more, and sooner or later, without any straining, is thrown up into the mouth. Whilst eating, the patient, when this sac is full and at the upper part of the oesophagus, must, as I have witnessed, empty it, from time to time, by pressure with the fingers, so that he may be able to swallow better. 1598. In the scirrhous and callous, cartilaginous and bony, narrowing of the oesophagus, which occurs, specially after the abuse of spirituous liquors, from the habit of eating and drinking very hot things, from the suppression of the ordinary discharges, from the venereal disease and alike, generally in advanced age, and in men, ulceration comes on at the later period, by which part of the stricture is destroyed, and symptoms of hectic consumption ensue. When these strictures are of long con- tinuance, the ulceration always begins on the side next the stomach, which must be attributed indeed to the frequent efforts to vomit, by which the walls of the oesophagus below the stricture are deprived of their na- tural activity and natural moisture. The ulceration is usually seated on the hind wall of the oesophagus next the spine, and not unfrequently at- tacks the bones; it may, however, destroy the front wall and the corre- sponding part of the trachea or^bronchi, and a communication may be produced between them, in which case most violent cough, choking on every attempt to swallow, and haemorrhage are produced. I have seen one case of callous stricture in a man sixty-three years old, in which there was a communication between the right bronchus and the oesophagus. Meyer (a) relates an instance of strictured oesophagus with a communication between the left bronchus and the oesophagus. Gendrin (b) communicates two cases of narrowing of the oesophagus at the region of the cricoid cartilage, in which there was also a fistu- lous orifice into the trachea, and cough in swallowing, vomiting fluids, speaking through the nose in consequence of the changed direction given to the air. 1599. In narrowing of the oesophagus from fungous growths fluids usually pass with more difficulty than solids; if the food be again thrown up, it is usually mixed with bloody mucus, and membranous fibres, which (a) Med. Vereinszeitung for Preussen, Chirurgicaks, Nov. 1837. See also SrnMm,-c 1838„No. 27. Jahrbiicher, vol. xxii. 1839 ; Oe.tr mSw (b) Journal des Connaissances Medico- Jabxbucher, vol. xxvii. pt. 2. *' etucm- ESOPHAGUS. 29 even on examination with the sound, present a yielding obstacle and be- come attached to it. 1600. The compression of the oesophagus by swellings of any kind in its neighbourhood, can be ascertained by careful examination of the neck; the difficulty of swallowing corresponds with the growth of these tumours, an oesophagus sound will pass more readily in this disease than in stric- ture. If such swellings be seatetrin the chest, the diagnosis is also more doubtful. See also in Kunze (a) the different observations on these swellings. Here also belongs the so-called Dysphagia lusoria depending on the unnatural course of the subclavian artery by which the oesophagus is compressed. Bayford (o) first described it under this name, and his observations have been confirmed by others. (Richter (c), Valentin (d), Autenrjeth) (e). By some this cause of Dysphagia is denied, (Fleischmann (/), Ruoolphi,) because the unnatural course of the subclavian artery has been noticed without this disease; and this notion is set- tled by Schonlein, as the origin of the dysphagy in this unnatural course of the subclavian artery depends on whether the artery pass before the trachea, between it and the oesophagus, or between it and the spinal column, in which latter case the disease must take place. The inconvenience first appears at the period of puberty, or on the suppression of menstruation, when the congestion towards the chest is greater. The symptoms are, violent palpitation and danger of suffocation on every attempt to swallow, accompanied with tremulous intermitting, and specially weak pulse in the right hand : the right arm is also shrunk and weaker; twisting move- ments of the neck frequently cause pain; all the inconvenience is in swallowing alone, and even then often only periodical. 1601. The spasmodic stricture of the oesophagus is usually seated more at the lower part towards the stomach, and is accompanied with the sen- sation of the tying together a fast-fixed substance ; sometimes the organs of swallowing and the muscles of the neck are in spasmodic tension; the evil is increased by cold drinks, and diminished by hot ones. It is ac- companied with spasmodic symptoms in other organs, qualmishness, vomitings, cough, secretion of a watery mucus, not unfrequently symp- toms of suffocation, loss of speech, and the like. The spasm frequently intermits ; this affection may, however, continue for a long while, which renders the diagnosis difficult; and also that, probably, during this long continuance, membranous stricture {par. 1594) will be produced. If spasm be added to organic stricture, the symptoms will be quickly in- creased. There is a difficulty in swallowing, which may amount to the greatest degree of dysphagy, dependent on a chronic inflammatory and consequent spasmodic affection of the upper part of the pharynx, and which, on account of its usual connexion with impetiginous diseases, and the peculiar change of the mucous membrane of the pharynx, I have distinguished as Angina impetiginosa. This disease develops itself without any decided cause, and after a catarrhal affection of the throat. The difficulty in swallowing increases gradually to a very great degree, so that it is often quite impossible for the patient to swallow, and the smallest portion of food or drink is thrown up, with which there are also spasmodic contractions in the throat, and difficulty of breathing. It is a peculiarity in this complaint, that it is more difficult to get down fluids, than more consistent mucilaginous substances; there is often such dread of fluids, that when brought to the mouth there is the most violent spasm of the glottis, so that every attempt to swallow is impossible. If the throat be [a) Above cited. (d) Journal de Medecine, Chirurgie, et (b) Memoirs of the Medical Society of Pharmacie. London, vol. ii. p. 251. (e) Pfleiderer (Praes. Autenrieth) Dissert. (c) Chirurgishe Bibliothek, vol. x. p. 365. de Dysphasia, lusoria. Tubing., 1806. (/) Neue Schriften der Erlanger phys. med. Gesellsch,, vol. ii. 30 TREATMENT OF examined by proper compression of the tongue, the hind wall of the pharynx is found • to be especially chano-ed; the mucous membrane has a net-like or latticed appear- ance, and between the paler streaks are perceived a few light red island-shaped elevations. The redness is very indistinct, rather pale, and inclining to yellow; at. several parts there is a sort of papular and phlyctenous formation. The patient com- plains usually, besides the difficulty in swallowing, of a burning or slabbing pain at some one part of the throat; he has often the sensation as if several little knots or bladders had formed and, burst, after which # wound, very sensitive to the touch, remains for some time. These sensations, as well as their places, alternate irregu- larly. The patient has frequently the sensation of a circular contraction at the upper part of the oesophagus. I have noticed this disease in young and old persons, and always perceived a certain disposition to previous, though inconsiderable chronic affection of the skin. The resemblance of the symptoms may mislead to the pre- sumption of an organic stricture, and many patients in this condition have been sent to me by distinguished practitioners; but an examination, with the oesophageal sound is, on account of the excessive sensibility of the throat, impossible, and the alternation Of the symptoms, and especially the peculiar appearance of the back of the pharynx, can alone determine the diagnosis. The treatment is one of the most difficult questions. In a young man the disease had withstood, for many years, the most different and severe remedies, both internal and external, employed by several practitioners; at last he submitted to mine; but, up to the present time, the observa- tions I have made point out no definite rule. Close consideration of all the previous circumstances, and constitutional relations, must lead the practitioner in the treat- ment, which requires equal perseverance on the part of both him and the patient. In one instance, repeatedly touching the back of the pharynx with lunar caustic seemed effective. To a certain extent this condition may be compared with the spasmodic contractions of the sphincter, in fissura ani. 1602. The prognosis, in stricture of the oesophagus, depends on the kind and seat of that affection. The simple, membranous stricture admits a favourable prognosis, and may be completely got rid of by proper treatment. Callous and scirrhous stricture rarely allows any check to its development, and, when once existing, its alleviation is scarcely possible, and still less its cure. Spasmodic stricture may mostly be got rid of by proper treatment; the disease however often recurs, is frequently very stubborn, and may run into organic stricture. In swell- ings which compress the oesophagus, the prognosis depends on their nature and seat. [Astley Cooper (a) mentions a case in which, during stricture of the oesophagus, an aperture was made from it outwards by ulceration; the patient was kept alive some time by administering food through an elastic catheter.__j. f. s.] 1603. In those cases in which the alteration of the mucous membrane of the oesophagus depends on chronic inflammation, a strict attention to the mode of living accompanied at first with antiphlogistic treatment repeated leeching, the continued internal use of hydrochlorate of am- monia, of hemlock, of mercury, of iodide of potash, with simultaneous derivation by issues, tartar emetic ointment, setons, and the like together with carefully-regulated living are required. The progress of 'the stric- ture is, however, rarely checked by these means; and its existence may be ascertained, m addition to the symptoms described, by the introduc- tion of a sound, in the way presently to be described, which finds a dis- tinct obstruction, and is stopped at the seat of stricture. 1604. The introduction of an oesophageal sound is the most simple remedy to get rid of an existent narrowing, by gradual extension. This (a) MS. Lectures. GESOPHAGUS. 31 treatment in membranous stricture ensures a satisfactory result; in callous and scirrhous stricture it is never, according to my experience, to be relied on. The introduction of the sound has frequently only the pallia- tive effect of prolonging the patient's life, by the passage of food into the stomach. In such cases, however, the irritation of the sound may, with- out delay, drive on the stricture into malignant degeneration and ulcera- tion. 1605. The introduction of a sound into the oesophagus must be con- ducted with the greatest care and delicacy, or otherwise injury to the walls of the oesophagus, false passages, and hastening the miserable end of the disease will be produced. The following is the best mode of pro- ceeding. The patient sits upon a chair, his head moderately thrown back, and held by an assistant, his mouth wide open, and tongue a little protruded (1). The oesophageal sound provided with a leaden stilette, oiled, and a little curved at its tip, is then introduced into the gullet, and gently pushed onwards. When it has reached the seat of stricture, care must be taken, and an attempt made, by gentle pressure, to overcome the obstacle, over which it usually slips with a jerk, and can then be passed still farther. If it be impossible to get through the stricture with the sound, a thinner one must be chosen and used in the same way. In some cases of great narrowing, I could only succeed, after several fruit- less attempts with the thinnest oesophageal sound, in passing through the stricture with a moderate-sized urethral sound. The instru- ment thus introduced, and the stilette withdrawn, must be allowed to remain as long as the patient can, without much inconvenience, bear it, which at first will not exceed five minutes. In genera], the swal- lowing after this first introduction of the sound, very small though it be, will be remarkably improved. The sound should be passed daily in this manner, and allowed to remain a little longer, so that the parts may become accustomed to the irritation, and then by degrees a thicker sound may be used. The introduction of the sound through the nostril is improper, much more painful to the patient, and, if it be thick, impossible; by this mode also the instrument more frequently slips into the windpipe, than in passing it by the mouth. This is proved by the violent disposition to cough, by the expulsion of the air with the sound, and the impossibility of speaking; it is ri lano's and Himly's Journal, vol. vi. pt. i. 1811. von Wv, Beobachtungen iiber Verwachsung des Mastdarmes. Ibid. Copeland, Thomas, Observations on the principal Diseases of the Rectum and Anus, particularly Stricture of the Rectum, &c. London, 1814; Second Edition. White, M., Observations on Strictures of the Rectum and other affections. Bath, 1820; Third Edition. Howship, J. A., Practical Observations on the symptoms, discrimination, and treatment of some of the most common Diseases of the Lower Intestines and Anus, &c. London, 1820. 8vo. Wandesleben, F., Dissertatio de Intestini Recti Strictura. Hal., 1820. (a) Genorin, Du Catheterisme curatif du Retrecissement de l'QSsophage; in Journal des Connaissances Medico Chirurgicales. Nov., 1827. Vol. hi.—4 34 CONGENITAL CLOSURE Calvert, George, Practical Treatise on Haemorrhoids or Piles, Strictures, and other important Diseases of the Urethra and Rectum. London, 1824. Salmon, Fred., A Practical Essay on Stricture of the' Rectum ; illustrated by cases showing the connexion of that disease with affections of the Urinary Organs and Uterus with Piles, and various constitutional complaints. London, 1829; Third Edition. Hehenus, A. V., Ueber die verschiedenen Formen der Verengerungen des After- darmes und deren Behandlung. Leipzig, 1828* Flachs, Dissert, de Atresia Ani congenita. Lipsiae, 1834. Tanchou, S., Traite des Retrecissements du Canal de l'Uretre et de 1'Intestine Rectum, contenant I'appreciation des divers moyens employes dans le Traitement de ces Maladies. Paris, 1835. 8vo. Brodie, Sir B. C, Clinical Lecture on Stricture of the Rectum, &c.; in London Medical Review, vol. xvi. 1835. Bushe, George, M. D., A Treatise on the Malformations, Injuries, and Diseases of the Rectum and Anus. New York, 1837. 8vo. Syme, James, On Diseases of the Rectum. Edinburgh, 1837. 8vo. von Ammon, Chirurgische Pathologie in Abbildungen, part i. pi. x. 1609. Closure of the Rectum (Imperforate, Atresia Ani, Lat.; Ver- schliessung des Mastdarmes, Germ.; Imperforation du Rectum, Fr.) is always a vice of the first formation ; but Stricture (Strictura Ani, Lat.) . Verengerung des Mastdarmes, Germ.; Retrecissement du Rectum, Fr.) most usually arises subsequently, and is rarely congenital. 1610. The congenital closure of the rectum depends either on a simple membrane, which more or less resembles the general coverings or the intestinal membrane of the gut, and is situated either immediately at the ,anal aperture, or more or less high in its cavity; or there is not a trace of anus, and the rectum opens more or less high in a blind sac. Those cases of congenital malformation must be now also mentioned, in which the rectum opens into the urinary bladder, urethra, or some other aper- ture, whilst the anus is closed. Compare von Ammon (a) upon the unnatural openings of the anus, and the other malformations therewith connected. 1611. Closure of the rectum always causes violent forcing and strain- ing; with which, nothing being discharged by the anus, painful tension of the belly, vomiting of green or yellowish matter, arise ; and to these symptoms convulsions are afterwards added. If the rectum be closed by a simple membrane, it is, especially when the child ciies, protruded like a sac, and the meconium is seen through it. If the closing mem- brane be higher, it is ascertained by the introduction of the finger or of an elastic sound. [Although imperforation of the anus or rectum is generally soon discovered by the child not passing motions, yet a case is mentioned by Wolff (b), in which it was not found out till the evening of the twelfth day after birth, when the child was attacked with vomiting, hiccough, and convulsions; the belly was very full and tender. The anus was found imperforate, but the gut could not be opened bv a lancet thrust into the depth of two inches. A pharyngotome was then passed up and with it an aperture made, and by the use of clysters and tents the child ulti- mately recovered.] 1612. If the external opening of the rectum be closed by skin it is -sufficient to thrust into it a straight bistoury, and to enlarge the wound ■with a button-ended bistoury on a director; and, if it seem necessary tjae flaps thus formed may be removed with the scissors, If the closed £a)Cited at t!ie head of article. (6) LANGENBECK,sBibliothekrvcl.jii,p,23] OF THE RECTUM. 35 part of the rectum be higher up, a narrow, straight bistoury must be introduced, in a proper direction, upon the forefinger of the left hand, or upon a director, through the closing membrane, and the opening thus made enlarged with the button-ended bistoury; a trochar or a pharyngo- tome will answer the same purpose. This treatment is, according to the kind of closure, accompanied with more or less difficulty; the expanded part of the rectum, instead of the seat of closure, may be lighted on, and fatal effusion into the pelvis follow. The closed part may be hard, cal- lous, cartilaginous, and very thick. To prevent the reclosure of the rectum, it is necessary to insert a plug of lint, fastened up with strips of sticking plaster, and with a thread attached to it, for a long while in the cavity of the gut, or to introduce the finger, well oiled, from time to time into the rectum, as the disposition to reclose is often very considerable (a). 1613. When there is no trace of an external anal opening, the diffi- culty of the operation depends on the higher or lower position of the blind end of the rectum. If there be no fluctuating swelling, no accom- panying projection or depression, which can direct the practitioner, he then, after carefully introducing a catheter into the bladder, and in a female a sound into the vagina, for the purpose of emptying the urine, and distinguishing, during the operation, the position of the bladder and vagina, makes a cut with a pointed bistoury between the beginning of the raphe and the coccyx, in such way, however, that there be an inch distance between the latter and the cut, as in children the rectum does not lie so close to the coccyx as in adults. Having penetrated about half an ineh, the finger of the left hand must be inlroduced into the wound, the blind end of the gut sought for, and then the cut is to be cautiously continued more deeply, following, as far as possible, the course of the straight gut, and taking care not to wound the bladder or vagina. When the cavity of the rectum is penetrated, the aperture made must be enlarged with the button-ended bistoury, on the finger or on the director, and the dressing to prevent the reclosure applied in the usual way. If the penetration have reached a depth of two inches, without coming to the gut, it has been advised to proceed with the operation by thrusting a trochar towards the blind end of the rectum; the objection, however, seems to be correct, that the operation is equally hazardous and useless, as, although the gut may be opened, effusion of meconium into the belly is the consequence (6). Here also may be mentioned Amussat's (1) mode of practice, in which he draws forth the blind sac of the intestine exposed by the cut, opens it, and attaches the cut edges of the gut to the edges of the external skin. (1) Amussat (c) found, on introducing his finger into the vagina, a movable body on the top of the sacro-vertebral articulation, which he took for the end of the rectum. He made one transverse cut behind the proper seat of the anus, and then another which reached the coccyx. Through this T cut he introduced his finger, carrying it along the sacrum to the end of the gut, and therewith broke down the adhesions; he then drew the intestine with a pair of forceps, to the external opening, cut into it, and fixed it with two stitehes, so that the mucous membrane overlapped the edge of the external skin. [Sometimes the two portions of the ileo-colic valve are adherent to each other, so (a) Henkel, Neue Bemerk., fasc. i. p. 11. (c) Archives generates de Medecine, 1835. (b) Zang, Darstell. blut. heilk. Operat, vol. p. 237. iii. pt. ii. p. 436. 36 CONGENITAL CLOSURE as to prevent the passage of the meconium, and lead to the presumption of the large intestine being imperforate in some part of its course. A case of this kind occurred to me at the General Lying-in Hospital, in the summer of 1842. The child was born at 1 a. m., June 6; and some hours after, no motion having passed, castor oil was given, but did not operate. On the evening of the same day, an elastic catheter was introduced into the rectum, to the extent of two or three inches, and no obstruc- tion being met with, the castor oil was repeated, but did not produce any stools. On the following morning an attempt was twice made to throw up an injection, but it failed; and Dr. Ferguson, whose case it was, considering it as one of imperforate rectum, desired I should see the child ; and on the evening of this day I saw her. On examination, I could pass my finger up about two inches, but not farther, and the gut seemed to terminate in a blind pouch ; no sensation of fluctuation above could be felt; and I therefore did not consider myself justified in passing a trocar, . without knowing where it might go; but, being desirous to give the child a chance of life, I determined on making an artificial anus. For this purpose I cut upon the linea alba about half an inch above the pubes, and, opening the peritonaeum, caught up a portion of small intestine, and having cut into it, fixed the cut edges by stitches to the wound in the linea alba. Soon a quantity of meconium passed, and continued to do so on the day following; but on the third day she began to vomit bile and frothy mucus, and at 2 p.m. died. On examination, the gut was found adherent to the wound. The colon was quite empty and contracted to the size of a crow-quill, but it was continuous with the rectum, and both intestines were quite pervious. The finger had been prevented passing up the rectum by a sudden turn, at which part it was close bound down to the sacrum. The jejunum and ileum were much distended with faecal matter; and on slitting open the latter, the two portions of the ileo-colic valve were so nearly adherent, that nothing would pass through, although there was a very small aperture.—j. f. s.] 1614. When the rectum opens into the vagina, a director must, if possible, be introduced through the latter into the anus, thrust down vertically, and, when its position has been ascertained by the forefinger, a straight bistoury or a trochar must be thrust through" the closed anal aperture, towards the groove of the director, and the puncture after- wards enlarged in the manner described. This practice is, however, generally fruitless, and it is preferable to divide, through the vagina, all the parts back into the rectum, and by the insertion of lint, or, still better, by the daily introduction of the finger, oiled, to pre-ent the re- union. In one case, in which this treatment was in vain, as the artificial opening of the rectum closed again, whilst the opening of the vagina remained, Barton (a) em- ployed the following method with success. He passed a director through the hole of communication in the vagina, and divided the whole wall of the vagina to the place where the natural opening of the rectum should be. He did not use any dressing, but every day passed the finger, smeared with cerate, into the rectum to prevent its closing. The vagina was perfect, and the rectum had a direct opening, except that the stools passed involuntarily. Satchell (6) also, and I myself have by this practice obtained like favourable results. Velpeau (c) had proposed this operation on the recommendation of \ icq. d'Azyr. After the division is perfected, a canula should be introduced into the rectum, fixed towards the hind angle of the Tabled L^^Lw"^ ^ ^^ * "* *™™«> «* *e *&ed parts Dieffenbach (d) introduced a director much h^nt inwove *u, u a into the aperture of ,he „*», thrust a vcA'XST^A^TSZ of the ani,, at a siogle sttoke, te JafcZJm™ ™d Remits the aperture division of the eelh.ll, tissue, stre^in/L'S* S"^ ST^SSSrV, the OF THE RECTUM. 37 bottom of the wound. He then dissected the edge of the rectum from the wound he had made, divided to the extent of an inch in the direction of the external skin and the muscular wound, and fastened the separated edges of the rectum on each side of the cleft perinaeum. The aperture of the rectum in the vagina closed very com- pletely during the after-treatment by occasionally touching it with lunar caustic. On the complete cure of all the wounded parts, three weeks after the first operation, the formation of a new perinaeum was attempted. The hind surface of the'open end of the rectum was farther separated from the vagina. The portion of intestine thus set free in the middle, contracted remarkably, and receded about four or five lines. The scar of muscle and skin was removed from the thus formed interstice, the deeper- lying parts were brought together with a needle-stitch, but the edges of the wound with two very short harelip-pins and the twisted suture. The cure was completely successful. 1615. When the rectum opens into the urethra, a sound must be passed by the latter into the bladder, and the unnatural opening in the urethra divided upon it towards the coccyx, and with some cautious strokes of the knife the aperture in the urethra and the wall of the in- testine opposite the place of the anus divided. If possible, the sound should be brought through the unnatural opening in the urethra, into the cavity of the rectum, and such direction given it, that it may be distinctly felt from the perinceum, and the covering of the urethra divided in the course of the raphe, together with the wall of the straight gut opposite the place of the anus, or treated according to Amussat's plan {par. 1613.) When the rectum opens into the urinary bladder, it is possible for a girl to live, on account of the shortness and extensibility of the urethra; but in a boy this malformation is fatal, if the wall of the rectum, op- posite the place of the anus be not'open, or an artificial anus made. In a case, in which the rectum was imperforate, and opened into the bladder Fergusson (a) made a cut into the neck and body of the bladder at the place of the anus. [Cruvelhier (6) gives an instance in which the rectum opened under the glans penis, by means of a canal which was formed in the substance of the raphe scroti. A similar case to this occurred to me, and will be described at the end of par. 1617.—j. f. s.] 1616. In all cases, where, by the above-mentioned modes of treat- ment, opening the imperforate end of the rectum is impossible, or when the rectum terminates by a blind end in the belly, as also in the not-to be-overlooked narrowing of the rectum by unreachable strictures and the like, some assistance, though not much, may be afforded by the formation of an artificial anus at the lower end of the colon, (laparo- colotomia,) which may be performed in two ways. First, A cut from an inch and a half to two inches long is to be made obliquely from behind forwards, so that its lower end should be a little below the upper front iliac spine, and half an inch from it, and continued, layer after layer, through the skin and muscles; the peritoneum is then care- fully opened, raising it with ihe forceps, and the sigmoid flexure of the colon sought for, drawn to the wound, two waxed threads carried round it, and a longitudinal cut having been made in it, returned into the belly; and, by means of the threads, retained between the edges of the ex- (a) Edinb. Med. and Surg. Journ., vol. (b) Anat. palhol., livr.i. pi. v. 1. fig. 6. xxxvi.p. 363. 1831. 4# 38 OPERATION FOR CONGENITAL ternal wound with which it unites (1). Second, In order not to wound the peritonaeum, a cut, three inches in length, must be made, according to Callisen's (2) method, in the left lumbar region, between the iliac crest and the short ribs, on the front edge of them, quadratus lumborum, at which part of the descending colon lies enclosed in cellular tissue externa] to the peritonaeum, and is here fo be opened {a). Amussat makes a transverse cut two inches above the iliac crest, from the outer edge of the m. quadratus lumborum to the middle of the iliac crest, through the skin and abdominal muscles, thus cutting across the m. transversalis and its aponeurotic layer, then separates the fatty tissue which covers the gut, passes two threads through its wall, to prevent it falling together; then stabs the colon with a trocar,'enlarges the aperture with the bistoury in several directions, and connects it by four stitches to the front corner of the wound (3). (1) This operation was proposed by Littre in 1720; but first practised success- fully by Dinet in 1793 (b). See also Freer (c). (2) This mode was tried by Roux without success. (3) Amussat has performed this operation successfully in a woman of forty-eight, and in a man of sixty-two years of age (d). , Pilore (e) made an artificial anus on the right side, by which he opened the caecum as previously advised by Benjamin Bell, and as was to be done in the immobility of the S. Romanum. The formation of an artificial anus has been also proposed in adults, for the not- to-be-overlooked narrowing of the rectum from unreachable strictures, and the like. Freer (/) made a longitudinal cut, of three inches in the left iliac region, about an inch above the upper front iliac spine, and an inch and a half in front of it, laid bare the colon fastened it with two stitches in the wound, and opened it longitudinally to the extent of two inches. The patient died on the tenth day. Pring (g) made a cut obliquely downwards, and inwards two inches above, and an inch on the inner side of, the front iliac spine, to within three-quarters of an inch of Poupart's ligament, through the skin and muscles; opened the peritonaeum, and enlarged it to three inches. The sigmoid flexure of the colon was laid bare to the wound. The result was successful. [See A6hmead, On a new operation for Artificial Anus, in Transac- tions of the College of Physicians of Philadelphia, vol. i. p. 97. 1842. G. W. N.] Compare also Martland, a case in which the operation for artificial anus was successfully performed; in Edinb. Med. and SuTg. Jour., vol. xxiv. p. 271. 1825. Svitzer, E., Anotationes in Colotomia. f'afnae, 1827. Oettinger, Ueber die angeborene Aftersperre. Miinchen, 1826. Loper, Dissert, de Vitiis fabric® primitivae Intestini Recti. Wirceb., 18-27. Klewitz; in Med. Zeit. des Verein. fur Heilk; in Preuss., No. 17, 1835,—No. 22, 1838. Although in imperforate anus, if no assistance be rendered, fatal consequences ensue, in consequence of the stools not being passed ; there are, however, instances in which, with imperforate anus, and even with accompanying deficient urethral opening, life has been sustained months (A), and even years (*); in which cases the stools have been vomitted by the mouth. 1617. When the anus, though not imperforate, is yet congenially ^Sys,lema ChirurgiBB Medicinae, vtl. ii. (e) Actes de la Soci^te de Lyon" 1797 n p. 842. Hafn., 1817. 189. ' P (6) Sabatier, Med. Oper., vol. ii. p. 336. (/) Above cited, p. 31. (c) Pring : in London Medical and f hysi- (?) Above cited p 4 cal/ Journal, vol. xlv p. 9. 1>21. (Jl) Delamarre'; in Journ. de Medecine (d) Memoirs sur la possibility d'^tablir un vol. xxxiii. p. 510. 1770. ' Anus Artificiel dans la region Iomb.,i e sans (i) Baux ; in same vol viii n or every other daV< W ™J at last get £?, t*\ feculent accumulation d.ssolved, and empty "the reservoir. When reneated tZ T™™* 'f^' the lnjfCtion °f Warm water should be constantly repeated, so as to prevent the accumulation taking place again." (pp. 29, 30.)] 1634. Stretching, by which the narrowed part may be enlarged and the consolidation of the cellular tissue accompanying it overcome is effected, with plugs, wax, and elastic bougies, spoJgeW with metal- lic, linen, or goldbeater's skin dilators, and the like. 163o. The plugs of lint which Desault used with the especial object STRICTURE OF THE RECTUM. 49 of introducing medicated substances,, are carefully passed into the stric- ture with a plug-holder, after having been smeared with mild ointment, to which extract of belladonna, or cicuta have been added; or an injec- tion of decoction of cicuta is made. The plugs should be made thicker, and allowed to remain up for a longer time, according as the patient can bear them. As their introduction with the holder is often difficult, and the plug completely closes the rectum, so as even to prevent the escape of air, Tanchou has proposed fixing the plug on an elastic metal canula, and to introduce it on a silver button-ended probe, first passed into the stricture. 1636. Elastic and wax bougies, of corresponding size, are introduced into the stricture. Properly prepared wax bougies, of from one to three and half inches in circumference (Salmon) are the best. In introducing these bougies the following rules are to be observed, according to the different heights at which the stricture is situated. The bougie, curved according to the curvature of the rectum, and well oiled, with the con- vexity corresponding with the first curve of the gut, and directed towards the sacrum, is thrust in upwards and backwards, in this direction, to the extent of two inches. After a little waiting, the bougie is introduced still higher, from three to three and a half inches above the second curve of the rectum; the inner extremity of the bougie still remains in the hol- low of the sacrum, and the outer end is inclined to the left side. If the bougie be introduced still further, its direction must be changed, the outer end being raised from left to right in a semi-circle, and pushed forwards at the same time, and in this manner it may be introduced yet four inches further. If the instrument have to be passed into the sigmoid flexure its outer end must be pressed gently down, and pushed upwards, till it be completely carried in. The deeper the instrument is introduced the more care must be taken, lest dangerous irritation, or even perfora- tion, of the sigmoid flexure should occur. There is, commonly, pain over the whole belly, and violent forcing. The contraction of the sphincter causes the most difficulty; the bougie, therefore, of different • length, according to the seat of stricture, is to be well passed into the rectum, and there retained by means of a bandage attached to it. The patient should keep quiet in bed, and the bougie allowed to remain in, not longer than from six to ten minutes, nor so long, if the patient corn- plain of severe pain. Its introduction is to be repeated every two or three days, its size increased, as also the time it should remain, accord- ing to the patient's irritability, but every violent irritation should be carefully avoided. I have used elastic bougies, with a dilator, as in nar- rowings of the oesophagus, (par. 1606,) which I once introduced into a stricture, and repeated every two days, as dilatation, continued, for some time, easily sets up considerable irritation, and even becomes unmanage- able. In strictures, situated high up in the rectum, the elastic or wax bougies are the only remedies which can be employed. [Brodie observes :—" In a great number of cases, where the the disease is far advanced, you cannot resort to the use of the bougie in the first instance, or, if you do, it must be employed in combination with other remedies. It will be necessary to lessen the irritability of the bowel by the introduction of aa opiate suppository every night, and a gentle aperient taken in the morning. The patient may take a combination of caustic potash with, copaiba; half a drachm of balsam of copaiba,. 50 TREATMENT OF fifteen minims of liq. potass, three drachms of mucilage of gum arable, and about nine drachms of carraway water. A draught of this composition may be taken three times a-day with very great advantage. Bryant, of Edgeware-road, recommended to me a decoction of Achillea millefolium, which I have employed in some of these cases with manifest advantage. About two ounces of the Achillea may be put into a pint and a half of water and boiled down to a pint, of which the patient may take a wine-glass full three times a-day." (p. 29.) With regard to the use of bougies in stricture of the rectum, Lawrence says:— " It is a question how far the stricture can be relieved by the introduction of bougies. "When the stricture is situated so near to the anus that you can examine it with your finger, and when you can, therefore, ascertain with considerable certainty something of the state of the bowel, when you can ascertain, by such means, how far the me- chanical irritation of dilatation will be borne, you may cautiously use bougies, as in the case of stricture of the urethra, but you must employ them under the same kind of restrictions and cautions as in that case. Indeed, you may find it necessary to be even more cautious in the case of the rectum than in that of the urethra, inasmuch as you are so much uncertaiu, when you meet with a difficulty, whether you are pressing against strictured or sound parts of the gut. You must employ instru- ments which will not be likely to injure the bowel. Very commonly you find instruments of elastic gum recommended for this purpose, which have the advantage of being sufficiently smooth, but they do not readily accommodate themselves to the course of the canal: I do not consider them eligible instruments. Therefore you had better use rectum bougies, made of a soft composition; and, I consider, indeed, that the common plaster bougies, used for the urethra, are not of a sufficiently soft substance for a rectum bougie. There are rectum bougies, made for the purpose, of a composition so soft, that if you dip them into tepid water, they will be immedi- ately softened, and very well adapted for the purpose. These are what I would recommend; and you should never employ any force." (p. 856.) "In some cases of stricture of th& rectum," Brodie says, "I have thought that the patient has derived benefit from the application of mercurial ointment to the inside of the gut, which is easily managed in the following manner. Let the bougie be covered with lint smeared with mercurial ointment; the bougie, thus anointed, must be allowed to remain in the stricture for a few minutes dailv." fo. 30.)] J ^ 1637. For the purpose of increasing the extension at pleasure, and to operate specially upon the narrowed part, peculiar dilators have been proposed by Arnott, Bermond, and Costallat. Arnott, Ss well as Charles Bell, introduces a piece of prepared gut, by means of a sound, into the stricture; the distension of the former is effected by blowing in air, and of the latter by injecting water. Bermond's {a) and Costal- lat's (b) apparatus consists of a little bag of linen or gold-beater's skin, introduced into.the stricture, and by filling it with lint, extension can be made specially at the seat of the stricture. The constant distension pur- posed by these apparatus easily excites violent irritation and pain which is unbearable. 1638. In the dilatation by metallic means, as the dilators recom- mended by Weiss and Charriere, for which also Astley Cooper em- ployed a pair of narrow forceps, the distention is effected gradually and repeated m a few days. Astler Cooper (c) in this way established the calibre of the bowel in course of a few weeks, in two instances. Dilata- tion with metallic instruments can only be employed in valvular and recent strictures which are not complicated with hardening or inflam- mation. & (a) These, 1827—Velpeau, Elemens de tion r^rtfcuueremenfcappliq^auxretrpcisse Kuepf.pr330V.°L 1I'P-988-F—'• ^ir. mens.du Rectum. PaTis? [sT.Zt^Z (b) Essai sur un nouveau mode de Dilata- (c) Tanchou,. above cited. STRICTURE OF THE RECTUM. 51 1639. Cutting into the narrowed part, generally objected to by many surgeons, can be employed only in valvular or circular strictures which can be reached with the finger, and are unconnected with inflammation, hardening, or hypertrophy. In hardening, and in carcinomatous degene- ration it always produces bad symptoms. A button-ended bistoury is to be carried in upon the introduced finger of the left hand, or upon a director, and the bridges divided with it, or several notches made in the stricture, at proper distances apart from each other or at the most pro- jecting part. If possible these cuts should be made towards the sacrum, and always with care not to extend beyond the bounds of the disease, nor to cut open the walls of the bowel itself. Wiseman (a) first made use of such cuts in stricture of the rectum. Copelano (6) says :—"In the indurated annular stricture, which has for a long time resisted the introduction or the enlargement of the bougie, I have more than once introduced a probe-pointed curved bistoury, and divided the thickened parts, on that side of the rectum which is contiguous to the sacrum; and I have frequently seen the late Mr. Foitn perform the same operation. Wiseman divided a contracted gut three or four times in the same person; his case, however, was not one of idio- pathic stricture, but was produced by the rude operation for fistula in ano, which was practised at that time." (p. 32.) [Brooie recommends the division of the stricture, in the following manner:— " Introduce a bistouri cache, and let the screw be so adjusted that the blade may be opened about the sixth of an inch, but certainly not more than a quarter of an inch. The bistouri must be introduced with the blade shut; then press on the handle, open the blade, and drawing it out, you nick the stricture first in one part of its diameter, then in another, and then in a third.. This being done, a larger bougie may be intro- duced than could be done before, and the cure is very much expedited." (p. 29.)] 1640. Extirpation can only be employed in narrowings of the rectum dependent on tuberculous excrescences, when situated at the edge or in the lower part of the rectum, from whence they may be drawn forth, or protruded by straining at the anal aperture,and being held with forceps or by a thread passed through them, may be removed from their base with knife or scissors without danger. Schreger, from experience, prefers extirpation in such cases, although it had been objected to by Desault. If the excrescences be seated higher, extirpation can only be performed under certain conditions as to their form, that is, when they are provided with a neck. No important symptoms follow this opera- tion, as the absence of vessels in these excrescences and their insensi- bility prevent bleeding, and sympathetic affection of the rectum, and the internal coat readily shoots over. If the excrescences be situated higher than we can venture without danger to extirpate them, the removal of those nearest the anal orifice will, however, relieve the patient's condi- tion; the application of pressure sufficient to efface those above facilitates, and considerably shortens the cure. Compare Rognetta (c) in reference to those warts of the rectum, which in their tissue precisely resemble warts on the skin, and must be removed though they fre- quently return. 1641. Cauterization with a bougie armed with lunar caustic has been employed by Home {d) in ring-shaped stricture of the rectum, and cau- (a) Several Chirurgical Treatises, p. 239. (d) Practical Observations on the Treat- London, 1676. fol. ment of Strictures of the Urethra, &c, vol. (b) Above cited. ii. p. 418. (c) Gazette Medicale, vol. iv. p. 387. 1836. 52 TREATMENT OF STRICTURE OF THE RECTUM. terization with dilatation by Sanson, in three cases, though without particular effect. (Tanchou.) Sanson has recommended a caustic- holder similar to that of Ducamp; Tanchou employs an elastic catheter, opened at the side, into which he introduces a second fitted with caustic. Cauterization must always be considered a very uncertain mode of treat- ment : it can only be of use when properly performed, and the dilatation is sustained (a). 1642. If, in the course of this disease, fistulse form about the rectum, the treatment must first be directed towards the stricture, and when that is got rid of, the fistula may be treated in the usual manner. If the disease be cancerous, alleviation only can, in most cases, be obtained by thin plugs, smeared with softening and soothing ointments, by injections of decoction of cicuta, suppositories of hyoscyamus, bella- donna, and the like. But, if the disease be seated at the lower part of the rectum, if its upper boundary can be reached with the finger, if the cellular tissue surrounding the lower part of the gut be healthy, the bowel moveable and permitting its drawing down, the extirpation of the cancerous part, according to Lisfranc's (6) proposal, may be under- taken. 1643. The patient being placed as in the operation for the stone, two semi-circular cuts should be made about an inch in front of the anus, which, dividing the parts to the cellular tissue, should meet behind. The intestine is then to be dissected from its connexions till it is completely set free all round. The forefinger, half bent, is now to be introduced into the gut, and sufficiently drawn down to make the mucous membrane protrude, so that a portion of it can be easily removed with eurved scis- sors, or with the knife. If the cancer affect the whole thickness of the intestinal wall, and do not extend more than an inch upwards, the whole gut must be everted, and the entire disease laid bare. The everted part is then to be cut into, parallel to the axis of the trunk, and cut off with the curved scissors. Should the cancer have affected all the membranes of the intestine and the neighbouring cellular tissue, then after the first two cuts have been made, and the lower part dissected, a cut must be made with a pair of straight scissors upon the introduced forefinger, through the whole wall of the intestine backwards, where few vessels and the peritoneum can be wounded, and which has also the preference of rolling out the gut and laying bare the disease at the same time, after which it is to be removed with scissors in the sound part. In operating on men, a catheter must be kept in the bladder, to prevent injury to it. The bleeding vessels must, as far as possible, be tied, or sponge dipped in cold water, or a sufficiently thick bundle of lint introduced. If the bowel have been plugged, the plug must, after some hours, be renewed. For the purpose of preventing the narrowing of the gut whilst the scar is forming, a pretty large bundle of lint must be introduced, and there kept, during suppuration, for a month. This operation is more difficult in the female than in the male, and an assistant must keep his finger in the vagina to prevent its injury, whilst the operaSTro- ceeds In the female, after an oval eut is made, distant about three qua™ Jan inch from the opening of the rectum, and continued to the gut, the rectum must be (a) Tanchou, above cited, p. 182. (fe) R6vue Medicale, vol. iii. 1830,. p. PHIMOSIS. 53 gently pulled, and two inches of its side and-hind part removed, without injuring the vagina. The projection which the rectum forms in front is about sixteen lines, on account of the connexions it has with the vagina, which, formed of an aponeurotic tissue, and very thick cellular tissue, stretches through the muscular fibres from the fatty tissue beneath the skin, at a depth of three lines. When, in the female, the rectum is dissected up to the attachment of the peritonaeum, and drawn by means of a pair of forceps, there is a space of six inches forwards, and aside between the lower end of the bowel and the peritonaeum, but behind we may proceed still higher, on account of the meso-reclum. In the male, the distance from the anus to the peritonaeum is about four inches. 1644. When the narrowing depends on a large scar, nothing more can be done than to cut deeply into it at several places, and to widen the anal aperture by the introduction of plugs, lint, or sponge. ^ In the narrowing of the rectum by tumours in its neighbourhood, which impress it, the prognosis and treatment are guided by their situation and con- dition. A "narrowing of the anus by growing together of the buttocks, as the conse- quence of badly treated ulceration, so that the motions are only as thick as a feather stem, and for the most part involuntary, Rust (a) cures completely by division of the united buttocks. 1645. If narrowing of the rectum run on to closure, and ileus be pro- duced, the formation of an artificial anus is required, although always a very doubtful remedy {par. 1616.) IX.—OF GROWING TOGETHER AND UNNATURAL CLOSURE OF THE PREPUCE. Petit, J. L., Traite des Maladies Chirurgicales et des Operations qui leur con- viennent, vol. ii. p. 421. Zier, Dissertatio de Phimosi et Paraphimosi. Jena, 1785. Muller, De Phimosi et Paraphimosi earumque curatione. Erf., 1797. Loder, Medicinisch-chirurgische Beobachtungen, part i. p. 84. Weimar, 1794. Travers, Benj., On Phimosis and Paraphimosis; in Cooper and Travers' Surgical Essays, part i. London, 1818. 8vo. Kirnberger, Theoo., Historisch-kritische und pathologisch-therapeutische Ab- handlung iiber die Phimosis und Paraphimosis. Mainz, 1834. 4to. Collin, Die Beschneidung der Israeeliten. Dresden, 1812. Terquem, Guide de Posthxtomiste, avec un expose d'un nouveau procede. Metz, 1843. Bergson, J., Die Beschneidung vom historichen, kritischen und medicinischen Stanpiinkte. Berlin, 1844. With a plate. 1646. The unnatural narrowing of the prepuce, so that it cannot be readily retracted over the glans penis, is called Phimosis; and if the very narrow prepuce which has been retracted cannot be again brought forward, it is named Paraphimosis. 1647. Phimosis is either a vice of the first formation, and congenital, or it may be accidental, from inflammation of the glans and prepuce; in which latter case it is named by some complicated phimosis, in opposition to the first form. 1648. The prepuce, in children, has generally so narrow an aperture, that it cannot be retracted over the glans ; and peculiar symptoms may occur if this aperture be very narrow or entirely closed. When, for (a) Magazin, vol. i. p. 237. 54 TREATMENT example, the orifice of the prepuce is smaller than that of the urethra, the urine cannot flow in its usual stream, part of it collects under the pre- puce, distends it, and can only be completely voided by pressure. By the urine thus retained, and becoming putrid, the prepuce is inflamed, often lengthens and becomes hard; and even stony concretions may be formed between the glans and the prepuce. If the prepuce have not an opening, it becomes distended by the collecting urine to an oval trans- parent swelling, and the retention of urine may be fatal, if assistance be not afforded in proper time. 1649. If the congenital narrowing of the prepuce be not so great as to produce the just mentioned symptoms, it is rarely noticed before puberty. If the erections of the penis then occurring be not sufficient, by degrees, to enlarge the aperture of the prepuce, so that it can be easily retracted over the glans, which depends on the great length of the prepuce or the shortness of the frtenum connecting the prepuce and glans, or it may be on the imperfect development of the penis itself, erection and connexion will be painful; inflammation, excoriation, and so on, will be produced by the obstructed flow of the urine, and by the collection and putrifying of the cheese-like matter beneath the prepuce; and also the proper ejec- tion of the semen will be prevented by a very small orifice of the pre- puce. 1650. Accidental phimosis arises from inflammation, in which, as con- sequence of swelling of the prepuce, its aperture contracts, and, as consequence of increased determination of blood, the glans itself en- larges. Usually, those persons are attacked with accidental phimosis who have, from birth, a very long and narrow prepuce. The special causes may be, venereal ulcers, when seated on the edge of the prepuce, upon the corona glandis, or on the frcenum, internal or external gonorrhoea, warty excrescences, and excoriation of the prepuce from putrescence of the cheese-like matter retained beneath it, or from any other irritant. The inflammation is either acute or of an erysipelatous kind; often is the prepuce swollen with oedema. Phimosis may also be produced by any chronic swelling and thickening of the prepuce, as in hardening, in scirrhous or any other degeneration. 1651. The symptoms caused by such phimosis vary according to its degree and its cause. In venereal ulcers upon the corona glandis, if the pus be retained, the prepuce may be gradually eaten through, and the whole glans often protrudes through the whole. The inflammation may run on to gangrene, which is particularly to be feared in adults, and if mercury have been previously and frequently used; the urine collected beneath the prepuce may cause excoriation, may be effused into the cel- lular tissue of the whole penis, and producing gangrene, cause its de- struction. The swelling may even be so great that the glans and urethra may be partially compressed. If the inflammatory stage pass by, a chronic phimosis may remain, in which there is a hard, cartilaginous swelling of the prepuce, or growing together of the prepuce and glans. bnould the obstruction to the voidance of the urine by the narrowness of the prepuce, affect the bladder and urethra, distension, weakness and even palsy of those parts may be produced. ' 1652. The treatment of phimosis consists in removing the narrowin OF PHIMOSIS. 55 by operation; or in phimosis, accompanied with inflammation, by reme- dies capable of diminishing the swelling of the prepuce and glans. In children this operation is only called for when there is complete closure of the prepuce, or the congenital phimosis is to such degree that it pre- vents the discharge of the urine, and in adults, when, besides the voidance of the urine, the discharge of the semen is also stopped, connexion pain- ful, or if the orifice of the prepuce have a cartilaginous ring. If the narrowing of the prepuce be only slight, softening rubbings-in, bathing, and repeated daily attempts to retract the prepuce, are sufficient to widen its orifice (a). Particular instruments have been also used for this purpose (b). This practice is, however, always tedious, painful, and can only in a few cases be effective. 1653. The two usual modes of operating for phimosis are circumcision and slitting up the prepuce, with or without removal of the flaps. If a congenital phimosis be distended by collection of the urine, it is sufficient to thrust in a lancet at the under and fore part of the prepuce, without injuring the glans, and then, after every discharge of urine, to insert a little plug into the aperture for a time. 1654. Circumcision {Circumcisio, Lat.; Beschneidung, Germ.; Cir- concision, Fr.) consists in the operator taking hold of the prepuce, above and below, with the thumb and forefinger of the left hand, so that their tips are about a line distant from the glans; an assistant draws back the outer fold of the prepuce, as far as possible, to the root of the penis, or compresses the glans with his thumb and finger; the operator then cuts off'that part of the prepuce which he holds with a stroke of the bistoury, but cautiously, that he do not injure the glans. The size of the piece to be removed must depend on the length of the prepuce, and on the extent * of its narrowing and thickening; too little, however, must not be removed, as, if so, the inflammation following the operation easily produces fresh narrowing. It is superfluous to hold the part to be cut off with a clamp, as recommended by some practitioners. If, as almost always happens, the outer fold of the prepuce be retracted further than the inner, the lat- ter must also be cut off to correspond. The bleeding, which is often considerable, must be stanched with cold water, with sponge, with con- tinued pressure, or if any single vessel spirt forth, it must be tied. Samuel Cooper and Wattmann recommend the connexion of the two folds with stitches. The Jewish circumcision differs in that after the child is wrapped from the shoulders to the pubes and from the middle of the thighs to the ankles in a cloth properly fastened and laid across the thighs of a sitting man, by whom he is pro- perly held, the circumcisor grasps the prepuce with the thumb and forefinger of his left hand, draws it forwards, and inserts it in the cleft of an instrument similar to a silver spatula. Thus holding the prepuce, and raising the penis upright, he cuts off the former close to the plate with a single stroke of a button-ended knife. The cir- cumcisor now, as quickly as possible, seizes the inner fold of the prepuce with his thumb-nails, which have been specially cut for the purpose, and tears it immediately up to the corona glandis. He then spirts some water from his mouth upon the wound, takes the penis in his mouth, and sucks the blood out of it a few times. A strip of fine linen is then wound round the corona and the cut surfaces, as a dressing, and the penis laid upon the pubes, in a ring to prevent it being touched (1). Terquem (c) speaks in favour of removing the inner layer of the prepuce, and has proposed an instrument like a pair of scissors (posihetome mobile) for the purpose. (a) Loder, above cited, p. 90. (c) Above cited. (6) Heister j Instit. Chirurg., pi. xxvi. f. 5. 56 TREATMENT fl) Many years ago I was present at a Jewish circumcision, and was so much struck with its facility and appropriateness to the purpose, that I have ever since performed the operation in the same manner, except that instead of inserting the pre- puce in the cleft spatula, I merely grasp it with a pair of dressing forceps, as close as possible to the glans, and then cut it off before them. The tearing up the inner part of the prepuce to the corona is a very important part of the operation, and far preferable to its division to that extent with the knife, as, whilst the inflammation ia subsiding, the cut edges, especially near the angle of the wound, are prone to adhere together, by quick union; and even if this do not extend far, it causes a girthing of the glans, which is inconvenient and often requires a second division to complete the cure. By tearing the inner skin, which should always be torn completely behind the corona, or the operation will be useless, the edges of the wound become sloughy, and disposition to quick union is prevented. From repeatedly having per- formed circumcision in this way, I am sure it is the best mode. And I may add, that, as regards circumcision or slitting up of the prepuce, the former is in every case much to be preferred. I never, however, put in any stitches, as they are not merely superfluous, but add to the necessary inflammation without sufficient reason. --J. F. S.] Upon the bleedings after circumcision, see, Goldmann (a). 1655. Slitting up the prepuce is performed in various ways, in doing which, however, it must always be remembered that the outer fold should first be well drawn back, so that, as far as possible, an equal division of both folds should be made. Through the orifice of the pre- puce is to be introduced Savksny's fistula-knife, or a knife specially for this operation {b), with its point guarded, and held flat, till it reach the middle of the corona glandis; it must then be turned on edge, and, by sinking the handle and raising the point, it is thrust through the skin, and then being drawn towards the operator, it divides the prepuce at a stroke. The flaps are to be grasped, one after the other, with the thumb and forefinger of the left hand, and cut off obliquely downwards and forwards with the curved scissors, along and close to the frcenum, or, if they be not too large, they may be left, and gradually shrink and retract. According to Cloquet's mode (c), a director should be intro- duced at the under part of the prepuce, parallel to the frcenum, and upon it the division made with the knife. If the frcenum be very short, it must also be divided with the scissors. The longitudinal wound be- comes transverse by the retraction of the prepuce, and heals without deformity. Covering the point of a narrow bistoury with wax, for the purpose of introducing it into the aperture of the prepuce, is unnecessary. Many persons in this operation use button-ended scissors; others introduce a director up to the corona glandis, and upon it a narrow-pointed bistoury, which they thrust through, after withdrawing the director, and divide the prepuce as just mentioned. If in consequence of the retraction not having been properly made, the external fold of the prepuce be insufficiently divided, it must be done with the scissors. If the narrowing of the prepuce be of that kind that slitting it up half way is sufficient, this must be done, and the flaps cut off obliquely from above downwards, or left to retract. In order to prevent the swelling of the flaps of the prepuce, which, by sewino- to- gether, causes that of the obtuse angled wound, Fricke (d) makes, after the divfsion ot both folds of the prepuce as already directed, a cut of the length of half an inch through the skin to the underlying cellular tissue, towards the root of the penis. (a) von Graefe und von Walther's (c) Bulletin des Science Medicales 182fi Journal, vol. iv. p. 284, vol. xiii. p. 201. June p. 206. ' ' (6) Guillemeau, Benj. Bell, Petit, and (d) Annal. der chirurg. Abth d?q Ham Latta, have proposed particular kinds of burger Krankenhauses, vol. ii. 256 knives for this operation. OF PHIMOSIS. 57 The division of the prepuce at the upper, middle, or under part, is always preferable to that on either side. Sometimes the narrowing of the prepuce depends on a hard ring, situated at its inner fold ; it is then sufficient to pass a narrow button-ended knife behind this ring, and to cut through it in withdrawing the knife. 1656. After the bleeding is stanched, the edges of the wound should be covered with lint, confined with sticking plaster, a small compress, and a narrow bandage, and the penis placed upright towards the belly. If inflammation ensue, cold applications are to be made; and in cedematous swelling and gangrene, warm ones. The dressings should be removed as often as necessary. 1657. Although circumcision of the prepuce is by many practitioners considered to have great advantages, especially when its aperture is narrowed merely by a hard ring, if the fore part of the prepuce be not only unnaturally narrow, but also thickened, relaxed, or to some extent contracted into a tube (a), yet by this treatment less of the inner than of the outer fold is cut off, and frequently so much less that the object of the operation is not attained, if the inner coat be not also either cut into or cut off; for which reasons the slitting up of the prepuce is, indeed, in general properly employed (b), and circumcision only in the simultaneous great degeneration of the prepuce, and then the inner fold must be also specially divided. It is also always most advisable to remove the flaps after slitting, as already mentioned, as they swell con- siderably after the operation, remain thick and misshapen, and render connexion painful, or prevent it, and only in children after the lapse of some years resume their proper size. This renders Cloquet's pro- posed operation superfluous. 1658. The operations in which not the whole thickness of the pre- puce, but specially only its inner fold, seem preferable to those already mentioned. The origin of congenital phimosis is not, as usually sup- posed, a narrowing of the two folds of the prepuce, but merely a want of extensibility in the inner one. The operation may therefore be most simply performed in the following way. The external skin of the penis should be retracted sufficiently far to discover the aperture of the pre- puce, into which a narrow-pointed bistoury, with its edge upwards, is to be introduced, or a pair of scissors, and some lines distant of both folds divided. With the fingers of the left hand the skin is much drawn back over the glans, which, thus somewhat uncovered, the slightly ex- tensible inner fold appears tightly stretched over the glans, and preventing the retraction of the prepuce. This inner fold is now to be divided either with the knife or scissors, as often as is necessary, till the prepuce is quite free upon the glans, and capable of being brought back- wards and forwards. The bleeding is of no consequence; the whole after treatment consists in repeatedly drawing back the skin over the glans and bathing the penis in cold water. In a few days the patient is cured without any mutilation. I have frequently performed this operation, with the best result (c). (a) Loder, above cited, p. 86.—Richter, ancient and modem mode of curing Dis- Anfang-sgrunde, vol. vi. p. 191. eases in the Urethra and Bladder, &c. Lon- (6) Zang ; Operationen, vol. iii.'pp. 34 and don, 1826. 8vo. Eighth Edition.—Fer- 40. A'ERi Note sur l'Operaiion du Phimosis (c) Foot, A critical Enquiry into the naturel; in Revue Medic, vol. viii. p. 305. Vol. iii.—6 58 TREATMENT 1DLa"0«bi« f*) ?SS3.^a riSilar Jay. though manifestly less simple and satisfactory! After an assistant has forcibly drawn back the general coverings, he ™Sp^ the edge of the prepuce with a pair of forceps, introduced within it and With fpah: of scissors makes some little snips at different parts, and so many of them, till the whole prepuce can be completely drawn back. After each snip the prepuce must be still drawn back, till it be everted and the inner fold come into view, in which he then makes the snips which may be still necessary. In old and hard pre- puce, with little extensibility of its inner fold, Begin (c) employs a practice whicB indeed is to be considered as a modified slitting of the prepuce already described. After previously slitting up the prepuce, he cuts off the corners of the flaps with scissors, so that ihe wound becomes round ; he then Tetracts the skm of the penis, and cuts off the inner fold of the prepuce, as far back as its base, with the sissors. The skin will soon draw together, and healing follows, a V-shaped scar being formed on the inner fold, by which its breadth is increased. According to Vidal de Cassis (d), the operator, whilst an assistant fixes the prepuce with a strong pair of forceps, from above downwards, passes through the prepuce, below the forceps, three transverse threads, and a fourth vertically from before backwards ; then with strong scissors he cuts off the prepuce in front of the forceps, avoiding the threads. The forceps being then removed, the glans is partially exposed with the threads over it. The middle of each thread is now taken hold of with forceps, and being drawn a little forwards, four loops, are made, each of which being cut through, eight sutures are formed, which after just sufficiently cutting through the inner fold of the prepuce strongly retracted are tied, and thus the edges of the outer and inner fold of ihe pre- puce brought into contact. 1659. If the prepuce be united to the glans, after that it has been cut into where not united, the connexion must be separated with the spatula, the scissors, or the knife; but if their junction be so complete that no instrument can be introduced between the glans and the prepuce a cut is to be made carefully lengthways through the prepuce without injuring the glans, and then it must be ^attempted by lengthening the cut upon the director or by careful dissection, in which the knife is to be always more towards the prepuce than the glans, to separate the connexion and remove the divided flaps. In all cases where the union is close and firm, where no instrument can be introduced between the glans and prepuce, the operation is excessively painful and difficult, and the result rarely corresponds to the expectation (e). In such cases therefore the prac- titioner should be content, if the patient do not urge the more extended operation, to cut into the aperture of the prepuce so far. and so to enlarge it by the introduction of bougies that a free escape of the urine may be effected. 1660. When the connexion of the glans with the prepuce by bands is such that many functions of the penis are interfered with, the opera- tor holding the glans with the thumb and forefinger of the left hand, whilst an assistant draws down and stretches the prepuce near the bands, introduces a narrow curved knife through the bottom of the tri- angular fold of skin forming the freenum, and draws it out. Lint 1822.—Chelius, Ueber Phimosis und Para- (c) Nouveauv Elemens de Chirurgie, vol. phimosis; in Heidelb. kin. Annal, vol. iv. ii. p. 550. Second Edition. PM^" p„,m„ u •. , ie, for the purpose of gradually dilating the stricture, beginning with one of a smafl size, and gradually proceeding to those which are larger. Sometimes you will find it best to introduce the sound without turning, that is, with the concavity towards the patient's abdomen; at other times, you will pass it more readily by keeping the handle in the first instance, towards the patient's left groin, turning the instrument afterwards as it approaches the stricture. In either case, if you wish to avoid making a false passage, take care that the point is kept sliding, as it were, against the upper part of the urethra. Press the instrument firmly, but gently, against the stricture in the expectation that it will gradually become dilated and allow the point to enter- then depress the handle, and pass it into the bladder, provided that you can do so readilv and without the application of force, but not otherwise. Two or three days after STRICTURE OF THE URETHRA. 73 wards, (and the interval ought to be never less than this, and sometimes it ought to be greater,) introduce the sound which has been passed before, withdraw it, and introduce another of a size larger; and thus go on dilating the stricture until that part of the urethra has regained its natural diameter. - If in the course of these pro- ceedings you are in doubt whether the sound has reached the bladder or not, you may easily determine the point in question by introducing a catheter. You might, indeed, use the catheter from the beginning, but that the openings near the point, and its comparative lightness, render the introduction of it less easy than that of the solid instrument. This method of treatment is applicable to a large proportion of the cases which you will meet with in practice: first, to those of old and indurated strictures, which the common bougie is incapable of dilating; secondly, to those in which, in consequence of some improper management, a false passage has been formed, into which the point of a common bougie will easily penetrate, but which an inflexible instrument may be made to avoid; thirdly, to those in which, from long-continued disease, and without any previous mismanagement, the urethra has become distorted and its surface irregular; and,fourthly, to several recent cases, in which the smooth, polished surface gives less pain to the urethra, and is less likely to induce spasm, than the softer, but less smooth surface of a common bougie, (p. 51—4.) "In treating a stricture of the urethra with the gum catheter, you are to introduce it and allow it to remain day and night in the urethra and bladder. If the patient can bear it to be retained for a sufficient length of time, the stricture will become dilated not only to the size of the instrument employed, but to a size considerably larger. Perhaps you will be able to introduce the catheter without the wire or stilette. Do so, if possible. If not, you should employ one mounted on a strong, un- yielding iron stilette, having a flattened handle, like that of a common sound or staff. Being so mounted, it is more readily directed into the bladder than when mounted in the usual way on a piece of thin flexible wire. When the gum catheter has entered the bladder, withdraw the stilette, and leave the catheter with a wooden peg in its orifice, which the patient is to take out whenever he has occasion to void his urine, it being at the same time secured by a suitable bandage. After three or four days, you may withdraw the catheter for twelve hours ; or, if much suppuration be induced in the urethra, you may withdraw it for a longer period. Then introduce another catheter, larger than the first; and thus you may, in the course of ten days or a fort-night, dilate a very contracted urethraKto its full diameter. This is a very certain and expeditious method of curing a stricture. You may by these means sometimes accomplish as much in the course of ten days as you would accomplish in three months by the occasional introduction of the bougie. This method is particularly applicable,y»-s/, where time is of much value, and it is of great consequence for the patient to obtain a cure as soon as possible; secondly, where a stricture is gristly and cartilaginous, and therefore not readily dilated by ordinary methods; thirdly, where, from the long continuance of the disease, the urethra has become irregular in shape, or where a false passage has been made by previous mismanagement. Under these circumstances, if you can succeed in introducing a gum catheter, and let it remain for a few days in the bladder, you will find your difficulties at an end ; the irregu- larities will disappear, and the false passages will heal; fourthly, there is still another class of cases in which this method of treatment is particularly useful. I allude to those in which a severe rigour follows each introduction of the bougie. This disposition to rigour is such, that it is sometimes impossible to proceed with the treatment in the ordinary way. Observe, in these cases, when the rigour takes place. It seldom follows the use of the bougie immediately. It almost always occurs soon after the patient has voided his urine, and seems to arise not as the im- mediate effect of the operation, but in consequence of the urine flowing through the part which the bougie has dilated. Now, if instead of a bougie you use a gum catheter, and allow it to remain, the urine flowing through the catheter, the contact of it with the urethra is prevented, and the rigour is prevented also. I have no right to say that this plan will invariably succeed, but I do not remember that it failed in a single case among many in which I have resorted to it." (p. 57-9.) Although the harmlessness of plaster bougies is asserted by the high authority just quoted, yet I cannot accord with that statement, for I am quite sure that they are very frequently exceedingly mischievous, and that, even with the greatest cau- tion, much injury may be done by their frequently slipping from the stricture and 74 TREATMENT OF perforating the wall of the urethra in front of it, and P^«^» ^S^XNfi not very uncommonly laying the foundation for urinary ^scess and fistula^ I He quickness with which they often soften by the mere beat of the ^J "° ^JJ *£ that it is almost impossible to be sure of the precise quantity of p essur> which they will bear- and when they once begin to yield, they speedily curl and twist in a very JSorfii J manner near their tip, and, though they may not actually pene- trate the watl of ythe urethra, yet they may seriously damage it by their increased bulk at this part, as the curve assumes the shape of a corkscrew to a less or greater extent. I Tiave known bougies pushed through the urethra again and again, and false passages formed whilst the surgeon supposed he was making progress in the cure of the stricture, when, in reality he was making matters worse. Ihere are, 1 apprehend, more false passages made with them than with any other instrument, and few Museums are without examples of such results. I therefore have long since almost entirely given up using bougies, and prefer a catheter or a sound, as with either of these the precise quantity of pressure made, as well as the actual course which the point of the instrument takes, is more readily ascertained, and l it be inclined to go wrong can be more easily and satisfactorily corrected. And with them there is little or no excuse for tearing the urethra. In addition to which, experience shows, that the smoother surface of the metallic instrument greatly favours its movement along the urethra, and that its tip will often, without difficulty, overcome any little spasm about the stricture, and pass through it, when it is im- possible to make a bougie move on without mischief. 1 do not think it of much consequence whether a catheter or a sound be used; perhaps the former has the advantage of showing at once its entrance into the bladder, by the flow of urine through it, whilst the latter, on the whole, passes more readily, and with less resistance, as its own weight gently urges it on, if it be only kept in the proper direction. A silver sound is preferable to a steel one, as most practitioners who have been in the habit of using it will bear testimony ; but it should be solid silver, and not, as is too commonly the case, merely a silver catheter filled with composi- tion, which is not only less weighty than the solid one, but is liable to be broken in two if it be necessary to make any alteration in its curve, as is not unfrequently requisite, to adapt it to the particular case. I think, also, the conical fonn recom- mended by Astley Cooper is highly advantageous, and of the best which can be used. A couple of them is amply sufficient for any surgeon's armamentarium, of which the point of one should be that of No. 3 or 4, and of the other that of No. 5, increasing in size upwards to Nos. 10 and 12 respectively. Some practitioners are in the habit of using a straight sound like a skewer, with a conical point; but if the stricture be in the membranous part of the urethra, it is a very dangerous instrument in the hands of most persons, and not adapted, I think, for general use. The excellent directions given by Brodie for the introduction of the sound or catheter leave little to be added. The importance of avoiding all violence cannot be too strongly urged. An instrument to be passed into the bladder should rather, as Abernethy used to say, be "coaxed," not forced. There are, howeveT, other two points which must be carefully attended to in this operation; the urethra may fall into folds, either in its length, or in its transverse diameter, in consequence of which the point of the instrument becomes entangled, and will be at once stopped, and may or may not be thrust through the side of the canal, although at the part where the hitch is, no stricture exists. The urethra folds lengthways, when the instrument does not completely fill it, for which reason it is always advantageous to introduce such an one as nearly of the size of the urethra, as will have a chance of its point entering the stricture; and I am convinced that there are few strictures in which it will be necessary to commence operations with one smaller than No. 6 or No. 4; provided the cure only of the stricture is considered, and not the immediate relief of the bladder from retention of urine, in which case a small instrument is admissible. But small catheters or sounds are at all times very dangerous, except in more dex terous hands than those by which they are commonly used; and, as they more quickly slip through the wall of the urethra than larger ones, the patient's condition is rendered worse than before, because it often becomes necessary to suspend the use of instruments, if luckily the accident should be discovered, which is far from com- monly the case, till the tear has healed up, even if it do not give opportunity for the escape of the urine, and so give rise to abscess. The transverse folding of the urethra roost commonly occurs in the membranous part, and may happen whether STRICTURE OF THE URETHRA. 75 the instrument be small or large, and the obstruction thus produced very frequently leads to the presumption of a stricture when none really exists. This transverse folding depends on the gent's and urethra not being sufficiently drawn forward upon the instrument; so that, when the handle of the instrument is depressed to tilt the point up behind the suspensory ligament into the bladder, the point lifts with it the lax urethra in front of it, and, doubling it, from a valve which blocks its further pro- gress. Attention to keeping the whole length of the urethra stretched will generally prevent this, or it may be corrected by elevating the handle of the instrument so that the point disentangles itself, and will then pass on without hindrance. The point of the instrument is also not unfrequently stopped, by depressing the handle too early, that is, before it has completely entered the membranous part of the urethra, in which case it strikes against the front of the suspensory ligament, and will not pass further. The greatest care must therefore be taken that the instrument has passed well beyond the ligament before the handle is depressed 'and the point tilted up; and if then it will not enter the bladder without much difficulty, it is better to pass the finger into the rectum, and the end of the instrument being felt, it is in general easily directed into its proper course, and little risk encountered of thrusting it through the urethra between the bladder and pubes, or between the bladder and rectum, which, especially the latter, is of not unfrequent occurence in not very prac- tised hands. When the instrument has entered the bladder, its point can usually be freely moved in any direction; but when it will not move but forward after its handle is depressed, it is pretty certain it is not in the bladder but in a false passage, and must be withdrawn, and fresh attempts made to carry it in the proper direction, instead of thrusting about and doing serious mischief. The frequency of intro- ducing the instrument must vary according to the irritability of the urethra; in some cases it cannot be used more than once a week at first, as it will frequently produce severe irritation in the passage, and be followed by shivering, and occasionally a hot fit afterwards, and it may be necessary to defer the second introduction for even a still longer period. But if no febrile excitement follow, it may be introduced every third or second day, which is generally often enough. It is also very advantageous to bathe the perinaeum night and morning with warm water, and even immediately after the introduction of the instrument, if it have caused much irritation; and if there be continuing pain, it is best to apply a few leeches. Going into a warm bath twice a week, and the use of leeches to the perinaeum as frequently, if the stricture be very obstinate, will be often found to assist very materially in hastening the in- troduction of the instrument, and the widening of the stricture. If the patient be desirous of keeping the passage free, he should persevere in passing a large bougie once a fortnight, long after the cure appears to have been effected, as there is always great tendency to its recontraclion. Some surgeons consider the introduction of a bougie is rendered more easy, by having its tip smeared with extract of belladonna. I have tried this plan, but I think not with much advantage. If any benefit be gained from it, it will not be immediate; the bougie thus smeared must be passed down to the stricture, and left in some hours, after which it must be withdrawn, and another introduced. It may, however, be doubted whether the mere residence of the bougie in the urethra has not more to do with the relief than the operation of the belladonna ; for occasionally a bougie thus managed, as recommended by some French surgeons, will facilitate the introduction of an instrument which previously would not enter the stricture. I do not like cat-gut, nor elastic gum-bougies; they are tough enough to do mischief, but not sufficiently firm to enable us to judge of the pressure made with them, nor to guide them properly. I cannot say that my experience, as regards the wearing a gum elastic catheter for the cure of the stricture, has been so successful as Brodie has found it. Frequently the irritation set up by it in both urethra and bladder has been so great as to compel its removal; and, although I think wearing a silver catheter is more easily borne, if the patient be kept in bed, which, under either mode of treatment, I have always found necessary to enjoin, yet even then I have known in one instance a slough of the urethra take place in front of the scrotum, without warning, in the course of a few hours; so that, although the case has seemed to be going on well at one visit, on the following day the first step towards a certain aperture in the urethra has been made.—j. f. s.] 1684. The time which the bougie should remain in the urethra must 76 TREATMENT OF especially depend on the sensibility of the patient in general, and of the urethra in particular. It must be so managed that the patient shall suffer as little pain as possible. The bougie should, therefore, remain only til] the patient complains of pain, which on the first day does not exceed a quarter or half an hour, but in an irritable urethra not longer than a few minutes. The introduction must be repeated about every other or every day. If the bougie be left in longer, severe pain, swelling of the testicles, febrile symptoms, and abscesses near the urethra, often occur. The use of the bougie must then be suspended for a long time, and the inflam- matory condition got rid of by blood-letting, quietude, warm-bathing, and antiphlogistic diet. Many writers have, however, advised that the bougie should remain for several days, in consequence of which an increased secretion of mucus in the urethra is excited, its sensibility blunted, and it is protected against the presence of foreign bodies (a) For the most part, patients soon become accustomed to the longer resting of the bougie in the urethra, and after some days it may be left. It is then advisable to exchange it for an elastic catheter, which is specially indicated, if there be already fistulous openings, because the patient is thereby relieved from the necessity of its frequent removal, and re-introduction, for the purpose of discharging his urine. The bougie, or catheter, when left in, should be properly fastened; a tape must be bound tightly round it at the mouth of the urethra, the ends of which, carried over the glans penis, must be fastened behind it with several turns of sticking plaster, and the loose ends tied together. This mode of fastening is simple, safe, without difficulty, and preferable to fastening a thread to a ring placed upon the penis. (Dupuytren.) When the bougie has been long left in, it often, especially at first, acquires an indent from the stricture, in consequence of which, if it be carelessly withdrawn, violent pain may be produced. This may be prevented, if the bougie be frequently moved, and gently drawn up and down. 1685. Thin bougies, or catheters, should be gradually exchanged for thicker ones, which, in not very tough strictures, may be soon; and this should be repeated till the urine is voided in its accustomed stream. The bougie must not be left off at once, but must still be left in for some time every day, or every other day, and afterwards every week for some hours. It will be also advantageous in dispersing the hardness of the membranes of the urethra to apply, externally, mercurial ointment, and to give, in- ternally, cherry bay water (b) and the like. If, afterwards, the stream of urine should begin to diminish, and the patient have difficulty in passing it, the use of the bougie must again be prescribed. In order to effect the expansion of the stricture at pleasure, Arnott (c) has pro- posed an instrument, consisting of an oiled silk tube, which, for the purpose of rendering it air-tight, is lined with the thin gut of some small animal, and connected with another tube, through which air can be blown, or water injected by means of a syringe, and retained by a cock. Although the introduction of this instrument is generally as easy as that of a bougie, it is, however, frequently, better, especially in an irritable urethra, to introduce it through a cannla. When it has penetrated the (a) Desault, Chopart, Delpech, PrecisElementaire, vol. i. p 55ft (6) Riohter, Anfangsgrilnde, vol. vi. p. 283. (c) Above cited, p. 92. STRICTURE OF THE URETHRA. 77 stricture, it is to be filled with air or water, as long as the patient can bear it with- out pain. [Conundrums of this sort are very well pour s'amuser, but every practical person will be very well aware that if a stricture will admit such a contrivance it is suf- ficiently expanded not to require the assistance of a surgeon, or any one else, but had- better be left alone.—j. f. s.] 1686. The operation of bougies consists in the expansion, compression, and irritation, produced by their introduction and inlying, in consequence of which an increased secretion of mucus, and modification of the vitality and condition of the diseasedly changed mucous membrane is set up. In common cases their presence in the urethra excites only a little pain and mucous discharge ; but in sensitive persons, violent pain and inflamma- tion, painful erections, transition of the inflammation to the testicles, and swelling of the inguinal glands, will be produced with the inlying of the bougie; also inflammation of the cellular tissue upon the outer surface of the urethra, terminating in suppuration and extravasation of the urine. All these symptoms require, besides the removal of the bougie, an anti- phlogistic treatment corresponding to circumstances, blood-letting, spare diet, luke-warm bathing, and the like. If, during the use of the bougie, an abscess form, with severe pain increased on pressure, Desault {a) advises the introduction of an elastic catheter, not to open the abscess, but to let it burst of itself, or, if it empty into the urethra, to let the pus escape by the catheter; but if it be then necessary, on account of the great size of the abscess, to open it, then always to make a small open- ing, as a large aperture retards the cure. Although, however, I have in several instances pursued this treatment successfully, yet it appears better, on account of the danger from extravasation of urine, in these case's, as soon as inflammation shows itself, to remove the bougie, and to employ active antiphlogistic treatment by general and local blood-letting, bathing, softening poultices, rubbing in mercurial ointment, and the like, and if fluctuation should show itself, by early opening the abscess {b). [Astley Cooper adverts to the not unfrequent circumstances of bleeding from the urethra after the introduction of the bougie; or, it may be added, of a sound or catheter which has been roughly handled, or after the use of a caustic bougie. He says:—"The passing of a bougie is often attended with very considerable haemor- rhage from the urethra," and mentions a case in which he " pressed a roller upon the perinaeum, which instantly checked the flow of blood. A short time after he was sent for to the same patient, the haemorrhage having returned; he had,been loung- ing before the fire with a foot on each side of the chimney-place; the warmth coming in contact with the perinaeum had brought on a renewal of the haemorrhage. He made an incision on the part, and divided the artery of the bulb ; this operation completely succeeded, and the bleeding was permanently subdued." (p. 225.) I apprehend the necessity for such active treatment is rare, at least I have never seen any need for it, and believe that Abernethy's mode of proceeding (c) is amply sufficient in most cases. "When haemorrhage occurs it is best," he says, "to put the penis in a tumbler, so that the quantity of. blood may be evident. I cover the feet and upper part of the body with the bed-clothes, leaving the pelvis bare; I then wash the perinaeum with vinegar and water. The vessels of the urethra speedily contract, and the bleeding stops. I would recommend you to do these things your- self, and not to trust to the patient or his attendant." Astley Cooper also gives the following advice, which, if followed, will often save the patient much suffering:—" Whenever you suspect a tear of the urethra in passing a bougie, immediately withdraw the instrument, and desire the patient, if (a) Above cited, p. 252. (b) Docamp, above cited, p. 87. (c) MS. Lectures. 78 TREATMENT OF possible, to retain his urine, that it may not irritate the wound, and also to prevent its escapino- through the opening and becoming extravasated in the surrounding cellular substance. In this way you give time for a clot of blood to form over the surface of the wound, a slight degree of inflammation is excited, and it becomes healed by the adhesive process without any further mischief." (p. 225.) To this I would add that, under such circumstances, it is advisable that no attempt should be made to introduce the instrument again for several days, and that it should then be done with a very light hand, and with great care.—jr. f. s.] 1687. The destruction of stricture by caustic is effected either with nitrate of silver or caustic potash. 'The application of both these remedies varies, according as the cauterization is made upon the stricture from before backwards, or on its walls in the narrowed part itself. The destruction of strictures by ulceration, in which very hard bougies are violently inserted in the stricture, so that they are grasped by it, in order to produce com- pression and ulceration of their walls, is to be completely rejected as dangerous and unsafe. [Brodie says:—"I am much mistaken if a stricture is not sometimes destroyed, at least in part, by ulceration. For example: I attended a. gentleman who had laboured under a stricture of the urethra for a great many years. He voided his urine with the greatest difficulty, the stricture being very rigid and unyielding; but I succeeded in introducing a cat-gut bougie, and this enabled him to make water in a small stream. Under these circumstances he was seized with pain in the act of making water, which lasted for some minutes afterwards, being referred to the situation of the stricture in the posterior part of the urethra. The pain became more severe, and the patient described it to be intolerable, saying that he could compare it to nothing but the sensations which he supposed would be produced if melted lead had been poured into the canal. Every half hour he had a desire to make water, and his groans might be beard, not only through the whole house, but even in the street. In the; course of a few days these symptoms began gradually to abate, and now it was discovered that the urine flowed in a much larger stream. When the attack had completely subsided, the condition of the patient was much improved, and he made water more easily than he had done for many years." (p. 15.)] 1688. In cauterizing a stricture from before baclcwards, a common bougie is to be first carried down to the stricture, for the purpose of open- ing the canal of the urethra, and the distance-frorn the orifice of the canal must be marked close to it on the bougie. This having been withdrawn, a corresponding mark is to be made on a bougie armed with lunar caustic, which, after having been properly oiled, must be carried down the urethra to the stricture, against which it must be moderately pressed, and accord- ~ ing to the patient's feelings, for a different length of time, though on the first day not for a minute. In this way the armed bougie is employed every other day, or in obstinate cases, daily. When ihe slough has been thrown off, an elastic bougie is to be introduced, and thus gradually the natural calibre of the urethra is restored. Bougies armed with lunar caustic are made in the following way:—In forming the common bougie a piece of wire is rolled into it, extending about half an inch into its substance. When the bougie is nearly completed, the wire must he pulled out, and a piece of lunar caustic inserted in its place. The bougie is to be then again rolled, so that the sides of the caustic may be firmly surrounded with the linen, which gives a blunt end to the bougie. Hunter (a) used, for applying the caustic, a flexible silver catheter, provided with a stilette, which had at its extremity a portcrayon for holding the caustic. [In the directions which Hunter gives for the introduction of the caustic, he mentions, it is necessary for the canula to be furnished with a piece of silver or a stilette, having a button at one end, forming a kind of plug, which should project {a) Above cited, p. 139. STRICTURE OF THE URETHRA. 79 oeyond the end of the canula, and give it a rounded end, to facilitate its passage along the urethra to the stricture, having reached which the plug is withdrawn, and the portcrayon, which may be attached to the other end of the stilette, introduced in its stead. This apparatus was, however, a very bungling contrivance, and Hunter doubtless found it so, for Home mentions in a note, " that before his death Mr. Hunter left off entirely the use ofthe silver canula, and used the lunar caustic inserted into the end of a common bougie," (p. 140,) the mode in which it is now, whenever employed. The great advocate for the treatment with lunar caustic was Home ; but it was soon fiercely and efficiently attacked by Whately, who showed the mischievous and dangerous results ensuing from it; for, to use Lawrence's words, " if we are to credit the description which Home gives, nothing would be more safe or effectual than this mode of treatment. When we come, however, to peruse the cases he gives in illustration of the various points of the treatment, we find that serious mischief is sometimes produced by this mode of treating stricture; and as he (Home) is highly favourable to the plan, we may at all events suppose that he is not exaggerated the ill-effects of the treatment." [p. 802.)] 1689. This mode of cauterization has considerable objection, as espe- cially in strictures behind the curve of the urethra, the walls are easily destroyed, false passages made, and considerable bleedings produced. Not unfrequently the aperture of the stricture is closed by the thick slough, and complete obstruction to the voidance of the urine produced: and farther, by the hard, formless scar which is produced, the disease again returns more severely than at first. , 1690. It is attempted to overcome the greater number of these dis- advantages by cauterizing the walls of the stricture. According to Arnott (a), after the seat and condition of the stricture have been ascer- tained by careful examination, and with a very soft bougie, which should be introduced through a canula, and take every impression of the stric- ture, a pretty large canula should be carried down to the stricture. A piece of lunar caustic, somewhat smaller than the stricture, should then be pierced through its middle with a metal stilette, and upon which it must be retained, half an inch from the tip, so that the stilette may be surrounded with a piece of common bougie, both in front and behind the caustic. The stilette is then passed through the canula down to the stricture, and through it, so that the caustic can be applied to any part of the stricture. When the caustic has been properly used, a small wad of linen is to be introduced by means of the same stilette and canula, to sop up all the caustic which has become fluid. [It must not be supposed, as Chelius would seem to infer, that Dr. Arnott is the original proposer of the treatment of cauterizing the walls of the stricture with lunar caustic; for Whately, in his Observations on Mr. Home's Treatment of Stric- tures, d>c, published in 1801, eighteen years before the first edition of Arnott's book on Stricture, had mentioned among the advantages of his construction of caustic bougies, by gluing the end of the instrument, and applying it to a given quantity of powdered lunar caustic, that " in the first place, the bougie may be of any size, even the smallest size can by this method become the vehicle of this powerful remedy; and may be readily passed into, or a little beyond such strictures as are extremely narrow,- or such as are attended with considerable contraction of the orifice of the urethra." (p. 68.) And again :—" If the stricture be open enough to admit a bougie of moderate size, such a bougie armed with caustic may very readily be passed into or beyond it." (p. 72.) Perhaps Dr. Arnott was unaware of Whately's observations, for it is rather curious, that although Hunter, Home, Astley Cooper, Lallemand, Ducamp, and other writers on stricture are mentioned by him, the only notice taken of Whately is, that a naval captain had obtained considerable relief under his care; and that after his death the captain's stricture having returned, he placed himself (a) Above cited, p. 157. 80 TREATMENT OF under the care of other surgeons, but without receiving much benefit from their Jjr. ARNOTT S new merauu 10 F'^'-"J -- . ~~ ----. , ^, -■ .. . V° the lunar caustic, and which he gave up as inefficient, with the exception that the caustic is held on a piece of wire, by which it is pierced, instead of a portcrayon, as in Hunter's mode; and with the important addition, that the stilette of the plug, instead of having the portcrayon attached to the other end, as recommended by Hunter, has "a little dossil of lint fixed on it, which is introduced before the caustic, to absorb any superfluous moisture in the stricture, and after it again, to take up any dissolved caustic which might spread in the canal." (p. 158.) From the above extracts it appears that the proposal of cauterizing the interior of the stricture, whether of much value or little, is Whately's and not Arnott's ; nor the new method other than John Hunter's old and disbanded one, with the addition of a wipe.—j. f. s.] 1691. If caustic potash be used for cauterizing the walls of the stric- ture, a bougie of sufficient thickness to enter the stricture with difficulty must be chosen, and passed down to it. A mark is then made on the bougie with the nail, half an inch from the orifice of the urethra, and when it has been withdrawn, a little cavity about the twelfth of an inch deep must be made in its rounded end, into which a small piece of caustic, less than the smallest pin's head, must be put, and so pressed in that the edge of the cavity project a little beyond it. To fix the caustic, the bougie must be squeezed together with the fingers, and the inter- space filled with lard. Thus armed, and after having been well oiled, the bougie is carried down the urethra to the stricture, where it is to he held till the caustic begin to become fluid, and the patient feels a burning pain. It is then to be introduced a quarter of an inch farther into the stricture, held there about a couple of seconds, and then passed a little further, till by a peculiar feel, or by the approach of the nail-mark to the lips of the urethra, it appears that the bougie has penetrated the stricture. If no pain occur, the bougie should be introduced once or twice a day!; but if there be pain, it must not be used. The whole operation should not exceed two minutes. Generally after the first use of the caustic there is but little pain, a slight cutting in making water, and its discharge in drops during the first few days. The bougie used should correspond to the diameter of the stricture, the caustic repeated after every eight days, and the bougie increased in size till the natural size of the urethra is attained. [The use of caustic potash in the treatment of stricture, was also first practised by Whately (a). "It has, however," says he, "been my good fortune to discover a more efficacious, and, at the same time, a less painful and hazardous remedy (than lunar caustic) for the disease in question. This valuable remedy is the kalipurum, which, if used in the manner, and with the precautions shortly to be described, will be found of singular efficacy in removing the complaint." (p. 23.) The directions for preparing.the bougie, and its mode of use, are those above given by Chelii's. Upon this mode of treatment Lawrence observes:—" Mr. Whately seems to have been as cautious in the employment of this substance, as Sir Everard Home was bold m his use of lunar caustic, for he recommends you to take a fragment of potasm fusa, not larger than the seventeenth part of a grain. And he says he never used a portion larger than the twelfth of a grain. * * * I should conceive, according to the description Mr. Whately has given of it, that it is just capable of doing that good which the simple introduction of a plain bougie can effect; and I cannot think it had any effect whatever as an escharotic." (p. 802.)] (a) An improved Method, &c., above cited. STRICTURE OF THE URETHRA. SI 1692. Although these two modes of cauterizing the interior of the stricture have considerable advantage over that of cauterizing from before backwards, yet they have little certainty in practice, and in many respects are deficient, especially the caustic potash. Ducamp has the great credit of having proposed a method of cauterization and destruction of stricture, which is distinguished from all the previous modes by its accuracy and certainty. 1693. According to Ducamp's method, the seat of the stricture is first found with a bougie or sound, and the situation and condition of its aperture ascertained by an exploration-sound, the end of which is covered with modelling wax, which being gently, but steadily pressed against the obstacle, a perfect impress of the stricture is obtained. Its length is also determined by a thin bougie, with a little bulb, and covered with modelling wax, which is fastened to a thicker conductor. For this pur- pose Charles Bell has recommended a thin metallic sound with a but- ton, Arnott a thin tube, with a very short leather button, and Amussat (a) an explorer. For this object Ducamp has proposed a peculiar instru- ment, which, however, does not appear suitable. It is oftentimes neces- sary, to enlarge somewhat the very narrow opening of the stricture by gradually thicker bougies, wThich may be left in half an hour. 1694. The cauterization is performed with a cautic-holder, which, being properly oiled, is carried down to the obstacle, and then its inner shaft made to describe a half circle, is protruded into the stricture. For the purpose of cauterizing the whole surface, the instrument is gently turned on its axis. After a minute the inner shaft is to be drawn back into the canula, and the instrument taken out. If the ridge formed by the stricture be at the upper or under part, or on either side of the urethra, which is shown by the impression on the exploration sound, the caustic must be directed to that spot. A small piece of lunar caustic is to be put into the inner shaft of the caustic- holder, and the flame of a wax taper directed upon it with a blow-pipe; the caustic soon melts, and completely fills the whole groove. The heat must not be too great, or it will swell up the caustic; it must only be sufficient to fuse it. If any points project, they must be removed with pumice stone. The groove will hold about half a grain of lunar caustic, and, if the instrument be kept in not longer than a minute, about one-third of it will dissolve. As by this method the caustic will be easily too much swollen up, and little remain in the groove, Hahn, according to Berg, proposes the following method :—Some powdered lunar caustic, from six to twenty grains, is to be moistened with water in a little porphyry dish, boiled up over a spirit-lamp, and constantly stirred with a silver knife till the water have evaporated, and the caustic remain fluid in its water of crystallization alone, which may be ascertained by its thin pap-like appearance, and the formation of the crystal- lization-film. This paste is now to be spread with the spatula on the slightly- heated groove of the shaft, and, when it has cooled, any projection is to be removed with the spatula, or with pumice stone. Whilst boiling, the caustic flies about smartly, and therefore it is necessary to put on a glove, so that the hand be not spotted with black. 1695. If there be only a single stricture, the patient feels, on the day of cauterization, little pain, but without passing his water in a larger stream; on the third day the slough separates, and the stream is then increased. The pain caused by the cauterization is scarcely more than that produced by the introduction of a common bougie. No inflamma- Vol. in.—8 (a) Above cited, pi. i. S2 TREATMENT OF tion occurs; very rarely a discharge, and, if previously existing, it is stopped. . -vi 1696. After three days a new impression is to be taken with the ex- ploring sound, which shows how much the opening has increased, and what part still projects, and must be destroyed. A moderate-sized bougie must then be passed and carried into the bladder, to ascertain that there is not another stricture.1 The caustic is now again to be applied as before, and at the most prominent part. Three days after a third impression is to be taken, and if the parts forming the obstacle project little, and a bougie, No. 6, can be passed with ease, the enlarge- ment of the canal has commenced. If there be still any prominence, or if the bougie pass with difficulty, the caustic must be applied a third time. If there be a second or third stricture, it is to be attacked in one or other of these ways. 1697. For the purpose of keeping the scar as wide as the urethra in its natural state, Ducamp employs peculiar dilators, and bellied bougies {bougies a ventre.) Three days after the last cauterization, a dilator of three lines diameter is introduced, inflated with air, and left in not longer than five minutes. Next day the same dilator is passed, expanded with air or water, and after ten minutes withdrawn and replaced by a bougie of two and a half lines diameter, which is left in for twenty minutes. This bougie is to be introduced for the same time next morning and evening. On the following day a dilator of four lines diameter is to be passed, withdrawn after ten minutes, and replaced by a bougie of three lines, which also, on next morning and evening, is to be left in from fifteen to twenty minutes. Two days after a dilator of four and a half lines is introduced, and afterwards a bougie of four lines morning and evening, each time for a quarter of an hour. After thus proceeding for a week, the bougie is only to be passed once a day, and allowed to remain for a few minutes ; for the following four or five, the bougie is to be introduced once daily, and withdrawn immediately. The scar is then well consolidated, and is four lines in width, as in the rest of the urethral canal. Ducamp (a). Dubouchet (b) thinks that the bellied bougies, will do as well as the dilators; and, indeed, experience proves it to be so. 1698. Ducamp cautions against the application of caustic when the urethra is inflamed ; that in long strictures it is best to destroy them bit by bit, by applying it only for two or three lines, as a longer slough separates with more difficulty, and the canal may be stopped up. If the stricture be six inches distant from the orifice of the urethra, a curved caustic-holder should be employed. As Ducamp's instrument will admit of no twisting, and as, on account of the different dimensions of the urethra, the cauterization, even up to six inches, cannot always be performed without danger of making a false passage, so Lallemand, Amussat, Segalas, and Tanchou have proposed modified caustic- holders, which may be introduced into the stricture with greater cer- tainty. b For the enlargement of very narrow strictures, Lallemand uses catgut. As the use of the exploring bougie, with however great care, in many instances'produces (a) Above cited pi. i. to iv.—F*orikp, (b) Nouveau Traite des Retentions d'Urine, Chirurgische Kupfertaf., pi. lxxxi. p. 206. Paris, 1834. 8vo. STRICTURE OF THE URETHRA. 83 great pain, and often much bleeding, and some of the wax may get loose, and by stopping up the canal cause retention of urine, Lallemand, if the impression of the stricture be not absolutely necessary, introduces a bougie smeared with wax into the stricture, which, after same time being withdrawn, by the pressure it has suffered, shows the length and even the situation of the obstacle. By the caustic bougie a second and third stricture may be attacked before the first is perfectly removed. Ducamp says that caustic should not longer be employed after a bougie No. 6 passes easily over the obstacle. Lallemand's experience shows that in such cases it is better to cauterize again, than to persist in the enlargement, if changing to a larger sound cause pain. Lallemand does not agree with Ducamp in destroying long strictures bit by bit, but advises cauterizing their whole length at once, as he has never noticed complete retention of urine in such case, nor even in that of deeper strictures from the separation of the sloughs; and, even should it occur, it might be easily relieved by the introduction of a bougie. Lallemand considers the subse- quent widening of the urethra by dilators useless; the bellied bougies will not easily take the necessary bend so as to be carried over the crooked urethra, which how- ever I must, from experience, contradict. Elastic curved sounds or bougies are most effective, which should be left in for fifteen or twenty minutes, and should not go beyond the width of Nos. 11 and 12, as if they pass, we may be quite sure of a successful result. Amussat employs both straight and curved caustic-holders (a). Segalas' caustic holder is distinguished by its introduction, covered, into the stricture. It consists of a graduated gum elastic catheter, in which a canula serves the purpose of sheathing the stilette of the caustic-holder, which, with its olive- shaped button, fits close to the mouth of the canula. The instrument is passed down to the stricture, then the canula carried down it, and, being withdrawn, leaves the caustic-holder uncovered in the stricture. Tanchou's caustic-holder, by means of a projecting stilette, is more certainly introduced into the stricture, and the formation of a false passage thereby prevented. It consists of a graduated elastic catheter, with a niche for the reception of the caustic, which is placed on a metal shaft, haying its extremity spiral, so that it may be more flexible and more readily applicable to the curves of the urethra, and of a silver or gold stilette, which is conveyed through the sheath of the instrument, and also guides it in passing forwards into the stricture (6). 1699. Opinion is still very much divided as to the preference of the treatment of stricture by bougies, and their destruction by caustic. It must be borne in mind, however, in making the comparison, that the mischief usually assigned to the destruction of strictures by caustic, has occurred only by the use of armed bougies, (par. 1689,) but not since the improved method of Ducamp; by which it is believed that there is greater certainty in the application of the caustic, and that the cure is quicker and more constant than by dilatation ; that the pain is less as experience proves; that the hardened part which forms the stricture is very little sensitive, and that in the cauterization there is only pain when the sound part of the urethra is touched with the caustic. These cir- cumstances are the more weighty, the older and tougher the strictures are, as only in recent cases, and when the stricture is easily extensible, and especially if short, can they be soon cured with the dilator. In strictures which are very close, artd also not very long, dilatation may, indeed, be of some service, but the cure is very tedious, and not so ra- dical as by cauterization. The preference given to bougies, because long, and several strictures can be treated together, applies equally well to the improved modes of treatment with caustic. Also in great sensi- bility of the urethra, in which the presence of a bougie can well be borne, and the above-described symptoms (par. 1686) are to be dreaded, the sensibility is often much blunted by cauterization. These advantages, (a) Above cited, pi. iii iv. (b) Above cited, pi. i. f. 1, 2. 3. 84 TREATMENT OF however, even in the best modes of applying caustic, are not to be received as general and unconditional; for even with them severe inflam- matory symptoms and false passages may be produced, especially if the stricture be seated at the hind part of the urethra. The rapidity with which cauterization brings about the cure, is counterbalanced by the transient nature of its result, as the seat of the scar in the urethra, after complete subsequent dilatation, has always a decided disposition to con- tract, by which the most stubborn form of stricture is produced. I have seen in many instances, and even in patients who have been cauterized by Ducamp himself, relapses, the cure of which was exceedingly diffi- cult. Although the dilatation with the bougies is more tedious than cauterization, yet I must assign to them the greater certainty of a perma- nent Cure. But after the natural width of the urethra has been restored the introduction of bougies must be repeated from time to time; and it must be especially noticed that in a stricture, which has been many years forming, and has been of long continuance, the canal of the urethra is not in the course of a few weeks to be restored to its natural condi- tion. It is especially not attending to these circumstances, that in dila- tation, lays the foundation of relapses. Only in very old hard strictures, in which dilatation cannot be effected, or is very painful and intolerable, do I consider cauterization to be indicated. Also in fungous degeneration of the mucous membrane of the prostrate gland, which occurs in long-contined strictures (par. 1675) when, besides a copious secre- tion of mucus, a sort of fleshy lumps is discharged with the urine, and the urethral canal is not narrowed. Lallemand (a) has touched every degenerated mucous membrane with his sound in order to decide on its vitality. [Upon the employment of caustic in the treatment of strictures Astley Cooper says:—"The use of caustic has certainly been very much abused, and in many in- stances has produced the very worst consequences, and I would say that it never ought to be employed, exeept where the stricture is accompanied with fistula in perinaeo, and that fistula behind the stricture; then there can be no apprehension of the caustic occasioning retention of urine, which it has done when injudiciously em- ployed." (p. 224.) Brodie observes:—" I very rarely use the armed bougie in my own practice, and I never resort to it in the first instance. My reasons for preferring the other methods of treatment, in ordinary cases, are these:—first, although the caustic often relieves the spasm, it,also very often induces it. It is true, that in many instances it enables a patient to make water with more facility; but in many instances, also, it brings on a retention of urine ; secondly, haemorrhage is a more frequent consequence of the use of the caustic than of the common bougie, and it sometimes takes place to a very great and to an almost dangerous extent; thirdly, where there is a disposition to rigours, the application of the caustic is almost certain to produce them; and fre- quently the application of the caustic induces rigours where there had been no manifest disposition to them previously; fourthly, unless used with caution, the application of caustic may induce inflammation of the parts situated behind the stricture, terminating in the formation of abscess. I have known some cases of abscesses formed under these circumstances, which, from their peculiar situation, have proved more troublesome and more difficult to manage than the oriainal dis- ease." (pp. 61, 2.) s Upon the same point Lawrence says:—"From the various results which attend the free employment of caustic in the urethra, I think that we may safely sav it is a mode of treatment not applicable to bad cases of stricture; that is, cases where the change of structure is considerable, and the contraction is very extensive • and in cases not so serious we know that the application of caustic is not necessary for the simple bougie, sound or silver catheter, will accomplish the object we have in view The use of caustic has, in general, been very little favoured on the continent; they (a) Above cited, p. 76. STRICTURE OF THE URETHRA. 85 have generally healed strictures, there without it, and have been averse to it from knowing its ill effects; it has been partially employed in this country, but never got into very great use, and I believe has been generally less and less used, so that at present it is but seldom adopted in the treatment of stricture of the urethra." (p. 802.) With these opinions, as to the disadvantage of using caustic, I fully concur; and I rarely employ it in treating strictures. Another reason may also be given against it, which is, that though for a time, that time only, however, when the slough of the cauterized stricture has been thrown off, and the part is still sore, it may enlarge the passage of the urethra, yet as the sore surface heals a new and closer scar is formed, by which the previously narrowed passage will be necessarily rendered still smaller. Every young student knows the common mode of contracting apertures in the soft, and even in the hard palate, by producing sloughs of their margin, with the certain knowledge that the subsequently forming scar will diminish the size of the hole, and that a repetition of the same practice will at last completely obliterate it. And the result must be the same by its application to a stricture, although at first there may be a seeming improvement. I must confess I cannot understand the reason why, although objecting to the use of caustic under other circumstances, Astley. Cooper allows it when there is perinaeal fistula.—j. f. s.] 1700. Cutting into the stricture, and subsequent dilatation, has been also recommended for its more speedy removal; and for this purpose various modes of proceeding have been advised. The older surgeons used the trocar and the pointed sound {a). Doerner {b) recommended a tube through which a stilette, with a lancet point,-should be passed, Dzondi (c) a catheter open at its end, through which a lancet-shaped knife could be carried forwards and backwards ; and in like manner also McGhie (d), Amussat (e), Despiney (f), Dieffenbach {g), and Tan- chou {h). These modes can only be employed with safety in short and not very tight strictures. The proper use of bougies and caustic cer- tainly render it unnecessary, and it can only be considered as indicated when neither dilatation nor repeated cauterization have any result, when the stricture remains hard, and the urethra does not acquire its natural calibre. Jameson (i) seeks for the causes of stricture in an unnatural contraction of the transverse fibres of the m. accelerator urinae, at its fore part, which cross the urethra at right angle, as well as of the same part of the m. levator ani, in contact, with the urethra. For the radical cure of this disease, he cuts through the just-named parts, partly through the penis, and partly through the perinxum. Upon breaking through strictures with the conical catheter, refer to retention of Urine (par. 1813.) [Dickson, On Urethrotomy; in N. Y. Journ. of Med. and Surg., vol. 2. 1841.—g. w. n.] 1701. In stricture of the Urethra behind the bulb, especially if a hard, stiff bougie be used, if with it, or with a cather, force be employed, or if there be abscesses near the urethra, its walls may be easily torn, and by (a) Lafaye and Vigueri ; in Chopart, (e) Above cited, pi. ii. above cited, vol. ii. p. 328.—Allies, Traite (/) Archives generates de Medecine, vol. de8 Maladies de 1'Uretre. Paris, 1755. p. 73. xi. p. 146. 1826. May. (b) Vorschlag eines neuen Mittels, hari- (g) Hecker's allgem. litt. Annalen. p. 165, nackige HarnrOhrenverengerungen leioht 1826. The cut should be made from behind und aua dem Grunde zu heben; in von Sie- forwards. Proper instruments for the dila- bold's Chiron., vol. i. p. 259. tation are recommended. (c) Geschichte des klinishen institutes fur (h) Above cited, pl.ii.—Stafford, On Per- Chirurgie und Augenheilkunde zu Halle, foration and Incision of Permanent Stricture 1818. pi. ii. f. 1-3. of the Urethra by the Lancet Stilcttes. Lon- (d) Edinburgh Med. and Surg. Journal, don, 1836. 8vo. Third Edition. vol. xix. p. 361., 1823. (i) Medical Recorder, 1824, April, p. 251. 86 TREATMENT OF STRICTURE OF THE URETHRA. the entrance of the catheter or bougie, a false passage formed ei her in the spongy substance of the urethra or in the space between the bladder and the rectum. This is easily perceived when the instrument is pushed forwards, with much pain, and on its withdrawal, which is done readily, no urine, but only blood flows out. This false passage, in most instances, renders the introduction of a bougie or catheter difficult or impossible, because they always run into it. The careful impress with Ducamp's exploring sound, and the introduction of a straight bougie or sound, or the application of caustic with Lallemand's sound, in the proper direc- tion of the urethra, may render the introduction of the catheter possible. If this cannot be done, and infiltration of urine occur, the following must be the treatment. A sound must be passed into the urethra is deep as possible, and a cut made from without towards its point, which will certainly be found behind the stricture. If the false passage be be- tween the urethra and the body of the penis, the urethra will be laid open, the point of the sound having been first bared. A sound is to be introduced into the opened urethra, thrust towards the glans, and the stricture broken through ; or two sounds must be -introduced, one by the mouth of the urethra, and the other by the wound to the stricture, and pressed together in the proper direction, for which purpose a pointed sound is best; and thus the stricture is penetrated. An elastic catheter is then introduced from the opening of the urethra in the wound, and carried into the bladder. If the false passage be between the urethra and the external skin, the cut must be made through the latter upon the sound, the urethra opened, and an elastic catheter introduced." The treatment of the wound is to be conducted according to the rules al- ready laid down (par. 965.) [I cannot agree with the method, here recommended by Chelius, of passing the 'sound into the bottom of the false passage; for, if this be done, there will be con- siderable difficulty in finding the urethra. The instrument should be carried down only to the stricture, and then its point cut upon; which done, the stricture must be cautiously cut through, from before, backwards in the mesial line, by little and little, and the urethra behind the stricture continually sought for with a probe's point, the patient being at the same time directed to strain, so as if possible to force out urine, the point of escape of which will afford a guide to the exact track of the urethra. Much caution is requisite, that the urethra be not completely cleft, and the suspensory ligament deeply cut into, by which the difficulty in discovering the urethra is considerably increased. This is an accident to which young and not much practised operators are very liable to fall, and be sorely hampered by. The division of a stricture, and the re-connexion of the two portions of the urethra by a catheter is generally an operation of difficulty under the most favourable circum- stances, but when the neighbourhood of the canal has been ploughed up with false passages, the difficulties are considerably increased. It may be well to mention, that the first cut should be made in the raphe, and the whole operation continued in the mesial line; and I do not think any material damage is done by cutting through the bulb of the penis, which, indeed, is often absolutely necessary, although some practitioners imagine that the generative functions of the organ are thereby interfered with, to which, however, I do not assent.—j. f. s.] 1702. When the urethra is closed, as a vice of the first formation, there is either only a superficial membranous closure of its mouth, or the growing together may be deeper situated. In the former case, the pre- puce is to be drawn back over the glans, till the tip of the glans is ex- posed, and then a lancet thrusts in, with its edges upwards and down- wards, through the closing membrane, and reunion prevented by the insertion of a piece of linen smeared with oil, or of a piece of bougie. OF CLOSURE AND NARROWING OF THE VAGINA. 87 In the latter, a thin trocar must be pushed in, according to the direction of the mouth of the urethra, till it enter the canal, which must be kept open by introducing a piece of bougie ; or if this cannot be done, the urethra is to be opened where the collected urine bulges it out. I was obliged to do this in an accidental case of growing together of the ure- thral orifice, arising from a destroying venereal ulcer, in which there was not the least trace of an aperture in the hardened part to be dis- covered. When the urethra opens at some distance from the glans (Hypospadias) it will be necessary for the relief of impotence consequent thereon, to perforate the glans with a trocar up to the false orifice, to introduce a canula, and to heal up the lower opening, which must be previously scarified. It is rare that this union can be ef- fected, which, however, does not always frustrate the object of the operation, as the discharge of the semen through the new aperture will take place. According to Wal- ther (a), the closure of the lower aperture should riot be at all cared for. It has also been advised, if this operation do not succeed, to cleave the glans from the urethra up to its very tip, and to heal the wound over a tube introduced for the purpose, or to cut off obliquely a pie'ce of the glans from the false urethral orifice to its tip. The cases, however, are rare in which this degree of misformation becomes the cause of impotence. In one case, a child in whom the urethra opened at the root of the penis, Dupuvtren (b) formed by means of a thin trochar, a new canal, which he caute- rized throughout its whole length with the actual cautery ; and after the severe in- flammatory symptoms had passed by, and the slough had been thrown off, he kept it open with an elastic sound. The fistula closed. [On Hypospadias, consult a paper by Mettauer, in the American Journ. of the Med. Sci. vol. 4, N. S. 1842,-and Bushe, in N. Y. Med. Chir. Bulletin, vol. 2, 1832.—g. w. n.] XL—OF CLOSURE AND NARROWING OF THE VAGINA. 1703. Closure of the Vagina (Atresia Vagine, Lat.: Verschliessing der Mutterschiede, Germ.: Imperforation du Vagin, Fr.) may be either a vice of the first formation, or may occur subsequently by its growing together. In the former case it may depend on union of the labia and nymphe throughout their whole extent, in the midst of which commonly a white line is perceived, through the hymen, which has no aperture, and is also both firmer and tougher, or by a similar membranous closure more or less high in the vagina, or the passage of the vagina is closed by a fleshy mass. In the latter case, the closure of the vagina is the consequence of a growing together which takes place after ulceration and wounds of its walls. 1704. If in congenital closure of the vagina, the orifice of the urethra be not also closed up, it is rarely discovered before puberty. Then as menstruation comes on there is pain in the back, pressure, straining, weight in the genitals, fullness of the belly, frequent urging to void the urine, sometimes complete retention, difficulty in going to stool, and the like, and no menstrual discharge appears. These inconveniences at first appear monthly, and subside; but at last, when the collection of the blood is considerable, they no longer subside, but increase every month, (a) Salzb. Med.-Chir. Zeitung, vol. i. p. Edit, par Sanson et Begin, vol. iv. p. 435.— 188. 1813. Dieffenbach; in Hamb. Magaz. der Ausl. (b) SABATiER,MedecineOpdratoire. Nouv. Liter., vol. iv. part i. » 88 OF CLOSURE AND and general symptoms appear also, anxiety, pale countenance, pain in the belly, faintness loss of sleep, labour-like pain in the genitals.' If the collected blood can find no outlet, it gradually increases in quantity, so that it distends the womb, and empties itself by the Fallopian tubes into the cavity of the belly, or menstruation may be set up in some unusual way. Local examination always readily discovers the closure of the vagina. When this depends on the hymen, or on a mere skin, it is ah ways distended like a sac, by the collected blood, descends and fluctu- ates. 1705. The narrowing of the vagina extends either throughout its whole length, or is confined to one part. In the former case it depends on an arrested development of these parts; in the latter, is usually the consequence of injury of the vagina with loss of substance, in difficult labour, in which a part has been destroyed by gangrene, and the scar contracts the canal, or bands are formed which cross the vagina, or par- tial union of the passage takes place. There are sometimes one or several small holes in the membrane closing the vagina, or the hymen, although pervious is unusually tough. According to the degree of nar- rowing various symptoms may be produced, as obstructed menstruation, pain in connexion, and the }ike. Although the complete introduction of the penis into the narrow vagina be not possible, yet pregnancy may occur. 1706. The cure of the closure of the vagina consists in opening it to such extent that it can perform its functions, and in preventing its re- union. This operation is more or less difficult, according as its closure is at the orifice or higher up in the vagina, as it is thinner or thicker, or more or less extensive. The prevention of reunion is often attended with considerable difficulty. 1707. In complete closure of the entrance of the vagina by the hymen, the person must be laid on her back with the thighs drawn up and sepa- rated ; the labia are to be held aside by assistants, and a lancet passed into the middle of the stretched membrane, without injuring the rectum or bladder. The aperture is to be enlarged with curved scissors, or with a narrow curved bistoury, introduced upon a director. When the hymen is firm and tough, some practitioners advise the removal of the flaps thus formed. If the operation be performed on a child, or in a case where there is not any collection of blood, especial caution is requisite to avoid injuring the bladder or rectum. The membrane must then be divided with cautious cuts, and previous introduction of a sound or catheter into the urethra, to prevent its being injured. When the urethra is also covered with this membrane, the operation must be performed with the greatest care. If the labia be completely united, they must be stretched as much as possible to either side, and divided in the middle with care- ful strokes of the knife, till a director can be introduced, and upon it a button-ended bistoury must complete the necessary enlargement. The same proceeding must be adopted if the entrance of the vagina be closed by a fleshy mass (a). 1708. If the mouth of the vagina be only partially closed by the hymen, or if the labia be united, a director must be introduced through (a) Donauld; in Journal de Medecine, vol. xxxvii. NARROWING OF THE VAGINA. 89 the aperture, usually existing at the upper part near the urethra, upon which a narrow button-ended bistoury is passed, and the connexion di- vided to the necessary extent. [In infants it is better not to use a knife, but merely to pass a probe through the aperture above down to the bottom of the os externum, and then pressing the Con- necting skin with the probe point upon the finger-nail, till it make its way through, which is generally done with ease; one end of the probe must be held steady whilst the other is drawn forwards, and tears its way out. A piece of lint inserted between the parts is all that is needful. And I do not recollect a case among several on which I have operated, that required any further interference.—j. f. s.] 1709. If the closure be more or less deep in the canal of the vagina, its condition and extent must first be carefully ascertained by examina- tion by the vagina and rectum. After emptying the bladder and rectum, the oiled finger of the left hand is to be carried up to the closed part, placed upon its middle, and a narrow scalpel, guarded with plaster to within an inch of its tip, or a. pharyngotome, or Osiander's hystero- tome (a) is to be introduced and thrust in the direction of the vagina, through the closed part. The aperture is to be'enlarged, rather by pressure than by sawing with the knife, according to the situation, where it can be done without danger of wounding the bladder or the rectum. The point of the left finger is then to be introduced into the opening, which is to be enlarged with a button-ended bistoury, to the extent and in the direction where it can be done most safely, and seems most ne- cessary. In complete closure of the vagina, without any symptoms of retained menstrual fluid, the operation is contra-indicated, as the womb may be wanting, and the blind extremity of the vagina may touch the peritonaeum. Columbus (b), Bousquet (c), Mever (d), and Kleinkosck (e), have given cases of this kind. Stein (/) and Busch (g) operated on such cases, and opened the peritonaeum, in consequence of which the woman died. In a case of Qberteuffer's (h), the woman did not indeed die, but the operation was useless. In all these cases the women had not men- struated. 1710. When the canal of the vagina is only partially closed, a button- ended bistoury is to be introduced by means of the left fore-finger or a director, and the connexions divided to the proper extent, without wounding the bladder or rectum. Membranous bands are best divided with blunt-ended scissors, which are introduced upon the left fore-finger. If closure of the vagina accompany pregnancy, the operation must be first performed, when, the pains coming on the membranes present, which can be easily felt through the vagina or through the rectum {i). [My friend Dr. Locock informs me that he attended a lady who, in consequence of previous difficult labour with tearing of the perinaeum and vagina into the rectum, had as she recovered numerous bands-formed across the vagina. She became again pregnant, and great fear was entertained as to the result of the delivery. He allowed the labour to go on as usual, and as the child's head descended, and the bands (a) Neue Dendwflrdigkeiten fur Aertze und Geburtshelfer, vol. i. p. ii. f. 4. Getting. 1757. (b) De re anatomica, book xv. p. 495. (c) Journal de M6decine, vol. vi. p. 128. 1775. (d) Schmucker's vermischte chirurg. Schrift., vol. ii. p. 299. (e) Dissert, de Utero deficiente. Prag. 1777. (/) Hufeland's Journal. May, 1819. (g) Rust's Magazin, vol. x, part 2. (h) Stark's neues Archiv. vol. ii. p. 227. (i) Naegle, Erfahrungen und Abhand- lungcn aus dem Gebiete der Krankheiten des Weiblichen Geschlects. Mannheim, 1812, p. 334!—von Seibold, £., Handbuch zur Eikenntniss und Heilung der Frauen. zimmerkrankheiten. Frankf., 1821. Se- cond Edition, vol. i. p. 216. 90 OF CLOSURE AND NARROWING became stretched, he divided them carefully with a bistoury, and the case did well. A second pregnancy and delivery followed under similar circumstances. If no ope- ration be performed, and the child's head cannot descend, the womb will burst, and as in the case related by Kennedy (a), a triangular flap of the mouth and neck of that organ be thrown down into the vagina. In another case, which occurred to Labat7 one band had been divided, and whilst waiting for pains to force the other,. the whole recto-vaginal septum gave way, and the rectum and vagina became one cavity, leaving, however, the sphincter ani unhurt.—J. v. s.] 1711. If the vagina be only narrowed, it may be attempted to enlarge it gradually with bougies, sponge tent, relaxing injections, and the like. If pregnancy occur during such narrowing, the vagina often yields during that period, and during labour, to such extent, that although previously it had not the width of a quill, yet the expulsion of the child is effected (b). In cases where this yielding does not follow, some sufficiently deep cuts must be made in the narrowed parts (c) ; and, if possible, they should be made on the sides, as if they be directed from before backwards, there is danger on account of the growing together of the vagina with the bladder and the rectum, of wounding them. If the vagina be ex- tremely narrow, opening the head by a cut through the perineum may be required (d). 1712. If the menstrual blood be collected behind the closed vagina, it escapes after the opening is made, and is black and free from smell. It must be completely emptied by injection, otherwise it will putrify on the admission of air, and unpleasant symptoms will be produced. At first the most proper injections are those of luke-warm water, of decoc- tion of mallows or marshmallows ; but so soon as there is the least smell tincture of myrrh should be added, or injections of bark, with the addi- tion of acid, spirits of camphor, solution of chloride of lime, and the like. If there be active inflammation, smart antiphlogistic treatment must be employed. In order to prevent reunion, it is sufficient, after dividing the labia, to keep them separate with a piece of oiled linen. After division at the entrance of the vagina, a sufficiently thick plug of lint must be introduced. Where the narrowing was high up in the va- gina, and tough, its reunion is much to feared; in such cases it will be necessary to oppose this disposition by the introduction of thick plugs of lint, sponge tent, elastic cylinders, and the like. The use of dilators often very considerably assists this means. If it happen that, under these circumstances, symptoms of violent irritation ensue, a correspond- ing cooling and soothing treatment must be had recourse to. XII.—OF CLOSURE AND NARROWING OF THE MOUTH OF THE WOMB. 1713. The closure of the mouth of the womb is either a vice of the first formation, or first occurs at a later period, and may depend on a membrane closing the aperture, or on its growing together. The symp- toms thereby produced depend on the retention of the menstrual blood, SnJiaQo°N'S Med-Chir- Jour-> vo1 x*xi. (e) Petit, J. L-, Traite des Maladies chi- p. o/U, lBc(9. rugicales, vol. vi. p. 110 (6) Antoine ; m Hist, de l'Academie des \d) Champenois ; in Journal de Medecine, Sciences, 1712, p. 48.—Obs. Anat. 2.—Toi- vol. xli. son, ibid., 1748, p. 83.—Obs. Anat. 1. OF THE MOUTH OF THE WOMB. 91 or if the closure first occur during pregnancy, on the obstruction of the labour. 1714. In the former case the closure of the mouth of the womb may be presumed, if on the appearance of the symptoms accompanying men- struation, no blood flows; if this, again, happen regularly, the womb gradually enlarges, and the belly swells. On examination the vagina is found perfectly free, the distended mouth of the womb descends into the pelvis, and may be pushed upwards and backwards by introducing the fingers into the vagina. If the mouth of the womb be closed by mem- brane, it is often found filled out like a sac. The closure of the outer mouth of the womb may be distinguished,by the finger, and that of the inner by the careful introduction of a sound. 1715. If the blood collected in the womb cannot escape, it may, as it continues increasing, make its way through the Fallopian tubes into the belly, and cause fatal symptoms. But if the mouth of the womb be closed by membrane, the membrane may be torn by the pressure of the blood which will escape. The only remedy consists in opening the closed part. 1716. When the outer rnouth of the womb is closed, the forefinger of the left hand, with its palm or surface upwards, must be introduced up to the part to be opened, upon it a curved trocar, pharyngotome, or Osiander's hysterotome is to be passed, and the membrane closing the mouth of the womb pierced. But if the canal of the neck of the womb, or its inner mouth, be closed, then must the pharyngotome or hystero- tome, introduced in the way described, be carefully thrust through the part to be opened, and when the cavity of the wound is penetrated the opening must be enlarged sufficiently with the bistoury. 1717. The discharge of the menstrual fluid must be favoured by in- jections, as was done in opening the vagina, and its reunion prevented by a sufficiently long plug /oi lint inserted into the new opening, or by the introduction of an elastic tube. The after-treatment must be guided according to appearance of inflammatory and spasmodic symptoms. The inflammatory symptoms after this operation are so severe that Dupuytren decides upon entirely giving it up, and rather to allow the patient to die more quietly and slowly than to speedily hasten her death by the operation, which always results from inflammation of the womb, and which is the more violent in proportion to the distension of the womb. (Pigne.) Successful cases following this operation have, however, refuted Dupuytren's assertion. Du Cumin (a) employed Dupuytren's double lithotome in a case of secondary union of the mouth of the womb, and the result was permanent. The greatest care must be exerted for the complete discharge of all the decomposed blood. 1718. When the mouth of the womb has grown together during preg- nancy, or is so changed by hardening and schirrhous degeneration, that it will not dilate during labour, perhaps the whole lower part of the womb may descend so low, that there may be dread of it tearing, then the opening or enlargement of the mouth of the womb must be resolved on {Hysterotornia vaginalis, Lat.; Scheiden-Kaiserscenitt, Germ.) 1719. In schirrhous degeneration, or hardening of the mouth of the womb, a button-ended concave bistoury must be introduced into it upon the forefinger of the left hand, a cut made into it, and continued from (a) Gaz. Med. de Paris, vol. viii. p. 91. 1840. 92 OF CLOSURE AND NARROWING OF MOUTH OF THE WOMB. two-and a half to three inches into the substance of the womb. The direction of the cut should be to the left, or right, or forwards, or back- wards, or in any other way, for the purpose of giving the wound proper size, according to the position of the womb, and, as far as possible, to cut into the part least changed. A cut has also been made in stricture of the mouth of the womb, during labour, throughout its whole length (a). The labour proceeds maturally* or may require to be finished by manual and instrumental assistance. 1720. If the mouth of the womb be completely closed, or cannot be felt, a blunt-ended scalpel is to be introduced on the forefinger of the left hand, and division of the protruded mouth of the womb made care- fully from before backwards, or from one to the other side. When its cavity is reached, the cut must be made by the button-ended bistoury in the direction laid down, and if the cut cannot be made of sufficient size a second must be made to cross the former. The farther treatment is the same as in the former cases. See also upon this subject— Lauverjat, Nouvelle Methode de pratiquer POperation Cesarienne. Paris, 1788. Berger, F. G., Ad. theoriam de fcetus generatione Analecta. Praemissa est rarioris embryulcise casus brevis historia. Leipsiae, 1818. Rayner, F. B.; in Salzb. Medic-chirurg. Zeitung, 1821, p. 398. Wheelwright; in Medical Recorder, 1821, p. 361, April. Cafe; in the Journal hebdomadaire. 1824, May. (a) Moscati; in Omodf.i, Annali Uni- in Med. Jahrbuchern des^isterl. Staates,vol. versali, vol. xi. p. 257. IS!9.—Wagner; xxii. p. 367. [ 93 ] FOURTH DIVISION. DISEASES DEPENDING ON THE PRESENCE OF FOREIGN BODIES. 1721. Under the term foreign bodies are included not merely me- chanical bodies conveyedy>om without into our organism, but also those products which, generated and retained in our organism, react upon it injuriously. 1722. They may, therefore, be treated of according to the following division:— I. Foreign Bodies brought into our organism from without, 1. Into the nostrils. 2. -------mouth. 3. -------oesophagus and intestinal canal. 4. -------air tube. II. Unnatural collections of natural products. a. In their natural cavities and receptacles (retentions.) 1. Ranula. 2. Retention of urine. 3.------------the foetus in the womb or in the belly (Cesarean operation, division of the pubes, Gastrotomy.) b. External to their proper cavities and receptacles(extravasations.) 1. Blood-swellings in newly-born children. 2. Hematocele. 3. Extravasation of blood in joints. III. Collections of diseased products. 1. Lymph swellings. 2. Dropsy of the mucous bags. 3.---------joints. 4.---------the chest and empyema. 5. ---------the head and spina bifida. 6. Collections of pus in the breast-bone. 7. Dropsy of the pericardium. 8.-------------belly. 9. -------------ovaries. 10. Hydrocele. IV. Formations of stony concretions. Here are reviewed all those diseased conditions which have been already con- sidered, on account of the close relation in which they stand to others; for instance foreign bodies penetrating from without, and the extravasations in the various cavi- ties, the retention of the bile, of the spittle^in the Stenonian duct, and the like Vol. iii.—9 94 FOREIGN BODIES IN THE NOSTRILS, MOUTH, First Section.—OF FOREIGN BODIES INTRODUCED INTO THE BODY FROM WITHOUT. 1723. What relates to foreign bodies, which in various ways compli- cate wounds, has been already treated of, (par. 306 and 338,) both as regards their effect, and the necessity, and the kind and mode of their removal. Here only will be considered those which penetrate into the open cavities of our bodies. I._OF FOREIGN BODIES IN THE NOSTRILS. 1724. Foreign bodies which get into the nostrils, are retained either by the swelling which they undergo, as beans, peas, and the like, which children frequently'thrust into their nose ; Or, if they do not themselves enlarge, are enclosed by the swelling of the mucous membrane of the nostrils, which they set up. 1725. The removal of these foreign bodies is not very difficult if there be not much accompanying swelling ; it is often, however, rendered easier by the softness which most of them acquire as they swell up. For their removal, curved, dressing or polypus forceps are used; and if they cannot be got out whole, we endeavour to break them to pieces. When, in gun-shot wounds of the face, balls remain lodged in the nostrils, they in general so quickly produce violent swelling and inflammation that it is impossi- ble to get them out. In many cases they may remain till discharged by "suppuration. But if, by their presence, violent symptoms are produced, they must be removed; and if, on account of the peculiar form and size of the foreign body,Jhe opening' of the nostrils offer much obstacle, it maybe necessary to slit up one or other of them, and after the removal of the foreign body, to reunite them by the application of a v stitch. The position and size of foreign bodies is often such that they cannot be seized with the forceps; in these cases Dupuytren (a) advises that they should be pushed backwards, so as to drop into the mouth, which is the way they generally take if left alone for a time to escape of their own accord. [Astley Cooper used to mention an instance pf a ball having been received in the frontal sinuses, which for a time remained quiet, but at last its weight caused ulceration; it descended through the nostrils, and passing through the floor of the nose into the mouth, caused severe bleeding from the palatine artery—j. f. s.] II.—OF FOREIGN BODIES IN THE MOUTH. 1726. Foreign bodies which remain sticking in the inside of the. cheeks, in the tongue, or in the palate, may cause severe pain, diffi- culty in swallowing, and very considerable swelling of the tongue. They can be easily discovered by careful examination, and removed with the forceps. If allowed to remain, they are generally soon got rid of by suppuration. [I have very recently operated on a case in which a piece of tobacco-pipe, an inch and a half long, had been lodged in the cheek for'ten months, without the pa- tient being ayv are of it. He had fallen with his pipe in hand, and wounded the outside of his cheek; much swelling ensued, and after a few weeks the wound (a) Blessures par Armes de guerres ; publ. par. Maux ct Paillard, vol. ii. p. 232. AND OESOPHAGUS. 95 healed, but he could not open his mouth completely nor without pain. Twice during the following twelvemonth the swelling, which still remained, became very painful, increased, and suppurated. The last time he came to me, and the piece of pipe was readily discovered, running from half an inch behind the angle of the mouth horizontally back towards the angle of the jaw, the mouth could not be opened more than half an inch, and each time the jaw was depressed he had great pain at the angle of the jaw. I cut upon the scar, which was very apparent, but had some little difficulty in detaching the end of the pipe, as the scar had probably sunk into its hollow; this done, however, it was easily drawn out with dressing forceps, like a dirk from its scabbard, and was evidently smeared with a mucoid secretion from the sides of the cavity, which it had made for itself. In a few days the effects of the operation ceased ; he opened his mouth freely, and without pain, and the sinus filled up. Bodies may sometimes be thrust into the mouth, within the arches of the teeth, and when there become so fixed by the elevating muscles of the lower jaw, as to be incapable of removal without assistance ; I knew a case of this kind in which a girl thus fixed an apple in her mouth, which was only removed by the medical atten- dant cutting it to pieces.—j. f. s.j III.—OF FOREIGN BODIES IN THE OESOPHAGUS. Hevin, Precis d'Observations sur les corps etrangers arretes dans l'GSsophage, et dans la Trachee-artere, avec des remarques sur les moyens qu'on a employes ou que l'on peut employer pour les enfoncer ou pour les retirer; in Mem. de l'Acad. de Chirurg., vol. i. p. 44 1. -Bordenave et Destremeau, De corporibus extrancis intra ffisophagum haeren- tibus. Paris, 1763. 4to. Venel, A., Nouveau secours pour les corps arretes dans l'03sophage, ou descrip- tion de quatre instrumens plus propres qu'aucum des anciens moyens, a. retirer ees corps par la bouche. Lausanne, 1769. Monro, Alex., Jun., M. D., The Morbid Anatomy of the Human Gullet, Sto- mach, and Intestines. Edinburgh, 1811. 8vo. Guattani, Essayes sur l'GSsophagotomie; in Mem. de l'Acad. de Chir., vol. iii. p. 351. Eckholdt, J. G., Ueber das Ausziehen fremder Korper aus dem Speisekanale und der Luftrohre. Kiel und Leipzig, 1799. Large 4to; with plates. Nauta, Dissert, de corporibus peregrinis ex CEsophago removendis. Workum, 1803. Vigxardonne, J., Quelques propositions sur l'CEsophagotomie. Paris, 1805. Vacca Berlinghieri, Delia Esofagotomia e di un nouvo methodo di eseguirla. Pisa, 1820; with a plate. [Bond, H., Observations on the removal of Foreign Bodies lodged in the (Esophagus; in North American Med. and Surg. Journ., October, 1828.—g. w. k.] 1727. Bodies may remain sticking in the oesophagus on account of their size or hardness, or their irregular pointed surface. Bodies are often retained in the oesophagus, which as regards their size and cha- racter, might without difficulty have passed through it, in which case it would seem that their fixture must be ascribed rather to a spasmodic contraction of that tube. The stoppage is commonly at the upper or lower part, and rarely in the middle of the oesopliagus. [I recollect several years since examining the body of a man who was brought to the hospital, and supposed to have died of apoplexy. On accidentally removing the tongue, pharynx, and neighbouring parts, an enormous lump of beef was found com- pletely filling up the whole pharynx, and compressing the epiglottis. Inquiring about the circumstances of his death it was ascertained that, whilst eating soup for his supper, he suddenly rose from the table, went out of doors, and shortly after was 96 FOREIGN BODIES found dead near the threshold. The preparation is in the Museum at St. Thomas's. . , , , , I have known an instance occurring twice in the same person, who, had he not been a medical man, would probably have been suffocated before assistance could have been obtained. In eating his breakfast quickly, he suddenly felt choked, could not swallow the morsel in his throat, and could not breathe; he thrust his fingers back to try and pull out the morsel, in which he succeeded, and found the small portion of meat swallowed was attached by a thread of cellular tissue to another portion, which had become entangled in his teeth, and the thread had pressed down the epiglottis, so that every effort to swallow made him still worse. The same accident occurred to him a second time, but was in the same way re- lieved.—j. f. s.] 1728. The symptoms produced under this condition are, local pain, spasmodic contraction of the oesophagus, disposition to vomit, choking, or less difficulty in swallowing, symptoms of suffocation, and frequently actual suffocation, which depend partly on compression of the windpipe, partly on the spasmodic contraction of the glottis. Sometimes, and, if the body be small and painful, there is merely a local painful sensation. The inflammation may also be so violent, that it may run on to gangrene, though this in general only occurs when forcible efforts are made for the removal of the foreign body. 1729. It is often very difficult to decide upon the presence of a fo- reign body in the cesopJiagus. When a body more or less bulky, or with an irregular surface, is swallowed, if the patient feel pain at a particular spot, if swallowing be difficult and painful, and the respiration inter- fered with, yet these symptoms may be merely the consequence of the descent of the foreign body, of wound of the wall of the oesophagus at a particular spot, and of the inflammation resulting therefrom. If a bulky body remain sticking in the upper part of the oesophagus, it may often be felt externally ; or, if the tongue be strongly depressed, it's presence may be ascertained either by seeing it, by feeling it with the finger, or with a whalebone or elastic sound, or with Dupuytren's (a) oesophageal sound of elastic silver, with a little spherical ball at its extremity. These examinations must be always made with exceeding carefulness, and especially may be only made when active inflammation has not yet set in. [It not linfrequently happens that, after a person has had a fish-bone stick in his oesophagus, though he can take food, yet a soreness remains, which is generally sup- posed to arise merely from the scratching of the lining membrane, and will subside in a few days, it being presumed that, as he swallows solid food, there cannot be any thing lodging; and this more especially if an oesophageal bougie have been passed into the stomach. That this opinion may be too hastily formed, is proved by the following example. A friend of mine, whilst eating fish, suddenly felt that he had swallowed a fish-bone, and became so uncomfortable that he was obliged to leave the table, and within a couple of hoars went to his medical attendant, who pulled out a piece of fish-bone with forceps. On the following day he still continued very uneasy, his throat being very sore, and felt assured that he had still a piece of bone in his throat; his medical friend, however, very naturally considered the sen- sation depended merely on the scratch of the bone he had removed. For four days the symptoms of obstruction continued, and he was much harassed, anxious, and became very ill. On the fifth day his son, a very able surgeon, passed an oeso- phageal bougie without the least hindrance, and it was then thought quite impossi- ble there could beany thing in the passage,and that the symptoms merely depended on the previous irritation. On the evening of the very same day he suffered much pricking in his throat, was attacked with a violent cough, and threw out another (a) Sabatier, Medecine Operatoire, vol. iv. p. 52. IN THE OESOPHAGUS. 97 bone, immediately after which he became easy, and all the symptoms quickly ceased. It is presumed that this second bone had lain obliquely across the oeso- phagus, and that, as the bougie descended, one end of it had been disengaged, as the instrument distended the canal, and being thus more conveniently and loosely seated, the bone had been shot out by the cough. The remembrance of this inter- esting case will induce caution in giving a positive opinion of a foreign body not being present in the oesophagus, although swallowing may be effected, and even a bougie passed without obstruction.—j. f. s.] In the College Museum there is the whalebone handle of a punch-ladle, marked "It had been in the oesophagus sixty-eight hours without doing mischief;" but no- thing more is known about it. It was in Heaviside's collection. Monro indeed mentions the case of a boy who had attempted to swallow a half- penny,; it remained in his oesophagus " three years, and possibly it might have remained there for a much longer period had he not been seized with consumption, which proved fatal to him. Upon examination the gullet was found closely em- bracing the halfpenny, and considerably expanded by it. A halfpenny stuck in the gullet of another boy for six months, and was afterwards extracted by Monro's father with a blunt-hook." (p. 18.) He also mentions an instance in which an ex- traneous body, detained at the origin of the gullet, became lodged in a sac of some length which descended behind the oesophagus, (ib.) 1730. Foreign bodies in the oesophagus may either be drawn upwards, or thrust down into the stomach, or removed by a cut into the oeso- phagus. 1731. The removal of the body upwards may be effected by vomiting, produced either by irritating the throat, or by the exhibition of an emetic, if swallowingbe not entirely prevented, or by the injection of a solution of tart3rized antimony into a vein (a). It must, however, be observed, in reference to the vomiting, that if the body firmly close the oesophageal tube, and will not be moved by the sickness, the mischief is increased, and even tearing of the oesophagus may ensue. If the foreign body be at the upper part of the oesophagus, it may often, if the tongue be strongly depressed, be seized with the finger, or with a pair of oesophageal forceps, and withdrawn. If it be lower down, it may be removed also by the forceps, or a blunt hook, formed of a piece of wire bent together: or by a whalebone sound with a piece of sponge attached to its extremity, which is to be passed below the body, and when the sponge has swollen by the absorption of the moisture, may be withdrawn. Little pointed bodies, as needles, fish-bones, and pieces of bone, are generally more easily removed with the sponge. A flexible sound, having its extremity armed with several loops of metal, has been recommended for this purpose. Bulky bodies, which completely fill the oesophagus, are very difficult of removal, because the instrument cannot be passed beyond them. Attempts at removal must always be made with great care and consideration. Delpech {b) objects to the use of the hooks and metallic loops as inefficient and dangerous. The peculiar operation of the vomiting is not merely the commotion but the in- verted contraction of the muscular fibres of the oesophagus. For the purpose of making the oesophagus slippery, mucilaginous and oily remedies, melted butter, oil with camomile tea, or yolk of egg and the like must be administered. Tobacco clysters are often advantageous in producing vomiting and diminishing the spasm. The removal of a fish-hook, which had been swallowed, the line of which remained hanging out of the mouth, by means of a perforated bullet through which the thread (a) Kohler ; in Schmocker's vermischten Hufeland's Journal, 1811, vol. vi. p. 116.__ Schriften, vol. i. p. 335.—Balk; in Mur- Graefe. senna's Journal,.vol. ii. p. 64.—Kraoss ; in (b) Precis Eleraentaire, vol. ii. p. 59- 9* 98 TREATMENT OF FOREIGN was passed, and the bullet allowed to drop down into the curve of the hook so as to shield its point, is mentioned by Bright (a). 1732. In thrusting down foreign bodies into the stomach, a whalebone sound, with a piece of sponge at one end, commonly called a probang, first smeared with oil, is employed. This mode is to be practised especially if the foreign body be soft and have a smooth surface ; but if it be rough or pointed, considerable injury to the oesophagus may be effected by thrusting it down, and it may be even of such character, that on account of its mere presence in the oesophagus, dangerous symptoms may be dreaded. Under these circumstances, only the most urgent symptoms, and the impossibility of getting rid of the body in any other way, will determine that it should be thrust down. The patient may be allowed to swallow mouthfuls of chewed bread, and the like, which often drive the body down, and a blow between the shoulders will often loosen it. If a body capable of being broken up, as for instance, a potato remain sticking in the upper part of the oesophagus and cannot be thrust down into the stomach, attempts must be made to press it upwards, with the fingers upon the surface of the throat, as Dupuytren did very successfully, and quickly relieved the patient after all other efforts had been in vain. (Pigne). Before1 proceeding to thrust an extraneous body down the oesophagus, a careful examination should be made with the finger, to ascertain if it be within reach, and can be removed ; the importance of doing this is proved by the following case, which Astley Cooper was accustomed to relate (b). A child, whilst dining with his parents on his birthday, swallowed a fish-bone, and was attacked with violent cough; Cooper not being in the way, another surgeon was found, who passed a probang; the symptoms, however, became worse, were followed by convulsions, ajid, between ten and eleven o'clock of the same evening, the child died. Having obtained permission, Cooper opened the larynx with a lancet, and found a piece of fish-bone situated just at the glottis, which he readily hooked out with his finger- nail. Dr. Brown (c) mentions the case of a woman who, in eating oatmeal porridge, swallowed a piece of a broken delf plate, whieh pierced the oesophagus on the right side, midway between the eriooid cartilage and the breast-bone. She soon made an effort to vomit, and a discharge of blood from the mouth ensued and repeated on the passage of a probang, which she thought displaced the bit of delf. On the day following she was seen by Brown, and had then inflammation and swelling of the external fauces in the line of the oesophagus, with total inability to swallow. The foreign body could not be felt externally; and a probang was twice passed with facility. Leeches and cold lotion were applied, and on the sixth day the inflamma- tion hadalmost ceased, and she swallowed well. On the ninth day she was attacked with pain in the stomach, which lasted two days, and on the tenth she vomited a pint of dark foetid blood, which continued in smaller quantities. On the twelfth day she spat up more than a pint of brown foetid sputa, and died at midnight. No examination was permitted. Brown considers that the bit of plate was at first thrust down into the stomach, and that the inflammation of the oesophagus depended on the violence with which this was done. He imagines that the fatal symptoms resulted from the hard substance wounding the stomach, especially as that ortran was com- paratively empty from the accident to her death. And that the pain in the left hyphochondrium pointed out injury to the left extremity of the stomach, near the cardia, where some krge branch of the coronary, or left gastroepiploic artery must have been divided, as the quantity of blood: poured out was so large as to colour the faecal discharges. [My friend^and pupil Tunaley, of Camden Town, has given me the following ease, which-shows the propriety of Astley Cooper's advice, and which, but forthe tJ?^^/^11 MediCaJ Record<^ 1823« (0 Edinburgh Med. and Sur* Journal, (i) MS. Lectu-cs. BODIES IN THE OESOPHAGUS. , 99 prompt and judicious treatment, would also probably have terminated fatally, although the foreign body was merely a piece of bristle from a brush, about an inch in length. A lady, whi,lst eating bread and butter, felt something in her mouth which seemed like a piece of wood, and not choosing to spit it out, as she was in a party, determined to swallow it with the morsel in her mouth. In doing this, the sharp substance lodged in her throat, produced a constant pricking, and in the course of a few hours cough and repeated attempts at deglutition. She was seen shortly after by a medical man, who examined the throat, and, finding nothing, considered it merely a case of local irritation, and treated it accordingly. Next day she was worse, and an emetic was given, which quickly aggravated the symptoms to such an extent, as to threaten immediate suffocation. Twenty-four hours after the accident, Tunaley saw her, and it was then necessary at once to perform tracheotomy, which he did immediately below the cricoid cartilage; and, scooping out its under edge, he introduced an elastic catheter, which relieved her directly. Four hours after, when the spasm had subsided, he made an examination, with his finger, by the mouth, and could just feel, when an attempt to swallow was made, the point of what he took for a pin; but it was not under command of the finger. He then passed a pair of dressing forceps, bent; for the purpose, into the throat, and, after persevering efforts, as the patient's exhaustion would, admit, during two hours, at last succeeded in pulling out a bristle, which, he considers, had penetrated the mucous membrane at the root of the epiglottis, and, by its continued irritation, had produced the spasm of the glottis.- The patient speedily recovered.—j. f. s.] 1733. When the body has caused severe inflammation and diseased contraction of the oesophagus, all attempts at its removal must be given up, and the treatment confined simply to.-blood-letting, leeching, oily in- jections, and if there be accompanying spasm, opium. When by these means the inflammation, swelling and contraction of the oesophagus have diminished, it not unfrequently happens that the body gets loose, and can be removed one way or another. 1734. Whether the body he drawn up or thrust down, frequently local inconveniences remain in the oesophagus, as wounds, inflammation, and suppuration, which require corresponding antiphlogistic and soothing treatment. Narrowing of the oesophagus may result at a subsequent period, and if the body be bulky, suppuration even may ensue. 1735. Thin and pointed bodies, needles for example, may penetrate the walls of the oesophagus and gradually make their way through the neighbouring parts, so that they often reappear at very distant parts. This more frequently occurs when the bodies have passed into the stomach, and then travel through the different organs, sometimes accom- panied with no pain, but at other times with great pain. 1736. When the foreign body can neither be pulled up nor thrust down into the stomach, if it produce urgent symptoms, and be not very low in the oesophagus, or. if it be of such kind that its descent into the stomach would be productive of great danger, then it must be removed by cutting into the oesophagus {(Esophogotomia.)^ This operation is always one of the most difficult and dangerous, though under the circumstances it must be held to be the Only means of relief, and by observing certain rules, is much facilitated. The parts of which injury is to be feared are the carotid artery, the internal jugular vein, the recurrent nerve, and the thyroideal arteries. Callisen (a), as well as Benjamin Bell and Richerand, only allow cesopha- gotomy when the foreign body can be felt externally, and in the Contrary case will have an opening made in the windpipe to prevent the danger of suffocation. According to Zang (6), however, the operation may be undertaken, if nothing be (d) Systerna Chirurgias, vol. ii. p. 421. (6) Operationen, vol. iii. p. 40. 100 FOREIGN BODIES felt externally, if only the place be known where the body is situated. In these cases also the mode of operation laid down by Vacca Berlinghieri may be safely performed. . ... [As the more serious symptoms which occur when a foreign body sticks in the pharynx or oesophagus, depend on the pressure it makes upon that part of the air- tube to which it is opposite, I think it would be advisable to perform tracheotomy in preference to the difficult and dangerous operation of cutting into the oesophagus. This mode of treatment has been successful, as in the case of the boy who attempted to swallow nine pistoles wrapped in a piece of cloth, mentioned by Habicot (a). The packet stuck in the narrow part of the pharynx, and he was almost suffocated. Attempts to thrust it down were made ; but in vain. Habicot, therefore, to relieve the most urgent symptoms, cut into the windpipe; the difficulty of breathing, the swelling and blueness of the face ceased immediately; and the money then thrust down with a leaden sound in the stomach, was passed by stool a few days after.]' 1737. According to Verduc-Guattani, the operation is to be per- formed in the following manner^ The patient having been placed in an arm-chair, or laid upon a table, and his head properly held by an assis- tant, a cut from two and a half to three inches in length must be made vertically through the skin and cellular tissue, upon the left side of the air- tube between the larynx and the collar-bone. Then, the assistant having drawn the edges of the wound asunder with blunt hooks, and the blood being absorbed with a moist sponge, it must be endeavoured to dig under the edge of the thyroid gland with the handle of the scalpel, and keeping still, on the one side of the air-tube, and using the blade of the knife as little as possible, the oesophagus is to be laid bare, and so cut into that the foreign body may be removed with a pair of straight forceps, without tearing the edges of the wound. If the foreign body be a little distant from the opening, a pair of curved forceps must be used for its removal. Any spirting vessels must be immediately taken up during the operation, as well also the thyroideal arteries, if they come in the way, before cutting them through. Eckoldt's method, in which a cut is made through the skin, close to the middle of the m. stemo-mastoideus, and the division of the cellular tissue in the triangular space formed by the division of this muscle before its insertion into the breast and collar-bone, and the oesophagus laid bare and. cut into, is manifestly less safe than that just described. 1738. In those cases in which the foreign body forms no perceptible swelling externally, and for the purpose of especially projecting the wall of the oesophagus, it has been recommended to introduce a silver catheter, or a forked curved sound, through the mouth into the oesophagus, and to raise its left wall into the wound. The arrow-sound has also been advised for this purpose. Richerand (b) objects to the introduction of any in- strument into the oesophagus, as a guide. Vacca Berlinghieri (c) has, however, proposed an instrument by which cesophagotomy is more easy and effectual than by any other mode. 1739. The patient is placed on a low stool; the head held firmly against the chest of one assistant, and the rest of the body by another. The skin-cut is to be made on the left side of the neck, in the direction of the thyroid and cricoid cartilage, on a fold of skin from the upper edge of the thyroid cartilage to two inches below it; if the m. platysma oAa) ?J?'-de,o Acad> de Chin' vol> xiL P' J^nal von Graefe und von Wal- rM Soo-rLhiTrh- ■' , • , .» T,HER' VoL V> E' 712--Chirurg. KupfertaC. (6) JNosographie Chirurgicale,. vol. iii. p. pi. cxxxv. & r 260. r IN THE CESOPHAGUS. 101 mybides be not then cut through, it must be divided with a second stroke of the knife into the underlying cellular tissue. The ectropcesophag, with the spring thrust fully forwards and thus completely closed, is to be in- troduced so deeply into the oesophagus, and so directed that its lower end corresponds to the lower angle of the wound. The fore and middle fingers are now to be introduced into the side rings of the canula, and the thumb into that of the shaft, which being drawn back, its spring end is set free, and with its olive-shaped knob, the wall of the oesophagus is thrust into the wound. The instrument is now held steadily by an assis- tant, the cellular tissue carefully cut into, and the oesophagus laid bare by drawing the m. sterno-mastoideus backwards, the m. sterno-hyoideus and sterno-thyroideus forwards, (with the assistance of the finger or a blunt hook,) and then the m. omo hyoideus, which crosses the wound obliquely, is divided on a director. The oesophagus now appears to more than the extent of an inch, and must be cut into on the side, and a little forwards, between the canula and the diverging arms of the shaft, for two lines above the olive-shaped knob of the latter, and the cut enlarged upwards as far as may seem necessary. A blunt hook is then introduced into the oesophagus, to keep it steady. The ectropcesophag is now taken out, and the foreign body moved with the finger or forceps. The ectropcesophag may be so easily arranged, that it may be used even if the operation be performed on the right side. 1740. According to Begin .{a), it is impossible to operate upon the oesophagus in the region prescribed by Verduc-Guattani's plan, or pro- perly to introduce the instruments recommended for introduction by others, and to retain them in suitable position, as the irritated parts can- not bear constant touching, and the breathing has already become difficult. His method, which is founded on the most careful considera- tion of the anatomy of the parts concerned, and which has been several times performed on living persons, is the following:—The patient is laid upon a narrow bed, his shoulders and chest slightly raised, the head a little bent back, and supported with a pillow, and the neck moderately stretched. The operator standing on the left side, makes a cut through the skin, along the groove between the sterno-mastoid muscle and the windwipe, which he begins a finger's breadth above the sterno-clavicular articulation, and carries up as high as the upper edge of the thyroid car- tilage. He now divides with long strokes the m. platysma-myoides and cellular tissue, and descends deeply into the cellular space between the windpipe and oesophagus within, and the deep vessels and nerves without, which are covered by the sterno-mastoid muscle, and the assistant, stand- ing on the patient's right side, draws inwards the parts on the inside of the wound with his fingers or with a blunt hook, and the operator, with the fingers of his left hand thrust in more deeply draws outwards the parts on the outside of the wound, and with the point of his finger covers the vessels and nerves. The m. omo-hyoideus is then seen running obliquely outwards and downwards in the upper half of the wound, which, a director having been introduced beneath, must be divided. The oesophagus now appears, and is known by its position behind the windpipe and larynx, its round fleshy surface, its movements and hardness in the attempts to (a) Diet, de M6d. et de Chirurg. pratique, vol. xii. p. 152; and Nouv. Elem. de Chirur- gie et de Med. Operat., vol. i. p. 260. Second Edition. 102 FOREIGN BODIES swallow. If the foreign body form a projection, it must be immediately cut upon; but under contrary circumstances, the knife is to be carried boldly in the middle of the wound parallel to the axis of the oesophagus, into it, and an opening made about half an inch long, from which imme- diately some mucus and spittle flow out, and in which, by the contraction of the circular fibres, the mucous membrane becomes visible. A button- ended bistoury is now introduced upon the forefinger, and the wound enlarged sufficiently upwards and downwards to admit the introduction of the forceps. It is better to, enlarge the wound upwards rather than downwards, as wounding the superior is less dangerous than wounding the inferior thyroideal artery. Every bleeding vessel must be immediately taken up during the operation. 1741. No precise rules are laid down for the removal of the foreign body; it must depend on the delicacy of the touch, manual dexterity, and thought of the operator upon the moment, to determine how the difficulties' may be best overcome. Curved and pretty strong polypus- forceps, with double curves, are in general most convenient, and a sufficient number of them, of various form and size, must be in readiness. (Begin.) 1742. After the removal of the foreign body, quick union should be aimed at according to the usual mode, with dressings; the edges of the wound are to be brought close together with sticking plaster, and the head kept inclined a little backwards and to the right side. For the first eight days the patient must be supported only with nourishing clysters and baths; and then with gelatinous substances in small quantities by the mouth; at first the patient's tormenting thirst must be quenched with Seville orange strewed with sugar, (par. 473,) and taken into the mouth. But, according to Begin, should the wound unite neither by sticking plaster, and still less by suture, as in the condition of the walls of the oesophagus, from the more or less severe inflammation and so on, agglutination, as in ordinary wounds, is not to be expected, but the edges should only be brought together, covered with perforated cloths spread with cerate, and wadding with compresses, fastened with a cir- cular bandage. As the patient subjected to oesophagotomy becomes wasted by his incapability to swallow, want of rest and so on, some nourishing broth should be conveyed into his stomach by means of an oesophageal tube, the day after the operation. IV.—OF FOREIGN "BODIES IN THE STOMACH AND INTESTINAL CANAL. Hevin, above cited, p. 520. 1743. When bodies, insoluble by the powers of the digestive organs, are thrust down or swallowed into the stomach, they may produce differ- ent symptoms, depending principally on their form and nature. Bulky bodies often pass without any difficulty through the whole intestinal canal; pointed bodies are easily retained, and produce frequently in- flammation and ulceration. IN THE STOMACH AND INTESTINAL CANAL. 103 [Of the foreign substances received into the stomach, the most remarkable account is that given by Dr. Marcet (a), of the sailor who swallowed a number of clasp knives. In June, 1799, after having witnessed a display of jugglers' knife- swallowing, he, in a drunken fit, boasted he could do the same, and accordingly swallowed four pocket-knives successively. On the following afternoon he passed one knife by stool, and on the following day two more, but the fourth knife never came away, nor gave him inconvenience. In March, 1805, in the course of a couple of days,he swallowed fourteen knives more; but on the following morning was attacked with constant vomiting and pain at his stomach, which compelled him to go to the hospital, and in the course of a month, "he was safely delivered of his cargo." In December of the same year, he swallowed on one day five, and on the next fourteen more. He was very ill the next day, and obliged to. put himself under medical care, but without benefit till three months after, when having taken castor oil, he felt the knives "dropping down the bowels," and became easier, but was not aware of having passed any. In June, 1806, he vomited a knife-handle; in November he passed some fragments, and again in February, 1807. In August of the same year he was admitted into Guy's Hospital., where at first his account was not believed, but he held fast to his story, and as he suffered intense pain at the region of the stomach, and a hardness was thought to be felt, some credence was at last given, and his stools being noticed were found of a deep black, indicating an accumulation of ferruginous matter in his bowels. On examining the rectum, a por- tion of the knife was felt lying across it, but could not be extracted on account of the great pain he suffered in the attempts to grasp it. Various attempts were made to dissolve the knives, but without success, and at last, in March, 1809, he died in a state of great emaciation. On examination, one of the blades and one of the back springs were found in the intestines, the latter, four inches and a half long, had transfixed the colon opposite the left kidney, and projeeted into the cavity of the abdomen, while the other was stretching across the rectum, with one of its extremities actually fixed in the muscularparietes of the pelvis. No stool had, however, escaped, nor were there any signs of active inflammation. In the stomach were thirty or forty fragments, of which thirteen or fourteen were evidently blades, much corroded and diminished in size. They are all in the Museum at Guy's Hospital. Another instance is also related by Dr. Barnes, of Carlisle (b), of a juggler, who, on 17th November, 1823, accidentally swallowed a table-knife with a bone handle, together nine inches in length. The account given by the man was, that "having offered for a small sum of money to swallow a table-knife, a new one was accord- ingly brought from a neighbouring shop. The method by which I pretended to swallow it was, to'pass the handle and part of the blade down my throat, and hold the point of the knife fast with my teeth. When I was on the point of drawing it out again, some person, coming unexpectedly behind me, gave me a smart stroke on the back, the surprise of which caused me to lose hold of the point, and imm'e4 diately the whole knife slipped into the. stomach. I directly made very violent efforts to throw it up, but in vain, and the endeavours of the surgeon were equally useless." The man immediately became very much alarmed, expecting instant death. Attempts were made with the fingers and with long forceps to seize the knife, but it was far beyond their reach, and could not be felt on the external surface of the stomach. Next day he complained of pain in his stomach, for which he, was bled, and a clyster given; and afterwards, having pain in the left shoulder shooting across the chest to thfe stomach, he was bled again. Soon after the handle of the knife could be felt very distinctly by pressing gently on the navel, though slight pressure gave him considerable pain; but a single cup of tea or a little food of any kind distended the stomach so much that it entirely disappeared. Various sugges- tions were made, and among others gastrotomy, but the patient would not consent to it. He was able to walk about a little during the day, and could sleep at night on his back, but not on either side. He was frequently squeamish and sick at stomach, and sometimes felt a severe twisting pain in that organ. He kept quiet till 28th December, when he left on his way to London, but died at Middlewich on the 16th January following. From the account it is very evident that he never laboured (a) Med. Chir. Trans., vol. xii. p. 52, 18Q2. (b) Jameson's Edinburgh Philosoph. Journ., vol. xi. p. 319,1824.—Hadfield, A State- ment of the Case of VV. Dempster, a juggler, who died in consequence of having swallowed a Table kife. Middlewich. A pamphkt. 104 FOREIGN SUBSTANCES under any urgent symptoms, and seems to have been worn out rather by terror and anxiety. "On opening the belly," Hadfield says, "my first attention being of course directed to the stomach, I found the knife beginning to protrude through a Gangrenous opening about two inches and a half from the beginning of the duodenum, on which part the knife had lain. After opening the stomach, I found that the point of the knife rested on that part of the greater curvature, almost exactly opposite to the cardia, and had likewise very nearly perforated the coats. * * * The handle of the knife was completely dissolved, the rivets had disappeared, and a considera- ble portion (at least one-third) of the blade also. What was left appeared exceed- ingly rusty and black." This knife is in the Museum of the Royal College of Surgeons. In the same collection are some knives voided by a soldier in St. George's Hospital. 1744. Bulky bodies are most commonly retained in the stomach and at the ileo-colic valve. They may remain in the stomach a considerable time without causing symptoms, which, however, they easily produce in the intestinal canal, even if they be not fixed. The symptoms especially depend on the stoppage of the alimentary canal, or on the inflammation and injury which the foreign body produces by its peculiar form. In (he first case symptoms of ileus arise ; in the second, more or less severe enteritis. Oxidizable metals for example; copper coins produce no peculiar symptoms, as their oxidation, whilst resting in the alimentary canal, is exceedingly slow and not to that extent, which produces dangerous effects {a) ; indeed, in general, they are not long enough re- tained. [In the College Museum there is a very interesting preparation from a woman who had long suffered under symptoms of gall stones, and at last died exhausted. On examination, the gall-bladder was found thickened, contracted, and both it and the liver intimately adherent to the duodenum and adjacent organs. Between the gall-bladder and duodenum was a large ulcerated ragged opening of communication, through which a large gall-stone had passed, and, getting into the ileum, had blocked it up. Above this part the gut was distended with air and biliary fluid. In the Museum at St. Thomas's there is a portion of small intestine from a child, which is in two or three parts completely filled with lumps of hardened stool, in appearance resembling album Greecum, the result of quantities of carbonate of magnesia, which becoming entangled with the mucus of the bowel, had formed complete plugs of an inch or more in length. The College Museum also possesses an example of cherry-stones lodged in the caecum, which had been swallowed by a boy twelve years of age, at least sixteen months before his death, during which time he continually suffered from symptoms of chronic enteritis. Langstaff (b) gives an account of a madman who swallowed a silver table-spoon in October, 1827. Soon after his health gradually declined. Although he lived abstemiously his digestive organs were disordered; he suffered from dyspepsia,and frequently complained of an acute pain in the region of the caecum; and he persisted in declaring that all these symptoms were occasioned by the spoon he had swal- lowed. His account was disbelieved, especially as cautious examination of the belly was made without detection of any foreign body. He continued to suffer from the effects of pain in the situation of the caecum and colon, and frequently said he felt the motion of the spoon. He was teased with diarrhoea, and the evacuations were often mixed with blood and pus. Symptoms of diseased liver came on, and were followed by ascites and oedema of the lower limbs. Under these circumstances Langstaff tapped him, drew off a bucketful of water, and, as he was "greatly emaciated, I was induced," says Langstaff, " to carefully examine with the hand if I could feel the spoon, when, to my astonishment, I detected a solid suhstance in (a) Claude Rene Drouard, Experiences (b) Catalogue of the Preparations &c, et Observations sur 1'EmpoUonement par constituting the Anatomical Museum of POxide de cmvre (ver-de.gris.) PHris, 1802. George Langstaff. London lfc42 Svo. Orfila, Traite de Poisons, vol. i. p. 243. p. 228-32. IN THE STOMACH AND INTESTINAL CANAL. 105 the situation of the caecum, which induced me to believe that it was the spoon he had swallowed." He died about twenty months after, and on examination it was found that "the mucous coat of the stomach, as well as the duodenum, jejunum, ileum and caecum were more vascular than natural, and there were evident signs of their having been ulcerated on different portions, and that nature had put a perfect stop to the ulcerative process, by uniting the boundaries to the submucous tissue. The greatest degree of mischief had been effected by the passage of the spoon through the ileo-caecal valve, which was greatly dilated and the circumference thickened. The mucous coat of the caecum was nearly destroyed by ulceration. The spoon was found in this intestine, with the bowel downwards, where it had formed a large sac, which prevented its passage into the colon." The preparation is now in the Museum of the College of Surgeons.] 1745. Pointed bodies, when they remain hanging in the walls of the intestines, excite inflammation to such extent as to produce union of the surface with the peritoneum or any other part, so that when suppuration takes place by the continued operation of a foreign body, it may make its way in different directions, and proceed either to the surface of .the body, or even into any other cavity, as, for instance, into the bladder. [In rare instances a foreign body will make its way through the walls of the in- testine and belly, as in the case of the boy ten years old, from whom plum and cherry stones were discharged by an abscess communicating with the gut, and which are in the College collection.] 1746. In order to protect the stomach and intestinal canal against the effects of any such body, mucilaginous ensheathing food, and especially antiphlogistic treatment and purgatives, to hasten the passage of the foreign body through the alimentary canal, must be employed. [This is the ordinary practice usually employed; but I am not sure that the late Sir Francis Chantrey's proceeding under similar circumstances is not preferable. He had accidentally swallowed the gold fastening of one of his teeth, and, being much alarmed, came to my friend Green, to consult with him about the matter, at the same time suggesting the propriety of eating freely of suet pudding, with the hope of entangling the little gold plate, and favouring its passage through the bowels. Green saw no particular objection to this proposition, and accordingly a due quantity of the medicinal pudding was swallowed. Nothing more was heard or seen of the tooth-plate, and whether passed or not is unknown, but it never gave any inconvenience.—j. f. s.] 1747. If there be a foreign body in the stomach, or in the alimentary canal, which will not pass off by the usual wTays, and if it cause great danger to life, it must be removed by cutting into the stomach {Gastroto- mia) or into the intestine {Enteromia.) To decide on this very dangerous operation is always extremely difficult; it should only be undertaken when most positively called for by the situation of the foreign body, and on this point the symptoms are very doubtful. The intestine in wrhich the foreign body is may be far from the wall of the belly. As long as no very severe symptoms occur, the operation should not be rashly decided on; and if they have already set in, the result of the operation is the more doubtful. Gastrotomy has, however, been performed success- fully (a). Delpech (6) considers that there never can be such certainty of the situation of a foreign body in the stomach and intestinal canal as to decide on gastrotomy or en- terotomy. If there be a swelling, with fixed pain, the treatment should be confined only to a superficial cut, when the skin is distinctly pressed up by the suppuration, (a) Baldinger's Neues Magazin filr Aerzte, vol. xiii. p. 567.—Rust's Magazin, vol. vii. pt. i. (b) Precis Elementaire, vol. ii. pp. 67, 68. Vol. hi.—10 106 FOREIGN SUBSTANCES IN THE STOMACH, &C because there is no certainty to what extent union is effected, and whether extrava- sation of fecal matter can be prevented. There is a remarkable case in which a fork having been swallowed, excited sup. Duration, and by enlarging the opening of the abscess, was removed (a). For the removal of poison from the stomach, Read's or Weiss's, or Graham's stomach-pumps may be employe^. [Barnes (6) quotes from Becker the case of a young peasant, who on 29th May, 1635, whilst endeavouring to produce vomiting with the handle of a knife, let it slip 'from his fingers, and pass into his stomach. He was much frightened, bat able to go about his usual occupation. It was, however, determined to remove the knife by operation, which was done on the 9th of July following, by a surgeon and lithotomist, named Shoval. " A straight incision was made in the left hypo- chondrion, two fingers'-breadth under the false ribs; first through the skin and cel- lular membrane, then through the muscles and peritonaeum. The stomach subsided, and slipped from the fingers, which prevented it from being immediately seized; but it was at length caught hold of with a curved needle, and drawn out of the wound. A small incision was then made into it upon the knife, which was then easily extracted. The stomach immediately collapsed. After the external wonnd had been properly cleansed, it was united with five sutures, and tepid balsam poured into the interstices. Tents impregnated with the same balsam, and a cataplasm of bolar earth, the white of egg, and alum, were then applied." (p. 324.) Two sutures were removed next day, on the following day, two more, but the fifth is not noticed. On the fourteenth day after the operation, the wound had healed. Dr. Oliver (c) saw this knife at Konigsberg in 1685, and says,it was six and a half inches long. The patient completely recovered.] [See White's Case of Excision of a silver spoon from tbe Intestinal Canal, in the N. Y. Med. Repository, vol. x. p. 367. 1807.—g. w. n,] 1748. If the stomach contain nothing but the foreign body, it must be moderately filled, before proceeding to the operation, with muci- laginous fluid for the purpose of bringing it near the wall of the belly {d). If by feeling, the position of the foreign body can be distin- guished, the cut should be made upon that part: but under other cir- cumstances, upon the front wall of the stomach, an inch below the sword-like process of the breast-bone, to an inch and a half above the navel, about three quarters of an inch to the left of the white line, that the cut may be between the great and little curvature of the stomach. The wall of the belly is to be cut through with some careful strokes of the knife ; and then the stomach being laid bare, search is made for the foreign body, and a knife thrust into the stomach at the proper place, and the wound enlarged by a button-ended bistoury. The foreign body is then to be sought for with a pair of forceps introduced upon the forefinger of the left hand, taken hold of, and drawn out. The further treatment must be according to the rules laid down for wounds of the stomach {par. 541.) Hevin also proposes piercing the front wall of the exposed stomach with a grooved trocar, and to enlarge the wound upon it right or left. 1749. In enterotomy, the wall of the belly should be cut into where the foreign body is distinguishable, though if possible, on that part where the epigastric arteries can be avoided, search made with the finger for the position of the foreign body, the intestine containing it drawn into the wound, and then sufficiently cut into for the removal of (a) Salzburg, Med. Chir. Zeitung, July, 183S, p. 14. (6) Above cited. (c) Phil. Trans., vol. xxii. p. 1408. 1700-01. (d) Hevin, in Mem. de l'Acad. de Chirurg., vol. i. p. 598. FOREIGN BODIES IN THE RECTUM. 107 the foreign body. The further treatment is the same as in wounds of the intestine (par. 529 and the following.) Cutting into the intestine has been proposed for stricture and closure of the large intestines, for unrelievable collection of stools, for ileus and volvulus, in which cases, an artificial anus may be at the same time formed (par. 1616.) Although in such cases the operation may be successfully performed (a), yet on account of the uncer- tainty of the cause,and of the actual seat of the disease, as well as on account of the symptoms, to a great extent, an unsatisfactory issue to the operation, is so pro- bable (b), that practitioners are rarely inclined to it. V.—OF FOREIGN BODIES IN THE RECTUM. Morand, Collection de plusieurs Observations singulieres sur des corps etrangers, les uns appliques aux parties naturelles, d'autres insinues dans la vessie, et d'autres dans le fondement; in Mem. de l'Acad. de Chirurg., vol. iii. p. 606. von Walther, Beobachtung eines fremden Korpers von ungewohnlicher Grosse im Mastdarme; in Journal fur Chirurgie und Augenheilkunde, vol. i. p. 435. 1750. Foreign bodies may be introduced through the anus into the rectum, either voluntarily or accidentally, in making a careful examina- tion for certain things; or bodies which have been swallowed, after having passed through the bowels, may remain a longer or shorter time in the rectum; the passage of the swallowed body, however, in general causes no difficulty, as it is involved in a thick mass of stool. If the foreign body in the rectum excite symptoms they depend on its peculiar form or its great size. [(1) Phillips (c) mentions the case of an old man brought into St. Mary-le-bone Infirmary, who was delirious, and complained of having a stick in his rectum, and being unable to sit up without pain; but as no other information could be obtained about it, and no stick could be detected on examining the bowel, it was believed he was labouring under some delusion. A clyster was however given, but no stick was passed. On the third day he died, and on examination,^ six inches above the anus, was found the inferior extremity of a stick, which was about as thick as an ordinary, indicator finger; it was' covered with its bark, and carefully rounded at each end. Its superior extremity had passed through the sigmoid flexure of the colon into the peritoneal cavity to the extent" of four inches. The peritonaeum was highly inflamed through its whole extent, but there was very little thickening about the,tissues in the immediate vicinity of the perforated point. There was no appear- ance of disease in the rectum." McLaughlan (d) relates the history of a Greenwich pensioner, aged forty-nine, who having introduced an immense plug of wood fitted to the anus, for the purpose of stopping a diarrhoea, fell accidentally upon a stool, and forced it up into the gut. Eight days after he applied for assistance, having in the meanwhile suffered se- verely from continual efforts to void his stools and urine, which last was done with great difficulty. The whole belly was considerably enlarged, and felt knotty from the stools so long retained. The end of the forefinger could barely reach the plug on account of the inflamed and swollen state of the gut, which had begun to suppu- rate. The ordinary instruments were unavailing for its removal, and a peculiar pair (a) Velse, C. P., Dissert, de mutuo Intes- ture du bas-ventre dans les cas du volvulus tinorum ingresu. Lugd. Batav., 1742.— ou de l'intussusception d'un intestin; in Odier, Manuel de Medecine pratique. Ge- Mem. de l'Acad. de Chirurg., vol. iv.—Hk- neve, an xi. benstreit's Zusatze zu Bell's W. A. K., (b) Hoegg, A., Observationes medico-chi- vol. ii. p. 359.—Fuchsius ; in Hufeland's rurgicae. Jenee, 1762. Observ. iii.; in San- Journal, 1825, Feb., p. 42. difort, Thesaurus Dissertationum, vol. iii. (c) London Med. Gaz., vol. xxix. p. 846, See also, Leclerc, D., Ilistoire de la Mede- 1842. cine, p. i. 1. iv. ch. vi.—Hevin, Recherches (d) Ibid., vol. xxx. p. 462. 1842. Historiques sur la Gastrotomie, ou l'ouver- 108 FOREIGN BODIES IN THE RECTUM. of forceps were invented for the purpose, and fitted upon it with a screw. The ope- ration was very painful and required much force. In the course of a fortnight he completely recovered. . . A case is reported by Johnson (a) of a man who died immediately after being admitted into King's College Hospital; he had been labouring under obstruction of the bowels for five days, having eaten a large quantity of peas on the previous day; and during the last three days had also suffered from retention of urine. During the whole time he had had severe pain in the belly, costiveness, and bilious vomiting; purgatives were given without relief; and when admitted he was much debilitated, his features pale and shrunken; skin cold, and pulse feeble. On examination, the bladder was found distended, its base nearly at the brim of the pelvis, and its top reaching to the navel. The intestines were distended with air; but the rectum contained upwards of a pint of gray peas, which had been swallowed dry and al- most without mastication, and had not undergone any other alteration than becoming swollen; some were mixed with stool in the colon, but the greater number were on the rectum, where they formed a solid mass, occupying almost the entire pelvic cavity, pushing up the bladder and prostate, and compressing the urethra, so that there was considerable difficulty in passing the catheter. (2) Brodie (b) mentions the case of a person who had obstruction of the rectum, caused by a piece of apple core which he had swallowed on the day previous. Welbank tells me that on a similar occasion he pulled out a piece of vertebra and rib about an inch and a half long, part of a mutton chop which had been unwittingly swallowed.] 1751. The symptoms occurring under such circumstances are, ob- struction, or entire prevention of passing stools, very severe tenesmus, great inflammation, and swelling of the inner wall of the rectum, extend- ing to the neighbouring parts and to the bowels, violent fever, tympanitis, and the like. The danger is always great, and the foreign body must be removed as quickly as possible. The removal is often exceedingly difficult, on account of the seat and form of the foreign body, and the degree of inflammation and spasmodic contraction of the sphincter. [Abscesses by the side of the rectum are occasionally formed by hard substances, which have been swallowed, making way through its wall. Brodie (c) mentions an instance in which a very large abscess was found; it was opened, and sticking across it was a long fish-bone, which he extracted. Green tells me another instance of a female, in whom the abscess was so distended with pus, that when punctured it flew across the room ; from it part of, the pelvis of a snipe was removed. But still more serious consequences than abscess occasionally happen when a foreign body remains fixed in the rectum; it may cause complete closure of this gut, as in a case which occurred to Coulson. The woman, previously in good health, was thirty-four years of age, and between the fourth and fifth month of her pregnancy, when she was attacked with sickness, constipation, pain, and distension of the belly. These symptoms increased in severity, faecal matter was rejected from the stomach, the belly became more distended, and no relief from the bowels could be obtained, injections which were attempted to be thrown up the rectum, being immediately ex- pelled. She gradually sunk, and on the ninth day from the commencement of the attack, died. On examination, the colon was found exceedingly distended, especially its descending part, and between three and four inches from the anus, a foreign body, believed to he a small portion of fish-bone, found adherent to the lining membrane of the rectum, and in this situation pressed on by the gravid womb. Immediately below the bone, the gut was completely closed to the extent of three inches. The preparation is in the College Museum.] 1752. When the position of the body in the rectum has been ascer- tained by the introduction of the left forefinger oiled, a pair of polypus or stone-forceps are to be introduced upon it, the foreign body seized and withdrawn. The removal may be always facilitated by injecting oil (a) London Med. Gaz., vol. xxx. p. 605. (c) London Med. Gaz., vol vii d 27 183G (6) Ibid., vol. xvii. p. 27. 1836. ' P* '*'•louu FOREIGN BODIES IN THE LARYNX AND WINDPIPE. 109 into the gut. In violent inflammation, blood-letting should be resorted to, and in spasmodic contraction of the sphincter, suppositories, with the addition of extract of belladonna or hyoscyamus. In a case in which the size of the foreign body was very great, a pair of forceps with a moveable lock were employed, so that each blade could be separately introduced (a). In case of a very frangible body, as glass and the like, in which danger was dreaded from its pieces, the hand of a child was employed for its removal {b). The use of the various anal specula can render easy the grasping foreign bodies ; but the force accompanying the use of these instruments, renders them dangerous, if there be much inflammation. In these cases it is better to cut through the sphincter ani, and thereby relieve the obstruction which prevents the removal of the foreign body. (Delpech.) Marchettis (c), in a case in which a swine's tail, with the thick end upwards, had been introduced into the rectum, used a hollow tube, which protected thjp inner membrane of the rectum from injury. [Custance (d) mentions the case of a man who fell on an inverted blacking pot, and had the whole of it forced up the rectum. Attempts were made for an hour and a half to dilate the sphincter, and remove it with forceps, but in vain. The small end of an iron pestle was then introduced, till it touched the bottom, and being held there firmly, was struck with a flat iron. At the second blow, the pot was broken into several pieces, which were removed piece by piece with the forceps, or with the fingers. Next morning he laboured under severe intestinal inflammation, with incessant vomiting and excruciating pain over the whole belly; and he died at night. The pot was two inches and three eighths at the brim, an inch and a half at its base, and two and an eighth in depth. Lawrence, had a case in which a man had broken the neck of a wine-bottle into his rectum; he gradually dilated the sphincter, introduced his whole hand, and re- moved it.} VI.—OF FOREIGN BODIES IN THE LARYNX AND WINDPIPE. Hevin, Precis d'Observations sur les Corps etrangers arretes dans l'GHsophage,. et dans la Trachee-artere, etc.; in Mem. de l'Acad. de Chir., vol. i. p. 565. Louis, Memoires sur la Bronchotomie—Second Memoire sur la Bronchotomie, ou l'on traite de Corps etrangers dans la Trachee-artere; in Mem. de l'Acad. de Chir., vol. iv. p. 455. De la Martiniere, Observations sur un Corps etranger qui percoit la Trachee- artere; in Mem. de l'Acad, de Chir., vol. v. p. 521. Lescure, Sur une portion d'Amande de noyau d'abricot, dans la Trachee-artere ; in same, p. 524. Suite d'Observations sur les Corps etrangers dans la Trachee-artere; in same, p. 527. Porter, Will. Henry, Observations on the Surgical Pathology of the Larynx and Trachea, &c. Dublin, 1826. 8vo. Stokes, William. M.D. A Treatise on the Diagnosis and Treatment of Diseases of the Chest, Dublin, 1827. 8vo. Wendt, Historia Tracheotomiae. Vratislav., 1774. Ficker, De Tracheotomia. et Laryngotomii. Erfurt, 1792. Desault, C3uvres Chirurgicales, par Bichat, vol. ii. p. 255. Klein; in Chirurgisch. Bemerkung. Stuttg., 1801; in von Siebold's Chiron., vol. ii. p. 649; in von Graefe und von Walther's Journal, vol. i. p. 411; vol. vi. p. 225. (a) Messerschmidt ; in Waltber, above (c) In Morand. cited. (d) London Medical Gazette, vol. iv. p. 18. (6) Nolet ; in Morand, above cited. 1823. 10* 110 FOREIGN BODIES Michaelis ; in Hufeland's Journal, vol. ix. pt. n.; vol. xi. pt. ill. Pelletan, Memoire sur la Bronchotomie; in Clin. Chir., vol. 1. p. l. Lawrence, Will, On some Affections of the Larynx, which require the operation of Bronchotomie; in Med.-Chir. Trans., vol. vi., p. 221. [Case of a shot in the Trachea by Hopkins, in Potter's Medical Ly- ceum.— G. W. N.] 1753. Foreign bodies usually get into the windpipe, when during the act of swallowing, the epiglottis is raised by speaking, laughing, and the like, or when they are thrown into the mouth. The symptoms produced depend on the obstructed passage of the air, and the irritation of the lining membrane of the windpipe. Immediately there occurs a severe con- vulsive cough, with danger of choking, with a whistling and rustling in the throat, which sometimes relaxes for a space; the patient points to the seat of pain with his finger, has more or less painful effort in swallowing and imbreathing; his voice is altered and becomes hoarse, or is com- pletely lost; by the obstructed return of the blood from his head, the face at last becomes puffy and bluish, the eyes start out, the veins of the neck are swollen, and above the collar-bones there appears an emphysematous swelling. These symptoms sometimes continue with the same violence, sometimes cease, but recur at irregular periods; occasionally only some of them diminish, considerable pain, oppression., and difficulty of breathing remain. The consequences specially to be feared from foreign bodies in the windpipe are, suffocation, if the entianee of the air be completely prevented; emphysema of the lungs if the position of the body prevent the escape of the air; inflammation of the windpipe and lungs with their outlets, and apoplexy from the collection of blood in the brain. [Porter (a) well observes:—"This accident never happens at the time it is generally considered as most likely to occur, namely, in the act of swallowing. When a person is engaged in the performance of this function the root of the tongue is depressed, whilst the larynx is elevated: the epiglottis is thus mechanically thrown as a bridge across the larynx, and so effectually closes it that the smallest morsel, or even a drop of water, can find no admission. * * * But it is different when a man attempts to draw a full inspiration whilst any foreign body is within reach of the current of air about to pass into the lungs. At this time the epiglottis is raised, the rima glottidis is distended, and every thing appears to favour the entrance of the air, and, of course, of whatever it bears along with it. Thus, a person holding a sup of wine in his mouth to enjoy the flavour, incautiously attempts to breathe, a drop of the fluid enters the larynx, it produces great irritation and the spasmodic cough, that ensues throws it out with great violence, perhaps even through the nostrils." (pp. 184, 185.) One of the most remarkable instances of a foreign body getting into the windpipe without passing through the rima glottidis is mentioned by De la Martiniere (b). A child, nine or ten years of age, amusing himself with cracking a small whip, was suddenly seized with extreme difficulty of breathing, and soon exhibited all the symptoms of approaching suffocation. He complained, by gesture, of some impedi- ment in the trachea. The surgeons who saw him, aware that he had never been left alone, and that he could not have put any thing into his mouth, did not suspect the existence of a foreign body impeding respiration." He was bled, the throat ex- amined, and an.oesophageal bougie passed, without making any discovery. The symptoms became more urgent, and De la Martiniere saw him an hour after. "On examining the neck externally, I found," says he, " a small red spot on its fore part, like the middle of a flea-bite, immediately below the ericoid cartilage, and beneath it was felt deeply a little circumscribed ganglion as large as a lentil, corres- ponding to the red spot, and of unnatural brightness; the sensation could not have (a) Above cited. (b) Mem. do l'Acad., above cited. IN THE LARYNX AND WINDPIPE. Ill been more distinct through the thickness of the parts. I at once determined to cut through the skin and fat upon this spot. The finger having been introduced into the wound, and touehing the tubercle, which was close to the windpipe, I deepened it with a second stroke of the knife, and laid bare the cartilaginous rings of that tube. I felt with my nail an irregularity, projecting at least a line above its convexity, and endeavoured in vain to seize it with the dressing forceps. Luckily I had with me a pair of hair-nippers, and with these caught hold of the body, which I drew out, and, to my great surprise, found it to be a large copper pin without a head, about an inch and a quarter long, which had pierced through the windpipe from left to right." The child got well in a few days.] 1754. The difference of the symptoms depends on the particular seat, form, and condition of the foreign body. If situated in the rima glottidis, and completely closing it, the patient is suffocated, if not quickly re- lieved, or the foreign body do not change its place by the violent inspi- ration and expiration, which, however, is rarely the case, on account of the spasmodic contraction of the rima. If the rima be not completely closed by the foreign body, violent convulsive cough comes on, and the patient points to the seat of the body with his finger. A foreign body, if not of large size, may remain lying in either of the laryngeal ventricles. Its symptoms are at first less severe, but the continued residence of the foreign body will, in the end, be fatal (1). If it be loose in the windpipe, it moves up and down with every inspiration and expiration; symptoms come on at intervals; the pain is severe; changes its place ; the cough is frequent and convulsive, so that, in very rare cases, the foreign body is coughed out; danger of suffocation occurs if it b*e forced up against the rima glottidis. Foreign bodies rarely drop into either bronchus (2). Pointed rough bodies cause violent symptoms; the mucous membrane of the windpipe inflames, swells, and the passage narrows where the foreign body is fixed. The same happens with those bodies which swell with moisture. In rare cases the foreign body, after remaining a long while in the air passages, and producing symptoms of phthisis, is thrown out, and the case terminates satisfactorily (3). [(1) A foreign body, to be lodged in the ventricles of the larynx, must be ex- tremely small; and I apprehend suchas are generally described as so situated are not so, but only in the body of the larynx, of which there are two examples in the Museum of St. Thomas's Hospital. In one a piece of mussel-shell lies lengthways in the left side of the larynx, with its upper end jammed into the base of the epi- glottis. I cannot get more information of it than that the child lived a fortnight after the accident. The other, a case related by Bullock (a), was a girl of six years, who swallowed a pebble. " She was seized with a most violent convulsive cough, so that she became black in the face and was nearly suffocated; the paroxysm con- tinued for half an hour and then subsided. The throat was examined, and an oesophageal probang introduced, but without, however, discovering any extraneous body. The three or four following days the child merely complained of a sense of soreness in the throat with nausea, which was accompanied by occasional slight paroxysms of cough with a copious mucous expectoration; she was also hoarse, but had no pain or difficulty in deglutition. Aperients and an emetic were prescribed; she was not benefited, and, as. she still persisted that the stone remained in the throat, was again, on the fifth day, very carefully examined, yet there did not appear to be any evidence of its existence either in the oesophagus or trachea." As she had not had hooping cough and was constantly playing with children who were labourino- under that disease, it appeared to warrant the conclusion that no foreign body had passed either into the oesophagus or trachea, and that the cough was among the first symptoms of a severe form of pertussis. At the end of the fifth day she had marked (a) London^Medical Gazette, vol. xviii. 1836. 112 FOREIGN BODIES symptoms of inflammation of the mucous membrane of the bronchi, namely, cough, generally occurring in paroxysms six or seven times a day, attended with a kind of whooping inspiration and a copious expectoration of tenacious mucus; the hoarseness was likewise increased, while over the trachea and upper part of the chest there was a loud mucous rattle, which was in part sonorous." Leeches and calomel, and antimony were used for some days, and in a month from her first attack she was stated to be "quite well," having regained her flesh and healthy appearance. A fortnight after this, however, " she was attacked with symptoms of pneumonia," and she died in twelve days, "eight weeks from the supposed accident; but from the time she was reported quite well to the day of her death there was no return of the convulsive cough nor any uneasiness about the throat. On the day of her death, however, she again said she could still feel the stone, and in the same place as at first. Examination.—On laying open the larynx and trachea a quartz pebble was exposed, lying partly in the cricoid cartilage and partly in the trachea, of the size of a horse bean, of irregular figure and smooth surface ; it was retained in its situation by a layer of apparently organized lymph of very considerable thickness. On re- moving the stone the mucous membrane was in a state of ulceration (and the front of the thyroid and cricoid cartilages bare.—j. f. s.) The calibre of the tube was so nearly obstructed by the presence of the stone and lymph as to render it difficult to pass an ordinary-sized probe downwards. The whole of the mucous membrane of the trachea was thickened and its vessels congested. About a pint of turbid fluid was in the right pleura, containing flakes of adventitious membrane, with which the pleura pulmonalis of that side was also covered. Nearly the whole right and the lower part of the left lung were in the several degrees of hepatization and purulent infiltration, (p. 952.) (2) When the weight of the foreign body has carried it low down into one of the bronchi, most commonly the right on account of its larger size, as first noticed by Key, it may block up the passage so completely that no air, or but little, can pass into the lung below it, and consequently it remains fixed by its own gravity, causing pain in the chest opposite the part where it is lodged, which is increased on deep inspiration, and is accompanied with " a catching." Violent cough and a disposition to vomit, or actual vomiting, occur immediately after the accident, but after a time subside, and an occasional dry cough comes on at irregular periods, and in the inter- vals the patient may be tolerably well and able to follow his ordinary occupation, or the symptoms may become more urgent, may be accompanied with repeated attacks of haemoptysis and terminate in phthisis, even although the foreign body have been retained weeks or months. Some remarkable cases of this kind will be presently referred to. (3) The time which a foreign body, after the first severe symptoms have passed by, may remain lodged in the air passages varies very considerably. The longest period of which I am aware is that of the female mentioned by Sue (a), who when in her ninth year, had the rump-bone of a pigeon slip into her windpipe; she be- came subject to attacks of haemoptysis and other symptoms of pulmonary disease, but without wasting, till her twenty-fourth year, when she began to decline rapidly. Two years after she threw up the bone in a violent fit of coughing; but she died eighteen months after with profuse pumlent expectoration. Dupuytren (b) gives an account of a man who lived ten years, after a small coin had got into his air-tube, and on examination it was found imbedded in a tubercular cavity in the lung. Louis (c) also relates another case, in which after swallowing a louis-d'or, a man lived six years and a-half, and then died with his right lung'completely destroyed by suppuration. My friend Sutton, of Greenwich has mentioned to me a case of haemoptysis, which he attended many years since. The man had frequent attacks for more than a twelvemonth, from each of which, however, he rapidly recovered. Upon the last occasion, he was summoned suddenly to see the man who was said to be in a dying state. On his arrival he found the patient had had a very severe attack of dyspnoea, and threatening suffocation, from which, however, he had been immediately relieved on rejecting from his windpipe a common lathe nail, much cor- roded. The man was a plasterer by trade, and now remembered that some time before first requiring Sutton's assistance, he had swallowed a nail whilst lathing (a) Mem. de l'Acad. de Chirurgie, vol. v. (c) Mem. de l'Acad. de Chir, vol. v. p. 533. 529. (6) Lecons Orales, vol. iii. p. 584. IN THE LARYNX AND WINDPIPE. 113 a ceiling, but had thought no more about it till it was thrown up. He died some years after of diseased lungs. Dr. Paris (a) relates the case of a girl twelve years old, who " having put a small cowrie shell in her mouth, was seized with a violent choking fit, in consequence of its having been supposed to have gone the wrong way in the act of swallowing it. The spasmodic paroxysm was described as most alarming, and continued for several seconds, which induced her father to thrust his finger with considerable force down her throat, which afforded immediate relief, and therefore convinced him that he had thrust the foreign body into the oesophagus, and that it had passed into the stomach. * * * In the course of four or five days a slight cough came on, but it was not characterized by any symptom which would lead to the suspicion of it having been provoked by the presence of any foreign body in the air passages, and this opinion was confirmed by its speedily yielding to the ordinary treatment." Between three weeks and a month after she had " a return of the cough much more violent than usual, and accompanied with slight haemoptysis. This, however, again subsided, and she remained for many months in perfect health; her breathing was never disturbed, she indulged in her usual active habits and daily exercise, and declared that she was perfectly well. * * * About twelve months after, she had danced at a ball during the whole evening, and at its conclu- sion, in the act of moving briskly, she was suddenly attacked by a violent spas- modic cough, which threatened suffocation, when by a sudden and convulsive expi- ration, a substance was ejected from her mouth with such force as to be carried to a considerable distance. This proved to be the remnant of the shell, the animal prin- ciple of which had disappeared, and its earthy matter alone remained." (pp. 116,17.) In the younger Traver's case (b), a girl of six years, who was suddenly thrown back whilst eating cherries, " was immediately seized with a violent fit of choking and every symptom of impending suffocation. This condition lasted an hour, and then she fell asleep." On the next day she had some spasmodic pain in the chest, and on the following " morning the breathing was very difficult, and other symp- toms of inflammation present,-" which were relieved by blood-letting, a calomel and jalap purge, and calomel and opium. On the afternoon of the fourth day " she had a violent convulsive seizure, with cough, small quick pulse, a livid surface, suffused eye, and every sign of threatened suffocation. It was stated in evidence of the violence of the spasm, that the stools and urine 'flew' from the child during these attacks." She grasped and pulled her throat in a peculiar manner, " crying in a half whisper 'take it out! take it away!' The spasm subsided after two hours' continuance," and a few hours after she was so tranquil as to lead to the belief |'that no stone could have passed into the trachea," In the middle of the follow- ing day the fit recurred with "violent jactitation and abundant flow of frothy mucua from the mouth. When it had subsided, the probang was introduced, and the child swallowed with greater facility." On the seventh day there came on a similar attack; on the thirteenth and from that time daily, till the nineteenth day, when Travers saw her, and she had then "frequent paroxysms of croupy cough, attended by great restlessness and the peculiar grasping of the throat." Under these cir- cumstances, he performed tracheotomy; but the stone was not thrown out; the breathing, however, became tranquil, and the cough also ceased. It returned, how- ever, on the twenty-sixth day, but less severely. Ahout six weeks after, the wound, which had been tented healed, and soon after " the child coughed incessantly, had night sweats, with loss of strength and appetite." In this condition she continued till the ninety-sixth day after the accident, when she threw out " the stone, together with a table-spoonful of pus, during a violent paroxysm of cough; having expecto- rated pus in small quantities for many days previous. From this time the cough never returned and the general health was soon re-established." (p. 108-12.) 1755. As foreign bodies in the oesophagus produce the same symp- toms as those in the windpipe, it is always necessary, by examination of the throat, by the introduction of a sound, with a piece of sponge upon its end to be sure of the oesophagus (1). Foreign bodies are only in very rare instances, thrown out by violent coughing: on this account a severe emetic or artificially excited sneezing increase the danger (2). la) Med.-Chir. Trans., vol. xxiii. 1840. (b) Ibid. 114 FOREIGN BODIES The only remedy for the certain removal of the foreign body is opening the windpipe, (Bronchotomia, Tracheotomia,) or opening the larynx, Laryn- gotomia.) This operation must be undertaken as quickly as possible, because if put off, such symptoms as violent inflammation of the lungs and windpipe, emphysema of the lungs and the like arise, which even after the removal of the body may cause death. The operation is in all cases required, where suffocation presses, or an asphictic condition has set in ; further, if dangerous symptoms occur from time to time, and the foreign body be observed rolling up and down in the windpipe; or if fixed pain point out its seat. But if the patient be free from all these symptoms, and the seat of the foreign body cannot be discovered, we must wait till there are symptoms of change in its situation, and a possi- bility of its removal. [(1) In reference to this subject Stokes (a) mentions one instance in which a piece of money lodging in the oesophagus produced croupy breathing and laryngeal symptoms. And in his Lectures he used to speak of another case in which such symptoms were produced by a foreign body (a plum-stone) in the oesophagus, that his first impulse was to perform tracheotomy with his penknife. An oesophageal bougie was, however, introduced, and the substance having been pushed into the stomach, the symptoms ceased, and a day or two after the plum-stone, with which the child had been known to be playing previous to the accident, was voided by stool (b). (2) Occasionally it may happen that although violent fits of coughing having failed to expel the foreign body from the windpipe, yet by some accidental change in the patient's position, the foreign body is removed from its lodging place, and is then thrown up with little effort. Such seerns to me the explanation of Cock's case (c) of a sixpence slipping down the throat, and at first lodging in the larynx; "violent coughing, with the most distressing sense of suffocation, immediately took place, and during the paroxysm he threw up a quantity of blood. On his admission he was still struggling for breath, coughing incessantly, and suffering great pain and irritation, which he referred to the larynx, where the coin appeared to have lodged." Shortly after "the sixpence had left the larynx, and descended into the trachea ,• its change of position being immediately followed by an abatement of the previous urgent symptoms. He still coughed almost incessantly, stated that he could feel the sixpence moving up and down the windpipe, and complained of pain and soreness in the chest in the seat of the right bronchus, and also just below the larynx." Towards the end of the same evening the symptoms subsided, and he went to sleep. On the following day he was in much the same state, and "as long as he remained calm and quiet, he complained of nothing but a feeling of general sore- ness along the larynx and windpipe." The same evening the sixpence was thrown out without surgical aid. "I was asleep," said the patient, "and dreamed I was drinking a pot of porter, and the attempt to swallow it made me cough. I awoke, and found the sixpence in my mouth." Cock observes:—"It is perhaps worthy of remark, and not destitue of practical interest, that the foreign body, which had retained its position during the most violent expiratory efforts, should at length be ejected, at a period when the muscles of the glottis were probably in a state of quietude, and being taken unawares, allowed its expulsion, under a gentle act of coughing." (pp. 554, 55.)] 1756. Opening the larynx or windpipe is also required to assist the entrance of the air into the lungs, when it is obstructed under any other circumstances, and suffocation is dreaded; in great swelling or other degeneration of the structures about the throat; in diseased changes of the epiglottis; in great swelling of the tongue, if the danger cannot be relieved by bleeding, scarification, and the like; in fracture of the thyroid (a) Above cited, p. 265. (c) Medical Gazette, vol. i. New Series, (6) Wells ; in Diet, of Prac. Surgery, vol. 1845. i. p. 516. IN THE LARYNX AND WINDPIPE. 115 cartilage, if the dislocated pieces cannot be otherwise brought into place; in inflammation of the epiglottis {Angina laryngea); when foreign bodies are in the oesophagus, and cause suffocation ; in compression of the wind- pipe by tumours ; in gun-shot wounds of the throat, which, on account of the great swelling, are attended with danger and suffocation ; in drunken or suffocated persons; in croup, if the membrane.be loose and cannot be coughed up. According to Desault (a), in the greater number of these cases in which it is only necessary to assist the entrance of the air, the introduction of an elastic tube through the nostril renders the operation superfluous. No other person, however, but Desault holds this notion. Samuel Cooper (b) objects to it in drunkards and suffocated persons, and considers opening the windpipe to inflate the lungs, most efficient. However, the benefit of cutting into the windpipe, undertaken in this spirit, is not supported by precise reasoning. In Angina laryngea, which is characterized by difficult breathing, with pressing suffocation, very hoarse and only whispering voice, and frequently accompanied with pain in the oesophagus and difficulty in swallowing, without apparent swelling and redness of the throat, the operation must riot be long delayed, if relief be not soon afforded by general and local blood-letting, blisterings, and the like (c). In Angina membranacea, laryngotomy and tracheotomy are generally useless, because the mass blocking up the air-tube, is not. merely in the larynx, but extends through the whole windpipe and even into the bronchi (d). In more modern times, how- ever, many cases have been published in which this operation has been successful. Nevermann (e) has collected all the cases of laryngitis and trachaeilis, in which tracheotomy has been performed ; and the result is that out of one hundred and forty cases, twenty-eight have been cured, and one hundred and twelve died. Bretonneau (/) considers that tracheotomy can only terminate favourably, if the opening be made moderately large between the thyroid gland and breast-bone, and the free> entrance and escape of the air maintained by a sufficiently large and wide canula. At the same time he introduces calomel dry, or moistened with water, through the wound into the windpipe. In one case he succeeded: Trousseau (g) also recommends the introduction of a thick catheter, and scraping out the windpipe with a probang, and dropping in a watery solution of nitrate of silver, four grains to a drachm of water. Gerdy (h) also advises the in- troduction of a weak solution of lunar caustic. [Kirbv (i) is decidedly opposed to bronchotomy for croup; he says:—I have performed the operation myself on the child, and have seen it frequently done by others, and in no one case has the life of the patient been saved." (p. 63.)] 1757. The proceedings vary in laryngotomy and tracheotomy, in refer- ence to the special object desired, according as the entrance of the air is to be assisted, or a foreign body removed. 1758. In laryngotomy, after placing the patient's head in such a position as that his uneasiness shall be at least, and the front of the neck free and accessible, the skin is to be moderately stretched on both sides (a) Above cited. Journal, vol. xxix. p. 75,1828.—Beco.uer.el; (6) Diet, of Pract. Surgery, p. 1262. Bulletin dp Therapeutie, 1842, Jan., Feb. (c) Farre; in Med.-Chir. Trans., vol. iii. (/) Des Inflammations speciales du Tis- p. 84.—Percival, E.; Ibid., vol. iv. p. 29.— sumuqueuxet en paTticulier de la Diptherite, Wilson, Thomas; Ibid., vol. v. p. J56.— ou inflammation pelliculaire, connue sur le Arnold; Ibid., vol. ix. p. 31.—Hall, Mar- nom de Croup, d'Angine maligne, d'Angine shall ; Ibid., vol. x. p. 166.—Porter; Ibid., gangreneuse, p. 217—395. Paris, 1826. vol. xi. p. 114.—Wedemeyer ; in von Graefe 8vo. und von Walther's Journal, vol. ix. p. 107. (g) Journal des Connaissances Med.- (d) Sachse, vol. ii. p. 277; the best'writer Chirurg., 1834, June. on Croup. (h) Archives generates de Medecine, vol. (e) Berliner Med. Centralzeitung, 1836, v. p. 577, 1834.—Stilling; in Berlin Med. July.—Also, Cullkn, V., On the Causes of Centralzeitung, 1835, May 9. the Fatal Termination of certain cases of (i) Observations, cited at the head of arti- Bronchotomy; in Edinb. Med. and Surg. cle. 116 LARYNGOTOMY. with the fingers of the left hand, and the larynx at the same time fixed; a cut is then made lengthways, about an inch in length, the middle of which corresponds to the crico-thyroid ligament. A second cut divides the cellular tissue between the sterno-hyoid and sterno-thyroid muscles, and lays bare the crico-thyroid ligament; the bleeding must be stanched with a sponge dipped in cold water. The larynx is then to be fixed with a finger on each side, and the forefinger of the same hand placed on the upper third of the ligament; after which a lancet is thrust in, and a wound of sufficient extent made, which is to be kept open by inserting lint between the angle of the skin and of the muscular wound, and the whole covered with gauze, and the patient allowed to bend his head towards his chest. This method appears preferable to using the tracheotome and introducing a tube into the aperture made in the crico-thyroid ligament, for the tube always excites in- convenient, and frequently unbearable irritation, is frequently stopped up, and cannot be properly fastened. The cases in which cutting into the windpipe is performed are urgent, and the tracheotome cannot be sufficiently commanded. If the opening into the cricoid-thyroid ligament be sufficient, the cut must be lengthened through the cricoid cartilage. For the purpose of effecting expectoration, if much tough mucus collect, the wound must occasionally he held with the fingers, and the patient allowed to cough. If a canula be used, it should always be sufficiently large. For the purpose of avoiding an often not inconsiderable arterial branch upon the crico-thyroid membrane, we-must feel with the finger if the membrane be quite bare, and when it is exposed, we must endeavour to avoid it, for which purpose the mem- brane is to be divided transversely at the upper edge'of the cricoid cartilage. [Some persons are in the habit of introducing a tube into the larynx after having opened it. This as a general rule is quite unnecessary, as if there be any fear of the wound closing before the air can recover its usual course through the rima glottidis, it is better to cut out a piece of either the laryngeal or tracheal cartilage, as may be, according to Lawrence's recommendation. And it is also improper, as a fistulous opening will be formed, which on the subsequent removal of the canula, may con- tract so as to require a second operation, and often cannot be done without. If, however, such practice be adopted, it will be necessary that the instrument should be taken out from time to time to ascertain that it has not been corroded; for if not, it may break, and the part within drop down the windpipe, whilst that without falls from the wound, without notice. A case of this kind was admitted into St. Thomas's Hospital in December, 1844; a tube had been introduced about two and a half years previously, and on the morning of his admission whilst walking along the street, it slipped out broken. No symptoms of ^consequence, however, appeared till towards evening, when the breathing became difficult, and attended with a whistling noise; the veins of his head and face distended, and the surface covered with cold perspiration. My colleague and assistant, the younger Travers, therefore, thought it necessary to pare the edges of the opening, and dilate it upwards and downwards, upon a director. Some blood running into the windpipe caused violent expirations, and in one of them two fragments, which formed the remainder of the canula, were expelled, surrounded with a clot of blood, and the relief was immediate. Another canula was introduced. The patient did well; and the broken corroded instrument, is in St. Thomas's Museum. Occasionally it happens that after a severe cut throat, the aperture remains, from some cause or other, fistulous; and as the scar contracts, the passage for the air is so narrowed as to cause great difficulty of breathing, and require surgical aid. Ihad a case of this kind some years ago, in a Hindoo woman, who, in her voyage to this country, had attempted suicide, and nearly cut through the larynx, between the thyroid and cricoid cartilage. She had been very refractory, and the skin had turned over the lower edge of the wound, and become connected with the back of the organ, so as materially to diminish the passage, and cause her breathing to be very laborious, and with a loud hiss. As from the account given, these symptoms were daily becoming worse, I cut through the front of the cricoid cartilage vertically, TRACHEOTOMY. 117 and inserted a short but pretty wide tube, through which she breathed freely and did well, leaving the house some time after to return home.—j. f. s.] 1759. If laryngotomy be undertaken for the removal of a foreign body, the crico-thyroid ligament is, after the bleeding has been stanched, to be cut through its whole length, from the thyroid to the cricoid cartilage; and if this be insufficient to allow the foreign body to be removed or withdrawn through it, a director somewhat curved is to be introduced, by means of which a button-ended bistoury is passed in, and the thyroid cartilage sufficiently divided upwards in its centre, or the cricoid cartilage, and the upper part of the air-tube so far cleft as the removal of the foreign body may seem to acquire. 1760. After the opening is made, if the edges of the wound be gently drawn apart with blunt hooks by the assistants, the foreign body usually appears and is thrown out by coughing; but if this do not happen, its position must be sought with due care, and it must be removed with straight or curved forceps. The treatment, after removal of the foreign body, must be precisely similar to that already laid down for longitudinal wounds of the windpipe, {par. 467.) 1761. In tracheotomy, where the entrance of the air merely is to be assisted, a cut should be made through the skin and muscle on the mesial line of the windpipe, beginning below the cricoid cartilage and continued down to the edge of the breast-bone. The edges of the wound are to be held asunder with blunt hooks, the blood sopped up with a moist sponge, the cellular tissue and vascular net upon the third and fourth cartilaginous rings divided, and thus the windpipe laid bare. Bleeding is stanched by cold water, or, where possible, by tying the vessels; the lobes of the thy- roid gland, which are a little in the way, are to be turned aside, andtwTo or three rings of the windpipe divided vertically. The further treatment is the same as after opening the larynx. The same reasons against the use of the tracheotome and the introduction of a tube, which have been already given, (par. 1758) also apply here. Lawrence (a) advises, if after opening the windpipe, the introduction of the tube cannot be effected, to cut off half an inch through the cartilage, and to remove a small slip from the edges of the wound, so that the opening may continue to gape. 1762. If tracheotomy be performed for the removal of a foreign body, the air-tube must be exposed and cut into in the way just described, only the size of the cut must be proportioned to that of the body to be removed. The removal itself must be managed as in laryngotomy. [When the foreign body is lodged in the bronchus its removal should be first at- tempted by reversing the patient's natural position, and placing him upright, or nearly so', with his head downwards, and then striking his back or shaking the body smartly, by which it may be hoped the foreign substance will move from its situa- tion, and, dropping through the windpipe, be ejected at the rima glottidis. Of the two very interesting cases in which this practice was successfully adopted, Brodie's patient (b) had first attempted it on the sixteenth day after the accident, by "placing himself in the prone position, with his sternum resting on a chair, and his head and neck inclined downwards, and, havirfg done so, he immediately had a distinct per- ception of a loose body slipping forward along the trachea. A violent convulsive cough ensued. On resuming the erect posture he again had the sensation of a loose body moving in the trachea, "but in an opposite direction, that is, towards the chest." The experiment was repeated six days after, more completely; "he was placed, in the prone position, on a platform, made to be moveable on a hinge in the centre, so (a) Above cited, p. 249. (b) Above cited, Vol. iii.—11 118 TKACHEOTOMY. that on one end of it being elevated, the other was equally depressed. The shoulders and body having been fixed by means of a broad strap, the head was lowered until the platform was brought to an angle of about 80 degrees with the horizon. At first no cough ensued; but on the back, opposite the right bronchus, having been struck with the hand, the patient began to cough violently; the half-sovereign, however, did not make its appearance. This process was twice repeated with no better re- sult; and on the last occasion the cough was so distressing, and the appearance of choking was so alarming, it became evident it would be imprudent to proceed further with this experiment unless some precaution were used to render it more safe." Tracheotomy was therefore determined on two days after, and "in proposing this," says Brodie, " we had a twofold object; the one, that if the coin were-lodged in any part from which it might be safely extracted by the forceps, this method might be had recourse to; and the other, that, if relief could not be obtained in this*manner, the artificial opening might arfswer the purpose of a safety valve, and enable us to repeat the experiment of inverting]the body on the moveable platform without the risk of causing suffocation." The operation " being completed, some attempts were made to reach the coin With the forceps introduced through the opening. The contact of the instrument with the internal surface of the trachea, however, induced on every occasion the most violent convulsive coughing. The coin was not seized, nor even felt." The attempt was therefore given up for the time, and repeated five days after with no better success. He was left quiet for ten days to recover from the exhaus- tion he suffered, and the probe was passed occasionally into the wound to keep it open. At the end of this period, on the thirtieth day after the accident, " the patient having been placed on the platform, and brought into the same position as formerly, the back was struck with the hand; two or three efforts to cough followed, and pre- sently he felt the coin quit the bronchus, striking almost immediately afterwards against the incisor teeth of the upper jaw, and then dropping out of the .mouth. A small quantity of blood, drawn into the trachea from the granulations of the external wound, being ejected at the same time. No spasm took place in the muscles of the glottis, nor was there any of that inconvenience and distress which had caused no small degree of alarm on the former occasion, (p. 288-91.) The case did well. Macrae (a) did not make any opening into the air-tube of his patient, but, on the third day after the mishap, had him " strapped securely to a common chair, that he might be easily suspended from the rafters of the roof, with his head downwards, in order that his chest might be conveniently shaken bya rapid succession of sudden smart jerks, and that the weight of the bullet.might favour its escape from its seat in the lungs. He was kept depending as long as he could endure such an uncom- fortable position, and then placed in the horizontal posture for a few minutes to rest. When sufficiently recruited he was hung up again. Upon being taken down the first time he described the pain in his breast as having moved nearer to the top of his chest; and during the third suspension he joyfully exclaimed, " thanig a! thanig a,!" ("it has Come! it has come!" in the Gaelic language,) immediately after a smart shaking and a few convulsive retching coughs, and spat the little bullet from his mouth. The diameter of it is three eighth parts of an inch, having its surface ruffled by the chewing it underwent previously to slipping into the windpipe. He felt immediate relief from every uneasy feeling, except the dry cough and deep-seated pain in his breast, which continued rather sharp for two days, after which, and a dose of laxative medicine, he found himself restored to his former health, and by the end of the week pursued his usual avocations on the hill." (pp. 421, 422.) If this mode of treatment be insufficient to dislodge the foreign body from the bronchus, it will be necessary to attempt its removal by opening the windpipe and drawing it out with forceps. This operation was first performed, and successfully by Liston in 1833 (b), on a female of thirty-eight years, who " got a piece of mutton bone entangled in the glottis, whilst eating some hashed meat. By a great effort, during a fit of threatened suffocation, she succeeded in dislodging it; but it passed downwards into the trachea," * * * and lodged permanently under Ihe right sterno- clavicular articulation. An attack of bronchitis supervened, followed by cough and expectoration, and the inflammatory attack was repeated several times; from one of these she had just recovered. * * * The inspiration was somewhat noisy, and there (a) Ltston's Practical Surgery. Fourth p. 419.—Also Liston's own notice of it, in EdA\10^1846* ■ t . ,0000, , •■ his Practical Surgery; from which I have (b) Duncan; ih Lancet, 1833-34, vol. ii. quoted. TRACHEOTOMY. 119 was some degree of peculiar sonorous rale perceived on applying the ear to the chest at the point described as where the foreign body had become fixed. The operation was performed ; one pair of forceps opening laterally were introduced ; a hard sub- stance could be felt, but not grasped; the patient was re-assured, and allowed to recover the effects of the exploration and attempt to seize it. Another instrument with the blades differently arranged, was then passed down the tube, at least three or three and a half inches, and the bone immediately seized and extracted. * * * The result of the case was most satisfactory. The length of the forceps was seven inches, (pp. 415, 16.) The second operation was performed also successfully by Dickin, of Middleton, near Manchester, in 1832 (a), on a boy of eight years, who having "found a bell button, which he placed in his mouth, and during the act of jumping, it passed backwards into the windpipe. He instantly fell down, to all appearance in a state of suffocation, and was taken home, a few yards distant, making the most violent efforts to respire; after which his breathing became easy, but with repeated dispositions to cough, which alarmed him, threatening instant suffocation. * * * He complained of a sense of constriction across the chest, * * * had fits of coughing, which came on at intervals of two or three hours, during which he was comparatively easy. The face presented a purplish hue, with great anxiety depicted." Three days after, on examining the chest, its "appearance was most remarkable. On the right side a loss of symmetry, with evident depression and altered action in breathing. The stethescope indicated no respiratory murmur; whilst on the left side there was the plump symmetrical beauty of a youthful chest, with the common action of that side in respiration. * * * On the sixth day.the cough ceased, and also the fits of suffocation, which evidently indicated a fixed position of the foreign body." On the tenth day it was determined to perform laryngotomy between the cricoid and thyroid cartilages; which done, a pair of forceps invented for the purpose were introduced, and " acted as a sound, for on their introduction Dickin detected the presence of a metallic body. They were intro- duced again without the slightest inconvenience to the patient (at least apparently so,) when again the point came in contact with the button, which was laid hold of, and removed in their grasp. * * * For seyeral days a considerable quantity of muco-purulent matter was discharged through the wound, having accumulated around the button in the bronchus." (pp. 419, 20.) In a fortnight the boy was well, and returned to school. ' If, after opening the larynx or windpipe, the foreign body be jerked up into the wound, or shot through it, immediately after the free admission of the air, the wind- pipe be examined by passing a straight sound through it towards the chest, and no obstruction be found it will be right to examine the larynx itself, and the rima by passing a sound upwards into the throat. The necessity for doing this is seen from the case related by Pelletan (b), in which a person suffered severely from having a portion of tendon of veal lodged in his throat: it was so large that it was pre- sumed to have lodged in the oesophagus,• no relief, however, was obtained by the introduction of instruments, and Pelletan therefore opened the larynx by division of the thyroid cartilage, and on introducing his finger,, unawares thrust the tendon upwards, after which with the probang it was forced down the throat, and the patient recovered.—j. f. s. 1763. If bronchotomy be considered in reference to the three parts at which it may be performed, namely, on the thyroid cartilage, on the cri- co-thyroid ligament, and in the windpipe, the following circumstances must be borne in mind with reference to the special object of the ope- ration. In cutting through the thyroid cartilage, it may be feared, in addition to the possibility of it being ossified, and therefore difficult or incapable of being cut through, that the laryngeal ligaments may be wounded, and that in those cases in which the operation is undertaken, on account of a swollen and thickened condition of the inner membrane of the larynx, the air may not obtain a sufficient entrance ; the voice also may remain (o) Liston j just cited. (b) Clinique Chirurgicale, vol. i. p. 13. 120 RANULA. for a long while, or even permanently hoarse, if the operation be under- taken in the larynx. (Pelletan.) Tracheotomy, to wit, the cutting into the windpipe from the cricoid cartilage to the upper end of the breast-bone, is always dangerous; the cut always interferes with the anastomoses of the thyroideal arteries; if the arterial plexus of the thyroid gland be wounded, it is very difficult to stanch the bleeding, and the blood flowing into the windpipe causes violent cough. In thick-necked persons the operation maybe extreme- ly difficult, and even impossible. In children it is always very diffi- cult, on account of the thickness of their neck and the depth of their windpipe (1). If there be an arteria thyroidea ima, it will certainly be wounded. Opening the crico-thyroid ligament, and enlarging the wound down- wards through the cricoid cartilage, and the first two or three rings of the windpipe (LaryngOrtracheotomia) seems therefore to be the most advantageous proceeding, both where it is desired to assist the entrance of the air, and to remove a foreign body, because by this method the arterial plexus and the deep position of the windpipe are best avoided. Even if the foreign body be lower down in the windpipe, it may be either brought near the opening, by breathing or coughing, or it may be with proper care taken out with a blunt curved director or with the for- ceps. If it be found fixed in the larynx, the cut may even be extended from the crico-thyroid ligament along the middle of the thyroid cartilage. By this mode of proceeding, then, the object of the operation is best attained in all the conditions of the disease Which have been mentioned {par. 1756) ■ and a deeper cut into the windpipe would be required only in those cases where the situation of a foreign body in the oesopha- gus, or other tumours, which compress the windpipe may render it necessary. (1) According to Allan Burns (a), the position of the thyroid gland should he determined by the cricoid cartilage, and in children the space between this gland and the upper part of the breast-bone is great, therefore tracheotomy is easier. 1764. The varieties observed by Allan Burns in the vessels of the neck always renders careful observation necessary during the course of the operation. Be found the arteria innominata near the under edge of the thyroid cartilage, and even the carotid itself crossing the windpipe. Second Section.—OF UNNATURAL COLLECTIONS OF NATURAL PRODUCTS. A.—IN THEIR PROPER CAVITIES AND RECEPTACLES. I.—OF RANULA. Louis, Sur les Tumeurs Salivaires; in Mem. de l'Acad. de Chir., vol. iii. p. 462. Ibid., Sur les Tumeurs Sublinguals; in same vol. v. p. 420. Murray, De tumoribus salivalibus. Upsal, 1785. Breschet, Considerations sur la tumeur nominee Ranula ou Grenouillette; in Journal Univers. des Sc. Medic. 1817, vol. vii. p. 296. Reisinger, Bemerkungen iiber die Froschgeschwulst; in his Baier'schen An- nalen, vol. i. p. 1618. (a) Surgical Anatomy of the Head and Neck, p. 415. RANULA. 121 Kell, Beobachtnngen fiber Froschgeschwiilste; in von Graefe und von Wal- ther's Journal, vol. xxvi. p. 588. 1765. Ranula {Ranula, Lat ; Froschgeschwiilste, Germ. ; Grenouil- lette, Fr.) is a tumour beneath the tongue, sometimes soft and fluctuating, sometimes hard and firm, at first attended with little inconvenience, but in proportion as it enlarges, it interferes with chewing, and especially with speech. Should the swelling attain a very considerable size, it occupies the greater part of the mouth, thrusts the tongue upwards and backwards, occasionally also the front teeth outwards, and at the same time forms a swelling beneath the jaw. In this state the symptoms just described are very marked, the swelling itself becomes painful, and may inflame and suppurate. Ranula is sometimes developed not towards the mouth, but downwards, forming beneath the jaw and on the front and sides of the neck a very considerable swelling, which may be easily mistaken for an abscess. [The elder Cline used to mention in his Lectures that he was one morning alarmed by the noise of a person breathing with great difficulty in the next room to his consulting room, and on hastening in he found the man stretched on a chair, and almost suffocated. On being inquired of as to what was the matter, he pointed to his mouth; upon looking into which Cline observed a large ranula thrusting back the tongue, which he instantly punctured with a lancet, and relieved the patient from the threatening suffocation.—-j. f. s.] 1766. Passing over Pare's opinion of the nature of ranula, that it consisted of a cold, moist, clammy matter, which proceeded from the brain to the tongue, two different views have been taken of it. First, It has been considered as an encysted swelling by Fabr. ab Aquapen- dente, Dionis, Heister, Meckel, in part, von Winter, Syme, and others. Secondly, As a stoppage or closure of the Whartonian duct, from which results the retention of the spittle of the submaxillary gland and the distention of the walls of the duct in consequence of the spittle collected in it; an opinion first started by Munichs (a), afterwards more especially declared by Louis, and up to the present time held by most writers. This opinion rests specially upon the state of the fluid con- tained in the swelling, which, similar to white of egg in colour and con- sistence, by long continuance in the swelling, becomes viscid, dusky, and frequently mixed with stony concretions (1); and upon the possi- bility, in many instances, by opening the obstructed Whartonian duct with a probe, to discharge the fluid and effect the cure. Reisinger, who frequently found, by examination with a delicate probe, that the Whartonian duct was still pervious, supposes, on the contrary, that the thickening of the spittle was not merely the consequence of it being re- tained, and that this was always in proportion to the time the swelling had existed, but that unnaturally secreted spittle perhaps accompanied with atony of the duct, caused the development of ranula, and that it was not merely formed by the distended Whartonian duct, but that not unfrequently the distended Whartonian duct burst, and the secreted fluid poured out, and was contained in a sac of cellular tissue, not un- like a cystic tumour ; in which way the various forms of ranula, as well as the often occurring transparency of the Whartonian duct could be ac- counted for. This opinion has also been more recently put forth by (a) Praktyke der Heilkunde, p. 141. 11* 122 TREATMENT OF Hennemann {a). Kyll endeavoured to deny that ranula depends on distention of the duct; inasmuch as it is impossible, that so small and thin a duct could bear so great a distention as is observed in large swellings of this kind ; that the fluid contained is not at all similar to spittle, but of the consistence of fat oil, brownish, like yellow olive oil, clammy, clear, and transparent; and according to the statement of the patient after the operation, tasteless, and that these conditions are really from the first, and not as Louis supposes similar to the white of egg. When swelling has existed a longer time the submaxillary glands swell, inflame, and harden, by which their functions are destroyed. Lastly, If the spittle continue to flow, as after Dupuytren's mode of operating, the disease diminishes, at least it never increases, which, however, is not always the case. Upon these grounds Kyll holds to the old opi- nion ; according to him, the swelling has a sac which is probably an hydatid. [(1) The elder Cline himself had a stony concretion in one of the submaxillary ducts, which was readily removed by a slight cut through the membranes covering it. I am not aware, however, that it was accompanied with any degree of ra- nula.—j. v. s.] 1767. As unfortunately up to the present time pathologico-anatomical observations upon the seat of ranula are entirely wanting, it is impossi- ble to give a very decided judgment upon these different opinions, and still more as several swellings beneath the tongue are known, to which the term ranula has been applied, which have nothing in common with it but their seat beneath the tongue. In the entire absence of anatomical observations on the nature of this disease, chemical examination of the fluid can alone be useful in more satisfactorily deciding whether it be spittle or not. I have found this fluid, both in recent and long-continued ranula, pale yellow, or brownish yellow, clear, thickly fluid, like white of egg, very fibrous, so that it could not be poured in drops, but hangs together like mucus. Its chemical examination showed no resemblance to spittle ; it consisted principally of albumen. If, therefore, it be not admitted that the fluid which the submaxillary and sublingual glands secrete, differ from the spittle of the parotid gland in its composition; or if, when ranula exists, there be not an accompanying qualitative change in the secretion of these glands, then manifestly ranula must be considered as the collection of a peculiar fluid external to the Whar- tonian duct, beneath the mucous membrane of the mouth, or in a proper sac (mucous bag) which latter opinion I consider most likely, and there- fore ranula must be ranked with dropsy of mucous bags. According to the chemical examination of the fluid from a ranula of a boy of twelve years old, which my respected friend and colleague L. Gmelin has pub- lished, it consists of water 94-6, of soluble albumen with a very small quantity of stearine, osmazome, Salivary matter (?), and carbonate, nitrate and acetate of potash, 5-4, in 100 parts. Hence the fluid has no resemblance to spittle, as it wants the sulpho-cyanite of potash, and almost the entire salivary matter; on the other hand, it contains a large proportion of albumen, which does not exist in healthy spittle. Opposed to this is the examination by Dr. L. Posselt, of a stone weighing 0*623 of a grain, which I removed from the Whartonian duct, from which it appears that in 100 parts were contained 7*8 of matter soluble in water, which showed the re- action of salivary matter; 13-3 of matter insoluble in water (salivary mucus); 68-87 of phosphate of lime, and 9-93 of carbonate of lime. Poggiale found a stone from (a) Beitrftge Meklenberg. Aertze zur Med. und Chirurg., vol. i. RANULA. 123 the Whartonian duct to consist of 94f of neutral carbonate of lime, 4 per cent, of animal matter, and 2 per cent, of water. * » According to Fleischmann, there are a pair of mucous bags beneath the tongue, upon the m. geneo-glossi, where they enter the tongue, a little distant' from its front edge, in the fraenulum linguae, and behind the opening of Bartholin's duct. They are some lines in length, very distinct, and of unequal size on the two sides, the right being generally larger than the left. In one instance it was divided on the right side by a partition into two parts. When a salivary stone forms in Wharton's duct, inflammation and suppuration must arise in its gradual enlargement, by which the stone will be spontaneously thrown out,.as I have twice seen; but never, even when the duct is completely closed by the stone, is there any condition similar to ranula. There is inflammation and swelling of the glands, which if the abscess be discharged by bursting or cutting soon subsides, only a hardness in the surrounding cellular tissue remains for some time. 1768. According to the difference of opinion as the nature of ranula is the aetiology different. An altered condition of the spittle has been assumed by which it is disposed to the deposition of stony concretions, or simple thickening of the spittle, and thereby stoppage of the Whar- tonian duct is set up, or union of the duct by inflammation and the like. In no case have I been able to ascertain any decided causal condition. Ranula is not unfrequently observed in newly-born children, and occurs more frequently in early than in later years. 1769. The treatment of ranula consist either in opening the swelling and discharging its fluid, with which also it must be sought to prevent the complete closure of this opening, so that the ever-collecting fluid may have a continual escape ; or in putting a stop to the secretion by exciting a sufficiently smart inflammation, by destruction of the swelling with caustic, or by its removal with the knife. With these several ob- jects various modes of treatment have been proposed. First. Opening the swelling with the actuaLcautery, (Pare,) or with caustic, in persons who fear the knife with butyr of antimony (Zang.) Second. Puncture or cutting through its whole length (Louis.) Third. Cutting into the swelling and filling it with caustic and irritating materials, honey of roses with sulphuric acid, (Heister, Dionis,) lunar caustic, (Camper,) muri- atic acid, (Acrel,) stuffing with lint (Callisen, Schreger.) Fourth. Partially cutting away the external wall, (Boyer,) with cauterization of the hinder wall, (Sabatier, Vogel, Wilmer, Chopart, Desault, and others.) Fifth. Introduction of a seton (van der Haar and others.) Sixth. Introduction of a leaden thread, or of a bundle of lint (Louis, Sabatier.) Seventh. Extirpation of the whole sac (Marchetti, Richter, and others.) Eighth. Opening the swelling and in healing a little cylin- der of two flat small silver, gold, or platina plates, or a similar instrument of elastic gum. (Henning.) Richter (a) recommends, in the ranula of children, cauterization with lunar caustic. After a clean good wound has been produced by the first touching the whole surface, the caustic is to be repeated as often as the wound diminishes. This is never required more than ten times. When the ranula is not large and old, and its membranes are thin, the opening of the salivary duct sometimes appears like an aphthous spot, and is only closed with viscid matter or with a stony concretion; in such cases the duct should, according to Louis Chopart and Desault (6), be again rendered pervious1 by introducing a probe, and endeavouring to discharge the collected fluid, with which object the (a) Medicinische Vereinszeitung, 1838, No. 23. (b) (Euvres Chirurg., vol. ii. p. 217. 124 RETENTION OF BILE. passage of the canal must be endeavoured to be kept open, by introducing a leaden threas„ vol. ii. p. 382. (e) St. Thomases Hospital Reports, p. 26, RETENTION OF URINE, FROM STONE. 135 foreign body and the bladder, so as to prevent any retrograde movement of the former. This being secured, he again introduced the forceps into the urethra, and in the first attempt caught the piece of catheter, and drew it out." I am indebted to my friend Crisp, of Walworth, for the following two highly in- teresting cases, which were treated by him :— Case 1. An old sailor had been in the habit of passing the whole length of a tobacco-pipe into his urethra, for the relief of stricture, and on one occasion broke off a piece of it, which slipped into his bladder, and for which the usual operation for the stone was performed in Guy's Hospital, and he recovered. This accident, however, did not prevent him subsequently recurring to the same mode of treatment, when the pipe again broke, leaving about an inch and a half in the membranous part of the urethra. This he attempted to remove, by making a cut with a penknife into the perinaeum, as he lay before a glass, and succeeded in exposing the pipe, but being unprovided with instruments, and failing, by groping with his fingers, to get it, he was obliged to send for my friend, who drew it forwards with a pair of dressing forceps, and readily removed it. The man did well. Case 2. A man in Walworth workhouse, having made frequent attempts to commit suicide, at length, for the same object, passed a piece of stiff wire, about five or six inches long, into the urethra, as far as he could, and afterwards drove it with his fist under the arch of the pubes into the pelvis. By pressure on the perinaeum, the ex- tremity of the wire was indistinctly felt. A cut was made into the urethra behind the bulb, about an inch and a half in length, but the wire end not being seen, the cut was lengthened backwards about half an inch, which exposed the extremity of the wire. Much difficulty was found in seizing the wire, as at each attempt it re- ceded with the soft parts, when the points of the dissecting forceps (which only could be used, on account of want of space) were introduced; but when seized, it was readily withdrawn, and the man recovered. John Hunter says, that " bougies have been known to be forced out of the bladder along with the water, by the action of that: viscus and in several folds, (p. 134.) This is certainly a very rare occurrence, but by no means, impossible or im- probable; for there is a preparation in St. Thomas's Museum, of a large adventitious membrane, four or six inches long, and an inch and a half wide, which was voided by the urethra; and it is only necessary for the bougie to be so situated, as to form a sort of plug, against which the urine behind may be driven forwards.—j. f. s,] 1802. If a vesical stone lie against the neck of the bladder, and pro- duce ischury, the same proceeding as in inflammatory ischury, must be had recourse to, and the stone removed from the neck of the bladder, either by placing the patient on his back, with his pelvis raised, or by introducing a catheter. Lumps of blood and collections of mucus in the urethra are also relieved by passing the catheter. If small stones or other hard bodies stick in the urethra, itself, it must be attempted, by employing, at the same time, antiphlogistic and antispasmodic remedies, to squeeze them gradually out of the urethra, or with Hunter's or Cooper's forceps to withdraw them, after having carefully enlarged the passage by introducing thick bougies, especially of silkworm gut. If the object be not thus attained, a cut must be made, where the foreign body is situated, and thence it must be removed (1): a catheter is to be left in afterwards, and the edges of the wound tried to be healed with quick union (2). Retention of urine from small stones, which have got into the mouth of the urethra, or into its membranous part, is probably much more frequent, than generally supposed; in which case the diagnosis is doubtful, and if the catheter be introduced, the little stone cannot be felt, and the retention on the contrary, is to be considered inflammatory or spasmodic. As symptoms of such ischuria calculosa may be to a certain degree considered their occurrence after any mechanical movement, without other previous influence, and their cessation after such shaking. For the removal of these little stones, when the introduction of a catheter is not possible, for instance, when there are existing strictures, injections of water, made with some 136 FROM IMPREGNATED WOMB, ETC. force into the urethra, must be employed ; together with rubbing and shaking the perinaeum, but the bladder must not be previously overloaded, or the urethra con- siderably inflamed (a). [(1) If a stone or any other body be near the lips of the urethra, it may often be removed with a little dexterity and patience, by curving the eyed end of a probe, and gently insinuating it between the stone and the urethra, till the point be got behind it; then using the probe as a lever, it may be gently drawn forwards, and if when the stone reach the orifice of the canal, it will not pass, a small nick with a lancet at that part of the aperture, where it most clings, will soon allow it to come out. If the stone or body be in the membranous part, if the forceps fail in catching hold and pulling it out, a cut must be made directly down upon it. But in doing this it will be necessary to introduce the forefinger of the left hand into the rectum, so as to fix the stone and prevent it slipping or being pushed back into the bladder, in the attempt to seize it; for should that happen, it will be necessary at once to perform the usual operation for stone. (2) If the cut be made in the perinaeum, no catheter should be left in, but the wound allowed to heal, as after the operation for the stone. But if the urethra be opened before the scrotum, and specially if near to it, a catheter must be left in, to prevent the escape of the urine into the cellular tissue.—j. f. s.] 1803. In retention from the pressure of the impregnated womb, or other viscera, the palliative treatment consists in introducing the catheter: in the former case the ischury ceases after delivery; in the latter the hard- ening of the viscera must be got rid of, as well as other swellings which compress the urethra. Retention from retroversion of the worab has been already considered (par. 1308.) [I once operated for retention of urine in a case which, after death, was found to depend on a large cyst, containing an acephalous hydatid, which occupied the whole cavity of the pelvis, and lying between the bladder and the rectum, compressed the former between itself and the pubes, and as the bladder filled, it rose high/above the brim of the pelvis, in consequence of which, even after cutting into the perinaeum, the pressure was so complete that the urine would not escape, except on the introduction of a very long catheter, Which was continually displaced by the contraction of the bladder into the compressed part, into which no urine descended, and was only replaced with the greatest difficulty. The man died on the sixth day of constitu- tional irritation. Besides this cyst above mentioned, which contained 44 ounces of colourless fluid enclosed in the hydatid, there was another, about the size of a goose's egg, at the lower part of the sigmoid flexure of the colon, with thick walls, and an eschar upon it, where it had probably, at some time or other, burst. The bladder was empty between the lower and fore part of the large cyst and the arch of the pubes;, and between the cyst and the back of the fundus of the bladder were two or three small cysts of the size of small nuts, and upon the fore part of the fundus ano- ther as big as a swan's egg. All the cysts contained each an hydatid, except that on the rectum, on which there were several/—j. f. s.] 1804. Growths in the bladder, especially about its neck, are causes of ischury, and the diagnosis is always uncertain. Sometimes there is only one growth of much size, sometimes several: some have a thin stem, and others a broad base. The use of the catheter is the only palliative, Such growths when discovered in the operation for the stone, have been torn away with the forceps (6). 1805. Swellings of the prostate gland may arise in various ways, and the passage of the urine become difficult, or quite impossible. The swelling may depend on inflammation, varicosity of the vessels, harden- ing, and stone. 1806. Inflammation of the prostate gland may be consequence of (a) Schreger, Cliirnrgische Versuche, vol. i. p. 187.—Cloo.uet, I.: in Journ.de Mede- cine, vol. ii. p. 19. 1818. (6) Desault; above cited, p. 175. RETENTION OF URINE, FROM INFLAMMATION. 137 gonorrhoea, of external violence, and the like; in general, it developes itself quickly. The patient has a sense of weight and burning in the perineum and anus, a throbbing pain, the seat of which he refers to the neck of the bladder. The pain increases on pressure of the perineum, and specially on going to stool: the patient has difficulty and frequent urging to void his urine: the swelling of the prostate is felt on intro- ducing the finger into the rectum. In proportion to the degree of in- flammation, occur inflammatory symptoms and so on. If the inflammation do not disperse, it may pass on to suppuration. Under these circum- stances, after the inflammatory symptoms have gone over eight days, a throbbing pain is felt, increased fever towards evening, shiverings^ and symptoms of retention of urine, which subside a little, and increase afresh. The suppuration rarely appears to be seated in the proper sub- stance of the gland, but rather in its coverings, and in the cellular tissue, connecting the lobes of the gland ; frequently several groups of abscesses form, and in this case the patient generally sinks, some abscesses opening within, and others without, the abscesses burrow, and fistulous passages, and wasting suppuration ensue. ["As the abscess advances, the perinaeum becomes tender," says Brodie, "and there is a perceptible, though slight tumefaction and hardness in some one part of it. The abscess, if left to take its own course, sometimes bursts internally, that is, into the urethra; more frequently, it makes its way through the fascia, cellular membrane, and muscles of the perinaeum, and bursts through the external skin." (p. 144.) Brodie, however, mentions a fatal instance of abscess in the prostate, in which the patient, about thirty years of age, voided his urine every twenty or thirty minutes, complaining of an aching pain in the loins; but of no pain any where else. The urine deposited a small quantity of yellow puriform sediment. He said'that the symptoms had begun two years ago, and that in the commencement of the dis- ease, the urine had been tinged with blood. * * * About a month after his admission into the hospital, he was seized with symptoms of apoplexy, and died in the course of a few hours. * * * An abscess of the size of a large walnut occupied the posterior part of the prostate, and extended into the space between the bladder and vasa de- ferentia behind the neck of the bladder. * * * An irregular ulcerated Orifice was discovered.behind the verumontanum, through which the probe passed at once into the cavity of the abscess." (p. 146.)] 1807. The treatment of retention of urine from inflammation of the prostate, agrees precisely with that of inflammatory retention already de- scribed {par. 1795;) blood-letting, leeches about the anus, baths, soothing clysters, poultices to the perineum and the like. If the flow of urine be not thereby effected, the catheter must be introduced, which, however, can never be done without difficulty and great pain; because the swollen gland alters the direction of the urethra, on which account also a catheter with a long beak is required, and sometimes must have a large curve (1). If an abscess form in the prostate, the introduction of the catheter is the only remedy; the abscess is either opened by it, in doing which care must be taken not to make a false passage, or it bursts of itself and the pus escapes with the urine (2). The catheter must remain in the bladder till the urine be no longer mixed with pus. Desault {a) recommends cleansing injections of barley water at the same time. [(1) In reference to the enlargement of the prostate gland from acute inflamma- tion, Lawrence (6) says :—" You should avoid, if possible, the introduction of a catheter. There is a pretty actively inflamed substance against which, in its intro- (a) Above cited, p. 229. (6) Lectures in Lancet, 1829-30, vol. ii. 138 RETENTION OF URINE, duction, the point of the catheter will necessarily come, and through which it must pass in order to enter the bladder. The introduction of an instrument, under such circumstances, must be expected to aggravate the sufferings of the patient at the time; and therefore, if you can put a stop to the inflammation, and enable him to make water without the employment of an instrument at all, it will be very de- sirable for you so to do. Trust therefore, to antiphlogistic means, with which fomentations, the use of the hip or warm bath may he combined ; and do not have recourse to the use of an instrument, unless these means fail, and there should be an actual necessity for relieving the patient from the danger which the difficulty of eva- cuating the urine produces. If you come then to the introduction of an instrument, you should be aware of the particular change in the urethra, which the swelled state of the prostate produces. The swelled prostate does not diminish the dimensions of the urethra, but it alters the course and shape of the canal in that part which goes through the gland; it presses the sides of the urethra together, and the swelling of the prostate, the principal part of which is situated below the urethra, that is, be- tween the urethra and rectum, pushes the urethra up towards the pubes. At the same time, the enlargement of the prostate in size, an enlargement which takes place in all directions, increases the length of this part of the canal. The changes then pro- duced are, first, an elevation of the urethra, pushed upwards towards the pubes, an elongation of the canal in its prostatic portion, and a pressing together of the sides of it laterally. The best instrument in this case is a large elastic catheter; and, in- deed, I should observe to you, whether you employ an elastic or a silver catheter in cases of enlarged prostate, you will always find it necessary to use an instrument of full size, which will pass on much more easily than instruments of small size. The best instrument is, the catheter made of elastic gum, and you should use those which are made to retain their curved shape without a stilette. * * * If, however, you should fail in introducing such an instrument, you must have recourse to the silver catheter," and "the extremity of the instrument should be prolonged, so as to repre- sent more than a quarter of a circle; * * * a third or a quarter of an inch over that, so as to enable the end of the instrument to rise over the elevated part of the urethra." (p. 811.) Brodie advises:—"If there be a retention of urine, the gum catheter, without a wire or stilette, may, in almost every case, be readily passed into the bladder. It is better to use a very small catheter, and to introduce it again, whenever it be neces- sary to do so, than to leave it constantly in the urethra and bladder." (p. 145.) As to the size of the catheter in enlarged prostate, under any circumstances I must con- fess I prefer the larger, as recommended by Lawrence, for the reasons he has assigned, which have been verified by my own experience; and a silver to an elastic catheter, on account of its greater firmness, which prevents mischief.—j. f. s.] (2) "If there be reason to believe," observes Brodik, "that abscess is formed, you should endeavour to procure an external discharge for the matter, in order to prevent it bursting into the urethra. If the symptoms described exist, and go on for some time increasing, and you discover a fulness and tenderness of theperinxum, do not wait for any more certain indication of abscess; but introduce a lancet in the direction indicated by the tenderness and swelling. It will often be necessary to pass it quite up to the shoulders, or even to the handle, before you reach the abscess. But you may do this fearlessly. There is no danger from any ill consequence from such a puncture. If there be abscess, you will, by this proceeding, immediately relieve the distress which the patient suffers, at the same time that you prevent fur- ther mischief. If, on the other hand, there be no abscess, the puncture does not make the condition of the patient worse than it was before. Indeed, partly from the loss of blood, partly by removing the tension of the soft parts of the perinaeum. it is generally useful to the patient, even when it does not answer the purpose of allow- ing the escape of matter." (p. 146.)] 1808. Swelling of the prostate gland from vancosity of its vessels occurs in general, slowly, in old persons after previous haemorrhoidal ailments, in stoppage of the bowels, after venereal debaucheries, after repeated claps, with sedentary living and good living, after abuse of heat- ing drinks, after frequent efforts in voiding the urine and going to stool. It is always developed slowly. Emptying the bladder becomes more FROM VARICOSITY OF THE PROSTATE. 139 difficult after violent exertion, after heating food and drink and the like. The swollen prostate is felt on introducing the finger into the rectum, but is free from pain, and the patient suffers no pain in the passage of the urine through the urethra. The varicosity is situated rather in the cover- ings of the prostate ; the substance of the gland itself is therewith some- times soft and spongy, sometimes tense and hard. 1809. If this disease have any distinct cause, it must be removed. In general, taking away blood from the perineum, clysters of cold water or decoction of oak bark with alum, are sufficient. The introduction of the catheter is in this case always difficult, and the circumstances above mentioned {par. 1807) should be always borne in mind. Sometimes a swollen vessel is torn in passing the catheter, in consequence of which bleeding occurs, which gives relief. The inlying of a catheter is here necessary for the purpose of compressing the swollen vessels, and by its accompanying irritation to excite their contractile activity. The treat- ment is always tedious, and no cure is to be expected under six or eight weeks. 1810. Hardening is the most common diseased change to which the prostate gland is subject. It occurs after previous slow inflammation, most commonly after forty years of age, and earlier if the urethra be affected, especially in scrofulous subjects and in those who when young have indulged in venery; after repressed eruptions on the skin, and as the consequence of gout and the like (1). It always proceeds slowly; voidanCe of the urine becomes difficult, and is sometimes completely stopped. The prostatic humour is sometimes exceedingly copious and viscid. The direction of the urethra is changed according as the right, left or middle lobe of the gland is swollen. The hardened prostate is felt by examination through the rectum; the patient has difficulty in going to stool; a discharge of mucus-like fluid, an unusual sensation about the rectum after going to stool, as if the bowel were not completely- relieved. All the symptoms described {par. 1675) as belonging to stric- ture, frequently accompany swelling of the prostate (2). In reference to the secretion of a mucus- or pus-like fluid which may accompany the various diseased conditions of the urinary passages, it may be remarked that the more mucus-like, thick, pus-like deposit which the urine throws down, and which remains loose at the bottom of the chamber-pot, shows a catarrhal inflammation of the mucous membrane of the bladder; the mucus-like deposit which draws out in threads, is elastic like white of egg, and sticks to the bottom of the pot, characterizes disease of the prostate; purulent deposit, and the prostate gland small, soft and flat- tened mark its destruction by suppuration. If on examination the prostate be unin- jured, the pus comes probably from the kidneys (a). The mucus from the prostate is not ammoniacal; the mucus from the bladder rarely appears in any great quantity without containing some earthy parts. [(1) " Chronic inflammation of the prostate gland is," says Astley Cooper (o), "the consequence of age, and not of disease. When this disease produces partial retention of urine it should be considered as a salutary process, for it prevents incon- tinence of urine, which, in old people, would almost constantly take place were it not for this preventive. It makes the urine pass slower than natural, but this may be excused when it is the means of preventing a continual wetting of the clothes." (p. 239.) Brodie observes:—"When the hair becomes gray and scanty, when specks of earthy matter begin to be deposited in the tunics of the arteries, and when a white zone is formed at the margin of the cornea, at this same period the prostate usually, (a) Lallemand ; above cited, p. 152. (6) Lectures in Lancet, 1823, 24, vol. ii. 140 RETENTION OF URINE. I might perhaps say invariably, becomes increased in size. This change in the condition of the prostate takes place slowly, and at first imperceptibly, and the term chronic enlargement is not improperly employed to distinguish it from the inflamma- tory attacks to which the prostate is liable in early lite. (p. 151.) The chronic enlargement of the prostate may be said to be a disease of a peculiar kind, having no exact resemblance to what we meet with in any other organ. It may, however, in some respects be compared to the chronic enlargement of the thyroid gland, known by the name of bronchocele. Like the latter, it is generally slow in its progress, and frequently, after having reached a certain point, if proper treatment be employed, it remains almost stationary for many years. It is, on the whole, a rare occurrence for it to terminate in ulceration or abscess, and the symptoms to which it gives rise, are, with a few exceptions, to be referred to the influence which the disease exer- cises over the functions of the parts in the neighbourhood." (p. 154.) . Although enlarged prostate is especially the disease of advanced life, yet Astley Cooper says he has "known it occasionally occur in very young people. An in- stance of this kind happened in Guy's Hospital: a boy was admitted having symp- toms of stone, in consequence of which he was sounded, and the operation of litho- tomy was about to be performed; the sounding, however, brought on inflammation of the bladder, which terminated in the boy's death. Upon dissection it was found that the symptoms for which he had been sounded were produced by. an enlarged prostate." (p. 245.) "I have certainly seen a very few cases of it," (enlarged prostate,) says Law- rence, "in young persons, but the great majority of those you have to treat for this complaint are past the middle period of life." (p. 813.) The part of the prostate gland in general considered as specially enlarged is that which John Hunter describes as that " small portion of it which lies behind the very beginning of the urethra, swells forwards like a point into the bladder, acting like a valve to the mouth of the urethra, which can be seen even when the swelling is not considerable, by looking upon the mouth of the urethra from the cavity of the blad- der in a dead body. It sometimes increases so much as to form a tumour (of which Hunter gives two engravings^ V. and VII.) projecting into the bladder some inches." (p. 188.) It is this same part which EverardHome has dignified with the name of third lobe of the prostate, and claimed the discovery of, without adding any thing to what Hunter had said about it, except that of the five cases he examined, and on which he grounded his claim, " the appearance," he says, " was not exactly the same in any two of them." (p. 10.) And yet this has got the name of Home's third lobe, and is so continually called in spite of John Hunter's observation, and the knowledge that the French anatomists have long since been well aware of it under the name trigone. In reality, however, so far as I have had an opportunity of observing, the two principal or side portions of the gland are most commonly en- larged at the same time and in the same proportion as this small portion which lies behind.—j. f. s. " The next thing noticed is," says Astley Cooper, " that the urine has a particu- larly powerful smell, which arises from its being ammoniated in consequence of some urine remaining in the bladder after each discharge. * * * The next symptoms are pain and numbness in the glans penis; sense of weight and uneasiness in the perinaeum, relieved by pressure with the finger; pain in the back of one or both thighs, in the loins, and at the origin of the sciatic nerves, and in the course of the ureters; the faeces are flattened, from the pressure made upon the rectum by the swollen gland. Persons having enlarged prostate for any length of time, generally have, likewise, prolapsus ani and haemorrhoids. * * * The ammoniacal smell of the urine as the disease advances, becomes highly offensive, and at length the urine itself becomes white or milky; this appearance shows that the inflammation has extended to the mucous membrane of the bladder. If the urine be much retained, it has the appear- ance of coffee, occasioned by an admixture of blood with it; this leads many prac- titioners to suppose, for the moment, that the case is one of stone; but if you ques- tion the patient for a few moments, your doubts on this point will be removed." (p. 240.) "Upon dissection," continues Astley Cooper, "the prostate is found enlarged sometimes laterally ; but most frequently the enlargement is in ihe posterior part, situated in the middle or third lobe. As the prostate enlarges it is pushed forwards, FROM CHRONIC ENLARGEMENT OF THE PROSTATE. 141 in consequence of which the urethra becomes curved immediately before the apex of the prostate; indeed, the coming forward of the prostate causes the urethra almost to double upon itself. The curve thus formed is at the symphysis pubis; and it is in this situation that the difficulty on passing the catheter in diseased prostate is found. Tracing on the course of the urethra, behind the curved part, that canal is seen much enlarged, and the urethra itself is considerably elongated, that is, from an inch and a half to two inches ; which increase of length is behind the pubes, and it is owing to this circumstance that you are under the necessity of carrying on the catheter so great a distance after its point has passed the arch of the pubes. As to the prostate itself, we find that it may increase to a most enormous size laterally, without giving rise to retention of urine; but that enlargement which occurs posteriorly in the third lobe, frequently occasions retention of urine, for the enlargement is situated imme- diately behind the orifice of the urethra; thus the urine collecting behind the swell- ing presses it against the mouth of the urethra, and forms a complete barrier to its passage." (pp. "ill, 42.) "This tumour," (of the third lobe,) observes Brodie, "varies in size from that of a horse bean to that of an orange. When small, it is of a conical form, with the apex of the cone projecting into the bladder, and the basis being continued into the rest of the prostate. When large, the basis is often the narrowest part, and it swells out so as to have a pyriform figure towards the bladder. In some instances, by the side of that which I have just mentioned, there is another tumour, formed by one of the lateral portions, also projecting into the bladder. The canal of the urethra, where it passes through the enlarged prostate, is generally flattened ; and when the latter is divided transversely, the urethra appears like a slit, rather than like a cylin- drical canal. Not unfrequently the enlargement of the prostate so alters the form of the urethra, that, instead of pursuing a straight course through the gland, it is in- clined first to one side and then to the other. You would expect the urethra to be narrow, in consequence of the increased bulk of the parts by which it is surrounded ; and o it is in many instances; in others, however, it is actually wider, being dilated into a kind of sinus, where it lies in the centre of the prostate. I have known such a sinus to contain two or three ounces of fluid." (pp. 152, 53.) (2) Astley Cooper asks:—" How, when diseased prostate exists, are you to know if? What are the diagnostic signs'? Why, the enlargement laterally may be readily ascertained by introducing the finger into the rectum ; but the enlarge- ment of the middle lobe cannot be so learnt. In what way then 1 Why, by the introduction of a catheter or bougie, and the latter is best; it will be found to stop suddenly; you are then to introduce a catheter for the purpose of drawing off the water; the instrument will be resisted in its common course, and you must depress the handle a good deal, with a view of tilting its point over the enlarged gland; thus the end of the instrument will be rising perpendicularly, as it were, behind the pubes. These, then, are the means you are to employ to obtain a correct diagnosis." (pp. 242, 43.) "The symptoms of retention of urine from enlargement of the prostate, are not very different from those which occur where the retention is the consequence of stric- ture, but the termination is different. I never saw," says Brodie, "a case in which, under these circumstances, the bladder had given way, as sometimes happens, where there is a retention from stricture; but I am informed that such a case has occurred, and that the bladder ruptured at its fundus is preserved in the Museum of St. Bartholemew's Hospital." (p. 155.) 1811. The prognosis in this disease is always unfavourable. Only in the beginning is there hope of being able to disperse the hardening; in advanced cases, the distease may sometimes be diminished, and the pa- tient's condition may be rendered tolerable by the inlying of the catheter. At the first a corresponding antiphlogistic treatment must be employed ; afterwards issues and blisters to the perineum, rubbing in volatile lini- ments with camphor, mercurial ointment, iodine salve, suppositories of cicuta and opium; internally, cicuta, mercury, decoction of daphne meze- reon, uva ursi, and the like, but especially hydrochlorate of ammonia in Vol. iii.—13 142 TREATMENT OF RETENTION OF URINE increasing doses (a). If the hardening have a definite cause, the cura- tive means must be directed to it. In introducing the catheter, the points already mentioned (par. 1807) must be considered. If an elastic cathe- ter be left in, it does not retain its proper curve after the removal of the stilette, and the urine escapes; it is better, therefore, to use those elastic catheters, which have a permanent curve. [As to the treatment of enlarged prostate, Astley Cooper says:—"Very little can be effected here by medicine; it is a disease over which medicines have but very little influence. You may, however, give the oxymuriate of mercury in very small quantities, for I believe I have seen it beneficial. But this is the treatment only for the enlargement of the gland. * ..* * When no urine whatever can be passed, and when there is great pain at the neck of the bladder," he recommends to "take blood from the arm, apply leeches to the perinaeum, administer purgatives, and put the patient in a warm bath. If these means should succeed in procuring relief, the best medicine that can afterwards be given for the purpose of preventing a return of the retention, and at the same time oflessening the inconvenience which sometimes attends the complaint, is composed of fifteen drops of the liquorpotaseat, five drops of bals. copaib., and an ounce and a half of mist, camph. If you give fif- teen or twenty drops of the balsam it then produces a stimulating effect, and does harm; administer it in the quantity just mentioned, in conjunction with the other medicines, to which may be added two drams of muc. gum. acac. * * * Other medicines,, as the carbonates of soda and magnesia, the liquor potass., with o/»'wm, are occasionally given, but as the latter produces costiveness it is improper. The first medicine will be found the best; it will afford considerable relief, which is all that you can expect, for you must not dream of making a cure." (pp. 243, 44.) Lawrence says :—" In the case of this chronic enlargement of the prostate, we have not much powex of relieving the patient by producing any great redaction of the affected part. * * * By attention, however, to diet, careful attention to the state of the stomach and bowels, by a course of mild alterative and aperient medi- cines, we can keep the patient perhaps in a tolerable healthy state. Attempts have been made sometimes to reduce this enlargement by seton or issue on the perinaeum or upper part of the thigh, but it is an inconvenient course of proceeding, and one to which patients are not inclined to submit." (p. 813.) " When from any cause the vessels of the prostate are more than usually turgid with blood," says Brodie, "the quantity may be diminished, and thus a reduction of size, to a certain extent, may be effected. It is with this view that we recom- mend topical blood-letting, the exhibition of gentle purgatives, a moderate diet, and, above all, perfect rest in the horizontal posture. But we are not acquainted with any method of treatment which is capable of restoring the gland to its original con- dition." (p. 17:3.) "The treatment of retention of urine from diseased prostate," observes Brodie, " is one of the most important subjects in Surgery. The patient suffers miserably; his life is at stake ; he lives or dies according to the skill which you are able to exercise in his favour. The case is altogether different from one of retention of urine from stricture. Bougies are of no service: even if you pass one into the bladder, no urine follows; the parts collapse and close as the bougie is with- drawn." (p. 174.) Astley Cooper lays down that when "called upon to relieve retention from en- larged prostate, by the introduction of a catheter, the instrument should be fourteen inches in length, and a quarter of ah inch in diameter. In consequence of the pressure within, a broad instrument will answer better than a narrow one, for being bulbous at the end it will readily ride over the enlargement. When introducing the catheter, you will meet with no difficulty until you Teach the curve which the en- largement of the gland has produced in the urethra ; the handle of the instrument is to be here slightly raised, for the purpose of insinuating the point through the curved part. Having passed this you are then to depress the handle completely between the thighs, so as to occasion the point of the instrument immediately to rise perpen- (a) Fischer ; in Rust's Magazin, vol. xi. Practical Observations on tl^e Diseases of p. 2d4.—Cramer; in Hufeland's Journal, the P rostate Gland, vol. i. London, 1811; 1824, p. 35.—See also Home, Everard; vol. ii. 1818 bvc FROM CHRONIC ENLARGEMENT OF THE PROSTATE. 143 dieularly above the pubes. * * * This will cause the point to enter the bladder between the pubes and enlarged lobe. * * * "If it be deemed requisite to leave the catheter in the bladder, I should prefer," says Cooper, "one of peWter rather than elastic gum, for it can be curved downkbefore the scrotum, and by plugging up the end, the patient may move about as he likes, and at any time he wishes can expel his urine. * * * The pewter catheter should be quite new, and ought not to be worn for a longer period than a fortnight, for the urine acts upon the metal, renders it brittle, and may probably cause the instrument to snap, if the time be extended beyond what I have stated. If there be need of puncturing the bladder for enlarged prostate, it must be done above the^uoes,- but it never need be attempted at all if you can perform your duty." (pp. 243, 45.) " In instances where the bladder does not evacuate its contents completely, where there is a constant accumulation of urine within it, the course you have to pursue," says Lawrence, " is to introduce the catheter regularly once or twice in the four- and-twenty hours, so as to draw off the stale urine, and to give the bladder the opportunity of recovering its power of contraction; and after following this up for some, time, perhaps two or three weeks, you generally find that the evil is removed, and that the patient recovers the power of completely emptying the bladder. * * * It is necessary that the catheter should be longer than that which is employed under ordinary circumstances; give it the length perhaps, of fourteen inches, curved as already stated, and always use a catheter of full size. * * * In such cases where the smallest catheter could not be introduced, I have repeatedly succeeded in intro- ducing an instrument of this size with the greatest ease." (p. 8V4.) Brodie " rarely uses any but a gum catheter. It gives you rather more trouble to learn the use of the gum catheter, and to become dexterous in the management of it, than it does to learn the use of the silver catheter. When, however, you have once become familiar with the gum catheter, you will generally prefer it to the other; and there is always this advantage in it, that when you have succeeded in intro- ducing it into the bladder, it may, if necessary, be allowed to remain there. A gum catheter may be. retained in the urethra and bladder with very little incon- venience to the patient, which is not the case with a silver catheter." (p. 175.) Brodie uses, as did Home, the gum catheter without a wire, as a flexible, or with a wire as an inflexible instrument; and directs that it should not be mounted on a small flexible straight wire, but on a strong iron stilette, having the curve of a silver catheter. l!e begins with passing a gum catheter without a stilette; if it will enter the bladder, so much the better; it gives no pain, does not lacerate the urethra, nor produce hemorrhage; it may do all that is required, it can do no harm, even in a rough hand ; failure will notrender it more difficult to pass another instrument. In difficult cases indeed it will not succeed, and then the catheter with the iron stilette must be used. " You ought not to use a catheter so large as to give pain ; but for the most part you will find one which is large enough to fill the urethra, without stretching it, to be more easy of introduction than a smaller one, which approaches to a pointed instrument, and the extremity of it is liable to become entangled in the tumor of the prostate. The stilette ought to be considerably curved ; the reason of this is obvious, (p. 176.) Always bear in mind, in introducing the catheter, that it is to be used with a light hand. It should be held, as it were, loosely with the fingers. It will then, in great measure, find its own way in that direction in which there is the least resistance. If you grasp it firmly, it can only go where you direct it, and it is likely to puncture and lacerate the membrane of the urethra, and the substance of the prostate, and to make a false passage instead of entering the blad- der. [Most excellent directions and cannot be too closely followed.—j. v. s.] I generally find," continues Brodie, "that I introduce the catheter best by keeping the handle of it close to the left groin of the patient. I pass it as far as possible in this position; then I bring the handle forwards, nearly at a right angle to the pubes, and not elevating it towards the navel. The next thing is to depress the handle, which is to be done gently and slowly, by placing a single finger on it, and press- ing it downwards towards the space between the thighs. In depressing the handle, you generally find the point of the catheter slide into the bladder. Sometimes, however, this does not happen until you withdraw the stilette; and in the act of doing this, the introduction of the catheter is completed." (p. 177.) " I do not mean to lay it down absolutely as a rule, that you should allow the catheter to remain, but I am certain that it is prudent to do so in the great majority of cases. If you, 144 TREATMENT OF RETENTION OF URINE remove it, so abundant is the flow of urine which immediately takes place from the kidneys, that you will find the bladder again loaded, and requiring the re-introduc- tion of the catheter within five or six, perhaps even within three or four hours. It will be necessary to use the catheter again after another short interval, and it will often happen, when there has been no difficulty in the first introduction of it, that there is considerable difficulty afterwards. You avoid all this by leaving the catheter in the bladder ; and there is another advantage in this mode of proceeding. The prostate is kept in a state of more complete repose, and in one much more favourable to recovery, so far as recovery can take place, that it would be in, if irritated by repeated introductions of the instrument." (p. 180.) " You will very rarely fail, by dexterous management, to introduce the catheter, but you may fail, nevertheless, in some instances. What is to be done under these circumstances 1 * * * You may puncture the bladder above the pubes, or you may proceed thus: When all your efforts to introduce the catheter have been unavailing; when you feel the point pressing against the tumour of the prostate, and unable to pass over it, apply some force to the instrument at the same time that you depress the handle. It will generally penetrate through the prostate, enter the bladder by an artificial opening, and relieve the patient; and, x)f course, will continue to relieve him, if you allow it to remain ir. the bladder. This mode of proceeding has been strongly recommended by some very good surgeons, and I am not aware that it is attended with danger, although it may not be without its disadvantages. There is reason to believe, that in some cases in which this has been done, the natural orifice of the urethra has become so closed, that the patient could never void a drop of urine by his own efforts, being compelled to rely wholly on the catheter ever after. Sir Everard Home has published the history of a case of that kind, which was attended by Mr. Hunter and himself." (pp. 181, 82.) With regard to the question of introducing the catheter twice or thrice a day, or, after having introduced it, to leave it there, I must confess I prefer the former, and the use of a large silver catheter; occasionally, it is true, there is some difficulty; but, in general, so far as my experience has proved, the catheter, after having been passed a few times, enters the bladder as readily as a sword into its sheath. On the other hand, I have found that leaving the catheter in for a time, is liable to render the bladder irritable ; and that if at the end of a week or ten days, it be with- drawn, it is almost invariably found encrusted, more or less, with calcareous matter, which often renders its withdrawal difficult, and generally causes much pain, if not further mischief, by its roughness.—j. f. s.] 1812. If in strictures of ihe urethra, complete retention be produced either by the use of heating drinks or other excess, or by the progress of the disease itself, the most proper treatment is to introduce a fine wax bougie, which when its point has got into the opening of the stricture, is there held, as is distinctly shown in the vain attempts to draw it back. So soon as it will not move on without using violence, it must not be forced further, but allowed to remain, till a violent disposition to make water come on, when it must be withdrawn, and the urine generally flows out in a thin stream. Some persons immediately introduce a bougie, which generally passes further, and may remain till the urging to void the urine comes on. At the same time, according to circumstances, may be employed blood-letting, leeches to the anus and perineum, baths, sooth- ing clysters, with opium and the like. After repeated introduction of the bougie, in general a thin elastic catheter may be passed into the bladder. If by these means the danger of the retention be removed, then the treatment of the stricture must be commenced according to the former rules. Amussat (a) recommends the employment of forcing injections in cases of reten- (a) Archives Generals de Medecine, vol. ix. p. 294, 1825.—Magendie; Journal de Physiologie, vol. vi. p. 97. 1826. FROM THE STRICTURE OF THE URETHRA. 145 tion of urine dependent on stricture. He introduces a flexible catheter, without a beak, down to the obstruction, compresses the penis, and screws on to the end of the catheter a gum-elastic bottle, by which fluid can be injected and drawn out again. Lallemand and Begin (a) think it must not be forgotten that forced injections may be useful, if employed with moderation and prudence, and after the use of antiphlo- gistics and attempts to introduce bougies have been fruitless; but that in such case care must be taken not to use too great violence, for if a plug of mucus be the only or principal cause of retention, it will give way without any violent efforts, and if the parts be dilated by separating them, the power exercised in their contraction being equally on all parts of the urethra, which the fluid fills, it will produce severe pain and increase the inflammation; or what is worse, may find some part of the canal which is more friable and weak, and tear it. [The treatment which a stricture producing retention of urine will admit of, de- pends principally on the degree of distention of the bladder, and the irritability of the patient. Attempts should always be made to introduce the catheter both before and after drawing blood quickly from the arm, and placing the patient in a warm bath, so as to induce faintness. The catheter should be used with great care" and tenderness, to avoid the formation of false passages, which are too frequently made in striving to pass an instrument on these occasions. If the catheter cannot be got in, and the symptoms be urgent, it will be advisable to open the urethra from the perinaeum, and if there be a stricture, to cut through it, so that the cure of the wound and of the stricture may go on together. It is better to resort to this practice early, if the retention be complete, rather than to wait till the urethra burst behind the stricture, and extravasation of urine take place; as by so doing the wound heals nearly as after the operation for stone, without much difficulty, and the patient is saved from the trouble and danger of sloughing of the cellular tissue and urinary abscesses. If, on the contrary, the symptoms be not urgent, and the retention have not existed many hours, it is advisable to give tincture of muriated iron in sufficient quantity to produce nausea, by which sometimes, the spasm, which almost inva- riably accompanies a stricture with retention, is relieved, and the patient passes his water. Purging also of watery stools is also very often efficient in relieving reten- tion, for which purpose a couple of drachms of sulphate of magnesia, with fifteen or twenty drops of tartarized antimonial wine, with mint water, may be given every two or three hours, till the medicine operate freely, and then, generally, the water begins to pass. Cutting into the urethra, however, should never be deferred when the retention is not, after a few hours, relieved, either by these means, or by the catheter.—j. f. s.] 1813. If by these means no evacuation of the urine can be obtained, and the symptoms become urgent, then puncture of the bladder is re- quired. For this purpose, several writers have recommended breaking through the stricture, that is, with a silver conical pointed catheter to penetrate forcibly through the stricture into the bladder, to allow it to remain there several days, and then alter a certain time to introduce an elastic catheter for the purpose of keeping open the canal of the.urethra. This proceeding, which is especially founded on Desault's observations and particularly defended by Boyer, is unquestionably, even in the ablest hands, most highly dangerous, as tearing the urethra, false passages, perforation of the bladder, severe pain and inflammatory symptoms so easily follow it. The firmer the stricture and the greater its extension, the earlier are these consequences to be dreaded. Only in strictures of slight extent, which have not been thickened and increased by frequently repeated inflammation from previous attempts with bougies or caustic, does this method seem applicable. Even in these cases, the use of a conical, pointed sound, will easily produce the above-mentioned symp- toms, and the use of a thick sound with a rounded end, as proposed by Mayor, is still the most preferable, as being accompanied with much (a) Dtctionnaire de Medecine et de Chirurgie pratiques,, vol. xiv. p. 341. 13* 146 CUTTING INTO THE PERINEUM. less danger of forming false passages and tearing the urethra. Under all other circumstances, if the symptoms be pressing, puncture of the blad- der deserves undoubted preference. Upon breaking through the stricture, the following may be compared :—Desault, above cited, p. 244.—Roux, Relation d'un Voyage fait a. Londres, etc., p. 314. 1815.—Boyer, Traite des Maladies Chirurgicales, vol. ix. p. 232.—Cross, Sketches of the Medical Schools of Paris.—Charles Bell, above cited, p. 148.—Ducamp, above cited, p. 79.—Mayor, Sur le Catheterisme simple et force, etc. Paris, 1836. Second Edition.—A. Vidal de Cassis, Lettre chirurgicale k M. Mayor. Paris, 1836.—Mayor, Sur le Catheterisme, en reponse k une Lettre chirurgicale de M. Vidal. Paris et Geneve, 1836.—Principes fondamentaux du Catheterisme; in Ga- zette Medicale, vol. vii. p. 353. 1839. Of Cutting into the Urethra in the Perineum. In retention of urine caused by stricture Eckstrqm (a) has proposed a less dan- gerous method of effecting puncture of the bladder, and has pursued it with happy results.. After the patient has been placed as in the operation for the stone, a gum- elastic catheter is carried down to the stricture, and held firmly by an assistant, who at the same time, when the stricture is behind the scrotum, as is usually the case, lifts the scrotum up and stretches the skin of the perinaeum. The surgeon, with a pointed bistoury, then makes, nearly the length of the raphe, and in the direction given by the sound, a cut an inch and a half long through the skin, lays bare the urethra, that the course of the sound and its extremity can be traced. The patient is then desired to strain for the purpose of making water, by doing which, the urethra behind the stricture is. distended and hard, a eut is now made into the urethra to- wards the sound, and the opening thus produced is enlarged to and through the stricture and sometimes, behind it. The point of the fore-finger of the left hand must never for a moment during this operation leave the point of the knife, but must serve as a director. The urine now springs out with violence, and the bladder is emptied; but if this do not readily happen, on account of the palsy of the organ from disten- tion, a female catheter must be introduced into the wound, by the aid of which, the tapping is effected. If no severe symptoms of inflammation or irritation exist, which, however, is very commonly the case, a common silver catheter No. 6 is to be intro- duced into the bladder. W'hen its extremity reaches the wound, that is, the spot where the stricture was, it must be continued deeper, the finger in the wound giving it the proper direction, so that it may not slip from the urethra, but go directly into the bladder. When this has been once effected, and the instrument has been left in the bladder two to four hours, there is no fear of the least difficulty in its re-in- troduction, and a flexible catheter of the same size may be used instead of the former, the wound is bound up with lint, or a compress, dipped in cold water, applied, and it usually heals quickly. For the purpose of getting rid of the existing stricture, catheters of large size must soon be resorted to, but there must not be too much haste,-especially before the wound has healed. On the other hand, should there be inflammatory symptoms present, the introduction of the catheter must be stayed, in order not to increase the irritation. The wound in the perinaeum keeps open by the escape of the urine, and suppurates more or less. Afterwards, the above treatment must be employed (1). Jameson's (b) treatment also resembles.this. Lallemand and Begin (c) object to this operation the difficulty of finding with certainty and cutting through the urethra behind the bulb, especially in fat persons; and the uncertainty of the true condition of the canal of tbe urethra, and of the point behind which it must be opened. • [(1) I leave Eckstrom's description of the mode of cutting into the perinaeum for retention of urine*just as Chelius lias given it, for it cannot be better described, but (a) Froriep's Notizen, vol xvii. p. 155. xii. p. 329.—Leger ; Dissert, de Paracentesi 827. Urethras in Ischuria Perinasi. Paris, 1778. (6) Medical Recorder, vol. vii. p. 25y vol., (c) Above cited, p. 347. INTRODUCTION OF THE CATHETER. 147 I must deprive him of the credit of having proposed this mode of treatment. To my own knowledge, it has been for more than thirty years the common practice, excepting that a silver instead of an elastic catheter is first introduced down to the stricture as a guide, in St. Thomas's and Guy's Hospitals, and among the surgeons brought up in those schools. In the many months which Eckstrom spent with us some twenty-five years since, he must have seen this very operation performed again and again in the precise way in which he describes it; and it was then so old, that no one, that I am aware, laid any particular claim to the discovery of it. He must not, therefore, run away with the credit of having proposed not only the best, but the only operation for retention of urine which ought to be performed, with the single exception of retention from enlarged prostate, in which, if an operation for retention be ever required, that above the pubes must be performed.—j. f. s.] Of the Catheter and its Introduction. 1814. The catheter is a cylindrical tube of different thickness, straight- ness and curve, corresponding to the extent and curve of the urethra. It may be either firm or flexible ; in the former case it is best to be made of silver, and in the latter, of elastic gum or caoutchouc. The* length of the catheter is different; for adult women six, and for young females five inches is sufficient; for adult men from ten to eleven, and the seve- ral periods of boyhood from five to seven inches. The thickness also varies ; for women two lines, for girls a line and a half, for men two and a half lines, and for younger males a line and a half. The front third of a small catheter is slightly curved, and corresponds to the segment of a circle of which the diameter is six inches.(l); the other parts of the catheter are straight, and its upper end is provided with a ring on each side. The female catheter is only slightly curved at its front extremity. The front end of the instrument is rounded, and has on either side a pretty large and well rounded hole. The walls of the catheter should not be very thin, and its surface should be well smoothed and polished (2). AH catheters should be furnished with a stilette fitting into their cavity, and in elastic catheters it is best that this should be made of iron. A large catheter is in general more easy of introduction than a small one, because it properly distends the walls of the urethra, and is not so easily caught in its folds as a smaller one. In cases, however, where considerable obstruction has to be over- come, as in stricture, a small catheter is passed more easily. One oval opening on the side of the front end of the instrument is better than several smaller ones, or than two on opposite sides ; the little holes being easily stopped up in the former, whilst in the latter the necessary strength of the instrument is interfered with. The prac- tice of closing the open end of the catheter with a round plug attached to the stilette is unnecessary. The curve, already directed, of the front third of the instrument, is the most proper; the surgeon must, however, be provided with catheters of different curves, which are often necessary on account of the particular seat of the obstacle. Elastic silver catheters are useless. Elastic catheters, with a permanent curve, so that they can be introduced without a stilette, are in many instances advisable. The double S (shaped) curved catheter of Petit is of no value. Berton (a) recommends the use of catheters, one having a curve at an inch, and another at an inch and a half from its tip, so that the lengthening of the axis of the body of the instrument makes, with the prolonged axis of its vesical extremity, an angle, in the former of from 9° to 10°, and in the latter of from 14° to 15°. These curves do not exceed the smallest diameter of the urethra, which varies between three and four lines. (a) Archives Generates de Medecine, vol. xi. p. 66. 1826, May. 148 INTRODUCTION Straight catheters were already known to the ancients, as proved by those which have been dug up at Pompeii; they were but very little curved (a). Pare, also the two Fabricius, Rameau, Sietaud, Santarelli, and Cassus used straight catheters for men. Gruithuisen recommended, in 1812, straight sounds in his proposals for crushing stones; but of late they have been more particularly ad- vised by Civiale and Amussat. It is therefore remarkable that Fournikr (b) should have claimed the priority of discovery of straight sounds, because he has used them since 1815. [(1) I prefer the catheter with a very open curve, indeed with the point thrown out rather beyond the quadrant of the circle, as recommended by Chelius, so as to form with the stem, a curve represented by the long quadrant of an oval, of which the long diameter is double that of the short one. Most surgeons have a peculiar curve of their own, and those who have much practice in passing a catheter, soon find out that with which they are most dexterous. (2) The thickness of the walls of the catheter is a matter of great importance, be- cause unless sufficiently stout they are continually broken in the surgeon's altera- tion of the curve to suit the particular case which is often requisite ; and because, in passing the instrument, if it meet with much obstacle it is liable to be broken in the urethra, or even in the bladder. Catheters, as commonly made, are far too slight.—j. f. s.] 1815. The introduction of a catheter (Catheterismus, Lat.; Einhfuhrung des Kathders, Germ. ; Catheterisme, Fr.) is an operation requiring dex- terity and practice, and is not unfrequently accompanied with very great difficulty. It is best divided into three stages. In the first stage, the catheter passes through that part of the urethra contained in the spongy body. The surgeon grasps the penis behind the glans, with the thumb and forefinger of the left hand, without compressing the urethra. With the thumb, the fore and middle finger of the right hand he holds the up- per end of the catheter smeared with oil or lard, and introduces its point, whilst the handle is towards the navel, into the opening of the urethra, and then drawing the penis up with the left hand, he pushes the catheter down towards the perineum.. In the second stage, in which the instru- ment passes through the membranous part of the urethra, when the beak of the catheter has got beneath the arch of the pubes, the penis is let go, and the handle of the instrument being sunk slowly, and but a little, the catheter is now again pushed somewhat forwards, and in the third stage, when the beak of the instrument has reached the neck of the bladder, is the inclination towards the thighs first increased, and the catheter pushed slowly forwards into the bladder. When the beak has entered the ori- fice of the bladder, the handle of the catheter is at last sunk completely between the thighs. It is most convenient for the patient to lie on his back during the introduction of the catheter, but he may either sit or stand; and, not unfrequently, it is more readily passed in one posture than the other. The elastic catheter, properly curved, may be used either with or without the iron stilette. In the so called tour de mailre, the handle of the catheter is held towards the thighs, and with its convexity upwards, introduced into the urethra. When the beak lias reached the pubes, the handle is carried round towards the navel with a half turn, and then sunk. This handling is objectionable. In very stout persons the catheter must, at first, be introduced somewhat on one side. [For other observations in regard to passing the catheter, refer back to par. 1807 and par. 1811, and their notes.—j. f. s.] 1816. The introduction of the straight catheter requires the same three (a) Cassus, M^d. Opcrat., vol. i. pi. iii. (b) De PEnaploi dc Lithotritie, Sondes f. !• droiles, etc. Paris, 1829_ OF THE CATHETER. 149 stages as have been just described. The patient must kneel on the edge of the bed, with his thighs widely separated, and with the upper part of the body bent forwards, or he may stand or sit upon the edge of a stool in the same posture. The operator sits or kneels before him, and resting his left elbow upon the knee of the same side, grasps both sides of the penis with his left hand supine, draws it towards him horizontally and introduces with the right hand a straight catheter of proper size, carrying it with a drilling motion directly horizontal till it reach the arch of the pubes ; he then draws the penis still more forwards, and sinks it together with the catheter, till it has made a right angle without inclining it to- wards the perineum. The patient then bows himself considerably for- wards, so that the urethra and neck of the bladder are brought into a line, and the catheter instead of following the upper wall of the urethra slips into the bladder.—(Mohlin) (a). According to Amussat's plan (b), the surgeon, standing on the right side or between the legs of the patient sitting On the edge of a bed, with his feet on two chairs, draws the penis down with the left hand, till it be parallel with the-thighs, introduces the straight catheter with the right hand into the urethra, and readily up to the pubic arch ; he then draws the penis still more down, and holds the beak of the catheter directed upwards, which readily passes through the membranous part to the prostate. If the prostate be healthy, the hand only is usually sunk a little more, and the point of the instrument directed upwards to reach the bladder. If on the other hand the prostate be diseased, the operation is more difficult, and no positive rules can be given. It, however, seems in general to be more advisable not to sink the hand till'the instrument reach about the middle of the prostate; the point of the instrument also must be endeavoured to be carried on upon the upper wall of the urethra.—(Civiale.) 1817. The introduction of the catheter must always be performed with the greatest caution and tenderness; violence may cause severe inflam- mation, tearing the urethra, false passages, and great bleeding. The obstacles to the passage of the instrument are very various. If the handle of the instrument be sunk too quickly, its beak strikes against the pubic bones, and a firm resistance is felt: it must then be drawn back, and introduced rather deeper before the handle is again sunk. In difficult cases, it may be ascertained by the finger passed into the rectum, whether the catheter be beneath the pubic bones. If the instrument be introduced too low, or its beak be found in a wrong direction, when'it either pushes the membranous part into a blind sac, or thrusts against a fold of the internal membrane of the urethra, it must be drawn a little back, the ring on the right side of the handle attentively observed, and the catheter pushed forwards in the proper direction. The forefinger of the left hand passed uptherectum can sustain the proper direction of the instrument. The entrance of the catheter is often opposed by spasm, or by swelling of the prostate. In the former case the catheter is to be held quietly, the perineum rubbed, and then the instrument pressed forward in the proper direction. In swelling of the prostate, the method to be adopted has been already described {par. 1807.) Elastic catheters, when stopped by any obstacle, will often pass, if the iron stilette be withdrawn about an inch, and the catheter then pushed forwards. In strictures of the urethra, a catheter may sometimes be passed, if a bougie have been (a) Nouveau Traitement des Retentions d'Urine et des Retrecissemens de 1'Uretre par le Catheterisme rectilligne, &c. Paris, 1834. (b) P. Ecot, Dissert, du Catherine exerceavec la Sonde droite. Strasb., 1825. 4to. 150 OF PUNCTURING previously introduced, and allowed to remain some hours. In difficult cases catheters of different sizes must be used. 1818. When the catheter has entered the bladder it is known by its free motion, by the direction of its handle, which sinks between the thighs, and by the flow of the urine, when the stilette is withdrawn. If the flow be prevented by thick mucus or clots of blood, which get into the holes or into the canal of the instrument, the obstacle must be re- moved by injecting lukewarm water, or by introducing the stilette, or the water must be drawn off by a syringe attached to the outer end of the catheter. In paralytic retention, pressure upon the lower part of the belly is often necessary to empty the bladder completely. If there be much difficulty in introducing the catheter, it is best to let it remain; its aperture maybe plugged, and it maybe fastened by a double bandage and circles of sticking plaster around the penis. The urine must be allowed to escape every three or four hours ; and every six or seven days a fresh one introduced, so that it may not get too much softened and encrusted. If the patient cannot bear the inlying of the catheter, it must be introduced as often as needful. If a stiff elastic or silver catheter remain in very long, or if the urethra he shorter than usual, its beak may gradually penetrate the hinder upper wall of the bladder, and cause fatal peritonitis. In this case the urine begins to escape after five or six days, or it escapes between the urethra and catheter, and symptoms of peritonitis arise. To prevent this the catheter must be carefully fastened, not too closely, so that it do not penetrate more deeply than that the urine may escape by its side openings. This may be easily managed, if whilst the urine flows, the catheter be pushed a few lines in, and carefully fastened at the moment it cases to flow.— (Lallemand) (a). 1819. The introduction of the catheter in the female is much more easy than in the male. The patient being laid on her back, and her thighs somewhat separated, the forefinger of the right hand, with the catheter upon its volar surface, is passed between the labia towards the orifice of the urethra, which is distinctly felt with its tip as an aperture surrounded with a little puffy edge, and into it the catheter is passed. If it cannot be managed in this way, the parts must be exposed so that the orifice of the urethra may be brought into view. OF PUNCTURING THE BLADDER. 1820. When in consequence of retention of urine, the bladder is so greatly distended, that dangerous results, as mortification, tearing of the bladder, or extravasation of urine, are to be dreaded, and the voidance of the urine cannot be effected by the natural passage, there remains no other means of safety for the patient than emptying the bladder by arti- ficial means, or puncturing the bladder, (Paracentesis Vesice, Lat.; Blasenstich, Germ.; Ponction de la Vessie, Fr.,) as it is called. This operation is rarely necessary, if the introduction of wax or catgut bougies, elastic catheters, and a mode of treatment corresponding to the character of the retention, have been carefully pursued. It is, however, bad practice to dispense with this operation, by trusting to the violent introduction of the catheter, in cases of insurmountable obstacles in the (a) Perforation de la Vessie par les Sondes fixes: in Revue Medicale, vol. ix., p. 299. 1822, Nov. THE BLADDER. 151 urethra. Puncturing the bladder is not so dangerous an operation as by many supposed ; its danger is only much increased when it has been too long delayed. 1821. Puncture of the bladder maybe performed in three ways: first, above the pubes ; second, through the rectum, and in women, through the vagina; third, through the perineum, 1822. In puncturing the bladder above the pubes, the patient must be placed in a half sitting posture in bed. The hair of the pubes having been removed, an assistant fixes the bladder with both hands, and holds it in the mesial line, corresponding to the linea alba. The surgeon puts the nail of the forefinger of his left hand upon the upper edge of the pubic symphysis ; holds with the whole right hand a somewhat curved (Flurant's) trocar, lays his forefinger on its Convex surface, and. places it with the concavity downwards, close above the nail of the left hand upon the white line, and thrusts it through the walls of the belly into the bladder. When the trocar has penetrated from two and a half to four inches deep, according to the thickness of the walls, the operator grasps the tube with the fingers of the left hand, and draws the stilette out with the right. The urine now escapes by the tube, and being assisted by pressure on the belly, is gradually discharged. In order to prevent the sharp edge of the instrument injuring or irritating the walls of the bladder as it contracts, another silver tube with a blunt end is to be introduced thr'ough it, through the side openings of which the urine can escape ; its Other end is furnished with a stay. (a). For fixing the inner tube, a cleft compress is to be so applied, that the tube may lie in its cleft. The vertical part of a T bandage is to be crossed before and behind the tube and fastened to the girdle part. The outer tube must be fixed by bandages, drawn through the openings in its outer end, to the girdle-piece of a T bandage. To prevent the inner tube drawing back, tapes must be introduced through its rings, and attached to the openings of the outer tubes. The direction to thrust in the trocar an inch to an inch and a half above the pubic symphysis rests on the notion that the bladder, in its ascent above the symphysis, is separated from the hind wall of the belly. However, in puncturing high, the danger of wounding the peritonaeum is greater, and the bladder may more easily slip away, when it contracts, after the urine has been voided. In very stout persons, if the bladder be not very full, it may be proper to make a previous cut of an inch and a half long through the coverings in the same place above the pubic symphysis, in the white line, till the bladder can be distinctly felt with the finger. The curve of the trocar should be a segment of a circle of eight inches diameter (Desault;) its length must vary according to the bulk of the body, but should not be less than five inches. It is objectionable to introduce a second tube, with a rounded end, or a flexible catheter, through the first, and to withdraw it, as the urine will escape by the side of the smaller tube. 1823. After the operation, the urine must be discharged by the tube as often as is necessary. If inflammatory symptoms arise or continue, corresponding remedies must be employed. Towards the seventh day, the tubes must be removed to be cleaned. The inner tube must be first withdrawn, and then a curved steel cylinder having been introduced (a) Zang, Op rationen, vol. iii. pt. ii. pi. i. The same mode of proceeding, though with a different obj ct, is directed by D schamps, Traite historique et d.igmatique de la Taiillc, vol. iv. pi. viii. 152 PUNCTURING THE BLADDER, THROUGH THE RECTUM ; into the bladder, through the canula of the trocar, the canula must be drawn over it, and after having been cleansed, must be returned upon it. During the after-treatment, attempts must be made in every possible way to restore the natural passage for the urine. When this can be effected, and a flexible catheter have been introduced into the bladder, the tube may be withdrawn; and then, whilst the surrounding coverings are held back with one hand, the opening is to be covered with sticking plaster, and if it will not close, must be frequently touched with lunar caustic. In changing the tubes care is always necessary for a long while, because the union of the bladder with the hind surface of the abdominal muscles is frequently not suffi- ciently firm for a considerable time. A previous cut through the covering prevents this adhesion. When, therefore, the reopening of the natural passage is impossible, the trocar must be,thrust directly through the coverings, the tubes safely fastened, and the urine discharged less frequently through the tube, which must not be changed before the eighth, day, and then only with the greatest care, the patient kept quiet, and when union between tbe bladder and abdominal muscles has taken place, an elastic catheter maybe introduced into the bladder. Schreger (a) proposes, by means of loops introduced into the walls of the bladder, by the sides of the trocar tube, to bring them into contact with the walls of the belly, and encourage their union. Upon puncturing the bladder above the pubic symphysis, the following works may be consulted:— Mery; in Histoire de l'Academie des Sciences. 1701, p. 378. Bonn, above cited. • Mursinna, Neue medic.-chirurg. Beobachtungen, p. 391. Berlin, 1796. Palletta, Delia Punctura della Vesica orinaria; in Giorn. di Venezio, vol. ix. p. 217. Desault, GSuvres Chirurgicales, vol. iii. p. 317. Meyer, Dissert, de Paracentesi Vesicae. Urlang., 1798. 4to. Soemmering, above cited, p. 52. Schreger; in his Chirurgischen Versuchen, vol. i. p. 211. Abernethy, Surgical Works, vol. ii. p. 189. Kothe, Wiirdigung der Methoden des Harnblasenstiches; in Rust's Magazin, vol. xvii. p. 281. [Betton ; in American Journ. of the Med. Sciences, vol. xix. p. 389. 1836.—g. w. n.] 1824. In puncturing the bladder through the rectum, after having cleared the rectum with a clyster, the patient must be laid on the edge of a bed, so that the depending thighs may be bent and supported apart by assistants. The surgeon introduces his finger oiled into the rectum, about six lines above the prostate gland ; then carries the curved trocar, with its point retracted, upon it, to the part where the finger determines the puncture should -be made. The handle of the trocar is now sunk against the buttock, and at the same time the point thrust forwards out of the canula, and the trocar pushed in the axis of the pelvis to the depth of an inch to an inch and a half. The stilette is then withdrawn, whilst the left hand steadies the tube. The urine having flowed through the first tube, a second, with a rounded end, is introduced, and both fixed by means of a cleft compress and T bandage, and tapes drawn through the rings. The works which may be consulted on puncture through the rectum are Pouteau, Melanges de Chirurgie, p. 500. Lyons, 1760. (a) Above cited, p. 231. THROUGH THE PERINEUM. 153 Hamilton; in Philosoph. Trans., vol. xvi. Reid, A., An Enquiry into the merits of the Operations used in Obstinate Sup- pressions of Urine. London, 1778. 8vo. Klosse, Dissert, de Paracentesi Vesicae urina per intestinum rectum. Jena, 1791. 8vo. Home, Everard; in Trans, of a Society for the Improvement of Medical and Surgical Knowledge; and in Practical Observations on the treatment of Strictures in the Urethra and the Oesophagus, vol. ii. p. 329. Second Edition. Carpue, History of the High Operation for the Stone, p. 176. London, 1819. 8vo. 1825. Puncturing the bladder through the perineum, is the most ancient practice, but at present almost entirely given up. In this operation, either the urethra and neck of the bladder are opened directly by a cut in the perineum or the cut is made upon a staff, (boutonniere,) into the neck of the bladder, or the bladder is pierced with a trocar, which is thrust in either directly in the middle of a line supposed to be drawn from the ischial tuberosities to the raphe, two lines in front of the edge of the anus, the point of the instrument being directed first parallel to the axis of the body, and then thrust somewhat inwards; or a cut an inch and a half long is made half an inch to the left side of the raphe, begin- ning beneath the bulb of the urethra, and ending by the verge of the anus, through the cellular tissue and muscles; whilst an assistant presses the bladder down, the operator's forefinger of the left hand introduced into the wound, ascertained its position, and then upon it he carries a thick grooved trocar, directed somewhat upwards into the bladder. The urine having been discharged, the outer wound is lightly filled with lint, the tube plugged and fastened as in puncture through the rectum. For a careful recital of the various methods of proceeding in puncturing the blad- der through the perinaeum, see Poller, Ueber den Harnblasenstich in Damme. Erlang., 1813. 8vo. Upon the various modes of using the Sound, see Desault, above cited, vol. iii. p. 320. 1826. Although opinions agree upon the undoubted preference of puncturing the bladder above the pubic symphysis, and through the rec- tum, to that through the perineum, yet do they differ in regard to the first two modes of operation. In regard to puncture above the pubes, it is considered as easily per- formed and slightly painful; that by it merely the coverings of the belly and one part of the bladder are injured, where it usually is not inflamed, and where it can be best treated ; that the bladder cannot be missed, that the after treatment is easier, extravasation of urine does not so rea- dily occur, and the tubes if they accidentally fall out, can be easily re- placed, and may be changed and cleaned with little trouble; and that the patient can go about whilst they remain in. On the other hand, the slipping off of the bladder from the tubes after the discharge of the urine, by its falling together, and by the pressure on it, if it descend very low, inflammation and suppuration of the hind wall of the bladder, and thrust- ing the tube into the rectum, are to be dreaded ; also if the urine be not completely discharged, that a part of it always remains in the bottom of the bladder. For the preference of puncturing through the rectum, it is alleged that the walls of the bladder and rectum are in closer contact, that the trocar has no thick parts to penetrate, and therefore the operation is not painful; Vol. hi.—14 154 PUNCTURING THE BLADDER THROUGH THE PERINEUM. that the swelling of the bladder is more perceptible, and failure in intro- ducing the trocar less possible. On the contrary, it is thought that in this operation the bladder may be missed, a blood vessel, or the seminal vesicles, or the peritoneum wounded ; that its effects are always greater, the escape of the tubes, infiltration of the urine, collection of pus and con- sequent urinary fistula, are to be feared. 1827. The objections to the puncture above the pubes are of little value, as in performing it with a curved trocar, and by the introduction of a blunt tube, no injury to the hind wall of the bladder can ensue, and the escape of the urine can be furthered by the proper position of the patient. This mode of operation, therefore, serves generally, but is espe- cially preferable over that through the rectum in those cases where the bladder is inflamed or otherwise diseased, in hardening of the prostate, in diseases of the rectum, specially in hemorrhoidal swellings, and if the discharge of the urine through the operation-wound must be long sus- tained, Or throughout life. As to the objections made to puncturing through the rectum, it may be replied, that the injury of the seminal vesicles may be easily avoided by passing the finger in deeply, and thrusting the trocar directly into the middle of the swelling ;. that wounding the peritoneum is not easily pos- sible, because in the elevation of the bladder, the space between the prostate and that membrane is increased ; and the slipping out of the tubes, in many cases, cannot produce any inconvenience, as the urine either flows out through the opening, or the bladder again fills. The preference, however, of the puncture above the pubes always continues the greatest. As peculiar indications for puncturing through the rectum may be held, a very deep-seated bladder, effusion of blood into it, and an overweening dread of the patient about an operation, in which case it can be done through the rectum, without his knowledge. Poller (a), in cases where the operation above the pubes cannot be performed, prefers that through the perinaeum to the puncture through'the rectum, especially if it be foreseen that the retention of urine may be continued a long time after the ope- ration. In the puncture ihrough the perinaeum, there are also some special objects attainable, as the emptying calcareous concretions in permanent disposition to form stone, and the removal of the danger of ischury in consequence of large stones, which cannot be removed. [But few surgeons in England, I believe, at the present time, ever perform either of the operations for puncturing the bladder as above described, except in the single case of enlarged prostate, in which the operation above the pubes should be performed; and indeed as regards that disease, the necessity for any artificial assistance, beyond that of introducing a catheter, is so rare, that it is scarcely thougbt of. In all cases the operation of opening the membranous part of the urethra, and introducing a cathe- ter into the bladder, which is,, and has been for many years past, commonly prac- tised in this country, is the most satisfactory and the most effectual. If there be stricture, it is the surgeon's fault if the stricture and the retention be not cured at one and the same time; and, to a certainty it prevents the possibility of mischief from extravasation, as the urine speedily flows by the wound, and is never pent up. There is neither difficulty nor danger in this operation. With common attention, the urethra may, in most cases, be found, and a catheter at once passed into the blad- der. If it cannot be found, as occasionally happens with young operators, who cut light through the urethra before they are aware of it, if the cut be continued more deeply, the bladder must be opened, if the wound be carried up in the axis of the pelois; and if it be not opened, it is not matter of great consequence, provided there (a) Above cited, p. 47.—Mondiere ; in Revue Medicalc, vol. ii. p. 319. 1841. THE CESAREAN OPERATION. 155 be a free external opening, as in the course of a few hours the urine will find its way into the wound, and be readily discharged ; and in cases of stricture, if the stricture be so far forward that it be not involved in the wound in the perinaeum, made by the knife, or by sloughing, if urine be extravasated, it generally relaxes so much that it can be cured by the ordinary treatment with bougies, or sounds, during the repara- tion of the wound in the perinaeum.—j. v. s.] IV.—OF THE CESAREAN OPERATION. (Sectio Caesarea; Gastrohysterotomia, Leparo-Metrotomia, Lat.; Kaiserschnitt, Germ; Operation Cesarienne, Fr.) s Rousset, Traite nouveau de l'Hysterotomokia, Paris, 1581. Translated also into Latin by Bauhinus. Basil, 1582. Rulea, Traite de l'Operation Cesarienne. Paris, 1704. Simon, Recherches sur l'Operation Cesarienne; in Mem. de l'Acad. de Chi- rurg., vol. i. p. 623 ; vol. ii. p. 308. Kaltschmiot, De Partu Caesareo. Jen., 1750. Stein, G. W., Praktische Anleitung zur Kaisergeburt. Cassel, 1775. Weissenborn, Observations duae de Partu Caesareo. Erford., 1792. Frevmann, De Partu Caesareo. Marb., 1797. Hull, John, M. D., A Defence of the Caesarean Operation, &c. Manchester, 1798, 8vo. Gaillardot, C, Sur l'Operation Cesarienne. Strasb., 1799. Stein, G. W., Geburtshulfiiche Abhandlungen. Part I. Marb., 1803. Ansiaux, N., Dissert, sur l'Operation Cesarienne et la Section de la Symphyse des Pubis. Paris, 1803. Nettmann, J. F., Speciem sistens Sectionis Caesareas Historiam. Hall, 1805. Graefe, C. F., Ueber Minderung der Gefahr beim Kaiserschnitte nebst der Ge- schichte eines Falles, in welchem Mutter und Kinderhalten wurden; in Journal fur Chirurgie und Augenheilk, vol. ix. p. 1. Michaelis, G. A., Vierter Kaiserschnitt der Frau Adametz, mit gliicklichem Er- folge fur Mutter und Kind; in Neue Zeitschr. fur Geburtskunde, vol. v. p. 1. Ber- lin, 1837. Kavser, C, De eventu Sectionis Caesareas. Havniae, 1841. 8vo. Rigby, Edw., M. D., A System of Midwifery. London, 1844. 12mo. [Gibson, W., On Hysterotomy or Caesarean Section, in Institutes and Practice of Surgery, vol. ii. Philadelphia, 1845.—g. w. n.] 1828. When the pelvis is so narrow that a child cannot be brought into the world at all by the natural passages, or not alive, the delivery must be effected by some other than the natural way, that is, by the arti- ficial opening of the belly and womb. 1829. The circumstances demanding the Caesarean operation are first, when the antero-posterior diameter of the outlet of the pelvis is less than two and a half inches, and the child is alive ; second, when there is so great narrowing of the pelvis, that the dismemberment of the child is impossible. When it is not quite certain the child is alive, perforation should be preferred to the Caesarean operation; as it should be also in misformed children. If the mother be against the operation, her voice must be attended to. In doubtful cases, for instance, when the signs which declare for and against the life of the child are of equal value, the choice of the operation is not to be left to her decision, if she resolve upon it during the labour. [" The difficulty of deciding upon the operation, according to the indications of the Continental practitioners, is," observes Rigby, "much more perplexing than ac- cording to that which is followed in this country. The question here is, can the child, under any circumstances, be made to pass per vias naturales with safety to the mother ? The impossibility of effecting this object is the sole guide for our decision. 156 THE CESAREAN OPERATION. In using the operation as a means for preserving also the life of the child, we must not only feel certain that the child is alive, but that it is also capable of supporting life, before.we can conscientiously undertake the operation upon such indications. This uncertainty as to the life or death of the child greatly increases the difficulty of deciding. Under circumstances where there is reason to believe that, although the child may be alive, it is, nevertheless, unable to prolong its existence for any time, and the pelvis so narrow that it can only be brought through the natural passage piecemeal, we are certainly not authorized in putting an adult and otherwise healthy mother into such imminent danger of her life, for the sake of a child which is too weak to support existence. Circumstances may, nevertheless, occur, where the pelvis is so narrow that the child cannot be brought even piecemeal through the na- tural passage; in this case, even if the child be dead, the operation becomes unavoid- able. Under the above-mentioned circumstances, it is the duty of the surgeon to perform the operation; and he can do it with the more confidence, from the know- ledge of many cases upon record, where it has succeeded, even under very unfa- vourable circumstances, and where it has been performed very awkwardly; more- over, it seems highly probable, that the unfavourable results of this operation can- not often be attributed to the operation itself, but to other circumstances. Not, unfrequently, the uterus has been so bruised, irritated and injured, by the violent and repeated attempts to deliver, by turning or the forceps, and the patient so exhausted, and brought into such a spasmodic and feverish state, by the fruitless pains and vehement efforts, together with the anxiety and restlessness which must occur under such circumstances, that it is impossible for the operation to prove successful." (pp. 154, 5?.)] 1830. In a pregnant woman just dead, the Cgesarean operation should be performed, if pregnancy be so far advanced, that the child is capable of living, if the delivery be not possible by the natural passages, and the mother actually, not apparently, dead (a); in which case the operation must be undertaken as quickly as possible. [The importance of the actual death of the mother being put, beyond all doubt, previous to undertaking the operation, under these circumstances, cannot be too strongly impressed. A medical friend, on. whose veracity I can rely, told me of an instance in which a practitioner in the country, presuming that a pregnant woman labouring under typhus fever was dead, began the performance of the Caesarean ope- ration, the pain of which arousing her from her dead-like state, she screamed out, and soon died. He lost his practice, and was obliged to leave the place.—j. f. s.] 1831. The Cesarean' operation, partly on account of the very large wound it inflicts, partly on account of the symptoms which follow after, is'a most exceedingly dangerous operation. The number of patients saved is very few, in comparison with those who have died after it. Cases, however, are mentioned, where the operation has been performed two, five, six, and seven times, upon the same person {b). A more favourable result is to be expected, if the patient's health be good; if she have not suffered from previous disease, fruitless labour-pains, or artificial attempts at delivery, and if the operation be undertaken at the right time. [MIchaelis, who has very carefully inquired into the subject, has considerable doubts of the authenticity of many of the cases of repeated Caesarean operation on the same,woman, which have been related by the writers of the seventeenth and eigh- teenth centuries; for, as he observes, "it must be considered remarkable that no writer, as it seems, relates*the circumstance at first hand, that is, from the surgeon himself; for in No. 3, (the woman who stated she had been operated on thrice,) No. 7, (the ship's captain who declared himself the sixth son of whom his mother (a) Rigaudeaux ; in Journal des Scavans, Sommer ; in Rnssischen Sammlungen fur 1749. Naturwissenschaft und Heilkunst, vol. i. pt. (6) Simon; above cited, p. 636.—Le Mai- iv. Leipz., 1817.—Lochek, J. T., M. D.; in stre ; in Journ. de Medec, vol. xliv. 1812.— Med.-Chir. Trans., vol. ix-xi. p. 182. THE CESAREAN OPERATION. 157 had been delivered by this operation, and that she died in her seventh pregnancy, because the surgeon who had previously operated on her was deceased,) No. 8, (the Minorite, the fifth son of another in this same way delivered of all her children,) and No. 9, (the woman mentioned by Count Tressan, who had been delivered by the Caesarean operation seven times,) the woman, or the sons who related it, are not of sufficient credit. To this must be added, that some of these histories rest alone upon hearsay, or onsuspicious witnesses. Thus was it, for instance, with Count Tressan's case, at a time when, at least in France, literary intercourse was very ac^- tive, that it seems incomprehensible how BAUDEL0CQUE,in the Recueilperiodique de la Soc. de Med., vol. v. p. 63 to 74, in which he gives a collection of sixty-six cases, from the year. 1752 to 1799, should never at all have thought of this most remarka- ble case of all; and it is almost beyond belief, that it should remain' for Count Tressan to discover such a case." (p. 5.) "This inquiry, therefore, leads to the single result, that the old cases of often-repeated Caesarean operation must at least remain very doubtful. If, however, we be disposed to give credit one way or other, yet there is little benefit to knowledge from the want of old precise data, as, on the whole, the case of Adametz alone shows the possibility of an often repetition of the operation." (p. 6.) The most satisfactory inquiry into the result of the Caesarean operation is that made by Kayser (a), who divides the history into two periods; the former termi- nating with Simon's Essay in 1749, and the latter from 1750 to the publication of his own paper. Of the two hundred and fifty eight cases collected in the first period by Michaelis, to some of which reference has been already made, several rest on very slender authority. Of the three hundred and thirty-eight cases in the second period, one hundred and twenty-eight had a fortunate result, as regarded the life of the mo- ther; whilst two hundred and ten terminated fatally; or a mortality of 62 per cent. It appears, however, from the following table, that the fatality of the operation has been diminishing since 1750:— From 1750 to 1800 there were 37 successful 80 fatal cases. „ 1801 „ 1832 „ 54 „ 94 „ „ 1833 „ 1839 „ 37 „ 36 „ 128 210 Or in a decreasing ratio of 68, 63, and 49 per cent. Where labour had lasted more than seventy-two hours, the mortality was 72 per cent.; in those where it had continued a less time, only 61 per cent. According to Kayser's inquiries, it appears, that " in one hundred and twenty- three cases the cause of death was stated with more or less accuracy ; and it appears that seventy-three women died from inflammation, or its consequences, and twenty- nine from the shock to the nervous system. Internal haemorrhage occurred in ten, in whom coagula of blood were found in the abdomen; two died from external haemorrhage, two from pneumonia, one from rupture of the uterus, and consequent haemorrhage, on the seventh day after delivery; one died from osteomalacia, and one from the immediate effects of the operation, only twenty-four hours after its com- pletion." (p. 129.) Michaelis's own case is the most remarkable and best authenticated of any that have been published. The woman was delivered four times by the Caesarean operation. The account of the first three is given by Feist (b), and of the fourth by Michaelis himself (c). The woman was born at Wilster, in Holstein, in 1795, and was so ricketty that she was only able to walk a little when in her twelfth year. She became pregnant, and on the morning of the 18th June, 1826, all other means of delivery being inefficient, the Caesarean operation was performed by Dr. Zwanck, of Eddelack. (a) Cited at the head of the article. lam list as complete as possible of all well au- very sorry that I have been unable to lay thenticated cases) is by no means new, but hand on this Inaugural Essay; and am, it has never been executed so well as by therefore, compelled to refer to the very Kayser." I hope, however, at a future oc ■ meagre extracts from it in the British and casion to be more successful.—j. f. s. Foreign Medical Review, vol. xiv. p. 199, (b) Neue Zeitseh. fur Geburtskunde, vol. 1842, in which the reviewer observes :—" It iii. is true that this task (that of presenting a (c) Cited at head of article. 14* 158 THE CESAREAN OPERATION. The placenta was separated and removed immediately after the child, which appeared to have been some time dead, had been extracted, the womb contracting strongly; but this was followed by a severe bleeding, which was stopped by dropping cold water from a sponge, at a height of some feet. The edges of the external wound fell so completely together that there was not need of sutures, and sticking plaster was alone applied. Shortly after three weeks it had healed; before a month she left her bed, and two months from the operation menstruated. On the 21st Jan., 1829, she was again in labour, at the Lying-in Hospital at Kiel, where the Caesarean operation was performed on her by Wiedemann : the child was born alive. The external wound was brought together with three stitehes and sticking plaster, and a small tent left in the lower angle of the wound. On the 21st Feb. she got up from her bed for some hours, and was very well. In the beginning of March the wound was perfectly healed, except a few points of skin and a small sinus, which had not healed when she left the house at the latter end of that month. On the 28th March, 1832, she was in Kiel Lying-in Hospital, again subjected to the Caesa- rean operation, which was performed by Michaelis, and the child born alive. The womb contracted imperfectly on the removal of the after-birth, and there was then first a slight flow of blood from the womb, which was stopped in a few minutes by a stream of water from a sponge. Four sutures were put into the skin-wound, with a small portion of linen into its lower angle, and sticking plaster afterwards applied with a circular roller. The wound was healed, excepting a very small part of the scar, by the 16th May; but on the 25th, a small fistulous passage was discovered running into the womb, which had become firmly adherent to the walls of the belly. On the 10th June the fistula was healed (a)]. 1832. The favourable time for this operation is that at which nature would, under other circumstances, expel the foetus ; when, for instance, mucus, streaked with blood, flows from the generative parts; when the mouth of the womb is wide open, the waters have escaped, the head or any other part of the child is perceptible, and the labouring woman has suffered already actual, painful, quickly following labour-pains, nearly approaching convulsions. (Graefe.) ["Although it is so important," says Rigby, "that we should lose no time, still, nevertheless, it does not appear desirable to operate before labour has commenced, to any extent; for, unless the os uteri has undergone a certain degree of dilatation, it will not afford a sufficiently free exit for liquor amnii, blood, lochia, which, by stagnating in the uterus, after the operation, would soon become irritating and putrid, in which case they would be apt to drain through the wound, and create much mis- chief." {n. 155.)] 1833. The preparation for the operation consists in emptying the rectum with clysters, and the bladder with a catheter. The instruments required for this operation are a convex-edged and a button-ended straight bistoury, a director, bandages, and several needles. The position of the patient should be horizontal, upon her back, with the upper part of her back somewhat raised, on a narrow table, covered with a mattress; she should also be covered with a cloth at those parts not interfering with the operation, and should be held by assistants. Her face should be turned from the operator, or covered with a thin cloth. 1834. To prevent the protrusion of the intestines through the wound in the walls of the belly, moderate pressure with the hands is usually employed. Auterieth proposes the previous introduction of ligatures before the womb is opened, and Rietgen, a girdle of plaster. Graefe more properly makes well-regulated pressure with three sponges, each a foot long, six inches wide, and three inches thick, held by assistants, so (a) Michaelis, G. A., M. D., Abhandlungen aus dem Gebiete der Geburtshulfe. Kiel, 1833, large 8vo.; with eight plates. Extracts from the same in Neue Zeitsch, fur Geburt- skunde» voL iii. p. 438. By Feist of Mainz. THE CESAREAN OPERATION. 159 that a space about eight inches long, and from three to four wide, is left clear. If intestines be found between the womb and the wall of the belly, which may be ascertained by the yielding elastic condition of the latter, they must be first thrust back by gentle pressure, till a convex, unyielding firm hard bpdy be felt in every direction. At the very moment when the last part of the child escapes, the sponges must be more firmly pressed, by the assistants. 1835. The seat and direction of the cut has been variously proposed. First. The Lateral Cut, on the side where there is the greatest prominence of the belly, or, directly opposite it (a), by the side of the white line, more or less distant from it, in or near the m. rectus abdo- minis, between the navel and the pubic bones, and a little obliquely from above downwards and outwards (b). Second. The Cut in the white line, beginning from above or below the navel, to an inch and a half or two inches above the pubic symphysis (c). Third. The Transverse Cut, upon the side, where the womb is most prominent between the m. rectus and the spinal column, and between the false ribs and the crest of the hip-bone, above or below the navel {d). Fourth. The Oblique or Diagonal Cut, the direction of which is from the extremity of the lowest false rib to the horizontal branch of the pubic bone of the other side, obliquely across the white line, so that the middle of the cut falls immediately upon it. (e). 1836. The choice and direction of the cut, with its accompanying advantages, are not in general determinate, but must be guided by the particular circumstances of the case, especially by the position and direction of the womb, the pretty well known seat of the placenta, the position of the child, the size of the space between the navel and the pubic symphysis, and the like. As the placenta is most usually on the right side, though it may be also on the left, preference has been given to the cut on the left side rather than to that on the white line. In this cut the outer and inner walls are parallel, all fluids escape more readily from the wound; the wall of the belly is at this part thinnest; in open- ing it no blood vessel is wounded, and the healing of the wound in the linea alba is as quick as in any other partnf the wall of the belly. In the diagonal cut the womb, after the operation, contracts so that the wound in it does not gape. The same also happens with the oblique cut; in it, however, the wall of the belly is cut through at its thickest part, and vessels are wounded. That part is to be specially considered as the best where the womb and the child can be most distinctly felt. 1837. The operation consists of the following steps :—first, the open- ing of the belly-wall; second, the opening of the womb; third, the (a) Millot, Observation sur l'Operation (c) Guerin, Histoire de deux Operations dite Cesarienne, faite aver succes. Pari?, Cesariennes. Paris, 1750.—Baudelocque, 1796. Observations sur les Causes et les L'Art des Accouchemens, vol. ii. Paris, Accidens de plusieurs Accouchemens la- 1807.—Deleurye, Observations sur l'Opera- borieux. Paris, 1750. 8vo. Second Edition, tion Cesariennes a la ligne blanche. Paris, (b) Rousset, above cited.—Levret, Ob- 178B. eervations sur les Causes et les Accidens de (d) Lauverjat, Nouvelle Methode de plusieurs Accouchemens laborieux. Nouv. pratiquer l'Operation Cesarienne. Paris, Edit. Paris, 1780. 8vo—Stein, Abhand- 1788. lnnar von der Kaisergeburt. (e) Stien, Geburtshulfliche Abhandlungen. vol. i. p. 125. s 160 THE CESAREAN OPERATION. drawing forth of the child and of the after-birth ; fourth, the closing of the wound. 1838. The skin and abdominal muscles are to be cut through to the peritoneum in one of the directions given, {par. 1835,) with a convex bistoury. Any vessel wounded must be tied; a small opening is then made into the peritoneum to admit the forefinger of the left hand, and upon it the button-ended bistoury is introduced and divides the perito- neum the whole length of the outer wound. A cut is then made in the white line, as no vessel can be there wounded, bearing in mind the thin- ness of the expanded wall of the belly, with one stroke through the coverings and peritoneum. A length of five inches for the cut in the wall of the belly is sufficient, and of four and a half inches for that in the womb is generally to be considered sufficient. The womb now present- ing itself in the wound, of a bluish-red colour, its cavity is to be cut into with the convex bistoury to a small extent, and the wound enlarged in the direction of the outer wound, as quickly as possible with the button- ended bistoury introduced on the forefinger. The child, grasped accord- ing to its position, by the head or feet, is to be drawn out, but not too hastily, and the navel-string tied and divided. If the opening of the womb fall upon the middle of the placenta the cut must be quickly en- larged, the placenta cut through, the child pulled out, and the placenta separated. If the cut light upon the edge of the placenta, it must be separated. If the separated placenta present itself in the wound of the womb, it must be separated by a gentle pull upon the navel-string and by a not very quick twist. If this be not sufficient, it must be separated by introducing the hand into the womb. Wigand's (a) proposal of pushing the navel-string with a curved rod through the mouth of the wound into the vagina is objectionable. If the womb do not, by its own contraction, descend into the pelvis, it must be cautiously thrust down (6). Various kinds of knives for the Caesarean operation have been recommended by Stein (c), by Flammano, with a removeable sheath (d), by Zeller (e), and Mes- nard's knife and scissors (/). 1839.' After the blood, which has escaped into the cavity of the womb, has been sopped up" with fine sponge dipped in warm water, the mem- branes, which by stopping up the mouth of the womb prevent the flow- ing away of the blood, are to be removed, the blood poured into the belly gently pressed out, and any of the intestines which have protruded having been replaced, the edges of the wound are brought together by the assistants, and closed with the sutures {g), which are introduced with needles of sufficient breadth, in such way, however, that the lower angle of the wound, in which a strip of oiled linen is to be placed, may remain open for the escape of fluid. To support the closed wounds, some pieces of sticking plaster, from four to five inches and a half in width and length, are to be put on, and once and a half surround the belly, their middle placed on the back, and the ends brought forwards crossing in (a) Drei Geburtshulfliche Abhandhingen, p. 96. Hamburg. 1812. (b) Geburtshulfliche Abhandlungen. (e) Schnetter's Verzeichniss der chirurg. (c) Anleitung zur Geburtshillfe, pi. vi figs. Instrumente. 3, 4. Fifth Edition. (/) Krombholz's Akologie, pi. v. fig. 30, (d) Dissert, de l'Operation Cesarienne. pi. vi. fig. 1844. Paris, 1811. (g) Graefe, above cited, p. 25* THE SjESAREAN OPERATION. 161 front upon the wound and fixed obliquely below. The open part of the wound below is to be covered with wadding spread with ointment, and over it sticking plaster, and the whole belly supported with a linen girdle, having strings in front. The patient is then so placed in bed that the lower angle of the wound may, as far as possible, be the most depending part. [In a case operated on by Godefroy of Mayence (a), after the womb had con- tracted the edges of the wound did not come together, but a considerable space remained between them ; he therefore passed some sutures of waxed double threads, with a needle, through the whole thickness of the womb. The wound in the wall of the belly was also brought together by passing the needle through its whole thick- ness, and also through the peritonaeum. On the eleventh day, the union of the wound appearing firm, the sutures were removed. On the twenty-ninth day no trace of suppuration remained, and the patient left her bed. She recovered, and her child had been saved. Objections have been made by Desormeaux to sewing up the womb, but Godefroy thinks their danger is exaggerated. " The most dangerous circumstance in this (Caesarean) operation is," observes Michaelis, " the ijnpossibility of preventing completely the effusion of the secretion from the wound into the belly. The choice of the seat of the operation, as nearly as possible parallel to the white line, seems to be always the most important point, for there most rarely do the two wounds separate from each other. I have already mentioned, in another case (b), the remarkable circumstance that the wound in the womb lies transversely, and sinks to the lowest angle of the wound in the wall of the belly; and in other instances I have observed still more remarkable varieties in the wound and its fatal consequences. It may be hoped that this more frequent separation would not be so injurious, as the secretion of the wound discharges itself through the mouth of the womb and the vagina. The form which the wound as- sumes in consequence of the contraction of the womb is, however, unfavourable for this escape; it gapes externally, and lies close together within. Thus was it in my case, in which the whole wound in the womb remained long open, and was in general supported by purely mechanical means. But when the after-pains very soon subside the womb may so close, in consequence of general turgescence, before the oncoming of suppuration, that the cure is quick and without suppuration. It is therefore important that the after-pains should be very early put a stop to, if possible, by the moderate, or even the more active use of opium." (p. 24.)] 1840. The after-treatment must be the same as that generally laid down for large wounds of the belly, the state of the patient in regard to her puerperal condition being borne in mind (c). The dressings must be replaced when the secretion from the wound has penetrated through, or if there be any strangulation of the intestines or omentum. The re- moval of the sutures, if not previously required on account of inflamma- tion, should not be before the eighth or tenth day, first indeed, the upper, and afterwards the lower ones. The vagina and mouth of the womb should be examined every day, and every thing removed which can in- terfere with the lochial discharge. When scarring begins, a well-closing belly-band must be employed to prevent abdominal rupture, and all ex- ertion avoided. [Michaelis observes, in regard to opium:—"The employment of opium, at first in large, and afterwards in small doses, I consider the most important remedy for the purpose of guarding the nervous system before it become affected by so great an injury as the operation, for moderating the pain and for diminishing reaction." And as to the necessity of keeping the bowels freely open, he says, that "his own expe- rience, and his observation of other cases, have disposed him to it; that there is scarcely a fully described successful case in which the relief of the bowels has not (a) Gazette Medicale, vol. viii. p. 444. (b) Pfaff; Mittheilungen, vol. ii. p. 119. 1840. (c) Upon the after-treatment, see Graefe. 162 THE CESAREAN OPERATION. been frequent, indeed where there has not been severe diarrhoea. Adametz had the bowels moved on the last occasion, from the third to the twentieth day, almost daily six times, and on the fourth day nineteen times; that this was excessive I will not deny; the inconvenience, however, was trifling, and, indeed, had there not been on the fourth day so great a discharge she would have been with difficulty saved. It is, however, difficult to effect the relief at the proper time with the usual means. I believe, however, that we have in ice the safest and, in other respects, the most pro- per remedy; it at once operates quickly as a purgative if some doses of calomel be given with it." (pp. 25, 6.)] 1841. The following special proposals to diminish the danger of the Caasarean operation may be here mentioned;—First. The head of the child should be pressed up against the front of the womb and the belly by the hand passed through the pelvis up into the womb, and upon it and the white line, the cut made as far as necessary in order to hasten the expulsion of the child (a). Second. After the wound is made in the wall of the belly, immediately the womb, the vagina, and, if necessary, the*mouth of the womb should be opened at a single cut, and the child drawn out of the womb {b). Third. According to Rietgen (c), a semi- lunar cut should be made from the crest of the hip-bone to near the pubic symphysis, through the skin, whilst an assistant, standing at the patient's left breast, thrusts down the womb from the right side, by which the skin over the region of the wound is stretched. A cut of similar extent through the muscles follows that through the skin, care being taken not to wound the peritoneum. The cellular tissue covering the peritoneum is to be loosened with the fingers, with the handle of the knife, or with the knife itself, and the cavity of the belly undermined. The straight director is now introduced into the vagina, and so directed that its point pushes the vagina above the middle of the right linea innominata. The operator now thrusts the stem of the director through the wall of the vagina, and enlarges the opening with a button-ended bistoury towards the bladder. The director is removed and the cut continued towards the rectum upon the right forefinger. If the cut can be so made that an edge of two or three inches of the vagina be formed on the right half of the neck of the womb, it must be divided obliquely with the scissors ; the wound is then covered and the passage of the child watched. If necessary, the womb also may be cut into on the right side. Rietgen (d) considers that the wound in the walls of the belly, made as above directed, gives but little width, on account of the oblique direction of the descending fibres of the external abdominal muscle, and that for the extraction of the child a second cut is necessary to divide those fibres transversely. Cutting into the mouth and neck of the womb seems in no case to be dispensed with, and after the first cut has been made through the cavity of the vagina, must be immediately proceeded with. By thus doing, the division of the hind part of the vagina is unnecessary,and the considerable bleeding which accompanies it is thereby prevented, and what there is may be easily and completely stanched with a sponge dipped in cold water. The best chosen part for the cut into the womb is under that fold of the peritonaeum which passes upon the round ligament of the womb, and partly lies upon it. Astley Cooper's hernial knife answers best for opening the womb. (a) Oslander ; in Gott. gelehrt. Anzeig., fen bei Entbindungen, p. 441. Giesseu, 1813. 1820. (6) Jorg, Versuche und Beitrftge, p. 263. (d) Geschicbte eines mit unganstigem Leipz., 1806. Erfolge verrichteten Bauchscheidenschnittes (c) Die Anzeigen der mechanischen Hul- und Folgerungen daraus; in Heidelberger klinischen Annalen, vol. i. p. 263. THE CESAREAN OPERATION. 163 Baudelocque's (a) method agrees almost completely with that of Rietgen. He makes in the right-sided obliquity of the womb a cut upon the left side of the belly along the outer edge of the m. rectus, from the navel to an inch or two above the symphysis. The waters are discharged through the vagina, the legs and thighs bent, and, with the finger introduced at the lower part of the wound, the peritonaeum is separated throughout the whole extent of the iliac pit, and above the iliac artery. One assistant then draws back the peritonaeum and intestines, and another keeps the womb in its place by his hand applied to the belly. The operator introduces his hand into the wound, seeks for the iliac artery, and ascertains whether any branches pass from it around the vagina, and if there be, they must be tied before he cuts through them. The left hand smeared with oil is now carried into the vagina, which is to be lifted into the wound, and then cut into as low down as possible below its insertion into the neck of the womb, and the cut lengthened to four inches and a half. In left-sided obliquity of the womb, the cut is to be made on the right side. Baudglocque calls this operation Gastroelytrotomy. Physick (6) proposes making the cut horizontal above the pubic bones, and to dig here beneath the peritonaeum. Experience has'not yet decided on the value of these several methods, especially upon the various difficulties in bringing the child into the world. The advantage of not opening the cavity of the belly is counterbalanced by the tearing away and separating the peritonaeum, from which dangerous inflammation, effusion, and col- lection of pus would necessarily ensue. [From the account which Michaelis has given of the woman Adametz, it is evi- dent that, with good reason, he considers a repetition of the operation as more likely to be successful than the first, on account of the adhesions which the womb acquires to the wall of the belly. He observes, that "the growing together of the walls of the belly with the womb had the most favourable influence upon the subsequent operations. This union had already taken place, at the second operation, at one part; in the third, three places had united; in the fourth, the union was complete as far as the cut extended.. But I consider that even a partial union has an important influence, by preventing the wound of the womb separating so far from the wall of the belly, that the secretion from the former cannot find a free passage into the latter. It has also the advantage in this operation that if it (the adhesion) be above, the intestines cannot protrude there, but if it be complete, there can be no protrusion. This would be a very untoward condition, if Merrem^'s opinion (c) were correct, that 'in the adhesion the wall of the belly, in the latter half of pregnancy, there would be tearing from the little extensible belly-wall, and thus the flying open of the whole imperfect scar of the womb would necessarily occur; and that 'in such cases it was not to be supposed that the foetus would be carried its full time.' MeIrrem, on the one hand, draws his conclusions from one single case; but nature, on the other, has other means than theory imagines. These are, that the adherent wall of the belly, or the scar, possesses the same extensibility as the womb itself. The first wound of five inches had, in the second pregnancy, lengthened itself to ten inches, and was four inches broad. In the third pregnancy it was twelve long, and five inches broad; and in the fourth pregnancy still larger. The contraction of the scar after the fourth pregnancy was most surprising,'for although the cut itself after some days had diminished to half its length, although it at last diminished from five inches to one, yet was the wall of the belly, at the part where the womb adhered, smooth and free from fold; but where it did not adhere, were two slight transverse folds." (pp. 22, 3.)] (a) These Inaugurate. Paris, 1823 ; and (fc) Dewf.es, Compendious System of Mid- Nouveau Moyen pour delivrer les femmes wifery. Philadelphia, 1824. contrefaites a terme et en travail, substitue (c) Gemeinde Zeitschr. fur Geburtsk., vol. a l'Operation Cesarienne, suivi de reflexions iii. p. 338. sur ce sujct, par F. T. Duchateau. Paris, 1824. &vo. 164 GASTROTOMY. V.—OF GASTROTOMY. (Gaslroiqmia, Laparotomia, Lat.; Bauchschnitt, Germ.) 1842. If a foetus be developed in the Fallopian tube, in the ovary, or in the cavity of the belly, or if by bursting of the womb or vagina, it escape into the cavity of the belly, and its extraction cannot be effected by the natural passages, dangerous symptoms in regard to the mother are to be feared whether the child be alive or dead, and there be no signs that it can be discharged by the process of ulceration in one way or other by the natural powers, then opening the cavity of the belly is required' The other diseases which render this operation necessary have been already mentioned. The symptoms of an extra-uterine pregnancy are never so manifest, that before the usual period of delivery the operation can be decided on; although, if it can be performed between the second and fifth month, the hope of a successful result is by far greater than when it is undertaken at the ordinary termination of pregnancy; for in these cases the abdominal' bowels are always considerably altered, the whole constitution of the patient is greatly disturbed ; it is not certain that the placenta can be completely separated; and in the separation of the membranes, dangerous bleeding is always to be dreaded. In what way also is the lochial discharge to be got rid of? It must also be remembered that the foetus, in extra-uterine pregnancy, very rarely reaches the full period, that on the contrary it not unfrequently remains enclosed and crumpled up in the membranes, which are thickened and hardened; or that in consequence of the irritation of the foetus, inflammation, adhesion of the neighbouring parts, and throwing off the foetus, piecemeal, by suppuration, through the openings of the abscess or by the rectum, may happen; so that, in most cases, it may be best to assist nature in the discharge of the foetus, in the way just men- tioned, by means which encourage suppuration, and the like. According to Heim (a), most violent pains, and the most pitiable and deplorable condition may exist, and in one case did for ten years. [It is an important question, whether a womb can be ruptured completely, excepting its peritoneal coat, within which'the foetus may be still retained, and so found by the operation of gastrotomy. Blundell (b) thinks it can, and gives us an example Barlow's (c) case, in which it is stated "the uterus was very thin, scarcely exceeding that of the peritonaeum, and equally so throughout the whole extent of the incision." (p. 159.) Hull (d), however, considered "that the child had escaped through a laceration of the uterus into the abdomen, enveloped in the secundines, and that Barlow had merely divided the membranes, when he fancied he had divided the uterus." (p. 73.) But Blundell says :—"To me it appears to have been a case of rupture of the muscular substance of the uterus, without rupture of the uterine peritonaeum." (p. 552.) Under such circumstances the operation per- formed would be merely gastrotomy, and not the Caesarean.] 1843. When in a tabular or ovarian pregnancy the membranes en- closing the foetus are torn, or by a rent of the womb, the foetus escapes into the cavity of the belly, in which latter case the patient, after severe suffering and labour-pains, feels suddenly easy, and has a sensation of warmth spreading over the belly, the pulse small and quick, and the like, death in general soon follows. 1844. No definite rules can be laid down for the place and direction of the cut. At the part where the foetus is most distinctly felt, and (a) Erfahrungen fiber Schwangerschaften (c) Medical Records and Researches. ausserhalb der Gebarmulter; in vermischten London, 1798. 8vo. Med.-Schriften, p. 368. Berlin, 1836. (d) Defence above cited. (6) Lectures on the Theory and Practice of Midwifery; in Lancet, 1837-38, vol. ii. CUTTING THROUGH THE PUBIC SYMPHYSIS. 165 towards which an assistant should press it with his hands spread flat on both sides, a cut of about six inches long should be made through the skin and muscles down to the peritoneum, which must be then divided, as in the Cesarean operation. If the foetus be uncovered by the mem- branes, it may be removed in any convenient way; if it be enclosed, the membranes must be cautiously separated, the foetus, and afterwards the membranes, if not prevented by adhesion (a), and the placenta removed. If the foetus be partly in a rent of the womb, it must be taken out cleverly, if possible without enlarging the rent. If separation of the placenta be impossible, the navel-string, after having been tied, must be left hanging out of the wound till the placenta come away. The dressing and after- treatment are the same as in the Ceesarean operation. 1845. If an abscess or fistulous opening have already formed, it must be cut into or enlarged for the purpose of removing the foetus whole or piecemeal {b). VI.—OF CUTTING THROUGH THE PUBIC SYMPHYSIS. (Synchondrotomia, Lat.; Schoosfugenschnitt, Germ.; Symphyseotomie, Fr.) Camper, Epistola de emolumentis Sectionis synchondroseos Ossium Pubis. Groening, 1774. Sigault, Discours sur les avantages de la Section de la Symphyse du Pubis. Paris, 1778. Leroy, A., Recherches historiques et pratiques sur la Section de la Symphyse du Pubis. Paris, 1778. Leroy, Observations et reflexions sur l'Operation de la Symphyse et les Accouche- mens laborieux. Paris, 1780. Piet, Pensees sur la Section de la Symphyse des Os Pubis. Paris, 1778. von Krapf, K., Anatomische Versuche und Anmerkungen iiber die angebliche Erweiterung der Beckenhohle, u. s. w. Part I. Wien., 1780. Part II., 1781. Siebold C.,etWeidmann, Comparatio inter SectionemCaesaream,etDissectionem Cartilaginum et Ligamentorum, Pubis in partu, ob angustiam Pelvis, impossibili. Wirceb., 1779. Walter, von der Spaltung der Schaambeine in schweren Geburten. Berl., 1782. Micheli, J. P., Dissert, inquirens Synchondrotomiae utilitatem in Partu difficili. Lugd. Batav., 1781. 4to. JDesgranges, Remarques critiques et Observations sur la Section de la Symphyse des Os Pubis; in Journal de Medecine, p. 481. 1780. Lauverjat, Nouvelle Methode de pratiquer l'Operation Cesarienne et Parallele de cette operation et de la Section de la Symphyse des Os Pubis. Paris, 1788. Baudelocque, An in Partu impossibili Symphysis secanda1? Paris, 1776. Salomon, Verhandeling over de Nettigheit der Schaambenschneede, etc. Am- sterdam, 1813. 1846. Cutting through the pubic symphysis is required in a narrowing of the antero-posterior diameter of the outlet of the pelvis of from two and a half to three inches, and in a narrowing of the transverse diameter of the brim and outlet of from two to three inches. To lay down determinate indications for cutting through the pubic symphysis is difficult, as the experiments which have been made upon the enlargement of the pelvic dimensions, after division of the symphysis in dead bodies, have presented (a)VEiEL; in Wurtemb. Med. Correspon- novissimoque ejus exemplo. Viteb., 1811. denzbl. 1840. # 4to. (6) Fiedler, Dissert, de Laparotomia, Vol. iii.—15 166 CUTTING THROUGH THE PUBIC SYMPHYSIS. different results, and it has happened with this operation, as with many others, that it has been, on the one hand, too much vaunted, as on the other it has been unhesi- tatingly discarded. The indications here given, rest on the experiments and practice of Ansiaux (a), from which it appears that the pubic bones, after the division of their symphysis, are capable of a separation of three inches, without the sacro-iliac symphysis being torn; that by this separation the outlet acquires an additional extent of ten lines, and that by the entrance of*a part of the child's head into the space between the separated pubic bones, a still further space of five lines is obtained. This proportion may, however, vary in some subjects, which, however, can pre- viously be just as little decided, as can any ossification of the sacro-iliac synchon- drosis. In deciding, however, upon the results of cutting through the pubic sym- physis in the dead subject, it appears to me an important circumstance, whether the experiments have been made sooner or later after death. According to Vrolick's (b) experiments, in consequence of the intrusion of the rump-bone in the parting asunder of the separated pubic bones, the increase of the pelvic space is little, and therefore a large restriction of the cut through the pubic symphysis is necessary. Further experience is still requisite to determine how far this operation is appli- cable in the artificially produced premature labour (c). 1847. The operation is to be performed in the following way:—The patient having been placed on her back on a narrow couch covered with a mattress, the pudenda cleared of hair, and the rectum and bladder, in the latter of which the catheter is to remain, emptied, a cut is to be made at the part immediately corresponding to the pubic symphysis, beginning half an inch above the upper edge of the share-bone, and carried down to the clitoris, without wounding it. In the direction of this wound every thing is to be cut through, down to the cartilage. An assistant now presses the bladder aside with the catheter, and the operator introduces a button-ended curved strong bistoury at the lower edge of the pubic symphysis, and thrusting it along the hind surface, divides the symphysis from within outwards. Any bleeding must be stanched by pressure or ligature. If the symphysis be ossified, a little straight button-ended thin saw is to be ap- plied on its upper edge, and division made with some short strokes, during which the assistant draws the soft parts as much aside as possible. 1848. The share-bones now in general separate from each other, which the assistants holding the thighs, allow to take place but very slowly, and the labour proceeds by the natural powers, or is completed by artificial aid. If the bones do not part from each other, the thighs must be slowly separated, till the space between the divided bones has acquired two, two and a half, to three inches extent. 1849. After delivery, the bones are to be brought together, as closely as possible, in doing which special caution must be had that no soft parts be between them. The wound is united with sticking plaster, covered with lint and a compress, and the pelvis supported by a close-fitting girdle applied around it. 1850. The after-treatment is specially directed by the ensuing symp- (a) Clinique Chirurgicnle, p. 79. Experiments to determine the applicability (6) Versnche iiber das Zurvickweichen des of the Sectio Ossis pubis; in Med. Commun. heiligen Beines sowohl im unverletzten of the Massachusi tts Med. Soc, vol. i. Bos- Becken, als nach der Schaambeintrennung; ton, 1808.—Coujou, C, Essai sur la Syn. in von Siebold's Journal fur Geburtshulfe, chondrotomie pubienne. Paris, lb25. 4to. vol. i. p. 542.—von Wy, Ueber die Ausfuhr- (c) Reisinger, Die kiinstliche Fruhgeburt, barkeit und den Nutzen des Schaamfugen- als ein wichtiges Mittel in der Entbindung- schnittes; in same vol. i. p. 502.—Orne; skunst. Augsburg, 1820. BLOOD SWELLINGS ON THE HEADS OF INFANTS. 167 toms of inflammation. If the bladder or urethra be wounded in this Operation, a catheter must be introduced. If suppuration, fistulous sores, caries, or necrosis occur, their treatment must be according to the usual rules. Inflammation of the sacro-iliac synchondrosis, consequent on the extension and tearing it has suffered, requires antiphlogistic treatment. If collections of pus form, they should be opened early. An imperfect union of the share-bones, by which lameness or halting is produced, ren- ders the continued application of a firmly-enclosing girdle, perfect rest and the use of strengthening baths necessary. B.—COLLECTION OF NATURAL FLUIDS EXTERNAL TO THEIR PROPER CAVITIES AND RECEPTACLES. I.—OF THE BLOOD SWELLINGS ON THE HEADS OF NEWLY- BORN CHILDREN. Levret, in Journal de Medecine, vol. xxxvii. p. 410. 1772. Michaelis; in Loders' Journal fur die Chirurgie, vol. ii. p. 657. Naegele, Erfahrungen und Abhandlungen, u. s. w. p. 245. Klein, Bemerkungen fiber die bisher angenOmmenen Folgen des Sturzes der Kinder auf den Boden bei schnellen Geburten, p. 20. Stuttgart, 1817. Palletta, J. S., Exercitationes pathologicae, cap. x. art. 1, De Abscessu capitis sanguine, p. 123. Mediol., 1820. Zeller, C, Praesid. Naegele, Comment, de Cephalaematomate seu sanguineo cranii tumore recens natorum. Heide, 1822. . Hoere, C. F., De Tumore Cranii recens-natorum sanguineo et externo et interno, annexis observationibus de cranii impressionibus et fissures. Berol., 1824. 4to^; with two plates; in von Siebold's Journal fur Geburtshulfe, Frauenzimmer und Kinderkrankheiten, vol. v. p. 219. [Bushe, G. On Hsematoma of the Head in New-born Children, in N. Y. Med. Chirurg. Bulletin, vol. i., 1831.—g. w. n.] Schcemann, J. F., Dissert, de Tumore Cranii recens-natorum sanguineo. Jena?., 1832. Pigne, Memoire sur les Cephalaematomes; in Journ. Hebdom., vol, xii. p. 46. 1833. Rautenberg, Dissert, de Cephalaematomate seu Tumore Cranii recens-natorum. Gotting., 1833. 8vo. Bartsch, Dissert, de Cephalaematomate recens-natorum. Rostochii, 1833. Geddings, E., Observations on Sanguineous Tumours of the Head, which form spontaneously, sometimes denominated " Cephalaematoma," and " Abscessus Ca- pitis Sanguineus Neonatorum;" in North American Archives. July, 1835. [This very interesting and elaborate monograph has since appeared in the Amer. Journ. of Med. Sciences, vol. 23. 1839.—g. w. n.] Unger, von der blutigen Kopfgeschwulst der Neugebornen; in Beitrage zur Klinik. Leipz., 1833. Burchard, J. A., De Tumore Cranii recens-natorum sanguineo symbolae. Vra- tislav, 1837. 4to. Feist, F. L., Ueber die Kopfgeschwulst der Neugebornen. Mainz, 1839. Chelius; in Heidelb. Med. Annalen, vol. vi. 1851. Upon the heads of newly-born children there are not unfre- quently observed soft, fluctuating, generally painless, circumscribed swell- ings, upon which neither the hair nor the skin is at first affected, and in the interior of which, bet-veen the pericranium and the skull blood is collected. It is usually seated on the parietal bones, more frequently than on the right side; it has, however, been observed sometimes on the back of the head, and on the forehead. It varies in size from that 168 BLOOD SWELLINGS of a hazel nut to that of a hen's egg, and even more. Sometimes, though rarely, however, it spreads over the whole parietal bone, sometimes, though rarely, it spreads over both parietal bones at once; several of these tumours of different size may also exist on different parts of the skull. Immediately after delivery, they are in general little raised and stretched, but they grow more quickly or slowly in the first few days, when the swelling is less distended and pappy, and fluctuates. The skin covering it, which was at first natural, afterwards assumes a shining, grayish, reddish-blue or violet colour, according to its tension and ex- pansion. Some practitioners (Lf/vret, Naegele, Hoere) have observed, by the application of the hand, whilst the swelling is on the increase, a pulsation, or a peculiar hardness (Hf.y, Felder) in them, which, how- ever, neither others nor myself could perceive. When the base of the swelling is pressed with the finger, a firm, somewhat raised edge is felt, so that it seems as if a part of the bone were lost. Naegele's opinion (a) that the blood swelling occurs only on the parietal bone is in opposition to the earlier statements (b) and to the observations of others, (Mombert, Schneeman, Dieffenbach, Burchard,) who have noticed these blood swellings on the occipital and frontal bones. 1852. In its further course, the tumour, if left alone and not immode- rately handled, either diminishes gradually of itself, the blood becoming absorbed, and the pericranium re-applying itself, or, what is more usually the case, if the swelling be of large size, it undergoes a peculiar sort of metamorphosis, which consists in a thickening of the pericranium, and its conversion into bone. The tumour has a peculiar elasticity and parch- ment-like condition, so that when pressed, it is like a thin plate of metal, which after being pressed down, rises again, and has a peculiar crack- ling. The swelling gradually becomes harder, and at last as hard as bone, so that like an exostosis, it becomes firmly attached to the other bones; and then by degrees, in a space of time, between four and twelve months, it shrinks, and at last entirely disappears, so that not the slightest trace of it can be discovered. This important metamorphosis, which the blood swelling undergoes, I first (c) described, and pointed out its influence upon the treatment. Although Feist has ascribed this observation to Schmitt (d), and has been followed by Naegele, who has confirmed it, and though Naegele (e) has made no reference to my name on this subject, those, however, who compare my essay of 1828, with those before and since that time, will at least not misplace the plagiarism. I first mentioned (d) that Schmitt had pointed out this metamorphosis ; and nothing more could be said of Schmitt's observation. For according to Goelis, during the treatment of a blood-swelling with caustic, when the tumour becomes as hard as bone, and immoveable, and is not dispersed by the maintenance of suppura- tion and the use of resolvent applications, it must be left alone, and gradually subsides. But Schmitt has asserted the directly contrary and decidedly inap- plicable explanation of this process, " that the portion of bone lying beneath the swelling, which is at first pressed by the weight of the blood is, after the absorption of the blood, again raised up by an oscillation depending on its own elasticity, to which the increased thinning of the bone, perhaps induced by its maceration in the blood, or the more influential act of absorption, seems to give some probability." (n) Feist, above cited, p. 5-7. (d) Salzburgh Med.-Chir. Zeitung., vol. i. (b) Erfabrungen und Abhandlungen, p. p. 32-1. 1819. 247, note.—Zeller, above cited, p. 1. (e) Vklpeau, Traite complet . niensis, vol. i. p. 130. Huun., 1818. (c) Histoire d'une Resection des Cotes et (6) Senac, De la Structure duCoeur, p. 3G5. de la Plevre, p. 10. Paris, If 18.—Nicou, Paris, 1749.—van Swieten, Comment, in Dissert, sur le Danger de la Resection des Aphorismos Bocrhaavii, vol. iv. p. 138.—De- C6tcs, &c. Paris, 181b. sault, CEuvres Chirug., vol. ii. p. 304.— [ 203 ] VII.—OF THE ACCUMULATION OF SEROUS AND PURULENT FLUID IN THE MEDIASTINA. 1908. A collection of water in the anterior mediastinum {Hydrops Mediastini) occurs only in connexion with dropsy of other kinds. More frequently a collection of pus or blood takes place in the mediastinum, in consequence of an external wound which has penetrated the breast-bone, or has injured its surface only after inflammation of the mediastinum, {Pleuritis Stemalis,) or it follows carious destruction of the breast-bone. 1909. The signs of such accumulation are more or less uncertain. If there be symptoms of inflammation of the mediastinum, fever, difficult breathing, pain behind the breast-bone, which generally extends down- wards towards the pit of the stomach, upwards towards the air-tube, and backwards towards the spine; if these symptoms be consequent on external injury, the pain subsides with frequent shiverings; if the patient feel a sensation of weight and pressure behind the breast-bone, if there be oppression and hectic fever, no doubt can remain of the presence of pus behind the breast-bone. If there be carious destruction accompanied with a fistulous opening, the introduction of a probe and the more free escape of pus in particular positions of the patient, besides the above- described symptoms, point out the nature of the disease. If, soon after the breast-bone has been injured by external violence, difficult breathing, pressure and weight behind the breast-bone, and general symptoms of hidden haemorrhage occur, an extravasation of blood has taken place into the medi- astinum. 1910. When the existence of extravasation into the mediastinum is ascertained, its removal is necessary, must not be long delayed, and is effected by perforating the breast-bone (Perforatio Trepannatio.) This operation may be also necessary, in addition to the above-mentioned diseases, for the purpose of removing a dead piece of the breast-bone, or in order to make the reduction of a fracture possible {par. 624.) The part at which the perforation is to be made is directed according to the different objects of the operation: thus, in extravasation, the aperture is to be made opposite it, and where possible at the lowest part; if the ends of a fracture be driven in, upon the still firm remaining part of the bone near the edge that is depressed; and in caries must be so made upon it, that all the diseased part may be removed. 1911. A cut is to be made about an inch and a half in length along the middle line of the breast-bone through the skin, its middle cor- responding with the part to be perforated. The edges of this wound are then drawn asunder by assistants, the periosteum cut through to the extent of the trepan-crown, and then removed with a scraper. The perforation is best made with a trephine, according to the rules laid down in trepan- ning {par. 441.) The perforated bone must be lifted out with an ele- vator, and any connexions with the internal periosteum divided with the knife. But in children, whose breast-bone is still cartilaginous, the perforation can be made with a trocar without a canula. 1912. After the collected fluid has been discharged by proper posture and sopping up with a sponge, a simple dressing must be applied, and a 204 DROPSY OF THE BELLY \ piece of linen spread with mild ointment introduced into the wound fastened with sticking plaster, and bound on with a scapular and chest bandage. The after-treatment depends on the ensuing symptoms of inflammation and suppuration, and is much the same as that directed after the operation of empyema. Upon Trepanning the Breast-bone, see De la Martiniere, Memoire sur l'Operation du Trepan au sternum; in Mem. de l'Acad. de Chirurg., vol. iv. p. 515. Clossius, De perforatione Ossis Pectoris. Tubing., 1795. Fabrice, Diss, de Empyemate Mediastini ejusque curatione, ope Trepani. Al- torf, 1796. VIII.—OF DROPSY IN THE BELLY. (Hydrops Abdominis, Ascites, Lat.; Bauchwassersucht, Germ.; Hydropisie, Ascites, Fr.) Martini, F., Ueber die Art der Abzapfung des Wassers bei der Bauchwasser- sucht; in his chirurgischen Streitschriften, vol. ii. p. 25. Monro, Donald, M. D., An Essay on the Dropsy and its different species. Lon- don, 1765. 8vo. Third Edition. Ackermann, De Paracentesi Abdominis. Jenae, 1787. Spiritus, Dissert, variae rationes Paracentesis Abdominis instituends. Jenae, 1794. Ehrlich's Beobachtungen von der Bauchwassersucht; in his chirurgischen Beobachtungen, vol. i. chap. x. 1913. In dropsy of the belly, the water collects either in the whole cavity of the peritoneum, {General Dropsy,) or in a proper sac, (Encysted Dropsy,) which may be attached either to the peritoneum, or to one of its folds, or it may be formed on some one particular bowel, most com- monly to the ovary {Ovarian Dropsy.) In both cases, if the accumula- tion of water be so great as to produce distention and fluctuation of the belly, and do not yield to the usual remedies, then its removal by tapping {Paracentesis Abdominis, Lat.; Bauchstich, Germ.) is required. 1914. This treatment, indeed, is usually only palliative, as the water soon re-collects ; but it may so far assist the cure as that, after its removal, the remedies which had previously been useless, act efficiently, or if the causes of the dropsy be'got rid of. This will happen so much sooner if the operation be undertaken early, and great re-collection of the water be permitted before it be again drawn off. Although considered merely as a palliative, yet the operation has the advantage over long-continued internal remedies for the purpose of discharging the fluid by the urinary organs, or by the alimentary canal. In encysted dropsy, the operation rarely assists the radical cure, but is more likely to do so if not too long delayed, if there be yet no organic changes in the sac, thickening, scirrhous hardening, and the like. When with dropsy of the belly there is considerable and painful hardening of the bowels, in encysted dropsy, if the collection be very considerable and of longstanding, if the patient's powers have been much sunk thereby, the operation may produce relief for a time, but soon afterwards the patient becomes worse, and usually the fatal termination is hastened. If in encysted dropsy, the position of the sac be such that the operation is not possible without injuring some important part, it is positively forbidden. TAPPING. 205 1915. The spot where tapping is performed, is either the middle of a line, supposed to be stretched from the navel to the upper front iliac spine, especially on the left side, or the point where a line, drawn from the lower edge of the last false rib to the crest of the hip-bone, is crossed by another carried horizontally from the navel to the back. As, however, in ascites, the front wall of the belly is in general most considerably dis- tended, and the strait muscles become much broader, there is not unfre- quently danger in making the puncture at the spot mentioned, of wound- ing either a part of the belly where the muscles are thicker, or the epigastric artery, or one of its branches. On this account the puncture on the white line, two or three inches below the navel, where the walls of the belly are generally thinnest, and no injury in any one artery is to be feared, is preferable (a). [According to Astley Cooper (b) we, at least in England, are indebted to the elder Cline for the adoption, if not the proposal, of tapping in the white line. " His reason for this change was, that in the spreading of the abdominal muscles from the pressure of the water, the epigastric artery is brought into a situation of risk of being wounded by the trocar. This happened to him in tapping a person in St. Thomas's Hospital; florid blood issued through the canula, and the quantity gradually in- creased as the water flowed: as the patient was becoming faint, he withdrew the canula, and closed the wound, but the bleeding continued into the abdomen, and the man died ; upon inspection the epigastric artery was found wounded." (p. 381.)] 1916. When decided hardening of the bowels is felt, another, and indeed the most distinctly fluctuating part is to be chosen: in encysted dropsy that, where the fluctuation is the most strong, care, however, being always taken to avoid the epigastric artery; the navel, if its sur- face be distended like a bladder ; the scrotum, if there be a rupture-sac without gut or omentum; the vagina, when by the pressure of the water, it is protruded. In the latter two cases, care must, however, be taken that a pieee of gut or omentum have not united with the rupture-sac, and that the protrusion of the vagina have not been caused by the bowels, especially by the urinary bladder (c). 1917. The patient is to be put into a half sitting posture, but, if very weak, he must be laid more horizontally on a bed, with the part where the operation is to be performed towards its edge (1). A broad belly bandage, having a four-cornered hole opposite the part to be punctured, is then applied and drawn rather tightly upon the back by assistants. The o'perator holds a trocar of proper thickness, and furnished with a silver canula in his right hand, so that the forefinger stretches along the latter, to about an inch and a half of the point of the trocar, which he pushes in with a rotatory motion and rather obliquely through the walls of the belly, thq thumb of the left hand being placed below the point of puncture. A diminution of the obstruction shows that the trocar has entered sufficiently deep, and then the operator, with the finger of his left hand, fixes and holds fast the canula at the edge of the perforated skin, with the other hand draws out the trocar and allows the water to escape, the assistants generally tightening the belly-bandage in propor- tion, whilst another assistant, with both his hands spread upon the sides of the belly, moderately compresses it. If the quantity of water be large, (a) Cooper Samuel, Dictionary of Practical Surgery, p. 1061, (6) Lectures on Surgery, by Tyrrel, vol. ii. (c) Zang, Operationen, voL iii. p. 295. 18* 206 DROPSY OF THE BELLY ; the mouth of the canula should be frequently closed with the finger, or otherwise an overloading of the blood vessels of the belly and fainting will quickly occur. If the flow of water should be checked by the clogging of the canula, or if any thing lie against its inner end, either a probe must be introduced or a thinner canula, closed at its end but with openings on its side, or the direction of the canula already introduced must be changed, or it must be withdrawn a little. If the operation be performed on an incurable patient, merely for the purpose of relief, and the accumulation of water be very great, only a third, or, at furthest, not more than half should be allowed to escape. When the fluid is so thick that it cannot escape through the canula, it is recommended to introduce a longer trocar, or to enlarge*fhe wound with a knife, or with a piece of tent introduced into the wound (2). A round and tolerably thick trocar is undoubtedly the best instrument for tapping (a). [ (I) Before the operation of tapping is performed it is always advisable to pass a catheter so as to ensure the emptiness and safety of the bladder; and this may also be useful in correcting any mistake in the diagnosis as to the cause of the swelling, since great distention of the bladder, from retention of urine, may so completely stimulate dropsy as to deceive the most wary; at least, since John Hunter was deceived, and tapped a distended bladder for dropsy, if Everard Home tell truly, it well behooves others to be cautious. In women, also, it is especially necessary that no mistake should occur with re- gard to the condition^ of the womb. I knew of an instance in which a pregnant woman would most certainly have had a trocar thrust into the womb by a very eminent surgeon had he not been providentially prevented by the better knowledge of an able practitioner in midwifery. Such dreadful errors have, however, been perpetrated. (2) I do not think a trocar of any kind is the best instrument for tapping. If it were certain that the walls of the belly were always thin, and not tough, it might, perhaps, be so, though I doubt it. But the wall of the belly is very often, nay, very frequently thick, from effusion into the cellular tissue between the skin and muscles, and often tough also, and therefore the trocar requires to be thrust in with more force than is advisable or safe; and it is only surprising that, in the careless way in which tapping is too frequently performed, so little mischief results from it, as too frequently the danger of wounding an intestine by driving a trocar with a plunge into the belly up to the hilt, does not seem to enter the mind of the operator. 1 much prefer the Clines' practice of puncturing the wall of the belly with an abscess- lancet, and then introducing a blunt-ended canula through the wound, notwithstand- ing Samuel Cooper's assertion that " it is superfluous." Immediately the lancet, which should be introduced with its edges vertical, has entered the cavity, the fluid begins to escape, and a blunt canula can be passed without difficulty through the wound. In this way there is no opportunity, or at least as little probability as possible, of injuring an intestine; and the wound, instead of being a bruised one, as it is from the trocar, is a simple clean cut, most favourable for union. I do not recollect to have seen any instance in which it was necessary to stop the escape of the water from the belly on account of the overloading of the vessels or fainting. It is very true that in tapping a dropsy faintness does often occur, but this depends on the want of support which the diaphragm suffers from the withdrawal of the fluid, which had previously thrust it up into the chest and diminished the capacity of the lungs; but when, by the escape of the water from the belly, and consequent relief of the diaphragm from pressure, the lungs and heart have increased room, are capable of receiving, and do receive more blood at the expense of the brain, then faintness ensues. To prevent the diaphragm losing its acquired support, and (a) Upon the different forms of trocar vol. v. p. 611.—Arnemanx, Uebersicht der consult Gusovius, Dissert, qua novem Para- beruhmtesten und gebrSucblichsten Instru- cepteseos instrumentum ofFertnr, Regiomont, mente, p. 132.—Krombholz, Akiologie. 1722; in Haller's Collect. Dissert., Chirurg., TAPPING; AFTER-TREATMENT. 2Q7 to preclude its sudden descent and the consequent fainting, the common practice of a sheet folded, passed round the belly, crossed on the baek, and the two ends con- tinually but gently pulled by assistants, so as to keep the sheet tight and support the remaining contents of the belly against the diaphragm, and not merely to hasten the flow of the water, as generally supposed, should be always employed. If, whilst the water flow off the patient become faint, which is not at all unfre- quent, the tightness of the draw-sheet should be carefully attended to, and wine or brandy given in such quantity as may seem fitting.—j. f. s.] 1918. When the water is emptied, the operator grasps the canula with the fingers of his right hand, closing its mouth at the same time with one finger, whilst with the fingers of the other hand the wall of the belly is held back, and the canula slowly withdrawn by turning it on its axis. The wound is then cleaned, covered with a four-cornered piece of stick- ing plaster, a compress put upon it, and the belly-bandage having been moderately tightened, is made fast. Bleeding may occur after tapping in three ways:—first, by wounding a bowel in pushing in the trocar, blood then escapes mingled with the water; second, by rent of the blood-vessels from overfilling, after the quick removal of the pressure; in this case, towards the end of the operation, the water is tinged with blood; and, third, by wounding the epigastric artery, or one of its branches, the blood then appears after the removal of the canula, or it may be poured into the belly and symptoms of hidden bleeding ensue. In the first two cases proper compression of the belly with cold applications should be employed; in the third attempts should be made to stanch the bleeding, by the introduction of a stiff bougie or a piece of wax taper into the wound, or the wall of the belly should be raised into a fold and compressed for some hours (a). The external branch of the external epigastric artery, generally the largest, is some- times scarcely observable, whilst on the contrary the vessel itself, with its principal branches, passes upwards and inwards, where on tapping, a dangerous bleeding readily ensues if one or other of them be very large (b). [I once, very soon after becoming Assistant Surgeon to St. Thomas's Hospital, had the misfortune to puncture the epigastric artery in tapping a dropsy of the belly. I had tapped this patient on the first occasion in the usual place, on the white line, midway between the pubes and navel. Some weeks after my friend Green tapped him again, and about a month after, a third tapping was performed by me. Fancy- ing that perhaps the scar woujd not readily heal if I tapped in the same place again, I passed the lancet into the white line scarcely half an inch below the old scar, and afterwards the blunt canula. As the water flowed he became very faint, but not more so than I have frequently seen without any ill consequence; and indeed wounding the epigastric artery never crossed my mind, for I felt assured I was far away from it; nor was there any blood with the water, or from the wound after- Wards, to lead to suspicion. Wine and brandy were given, and he was put to bed quickly, He gradually sunk, and died within twelve or fourteen hours. On exami- nation, the belly was found full of blood, I should think four or five pints; and on carefully dissecting the wound and its neighbourhood, the epigastric artery was found to have inclined inwards, very soon after its origin from the iliac, and ran up behind the white line through a large part of its extent, between the pubes and navel, so that it was remarkable the vessel had escaped wound in the first twD operations. From this untoward case I learnt a lesson I have never forgotten, and which I would anxiously impress, to wit, that if tapping be performed safely at' one spot, it should be again and again performed in the same place, if the patient required tapping twenty times. I have known another example very similar to my case, which hap- pened in the private practice of a medical friend, and with the same painful result. I also had another case in which there was considerable difficulty in drawing off the water at all, as I had tapped with a trocar and open canula, and the intestines fell so upon the edge of the tube that I could only give escape to the fluid by introducing a long elastic gum catheter through the canula into the belly. In this case, the (a) Medical Communications, vol. ii. p. (b) Edinburgh Med. and Surg. Journal, 482. vol. iii. p 281. 1822. 208 DROPSY OF THE OVARY | water was much tinged with blood, and, on the removal of the catheter and canula, there was a very free discharge of dark-coloured blood from the wound, which alarmed me much, and was stayed with difficulty by pressure on the sides of the wound. No ill consequences, however, ensued, and some time after I tapped her again without recurrence of this annoyance. Whether correctly or not, I presumed, from the dark colour of the blood, that I had wounded some large veins.—j. f. s. Watson (a) mentions an " instance which he witnessed: clear serum issued for some time through the canula, but at length pure blood, not less than a pint. The patient sunk, and no opportunity was given to investigate the cause of the bleeding. In another strange but well-authenticated case, the almost incredible quantity, twenty- six pints, of blood, flowed out at the orifice made by the trocar, and afterwards sepa- rated into clot and serum. To the wonder of those who saw the incident, the patient recovered from the tapping; and the source of the haemorrhage is still a matter of conjecture." (p. 399.)] 1919. For the first two days after the operation, the patient should be kept quiet, and allowed only a little light food. On the third day the dressings may be replaced, and at the same time rubbing in volatile oint- ments, spirituous fluids, or diluted spirit of ammonia. If there be in- flammation of the diaphragm, or of the bowels, the patient must be treated antiphlogistically, with due attention to the state of the constitution. The inflammation sometimes runs on very speedily to gangrene or to suppu- ration. Colicky pains, if not inflammatory, require aromatic waters, with the addition of some antispasmodic-. If the water re-collect, the opera- tion must be repeated, when fluctuation is again distinct. 1920. The following remarks must be made in reference to the dif- ferent parts at which tapping must be, under peculiar circumstances, {par. 1916,) performed. In puncturing through the navel, the trocar must be thrust through its bladder-like distention and the enlarged navel- ring. Puncture through the scrotum must be performed in the same way as will be directed for hydrocele. In_puncturing through the vagina {b), after having forced the water down still more into the pelvis, by means of >a belly-band, the patient must be laid upon the edge of the bed, her thighs separated, the trocar and canula introduced into the vagina on the forefinger of the left hand, and then thrust into the most fluctuating part. In encysted dropsy, after the swelling has been made very tense by placing a folded towel upon the belly above and below it, the trocar must be introduced at the most fluctuating part. If the water be con- tained in several sacs, it should be attempted, after introducing the trocar into one of them, withdrawing the stilette and drawing off the water, to press the other sacs against the inlying canula, and with the trocar again introduced to open them; or they should be severally punctured. [Among the variety of schemes proposed for the cureNof dropsy in the belly, the ingenious one of Buchanan (c) is worth adverting to, though it was not successful. His object was to ascertain the effect of a communication between the cavity of the peritonaeum and that of the bladder, for which purpose he employed a curved trocar, similar to that commonly used in retention of urine. He first introduced the canula through the urethra, towards the upper and fore part of the bladder, pushing it as far as possible up, to keep the coats of the bladder stretched; and then passing the trocar through it, without difficulty punctured the bladder, and withdrawing it, the water flowed freely. The aperture closed within a fortnight, and the operation was (a) Lectures on the Principles and Prac- the Vagina; in Medical Communications tiee of Physic, vol. ii. vol. i. p. 162. London, 1784. (6) Watson, Henry, A Ca?e of Ascites, in (c) Glasgow Medical Journal, vol. i. p. 195. which the water was drawn off by tapping 1828. diagnosis; puncturing in encysted dropsy. 209 again resorted to, but with the same result. About a fortnight after, the operation was repeated, but with no better success, and was therefore given up.] 1921. Of all dropsies, that of the ovary is the most common. The fluid is of different nature, colour, and consistence, is contained either in one or several sacs, the walls of which are of different thickness. In most cases, this dropsy is accompanied with other degenerations and diseased productions of the ovary, hydatids, steatomatous, and sarcomatous changes, bony, stony, and other concretions. _ The diagnosis of dropsy of the ovary is often difficult vyhen the disten- tion is very great. The following circumstances may direct the prac- titioner: the swelling begins at one particular spot, on one or other side, at which there is often weight or painful feeling for a long time, often after the stoppage of the menses, often after suppression of discharges from the generative organs. With considerable distention, there is also often observed an irregular condition of one or other side of the belly, and, at some parts, a resisting hardness. The state of the general health is usually less disturbed than in ascites. The situation of the vaginal part of the womb is mostly changed, and dragged to one or other side. If the water be collected in several sacs, or there be also other kinds of degeneration, the swelling can be only partially emptied by the puncture, and is then more distinctly felt, and may even be displaced. But if, with ovarian dropsy, there be also ascites, the kind of disease and the contents of the belly can only perhaps be determined after previous tap- ping. Both ovaries are rarely dropsical at once; and the left is more frequently so than the right. According to Blasius (a), ovarian dropsy appears under three forms, as hydrops hydatidosus, saccatus, or cellulosus. In the first form, a number of hydatids are found beneath the serous membrane of the ovary; in the second, the water is collected in a distinct sac beneath the serous membrane; in the third, it is contained in numerous cells within the substance of the ovary. These cells are originally Graafean vesicles, have thick walls, but in which openings are often formed by the pressure of the water, so that several cells communicate together, or even tear on the surface next the cavity of the belly, and discharge the water into it; or, in rare cases, when the Fallopian tube has its open end applied to the ovary, the water escaping by the tearing of the corresponding cell is discharged through the tube into the womb, and escapes by the vagina; in which case, the patient, from time to tinie, loses a pale or discoloured bloody stinking water, by which the swelling of the ovary is at the same time remarkably diminished, and the inconvenience, which it had at first caused, frequently subsides. Any immediate external violence is not necessary to cause this. Blasius has collected examples of this kind, and has distinguished it as hydrops ovarii profiuens. 1922. As puncturing an encysted dropsy, and especially that of the ovary, is only a palliative, various modes of proceeding have been pro- posed for the radical cure. After making the puncture, the canula of the trocar should be left in, to diminish the size of the sac, and then by enlarging the wound to excite adhesive inflammation, or by introducing a flexible tube to keep up the discharge. Ollenroth (6), after first making the usual puncture, thrusts in a round-ended tube through the former, leaves it there some days, empties the fluid several times a day, and applies moderate pressure on the belly. Le Dran (c) made an (a) Commentatio de Hydrope Ovariorura (b) Richter, Anfangsgriide, vol, v. p. 165- profluente. Halce, 1834. 170. (c) Memoire de l'Acad. de Chirurg., vol. ii. p. 431. 210 OVARIAN DISEASE, opening into the sac upon a director introduced through the trocar canula, or immediately upon it, to the extent of four or five inches, held the wound open, and endeavoured by injection or by the introduction of wadding to destroy the sac, or bring about its growing together. Lit- tre (a) effected this by injection. Chopart and Desault (6) opened the sac with caustic, by which it gradually flaked off. Dzondi (c) opened the sac with a cut, passed in a bougie, and separated the loose sac with forceps. King (d), West (e), and Jeaffreson (f), puncture the swell- ing and enlarge the wound, or make a cut on a fold of the wall of the belly, open the peritoneum, carry a ligature through the exposed cyst, empty it'with a puncture, draw the swelling gently forward, put a liga- ture around its stalk, cut off the sac in front of the ligature, and then unite the wound. But when there also exists degeneration of the ovary, or complete steatomatous alteration, in which the former modes oftreat- ment can have no satisfactory result, for the purpose of effecting a radical cure, De la Porte and MoRAND(g-) proposed the extirpation of the diseased ovary; and L'Aumonier {h), Smith (i), Lizars (k), Chrysmar (/), and Quittenbatjm (m), have successfully performed it. The practicability of this operation depends on the usually thin stemmed attachment of the dropsical and otherwise degenerated ovary, which is merely formed by the broad ligament, and has usually no considerable adhesions. The W'all of the belly must be cut into on one side or the other of the while line, according to the seat of the swelling, and to a corresponding length, in whtch the protrusion of the intestines must, as in the Caesarean opera- tion, {par. 1844,) be prevented. The swelling is now carefully separated from whatever attachment it has to the omentum, the peritoneum, and so on, with the fingers or with the knife, and drawn out through the wound; the now apparent thin stem is pierced near the womb with a needle, and tied by means of a double thread, to prevent the ligature slipping off. The stem is then cut through before the ligature, which is brought out at the bottom of the wound, which is to be united after the rules above given for the Caesarean operation. (I) Here also must be noticed Recamier's (n) mode of treatment; the swelling is emptied with a flat trocar, the canula thrust into the blind end of the peritonaeum till it is felt in the vagina, into which it is thrust, and an elastic tube introduced. The result was fatal. [(2) Brown (o) advises a combined constitutional treatment, with tapping and very tight bandaging. He sums up the principal points in the successful treatment of the four cases he has given in the following words:—"I shall divide the treat- ment into constitutional, local, and treatment after tapping. First, constitutional; mercurials administered internally, as alteratives, and externally by friction over the (a) Mem. de l'Acad. des Sciences. 1707, (k) Observations on the Extraction of Dis- p. 502. eased Ovaria, p. 9. Edinburgh, 1825, fol. (b) ffiuvres Chirurgicales, vol. ii. p. 238. {I) In Hopfer, Ueber Exstirpation krank- (c) Beitrage zur Vervollkommung der Heil- hafter Eierstcicke; in Graefe und Walther's kunde, vol. i. Halle, 1816. Journal, vol. xii. p. 60. (d) Lancet, 1836-37, vol. i. p. 586. (m) Quittenbaum, C. F., Solemnia Christi (e) Ibid., 1837-38, vol. i. p. 307. nate precelebranda indicit. Inest Conimen- (/) Transactions of Provincial Medical tatio de Ovarii h\pertrophia et Historia Ex- Association, vol. v. p. 239. 1837. tirpationis Ovarii hypertrophic! et hydropici (g) Mem. de l'Acad. de Chirurgie, vol. ii. prospero cum successu factse. Rostochii, 1 pp. 452, 455. 35. 4fo. (h) Hist, de la Soc. Roy. de Medecine, vol. (n) Revue Medicale, vol. i. p. 19. 1839. v. p. 296. 1782. (o) Cases of Ovarian Dropsy, &c.; in (i) Edinburgh Med. and Surg. Journal, Lancet, 1843-44, vol. i. vol. xviii. p. 532. 1822. OPERATIONS FOR. 211 abdomen, and continued till the gums are slightly yet decidedly affected, and this affection must be continued for some weeks. I lay particular stress upon this point. At the same time diuretics must be given, and after the first week tonics should be combined with them. The food should consist of light animal diet, and should be unstimulating, and the patient should take daily exercise in the air. Second, local treatment; the careful and constant application of tight flannel bandaging, so as to procure considerable pressure over the tumour. When it is proved that the abnormal action has been checked by a positive decrease of the tumour, and a continuation of such decrease, or by a positive non-increase for some weeks, then the cyst should be tapped, and its fluid evacuated. Third, after-treatment; accurate padding (napkins folded in a square form and placed one over the other, so as to form a firm pad) and tight bandaging over the cyst and belly generally, for two or three weeks after tap- ping, and the medicine and friction continued for at least six weeks. I would particularly wish to enforce the importance of the after-treatment, as on that depends very much the success or failure of the case." (p. 181.) Bonfils (a) and Camus (6) recommend, that after puncturing the cyst and with- drawing the water, the canula should be briskly moved in different directions, to bruise and even tear the wound in the walls of the cyst, to prevent the adhesion of its edges, and allow the continual escape of the fluid into the cavity of the perito- naeum, wherexit will be absorbed. Berard, however, thinks that the movements of the instrument rather excite adhesive inflammation and obliteration of the sac. (3) With regard to the advantage derived from tapping an ovarian dropsy, Southam (c) observes, from the analysis of twenty cases which he recites, "that paracentesis, which is generally considered the most effectual palliative, not only affords a very temporary relief, but is by no means unattended with danger. Thus fourteen died within nine months after the first operation, four of whom survived it only a few days. Of the remaining six, two died in eighteen months, and four lived for periods varying from four to nearly nine years. It further appears that paracentesis does not prolong life on an average for more than eighteen months and nineteen days; and that one in five dies of the first operation. Another fact to be gathered from the table is, that the peritonaeum being more prone to inflammatory action in some persons than in others, repeated tappings, instead of proving barriers to extir- pation, show that (other circumstances favourable) there is much less risk of inflam- mation following the operation (of removing the ovary.") (pp. 237, 38.)] The operations now generally performed for the extraction of dropsical or other- wise diseased ovary, are distinguished by the names, the small and the large opera- tion. The'small operation was evidently suggested by Dr. William Hunter (d), who observes:—"If it be proposed, indeed, to make such a wound in the belly as will admit only two fingers or so, and then to tap the bag and draw it out, so as to bring its root or peduncle close to the wound of the belly, that the surgeon may cut it off without introducing his hand, surely in a case otherwise so desperate, it might be advisable to do it, could we beforehand know, that the circumstances would admit of that treatment." (p. 45.) This operation was performed first and with success by Jeaffreson (e) of Fram- lingham, in Suffolk, in 1836, and consisted in "an incision of between ten and twelve lines in the course of the linea alba, midway between the navel and the pubes, and having thus carefully exposed the sac he evacuated by the trocar, about twelve pints of clear serum. During the flow of the serum, a portion of the sac was secured in the gripe of a forceps, to prevent its receding; and he afterwards extracted the sac entire from the cavity of the abdomen, together with another sac containing two ounces of fluid ; indeed the entire ovary, having only to cut through a slight reflec- tion of the peritonaeum and ovarian ligament, which, with the exception of a small portion of the fimbriated extremity of the Fallopian tube are the only natural attach- ments of the ovary to the uterus. But as this part was the medium of vascular supply to the sac, and the vessels on the surface of the sac were unusually large, (a) Gazette Medicale, vol. xi. (d) Remarks on the Cellular Membrane (6) Ibid, vol. xiii. and some of its Diseases, in the History of (c) London Med. Gaz., vol. xxxii. p. 732. an Emphyoemc; in Med. Ob. and Enq 1834. vol.ii. 1762. ** (e) Above cited. 212 LARGE AND SMALL OPERATIONS but he thought right to include it in a ligature previous to returning it into the cavity of the abdomen; the ends of the ligature were cut off close to the knot." (p. 242.) In King's case (a) in which the same operation was performed, it was necessary, '• towards the termination of the extraction, that the opening be enlarged to above three inches; and the obstruction which rendered this requisite, consisted of a solid tumour of about two and a half inches in diameter." (p. 589.) West's was the third case, and he made a cut of two inches long in the linea alba, an inch below the navel. The large operation, as practised by Macdowall of Kentucky, Lizars and Clay, is described by the latter (b) as "a large incision of eighteen or twenty inches in length, or from the ensiform cartilage to the pubes, the ovarian tumour is fully ex- posed, its pedicle and adhesions separated, its vessels secured, and the whole mass removed entire." Walne (c), who follows the same practice, after having made a small opening of an inch and a half in length below the navel, for the purpose of ascertaining the existence of any adhesions which may prevent the propriety of pro- ceeding with the operation, makes a cut of about thirteen inches, leaving a space of three inches from the pit of the stomach, and another an inch and a half from the pubes undivided. He advises, also, that the skin should be marked with lunar caustic across the linea alba, previous to the operation, so as to ensure its proper re- adjustment afterwards. The preliminary treatment consists in abstinence from animal food, and a general antiphlogistic regimen a few days previous to the operation, and Bird strongly re- commends attention to the temperature of the room which was kept at 85° Fahr., and gradually lowered as the patient became convalescent.] 1923. In the critical examination of these various modes of treating encysted dropsy, especially that of the ovarium, the following circum- stances must be borne in mind :—that in all cases in which the disease does not cause great annoyance, any operation is to be considered un- allowable, as frequently the tumour, when it has reached a certain bulk remains stationary, and the patient may live for a long while ; but by the puncture there is only short relief, as the fluid generally re-collects so much the quicker the oftener it is punctured. Sometimes life is much prolonged by repeated tapping, but at other limes fatal inflammation soon comes on. Only in extremely rare instances does the puncture produce a radical cure (d). Fortunate results have indeed been pub- lished of cutting into, injecting the sac, and the like, but in the greater number of cases the result has been unsuccessful (1). The same also applies to extirpation, which, however, if the radical cure be undertaken in degenerated, hypertrophied ovary, when the position and attachments of the swelling are well made out (2), may be considered as ihe opera- tion most to be depended on, and its frequent performance with success does away with Boyer's (e) doubt of the possibility of carrying it into practice. In like manner, in dropsy of the ovary without other de- generation, the operation of opening the wall of the belly with a small cut, drawing out the cyst when emptied, and carefully cutting it off, after putting a ligature around its stem, (King, West, Jeaffreson,) appears preferable to all the other methods proposed for a radical cure, and is supported by the successful cases published, as well as the fact, (a) Above cited. a tabular synopsis of the operations which (b) Cases of Peritoneal Section for the have been recorded, see a paper by Dr. VV. Extirpation of Diseased Ovaria,by the large L. Atlee, in the Araer. Journ. of Med. Sci. incision, &c; in Medical Times, vol. vii. pp. veil. 9. N. S. 1845.—g. w. n.] 43,59, 67, 83, 990, 139,153, 270. (d) Boyer, Traite des Maladies Chirurgi- (c) Removal of a Dropsical Ovarium en- calcs, vol. viii. p. 436. tirely by the large operation. Two pamph- (e) Boybr, Traite des Maladies Chirurgi- lets, 1834. cales, vol. viii. p. 438. [On the removal of Diseased Ovaria, with FOR OVARIAN DISEASE. 213 that such tumours, often even when of great size, contract no adhesions with the peritoneum. On the other hand, it has been objected that although this operation at the first glance appears safest and easiest, as only a small cut is required, and the bowels are subjected to less serious influences, these advantages may be outweighed by the difficulty of drawing the large mass through a small wound so as to reach and tie its stem; whilst the large cut puts the patient in no greater danger of in- flammation than the small one, and has the advantage of getting at the stem with certainty, and of drawing out the tumour without danger. This objection cannot be assented to, as in dropsy of the ovary, unaccom- panied with other degeneration and adhesions, the smaller cut presents indisputable advantages, and therefore the advice is good, always to make first a small cut between the navel and the pubes, so as to ascer- tain if there be any adhesions (a) (3). (1) The puncture of an hydropic ovary through the vagina, cutting into the sac and the various kinds of injection, are followed, according to Callisen, with a fatal result (b). (2) Martini, in one instance, found it impossible to draw out the tumour to its base (c). [ (3) As to the preference of the small over the large operation, or the contrary, much must depend upon the character and size of the diseased ovary, and which can only be decided in the course of the operation. It would seem, however, only reasonable, after making the exploratory cut for the purpose of ascertaining whether the tumour be free from adhesions, first to attempt its removal by the small cut, and afterwards to enlarge it., if necessary. The results of the published cases of both the small and large operation have been, as far as possible, collected by Phillips, Jeaffreson, and up to the present time (July, 1846) by T. Safford Lee, who has recently received the Jacksonian prize for a very able paper " On Tumours of the Uterus and its Appendages," not yet published, but from which he has kindly furnished me with the most perfect account yet obtained ; which, however, is only perfect comparatively, as one of the persons who is believed to have operated on the greatest number of cases in this town at .present has not made known the results of his experience. It appears from Phillips's (d) table, that of the forty-five cases in which the large cut and the removal of the tumour entire was practised, the number of successful cases was only eighteen; whilst of the twenty-five in which as much of the contents of the sac were withdrawn as was possible, and the small cut only used, twelve succeeded. Of the seventy-four cases of the operation for the removal of ovarian tumours which had been published up to October, 1844, and have been collected by Jeaffreson (e), it appears, according to his analysis, that " in thirty-seven cases the tumour was removed, and the patients recovered. In twenty-four cases the operation was fol- lowed by the death of the patient; of these twenty-four fatal cases, the tumour was removed in fourteen, could not be removed on account of adhesions in six, and was found to be other than ovarian tumour in four cases. Thus again in seventy-four cases in which the operation for extraction of ovarian tumour has been undertaken, it has been completed in fifty-one instances, in fourteen, out of which fifty-one, it has been followed by death, and in thirty-seven, by the successful removal of the tumour and the recovery of the patient; whilst out of the seventy-four cases selected, it was found impossible to carry out the intentions of the operator in twenty-three; or in other words the diagnosis was not sufficiently accurate to enable the surgeon to foresee the impracticability of carrying out his intentions. Of these twenty-three cases, (a) Systerna Chirurgia?, vol. ii. p. 71.— Second Series, vol. i. p. 473. 1843. Southam, Vermandois; in Journ.de Medec, par Se- above cited. dillot, vol. xlvii. p, 150. 1813. (d) Med.-Chir, Trans., vol. xxvii. p. 473. (b) Rust's Magazin, vol. xxviii. p. 436. 1844. (c) Key; in Guy's Hospital Reports, (e) London Med. Gazette, vol. xxw. 1814. Vol. hi.—19 214 OPERATIONS FOR OVARIAN DISEASE. thirteen recovered with life to remain in statu quo; and ten died. The cause of failure was impossibility of removing the tumour on account of adhesions in fourteen cases. No tumour was found in three cases; and the tumour proved to be other than ovarian in six instances, (p. 648.) Lee states to me " the actual number of cases in which the peritonaeal cavity has been performed is one hundred and eight (commencing with L'Aumonier's case.) Of these seventy-nine were operated upon by the large incision, twenty-three by the short, and in six cases the length of the incision is unknown. The mortality in these patients is as one death to nearly three recoveries—namely, sixty-nine recovered and thirty-nine died. The operation was not completed in twenty-four out of the one hundred and eight cases, either on account of adhesions or no tumour being found. Of the eighty-four cases where the operation was performed with a fair chance of benefit, fifty'-three recovered and thirty-one died, making as 1 death to 2|£ recoveries. Of the seventy-nine patients operated on by the long incision forty-five recovered and thirty-four died, making the mortality as 1 death to 2%± recoveries. Of the twenty-three operated on by the small incision nineteen recovered and four died, or"l death to 5$ recoveries. From these facts we learn that this operation terminates frequently fatally; that a correct diagnosis is very difficult, and in many instances defective; and that the short incision has been used more successfully than the large." Much difference of opinion still exists as to the propriety of subjecting a female to such imminent danger, as, without doubt, she must incur, in undergoing the ope- ration of the removal of a diseased ovary. In addition to which, much has been said in reference to the malignant character of the disease, which if it were really so, would justly forbid it being meddled with. Southam says, that "having care- fully examined several specimens of dropsical ovaria, he is inclined to believe thai they never present a truly scirrhous character; on the contrary, that they generally consist of simple cysts, or partake of what is called cystic sarcoma (a), for the development of which, the peculiar structure of the ovary appears highly favourable." (p. 238.) The proneness of both ovaries to be diseased has alsO been brought as an objection to the operation. But Southam says :—" I have carefully examined the records of twenty-nine cases of true dropsical-(warm, and found that there were but two in which the opposite ovary presented a decidedly abnormal character. Where, however, the disease was malignant, both were affected in three cases out of four." (p. 240.) It is also held by some, that the patient has a chance of recovery, without the risk of an operation, by the cyst bursting of itself, and, the discharged fluid being absorbed from t;he general cavity of the peritonaeum. Such bursting of the dropsical ovary does now and then occur, but favourable issue is very rare. One case of this kind, in which, after several burstings, and the woman recovered, is related by Bonfils (b). Another occurred recently to Camus (c), in an old woman of eighty-five, who had had an ovarian dropsy for two years and a half. She was then attacked with severe pain in the swelling, attended with extreme lassitude, shivering, and slight fever; on the following day, she had severe pain in the belly, with nausea, vomiting, great restlessness, colic, quick small and hard pulse, and anxious countenance as in peri- tonitis. The shape of the belly was completely altered ; instead of projecting, it was flattened in the centre, but had gained in size what it had lost in prominence. The fluctuation from one side to the other had never been so distinct before. A few days after she began to void large quantities of urine, and in less than a fortnight the existence of fluid in the belly was no longer apparent. Reaccumulation, how- ever, came, on, and the belly became larger than before; but at the end of six months the cyst burst, and the water subsided as before. The belly again filled, and at the end of four months and a half the cyst burst the third time, with less severe symp- toms, and the patient recovered. Dr. Locock informs me, that he has at present under, his care, with Sir Benjamin Brodie, a female about fifty years of age, in whom the ovarian cyst has burst several times. About a year and a half ago, long before any tumour was discovered, she had about once in six weeks an attack of violent abdominal spasms, of the same nature as those which have since clearly been (a)HoDGKiN; in Med.-Chir. Trans., vol. (c) Gazette Medicale, vol. xiii. p. 158. .-xv.-p. 265. 1829, 1845, and Rankin's Half-yearly Abstract of Jjb) Gazette Ms-licdc, vol.xi.p. 746 18:3. the Medical Sciences, vol. ii. p. 151. 1846. OPERATIONS FOR OVARIAN DISEASE. 215 connected with the bursting of the cyst. These attacks became gradually more frequent, latterly once in three weeks. The first discovery of the tumour was about six or seven months ago, a globular elastic tumour of the size of an orange; but pre- vious to this being felt above the pubes, a very distinct elastic tumour was perceived by examination by the vagina. Suddenly spasms came on as before, and the tumour was gone, which led Locock to think it was not an ovarian cyst, as he had pre- viously called it, but only a collection of flatus in the bowel, as great eructations and general abdominal distention always followed the attacks. After several repe- titions of the rise of the tumour gradually, the spasms, and the dispersion, it was noticed that the tumour became larger and larger each attack. Then Brodie detected, after the dispersion, slight fluctuation in the abdominal cavity, which soon disap- peared. The next time it filled, being then the size of a shaddock, they punctured it with a very fine trocar and drew off a few ounces of brown fluid, exactly the same as usually found in ovarian cysts. After this, firm pressure was tried, for a week or two, over the tumour, but she could not bear the pain it produced. Since this, the same alternate filling, bursting, spasms, and disappearance have returned at still shorter intervals, and recently her health has begun to fail. The extreme rarity of these favourable results, however, can scarcely be allowed as argument against the operation. Camus, from the inquiries he was led to in reference to his own case, has obtained some very interesting conclusions: first, that in the rather great number of cases which died immediately, or within a few days after the first bursting, the cyst had, previous to its rupture, contained a purulent fluid, more or less altered, and not the usual serum. Second, that others, after one or more burstings, ascites remained, though it was not proved that the ascites and the dropsy of the ovary had not existed at the same time. Third, that most of the patients, who survived one or two burstings, were cured only for a time, and at last sank under the progressive effects of the encysted dropsy, (p. 158.) Astley Cooper mentions two instances in which the ovarian cyst was burst by accident; in the one, the patient was thrown out of a one-horse chaise, and the dis- ease seemed to have been cured, but it returned seven years after, and sire was obliged to be tapped ; the other patient fell out of bed on the corner of a chair, she afterwards passed large quantities of urine, but the disease returned, (p. 375.) But besides the very rare cure of ovarian dropsy by bursting into the general cavity of the belly, the cyst also very rarely bursts into the fallopian tube, and the water is discharged through the womb. Astley Cooper mentions a case of this kind; and also another in which it burst into the intestinal canal; and though the patient was subject to occasional returns of the disease, she ultimately recovered, (p. 385.) Schmucker (a) also says, that in one case, after the sixteenth tapping, the ovary became suddenly extremely painful in one night, and was followed by the discharge of a large quantity of very stinking ichorous matter through the womb, which con- tinued for some days, and then ceased, (p. 196.) Astley Cooper relates a remarkable instance, in which the navel ulcerated, and large quantities of water were discharged for a considerable time, but ultimately closed, and the disease did not return, (p. 384.) Similar to this, though the open- ing was artificial, is the case of a female of forty-three years of age, who was tapped for ovarian dropsy by my friend Sutton, of Greenwich, in 1821, and three or four times after; on each occasion some hair passed through the canula, and at the last operation, he determined to lengthen the cut downwards, so as to empty all the hair, which he effected. A portion of bougie was kept in by his direction for some months, when the discharge ceased; but the lady fearing the fluid might re-collect, continued the bougie in the wound till her death, of apoplexy, in 1841. In concluding this important subject, it will not be improper to give.the opinions of two able practitioners against and in favour of this operation, about which there is Still so much difficulty in deciding. Ashwell (6) observes:—" If the operation is to become established, of which I have the strongest doubt, it must be confined to examples of the malady where tap- ping has been already so often performed as to preclude, from the experience of similar cases, any idea that it can ever be dispensed with; and where we are con- (a) Chirurg. Wahmehm., vol. ii. \b) Practical Treatise on the Diseases peculiar to Women, 1844. 8vo. 216 DROPSY OF THE WOMB. fident that great suffering must lead to early death. Perhaps this may be regarded as too limited a view of the value of extirpation, but it is, I think, the correct one. In such cases, if the diagnosis excludes the belief that there are serious adhesions, or malignant and solid growths complicating the tumour, and, if the patient strongly desires it, the operation is defensible. In all other examples, it can only rest on the patient's own views of her future prospects, and on a calculation of chances. She might live many years, and without much suffering; she may die in a few years, after great suffering; she determines, therefore, being courageous, and probably strongly urged by her surgeon to run the risk of immediate death, for the hope of immediate and radical cure. Whether she has done wisely to submit to such a hazard, a suc- cessful operation can scarcely prove; that she has happily secured her safety, through eminent peril, such an operation does prove." -(p. 648.) On the other hand, Southam, (a) says :—" The operation is perfectly justifiable when the patient's sufferings are such as to make her life a burden to her; when the symptoms of structural lesion of any important organs are absent; and when the con- stitution is suffering merely from functional derangement consequent upon pressure of the tumour on the neighbouring parts. On the contrary, it ought not to be at- tempted when the well-known characteristics of malignant action are present; when the tumour is solid, uneven, and has been of rapid growth; when the glands in the vicinity are enlarged, and hard knots can be felt in different parts of the abdomen, or when there is distinct evidence of other organs being similarly implicated. Still less should it be undertaken until the surgeon, by varied and repeated examinations, is convinced of the existence of the disease. Nor must the rules, which direct us as to the propriety of operating in other diseases, respecting the condition of the sexual organs, and the fitness of-the patient's constitution to undergo so severe an operation be overlooked." (p. 211.) The number of times which a patient may bear tapping is almost incredible; three, four, and five times are by no means unfrequent. ' Schmucker (b) mentions a woman of forty-five, on whom he operated twenty-nine times in four years; Ford (c) forty-one times in four-and-half years; Schmucker (d) on ano'ther woman, sixty years old, fifty-two times in four years. Mead (e) sixty- five times in sixty-seven months; Callisen (/) one hundred times; in Dartford churchyard "lies the body of Ann Mumford, &c. Her death was occasioned by a dropsy, for which, in the space of three years and ten months she was tapped one hundred and fifty-five times. She died 14th May, 1778, in the 23d year of her age" (g). But Bezard's (h) case exceeds all, a woman who, he says was tapped six hundred and sixty-five times in the course of thirteen years. Whether these cases were ascites or encysted generally, is not mentioned. The quantity of water drawn off, varies of course according to the size of accumulation ; and whether the tapping be repeated frequently, and before the belly has recovered its former size. In the se- cond case, recited above from Schmucker, the quantity had been reduced to five pints; and in the greater number of these operations, three or four quarts only was the quantity withdrawn. Astley Cooper says:—"The smallest quantity he had removed was eight quarts, and the largest twelve gallons and a pint, from an ovarian dropsy, the cyst of which is now in St. Thomas's Museum." Stoerck took away twelve gallons and a half. " The proportion averages," says Astley Cooper, " from twenty-five to thirty-two pints," (p. 374,) and this upon the whole, I believe, a fair estimate. Besides the writers already mentioned, the following may also be consulted in re- ference to puncture and removal of the ovary :— Sacchi, Memoria sull' Idrope delle Ovarie e sulla loco estirpaaione; in Omodei, Annali universali di Medicina, vol. lxiii. p, 257. 1832. Chelius ; in Heidelberg. Annalen, vol. i. Hevin.; in same. [Dohlhoff (i) operated successfully by the large ineision on a large tumour, (a) Above cited. , (/) Syst. Chirursr. Hodiern, vol. ii. p. 55. (b) Above cited, vol. ii. p. 202. (g) A. Cooper's Leciures, vol. ii. p. 374. (c) Medical Communications, vol. ii. p. (h) Bullet de la Soc. Med. d'Emulation, 123. vol. ii. p. 495. 1815. (d) Above cited, p. 187. (i) Caspar's Wochenscbrift, vol. i. p. 513. (e) Medical Works, p. 394. Dublin, 1833. 1767. DROPSY OF THE WOMB; OPERATION. 217 which turned out to be a cyst, containing nine and a half pints of purulent fluid, so closely connected with the under surface and thin edge of the liver and the intestines, that its removal could not be attempted. Having discharged the pus, he filled it with charpie, and subsequently stimulated it with ung. elemi and injections of liq. hydr. mtr., and added Peruvian balsam and tincture of myrrh to the ointment. At the end of two months the discharge had nearly ceased, and she shortly after re- turned to her occupation of midwife.] 1924. If dropsy of the belly accompany pregnancy, either at the onset or during the middle of its course, very considerable uneasiness is pro- duced by the great distention of the belly, by the great swelling of the lower limbs, and by the pressure which the bowels suffer ; breathing is much interfered with, and at last death-like agony, and danger of suffo- cation ensue. 1925. If pregnancy be connected with acute ascites, the regular form of the fundus and body of the womb cannot be distinguished by the touch, specially on account of the enormous distention and projection of the hypochondria caused by the quantity of fluid driven up towards the diaphragm between the fundus and back of the womb and the bowels. The urine is scanty, and the perspiration ceases. In examining the dropsy of the belly, a fluctuation of water is felt, indistinct in the hypogastrion and on the sides, but perceptible and distinct enough in the hypochondria, decidedly so and vibrating in the left hypochondrion between the upper and outer edge of the m. rectus abdominis, and the edge of the false ribs. 1926. This place appears to be most fitting for the performance of paracentesis, without running the danger of wounding the womb or the intestines (a). It is less proper to make the puncture at the usual place, whilst an assistant with both hands presses the womb towards the spine, thus forming a thick fold of skin, which is either perforated with the trocar {b)t or previously opened with a cut made through the wall of the belly (c). 1927. A collection of Water in the cavity of the Womb (Hydrops Uteri, Hydrometra) may exist in that organ when it is either unimpregnated or impregnated. In the former case it comes on with painful feelings about the pudenda, numbness of the feet, irregular menstruation and whites, a cold swelling in the region of the womb, spreading also over the lower part of the belly, in which, on careful examination, a fluctuating move- ment can be perceived. The patient has a feeling of cold over the whole extent of the womb, of its dropping to one side, and when she lies down. If the swelling be in itself very large, there is pain, indigestion, qualm- ishness, vomiting, frequent flatulence, colic, costiveness,. difficulty in making water, retention of urine, at last great wasting and hectic fever. Sometimes the water is discharged by the vagina from time to time, ac- companied with agony and labour-like pains. This discharge is not un- frequently periodical. The signs of distinction between this; kind of dropsy and pregnancy are, the en- largement of the tumour without regularity; its cold, fluctuating feel; the mouth of (a) Scaiipa Menoria sulla gravidanza sus. (6) Visseuk, On Tapping during Preg- seguita da Ascite, ed ossesvazioni pratiche n.ancy; in London Medical and Physical su i avantaggi della nouva maniera d'usare Journal, vol. vii. p. 40. 1802. la paracentesi dell'addomine in simili casi. (c) Bonn, Ueber die Harnverhaltun? n 31 Trevisio, 1817. 8vo. *'1' 19* 218 TYMPANITIS. the womb is thin, tense, and contracted, and does not rise after the third month; its occurrence in girls not arrived at puberty, or in old women, who throughout their whole life have been unfruitful; the breasts are generally withered and contracted, though the contrary is also observed. The absence of the child's motions and of the audible beating of the heart; and, in some cases, the existence of the disease for more than nine months confirms the diagnosis. 1928. In dropsy of the pregnant womb, which may be accompanied with ascites, the belly soon acquires a regular distention as at the end of pregnancy, on striking the belly nothing more is felt than a slight, deep, dull fluctuation ; the quick distention of the womb, the bowels violently thrust up against the diaphragm, in consequence of which there is difficulty of breathing, and even danger of suffocation ; the feet gene- rally swell. A considerable -quantity of water is not unfrequently passed, from time to time, often periodically by the vagina, with symp- toms of threatening abortion. The birth, however, usually occurs at the due time, and after the discharge of the proper waters. The seat of this dropsical accumulation is either between the womb and the foetal mem- branes, between the chorion and amnion, often probably in a proper sac; or there may be a very considerable collection of the liquor amnii. The placenta also may be affected with hydatids during pregnancy. An hydatidous degeneration of the ovum may even produce an accumulation of water in the womb, and^render the diagnosis extremely difficult (o). 1929. The causes of dropsy of the unimpregnated womb are, closing of the mouth of the womb by spasm, its stopping up or growing together, and a diseased condition of the secretion of its inner surface. The re- moval of the water is effected either by the use of the remedies specially employed for dropsy, which act upon the kidnies, the alimentary canal, and the absorbing vessels; or if the mouth of the womb be closed, by warm or steam baths, softening injections, or by the introduction of a female catheter into the mouth of the womb when it is stopped up with plugs of lymph, and the like. If there be adhesion of the mouth of the womb, the above-mentioned remedies are useless; if the symptoms be severe, as when dropsy of the womb accompanies pregnancy, danger of suffocation, and the like, paracentesis uteri is required. 1930. This operation, when the mouth of the womb is closed, is per- formed as already described, {par. 1823,) or between the navel and the pubes, the bladder having been previously emptied and a belly-band ap- plied ; or above the vaginal portion of the womb, in the fluctuating part of the tumour, with a trocar (6). 1931. In distention of the alimentary canal with air, {Tympanitis,) the operation of paracentesis has been proposed by some surgeons, if the ailment be idiopathic and not a symptom of any other disease, if it have existed three or four days, have withstood all remedies, and the patient be exceedingly restless and distressed; the pulse strong and quick, not small and soft; and there be general heat over the whole body unaccom- (a) Sacrpa, above cited.—Cruvelhier, (6) Scarpa, above cited.—Devilliers ; in Essaies sur l'Anatomie pathclogique en ge- Journal de Medecine, par Sedillot, vol. xliii. neral, vol. i. p. 280. Paris, 1816.—Geril, 1812. # (Praeside Naegele,) Dissert, de Hydorrhoea Uteri gravidi. Heidelb., 1821. HYDROCELE. 219 panied with coldness of the limbs. Other practitioners have decidedly opposed such treatment. In performing the operation a long thin trocar with a canula perforated on the sides, is thrust into the middle of a line drawn on the left side from the front end of the second upper false rib to the front iliac spine, to the depth of four or five inches, which directly opens the colon de- scendens. The trocar is then withdrawn, whilst the canula is held in, and the air contained in the bowel escapes, after which the tube is to be removed as already directed. The patient should take but the smallest quantity of drink, indeed only a little iced almond milk, and his thirst quenched with a slice of Seville orange, sugared, and kept in his mouth, or with a cool rather than a lukewarm bath. If there be no subsequent discharge from the bowel, purgative, and afterwards nourishing clysters may be given; and to relieve the loss of tone which the intestine for some time suffers, cold applications and swallowing small pieces of ice may be ordered, (c). IX.—OF HYDROCELE. (Hydrocele, Lat.; Wasserbruch, Germ.; Hydrocele, Fr.) Heister, L., De Hydrocele. Helmst., 1744; in Halleri Diss. Chir., vol. iii. No. 76. Douglas, John, A Treatise on the Hydrocele. London, 1755. Else, Joseph, An Essay on the Cure of the Hydrocele of the Tunica Vaginalis Testis. London, 1776. 8vo. Third Edition. Bonhoeer, De Hydrocele. Argent., 1777. Warner, Joseph, An Account of the Testicles, their Coverings and Diseases. London, 1779. 8vo. Second Edition. Dease, William, Observations on the Hydrocele. Dublin, 1782. Pott, Percival, A Treatise on the Hydrocele, or Watery Rupture, &c.; in his Chirurgical Works, vol. ii. p. 191. Edition 1783. - Murray, A., In Hydroceles curationem Meletemata. Upsalse, 1785. Delonnes, Imb., Traite de l'Hydrocele; cure radicale de cette maladie, &e. Paris, 1785. 8vo. Dussaussoy, And. Cl., Cure Radicale de l'Hydrocele par le caustique. Paris, 1787. 8vo. Keate, Thomas, Cases of Hydrocele ; with observations on a peculiar method of treating that disease, &c. London, 1788. 8vo. Bell, Benj., A Treatise on the Hydrocele, &c. Edinburgh, 1794. 8vo. Earle, Sir James, A Treatise on Hydrocele, &c. London, 1796. Second Edit. Farre, J. R., M.D., Cases of Hydrocele; in Medical Records and Researches, p. 182. London, 1798. Cooper, Sir Astley, Observations on the Structure and Diseases of the Testis. London, 1830. 4to. Benedict, Bemerkungen iiber Hydrocele, &c. Leipzig, 1831. Brodie, Benj., Clinical Remarks on Hydrocele; in London Medical Gazette, vol. xiii. pp. 89, 136. 1834. Dupuytren, Le Baron, De l'Hydrocele et de ses principales varietes; in his Lecons Orales, vol. iv. p. 433, Art. 4. Paris, 1834. 8vo. Curling, T. B., A Practical Treatise on the Diseases of the Testis, &c, p. 119. London, 1843. 8vo. Bertrandi, Memoire sur l'Hydrocele; in Mem. de l'Acad. de Chirurgie, vol iii p. 84. (a) Combalusier, F. P., Pneumotopathologie. Paris, 1747.—De Marchi; in Brerer Giornale, 1813.—Levrat; in Nouvelle Bibliotheque Medicale. 1823.—Zang, Onerationen' vol. iii. pp. 290, 291, 317. * 220 HYDROCELE J Sabatier, Recherches historiques sur la Cure radicale de l'Hydrocele ; in Mem. de l'Acad. de Chir., vol. v. p. 670. Loder, Ueber den Wasserbruch; in Med.-Chir. Bemerk., vol. i. ch. vii. Heden's Neue Bemerkungen und Erfahrungen, vols. ii. and iii. Richter, Vom Wasserbruche; in Med. und Chirurg. Bemerk., vol. i. ch. vii. Larrey, Memoire sur l'Hydrocele; in Mem. de Chirurg. Milit., vol. viii. p. 409. Paris. 8vo. Blandin, Art. Hydrocele; in Diet, de Medecine et Chirurgie Pratiques, vol. x. p. 108. [Smith, N., In Surgical Memoirs. Baltimore, 1832.—g. w. n.] 1932. Hydrocele is a collection of watery fluids in the tunics of the scrotum, or of those of the testicle; it therefore varies according as the water is collected in the cellular tissue of the scrotum, in the vaginal tunic of the testicle, or in that of the spermatic cord. The latter two are, however, in general alone considered as hydrocele, and the former as oedema. 1933. The collection of water in the cellular tissue of the scrotum forms a soft swelling, which retains the impress of the finger, and when it enlarges, becomes tense and firm, unfolds the wrinkles of the scrotum, spreads on to the penis and covers it, and by the swelling of the prepuce, the discharge of the urine is often prevented. Inflammation, suppura- tion, and mortification may result from this swelling. 1934. This disease is either symptomatic and connected with general dropsy and the like, or arises from pressure on the lymphatic vessels by an ill-fitting truss, or from accidental tearing of a hydrocele of the vaginal tunic, and in children from pressure during the birth, and irritation of the scrotum by the urine. The cure depends on the removal of these causes and the use of means specially fitted to oedema. 1935. The collection of water in the vaginal tunic of the testicle, True Hydrocele {Hydrocele tunice vaginalis testis) is always produced slowly, as a swelling rising gradually from the bottom of the scrotum towards the abdominal ring, at first sometimes accompanied with painful distention, but at other times without any peculiar sensation. The swelling has generally an oval form (1), is elastic, tense, sometimes distinctly fluc- tuating, and the appearance of the skin over it is unaltered; in com- parison with its size it is light; it increases neither on coughing nor on any exertion, and cannot be returned into the belly. The testicle is felt, when the swelling is large, generally on its upper and hind part as a hard part (2); its position, however, may vary. The spermatic cord is felt above the swelling, if it extend not to the abdominal ring. If in the dark a light be placed behind the swelling, it is found to be transparent, if the fluid contained within it be clear, and the vaginal tunic be not thickened. Sometimes when the distention is very great, the vaginal tunic and the cellular tissue upon it and the m. cremaster are thickened, the swelling feels harder, is not transparent, and no fluctuation is felt; the vaginal tunic may be even bony. In long-continued hydrocele the spermatic cord and the testicle are varicose, the testicle sometimes wasted. From pressure on the swelling, as in old bulky ruptures, the vessels of the cord are sometimes separated, and thrust either aside or in front of the swelling. If the swelling be very large, the veins of the scrotum swell, the skin inflames and sometimes ulcerates. CAUSES. 221 [(1) The general form of a hydrocele is pear-shaped, largest at bottom, and nar- rowing regularly upwards; but very often it is more oval, and sometimes even con- tracted in the middle, so as to assume an hour-glass appearance. Care must be taken, however, to ascertain that this hour-glass form is not caused by the existence of two hydroceles, one above the other, of which Astley Cooper mentions one instance, (p. 90,) and Brodie a still more remarkable one, in which "he drew off the water from the lower part, and in doing that emptied the upper part. The pa- tient came to him a year afterwards and said he wished to have the water drawn off again. Brodie observed that the contraction of the hour-glass was narrower, and, on drawing off the water from the lower part, found that the upper one was not emptied, and was consequently forced to puncture that afterwards, so that it was evident what had been originally a partial contraction, in the course of a year had become a complete one." (p. 91.) (2) Astley Cooper says:—"The testis is generally placed two-thirds, of the swelling downwards and at the posterior part of the scrotum; pressure at that part gives the sensation of squeezing the testis." (p. 87.) I think, however, from my own observation, that the testicle is generally situated still nearer the bottom of the swelling than stated even by Cooper. The quantity of water in a hydrocele varies from twelve to sixteen ounces, but I have occasionally drawn off between twenty and thirty. The largest quantity on record is, I believe, that of the celebrated Gibbon the historian, from whom the elder Cline drew off six quarts; and Brodie says that he has " seen a hydrocele hanging down to the patient's knees." (p. 89.) The serum of a hydrocele is generally straw-coloured and transparent, but some- times so dark that the light of a candle held behind a swelling cannot be perceived. I have recently had a case of-this kind, in which the serum was dark greenish-brown, and could not be seen through, though transparent, on account of its colour; the vaginal tunic itself was thickened, the hydrocele being very large and of long stand- ing. Transparency, as a diagnostic mark, must therefore be received with some caution. AstleV Cooper also mentions, that the serum "sometimes contains a quantity of white flaky matter, produced by chronic inflammation," and "when produced under acute inflammation, the fluid is sometimes of a red colour, from a mixture of red particles of the blood." He has also seen "in the fluid of hydrocele, loose bodies, of which there is a specimen in the Museum at St. Thomas's." (p. 92.)] 1936. Hydrocele of the vaginal tunic of the testicle is distinguished from scrotal rupture by the way in which it begins, and by the swelling enlprging neither by cough nor exertion, and from hardening of the tes- ticle, by its elastic, uniform, painless fluctuating character, whilst the hardened testicle is hard, irregular, and painful. Hardening, swelling, and hydrocele of the testicle may exist at the same time {Hydrosarco- cele.) Hydrocele has many resemblances to medullary fungus of the testicle, and sometimes the fluctuation at different parts may at first ren- der the diagnosis difficult. The transparency of the hydrocele, when a light is held behind it in the dark, is in all cases to be considered as its most certain character. [Hydrocele may be accompanied with either scrotal rupture or diseased testicle. The rupture-sac may descend as low as the hydrocele and no further, which is com- monly the case when the two diseases exist, together; but it may also descend be- hind the hydrocele, and the existence of the latter niay not be noticed till strangula- tion of the rupture taking place, it is discovered during the operation. Cases of this kind have been already mentioned in speaking of the varieties of strangulated rup- ture, (par. 1199, note.) The diseased condition of the testicle itself is usually without difficulty made out, though imperfectly, before the operation for tapping the hydrocele is performed; but its nature cannot be easily discovered, and there- fore the surgeon must be guided by circumstances in regard to the steps he must take with it.—j. f. s.] 1937. The causes of hydrocele are in most instances unknown; it 222 hydrocele; Prognosis; arises of its own accord in healthy subjects, and is especially frequent in children and old persons. Its cause often seems to be a slow inflam- mation of the vaginal tunic; frequently it occurs after bruises of the tes- ticle in riding, and the like; sometimes from cold; after inflammation or other affections of the urethra; from wearing ill-fitting trusses, and from syphilis. According to Rochoux! (a), the swelling of the scrotum, consequent on a clap, does not, as generally supposed, depend on inflammation of the testicle, but on a hydro- cele arising from inflammation of the vaginal tunic (a vaginalite, as he calls it.) The grounds of this opinion are, that the testicle, surrounded by a firm, thick, fibrous membrane, cannot swell up to such a degree, in a few days, and sometimes even in a few hours, to double its natural size, and even more; that such swelling of the testicle rarely goes on to suppuration, whilst inflammation of that organ from other causes, commonly has that result; that at the onset there is always fluctuation with this swelling, and that, in some cases, fluctuation is perceptible on examination. Gausseil (b) holds that a turbid, thick, somewhat sanguinolent fluid, corresponding to the size of the swelling, and a thick glutinous matter are found. And Rochoux (c) has shown from the examination of six bodies that it depends almost exclusively on fluid in the vaginal tunic. He believes, that if, in the after-course of the disease, fluctuation be no longer perceptible, it depends on the sensitiveness of the part, which will not bear a close examination, and that, when dispersion begins by the absorption of the thin fluid, the swelling takes on the same character as if depending on swelling of a solid organ. Velpeau (d) considers that there may be an outpouring into the vaginal tunic, but that this is slight, and does not constitute the disease, that the pain of an inflamed testicle is greater than when depending merely on fluid, that no transparency can be observed, and that the examination of the swelling with the fingers shows the epidi- dymis participating in the disease. Blandin (e) holds that the state of the parts differs according to the period at which they are examined ; that at first the inflam- mation descends from the vasa deferentia to the epididymes and the testicles, and a swelling of these arises, but that afterwards, and when the dispersion begins, the effusion is a principal symptom of the disease. Pigne (/) remarks, in opposition to these statements, that in young persons affected with this disease, whose hydroceles have been operated on with setons, in spite of the escape of fluid from both open- ings, a hard, irregular, painful tumour, of the size of a turkey's egg, is produced, which can only depend on swelling of the testicle. To this I would add, that after the operation by incision, the hydrocele, sometimes from the swelling of the testicle itself, most decidedly acquires the size of the swelling previous to the ope- ration. 1938. The prognosis of hydrocele is favourable, and proper treatment effects a cure, if it be simple and without complicatibn; but if there be a hardened testicle, the cure is only possible when the testicle can be brought back to its natural condition, or is removed. If the hydrocele be left to itself, nature alone cannot effect the cure, which however is not infre- quent in children. 1939. The cure of hydrocele is palliative or radical. The former con- sists in drawing off'the water by a puncture with a trocar or lancet; it is required in all those cases, where the radical cure is not proper, in very old persons, when there is also hardening of the testicle, and when the patient will not submit to its extirpation; if there be intestinal rupture, connected with the hydrocele-sac, or with the testicle, in very large col- lections of water, and in those cases where the condition of the testicle (a) Archives generales de Medecine, vol. (c) Acad, de Medec, Seance du Sept. 27, ii. p. 51. 1833! 1836. (b) Archives generales de Medecine, vol. (d) Above cited. xxvii. p. 188. (e) Gazette Medicale, vol. iv. p. 638. 1836. (/) French Translation of this Work. SPONTANEOUS CURE. 223 cannot be previously ascertained. The trocar is, in general, to be pre- ferred to the lancet, for emptying the hydrocele, because the fluid will pass by the canula, and not escape into the cellular tissue of the scrotum. The lancet may be used when there is but little water, and accompany- ing intestinal rupture, or hardening of the testicle, because with it all possible injury may be easily avoided. [Spontaneous cure of hydrocele sometimes, though very rarely, takes place. Brodie relates a case of this kind, in which the patient not liking to submit to the operation, the swelling grew so large, that he was obliged to resort to the " old cle- rical cassock to conceal his infirmity. When, however, he had had the disease for some years, the tumour began to disappear, and ultimately went away entirely, so that he was never troubled with it afterwards." (p. 90.) Astley Cooper mentions another mode of spontaneous cure:—"If an hydrocele be suffered to remain and be- come of large size; if the patient be under the necessity of labour to obtain subsist- ence, inflammation of the tunica vaginalis and scrotum will arise from excessive distention. A slough of the scrotum and tunica vaginalis is produced, and as it separates, the water escapes; a suppurative inflammation succeeds, granulations arise, and the patient in this way receives his cure." (pp. 95, 6.) It seems to me that this is precisely what would have happened in the second case of spontaneous cure related by Brodie; had he not checked the mischief by tapping the hydrocele, and drawing off " some ounces of fluid not like that of hydrocele, but a turbid serum, such as you find effused from inflammation." (p. 90.) Hydroceles are sometimes burst by a blow, but, according to both Cooper and Brodie, the disease is not thereby cured, but after a time reappears, the rent in the tunic having probably healed up.] 1940. The situation of the testicle must be ascertained before punc- turing the hydrocele: it usually lies at the upper and hinder part of the swelling, and the best place for the puncture is the fore and under part. The testicle, however, may be situated elsewhere, it may be connected with the front of the vaginal tunic, in which case, a puncture at another part is most proper. The puncture is always to be made in the middle line of the swelling, because, in old hydroceles especially, the several vessels of the cord are often driven out of their place. According to Richter (a), the swelling is sometimes oblique, or even completely transverse, so that in hydrocele of the left side, the puncture must be made on the right side of the scrotum. In large hydrocele, a narrower part of the swelling sometimes extends upwards, even as high as the ab- dominal ring. Under these circumstances, a part of the canalis tunice vaginalis is distended, and by the puncture of the larger swelling, the water escapes from this diverticulum. In children, in whom the punc- ture is rarely necessary, the testicle generally is lower than in adults, the puncture must therefore be made rather higher than usual. The en- larged blood-vessels of the scrotum must be avoided in making the puncture. 1941. The patient must be placed on a seat, so that the scrotum may hang down loose. The surgeon grasps the swelling at its hind part, and tightens the skin, whilst an assistant places his hand at the upper part of the swelling, and presses the water down. The operator holds a thin trocar in his right hand, and puts the forefinger of the same hand on its canula, to within half or three-quarters of an inch from its point, and then thrusts the trocar in rather obliquely upwards at the place determined. When it is ascertained, by the resistance ceasing, that the trocar has (a) Anfangsgrilnde der Wundarzneik., vol. vi. p. 59. 224 HYDROCELE; TREATMENT penetrated the cavity, the point of the trocar is to be withdrawn, and the canula thrust in deeper into the vaginal tunic. The trocar having been withdrawn, the canula is to be held steadily, so that it do not escape from the vaginal tunic whilst the water passes off. If there be a large collection of fluid, its flow must be often checked by placing the finger on the aperture of the canula, so that the testicle should not be too quickly relieved from pressure. When the emptying is completed, the canula is to be gently withdrawn, whilst the edges of the wound are held together with the finger and thumb of the other hand; and afterwards is to be closed with sticking plaster, and the parts supported in a bag truss. The elder Travers (a) has endeavoured to effect the radical cure of hydrocele with simple punctures. The scrotum is made tense with one hand, the patient being so placed that the light may pass through the swelling, to avoid the veins, or any thickened and adhering part. The punctures are to be made with an acupuncture needle, or what is still better, with a fine trocar, at equal distances, very quickly after each other, so that the tension of the scrotum may be kept up. The principal point in the operation Travers holds to be the trifling discharge of fluid, and the escape of the remainder into the m. cremaster and cellular tissue. On the third, or even on the second day sometimes, the fluid is absorbed, and only when, on ac- count of the smallness of the punctures, but a few drops escape, is the cure delayed beyond a month, or even it does not succeed; but in a large number, the cure is effected. Lewis (b) considers a single puncture more efficacious and less dangerous^ I have never witnessed a cure by these means in very many cases. [I have employed this treatment several times, and like Chelius, have not found it successful. The rapidity with which the absorption of the water emptied into the cellular tissue of the scrotum generally takes place is very remarkable; but the punctures in the vaginal tunic soon heal, and the water quickly re-collects, under which circumstances, I have several times had occasion to' perform the cure by injection. The danger from this treatment, which Lewis dreads, seems to me quite chimerical.—j. f. s.] 1942. If a lancet be used, it must, after the scrotum has been made tense, as already directed, be introduced with its edges above and below, at the appointed place, and the opening enlarged as it is with- drawn. Whilst the water flows, the skin must be sufficiently tight, so that the membranes shall not fall together, and prevent its escape ; but if this happen, a probe must be passed in, and the flow restored. If the hydrocele be accompanied with intestinal rupture, it is most advisable to make a cut an inch long at the bottom of the swelling, to lift up the vaginal tunic with the forceps, and divide it with a bistoury held flat. 1943. If after the puncture the fluid will not pass out, on account of its consistence, or because it is contained in various chambers, either the radical cure by incision must be at once performed or the opening closed with sticking plaster, and the radical cure afterwards undertaken. I have always found the fluid thin, and not contained in different sacs, when the testicle has not been otherwise diseased. But I have not unfrequently found, on the outer surface of the vaginal tunic, a pretty considerable quantity of consistent, gelatinous fluid, collected in the cellular tissue; whilst the fluid in the tunic was of its usual character. Sometimes bodies of various size, externally cartilaginous, but bony within, are found swimming in the fluid. They arise, as I have often noticed in the operation for hydrocele and in dead bodies, from the surface of the testicle and epididymis, overspread the vaginal tunic, are always strung together at their (a) London Medical Gazette, vol. xix. p. (b) Lancet, 1835-36, vol. ii. p. 206. BY PUNCTURE. 225 place of attachment, and at last get loose; or are enclosed in a cyst between the vaginal tunic, and the tunica albuginea, from which, when it is opened, these little bodies escape. 1944. The puncture generally soon closes ; if inflammation occur, cold applications and leeches are requisite ; and if it cause effusion into the cellular tissue of the scrotum, a cut must be made into it. If sup- puration occur, it must also be quickly opened. The emptying of the hydrocele most commonly effects only transient relief, and the fluid re-collects more or less quickly. In rare cases is it followed by a radical cure. If the swelling speedily acquire considerable size after the discharge, blood has been poured out into the vaginal tunic, which must be cut into; and if the spermatic artery be wounded, it must be tied. [Simply puncturing a hydrocele but rarely cures the disease ; "but to give the patient the best prospect of it," Astley Cooper recommends " a strong stimulating lotion to be immediately applied." And he continues:—"Exercise sometimes produces inflammation ;" and instances a person who had a cure after the inflamma- tion set up by travelling all night, after the hydrocele having been tapped the previous morning (p. 98); this, however, was a lucky chance, and should not induce another person to try a like foolish trick; for, in another case, he relates directly after, an elderly gentleman, who had been tapped for hydrocele, died in consequence of the inflammation excited merely by a long walk on the same even- ing, (p. 99.) In old people, simple tapping is the only operation for hydrocele which ought to be performed ; the others are very dangerous, on account of the inflammation which may ensue, and being without power, may run on to gangrene.—j. f. s.] 1945. The radical cure of hydrocele may be managed in two ways; either by increasing the activity of the absorbents, by diminishing the exhalation, and producing contraction of the vaginal tunic, whilst its cavity is preserved, or by exciting such a degree of inflammation as will produce a growing together of the vaginal tunic with the testicle. 1946. The first land of radical cure may be effected by the use of solutions of hydrochlorate of ammonia dissolved in vinegar and spirits of wine, by fumigation with cinnabar, with sugar, with vinegar, by emetics and purgatives, and by repeated blisters and the like applied to the swelling. In adults these remedies are seldom of use, but in children they almost always disperse the hydrocele. Perhaps in grown persons they would be more effectual, if the water had been first drawn off. Kinder Wood {a) found that when the swelling had been opened with a broad lancet, and the water discharged, if a little piece of the vaginal tunic were drawn out with a hook, and cut off with scissors, and simply dressed, only a slight degree of inflammation ensued which restored the exhalents and absorbents to their natural condition and caused a cure without the vaginal tunic growing to the testicle. When this tunic is thickened, such treatment is inapplicable. 1947. The second kind of radical cure of hydrocele is effected, first by incision ; second, by injection ; third, by seton ; fourth, by caustic ; fifth, by the tent; and sixth by cutting away the vaginal tunic. 1948. In the operation by incision, the patient is placed upon a firm table ; an assistant grasps the back of the swelling, and tightens the skin. The operator cuts freely through the skin, or through a fold of it, in the (a) MedicChir. Trans., vol. ix. p. 38. 1818. Vol, hi.—20 226 HYDROCELE ) TREATMENT BY INCISION J mesial line, and to the extent of two-thirds of the swelling (1); if the scrotal artery bleed, it must be tied. The operator then placing the fore- finger of his left hand on the middle of the swelling, thrusts a bistoury with its back upon the volar surface, into the vaginal tunic, and carries the finger in with it, so that when the knife is withdrawn, the finger may completely fill up the hole. The blunt-ended blade of a pair of scissors is now passed on the finger, and the opening in the tunic enlarged up- wards and downwards, care being taken that the testicle do not protrude, and if it should, it must be gently returned. An assistant, with his fingers crooked, seizes the tunic at each angle of the wound, and lifts it up, so that its inner surface is laid open. A thin fold of linen dipped in fresh oil is then laid in the cavity of the tunic between it and the testicle, so that its edge projects in a ring around the cut. The cavity thus formed by the linen is to be filled with lint dipped in oil, and the edges of the wound having been brought together with sticking plaster, the whole is covered with a compress, and put into a suspendor. (1) To render the cure satisfactory and perhaps, indeed, that it may be most com- plete, the cut should not exceed a third, or at the most, half the length of the swelling, as is proved by Ficker's (b) and Scwreger's (c) practice, as well as by my own. 1949. The after-treatment is to be guided by the degree of the ensuing inflammation. If not very severe, it must be borne ; but in the other case, it must be allayed by taking out some of the lint, by warm poultices and antiphlogistic remedies. On the third or fourth day, the dressings are to be changed, but the linen is not to be removed till it is quite sodden with pus. The space between the testicle and vaginal tunic is to be constantly filled with lint, and as it diminishes less lint should be introduced. When the suppuration takes place, collection and burrow- ing of the pus must be prevented. After-bleeding requires that the vessels should be tied, or cold water applied. 1950. If in the operation by incision, the testicle be found hardened, its extirpation must be at once performed. Hydatids on the surface of the testicle, or in the cellular tissue of the scrotum,, must be seized with forceps, and cut off with Cooper's scissors. 1951. In the operation by injection, the puncture must be first made with the trocar, as already directed, and the testicle examined, to ascer- tain'if it be hardened. One part of red wine diluted with two of water, and moderately warmed, is now to be injected tbrough^he canula of the trocar into the vaginal tunic with a syringe, fitting into the canula, till the tunic be completely or almost distended to its previous size. The fluid is generally kept in about five minutes with the finger upon the opening of the canula. The sensitiveness of the patient is to determine the strength of the injection and the length of time it should be retained in the tunic. In irritable persons, or if pain arise after the injection, it must be kept in only half the time. In not sensitive persons, when the hydrocele is old and the tunic thickened, pure wine must sometimes be injected, retained for a longer time, and several times repeated, to produce a sufficient degree of inflammation. In repeating the injection, it must be carefully observed that the canula has not escaped from the (a) Aufsatze und Beobachtungen, vol. i. p. 244. (b) Chirurgische, Versuche, vol. i. p-125. BY INJECTION. 227 tunic. If by moving the outer end of the canula from side to side, its inner end move freely, the injection may be made, but if this be not the case, it must first be put right. When the injection has produced the desired effect, it must be carefully drawn off or pumped out with the sy- ringe so that none remain. The greatest care must be taken, when, after the instrument has been thrust in, and the stilette of the trocar with- drawn, that the canula be sufficiently deep in the tunic there kept un- disturbed, and the skin of the scrotum and vaginal tunic be firmly nipped with the fingers round the canula, or otherwise the tunic will easily slip off" and the injection be made into the cellular tissue of the scro- tum. 1952. After the operation, the puncture is to be covered with sticking plaster, and the scrotum supported with a bag truss. In general, on the next day, redness, pain, and swelling come on ; lukewarm applications are to be then made, or if the inflammation be not very violent, it may be left alone entirely ; but if it be great, antiphlogistic remedies must be em- ployed. 1953. In persons peculiarly sensitive, the mildest injection may be sufficient; thus the injection of the water just drawn off, or blowing air through the canula of the trocar to redistend the scrotum. The air may be left in twelve minutes, then let out, and the skin of the scrotum rubbed against the opening. After some minutes the injection of air must be repeated. A bougie should be left in the little wound, so that, if sufficient inflammation be not excited, the inflation maybe repeated (a). Various fluids have been employed as injections in the operation for hydrocele. Celsus used a solution of saltpetre; Lembert, lime water, with corrosive sublimate; Earle, port wine, with infusion of roses; Jinceer, Medoc wine, with water; Levret, a solution of lunar caustic, or of zulphate of zinc; Boyer, red wine alone or mixed with a little alcohol, or boiled with ro^es: Dupuytren, Rousillon wine boiled with roses and a little spirit of camphor; Velpeau (b) has, after numerous success- ful cases, recommended injections of iodine, one or two drams of the tincture of iodine to an ounce of water; the patient suffers little by this plan, and next day can stand without pain, and go about. Velpeau's successful treatment has been confirmed by others. In eleven hundred and forty-eight cases (c) treated with iodine injections, only three cases failed. In ten, injections with port wine failed. Injections of iodine succeeded in nine cases where previous use of port wine and sulphate of zinc had failed (d). [The injection of tincture of iodine diluted with water, I am convinced, by repeatedly practising it for some years, is the most effectual and least painful to the patient. Velpeau has the credit of introducing the practice, but I am informed by medical friends who have been in India, it has long been practiced there, and, if my recollection be not treacherous, without drawing the injection off again. And this mode 1 have adopted, making use of a very fine trocar and canula, drawing off the water, and injecting an ounce of fluid containing two drams of tincture of iodine and six drams of water, and then immediately withdrawing the canula, to which the wound always clings very tightly, ..as the solution is very astringent. The pa- tient most commonly suffers no pain, or at least a very trifling degree ; and though on the following day the scrotum is a little reddened and rather firm, yet the patient is not thereby prevented moving about with ease and comfort to himself. Indeed, I am informed that as soon as the injection is made the person walks away, and re- quires no further attention. The scrotum, according to my own observation, increases (a) Schreger, Ueber Heilung der Hydro- (c) Proriep'.s N. Notizen, vol. viii. 1836, celc durch Lulteinblasen; in his Cliirur- Nov. gische Versucli., vol. i. p. J3-\ Niirnberg, (d) Oppenheim; in Hamburg. Zeitschr., lall. vol. viii. pt. iv. 18^8.—Fricke; in same. (6) Hydroceles dc la Tunique Vacinale; in his Logons Orales, vol. i. p. 262. 1840. 228 HYDROCELE; a little, and becomes rather more solid for three or four days, and then begins to sub- side, and in the course of a fortnight the eure is completed without confining the pa- tient more than two or three days, rather as precautionary, than that I believe it really necessary. I have employed this treatment in both large and small hydroceles, merelylnjecting the quantity mentioned or a little less; and never either shaking the scrotum about or distending the cyst by repeated injections, and afterwards drawing it off, as Velpeau practises and recommends. I am quite sure that whoever once employs the iodine injeetion as I have mentioned, will not treat a hydrocele for the radical cure by any other means. Hydrocele is sometimes not even at first cured by injection; and this Astlet Cooper seems to think depends on the after treatment; " for," he says, "I some- times fail, and should very often but for great care in the after-treatment, upon which, I think, much depends. I sometimes, when water is reproduced a few days after the operation, tap it to remove the serum, and to produce, by this operation, a larger share of inflammation." (p. 106.) But occasionally the injection cures for a time, and then the disease reappears. Brodie mentions two remarkable instances of this kind, one of which occurred to a patient of Everard Home's, in which the disease recurred after seventeen years; and another, which happened under his own care, in which the disease re- turned after twenty years, the operation by injection having been performed in both cases by Home. Sometimes the inflammation set up by injection is so great as to terminate in suppuration; when this happens, and the existehee of pus is decidedly shown, a free cut into the vaginal tunic should be made, so that the pus may readily flow out; after which all the symptoms of constitutional excitement soon cease. If by accident the injection should be thrown into the cellular tissue of the scrotum in- stead of into the cavity of the hydrocele, no time must be lost, but a free cut made through the skin, so that it may readily escape from the loose cellular tissue, other- wise there will be sloughing, and it may be the patient will loose his life, which has happened.—j. f. s.] 1954. For the introduction of a seton, after the puncture as already directed has been made with the trocar and canula, and the former with- drawn, a long tube is passed deeply through the canula, till it reach the fore and upper part of the scrotum. A long and pointed straight sound, with an eye at its other end armed with several threads, is then thrust through the tube outwards, carrying with it the threads, and then the canula is withdrawn. The ends of the seton-threads are tied loosely together, the wounds covered with sticking plaster, and a bag truss put on. About the tenth or fourteenth day, some of the threads are withdrawn at each dressing, and this is continued till all be taken out. J. Holbrook (a) lets the water escape as usual, then takes up a fold of the skin of the scrotum and of the vaginal tunic, and passes with a common needle a single or double thread from above downwards, which he removes on the third day. Onsenoort (b), with a needle curved and having a handle, passes a ligature through the middle third of the swelling from above downwards, or from below upwards. After (he fluid has completely escaped, the thread is tied tightly. Two days after, the ligature is tightened, and after the cutting through is completed, on about the fourth or fifth day, the wound remains open from the bottom till the cure is perfected. In very large hydroceles he thrusts the needle into the middle of the swelling, carries its point upwards out through the skin, leaves one end of the thread loose, carries the point of the needle back into the cavity of the vaginal tunic, thrusts it through the skin below, and brings the other end of the thread out, and as he draws the needle out leaves the thread double in the middle wound, and cutting it through there, forms two ligatures, each of which he ties. (a) Observations on Hydrocele, etc. Lon- gature ; in Graefe und Walther's Journal, don, 1826*. vol. xiii. p. 628. 1828. (b) Heilung der Hydrocele durch die Li- TREATMENT BY SETON. 229 [My friend Green, from having observed the difficulty of regulating the inflam- mation, in treating hydrocele by injection, the impossibility of determining, at the time of the operation, what the effect will be in respect to the quantity of inflam- mation, and the dangerous results from the injection having been thrown into the cellular tissue of the scrotum, instead of into the vaginal tunic, was led to employ the seton (a), but differently from either of the above-mentioned modes. He thought, "if a seton were carried through the tunica vaginalis, there would be a source of irritation sufficient to produce the required inflammation, and at the same time the opportunity given of regulating its degree, that is, that the seton might be allowed to remain till there were symptoms of such a degree of inflammation as is requisite for the change necessary to be produced in the tunic, and that this being effected, the seton might be withdrawn; and that the extraneous irritant being thus removed, it would have no further effect than was necessary, either for the-change of the sur- face of the membrane, or for the obliteration of the tunic, (pp. 73, 74.) The requi- site degree of inflammation is one which is attended with the ordinary symptoms of that process, that is to say, pain, heat, swelling, some redness, and some constitu- tional affection. There should be, I think, some affection of the pulse, some indi- cation of febrile action in the system, before the seton is withdrawn. As soon as this has been observed the threads may be removed, and I believe that you may then expect you have excited inflammation enough to cure the disease. So that it is not whether the seton has remained in ten, twelve, or twenty hours, for this must be regulated by circumstances, but whether then the requisite degree of inflammation is produced. I should say that twenty hours was about the average time for the seton to remain; but it will vary in different instances." (p. 76.) Green's method consists in drawing off the water, as usual, with a trocar and canula, and when the hydrocele is emptied, the "canula still remaining in, to pass a needle six inches in length, and as thick as a probe, with a trocar point at one, and an eye at the other end, armed with twelve threads of ordinary seton silk, into the canula, and having carried it upwards to perforate the tunica vaginalis and integuments, near the upper and fore part of the swelling, and draw it out at that aperture. The canula is then removed, and the ends of the threads loosely tied together over a space of about two inches," (p. 59,) and these allowed to remain in till the inflammatory symptoms above mentioned make their appearance. I formerly employed this practice a good many times, but one great objection seems to me the close wTatching it requires for some hours, and the difficulty there always is in determining the precise time when the seton threads should be with- drawn; and that often, even with the greatest care, either very severe inflammation would occur, or when enough only was supposed present to effect the cure, that it suddenly subsided, and a second operation was requisite. After using the iodine injection, I never recurred to this plan of treatment, although it was grounded upon better reasons than either of the other modes of using setons seem to have originated in.—j. f. s.] 1955. The use of a tent consists in the introduction, after puncturing the swelling, of a tent of lint, or a piece of bougie, through the opening into the cavity of the vaginal tunic. 1956. Caustic, consisting of a paste made with nitrate of silver and water, is applied in the usual way upon the front of the swelling, and allowed to remain for six or eight hours. When the slough has fallen off, the cauterized part is to be punctured with a lancet, and covered, after the emptying of the swelling is complete, with wadding. According to Hesselbach (b), a plaster full of holes, and spread with powdered nitrate of silver, as thick as a knife, should be applied on the front of the swelling, over which a wad of linen and some sticking plaster should be placed, and the whole fastened with a compress and a bag truss. After eight hours the caustic and the plaster are to be taken off, the scrotum cleansed with water, and some lint spread with digestive ointment, applied to the slough. When this falls off, the vao-inal tunic is laid bare, and being raised, by the pressure of the swelling, like a ball°this, (a) St. Thomas's Hospital Reports. (b) Jahrbucher der philosophisch-medicinischen Gesellichaft zu Wurzberff, vol i 20* 230 hydrocele; treatment by caustic, and cutting rounded part is then cut with the scissors, and the water emptied. The wound is to be eleansed daily with water, or with camomile tea, and bound up with lint. At every dressing, pieces of the tunie separate until the whole has come away. The wound daily diminishes, the suppuration ceases, and the wound closes. 1957. In cutting away the vaginal tunic, the skin of the scrotum, and the vaginal tunic are divided, the latter drawn out of the wound with the fingers, and cut off throughout its whole extent by a cut lengthways. The dressing and after-treatment are the same as in the operation by incision. Boyer (a) recommends cutting through the skin the whole length of the swelling, for the purpose of isolating the vaginal tunic as far as possible opposite the testicle, then to open it, and cat off the flaps. Dupuytren considers it more simple to grasp the swelling, at the upper and back part, with one hand, so as to tighten the skin as much as possible in front, then to cut into the skin, to shell the vaginal tunic out, by pressing from behind forwards, and then to open and cut it off. Textor (b) endeavoured to unite the wound by quick union, as Douglas had previously done. Balling (c) strongly recommends excision : the part to be cut off should be some inches, of a semicircular form, After the operation, moderately cold applications should be employed till a layer of lymph appear on the wound, and the union is to be effected with sticking plaster. [1 apprehend no one would, in the present day, employ either of the latter two very painful and uncalled for modes of practice, which are now mere matters of history.—j. f. s.] 1958. The preference and rejection of the several methods above de- scribed must be decided on the following grounds. It. is not advisable to produce upon the testicle any irritation like that on the vaginal tunic. By incision, all the complications can be most distinctly made out, at the same time any existing intestinal rupture can be properly treated, the in- flammation be more properly excited, and effect a more safe cure. The bleeding which occurs in this operation is easily stanched ; the severe symptoms occurring after it are most commonly the result of bad practice. After the cut, it is in most cases necessary to insert a half unravelled piece of linen between the wounded edges of the vaginal tunic. Injec- tions operate uncertainly, as the irritability of the individual cannot be previously determined ; they act as violently on the testicle as on the scrotum; if a part of the injection be poured into the cellular tissue, which is possible, even with the greatest care and attention, very dangerous symptoms may arise therefrom ; in a diseased state of the testicle, which cannot always be decidedly made out, injections are necessarily hurtful. The superiority of injections, to wit, that by their use the cure follows more quickly, and that the patient does not need to be kept so long quiet, is of no value, as even after injection the cure is often longer protracted than by incision, and with the latter keeping so long quiet is not neces- sary. The same observations apply also to the cure by seton and by tent, except that with them the cure is still less sure. Caustic also acts uncertainly; its operation is slow- and painful: incision is therefore to be considered the most sure. Extirpation is to be confined to those cases only where the vaginal tunic is highly disorganized or bony (d). [I have thought it more convenient to notice the advantages and disadvantages of («) Maladies Chirurgicales, vol. x. p. 209. '(d) Textor, above cited.—Klein; in Hei- (6) Ueber cine neue Art. die Hydrocele zu delb. klinisch. Annal., vol. ii. p. 109.— heilen; in N. Chiron., vol. i. p. 4i6. Spangenberg ; in Graefe und Walther's (c) Heidclb.kfet. Annal., vol. vii. pi 130. Journ., vol. ix. p. 1. AWAY THE VAGINAL TUNIC ; CONGENITAL HYDROCELE. 231 the several modes of treating hydrocele, when describing each method. To these, therefore, the reader is referred back.—j. f. s.] 1959. Congenital hydrocele {Hydrocele congenita) consists in a collec- tion of water in the canal of the vaginal tunic, which remains open either throughout its whole length, or only at certain parts, in consequence of which several kinds of hydrocele are formed: first, the canal is open throughout its whole length, and filled with water; second, the canal is closed above the testicle, and remains open only at the upper part; third, the upper part closes and the water is contained in the lower part, and in the vaginal tunic of the testicle; fourth, the canal is obliterated above and below, and there remains only a bladder-like cavity at one part, which contains water. 1960. If the whole vaginal process of the peritoneum remain open from its orifice in the belly to its bottom, and the water collect in it, a long roundish swelling appears, which reaches from the abdominal ring to the testicle. The testicle is either little, or not at all felt, because it is completely surrounded with water; but, on the contrary, the spermatic cord is distinctly felt along the hind surface of the swelling, though rather more outwards. The possibility of pushing back the fluid, and its return by the abdominal aperture of the vaginal process causes the diminished size or total disappearance of the swelling, in the horizontal posture, or by pressure, and its increase in the upright posture, by exertion, cough- ing, and the like. The subsidence and reappearance of the swelling does not take place with equal readiness in all cases: if, for instance, the upper part of the vaginal canal be somewhat narrowed, a longer con- tinued pressure upon the swelling from below upwards is necessary, in order to force the water back; or it must also be raised somewhat inwards, so as to bring the vaginal process in a right line with the inguinal canal: the water retires slowly, and only slowly returns. The natural cure is in these cases not rare. If the disease continue beyond the first month, it becomes larger; sometimes it attains quickly, sometimes slowly, a considerable size. The end of the first twelvemonth, the third and seventh year, and the period of puberty, have considerable influence on the development and subsidence of this kind of hydrocele. Closely resembling hydrocele of the vaginal process in man, is the congenital hydrocele of women, in which, by the collection of water in the peritoneal sheath of the round ligament, a swelling is formed, which passes through the inguinal canal into the lower part of the labium pudendi, and is at first returnable, but afterwards not so (a). 1961. This hydrocele may have already formed in the foetus, and after- wards become further developed; but it may first arise after birth, as the vaginal canal often remains open for some time. The circumstance of the vaginal process often remaining a long while open, and no water being collected in it, proves that the water does not merely flow from the belly into the vaginal process, but that its collection depends on undue proportion between absorption and secretion on the inner surface of the vaginal canal. This disease is frequent, but in many cases is not ob- served, partially on account of its slight degree, and the child's con- stantly lying on his back, and in part because it subsides of itself. It (a) Sacchi ; in Annali Universal-! de Medicina, vol. lvii. p. 437. 1831. 232 COMPLICATED HYDROCELE ; is not unfrequently accompanied with • protrusion of the intestine or omentum. 1962. The cure depends on getting rid of the water, and closing the vaginal process by the adhesion of its walls. Viguerin endeavours to effect it by pressing back the wrater into the belly, and closing the abdo- minal ring with a truss. Desault, after returning any existing rupture, and carefully closing the abdominal ring by pressure, punctured the swelling, emptied the water, and injected red wine, which after a little time he withdrew, and wrapped the whole scrotum with compresses steeped in red wine, and applied a truss {a). 1963. Although the treatment of congenital hydrocele, with injec- tions, has, in many instances, been successful, it cannot, however, be denied, that it always has a very serious effect on little children, and that dangerous inflammation may ensue. Viguerin's practice is, there- fore, always preferable, and may, perhaps, cause a more certain cure, if the pressure be sufficiently strongly made on the upper part of the vaginal process, and a suspender, moistened with spirits of wine, vinegar, and muriate of ammonia, or any other astringent fluid, be at the same time worn. 1964. If the vaginal process be adherent merely above the testicle, and thence open into the cavity of the belly, a bladder-like swelling is formed by the collection of the water in this open part, which may extend even into the cavity through the abdominal ring. The water can be returned but slowly into the belly. The treatment is the same as in the previons case. 1965. If the abdominal mouth of the vaginal canal be closed to the pillars of the abdominal ring, and the other part remain open, the water collects in that part even to the bottom of the vaginal tunic. In this case the swelling terminates at the ring, and the water cannot be pressed back into the belly. 1966. If the vaginal canal be obliterated above and below, a cyst is formed in the part remaining open by the collection of water, which cyst is connected with the peritoneum, and extends from the abdominal ring to the testicle. After lying on the back the swelling is less tense; but it becomes more full and elastic after long standing. If com- pressed, it recedes a little, but quickly reappears. The spermatic cord may be felt below or behind the swelling. 1967. The treatment of these last two kinds of congenital hydrocele requires, in most cases, only the use of dispersing remedies, by which, in children almost always, their cure is effected. These are rubbing in mercurial ointment, or spirituous fluids; the steam of vinegar; fumiga- tion with mastic, amber, or sugar; lotions of spirits of wine, red wine, the acetated liquor of ammonia, alum dissolved in water, with a little sulphuric acid ; dispersing plasters, and the like. If not thus cured, the water must be emptied by puncture, and the radical cure by injection, or by blowing in air, resorted to. In cystic hydrocele, in children, the discharge of the water is best managed by puncture with the lancet; but in adults, the cyst should be laid bare with a cut, and removed with Cooper's scissors. (a) OBuvres Chirurgicales, vol. ii. p. 441. DIAGNOSIS. 233 The following works may be consulted on Congenital Hydrocele:— Schreger, Neue Darstellungen aus dem Gebiete der Hydrocele; in his Chi- rurgische Versuche, vol. i. p. 1. Wall, C. A., De di versa Hydroceles congenita? nature. Berl., 1820. 1968. When a hydrocele is connected with a rupture, that is, when the sac of a congenital or accidental rupture has its usual contents of collected water and protruded intestine, the hydrocele in general rises up to the pre-existent rupture; the hydrocele is rarely first present,.and the rupture subsequent. In most cases rupture, complicated with hydro- cele, is always accompanied with adhesion, and the hydrocele is the unnatural secretion of the inner surface of the rupture-sac, in consequence of the inflammation which has caused the adhesion. This inflammation may arise from undue pressure of a truss, from catching cold, external violence, and the like. A collection of water soon forms in strangulated rupture. 1969. The symptoms vary according as the hydrocele connected with a rupture is larger or smaller. For example, first, if the protruded intestine be quite full, and close the upper part of the rupture-sac, and the water collect only in the lower space,, as happens when an inguinal rupture is added to a pre-existing congenital hydrocele, or a hydrocele to a congenital rupture, or an omental or intestinal rupture adherent at the neck of the sac is complicated with hydrocele, then the form of the swelling is at first conical, with its base towards the abdominal ring; but, in proportion as the water collects, the upper part of the swelling becomes narrower. If the rupture or the hydrocele be congenital, the swelling extends to the bottom of the scrotum, then it is surrounded with water, and cannot at all or not satisfactorily be distinguished. On the contrary, if the swelling be confined to the testicle, it can be felt at the under hinder part. Second. If the protruded intestine completely enter the rupture-sac, and the water only spread over its surface and the inter- spaces, as in hydrocele accompanying ruptures which are moveable, enlarge easily, are very old, or are attached to the bottom of the rupture- sac, then the swelling enlarges more in breadth than in length, and mostly assumes an oval form. Third. In a congenital rupture, when the upper part of the vaginal canal is narrow, and little extensible, the water may completely fill the whole bag, and merely a small portion of intestine or omentum protrude externally through the abdominal ring, and be sur- rounded with the water. m Fourth. A small intestinal rupture, when accompanying a previously existing hydrocele, may remain in the canal between the internal and external abdominal rings, in which case the rupture is prevented by the stricture of the canal exceeding the bounds just mentioned. 1970. The diagnosis of these different forms of hydrocele, complicated with rupture, is, in many instances, accompanied with great difficulty. The following circumstances, however, lead to it. In the first case, the upper part of the swelling, when intestine is there, is firm, elastic, and hard, but doughy, with an omental rupture; the lower part, which con- tains the water, is yielding by elastic, sometimes even fluctuating. With a reducible rupture, there remains, after its return, a fulness at the bottom of the sac which cannot be produced by a piece of intestine, because it is not attached to the abdominal ring, and when this is the case, the 234 COMPLICATED HYDROCELE ; TREATMENT. water can be driven backwards and forwards. In old and adherent ruptures the diagnosis maybe more difficult, though it can be determined by a close examination, and the case may be distinguished from a growth of the protruded parts, or from an enlargement of the swelling by newly- projected parts. In the second case, examination does not present the simple elasticity of intestinal rupture, nor the regularly distended con- dition of hydrocele, as at the part where the intestine is, it is more rebounding, and the fluctuation scarcely at all decided, and only ob- scurely perceivable at some spots. In this and the previous case, there is this peculiarity, that in long-continued horizontal posture the bulk of the swelling, lessens, as a part of the water, if the neck of the sac be not entirely closed, by the adherence of the rupture itself, returns into the belly; on the contrary, in long-continued standing, the swelling enlarges, by the re-descent of the water. In the third and fourth cases, the diagnosis may indeed be difficult; here, however, the history of the dis- ease, as well as a certain fulness of the inguinal- region, immediately above the external abdominal ring, directs the practitioner, as well as the circumstance, that if the rupture follow a pre-existing hydrocele, instead of the appearance of the fulness in the inguinal region, the water is returned wTith more difficulty into the cavity of the belly, and that it returns freely, when the rupture has entirely, or, for the most part, been reduced by the previous attempts at reduction acting on the region of the abdominal ring. 1971. The treatment of hydrocele accompanied with rupture, is espe- cially directed in reference to the condition of the latter, whether it be moveable or adherent. 1972. With a moveable rupture, a cut an inch in length is first made through the skin,- so as to return the intestine, the exposed rupture-sac is then lifted up with the forceps, and a slight opening made in it with the scissors for the purpose of introducing an injection-tube, through which, the abdominal ring being carefully closed, one of the above-mentioned injections {par. 1951) may be thrown in to excite adhesive inflammation, and with moderate compression, to produce union. After the reduction of the rupture, this may be effected by making a cut and introducing a tent A truss must be worn till the complete adhesion of the sac has been effected, and even longer. Desault (a) first emptied the water by a puncture with a trocar, then whilst the canula was remaining in, replaced the rupture, and injected red wine. 1973. When the rupture is adherent, and the adhesions are firm and considerable, the treatment, with an intestinal rupture, must be merely confined to palliation by puncturing with a lancet, after previously making a cut through the skin, or opening the exposed rupture-sac as in the operation for strangulated rupture, and by the use of a suspendor. Con- genital omental rupture allows an earlier radical cure of hydrocele, as the omentum more readily assumes the process of adhesive inflammation. If, however, the union be slight, which may be determined by the possibility of reducing the greater part of the rupture, the sac must be carefully opened by a cut as in the operation for hydrocele, the adhesions divided, the taxis employed, and then by introducing a tent of lint a sufficient (a) CEuvres Chirurg., vol. ii. p. 441. ENCYSTED HYDROCELE. 235 degree of inflammation excited for the purpose of furthering the adhesion of the rupture-sac (a). [I do not think that under any circumstances a conjoined congenital hydrocele and rupture, or a congenital hydrocele followed by protrusion of intestine, should be meddled with in any way beyond the use of cold astringent washes and the appli- cation of a truss. Injections or the introduction of tents, I should think exceedingly dangerous practice, and on no account to be resorted to.—j. f. s.] 1974. Hydrocele of the general vaginal tunic (Hydrocele tunice vaginalis communis) is either an cedematous swelling in the cellular tissue, which surrounds the spermatic cord, or the water collects in one or more cells of the spermatic cord, or is found in hydatids, {b). 1975. In the first case, the swelling which is along the spermatic cord, at first produces no inconvenience, the scrotum is not altered, except that if it be not wrinkled, it drops lower on one side than the other. The testicle is felt in its natural state. The swelling is broader below than above, seems to diminish by gentle and pushing pressure, though it resumes its appearance wdien the pressure is removed, both when the patient lies down and stands up. If fluctuation be observed, it is only distinct at the bottom, because the water sinks down especially, tears some of the cells, and so forms a larger cavity ; therefore, no considera- ble quantity of water can be drawn off when a puncture is made any where but at the bottom of the swelling. If the base of the tumour be pressed, the water quickly rises up towards the top, and distends it. And if the swelling be within the abdominal ring, it distends it also. When it acquires a certain size, the patient often feels pain and dragging in the loins. The disease may be accompanied with a varicose state of the spermatic cord, and with omental rupture. Its confusion1 with 'the latter of these is very easy, and the following may be remembered as distinguishing characters between them, that the hydrocele of the sper- matic cord has less consistence, and has not so irregular surface as omental rupture; it is also usually broader towards its base, whilst the contrary is the case with omental rupture (c). 1976. So long as the swelling in infiltration of the spermatic cord is small, a suspendor should be worn : when the disease becomes inconve- nient, the swelling must be opened with a cut, without wounding the cord, and lint put into the wound, which is to be cured by granulation. 1977. Hydrocele in one or more cysts (Hydrocele cystica) is mostlv situated in the middle of the spermatic cord. The swelling it produces is very much distended, so that the fluctuation is not always dis- tinguishable, circumscribed, painless, and transparent. It can never be diminished. If it lie near the abdominal ring, it can be often somewhat pushed into it. The testicle and cord are distinctly felt. If the swell- ing enlarge deeply towards the testicle, the latter is felt on its hind part. Children and young persons are more subject to this hydrocele than adults; it is very probable that in most cases this results from a partial opening of the vaginal canal, whilst it is obliterated above and below and losses itself in the cellular tissue, (par. 1966) {d). (a) Schreger, Ueber Erkenntniss und Be- aqueuse des Bourses; in Mem. de Chirurff. handlung der init Hernie complicirten Hy- Militaire, vol. iii. p. 419. drocelen ; above cited, p. 86. (c) Scarpa. (b) Larrey, Observation sur uue Tumeur (d) Scarpa, above cited.—Froriep's Chi- rurg. Kupfertaf., pi. cii. ciii. 236 URTNARY STONE. 1978. In children this swelling is often dispersed by the remedies already mentioned (par. 1967); in adults it is stubborn. If an operation be required, the cyst is to be laid bare by a simple cut through the skin opened, and so much of it removed as can be done without wounding the spermatic cord ; some lint is to be put into the wound, the suppura- tion destroys the rest of the cyst, and the~wound heals by granulation. Fourth Section.—FORMATION OF STONY CONCRETIONS IN THE FLUIDS OF THE BODY. 1979. In the various fluids of the body, especially in the urine, bile, spittle, and. feces, when they are retained, or when their properties are altered by individual constitution, disease, mode of life, influence of climate, or of food, in regard to their quality and quantity, hard, stony concretions may be formed by the union of the several constituents, or by the production of new substances. Sometimes there may be a foreign body around which the constituent parts of the fluids are deposited so as to incrust it. The phenomena which these concretions produce, are different according to their seat, their form, and their quantity. The treatment consists in their solution or removal. At present merely the stony concretions in the urine are to be considered. I.—OF URINARY STONE. Beverovich, J., De Calculo renum et vesicae liber singularis; cum epistolis et consultationibus magnorum virorum. Lugd. Batav., 1638. Tenon Recherches sur la nature des Pierres ou Calculs du Corps humain; in Mem. de l'Acad. des Sciences, 1764, p. 374. Scheele, C. W., Untersuchungen des Blasensteins; in Schwedischen Abhand- lungen, vol. xxxvii. 1776. Austin, William, M. D., On the component parts of the Stone in the Urinary Bladder. London, 1780. Link, H. F., De Analysi Urinae et Origine Calculi. Gotting, 1788. Walter, F. H., Anatomisches -Museum, vol. i. Berlin, 1796; with five plates. Wollaston, W. H., M.D., 0» Gouty and Urinary Concretions; in Phil. Trans., vol. lxxxvii. p. 886. 1797. Pearson, George, M. D., Experiments and Observations to show the com- position and properties of the Urinary Concretions; in Phil. Trans., vol. lxxxviii. p. 15. 1798. Fourcroy, Examen des Experiences et des Observations de M. Pearson; in Annales de Chimie, vol. xxvii. p. 225. Guyton; in same, p. 294. Fourcroy, Observations sur les Calculs urinaires de la Vessie de l'Homme; in Mem. de la Societe Medicale, vol. ii. p. 64. 1799. -----, Des Calculs urinaires de l'Homme ; in his Systeme des Connaissances Chimiques, vol. v. p. 501. Paris, 1801. Fourcroy, Sur le Nombre, la Nature, et les Caracteres distinctifs des differens materiaux qui forment les Calculs, les Bezoards et les diverses Concretions des Animaux; in Annales du.Musee d'Histoire Naturelle, vol. i. p. 93. Paris. Brande, William, On the differences in the structure of Calculi, which arise from their being formed in different parts of the Urinary Passages; and on the effects that are produced on them by the internal use of solvent medicines; in Phil. Trans., vol. xcviii. p. 223. 1808. ORIGIN OF URINARY CONCRETIONS. 237 Wollaston, W. H., M.D., On Cystic Oxide, a new species of Urinary Calculus; in Phil. Trans., vol. c. p. 223. 1810. Marcet, Alexander, M.D., Essay on the Chemical History and Medical Treat- ment of Calculus Disorders. London, 1817. 8vo. Magendie, Recherches physiologiques et medicales sur les Causes, les Symp- tomes et le Traitement de la Gravelle. Paris, 1818. Brugnatelli, L. V., Litologia umana ossia Ricerche chimiche e mediche solle Sostanze Petrose che si formano in diversi parti de corpo umano, soprattuto nella Vesica Urinaria. Opera postuma, public, dal D. G. Brugnatelli. Pavia, 1817. fol. 3 plates. von Walther, P., Ueber die Harnsteine, ihre Entstehung und Classification; in Journal fur Chirurgie und Augenheilkunde. vol. i. p. 190—p. 387. Henry, William, M.D., On Urinary and other Morbid Concretions; in Med.- Chir. Trans., vol. x. p. 128. 1819. Prout, Wtilliam, M.D., An Inquiry into the Nature and Treatment of Gravel, Calculus, and other diseases connected with a deranged operation of the Urinary Organs. London, 1818. Wetzlar, G., Beitrage zur Kenntniss des menschlichen Harnes und die Entste- hung der Harnsteine. Mit einer Vorrede und einigen Anmerkungen begleitet von F. Wurzer. Frankfort, 1821. 8vo. Laugier, Sur les Concretions qui se forment dans le Corps. Paris, 1825. Brodie, Sir B. C, Lectures on the Diseases of the Urinary Organs. London, 1842. Third Edition. 8vo. Martin, E. A., De Lithogenesi, prasertim urinaria. Jenae, 1838. Crosse, J. G., A Treatise on the Formation, Constituents, and Extraction of the Urinary Calculus. London, 1835. 4to. Civiale, Traite de l'Affection calculeuse, etc. Paris, 1838; with five plates. .-, Translated into German by Hollstein as, Ueber die medicinische Be handlung und Verhiitung des Steines und Grieses, nebst einer Abhandl. iiber die Steine aus Cystin; mit Bemerk., u. s. w. Berlin, 1820. Willis, Robert, M.D., Urinary Diseases and their Treatment. London, 1838. 8vo. Jones, H. Bence, On Gravel, Calculus, and Gout; chiefly an application of Pro- fessor Liebig's Physiology to the prevention and cure of these diseases. London, 1842. 8vo. Taylor, Thomas, A Descriptive and Illustrated Catalogue of the Calculi and other Animal Concretions contained in the Museum of the Royal College of Surgeons in London. London, 1845. -4to. 1980. The deposits from the urine are either powdery or crystalline, gravel, or hard large concretion, stones, which are formed by the union of these sediments. [For the accompanying notes on the chemical part of this subject marked T. T., I have to thank my friend Thomas Taylor.—j. f. s.] 1981. From the earliest times various opinions have been advanced as to the manner and way in which the formation of these concretions take place, which, however, has only been placed on a sure base by the pro- gress of chemistry., and by the careful examination of these concretions, especially by Scheele, Wollaston, Fourcroy, Vauquelin, Brande, Marcet, Prout, Magendie, Fuchs, Liebig, Woehler, Willis, Tay- lor, and others. Passing over the old opinions, those theories only which have of late years been advanced in reference to the formation of stone will be here given. Wurzer (a) has collected the most valuable notions of the old practitioners and naturalists on this subject. So also Martin (b). 1982. Magendie, who treats specially of uric acid concretions imagines (a) Programma de Analysi chemica Calculi Renalis Equini. Marburg, 1813. (b) Above cited. Vol. iii.—21 238 ORIGIN OF that the causes of gravel and stones of this kind depend on an absolutely increased quantity of uric acid, on a diminished quantity of the urine with the like quantity of uric acid, and on the diminished temperature of tfte urine, in consequence of which the uric acid is deposited either in the form of gravel, or, being united by some connecting matter, forms the larger concretions. The quantity of uric acid is increased by the use of food abounding with azote, flesh meat, strong wine, liquors, want of ex- ercise, and the like. The quantity of urine diminishes whilst the quan- tity of uric acid still remains the same, in violent sweating. And the temperature of the urine diminishes in advanced age, on which account gravel is then of common appearance. The above cases are also espe- cially favourable to gout; and, therefore, between gout and stone there is a close alternation. 1983. von Walther assumes, besides the excessive production of uric acid, a change in its quality, at least in reference to its degree of oxida- tion, and a more or less copious secretion of a connecting gluten.. These three circumstances arise from a vital influence of the urinary organs on the fluids contained in them ; and the activity inducing lithogenesis, con- sists, if not in an inflammation of the mucous membrane of threse parts, (as believed by the English physician, W. Austin,) at least in a state analogous to it. Hence originates a more copious production of the connecting substance which takes up the precipitated particles of the strongly oxidized uric acid, and thus gradually forms the nucleus of the stone. Without this connecting matter, sand and gravel alone are pro- duced. The presence of this gluten, especially prevents the crystalliza- tion of the constituent parts of the stone and the ammoniaco-magnesian phosphate alone is most frequently crystallized in stones. Lithogenesis is to be" considered as a medium between chemical crystallization and organic growth, but it has always the greater disposition towards the latter. Stones are characterized by their organic structure; and their process of formation is comparable to the origin of indurations, scirrhus and the like, von Walther distinguishes between urinary incrustations of foreign bodies, in which the phosphoric acid salts of the urine are depo- sited in a similar way to that in which the dippling of a foreign body into a solution of salt produces its crystallization, whereby the outermost layer of most urinary stones consists of phosphates, and urinary concretions, the formation of which takes place as above described. In regard to the several kinds of stones, he considers the relative want of hydrogen in the urinary system, to be in all cases a necessary condition in the production of stone, both as regards the concretions of uric acid, and those which contain oxalate of lime. Excess of azote appears to determine the origin of the former as the want of it does that of the latter. Between the concretions of uric acid and the gout there is a relation similar to that between the phosphatic concretions and the imperfect development of the bony system. 1984. Wetzlar has endeavoured to controvert both these opinions. In opposition to Magendie, he asserts that, although in many cases gravel depends on the absolutely or relatively increased quantity of the uric acid, the production of concretions of uric acid often occurs under URINARY CONCRETIONS. 239 circumstances which do not produce uric acid in excess; nor does any deposit take place when the urine contains very much urate of soda; for instance, in the critical urine of fever, where sediment does not form until after the urine has cooled. Against Walther's theory, Wetzlar objects that stones,.although existing in an organip fluid, are not to be considered as organic bodies; and that their structure and form have nothing which entitles them to be called so: that the assump- tion of a changed condition of the uric acid, and a peculiar affection of the urinary passages, is hypothetical; that an increased production of uric acid is by no means necessary for the formation of stone, as no pre- cipitation of the uric acid is caused by it; that the natural quantity of uric acid is sufficient to yield material for concretion; and that the free state of uric acid, hitherto considered as a natural condition, is an unna- tural one, and the proximate cause of stone. He is of opinion that the uric acid occurs in combination with soda, and when, instead of the weak lactic acid, which is the free acid of the urine (1), and may co- exist with the urate of soda, a stronger acid is secreted, which decom- poses that salt, then the uric acid is precipitated; an opinion which Prout had already advanced, with regard to the occurrence of uric acid with ammonia, in the urine, and the precipitation of the former by the development of another free acid. Although Magendie has not ad- mitted the transmission of acids into the urine, yet Wetzlar believes that an excess of acids in the juices may occur from acid drinks, sour wines, bad sour beer, unnatural acidity in the prime vie, especially in children; and that it may also occur from the relative want of another element, as hydrogen. The secretion of the urine in the kidneys is as- sumed to be from a process of oxidation and combustion; if this be more quick, active, and energetic, then, instead of the weak lactic acid, a stronger acid is secreted, which decomposes the urate of soda. Here the doctrine of Austin and Walther, of a sort of inflammatory irrita- tion of the urinary organs, may, in some cases, be well founded, as an inflammatory condition of the kidneys is the excitant of a more powerful oxidating process for the secretion of urine, and is thus actually the cause of lithogenesis. The connecting medium, the animal gluten, is, according to Wetzlar, not necessary for the production of stone. This always goes on slowly, and it is easy to comprehend how as this preci- pitation slowly takes place, the first molecules of uric acid unite, attract animal matter, especially mucus from the neighbourhood of the fragment, and gradually increase. This, however, is no organic growth. That the materials of which stone is composed are nearly all uncrystallized in it, as von Walther concludes, from its organic formation, is very na- tural, as even without the animal mucus which prevents crystallization, these constituents have little disposition thereto, even out of the body. In sand and gravel there is a deposit, because there is an excessive pro- duction of urate of soda. This salt is very quickly separated and dis- charged with the urine. [(1) Liebig (a) denies altogether the existence of lactic acid, either in the urine, or in fresh milk. He attributes the acidity of healthy urine to the superphosphates of lime, magnesia and soda.—t. t.] (a) Ueber die Constitution des Harnes der Menschen und fleischfressenden Thiere; in Annalen der Chemie und Pharmacie, vol. 1. p. 161. 1814. 240 URINARY STONE, 1985. According to Willis, it is not necessary to seek anxiously after a chemical cause for the deposit of uric acid ; it is sufficient to say, that in certain conditions of the constitution, under the influence of peculiar disturbance of the vitality of the kidneys, a very insoluble constituent is produced from these organs. He considers the production of uric acid, and urates, of oxalates, of cystic and xanthic oxides as very similar, and thinks that, according to the results of modern chemistry, by which a quantity of organic substances may, by a peculiar treatment, be con- verted into one another, the origin of these various concretions may be cleared up. Urea, of which the ultimate elements are 46,65 nitrogen, 19,97 carbon, 6,65 hydrogen, and 26, 65 oxygen, (N4 C4 H4 02,) is con- verted-into uric acid, when the proportions of nitrogen and hydrogen are diminished, and the quantity of carbon and oxygen increased, 33,37 nitrogen, 36,00 carbon, 2,36 hydrogen, 28,27 oxygen (N4 C5 H* O.) If the proportions of nitrogen, caibon, and oxygen, remain as in uric acid, while the quantity of oxygen is diminished about one atom, uric oxide (xanthic oxide, according to Marcet) is produced (N4 O H402.) If the quantities of nitrogen and carbon be diminished, whilst the quan- tities of hydrogen and oxygen are relatively increased, cystin (cystic oxide of Wollaston) is produced, 11,85 nitrogen, 29,88 carbon, 5,12 hydrogen, 53,15 oxygen (N C3 H6 O1.) If, on the one hand, nitro- gen and hydrogen combine, and on the other, carbon and hydrogen, in nearly the same proportions as the former exist in uric acid, and the latter in cystin, oxalic acid is produced, 33,99 carbon, 53,33 oxygen. [(1) Sulpur forms an essential constituent of cystic oxide; and Thaulow (a) ascertained that it contained about 25 per cent, of that element. The accuracy of this statement has been confirmed, by the analyses of two stones in the Museum of the Royal College'of Surgeons (b). According to Thaulow, cystic oxide consists of carbon, 30,01 ; hydrogen, 5,10; nitrogen, 11,00; oxygen, 28,38; sulphur, 25,51; and that it is represented by the formula C6 H6 N. O.^ S2.—t. t.] 1986. Jones assumes on Liebig's principles, that uric acid is produced from tissues which afford albumen and gluten, (gelatine1?) in consequence of a change of matter, and the effect of oxygen. That the uric acid is converted by the influence of oxygen, into alloxan and urea; that, by a further operation of the oxygen upon the alloxan the latter is either changed into oxalic acid and urea, or into oxaluric and parabanic acid, or into carbonic acid and urea; and that the quantity of uric acid which is separated, alternates in inverse proportion to the quantity, which is still further altered within the body, and with the amount of action of the oxygen. On these principles we may, perhaps, establish a general theory of the causes of lithogenesis as follows:—When the health is good, and the operation of the.oxygen perfect, there is no deposit in the urine; if the oxygen act in a slighter degree, there is a deposit of oxalate of lime ; if, in a still less degree, urate of ammonia, or uric acid, is formed. If the health be disturbed, or if the urine become alkaline, from the irritation which the stone produces, the phosphates are precipitated y and if the effect of the oxygen be still further restricted, (a) Annalen der Pharmacie, vol. xxvii. p. 200. 1838. (b) Taylor's Catalogue, above cited, part i. p. 137. CONSTITUENTS OF. 241 only an exceedingly small quantity of phosphoric acid is produced, and carbonate of lime is precipitated. 1987. For the proper explanation of the origin of stone, it seems most convenient first to ascertain the origin of those substances which alone are capable of forming the so-called nucleus of urinary stone, or of being precipitated as gravel, as the deposit of various substances upon a stone once formed is less difficult to understand and to explain. It must not, however, be overlooked that the altered condition of the kidneys, and of the urinary organs in general, has an important influence in the produc- tion of stone. 1988. The general constituents of stones, excepting the animal matter existing in different quantity as the connecting material, are:— 1. Uric Acid. 6. Carbonate of Lime. 2. Urate of Ammonia. 7. Silica (1). 3. Phosphate of Lime. 8. Cystic Oxide. 4. Phosphate of Ammonia and 9. Xanthic Oxide. Magnesia. 10. Iron (1). 5. Oxalate of Lime. Of these substances the following occur in the nuclei of stones, or they may form their entire bulk :— (a) Uric Acid. (d) Cystic Oxide. (h) Urate of Ammonia. (e) Xanthic Oxide. (c) Oxalate of Lime. (f) Phosphate of Ammonia and Magnesia. From these six substances, which form the nucleus, or the entire bulk of a stone, the various kinds of gravel are also produced. Besides the ten above-mentioned constituents, von Walther has also given phos- phate of ammonia and lime, and the acid phosphate of lime (2). Both these substances appear to me doubtful. Not merely is the phosphate of ammonia and lime altogether new as an addition to the contituents of stone, but also new as a combination of phosphoric acid, for phosphate of ammonia and lime, is not admitted by any chemist. In respect to the acid phosphate of lime, von Walther supposes that it alone is capable of forming concretions, but that on the other hand, the neutral phosphate of lime only occurs in the layers. It is to be regretted that von Walther has not given the careful analysis of Fuchs on this subject; as it is difficult to understand how the acid phosphate of lime, which is so very soluble, that even in the air it softens into a molten glass-like mass, can form stones. It is important here also to observe that the acid phosphate of lime is not met with in gravel, in which, how- ever, all the other substances are found which are capable of forming the nucleus of a stone. Walther's assertion that phosphate of lime occurs only in the layers, is contradicted by the observations of Wollaston (a), who examined urinary stones which consisted entirely of phosphate of lime. Their surface, he says, is pale brown, and as smooth as if polished; their interior consists of regular layers, which can easily be separated into concentric plates. These stones are, according to Marcet, very rare. Perhaps this contradiction may be reconciled by the fact that these are such stones as are formed in the prostate gland, (prostatic stones of Marcet,) which consist of a neutral phosphate of lime, coloured by the secretion of the prostate, by which, according to Marcet, these stones can be distinguished from true urinary stones. Or there may perhaps have been a nucleus which'was overlooked. The carbonate of lime (first mentioned by Bergmann, since by Crampton, and most (a) Philosophical Transactions, vol. lxxxvii. p. 395. 1797. 21* 242 URINARY STONE, recently by von Walther) is found, according to the latter, in the outer substance of the stone with the phosphates, but not in the layers, and it appears to enter into no combination with the uric acid, the urate of ammonia, and the oxalate of lime. Goebel (a) describes a stone which consisted, he says, of carbonate of lime 96,025, and animal matter with silica 3,125. Silica is met with but rarely in urinary stones, and is always accompanied by uricacid or oxalate of lime. According to Berzelius, this earth exists in'small quantity in the urine; he derives it from the water and the food. Marcet found in one stone a substance corresponding with the fibrin of the blood (fibrin stone.) Iron is found in combination with uric acid, with phosphate and carbonate of lime, and as iron ochre. Brugnatelli has found benzoate of am- monia in a stone, which he describes among the more rare, consisting of little stones connected together, of a grayish colour, with a smell like castor, light but hard, and containing also phosphate and oxalate of lime. [(1) Silica and iron cannot be said to be general constituents of stones, as they never form an entire stone, and they have only been detected in very minute quanti- ties in some few instances. (2) By acid phosphate of lime is meant, not the super-phosphate, but the neutral or di-phosphate of lime, the "phosphate acidule de chaux " of Fourcroy. Berzelius has commented upon the absurdity of the French chemist describing a solid concre- tion as composed of an acid phosphate of lime. His criticism, however, is only partially correct. The fact is, when the di-phosphate of lime calculus is digested with water, it is decomposed into an insoluble sub-phosphate, and a soluble super- phosphate, which of course possesses an acid reaction. It was from observing this latter fact that led Fourcroy into the error of describing these concretions as com- posed of a super-phosphate of lime. Di-phosphate of lime constitutes the accidental bezoar, an intestinal concretion found in the stomach, &c, of the deer of South America (b). (3) " Calculi, from the human subject, composed entirely of carbonate of lime, are of extremely rare occurrence, and have been noticed only by a few authors. The existence of such concretions was first pointed out by Brugnatelli (c), who describes forty-eight small concretions, which were extracted from the bladder of a young man. They were each about the size of a pea, possessed a lamellar structure, and broke with a shining surface. The same author also mentions several ash- coloured calculi composed of carbonate of lime, with a trace of carbonate of iron, that were taken after death from tbe bladder of a woman. Dr. Prout (d) has also seen small calculi of this salt which were ' perfectly white and very friable.' A remark- able collection of these calculi is in the possession of R. Smith, of Bristol; * * * " five were extracted by the lateral operation from the bladder of a boy aged sixteen, by H. Sully, and the others, fifteen in number, were passed by the urethra of the same patient previous to the operation. The former, are exceedingly irregular in figure, their external surface is rough, and is dusted over with a white powder. The largest of these calculi was about the size and figure of a large almond; when sawn through, it did not appear to consist of concentric layers, but exhibited irregular waved lines of various shades of brown, resembling very closely the section of a compact mulberry calculus. It was so extremely hard as to require a lapidary's wheel to divide it, and the cut surface readily acquired a fine polish. The calculi that were passed by the urethra are about the size of peas, of a rounded figure, with flattened surfaces. They present a compact lamellar structure, and their external surface is of a light brown colour" (e).—t. t.] Uric Acid and Urate of Ammonia. 1989. According to the experiments of Prout and L. Gmelin, it is extremely probable that uric acid does not occur, as Wetzlar asserts, combined with soda ; but in combination with ammonia. Also, that the (a) In Trommsdorff's Neuc Journal de (d) Above cited, p. 93. . Pharmacie, vol. vi. p. 198. (e) Taylor's Catalogue, part. i. pp. 132, (6) Taylor's Catalogue, part ii. p. 252. 133. (c) Litologia Umana—Archiv. Gen. de Med. 1819, vol. iii. p.- 444. CONSTITUENTS OF. 243 acid property of the urine does not depend on free lactic or acetic acid, but on acid phosphate of ammonia, which salt keeps the phosphate of lime in a state of solution {a). That the circumstances stated by Magen- die, to wit, the absolutely or relatively increased quantity of uric acid, and diminished temperature of the urine, is the cause of the precipitation of the uric acid, Wetzlar has indeed too confidently denied ; since uric acid, when, from its being in excess, it is free, and not combined with ammonia, must, on account of its insolubility, be disposed to precipitation. That the sediment of uric acid in critical urine takes place only when it is cooling, may be readily explained by the ammoniacal state of the urine, which exists in such cases. Perhaps the precipitation of the uric acid is rarely the result of its increased quantity, and rather to be met with in gravel than in the actual formation of stone; and the doctrine laid down by Prout is more commonly correct, namely, that the uric acid is often precipitated only because another free acid, as the phosphoric, sulphuric, hydrochloric or carbonic, purpuric or acetic is produced. In consequence of this, the ammonia entirely or in part quits the uric acid with which it was in combination, and is precipitated pure, or combined with a little ammonia; but not, as Wetzlar supposes, by the soda being with- drawn. According to Liebig (b), there is produced, by the action of the uric and hippuric acids upon the phosphate of soda, an acid salt of soda from these acids on the one side, and an acid phosphate of soda on the other side. From which, and from the sulphates contained in the urine, he deduces the acid condition of the fluid. 1990. To attribute the development of such an acid in the urine from an excess of acidity of the juices, cannot be considered groundless, on account of Magendie's assertion that acids, do not pass into the blood. If we cannot, indeed, prove the presence of free acids in the blood, as it has always an alkaline nature, yet, it is to be remembered, that if even no free acid can be found in the blood, yet from its approximation to a neutral state a change is caused, which renders possible the secretion of free acids through the urine. To this former opinion of Magendie's, a later one, advanced in an essay read before the Academie des Sciences, on the 18th of September, 1826 (c), stands opposed, where he brings forward the daily use of sorrel, which contains much oxalic acid, as the exciting cause of almost every stone consisting of pure oxalate of lime. With this, also, Howship's {d) observations agree, which show that if a patient, who, on account of phosphatic gravel, has used acids, take more acid than is necessary to neutralize the alkaline condition of the urine, and to dissolve the precipitated earthy constituents, the white gravel indeed disappears, but red, uric acid gravel is soon produced in its stead. Morichini's (e) experiments also support this view; he found that people who have lived long, and almost exclusively upon sour fruit, present citric and malic acid in their urine. But Woehler's {f) experiments are still more conclusive. (a) Hcidelb. Jahrbiicher. 1823. No. 49. affect the Secretion and Excretion of Urine- lb) Above cited, p. 193. London, 1823. Svo. (c) Revue Medicale, 1826, vol. iv. p. 140. (e) Meckel's Archiv. fur die Physiologie, Froriep's Notizen. 1826. No. 33. vol. iii. p. 467. (d) A Practical Treatise on the Symptoms, (/) Versuche iiber den Uebergang von Ma- Causes, Discrimination and Treatment of terien in den Ham; in Tiedemann's Zeit- some of the most important Complaints that schr. fur Physiologie, u. e. w., vol. i. p. 125. 244 URINARY STONE, Strong mineral acids are not capable of rendering the urine acid, probably because their strong affinity for the soda in the blood destroys its combination with the albu- men, whereby neutral salts are formed, which pass off as such with the urine. Oxalate of Lime. 1991. Walther doubts whether simple oxalate of lime and the con- necting material can form urinary stones. It is frequently'found as the nucleus of a stone, though never alone, but combined with uric acid and urate of ammonia. In the layers it is most commonly found with phos- phates {a). The inquiries of Rapp, however (&), and the stone from six to seven lines long and two thick, noticed by Magendie, and examined by Desprets, which consisted almost entirely of pure oxalate of lime, are in favour of the possibility of such a formation ; as well, also, as that gravel and formless sediment, according to Prout, is never combined with uric acid. 1992. Prout believes that the oxalic acid is produced by the decom- position of the uric acid, as in urinary stones a nucleus.consisting of uric acid is frequently found, surrounded with oxalate of lime; thus the oxalic diathesis follows that of the uric acid, and are allied to each other. He does not, however, suppose that the oxalic acid is in any way produced in the urine by the action of the hydrochloric acid upon the urine ; but he considers it more probable, that the oxalic acid has been already secreted as such from the diseased parts of the kidneys; this oxalic acid then comes in contact with the uric acid which is secreted by the healthy part of the kidneys, and throws down from it the lime, in a state of oxa- late ; perhaps at first in a plastic form, as the somewhat crystallized state of such stones would make us'suppose. Walther contradicts this state- ment (c), as the origin of oxalic acid is more easily deduced from the conversion of the benzoic acid, (which is so similar to it,) free carbonic acid, or lactic acid, contained in the urine, than from the uric acid; for, in oxalic acid, as well as in other vegetable acids, hydrogen and carbon are the oxidizable bases, but the urea is a very azotized production of animal life. Oxalic acid is formed in the urine, not only when the hy- drogen is wanting, in order to saturate all the relative excess of oxygen, and to combine with it as water, but also the nitrogen, as the acid which would be otherwise formed would be uric, which is distinguished from the oxalic acid by the quantity of azote. A relative want of hydrogen seems in all cases to be one of the conditions of the formation of stones, • whether concretions of uric acid or of oxalate of lime. Liebig, Willis, and Jones have held the conversion of uric into oxalic acid, as the con- sequence of a diminished oxygenation. 1993. Besides the production of oxalic acid by the conversion of the uric acid, its origin from the food must also be admitted. In support of this opinion, it must be observed that various vegetables which serve for food, contain a large quantity of oxalic acid ; that Magendie has noticed the production of a stone of oxalate of lime, after long-continued use of sorrel; that in England, where animal food is the most common diet, (a) Above cited, p. 208. schaftlichen Abhandlungen, vol. i. p. 138. (b) Ueber Harnsteine; in Naturwissen- Tubingen, 1826. (c) above cited, p. 219. CONSTITUENTS OF. 245 stones of oxalate of lime are, in comparison with those of uric acid, more rare, whilst, on the other hand, in those countries where chiefly vegeta- bles are eaten, the oxalic stones are much more frequent, as Rapp has noticed in Wiirtemberg, Walther in Bavaria, and I myself in our own neighbourhood. Woehler has, by his experiments, put beyond all doubt the transition of oxalic acid into the urine. 1994. That under the above-mentioned circumstances, which cause the presence of oxalic acid in the urine, the uric acid may also at the same time be diminished, depends on the greater quantity of vegetable food, but is not to be considered a condition for the production of oxalic acid. The ordinary combination of oxalate of lime with uric acid, or urate of ammonia, contradicts this. Wetzlar's (a) assertion, that mul- berry stone is most frequent in childhood, when but little uric acid is contained in the urine, has been disproved by the observations of von Walther, Rapp, and others (6). 1995. If oxalic acid occur in the urine, on account of its greater affi- nity for lime, it takes the latter from the phosphoric acid. In proportion as the phosphate of ammonia existing in the urine is in a more or less acid state, the phosphoric acid may unite partly with this, and partly with the ammonia combined with the uric acid ; and from these different circumstances we may explain how the oxalate of lime can be precipi- tated either alone or in combination with uric acid, or urate of ammonia; how the oxalic diathesis, is preceded or followed by the uric, and how both diathesis stand in near relation to each other. These occurrences may also be explained by deriving the oxalic acid from conversion of the uric acid. Cystin. 1996. Stones of cystic oxide, first discovered by Wollaston, are rare, although Civiale believes that cystic oxide is much more frequently present than has been hitherto supposed. They usually consist entirely of this substance; whence it has been concluded that the cystic oxide diathesis prevents the formation of other stones more than any other dia- thesis (c). Wollaston had seen two stones of cystic oxide covered with a loose layer of phosphate of lime. Bird {d) has, from chemical examination, disproved the assertion that the cystic oxide diathesis is never present with other diathesis ; the simultaneous presence of uric acid diathesis is proved by cases in which stones of cystin have been observed, where the patients, either before or after, have passed stones of uric acid. Yelloly found a stone of cystic oxide, with a nucleus of uric acid, in a child, in whom a new stone was formed a year after, which had also a nucleus of uric acid, though its exterior consisted of phosphates: a stone of uric acid had as its nucleus a small portion of cystic oxide (Henry) ; a stone of oxalate of lime had been previously removed (Prout) ; Civiale found one stone of cystic oxide in the bladder, and one of phosphates under the prepuce; Lassaigne found a small quantity of phosphate and oxalate of lime combined with cystic oxide (e). (a) Above cited, p. 55. (b) Chelius, Ueber Scrotalsteine; in Hei. delb. Med. Annalen, vol. i. pt. 1. (c) Marcet, above cited, p. 77. * , (d) Guy's Hospital Reports, vol. i. p. 492. (e) Civiale, 511. 246 URINARY STONE, 1997. The circumstances under which stones are formed from cystic oxide have, in reference to the place where they are produced, the greatest analogy with those which attend the formation of uric acid and oxalate of lime. They are principally formed in the kidneys, and their origin is to be considered as the consequence of a transformation of the urea, or of the uric acid, to which the cystic oxide is allied by its nitrogenous contents. According to the experiments of Thaulow and others, cystic oxide contains, besides carbon, hydrogen, nitrogen, and oxygen, a large quantity of sulphur (C6 N2 H12 O4 S2.) It is a peculiar circumstance, that persons of the same family are affected with stones of cystic oxide, as out of twenty-two cases of such stones, ten occurred in four families, in which sometimes two, sometimes three individuals were subject to them, and among these, in three instances, brothers (a.) Xanthic Oxide. 1998. The xanthic oxide, uric oxide, first mentioned by Marcet (b), and more precisely defined by the inquiries of Woehler and Liebig (c), occurs very rarely. The earlier opinion that it was nearly allied to, per- haps only a modification of uric acid, has been confirmed by the obser- vations of Woehler and Liebig, who have proved that it has the same constituents as uric acid, but with one atom less of oxygen; that uric acid and xanthic oxide are radically the same, but in two different stages of oxidation (C5 N4 H4 O2.) Xanthic oxide, however, is never found in solution, nor as a precipitate in the urine; yet it is probable that it occurs in the precipitates from uric acid (d). Besides the stone which Marcet mentioned, and that which Liebig and Woehler examined, Laugier (e) has also examined a xanthic oxide stone. Berzelius (/) believes that he has sometimes met with xanthic oxide, or acid in gravel. ' Phosphate of Ammonia and Magnesia. 1999. As the acid property of urine depends on the acid phosphate of ammonia, which salt contains phosphate of lime in solution, it necessarily follows that every change of the urine, in which alkalescence becomes prevalent, whereby the acid which holds those earths in solution is neu- tralized, causes the precipitation of those earths. This applies also to the neutral phosphate of lime, if further observations should prove the possibility of its forming the nucleus of stone; as also to the combination of phosphate of ammonia and magnesia, and of phosphate of lime, which Marcet has described by the name offusible calculus. . Jones (g) divides the phosphate diathesis into true and false; in the former, the urine, in consequence of the general state of the constitution, becomes alkaline, and the phosphates are precipitated; in the latter, the alkalescence depends on retention of the urine, or on a diseased secretion of it, which causes a speedy change of the urea, as in irritation of the mucous membrane of the urethra. (a) Civiale, above cited, p. 608. (e) Journ. de Chimie Med., vol. v. p. 315. (6> Above cited, p. 85-94. 1829. , (c) Poggendorff's Annalen, vol. xli. p. (/) Lehrbuch der Chemie, vol. ix. p. 491. 393. 1837. (g) Above cited, p. 74. (d) Willis, R., p. 108; and on the con- trary Jones, p. 105. CAUSES OF. 247 Connecting Material. 2000. The connecting material, animal mucus, exists in gravel, but specially in all stones, in various quantity, and appears to be subject to different changes in the several kinds of stones. Upon the presence of this material, many ground the distinction between the formation of stone and the secretion of gravel and sand. Others hold that such connecting material is not required for the production of stone, inasmuch as the attraction of the individual constituents suffice for its formation. If we reflect that the inner surface of the urinary organs is naturally overspread with mucus; that in persons troubled with gravel, there is often as great irritation of the urinary passages, as in stone patients, whereby an increased secretion of mucus is caused; further, that in actual blennor- rhceal affections of the mucous membrane of the urinary passages, with copious secretion of viscid mucus, the latter is often mixed with much sand, and yet no stone forms: it follows that the difference between gravel and stone cannot be derived from this connecting material alone. The difference appears for the most part to rest in this;, that in the pro- duction of gravel and sand, the precipitation of the substances forming them follows quickly, and in large quantity from any great excess of living; whilst in the formation of stone, it is slow but more conti- nuous {a.) 2001. Accordingly to what has been hitherto said about the produc- tion of gravel and urinary stone, it may be attributed to two principal causes, to wit, an increased acidity of the urine from the acid naturally existing in it being secreted in greater quantity, or from a new acid being developed; and, an increased alkalescence. The remote causes may be luxurious living, excess, the use of strong wine, want of exercise, mental exertion, especially after eating, the use of food difficult of digestion, as heavy, milky diet, sour beer, sour wine, cider; acidity and irregularity of the bowels, the use of vegetables containing oxalic acid, and circum- stances connected with climate, as low marshy districts. To these may be added the hereditary disposition, specially observed in gravel. In the same manner, the relation between gout and certain kinds of stone, is to be explained ; as also its more frequent occurrence in certain districts, in advanced age, and in the male sex. According to Deschamps {b), the latter peculiarity is only apparent in women, as on account of the short- ness and width of the urethra, little stones readily pass and more rarely need the operation; experience, however, refutes this. Stone is as fre- quent in children as in advanced age, and in them the production of stone is in close relation with scrofulous and ricketty disposition, and with disturbed development of the bony system. Therefore, also, in children, urinary stones contain relatively less uric acid, but on the con- trary, more phosphate of lime, and phosphate of ammonia and magnesia, and the contrary proportions occur in the urinary stones of old gouty persons (c). (a) Henry ; above cited, p. 134. Remarks on the tendency to Calculous Dis. (b) Traite Historique et dogmatique de eases; with Observations on the Nature of l'Operation de la Taille, vol. iv. Urinary Concretions, and an Analysis, &c.; (c) Walther; above cited.—Yelloly, in Phil. Trans., 1829, p. 55.—Eschirsch, 248 URINARY STONE, [The calculi of children consists almost invariably of urate of ammonia. After they have caused irritation in the bladder, they become coated with the mixed phosphates, like all other concretions.—t. t.] 2002. Foreign bodies introduced into the urinary passages, become covered with a crust of phosphatic salts, or often with some uric acid (1). The general opinion is that the phosphatic salts of urine arrange them- selves and form incrustations around the foreign body, according to the same laws by which a foreign body put into a solution of salt, hastens crystallization in it. According to Prout, however, (a), these incrusta- tions arise because the irritation of a foreign body causes an excess of phosphatic salts to be produced; or because the foreign body enters the bladder at a time when the urine there is disposed to incrustation from excess of phosphates. Such foreign bodies as serve for the nuclei of these incrustations pass either through the urethra into the bladder (2), or through wounds (3), or they are swallowed and penetrate through the intestinal canal into the bladder (4). Blood, sloughs, and the like may also be the nuclei of stones. This is indeed doubted by von Walther, but there are stones which have cavities within them, and it is probable that the mucus of the bladder, or a similar albuminous animal substance had, at an early period, filled it, and in the course of several years had dried up. Deny's (6) experience also appears to agree with this view. But Walther's opinion is most decidedly contradicted by Lisfranc's (c) observation ; he found in an urinarystone, as big as the fist, a blackish nucleus of slight consistence, which resembled a clot of blood, and on chemical examination, presented a fibrinous substance (5). One of the just-named animal substances may also be deposited on the nucleus of a stone, over it again a stony mass, so that, if in such stones the enclosed animal substance be dried by time, the nucleus no longer appears to fill up the cavity, and when shaken, it moves and rattles. Two examples in my collection of urinary stones prove this (d). Cruvelhier (e) showed, in the Anatomical Society at Paris, a very large urinary stone, of which the nucleus was originally a clot of blood. [ (1) The circumstances of a foreign body in the bladder becoming coated by uric acid is exceedingly rare. There is only one specimen of the kind in the Museum of the Royal College of Surgeons. It has a splendid piece of steel for its nucleus, A 126.—T. T.] (2) The quickness with which catheters, especially those of elastic gum are coated with earthy deposits after remaining constantly in the bladder for three or four days, is known to every one who has had the least experience. Upon this account, it becomes necessary when a catheter is constantly worn, that if elastic, it should be replaced by a new one, or if of silver or other metal, should be withdrawn, cleaned, end returned every four or six days, otherwise the deposit upon that part of it in the bladder becomes so considerable, that it will often be removed with diffi- culty, and almost always scrape the urethra as it is withdrawn, and add much to the patient's uneasiness. There are few Museums which have not specimens of extra- neous bodies introduced into the bladder, which havebecome nucleiof stones. Inthe College Museum, there are examples of a silver bodkin, of a sewing needle, of a pea, Ueber Lithias; ihre medicinische Begriin- (b) De Calculn, p. 14. dung in zoologischen Bodenverhaltnissen (c) Archives generales de Medecine, 1827. und ihr Zusammenhang mit Ausbildung des vol. i. p. 1. Scelet-Systems; in Med. Correspondenzblatt (d) Eggert, Versuch. die Entstehungdes bayerischer Aerzte. 1843.—Textor Cur- Blasensteines zu erortern ; in Rust's Maga- nin, Versuch iiber das Vorkommen der zin. vol. xiii. pt. iii. p. 367. Harnsteine in Ostfranken. Wilrzburg, 1843. le) Behrend's Allgemeines Repertorium, (a) Above cited, p. 181. p .75. 18^3. Oct. DIVISION OF. 249 a hat-pin, a bougie, a piece of bone, &c. There are also two instances in which soap has formed the nucleus. It is probable that in these cases "a solution of soap had been injected into the bladder; mutual decomposition of the soap and the salts of urine has been the necessary result; the alkali of the former uniting with and forming soluble compounds with the phosphoric and other acids of the urine, while the earthy bases of the urine have precipitated, in combination with the fatty acids of the soap, in the form of a semi-gelatinous sparingly soluble compound, being in fact an earthy soap, consisting of margarate and oleate of lime" (a). In the Museum at St. Thomas's, there is a stone having a large piece of brass nail as its nucleus. And another stone of good size, and about an ounce in weight, which had formed nearly on the middle of a female catheter, that had escaped from the fingers of the surgeon, whilst drawing off the water, who, fearful of getting into trouble, said nothing about the accident. .Some months after, the woman had symptoms of stone, and was cut by Astlev Cooper; the catheter lay across the bladder, and its ends were pretty tightly fixed; but one end having been freed by introducing the finger, it was easily withdrawn. Brodie (b) mentions a hazel nut as forming the nucleus of a stone in a female; and in another case, a man occasionally subject to retention of urine "passed a flower stalk through the urethra into the bladder, using it as a bougie. In an evil hour, the extremity of the flower stalk was broken off, it became incrusted with calculous matter forming the nucleus of a stone," for which he was operated on by Everard Home. He also mentions some small oblong stones from a female bladder, "each of which has a small fine hair running longitudinally through its centre." (3) In St. Thomas's Museum there is a beautiful example of a pin forming the nucleus of an oblong stone. The child, a male infant, had been put upon the floor by his nurse, and immediately began to scream violently, and without any apparent cause. Some months after he had symptoms Of stone in the bladder, for which he was cut by Astley Cooper, and this stone removed. Foreign bodies of such size are sometimes pushed up into the vaginr. and slip beyond the reach of the patient, who, being ashamed of making her condition known at the time when she might be relieved, the foreign body remains fixed, and will produce ulceration of that part of the bladder against which it presses, and incontinence of urine; at the same time also it becomes more or less covered with calcareous deposit. The College Museum has a remarkable instance of this kind, H. a. 13. "A tumbler in an entire state was introduced into the vagina of an unmarried female, about twenty years of age. On her attempting to withdraw it, its upper edge was broken, by which the bladder was wounded, and incontinence of urine produced. In this situation it remained for nearly two years, when it was removed by Mr. Anthony White, who, finding the tumbler to be closely embraced by the vagina, and quite immoveable, broke away the sides of the glass with instruments having notches, filed at their extremities like the wards'of a key, until he was enabled to introduce a lever behind it. * * * A large horizontal slit was found in the bladder immediately above its cervix" (c). My friend Arnott tells me of a woman about forty-two years of age, admitted into the Mid- dlesex Hospital with presumed disease of the uterus, and with incontinence of urine. On examination, a gallipot was found in the vagina, mouth downwards, and coated inside and out with what proved to be triple phosphate. An attempt was made to extract it whole by the application of large-bladed stone-forceps, but the pot was so closely impacted by the swelling of the external parts, that only one blade could be introduced. It was therefore broken with strong «forceps, and removed piecemeal with difficulty. The finger being then introduced into the vagina, a large aperture was found into the bladder, in which was a large stone. As she was much ex- hausted, the removal of the stone was deferred for a few days, and then removed by enlarging the aperture. In the course of a few weeks she was able to retain four ounces of urine in the bladder which she had not been able to do for many years. (4) In the College Museum is an example, H. a. 14, of a pin, which had been swallowed five years, forming the nucleus of stone in a young man of twenty-two years of age, which had caused symptoms only the latter two years. It was re- moved by the lithotritic operation. (5) Astley Cooper mentions a case in which, having removed a triple phos- (a) Taylor's Catalogue, part, i. p. 129. (b) Lectures, above cited, p. 245. (c) Taylor's Catalogue, part, i. p. 129. Vol. hi.—22 250 URINARY STONE, phate stone, "the disease.returned, and he again performed the operation, and found a large coagulum of blood in the bladder surrounded by a triple phosphate deposit" (a). In the College Museum there is a stone H. a. 7, " consisting of uric acid, deposited upon a hollow crust or shell of impure oxalate of lime. This crust was most probably formed upon a clot of blood, which has afterwards shrunk" (6).] 2003. Urinary stones are divided according to their situation, the mode in which they arise in the urinary passages, according to their external differences, and according to their chemical composition. 2004. According to the situation where they are found stones are dis- tinguished as— a. Renal Stones Calculi renales Nierensteine. b. Ureteric ,, ,, ■ ureterici Steine in den Harnleitern. c. Vesical , , , , vesicates Blasensteine. d. Urethral , , . , , urethrales Steine in der Harnrbhre. e. Stones which form in collections of urine in the cellular tissue. Stones either lie loose, or they are firmly enclosed by the walls of the cavity, or are connected with them. 2005. The external characters of stones are very different, and a divi- sion founded upon such difference is only so far of value, as it gives sometimes a clue to their internal chemical composition. Their structure is more or less solid, granular, sandy, chalk-like, crystallized, friable, brittle ; their surface is smooth, tubercular, mulberty-like ; their interior compact, homogeneous, laminated, consisting of various layers. The layers usually show mixed and varied colours, as gray, white, reddish- yellow, brown, black, violet, and so on. The middle ox nucleus (Kern, Germ.; Noyau, Fr.,) of the stone is formed either of a foreign body or consists of one of the substances already mentioned (par. 1988.) Stones composed of uric acid have a brownish or yellowish colour, a smooth, but sometimes tubercular surface, a radiated fibrous fracture, and mostly an oval or flattened form ; when cut through, they are generally found made up of concentric layers. Stones formed of urate of ammonia have nearly the same figure as those of uric acid, but have a milk and coffee colour; they are composed of concentric layers; their fracture is very close and similar to that of a hard chalk stone. Mulberry stones, however complicated they may be, contain in their nucleus or in their layers oxalate of lime (1). Their colour is dark brown, approaching to black; they are hard, when cut through present an im- perfectly lamellated structure ; they rarely exceed a moderate size. If in these stones there be not this irregular surface, the cause seems to be the simultaneous existence of several stones, and their consequent fric- tion, (c). Marcet's hempseed stones are smooth, contain oxalate of lime (2), and are pale coloured. Stones consisting of the earthy phosphates have a white or grayish-white colour, are friable, and brittle, and only in rare cases hard and compact, (a) Surgical Lectures, vol. ii. p. 242. alate du Chaux, qui ne sont pas murales; in (6) Taylor's Catalogue, part. i. p. 85. Annales de Chimie et de Plysique, vol. vi. p. (c) Martkes, Sur des Concretions d'Ox- 220. DIVISION OF. 251 and when broken they present a crystalline and more or less transparent structure. The stone consisting of phosphate of lime has mostly a pale-brown colour, is smooth as if polished ; its structure consists of regular plates, which are striped perpendicularly to their surface ; it is rare, and seldom attains moderate size (a). The stone, consisting of a mixture of phosphate of lime and phosphate of ammonia and magnesia (fusible stone) is usually white and very friable. It resembles a lump of chalk, and leaves a whitish stain on the fingers ; it is in general not laminated, but sometimes separates into layers, the interspaces of which are often filled with glittering crystals. Those which have no layers often attain considerable size. The cystic oxide stones are usually crystallized throughout, yellowish, semi-transparent, iridescent ; if examined with a lens, an irregular group- ing of granules is observed, which, in large stones, are separated by interspaces; this, according to Civiale, seems to prove that the cystin is not deposited on its nucleus in a fluid form, and this appears from the structure of the stone, which, at least in its pure state, is wrinkled like shagreen. These stones are usually small, and do not exceed the middle size. Civiale has, however seen three stones of this sort of con- siderable size (3). When cystic oxide is combined with other sub- stances, for instance, with earthy substances, the stones appear to be so modified by the nature of their combination and the proportions of their constituents, that there is great uncertainty about the nature of the stone. Stones of xanthic oxide have a pale-brown, smooth, glossy, in part whitish, soft and earthy surface ; when broken they have a brown flesh- colour. They are made up of concentric and easily separable layers, and have not any crystalline or fibrous structure. By rubbing they become smooth, with a wax-like gloss, and have nearly the same hard- ness as stones of uric acid. Those stones which contain carbonate of lime are of a chalky colour, hard, and friable. Smith (b) has described stones of this kind, which closely resemble mulberry stones. Urinary stones sometimes smell of urine ; in sawing them through some have a peculiar animal odour, resembling sawn bone or musk ; many have no smell at all; a few have a distinct and well-marked flavour. Their sizOis very various ; it appears, however, in some de- gree relative to their composition. Their shape depends on the place in which they are found, and partly on their number (4). [(1) Several mulberry stones have a nucleus of uric acid. (2) Hempseed calculi consist either of oxalate or of urate of lime, either pure or mixed with urate of ammonia. (3) A cystic oxide stone found in the Museum of St. Bartholomew's Hospital half of which is now in the College Museum, weighed, when entire, 740 grains. Another specimen, in the Museum of University College, (London,) weighed 850 grains. (4) Only three xanthic oxide stones have ever been seen .—Marcet's, which weighed only eight grains; Langenbeck's, about the size of a small hen's egg, first examined by Stromeyer, and afterwards by Liebig and Wohler; and that de- scribed by Laugier.—t. t.] (a) See par. 1988 [note]. (b) Medico-Chirurg. Trans,, vol. xi. p. 14. 252 URINARY STONE. 2006. The division of stones according to their chemical composition has been arranged in various ways by Fourcroy, Brande, Thomson, Wollaston, Marcet, Yelloly, and Taylor, and the grounds upon which this division has been founded are either the simple or compound nature of the stone, or the prevalence of one or other substance. It seems most convenient to divide urinary stones according to the principles laid down by von Walther, who gives the acids entering into their compo- sition as their distinguishing characteristics. 2007. According to these principles may be distinguished :— Firsj;, Urinary incrustations of foreign bodies. These consist of phos- phates, often also with some uric acid. .Second, Urinary concretions without foreign bodies. a. Stones of pure uric acid or urate of ammonia. These are soluble in the fixed alkalies, with or without giving off ammonia. b. Stones which contain oxalate of lime. This is found in the nucleus, either pure or commonly combined with urate of ammonia, most com- monly in the interspaces between the nucleus and the crust, which latter usually consists of phosphates. Sometimes they contain a little silica in a state which is still questionable. They are insoluble in alkalies, and soluble with difficulty in dilute acids. c. Stones consisting of cystic oxide, sometimes covered with a crust of phosphate of lime. A piece of cystic oxide placed upon ignited char- coal gives out a garlicky or phosphoric smell ; on a platina plate, heated to redness, its sulphur blackens the plate to the extent of some lines. d. Stones of xanthic oxide, soluble in hydrochloric acid, although with more difficulty than uric acid, without the least development of gas, form, after evaporation, a lemon-coloured residuum, which dissolves in water with a pale yellow colour. e. Stones consisting of phosphoric acid in combination, so as to produce neutral salts, either of phosphate of lime or phosphate of ammonia and magnesia, simply or combined, with phosphate of lime; or they have a nucleus of uric acid or urate of ammonia and the crust consists of phos- phates, or of these and alternating layers of uric acid. f. Stones containing carbonate of lime. These have a nucleus of urate of ammonia, and the carbonate of Itme is mixed with phosphates. They effervesce with acids. 2008. The frequency of the different kinds of stoics varies according to the circumstances of climate, mode of life, and soon. The uric acid stones, however, occur most frequently, so that, according to Prout, they make one-third of the whole number. To this may be added, that uric acid, in most other instances, forms the nucleus around which other layers are deposited, so that its frequency may perhaps be estimated at two-thirds. Oxalate of lime stands next to uric acid, and then follow the phosphates. If the number of substances composing stones be reviewed, they may be divided into simple and compound, thus : Simple. 1. uric acid; 2. urate of ammonia; 3. oxalate of lime ; 4. phosphate of lime, 5. phosphate of ammonia and magnesia. Double. 1. uric acid and phosphates; 2. uric acid and oxalate of lime; 3. urate of ammonia and phosphate of ammonia and magnesia; 4. phosphate of lime and phosphate of ammonia and magnesia. AMORPHOUS URINARY SEDIMENTS. 253 Triple. 1. uric acid and both phosphates; 2. urate of ammonia and both phos- phates ; 3, oxalate of lime, with uric acid or urate of ammonia and phosphates; 4. carbonate of lime, with phosphate of lime and iron. Quadruple. 1. uric acid, with oxalate of lime and phosphates; 2. uric acid, with urate of ammonia, silica, and a phosphate. Quintuple. Uric acid, with urate of ammonia, oxalate of lime, and phosphates. [Amorphous Urinary Sediments. The deposits from the urine, either as mere sediments without form, or in a state of crystallization, as gravel, are of so great importance, both as regards themselves, and in reference to the production of stone, that I have taken the liberty of supply- ing the deficiency of the special consideration of the subject of urinary sediments in Chelius's work, by the following extracts from the excellent work of Dr. Prout. " Lithic or Uric Acid Sediments. These sediments assume at different times very different appearances, especially in point of colour; and they occur at different times, and in different persons, of almost every shade of colour, from nearly perfectly white to deep mahogany brownish red. * * * I shall consider them under three heads only, which will be found quite sufficient for all practical purposes, namely: first, yellow sediment; second, red or lateritious sediments; and third, pink sedi- ments. " 1. Yellow Sediments. These sediments vary in colour, from nearly white to the wood-brown of Werner, a colour which is stated to be identical with that of ripe hazel nuts. They consist essentially of the lithate (urate) of ammonia, tinged with the colouring principle of the urine, but usually contain more or less of the phosphates, and sometimes a little of the lithate (urate) of soda. In general, perhaps, the nearer they approach to white, the more of the phosphates they contain; but there are many exceptions to this, and I have seen sediments belonging to this class almost perfectly white, and consisting of nearly pure lithate (urate) of ammonia. This class of sediments may be termed the sediments of health, if the term may be allowed, being such as are produced in the urine of healthy or slightly dyspeptic individuals, by errors of diet and all the other circumstances before mentioned which seem, independently of actual fever, to procure turbid urine. Perhaps there is no healthy individual whose urine does not occasionally deposit this species of sediment. * * * When these sediments are of an unusually pale colour, as is sometimes the case, a tendency to the phosphates is indicated. Children are very subject to this form of sediment; and in them, as well as in all who labour under such a suscepti- bility, it is frequently the forerunner of gravel or calculus. Indeed nothing is more common than for this form of sediment to alternate in the urine of the same person with the crystallized sediment ox gravel, to be presently described. " 2. Red or Lateritious Sediments. These sediments vary in tint from nearly white, in which state they are with difficulty distinguisheoVfrom the last variety, to a deep brick-red or brown. They consist essentially of the lithate (urate) of ammonia, or lithate (urate) of soda, tinged with a large proportion of the colouring principle of the urine, and more or less of the purpurates of ammonia and soda. Sometimes, also they contain a small proportion of the earthy phosphates.t In general, the deeper the tint, and the more approaching to brick red, the more of the lithate (urate) and purpurate of soda they contain ; but there are some exceptions to this observation. When the purpurates exist in the urine, (indicating, as was formerly attempted to be shown, the secretion by the kidney of nitric acid,) feverish, or inflammatory ac- tion, is almost constantly indicated; and this law is so general, that I have never seen a decided exception. * * * They owe their peculiarity of tint to the colouring matter of the urine, which, in common with all its other principles, appears on such occasions to be secreted more copiously than usual. Hence urine which deposits these sediments is usually of a deep red or brown colour, and of high specific gravity. The deeper the colour of the sediment, and the more approaching to red, the more severe in general the symptoms. * * * The urine of all persons labour- ing under feverish and inflammatory affections and whose urine is naturally healthy, is liable to deposit this species of sediment. * * * There are certain 254 AMORPHOUS URINARY SEDIMENTS. diseases, also, in which this variety of sediment appears to occur in a greater de- gree, and in a more decided form than usual; such are gout, also rheumatism, he- patic affections, &c. " 3. Pink Sediments. The third and most rare variety of amorphous sediments is what is usually denominated pink sediments, the colour of which is very aptly ex- pressed by the term pink. Like the other varieties, they consist essentially of the lithate (urate) of ammonia ; but they differ from both these, in being almost entire- ly devoid of the yellow tint derived from the colouring matter of the urine; and con- sequently, in owing their colour chiefly to the purpurate of ammonia. This class of sediments, therefore appears to indicate the absence of the large proportion of the colouring principle of the urine, so constantly present in active inflammatory fever, and to denote the secretion of a greater quantity of nitric acid, and the consequent formation of more of the purpurate of ammonia. * * * The most perfeet specimens of this kind of sediment which I have ever seen, were obtained from the urine of dropsical individuals : they occur also occasionally in the urine of the hectic, and of those obviously labouring under eertain chronic visceral affections, especially of the liver." (p. 121-25.) "Besides these amorphous sediments, consisting chiefly of lithic (uric) acid, I have seen two or three instances in which large quantities of perfectly white lithate (urate) of soda were deposited from the urine. In one ease, in particular, the quantity was immense, and voided not only mixed with the urine, but in a state of consistency like mortar, especially during the night, so as to produce considerable difficulty in passing the urine. The urine was acid." (pp. 127, 28.) Phosphatic sediments. " The phosphates, like the lithates, (urates,)" says Prout, "appear in the urine under two distinct forms, viz., in an amorphous state, and in the crystallized form; but here the analogy ceases, for in the ease of the lithates, (urates,) the amorphous form is of comparatively the least consequence, whereas when the phosphates are concerned, the amorphous sediment is by far the most im- portant, and the crystallized form is usually of a much milder character." On this account Prout considers "the crystallized form, in the first place, as a preliminary step to the more formidable disease." (p. 174.) It will be more convenient, how- ever, for our present purpose, to reverse his arrangement, and first to notice the amorphous phosphatic sediments. " These sediments consist invariably," says Prout, " of a mixture of the phosphate of lime, and of the triple phosphate of magnesia and ammonia.—[Note.—I am aware that it is the opinion of many eminent characters, that the inner coat of the bladder is the source of the earthy matters deposited by the urine on these occasions. I do not deny this altogether; but, on the contrary, think that the posphate of lime, at least, is sometimes derived from this source—the inner coat of the bladder apparently assuming, in such instances, the character of the inner surface of the abscess sometimes found in the prostate gland, which is known to secrete this earthy salt in great abundance. I am doubtful, however, if any portion of the triple phosphate is ever derived from this source, but from the kidney only, from which same souree, in various cases, a large proportion of the phosphate of lime is likewise undoubtedly derived.]—The proportions of the two salts vary very much in different instances ; but, sometimes, the phosphate of lime seems to constitute by far the greater proportion, and, in this case, the symptoms are commonly much more decided and severe; and it is to this form of the disease that the following observa- tions are to be understood as chiefly applicable. A deposition of the earthy phosphates from the urine has been long observed to be attended by very distressing symptoms, though no one seems to have hitherto generalized them. They consist in great irritability of the system, and derangement of the chylopoietic viscera in general; such as flatulency and nausea, obstinate costiveness, or peculiarly debilitating diar- rhoea, or both frequently alternating; and the stools are extremely unnatural, being either nearly black, or clay-eoloured, or sometimes like yeast. These are always accompanied by more or less of a sensation of pain, uneasiness, or weakness, in the back and loins. There is a sallow, haggard expression of countenance; and as the disease proceeds, symptoms somewhat analogous to those of diabetes begin to ap- pear, such as great languor and depression of spirits, coldness of the legs, complete anaphrodisia, and other symptoms of extreme debility: and the disease, if not speedily checked, seems capable of ending fatally. The urine in this form of dis- ease is invariably pale-coloured, and, upon the whole, voided in greater quantity than natural. Sometimes (generally, I think, by day) it is voided in very profuse GRAVEL. 255 abundance, and, in this case, is of very low specific gravity; 1 *001 or 1 '002, for example. At other times, it is voided in less quantity, and its specific gravity is proportionally higher; but it is seldom very high, that is, surpassing 1 '025. In the former case it is generally perfectly pellucid, and colourless, and deposits no sediment; in the latter, it is sometimes opaque when passed, and always, after standing for a greater or less time, deposits a most copious precipitate of the mixed phosphates, in the state of an impalpable powder. In all cases the urine is extremely prone to decomposition, becomes alkaline by the evolution of ammonia, and emits a most disgusting smell. With respect to the causes of this complaint, they may be either general or local; for the most part, however, they seem to partake of both characters. A large pro- portion of those cases which have come under my own observation, has been dis- tinctly traced to some injury of the back. This injury has been of a character not very capable of being understood or described ; but perhaps some idea of it may be acquired by my stating, that for the most part it has arisen from a fall from a horse, in which the person has received a violent general concussion of the spine, and often at the same time some local injury about the back, but not of such a nature as to confine him long, or to lead him to think that he has received any material injury; and generally it has been quite forgotten till the patient's attention has been called to the subject. Among the general exciting causes may be also mentioned severe and protracted debilitating passions, excessive fatigue, &c. The local causes are generally some irritation about the bladder, or urethra, especially when operating constantly for a considerable length of time ; as, for example, any foreign substance introduced into the bladder, and producing irritation of that organ, including all sorts of calculi under certain circumstances; the retaining of a bougie or catheter in the urethra; strictures of the urethra in some rare cases, and in particular constitutions; all which, and many other similar causes, are capable of producing, in a greater or less degree, a condition of the urine more or less resembling that above described, and readily depositing the phosphates. Thus it has been long known that any foreign substance introduced into the bladder almost invariably becomes incrusted with the phosphates, and not the lithic (uric) acid. With respect to the proximate cause of this form of disease, we may suppose it to consist in a diminished or sus- pended action of the usual acidifying powers of the kidneys, and the formation, instead of lithic (uric) acid, of a greater quantity of alkaline matter than natural, as urea, (equivalent to ammonia,) and particularly of magnesia and lime; but this being little more than a simple expression of obvious facts, of course throws no light upon the immediate cause of these depraved actions." (p. 177-82.) " Oxalate of lime very rarely, if ever, appears alone under the form of an amor- phous sediment. In some instances, it occurs with the lithic (uric) amorphous sediments; but even this is not very common." (p. 153.) Cystic oxide. Prout had the opportunity of examining the urine of a man of thirty years old, who had passed a stone of pure cystic oxide. He found it had "a yel- lowish green colour, and strong peculiar smell. It very faintly reddened litmus paper, and its specific gravity was 1,022. There was a slight deposition on standing for some time, consisting of a mixture of the cystic oxide with a little of the triple phosphate. A considerable proportion of the cystic oxide was precipitated from the urine on the addition of acetic acid, which of course held at the same time the phos- phates in solution." (p. 167.) The treatment of these several kinds of sediment will be considered in speaking of the treatment of the various kinds of gravel.] I.—OF GRAVEL. (Sabulum, Arena, Lat.; Gries, Germ.; Gravelle, ou Gravier, Fr.) 2009. The term gravel is applied to-sand, or small crystallized stones, of different colour, form, and number, which are voided with the urine. It consists usually of uric acid, or urate of ammonia, when it is reddish; or of oxalate of lime, when it has a dark blackish green; or of phosphate 256 GRAVEL—SYMPTOMS. of ammonia and magnesia, where it is whitish ; or of cystic oxide, when it has a bright yellow colour. Crystalline deposits, of different kinds, are never met with, at the same time, in the same urine, although, not unfrequently, accompanied with formless and dust-like sediment (a). Magendie (b) notices a peculiar kind of gravel, in which the sediment of the urine consists sometimes of a small quantity of white powder, with a great number of small hairs, the length of which varies from two lines to an inch and more ; some- times it is whitish, irregular, and of so little consistence, that it may be crushed be- tween the fingers, without the fragments, which are connected by the little hairs, being separated; but they remain hanging together in a sort of cluster. These hairs can be separated only by maceration. Magendie calls this hairy gravel (gravelle . pileuse,•) it consists of phosphate of lime, and some magnesia, and uric acid. Gueranger (c), speaks of a gravel composed of silica. In reference to xanthic oxide gravel, see par. 1998. 2010. The symptoms of gravel are very various; sometimes it causes little or no inconvenience; often only in making water: frequently it is accompanied with pain or weight in the loins ; the kidneys, ureters, blad- der, and urethra may be, however, severely irritated; and suppression of urine, inflammation, and fever, may result from it. In most cases it is accompanied with disturbance of the digestive organs, acidity of the stomach, flatulence, and the like. Patients labouring under this disease frequently complain of heat and dryness in the throat and gullet, and are therefore constantly hawking and spitting. The complaint is often accompanied with organic disease of the kidneys, or of the urinary passages. The general health and appearance will often remain good for a long while with deposits of uric acid (1): but phosphatic gravel is always accompanied with symptoms of increased sensibility and irrita- bility, general weakness, disturbed digestion, and unhealthy pale coun- tenance. In phosphatic gravel, the urine is most generally pale, after standing some time a glistening film is formed on its surface, which con- sists chiefly of phosphates ; little crystals often attach themselves to the vessel. The specific gravity of the urine is often very much altered; and it very readily becomes putrid (2). [(1) "This form of sediment (crystallized uric acid) varies considerably," says Prout, " in its colour and appearance, according to circumstances. When unaccom- panied by fever, its colour is alwdys identical with the deeper tints of that of the first (yellow) class of amorphous sediments before described. When it is accompanied by fever, it is generally more or less of. a red or lateritious colour. I have never seen this form of sediment of a pink colour, and, for obvious reasons, it is not likely that such an occurrence should take place. Sometimes large quantities of impure or imperfectly crystallized lithic (uric) acid is voided by old people in the shape of globules, varying in size from a pin's head to that of small peas : these are generally pale-coloured. Occasionally, also, when the kidney is diseased, large irregular masses of this acid, in an impure state, are voided. * * * Children, in general, and particularly the children of dyspeptic and gouty individuals, or who inherit a ten- dency to urinary diseases, are exceedingly liable to lithic acid deposits in the urine * * * If the child be attended to, there will be found to be a frequent desire to pass urine, which is voided in very small quantities, and with manifest uneasiness. The irritation about the urinary organs also frequently induces the child to wet the bed by night, &c. * * * Between the age of puberty and forty, there is, generally speaking, less disposition to the formation of lithic (uric) acid deposits than at any other period of life. * * * About the age of forty, an important change com- monly takes place in the constitution, which for the most part materially influences (a) Prout, above cited, p. 85. (6) Revue Medicale, 1826. vol. iv. p. 140. (c) Journal de Chimie Medicale, vol. vi. p. 129. 1830. CONSTITUENTS OF GRAVEL. , 257 the disposition of lithic acid in the urine. It willbe generally now observed that the lithic acid is apt to be deposited at intervals in larger quantities than usual, and that for some time previously to this occurrence, there is more or less of feverish indisposition and derangement of the general health : about this period of life, also, there is a disposition in the constitution, at the above periods particularly, to separate the lithic (uric) acid in a concrete state, thus giving origin to the formation of renal calculus. * * * Frequently about the age of sixty or seventy, another change takes place in the mode in which the lithic acid is separated from the system. At this period of life the urinary organs not only begin to participate in the general decay of the constitution, but are apt to be deranged in a particular manner from other causes, and more particularly to suffer from the delinquencies of early life. Frequently, also, they become organically diseased, and this circumstance, in conjunction per- haps with others that will be noticed hereafter, produces a disposition in the system to secrete neutral urine, or even the earthy phosphates. Under these circumstances, where the urine had previously for years deposited the lithic (uric) acid chiefly in the state of crystals, these will in a great measure disappear, and instead of them, impure or imperfect lithic acid, in the shape of minute globules of various sizes, will be separated from the kidneys in great abundance. In most of these cases, there is a good deal of pain in the back, and irritation about the urinary organs, even when the concretions are only of small size. In others, there is much less irritation under these circumstances than one could imagine. In all instances, however, this may be considered as a most dangerous state of disease, not only from the constant liability of the patient to the formation of renal or vesical calculi, which all other cir- cumstances likewise conspire to render probable. But, on the other hand, from the danger there is of suddenly checking the secretion of lithic (uric) acid, which is sometimes followed by great derangement of the general health, and apoplexy." (p. 130-35.) (2) " Crystallized sediments, composed of the phosphates, almost invariably con- sist," says Prout, "of the triple phosphate of magnesia and ammonia, and exist in the form of perfectly white shining crystals.— [Note.—I have said almost invariably ,■ for, if I am not mistaken, I have once or twice seen a crystallized compound of the triple phosphate of magnesia and ammonia, and the phosphate of lime. These crystals were much larger 1han those of the triple phosphate, and less distinctly formed.]—This form of disease sometimes occurs alone, but very frequently it alternates, or is accompanied by the pale-coloured lithic (uric) amorphous sediments, or the amorphous variety of phosphatic sediment." When the triple phosphate of magnesia and ammonia "abounds very much, the crystallized deposit is formed before the urine is discharged from the bladder, and consequently immediately sub- sides to the bottom of the vessel in which it is passed ; in this case, the urine is alkaline when voided: most generally, however, the crystals do not begin to form till the urine has become cool and sometimes not till it has begun to putrify: and these circumstances indicating the periods when the urine becomes alkaline, may be considered as pointing out the degree of severity of the disease. * * * It may be also remarked that children are more subject to this form of deposit than adults; a circumstance perhaps to be referred to the irritability of the system at this age, and the great derangement of the digestive organs to which they are subject." (p. 174-77.) Oxalate of Lime. "Its appearance is still more rare," says Prout, "under the form of crystallized gravel," than under that of an amorphous sediment. "I have only seen one instance of this, and am able to refer to one more. Brande states, also, that in this diathesis there is little or no sand or gravel voided." (p. 153.) Although oxalate of lime can scarcely be said to form gravel, yet it is very fre- quently deposited from the urine in the form of small flattened octohedral-shaped crystals. Indeed, as far as my own observation goes, there are very few cases of habitual disorder of the digestive functions, in which this salt cannot.be detected in the urine, either alone, or as is most commonly the case, accompanied by uric acid and urate of ammonia. Persons in whom this, diathesis prevails are usually of a spare habit, with a pale countenance, and have more or less nervousness of manner about them. They usually complain of a feeling of languor, and disinclination to mental or bodily exertion, pain in the loins, and uneasiness and weight, if not of pain, in the region of the stomach, particularly after eating; palpitation of the heart, and a capricious, sometimes an inordinate, appetite, although a small quantity of 258 URIC ACID GRAVEL, food produces oppression with nausea. In general they suffer from acidity of the stomach, and are subject to itching and tingling of the skin, boils, and cutaneous eruptions, particularly of the scaly kind. Their urine is generally acid when first passed, and perfectly bright; on cooling, it becomes more or less turbid, from the deposit of urate of ammonia, with crystals of uric acid and oxalate of lime. Some- times no deposit of urate of ammonia occurs, the urine remains perfectly clear; but crystals of oxalate of lime are to be found entangled in the mucus of the bladder, which has subsided to the bottom of the vessel. In order to detect this salt in the urine, it is merely necessary to allow the urine to stand for some hours, to pour off the greater portion of the fluid, and to place a few drops of the remaining liquid on a glass plate beneath the microscope, using a power of about 200 linear. The oxalate of lime will then, if present, be observed in the form of very regularly shaped highly flattened octohedra. If the drop of urine be allowed to evaporate to dryness, the crystals will appear as squares, with a dark square in the centre, the sides of which face the angles of the outer squares, somewhat resembling this diagram. When-much urate of ammonia is present, it is well to add some boiling water to the deposit, which dissolves the whole of that salt, and allows the oxalate to be distinctly observed. The causes producing this diathesis, independent of the use*of food containing oxalic acid, as rhubarb tarts and sorrel, are those habits which are calculated to diminish the vital energy, and the powers of assimilation, and of these severe mental study, or anxiety, or inordinate venery, appear to me to be the most common. The treatment must be guided by general principles; an entire change of habits, change of air, and a vigorous diet, consisting almost exclusively of meat and bread, with the avoidance of sugar in every form, are the most important circumstances to be attended to. The nitro-muriatic acid, which has been much recommended, causes certainly in many cases, the oxalate of lime to disappear from the urine, and frequently substi- tutes that of uric acid. Its use cannot, however, be long persisted in, and without attention to the above rules, it has no permanent advantage.—t. t.] 2011. As to the aetiology of gravel and its various kinds, all that has been already said generally applies, and therefore its indica' ions determine the treatment. Its object must be to prevent the increased production of the acid, or the formation of a new one, and to encourage the removal of the gravel already formed. If the gravel cause violent pain, difficulty in making water, fever, and the like, these must be got rid of by blood-let- ting, leeches, cupping on the loins, lukewarm baths, fomentations by calomel with antimony and opium, or hyoscyamus, by the introduction of the catheter, and so forth, according to the different state of the patient, and the violence of the symptoms. If there be suspicion of any accom- panying local disease in the kidneys after the inflammatory symptoms have been soothed, a large galbanutn plaster, an issue, or a seton in the loins may be useful. 2012. In uric acid gravel, the excessive production of the uric acid must be prevented, and the excessive acidification of the urine by other acids must be guarded against. The patient must keep to a strict diet, both as regards the quantity and quality of his food; all substances con- taining much azote, especially salted and dried meats, acid fruits, thin soups, wine, especially that which is acid, and bad beer must be most carefully avoided. The proper action of the skin must be attended to by wearing flannel next the body, and regular relief from the bowels by proper exercise, and avoidance of mental excitement. It must be sought to neutralize the acid by the use of alkalies, carbonate of soda, of potash, of magnesia. These partly neutralize the acids in the alimentary canal, and in the juices, by which the ever-continuing decomposition of the urate of ammonia is got rid of, and partly by the passing over of the TREATMENT OF. 259 alkalies into the urine, the solution of the gravel is effected. The car- bonate of soda and potash must be given dissolved in water, and the dose gradually increased. Frequently during their continued use, the digestion is disturbed, which renders their suspension necessary. Car- bonate of magnesia is given either in powder or mucilaginous fluids; it is less effective, but more easily borne. According to Prout (a), if these remedies are to be really efficacious, they must not be given alone, but combined with alteratives and purgatives. A pill of calomel and anti- mony should be given at night, and a solution of Rochelle salts and car- bonate of soda in bitter drink next morning. Through the day this mixture should be taken twice or thrice, or a little magnesia in a glass of soda water. This treatment must be continued for a certain time, according to the severity and obstinacy of the symptoms, and the altera- tive pills given at more distant intervals, with a corresponding diminution of the doses of the other medicines. If violent irritation also exist, opium, or hyoscyamus, which is still better, must be employed. Hydro- cyanic acid may be given with advantage in flatulence and acidity of the stomach; and, if there be gouty complication, the vinum seminum col- chici. This treatment must, however, be modified according to the cir- cumstances of the case. The easier discharge of the gravel is promoted by drinking much water, or any diuretic mineral water, as that of Vichy, Wildungen, Sellers, Carlsbad, and the like. Wetzlar (6) proposes for uric acid gravel a solution of borax, as it dissolves the uric acid with great readiness, and perhaps acts less injuriously on the digestive organs than alkalies. The peculiar property of vegetable acids, combined with alkalies, being converted in animal bodies into carbonic acid, and as such to pass into the urine, led to the proposal of employing them instead of carbonic acid, as they are more easily borne than it, and allow of greater variety. Most vegetable alkalies can be used for a length of time, and in large quantity, without disturbing the digestion, and are not unpleasant to take, as the supertartrate, tartrate, and borate of potash, Seignette salts, acetate and citrate of potash and soda; cherries, strawberries, and different kinds of fruits (c). According to Jones, the question of the treatment of the uric acid diathesis depends upon which way the greatest oxygenation can be produced upon the uric acid in the body. This appears to be attainable, first, by the large addition of oxygen, as by exercise, cold air; by medicine, as carbonic-acidized waters and iron; second, by the diminution of the other substances on which the oxygen acts more easily than on the uric acid, that is those bodies which consist of hydrogen, carbon, and oxygen, by their exclusion from the food, and their removal by purging and sweating remedies ; third, by retaining in solution all the uric acid formed, by means of water and alkalies. Upon the effect of vegetable diet on the diminution of uric acid, compare Liebig npon the composition of the urine (d). Wilson Philip (e), on the contrary, has come to the conclusion, after a number of experiments, that a diet for the most part animal diminishes the deposit of uric acid, and increases that of the phosphates. [" Different doses of the alkaline remedies will be required," says Brodie, " in different instances. Indeed a good dealof care is generally necessary to adjust the dose to the peculiar circumstances of the individual case. If you give too little of the alkali, the result is not obtained, and the lithic acid is deposited, although in smaller quantity. If you give too much, you not only prevent the formation of the red sand, but you render the urine alkaline and a white sand (the triple-phosphate of ammonia and magnesia) is deposited in its place. Other ill consequences follow fa) Above cited, p. 78. (c) Woehler, p. 315. {b) Above cited, p. 78. (d) Above cited, p. 193. (e) Medical Transactions, vol. vi. p. 212. 260 URIC ACID GRAVEL, the too liberal exhibition of alkalies. They alter the quality of the blood. After some time the patient is liable to petechiae; he perspires too easily; becomes low- spirited, and less capable than when in health of physical exertion. Magnesia does not produce these effects at any rate, not to ihe same extent, as no more of it can enter into the constitution than what is rendered soluble by its combination with acid in the stomach. Too large doses of magnesia, however, are mischievous in another way, by causing the formation of magnesian calculi in the intestines. These are composed of magnesia mechanically blended with the faeces and intestinal mucus. They are not uncommon in these times, when so many individuals are in the habit of taking magnesia in a careless and profuse manner. I have, in several instances, known a person to suffer a good deal of distress from such a calculus being lodged in the rectum. But cases have occurred, in which the accumulation of magnesia in the intestine has taken place to a very great extent. Mr. Wilson examined the body of a patient, in whom, if I recollect rightly, many pounds of magnesia were found col- lected in the colon, above a contracted part of the rectum. In the exhibition of alka- line remedies, then, you must make each case the subject of a distinct experiment. * * * You should be provided with paper coloured blue by an infusion of litmus, and also with the same paper, slightly reddened by immersion in a very weak acid. Healthy urine ought to turn the blue litmus paper red ; and you should avoid giving alkaline remedies in such a dose as to destroy this property altogether; still less ought you to render the urine alkaline. If the urine turns the paper blue, the patient is in danger of suffering from a deposition of the phosphates and the alkalies must be given in smaller quantity."—(pp. 202, 203.)] The following are the excellent remarks of Prout on "the treatment to be adopted in what is usually denominated a fit of the gravel. " A Fit of the Gravel consists in the secretion of a large portion of lithic (uric) acid by the kidr\ey, under the circumstances above-mentioned, and is usually preceded, as well as accompanied, by much constitutional derangement, with tendency to fever and inflammation. The principles of the treatment to be adopted in this form of the disease closely resemble those recommended in gravel, except that they must be more active. When the attack is acute, venesection or cupping from the region of the kidney, with active doses of calomel and antimonial powder (or omitting the latter, if nausea be present, and substituting opium or hyoscyamus) should be imme- diately had recourse to, and precede the use of diuretic remedies. [Note.—I have seen great mischief done by the incautious use of stimulating diuretics at the commence- ment of the attack. The sufferings of the patient have been all aggravated, and his life has been placed in extreme danger.]—When these have begun to operate sen- sibly upon the system, though, perhaps, before the purgatives have produced actual stools, the patient may have recourse to warm fomentations about the region of the kidneys—or, what is much better, the warm bath, and commence the use of the diuretic purgatives formerly mentioned, with the addition of colchicum.- and these means, if judiciously and vigorously applied, seldom fail of removing the inflamma- tory spasmodic action of the kidney, and of producing a flow of urine. If the attack has been taken in time, the formation of a calculus in the kidney will thus be cer- tainly prevented; or, at least, what is formed will be very small, and scarcely ever fail to be brought away without producing those distressing symptoms which usually accompany the descent of a calculus down the ureter. It need scarcely bp men- tioned, that a strict antiphlogistic regimen is to be adopted; and that the collateral and subsequent treatment must be regulated by the symptoms present." (pp. 151, 52.) Jones, speaking of the treatment of the uric acid diathesis, in correspondence with Liebig's views, observes, that "exercise which produces perspiration is the most beneficial; and this the more so, the colder the air is, because thereby a greater amount of oxygen is absorbed ;" but it should be taken, "always stopping short of great fatigue, which might depress the vital powers, so as to admit of the produc- tion of an excess of uric acid." * * * Sleep, tending as it does to render the respi- rations as light and as few as possible, should be indulged in only as far as is ne- cessary to repair the fatigue which exercise has produced. Hot rooms should be avoided. * * * Nitrous oxide water, known also as oxygenated water, is the best diluent in these complaints. Soda water very rarely contains any alkali, but con- sists of ordinary water with carbonic acid forced into it; so that, except for the quan- tity of water, it is in no way beneficial; and in this respect it is not so good as TREATMENT OF. 261 ordinary fountain water, inasmuch as the atmospheric air suspended in the latter is better lhan the carbonic acid in the former. * * * By the various preparations of iron we may also increase the amount of red particles in the blood, and thus influence the quantity of oxygen which is absorbed. Perhaps the greatest practical benefit has been derived from the sesquioxide of iron." It should " not be given in the enor- mous doses recommended, by which the whole intestinal canal becomes loaded; but in moderate doses, and in such a state as we know offers the least impediment to its absorption; that is, in the minutest state of subdivision. To effect this, it should be given newly precipitated from some soluble salt of iron; as, for example, from the sesquichloride or persulphate of iron, from which hydrated peroxide of iron may be formed by the addition of carbonate of ammonia or soda." (p. 34-6.) "With regard to the treatment by diminishing the non-nitrogenous principles in the blood," Jones observes:—" It has been shown that the substances which contain no nitrogen, by combining with the oxygen which has been inspired, hinder the ac- tion on the uric acid ; and it is highly probable, that no albumen undergoes meta; morphosis until it has served the purposes of life. These are the first principles by which the practice must be governed; and hence, by far the most beneficial diet is a moderate quantity of meat, with a much smaller quantity of bread. The kind and quantities of both must be regulated by experiment and consideration of the habit and exercise of the patient. The quantity of starch in flour, as compared with ani- mal food, renders it unsuitable to live only on bread. Meat alone would be far more beneficial. * * * Sugar and starch comprehend much the largest part of those substances in vegetables which can be absorbed; nitrogenous and oleaginous sub- stances are present generally in small quantities, though the relative amount of these principles varies much in different species. Thus potatoes and rice are those in which most starch is found, and these are therefore most inadmissible; whilst in greens and peas there is much nitrogenous matter, which in peas is similar to cheese. Fruits usually contain large quantities of starch and sugar; on this account, apples and pears are most objectionable. * * * Among non-nitrogenous substances fat must be included. If the formula for .this is taken, as C 11, H 10, O, then 31 equivalents of oxygen are required, in order to convert this into carbonic acid and water; and by taking this substance as food, so much oxygen is prevented from acting on the uric acid. Butter is only the fatty particles of milk, separated from the albuminous and watery parts; this must on no account be taken in excess. Gelatine may be used as a partial substitute for meat; but as the albuminous tissues cannot be formed from it, it cannot be entirely substituted for it without the strength failing. "For drink the oxygenated water has been mentioned as best; then water which has been distilled, and therefore contains no substances whatever in solution, and on this account it is, generally speaking, the best solvent; that is, it can hold more in solution, and remove more from the body than another water which, when drunk, already contains substances dissolved in it. But this cannot be procured every where, and, therefore, it is desirable to point out how the best drinking water can be obtained." Filtering, or boiling water, or getting rid of the free carbonic acid gas by adding a little more lime, according to Reid's plan, are inefficient, and neither of the latter "causes any other salts of lime which rnay be dissolved in the water to be precipitated. To effect this, a few grains of carbonate of potash or soda should be added to the water before boiling, and the boiling should be continued for some minutes. By this means these salts of lime will be decomposed, and sulphate of potash and soda, or chloride of potassium and sodium, in very small quantities, will exist in the water after it has been filtered, or the chalky sediment has been allowed to settle to the bottom. Good fountain water or soda water are far better than beer and wine, which are objectionable for the spirit and sugar which they contain. The spirit is a substance which may be represented by C 4, H 6, O, and the sugar by C 12, H 14, 0 14, the first requiring 12 equivalents of oxygen, and the last 24, to convert them into carbonic acid and water. The excess of sugar and acid in home- made wines renders them more injurious than foreign wines or spirits, of which o-in and whisky most certainly also retard oxygenation, yet, by producing an excess°of water in the urine, they cause that deposit which arises from the want of action of the oxygen to be dissolved, and thus the evil which they and other substances occa- sion is for a time concealed, (p. 37-41.) " We can also diminish these non-nitrogenous bodies in the blood by aperients Vol. hi.—23 262 CYSTIC OXIDE GRAVEL, which act on the liver. These will be found more particularly useful when the de- posit is dark-coloured; indeed, the deeper the colour the less action there is of the liver. * * * Of such medicines calomel, aloes, colchicum, and colocynth are bene- ficial, both in large and purgative doses, and also when given in such a way as to increase the secretion of the liver. Hence the efficacy of blue pill as an alterative. * * * The use of these medicines as purgatives must be judged of by their effects and the strength of the patient. * * * Sudorifics are occasionally given with great advantage. * * * With regard to baths generally their action may be considered to be on the nerves and on the blood, and on each the action is of two kinds; thus on the nerves there may be a stimulant or sedative action, and on the blood they are capable of removing substances from it, and of enabling them to be absorbed into it. These modes of action depend on the state of the system, the temperature, and the substances which are dissolved in the bath. (pp. 41, ii.) "The next point in the treatment that must be attended to is to keep all the uric acid in the ultimate textures in solution. This may perhaps be effected by water and alkalies. When these or their carbonates are given, they should be taken at least an hour before food in order that they may not interfere with digestion; but though these medicines may relieve the complaint, they never can cure it. * * * I believe these medicines are the least necessary part of the treatment I have laid down, and it would be well for all to try what may be effected by diet and exercise, before they resort to alkalies, which may in some cases, perhaps, be the cause of an increase in the quantity of uric acid. This appears to be the opinion of Pelouze, in his last report." (p. 45.)] 2013. Gravel which is formed of cystic oxide requires the same treat- ment as uric acid, especially in reference to dietetics (1). In oxalate of lime gravel all vegetable food should be withheld, according to Magendie, but according to Prout the treatment must agree with that for uric acid gravel. After what has been already said (par. 1993) of the origin of gravel from oxalate of lime, both modes of treatment may be proper (2.) In phosphate of lime gravel the increased constitutional irritability in general, and that of the urinary organs in particular, must be diminished by opium, by hyoscyamus, and the like, in combination with tonic remedies. At the same time acids, especially the hydrochloric, must be used, and if that cannot be borne, citric or carbonic acid. Much drinking, which is usually recommended to favour the solution of the phosphates, is in reality hurtful, and increases the already too great irri- tability of the kidneys and bladder. In the use of acids, however, it must be remembered that if the patient use more than is necessary for neutralizing the alkaline condition of the urine, and for dissolving the earthy salts which are deposited, the white gravel indeed disappears, but, in its stead, uric acid gravel is formed from the precipitation of the uric acid, in consequence of the acid state of the urine. The bowels should be kept open with gentle, but not saline medicines ; the living should be strictly attended to: the patient should take easily digestible meat, light puddings, which seem more proper than the use of vegetables, and food destitute of azote, although, according to Magendie and Chevreuil, the phosphates are diminished in the urine of camivora by such diet. If any organic disease of the urinary passages or of the spinal mar- row accompany phosphatic gravel, a proper treatment should be had recourse to. [(1) With Tegard to the medical treatment of the sediment from cystic oxide, Prout observes, that it " will depend on circumstances. In the first place, great care should be paid to the digestive functions, and if the urine be acid, the alkalies maybe taken with advantage ; on the contrary, if alkaline, the muriatic acid, indeed the latter, if the irritation present would permit it, might, perhaps, in all cases be TREATMENT OF. 263 employed advantageously, not only with the view of retaining the cystic oxide in solution, but of inducing the lithic (uric) acid diathesis. From the diseased state of the kidney, also, with which this diathesis seems to be so frequently associated, local counter-stimuli will be likely to be serviceable." (p. 169.) (2) "The absence of urinary sediment, &c." in the oxalate of lime diathesis, says Prout, " are of a negative character, and lead to no inference where other circum- stances are wanting, as is most generally the case. But if there be pain in the region of the kidney, and other symptoms of gravel, without any appearance of sediment, and if the urine be acid and of the yellow tinge above alluded to, the stomach deranged, and an inflammatory diathesis, either general or local (i. e. about the urinary organs,) be present, and if all these are associated with suppressed gout, or tendency to cutaneous disease, the existence of this form of the disease may be suspected, and means immediately taken to counteract it. Besides the general principles of treatment above mentioned, I have lately adopted another principle, very different indeed from these, but which I think I have seen of considerable utility in two or three instances. This has been to endeavour to change the diathesis from that of the oxalate of lime to ihe lithic acid. It struck me that, as these two diatheses never appear to exist at the same time, if the former could be converted into the latter, that a very obscure disease would thus at least be exchanged for one of a more open character. The muriatic (hydrochloric) acid was chosen to effect this purpose, (though in some instances it is probable that the vegetable acids would answer as well,) and its use was continued till the lithic (uric) acid began to be deposited plentifully on the cooling of the urine. The muriatic (hydrochloric) acid is sometimes apt at first to derange the stomach, but notwithstanding this, in the few instances in which I have had an opportunity of adopting this plan, it has been always ultimately followed with very considerable relief to the patient's sufferings, both constitutional and local. * * * It need scarcely be mentioned that this plan of treatment requires some judgment and care in its management, and that it should hardly in any case be adopted when disorganization or calculus is already supposed to exist in the kidney or bladder, or perhaps in very young or very old subjects." (p. 160-62.) " In the oxalic acid diathesis," observes Jones, "the oxydizing process is carried a step further than it is when the uric acid diathesis exists; but it is still stopped short of the extent to which it is carried in the state of health. * * * It is possible that sugar and perhaps other substances of the non-nitrogenous class, may, by im- perfectly combining with oxygen in the body, give rise to oxalic acid ; still the oxygen has evidently a much stronger affinity for the non-nitrogenous than for the nitrogenous substances in the body, and thus the process of oxydation is far more frequently incomplete in the latter than in the former; so that we should expect oxalic acid generally to arise from the insufficient oxidation of the uric acid, and much more, rarely from sugar ; and the alternation of this substance with uric acid in calculi, and the ease with which it is formed from uric acid, leads to the belief that this is the usual origin of oxalic acid. The free oxalic acid passing off by the kidneys, meeting with the phosphate of lime, which is secreted both by them and by the mucous membrane of the urinary passages, decomposes it, and oxalate of lime is the result. The same thing happens when oxalic acid is taken, as such, in the food; if free, like tartaric acid, it passes off at the kidneys, and combines with the lime which it afterwards meets with. If taken in combination with alkalies, like tartaric acid, it would probably be decomposed. The causes, then, of this disease are in most cases similar to the causes of the uric acid diathesis ,- both dis- eases may be referred to insufficient oxidation, and the treatment must consequently be the same in both." (p. 71-3.) " It is highly probable that an excess of lime in the system may induce the forma- tion of oxalic acid, but some lime is necessary for the bones and the membranes, and it is taken into the system in all solid and liquid food. Now, though it is im- possible to obtain food absolutely free from it, and thus to hinder all formation of fresh oxalate of lime, still by rendering it as free as possible, the rapid increase of a calculus may be prevented. Perhaps of all substances, water is the easiest to render pure, and it is that which usually contains most lime. On this account, in the oxalic acid diathesis, distilled water should always be used in every thing for which com- mon water is employed in the state of health. When distilled water cannot be obtained rain water would be the best substitute; and when this is not to be had, 264 CYSTIC OXIDE GRAVEL, TREATMENT OF. then that which has been purified as already mentioned. *' * * This treatment is merely palliative, and the curative treatment must be directed to the oxalic acid and not to the lime." (p. 74.) (3) "The principles of treatment in both forms of the phosphatic deposit are," says Prout, " the same, and differ only in degree. The particular indications of cure seem to be to diminish the unnatural irritability of the system, and to restore the state of the general health, and particularly of the urinary organs, by tonics, and other appropriate remedies. In severe affections, especially of the amorphous class, opium, as far as my experience has hitherto extended, is the only remedy that can be employed with much advantage to fulfil the first indication. This must be given in large and repeated doses, such as from gr. i. to gr. v., or more, two or three times a day. Under this plan the more distressing symptoms will commonly be speedily relieved ; and now, in conjunction with opium, (in more moderate doses if the state of the disease will permit,) the mineral acids, cinchona, uva ursi, different prepara- tions of iron and other tonics may be had recourse to; or if the mineral acid should disagree, the citric acid may be taken instead. There may be also applied to the region of the loins, a large pitch, soap, or galbanum plaster, which frequently seems to afford considerable relief to the distressing pain there felt; or if the symptoms are unusually severe, and connected with manifest local injury, setons, or issues, may be instituted in the back. * * * rJ he bowels are most frequently constipated ; but purgatives of the more active class must be given with caution. Saline purga- tives, more especially those containing a vegetable acid, as the Rochelle salts, the Seidlitz powders, &c, must be avoided, and recourse had to small doses of castor oil or laxative injections. Mercury, in all its forms, and particularly when pushed so far as to produce its specific effects on the constitution, seems capable of doing a great deal of mischief, when the phosphates are concerned, more especially in the severer forms of the affection; and if from other causes it be judged proper or necessary, as the least of two evils, to administer this remedy, its exhibition must be managed with caution, and its effects closely watched. Perhaps the best mode of exhibiting it in such cases is to combine it with opium, or with a purgative, in some instances. I cannot help thinking, however, that in very severe forms of the affection, its use had better be omitted altogether, till the more distressing symp- toms have somewhat yielded, and the patient has recovered a little strength. Alka- line remedies of every description must be most carefully avoided, their use, in every point of view, being most mischievous, when the phosphates are concerned. Indeed, all remedies that act as diureties, should, in general, be shunned, and the patient should be prohibited from drinking too much. With respect to drinks in general, they should be of a soothing demulcent character, and prepared with dis- tilled or the softest water that can be procured, as hard waters are literally poison in this form of disease. In less severe cases, where the source of irritation is chiefly confined to the urinary organs, and where the constitution is sound, and the strength not remarkably reduced, similar means may be had recourse to: though opium, to the above extent, is seldom necessary or proper. In such cases, the hyoscyamus is an excellent remedy, especially when combined with the extract of uva ursi; and more or less, according to circumstances, of the extr. opii ; the same is true of the alchemilla arvensis, a strong infusion of which taken frequently, sometimes gives great relief. In such cases, also, occasional purgatives, especially of the milder class, may be employed with safety and advantage, (p. 182-86.) " The diet in severe cases should be of the mildest and most nutritious kind, and taken in very moderate quantities at a time. From what I have seen I am certainly inclined to advise an animal diet in preference to an acescent vegetable diet, com- monly recommended ; but I wish it to be understood that no positive directions are given on this point; * * * for I am disposed to believe, that in all instances, that diet is most proper for a patient, which agrees best with him, and which, in many instances oan be only known by actual trial; I may give it, however, as my opinion, that all watery diet, as soups, &c, should be taken very moderately. If the patient has been accustomed to wine, the Rhine or some of the lighter varieties of French wines will be preferable. Cider and perry may be also taken, if they do not disa- gree. I wish it to be understood, however, that the use of these is not particularly recommended. But these and every thing else that can be done for a patient in this state, are of very little use, if the mind cannot be set at rest. The influence of men- tal anxiety is really astonishing in this disease; and absence from care, the exhila- STONE IN THE KIDNEYS. 265 rating air of the country, and such exercises as are consistent with the patient's con- dition, will, perhaps, more than any thing else, contribute to the cure, particularly in the slighter cases, and when the cause is not local injury." (pp. 186, 87.) Jones observes that, in the palliative treatment of these complaints, "the first object must be to cause the phosphates to be retained in solution: this is effected by rendering the urine acid, which is most easily done by any vegetable acid, as tartaric, citric, acetic acids. It was found by the experiments of Woehler on men and dogs, that if any of these acids are taken in a free state, that is not in combination with an al- kali, they pass through the blood unchanged, and appear as acids in the urine. Why they should not be oxidized, as they are when in combination with alkalies, is at present unknown. * * * The dose of these acids should be gradually increased till the urine becomes again acid to test paper, when great care must be taken not to render it so much so as to cause precipitation of uric acid. * * * It has also been found, by experiment (a), that the strong mineral acids possess no power to render the urine acid ; probably their strong affinity for the soda in the blood causes it to leave its combination with the albumen ; and thereby salts of soda would be formed, and the acids would pass off by the kidneys as neutral salts. * * * Our chief at- tention must be directed to the removal, if possible, of the cause of the alkalescence which constitutes the curative treatment; this may be most beneficially joined with palliative measures. If the alkalescence arises from the altered mucus thrown out by an inflamed bladder, when the inflammation is cured, the acidity will return, the deposit cease. If the irritation of a stone causes the secretion of mucus or hinders the emptying of the bladder, the stone must be removed. If the alka- lescence proceeds from weakness, it is only by restoring the general health that the urine will permanently regain its natural condition; though for a time, and for a time only, much evil may be hindered by the use of vegetable acids." (p. 86-8.) II.—OF STONE IN THE KIDNEYS. (Calculus Renalis, Lat.; Nierenstein, Germ.; Calcul Renal, Fr.) Hevin, Recherches historiques et critiques sur la Nephrotomie; inMem.def'Acad. de Chirurgie, vol. iii. p. 238. Troja, Ueber die Crankheiten der Nieren und der ubrigen Harnorgane. Leipzig, 1788. Combaire, J. N., Dissertat. sur l'Extirpation des Reins. Paris, 1804. 4to. Earle, Henry, On Renal Calculi; in Med.-Chir. Trans., vol. xi. p. 211-18. 2014. In the calices and pelvis of the kidney, stones may be formed of different shape and nature, singly, crowded together, or as one very large mass, distending the cavities of the organ, in which case the sub- stance of the kidney is diminished by absorption. The chemical nature of renal stones varies; they most frequently, however, are composed of uric acid. [In rare cases, a stone in the kidney, if very large, may be felt through the loins. A case of this kind occurred to the elder Cline, who would have operated had the patient's health permitted (by Prout accounts for the formation of uric acid stones in the kidney in the follow- ing way:—" The kidney is made up of a congeries of similar parts, or little kid- neys, if we may use the expression, each one of which is independent of the others in its structure, and may therefore, probably, independently of the others, become more or less deranged in its functions. Let us suppose one or more of these little kid- neys similarly deranged to the others, but in a greater degree, so as to secrete very little water, but a large proportion of lithic (uric) acid. In such a case, the lithic (uric) acid must be obviously separated in that peculiar semifluid condition, (a) Berzelius's Handbook, p. 467. (b) A. Cooper's Lectures, vol. ii. p. 222. 23* 266 STONE IN THE KIDNEYS, DIAGNOSIS or state of hydrate, which it is well known to be readily capable of assumrog. In this state it is bulky, and may thus occupy the whole of the infundibulum in which it has been deposited ; or the quantity may be supposed to be sometimes so great as to be partly protruded, in a similar state, into the common receptacle or pelvis of the kidney. After remaining in this state for a greater or less time, crystallization may be supposed to take place ; the semifluid mass will now be much diminished in bulk, and perhaps reduced to the form of a congeries of crystals easily separable from one another, and thus pass off in the form of gravel; or what may easily be supposed to take place, (especially when the lithic aeid is very impure, and com- bined with a larger portion of the other matters than usual,) it may assume the form of an imperfectly crystallized or amorphous mass, and thus constitute a nu- cleus possessing these characters: or something between the two extremes may take place—the plastic mass may separate partly into crystals, and partly remain an amorphous mass, enveloping these erystals; in which ease, a mixed kind of nucleus will be formed." (pp. 207, 208.) Brodie (a) observes, that uric acid stones oecur "most frequently in those who have led luxurious and indolent lives; and who previously have been subject to de- posits of lithate of ammonia, or of lithic aeid sand, in the urine. It is this class of individuals that is especially liable to gout, and there is an evident connexion be- tween these two diseases. A patient may have been in the habit of voiding lithic (uric) acid calculi ; he becomes affected with the gout, and the formation of the cal- culi ceases. In a few cases the two diseases go on together. Some persons void a great number of this kind of lithic acid calculi. I am almost afraid to say how many I have known to be voided by one individual—probably some hundreds, of all varieties of size." (pp. 224,25.) "I have had fewer opportunities of examining renal calculi composed of oxa- late of lime," says Prout, " from their being comparatively more rare. Sometimes they are formed on a primary nucleus of lithic (uric) acid. In one or two instances, I have seen them contain in their centre an irregular cavity, formed apparently by the agglutination of several imperfectly globular-shaped plastic masses round a sub- stance which had subsequently been entirely remo ved,or had disappeared by drying; the whole being afterwards surrounded by concentric laminae of the same substance. It may, perhaps, appear difficult to conceive how a substance so insoluble as oxalate of lime can exist in a plastic state, or form a calculus at all; since, in our hands this salt occurs only in the state of a powder, and seems incapable of concreting or as- suming the crystallized form. Perhaps the circumstance may admit of an explana- tion, by supposing that a solution of oxalic acid, nearly in a saturated state, and in union with a little lime, is secreted by a portion of one of the kidneys, instead of the lithic (uric) acid in the former case; that this, enveloped in the usual ani- mal matters, passes from the infundibulum into the pelvis of the kidney, and there meeting with the lime naturally contained in the urine seereted by the other parts of the kidney, instantly combines with it, and forms the compound in question; and that from the peculiar manner in which it is formed, and the abundance of animal matters present, it may be able to exist for some time at the temperature of the hu- man, body in a plastic semifluid state, before the whole concretes into a solid mass. Whether this supposition be admitted or not, which is a matter of no importance, the facts are certain, that oxalate of lime not only does sometimes exist as an amor- phous mass in renal calculi, but occasionally in the form of crystals also ; a circum- stance still more difficult to explain, except on some such supposition as the above." (pp. 209, 210.) Brodie also observes :—" Calculi of oxalate of lime are much more rare than those of lithic (uric) acid. It is not merely that the disposition to form them exists in fewer individuals, bat that where it does exist they are not generated in the same number as the lithic (uric) acid calculi. A patient may void one of these calculi, and never void another, or he may void a second after the lapse of many years. In one instance, however, in examining a body after death, I discovered as many as five or six in one kidney : extensive suppuration and complete disorganization of the glandular structure of the kidney ; and this local disease was the immediate cause of death." (p. 225.) (a) Above cited. AND TREATMENT. 267 "Calculi of cystic oxide," Prout states, "are extremely rare. From what has been already quoted on this subject, there is reason to conclude that they generally originate in the kidneys. I have only had an opportunity of examining two speci- mens of this species of calculi, with reference to their primary nuclei; in one of these the nucleus consisted of a small triangular amorphous mass, apparently of the same matter as the rest of the calculus, though a little deeper coloured. In the other, no distinct nucleus could be discovered." (p. 210.) The rarity of renal stones composed of the phosphates, Prout considers as de- pending "on various circumstances. In the first place, this form of the disease is seldom original, but consequent to others; and the system appears to be affected generally, rather than the kidney locally, as in the other forms of the disease. In the second place, the large flow of urine, and the consequent hurried state of action to which the kidneys are necessarily subject, may be justly considered as unfavour- able to the formation of renal calculi. In some instances, however, as before stated, calculi composed of the phosphates are actually formed in the kidney; but in every instance of this description, the particulars of which I can trace, it has occurred only in very severe and obstinate cases of the phosphatic diathesis." (p. 211.) 2015. The diagnosis of renal stones is for the most part doubtful, as the symptoms which they produce are very various. Sometimes they cause no pain; often (he patient feels an oppressive, dull, straining pain in the region of the kidney, which sometimes ceases and then recurs, is diminished by rest, and increased by jolting movements of the body. With pointed, angular stones, the pain is severe and tearing, extending towards the groins and testicles. Not unfrequently inflammation of the kidneys occurs with all its symptoms. The urine is often mixed with blood, mucus, pus, and sand. ["Sometimes," says Brodie, "calculus in the kidney may be said to cause no inconvenience at all, so that calculi are found in the kidney after death, the exist- ence of which had never been suspected during the patient's lifetime. In other cases, the patient complains of pain in the loins, and the urine is occasionally tinged with blood, especially after any jolting exercise, such as riding on horse- back." (p. 233.) Astlev Cooper observes, that "the presence of a stone in the kidney is some- times manifested by extreme irritability of the bladder," of which he mentions an instance, in a male, that had existed for a great length of time without being relieved by treatment. After death, "no disease of the bladder or urethra was found, but a large stone was discovered in the kidney." (p. 221.) Brodie relates a similar ex- ample in a female, but in this case, "the urine deposited what appeared at first to be a muco-purulent secretion, but afterwards had all the characters of true pus, like that from an abscess." After two or three years, symptoms of a stone passing through the ureter came on; a large stone was voided by the urethra, and the origi- nal symptoms were relieved, (p. 68.)] 2016. Stone in the kidney is a tedious and painful disease. If only one kidney be affected, there is less danger to life than if stone exist in both kidneys. If inflammation of the kidneys arise, it may cause death by its severity, and by the complete suppression of the urine, or it may go on to suppuration, and the pus may be discharged either by the ureter, or it may form a fluctuating tumour in the loins. ["In the majority of cases," says Brodie, "a calculus of the kidney finds its way into the bladder soon after its first formation; but in other cases it remains for a considerable time in the kidney, being at last dislodged by some accidental circum- stance;" of which he mentions a good example, of a gentleman whose urine had been occasionally tinged with blood; having been overturned in a carriage, he soon after found himself unable to make water, but after some straining, a renal calculus which seemed to have the form of one of the infundibula of the kidney, was pro- jected with no small degree of force, and the urine flowed in a full stream " (n 233.) ^' 268 STONE IN THE KIDNEYS; TREATMENT. Instances of abscesses in the loins, by which stones from the kidney have been either extracted or discharged, are mentioned by Hevin (a), and Astley Cooper, in whose patient they were composed of the ammonia-magnesian phosphate (b). Brodie also mentions the case of a woman who had abscess in the loin, which after death was found communicating with a large collection of irregular-shaped stones in the kidney (c). A stone remaining in the kidney may be snapped in two by the person making use of any unaccustomed exertion, of which my friend Crisp has mentioned to me the following example:—A medical man whilst jumping over a flower bed, dropped down suddenly with intense pain in the loin, which continued for two or three hours. He died a few months after of heart disease and other lesions, and on examination of his body, a stone was found in the kidney of irregular oblong form, which was separated transversely into two nearly equal halves.—j. f. s.] 2017. The treatment, when the object is the solution of the renal stone, or the getting rid of the disposition to lithogenesis, must be guided by the rules already laid down {par. 2011-13.) It is in general confined only to lessening the symptoms, by blood-letting, mild mucilaginous drinks, antispasmodic remedies, baths, rubbings and the like (1). The removal of the stone by cutting (Nephrotomia) can only be under- taken, when an cedematous, or fluctuating swelling, or a fistula has formed in the loins. Having opened the abscess, its bottom must be examined with the finger or the probe, and if a stone be met with it must be removed, after enlarging the wound, if it be too confined. If there be a fistula leading down to a stone, it must be properly enlarged with sponge tent or with a bistoury. If the stone be fixed, its extraction must be postponed till it has become somewhat loose. Oftentimes a superficial suppurating cavity is found between the muscles and the skin, from which an opening leads to the abscess in the kidney. The wound, whether or not a stone be found, should be kept open with wads of lint attached to a thread, as long as stones are formed in the kidney, or the diseased secretion exists in the urine (2). [(1) "If there be symptoms," says Brodie, "which lead you to suspect that a stone is lodged in the kidney, it is of course desirable that it should be made, if possible, to pass into the ureter, before it has attained such a size as to be incapa- ble of being conveyed along the canal into the bladder. Horse exercise, especially hard trotting, in such a case generally produces bloody urine. This shows that the calculus is made to undergo some change of position, and whatever produces this effect, is, of course, favourable to its escape from the kidney.—[With due respect to this high authority, I should hesitate in advising horse exercise, or any other vio- lent effort to excite change of place in the stone, for fear of setting up active inflam- mation in the kidney, already irritated by the pressure of stone, and which might not be very easily or certainly repressed.—j. f. s.]—It is reasonable to suppose, that medicines which occasion a more abundant flow of urine, combined with diluting drinks, may also be useful under these circumstances. Where a calculus retained in the kidney produces considerable pain in the loins and neighbouring parts, the patient will sometimes derive benefit from local blood-letting, by cupping, or by leeches. At other times the application of the belladonna plaster. You may also employ setons and issues in the loins, as recommended by Earle (d). According to my experience, however, the last-mentioned remedies are seldom very useful, except in those cases in which disease of the kidneys, and especially abscess of the kidney, has taken place as a consequence of the lodgment of the calculus. That they are sometimes eminently useful, under these last-named circumstances, I can- not doubt." (p. 241.) "When the inflammation of the kidneys is supposed to be connected with the (a) Mem. de l'Acad. de Chirurgie, vol. iii. (c) Above cited, p. 69. p. 266. (d) Med.-Chir. Trans^ vol. xi. p. 211. (6) Lectures, vol. ii. p. 222. STONE IN THE URETERS. 269 presence of renal calculi," which is by far the most frequent occurrence, Prout re- commends, "in connexion with general blood-letting or cupping (if necessary) and the warm bath, calomel in active doses, which, when the constitution is otherwise sound, may be employed with great advantage, especially if it be immediately fol- lowed or accompanied by the use of hyoscyamus in pretty large doses, so as to insure the anti-spasmodic effects of the latter on the system; and when the urine is high- coloured and acid, the purgative effects of the calomel may be increased or kept up by the use of some of the diuretic purgatives, such as the neutral salts, and particu- larly the tartarized soda. This plan may be pursued for a greater or less time, according to the circumstances of the patient; and will, in favourable cases, be followed by the expulsion of the cakulus from the kidney, without the severe symptoms commonly accompanying its descent down the ureter." (pp. 219, 20.) (2) In connexion with the subject of stone in the kidney, the following observa- tions of Brodie on what he considers to be Gouty Inflammation of the Kidney are worthy of particular notice. "A class of cases you will occasionally meet with," says he, "among the affluent classes of society, the symptoms of which bear no small resemblance to those just described, although they have a very different origin; and the diagnosis of which is of no small importance in practice. The persons liable to be thus affected are those who lead indolent lives, indulging themselves, at the same time, in all the luxuries of the table. There is pain in the loins, often very severe, extending downwards to the groin; the urine is scanty and high coloured, depositing, as it cools, an abundant red or yellow sediment (lithate of ammonia.) So far the symptoms a good deal resemble those produced by the passage of a calculus down the ureter; but the ab- sence or pain in the testicle, of siekness and faintness, and the presence of no small degree of symptomatic fever, enable you to distinguish the two orders of cases from each other. The effect produced by the remedies will assist you in your diagnosis. The symptoms which have been just described are of a gouty origin, and yield almost immediately to a free exhibition of colchicum ,• which, however, it is gene- rally more prudent not to administer until after the bowels have been emptied, by the exhibition of some grains of calomel, followed by a draught of infusion of senna with the sulphate of magnesia, or some other saline aperient." (p. 232.)] III.—OF STONE IN THE URETERS. (Calculus Uretericus, Lat.; Stein in den Harnleiter, Germ.; Calculengage dans Vurelere, Fr.) 2018. When a stone descends from the kidney into the ureter, more or less violent symptoms arise, in proportion as the passage of the urine through the ureter is completely or partially prevented. Pain comes on which descends from the kidney to the pelvis, and the patient often feels distinctly the gradual progress of the stone. The ureter is often consi- derable distended by the urine collected above the stone. Symptoms of stone in the kidney will also have been previously observed. When the stone escapes from the ureter into the bladder, the symptoms quickly subside, and those of stone in the bladder arise (1). The treatment is precisely similar to that for stone in the kidney, and for ischuria ureterica (2). [(1) "The time occupied by the passage of the calculus along the ureters varies in different cases," says Brodie (a), " according to the dimensions and figure of the calculus, and the impulse which it receives from the current of urine behind it. Sometimes the calculus may reach the bladder almost immediately; at other times it may be lodged in the ureter for many hours, or even for two or three days. Where the passage of it is thus protracted, the parts to which the pain is sympathe- (a) Lectures in London Med. Gaz., vol. viii. 270 STONE IN THE URETERS. tically referred, become tender to the touch, and the testicle not unfrequently is actually inflamed and swollen, the inflammation of it continuing for some time after the cause which produced it had ceased to operate. * * * The pain is often very severe, and in that case attended with sickness and vomiting, prostration of strength, cold extremities, a feeble pulse, and a pallid countenance; in short the patient is what is commonly called in a state of collapse. These symptoms are followed by pain referred to the inside of the thighs and the testicle; and frequently the testicle is drawn upwards to the groin by a spasmodic contraction of the cremaster muscle; no relief is experienced until the calculus has escaped from the lower orifice of the ureter, and entered the bladder; but as soon as this has happened, the patient's tor- tures, for they truly deserve that appellation, are at an end. (p. 66.) It seldom happens that the excretory duct of the kidney is completely obstructed, but when it is so the necessary consequence is that the urine becomes accumulated in the infun- dibula, and that these become dilated to a large size, forming membranous cysts; while the glandular structure of the organ is expanded, and in a great measure ab- sorbed from the pressure which is thus exercised upon it. In some cases, you find at last the kidney converted into a large membranous bag, on the surface of which scarcely a vestige of the glandular structure is perceptible, while the interior of it is composed of a number of cells communicating with each other, and all containing urine." (p. 68.) "But a calculus (a) maybe of such size as to be stopped in its passage to the bladder, and retained in the ureter. One might suppose, that under these circum- stances, the ureter would become more and more dilated, and at last burst, as the urethra bursts behind a stricture. I cannot say this never happens; and indeed Morgagni quotes a case from another writer, in which there is reason to believe that such an event actually occurred. However, this is not the constant order of events, as the following case, which occurred to Brodie, will prove; a person for several years had been subject to the formation of renal calculi, which were passed by the urethra. At last, however, an attack came on, no stone passed, and he ceased to void urine; a catheter was passed, but no urine flowed ; the patient became coma- tose, and died ten or twelve days after." In one kidney there were several calculi; there were none in the other. In the latter and in the upper part of that canal, there was a calculus, as it were wedged in, of about the size of a horse bean. A patient died also under Travers's care, with the same symptoms, having each ureter where it arises from the pelvis of the kidney completely obstructed by a calculus." (pp. 241, 42.) Persons may also die from suppuration occurring in the kidney, whilst its escape is prevented by a stone blocking up the ureter. A case of this kind is related by Astley Cooper (b) as having occurred to the elder Cline; he had operated on a boy for stone in the bladder. "The boy had recovered from the operation, when he was seized with rigors, great pain in the course of the ureter, and vomiting; a swell- ing formed just above the seat of the caecum, in the right \\iac fossa, which gradually increased, and the boy's constitution quickly gave way. On examination after death, the pelvis of the kidney and the ureter were found distended with matter; and at the end of the ureter near the bladder, a stone was discovered, which had prevented the escape of the urine and matter into the bladder, and thus occasioned death." (p. 225.) He mentions also the case of a woman who "had great pain in her loins, and ten- derness in her abdomen, with so much fever, that she did not live long. * * * Upon making an incision into the abdomen, there issued a strong urinous smell, and a watery fluid mixed with matter. The intestines were inflamed and adherent; the bladder was small; one kidney was much enlarged, and the other unaltered; the ureter of the enlarged kidney was greatly increased in size, and full of matter; it was completely closed at the lower part by a calculus, and had given way above, so as to allow of the escape of the urine and matter into the abdomen." (p. 226.) He also relates one case in which a stone stopped for some time in the ureter, and the latter having become adherent to the colon, ulceration ensued, and the stone was discharged by stool; and another where "an abscess formed near the anterior supe- rior spinous process of the ilium from which a calculus and a quantity of matter were discharged, and the patient recovered." (p. 227.) (2) As to treatment, Astley Cooper recommends large bleeding, warm bath, (a) Lectures, at the head of this article. (b) Lectures, vol. ii. STONE IN THE BLADDER. 271 opium, liquor potassae, to allay irritation, and the abdomen to be fomented, and gently rubbed from above downwards to assist mechanically the passage of the calculus. (p. 227.)] IV.—OF STONE IN THE BLADDER. (Calculus Vesicalis, Lat.; Harnblasenstein, Germ.; Calcule Vesical, Fr.) 2019. Stone in the urinary bladder is either primarily formed in the kidney, and enlarges in the bladder, or it forms in the bladder, as in incrustations on foreign bodies. The variety of stone in the urinary bladder is very great, as regards shape, size, number, and position ; and on these, in part, depends the severity of the symptoms which it excites. [" Calculous disorders," observes Brodie, "prevail differently in different classes of society, among individuals of different ages, and in different climates and dis- tricts. Among the lower classes, children are much more liable to calculi than adult persons. You know how large a proportion of our hospital patients admitted for lithotomy are children. On the other hand, in private practice, that is, among the upper classes of society, very few of our patients are children, and the great majo- rity are persons above fifty years of age. Nor are these things of difficult explana- tion. The great majority of calculi are originally composed of lithic (uric) acid, that is, have a lithic acid nucleus. * * * In all classes, persons of a middle age are less frequently affected by stone in the bladder than those who are younger or older." (p. 253.) These observations are confirmed by the following analysis of three hundred and fifty-four cases, between the ages of two and of seventy-nine years, which has been given by Smith, of Bristol (a), together with the results of the operation, which was performed on all, seven only of the number being females, of whom two were under ten years, three between ten and twenty, one between twenty and thirty, and one between thirty and forty. Analysis of 354 Cases of Lithotomy. " 135 from 2 years to 10; Cured, 106; Died, 29, or one death in 4£ 65 10 20 52 13 5 35 20 30 30 5 7 34 30 40 27 7 5 37 40 50 26 11 H 28 50 60 22 6 41 18 GO 70 11 7 n 2 70 79 1 1 2 354 275 79 H Smith estimates the number of stone-operations in the provinces at 90; in the London hospitals, at 47; and in London private practice, at 30; making a total of 167: in the whole of Scotland, at 12; in Ireland, the same; and that, if we take the whole in round numbers at 200, we shall have the very extreme point of cal- culous cases for our whole population. He also notices the curious fact, that certain districts abound in cases ; whilst, in others, the disease is scarcely known. "Let us instance Norfolk and Hereford; and again, it is a surprising truth, that in the hospital at Norwich alone, the numbers are as great as either in all Ireland or Scotland." (p. 50-2.) Whilst in the County Hospital at Hereford there had not been a single stone-patient in the course of forty-five years. Sailors appear to be remarkably free from stone in the bladder, as from A. Copland Hutchinson's (6) (q) A Statistical Inquiry into the fre- (b) On the Comparative Infrequency of quency of Stone in the Bladder in Great Urinary Calculi among Seafaring People; Britain and Ireland; in Med.-Chir. Trans., in Med-Chir. Trans., vol. ix. 1818. vol. xi. p. 1. 1820. 272 STONE IN THE BLADDER; account, only eight cases occurred in the course of fifteen years in the navy, during which period the average annual number of men in the service was 132,000. And he asks two questions—-first, that it appearing "seamen, who have rarely oppor- tunities of indulging in the use of malt iiquors, are, in great measure, exempt from urinary concretions, whether all kinds of fermented liquors be not favourable to the production and accretions of such disorders!" second, "may it not, therefore, happen, in the instance of seafaring men, that the peculiarities of their regimen, and especially the great quantities of muriate of soda they habitually take with their food, contribute to produce this effect?" (p. 453.)] 2020. In regard to the form of stone in the urinary bladder, what has been already stated in general {par. 2005) applies here also. In most cases, especially when there is but a single stone, it is oval, and somewhat flattened on both sides; its surface smooth, bossed, or angular, and often wish facettes of various forms (1.) Its size usually varies be- tween that of an almond and of a hen's egg; it may, however, be much larger (2). In general, there is only one stone in the bladder; but, sometimes, several, even as many as a hundred, exist at the same time (3). In such cases, the stones, as already remarked, are, in some places, smooth, ground away, and variously formed, by lying against each other. According to their chemical composition, they vary in reference to their firmness, colour, and the like. In most instances, the stone lies loosely at the bottom of the bladder; but not unfre- quently it is attached at one place, which may occur in different ways. First. The stone sticks in the orifice of the ureter, or, in escaping from the ureter, it slips between the membranes of the bladder, and en- larges, so that it lies in a cavity of its own, which communicates with the bladder itself by a roundish opening. Second. It lies in a diverticu- lum of the bladder, or in a hernia of the bladder (4.) Third. In many persons the inner surface of the bladder has a peculiar net-like disposi- tion, by which fan-shaped hollows are formed; and if the formation of a stone begin in one of these, the hollow is gradually enlarged, and the stone is, for the most part, overspread by the internal coat of the bladder. In proportion as the stone increases, the enclosing mem- brane stretches, so that it is connected to the other part of the bladder merely by a neck (5). Fourth. Stones, which form in the prostate gland, may partially project into the bladder. Fifth. In consequence of the irritation of the stone, and the inflammation depending thereon, false membranes are formed by the exudation of plastic lymph, which partially cover the stone. Stones which are enclosed and held fast in one of the above ways {Calculi saccati, Lat.; Umschlossenen und festgehallenen Steine, Germ.; Calculs enchatonnes, Fr.,) must be distinguished from the so-called adhe- rent stones, (Calculi adherentes, Lat.; Angewachsenen Steine, Germ.; Calculs adherens, Fr.,) a term which can only apply to those cases in which excrescences, fungus, and polypi of the bladder become incrust- ed (a). [(1) In reference to those stones occasionally mpt with, and which being con- tracted in their middle, have somewhat the shape of an hour-glass, Taylor (b) ob- serves:—"It has been conjectured that in such cases they have been partly lodged (a) Houstet, Observations sur les Pierres —Deschamps, above cited, vol. i. p. 59-77.— enskystees et adherentes a la vessie; in Walther, above cited, p. 424. Mem. de l'Acad. de Chirurgie, vol. i. p. 395. (b) College Catalogue, part i. FORM AND SITUATION. 273 in the orifice of the ureter or in a pouch of the bladder, and that the growth of the calculus has continued unobstructed at the two extremities, while it has been pre- vented in the middle by the constriction of the orifice. But the deposition of qrys- tals, even on the constricted portion, seems scarcely consistent with this explanation, unless it is conceived that they were deposited after the calculus had escaped into the cavity of the bladder." (p. 83.) (2) The size of stones is very variable. The largest stone is, I believe, that from Sir Walter Ogilvie, which is in the College Museum H 2, consisting of mixed phosphates; it weighs forty-four ounces, measures sixteen inches around its long axis, and fourteen around its short axis. Its origin seems to have been traced to his having received a blow in his back from the boom of a vessel, when twenty-three years of age; in consequence of which it was necessary to draw off his water with a catheter for two months; and for a twelvemonth after he was obliged to keep in bed, in a horizontal posture; his bladder, however, recovered its powers. Twenty years after, symptoms of stone having appeared, and sounding having led to the belief in the existence of a large stone, the operation was advised, but not assented to. He continued to become worse, and towards the latter end of his life he could "make no water, without standing almost on his head, so as to cause the upper part of his bladder to become the lower, and this he was obliged to do frequently, some- times every ten minutes, as the quantity voided each time was less than the measure of a wine-glass. At last, however, thirty years after the accident, he was so worn out, he was determined to have the stone removed, which could now be felt above the pubes, forming a large prominent tumour, and below it prevented the entrance of a sound into the bladder. The operation was attempted by Cline, but no kind of forceps could be introduced till a soft part of the stone having been found, some of it was broken away with the finger, and then the forceps broke away more, till, with the aid of the scoop, about a teacupful of fragments was removed; but the greater part of the stone remaining hard and impenetrable, and Sir Walter being much exhausted, the operation was given up: he died on the tenth day. The stone appeared moulded by the bladder; the lower part confined by the bony pelvis, with its impression, and was smaller than the upper part, which had projected so as to lie on the pubes (a). Of stones which have been removed, Astley Cooper mentions one in Trinity College, Cambridge, which weighs thirty-two ounces and seven drams ; a cast in St. Thomas's Museum of one which weighed twenty-five ounces ; another of sixteen ounces which he himself removed, but without success; one removed piecemeal, by Mayo (b), of Winchester, weighing fourteen ounces and two drams, and measur- ing eight inches and a half in its smallest, and ten in its largest diameter; one in the Museum of the Norfolk and Norwich Hospital, of eight ounces. The largest stone removed successfully by Astley Cooper, weighed near six ounces. Smith (c) mentions a cast in the Bristol Museum, of a stone which weighed ten ounces and a half, and measured nearly ten inches in circumference : the patient recovered in eleven weeks. In the Museum of the College there is a stone, A c 7, composed of three large uric acid stones, cemented together with mixed phosphates, which weighs seventeen ounces: it was removed by Cheselden, in St. Thomas's Hospital, from a man fifty years of age, but he died the next day after the operation. As to the small size of stones, perhaps that of ten grains from ± lad of thirteen years, and that of a few grains from a boy of sixteen, removed by Martineau (d), may be considered among the smallest. (3) "The greatest number of stones I ever extracted in the operation of lithoto- my," says Astley Cooper, "was one hundred and forty-two, many of them about the size of marbles. A great number of stones does not add much to the patient's danger in the operation ; for it is not the frequent introduction of the forceps, but the violence which is used in extracting the stone or stones which produces mischief; thus the removal of one large stone, is more to be dreaded than that of many small." (p. 233.) (4) In the Museum of the College of Surgeons, there is a fusible stone which was removed by Pott (e), from a vesical rupture in a boy of thirteen. " When six (a) Taylor's Catalogue, part i. p. 116-19. (b) Med.-Chir. Trans., vol. xi. p. 55. 1820. (d) Med.-Chir. Trans., vol. xi. p. 407. (c) Ibid., p. 15. (e) Chirurgical Works, vol. iii. p. 324. Vol. hi.—24 274 STONE IN THE BLADDER ; years old he was seized with an acute pain about the region of the pubes, which lasted near an hour and a half, and suddenly ceasing he became easy. During the time his pain lasted he could not discharge a drop of water, though he endeavoured so to do, but as it ceased he pissed freely. In a few days after a small tumour was discovered, about the size of a pea, in the spermatic process just below the groin; it gave the child no pain, and therefore no notice was taken of it." When thirteen years old it became troublesome from its weight, though he had never any pain in his back and loins, and it was therefore determined to remove it. This was done by a cut through the skin and cellular membrane, the whole length of the process and scrotum, which exposed a firm white membranous bag or cyst, narrowing upwards, and being followed was found " dependent from and continuous with a membra- nous duct, about the breadth of the largest wheatstraw, or what it was more like to, a human ureter, which passed out from the abdomen through the opening in the muscle." On dividing this duct, immediately above the tumour, four ounces of a clear fluid issued, and the mouth of the cyst expanding, presented a stone similar to that found in the human bladder. To decide on the connexion of the cyst with the bladder, the boy was after some time directed to make water, when a large stream of urine flowed through the wound instead of by the urethra. He recovered. In the preparation the stone is enveloped in the cyst. (5) The case related by Brodie of " an elderly person, who for the most part suf- fered little inconvenience from the disease, but every now and then was suddenly seized with usual symptoms of stone and very severe ones too," seems to be of this kind, except, that it does not appear to have had any neck, which as far as I have had opportunity of seeing is very rare. He lived three or four years after the de- tection of the disease, and died of pleurisy. " On examining the body, I found," says Brodie, " the stone imbedded in a cyst near the fundus of the bladder. The cyst was formed in this case, not by the protrusion of the mucous membrane between the muscular fibres, but by a dilatation of both tunicles of the bladder, the muscu- lar as well as the mucous. It was such a receptacle as would be supposed a large calculus which had long been resident in the bladder, might gradually have made for itself. The stone was not so closely embraced by the cyst as to prevent it occasion- ally slipping out of it, and I suspect that this actually happened, and that it was when the stone lay in the cyst, that the patient was free from the usual symptoms of calculus, and that his sufferings took place when the stone escaped from it into the general cavity of the bladder." (pp. 258, 59.) (6) Wickham (a) relates the case of a boy four years old, on whom he performed the lateral operation, and met with some difficulty in extracting the stone; " no un- toward symptom occurred, until about the eighth day, when the water returned to its accustomed course, which was attended by severe pain, the boy screaming very loudly at each effort to make water. This continued till the fourteenth day, the wound having appeared foul and the surrounding parts inflamed for two or three days previously, when a substance came away from the wound, having the following appearance. It is a cyst, apparently of the same structure as the bladder; its size is sufficient to contain the calculus, which weighed two drams ; the opening into it is just large enough to admit of its exit, and its whole internal surface is lined with calculus matter, in fact, studded with large pieces of calculi. * * * I have no hesi- tation," says Wickham, " in pronouncing the substance voided by the wound to be a cyst, in which the stone was contained previous to the operation." (p. 186.) I cannot agree with Wickham's conclusion on this point, as he states (in describing the operation) that "the stone being completely exposed, he passed in the forcep9 again, and took away the calculus without difficulty," though he had done nothing more than dilating the gorget wound, which he thought had not been made sufficiently large by a very slight effort with his finger. I do not think the stone had been en- cysted, not even by a false membrane, as here described by Chelius, but it seems to me corresponding precisely to the following circumstances mentioned by Brodie: —" It occasionally happens, that coagulated lymph is effused from the inflamed mucous membrane of the bladder. The inflamed mucous membrane also secretes the adhesive mucus which contains the phosphate of lime. A portion of the phos- phate of lime thus produced, mixed probably with some of the triple phosphate from the urine, is deposited on the lymph, and thus the incrustation takes place. It cor- (a) London Medical Gazette, vol. iii. 1829. FORM AND SITUATION. 275 responds exactly to the incrustation of the wound of the perinaeum, which occurs aftsr lithotomy, where the operation is followed by the secretion of the same ropy mucus from the bladder." (p. 260.) Brodie speaks of " a class of cases which, being of rare occurrence, do not seem, in the present state of our knowledge to be of muchpractical importance," and quotes from a letter of Heister (a), "the history of a patient who, having for a considerable time, laboured under the symptoms of stone in the bladder, began to void by the urethra what had all the appearance of portions of a larger calculus, broken down into fragments of various shapes and sizes. The number of these fragments at last amounted to more than two hundred, and now the discharge ceased, the symptoms at the same time having subsided, and the patient being restored to perfect health. In this instance, the discharge of the fragments of the calculus was attributed to the use of certain mineral waters." Prout mentions a case, in which, however, the same happened without the patient using mineral waters or any kind of medicine; and Cross speaks of numerous fragments which he obtained from a gentleman after a ride on horseback; as well also " of twenty-two calculi removed after death, from a patient seventy years of age, which are of a very irregular shape, but admit of being so arranged as to form four regular and well-shaped calculi, each of the size of a pigeon's egg, which, with the appearance of the different surfaces, proves that the calculi had broken in the bladder by knocking against each other under certain movements of the body. The incrusted state of the fractured surfaces proves, that the calculi were broken some time- before the death of the individual." (p. 10.) Brodie, himself, has also seen three cases of the same kind ; in one, evident frag- ments of a larger calculus were voided by a young lady; in another, numerous small calculi were voided next day after a journey, which had the appearance of having been recently broken, probably from the concussion of them one against the other during the journey; and a third, in which after or whilst drinking some mineral waters, "he began to void with his urine broken pieces of calculi of various shapes and sizes, but generally with one concave surface, and rough irregular edges, as if the various laminae of which the calculi were composed had cracked, and then had become separated from each other. After some time a great number of these frag- ments having come away, the discharge of them ceased, the patient, being at the same time, relieved from all the symptoms under which he had formerly laboured." (p. 269-71.) In the Museum at the Royal College of Surgeons there are several examples of similar broken stones.] 2021. The symptoms of stone in the bladder are very various. In general when the stomach is primarily formed in the kidney, there is more or less severe pain in the kidney, and running along the ureter. This is wanting of the stone to be first formed in the bladder itself, and especially must not be considered as a certain and constant symptom. The patients have a sensation of warmth or painful tickling in the glans penis, and they, therefore, especially if children, are continually pulling the penis about and drawing it away from the body. These sensations show them- selves at the beginning of the disease, but only when the patient exerts himself violently, or the posture of his body is suddenly changed, or im- mediately after passing the last drops of urine. The orifice of the urethra is inflamed, as in a clap. The call to make water occurs very frequently, and whilst the water flows, there is a burning pain at the tip of the glans. The stream of urine is often suddenly interrupted; the most insufferable pain, occurs with severe forcing, and the urine only again begins to flow when the patient changes his posture, lies ou his back or the like. The discharge of the last drop of urine is attended with the most violent pain, as the bladder then contracts upon the stone. The call to make water is accompanied with frequent forcing at stool, and often to such degree that (a) Phil. Trans., vol. xxxvii. p. 13. 1731, 32. 276 STONE IN THE BLADDER J the rectum protrudes, and frequently the hsemorrhoidal vessels swell from the irritation of the bowel. The same also occurs in women, with the vagina, which in a long-continued state of irritation and inflammation, becomes the seat of constant mucous discharge, and often protrudes. The urine passed is generally pale, limpid, and has a peculiar offensive smell. If the patient keep quiet, the symptoms are usually slighter; but they increase on every movement, in walking, riding on horseback, or in a carriage, in which latter case the patient often feels as if a foreign body fell from one part of the bladder to another; after violent movements some drops of blood frequently flow from the urethra. The patient com- plains not unfrequently of a painful drawing up of the testicles, accom- panied with numbness along the inside of the thigh, sometimes running down even to the foot. He also often feels a tormenting violent pain in the sole of the foot, sometimes a slight sensation of numbness, or a trouble- some tickling. As the irritation of the stone on the walls of the bladder continues, they are brought into a state of slow inflammation, the urine is mingled with much thick mucus; the walls of the bladder become thick- ened, and contract around the stone, so that with diminished capacity, and inability of distention, the bladder can no longer retain the urine within it, but discharges it every minute. The inflammation may extend to the ureters and kidneys, and it may eause ulceration and other kinds of destruction. In consequence of these symptoms, and of the constant pain which deprives the patient of rest and sleep, the digestive organs are sympathetically affected, the powers sink, and are at last destroyed with symptoms of hectic fever. 2022. These symptoms undergo various modifications according to the constitution of the patient, the nature of the stone, and the place where it is situated. The more sensitive the patient is, the less regular and quiet his mode of living, the greater are his sufferings. The larger the stone is, the more severe are the symptoms. With smooth stones, or with such as are enveloped in a sac, the symptoms are less; but with a stone lying loose, of an angular shape, or of the mulberry kind, they are more violent. If the stone be seated at the orifice of the ureter or in the neck of the bladder, the symptoms are more severe, and in the latter case it may hinder or prevent the discharge of urine ; it may, by irritating the openings of the spermatic ducts, produce painful priapism and swelling of the testicles. A- stone frequently causes no inconvenience if it be fixed at any one part of the bladder, and the pain only comes on when, by any movement or exertion, it is brought into another place. If a large stone be constantly at the bottom of the bladder, it may cause ulceration of it, and also of the corresponding wall of the rectum, and in this way be discharged. The same also may happen in women by ulceration of the wall of the vagina. Instances have, however, occurred in which even large stones lying loose in the bladder have been borne for many years without having produced any particular inconvenience. • Each several kind of stone has its own peculiar symptoms (Prout.) With uric acid stones they are generally less severe than with other kinds ; the urine is natural, but a little darker in colour; its specific gravity is greater than usual; on cooling, it leaves a crystalline sediment mixed with mucus, which increases on any accidental irritation; the urine, at first turbid, becomes clear by standing. With oxalate of Ihne stones the symptoms are very violent, (I have, however, several times noticed SYMPTOMS. 277 the reverse,) and the urine is clear, and deposits neither uric acid nor phosphates. Stones composed of phosphates produce the most severe symptoms; the urine in this case is quite characteristically curdy, turbid, specifically light, deposits much phosphate and mucus, sometimes is alkaline, putrid, stinking, and secreted in large quantity, and the constitution generally suffers considerably. 2023. The above-mentioned symptoms lead to the supposition merely of the presence of a stone in the bladder; a certain knowledge of it can only be obtained by examination with a sound, by the distinct feel of a hard resistance, and by the metallic tinkling. Examination {searching, as it wTas formerly, and sounding, as it is now generally called) even, can in many cases give only a doubtful result, or none at all; for instance, with a very small stone, such as are for the most part or completely covered by the inner membrane of the bladder, or by a false membrane, or are enclosed in a diverticulum of the bladder. As it depends on the size, nature, and position of the stone, whether it be touched by the beak of the sound more readily or with difficulty, so, in making the examination, the bladder must be gently felt all round, and the patient sounded with his bladder full and empty, and in different postures. Ex- amination by introducing the finger into the rectum at the same time, may make easy the finding of the stone; and a large stone which lies in the bottom of the bladder may often be distinctly felt by the finger in this way. Klein (a) observes that silver sounds, in very sensitive persons, often excite con- siderable pain, and contraction of the bladder, which interferes with the examination of the stone; whilst the iron sound, or even an elastic catheter, causes neither pain nor contraction, and easily finds the stone. [(1) Brodie says :—" In some cases a calculus which has not been discovered by means of the sound is at once detected by means of the elastic gum catheter. This is an observation made by Sir Everard Home, the correctness of which I have had frequent opportunity of verifying. The gum catheter should be introduced without the iron stilette, while the patient is standing, with his bladder full of urine. You allow the urine to flow through the catheter, and, as the last portion of it comes away, the calculus falls down on the extremity of the instrument, in withdrawing which you feel it quite distinctly." (p. 277.) It may be well to observe, that if the patient's symptoms continue it will be right to sound him again and again at proper intervals, as the stone may increase in size or alter its position, so that at last, after repeated fruitless attempts during many months, it may be detected. This I have known in more than one or two instances. In rare cases, however, though a stone really exists, it cannot be found by the most careful sound, which happened to the celebrated French surgeon, La Peyronie, in whom the stone was only discovered after death. " There may be a stone," Brodie observes, " without the usual symptoms, and there may be many of the usual symptoms without a stone in the bladder. In children especially, the disposition of lithic (uric) acid sand by the urine will not unfrequently produce not only pain in the glans, but bloody urine, and all the other symptoms of stone in the bladder." And he mentions the case of a boy who suf- fered severely, but no stone could be found after repeated soundings "I then inquired more particularly," says he, " into the child's health in other respects, and the result was, that I was led to prescribe an occasional dose of calomel and rhubarb, with rhubarb and sal polychrestin the intervals; and under this simple plan of treat- ment all the symptoms disappeared in the course of a few weeks." (p. 275.) I have known a similar case as regards the symptoms in a child, of two and a half years, who suffered very severely; a stone was believed to have been felt, and he was cut, but no stone was found. No violence was used, nor the bladder irritated by continued use of the instruments ; but it being soon discovered that there was no (a) Praktische Ansichten der bedeutendsten Chirurgischen Operationen, part iii. p. 35 Stuttgardt., 1819. 24* 278 STONE IN THE BLADDER ; stone, he was put to bed, quickly recovered of the operation, and at the same time lost all symptoms of stone. A polypus in the bladder may sometimes, from its irritation, produce symptoms of stone, and, being struck by the sound, may lead to the operation. There is a case of this kind in the Museum at St. Thomas's; the patient recovered from the operation, but died some time after, when the nature of the disease was ascertained. ■—J. F. S.] ' 2024. By sounding, information can, to a certain degree, be obtained of the size and other conditions of the stone. If the stone be large, it is always felt at the point of the sound, whatever direction be given to it; if small, it frequently slips away, and is only felt at intervals; if it be bossed, the sound is often caught. Hard stones give a clear, and soft ones a dull sound ; but in reference to this point the feel is often very deceitful. When a stone does not lie loose in the bladder, but is lodged in a sac, the sound, as it does not touch it directly, gives a feel which cannot decidedly distinguish between a stone and a fungous growth of other swelling on the inner surface of the bladder. Leroy d'Etoille (a) has invented an instrument for measuring urinary stones; it is easy, however, with the greatest care, to be deceived by it, as it is difficult to avoid grasping the stone again and again in the same diameter. The best lithometer is, according to the observations of Sanson and Pigne, the common sound. When the stone is found, the beak of the instrument is to be carried to the hind end of the stone, and then brought gently forwards, moving it at the same time gently on its axis. At each motion the stone is felt, and if it be noticed how far the sound pro- jects from the urethra, at the moment it touches the hind end of the stone, and how much further it projects at the time when the stone can no longer be felt, then the diameter of the stone from behind forwards may be determined. For the purpose of ascertaining the lateral diameter, the sound must be carried from one side to the other, and the extent noted through which its handle passes, by which means the lateral diameter ean be measured. In order to hear distinctly the-stroke of the sound upon the stone, and to guard against mistake, if the stone be covered with mucus, or if a hard part of the wall of the bladder be touched, it has been proposed to apply the ear to the pubic region. Moreau and Berier have added a stethoscope to the sound. Pfriem (b) also, and Leroy d'Etiolle use a long elastic tube, the upper end of whieh is furnished with a stethoscope. [It is often difficult to ascertain the size of a stone, as its position may render it more or less accessible to the sound, and when its diameters are unequal the sound may travel upon it in such way as to give a notion of its size very contrary to that it really has. The readiness with which the stone is struck immediately on the entrance of the sound into the bladder, and the less or greater ease with which it can be displaced are probably among the best means of concluding satisfactorily as to its bulk; and more especially if the time during which the patient has had symp- toms of the disease be taken into the account; as if these have existed long, it may be expected the stone is large, whilst the contrary may be presumed if the symp- toms have been recent.—j. f. s.] 2025. The following are the various modes oftreatment recommended and employed for the removal of stone in the bladder :— First, The internal use of stone solvents (Lithontriptics.) Second, The injection of stone solvents into the bladder. Third, Solution by means of the galvanic pile. Fourth, Extraction of the stone through the urethra. Fifth, Breaking up the stone in the bladder (Lithotrity.) Sixth, The operation of cutting for the stone (Lithotomy.) (a) Journal general' de Medecine, vol. cix. p. 5. 1829. (6) Das Lithoscop oder Beschreibung eines instruraentes zur sicheren Diagnose der Harnblasen steine. Wurzburg, 1838. CONSTITUTIONAL SOLVENTS. 279 I.—Internal Use of Stone Solvents. (Remedia lithontriptica, Lat.; Steinauflbsenden MUtel, Germ.) 2026. The stone-solvents, which in former times were used in so great number, although without any knowledge of their possible operation, can only by the advance of chemistry^and by a precise knowledge of the constituents of stone in the bladder, attain their proper application and efficiency. The circumstances which have been considered in the treatment of gravel also apply here. {par. 2011-2013.) For stones con- sisting of uric acid, alkalies, for those of phosphates, the use of acids have been recommended, with corresponding dietetic treatment. In regard to acids, it must also be added, that they operate only against the phosphatic diathesis, and probably have no effect in dissolving stones, except by injection. Many empirical remedies consist principally of alkalies, as Stephens's remedy? and others. Some, as so many of the vegetable remedies, operate only by allevia- tion, through the large quantity of drink combined with their use. Many mineral waters operate both ways. 2027. The efficacy of these remedies has been too highly valued by many practitioners, and by others too much decried. If we cannot expect by the use of these remedies to dissolve large stones, yet, how- ever, their increase may be prevented, the symptoms caused by the stone diminished, and small stones perhaps got rid of. Under circumstances which forbid the removal of a large stone by operation, or after the per- formance of an operation to get rid of the diathesis producing stone, their employment is always very advantageous. Upon the effect of pure water see Littre (a); of Stephens's remedy, see Morand (6), Baume (c) ; of lime water, see White-. R. (d), Burlet (e), Sega- las (/), Lancier (g); of magnesia, see Brande (h), Hoffmann (i); of carbonate of soda, see Mascagni (j), Magendie (k), Leroy (I) ; of bicarbonate of soda, see Genois (m); of the mineral waters of Vichy see Charles Petit (n). Upon the operation of these different remedies, various experiments have been made, and especially the efficacy of the waters of Vichy proved by A. Chevalier (o). Even when, by the continued use of alkalies, the inconvenience of stone in the bladder are arrested ; there is, according to Howship (p),.no proof that it is dissolved; for, by the specific effect of the alkalies on the bladder, its coats are relaxed, and so a sac is formed by the weight of the stone. If, then, the disturbance of the diges- tion, which has followed the use of alkalies, render the employment of tonic (a) Mem. de l'Acad. des Sciences. 1720. (k) Above cited. p. 436. (I) Expose des divers procedes employes (b) Ibid., 1740. p. 177. jusqu'a ce jour pourguerir de la Pierre sans (c) Elns6ns de Pharmacie, p. 200. avoir recours a l'operation de Taille, p. 59. (d) An Essay on the virtues of Lime, in Paris, 1825. the Cure of the Stone. Edinburgh, 1755. (m) Revue Medicale, 1826. vol. iii. p. 515. (e) Recueil de l'Acad. des Sc. pour 1700. (n) Du Traitement medicale des Calculs (f) Essai sur la Gravelle, p. 59. Urinaires et particulierement de leur riisso- (g) M6m. de l'Acad. de Medecine, vol. i. lution par les eaux de Vichy. Paris, 1834. p. 405. Nouvelles Observations gnerisons dans les (h) Philosophical Transactions. 1810. p. calculs urinaires an moven des eaux ther- 186. males de Vichy. Paris,")837. (i) Observations et Annotationes, cent. i. (o) Essai sur la dissolution de la Gravelle cap. v. et des Calculs de la Vessie. Paris, 1837.— (j) Memorie della Societa Italiana, vol. See also Willis, above cited. xi. No. 34. (p) Above cited, p. 102. 280 STONE IN THE BLADDER; remedies necessary, whereby the muscular activity of the bladder is again excited, the bladder contracts completely around the stone, and encloses it in a blind pouch. Others have imagined, that by the alkalescence of the urine thus produced, a deposit of phosphates upon the stone takes place, by which the irritating effect upon the bladder is lessened. [The best instance of a stone having undergone partial solution whilst in the blad- der is Liston's case, C. f. 8, in the Museum of the Royal College of Surgeons. It was removed by operation. "The external surface of the calculus is very rough and uneven, and in some places is eaten i§to small holes, which are excavated, or, as it were, undermined at their sides. Its section shows that the concentric layers of uric acid, of which the calculus is composed, are not continued entirely round it, but terminate abruptly at those parts which correspond to the excavations on the surface, as if a portion of the calculus at these points had been either broken away or dis- solved. That these effects, however produced, must have taken place whilst the calculus was in the bladder, is shown by the layer of the earthy phosphates covering all its irregularities" (a).] II.—Injection of Solvents into the Bladder. 2028. Injections into the urinary bladder, which had long been recom- mended and employed for the solution of stone, were first subjected to definite rules by Fourcroy and Vauquelin (6). The solution of uric acid and urate of ammonia was to be effected by diluted alkalies; those composed of phosphates, by dilute hydrochloric acid; and those of oxa- late of lime, by dilute nitric acid. With the view of acting more power- fully upon the stone, without subjecting the bladder itself to the irritating and solvent materials, it has been endeavoured to enclose the stone in a bag which could withstand the effect of the injection; for which purpose Percy, Civiale, and Leroy (c) have made some proposals, and Robi- net {d) has recommended a peculiar apparatus, by which the stone may be enclosed in a bag made of intestine, and the injection made by means of a catheter with a double passage. Phosphatic stones of triple phosphate and lime, are said not to be dissolved by solutions of alkaline bicarbonates, but broken up and converted into powder. Oxa- late of lime stones are liable to the same change. (Willis.) A. Ure recommends the use of hippuric acid, (carbonate of lithia,) from which, however, according to Garrod's and Keller's experiments, but little advantage can be expected. Berze- lius, who has expressed himself favourably as to the possibility of the success of injections, and has recommended frequent trials, proposes a lukewarm mixture, of one part of carbonate of potash and nine hundred parts of water, with some muci- lage; and in cases where the stone consists of uric acid, a solution of borax. [Dorsey, On the Lithontriptic Virtues of the Gastric Liquor. Phila- delphia, 1802.—g. w. N.] 2029. With the purpose of effecting the solution of the stone by the continued flow of a lage quantity of water, of some chemical solvent, Gruithuisen (e) has proposed an apparatus, and Cloquet (/) has recommended again the double-passaged catheter previously proposed by Hales. 2030. Opinions as to these modes of treatment differ as much as those (a) Taylor's Catalogue, part i. p. 92. (d) Repert. gen. d'Anat. et Physiol pathol. (b) Memoires de la Soc. d'Emulat, vol. ii. et de Clin. Chir., vol. i. Paris, 1826. p. 76. (e) Salb. Med.-Chir. Zeit, vol. i. p. 289. (c) Aboved cited, p. 88. 1813—Textor; in same, vol. ii. p. 94. (/) In Leroy, above cited, pi. ii. f. 7. INJECTED SOLVENTS. 281 upon internal treatment. There are still but few facts which prove the efficacy of this plan of proceeding. The frequent variety in the layers of the stone must not indeed be considered as a very great obstacle to this treatment, as partly by the nature of the urine, by the result of the injections, by the modes of treatment, to be mentioned when crushing the stone is treated of, by the extraction of single fragments of stone, its character at different periods can be ascertained. Stones of oxalate of lime would be dissolved with most difficulty (a). The most recent experiments made on this subject are those of Pelouze (6), from which it appears—First, that the effect of different agents upon urinary stones is less upon the substances of which they consist, than upon the animal matter. The ope- ration proceeds very slowly, even out of the bladder. Second, that by drinks and baths a cure is scarcely ever effected. Third, that the result of injections, although they act more powerfully, is problematical, and the danger of inflammation is not counterbalanced, as in lithotrity, by a quick destruction of the stone. Fourth, that although the combination of lithotrity with injections increases the probability of success, yet it is most advisable to proceed with lithotrity (c). Prout observes :—"When the very weak state of the solvent that can be injected into the bladder is taken into account, the consequent length of time necessary for continuing the experiment, and above all the refractory nature of certain calculi, I confess I am very much disposed to doubt if any solvent at present known can, in the great majority of instances, be ever so administered as to produce the desired effect; and this, I believe, is the general opinion on the subject." (p. 284.)] " It has been observed by chemists," says Brodie, " that lithic acid admits of being dissolved by a strong solution of pure or caustic alkali. It has been also, observed that calculi composed of the phosphates are acted on by the mineral acids, and it may not unreasonably be entertained as a question, how far those changes, which take place out of the body, may be produced while the calculus is still in the bladder of a living person. * * * I fear those who have expected by these methods to relieve patients of lithic acid calculi, have much overrated the effects of alkaline lixivia on them. The fact is, that although alkalies certainly are capable of acting on this kind of calculus, their action, except when employed in a very concentrated form, is so inconsiderable, as to amount almost to nothing. Neither the stomach nor the bladder is capable of bearing the quantity of alkali which is necessary to the production of the desired effect; and even if they were, it would be impossible to maintain so constant a supply of the alkali as would be necessary to the destruction of a calculus of even moderate dimensions. Mr. Brande, moreover, has observed, that the carbonate of potass and soda have no action on lithic acid; that they are incapable of dissolving it; and that if the pure alkali be taken by the mouth, it never reaches the bladder in this state, but only in that of a carbonate; and here then is an insuperable objection to all attempts to dissolve lithic (uric) acid calculi by means of alkalies taken into the stomach. When there is a lithic (uric) acid calculus in the bladder, and the lithic acid diathesis prevails in the system, the first effect of alkalies taken into the stomach is to render the urine neutral; thus preventing the further increase of the calculus. So far, then, alkalies are useful. But if they are administered in still larger quantity, so as to render the urine alkaline, the phosphates begin to be deposited. The calculus then continues to grow even more rapidly than before; but its composition is altered, and layers of the triple phosphate are deposited on the lithic acid nucleus. Such is the view of the subject taken by Mr. Brande." (p. 290-92.) Brodie shows the fallacy of the statements in reference to the presumed solution of stone, by observing that the fragments occasionally passing, are to be referred to fracture of the stone from mechanical causes, as already mentioned ; or that the sup- posed fragments are in reality new formations, and the result of the medicines em- (a) In the British and Foreign Quarterly (6) Comptes-rendus de l'Acad. des Sci- Medical Review, vol. xii. p. 398; and also in ences, vol. xiv. p. 429. 1842. Jones, p. 118, all has been collected in (c) Willis and Jones, above cited. reference to the effects of Injections upon Stones. 282 SOLUTION BY GALVANISM. ployed. As to the cessation of the symptoms, it is no proof the solution of the stone, as by the use of medicine, a fresh coating may be given to it of a less irritating character, and the stone still exist, as in the case of Admiral Douglas mentioned by Astley Cooper (a). Brodie, however, considers that " the mineral acids undoubtedly exercise a greater chemical action on calculi composed of the phosphates than alkalies do on those which are composed of lithic (uric) acid. * * * I found that where the mucous membrane of the bladder was not inflamed at all, or inflamed only in a slight degree, the proportion of nitrip acid might be increased to two minims or two minims and a half of the concentrated acid to an ounce of distilled water, without any ill conse- quence or even inconvenience arising from it. I next endeavoured to ascertain to what extent a solution of this strength was capable of acting on a calculus of the mixed phosphates. The change produced was sufficiently obvious, especially when the solution was made to pass over the calculus in a stream for a considerable time. It gradually diminished in size, and at last began to be broken down into minute fragments." For this purpose he at first used a gold catheter with a double chan- nel, through which a constant current was kept up; but afterwards found an elastic gum bottle with a stop-cock, and elastic gum tube attached to it. He first washed out the bladder with distilled water to get rid of the mucus lodged in it, and then injected the solution of nitric acid very slowly, using the same liquid over and over again several times. The liquid was afterwards tested with a highly concentrated solution of pure ammonia, and it was found that if the ammonia was added in suffi- cient, but not too large quantity, the phosphates were precipitated in abundance. Hence he concludes, '■'■first, that a calculus, composed externally of the phosphates, may be acted on by this injection, so as to become gradually reduced in size, while it is still in the bladder of a living person; second, that there is reason to believe that small calculi, composed throughout of the mixed phosphates, such as one met with in some cases of diseased prostate gland and bladder, are capable of being entirely dissolved under this mode of treatment, and that it is probable that it may therefore be applied with advantage to some of these cases, in which, from the contracted state of the bladder, or from other circumstances, the extraction of such calculi by means of the urethra-forceps, cannot be accomplished," (p. 292-99.)] III.—Of Dissolving Stone by means of the Galvanic Pile. 2031. Gruithuisen (b) rests his proposal of dissolving urinary stone by the action of the galvanic pile, upon Desmortier's experiments. Prevost and Dumas (c) haye made experiments both out of the body and upon animals. The apparatus consists of an elastic catheter, con- taining two platina conductors, covered with silk throughout their whole length, except at their ends, which are kept apart by a spring, and attached to an ivory knob, wdiich closes the opening of the catheter. This knob is composed of two hemispheres, each of which is attached to a conductor, so that the flat surfaces where the platina is exposed, comes in contact with the stone. An injection of diluted nitric acid renders the galvanic pile more active than water alone. With this treatment, no experiments have yet been made on men. [In 1844 an American named Hull, in London, attempted to dissolve stone in the bladder by galvanism, but I do not know with what success. The patient had stone, for I sounded and felt it.-—j. f. s.] (a) Lectures on Surgery, vol. ii. p. 241. xxiii. p. 202. 1823.—Leroy, Alteration of lb) Above cited. the Apparatus, in his work above cited, p. (c) Annales de Chimie et de Physique, vol. 102. EXTRACTION BY URETHRA. 283 IV.—Of the Extraction of the Stone through the Urethra. 2032. The shortness and extensibility of the urethra in females, and the not unfrequent spontaneous passage of stones of considerable size, have led to the extraction of stones in women, by dilating the urethra. Circumstances are less favourable in men, and the instances of voidance of large stones by them are much rarer. According to Prosper Alpi- nus (a), the dilatation was specially suited to men, and was performed among the Egyptians by blowing air into the urethra through tubes of increasing size, after which the stone was pressed into the neck of the bladder by the finger introduced into the rectum, (in women the finger was placed in the vagina,) and then the stone was brought out by sucking vigorously at the penis. Enlargement of the diameter of the urethra to five lines can be effected in men only with much trouble; in most cases such extension is unbearable. Small stones, therefore, can alone be extracted in this way from men, and the enlargement of the urethra is best effected by increasingly thick elastic sounds. When the urethra has been sufficiently enlarged, the patient must hold his water, bend himself forwards, and as the sound is withdrawn quickly, the small stone escapes with the stream of urine, or is extracted by a peculiar pair of forceps (1). For enlarging the female urethra, Weiss's dilator is used (2). Forceps of this kind had been formerly proposed by Sanctorius and Severinus, and Hunter's forceps had been employed for the same purpose (b). Astley Cooper's forceps (c) are especially applicable. According to him such little stones are always lodged in a sac of the bladder behind the enlarged prostate gland, and are frequently not discovered, if in sounding, the point of the instrument be not directed towards the rectum, or the front of the rectum pushed up by the finger intro- duced into it (3). [(1) Brodie, for this purpose, directs the introduction of "a bougie, or a metallic sound, of such a size as the urethra will admit without inflammation being induced. Every day, or every other day, according to circumstances, introduce one a little larger, and thus you may dilate the urethra gradually, until it is a good deal larger than its natural size. * * * When this process has been carried as far as it can be, let the patient drink plentifully of diluting drinks. It may be worth while even to give some of the compound spirit of juniper or other diuretic, at the same time, and the calculus will probably, some time or other, be carried by the current of urine into the dilated urethra;" or, "once daily introduce a large bougie into the urethra and bladder, and there let it remain; then let the patient drink plentifully of barley water, or toast and water, or weak tea, so that the bladder may become loaded with urine. When the patient can bear the distention of it no longer, let him place a vessel on a chair, standing, and leaning forward over it; on the bougie being with- drawn, the urine will follow in a full stream, and the calculus may probably accom- pany it." (pp. 281, 82.) (2) In the female the urethra being short will easily dilate of itself, and even permit the passage of a stone weighing an ounce, as in a case mentioned by Astley Cooper ; and, " unless a stone be extremely large," he says, " it should be removed by dilatation of the urethra, which may, by a speculum or pair of forceps, be opened sufficiently in a few minutes for this purpose. The advantage attending this* mode of extracting a stone is, that the passage again contracts, and the urine is afterwards (a) De Medicina iEgypt., p. 224. Lugd. (c) Mrdico-Chirurg. Trans., vol. xi. p. 359, Batav., 1719. pi. vi. 1820. (6) Leroy, above cited. 284 STONE IN THE BLADDER ; retained. In the first case in which I performed this operation in Guy's Hospital, having used sponge tent, the patient perfectly recovered in a very few days." (pp. 301, 302.) This is not, however, always the case, for sometimes the urethra is long before it recovers its tone, and consequently during that period there is a tiresome incontinence of urine.—j. f. s.] Liston (a) says:—"The best mode of extracting foreign bodies from the female bladder is to widen the urethra gradually by means of the screw dilator, then, by the induction of a straight blunt-pointed knife, to notch the neck of the bladder slightly towards each ramus of the pubes, so as to divide the dense fibrous band encircling it; the dilatation is continued, and in a few minutes the finger can be admitted, the stone then can be readily grasped by a pair of forceps; and it is astonishing how large a body may be removed by these means." (p. 525.) (3) The urethra forceps, commonly called Cooper's, were the invention of Weiss, the instrument-maker, which Brodie considers objectionable, as "it is difficult to explore with it every part of the bladder, and in opening the blades the neck of the bladder is always painfully dilated ;•" and he prefers another instrument afterwards invented by the same maker, and "composed of two pieces of steel, one sliding longitudinally in a groove of the other. The extremity which enters the bladder is curved, but not in the manner of the common catheter, the curve being more abrupt and the curved part considerably shorter. When the forceps is to be opened the sliding piece is drawn towards the handle, and thus the blades, in being separated, are still kept parallel to each other; they are closed by an opposite movement. * * * The patient should be laid on his back, and it is generally better that his pelvis should be supported by a thick cushion, so that it may be higher than his shoulders. The first step of the operation is to introduce a silver catheter, and thus empty its contents. From five to six ounces of tepid water are then to be injected into the bladder, so as to distend it moderately. If any considerable portion of the water should escape, the injection should be repeated, it being absolutely necessary that the operation should never be attempted on an empty bladder. The forceps is next introduced, and, of course, with the blades closed. It is first to be used as a sound, so as to ascertain the exact situation of the calculus. If this be not readily detected, the patient may be directed to turn on one side, placing himself on his back again afterwards, by which change of position the calculus may probably be made to roll into some more convenient place within reach of the forceps. The blades of the forceps are then to be cautiously opened over the calculus, and afterwards closed upon it. By this simple management, with a light hand, the calculus is seized with facility in many cases, otherwise you may adopt the following method, which rarely fails:—Let the forceps be opened with the convexity of its blades pressed against that part of the bladder which is towards the rectum, so as to make it the lowest or most depending situation. Then, by a slight motion given to the handle of the instrument, the cal- culus is made to roll into its grasp, and thus 1 have often been enabled to remove several small stones at once. * * * When the calculus is grasped you may know exactly its diameter by means of a scale fixed to the handle of the forceps." If small, Brodie says, forceps and stone may be withdrawn at once; if very large, so that it will not enter the urethra, it may be dropped at once, and other means resorted to; but if of intermediate size, and capable of entering the urethra, from the easy dilatability of the neck of the bladder, so as to be "drawn into that portion of the canal which lies in the perinaeum, and there stops, it may then be very distinctly felt through the integuments behind the scrotum; and if a small incision be made on it in this situation, it is easily extracted, the forceps, after the removal of the stone, being closed and withdrawn in the usual manner." An elastic catheter must be left in to draw off the water and prevent dribbling through the wound. If the forceps and stone can be brought forward and only "meet an impediment in the anterior part of the canal, that is, at the external orifice or exactly at the anterior part of the scrotum, or somewhere in the intermediate space; if the impediment be close to the orifice that part is easily dilated by means of a probe-pointed bistoury; and if it be in another part of the canal, you may remove it by means of an incision made through the skin, corpus spongiosum, and membrane of the urethra. Let me caution you, however, never to make such an incision into the urethra immediately in front of (a) Practical Surgery. CRUSHING, OR LITHOTRITY. 285 the scrotum. It is difficult when you do so, even by the constant retention of an elastic gum catheter, to prevent a small quantity of urine finding its way into the loose cellular texture of the scrotum, and this may be productive of a succession of troublesome abscesses, or even of dangerous consequences." (p. 283-87.)] V.—Of Crushing the Stone. (Lithotritia, Lithotripsia, Lat.; Zertriimmerung des Steines, Germ.; Lithotritie, Lithotripsie, Fr.) Leroy d'Etiolle, Expose des diverses precedes pour guerir de la Pierre sans l'Operation de la Taille. Paris, 1825. Civiale, Destruction des Calculs sans avoir recours a la Taille. Paris, 1823. ----, De la Lithotritie, ou Broiement de la Pierre dans la Vessie. Paris, 1826. 8vo. Bancal, Manuel pratique de la Lithotritie. Paris, 1829. Tanchon, Nouvelle Methode pour detruire la Pierre dans la Vessie sans operation sanglante. Paris, 1830. Heurteloup, Lettre a l'Acad. des Sciences. Examen critique de l'Ouvrage de M. le Dr. Civiale, intitule, de la Lithotritie, Broiement de la Pierre dans la Vessie, &c. Paris 1827. 8vo. ----, Principles of Lithotrity, or a Treatise on the Art of extracting the Stone without incision. London, 1831. 8vo. ----, Cases of Lithotrity. London, 1831. 8vo. Leroy d'Etiolle, De la Lithotripsie. Paris, 1836. Civiale, Parallele des divers Moyens de traiter les Calculeux. Paris, 1836. ----, Traite de l'Affection Calculeuse. Paris, 1838. Schleiss von Lowenfeld, Die Lithotripsie in Bezug auf Geschichte, Theorie und Praxis derselben unter Benutzung der neuesten Erfahrungen der Franzosischen Aerzte hieriiber. Miinchen, 1839 ; with eight plates. Ivanchich, V., Kritische Beleuchtung der Blasenstein-Zertrummerung, wie sie heute dasteht. Wien, 1842. 2033. Although hints about the extraction of an urinary stone after previously crushing it in the bladder, are found in Celsus (1) and Al- bucasis (2), and the successful experiments of two persons upon them- selves have been recorded (3), yet Gruithuisen {a) made the first actual proposal, in which, by means of a straight tube introduced into the bladder, and a wire loop projected out of it, the stone being held fast, was penetrated by a borer or trepan passed through the tube, and the crushing of the small pieces effected by the introduction of forceps through the tube; this was not thought any thing of, and partly because the proposed method was considered impracticable. Even Elderton's (b) instrument, curved like the common catheter, and with two opening arms, by which the stone might be grasped and destroyed by means of a file, was not much regarded. (1) Celsus (c) says:—"Calculus fendendus est. Id hoc modo fit. Uncus inji- citur calculo, ut facile eum concussum teneat, ne is retro revolvatur: turn ferramentum adhibitur crassitudinis modicae, prima parte tenui, sed retusa, quodadmodum calcu- lum ex altera parte ictum fendit." (2) Albucasis (d):—" Let a slender instrument be taken * * * and gently intro- duced into the penis; roll the stone into the middle of the bladder, and if it be soft, let it be broken and discharged." According to Haller (e), Sanctorius described a three-armed catheter, through (a) Salzburg Med.-Chir. Zeitung, vol. i. p. (c) De Medicina, book vii. chap. iii. sect. iii. 289, f. 1-9. 1813. (d) Liber Theories necnon Practical Vol. (b) Edinb. Med. and Surg. Journ., vol. xv. Aug. Vind., 1519, p. 94. p. 261, f. 1, 2, 3. 1819. (e) Biblioth. Chirurg., vol. i. p. 313. Vol. hi.—25 286 STOXE IX THE BLADDER ; which a stilette with a file end was passed, and the stone broken up, and the pieces having been seized by the branches of the catheter, were removed. (3) The former of these persons introduced, by means of a flexible sound passed into the bladder a straight steel rod with its extremity ground to a point, down to the stone, and struck upon the outer end of the rod, in consequence of which little pieces were separated from the stone and voided with the urine (4). The latter, by means of an elastic sound, carried down a fine file, about thrice in every twenty-four hours, between the stone and the bladder, and used it as a file upon the stone, which he endeavoured to bring near the neck of the bladder (5). (4) This (a) the celebrated case ("if well proved," as Chaussier and Percy observe) of the Monk of Citeaux, and to the notice above given may be added, that having introduced the rod, he struck its end with a hammer with some little sharp sudden strokes, sufficient to detach some little pieces and splinters, which were car- ried off by the urine, and with which in the course of a year he filled a little box. (5) This person was General Martin (b), who gives the following account of his proceedings :—" As I generally found the stones by the neck of the bladder, it sug- gested to me that by making a catheter with small holes on the side, I perhaps could break the sharp points of the stones by passing the catheter between the stones and bladder; this by a small catheter I could introduce between the stones and bladder, and I succeeded in bringing many small pieces away, and after no more. But as I constantly found the stones, my good genius suggested me to make files, and by introducing them on the catheter, and with small motion, I either filed or scraped the whole stones out during about nine months. When I could not get at the stones, I injected warm water in the bladder, which I rejetted or urined out with force, and large stream, and mostly always the stone came to the neck of the bladder and stopped the water, then it was my time to file again, which I did, inclining my body against the wall for to be able to keep the stones as much as I could in position to be able to fill it often. * * * As I saw my progress by many small pieces which I still have, besides the sand, or fine sandy part, it made me persevere in that mode till I brought every piece out, and then, afterwards, I found myself able to walk, ride, &c, as every body else, which I had not done for many years; and I made water very well, though still always a little matter preceded the urine, and also by straining, some few drops came out after the urine." (pp. 251, 252.) How long time was occupied in this process is not mentioned, nor does it-appear how long he lived after having, as he stated, thus relieved himself. He died in 1800, and in the note appended to the letter, Everard Home says:—" There can be no doubt, but the diseased state of the prostate gland was the cause of his death, since the pain of the urine passing over its surface was greater than he could well.bear. From his own confession of having a fit of the gravel, after he had brought the stones away, and being obliged to tickle the head of the penis before he could make a drop of water, I am strongly disposed to believe, that had the body been inspected, more than one stone would have been found in the bladder." (p. 259.)] 2034. The path first cleared by Gruithuisen has been retrodden by Civiale, Leroy D'Etiolle and Amussat, and the instruments they have advised, which correspond with those proposed by Gruithuisen, are to a certain extent to be considered merely modifications of his. For this reason the contention between Civiale and Leroy D'Etiolle is of less consequence, as even the straightness of the instrument, the result of Amussat's observations, had been already proposed by Gruithuisen. In other respects, however, the merits of these surgeon's are not diminished, as by their emulation this operation has been perfected and subjected to definitive rules ; and as also it was first performed by Civiale on living persons, and not merely brought into practice but its permanence ensured. Besides Civiale, Leroy D'Etiolle and Amussat have most contributed to the improvement of the instruments, Jacobson, (a) Rapport fait a l'Academie Royale des (b) Home, Practical Observations on the Sciences, par Chaussier et Percy, sur le Treatment of Diseases of the Prostate Gland, nouveau moyen du Dr. Civiale, p. 171. vol. ii, 1818, Paris, 1824. CRUSHING, OR LITHOTRITY. 257 Heurteloup and Charriere's inventions especially, to the simplifica- tion and greater certainty of the practice, so that of late years this opera- tion has been brought to a great degree of simplicity and perfection. 2035. The numerous instruments recommended for the practice of lithotrity have this in common, that having been introduced through the urethra into the bladder, they grasp and fix the stone, and by a force exerted upon it, break the stone into so small pieces, that they can pass through the urethra. All these instruments may be most conveniently arranged under three classes:—First, the stone being grasped by its periphery, is gradually destroyed towards its centre; second, it is per- foratedy to render it breakable, so that it may then be crushed ; third, it is then crushed by pressure from its periphery, towards the centre. To theirs/ class of these instruments, which effect the gradual destruction of the surface of the stone, belong the instruments of Elderton (1819,) of Meyrieu, made public by Tanchou, (1830,) of Recamier, (1830,) which fix the stone with forceps, and act upon it with the file ; Rigal's (1830) instrument, which fixes the stone with a perforator, for the purpose of moving it upon the file-like surfaces of the arms of the forceps (foret a chemise.) To the second class belong the instruments of Gruithuisen, (1812,) of Civiale and Leroy D'Etiolle, (1823,) with the modifications of Griffiths, Luckens, Scheinlein; of Heurteloup, (1828,) and of Rigal, (1830,) for the purpose of breaking the stone by an eccentric power; of Pravaz, (1830.) curved like a com- mon catheter, and similar to that of Benvenuti (1830.) The form of perforator as given by Civiale, Leroy, Amussat, Greiling, Charriere, and others, varies very much. In the third class are Amussat's instrument, (1832,) Heurteloup's brise-coque, (1828,) Jacobson's instrument, (1830,) with its modification by Dupuytren, who increased the number of limbs for the purpose of getting rid of the angles, which the grasp forms; Leroy and Greiling's instruments; the percuteur of Heurte- loup, (1832,) with the alterations of Segalas, Bancal, Amussat, Weiss, Civiale, Leroy, Benique, Charriere, and others; Charriere's percuteur a pignon. Schleiss has attached a perforator to the percuteur so as to act in two ways upon the stone. The description of these instruments, which would be insufficient, is omitted, and the reader is referred for their complete description and engravings of them to the works of Leroy D'Etiolle, and others, and especially to those of Schleiss, von Lowenfeld, and others (a). 2036. The history of lithotrity affords a sufficient opportunity for deciding on the fitness of these various instruments. Those which effect a gradual rubbing away of the surface of the stone have never enjoyed any particular favour. The perforating instruments, although they led to the direct introduction of lithotrity, have been set aside by Jacobson's lithoclast; and both have been, to a certain degree, supplanted by Heurteloup's percuteur. From a close examination of the three-limbed perforating forceps of Civiale, and Leroy, of Jacobson's instrument, of Heurteloup's percuteur, with screw and hammer, or a pignon, there seem to be good grounds for their employment and effect. 2037. The tha\>.-limbed perforating forceps are indeed generally intro- duced with ease ; but there are circumstances in reference to the state of the prostate, which may render their introduction difficult, and even impossible. In general they readily grasp a large stone; but the en- trance of a large stone between their branches may be difficult, and it may also be exceedingly troublesome to grasp a small stone; their expanded branches may also injure a corresponding number of points on (a) Above cited. 288 STONE IN THE BLADDER ; the walls of the bladder. When the stone is grasped it cannot easily escape, its rubbing into fine powder is very favourable for its discharge; but at its final breaking up, there still remain fragments, the grasping and crushing of which is very difficult. Hence arises the tediousness of this method; the stone must be grasped, bored and let go, must be again grasped and bored, till it can at last be broken up. These manoeuvres are difficult, tedious and painful, to both patient and operator. One limb of the forceps may get into one of the bored holes, from which it is freed with difficulty ; the perforator itself, if it operate on an irregularly shaped stone, and which is perforated at one part, may act upon one arm of the forceps, and injure, or even break it. 2038. Jacobson's instrument is easily introduced; searching for and grasping the stone with it is less dangerous, as when it is opened, the stone almost of itself gets into it; on account of its curve, however, it is difficult to sound certain parts of the bladder—for instance, near its neck. Flat stones are always seized with more difficulty by it than by the three- limbed forceps, and not always easily fixed. The stone is sometimes broken slowly, without pain, and without the pieces striking injuriously against the walls of the bladder. No stone can resist its action (Dupuy- tren Pigne) ; and if the instrument should break, its pieces remain con- nected with the body of the instrument, and by giving it the proper direction, may be withdrawn with it, without danger or difficulty. The dimensions of the instrument, however, may be so large that it cannot grasp a large stone; it is, therefore, suitable only for small stones. It is, above all, necessary that the stone should be caught in the middle, as otherwise it is difficult to fix, and easily escapes. Lastly, the re- mainder of the stone may continue attached to the branches of the instrument, and render its withdrawal difficult, or even impossible; this awkward circumstance is, however, prevented by Leroy's modification. 2039. Heurteloup's percuteur is most easily of all introduced into, and managed when in, the bladder. Stones of every shape and size can be firmly grasped by it, and their escape is less to be feared than from any other instrument. The position of the stone when seized, can be more easily changed, its size measured, and every part of the bladder more readily examined, by the angular curve of the instrument. Its operation is powerful and quick; large stones can be crushed with it more quickly and with less effort, and are converted into a coarse soft powder; but the fragments of hard stones are very angular and sharp- edged, and produce, by irritating the bladder, pain, difficulty in their passage through the urethra, and frequently their lodgement there. The strength of the instrument, notwithstanding its small size, in comparison with others, is, when properly used, so great that there is no fear of its breaking. To this may be added, that it is by far the least costly instru- ment. The percuteur, therefore, possesses all the advantages of the other instruments, without any of their disadvantages, and it may be with certainty presumed that it will supersede them all. 2040. Before proceeding to the operation, the most perfect informa- tion must be obtained, by examination of the position, form, size, and consistence of the stone and of the state of the urinary organs. For this CRUSHING, OR LITHOTRITY. 289 purpose a common catheter may be made use of as already directed {a). If there be no circumstances contra-indicating lithotrity, if no further preparation of the patient be requisite, or it have been already made, the rectum must be emptied with a clyster some hours previous to the operation. Previous to the introduction of the straight perforator, Civiale and others have for the space of a fortnight, in addition to very strict diet and lukewarm bathing, enlarged the canal of the urethra, by the daily use of elastic bougies, to such extent as to render the introduction of the instrument easy. The patient is thus at the same time accustomed to the irritation of a foreign body, on which account Civiale also uses bougies, even when the passage of the urethra is sufficiently wide. 2041. The patient should lie upon a common bed, or upon a table covered with a mattress, both of which should be sufficiently high, that the operator have not to stop. It should also be narrow, and the mattress firm. The buttocks are to be raised on pillows, the back fiat, the shoulders and head a little raised. The patient should either lie length- ways and" the operator standing on his right side, or obliquely, with his rump on the edge of the bed, in which position his feet are either to rest on a stool, or to be supported by assistants, and the operator stands between his thighs. The beds specially for this purpose, as recommended by Heurteloup, Bancal, and Tanchou, are thus rendered superfluous, although they are advantageous, by placing the patient easily and quickly in the fitting posture, and giving the operator more facility and security. Rigal's chest-like contrivance, which contains all the lithotriptic instruments, may also be placed on a table to give the patient a proper position. The apparatus used for firmly fixing the instrument to the bed, when the stone is crushed with the hammer, is not necessary; for, even if the hammer be used, the instrument can be fixed by the hand alone, or by a moveable holder, as the crushing of the stone must only be attempted by light short strokes, and an im- moveable fixing of the instrument may, if the patient move, cause mischief. 2042. After voidance of the urine, a quantity of lukewarm water, cor- responding to the capacity of the bladder, is to be injected through a silver catheter, till a visible or sensible enlargement of the region of the bladder is produced, or the patient has an urging to make water. The aperture of the catheter is then stopped with the thumb, and the existence and position of the stone once more examined ; after which the catheter having been withdrawn, the lithotriptor is introduced. If the orifice of the urethra be very narrow, it must be enlarged downwards with Civiale's bistoury, or with a narrow button-ended bistoury, to the extent of a line or two. 2043. In using the three-limbed perforating forceps of Civiale and Leroy, the instrument, closed and properly oiled, must be held with the fingers, of the right hand, and the penis with those of the left, so directed that it occupies a middle position between erection and relaxation ; con- sequently almost at a right angle with the body, but forming towards the belly a somewhat obtuse angle. The same direction being given to the instrument, it is introduced into the urethra, and with gentle twirling and pushing alternately, carried on till it come to the under part of the pubic arch, without changing its direction, or that of the penis. The instru- ment and the penis are now gradually sunk down, at first parallel to the horizon, and then brought so far below it as can be done without any (a) Catheters specially for examination, and of similar construction to that of Heurte- loup's percuteur, are given by Schleiss. 25* 290 STONE IN THE BLADDER J great difficulty, and then its point gently pushed forwards. If this can- not be done, the instrument must be again raised and sunk till the point get under the pubic arch; the instrument is then carried in the same direction through the prostatic part into the bladder, which is indicated by a peculiar feel, by the free movement of the instrument, by the escape of a few drops of urine, and by urgency to make water. If there be still some resistance before the instrument enter the bladder and it cannot be sunk lower, the part of the instrument projecting from the urethra must be gently raised, and the neck of the bladder thereby be somewhat depressed. 2044. The stone is in general found without much difficulty, if not very small, and if the patient be quiet; and when found, the instrument must be drawn a little back, without causing the least shock, and opened more or less, according to the size of the stone ; and then, first the outer canula, and afterwards the borer, are to be attached. At the same moment that the instrument is pushed a little forwards, the opened limbs of the forceps surround and grasp the stone, then the three-limbed canula is attached to it and fastened by the screw. By means of the scale fixed on the three-limbed tube, and by pushing the borer towards the stone, it is ascertained that the latter is actually fixed, and its size is made out. The frequent difficulty of grasping the stone may be rendered more easy by changing the patient's position, or by pressure on the region of the bladder. 2045. If the stone be very small, it may be at once pulled out. If it be very brittle, it often breaks by the closing of the forceps. But when this does not happen, the instrument should be laid into the hand-vice, and the borer moved against the stone by means of the bow, on which a dull or clear murmur is perceived. If the stone be in this way broken to pieces, all the pieces rarely fall out of its limbs, and the measure on the again retracted canula shows whether the piece grasped will pass through the urethra, or whether it must be still more broken. In the latter case, after the canula has been fixed, with the screw, the borer must be again em- ployed. The instrument is then to be slowly withdrawn by moving it gently from above downwards, and from right to left, observing the same direction as on its introduction. If in doing this there be still any obstacle, which is usually the case at the fossa navicularis, the borer must be again applied to the stone, to render it still smaller. The pieces in the bladder generally escape with the injected water, or with the urine through the enlarged urethra. If, however, the stone be firm, and the borer merely pierce without breaking it, the borer must, with certain intervals, operate only so long on the stone, till there is but a line from the tip of the forceps. Attempts must then be made either to give the stone another position, and operate with the borer on its other side, or if the patient be fatigued* the operation must be stopped. 2046. Jacobson's instrument is introduced just as a common catheter. Having reached the bladder, gentle movements are to be made with its beak to find the stone ; the instrument can also be twisted to the half of its long axis, so that its point may be directed against the back of the bladder, the handle of the instrument raised, pushed gently forwards and backwards, to one or other side, so as to sound every part of the bladder. CRUSHING, OR LITHOTRITY. 291 When the stone is found, the curved part of the instrument is to be laid on its side upon it, the moveable branch pushed forwards, so that the loop is formed within the bladder, and then by lateral movements of the instrument, or by correspondingly raising and sinking one part of the pelvis, attempts are made to bring the stone into the loop. When the stone is believed to be caught in its middle, the moveable branch is drawn somewhat back, so as to diminish the size of the loop. In order to break the stone now grasped, the screw is to be turned from left to right, as far as its length allows. If the stone be broken, the loop is to be again opened, and it is again attempted in the same way as at first, to grasp the single fragments, and to crush them, which must be repeated as often as any fragments are to be found for crushing, and the patient does not express any considerable pain. When the instrument is with- drawn, its moveable branch must be pushed sufficiently forward till it be completely closed, and if this be prevented by any fragment, the loop is to be repeatedly opened, and the instrument made to move in different directions, for the' purpose of getting rid of the fragments from the loop ; and then when the instrument is completely closed, it may be withdrawn like a catheter. The instrument is used in the same way for repeatedly crushing the stone fragments. 2047. Heurteloup's percuteur is introduced into the bladder like a catheter, and the stone searched for with it. The instrument is then opened by withdrawing its male branch, as much as the size of the stone requires, which then falls into the concavity of the female branch, almost of itself, or by some special movement, and is then caught by pushing down the male branch. The beak of the instrument is now brought into the middle of the bladder, the female branch held with the left hand, and a slowly increasing constant pressure made upon the end of the male branch with the right hand. The gradual driving forwards of the male branch, the sensation of crushing and the noise often accompanying the breaking up of the stone, as well as the sudden driving forwards of the male branch and the complete closure of the instrument, show the escape of the stone. If the pressure of the hand be insufficient for crushing the stone, more force by means of machinery, is employed, by which the results just mentioned are produced. If pressure with the hand be in- sufficient to break up the stone, the female branch of the instrument must be fixed with the hand-vice already mentioned, or to the proper apparatus on the bed, and the extremity of the male branch struck with light, equal, quick, and short blows of a hammer, so that the stone is gradually split and at last .completely smashed in pieces. When the male branch has been driven some way down, the hammering may be given up, and the further crushing effected by the hand or by the machinery. In this way is the operation to be continued till the male instrument has entered com- pletely, and tbe instrument is perfectly closed, by which the actual crush- ing, or the escape of the stone is shown. In the latter, as in the former case, the stone, or its pieces, must be again caught, and they must be crushed as already described, and the process repeated till the stone is completely broken to pieces, unless great urging to pass the urine, dis- eased contraction of the bladder, and discharge of the urine, violent pain, the patient's distress and the like, prevent the completion of the operation. 292 STONE IN THE BLADDER) After the fragments still clinging to the instrument have been got rid of, by pushing forwards, and pulling back its male branch, and by other gentle motions, and the instrument completely closed, it must be with- drawn by a gentle rotatory motion. If there be yet any obstruction from a little piece of stone between the branches of the instrument, it must be again pushed into the bladder, and attempts, as already mentioned, made to get rid of it, so that the instrument may be withdrawn completely closed. 2048. The duration of a lithotriptic sitting, depends on the sensibility of the patient and the symptoms it produces. In general, it occupies five or six minutes, but persons who are not very sensitive, can without in- convenience, bear it much longer. The symptom usually arising after the introduction of the instrument, is, violent urging to make water, which, however, often ceases, when the instrument is managed gently, or a few drops of urine have escaped. If a large quantity of urine be voided, and in consequence of other circumstances, the operation be still continued, it must be proceeded with only with the greatest caution and tenderness, on account of the great danger of injuring the walls of the bladder. 2049. After the operation, the treatment must be directed to the pre- vention and removal of the irritative and inflammatory symptoms, and the passage of the fragments of stone through the urethra. The patient must be kept quiet in bed, or the generative organs supported in a sus- pendor, and he should take only thin broth and mild mucilaginous drink, till no trace of irritation remain. But when this has completely ceased, he may gradually return to more and solid food, sit up, and go about for any length of time, but always having the generative organs supported. If febrile symptoms, inflammatory irritation and swelling of the mucous membrane of the bladder and urethra, of the prostate and generative organs, and of the inguinal glands occur, antiphlogistic treatment, suiting the degree and character of these symptoms, and the constitution of the patient, by general or local blood-letting, lukewarm baths, washes and internal treatment must be resorted to,. If with these symptoms, general coldness of the body, and wTeak, often very small pulse show a prostration of the powers, then dry rubbing, aromatic applications, the internal use of aromatic infusions, and even of volatile irritants, with due caution, must be employed. Inflammatory affections of other organs, which, although depending on the constitution of the patient, maybe excited by the operation, require the closest attention and corresponding treatment. 2050. The escape of sand and small portions of stone produced by the crushing, generally follows the first voidance of the urine, and is repeated each time it is afterwards passed ; accompanied with more or less burning sensation in the urethra, but without further irritation. Small fragments, even up to four lines, if they be round, do not in general cause any parti- cular symptoms; but if larger, hard and angular, they irritate and wound the mucous membrane of the urethra, excite inflammation, get fixed most commonly in the fossa navicularis, and producing difficulty in passing or entire retention of urine, excite the most violent and painful symptoms. This fixing of the fragments of stone in the urethra is very frequent, according to Leroy in four cases to one, and hence has arisen the great CRUSHING, OR LITHOTRITY. 293 number of instruments proposed for their removal. Often, however, even small pieces cannot be forced out, because either the bladder is paralysed or its neck is spasmodically contracted. 2051. To prevent this accident, various plans have been attempted to get rid of the fragments of stone from the bladder. Heurteloup with his lithocenose, a straight or curved steel canula, with two side openings and a hemispherical terminal piece introduced into the bladder, injects water, and allows it to flow out again. The small pieces escape with the water, the larger get entangled in the openings, and must then be broken up, either by the introduction of a solid tube, or with a toothed knob, which can be rotated (Leroy). This operation may be often repeated without removing the tube till its blind end is loaded with the fragments of the stone. Heurteloup also uses spoon-shaped forceps in form of his percuteur, and Leroy the small instrument of Jacobson, introduced through a canula. Schleiss (a) has for this purpose constructed an evacuating catheter, after the fashion of Heurteloup's percuteur, by which he can at the same time inject; and some have also employed Cooper's curved forceps. All the instruments, however, with which fragments are caught hold, of and drawn through the urethra are attended with danger of wounding, and injuriously irritating the urethra, in con- sequence of the projection of the angles of the fragments. 2052. Fragments of stone fixed in the urethra must be either thrust back into the bladder, or drawn out through the urethra, or removed by a cut into the urethra. The suitability of one or other of these modes of proceeding must depend on the seat of the lodgment of the fragment: if the piece of stone be fixed in the neck of the bladder, or if it have not passed the prostatic part, it is most easy and proper to push it back into the bladder, which may be done with a thick elastic or metal catheter, or by forcible injection into the bladder, so that, when the piece has been there pushed, it may be further crushed. When the fragment has penetrated into the membranous part, it often cannot be pushed back into the bladder, as the enlargement of the prostate in the urethra which frequently accompanies stone, opposes its return ; it is then more advisa- ble and necessary to pull it out: and the same practice must, be adopted in reference to fragments in the fore part of the urethra. 2053. A variety 6f instruments have been employed for withdrawing fragments of stones fixed in the urethra; some of these were known in old times, others have been proposed since the introduction of lithotrity, in consequence of the more frequent occurrence of this accident. The old instruments are, Lamotte's forceps, in shape of a snipe's bill; Hun- ter's or Hale's forceps ; Fabricius Hildanus's forceps; Pare's borer; that of Fischer for crushing the stone ; and Marini's metal loop. The latter instruments are, Hunter's forceps, modified with a moveable branch ; Cloquet's metallic loop, which is passed through a canula, and drawn together by means of a screw, so as to crush the stone when caught ; Colombat's figure-of-eight loop ; Jacobson's miniature instru- ment ; Cooper's curved forceps ; Amussat and Sagalas's small percu- teur; Civiale's hook; Leroy's three-limbed forceps, with or without a borer; Amussat's four-limbed forceps; Lerov's jointed curette, with (a) Above cited, pi. viii. f. 15, 17. 294 STONE IN THE BLADDER ; Dubowisky's modification, which has a borer added; Leroy's urethral forceps, with an articulated curette, and a percuteur with a curette; and Amussat's and Sanson's catheter furnished with a very large side open- ing- 2054. From the number of these instruments may readily be compre- hended the difficulty accompanying the withdrawal of the fragments of stone from the urethra. Their use always requires the greatest circum- spection and care. The straight or curved canular forceps of Hunter, Leroy, and others, are in general the most fitting, as are also Cooper's forceps, when the fragments are deeper seated in the membranous part of the urethra. Leroy's jointed curette, indeed commonly grasps the stone, but only moves, without drawing it out, if it be not also fixed or crushed by the borer. According to Pigne, Sanson has in several instances where he had in vain used the most suitable instruments, effected the withdrawal of stone by means of an elastic catheter, with one or two large side openings, with the greatest ease and without pain. The position of the fragment of the stone is first determined with a metallic catheter, which is then withdrawn, and an elastic catheter with its metal stem passed down to the fragment, shows its place a second time, by rubbing against it; the metal stem must then be drawn back about two inches, and by twisting the catheter, its opening must be endeavoured to be applied to the stone, which almost always at once gets into it, and is withdrawn with the catheter. If the fragment be quite close to the orifice of the urethra, it may, after slightly enlarging the orifice with a little cut downwards, (par. 2042,) be pulled out with a pair of common forceps. 2055. If a fragment of stone stick so fast in the urethra, that it can neither be thrust back into the bladder, nor pulled out, and if it be situated at an accessible part of the urethra, the coverings must be cut through, and the fragment removed through the wound. An elastic catheter must then be introduced into the bladder, and the wound per- fectly united. 2056. When after the escape of all the fragments of stone, no further symptoms appear, a close and careful examination of the bladder must be made, according to the rules already laid down, to be perfectly satisfied that there is no remnant of the stone, which may cause its reproduction. Prudence also requires that the examination should be repeated from time to time, before it can be ascertained that the patient is quite freed from the stone. 2057. Crushing the stone is effected in women in the same way, and according to the same rules as in men. The shortness, greater width, and extensibility of*the female urethra render the introduction and management of the instrument, as well as the withdrawal of large frag- ments of stone, easier. It must, however,, be remembered that on account of this very condition of the urethra, it is more difficult to retain the proper quantity of the injected fluid, and that the stone mostly lies on the sides of the bladder, on which account it may be more easily seized with curved than with straight forceps. The finger, however, introduced into the vagina can alter the position of the stone, and bring it to the instrument. CRUSHING, OR LITHOTRITY 295 Besides the works already quoted, the following may be referred to:— Civiale, Nouvelles Considerations sur la Retention d'Urine, suivies d'un Traite sur les Calculs urinaires, sur la maniere d'en connaitre la nature dans I'interieur de la vessie, et la possibilite d'n obtenir la destruction sans avoir recours a la Taille. Paris, 1823. 8vo.—Premiere Reclamation, 13 Fevrier, 1823.—Lettre au Chevalier Kern. Paris, 1827. 8vo.—Lettres sur la Lithotrite. Paris, 1828, 1831, 1833, 1837.—In Revue Medicale, 1826. vol. iv. p. 332.—1828. vol. i. p. 492.—1828. vol. iii. p. 97.—Archives generales de Medecine, vol. xii. p. 156.—Lancette, vol. iii. p. 369. 1820.—Gazette Medicale, vol. ii. p. 141. 1830.—Lettre sur la Litfiotrite Urethrale. 1831.—Mem. de l'Academie de Medecine, vol. iv. p. 243. 1835. Leroy d'Etiolle, Seance de l'Academie de Medecine, du 13 Juin, 1822.— Archives generales de Medecine, vol. i. p. 616. 1823; vol. iii. p. 396; vol. xii. p. 619.—Gazette de Sante. July, 182"2.—Journal Cornpl. des Sc. Med., vol. xiii. p. 214.—Lettre a Scarpa, ibid. vol. xxiv.—Journal generale de Medecine, vol. xcii. p. 287; vol. xciii. p. 282. 1825.—Lancette, vol. iv. p. 271. 1831.—Gazette Medicale, vol. iii. p. 365. 1831 ; Reponse aux Lettres de Civiale. 1831.— Memoires de l'Academie de Medecine, vol. v. p. 221. 1836. Amussat, Note sur la possibilite de sonder 1'Uretre de l'homme avec une sonde tout a fait droite, &c. Paris, 1822.^-Seance de l'Academie, 13 Janv., 1832.— Archives generales de Medecine, vol/tv. p. 31. p. 517. 1823 ; vol. xii. p. 146. 1826 ; vol. xvi. p. 110. 1827.—Journal Analytique, p. 385. 1829.—Lancette, vol. ii. p. 157. 1829.—Gazette Medicale, vol. ii. p. 71. 1830.—Table synoptique de la Lithotriptie. Paris. 1832. Heurteloup; in Archives generales de Medecine, vol. v. p. 150. 1824.—Re- ponse a. Civiale, ibid.; vol. x. p. 480. 1826.—Lettre a l'Acad. des Sciences. Paris, 1827.—Revue Medicale, vol. iii. p. 342. 1828.—Cases of Lithotrity, or Examples of the Stone cured without incision, &c. London, 1830. 8vo.—Lettre sur I'avantage de preferer la Percussion et la Pression. Paris, 1833. Cooper, Astley; in Med.-Chir. Trans., vol. xi. p. 358. 1820. Lukens ; in Philadelphia Journal, vol. i. p. 373. Brousseaud, Archives generales de Medecine, vol. x. p. 566. 1826. Murat, Rox, Gimelle, Rapport a l'Academie. 1825. Delattre, Quelques Mots sur le Broiement de la Pierre. Paris, 182o. Bellinaye, On the Removal of the Stone without cutting instruments. London, 1825. Harveng, Heidelberger klinische Annalen, vol. i. p. 424. Meyrieux; en Archives generales de Medecine, vol. x. p. 628. 1826. Kern, Bemerkungen fiber die Civiale and Leroy's che Methode. Wien, 1826. Desgenettes, Lettre a Scarpa; in Journal Complementaire, vol. xxiv. p. 36. 1826. Tavernier; in Journal de Progr&s, vol.ii. p. 174. 1827. Scheinlein; in Salzb. Med.-Chir. Zeitung., June, 1826. Seiffert, Ueber die franzosische Methode Blasensteine zu entfernen, u. s. w. Greifswalde, 1826. Magendie, Rapport a l'Institut, 1825; in Revue Medicale, vol. ii. p. 454. Lemaitre, Florian, Du Traitement de la Pierre; in Clinique, vol. ii. p. 282. 1828. Fournier, (de Lempdes,) Lithotritie perfectionnee. Paris, 1829. Rigal; in Clinique Universelle, vol. i. p. 231.—Archives generales de Medecine, vol. xxi. p. 459. 1829.—Lancette, vol. ii. p. 176. 1829.—Brochure sur la Litho- tritie. 1829. Pamars, Lithotriteur courbe; Clinique, vol. i. p. 231. 1829. Bancal, Manuel pratique de la Lithotritie. Paris, 1829. Dumeril, Rapport a l'Institut; in Revue Medicale, vol. iv. p. 482. 1829. Drouineau, Consideration sur la Lithotritie; These. Paris, 1829. Blandin, Journal Hebdomadaire, vol. iii. p. 193. 1829. vol. vi. p. 301. 1830. Waenker, Ueber den praktischen Werth der Lithotritie. Freiburg, 1829. Jacobson; in Hamburg. Magazin der ausl. Heilk. 1830. Pravaz, Lithotriteur courbe; in Archives generales, vol. xxii. p. 256. 1830.__ Lithotriteur droit, in same, p. 413.—Gazette Medicale, vol. ii. p. 207. 1831. 296 CUTTING FOR THE STONE, OR LITHOTOMY J Tanchou ; in Archives generales, vol. xxiii. p. 300. 1830. Thiaudiere, These sur la Lithotritie. Paris, 1830. Dollez, These sur la Lithotritie. Paris, 1830. Demetrius, These sur la Lithotritie. Paris, 1831. Segalas, Observations de Lithotritie. Paris, 1831. Benvenuti, Essai sur la Lithotritie. Paris, 1833. Blandin, De la Taille et la Lithotritie. Paris, 1834. [Randolph, N. R. Smith & Gibson in the Am. Journ. of Med. Sci. vols. 15, 18 and 19.—g. w. n.] Begin, Dictionnaire de Medecine et de Chirurg. prat., vol. xi. p. 113. 1834. Caffe, Journal de Connaissances Medico-ChirurgicaleS. Sept. 1835. von Wattmann, Ueber die Steinzerbrechung und ihr Verhaltniss zum Stein- schmitte. Wien, 1835. Doubovitzki, Reproduction fideles des Discussions qui ont eu lieu sur la Litho- tripsie et la Taille a l'Acad. de Medec. Paris, 1835. Hecker, Die Indicationen der Steinzertriimmerungsmethode. Freiburg, 1836. Charriere, Catalogue des Instrurnens destines a l'Operation de la Lithotritie. Paris, 1838. Graf; in Oestereich. Medic. Wochenschrift, 1841. OF CUTTING FOR THE STONE, OR LITHOTOMY. (Lithotomia, Cystotomia, Lat.; Steinschniite oder Blasenschnitte,Ge,Tm.', Taille, Fr.) Schaeffer, Dissert, de variis Lithotomiae generibus. Argent, 1724. Le Dran, F. H., Paralleje des differentes manieres de tirer la Pierre hors de la Vessie. Paris, 1730. ------Supplement au Parallele. Paris, 1757. Le Cat, C. L., Recueil de Pieces sur l'Operation de la Taille, Part I. Rouen, 1749; Part II. 1752; Part III. 1753. Pallucci, N. L, Lithotomie nouvellement perfectionnee; avec quelques Essais sur la Pierre et les moyens d'en empecher la formation. Paris, 1757. 12mo. Dubut, (Praes. Ferrand,) De variis Lithotomiee methodis. Paris, 1771. Morand, Salvat.,- Opuscules de Chirurgie, part ii. ------, Eloge de M. Cheselden; in Mem. de l'Acad. Roy. de Chirurgie, vol. iii. Louis, Rapport des Experiences faites par l'Academie Royale de Chirurgie sur differentes methodes de tailler; in Mem. de l'Acad. de Chir., vol. iii. p. 623. Sammlung auserlesener, zur Geschichte und Ausiibung des Blasensteinschnittes gehoriger Abhandlungen; mit Kupfern. Leipsig, 1784. Hartenkell, Tractatus de Vesicae Urinaria? Calculo. Bamb. et Wirceb., 1783. Earle, Sir James, Practical Observations on the Operation for the Stone. Second Edition. London, 1796. Deschamps, Traite historique et dogmatique de l'Operation de la Taille. Paris, an iv. 4 vols.; avec un supplement, dan lequel I'histoire de la Taille estcontinuee, depuis la fin siecle dernier jusqu'a ce jour; par. L. J. Begin. Paris, 1826. Schuler, Antiquitates Lithotomiae. Hal., 1797. Thomson, Observations on Lithotomy. Edinburgh, 1808. Allan, Robert, Treatise on the Lithotomy. Edinburgh, 1808. fol. Dupuytren, G., Lithotomie. Paris, 1812. Mechlin, A., Dissert. Apercu historique et pratique sur l'Operation de la Taille chez l'Homme. Strasbourg, 1822. 4to. von Kern, V., die Steinbeschwerden der Harnblase, ihre verwandten Uebel und der Steinschnitt bei beiden Geschlechtern. Wien, 1828. 4to. Dupuytren, Memoire sur l'Operation de la Taille, acheve par Sanson et Begin. Paris, 1826. Bassow, B., Diss, de Lithiasi vesicae urinariae in genere et in specie de retractione Calculi per sectionem perinaei; cum tab. ix. Mosquae, 1841. TREATMENT PREVIOUS TO OPERATION. 297 2058. The operation of cutting for the stone consists in the artificial opening of the bladder or of its neck, at some one part, and to such extent as will allow the removal of the stone. This operation should always be undertaken as soon as possible, because otherwise the stone enlarges, and renders the operation proportionally more difficult and dangerous. It is, however, contraindicated in severe continued pain in the kidneys, which depends either on stone, suppuration, or other destruc- tion of those organs ; in ulceration of the bladder, which may be dis- tinguished from its simple blennorrhagic affections; in considerable thickening or carcinomatous degeneration of its walls; also when the powers are very low sunk, and there has been previous wasting fever; in great enlargement of the stone: and, finally, in its being completely encysted. The operation must be deferred if there be any accidental or passing disease, if great inflammation of the bladder and its neck, if much sympathetic irritation of the digestive organs, continued uneasi- ness, vomiting, and the like, as also if there be stricture of the urethra, untill the passage be restored. The circumstances which contraindicate cutting for the stone require close and careful consideration, as experience frequently shows that, even under the most unfavourable circumstances the operation is successful, and that with the removal of the stone, the symptoms depending on its presence, as for example, the chronic in- flammatory affection of the bladder, cease. If it be well ascertained that the stone is encysted, it being perfectly so, must decidedly contraindicate the operation, as in most cases it is impossible to set such stone free, or the case may terminate fatally. An enormously large stone can only be considered as contraindicating one special mode of operation. Cases may occur, though very seldom, in which, though the presence of a stone in the bladder is proved by sounding, few or no symptoms occur; its enlargement is very gradual, and the operation does not seem to be necessary. It is always, however, to be feared, that in deferring the operation till the appearance of symptoms which require it, such changes may accrue as will render its result doubtful. This especially applies to young persons; as, on the contrary, in old per- sons, the operation must be considered to be contraindicated (1). [(1) "The age of the patient," says Astley Cooper, "does not much influence the result of the operation, with the exception I shall mention. Old age is not to be a bar to it if, so far as the stone will permit, the patient be active and have no other complaints. Mr. Cline, senior, operated successfully upon a patient at eighty-two; Mr. Attenburrow, of Nottingham (2), at a still more advanced age. I operated on a gentleman aged seventy-six, and he died about ten years after. About sixty years of age is the period at which stone is most frequent in the adult, and then the opera- tion is very successful. In the middle period of life, fever is more violent from the operation, and the patient is often too much loaded with fat to be submitted to it. Fat persons do not generally bear operations well; they have little vital power; they should be reduced by diet and medicine; and they must be accustomed to irritation of the bladder, by the frequent introduction of the sound; but still they have more fever and disposition to peritonaeal inflammation than at a later period of life. The age at which there is least danger is from three to twenty, for death is then a very rare occurrence. Under the age of two years, children often become convulsed, and die from the operation, on account of their excessive irritability." (pp. 244, 45.) (2) His son informs me that this patient was eighty-five years old; and that his father had also operated on a man of eighty-seven, who lived to the age of ninety-five. The earliest age at which I have known the operation for stone performed with success was twelve months, in two instances successfully by Keate, at St. George's Hospital. John Hunter operated on a child of eighteen months, but the result is not stated. I have recently cut a child of twenty months, but he died on the four- teenth day of peritoneal inflammation, accompanied with small abscesses in the irn- Vol. iii.—26 298 CUTTING FOR THE STONE IN MEN; mediate neighbourhood of the wound. Civiale (a) has, however, collated many instances of infants affected with stone, one of which was cut at ten weeks, but with what result is not stated. , Although fat persons are not very favourable subjects for stone-operations, yet with management they may do well. My friend Green cut a man about fifty, who a short time before the operation weighed eighteen stone, but had been reduced, and the girth of whose waistcoat was nearly two yards. He did well of the operation, but stone formed again; he was lithotritized, and died with inflammation of the mucous membrane of the bladder.—j. f. s.] 2059. If the stone-patient's health be otherwise good and his mode of living regular, it will be sufficient preparation for the operation to diminish, a few days previously, the ordinary quantity of his diet, to bathe him several times in lukewarm water, and for the two immediately pre- vious days to restrict his diet further, and to give clysters. In full- blooded persons, one or two bleedings should be resorted to; in haemor- rhoidal affections and especially with loading of the liver, leeches must be applied to the anus. In stout persons, with weak constitution, the condition of the juices and the state of the bowels must be attended to, as this kind of constitution may be most prejudicial to the result of the operation. Under these circumstances bathing must be used with the greatest caution, and tonics are often called for. The use of purgatives, commonly employed in the preparatory treatment to cutting the stone, requires care; if necessary, at least a few days must intervene between their use and the operation. If the patient have worms, they must either be first got rid of, and then the operation be performed; or he may be left to his ordinary quantity of diet, attention being paid to its quality, and on the day before the operation have broth three or four times, according to his appetite, and on the morning itself, bread soaked in beef tea or rice porridge. Old persons are to be treated in the same way. In country people, who are accustomed to coarse food, a quick change of food, and to a lighter kind, may be unfavourable to the result of the operation. In very sensitive subjects, small doses of opium, extract. hyoscyami, or aq. lauro-cer., may be administered. A.—Of Cutting for the Stone in Men. 2060. The history of cutting for the stone presents six different modes in which it is performed on the male, to wit: — First, Cutting with the little apparatus. Second, ,, ,, great ,, Third, „ ,, high operation. Fourth, „ by the lateral ,, Fifth, ,, into the body of the bladder from the perineum. Sixth, ,, through the rectum. 2061. Cutting for the Stone with the Little Apparatus {Apparatus parvus, Hypocystomia, Lat.; der Steinschnitt mit der kleinen Gerdthschaft, Germ.; la Tuille par le petit Appareil, Fr.,) called also Celsus's method, because he first described it, consists in making a cut upon the stone through the perineum and neck of the bladder, and drawing it out with a stone-spoon. This plan remained the only one, and unchanged up to the sixteenth century, when it yielded to the great apparatus, and was ( quite so low, cuts through the m. transversus perinei com- pletely, and the m. levator ani partially. If by this the membranous part of the urethra be not laid bare, so that the groove of the catheter can be distinctly felt by the forefinger of the left hand, that finger is to be placed with its volar surface towards the patient's right side, at the upper angle of the wound, and near to it the part still covering the membranous part are to be divided. At this place I generally press the bistoury on to the staff, thrusting it in the direction as if I would push it up behind the pubic symphysis, and then complete the cut by carrying the knife down- wards (1). If the outer cut be begun higher than directed, there is danger of wounding the bulb of the urethra, and the transverse artery of the perinaeum. Continuing the cut lower endangers either the rectum, or, if the cut be made too much outwards, the internal pudic artery. Rheineck (a) always makes the cut on the right side, which has no advantage, and is only proper if the patient must be cut on the right side (b), which may be the case if the rectum, instead of being directly behind the prostate, be on its left side (c). [Brodie directs that the staff be " held nearly perpendicularly, the handle of it being, however, a little inclined towards the patient's right groin. This causes the convexity of the instrument to project slightly on the left side of the perinaeum. In the first part of the operation, your attention is to be directed to the staff. You are to feel it with your left hand, and the knife, held in your right hand, is to be directed towards it. It is a sure guide, following which, you can never err, even in the deepest perinaeum. * * * Where there is any quantity of fat in the perinaeum, or any thing even distantly approaching to what we call a deep perinaeum, if you attempt to cut at once into the groove of the staff, the result is, that you open the urethra too far forwards ; you divide the corpus spongiosum of the pern's, which need not in reality be divided at all; and you are then certain of wounding the artery of the bulb of the urethra, which otherwise is in most instances avoided. Another in- convenience which attends on this method of proceeding is, that the wound being too near to the scrotum, the cellular membrane of it is in danger of being infiltrated with blood; and another still is, that a greater mass of substance is left to be divided, when you continue the incision into the bladder, than there would have been if you had cut into the urethra further back in the first instance. I say, then, let the open- ing in the urethra be made deep in the perinaeum, behind the bulb, and as near as can be to the prostate. Place the thumb-of your left hand on the skin over the staff; and in a man of ordinary size, about an inch and a quarter before the anus. Begin your incision immediately below this, on the left side of the raphe, and continue it backwards and towards the left side, into the space between the anus, and the tube- rosity of the left ischium. Here you may cut freely; you can injure nothing of consequence. Then feel for the staff in the wound ; direct the point of your knife towards it, and carefully cut into the groove, where it lies in the membranous part (a) Medic, und Chirurg. Betracht. iiber die (b) Klfin ; in Loder's Journal, vol. iv. p. einfache Methode des Seitenblasenschnittes; 255. mit einer Vorrede von C. L. Mursinna. Ber- (c) Deschamp's, above cited, vol. iii. p. 89 Un, 1815. Obs. 163, 169. 312 CUTTING FOR THE STONE ; of the urethra. All these incisions are made low down in the perinaeum, that is, near the rectum." (pp, 309, 10.) A free cut through the skin, proportioned to the patient's size, is always very advantageous, as it materially facilitates the withdrawal of the stone, if it be large, and prevents much bruising, which is an object of great importance. I have seen both small and large external cuts made, and am sure that the latter are preferable to the former, although I am not inclined to make the eut so large as to be able to see through it into the bladder, as was jokingly said of the operations of Chandler, who was a very good and quick lithotomist, and one of the surgeons at St. Thomas's Hospital during my studentship. It is not the first cut which can wound the rectum, except with excessive carelessness, but the second, and then it may easily be pre- vented if the surgeon keep the point of his knife raised towards the pubic arch, in- stead of depressing it towards the rectum, as is too frequently done.—j, f. s.] 2079. The opening of the membranous part of the urethra, and the cutting into the neck of the bladder, is that act of the operation by which the several modes of performing the lateral operation for the stone are distinguished. These may be arranged under the following divisions:— First, the cut into the neck of the bladder made with the same knife used for the outer cut; Second, with some special instrument for the purpose, and from without inwards; Third, with a special instrument from within outwards. . [(Scarpa (a) has made the following important observations in reference to the division of the prostate in the lateral operation, whether performed with the knife or with the gorget:—" As the apex of the prostate gland forms the greatest resistance to the introduction of the forceps and the extraction of the stone, this part of it ought, in every operation of lithotomy in the perinaeum, to be completely divided. But with respect to the body and base of the gland, an incision, extending to the depth of five lines, through its whole length, and consequently including a small portion of the orifice of the bladd-er, is, with the aid of a moderate and gradually increased dilatation, sufficient for the extraction of a stone of more than ordinary size, without the parts through which it passes being greatly contused or lacerated. In children, where the orifice of the bladder and base of the prostate gland are easily distended, and in aged persons, in whom the orifice of the bladder, and neck of the urethra are generally much larger than in adults, an incision in the*base of the gland less than five lines in depth, and in children, of two only, is sufficient for the extraction of a stone of ordinary size, by means, of a moderate dilatation of those parts. The large size of the stone, for instance, of one exceeding twenty lines in its smallest diame- ter, is no sufficient ground for dividing the substance of the gland to such an extent as to penetrate into the cellular membrane beyond it and the fundus of the bladder; for as an incision of such depth is constantly followed by the infiltration of urine, gangrenous abscesses, and fistula, between the bladder and rectum, it is obvious that calculi of such size ought never to be extracted by the perinaeum. The lateral operation has therefore limits beyond which it is impossible to pass without exposing the patient to more serious evils than those which coujd arise from the presence of the stone in the bladder." (p. 7-9.)] 2080. The cut into the neck of the bladder, made with the same knife. To this belong the methods of Franco, Frere Jacques, Rau, Chesel- den, Morand, and others, and as it has been more or less modified and employed in recent times by Dubois, Klein, Langenbeck, and Kern. When the outer cut is made, and the membrano.us part laid bare, either the point of the bistoury is introduced on the nail of the left forefinger, which rests on the groove of the staff, into it, or the point of the knife is thrust directly into the groove of the staff, behind the top of its curve, also behind the symphysis, in a direction as if it were to come out at the (a) Memori.i sul conduttore taglienti d'HAWKUSS per 1'estraiioue delfa Pietra della Vesica.. Pavia, 1825. Translated by Briggs. THE LATERAL OPERATION WITH THE KNIFE. 313 first lumbar vertebra. The staff is now taken with the left hand from the assistant, brought in a parallel direction to the Unea alba, pressed towards the symphysis, and the knife, held with the whole hand, is thrust into the groove of the staff, according to the direction of the outer wound, up to the blind end of the staff, and then in drawing out the knife, its handle being a little raised, the inner cut is enlarged. A common somewhat convex bistoury serves the purpose in this method, but the most suitable is a particular knife, the convex blade of which is connected firmly with a rather long handle, as the knives of Cheselden (a) and Dubois (b). Le Dran (c), after having made the cut through the skin and urethra, introduced a director with a beak (sonde a bee) upon the groove of the staff into the bladder, and having withdrawn the staff examined the stone with the director to ascertain its size, and then thrust a convex bistoury (bistouri h rondache) into the bladder upon the groove, turned downwards, of the director. Daunt's method is similar, in which, after opening the membranous part of the urethra, and introducing a director, or lithotome furnished with a tongue, was pushed in sideways (Dease) (d). In a similar manner Muter (e) operates; after opening the membranous part, another staff is introduced upgn tne former, and with it a sickle-shaped knife, and in drawing the knife out, the neck of the bladder is cut into. Pouteau (/) is a modification of Le Dran's method. Key (g) employs merely a staff with a very short curve, and aconvex bistoury (1). Klein's (h) method is peculiarly distinguished by his using a common bistoury, and he not only always cuts completely through the prostate gland, but always also the bladder itself. von Kern (?) places the nail of the left thumb in» the groove of the staff, and retains it there whilst he carries the knife to the blind extremity of the staff. Guerin's (.j) method may be here mentioned, which, however, has but historical interest. [(Key's operation (k) is performed with a straight staff, of which the point is curved slightly upwards to the extent of an inch, so as to avoid its catching in any projecting fold of the bladder, and its groove deeper than in the common staff, to prevent any risk of the knife slipping out. His knife, in form, resembles a common scalpel, but is longer in the blade, and slightly convex in the back near the point, to enable it to run with more facility in the groove of the director. Operation.—"An assistant holding the director with the handle somewhat inclined towards the operator, the external incision of the usual extent is made with the knife, until the groove is opened, and the point of the knife rests fairly in the director, which can be readily ascertained by the sensation communicated; the point being kept steadily against the groove, the operator with his left hand takes the handle of the director, and lowers it till he brings the handle to the elevation (a) Douglas, Appendix to the History of (h) Chirurg. Beobacht., p. 1. Stuttgart, the Lateral Operation for the Stone, con- 1801.—Praktisehe Ansichten der bedeutend- taining Mr. Cheselden's present method of stem Operationen, pt. ii. Stuttgart, 1816. performing it. London. 1731. (i) Above cited. (b) Above cited.—Chelius's alteration of (j) Memoire sur l'Operation de la Taille; Dubois' knife; in Wehr, Dissert, de Litho- in Recueil des Actes de la Societe de Lvon, tomia laterale, Heidelberg, 1836. p. 390, vol. ii. 1801.—Treyrran, Parallele (c) Traite des Operation, p. 307. Paris, des diverses Methodes proposees pour l'ex- 1742. traction des Calculs vesicaux par l'appareil (d) Essay on Hydrocele. laterale &c. Paris, 1802.—Chrestieen, Dis- (e) Practical Observations on the Lateral sert. de Nova Lithotomia Guerini. Erlang. Operation of Lithotomy, and on the various 1804,—Michaelis, Etwas uber den Blasen- and new modes of performing this Opera, steinschnitt. Marburg, 1813, tab ii.—Klein. tion, &c. 1824; with plates. Ueber Guerin's Instrument znm Blastn- (/) Taille an niveau. Avignon, 1765. schniit; in Chiron., vol. ii. part ii. pi. vi. f.— pi. i. ii. 1-6.—Montagxa ; in von Graefe und von (g) A short Treatise on the Section of the Walther's Journal vol. iv.p. 507, pi. vi. f. Prostatic Gland in Lithotomy, &c. Lon- 3-6.—Smith, in Baltimore Med. and Surg. don, 1824. 4to.; with plates. Journ. and Rev. 1834, April, p. 13. (k) Short Treatise, above cited. 27* 7 314 CUTTING FOR THE STONE ; described in PL iii.,* keeping his right hand fixed ; then withaa ea9y simui'taneons movement of both hands, the groove of the director and the edge of the knife are to be turned obliquely towards the patient's left side; the knife having the proper bearing is now ready for the section of the prostate; at this time the operator should look to the exact line the director takes, in order to carry the knife safely and slowly along the groove, which may now be done without any risk of the point slipping out. The knife may then be either withdrawn along the direetor, or the parts further dilated, according to circumstances. Having delivered his knife to the assistant, the operator takes the staff in his right hand, and passing the forefinger of his left along the director, through the opening in the prostate, withdraws the director, and ex- changing it for the forceps, passes the latter upon his finger into the eavity of the bladder. In extracting the calculus, should the aperture in the prostrate prove too small, and a great degree of violence be required to make it pass through the opening, it is advisable always to dilate with the knife, rather than expose the patient to the inevitable danger consequent on laceration." (p. 28-30.) Liston (a) uses a curved staff, and a long straight knife slightly convex towards its point. He " enters the knife freely into the perinaeum, about an inch more or less behind the scrotum, and makes it cut downwards and outwards through the skin and superficial fascia, in a line about midway betwixt the tuberosity of the ischium and the anus, and beyond that orifice towards the'sacjo-ischiatic ligament. The forefinger of the left hand is then placed in the bottom of the wound, about its middle, and directed upwards and forwards; any fibres of the transverse muscle or of the levator of the anus that offer resistance, are divided by the knife, with its edge turned downwards ; the finger then passes readily through the loose cellular tissue, but is resisted by the deep fascia, immediately anterior to which the groove of the staff can be fek thinly covered.. The point of the instrument is slipped along the nail of the finger, and, guided by it, is entered into the groove at this point, with its back still directed upwards. The finger all along is placed so as to depress and protect as much as possible the coats of the rectum. The same knife, pushed forwards, is made to divide the deep fascia, the muscular fibres within its layers, and a. very small portion, not more than two lines, of the urethra anterior to the apex of the prostate, together with the prostatic portion of the canal and the gland, to a very limited extent. The-external incision eannotbe too free within certain bounds. * * * But the internal incision must be very limited indeed; it should certainly not extend beyond six or seven lines from the urethra, outwards and downwards; for the less that is cut, the greater will be the patient's safety. * * * The object in following this method, is to avoid all interferenee with the reflection of the ilio-vesical fascia, from the sides of the pelvic cavity over the base of the gland and side of the bladder. If this natural boundary between the external and internal cellular tissue is broken up, there is scarcely a possibility of preventing infiltration of urine, which must almost certainly prove fatal. The prostate and other parts-around the neck of the bladder are very elastic and yielding, so that without much solution of their continuity, and without the least laeeration, the opening can be so dilated as to admit the forefinger readily ; through the same wound the forceps can be introduced upon this as-a guide."—(p. 508-11.) Cheselden's Qperalioti. Cheselden's operation for the stone, his "lateral way," as he calls it, has much perplexed writers on this subject. Cheselden himself has distinctly given two modes in which he performed this operation; the first described in the Appendix to the fourth edition of his Anatomy of the Human Body, 1730; and the second in the Appendix to the fifth edition, 1740; seventh edition, 1750; which was the last published in his lifetime, as he died in 1752; and, I presume, also in the sixth, though I have not had an opportunity of consulting this. In 1731, Dr. James Douglas published an Appendix to the History of the Lateral Operation for the Stone, containing Mr. Cheselden's present method of performing it. 4to. This (a) Practical. Surgery. Fourth Edition. * This is the only direction laid down as to the position of the stafiyand I am sorry I am unable to give it more precisely..—j* e. s. THE LATERAL OPERATION (CHESELDEN'S.) 315 differs remarkably fron* Cheselden's account in his fourth edition; but it is the same precisely, though more fully detailed, as in Cheselden's fifth and seventh editions; and, therefore, although Dr. Yelloly's (a) observation is perfectly correct, that " the least consideration will show that this (Douglas's) account of Chesel- den's improved operation is perfectly irrecpncilable with that which is given by Cheselden himself, in the Appendix to the fourth edition of his Anatomy, or by Mr. Morand, with his sanction and authority," yet the comparison of the fourth and fifth editions, will prove that Douglas's statement is correct, and not " the absurd statement," nor "an operation which it is next to impossible to perform," as it has been designated by a highly distinguished surgeon of the present time. Cheselden's instruments were a staff, knife, and blunt gorget with a beak. The staff, including its handle and straight stem, measured six inches and a quarter in length, and to its extremity joined the grooved part five inches and a half more. " The sulcus or groove is remarkably deep and wide, the edges smooth and blunt— one end of it reaches a little way down on the handle, and the other, ending in an obtuse point, is without any check, as is seen in your common staffs. This part may again be divided into a curved portion and a straight rostrum or beak. The curvature next the handle not very great, and extends but a little way back from it; and from the extremity thereof, the long rostrum projects almost directly for- wards." (6). This statement of the curve and the length of the beak of the staff is important, as it will be seen in Cheselden's operation that there could not be any difficulty in introducing the gorget, as it would run at once into the bladder in a horizontal direction from the external wound, without depressing,the handle of the staff, which depression is requisite as the operation is now performed, whether the common curved or straight staff be used. The other instruments need no notice. Cheselden thus describes his operations, the commencement of which in the editions of 1730 (fourth) and 1740 (fifth) are alike, almost word for word :—"This operation I do in the following manner:—I tie the patient as for the greater appa- ratus, but lay him upon a blanket several doubles upon a horizontal table three feet high, or a little more, with his head only raised. I first make as long an incision as I well can, beginning near the place where the old operation ends, and cutting down between the musculus accelerator urines and erector penis and by the side of the intestinum rectum ; I then feel for the staff." Thus far the two editionsare the same; but now comes the important difference:— Fourth Edition, 1730. Fifth Edition, 1740. " and cut upon it the length of the prostate gland strait on to the bladder, holding down the gut all the while with one or two fingers of my left hand. The rest of this operation is the same as in the old way." (p. 344.) "holding down the gut all the while with one or two fingers of my left hand, and cut upon it in that part of the urethra which lies beyond the corpora cavernosa urethras, and in the prostate gland, cutting from below upwards, to avoid wounding the gut." (p. 330.) Such are Cheselden's own words, and the only difference between the operation of 1740 and Dr. James Dsuglas's description is that it is more explicit; and, in his preface, he says :—"I am obliged to Mr. Cheselden for the chief materials of this paper; it was impossible to draw it up to good purpose without him ; and since he has been so kind as to communicate to me, with the greatest readiness and without reserve all the particulars-which I could not otherwise have come to the knowledge of, I am confident that none will pretend to dispute but what I here describe is his operation, and his whole operation." The following is the important part of Douglas's description of the operation of Cheselden's fifth edition :—After having detailed the first incision, he says that Cheselden " having cut the fat pretty deep, especially near the intestinum rectum, covered by the sphincten and levator ani, he puts the forefinger of his left hand into the wound, and keeps it there till the internal incision is quite finished ; first to direct the point of his knife into the groove of his staff, which he now feels with the end of his finger, and likewise to hold down the intestinum rectum, by the side of which his knife is to pass, and so prevent its being (a) Med.-Chir. Trans., vol. xv. p. 347. (6) Douglas's above cited, p. 4. 316 i CUTTING FOR THE STONE ; wounded. This inward incision is made with more caution and more leisure than the former. His knife first enters the groove of the rostrated or straight part of his catheter, through the sides of the bladder, immediately above the prostata, and after- wards the point of it continuing to run in the same groove in a direction downwards and forwards, or towards himself, he divides that part of the sphincter of the bladder that lies upon that gland, and then he cuts the outside of one half of it obliquely, according to the direction and whole length of the urethra that runs within it, and finishes his internal incision by dividing the muscular portion of the urethra on the convex part of his staff. When he first began to practice this method, he cut the very same parts the contrary way; that is, his knife entered first the muscular part of the urethra, which he divided laterally from the pendulous part of its bulb to the apex, or first point of the prostate gland, and from thence directed his knife upward and backward all the way into the bladder; as we may read in the Appendix he lately published to the fourth edition of his Book of Anatomy. But some time after he observed, that in that manner of cutting, the bulb of the urethra lay too much in the way; the groove of the staff was not so easily found, and the intestinum rectum was in more danger of being wounded." (pp. 12, 13.) In further proof of the correctness of Douglas's statement, Sharp (a), in speaking of Rau's operation for the stone, and Cheselden's first mode of proceeding in his lateral operation of 1730, says:—"After this unsuccessful trial, Mr. Cheselden made use of the following method, which is now the practice of most English ope- rators. The patient being laid on a table, &c. This (the external) wound must be carried on deeper between the muscles, till the prostate can be felt, when search- ing for the staff, and fixing it properly if it has slipped, you must turn the edge of the knife upwards, and cut the whole length' of that gland from within outwards, at the same time pushing down the rectum with a finger or two of the left hand, by which precautions the gut will always escape wounding." (pp. 99, 100.) And in contrast with this, speaking of " the old way, in which the urethra only is wounded about two inches on this side the prostate, and the instruments are forced through the rest of the passage, which is composed of the bulbous part of the urethra, the membranous part of the urethra, the neck of the bladder, and the prostate gland," he observes:—" It is pity, the operators do not in the old way always slide the knife, along the groove of the staff, till they have quite wounded through the length of the prostate." (pp. 104, 105.) The remainder of the operation, as described in the fifth edition, are Cheselden's own words:—" And then passing the gorget very carefully in the groove of the staff into the bladder, bear the point of the gorget hard against the staff, observing all the while that they do not separate, and let the gorget slip to the outside of the bladder; then I pass the forceps into the right side of the bladder, the wound being on the left side of the perinaeum; and as they pass, carefully attend to their entering the bladder, which is known by their overcoming a straitness, which there will be in the place of the wound; then taking care to push them no further, that the bladder may not be hurt. I first feel for the stone with the end of them, which having felt, I open the forceps and slide one blade underneath it, and the other at the top; and if I apprehend the stone is not in the right place of the forceps, I shift it before I offer to extract, and then extract it very deliberately, that it may not slip suddenly out of the forceps, and that the parts of the wound may have time to stretch, taking great care not to gripe it so hard as to break it; and if I find the stone very large, I again cut upon it, as it is held in the forceps. Here I must take notice, it is very convenient to have the bladder empty of urine before the operation; for if there is any quantity to flow out of the bladder at the passing in of the gorget, the bladder does not contract but collapse into folds, which makes it difficult to lay hold of the stone without hurting the bladder, but if the bladder is contracted, it is so easy to lay hold of it, that I have never been delayed one moment unless the stone was very small, (pp. 330, 31.) Douglas also gives an account of the dissection of the parts concerned in this operation, which, he says, "I have had several good opportunities of examining in dead subjects, upon which Mr. Cheselden was so kind as, at my request, to perform his operation. I once likewise opened the body of a patient who had been cut by him for the stone, in which I found the parts divided in the very same manner in (a) Treatise on the Operations of Surgery. London, 1751. Sixth Edition. THE LATERAL OPERATION (CHESELDEN'S.) 317 which they were cut in the dead bodies I had dissected." The parts he cuts are first, the common integuments of the perinaeum, and a little further back, between the protuberance of the os ischium and extremity of the os coccygis. * * * Second, he divides sometimes the subcutaneous portion of the sphincter ani. * * * Seventh, he divides in a pretty oblique direction, a large portion of the levator ani that lies on the inside of the ligamentum pubis transversum, &c." These are some of the prin- cipal parts; but as Mr. Cheselden does not always make his outward wound pre- cisely in the same place," they need not be further noticed. "The internal wound is through the bladder, prostate gland, and urethra. First, The vesica urinaria, covered with the membrana cellularis is cut in two places, viz., first, a small portion of it a little above the prostate gland ; on the left side, where he enters the knife first into the groove of his staff, and then part of the bladder which lies round the orifice upon the upper part of that gland ; second, the substance of one-half of the prostate gland is likewise divided laterally from without, inwards, in the direction of the urethra that lies within it, through the whole length of that part of the canal; third, the iter urinae, or canal of the urethra, is divided in two places, and both laterally : first, the beginning of it, which runs through the substance of the prostate lengthways, at the same time the incision is made through it, and the urethra into the groove of the staff. The next is the membranous part of the urethra, with the circular muscle that surrounds it beginning at the apex inferior of the prostate, and ending a little beyond the hole in the septum tendineum, under the pendulous part of its bulb. * * * To this short enumeration of the parts, one observation may be added, which is, that if the operator turns the edge of his knife too far backwards, and then raises it to cut, he can scarcely be able to avoid wounding the intestinum rectum pretty high, some part of the vesiculae seminales next the prostate, and the verum montanum within the urethra that runs through that gland, together with a large portion of the levator ani anterior and of the ligamentum suspensorium vesicae, that closely embrace it." (p. 21-5.) The celebrated Martineau, of Norwich, followed pretty nearly Cheselden's operation of 1730, using the knife and blunt-beaked gorget, the latter being em- ployed, to use Crosse's words, "as a conductor, and also as a dilator of the blad- der." (p. 75.) Martineau (a), describing his own operation, says he used "a staff in which the groove was much wider and deeper than usual, and therefore more easily felt; * * * he made his first incision long, deep, and nearly in a line with the raphe, which, he thought, facilitated the cure; he then felt for the groove, and intro- duced the point of the knife into it as low down as he could, and cut the mem- branous part of the urethra, continuing his knife through the prostate into the blad- der; when, instead of enlarging the wound downwards, and thus endangering the rectum, he turned the edge of the blade towards the ischium,, and made a lateral enlarge- ment of the wound in withdrawing the knife; he thus avoided cutting over, and over again, which often does mischief, but can give no advantage over the two incisions, which he generally depended on, unless in very large subjects, where a little further dissecting may be required. He then took the staff in his left hand, whilst he in- troduced the blunt gorget with his right, and by thus taking the management of the staff and gorget into his own hands, he better directed the latter, and discovered at once if it were slipping from the groove; but this will be prevented by depressing the gorget while it is pushing on towards the bladder. On this depends very often the ease and success of the operation. * * * After the gorget was in the bladder he introduced his finger, and endeavoured to feel the situation of the stone, which, if found, is a great advantage in the direction of the forceps to lay hold of it. He never used any other than straight forceps, and it will be found more easy to extract a stone whole, by rather large forceps, than with flat or small ones." (p. 409-11.) Bromfield (b) describes very fully his mode of operating with the knife, and though not following Cheselden's method, distinctly shows that even he occasion- ally cut as Cheselden did, and as is stated by Douglas. " I begin my incision of the external integuments," says he, "about half an inch below the commissure of the ossa pubis, on the left side of the raphe, and pursue it by a quick stroke, obliquely outwards and downwards between the anus and obtuse process of the ischium, ending somewhat lower than the basis of that process. As soon as the integuments are (a) On Lithotomy; in Med.-Chir. Trans., (b) Chirurgical Observations and Cases, vol. xi. 1820. vol. ii. London, 1772. 8vo. 318 CUTTING FOR THE STONE | thus divided, I introduce the fore and middle fingers of my left hand : with the last I keep back the lip of the wound next the raphe, and with the index press down the rectum. I then make a second incision, almost in the same direction with the first, but rather nearer to the raphe and anus, and sufficiently deep to divide the trans- versalis penis, and as much of the levator ani and ligamentous membrane as will make the prostate gland perceptible by my finger; I then, with the index of my left hand, feel for the sulcus of the staff, which serves as a conductor to my knife for opening the membranous part of the urethra, and afterwards for dividing part of the prostate; the rectum is likewise by my fingers kept out of the way of the knife in the next part of the operation, which I effect in the following manner. Hitherto I hold the blade of my knife like a pen, between the forefinger and thumb, and resting on the middle finger of my right hand, with the back of the blade uppermost, but now I take it between the forefinger and thumb of my right hand, with the handle towards the palm of my hand on the inside, the back of the blade facing the inside of the index of the right hand : I then turn the back of this hand that holds the knife downwards, and convey the knife to the membranous part of the urethra, by gliding the under fingers of my right hand on the index of my left hand, which serves as a conductor of the knife to the gland ; as soon as I perceive that, I feel for the groove of the staff with the index of my left hand, with which I convey the convex edge of the knife into the membranous part of the urethra, as much laterally as is possible, and as nigh to the prostate. When I am clearly in the sulcus of the staff, I turn the back of my knife as much downwards as I can, to avoid wounding the rectum, as I then push the blade of the knife along the groove of the staff into the body of the gland, sliding the knife on the convexity of its edge, till it has divided nearly half the length of that gland; and if I wish to cut a little more of it, I incline the handle of my knife a little downwards, and towards the left ischium. The point of the knife will then drop into the groove of the staff, and by drawing the knife in this situation towards me, I shall certainly make good the wound of the prostate, so as near two- thirds of it may be divided in the operation. This last stroke of my knife is what is generally called "cutting from within outwards." I then introduce the beak of the common gorgeret, &c." (p. 229-32.) " The next step of the operation," says Brodie, " is the continuance of the incision along the posterior part of the urethra, and the dilatation of the neck of the bladder. Some recommend this to be accomplished by means of the common scalpel, with which you have made the external incisions; the point being steadily introduced along the groove of the staff, with the edge turned outwards, so as to divide the left side of the prostate. This was Cheselden's mode of operating.—[Not his last mode of operating certainly, as I have shown from his own words.—j. f. s.]—After having incised the prostate and neck of the bladder, Cheselden introduced the blunt gorget, so as to dilate the wound still further, answering at the same time the pur- pose of a conductor for the forceps; and, as far as I can learn, this method was fol- lowed generally by the English Surgeons up to the time of Sir Cjesar Hawkins," who "caused one side of the gorget to be ground to a sharp edge, and thus con- verted the blunt into a cutting gorget. * * * I cannot but think that there are some considerable objections to it (the cutting gorget.) The incision is made as it is being thrust into the bladder. In consequence of the thick wedge-like form of the instrument, the prostate, and especially a hard and enlarged prostate, offers to it considerable resistance. A certain quantity of force is_ necessary for its introduction; and if that force be not well applied, the beak may slip out of the groove of the staff into the space between the bladder and the rectum, an accident which is too surely followed by the death of the patient. * * * Although I have very frequently used the cutting gorget, I generally make the incision of the prostate with the knife," of which "the blade is broad enough to divide a considerable portion of the prostate as it enters the bladder, without its being necessary to increase the size of the incision by cutting laterally afterwards^ and instead of a sharp point, it terminates in a beak, fitted to the groove of the staff. In ordinary cases, a knife of this kind with a single cutting edge is sufficient, but in cases of very large calculi there are good reasons for dividing both sides of the prostate. There is no objection to this being done that I can discover, and for such cases I have been for some time in the habit of using a double-edged knife with a beak projecting from its centre. Having made the open- ing into the membranous part of the urethra; you are to insert the beak of the beaked knife into the groove of the staff, you then take the handle of'the staff into the left LATERAL OPERATION WITH THE KNIFE (LANGENBECK's.) 319 hand, depressing it at the same time. You depress your right hand also, so that the handle of the knife, which you hold in it, lies in the lower part of the external wound. You are now to push the knife along the groove of the staff into the blad- der, with its cutting edge inclined outwards, and a little downwards towards the ramus of the ischium, if you use a single-edged knife; but holding it horizontally, if you use one with a double edge. Let this be done slowly and cautiously, taking care that you do not lose the feeling of the beak sliding over the smooth surface of the staff for a single instant. Generally, as the knife enters the bladder, a few drops of urine escape, but never any large'quantity. This being accomplished, you are to withdraw the knife along the groove of the staff in the same line in which you intro- duced it. Never cut with it laterally, except you find it afterwards absolutely necessary to do so on account of the large size of the stone; for in cutting laterally, you will find it difficult to measure exactly the extent of your incision; and you may endanger your patient's life in consequence of your dividing the parts beyond the boundaries of the prostate. The next step of the operation is to introduce your finger, directed by'the staff, into the bladder, so that you may feel the parts which are divided, and determine whether the incision is properly made. If you operate on a child, or on a young and thin person, you may then at once introduce the forceps into the bladder. But if you operate on a full-grown person, and especially on one having a deep perinaeum, it will be prudent for you first to introduce the blunt gorget previously to using the forceps. * * * The gorget is intended to answer the pur- pose of a director for the forceps. But it answers another purpose also; it is a dilator of the wound—the knife divides only a portion of the prostate. The gorget splits the remainder as far as its breadth allows it to do so. Do not for an instant suppose that this is any rude or violent proceeding. It is far otherwise. The incision of the prostate having been begun by the knife, the extension of it by means of the blunt gorget is accomplished with the greatest ease. * * * You will ask why not make such a division of the parts by cutting laterally with the knife? Why prefer the dilatation of the wound by the blunt gorget? My answer is, that the separation of the parts with the latter instrument causes no haemorrhage ; and that it ceases as soon as it reaches the margin of the prostate; that is, as soon as it reaches the condensed cellular membrane, which forms what may be called its capsule." (p. 111-15.)] 2081. Langenbeck's knife {a) is specially distinguished by its point having a cover or guard, by means of which he passes it more readily and safely along the groove of the staff. It is used in the following manner:—When the membranous part of the urethra is laid bare; the nail of the left forefinger is placed in the groove of the staff, and directed by it, the point of the lithotome perforates, the parts still covering the staff; the right hand holding the stem of the lithotome, inclines it towards the right thigh, so that its point forms a right angle with the beak of the staff, the handle of wThich is held inclined towards the right groin, and with its outer edge a little downwards. The point of the knife is now carried a little forwards in the groove of the staff, for the purpose of en- larging the opening, and moved up and down in the groove, in order to open it satisfactorily. The hand of the assistant, and with it the handle of the staff, is then grasped with the left hand and raised so as to bring its concavity against the pubic arch : whilst this is doing the point cover is pushed forwards, the handle of the lithotome being firmly pressed against the palm of the hand by the ring, middle, and little fingers, the point of the forefinger carried from the back to the side, and the thumb on the back of the instrument, so that the latter lies fixed behind the button of the point cover, and, as it is straightened, thrusts the cover (a) Ueber eine einfache und sichere Methode des Steinschniites. Wurzb., 1802. His alteration of the Lithotome is found intheNeue Bibliothek fur die Chirurgie und Ophthal- mologic, vol. i. p. 429, f. 1. 320 CUTTING FOR THE STONE J forwards; the knife is then moved up and down to ascertain that it is actually in the groove of the staff. The lithotome then, with its edge towards the extremity of the cut in the skin, is thrust along the staff to its blind extremity, in doing which the point of the lithotome is first a little sunk and the handle raised, till it has passed beyond the curved part of the staff, when the handle is sunk and the point a little raised. The knife is withdrawn in the same direction. [Thomas Blizard, who was a very able operator, after opening the groove of the staff in the usual way, divided the prostate gland, laterally, by means of a narrow- bladed knife, about four inches long, and having a beak inclined at an angle towards the right side of the blade. (lam informed by his nephew Stanley, that he never lost a patient from bleeding, after this operation.) Astley Cooper, #1so, for a time used a long-beaked knife, but with the beak projected directly forward; the greater number of operations, however, which I saw him perform were done with the single- cutting gorget. He was, however, as Tyrrell observes, " fond of variety," and I have seen him operate with both single and double cutting and blunt gorgets, as well as with the knife. Tyrrell always used the straight-beaked knife for dividing the prostate gland. He was a very able and successful lithotomist, and thus describes his operation (a): "The staff is first introduced, and. should well fill the urethra; the larger it is the better, as you have the advantage of a deeper groove. The staff is then firmly held by an assistant, and the bulb of the penis is made to project a very little towards the left side. I now take the double-edged scalpel, make an incision through the inte- guments and fascia of the perinaeum on the left side of the raphe, commencing at the point just beneath the lower edge of the symphysis, at the place where the urethra begins to curve under the arch of the pubes, and continue it downwards and outwards to opposite the middle of the anus, between it and the tuberosity of the ischium. If you begin above the place just mentioned, it cannot be of any service in extracting the stone. I next make an incision into the groove of the staff, as near as possible to its median line, because I think the danger of haemorrhage from the transverse artery of the perinaeum or any other artery is less in proportion to the distance you are from its origin. As soon as I have laid open the urethra and carried the knife into the groove, I introduce the nail of the forefinger of my left hand and satisfy myself that the knife is properly within the groove, although you may feel pretty confident of it by the sensation produced in rubbing the knife in the staff. Then incline the edge of the knife a little outwards, and carry it on nearly to the prostate gland, then I carry it down deeply into the perinaeum, in the direction of the first incision, to divide the deep muscles there as I withdraw the knife. I then lay aside the scalpel, and take Astley Cooper's long straight knife in my right hand, take hold of the staff firmly with my left, and then introduce the beak of the knife fairly within the groove, keep it well against the staff, and carry it onwards, following the curve of the staff, into the bladder. The knife having entered the bladder, I give the staff to an assistant to hold steadily in the same position, and introduce my finger on the surface of the rectum, under the point of the knife, which I can then feel in the bladder, and divide the prostate, as I withdraw the knife, in the direction of the former incision, letting its probe point rest on my finger, which is at this time pro- tecting the rectum from injury. If I operate on a child, where the perinaeum is shal- low, i introduce my finger into the bladder and feel the stone, and then withdraw the staff and introduce the forceps on the finger. But if the perinaeum is deep, I introduce the forceps with the blades a little x>pen, and glide one blade along the groove of the staff, upon which it very readily finds its way into the bladder, and rests upon the stone, which I then grasp, by deliberately opening the blades of the forceps, and cautiously withdraw it." (pp. 637, 38.) To this account of Tyrrel's mode of operating I may add, that in.introducing and withdrawing the beaked knife, he did not hold the blade vertical, but with its sides inclining a little upwards and downwards, so that the edge was turned somewhat outwards, and the knife seemed to leave the wound after dividing the prostate almost flat.—j. f. s.] (a) Clinical Lectures on Stone in the Bladder; in Lancet, 1823-24, vol. ii. LATERAL OPERATION WITH THE CUTTING GORGET. 321 2082. The cut having been made in one of these ways, the finger is passed through the wound into the bladder, the staff removed, and, if the cut be sufficiently large, the forceps are introduced upon the finger, for the purpose of drawing forth the stone without much bruising and tearing of the edges of the wound; but if the cut be too small, it must be enlarged, carefully and slowly, with the finger, the forceps, or some special dilator, or with a button-ended bistoury, according to the direction of the outer wound. 2083. This mode of operating is the most simple of all; the operator does not depend on the mechanism of his instrument, but can modify its direction and efficiency at his pleasure. It is dangerous in unpractised hands, which, however, is also the case with every operation. The entrance of the knife into the groove of the staff may be difficult; it may slip from it, and the rectum and bladder may be wounded. Langen- beck's lithotome allows an easy and safe introduction into the groove of the staff. 2084. The cut into the neck of the bladder and the prostate gland^ith a particular instrument, from without inwards. To this belongs the use of the cutting gorget, and of Le Cat's bistouri cache. 2085. In using the cutting gorget, the nail of the left forefinger, after the membranous part is laid bare by the external cut, is introduced into the groove of the staff, and the membranous part of the urethra laid open to some extent by the bistoury carried upon it. The beak of the gorget is now entered into the groove of the staff thus opened, upon the finger- nail still remaining there, the handle of the staff gfasped with the left hand, and, after moving the gorget several times up and down, to ascer- tain that its beak is certainly in the groove, the gorget is pushed forward to the blunt end of the staff, the staff removed, and the forceps intro- duced. The cutting gorget, invented by Hawkins (a), in 1753, has undergone various modifications of which those by Desault (b), Cline (c), Astley Cooper (d), Scarpa (e), and Graefe (/) are considered the best. [Although Sharp (g) states, that Cheselden's lateral operation "is now (1751) the practice of most English operators," (p. 99,) yet it appears not to have been pursued for any great length of time, and perhaps, not so largely as Sharp would seem to infer; as if it were practised by others with any thing like similar success to that of Cheselden himself, it would be scarcely probable that Serjeant Hawkins should have set about improving the bluntgorget, by giving one of its sides a cutting edge, which he did between 1751 and 1754, for, "after having mentioned the objec- tions to the continued incision of the urethra, and prostate gland" in the old way, or with the apparatus major, Sharp (A) says:—"I shall observe, that Mr. Serjeant (a) A. F. Pallas, De variis Calculum (c) Erlich's Chirurg. Beobacht.j vol. i. p. secandi methodis. Ludg. Batav., 1754.—A. 227, pi. iii. f. 2, 3. Louis et 1 f auuer, Dissert, de Methode Haw- (dt) Savigny, Engravings, &C*, pi. vi. fig. 4. kinsiani in calculosorum scctione prasstasitiai (e) Mem. de l'Institut, vol. ii; p. 1.—Erin- Paris, 1770. nerungen iiber Hawkins sbbneiddendes (b) Abhandlung iiber der S'einschnitt Gorgeret zur Ausziehung des Blasensteines; nach der verbesserten HAWKixs'schen Me- in Salzb. Med.-Chirurg. <5eitung, vo\t j_ p_ thode; iu Chirurg. Nachlass, vol. ii. part iv; 31.—Ollivier, above cited, p; 1. pi. 1. p. 180.—Hausmann, Beurtheilung der Haw- (/) Bernsteines Prakt. Handbuch fQr KiNs'schen Methode der Blasenstein zu Wundarzte, vol. iii. p. 98. Fifth Edition. operiren. Braunschweig, 1782.—Loder, Leipzig. Bemerkungen iiber Hawkins'Methode; in (g) Treatise bri the Operations of Surgery. this Journal, vol. ii. p. 348. London, 1751. Fourth Edition. (h) Critical Enquiry into the present State Of Surgery; London, 1754. Third Edition Vol. hi.—28 322 CUTTING FOR THE STONE J Hawkins seems to have fallen on an ingenious contrivance, not only for removing them, but also giving the last hand towards perfecting the lateral operation.— [Though he should more correctly have said, altering the old mode of dividing the prostate with the blunt gorget, by dividing it with a cutting gorget, which was very different from Cheselden's operation.—j. f. s.]—This he effects by making his gorget to cut on the right side, so that when it is introduced upon the staff, and pushed on into the bladder, it necessarily makes an incision on the left side of the urethra and prostate gland." (pp. 212, 13.) As Hawkins's gorget still retained the form of the blunt gorget, except as to its cutting edge, it could not divide the prostate laterally, but upwards and outwards: or, as Scarpa observes, "not laterally, but rather at its upper part, towards the summit of the ramus of the ischium, and the arch of the pubes ; an opening of all others, in the perinaeum, the most confined, and presenting the greatest impediment to the passage of the stone from the bladder" (p. 13;) so that the prostate was really not divided as in Cheselden's operation. Hawkins's gorget, which was pretty much like Hildanus's conductor or blunt gorget, with the beak in the middle, had a cutting edge about two-thirds of its length; but Else (a) observed, that "it should not cut the whole length of the instrument, as it will then do much mischief by wounding the internal pudendal artery, which is pretty large, and cannot be easily secured, therefore the gorget should not cut more than half an inch in length." Whether this restriction of the length of the cutting edge originated with him, or with Benjamin Bell I cannot positively state, as the copy of Else's Lectures I have is without date : but I should be inclined to think it did, or it is probable he would have mentioned the in other respects variation of shape which Bell's gorget has. In this latter instrument, the shaft is much narrowed, and deep to within an inch of the beak, at which part it suddenly sweeps out on the right side like a lip, and thence cuts with a sharp rounded edge to the beak. A very slight inspection of either of these gorgets will show, that they cannot divide the side or thicker part of the prostate gland, but that they must cut through its upper part, making as Scarpa observes, "an opening, of all others in the peri- naeum the most confined, and presenting the greatest impediment to the passage of the stone from, the bladder." (p. 13.) To remedy this objection, the elder Clink made a most important change in the form of the gorget. Instead of the beak being, as previously, in, or nearly in the middle of the end of the instrument, which was rounded, he placed the beak on the left side, lengthening that side a third beyond the right side, by a flat horizontal plate beyond the concavity of the gorget. In this way a straight diagonal edge was formed, from the short right to the long left side of the instrument; this diagonal was made a cutting edge, and at its extremity pro- jected the beak about a quarter of an inch, flattened on the sides, and reaching a little above and a little below the cutting edge. The extent of the wound made by this instrument depended upon the width of the shaft of the gorget, which was equally wide and moderately deep, from the hind part of the cutting edge up to the handle. The width of the shaft varied from half an inch to an inch in different sized gorgets ; for children, the former was usually employed; in adults, generally one of three-quarters wide, and when the prostate was large, that of an inch. Such width was found by experience sufficiently ample for the division of the prostate, but not so as to cut into the cellular tissue surrounding that gland. With this in- strument I witnessed my highly valued master, the younger Cline, operate twenty- six times with the loss of three cases, one of which an elderly man, sunk within a few hours without any assignable or discoverable cause beyond the shock of the operation, and another, whose stone was triple phosphate, died a few days after, and was found to have the bladder, now in the Museum at St. Thomas's, much thickened, and its whole interior beset with fungosities. With the same instrument my friend Green cut about forty (b) cases successively, without losing a case. Sufficient proof, it must be admitted, that the cutting gorget is not the dangerous instrument, either as to its immediate or deferred results, which it has been so much the fashion to describe it. Scarpa objected to Hawkins's gorget, on the grounds already mentioned; and thought that the alterations of it by Bell, Desault and Cline, rendered it "an instrument, of all others, least adapted to the performance of the lateral operation" (d) MS. Lectures on Surgery. (b) Lancet, 1827, 28, vol. i. p. 61. THE LATERAL OPERATION WITH THE CUTTING GORGET. 323 (p. 14;) and therefore made an alteration of his own, which diminishing the general width of the instrument, still kept the two-thirds of the edge nearest the point cut- ting, as in Hawkins's instrument, but widening the middle third to the extent of three lines, in a somewhat elliptical form. His instrument has not, however, found many admirers in this country. Astley Cooper at first used a gorget with a central beak, "and cutting upon both edges, but he thought it occasioned too much bleeding, and divided more than was absolutely necessary for the removal of the stone." He therefore gave it up, and operated sometimes with Cline's gorget, and sometimes with his own knife; but I think I saw him more frequently use the former in his hospital practice.—j.. f. s. The directions given by Chelius for the use of the cutting gorget are not satis- factory, for more is requisite than to introduce its beak into the staff, and push it forward. Sueh, however, is the too common method of using the instrument, and hence arises the difficulty and danger with which, in the bands of inattentive per- sons, it is beset. It will be convenient here first to mention the directions given by Astley Cooper, for opening the membranous part of the urethra, which are those commonly adopted in the operation with the cutting gorget., " The scrotum being elevated, the incision is begun opposite the under part of the arch, of the pubes, and is continued on the left side of the raphe, along the perinaeumy as far as midway between the tuberosity of the ischium and the anus. The first incision should divide the skin, &c, and expose the accceleraior urinx; the second should be carried between the left crus penis and the bulb, the latter being pressed towards the right side by the forefinger of the surgeon's left hand. A part of the accelerator,• urinae is divided, and the transversus perinaei should be freely cut, as. it forms, a great impediment to the extraction of the stone, if undivided. The next incision should he made into the groove of the staff, by cutting into the membranous portion of the urethra,-, for this purpose the knife must be directed upwards, (that is, its point raised towards the. hand,le of the staff, —j. f. s.,) and not horizontally, otherwise the rectum is endangered. The opening made to expose the groove of the staff should be an inch in length." (pp. 241*, 50.) The membranous part of the urethra having been opened by the third cut, and well opened, by moving the point of the knife up and down so as to have it perfectly bare, the left forefinger-nail should be pressed into it, immediately on the knife being removed, and there retained,. Using the nail as a guide, the beak of the gorget (Cline's with the single-cutting edge) is entered upon it into the groove, and the finger withdrawn. The surgeon then moves the beak of the gorget twice or thrice up and down in the groove of the staff, to assure himself that the beak i§ free, and not entangled witb any cellular tissue, by which, in. his further proceedings it might be jerked out of the groove. The body of the gorget should be held hori- zontal, and its cutting edge inclined a little downwards, and outwards.. The operator now, with his left hand, takes the handle of the staff from the assistant, and brings it down till it form an obtuse angle with the perinaeum—in short, till the staff, if it were straight throughout and thrust onwards, would pierce through the umbilicus, its direction corresponding to the axis of the pelvis, which Green con- siders a most important part of the operation, as it ensures the proper course of the gorget. At the same time that the handle of the staff is sunk, the gorget is pushed very gently forward, and without any violent pressjure, cutting its way through, and dividing the prostate laterally, it enters the bladder. The great point to be remem- bered is, the depression of the handle of the staff, so that that part of its groove, on which the beak of the gorget rests, face downwards towards the scrotum, and con- sequently when the gorget is slightly pressed forward it meets no obstruction, and runs gently on. If, however, the staff-handle be not depressed, the beak of the gorget drives directly against the staff, and cannot move forward, the staff-groove standing ,up like a wall against it, and the opposition is the greater the more force is used, till the operator unwittingly alters the position both of staff and gorget, depressing the handle of the former, and raising that of the latter, so that its-point dips, finds less resistance in the now oblique position of the groove of the staff, and then is pushed on into the bladder, if the operator have good luck, or slips out of it,, and passes between the bladder and rectum, or between the bladder and pubes, which may be expected, if he use mueh. force and have little discretion. I have seen also, in more than one or two instances, when the staff-handle has been little or insuffii. ciently depressed, so much force used, without getting the gorget to move-on, that 324 CUTTING FOR THE STONE ; the staff was bent, above its curve, and could only be withdrawn with difficulty.— J. F. S.] 2086. All the cutting gorgets have this objection, namely, that in pushing forward their beak in the groove of the staff, they often merely push forward the neck of the bladder, and do not cut through it; they require much greater force than any other instrument; the inner wound has not the same parallel direction as the outer; on account of the lateral direction of the inner cut, the pudic artery is mast liable to injury ; and if to avoid this, a more descending direction be given to the instru- ment, there is no protection against wounding the rectum. The intro- duction of the forceps upon the gorget is but a trifling advantage (a). [These objections to the cutting gorget are entirely groundless. No more force is requisite for introducing the gorget than for dividing the neck of the bladder and the prostate with the knife. The instrument neither requires force, nor is force em- ployed, if the operator k»ow how to use it; and, therefore, whatever mischief is done is the fault of the surgeon, and not of the instrument. In passing into the bladder, the cutting gorget must cut through its neck, and also the prostate gland. It cannot push it before it, so long as it remains in the groove of the staff, but if it slip from it, as is occasionally, though not often the case, even in the hands of an unskilful operator, without violence, the beak of the instrument more readily slips between the. bladder and rectum then drives on the neck of the bladder. But this cannot happen, except from carelessness, without force being employed to drive the gorget on, which is never required so long as the instrument takes its. proper course; and if the gorget will not enter without violence, the surgeon may feel pretty well assured, in nineteen cases out of twenty, that he is misusing the instrument, and that he will get into mischief. The difficulty in introducing the gorget, and the force occasionally seen expended on it, depends, as has been mentioned, on the operator forgetting to sink the handle of the staff, so as to place its groove in the line which the gorget has to travel; and, consequently, herams the beak of the gorget against the staff, which he continues to hold nearly upright, so that till he accidently alter the position of the staff, or, by dint of force, the beak of the gorget slips down the curve of the staff, it is impossible for the gorget to pass into the bladder, though easy enough for it to slip from the staff, and get between the bladder and rectum. The want of parallelism of the internal with the external wound is really of no consequence, even admitting that it be greater than in division of the neck of the bladder, and of the prostate, with the knife, of which I cannot allow it is. The division,, or rather wounding, of the pudic artery, by the introduction of the gorget, might be matter of more serious objection against the employment of that instrument, were it as frequent as Chelius and others imagine; but from my own observations of the practice of others, as well as my own, I believe it very much less frequent than generally supposed; and the free bleeding which occurs some- times in the operation, either with the gorget or knife, for I have seen it as great with the use of one as of the other instrument, depends, I believe, usually on division or wounding the artery of the bulb, just after it comes off from the pudic artery, and not from injuring the pudic artery itself. The use of the gorget, as a ready channel for the introduction of the forceps, is, as Chelius observes, of but little im- portance.—j. f. s,] 2087. Le Cat's method, which, in recent times, has been especially modified and employed by Panola, is characterized by the prostate gland being in part only divided, and the enlargement of the wound being effected by a, peculiar dilator. According, to Pajola, the patient should be laid with his trunk a little obliquely; the staff, when introduced, is to be held by an assistant, with its handle so inclined towards the right groin, that its curved part should (a) Textc-H, C.,( Ueber die Ursache des Nichtauffindens der Blaseiisteine, nach gernach- ter Operation der Lithotomie, p. 22. Wurzburg, 1816.—Zang, OperationeD, vol. iii. pt u\p. 1.77., LATERAL OPERATION WITH COME's LITHOTOME. 32£> rest between the left side of the raphe and the ascending branch- of the left haunch bone. The external cut is made, as regards its size and direction, in correspondence to the prescribed directions, {par. 2078^) with the urethrotome, which is held like a writing-pen, with its groove facing towards the patient's left side. When the membranous part of the urethra is laid1 bare^ the nail of the left forefinger is passed into the groove of the staff, the bulb pressed aside, the urethrotome thrust into the membranous part close behind the bulb, and carried carefully along the groove of the staff, so as to divide the membranous part to the extent of from four to five lines. The operator now keeps the point of the urethrotome against the staff, brings its handle horizontal, and takes hold of it with his left hand in such way that the thumb is on the upper edge and the fore, middle, and ring fingers are upon the under edge of the handle. The operator-now grasps the cystotome with his right hand, and placing his middle finger in its ring, his third and fourth fingers on the under, his thumb on the upper surface of its handle, and the forefinger on the sheath of its blade* enters its beak into the groove of the urethrotome, and upon it into that of the staff, and then takes away the urethrotome. When the operator ascertains by the sensation which the contact and rubbing together of the two metallic bodies affords, that the beak of the cystotome is actually in the groove of the staff, otherwise the cystotome must be withdrawn, the membranous part at once opened and the instrument introduced as before, he- grasps, with his-own left hand!, the handle of the staff, together with his assistant's hand, carries it in a: direction corresponding to the white line, raises it beneath the arch of the pubes, so that it forms a right angle with the trunk, and pushes the cystotome, the handle of which he sinlcs a little, along the groove of the staff, up to its.blunt extremity. After the cystotome is withdrawn, the operator carries the point of his left forefinger upon, the staff and into the opening in the bladder; the staff is then withdrawn., and'a blnnt gorget, previously oiled, with its concavity upwards, is introduced upon the sensible surface of the left forefinger, which serves as a guide. The dilator, with its-front blades-closed, is.now* introduced,upon the gorget, and after the withdrawal of the gorget, the wound in.the prostate gland is gradually enlarged by bringing'together the hind branches of the dilator to such an extent as the size of the stone seems to require. For the further description, of this operation, the following Writers, are referred!' to:— Le Cat, above cited. Kast, (praeside C.Siebold,) Histor^i Lithotomia; in eodem homine bis facta?*. Wirceburg, 1778. Hartenkeil, above cited; Loder, Programma Lithotomiae LeCatian^ emendatae Descriptio. Jenae, 1785.-, Koelpin, A., De Calculi Vesicae sectione laterali inprimis Le Catiana; in Opus- ' cula Chirurgica, vol. i. Hafnia;,.,1799. Rudtorffer, F. X., Abhandlung iiber die Operation des Blasensteines, nach,, Pajola's Methode. Leipzig, 1808; with five plates. 208S. This operation has-partly the same objection as the cutting gorget, that' the parts are easily pushed before.it, and not always cut through to the required extent; and that the enlargement of the insuffi- cient cut with the dilator not unfrequently causes great bruising, and its, consequent symptoms, especially a permanent weakness of the neck of 28* 326 CUTTING FOR THE STONE J the bladder and the like. Experiments upon the dead body have satis- fied me that the use of the dilator does not effect a simple enlargement, but if the extension be great, an increase of the wound by tearing. In other respects this operation is more complicated than all the other modes; it is, however, employed with considerable success. 2089. The Cut into the Jfeck of the Bladder and the prostate, with a particular instrument, from within outwards. To this belongs Frere Come's method with the concealed lithotome {lithotome cache.) When the outer cut has been made and the membranous part is opened, the concealed lithotome is entered into the groove of the staff upon the nail of the left fore-finger, which has been previously introduced into it. The operator with his left hand grasps the handle of the staff, raises it under the arch of the pubes, satisfies himself that the lithotome is in the groove, by moving it up and down, and then pushes it on in the direction of the staff, to its extremity. The staff is now withdrawn, after having been passed a little farther into the bladder, to disengage the point of the lithotome, with which it must be attempted to ascertain the size of the stone, and then the instrument is gauged at a higher or lower number, in accordance with the size of the required cut. The lithotome is now held with the left thumb and fore-finger on its lock, is raised under the pubis arch,, and whilst the handle is grasped with the right hand, and the lever pressed down with the third and fourth fingers upon the handle, the blade is drawn out horizontally, and inclined towards the lower angle of the wound. The following writers may be referred to on this operation:- Journal des Seavans, 1748, Juki. Frere Come, Recueil des pieces impartiaJes sur l'Operation de la Taille faite par Ite Lithotome cache. Paris, 1735=. . -----„,,. L,.,; Additions a la suite de Recueil de toutes les pieces qui ont ete pub- lliees au sujet du Lithotome cache. Paris. De Preval, Ergo sealpello vagina recondite cystotome lateralis perfectior. Paris, 1754. Cambron, Lettre sur la Lithotome, pour prouver la superiorite du Lithotome cache. Paris, 1760. Nahuys„ Parallele de la Taille laterale de M. Le Cat avec celle du Lithotome eache. Amsterd., 1766. Chastanet, Lettres sur la Lithotomie, pour prouver la superiorite du Lithotome eache pour l'Operation de la Taille sur tous les autres instrumens. Paris, 1768. Sabatier, Remarques sur l'Operation de la Taille avec le Lithotome cache, et sur le Jugement que PAcademie de Chirurgie a porte de cette operation, dans le troisieme Yolurae de ses Memoires,; in Mem. de l'Institut National de Franee, vol. iii. p. 341. 2090. The disadvantages objected to the concealed lithotome are, wounding the inner wall of the bladder when its blade is gauged at the higher numbers; the great danger of wounding the rectum or the pubic artery if its blade be not immediately directed towards the ischial tube- rosity; and the difficulty of finding the aperture in the bladder, when the staff has been withdrawn before the cut is made (a). It has been attempted to do away with many of these objections, by shortening and blunting the blade, so that after the lithotome has been introduced into the blad- der the staff should net be withdrawn, but that, without its point leaving (a) Memoires de l'Acaderaie de Chirurgie, vol. iii. p. 628.—Scarpa, Dupuytren^Textob,, above eked. THE BILATERAL SECTION. 327 the staff, the lithotome might be drawn out of the bladder, or that the instrument should be furnished with a small gorget, or with a sheath to its blade (a). It must be remembered, however, that with very unruly patients this instrument can be used more safely than any other, and is always to be considered as one of the most preferable. Boyer (b), who prefers Frere Come's lithotome to any other, uses it in the fol- lowing way:—In adults and elderly persons he never gauges the instrument higher than No. 11, however large the stone maybe, and in general only up to No. 9. He prefers enlarging this cut if it be too small. In drawing out the instrument, instead of pressing the shaft up against the pubic arch, he presses its concave side on the branch of the right pubic bone, so that the blade is inclined almost directly outwards. When he is satisfied by the length of that part of the instrument which has been drawn out, and the cessation of resistance that the prostate and the neck of the blad- der are cut through, he allows the blade to return into its sheath, and withdraws the instrument closed, by which wounding the rectum and the pudic artery are avoided. The transverse direction of the inner wound is made correspondent with the outer by the introduction of the finger, and does nob prevent the entrance of the forceps. 2091. In the same way, as Chaussier and Beclard (par. 2062) had recommended cutting into the prostate and neck of the. bladder on both sides, as being the more correct interpretation of Celsus's text, did Dupuytren perform successfully and fully lay down this mode' of ope- rating, the bilateral section,,zs it is called, in the year 1824. The patient is placed and fastened in the usual way, and the staff held by an assistant vertically and corresponding to the raphe. The operator with a straight-pointed bistoury makes, at a distance of six or seven lines from the rectum, a transverse cut, the slight curve of which has its concavity downwards, and its middle over the raphe. The mem- branous part being laid bare, is opened, and the point of the bistoury introduced upon the nail of the left fore-finger into the groove of the staff, and carried some way along it. A peculiar lithotome is then en- tered into this opening, and pushed along the groove of the staff into the bladder. The neck of the bladder is divided, in withdrawing this instrument, by knives; which project on both sides, in the direction of the external wound. A gorget is then introduced, and upon it the forceps. Dupuytren's lithotome is similar to that proposed by Fleurant for operating on women for the stone; the two blades may be separated to a distance of eighteen lines. Charriere's improvement consists in the blades projecting obliquely down- wards. La Serre's alteration which is inefficient, consists in their acting first in the horizontal, and then in an oblique direction. Astley Cooper cut through the neck of the bladder on both, sides with a double-edged gorget. Upon this subject the following works.may be consulted:— Ollivier, above cited, p.. 237. Archives Generales des de Medecine* vol. v. p. 159. 1824. Repertoire Generale d'Anatomie et de Physiologie Pathologrques, vol. i. p. 240. Lecons Orales des de Clinique Chirurgicale, vol. ii. p. 381. Dupuytren, sur une Maniere Nouve'le de pratiquer l'Operation de la Pierre; ter- mine et publ. par Sanson et? Begin. Paris, 1836. [Lectures on Lithotomy, by Alex. Stevens, M. D., New York, 1838.— G. W. N.] 2092. Beglard altered his mode of performing the sectio bilaterali* (a) Beck, R., Ueber den Seitenschnitt mit (6) Traite des Maladies Chirurgicales, vol.. dem Stromeyer's chen doppeltgedeckten, ix. p. 391, Sfeinmesser. Carls., u. Freib., 1844. 328 CUTTING FOR THE STONE ; from that which he first advised, and proceeded in the following manner: Leaving the staff, which had been first introduced, alone, so as not to disturb the position of the parts, he made a cut through the coverings, as in the lateral operation, with a knife similar to that of Dubois; then opened the membranous part upon the left side and behind the bulb, and passed the knife nearly transversely, with its edge directed to the left, into the bladder, and enlarged the opening in drawing back the knife. At this point of the operation, he raised his hand, and gave the blade of the bistoury a direction parallel to the axis of the prostate, in order to avoid injuring the seminal vesicles and the base of the bladder with the point. If the stone eould not be drawn out through this opening, he enlarged it with the button-ended bistoury; and if this did'not answer, he made a second cut transversely to the right side into the neck of the bladder and body of the prostate. Senn (a) proceeded in the same way, exeept that he directed the first cut into the neck of the bladder, more obliquely downwards, as in the common lateral operation. The external tegument need not be cut into in the second transverse cut, as it is capable of great extension. Le Dran (b) had already proceeded in a similar way; after cutting into the neck of the bladder, he passed his forefinger into the neck and upon it a small bistoury, and then made upon the right side a cut similar to that on the left. Vidal de Cassis (c) has proposed cutting into the neck of the bladder in four directions. And Colombat has recommended an instrument, (lithotome quadruple,) in which two blades project upwards and- outwards, and two downwards and out- wards (d). 2093. The advantage of the bilateral section is, that it affords a cut of very large extent for the removal of a large stone ; without danger of wounding the pudic artery; and the rectum may be avoided, notwithstand- ing the large size of the cut. In regard to Dupuytren's semicircular ex- ternal cut, it may be remarked, that the transverse artery indeed may be avoided ; but that this cutis difficult for a less experienced operator, and a> slight variation from the prescribed mode causes that vessel to be wounded. The bulb is. also easily wounded, especially in old persons, in whom it is large, and juts back so much that it is not easily pressed down ; and if the knife be sunk deeper to avoid it, there is danger of wounding the rectum. Both, however, may, according to Senn, be more certainly avoided, if the membranous part be divided, not lengthways, but transversely. Beclard thought it a particular advantage of this ope- ration, that the edges of the wound lie close together, and that the cure follows more quickly (e). Souberbielle (f) consider that the double cut should' be so large, that the extraction of the stone should entirely separate the middle from, the other parts, of the prostate. 2094. One of the most important circumstances, which has the great- est influence in deciding on the several modes of performing the lateral operation for the stone, is. the variety of opinions- as to the room which (a) Dissert. Recherehessur les differentes chives generales.de Medecine, vol. viii. p. Methodes de Taille soupubienne. Paris, 139, 309, 310. 1825. (e) Ollivier, above cited, p. 244—Roter. (6) Suite des differente&.manieres de faire Coli.ard; in Repertoire generate d'Anatomie ^Extraction de la Pierre. Paris, 1756. et de Physiologie, vol. i. p. 507. (c) Taillie quadrilaterale These. Paris, (/) Journal deMedecine,,vol..&vii. p. 416. ]£28.. 1822. (d) Ollivier, above cited, p. 238.—Ar- THE EXTRACTION. 329 the cut into the prostate and neck of the bladder can give, and which can be given with safety. Many make the cut so large that the stone can be withdrawn without stretching and bruising the parts; they divide, when the size of the stone needs it, the whole prostate, and continue the cut even into the body of the bladder; considering a clean cut less disadvan- tageous than the tearing and bruising by simple dilatation. Others fear large cuts, as if the whole prostate be divided into the bladder, infiltra- tion of urine, abscesses and gangrenous destruction of the cellular tissue between the bladder and rectum, weakness of the neck of the bladder, slow cure, and fistula, may ensue. It is most advisable to cut sufficiently deep into the prostate and neck of the bladder, without continuing the cut into the body of the bladder, and to enlarge the opening in a gentle and gradual manner with the finger or the forceps. This enlargement may be carried to such extent that very large stones may be withdrawn, and by this mode of enlarging the wound the objections do not apply which for the most part result from the great apparatus, as if the prostate and neck of the bladder be pro- perly cut into, the enlargement is made in a very different way. To Dubois' knife, with which I cut into the prostate and neck of the blad- der, as I introduce it, but especially in drawing it out, I give the prefer- ence above all the other modes of practice. If the cut do not correspond with the size of the stone, I enlarge it with the button-ended straight bistoury, which cuts only to the extent of an inch. [Scarpa, as already noticed, (p. 583,) has well pointed out the extent to which the prostate should be divided, and the capability of doing this, to a certain and de- finite extent, is the great advantage of the cutting gorget, which ean only divide the prostate equal to its own breadth. If the prostate be divided with the knife, the ex- tent of the division must depend entirely upon the operator, and is liable to vary con- siderably.—j. f. s.] Upon the matter just considered the following works may be also consulted :— Klein, Chirurgische Bemerkungen, p. 1. Stuttgart, 1801. Prak'tische Ansichten der bedeutendsten chirurg. Operationen; part ii. Stuttgart, 1816. Martineau, in Med-Chir. Trans., vol. xi. p. 402. 1820. Cooper, Samuel, Dictionary of Practical Surgery,—Art. Lithotomy, p. 889. Dupuytren, above cited, p. 17. Scarpa; in Ollivier, p. 1-40. Chelius, Ueber den Steinschnitt; in Heidelb, klinisch. Ann., vol. vi. part. iv. 2095. The extraction of the Stone is in general accompanied with great difficulty, and requires the more careful and skilful management, as upon the proper performance of this part of the operation depends principally its successful or unfavourable result. The left forefinger, and in very stout persons, a blunt gorget upon it, is passed into the opening of the neck of the bladder, and upon it the forceps (a), previously oiled, are carried in a rather oblique direction from below upwards into the bladder. The forceps are then gently turned about in various directions to find the stone, and when it is found, the handle-rings of the forceps are to be taken hold of with both hands, widely opened, and the forceps pushed farther into the bladder, or turned half round with a sweep, so as to bring the stone between their blades and to grasp it. When the separation of (a) On the Construction of the various kinds of Stone-Forceps, see Deschamps, above cited vol. iii. p. 200. 330 CUTTING FOR THE STONE \ the handles shows.thatthe stone is seized, the thumb and middle finger of the right hand are put into the rings of the forceps, or the instrument is grasped with the whole hand, but in either case the forefinger is kept be- tween its handles, partly to prevent breaking the stone, and partly to pre- vent the walls of the bladder catching in drawing out the forceps, which are to be turned round on their axis, so as to ascertain that the bladder has pot been laid hold of. The surfaces of the blades of the forceps are then directed towards the edges of the wound, the left hand placed on the joint, and with a continued gradually increasing pull, accompanied at the same time with waggling movements obliquely from above downwards, the forceps, together with the stone, are drawn out. If during the ex- traction the edge of the wound be stretched very tightly over the stone, it must be held back with the finger of the left hand. 2096. The obstacles which occur in grasping and drawing out the stone depend on its position and size, on the contraction of the wound of the bladder, on the stone being encysted or adherent, and on its breaking to pieces. 2097. If the stone lie low, it must be attempted by the forefinger of the left hand, passed up the rectum, to carry it towards the forceps, or a pair of curved forceps may be used. If the stone be very high, or in the sides of the bladder, it must be tried to change its position with the finger, to thrust it down by pressure on the lower part of the belly, or curved forceps must be introduced ; and in using the latter, their handles must always be inclined downwards. 2098. If the stone be grasped in an unfavourable diameter, or too near the joint of the forceps, which is shown by the very great separation of their handles, or if the stone lie with its long diameter transversely within the blades, which is discovered by the slight separation of the handles, and the difficulties in attempting the extraction, the forceps must be opened a little, and with the finger, or with a bouton (a), it must be tried to give it a better position; or it must be dropped into the back of the base of the bladder, and seized afresh. If the wound be too small, though the diameter of the stone be favourable, it must be enlarged, as directed, (par. 2094,) to such an extent as to render the ex- traction possible, without much bruising and injury. If the stone he of such a size that even with the greatest possible enlargement of the wound it cannot be removed, nothing remains but either to break it to pieces with Earle's (b) stone-breakers; or if the stone be not too hard, the outer layers may be broken with a pair of common stone-forceps; or, what is still better, Heurteloup's percuteur may be used; or the bladder may be cut into above the pubes, which proceeding is always most proper when the stone is very hard. Under these circumstances, also, the extraction of the stone has been recommended to be made sub- sequently, {Steinschnitt in zwei Zeitraumen, Germ.; Taille en deux terns, Fr.,) when suppuration has commenced in the wound ; the extraction, however, is never thereby rendered easier, and this practice is in gene- ral to be rejected. Small stones may also lie so between the blades of the forceps, that the handles are not separated, and the operator (a) An instrument like the stilette of a catheter, with a ball at its extremity. (6) Med-Chir. Trans., vol. xi. p. 69. pi. iii. 18. THE EXTRACTION. 331 thinks he has not grasped the stone; in withdrawing and accidentally turning of the forceps, such stone may remain concealed within them, without the operator being aware of it, as I myself have observed. The gush of urine, after cutting into the neck of the bladder, may also throw out a little stone. Small stones can often be well seized with a pair of dressing-forceps, or with flat-bladed stone-forceps. Campana (a) considers the extraction of the stone more easy and less injurious, if it be grasped by its largest diameter. [If after the entrance of the gorget into the bladder, the urine do not immediately flow out, as it usually does, though less frequently when the internal wound is made with the knife only, it does not gush forth suddenly as soon as the forceps are intro-- duced; "not impelled," says Brodie, "by muscular exertion, but by its own gravity and the pressure of the viscera. Under these circumstances, when you in- troduce your finger into the bladder, " you find the muscular tunic relaxed, and the mucous membrane hanging in folds ; and in consequence they are not likely to be ruptured. In other instances, the patient voids his urine immediately after the ope- ration, or perhaps during the introduction of the staff. Here, the urine having been made to flow by the patient's own efforts, the muscular tunic is contracted; it offers a considerable resistance to the opening of the forceps, and is liable to be ruptured, if the blades are opened rudely and incautiously." (pp. 317, 18.) A case of this kind Brodie mentions, in which " the bladder (as he supposed) was in a contracted state, and the surgeon, in opening the forceps, observed a resistance, which suddenly gave way, as if a ligature had been broken." * * * On the third morning after the operation, he died, and on examination, it was "found that the mucous membrane and muscular tunic of the bladder had been ruptured to the extent of three quarters of an inch." (p. 304.) I have, very recently, in operating on a child of nineteen months, been inconvenienced by the violent contraction of the bladder which Brodie mentions, and to a degree of which I had no notion. I had operated with the cut- ting gorget, and introduced the forceps with perhaps a little more difficulty than usual, and immediately found the stone; but on attempting to open their blades, I found it impossible without using force, which was not justifiable. I passed the blades farther in, drew them back, gave them a quarter turn, each time endeavouring to open them, but in vain; they were as firmly closed as if they had been tied to- gether, and a momentary thought passed through my mind, that they might have escaped from the gorget, and slipped between the bladder and rectum ,• however, feel- ing the stone distinctly, again and again, I was convinced that could not be the case, and that the blades were fairly in the bladder. I continued making gentle attempts to open them, and full five minutes elapsed before they would move at all ; they then began slowly to open, and at last sufficiently toallow the stone to get between them, when it was extracted, though not before it had slipped once or twice, as I could only at first catch hold of the edge, the principal part of the stone seeming to have been lodged in a fold of the bladder, from which I could not disengage it. Now, had I violently attempted to open the forceps in this case, I should undoubtedly have torn the bladder, as in that mentioned by Brodie ; but using only gentle efforts, the bladder yielded slowly, and the operation was safely completed.— j. f. s.] 2099. When the stone is enclosed by a diseased contraction of the bladder, attempts must be made to free it by introducing the finger, or a pair of stone-forceps, the blades of which must be opened in different directions before the stone, so as to separate the walls of the bladder. For this purpose, forceps with several arms, capable of being applied singly have been proposed (b). If the stone' cannot in this way be grasped, its extraction must be given up, and the spasm attempted to be removed with antispasmodic remedies, fomentations, and the like. (a) von Graefe und von Walther's Journal, vol. v. p. 171. (b) Deschamps, above cited, vol. ii. pi. i. fig. 14, pi; vi. fig. 8, 9i 332 CUTTING FOR THE STONE J 2100. If the stone be encysted, the operator carries his forefinger to the stone, and endeavours, if the encystment be not considerable, to set it free. If this be not possible, on account of the opening of the cyst being very small, a narrow blunt-pointed bistoury, or a bistoury con- cealed in a sheath and $ little curved, must be passed in upon the left forefinger, and in its passage attempts must be made to lay open the cyst to such extent as may be necessary for setting the stone free, which if its position allow, may at the same time be raised by the introduction of an assistant's finger into the rectum. Stones which lodge in the ureter and project into the bladder must be loosened with the finger, carefully seized with the forceps, and attempted to be freed by gentle pulling; as every violent pull is extremely painful to the patient, and drawing the stone towards the neck of the bladder troublesome, however large the wound may be. If the stone lie in a hollow, formed by the protrusion of the lining mem- brane between the fibres of the bladder, it must be attempted to enlarge the opening of the communication by introducing a pair of small forceps, and then to draw out the stone. The difficulty in doing this will depend upon the nearness or distance of the stone from the wound. If the stone be covered with the inner coat of the bladder, in which case it has been thrust between the membranes at the orifice of the ureter, nothing can be done except proceeding as with a partially encysted stone, or it may be grasped with the forceps, and drawn out with careful movements. When a stone is covered with fungosities, the finger is to be carried between it and the wall of the bladder, their connexions separated, and the stone pulled out by moving it in different directions, and if the con- nexions be very firm, it must be attempted to loosen the remaining part by frequent injections, and by shaking the patient, and afterwards to ex- tract the stone (a). 2101. With a brittle and easily-breaking stone, it must be endea- voured, by the introduction of the forefinger between the handles of the forceps, to prevent them being too firmly closed, to avoid breaking the stone ; and for this purpose various apparatus, as forceps with a bag to catch the stone, and so on, were formerly proposed. When, however, the stone has been broken, the larger pieces must be removed with the forceps, the smaller with a scoop, and the little pieces by repeated in- jections, with warm water from a clyster-syringe, the pipe of which is to be passed into the bladder on the forefinger. Klein (b) advises that, in this case, as also when numerous little stones have been removed, the bladder should always be examined with the sound some days after, for the purpose of ascertaining that nothing remains behind. If the stone break when it has been brought into the outer wound, it must be pressed out by the left forefinger in the rectum.. 2102. When the operation is finished the perineum must be cleaned, the patient freed from the ligatures, and several turns of a bandage passed round above and below the knees, to keep the thighs together. He must be kept in bed$ lying on one or other side, or on his back, with the thighs drawn, up and the knees supported. A moist sponge is applied to the wound, and oiled silk or folded cloths laid to prevent the fouling of the bed by the urine: which flows out. (a) Klein ; in Loder's Journal; v6l. iv. p. 564. (b) Above cited, p. 380. BLEEDING. 333 2103. The accidents, besides those already mentioned, in the extrac- tion of the stone which may occur during the operation and require par- ticular treatment are, bleeding, injury or prolapse of the rectum, convul- sions, and fainting. 2104. Bleeding may happen from the superficial perinasal artery or its branches, from the transverse perinasal artery, from the inferior or from the internal hcemorrhoidal artery, from the internal pudic artery, from wounding the bulb of the penis, and from the posterior or inferior vesical arteries. The branches of the superficial perinseal artery can only produce an alarming bleeding in those cases where it is unnaturally large. The transverse perinseal artery lies so near the ramus ischii that it cannot easily be wounded, if the cut be made at the proper height (par. 2078.) The inferior heernorrhoidal artery is sometimes injured when it is further forwards than usual, or the cut is continued beyond the line from the anus to the ischial tuberosity. The branches of the internal hasmor- rhoidal artery spreading between the neck of the bladder and the rectum may bleed. The internal pudic is wounded when the cut is made too far to the side. The vesical arteries may be wounded if the prostate be complelety cut through, and the body of the bladder itself cut into. The bleeding from the superficial vessels of the perineum may be stanched by tying them ; but that from the deeper vessels requires cold applications, and if these be insufficient, compressipn must be made with a silver or elastic tube, open on both sides, and with a linen bag attached to its front part {canule a chemise.) The front end having been pushed into the bladder, lint is passed between the tube and the linen bag, till sufficient pressure is made on every part of the wound, and the other end of the tube is fastened externally with a T bandage. Erard (1), Dupuy- tren (2), and von Graefe (3), have recommended particular compres- sors for this purpose. The injury of the internal pudic artery may cause so considerable bleeding that the extraction of the stone must be deferred; pressure, in the way prescribed, will, however, always be successful in stanching the bleeding. It has been also advised to keep up pressure with the finger by relays of assistants, or to tie the artery by means of a particular kind of needle (a), or with Deschamp's- (6) artery-needle. According to my own experience, however, the continued and efficient application of cold is the best mode of stanching bleeding after cutting for the stone ; I have succeeded with it when pressure had been used in vain (c). (1) Erard's (d) compressor consists of a canula, at the vesical end of which are two wings, which jut against the inner wound, whilst a plate furnished with com- presses is pressed against the perinaeum with a screw. (2) Dupuytren's (e) compressor has two branches, flat on their inner, convex on their outer surface, and by their elasticity capable of separating from each other like the branches of common dissecting forceps. The branches are covered with leather and agaric, the latter upon their convex surface. The instrument is to be passed, closed, into the wound, the one branch put against the seat of the bleeding vessel, and then the branches allowed to open. If the bleeding stop, the instrument must {a) Zang, Operationen, vol. iii pi. ii. f. 5. (d) De l'Hemorrha?ie a. la suite de la (b) Bovkr, above cited, p. 435. Taille, &c. Paris, 1822. (c) Heidelberg klinish. Annalen vol. vi. (e) Memoire acheve etpubl. par Sanso.v et part iv. Begin, p. 50. Vol. hi.—29 334 CUTTING FOR THE STONE ; be left there; but if otherwise, its position must be altered till the bleeding vessel is fully compressed. (3) von Graefe's (a) compressor resembles Weiss's speculum, and consists of four branches, the outer surface of which is covered with agaric: it is introduced, closed, into the wound, and then the branches opened by a screw, so that the regular pressure is made on every part of the wound. Shaw (b) has described a case of fatal bleeding, in operating for the stone, from wounding the dorsal artery of the pern's, which was given off as a large branch from the hypogastric artery in the prostate gland, and was continued under the pubic arch to the pern's. He has found this variety of the artery frequent, as has also Tiede- mann (c) and Burns. [With regard to the loss of blood during the operation for the stone, Brodie says :—" I have sometimes heard it observed, when a patient has lost a good deal of blood at the time of the operation, that he has lost no more than it will do him good to lose." I have, however, great doubts whether even in the case of the strongest man, the losing much blood adds to his chance of recovery, and it is evident, that in the case of a person of originally weak constitution, or of one whose bodily powers are exhausted by his previous sufferings, or who labours under disease of the kid- neys, or other organs, ihe loss of a considerable quantity of blood in the operation, is likely to make all the difference between its success and failure." (p. 335.) As to the bleeding which occurs during the operation ; though free, it often ceases almost immediately after the patient is unbound, and the legs brought close together, and requires nothing further. But if it continue, and the patient become faint and pallid, it will be necessary to.put a stop to it, otherwise the bleeding will be fatal. Brodie mentions the case of an elderly man with an enlarged prostate and deep perinaeum, in whom " the blood seemed to proceed from the neigbourhood of the neck of the bladder, and what was remarkable, it was venous. He was foiled in all his attempts to restrain the haemorrhage, and the patient survived the operation only a few hours." (p. 335.) I have also known a case or two in which the bleeding was fatal: but such instances are rare. When the bleeding continues after the operation, the wound must be gently opened and carefully examined. If any vessel can be seen, it should be taken up and tied ; But if, as is more commonly the case, the transverse perinseal artery, or the artery of the bulb, which I believe is far more frequently the bleeding vessel than the pudic, which lies so protected by the ramus of the ischium, that it is scarcely possible to be injured with the gorget, though it may be cut through with the knife, be cut off close to its origin from the internal pudic, there is not room to apply a ligature around either of the former; and with regard to the pudic, it is next to impossible to get at it at all with a needle. In such cases the best and safest proceeding is to pass the finger into the wound, and press the artery steadily against the ramus ischii till the bleeding.cease. This will require to be continued for several hours, and will need a relay of assistants. • I have seen two cases so treated successfully. The first case was under my care during my dressership, and the pressure was kept up un- interruptedly for fourteen hours, and with very little inconvenience to the patient. Attempts had been made both to tie the vessel, and to cut it across, so that its ends might retract, as it was supposed to have been merely wounded, but they were quite fruitless. In the other case, fouror five hours were sufficient to put the patient in safety. Under these circumstances the surface of the wound generally sloughs, and the cure is retarded. Sometimes, the blood instead of escaping by the outer wound, flows back into the bladder, and forming a clot, prevents the passage of the urine either by the wound or by the urethra. I have known this happen in a few instances, without the bleeding however, being serious, or affecting the constitutional powers. If the patient do not pass water in the course of a few hours after the operation, if he become restless, and if there be fulness and uneasiness, or pain about the region of the bladder, it may be suspected, that blood has flowed into the bladder and clotted. It is then necessary to pass the finger gently through the wound into the bladder, and imme- diately this is done the urine escapes and clots of blood with it. Should the bladder (a) Journal von Graefe und von Walther, (6) London Med. and Physical Journal, vol. xxii. p. 65. vol. Iv. p. 2. 1826. (c) Tabulro Arteriarum, pi. xxx. f. 2. SECONDARY BLEEDING. 335 be found much distended with blood, it is well to wash it out gently with a syringe and warm water, which may be repeated once or twice at intervals, according to circumstances. Plugging the wound, or other of the appliances mentioned by Chelius, I do not think at all proper. Secondary bleeding, in rare cases, follows at an interval of several days after a patient has been cut for the stone. Brodie mentions one •if a child in the second week, which occurred under his own care, and*though the boy was excessively lower by the bleeding, he recovered. Also a case of Earle's, which bled on the seventh or eighth day, and was stopped " by introducing through the wound into the bladder, a tent composed of a quantity of lint wrapped round an elastic gum catheter." (p. 335.) The first case of this kind which I witnessed was under my care during my dressership in 1816, and had been operated on by the elder Travers. At the time of the operation much blood was lost, but it soon stanched. On the fourth day there was a sudden bleeding from the wound, to the amount of a pint and a half, which was stopped by pressure with the finger. On the following day the bleeding returned twice, and he lost another pint of blood ; pressure was again made for five hours; the bleeding was not repeated, and he recovered. A similar case occurred to Green, in a boy of thirteen. He became excessively faint very soon after the operation, and there was a little bleeding throughout the whole of the afternoon and day following, which was checked by the introduction of the finger, with pressure on the pudic artery for about half an hour at a time. No farther bleeding occurred after the second till the ninth day, when he became very restless, and there followed a very free bleeding, both from the wound and from the urethra; several clots were passed during the afternoon and evening, the finger having been introduced into the wound several times to favour their escape. There was no recurrence of clots or bleeding after this day. He was kept low for some days, but no cold application used, and he recovered. The following fatal case of secondary bleeding happened to me in 1839 :—Ihad operated on a lad of thirteen years of age with the gorget, and in opening the staff had cut through either the transverse perinaeal or the artery of the bulb, from which there was very free bleeding, but it soon ceased. On the evening of the second day he had pain in the region of the bladder and in the left groin, with tenderness and a good deal of constitutional excitement. Leeches were applied to the bfelly. The symptoms continuing, calomel and opium were ordered on the following day, and he was so much improved the fifth day that the mercurial was left off, there remaining only a little tenderness in the left groin. His urine was now quite natural in colour. On the sixth day, up to which time he had passed water plentifully both by the wound and by the urethra,^ thin slough about the size of the finger-nail came away, and he seemed doing very well; but about noon he had some pain at the lower part of the belly, which was immediately followed by a small motion, accompanied with much straining; and as the urine passed by the wound, a quantity, as much as fill both hands, of very offensive dark-coloured clotted blood escaped with it. He then became easy, but was very faint and pallid, and it was necessary to give him some brandy. On the next day he was tolerably well, free from pain, and did not seem affected by the occurrence of yesterday. It was thought that the clot dis- charged might have depended on bleeding back into the bladder, and that this had been the cause of the irritation on the second evening. On the seventh evening he had a good deal of straining, and passed by the wound about three table-spoonfuls of clotted blood in several lumps, with plenty of water. On the following morning he passed some bloody urine after straining, and the napkin was slightly tinged with fresh florid blood ; he was pallid, his pulse small and quick, and the countenance rather anxious. The same evening, with much straining and a little motion, he passed a clot of four ounces, another an inch and a half long, and as thick as the finger, and a third and smaller clot, at three several times. On the morning of the ninth day, about half-past seven, with much straining and a little motion, he passed about four ounces of cldt with urine by the wound, and a little blood, but no water, from the urethra. He then became very faint and squeamish, and yawned con- tinually, his countenance bloodless, and his pulse very weak and quick. I carefully examined the wound, and found it clean but pale, with a small layer of coagulated blood on the left side, which being disposed to stick, I thought best to leave alone. Between this time and three in the afternoon his bowels were sparingly moved five 336 CUTTING FOR THE STONE; times, and he had passed plenty of water, but neither blood nor clots. On consulta- tion with my colleague, Green, it was determined that the finger should be intro- duced into the bladder, and any clot there detached and broken to pieces, and cleared out by injecting warm water, that the bowels should be quieted with opium, and his powers supported with egg and wine. This was accordingly done; I introduced my finger, but could not ascertain any thing unusual; no water, but a small portion of clot, not larger than half a sixpence, followed its withdrawal. I then passed a catheter by the urethra, and with* my finger in the wound, introduced it into the bladder, and injected by it some warm water twice, the first passed by the wound slightly tinged, but the second was colourless; and the catheter when removed had no appearance of having been in any clot. He slept during the rest of the day, and neither had any more straining nor passed blood, though the napkin was a little stained. About eleven he threw up some beef tea immediately after taking it, as well also porter and brandy and water, which were given at intervals, and then dropped asleep. At four o'clock on the morning of the tenth day his bowels were freely moved without any clot, and soon after he took and kept down an egg and some tea. In the course of the forenoon he passed plenty of water, accompanied with a very offensive discharge, as if from a slough, but without any blood, and seemed better though very languid. As he was fully under the influence of the opium I directed its omission, thinking it might be perhaps the cause of the sick- ness. At noon he was seized with shivering and seemed to be passing'his water; the wound was looked to, a small clot found in it, which being removed, the urine escaped readily, and the shivering ceased. During the day he took some beef tea, porter, and egg, which he enjoyed, and was constantly dozing. He had one motion with much straining, but unaccompanied with bleeding or clots. On the fifteenth day he continued improving, except that the straining continued, for which an opium injection was given with advantage, and he has taken plenty of nourishment, to which first port wine was added, but afterwards changed for sherry. The wound bas become more florid and suppurates freely, and there is a plentiful discharge of 7?iMctenty-second) he was attacked with some bronchial irritation, which continued increasing, not having been relieved by the application of mustard poultice or blister,as he was too weak for any more active means. He continued sinking, and died on the afternoon of the twenty-fourth day, but had not had any recurrence of the bleeding. The examination of this case was most unsatisfactory, as the parts which had been removed that they might be carefully examined, were cut to pieces in the neigh- bourhood of the pudic artery, which was the most important of all. I was therefore unable to ascertain whence the bleeding had originated; but I cannot help thinking it must have been from tin origin of the transverse perinseal artery, and that had I made pressure on it at first, as I-did at last, the boy might have been saved. This plan I should certainly adopt under similar circumstances. At the time I did not recollect the occurrence of after-bleeding in a case of this kind, and when the bleed- ing ceased for a time and the child again began to improve, I had hoped that the danger had passed away. The case is deeply interesting, and I believe not unde- serving the full report I have given of it.—j. f. s.] 2105. Wounding the rectum may happen in various ways j First, at that step of the operation when the operator having made the outer cut, AFTER-TREATMENT. 337 carries the point of the knife into the groove of the staff' for the purpose of opening the membranous part. If the handle of the knife be then too much raised, its point sinks into the rectum. This opening is in general very small, a mere puncture, through which only the intestinal gas and a small quantity of faecal matter escapes into the wound. Second, when in withdrawing Frere Come's lithotome or the common bistoury, the wound first made, is still increased. The pain which accompanies cutting through the neck of the bladder often excites the patient to strain vio- lently, and thereby force the intestines violently into the pelvis, so that the rectum lies as a fold before the prostate. In old persons there is sometimes an enlargement of the rectum, so that'the prostate is usually lodged in a hollow of the gut, which also surrounds the neck of the blad- der on both sides. In such case the rectum must be almost necessarily wounded in the withdrawal of Frere Come's lithotome. If the gut receive the prostate only on one side in such hollow, it is advisable to operate on the right side, and with great care (a). Third, the rectum may be wounded in drawing out a large angular stone; if the wound be small, and near the m. sphincter ani, and the patient young, strong, and healthy, the opening frequently closes of itself without symptoms. Sometimes a fistulous opening remains after the wound in the neck of the bladder, and the membranous part of the urethra has closed, and communicating with the gut like a common rectal fistula, is to be treated in the same manner. Occasionally, the external wound -closes, and there still remains a com- munication between the neck of the bladder and the rectum, which, how- ever, is in general so contracted, that but little urine passes through the rectum, and only a small quantity of fsecal matter by the urethra. De- sault and Dupuytren have in such cases divided the rectum from the wound with success. The common practice is to introduce an elastic catheter into the bladder. According to Kern {b), in a wTound of the rectum, corresponding to the body of the bladder, the buttocks should be raised, frequent injections of warm water, and drawirg off' the urine several times a day with the catheter, should be practised. The bladder is placed higher in children than in adults; therefore, as the parts are cut through from without inwards, or from within outwards, a direotion must be given to the instrument, corresponding to a line supposed to be drawn from the navel to the haunch-bone, so as more certainly to avoid injuring the rectum (c). [Wounding the rectum in performing the operation for the stone is, as far as I know, of rare occurrence. I have seen but two cases in the course of thirty-three years; one was done in introducing the gorget, and the other in making the, second cut with the knife before the gorget was introduced. Th© surgeons under whose care they were, wisely left them alone, and treated them as if no accident had hap- pened. A little faeculent matter passed by the wound in. the perinaeum for a few days, after which the rectum scarred, and no farther inconvenience ensued. I have never seen any instance in which division of the sphincter ani was requisite, and I doubt whether in England such ever occurs. Should I ever meet with a recent case of the kind, I should advise leaving it to nature.—j. f. s.] 2106. When the rectum is protruded by the patient straining during the operation, it must be pressed back and retained by an assistant with a pad upon the right side. Convulsions and fainting require the operation to be quickly finished (a) Deschamps, above cited, vol. iii. p. 8. (b) Above cited, p. 233. (c) Dupuytren, above cited, p. 28. 29* 338 CUTTING FOR THE STONE ; and if that be not possible, and the patient's danger great, the extraction of the stone must be put off. 2107. The-after-treatment in general consists of cooling and mild re- medies. The patient should take an opiate after the operation, and must preserve the most perfect rest of body and mind; for drink he should take a little almond milk, and for food only a little broth, for the first few days. The sponge on the wound should be frequently changed, and the neighbouring parts kept clean. In general the urine begins to flow partially by the urethra the first day after the operation; when the urine is mostly voided by the urethra, the wound should be covered with wad- ding, which is to be fixed with a tightly drawn T bandage, and towards the end of the scarring the wound must be touched with caustic to pro- mote its healing. The cure of the wound is often complete in three or four weeks; sometimes it occupies a month; but in rare cases the wound closes by quick union in from nine to fourteen days (a). I have twice seen the wound healed by agglutination on the fourth day (6). The continued application of cold by means of a large sponge dipped in very cold water, is obviously the most efficient remedy to prevent bleeding and severe trau- matic reaction. [The dextrous performance of the operation for the stone is not all that is neces- sary for the well-doing of the patient, and instances have occurred within the remem- brance of many, in whieh, though ably and quickly performed, and with as little suffering to the patient as possible, and every hope of a favourable result when they were removed from the operating-room, yet have they terminated fatally. In hos- pital practice, I have no doubt this has arisen from stone-patients having been, in most instances, placed in a ward with other patients, where sufficient quietude could not be preserved, and where the sister having only occasionally a single case, had no chance of obtaining sufficient experience in the conduet of a case, which mainly depends on her constant attendance and ability, almost as much, indeed, as upon the good performance of the operation. In consequenee of so much being intrusted, of necessity, to the sister, and so little which might attraet attention being done, few students, on leaving the hospital, know more of a stone-case than the performance of the operation and its result, unless any thing very remarkable should occurduring the course of the cure; and therefore, when settled in practice, and called upon to operate for the stone, although they may perform the operation extremely well, yet they are at a loss to know in what way the after-treatment, under common circum- stances, should be conducted ; and are therefore unable to give directions, or to exert such eontrol over the nurse as may assist to bring about a favourable termination of the case. I am not aware that either in any Lectures on Surgery, or other published works, that these seemingly trifling, though, in reality, very important points in the after-treatment of stone-operations have been noticed, the attention only having been drawn to after-bleeding, peritonaeal inflammation, and some other more striking circumstances of such cases. To fill up this serious gap in the after-treatment, I shall now relate the practice whieh certainly for the last forty-six years, and I have little doubt for a mnch longer period, has been adopted at St. Thomas's Hospital. When a patient is ascertained to have the stone, he is placed in a small ward, con- taining only half-a-dozen beds, and which, during the first part of the after-treat- ment, is kept private and extremely quiet. Here he remains under the watchful eye of the sister, an experienced woman, to whom all the stone-cases are assigned, and who is capable of giving the surgeon a full and sufficient account of the patient's symptoms and sufferings during his absence, and to note any little peculiarity about him, which a nurse unaccustomed to such cases would overlook. Great care is taken in first instructing these women, who usually remain long in this ward; indeed, in thirty-six years the sister has been replaeed only thrice since the death (a) Textok, above cited, p. 34.—Graefe (6) Chelius, TJebcr den Steinschnitt; in in Bernstein, p. 100. . Heidelb. klin. Annulcn, vol. vi. part iv. AFTER-TREATMENT 339 of the sister who had the ward when I first entered the profession, and who spent twenty years there: a sufficient proof of the experience which such persons must acquire. The patient usually remains for ten days or a fortnight, to accustom him to the place and to his attendants; and it is rarely requisite to pay more than ordinary atten- tion to his diet and habits, if he be in good health, excepting his immediate com- plaint. If his sufferings be severe, an occasional hip-bath is used, which has a very soothing effect; and is often extremely serviceable if the preparatory soundings increase, as they will occasionally, his sufferings. I have rarely known it neces- sary to employ blood-letting or other depleting means, though such necessity may possibly occur, but in ordinary cases they are unneedful and improper. An occa- sional clearing of the bowels is, however, requisite; and if the patient have been accustomed to take gin and water, for promoting the action of the kidneys, a prac- tice, with regard to young stone-patients especially, very prevalent, it will be well not to deprive him of it at once, or he will become fidgetty and uncomfortable, but to diminish it slowly, or even to continue its use. Under ordinary circumstances, a stone-patient should not be operated on, except his health be otherwise good. His sufferings from the disease itself will call for the performance of the operation. The state of the atmosphere should, as far as possible, be considered. Temperate weather is the most favourable; for if it be very hot, the patient, in the weak state he usually is after the operation, suffers much from its depressing effects; and if it be very cold, he is liable to chill in the neces- sary frequent uncovering to which he must be subjected to keep him dry during the after-lreatment. On the day previous to the operation, a dose of castor oil should be given to clear the bowels, and the diet restricted to rice pudding and milk, with plenty of barley water or gruel, but the former of the two is most preferred. If the motions be hard and lumpy, castor oil is added to an injection of gruel, which must be thrown up on the morning of the operation, but if not, a simple injection of gruel is sufficient for the purpose of completely relieving the. lower bowel. Immediately after the operation, the patient is put to bed, with his legs straight and close together, by which the surfaces of the wound are brought gently together, and any slight disposition to bleeding checked. A napkin is passed round the pelvis, and brought up between the legs, in the same way as healthy infants are commonly clouted. As it is of great importance that the patient should be kept dry, the napkin is changed every time any urine passes by the wound, and attention is paid to this through the whole course of the treatment. On the evening of the ope- ration day, or the following morning, if there be no bleeding, a piece of lint, folded on the end of the finger, is introduced into the wound, and pressed up the depth of the perinaeum; this is also replaced every time the patient wets, and is continued till the wound heals; its object is to ensure the healing of the wound from the bot- tom, so as to prevent, as far as possible, the production of any fistulous passage, which, under this treatment, is of very rare occurrence. A handful or two of camo- mile flowers thrown into a basin, are sprinkled with spirits of wine, well mixed, so as to be equally moistened, and then put into a thin flannel bag, and having been well heated on a warming-pan, are applied over the belly as hot as the patient can bear, on the evening of the operation day, if there be no bleeding; and this is con- tinued for a week or ten days. If, as sometimes happens, on the second day the wound be swollen, and the urine do not flow through it, no lint is introduced, but a bread-and-water poultice applied, and, as the swelling subsides, the water escapes by the wound. Such is the usual mode of proceeding, and neither is the bed guarded with oiled silk, nor cold sponge, nor any other cold applied even though there were bleeding. Rarely, except under particular circumstances, is any opiate given throughout the cure. The diet for the first two or three days should consist merely of rice or sago pudding, biscuit, toast and tea, or arrow root and milk, with a plen- tiful supply of barley water. As the bowels had been freely relieved, it is unne- cessary to give any medicine before the third day, and then only a little castor oil to act gently. But if there be pain in the belly, or sickness, then the oil must be given earlier, and usually it subsides when the bowels are moved. The urine at first passes frequently by the wound; but usually about the third or fourth day also comes by the urethra; and as more continues to pass by the latter, so does less escape by the former, and, in about a week or ten days, the wound of the prostate 340 CUTTING FOR THE STONE J having healed, the water passes only by the natural passage; and when this hap- pens, the wound is dressed with wax and oil upon the lint introduced, as before. In one instance I have known the water cease to pass from the wound after twenty hours, but this is a rare occurrence. Generally, when the water does not at first flow from the wound, the patient becomes irritable and uneasy, and it is well to introduce the finger, so as to break up any little clot which may stop up the wound, after which it usually escapes freely. Occasionally it may be necessary to resume the gin and water, if the patient flag, which, however, the surgeon himself will attend to in reviewing the state of the health. The patient should be kept in bed some days after the water has ceased to flow by the wound, or, in other words, till it is nearly healed to the surface. If a small sinus should continue open, it is well to twist up a little piece of lint corresponding to its size, which should be dipped in a solution of sulphate of copper, and gently screwed up to its bottom; but, in most cases, a simple dressing of wax and oil is all that is needed. Commonly, in from three weeks to a month, the cure is perfected; the diet having been gradually improved, and porter or wine added according to circumstances.—j. f. s.] 2108. When, after the operation, there is reason to fear active inflam- mation, it must be sought to prevent, it by general and local blood-letting, and by the constant use of cold applications to the perineum. If inflam- mation arise, which commonly spreads over the perineum, it must be met with corresponding antiphlogistic treatment (1). It most commonly depends on the escape of urine into the cellular tissue of the pelvic cavity, when the capsule of the prostate has been opened by a large cut, or by tearing. Old persons, in whom the walls of the bladder are thickened, or otherwise diseased, often die without any active inflammatory symp- toms coming on. Opiate clysters and blisters to the belly are proper in these cases (a). In an erethetic state, which shows itself by a very great degree of general uneasiness, by great wearisomeness of the whole body, by dull pain in the loins, and depression of the powers, with small, contracted, faltering pulse, cooling and mild treatment must be first em- ployed, together with warm bathing and oily mixtures, and if any one organ be specially affected, leeches must be at the same time applied to it (b). Spasmodic symptoms require antipasmodic remedies alone, or in connexion with antiphlogistics, if there be accompanying inflammation. A painful discharge of urine by the urethra, or its complete obstruction may be caused by spasm, by swelling of the wounded parts, or by a collection of clotted blood. According to the variety of the cause, the remedies must be either antipasmodic or antiphlogistic, and the urine must be emptied through the wound by a female catheter passed into the bladder. [(1) "It is a prevailing opinion," says Key, " that stone-patients die of peritonitis brought on by the injury done to the bladder during the operation, a mistake which, though not leading to any serious error in the after-treatment, is so far attended with mischief inasmuch as it misleads the surgeon from the true cause of the fatal event. I will not venture the assertion, that inflammation of the peritonaeum is never a sequela of lithotomy, but that it is an extremely rare occurrence, and still more rarely the cause of death, examinations post mortem have fully convinced me. During the ten years I have been at our hospitals, I have never yet seen an unsuccessful case, examined after the operation, in which inflammation of the peritonaeum could be regarded as the cause of death; and as invariably I: have found that one circumstance was uniformly present, namely, suppurative inflammation of the reticular texture surrounding the bladder. * * * Inflammation spreading rapidly through these cells will quickly effect a surface much greater than that of the peritonaeum, and I (a) Samuel Cooper, First Lines of Surgery, p. 775. Seventh Edition. 1840. (b) Zang, above cited, p. 239. AFTER-TREATMENT. 341 have witnessed," says he, "symptoms as acute, pain as severe, and the peculiar depression attending peritonitis, as marked in the reticular inflammation as in the most acute and fatal case of inflammation of the abdominal cavity. * * * la the inspection of those who die after lithotomy, it is not sufficient to look into the peritoneal cavity, to open the bladder, or to examine the state of the wound; the peritonaeum lining the lower part of the abdominal muscles should be stripped off, and the source of evil will be then laid open. The finger will enter a quantity of brick-dust coloured pus in the cellular substance around the bladder, and if con- siderable force has been used in the extraction of the stone, will readily find its way towards the wound in the perinaeum; the barrier between the adipose structure of the perinaeum and the reticular texture of the pelvis being broken down, the sup- purative inflammation spreads rapidly along the latter, and may be traced, in some cases, between the perinaeum and abdominal muscles as high as the umbilicus, in one case I have seen it extend to the diaphragm." (p. 18-21.) "All that I have been able to observe for many years past," says Brodie, "has confirmed me in the opinion, that an incision of the prostate, extending into the loose cellular texture surrounding the neck of the bladder is replete with danger to the patient. Such a division of parts is never necessary where the calculus is of moderate dimen- sions ; but it cannot be avoided where it is of very large size; and hence the extraction of stones of this description can never be accompanied without a great probability of the patient not surviving the operation. "The symptoms which arise in these cases are not well marked in the first instance. There is some heat of skin, and generally an absence of perspiration; there is usually an abundant flow, of urine through the wound. The pulse, as to frequency, is somewhat above the natural standard; and the patient, although free from suffering, has no disposition to sleep. This state of things continues for twenty-four or even forty-eight hours after the operation; then the more characteristic and alarming symptoms show themselves. The pulse becomes more frequent, rising to 90, 100, and at last to 140 in a minute; the heat of skin becomes still greater, the tongue dry, the countenance anxious. Afterwards, as you count the pulse, you find every now and then a beat weaker than the rest, and then there are complete intermissions. At first the intermissions are not more than one or two in a minute; by degrees they become more frequent, until they occur every third or fourth beat. There is an occasional hiccough; the patient complains of some de- gree of tenderness in the lower part of the abdomen, especially in the left groin; the belly becomes tympanitic, that is the stomach and intestines are filled with air, the distention of the belly increases, the hiccoughs are more frequent, the pulse con- tinuing to intermit, becomes weak and fluttering. In some instances, the patient retains his understanding even to the last; while in others he falls into a state of low delirium previous to death. Occasionally in the progress of such a case, the patient has a severe rigor, and sometimes he complains of a pain in the loins. Where these symptoms begin at an early period, he may die within forty-eight hours from the time of the operation; but in other cases, death may not take place for four or five days, or even for a week. On dissection you find the cellular membrane round the neck of the bladder, and between the prostate and the'rectum, bearing marks of inflammation, infiltrated with lymph and serum, and to a greater or less extent, converted into a slough. If death has taken place at an early period, the in- testines are found distended with air, and there is a very slight effusion of serum in that part of the peritonaeum, which distends into the pelvis. But if the patient has laboured under these symptoms for many days before he dies, the peritonaeum, where it is reflected from the bladder to the rectum, is seen of a darker colour than natural, and incrusted with lymph ; and at a still later period there is"the appearance of inflammation, to a greater or less extent, throughout the peritonaeum generally. But the peritonaeal inflammation is evidently not the primary disease; it is the inflammation and sloughing of the cellular membrane of the pelvis, which has induced inflammation of the adjoining portion of the membrane. Something also is to be attributed to the tympanitic distention of the intestines, which, if continued for a considerable time, is always liable to be attended with tenderness of the abdomen, and some degree of peritonaeal inflammation. It is important that you should not fall into the error of regarding such cases as I have just described, as cases of simple peritonaeal inflammation; for the remedies which would be useful in the latter case are 342 CUTTING FOR THE STONE, THROUGH injurious here. The abstraction of blood, or even the operation of an active purgative, will cause the patient to sink more rapidly, tending only to hasten his death. The proper system to be pursued, is the opposite to that of depletion. The patient should take such nutriment as his stomach is capable of digesting. The bowels may be kept open by injections, or by the exhibition of some very gentle purgative; and ammonia, wine, and brandy are to be administered, when the state of the general system indicates that stimulants are necessary." (p. 327-30.)]. 2109. The bleeding -which occurs at various periods after the opera- tion, requires a different mode oftreatment according to its degree. If slight it may be considered useful as a local blood-letting, and as tran- quillizing the patient. A severe bleeding, when coming on soon after the operation, if it do not yield to the use of cold applications, requires the ligature, if the seat of the bleeding vessel will permit it, or pressure as already directed. In this case, as well as when pressure is also applied after the operation, the instrument used must be continued in its proper place, as long as seems necessary for the certain obliteration of the vessel. Bleeding from the vessels of the bladder requires, besides strict rest and a cooling treatment, cold applications to the belly, and in cases of necessity injection of cold water, or solution of alum. In persons whose blood is thin and watery, their eyelids puffy and semi-trans- parent, who are often attacked with bleeding from the nose and gums ; a constant bleeding often comes on after the operation, which is nearly always fatal, and like any parenchymatous bleeding, must be treated with tonics (a). 2110. Abscesses sometimes form about the neck of the bladder, which must be encouraged to discharge their pus. If fistula should remain, it must be treated as already directed (par. 2105); frequently it is in- curable. Incapability of holding the urine and impotence, which rarely continue after the lateral operation for the stone, depend upon the great bruising and gangrenous destruction which the neck of the bladder has suffered' from the large size of the stone and the violence of the extension. Strengthening remedies, internally and externally, as in ischuria paraly- tica, are the alone means which may here perhaps be useful. 2111. If the disposition to form stone continue after the operation, it must be counteracted by either of the already prescribed rules (par. 2011-13). An instance of remarkable disposition to form stone is mentioned by Chari.es Phillips (6), in Vhich in the space of six years, on lithotomy and four lithotripsies were required. To the works already referred to on the lateral operation for the stone, the follow- ing may be added:— Mery, J., Observations sur la maniere de la tailler dans les deux sexes pour l'Extraction de la Pierre, pratiquee par Frere Jacques. Paris, 1700. Morand, S., Opuscules de Chirurgie. vol. ii. p. 51. Garengeot, De l'Operation laterale corrigee. Paris, 1730. Gunz, De Calculum curandi viis, quas Foubert, Garengeot, Perchet, Le Dran et Le Cat reperierunt. Lipsiae, 1740. Pallucci, N. J., Nouvelles Remarques sur la Lithotomie, &c. Paris, 1750. 8vo. Albin, R. S., Dissert, de variis Calculi secandi methodis. Ludg. Bat., 1754. Camper, Demonstrationes Anatom. pathologicae, lib. ii. Pouteau, Sur l'Operation de la Taille; in Melanges de Chirurgie, p. 197. Lyon, 1760. (a) Deschamps, vol. iii. p. 29. (b) Gazette Medicale, vol. ii. p. 534. 1834. THE PERINEUM INTO THE BODY OF THE BLADDER. 343 Seiller, Dissert. Cultrorum ceratotomorum etcystidotomofum historia. Witten- berg, 1805. Dorner, Uber die Wahl einer Steinschnittmethode; in von Siebold's Chiron, vol. i. part i. Thomson's John, M. D., Observations on Lithotomy, &c. Edinburgh, 1808. 8vo. Cooper, Samuel ; in Med-Chir. Trans., vol. viii. p. 206. Richerand, Memoire sur l'Hemorrhagie apres l'Operation de la Taille laterale; in Mem. de la Soc. d'Emulation, vol. i. p. 145. [Dudley, B. H., On Nature and Treatment of Calculous Diseases. Lexington, Ky., 1836. 8vo. Bush, Jas. M., Observations on the operation of Lithotomy, illustrated by cases from the practice of Prof. Dudley, in Transylvania Journal of Medicine for .1837.—g. w. n.] 2112. Incidental to the history of the lateral operation for the stone, are the methods of opening the body of the bladder from the perineum, which originated in the attempts made by Bamber, Cheselden Le Dran, Douglas, and Morand, to discover Rau's operation, which was wrongly believed to consist in opening the body of the bladder (a). Foubert proposed a particular mode of operating, in which, after the bladder had been largely distended by drinking, by injection, or by hold- ing the water, a long grooved trocar was thrust horizontally into the bladder in the middle of the space between the m. erector penis and m. accelerator urine, from two to three lines from the ischial tuberosity and an inch from the anus ; and after withdrawing the stilette a little, with a peculiarly formed knife carried along the groove of the trocar, the open- ing into the body of the bladder from below upwards, and in withdraw- ing the knife the outer wound was dilated. A gorget was then intro- duced on the groove of the trocar, with which, if necessary, the wound was farther enlarged, and upon it the forceps passed (b). Thomas (c) made the cut from above downwards by means of an instrument re- sembling Frere Come's lithotome. 2113. The danger of bleeding, the difficulty in extracting the stone, the wounding the rectum, and the other accidents, and their consequences which frequently accompany the lateral operation for the stone, have led to the practice of cutting for the stone through the rectum (Lithotomia recto-vesicalis.) This operation was first proposed by L. Hoffmann {d), who gave reasons for its preference over the others, although the proposed operation is more uncertain in its results. Sanson (e) claims it as his own discovery, and describes his mode of proceeding. It is in especial favour with Vacca Berlinghieri (f) and others, and performed with success. (a) Douglas, above cited.—Le Dran, Pa- rallele des differentes mmieres de tirer la Pierre horsde la Vessie, p. 109. Paris, 1730. (,b) Foubert, Nouvelle Methode de tirer la Pierre de la Vessie ; in Mem. de l'Acad. dc Chirurgie, vol. i. p. 65, pi. i.-viii. Kes. seluing, Dissert Historia et examen Me- thodi Foubertiani pro extraciione Calculi. Halte, 1736. (c) Thomas ; in I.ouis, in Mem.de l'Acad. de Chirurgie, vol. iii. p. 653. Dkschami's, alove cited, v>l. ii. pi. v. f. T2. (d) Von einer neuen Methode den Stein zu schnciden; in Vermischten Schriflen, herausgegeb. von. H. Clavkt. Miinster, 1791. vol. ii. p. 511. (e) Des M >yens de pnrvenir a la Vessie par le Rectum, avantages et inconveniens attaches a cette Methode pour tirer lea Pierres de la Vessie. Paris, 1817. 4to. (/) Sanson, l)es Moyens de parvenir a la Vessie par le Rectum, &c, suivie d'un Me. moi^e snr la Methode d'extraire la Pierre de la Vessie nrinaire par la voie de 1'Intestin Rectum, de And. Vacca Berlinghieri, tra- duite de l'ltal. par Blaquiere. Paris,1821.8vo. 344 CUTTING FOR THE STONE, Martin (a) lays claim to the discovery of this operation: he made his first ex- periment on the dead body in 1786. But Hoffmann lectured on the subject in 1779. That the first notion of the operation of cutting for the stone by the rectum cannot be ascribed to Vegetius (b), as the Editor of the Article Lithotomie in the Diet. des Sc. Medic, vol. xxviii. p. 421, imagines, Vacca Berlinghieri has sufficiently proved (c). [" In the case of a thin person, with a stone of so large a size, that the extraction of it by the usual method, would be either impracticable, or attended with the great- est risk to the patient's life," Brodie says, ''it may be a question, whether there is not a better method of proceeding (than the high operation) in the recto-vesical ope- ration; in which the incision of the perinaeum is made to extend through the tunics of the rectum and the sphincter ani muscle. Here the parts which afford the chief resistance to the extraction of a large stone are divided; and, although the incision of the neck of the bladder extends beyond the boundaries of the prostate, the ill con- sequences arising from the escape of urine into the cellular membrane, are likely to be in great measure obviated in consequence of the free opening which has been made into the rectum." Brodie performed this operation on one occasion in which the stone was supposed to be very large, but did not so turn out, and the patient, who had suffered from stone more than twenty years, died in about three weeks with ab- scesses in the kidneys, and on one side of the pelvis, (pp. 347, 48.) In another case, a man between sixty and seventy, whom he operated on with Blizard's knife, and on whom with much constitutional excitement, the abdomen was tense and swollen, and there was great danger, Brodie cut through the rectum with a probe-pointed-bis- toury on the fourth day,'and the patient did well. Solly, one of our assistant surgeons, also performed this recto-vesical operation in a case where the stone was presumed to be very large; but it was not large. The case went on well, and recovered without any untoward circumstances.—j. f. s.] 2114. Sanson has proposed two different modes of penetrating through the rectum into the bladder. After previously dividing the m. sphincter ani and the lower part of the rectum, in the direction of the raphe, towards the root of the penis, the prostate, and part of the lower wall of the bladder is laid bare, and then upon the groove of a staff introduced into the bladder, the prostate is to be divided in its mesial line; or the knife may be passed behind the prostate through the wall of the bladder into the groove of the staff and the base of the bladder divided to a certain extent. The latter method is fully described by Sanson; the former is rather indicated. The staff when introduced is to be held upright, the left forefinger, with its volar surface upwards, is to be introduced into the rectum, and upon it the blade of a straight bistoury laid flat; its edge is then turned up, and with a single cut the outer sphincter muscle, together with the lower part of the rectum, is cut through in the direction of the raphe. The groove of the staff is now sought for with the finger behind the exposed prostate, the point of a bistoury introduced upon it, and as it is pushed along the groove, a cut is made in the lower wall of the bladder, which commencing behind its neck, passes in the mesial line to the midst of the space between the two ureters, through which the stone is extracted. Vacca Berling- hieri has specially defended the first mode, and has fully set forth his preference of it both by reasoning and experience, so that his essay may be considered the best guide for recto-vesical lithotomy. 2115. The patient must be placed and bound as for the lateral opera- tion ; a staff is passed into the bladder, and given to an assistant, who holds it firmly and perpendicularly so that its groove corresponds to the mesial line of the urethra and the raphe. The operator then takes a straight bistoury with his right forefinger and thumb, where the blade (a) Nouvelle Methode de faire l'Operation (ft) Mulomedicina, cap. xlvi. lib. i. Basil. de la Taille; in Revue Medicale, vol. ix. p. 1574. 225. 1822. (c) Above cited, p. 72. THROUGH THE RECTUM. 345 meets the handle, and lays its blade flat on the volar surface of the left forefinger, in such way that both its edge and point are covered; the finger and knife are then passed into the rectum, and carried upwards ten or twelve lines, the dorsal surface of the finger corresponding to the hollow of the sacrum. Whilst the operator presses the hind wall of the bladder with this finger, he turns with his right hand the edge of the bistoury upwards, and with the forefinger pressing its back, he thrusts its point through the front wall of the rectum, and as he withdraws the knife, cuts through the rectum, the external sphincter muscle and the cellular tissue covering the urethra. The operator now leaves the bistoury with the left forefinger, turns the dorsal surface of this finger towards the left and its cubital surface upwards, carries its tip into the wound of the sphincter, and places his nail (which in this operation should be always done) in the groove of the staff, which can be felt through the wall of the urethra. Guided by the nail of the left forefinger, the point of the bistoury, with its edge downwards, is Carried through the wall of the urethra into the groove of the staff, and supported on the nail, is pushed forwards in a corresponding direction to the raphe, by which the neck of the bladder and the prostate are divided to a greater or less extent, ac- cording to the presumed size of the stone. The staff is now removed, and the finger passed through the wound into the bladder, by which is ascertained whether the wound be sufficiently large, or whether it require enlargement, which may be easily done with a common or button-ended bistoury introduced on the left forefinger. The forceps are passed in upon the same finger, and the stone extracted according to the rules already given. After the wound has been Cleansed, the patient is to be put in the same posture as after the lateral operation. Any dressing of the wound is objectionable. Cutting into the prostate with Frere Come's lithotome, introduced into the groove of the staff after the membranous part is opened, as Dupuytren and others do, is less convenient than with the bistoury. Geri's (a) mode of introducing a gorget an inch and three quarters broad at its base, three inches and a half up the rectum is objectionable, as straining and purging may occur during the operation, and as the rectum is only widened at the expense of its length, and is therefore short and folded, and the peritonaeum approaches the neck of the bladder, so is the peritonaeum the more liable to be wounded, and certain parts of the rectum must be left undivided. Vacca Berlinghieri mentions the case of a child operated on by Geri, which died twenty-four hours after, and both these accidents had happened. These objections apply still more to the method of Sleigh (b), who widened tfi6 sphincter and the rectam with Weiss's speculum am, found the hind edge of the prostate with the tip of the left forefinger, and then without touching the gland, cut through the wall of the rectum and bladder with a convex scalpel, concealed in a spring sheath, upon the groove of a staff first introduced. 2116. The after-treatment has the same object as in the lateral opera- tion. The patient should take an opiate; he should use mucilaginous, diluting drinks; at first should take exceedingly little food ; and, by a proper treatment, it should be endeavdured to keep off inflammation, which is more necessary in this than in the lateral operation, because it is accompanied with very little loss of blood. When suppuration comes (a) Rep. Med.-Chir. de Turin, No. 11, p. lfio. (b) An Essay on an improved Method of cutting for Urinary Galculij or the Posterior Operation of Lithotomy* London, 1824. 8vo: Vol. iii.—30 346 CUTTING FOR THE STONE ; on, usually about the seventh day, it is necessary to touch the wound with caustic at every part of the cut in the rectum; for this purpose, the edges of the wound are drawn apart a little, and a wooden canula, having a bit of caustic in it, is passed up, by which the cure is promoted. 2117. The advantages of cutting for the stone through the rectum are stated to be, first, that the patient is in no danger from bleeding; second, that the bladder is reached through the least thick parts; third, that the stone is most easily found, grasped, and pulled out, even when of large size, because the wound corresponds to the largest space of the pelvis; fourth, that no infiltration of urine follows. Geri {a) and Scarpa (b), the most violent opposers of this practice, bring against it, first, that the wound and irritation of the rectum produce intermitting, irregular, febrile action after the operation; second, that one or both the vasa deferentia may be wounded, and by the pulling and stretching in the removal of the stone, are so much injured, that inflam- mation, swelling, wasting of the testicle, impotence from the destruction, adhesion or contraction of the mouths of the vasa deferentia may ensue; third, that the neighbouring parts are irritated by the use of the caustic; fourth, that by the entrance of the faecal matter into the bladder, there is fear of its internal coat being destroyed, of dangerous irritation, and of fseco-urinary fistula; fifth, the recovery is more tardy. Scarpa considers this operation even more imperfect than that of Celsus. 2118. These objections are not all of equal weight. The intermittent fever is, according to Vacca's observations, in but very few cases directly connected with the wound of the rectum. The injury of one of the vasa deferentia, and the consequences based thereon, Scarpa has not supported by cases; this wound may scar or remain fistulous, and its orifice may still perform its functions; besides, the operator can even avoid this injury, and also in the lateral operation the vas deferens and even the vesicula seminalis may be wounded. The irritation of the neighbouring parts may be prevented with caustic by Vacca's method. The entrance of faecal matter into the bladder can only happen by cutting through its base, and not by Vacca's proceeding, as it is prevented by the valve-like protrusion of the wall of the bowel cut into below ; and still more as the excrement, in consequence of the division of the sphincter, meets with less obstruc- tion from the natural passage. Fistulas indeed not unfrequently remain after this operation, but they communicate only with the membranous part of the urethra; a little stool is passed rarely by the urethra, and but little urine by the rectum, and nothing gets into the bladder. On this point Wenzl's (c) remark is important, that the external cut should always be made sufficiently large, by which in part, during the operation, the sphincter causes less obstacle, but it especially prevents the external wound contracting more quickly than the inner. The cure is indeed tedious in many cases, but in others has been observed to be as quick as in the lateral operation. As to the other objections, for instance, if the stone be very large, that the whole prostate must be cut through, the peritoneum may be wounded, the introduction of the instruments is not (a) Repert. Med.-Chif. de Turin, No. 11-18. (b) Sag-gio di Os?ervatione sul Taglio (c) Geschichte eines Steinschnittes durch Reito-Vesicale per l'Estrazione della Pietra die vordere rectovesical Methode; in N. della Vesica Orinaria. Pavia, 1823, fol. Chiror., vol. ii. p. 181. THROUGH THE RECTUM,—"WHEN PREFERABLE. 347 easier, and the pain in the glans penis after the operation is very violent; these, under corresponding circumstances, apply to the lateral operation, and in regard to the complete division of the prostate, it must not be overlooked that here, perhaps, infiltration of urine is less to be feared than in the lateral operation, because the cut being in the bottom of the bladder, the urine more readily escapes (a). 2119. If recto-vesical lithotomy be considered in reference to the re- sults obtained to the present time, it is found to vary considerably with different operators. Some consider it more successful, some less suc- cessful, than the lateral operation. It has indeed its weak points, and in general must be put after the lateral operation, but it has twro indisputable advantages, to wit, the slight danger there is to life, and that the bleed- ing is not dangerous. Therefore, in particular eases, and where, on ac- count of the size of the stone, the cut above the pubes is required, and the walls of the rectum are healthy, it appears preferable to the high and lateral operation, as also in old persons, and those who have little blood, with a more than moderately-sized stone. The following writers may be also referred to on this subject:— Noethig, Ueber die verschiedenen Methoden des Blasensteinschnittes, besonders fiber den Steinschnitt durch den Mastdarm nach Sanson. Wurzb., 1818. Riberi; in Repertorio Medico-chirurgico de Turino. No. 31-33. Vaca Berlinghieri, Memoria sopra M metodo di estrare la Pietra della Vesica orinaria per la via dell' intestino retto. Memoria terza. Pisa, 1823. Farnese, Essame delle osservatione sul Taglio retto-vesicale dal A. Scarpa. Milan, 1823. Compte-Rendu Medico-Chirurgical dies Observations recueillies a. l'HcVpitai'de la Charite de Lyon. Sec. patrie, 1823.. Sanson, Compte-Rendu de la Pratique Chirurgicale die I'Hotel Dieu de Lyon— Archives generales de Medecine, vol. vi. p* 83. Scarpa; in Annali Universali de Medicina, vol. xxx. p. 125. 1824. Thomson, Will., A Probatory Essay on the Extraction of Calculi from the Uri- nary Bladder. Edinburgh, 1825. Koenig, Ueber einigen Methoden Harnsteine aus der Blase zu ziehen; in von Graefe und von Waltber's Journal, vol. viii. p. 530. Journal Complementaire du Dictionnaire des Sciences Medicales; Barbantini, vol. vi. p. 79.—Williaume, vol. x. p. 180.—Camoin, vol. xii. p. 19.—Dupuytren et Sanson, vol. xv. p. 86-87.—Pezerat, vol. xviii. p. 128. Heinecke ; in Journal von Graefe und von Walther, vol. v. p. 305. Gustorf ; in same, p. 510. Behre ; in Heidelb. Klinisch, Annalen, vol. i. p. 453. Royer Collard, Clinique Chirurgicale de I'Hotel Dieu ; in Report, gen. d'Anato- mie et de Physiologie pathologique, etc., vol. i. p. 234. 2120. Vacca Berlinghieri's (b) most recent practice still remains to be noticed, which without having the disadvantages, of the recto-vesical operation, unites all the advantages, and resembles the coup de mailre proposed by Marechal in the great apparatus (par. 2066.) The first cut, from twenty to twenty-two lines long, extends from the edge of the rectum, along the raphe to the scrotum, divides the skin, the fibres of the m. levator ani and transversus perinei, which with the m.. accelerator urine, the urethra, and the m. erector penis form a sort of triangle in the perineum. The left forefinger introduced into the front of the wound, seeks for the groove of the staff, which is held upright, passes the knife (a) Journal Complement, du Diet, des Sc. tiquer l'Operation de la Pierre, publ. par Med., vol. xvii. p. 128. 1823.—Dupuytren, Begin et Sanson, p. 13. Memoire sur une Nouvelle Maniere de pra- (b) DellaLitotomia nei due Sessi. Quarta Memoria. Pisa, 1825. 348 CUTTING FOR THE STONE IN WOMEN, into it, and therewith cuts into the urethra to the extent of the outer wound. A knife with a blunt beak, about two lines long, is inserted into the groove of the staff, at the lower part of the wound; the staff is then raised towards the pubic arch, slightly inclined towards the operator, and then pushed about an inch deep into the bladder. Without changing the posi- tion of the staff, the handle of the knife is to be raised a little towards the scrotum, by which its back is jammed against the groove of the staff, and in drawing it out, the neck of the bladder, the prostate, the membranous part and the cellular tissue beneath it are cut through. If the wound be not sufficiently large, it maybe easily enlarged in the usual way. In withdrawing ihe stone, the blades of the forceps should be directed to- wards the angles of the wound. L. Balardini (a) has given an account of eight cases treated in the same man- ner. According to Pantaleo (b), the oblique cut in the direction of the outer wound should be made with a double-cutting bistouri cache, through the upper and lower part of the prostate. Here also must be mentioned Dupuytren's proposal, which he pursued very suc- cessfully, but has not made known publicly. He made a cut into the raphe opposite tfie staff held vertieally, then with the bistoury penetrated the groove of the staff, and passed upon it into the bladder Frere Come's bistouri cache, then turned the edge of the instrument upwards, for the purpose of dividing the neck of the bladder as the bistoury is withdrawn (c). B.—Of Cutting for the Stone in Women., Louis, Sur la Taille des Femmes; in Mercure de France. Decembre, 1746. Masotti, La Litotomia delle Donne perfezionata. Firenza, 1764. Platner, Progr. Historia literario-chirurgica Lithotomiae Mulierum. Lips., 1770. Cronenberg, Historia Lithotomiae in muliere factae. Halae, 1811. Behre, Dissert, de Lithotomia muliebri. Kilias, 1822. Behre, Versuch einer historisch kritischen Darstellung de Steinschnittes beim Weibe. Heidelberg, 1827. 8vo. v,on I£ern, above cited, p. 149. 2121. The various methods and modes of proceeding in the operation of cutting for the stone in females may be most conveniently brought to- gether under the following heads:— First. The cu,t below the arch of the pubes, with the divisions of the urethra and neck of the bladder. a. The cut made as in the lateral operation. 6. The horizontal cut on one or both sides, with or without dilating. c. The vertical cut upwards. d. The vertical cut downwards. Second. The cut below the pubic arch, without division of the urethra. a. The vestibular cat of) Celsus and Lisfranc. b. von Kern's method., c. The vagino-vesical operation. Third. The cut above the pubic arch. [It may be well to notice, here Astley Cooper's observation, that women suffer more from stone in the bladder than men, and that " in addition to the symptoms (a) Annali Universali di Medicina, vok (c) Sanson, above cited, p. 48.—Salzburg alvi. p. 23a 1828. Med.-Chir. Zeitung, vol. i. p. 285. 18ia— (J$ Lancet^ X833-.4, vol. ii. p. 557. Royer-Collard, above cited, p. 500. BY THE LATERAL OPERATION. 349 observed in the male, as the irritability of the bladder increases, the pain during micturition is excessive, and there is agonizing suffering after the discharge of the urine from bearing down of the bladder, uterus, and rectum, with a sensation of their being forced through the lower opening of the pelvis. The retention of urine becomes imperfect, and the person is always wet, and smells offensively of urines The sufferings of the patient at length renders her incapable of moving from her bed." Brodie observes, that "in women, calculi of a small size are expelled as they are in the male sex, without ulceration or other injury to the urethra, and without the patient suffering any inconvenience afterwards. Calculi of very considerable size occasionally escape from the female bladder; but the natural cure in these cases is effected by a less simple process." In one case he mentions "a large calculus was found in the vagina, which was extracted with the fingers, the urethra and vagina had ulcerated, and the calculus had passed through the ulcerated opening." (p. 350.) A similar case is mentioned^by Astley, Cooper, " in' which the stone" was placed half in the urethra and half in the vagina; the extremities of the stone were large, and connected by a narrow portion which passed through an ulcerated, open- ing in the under part of the urethra." (p. 298.)] 2122. Cutting for the stone in women by the lateral operation is per- formed in the following manner:— After the patient has been bound and properly fixed' in the same- position as in operating on the male, the labia, are separated from each other, the operator passes a straight staff through the urethra into the bladder, holds it with his left hand in such way that the groove may be directed outwards and downwards, and its convexity pressed against the lower edge of the pubic arch, and passes on it a common bistoury, or the knife used in the lateral operation^ or even a gorget with the edge directed downwards and outward's, between the vagina and; the ascend- ing branch of the haunch-bone, up< to the closed end of the staff. In withdrawing the bistoury, its point must be sunk for the purpose of enlarging the cut. If Frere Come's lithotome be-used, it must be introduced closed: through the urethra into the bladder, after setting it at a number corres- ponding to the size of the stone, pressed against the pubic arch, and; withdrawn, whilst the blade is projected, in such direction that the urethra and neck of the bladder may be divided obliquely downwards, and outwards, as when the bistoury, is employed. The forceps are then< introduced on the finger or on, a gorget, and the stone drawn out according to the rules already laid down. In this mode of operating there is danger of wounding the vagina or' the pudic artery ; and in removing a large stone, there is fear of irritating the cellular tissue attaching the urethra and of palsy of the neck of the' bladder, in consequence of the bruising and dragging which it suffers {a). 2123. In the horizontal cut on one (usually the left) or on both sides,, the cut is made either with a narrow blunt-ended^ bistoury, with a com- mon stone-knife, with a cutting gorget upon a staff, or director, of which', the groove is directed towards the side ; or with Frere Come's lithotome,. or with a proper, single or. double-cutting instrument, and its enlarge-. ment effected with the gorget, the finger, the forceps, or the dilators. In this mode of cutting, the vagina indeed is- safe from, injury, but damaging the pudic artery is more to be dreaded. (a) Klein, Prakt. Ansichtcn u. s. w., partii., p. 1.—Schreger, CJiirucgiscke. Versuche,, vol. ii. p. 132. 30* 350 CUTTING FOR THE STONE IN WOMEN, Le Cat's method with the grooved staff.—Horn's dilating lithotome.—Franco's cutting forceps.—Louis and Flurant's double-edged lithotome cache.—Le Blanc's single-edged lithotome, and the like.—Compare also Behre. [Liston employs the horizontal cut, but not to the extent here mentioned. He says:—" The best mode of extracting foreign bodies from the bladder is to widen the urethra gradually by means, of the screw-dilator, then by the introduction of a straight blunt-pointed knife to notch the neck of the bladder slightly towards each ramus of th© pubes, so as to divide the dense fibrous band'eneircling it; the dilata- tion is continued, and in a few minutes the finger can be admitted; the stone can then be readily grasped by a pair of forceps, and it is astonishing how large a body may be removed by these means. Incontinence of urine may follow the operation from the distention of the sphincter of the bladder; but in a few weeks this will generally cease. The mode of proceeding above recommended is by much to be preferred over the mere dilatation, as being less painful and more rapid in execution; and' looking to the after-consequences, it is undoubtedly preferable to extensive incision of the neck of the bladder with or without wound* of the. vagina." (pp. 525, 26.)], 2124. In the vertical cut upwards-, formerly advised' by Colot (a), and recently-by Dubois, after the patient has been properly placed, a staff is introduced into the urethra with its groove upwards; and whilst the operator holds it with his left hand^, he presses its back against the lower wall of the urethra, by which its canal is expanded for the purpose of its more ready division. A narrow-pointed single-edged bistoury, with its edge a. little directed- to the left so as to avoid the clitoris, is now passed in, and whilst the two instruments form an angle, the point of which corresponds to the neck of the bladder, and the base of the perineum, the canal of the urethra and the neck of the bladder are divided. After the knife has been withdrawn, a gorget is introduced on the groove of the staff,and upon it the forceps (b). Richerand (c) and Dupuytren em- ploy for thjs operation Fre^e Come's lithotome, which having been intro- duced, through the urethra into the bladder with its edge above, and gather inclined to the side, is withdrawn, whilst its blade is projected. [Brodie performed an operation which is a modification of the vertical cut upwards. He says, he " was, informed it, had been adopted by an eminent pro- vincial surgeon, and had not been followed by the usual incontinence of urine. " I introduced," says he, "a bistouri cache into the urethra, having previously fixed the screw in the handle of the instrument, so that the cutting edge could not be made fo project more than to a very small extent; perhaps to about one-sixth of an inch. Then, drawing out, the bistouri, with the- cutting edge turned directly upwards, I endeavoured to divide the membrane of the urethra immediately below the sym- physis of the pubes, without- allowing the incision to extend into the contiguous cellular structure. The next step of the operation was to introduce Weiss's dilator, and-dilate the urethra, so as to allow of the introduction of the finger, and afterwards eftthe forceps, into the bladder. As the urethra now offered no resistance, this dila- tation was. readily effected in the course of a, few minutes, and thus the stone was extracted, The patient did not,suffer from actual incontinence after.the operation; she could not, however, retain it for so long a time as before the disease existed; I believe not longer than two hours, But I have performed the same operation in several other cases, with a still more favourable resulu'* (p. 354.)] 2125. This operation has the following advantages:—The lower part of the urethra has not any bone beneath it, it- is very supple and yields below. .After the operation, the uninjured lower wall of the urethra forms a groove over whieh the urine flows out without disturbing the («) Ambr. Parei, Opera, edit. Guille- (b) Dupuytren, Lithotomie, 51. Weau, lib, xvi. cap. xlvii. p. 506. (c) Nosograpbic Chir., vol. iii. p., 558. Fifth Edition. BY THE VERTICAL CUT DOWNWARDS. 351 cure of the wound above, the healing of which may be assisted by the pressure of a sponge introduced into the vagina. Further, the trunk and large branches of the pudic artery are preserved from, injury, and in the event of any of its minute terminal branches bleeding, they are readily stanched by pressure against the arch of the pubes. Great as these advantages are, it must, however, be remembered, that large stones can- not be withdrawn without considerable bruising of the neck of the bladder, and tearing the natural connexions of the urethra, the conse- quence of which is incurable incontinence of urine (a). 2126. The vertical cut downwards may be made on the groove of a male staff, held upright, and its concavity pressed against the aroh of the pubes, with a common bistoury; or. Frere Come's lithotome may be preferred, with which the urethra, the neck of the bladder, and the cor- responding wall of the vagina may be cut through downwards in their mesial line. This method corresponds to the recto-vesical operations on the male; by it a sufficiently large wound may be made without danger of bleeding, and the largest stone may be extracted with ease, as experi- ments on the dead, and successful results on the living, have satisfied me. That incontinence of urine is to be feared with a free cut, and that the danger of a vesico-vaginal fistula is greater than in the common mode of cutting the bladder and vagina is refuted, at least by my experi- ence, which especially determines me to consider this, as the most preferable mode of operating {b). Falconet (fc)>rfieretofore recommends this practice. Bromfield (d) mentions that he saw a surgeon introduce one blade of a pair of button-ended scissors into the urethra and the other into the vagina, and divide the under part of the urethra, up to the entrance of the vagina, to the extent of an inch at least. According to Bromfield, such a cut could never again unite, the contrary of,bwhich my observations prove; but he says, as the neck of the bladder had the major part of its sphincter: muscle not divided* the patients in general kept their water pretty well. 2127. The cut below the pubic symphysis, without dividing the urethra and the neck of the bladder, is the method of Celsus. The stone must be pressed against the neck of the bladder in; girls by the -finger in the rectum, and in women by the finger in the vagina, and the stone cut on in the one on the under arid left side, andin the other between the urethra and the arch of the pubes. The great objection to this method is self- evident; the pudic artery, the vagina, and even the rectum, are exposed to injury, on which account this,operation-is generally discarded (e). 2128. Lisfranc's vestibular cut is to be considered as a modification of Celsus's operation. After the patient has- been placed in the usual posture and bound, two assistants^ draw the labia apart:. The operator standing between the legs of the patient, introduces a common male staff through the urethra into the bladder with its convexity upwards. An assistant then grasps the handle of the staff, and draws.the urethra and (a) Bf.hre, p. 129. endus apparatus lateralis ? Paris, 1744.— (b) Chelius, Ueber den Steinschnitt beim in Halleri Disput. Chirurg., vol. iv., p. 208. Weibe; in Hcidelb. Klinisch. Annalen, vol. (d) Above cited, vol: ii, p. 279. vi. part i. Sichereu ; in Wurtembergischen (e) Mery, Observations sur la Maniere Correspondenzblatt, July, 1*43. No.22. de tailler les Deux Sexes pour TExtraction {c) An educendo.oalculo casteris antefer- de la Pierre, pratique© par Frere Jacques. Paris, 1-7U0. 352 CUTTING FOR THE STONE IN WOMEN, vagina downwards. The operator, after having assured himself of the position of the pubic bones, and of any variety of the pudic artery, by the introduction of his finger into the vagina, places the left fore and middle finger upon the points where the cut is to begin and end, and with them stretches the cellular tissue. Then holding a straight bistoury, as a pen, he makes a semi-circular cut through the external membrane, and the stretched cellular tissue of the vestibule, which is to begin on the right side at correspondent height with the orifice of the urethra, runs within the pubic arch at the distance of a line, and terminates on the left side at a similar height to its beginning. The cellular tissue is then divided layer by layer in the same direction till the front of the bladder is cut through, in doing which all pressure against the bladder must be avoided. The left thumb is now introduced into the vagina, and the left forefinger into the wound, and the wall of the bladder therewith made tense and pressed forwards. A longitudinal or transverse cut is now made into the body of the bladder with the bistoury, or if this seem to be unsafe, the cut is to made on the groove of the staff, or a dart sound may be used^ upon which the bladder is opened, and the fore- finger being passed into the wound, it is to be enlarged either lon- gitudinally or transversely with the knife (a). 2129. This proceeding of Lisfranc's is objectionable on very many grounds. The cut is-made into the bladder where there is least space, consequently the extraction of even a moderately large stone is difficult, and accompanied with bruising; the pudic artery, the position of which cannot be well determined by the examination before the operation, may be wounded; the front of the bladder is easily separated from its cellular connexions; the vascular net at the seat of the cut, often much developed in stone-patients, may be injured, and the wound in the bladder may slip from the external wound, in consequence of which there will be infiltration. It is difficult to understand how in using the dart sound, at least with its usual curve, the dart can be protruded some lines above the neck of the bladder {b). Piers Uso Walter (c) has practised Lisfranc's vestibular cut successfully in a woman of forty-five. 2130." von. Kern's practice, which he has successfully followed, is the following. After the patient has been properly placed and the staff in- troduced into the bladder, an assistant standing on the right side, holds the staff with his left hand and sinks it a little towards the patient's right groin, and-places thefore and middle fingers of the right hand near the orifice of the urethra at its under part, which he draws down tightly, at the same time separating the labia with the thumb and other fingers. The operator then, finds the hinder extremity of the urethra with the left thumb-nail near the neck of the bladder, places the nail upon the right edgeof the staff, penetrates the stretched urethra with the lithotome, and enlarges the Gut by carrying the scalpel forwards in the groove of (a) Memoire sur une Nouvelle Methode (ft) Baudrv, L., Dissert, du meilleur Pro- de pratiquer l'Operation de la Taille chez la cede a employer pour l'Operation de la Femme ; in Revue Medicale, vol.. x. p. 1. Taille chez la Femme. Strasb., 1823. 1883.—MeresseI Dissert, sur la Lithoto- (c) von Gkaefe und von Walter's naie, chez la Femme. Strasb., 1823. Journal, vol. xviii. p. 285. BY THE YAGINO-VESICAL CUT. 353 the staff, and at the same time presses it on with the thumb until the opening is of sufficient size (a). 2131. The vagino-vesical cut has the closest resemblance to the recto- vesical; it is performed most safely in the following manner. After placing the patient in the position for the lateral operation, a staff is passed by the urethra into the bladder, and a wooden gorget with its con- cavity upwards is introduced into the vagina. Both instruments are brought together so as to form a larger or smaller angle, in proportion to the cut to be made. Tb,e gorget is to be well pressed downwards, so that the front wall of the vagina can be got at. A straight, pointed bistoury is to be held like a pen in the right hand, its point passed into the groove of the staff behind the canal of the urethra, and then by thrusting it forwards, an opening is, made corresponding to the size of the stone. Its extraction and after-treatment are conducted according to-, the ordinary rules. 2132. The advantages of this mode of operating are great. There is no bleeding, no incontinence of urine, and the largest stone maybe in this way removed. The production of a vesico-vaginal fistula, which may be objected to this operation, cannot, at least from present experi- ence, be considered as the usual consequence. If this operation be restricted only to the extreme cases of very large stones, it has however there undoubted preference over cutting into the bladder above the pubes, as the patient's life is never endangered, and at the utmost there is the inconvenience of a fistula. The objection made by some, that the scar produced by this operation would cause difficulty in child-birth, is con- trary to experience. Upon this subject the following works may also be consulted:— Fabricius Hildanus, De Lithotomia, p. 149, Ruvsch, Observationes Anatomico-pathologicae, Obs. i. Mery, above cited, p. 28. Louis, above cited. Bussiere ; in Philosophical Transactions, vol. xxi. p. 100. 1699. Lister, Iter Parisianum, 1697. Gooch, Cases and Practical Remarks in Surgery, vol. ii. p. 182. London, 1758. 8vo. Michaelis, Etwas iiber den Blasenschnitt, p* 57. Marb., 1813. Dupuytren, above cited, p. 55. Flauber et Clemont ; in. Sanson, above cited, p. 23. Vacca Berlinghieri, above cited, p. 110. -------------------, Del Taglio vagino-vesicale, Pisa, 1825. [In all the previously described operations, incontinence of urine is a very trouble- some consequence and often incurable. Astley Cooper, indeed, says:—"In all cases of this operation which I have performed or'witnessed, the urine has not been afterwards retained ; but I would not deny that a patient might recover the retentive power. As the loss of retention is a greater evil than I can describe, producing excoriation and a very ofTensive state, I shall in any future operation of lithotomy, try what may be effected by employing a suture to bring the divided parts together." (p. 303.) Brodie's operation (par. 2124) seems to have been partially successful; but Liston (par. 2123) seems to think that his mode causes only a temporary in- continence. Most surgeons however are, I believe, sadly perplexed with this tire- some result, and the patient necessarily still more so. Very recently I have seen a woman, who was cut with the gorget about twenty years ago; she cannot retain her water at all, but it is constantly dribbling away, and she is in a very pitiable con- fa) Above cited, p. 154, 354 COMPARISON OF dition. To avoid this untoward result, Hey (a) made use of a cylindrical linen tent two inches long and one broad, which he passed into the vagina, for the purpose of bringing the edges of the wound together without obstructing the urethra, and the plan succeeded. Brodie tried the same method, but unsuccessfully; though per- haps it may have depended on the child's irritability. I am not aware that Astley Cooper's suggestion of sutures has yet been tried. The large size of stones which have been passed spontaneously, as related by Heister (b), Middleton (c), Colot, (d), Molineux (e), and Yelloly (/), as well as the earpicker-case mentioned by Thomas (g), which was removed by dilating the urethra with sponge tent, led to the proposal of dilating the urethra either with sponge, or with an instrument corresponding in form to a speculum ani. These methods have, however, been generally followed by incontinence, if the dilatation have been made to any great extent. Brodie says, indeed, that " none" of the Cases to which he refers "suffered from actual incontinence of urine; but one of them, in whom the calculus was of large size, could not retain more than two or three ounces of urine in the bladder afterwards." And hence he concludes, that "the method of dilatation is not to be recommended, except in cases of moderate size." (pp. 351, 52.) I think, if I should be called on to operate for stone in the female, I should be disposed to perform the lateral cut with the gorget or knife, it would not matter much which, and adopt the method recommended by Hey.—j. v. s.] 2133. Opening the bladder above the pubic symphysis has been particu- larly recommended in women, because, in drawing out the stone by the outlet of the pelvis, injury of the vagina or of the pudic artery is feared ; large stones cannot at all be extracted, and incurable incontinence of urine remains as the frequent consequence of this operation. The pro- ceeding is conducted exactly as in the male, and the escape of the urine from the wound above can be more readily prevented, by the introduc- tion of a catheter through the urethra. COMPARISON OF LITHOTOMY AND LITHOTRITY. 2134. In considering the advantages and disadvantages of lithotrity, as compared with those of lithotomy, it must be first remarked, that many of the objections properly made to its earlier mode of performance, as the difficulty of introducing the instruments, its tedious operation, especially when the stone is hard and the like, have lost much of their importance, or are entirely removed, by the great degree of perfection to which lithotrity has of late attained. The time has not, however, yet fully arrived, nor are the results yet in such condition, that a positive opinion can be given on this point. The hitherto-furnished statistics of the results of lithotomy and lithotrity afford no decisive clue, because stone-patients must, in reference to this point, be divided into three classes; first, those which are favourable, for the effectual crushing; second, those in which the crushing may be attempted, but cannot be completed; third, those in which, on account of various circumstances, lithotrity must from the first be considered inapplicable. It is therefore (a) Practical Observations on Surgery, p. (d) Traite de 1' Operation de la Taille. 560. Edition of 1810. Paris, 1727, 8vo. (6) Chirurgie. Niirnberg, 1719.—Trans- (e) Philosophical Transactions, vol. xx. p. lated as, A General System of Surgery. 11. 1698. London, 1757. Sixth Edition. (/) Med.-Chir. Trans., vol. vi. p. 577. (c) A Short Essay on Lithotomy above (g) Ibid., vol. i. p. 123. the Pubes. London, 1727. 4to. LITHOTRITY AND LITHOTOMY. 355 clear that if only simple and slight cases fall within the compass of lithotrity, and that to lithotomy the other two unfavourable classes belong, therefrom the results of both must necessarily be judged. In the collation pf such results, in great number and for a length of time, the progressive improvements in the operations of lithotomy and lithotrity must be also well considered. Only in reference to these different circumstances can it be comprehended, how the results which have been collected from a great number of cases of lithotomy, have been more favourable than those of lithotrity (perforation); and how the results of percussion, (Heurteloup,) though by far more favourable than those exhibited by the earlier ones of perforation, and of cutting, have nevertheless been surpassed by the results which individual operators have obtained with the knife. 2135. If the possible evils which may occur in and after lithotomy and lithotrity be compared, they are found to have a certain degree of equality as to their number and danger; only that in lithotomy, the wound espe- cially gives rise to symptoms which in lithotrity are absent, whilst the latter occasions considerable irritation of the bladder, and dangerous symptoms resulting therefrom. The possible evils resulting from lithotomy are bleeding, wound of the rectum, of the seminal vesicles and their excretory ducts, and of the deep pelvic aponeurosis; subsequently, bleeding, infiltration of urine, extravasation into the scrotum, inflammation of the cellular tissue of the pelvic cavity, inflammation of the peritoneum, of the bladder, of the prostate and of the veins, urinary fistula, impotence, and incontinence of urine. The possible evils from lithotrity are violent pain and nervous symp* toms, especially in very sensitive persons, inflammation of the urinary passages, of the prostate, and of the testicle; in rare cases, tearing of the mucous membrane of the bladder, perforation of the bladder, inflamma- tion of the veins; further, retention of urine, infiltration of urine, urinary fistula, breaking of the instruments in the bladder (1), and recurrence of stone (2). [(1) In the event of lithotritie instruments being broken or bent in the bladder, so that they could not otherwise be removed, Liston says :—"I had determined, should I meet with any case of the kind, to pull forward the instrument as far as possible, so as to bring the sliding blade (of the percuteur) into close contact With the ante- rior walls of the bladder, and these with the anterior aspect of the symphysis, then to push down the penis upon its stalk, and protect the glans with a piece of split card or strong leather; the instrument was then to be seized with a hand-vice, and cut through as low as possible, by the use of good files; this can be done within two inches and a half of the curve. There would then be no difficulty in pushing the blades containing the stone back into the bladder and commencement of the urethra, and cutting them out together." (p. 502.) (2) "It may be said," observes Brodie, "that hemorrhage is one of the incon- veniences attendant on the operation of lithotrity. It may arise from the forcible introduction of the lithotrity-forceps through the hfeck of the bladder, where the prostate gland is somewhat enlarged, or from the dilatation of the prostate and urethra in the act of withdrawing the forceps, when the blades are charged with a conside- rable accumulation of the crushed calculus matteh The loss of blood, for the most part, does not amount to more than a few drops; but in some instances, I have known it to be sufficient to discolour the urine for one or two days afterwards. * * * The occurrence of rigours is another ill consequence of lithotrity, in some instances. I have already mentioned, that a rigour is usually produced by the stretching of the 356 COMPARISON OF urethra, at the time of the forceps being withdrawn from the bladder, and that, in most instances, it may be prevented by the exhibition of a dose of opium immedi- ately after the operation. This symptom, however, may arise from other causes; as, for example, from a fragment of calculus finding its way into the urethra, which is too large to be expelled by the pressure of the stream of urine. And it sometimes happens, that the effect of a dose of opium is, not to prevent the rigour altogether, but to cause it to be deferred till the following day. The liability to rigours, how- ever, where due precautions are used, is seldom such as to interfere in any great degree with the process necessary for the patient's cure and his ultimate recovery."— (pp. 370, 71.)] 2136. If these various circumstances in lithotomy and lithotrity be compared in regard to their cause, to wit, the wound in lithotomy, and the injury of the bladder in lithotrity, it must be presumed that pain and nervous symptoms may be equally present in both, but their frequent repetition in lithotrity is of importance; that bleeding, wound of the rectum, injury to the peritoneum, which are very much to be dreaded in lithotomy, cannot happen in the modern practice of lithotrity; that infil- tration of urine, so frequently fatal after lithotomy, is almost impossible in lithotrity; that phlebitis and peritonitis are observed not unfrequently after lithotomy, but very rarely after lithotrity, which also applies in like manner to the continuance of fistula; that, on the other hand, inflamma- tion of the bladder, inflammation and abscess of the prostate are more common after lithotrity than after lithotomy. Brdising or tearing of the mucous membrane of the bladder, as also breaking of the instruments in the bladder, is at the present time scarcely possible, with the improved instruments. Many of the evils mentioned are principally dependent on the operator; this remark, however, applies as well to lithotomy as lithotrity. 2137. Further, if lithotrity be considered in reference to the condition of the urinary organs, the age, sex, and constitution of the patient, and the nature of the stone, it follows, that a diseased change and swell- ing of the prostate, purulent catarrh, great sensibility, and contraction of the bladder, render lithotrity quite impossible, or considerably increase its danger. Although lithotrity was formerly considered inapplicable to children, and numerous experiments by Civiale, Amussat, Leroy, and others, have proved its practicability in little Children; yet, however, the result of lithotomy at this age is so favourable) and the employment of litho- trity so difficult, that lithotomy should undoubtedly be preferred. In advanced age, on the contrary, the results of lithotomy are far more un- favourable than those of lithotrity. In females, the less difficulty in the introduction of instruments (par. 20-57) is compensated by the diffi- culty of keeping the bladder distended; but lithotrity, although lithotomy in woman is much more rarely fatal than in man, has this great advan- tage, that no incontinence of urine remains after it, an infirmity, the im- portance of which in women cannot be too seriously thought of. It must finally be remembered * that for very stout persons, who are always the most unfavourable subjects for lithotomy, lithotrity is by far less dan- gerous. In reference to the nature! 6f the stone, it must also be considered, that with the improved new instruments, even large stones may be broken to pieces, and that no stone, from its hardness, can easily withstand their LITHOTOMY AND LITHOTRITY. 357 effect; but the frequent repetition of the operation, which in such cases is necessary, causes danger, partly from the frequent irritation of the urinary organs; partly, and especially, from the repeated febrile excitement, and the inflammation of other organs thereon dependent. The same also applies to stones in large number. Such stones as are of moderate size and round or oval form, are.best for crushing; flat stones are difficult to grasp and break up. 2138. If now, after the consideration, founded on experience, of the advantages and disadvantages of lithotomy and lithotrity, the particular cases in which the one or other practice is specially indicated, be re- viewed, it follows that lithotrity appears preferable, first, in small stones or those of no great size; second, when there are two, or several little stones; third, in stones of moderate size, and when they can be easily broken, and if in all these cases the bladder be healthy, or only in a trivial degree affected. These indications are more important, when such cases occur in old persons, in females, or in very stout people. On the other hand, lithotomy is decidedly to be preferred; first, in childhood ; second, with large and hard, and especially mulberry stones ; third, when there are several large stones; fourth, when large stones entirely fill, or are completely locked in by a contracted and unextensible bladder; fifth, in diseased prostate, or se-vere affection of the bladder; sixth, in very great sensibility of the bladder, so that the patient can bear neither its distention, nor the motion of the instruments; seventh, with stones, of which the nucleus, as, for example, when it is a bullet or the like, cannot be destroyed by the lithotriptor. It is also not to be overlooked, that in the general employment of lithotrity, the patient should be subjected to it early, by which its results are more certain, and its use will become more easy and general. On the other hand, however, it must not be unnoticed, that under directly the same circumstances, which are favourable for crushing, does cutting for the stone, if performed with ability, lose much of its danger. Strictures of the urethra are only temporary contraindications for lithotrity, and equally applying to lithotomy, they must be'first got rid of. Palsy of the bladder neither coniraindicates lithotrity, nor renders its performance difficult. Should the fragments of the stone indeed be discharged more slowly or with difficulty, this may be easily overcome by injections; and experience has shown that the palsy of the bladder has been relieved, and even removed, by the effect of the lithotriptic opera- tion, which, however, has also been several times noticed after lithotomy. [" Since commencing the practice of lithotrity, I have found," says Key, "that more than half the number of adults who have cOme under my care have been fit subjects for the operation ; and that in the majority of persons afflicted with calculus, it has decided advantages over lithotomy. One among the principal advantages which lithotrity has conferred on surgery, is the early application which patients are induced to make for the relief of their disorder. Formerly * * * the disease was associated in their minds with a most painful and dangerous operation, that must be had recourse to, asa last remedy, when palliative measures failed to afford Telief to their sufferings. The dangers and sufferings of lithotomy, magnified as they were by the patient's fears, often deterred him from applying for medical assistance when the pains of stone first came upon him, by the dread of having his worst fears con- firmed. Even if the presence of a stone in his bladder were ascertained, it was, in too many instances, allowed to remain undisturbed, in the vain expectation that it might not increase in size, and that the severity of pain might continue to be miti- gated by the medicines that so often had been found to assuage his pangs. The operation was thus procrastinated until the stone acquired a large size, often until trie bladder had become diseased, and the patient's health undermined by protracted Vol. iii.—31 358 COMPARISON OF sufferings. * * * Nor has lithotrity been without its influence on the surgeon. Formerly, when a patient first consulted him for symptoms of dysuria, followed by pain, he was content to palliate the malady by sedative and alkaline medicines, re- gardless whether they were caused by prostatic affection, stone, or any other local disturbance. The use of the sound was deferred : that could be used at any time: and, usually, it was first introduced into the bladder when the patient's sufferings had become severe and protracted. * * * The operation of sounding was also con- ducted in a slovenly manner. If the stone were not discovered when small, it would be when large, and no advantage was gained by operating in the early stage. Now, the surgeon examines the bladder with great care, knowing the importance of dis- covering the calculus at the earliest perind, he no longer leaves its existence a matter of doubt, but proceeds at once to examine the bladder, and determines its presence; or by a skilful searching of every part of the viscus, ascertains that a stone does not exist. * * * The early symptoms of the disease are thus watched with more jealousy on the part of the surgeon, and are not so scrupulously concealed by the patient. The advantages of an early knowledge of the existence of a stone, and of prompt measures for its removal, are known to both. The result of this is, that patients apply for advice when the stone is small, the bladder uninjured by its pre- sence, and the kidneys free from disease. In three out of four persons who apply for advice, for symptoms of calculus, the size of the stone and the conditions of the viscus render lithotrity an easy and safe operation. Within the last three or four years, I have marked the very early application that patients make for advice, and the small size of the stone when first discovered, compared with those of former years. In private practice, I have not extracted, by either operation, a calculus larger than a good-sized mulberry, except in three cases, in one of which the stone was of un- usually rapid formation." (p. 13-16.) " The size of the calculus," observes Key, " forms of itself no objection to litho- trity. A large stone presents, however, several considerations for the surgeon^'to weigh before he undertakes the operation. As the stone cannot be entirely crushed at one sitting, a patient with an irritable or unsound bladder, becomes involved in most serious danger by the operation being hastily adopted. A large stone broken up into many irregular fragments, all crowded by the contractions of the bladder against the irritable and inflamed cervix, causes excessive efforts to void the urine, and even inflammation of the mucous surface. Under such circumstances, the re- petition of the operation becomes impossible, or highly dangerous; and the patient has to struggle through the stages of inflammation, with a bladder irritated by the lesser fragments. But if the bladder be free from disease, and not very irritable, it will bear the number of sittings required to break up a large stone, without much suf- fering to the patient, and with very little danger. The success of lithotrity, like that of most surgical operations mainly depends on its subject. If the constitution be good, and the power of endurance great, difficulties of most unpromising nature may.be overcome. We should therefore pay more regard to the general condition of the patient, and of his bladder, than to the size of the stones; and inquire minutely into the several circumstances likely to have an influence on the result of the opera- tion. * * * I know of no limits to the size of a calculus removeable by lithotrity but the power of the lithotrite. If a powerful instrument can be brought to embrace it, and the organ be healthy, the operation may, as far as my experience goes, be at- tempted with propriety. " The differentnges of patients to be submitted to the lithotrite or the knife, are remarkably contrasted with one another. Whilst to youth and advanced age the latter is more suitable, the former is found generally better adapted to the middle period, between puberty and the decline of life. We have seen, in speaking of lithotomy, that persons whose sexual organs are completely developed, are .more liable to the accidents attending the use of the knife than children, whose organs are not yet evolved ; or than the aged, whose irritability is on the wane. The lull- grown healthy adult, on the contrary, presents all the conditions most favourable for crushing the calculus. The canal is sufficiently large to admit an instrument efficient from its size; the prostate gland is usually healthy, and free from the enlarge- ment of age ; thus rendering the neck of the bladder a part so important in the ope- ration, little exposed to the dangers of inflammation. When there is a normal pros- tate gland, the operator may manipulate his instrument without risk of bruising, or otherwise injuring this most sensitive of all the parts concerned in the operation. LITHOTOMY AND LITHOTRITY. 359 The urethra of such patients being more free, the fragments are expelled with less difficulty, and cause less pain in their expulsion, which is also materially assisted by a sound and vigorous bladder. At this age also, inflammation, should it super- vene, is more easily controlled than in the aged subject, who cannot well bear de- pletion. The warm bath and free venesection, speedily arrest the inflammation, of the mucous membrane of the bladder; but the old are soon depressed by the dis- eased action, as well as by the measures required for its suppression. Inflammation, however, is less liable to occur in such healthy subjects, where the parts are not mechanically injured by the operation, and when the patient has been prepared by dietetic and other prudential measures. The aged subject, however, is not less adapted to the operation than the younger adults, if he be free from the common accidents of age, as an enlarged prostate, accompanied with an irritable state of the bladder. If the parts in the aged are sound, the operation is especially successful in them; as there is less irritability in the organs of generation, and less excitability of the general system. The ur&thra also is usually larger, and if the neck of the bladder be free, it allows fragments of extraordinary size to pass. * * * In the old subject, however, difficulties often present themselves, in consequence of the change which the parts about the neck of the bladder undergo, and the unsound condition of the bladder itself consequent on these changes. The operation in such persons is rendered dangerous by the inflammatory disposition of the organ, and by the diffi- culty with which the fragments make their way through the prostatic portion of the canal. " The state of the bladder is, perhaps of all the circumstances that the lithotritist has to consider, the most important; and one on which the propriety of performing the operation will mainly hinge. Three conditions of this organ are necessary, and these must be ascertained by preliminary observations and trials, before the operation is de- termined on : first, it must be capable of holding a sufficient quantity of water to facilitate the working of the percussor; second, it must be free from that extreme irritability that often attends the latter stages of calculous disorders; and, third, not prone to inflammation from slight excitement. In healthy persons, the bladder, even under the irritation of a stone, will allow several ounces of water to be injected into its cavity, without sustaining more thana slight inclination to eject it. Its retentive powers are not impaired in the early stages of the disorder; patients will go for many hours without any desire to empty the bladder, the only early symptom being a smarting, when the bladder contracts on the calculus. It is therefore rare to meet with any difficulty in injecting water sufficient for the purpose of giving space for the operation, amongst those who apply for advice soon after the symptoms have begun to declare themselves. Even when, from the long-continued presence of the stone, the bladder becomes morbidly affected, and able to contain but three or four ounces of urine without an irresistible desire to expel it, much may be done by treat- ment to assuage the irritation of the mucous membrane, and tranquillize the muscu- lar excitability. When the stone has been long resident in the bladder, and has produced a change in the mucous membrane, and a copious discharge of phosphatic mucus, signs of extreme irritability come on, and almost seem-to forbid any expecta- tion of lithotrity being practicable. The desire to void urine is renewed every two hours or oftener; the urine not only deposits a large quantity of dark-coloured mucus but is cloudy, and loaded with small flakes of adhesive matter, the result of inflam- mation of the mucous lining; the pain in expelling the last few drops of mucus is intense. Such continued suffering affects the general health; and would seem, I say, to forbid the operation altogether. Frequently, however, will these formidable symptoms yield to a system of diet and medicine, and the patient by degrees be un- expectedly brought into a condition to bear-the operation." (p. 23-36.) "Those who have irritable bladders usually experience some form of irritation after moderate distention with water and examination with the catheter. It gene- rally assumes the form of rigour, occurring once or more in the twenty-four hours after the examination has been made, and followed by severe pyrexia, that lasts for several days. The rigour of itself indicates the degree of irritation produced by the sound ; and if not followed by the hot stage of fever, it indicates nothing more; but the presence of pyrexia is evidence of inflammation taking place, and such a state is most unfavourable to lithotrity. A distinction, therefore, is to be drawn between these two states ; the occurrence of a rigour need not deter the surgeon from com- mencing the operation—it often attends the first examination, and may never recur» 360 COMPARISON OF but the indication of inflammation, drawn from a continued state of pyrexia, should at once induce him to defer the'operation, until by withdrawing all stimuli, he has brought the bladder into a tranquil state. The disposition to inflammation is often kept up by improper food, especially drink; and is indicated by a plethoric condi- tion of the system, and a flushed countenance. Sueh a condition maybe overcome; arid is unlike that state of bladder which is the effect of commencing disorganiza- tion, and often associated with diseased kidneys, (p. 37.) "One principal source of irritability of the bladder is a morbid condition of the cervix, or of the prostate gland. The structure about ihe neck of the bladder, above all others deserves the especial attention of the lithotritist; as it is here that he will ever meet with the most difficulties, and will also find the chief source of danger. The extreme susceptibility of this part of the bladder is not unfrequently evinced in severe rigour and inflammation following the introduction of a sound in patients who complain of dysuria connected with an enlarged prostate. These persons, often highly disposed to inflammation, have a severe attack brought on by the casual introduction of an instrument for the purpose of ascertaining the eause of their ail- ments. When the morbid condition of the gland is combined with calculus, the risk of inflammation, and the danger of its consequences, become greatly increased; and the hasty performance of lithotrity in persons not prepared for the operation, has been known to induce a fatal cystitis." (pp. 38, 9.) "It would be a great error," says Brodie (a), " to represent lithotrity as prefera- ble on all occasions to lithotomy; but it is so in a great many instances. I shall endeavour to explain by what signs you may distinguish from each other the cases to whieh it is applicable, and those to whieh it is not. In boys under the age of puberty, lithotomy is so simple and so generally successful, that we ought to hesi- tate before we abandon it for any other kind of operation. There is also a manifest objection to lithotrity in these cases, on account of the small size of the urethra, which is such that it would not admit of the introduction of instruments of sufficient strength to crush a calculus of more than moderate dimensions. In the female sex the extraction of a calculus from the bladder by the ordinary methods is attended with little danger; while the operation of crushing is rendered difficult inconse- quence of the short and wide urethra, allowing the water which has been injected into the bladder to escape by the side of the lithotrity-forceps before the operation is completed. In cases in which the calculus has attained a very large size, it is often difficult to seize- it with the lithotrity-forceps ; the operation of crushing requires to be repeated a great number of times, so that many weeks may elapse before the cure is accomplished ; a large quantity of fragments is left in the bladder, of which the necessary consequence is a great liability to inflammation of the mucous mem- brane; and of course the inconvenience produced by the passage of the fragments along the urethra is multiplied, as compared with what happens when the calculus \s smaller. These circumstances form a sufficient objection to the operation of litho- trity in these cases. It is true that they are unfavourable cases for lithotomy also; but I have little doubt that the latter method is the safer of the two. It admits of a question, whether in such cases the two modes of operating may not be advantage- ously combined, the calculus being crushed into three or four pieces first, and ex- tracted by the usual incision afterwards. The operation of lithotrity is not well adapted to those cases of enlargement of the prostate gland, in which the patient is unable to empty the bladder by his own efforts, unless the calculus be of small size, so that there may be no difficulty in crushing the minute fragments into which it has been crushed out of the bladder through a large catheter. There is also another objection to the operation in some cases of enlargement of the prostate, namely, that the tumour which projects from it into the cavity of the bladder, makes it difficult to elevate the handle of the forceps sufficiently to seize the stone easily in the usual manner. "I have described the dangers which attend on lithotomy in those cases in which a calculus of the bladder is complicated with disease of the kidney. One of the principal of these is connected with the loss of blood, which that operation must always occasion to some extent, and not (infrequently to a great extent, in spite of the best exertions of the surgeon to prevent it. I have no doubt that in such cases, the operation of crushing is the safest method of proceeding; but a small shock to (a) Above cited. LITHOTOMY AND LITHOTRITY. 361 the system will sometimes destroy the life of a patient who labours under renal dis- ease, and it will be often more prudent to trust to the means which we possess of palliating his sufferings, than to run the risk of shortening his life in the endeavour to obtain a cure. * * * With the exception of such cases as those which have been enumerated, there are few to which this method of treatment (Lithotrity) may not be advantageously applied. It may be said that the exceptions are numerous ; but they are the result chiefly of delay. If a patient seeks the assistance of a com- petent surgeon within six or even twelve months after a calculus has descended from the kidney into the bladder, the urine having remained acid, it will rarely happen that he may not obtain a cure by a single operation, and with so small an amount of danger, that it need scarcely enter into his calculations. As time advances, the facility with which he can be relieved diminishes, and after the lapse of two or three years, especially if the urine has become alkaline, it is probable that the calculus will have attained such a size as to render the old operation (Lithotomy) preferable, and that the access of disease in the bladder or kidneys may render any operation hazardous. It would be absurd to say, and it would be unreasonable of humankind to expect, that an operation which has for its object to relieve them of a disease so terrible as that of a stone in the bladder, can be always free from inconvenience, and difficulty, and danger. Nevertheless, from what experience I have had, I am satis- fied that the operation of lithotrity, if had recourse to only in proper cases, is not only much more successful than that of lithotomy, but that it is liable to fewer ob- jections than almost any other of the principal operations of Surgery." (p. 375-79). "The operation of lithotrity," says Liston (a), " is applicable to patients above the age of puberty, when the symptoms have not endured very long; when the foreign body is ascertained to measure six or seven lines, or even more perhaps, say as large as a,chestnut; when the bladder and urethra are in a tolerably healthy and normal condition,—as indicated by the power to retain the urine comfortably for several hours, and to pass it in a tolerably free stream; and when the viscus admits of injection and a careful exploration. That the stone may be seized readily, and acted upon without danger to the lining membrane, the bladder should contain at least five or six ounces of fluid, (pp. 500, 501.) " When the stone is much larger than above indicated, and when there is reason to suspect that the bladder, in consequence of the endurance of the irritation, has become contracted, fasciculated and irregular on the surface, presentingthe rudiments of pouches, it will be absolutely impossible to make sure of removingall the detritus. Nuclei must be left, and very shortly the patient will have five or six stones perhaps substituted for the original one formed upon these. The suffering and danger, more- over, endured by the patient at each sitting, when these are often repeated', in an unsound bladder, for removal of the fragments of a large concretion, are much greater than those resulting from a speedy and well-conducted safe operation for its removal entire and at once. When lithotomy is well performed,'the excited state of the bladder is relieved by the removal of all source of irritation, by the viscus being put at rest, and its functions suspended, and by the loss of blood from the neighbouring vessels. In lithotrity, on the other hand, when the stone is large, considerable fragments are often left, and the irritation is thus greatly increased. The pain experienced in passing fragments, is often extreme, and not unattended wiuYdanger; for difficulty is often experienced in dislodging portions from the urethra. Then retention follows, perhaps, with inflammation of the bladder. * * * Blood too is often lodged in the bladder and removed with difficulty. The excited action which follows is perhaps at first slow and weak, but it soon becomes lighted up by the continued irritation resulting from the frequent contraction of the viscus, and contact with the angular pieces of the concretion. Unless a very correct judgment is exercised in determining upon the practice in particular cases, and great gentleness observed in the manipulations, fatal results must very often follow. "The operation of lithotomy must jet continue to be performed on children, and on those of mature age who are so ill informed or foolish as to permit the stone to attain an inordinate bulk. * * * Of late years, in point of fact, I have scarcely been obliged to have recourse to lithotomy at all in private practice. At the hospital, patients yet present themselves with large stones and bad bladders. Then lithotomy (a) Practical Surgery. 31* 362 STONE IN THE URETHRA. is both a less painful and much more safe operation, as already propounded. During the period of the last six years, twenty-four patients have been cut, and all have recovered without accident; these patients have been of all ages, from two to eighty years, and some of them not over favourable subjects. So that, after all, there is not much to find fault with as regards this ' cruel and bloody operation,' when care- fully set about." (p. 503-505.) I do not propose to offer any opinion of my own as to the preference which should he awarded to lithotrity, or lithotomy, as I have had little practical experience in regard to the former, and am not therefore qualified to give one. But I may he per- mitted to say that the results of the practice of lithotomy, both with gorget and knife, and by various operators on patients of all ages and under various circumstances, during the course of a long series of years at our Hospital, have been so favourable, as to afford little cause for making it give place to lithotrity. I think it is proved that lithotomy, when properly conducted, is not the dangerous operation it is too commonly held to be; and it is no trifling advantage it possesses, that the patient is relieved at once, with a few minutes' suffering, sharp indeed it must be acknow- ledged to be, instead of being subjected to several operations, which, the more fre- quent in their repetition, become, as generally admitted, greater in severity, and occasionally leave the necessity for resorting to the cure by lithotomy. I may also here add the testimony of some patients who have undergone both operations, that the suffering during lithotomy was less than in lithotrity, and that knowing both, they would, if needful,, prefer undergoing the former. It is well, however, that we have the opportunity of employing lithotrity in cases where patients are too fearful to submit to the knife; but I am by no means sure that under all circumstances, lithotomy is not at least as free from danger as lithotrity, and certainly more speedy as regards the cure.—j. f. s.] Upon the relations of lithotrity'to lithotomy, the following writers may also be consulted:— Blandin. Velpeau in Doubovitzkt. Wattmann. Hecker. Longhi, A., Sulla Cistotomia e Litotrizia. Pavia, 1839. King, Thomas, M.D., Lithotrity and Lithotomy compared. London, 1832. 8vo. V.—PF STONE IN THE URETHRA. (Calculus Urethralis, Lat.-; Steine in der Harnrbhre, Germ.; Calcul dans le Canal de VUre.tre, Fr.) 2139. Stones which enter the canal of the urethra, as well as foreign bodies which have been introduced from without, may be fixed at different parts, may more or less hinder, or entirely prevent (1), the flow of urine, and cause inflammation of the urethra and of the whole penis, ulceration, and gangrene of the urethra, urinary infiltrations, fistulas, and the like. If the stone or foreign body be angular or pointed, the earlier will these symptoms be produced (2). [(1) A stone may sometimes exist for some time in the urethra, and prevent the flow of urine by the stream forcing it tightly into the front of that canal, which is too narrow to permit its escape. An instance of this kind occurred to Travers in 1829, in a man of sixty years, under his care in St. Thomas's Hospital;"he had been in the habit of passing small stones from childhood, during which he had been cut by the elder Cline for stone in the bladder, and, when fifteen years old, a stone block- ing up the urethra, immediately in front of the scrotum, had been out upon and removed, but left a fistulous aperture. When he came under Travers's care, he had a sto/ie about, four inches down the urethra, and this, when desirous of making water, he pushed back towards the fistulous opening, so that there was then room for STONE IN THE URETHRA. 363 its passage. At night his urine constantly dribbled away. This stone was removed by cutting through the fistula into the urethra, and lifting it out with a scoop. The aperture, however, did not perfectly heal (a). A good example of retention and consequent mortification from the complete blocking up of the urethra by a stone, is Everard Home's case in the College Col- lection (b), of two stones from a man of sixty years old :—" The large calculus was situated in the membranous part of the urethra, the smaller about three inches from the external orifice, the urethra being dilated into a cyst at each of these parts. The patient supposed himself to have laboured under strictures of the urethra for ten years! at last there was complete retention of urine; the urine became effused behind the smaller calculus, and mortification of the skin of the penis and scrotum took place to considerable extent, and the man died." (p. 121.) (2) A curious instance is recorded byLiSTON(c), of a person who, "when a boy, had pushed a small brass curtain-ring over the penis till stopped by the scrotum, in order to prevent the urine passing off during the night. The swelling that ensued prevented its removal; he kept the occurrence secret; the tumefaction gradually abated, and the ring disappeared. But the hardened mass which remained increased in size; and latterly the functions of the parts, which had previously been very well performed, began to be disturbed. The foreign body was cut upon and removed," by Liston, " when the man was approaching fifty years of age." On making a section of it, the greater part of the ring was found forming the nucleus. The con- tinuity of the erectile tissue, which had been cut through gradually by the foreign body, was perfectly re-established." (p. 520.)] 2140, If the stone lodged in the neck of the bladder, it will, if small, produce only the common symptoms of stone in the bladder, but if it be large, it will cause more or less complete retention, and if angular and not completely enclosed by the neck of the bladder, incontinence of urine. The patient usually suffers urgent pain, a sensation of weight and pressure in the perineum and rectum, and a constant burning in the urethra, especially at the glans. A stone of any considerable size may be distinguished by the ringer in the rectum, but most certainly by a metallic sound introduced into the urethra, which is either stopped by the stone, or passes near it into the bladder. 2141. If it be not possible, after the previous enlargement of the urethra with large bougies passed down to the stone, to grasp it with Hunter's or Cooper's forceps, or Civiale's instrument, in doing which, the introduction of one or two fingers into the rectum, so as to press against the stone, prevents its being pushed back into the bladder, and then extract or thrust it back into the bladder, {par. 2052,) it must be removed by a cut. . If a staff can be introduced close to the stone, into the bladder, a cut must then be made, as in the lateral operation, into the prostate and part of the neck of the bladder, its situation ascertained by the finger, and the size of the cut increased as may be necessary. The staff must now be removed, and with the finger passed into the rectum, it must be attempted to press the stone out, or at least prevent it getting back into the bladder, so that it may be removed with the forceps, or with a scoop. If the staff cannot be passed into the bladder, it must be carried down to the stone, the membranous part of the urethra opened upon it, and a director tried to be passed into the bladder, upon which its neck is to be sufficiently cut into. If the staff cannot be introduced into the bladder, its neck must be divided up to the stone, which must be pressed up from the rectum, and even cut upon. After the removal of the stone, the finger or the sound should always be passed into the (a) Clark's Case Book. (b) Taylor's Catalogue. (c) Practical Surgery. 364 STONE IN THE URETHRA ; TREATMENT. neck and body of the bladder, to ascertain whether there be any stones remaining. If, during the examination with the sound, the stone be forced back into the blad- der, it must be crushed. [When a stone is found lodged in the urethra, and more especially if it be far down that canal, the greatest care must be taken that it be neither pushed back by the sound, nor allowed to slip back in the handling; as if this happen, it will be ne- cessary either to cut into the bladder, or to attempt crushing, as Chelius recom- mends, which places the patient unnecessarily in a very unsatisfactory condition.— j. f. s.] 2142. If the stone lodge in the membranous part of the urethra, it may increase on account of the yielding of the urethral wall, and easily destroy it by ulceration and fistulous openings. If the stone cannot be removed by the use of lukewarm baths, by the gradual enlargement of the urethra with bougies, by gentle pressure, or by the already-mentioned forceps, it must be taken out by a cut, in which case the stone should be pressed against the perineum by the finger in the rectum, and then cut upon in an oblique direction, from the raphe to the ischial tuberosity. After the removal of the stone, a thick elastic catheter should be intro- duced into the bladder and the wound closed with sticking plaster. 2143. If the stone be situated in the spongy part of the urethra, it may most commonly be got rid of by the use of soothing baths, by the enlargement of the urethra, by pressing it forwards, or by means of the forceps already mentioned, or by a loop'of wire. If these means be in- effectual, or the symptoms urgent, a cut must be made on the stone, which should be fixed with the fingers of the left hand, and then pulled out; after which a catheter is to be introduced, and the wound carefully closed. If the stone have been long retained,^and the walls of the urethra be much distended and changed, an incurable fistula very easily occurs. If the cut be requisite in the region of the scrotum, which should be carefully avoided for fear of urinary infiltration, it must be made through the skin made tight, but not dragged out of place, sufficiently behind, and care taken for the due passage of the urine by the inlying of a catheter. 2144. If the stone be stopped in the fossa navicularis, and cannot be removed on account of the narrowness of the orifice of the urethra, the orifice must be slit towards the frenum. In rare cases the whole urethra has been so filled with stones to its mouth, that even the smallest sound could not be introduced. Under these circumstances the urethra must be opened at several parts, and if vesical stones be present, a cut made even into the bladder itself (a). [If a stone be any where in front of the scrotum, it can most commonly, and should be extracted without cutting; for, as Liston very justly observes, "owing to the thinness of the coverings, it will be found a most difficult matter to close entirely any opening anterior to the scrotum." (p. 520.) I have frequently succeeded, by following the advice of the younger Cline, in getting out a stone so lodged, though at first the attempt seemed very unpromising, by a very simple contrivance, but persevejred in with patience. This consists, in first nipping the urethra tightly be- hind the stone, so as to prevent it slipping backwards, and then introducing an eyed probe, with its eyed end a little bent, so as to form a sort of spoon or loop; it is to be gently insinuated between the wall of the urethra and the stone, till its point have got completely behind the latter. Then pressing the stone forwards with the thumb and finger, which grasps the urethra, the probe is gently and by little jerks (a) Klein, in Neuen Chiron., vol. i. p. 78. URINARY STONES EXTERNAL TO THE URINARY PASSAGE. 365 to be drawn forwards, bringing with it the stone, which is to be closely followed with the thumb and finger of the other hand. By thus proceeding with patience, the stone is after some time brought up to the glans, and if the lips of the urethra be there too narrow to allow its passage, the urethra may be cut through by the side of the fraenum with a lancet, and the stone is immediately set free. Should I meet with a case of this kind in which I was foiled, I am inclined to think that, rather than cut on the stone from without, I should pass a phimosis-knife down the urethra to the stone, and cut through its lining membrane into the spongy body of the penis sufficiently to enable the stone to move forwards, running the risk of infiltration of urine, which I should not much dread, by passing a catheter occa- sionally during the day to draw off the urine, or leaving it in, so that the water might flow away constantly. If infiltration did not ensue, there would probably be some temporary narrowing of the urethra, which might be cured by perseverance in the use of bougies. Any thing is better than an urinary fistula, which becomes the more serious in proportion as the urethra is opened near the front of the scrotum, in consequence of the readiness with which the urine will escape into the loose cellu- lar tissue of that part, causing troublesome abscesses and even gangrene.—j. f. s.] [Dickson, On Urethrotomy in the N. Y. Journ. of Med. and Surg. No. 7.—g. w. N.] VI.—OF URINARY STONES EXTERNAL TO THE URINARY PASSAGE.- 2145., Stones which are found external to the urethra, in the neigh- bouring cellular tissue of the perineum, {perineal stones,) or in the scro- tum, {scrotal stones,) are either such as have been deposited in the cel- lular tissue by the destruction of the walls of the urethra, and have grown by the continual deposition of the phosphates, or have been produced by the penetration of the urine into clefts of the urethra, into fistulas, wounds, and the like, into the cellular tissue itself. If the urine penetrate into several spaces of the cellular tissue, several stones may be formed at the same time. Such stones are easily distinguished by hard, nearly pain- less, frequently very large, swelling; often by the introduction of a sound into the urethra, when they partially project into it. They frequently cause suppuration and fistulous passages, through which a metal sound easily finds the stone. They are not rarely discharged by suppuration, in consequence of which incurable fistulas remain, if the wall of the urethra have been destroyed to any great extent (1). By the destruction of the walls of the vagina in women, and of the rectum in men, vesical stones may lodge in these cavities and be discharged. [(1) A very remarkable instance of a large collection of perinseal stones occurred to Vincent (a) in St. Bartholomew's Hospital in 1843. A young man, twenty- three years of age, suffered from incontinence of urine during the ten previous years, in consequence of having received at that time a kick on the penis from a horse; for this he had constantly worn a yoke. Four years after he had bleeding from the urethra, which was followed by a swelling behind the scrotum, and this, at the pe- riod of his admission, had acquired the size of a goose's egg. Upon this Vincent cut, "and gave exit to a hundred and forty-six calculi of various figures and sizes, the largest being about the size of a horse bean. After the pouch had been emptied, there were several in that part of the urethra next the bladder which were removed, and two of the number came away the next day. The cyst consisted of a dense and tough membrane like pa'rchment. It communicated with the urethra its whole length, and graduated into it, so as to offer no abrupt nor partial connexion with it, and appeared to be formed by its dilatation. After the operation the patient retained his urine, passing it voluntarily through the wound.' The stones consist of the fusible compound mixed with thin alternate layers of urate of ammonia, which are (a) Taylor's Catalogue of Calculi, above quoted. Appendix. 366 PROSTATAL stones. more abundant at the centre of each calculus; the urate, however, does not constitute a distinct nucleus." (pp. 137, 138.) In the College Collection there is also another very curious case of Vincent's:— " Numerous small calculi, which with about two hundred others, were removed from between the prepuce and glans penis of a very old man. The patient had congenital phimosis, the orifice of the urethra scarcely admitting the introduction of a common probe. From the presence of the calculi, the prepuce was distended to the size of a large pullet's egg, and retention of urine was finally produced. On dividing the prepuce, one of the calculi was found completely blocking up the orifice of the urethra. The glans penis was in a state of ulceration, and a large portion of its sub- stance had been absorbed. The patient had, during many years, occasionally expe- rienced great pain and difficulty in making water, and laterally he had a constant stillicidium. The calculi are composed principally of the fusible compound ; most of them have a small nucleus of uric acid ; their external surface is varnished oyer with urate of ammonia. From the composition of the nucleus, there can be no doubt but that the greater number of these calculi had passed from the urethra into the sac of the prepuce; and their irregular form and close adaptation to each.other, proves that in this situation they had increased considerably in size by the deposition of the earthy phosphates." (pp. 39, 40.)] 2146. These stones may be removed by sufficiently cutting on the parts containing them ; and if the stone be in the perineum and deeply lodged, attempts should be made from the rectum to press it through. If the cavity in wdiich the stone lies, be very large and hardened, it may be advisable to remove part of its walls. The after-treatment must be conducted according to the rules laid down for urinary fistula. Further notice of this subject may be found in Louis, Memoire sur les Pierres hors des voies naturelles de l'urine; in Mem. de l'Acad. de Chirurg., vol. iii. p. 332. Ilse ; in Medical Observations and Inquiries, vol. v. p. 336. Walther; in Salzburg Med.-Chir. Zeitung, vol. ii. p. 253. 1812. Klein ; in neuen Chiron, vol. i. p. 16. Graefe, Ueber Scrotal-Steine; in his Journal fiir Chirurgie und Augenheilkunde, vol. iii. pt. iii. p. 400—pt. iv. p. 695. Chelius, Ueber Scrotal-Steine; in Heidelb. Med. Annalen, vol. i. pt. i. [VII.—OF PROSTATAL STONES. Stone is occasionally formed in the prostate gland. This, " though not of urinary origin," remarks Prout {a), " is very liable to be mistaken for such, from the situation in which it is formed. Of this there seems to be two varieties. The first variety is usually formed in the natural cavities of the gland before it becomes much disorganized. They are generally small, and more or less rounded in shape, and of a yellowish- brown colour. The second variety seems' to be generally found in abscesses of that gland, where they are sometimes met with in great numbers. These are usually of much larger size than the first variety, and have a highly polished porcelainous appearance. The composition, how- ever, of both varieties is essentially the same ; that is to say, they consist chiefly of the phosphate of lime; a substance which appears to be never deposited in an unmixed state by the urine. Hence the prostatal calculi can be always readily distinguished from those of urinary origin." (p. 94.) Astley Cooper (6) says, the largest he has seen " are not bigger (a) Inquiry above cited. (b) Surgical Lectures, vol. ii. PROSTATAL STONES. 367 than a pea, and they seldom are so large but their numbers are sometimes very considerable." (p. 295.) In a preparation of this disease in St. Thomas's Museum, the prostate is studded with little stones like pins' heads of various size. Astley Cooper mentions, that in a case under his care, " these calculi had produced not only painful feelings in the perineum, but a degree of irritation which kept the patient in continued mental excitement bordering on insanity." (p. 296.) They are usually accompanied with difficulty in passing the water; may be felt as the catheter passes over them into the bladder, and by the introduction of the finger into the rectum. These prostatal stones must be removed by cutting through the peri- neum into the prostate gland, and picking them out. [I am doubtful whether the following is to be considered as a prostatal stone, or merely a stone encysted close to the gland, but it has much practical interest, and may be conveniently mentioned here. A man about middle age applied several years since to my friend Green, labouring under symptoms of stone in the bladder. He was sounded, and a stone felt obscurely; but was sounded again at some interval, and with the same result; the operation was therefore deferred, and a few months after he died of some other complaint. On examination no stone was found in the bladder, although sounding immediately before had given the same indistinct sensation. The bladder, penis, and neighbouring parts were therefore removed for closer inspection, and it was then found that there was a long narrow stone embed- ded in a cyst before and below, but in such way that had the lateral operation been performed, and the prostate divided in the usual way, the forceps would probably have entered the bladder without detecting the stone in their passage, and conse- quently the operator would have had the vexation of supposing the patient had been operated on without really having a stone; although as the sound passed over it had received the indistinct impression before mentioned.—j. f. s.] Mote on Constitutional Stone-Solvents. I have to thank my friend Travers for the following interesting case which fell under his own immediate observation, and which is the best authenticated throughout of any case I have heard of. The fragments of the stone are in his pos- session. A tailor who had long laboured under symptoms of stone was sounded by Tra- vers a few years since, who detected a hard calculus of some size, and counselled immediate operation. The man being afraid to incur the risk of the proceeding, put himself under the care of a person at Henley-in-Arden, who administered a consti- tution water to the extent of two or three pints per diem. The patient soon began to pass fragments in quantity, as after the operation of breaking, the act being attended with acute pain,' both before and during micturition. The pain and discharge oT fragments continued for many months; both subsided at last and at the same time. The patient on one occasion showed him a box full of fragments, for the most part reduced to a powder. This man was examined after death by Dr. Charles of Putney, and no trace of stone was discovered in the bladder. Dr. Prout stated the basis of the " drink" to be carbonate of soda and potass, with a little nitre, in the following proportions :— Sodae carb......gr. x. , Potass, carb......gr. viij. ------nitrat......gr. ij. [ 368 ] SATISTICAL ACCOUNT OF THE OPERATIONS FOR THE STONE IN ST. THOMAS'S HOSPITAL, from 1800 to 1846. The following is the account of operations for the stone which have been performed in St. Thomas's Hospital since 1800; and I have to thank my friend Nash for the kind assistance he has rendered me from the steward's office books, which unhappily are, but with few exceptions, the only records kept before 1820. I have also used Green's case-books, some of which are missing, Clark's, and my own books, the ward books, and the lancet from which I have derived great assistance. In the first table are the gross number of cases operated on in each year. In the second table I have given the dates and the results, with the circumstances of the cases where important, as far as I have been able to obtain them. I am sorry, however, that the reports are so meagre, but still they are highly important, as show- ing that the lateral operation is neither so dangerous, nor so much to be dreaded, if the after-treatment be well attended to; and also that the cutting gorget does not deserve the obloquy which of late years it has been the fashion so freely to heap upon it. In the cases recorded in the second table, the gorget was always used by the elder Travers, Green, Mackmurdo, the younger Travers, and myself; Tvrrell, Solly, and Clark operated with Blizard's knife, its beak, however, being straight. TABLE I. Gross Number t)F Operations for the Stone, from 1800 to 1846. 1801 12 1813 7 1825 4 1837 10 1802 12 1814 2 1826 5 1838 7 1803 1 1815 8 1827 7 1839 1 1804 6 1816 5 1828 13 1840 7 1805 11 1817 2 1829 9 1841 6 1806 4 1818 7 1830 10 1842 4 1807 3 1819 8 1831 6 1843 7 1808 11 1820 8 1832 4 1844 6 1809 4 1821 4 1833 5 1845 2 1810 2 1822 7 1834 5 --- 1811 15 1823 11 1835 5 295 1812 4 1824 10 1836 8 T AB L E II. Yhe Initials under the Surgeon's column mark the operator. Up to 1837, the elder Travers, Green, and Tyrrell, alone operated; but in that year, whilst Assistant Surgeon, was my first operation. After.the retirement of Travers, and my appointent as Surgeon, in 1841, Mackmurdo, Solly, and the younger Travers, became Assistants; and on the death of Tyrrell, in 1843, Mackmurdo took his place, and Clark became junior Assistant. This notice is necessary, as a key to the Table. Age. Admit'd Cut. 1 Cured. Surgeon. Remarks. 1S22. (Seven.) James Townrnw.... (Ward Book.) May 30 June 7 July 4 G. Elizabeth Dnnthorne (Ward Book.) June G July 12 Aug. 22 G. Robert Brown....... (Ward Book.) Aug. 1 Aug. 23 Sept. 2b' G. Charles Johnson.... (Ward Book.) (a) Aug. 24 Oct. 15 Nov.l 2 G. («) The names of tlr remaining patients cannot be. ascertained; but the total number is obtained from the Steward's report in table I. STATISTICAL ACCOUNT OF OPERATIONS FOR THE STONE. 369 Age. Admit'd Cut. Cured. Surgeon. Remarks. 1823. (Eleven.) 6 Oct. 30 Nov. 7 Dec. 13 Tr. Stone as large as pigeon's egg. (Lane, vol. i.) 39 Nov. 22 Nov. 28 Dee 22 Tr. • Stone rather larger than (Lane, vol. i.) crown-piece, not very thick. Uric acid. Had slight bleed- ing on same evening, but it was soon stanched. Sept. 4 Jan. 4, G. (Ward Book.) 1824. (a) 1824. 3 Feb. 13 Tyrr. Two stones removed'. (Lane. vol. ii) April 28 May 21 July 15 G. (Ward Book.) 3 Nov. 4, Mar. 12 April 29 Tr. Stone not found at operation^ (Lane, vol. ii.) 1823. but afterwards in a clot on the floor, size of a pea and oblong. Soon after his ad-mission a small stone was extracted from opposite/r tion broken off in the ex-traction. May 28 Tyrr. (Lane, vol. iii.) William Padyham.. (Lane, vol. iv.) Aug. 16 Aug. 27 Tyrr. Oct. 7 Oct. 22 Nov. 28 G; (Ward Book.) Dec. Tyrr. (Lane, vol. v.) 1825. 4 Feb. 10 Feb. 26 Mar. 25 G. Operatedon in 1823. Oblong- (Lane, vol. vi.) stone, inch long, half inch (see 1823.) wide. 7 Aug. 3 Aug. 9 Sept. 12 G. Flattened round stone, three (Green's Book.) inches around, rough. 45 Oct. 4 Oct. 14 Frb. 23, G. Had been cut in Oct., 1824; (Green's Bonk.) (sie Id*.) 1826. stone broke in present ope- ration; passed fragments, on second and third day. 7 Nov. 3 Nov. 11 Dee. 15 Tr. Stone large: had shivers on (Lane, vol. ix.) fifth day. 1826 Anthony Willsmore. (Lane, vol. ix.) 12 Feb. 23 Mar. 3 April 24 G. Oxalate of lime. (o) The names of the remaining patients cannot be ascertained; but the total number is obtained from. the Steward's report in Table I. Vol. hi.—32 370 STATISTICAL ACCOUNT OF 1826—continued. Charles Cruden.. (Lane, vol. x.) Heber Humphrey. (Lane, vol. x.) Age. 17 John Palmer...... (Lane, vol. x.) John Newman..., (Green's Book.; 1827. John Bone.......... Robert Gosling or Gosden. Henry Richardson.. (Lane, 1827—28; vol.i.) Edward Row...... John Gilby.---..... James Sharp....... (Lane, 1827—28; vol. i.) George Butler...... 1828. John Baker........ (Lane, 1827—28; vol. ii.) John Chaplin.,..... (Lane, 1827^--!8; vol. ii.) John Gilby.......... (Steward's book.) James Gardner..... (Lane, 1.827—28; VOL ii.). Frederick Hinckley (Lane, 1827—28; vol. ii ) John Maybank..... (Lane, 1828—29; vol.i.) Thomas Gash...... (Steward's book.) W'H'ar" Shaw....... (Steward's book.) Admit'd June 1 June 2 June 29 July 3 July 8 Nov, 25 S3 a* July 21 Nov. 25 66 Feb. i5 Mar. 8 June 8 Cured. June 29 Aug. 9 Surgeon. Aug. 25 Jan. 25 Feb 22 April 3 Mar. 16] May 17 June 22 Aug. 8 Aug. 25 Sept. 19 Nov. 29 Feb. 28 April 9 April 26 Aug. 4 Aug. 14 Sept. 4 Oct. 1 Oct. 12- Aug. 10 Aug. 25 Sept. 27 Dec. 7 Mar. 7 April 18 w Tr. Tr. G, Tyrr. Sept. 11 Sept. 4 Nov. i5 Jan. 3. 1828. April 10 June 14 May 8 Oct. 2 Aug. 1,9 Tr. Tr. Tr. Oct. 2 Nov. 6 Nov. 20 Dec. 25 Tyrr, Remarks. Size of sparrow's egg. Size of walnut. In same evening patient attacked with great pain in abdo- men, with high excitement; arising from accumulation of urine, from closure of wound; a catheter passed through it, and symptoms ceased, but required to be passed next day; no further trouble. Stone size of horse chestnut; flattened, and rough. Stone as big as top of little finger, and grape-shaped, in bulb of urethra, causing re- tention of urine; removed by cut in perimeum. He had been repeatedly sounded, but the stone never felt. Stone size of a pigeon's egg immediately, after which, with much difficulty, a se- cond as large as a pullet's egg; much venous bleeding at operation ; on third day powers failed, and died on fourth. Large stone in right ureter, and same kid- ney wasted; bladder much thickened, with spots of ulceration; prostate en- larged, and almost cartila- ginous. Stone oval; flattened, size of a shilling, rough; oxalate of lime. Stone as large as hazel-nut. Stone size of a horse bean. Stone size of a pullet's egg, rough; considerable bleed- ing some hours after; stop- ped by pressure. Much constitutional excitement, and sickness for first five days. First division of prostate not sufficient, therefore a se- cond; stone small and ob- long; seized with difficulty, as lodged behind a fold of bladder, and lying behind and below left of prostate. Stone large and^irregular. Stone of large size. Died, [oj June 25,1827, OPERATIONS FOR THE STONE. 371 Age. Admit'd Cut. Cured. t Surgeon, Remarks. 1828—continued. Edward Harrison... 9 Oct. 18 Oct. 24 Jan. 22, G, Stone large. Attacked with (Lane, 1828—29; 1829. peritonitis on second day. vol. i.) 17 Nov. 27 Feb. 24, G. (Steward's book.) 1829. Dee 15 Feb. 7, 1829. Tyrr. (Steward's book.) Dec. 12, Mar. 7 W: G. . Third operation, against (St. Thos. Med. 1827. Green's advice; cut made Soe Minute-Book ) on inner side of scar; great (see 1824—25.) difficulty in introducing gorget, on account of hard-ness of prostate; stone broken to pieces, and re-moved piecemeal, but nu-cleus remained, and neces-sary to enlarge wound with straight knife, then broke, 1829. and extracted in two pieces; operation forty minutes. 62 Jan. 9 Feb. 30 lb} G. Two stones; first of large size; second broke to (Lane, 1828—29; vol. i.) pieces, partially removed with scoop, and washed out by injecting warm water; patient much exhausted. iv- 9-i- Sr- xv' Botn ""* acid. Stone crushed. Weight, gij. gr. xv. Nucleus, uric acid, with traces of oxalate of lime; the re- mainder oxalate of lime. Mack. Had been lithotritized two years since, but no frag- ments passed at or after the operation, which was followed by a severe attack of irritative fever, from which he did not recover for several weeks. Though much urged, he would not submit to a second lithotritie operation, on account of the severity of the pain he had suffered. In the present operation for lithotomy, the forceps were withdrawn with some difficulty, containing four seemingly distinct and unequal-sized stones, weighing together zxi. gr. xiv., of which the largest exceeded the united bulk of the other three. On careful examination, these were evidently the fragments of one single stone, which they readily formed by properly placing, and bad been, doubtless, broken in the lithotritie operation; the broken surfaces had become coated afresh. The stone is uric acid, coated with phosphates. Solly 14 66 12 Geo. Will. Langfoid James Landon..... Joseph Bishop...... Henry Tabernacle 2£ 34 62 34 May 27 June 15 July 29 Sept. 21 Sept. 2, 1841 June 14 July 28 Aug. 13 Jan. 14 Jan. 24 Jan. 31 Feb. 1 Aug. 23 July 1 June 22 Aug. 5 Oct. Mar. 3 July 9 Oct. Sept. 17 Feb. 4 Feb. 4 Mar. 11 Feb. 11 July 22 Aug. 3 Sept. 14 April 3 Aug. 13 Nov. 3 Oct. 29 Mar. 11 Mar. 4 April 15 April 27 Nov. 18 Jan. 9, 1844 Tyrr. Tyrr. Tyrr. Tyrr G. Mack. Mack. B.Tr, B.Tr Soil) Stone small, and consisting of triple phosphate. Nucleus, oxalate nf lime eo. vered with uric acid, upon which a layer of phosphate and carbonate of lime mix- ed ; crust of phosphate of lime. Weight, ?iv. gr. x.; oxalate of lime'thickly coated with phosphates. Uric acid. Stone broken to pieces, and not analyzed. Nucleus of uric acid, next layer oxalate of lime; crust, uric acid. Uric acid, with traces of fu- sible calculus. Weight, gr. vj. Impure oxa- late of lime. Nucleus, oxalate of lime, »ne remainder uric acid mixed with a little oxalate of lima. This patient had been litbotri- tized ten times previouil^ 1CJ1. -------- - , and was passing large quantities of triple phosphate at the period of the operation oi lithotomy, in which two triple phosphate stones were removed. Died, [a] Jan. 8,1839. [J]Oet.5, OPERATIONS FOR THE STONE. 375 1843—-continued. Joseph Burgess..... 1844. William Lapworth.. William Evenden... smaller; both consisting of uric acid. Much venous bleeding, which was not checked for two hours and a half. William Sparkes.. George Sawyer. John Snooks... John Easton... 1845. Henry Smith... Nathan Robins Age. Admit'd Cut. Cured. Surgeon. Oct. 30 Nov. 14 Dee. 19 . . . Solly Stone pyriform, 1J inches long, with four small no- dules at extremities, and weighed gvii. ^'j- Nucleus of each stone triple phosphate, and the remainder composed of layers of oxalate of lime. Remarks. 74 Dec. 5, Jan. 1843. Dec. 23,1 Jan. 1841 6 Feb. 6 8 Mar. 26 Solly Stone, size of kidney bean ; uric acid. Two stones, one size of a walnut, the other a third 47 April 6 . fo] . . . [Solly (Extensive ulceration of kid- I | I | | neys. Large nucleus of animal matter, seemingly a clot of blood; the stone composed of uric acid and oxalate of lime. 44 11 July 111 July 27, Nov. 10 Aug. 20 Sept. 161 Oct. 22 Aug. 20 May 6 Sept. 9 Oct. 5 May 30 Dec. 3 July 18 L*J Mack Mack. Mack. Nucleus, uric acid; remainder oxalate of lime mixed with uric acid. Nucleus, oxalate of lime; next layer, uric acid, with traces of fusible calculus covered with oxalate of lime; the orust, fusible calculus and uric acid mixed. Scarlet fever appeared on the fifth day. After death it was found bis family were infected when he left home. South. Clark. Weight, gr. xlvii.; consisted of urate of ammonia, with a trace of urate of lime. Oxalate of lime. Died, [a] April 18. [6J Oct. 20. [The analyses of the greater number of the above stones are by Dr. Leeson, and copied from St. Thomas's Museum Catalogue. Those of Lucas, Borer, Wvbrkw, Landon and Snooks are by my friend Thomas Tavlor. I should be much obliged by any St. Thomas's pupil communicating to ine notes of any cases of stone which he possesses, of which Ihavebeen unable to obtain particulars: more especially of those in the early part of this table, so as to render it more complete.—j. p. s.j [OF LITHECTASY. Lithectasy, or Cystectasy, which has been, within the last few years, warmly advocated by Dr: Willis (a), has for its object the removal of stones from the bladder, without division of its neck. The operation consists in opening the urethra, in the perineum, behind the bulb of the penis, to the extent of a few lines, and then slowly dilating the mem- branous and prostatic portions of that canal, and the neck of the bladder. How far this mode of treatment will succeed has yet to be tested by experience; but I am disposed, with Fergusson, to believe, that the neck of the bladder would not be so surely uninjured by the dilatation as is presumed. The original proposer of this method appears to have been John Douglas (b), who 6eem6 to have been led to it by having noticed the passage of small stones through the fistulous canals, left after the operation with the great apparatus, as performed by Mariana, and already mentioned, (p. 571,) and also by the natural escape of stones through the dilatation of the short urethra of women. He, therefore, pro- posed the establishment of a perinseal fistula, so that, as near as might be, the opportunity for the escape of a stone from the male bladder, should be similar to that from the female bladder, in both cases requiring little more than the dilatation of the neck of the bladder. He then put the question, " Whether it be not possible to dilate the artificial fistula in the perinaeum of males, and the urethra in females with sponge or gentian tents, gradually increased for some time to such a width that (a) On the Treatment of Stone in the (b) Two Chirurgical Questions stated and Bladder by medical and mechanical means, answered; in Phil. Transactions vol xxxiv London, 1842. 8vo. p. 318. 1726,27. 376 LITHECTASY. we may easily pass a pair of forceps into the bladder, with which the stone, when small, may be extracted, and when large or of an irregular figure, broke, and the pieces extracted gradually, and at different times, when they cannot be extracted at once, without fatiguing the patient too much," (p. 320,) and after discussing the subject, he concludes:—"Therefore, artificial fistulas in males, and the urethra in females, may be dilated so as to extract any stone, without cutting the body of the bladder, or lacerating any of the parts." (p. 322.) It does not appear, though Douglas proposed, that he ever practised this method, and like many other proposals, it was lost sight of for many years; still, however, it is his operation, though Dr. N. Arnott (c) says, " that the means proposed by Douglas are inadequate " for its performance; forgetting however to mention that Douglas had honestly referred to a case of Collet's (b), in which a perineal fistula after lithotomy had been success- fully dilated with sponge tent, as in Douglas's proposed operation. In 1819, however, Collet's plan was suggested and practised by Dr. Arnott (c), in a case under the care of Astley Cooper, for a recto-vesical fistula of nine months' standing, after an unsuccessful operation for the stone, in which the rectum had been wounded, and the stone left in the bladder. For the relief of this fistula, Astley Cooper, made an opening into the urethra, from the perinaeum, and introducing a female catheter, immediately struck a stone. This not being expected to be large, Astley Cooper yielded to Arnott's proposal of dilating the passage from the peri- naeum into the bladder with his fluid-dilator instead of sponge tent; after the em- ployment of which, for thirty hours, the passage from the perinaeum to the bladder was enlarged to three-quarters of an inch in diameter, and Cooper then introduced a pair of stone-forceps, and extracted a stone as large as a moderate-sized walnut. Stimulated by Willis's enthusiastic expectations, Elliott of Carlisle (d) per- formed this operation in July, 1842, on a lad of seventeen, with the variation of making the wound larger than recommended by Willis. " The different steps in the operation were precisely the same as in lithotomy, until the prostate and mem- branous part of the urethra were exposed. The latter was opened close to the pros- tate, and divided cautiously towards the bulb by carrying the knife along the groove of the staff till an opening was made of sufficient size. The staff was then withdrawn, and the point of the forefinger of the left hand served as a guide for the introduction of the dilator, which, having been previously well greased, was passed along without difficulty. A little warm gum mucilage was next slowly injected into the intrument, until the patient slightly complained of the feeling of distention. On removing him from the table to the bed he complained of a strong inclination to make water, which was found to arise from the dilating part of the instrument having slipped into the bladder. It was emptied, partially withdrawn, and, when fairly within ihe neck of the bladder, again distended. Another opiate was given, one having been given before the operation. In three hours' time a few teaspoonfuls of the mucilage were again thrown into the dilator till the patient complained. The urine had passed freely along that part of the tube which communiaated with the bladder." He went on well; no further injection was made; but in the middle of the following day he was a little uneasy, and another opiate was given. At the end of twenty-five hours Elliott "emptied the dilator and withdrew it, at the same time passing his left forefinger along it into the bladder. He immediately felt the stone, which was of Bmall size, and in shape resembled a coffee bean, but about four times the size. It was removed with the scoop and finger," (p. 137,) and a lithotomy-tube introduced. In his remarks on the case, Elliott advises the dilata- tion " being done at intervals, for, say a quarter of an hour at a time, as less likely to cause irritation than if continued for a period of thirty or forty hours, as has been mentioned, (p. 139.) Dr. Wright, of Alalton, Yorkshire (e), performed the second lithectasy on a man of sixty, in the autumn of the same year, and made "an opening a few lines in ex- tent into the membranous paTt of the urethra," but could not introduce the dilator, evidently for want of room; attempts were made to enlarge the passage sufficiently with bougies for its admission, but it could be only imperfectly got in, and was left without distending it till three days after, when the injection escaped, the bladder- part of the instrument having rotted." Another instrument was then passed with (a) Lancet, 1842.-43; vol. ii. p. 612. (.d) Edinburgh Medical und Surgical Jour- (b) Traite de la Taille. nal, vol. lix. p. 135. (c) Essays on the different modes of ex. (e) London .Medical Gazette, vol- xxxiv. p, trading Stone from the Bbddcr, by James 77. 1843-44. Arnott. London, 1821. 8vo. LITHECTASY. 377 difficulty, but the patient could not bear the distention, and during the following weeks suffered much constitutional excitement. Not till the eighth day after intro- ducing the second instrument could any progress be made with the distention, but then it went on rapidly, and on the eleventh, "the urethra having been dilated to as great an extent as the instrument would allow, an effort was made to extract the stone. It was seized with the lithotomy forceps, but it was discovered to be too large to remove entire without using more violence than was thought prudent or safe." (p. 79.) The stone was, therefore, broken up with Fergusson's lithotrite, and brought away piece-meal; it weighed a little short of two ounces troy." (p. 78.) The patient did well. Wright inquires, " Would it not be better to make the incision in front of or anterior to the bulb, where the canal is so superficial that it could be opened by a mere scratch ? It certainly requires no formidable incision to reach the membranous portion: still it must be of some depth, and it occurs to me as just possible that on introducing the dilator, its extremity might be carried past the opening in the urethra into the surrounding cellular tissue. I imagine the bulbous portion would be dilated as easily as the membranons part of the urethra" (p. 79.) In June 1843, Fergusson (a) performed the third lithectasy in a man of sixty-four, who had suffered very severely, and for five years had been continually passing stones as large as peas. The urethra was opened by "an incision along the raphe about one inch and a half in length, terminating about half an inch in front of the anus, from which point two incisions, each about three-fourths of an inch in length, were carried downwards and outwards. The superficial cellular tissue being divided to a similar extent, the point of a knife (a common lithotomy bistoury) was thrust into the groove of the staff a little in front of the triangular ligament. The edge of the blade was so applied as to divide the triangular ligament to a slight extent, first downwards and outwards on one side, and then in a similar way on the other; the groove of the staff being then distinctly felt by the forefinger of the left hand, the metal point of an Arnott's dilator was placed within it, and slid cautiously into the bladder. The staff was next withdrawn, and the bag of the dilator was partially distended with a solution of gum arabic, the distention having been continued until the patient complained of pain." Additional quantities of fluid were repeatedly thrown in for the first two hours; again, at the third, and at the end of the fourth, the instrument being fully distended, was withdrawn, and another larger one having a passage through it for the escape of the urine, was introduced. At the ninth hour, a larger instrument was passed, and directed to be distended as the patient could bear it. At the twentieth hour, this dilator, an inch and a quarter in diameter, having been fully distended, was removed, and the stone attempted to be removed with the scoop several times unsuccessfully, as it brought away only fragments. Forceps were also used, but the stone was too large to pass, and was therefore broken by forcibly closing the blades; the pieces were readily removed. Constitutional excitement, however, came on, and he died on the evening of the sixth day. On examination, the principal circumstance was that " the cellular tissue between the bladder and rec- tum, and that lying on the outer surface of the gut was softened, and slightly infiltrated with a sero-purulent fluid." (p. 576.) It would seem from Fergusson's observa- tions, that he thought the distention had been made too quickly; for he says:— " Unless the dilating process were effected in a much slower manner than was recommended for lithectasy, he feared that the mucous membrane and urethra would not only be dilated, but actually torn." (p. 577.) And further, that " it was one of the main objects in lithectasy to avoid any wound of the neck of the bladder; but he doubted if this could be avoided, and a certain amount of inflammation might, therefore, be calculated upon." * * * On any future occasion, he should suggest that a longer period should be expended in using the dilator, and also that the event of the stone proving too large for ready removal, the lithotrite should at once be used. * * * It was his opinion that in such an operation there would always be greater difficulty in extracting a stone of any considerable size than in lithotomy; for in the latter case the wound extended down alongside of the anus, and the forceps holding the stone could be more readily depressed, whilst in the former, (lithectasy,) the manoeuvres were conducted near the angle of the pubes, and consequently in the nar- rowest part of the space between the bones, a space which the experienced lithoto- mist was always careful to avoid." (p. 578.) (a) London Medical Gazette, vol. xxxiv. p. 77. 1843-44. [ 378 ] FIFTH DIVISION. OF DISEASES WHICH CONSIST IN THE DEGENERATION OF ORGANIC PARTS, OR IN THE PRODUCTION OF NEW STRUCTURES. Astruc, J., M. D., Traite des Tumeurs et Ulceres; avec deux Lettres, &c. Paris, 1759. 2 vols. 12mo. Plenck, J. J., Novum Systema Tumorum, quo hi Morbi in sua genera et species rediguntur. Viennae, 1767. 12mo. Dumas, Sur les Transformations des Organes; in Sedillot's Journal de Medecine, vol. xxiii.-xxv. Abernethy, John, An Attempt to form a Classification of Tumours according to their Anatomical Structure; in his Surgical Works, vol. ii. Second Edition. Lon- don, 1816. Laennec, Note sur 1'Anatomie Pathologique ; in Corvisart, Leroux et Boyer's Journal de Medecine, vol. ix. p. 360, an xm. And Article Jinatomie Pathologique; in Diet, des Sciences Medicales, vol. ii. p. 46. Cruvelhier, Essaies sur 1'Anatomie Pathologique en general et sur les Trans- formations et Productions Organiques en particulier. 2 vols. Paris, 1816. Meckel, Handbuch der Pathologischen Anatomie, vol. ii. part ii. p. 111. Baron, J., M. D., An Inquiry Illustrating the NatHre of Tuberculated Secretions of Serous Membranes, and the origin of Tubercles and Tumours in the different textures of the body. London, 1819. Caspar, Zur Lehre von den Afterorganisationen; in Horn's Archiv. fur Medicin- ische Erfahrung, vol. ii. p. 385. 1821. Heusinger, C. F., System der Histologic, vol. i. part i. ii. Eisenach. 1822-23. 4to. von \\Lalther, Ueber Verhartung, Scirrhus, harten und weichen Krebs, Medullar- Sarcom, Blutschwamra, Teleangiektasie und Aneurysma per anastomosin; in Journal fur Chirurgie und Augenheilkunde, vol. v. part iii. Lawrence, William, Observations on Tumours, with Cases; in Med.-Chir. Trans., vol. xvii. p. 1. 1832. Warren, J. C, Surgical Observations on Tumours. Boston, 1837. 8vo. Ritgen, Ueber Afterbildungen; in von Walther's Journal, vol. xi. Muller, J., Ueber den feineren Bau und die Formen der krankhaften Geschwulste. Berlin, 1836. fol. Vogel, J-, Icones Histologiae Pathologicae. Lips., 1843. —'■------; in R. Wtagner's HandwOrterbuch der Physiologie mit Rucksicht auf physiologische Pathologie, Art. Gewebe (in pathologisoher Hinsicht.) 2147. The two classes of disease to be considered in the present sec- tion,,to wit, the degeneration of organic parts and the production of new structures, agree together so far as a general character of the degeneration of organic parts, is, that the enlargement of the surrounding parts depends not merely on the increased deposits into them of the matters forming them in their natural state, but that in the parenchyma of the part, more or less, of such matter foreign to their natural structure, is produced and DISEASED CHANGES OF STRUCTURE. 379 deposited; hence is it often very difficult to determine, whether a dis- eased structure is to be attributed to the change of the organ, or to a new formation. [Lawrence has well observed:—»" It is not easy to draw a clear distinction between new or accidental prpductions and changes of structure, or degenerations of organs. There is no definite boundary between them; on the contrary, as in other diseases, there is an insensible transition from one to the other. In the case of Fungus haematodes, we find the same structure sometimes occurring as a new pro- duction, an independent tumour; sometimes as a change of structure in a part. Indeed, we meet with this growth in three distinct forms; viz., as a deposit enclosed in a cyst, as an unencysted formation, and as an infiltration in the substance of an organ. Again, we find a similar gradual transition between the structures composing various kinds of tumour, so that We often hesitate in deciding to which species a particular swelling should be referred. As the same gradual blending of one form into another occurs throughout the whole field of disease, we cannot wonder that the several attempts at reducing its infinitely diversified phenomena to an artificial arrangement of classes, orders, genera, species and varieties should have failed.'7 (P- 4-)] 2148. All degenerations of organic parts appear to have their origin in a local increased vascular activity, on which depends the deposit of a substance more or less resembling the elementary parts of the organ, or of a peculiar substance, in the interstices of the part, in which by the shooting forth of the Vessels, and their very extensive ramifications, the unnatural formative disposition is sustained, and the growth of the tumour increased. We find, therefore, also in most cases, that although there be no characteristic signs of inflammation, yet that increase of tempera- ture, peculiar sensibility on pressure, tension, and the like accompany the beginning of degeneration. In most cases, the increase of vascular activity is not to be distinguished by the symptoms which characterize it; for little as we can comprehend the natural growth and development of organs without increased activity of the vital processes, just so little can we understand it in diseased structures. Development of vessels, diseased secretion, continued production of the secreted matter, with growth of vessels in it are the processes, in which the course of these diseased formations are constantly repealed. The unnatural commixture and condition of the juices, and the large quantity of inorganizable matter may indeed effect the separation of peculiar substances, distend, increase, and change the tissue of different organs ; but special degeneration with self-active production, proceeds only with increased development, and multiplication of vessels. Secreted inorganizable matter remains either in that state, or hardens, and then first operates on the surrounding parts, but always remains without vascular connexions, and is destroyed in a purely chemical manner, as the history of the formation of tubercles shows, although even they may be converted from the formless condition into cells. 2149. In the diseased changes of organic parts, either the vessels, arteries, capillaries or veins, often the one more than the other, are spe- cially developed, or the uninjected part of the cellular tissue is specially prevalent by the deposit of formless matter, or both exist at the same time in different proportions. If these conversions depend only on quantita- tively changed nourishment, they can increase to an enormous extent, without otherwise than mechanically operating destructively; they sup- port themselves like the natural tissues, and participate in the general 380 PRODUCTION OF NEW STRUCTURES. change of matter. But if there be at the same time a qualitative change of the nutritive matter, if they depend on general diathesis, and alteration of the formative disposition, they have a specific character, are accom- panied with reaction of the whole organism, and draw all the tissues without distinction of their organization, into the same diseased change; they cannot retain their development unchanged in the highest degree, but according to their nature are destroyed and pass into softening. Hence arises the division into benignant and malignant tumours. 2150. The after-products, which must be considered as new forma- tions, are either repetitions of natural formations, as the adipose and encysted tumours, and the like; or they are formed from substances foreign to the natural composition of organic parts, as, for example, medullary fungus. They are vegetative formations, which simply by their further growth, compress the neighbouring parts, do not convert them into the same mass, for instance, adipose tumours, cysts, polyps, and the like ; they are inconvenient, therefore, only by their size. But others possess the above-described specific characters, consequently have a fatal reaction on the whole body, and draw the neighbouring tissues into the same diseased change. Diseased growths are subject to the same general laws as are the origin and development of the natural tissues. According to the results of microscopic ob- servation, two theories have been put forth on this subject, to wit, the cellular theory and the corpuscular theory. According to the cellular theory, there is every where at first a simple formative matter, cyloblastema, in which are formed nuclear cells, cytoblasts, and in them cells are produced; or the nuclear cell is formed first, and the cell walls are formed secondarily around it. In many cells the pathologic tissue is perfected with the complete development of the cell. In general these first-formed (primary) cells undergo still further changes, and from them are produced elementary parts, which exhibit no more of the original cellular form. It is usually then the cell-walls which pass into the remaining parts of the organism, more rarely do the nuclear cells undergo a still further development, and still more rarely do organic pathologic tissues arise, the development of which can never be traced to a cellular formation. It is highly probable that the nature of the subsequently produced tissue does not depend on the nature of the cytoblast, but upon the subsequent accession of external influences. According to the corpuscular theory, the formative corpuscles are produced in the plastic matter by clotting together. In the midst of this matter, consisting of granules and formless matter, a formative corpuscle arises, and a nucleus, composed of a homogeneous tough matter, which continues increasing, so that at last there remains only a thin peripheric layer, which also becomes changed. In this nucleus a great quantity of molecular corpuscles are formed. The corpuscle then drops in on either side, and the middle protrudes, so that it resembles a knife-like body, and passes into the form of haematoids, or ring-shaped bodies, a nucleus with a ring. Of the formative as well of the haematoid bodies, one part lies unconnected with the rest and moveable; this is the blood corpuscle; the other part is connected by con- tiguous linear ranks, by layers of plates and heaps of corpuscles, and forms the tissue (a). 2151. The tumours produced by those unnatural formations, which are not to be considered as repetitions of natural parts, belong to the most difficult subjects of the healing art; they may be considered in reference to their origin, their further development, or to their manifold differences, (a) Vogel, above cited.—Baumgaertner Lehre von den Gegensatzen in den Kraften irn leben den thierischcm Koper cin Grundriss zur Physiologie und allgem. Pathologie und Therapie. p. 32. Stuttgardt, 1842. Second Edition.—Arnold holds the same views as Baumgaertner. KINDS OF TUMOURS. 381 for the purpose of grounding thereon their classification. In former times the various swellings of this kind were spoken of under the general designations, scirrhus, carcinoma, sieatoma, and the rest. More careful inquiry has, however, recently showed remarkable differences in the nature of the diseasedly-produced substances which form these tumours, and upon these it has been attempted to class them. 2152. Abernethy points out five peculiar kinds of tumours, to wit, the pancreatic, mammary, pulpy or medullary, tuberculated and carcino- matous Sarcoma. Laennec admits a fourfold variety of the tissue in which these tumours are formed, namely, the tuberculous, scirrhous, cere- briform, and melanosis. Meckel considering Laennec's melanosis the same as Abernethy's tuberculated and medullary sarcoma, points out six different tissues, the pancreatic, the mammilloid, the cerebriform ot medullary, the scirrhous, and the tuberculous or scrofulous. 2153. John MTiller (a) has very recently endeavoured, from micro- scopico-chemical observations, to found a division of tumours, according to their chemical nature, their microscopic structure, and the manner of their development. In reference to their chemical composition, all tumours are, according to the elementary parts of which they consist, either fatty tumours, jelly-yielding {b), or albuminous tumours; other substances, as osmazome, saliva, caseine, and so forth, may indeed be present in them, but only in small quantity proportionally to the principal elementary parts. The more minute microscopic elements of tumours are, besides capil- lary vessels, fibres, granules, cells without and with nuclei, tailed or spindle-shaped corpuscles, vessels, and by far the most common element is cells. The principle of dividing tumours into groups can be obtained neither merely from their minute structure nor their chemical nature; for tumours the most differing in reference to their physiological nature and curability, may equally possess the most delicate structure ; in similar structures chemical differences may exist; With similar chemical nature, there may be difference of structure, or difference in respect of physiological pecu- liarities and curability. In the formation of groups these several points must be taken into consideration. 2154. These various opinions serve to prove how difficult it is to make an accurate and sufficient division of tumours dependent on their un- natural structure. The ground of this difficulty rests, without doubt, on the manifold changes to which the diseased matter is subject in the yarious periods of the development of the tumour; further, on the undis* tinguishable influence which the natural structure of an organ has upon the after-formation developed in it, and on the variety of Causes upon which it depends. There are, therefore, tumours, in which are present, at the same time, several of these diseased products, either lying near to, or intimately connected with each other. But if pathological anatomy be of direct use and immediate application to practical medicine, it must not rest on the mere examination df the changes of organic parts and of (a) Above cited. (b) This is a well-chosen designation, as their soft and solid parts contain the ma- it is shown by Thknard' that "gelatin does torials proper to its production." Traite de not exist in the humdurs" df animals ; but all Chimie, vol; iv. p. 379. 1827. Fifth Edition. Vol. hi.—33 ^ 382 ENLARGEMENT OF THE TONGUE. the substances forming the tumour, and assume these alone as the ground of division ; but it must at the same time consider the symptoms, course, and effect upon the immediate neighbourhood, and the whole body, if it would not be seduced, by incorrect particulars, into subdividing similar diseased conditions. Under this supposition, the number of tumours founded on the above-mentioned variety of diseased tissue, may be con- veniently referred to three, namely, medullary fungus, scirrhus, and tubercle, in which case the pancreatic and mammary tissues are to be considered merely as accidental modifications of the medullary (a). 2155. These unnatural structures, completely foreign to the natural composition of the organism, may agree in general with each other; they consist, probably, or for the most part, of albumen, their tissue is more or less distinctly cellular; they contain a fluid of various consistence, and enclosed in differently-shaped cells ; at first they are harder than in the subsequent periods of their development, and then are for the most part harder than the organs in which they are met with, in which case they soften, and are converted into a fluid, or into a substance of looser tex- ture. Their form is for the most part more or less round; they strive to destroy the neighbouring parts, and the organism which are drawn into the same diseased structure, or displaced by pressure, and further propagate the diseased affection by the lymphatic vessels, and perhaps also in other ways. L—OF ENLARGEMENT OF THE TONGUE. (Prolapsus Linguae, Macroglossa, Lat.; Vorfall der Zunge, Germ.; Hypertrophic de la Langue, Fr.) Clanny, W. R., M.D.; in Edinburgh Medical and Surgical Journal, vol. i. p. 317. 1805. von Siebold, C, Beobachtung iiber die Verkiirzung widematurlich zu grosser Zunge; in Chiron, vol. i. p. 651. Klein, Beobachtung einer durch Abschneidung abgekiirzten verlangerten Zunge; in Chiron, vol. i. p. 665. Percy, Article Langue (Pathologie Chirurgicale); in Diet, des Sciences Medi- cales, vol. xvii. p. 244. Mirault; in Memoires de la Societe de Medecine de Montpellier, 1816, partiv. p. 517. van Doeveren, H. H., Dissert, de Macroglossa, seu Linguae enormitate. Lugd. Batav., 1824; cum tabulis duobus. 8vo. 2156. If the tongue increase very much in bulk it protrudes over the jaw, and can only be brought back into ihe mouth with difficulty, or not at all. This evil is generally congenital; but the enlargement of the tongue is not at first considerable. Its fore part appears only between the lips, it projects in a mass'as it enlarges over the lower lip and jaw, and causes great deformity. By the hanging down of the fore part of the tongue the swelling becomes larger, the tongue-bone and larynx are drawn forwards; there is great difficulty in swallowing, the spittle flows out, and from the constant dryness of the throat, swallowing becomes still more difficult. The articulation of the voice is greatly hindered; and when the disease has long continued, the muscles of the tongue are in a (a) WaI/Cher, above cited- TREATMENT OF ENLARGEMENT OF THE TONGUE. 383 palsied state. By the continued position of the tongue between the jaws the circulation is stopped in the protruded part, the tongue swells more considerably, and presses the teeth and the alveolar process of the lower jaw outwards; by the constant rubbing of the tongue indentations and excoriations are produced; the constant exposure of the protruded part to the air causes clefts and chinks, and often deep ulcerations; and the papille become unnaturally thick and prominent. 2157. The enlargement of the tongue takes places either a shorter or a longer time after birth, or after cutting the second set of teeth, and is fre- quently preceded by convulsions, and its cause seems to be palsy of the muscles of the tongue. In such cases the incisive and cuspid teeth are not pushed forwards, bnt are rendered useless, and fall out by the con- stant rubbing of the tongue (a). The enlargement of the tongue above mentioned must be distinguished from that protrusion which depends on inflammatory swelling, and from tumours of various kinds developed in the tongue. 2158. The congenital lengthening o/the tongue is of no great conse- quence; it is easily relieved if recent, and not incurable even when it have existed longer. The above-described symptoms accompanying this complaint when severe, especially its ill effects on nutrition, partly in regard to the difficulty of swallowing, and partly on account of the con- tinued loss of the saliva, render its early treatment necessary. 2159. The treatment varies according as the disease is congenital, or as it has occurred after birth ; and in the former case, with reference to the length of time it has existed. Soon after birth it is generally sufficient to prevent the complaint increasing, to irritate that part of the tongue protruded between the lips with acrid powders, as pepper and the like, in order to induce the child to draw it back. If it be necessary to keep the tongue in the mouth, a bandage must be applied to keep the lower against the upper jaw. As the enlargement of the tongue is encouraged by sucking, a wet-nurse must be chosen whose nipple is large and long, so that the tongue may require less lengthening as the child sucks than with a short nipple, or the child must be fed with a pap-boat. In the interval, when the child is not sucking, it must be endeavoured to prevent the protrusion of the tongue by the means already directed. [Clanny (b) mentions the case of a boy five years old, on whom the tongue had begun to protrude within the first year, and at the former age had projected three inches; but was returned with difficulty, and the jaws kept together, as recom- mended by Lassus (c). The tongue was replaced in the mouth with much difficulty, and retained by keeping the jaws perfectly closed with a handkerchief passed round them, and over the crown of the head, for the period of five weeks.] 2160. If the enlargement of the tongue be so considerable that it can- not at once be brought back into the mouth, its size may often be gra- dually diminished by repeated application of astringent irritating remedies. Scarifications and leeches may, with this view, be useful, as well as moderate and gradually increasing pressure, by means of a roller or a little bag of linen. This compression of the tongue, in which the bandage (a) Boyer, Traite des Maladies Chirurgi- (c) Mem. de l'lnstit. National, vol. i. n. 1 cales et des Operations qui leur conviennent, an vi.; and in Medical and Physical Journal vol. vi. p. 385. vol. vup. 353. 1801. (b) Above cited, p. 3.17. 384 TREATMENT OF ENLARGEMENT OF THE TONGUE. must be frequently moistened with a stringent, and the patient kept on his back, is advantageous, if properly persevered in, oftentimes in very far advanced cases. When the tongue has been so far reduced that it can be brought back into the mouth, the jaws must be kept constantly closed by means of a bandage. If the surface of the tongue be dry^it must be moistened by frequent washing and fomentation (c). 2161. When the enlargement of the tongue is so considerable that no benefit is attained by the above treatment, and when by the long con- tinuance of the disease its fore part is changed in structure, there remains nothing but shortening itc length with the knife or with a ligature. 2162. The patient, seated on a chair, must have his head fixed by an assistant standing behind him, and his mouth kept open either with a cork inserted between his back teeth, or by means of a speculum oris. The patient then protrudes and retracts his tongue, so that the operator may decide how much shall be removed. The tongue being protruded, is held by an assistant obliquely upwards with a pair ofpolypus or curved oesophagus forceps. The.operator then grasps the front of the tongue with his fingers, or fixes it with a hook; and with a strong bistoury cuts off some lines of the tongue in a semilunar shape, at a stroke. The forceps serve as a tourniquet, and the bleeding is stanched either by ligature, by the actual cautery, or by pressure and styptics. Where the state of the tongue permits, it is best, according to Percy (b), to cut out, by the strokes of the knife, a j\ shaped piece, with its point backwards, and after stanching the bleeding to bring the wound together with the interrupted suture. If, after the operation, the lower incisive teeth project considerably, attempts must be made, by continued pressure, to put them back; and if this should be un- successful, they must be drawn. If the lower lip continue everted and much out- spread, so that the spittle cannot be retained, a triangular piece must be cut out as in the operation for cancer of the lip, and the wound healed by the twisted suture (Mirault.) The application of a ligature for the removal of part of the tongue, in which the ligature is at once tied round it, or for the purpose of hastening its cutting through, a double thread is passed with a needle into the tongue, and the ends tied on each side, and gradually tightened, till the tied part dies, is attended with greater pain, and is more tedious than cutting it off with the knife, but is more safe against bleeding. [Harris (c) of Philadelphia tried to remove a portion of enlarged tongue, by introducing with a needle a double iron wire through the middle of the tongue, and having separated the two portions of wire, he brought them across the tongue, passed the two ends of each through a corresponding double canula on each side, and then twisted them ; the circulation ceased, but only for two hours. He then passed a strong silk ligature, and fastened it in the same way; but in forty-eight hours the circulation had returned. He therefore amputated the tongue with a catlin, through the track made by the ligature; the two principal arteries were tied at once, and other three, which had been allowed to bleed, to diminish the irritation caused by the previous ligatures, were taken up afterwards. The wound was dressed with dry lint, and the patient recovered perfectly, with the exception of a slight lisp in her speech. Harris, therefore, strongly recommends amputation, in preference to the ligature.] 2163. The protrusion of the tongue dependent on paralysis of its muscles, requires, besides the constant retraction of the tongue, blisters behind the ears, and on the neck, the application of irritants, of electri- city, galvanism, and the like. (st) Bo.yeR;, above eitcd^ p., 387., (c) American Journal of Medical Sciences, \h) AboxQ cUeoY vol. vii.. p. 1. 1830, and vol. xx. p. 17. 1837. BRONCHOCELE. 385- II.—OF BRONCHOCELE. (Bronchocele, Struma, Lat.; Kropf, Germ.; Goitre, Fr.) Haller, De Strumes; in Opusc. Pathol., p. 16. White, Thomas, A Treatise on Struma or Scrofula. London, 1784. 8vp. Ackermann, J. F., Ueber die Cretinen eine besondere Menschenabart in den Alpen. Gotha, 1790. Fodere, Traite du Goitre et du Cretinisme, &c. Paris, an vm. 8vo. Wichmann's Ideen zur Diagnostik, vol. i. p. 99. Gautieri, Tyroliensium, Corynthiorum Styriprumque Struma. Viennae, 1794. Wenzel, J. and K., Ueber den Cretinismus. Wien, 1800. Maas, Dissert, de Glandula Thyreoidea tam sana, quam morbosa, eademque im- primis Strumosa. Wirceb., 1810. Hausleutner, Ueber Erkenntniss, Natur und Heilung des Kropfes; in Horn's Archiv., vol. xiii. 1813. von Walther, P., Neue Heilart des Kropfes, u. s. w. Sulzbach, 1817. Burns, Allan, Observations on the Surgical Anatomy of the Head and Neck. Glasgow, 1811. 8vo. Huhlibach, Der Kropf nach seiner Ursache, Verhiitung und Heilung. Wien, 1822. Hedenus, Tractatus de Glandula Thyreoidea. tam sana, quam morbosa, imprimis de Struma, ejusque causis et medela. Lipsiae, 1822. Prosser, Thomas, An Account and Method of Cure of the Bronchocele or Derby Neck. London, 1771. 8vo. Wilmer, B., Cases and Observations in Surgery, with a Method of curing Bron- chocele in Coventry. London, 1779. 8vo. Barton, B. Smith, M.D., A Memoir concerning the Disease called Goitre, as it prevails in different parts'of North America. Philadelphia, 1800. 8vo. Holbrook, James, Practical Observations on Hydrocele; also on Bronchocele,&c, London, 1825. 8vo. M'Clellan, Inquiry into the Nature and Causes of Goitre, from a work on the Geology of Kemaon, Calcutta, 1835; and republished in Dublin Journal of Medical Science, vol. xi. p. 295. 1837. Inglis, James, M.D., A Treatise on English Bronchocele, with a few Remarks on the Use of Iodine and its Compounds. London, 1838. 8vo. Copland, James, M.D., Article Bronchocele,- in his Dictionary of Practical Medi- cine, vol. i. p. 269. [Gibson, W., Remarks on Bronchocele, in Philadelphia Journal of the Med. Sci., vol i. 1820.—g.w. n.] 2164. Bronchocele is a chronic, painless, more quickly or slowly arising swelling on the fore and under part of the neck, depending on enlargement of the thyroid gland, and varying considerably in reference to its extent, form, and hardness. The swelling begins in one or other lobe, or affects the whole gland, and may attain an enormous size; in most cases it has a pendulous shape. At first the skin is unchanged; as the growth increases, the veins in the neck and on the tumour swell and become varicose. If continuing still longer, the swelling usually feels elastic, soft, and regular; but after a further time, becomes firmer, and in some parts quite hard and uneven. Sometimes the swelling is so firmly connected with the neighbouring parts, that it is little or not at all moveable. If left alone, the bronchocele continues increasing; but in rare cases runs on to inflammation or suppuration, by which it diminishes, or entirely disappears. By the above description of bronchocele, its distinction into true and false, by which latter term various swellings in other parts of the neck have been described, is got rid of. 33* » 386 KINDS OF BRONCHOCELE ; TREATMENT. 2165. So long as the bronchocele is not large, it causes little or no inconvenience; but with its increasing size, the voice gradually becomes hoarser, the swallowing and breathing difficult, and there are severe fits of coughing. These symptoms increase in correspondence with the greater enlargement of the swelling, till there is danger of suffocation; in consequence of the obstructed circulation in the vessels of the neck, the blood collects in the vessels of the head ; the face becomes puffy and bluish, the patient complains of headach, and apoplectic symptoms may ensue. Owing to the disturbed breathing, and thejess expansion of the chest, the circulation through the lungs is interfered with, the obstacle which the arteries suffer to the impulse of blood given by the heart is increased, the cavities of the heart expand, and their walls thin; and hence arises the frequent enlargement of the heart observed in bron- chocele (a). 2166. Various kinds of bronchocele must be distinguished according to the variety of degeneration of the thyroid gland, which accompany its enlargement, namely, the vascular^ the lymphatic, and the scirrhous bronchocele. The designation of an inflammatory swelling of the thy- roid gland, {Cynanche thyreoidea,) as inflammatory bronchocele, is im- proper. Inflammation of the thyroid gland, which may be caused by cold external violence, and the like, produces, on account of its quickly-arising swelling, considerable dif- ficulty in breathing and swallowing, determination to the head, rushing in the ears, disposition to bleeding from the nose, and the like, and is usually accompanied with fever. If it run on to suppuration, the abscess does not protrude much, and the collection of pus, with increase of the above inconveniences, may become very considerable. The treatment of inflamed thyroid gland requires blood-letting, leeches in great number on the sides of the neck, calomel, and the like. If an abscess form, it must be opened as soon as the presence of pus is ascertained. 2167. In Vascular or Aneurysmatic Bronchocele {Struma vasculosa, aneurysmatica) the vessels of the thyroid gland, arteries, veins, and capillary vessels, which, with cellular tissue, make up the greater part of its parenchyma, become considerably enlarged. The kind of broncho- cele is characterized by its sudden origin, its quick growth, and large size. The swelling is warm, firm, and tense; the patient feels in it a violent beating, sometimes a roaring. If the hand be applied, the beating of the arteries is felt at some one part of its external surface, but espe- cially in the course of the large arteries in the substance of the gland; even the superficial twigs and branches are so much enlarged that they are seen through the general coverings, and their pulsation is distinctly perceptible. The superior thyroideal artery, before it enters the sub- stance of the gland, is felt beating violently, if the gland be not so very much enlarged that it cover this artery and spread over it with its upper outer lobe. Vascular bronchocele produces, earlier than any other, dif- ficulty of breathing and swallowing, frequent bleeding from the nose, dizziness, and determination to the head; it constantly increases. 2168. Lymphatic Bronchocele (Struma lymphatica) is of most frequent occurrence, and in many places endemic. The cells in the parenchyma of the thyroid gland become filled with a clammy transparent fluid, some- tfl) Lullier.—Winslow ; in Journal general'de Medecine, vol. Ivii. p. 414. 1816. VASCULAR AND LYMPHATIC BRONCHOCELE. 387 times with a viscid, brown mucous substance, sometimes with a lardy or cheesy mass, and sometimes with concretions and bony knob's. The walls of these cells thicken, often exceedingly, even to a cartilaginous consistence, become united with the masses collected in them, so that the cells are more or less completely destroyed, and the whole gland is converted into a shapeless mass. The vessels may, indeed, here also be enlarged, though not to the same degree as in vascular bronchocele. Lymphatic bronchocele increases more gradually, and feels more knobby. From this general sketch lymphatic bronchocele exhibits itself under as many forms, in reference to its external appearance, as it can present. Sometimes it shows a perfectly homogeneous, tolerable firm substance, without any yielding part, and resembles a sarcomatous degeneration. Sometimes its surface is irregular, several large knots are produced, hard, in several parts cartilaginous or bony. Sometimes particular cells enlarge, so that the greater part of the bronchocele consists of one or several cysts, the walls of which are more or less thickened and filled with fluid of different colour and consistence. This form of bronchocele was known to the ancients, (Celsus,) was described by Albucasis as Bronchocele aquosa, was variously noticed by Helwig, Heister, and Ploucquet, and has been fully described by Maunoir (a) as Hydrocele Colli. Percy would have it named Hydro-Bronchocele, and Beck (b) has described it as Struma cystica. The swelling developes itself on the fore part of the neck, on one or other side, sometimes on both at once, in which case there are often two lobes, with a consi- derable depression in the mesial line. It generally affords distinct fluctuation at every part, is opaque, but sometimes so transparent that the cysts and fluid contained in the deep-lying blood-vessels can be distinguished through the coverings (Pelle- tan.) Its size is very various, and it may become so large that the breathing may be rendered very difficult or completely stopped. Its cavities are frequently divided by a partition which is open at some one part, so that the two sides of the swelling communicate with each other. The cysts, which are almost always very thick, resistant, and little contractile, usually contain a brownish-coloured fluid; the other parts are very different. Opinions vary as to the actual seat of the swelling. Some say it is developed at the expense of the thyroid gland; others in the tissue surrounding the gland, in which case the gland, pressed back towards the windpipe, becomes atrophic, and is more or less surrounded with a false membrane, and the cyst is placed at its hinder upper part. If the swelling be developed in the gland itself, there are very rarely found any traces of its parenchyma, the vessels alone remain, and are filled with fluid which has usually the colour of wine lees. That the thyroid gland usually remains sound in this disease, as has been also supposed, appears without founda- tion; and according to the above-described, ordinary relations of the gland, its de- termination as a peculiar kind of lymphatic bronchocele is legitimate. It is charac- terized by its egg-shaped or globe-like form, without knobby elevations, by the elastic tension of the most projecting part of the swelling, by the bulging of its contents in different directions on the application of pressure which is not painful, by its more or less distinct fluctuation, and its transparency when present. The beating of the arteries is less distinct, and if present, as Dupuytren has noticed in one case, there is a motion and heaving of the swelling by the communicated pulsa- tion, and not depending on its expansion and contraction (Pigne.) [Under the one term, lymphatic bronchocele, Chelius here includes two decidedly different diseases; first, cysts in the substance of the gland, which he has described in the principal clause of the paragraph, may fairly retain the name; and, secondly, serous cysts in the neck, which are called by Maunoir, Hydrocele du Cou, but in reality are only cysts developed in the cellular tissue, and have nothing to do with the thyroid gland, except spreading over it as over the other parts in the neck; they will be again noticed in treating of Encysted Tumours, (p. 695.)—j. f. s.] (a) Memoires sur les Amputations, p. 93. Geneve, 1825. (6) Ueber den Kropf. Freiburg, 1833. 388 SCIRRHOUS BRONCHOCELE. 2169. In Scirrhous Bronchocele {Struma scirrhosa) the thyroid gland is less enlarged, but unusually hard, knobby, and irregular; the neigh- bouring cellular tissue wastes; from the very first the pain is violent and gnawing, and spreads up the neck; breathing and swallowing are very difficult, the one more than the other however, according to the part of the gland diseased. The scirrhous mass very soon adheres to the air- tube and to the muscles of the neck, and in the last stages the coverings become wrinkled and in folds. A sanious fluid often collects in the cells, immediately beneath the surface; the mass of the swelling presses backwards, by which the inconveniences .are very much increased. At last it is converted into a carcinoma and a *rue cancerous ulcer, with which the neighbouring glands of the neck become swollen. 2170. Much uncertainty prevails as to the cause of bronchocele. In many districts, especially in low valleys, it is an endemic, unless its cause can be decidedly referred to the state of the atmosphere, the use of water containing salts of difficult solution, or of snow water (1). Cretinism and bronchocele do not stand in -any necessary causal relation; the intel- lectual faculties are weak from birth in cretins, and in.many this blunt- ness of intellect is complete, without swelling of the thyroid gland, at least without any such as can produce obstruction to the circulation. Experience, however, shows in most cases in cretins a peculiar misforma- tion of the skull, by which the circulation in the carotids is more or less disturbed, and the enlargement of the thyroid gland produced by the greater inflow of blood (2). Females are more commonly subject to bronchocele than males, and its commencement usually begins with the menstrual development (3). Bronchocele frequently makes its appear- ance in scrofulous subjects (4). I have twice noticed congenital swell- ing of the thyroid gland. Violent exertion, labour pains, carrying heavy weights upon the head, screaming, and the like, frequently produce it, and sometimes very quickly. Walther supposes, that in aneurysmatic bronchocele the arterial system is always in a somewhat diseased condi- tion, and has a greater or less degree of aneurysmal diathesis. Of late the opinion advanced by Bordeu, of a closure of the tracheo-thyroideal passage as the cause of bronchocele, has been revived. [(1) That the cause of bronchocele depends on the mineral substances contained in the waters of the districts where it is common, appears to be proved beyond all doubt by M'Clellan's observations (a), and he seems to think probably also on the state of the atmosphere. He refers to the observations of Saunders (b) on the fre- quency of goitre in Sumatra, in proof that snow water is not the cause of this dis- ease, and he shows that it really depends upon the changed condition of the water which has circulated through the caverns of" the Alpine or compact limestone, and although not percolating the rock itself, has acted upon the extraneous fossils and metallic substances with which such rocks abound, and become impregnated with them,. He observes, that "Alpine limestone, does not occur to any great extent in the mountains of Ireland, nor in those of Scotland and Wales; and in these countries goitre is unknown. In England the disease is known by the name of Derbyshire Neck, and is principally confined to Derbyshire, where the particular rock in ques- tion forms the characteristic features of the county. In the Alps of Switzerland and Tyrol, where goitre and cretinism both prevail, we have the authority of geologists that Alpine limestone and nagefiugh (usually composed of fragments of limestone more or less rounded, and of various magnitudes, cemented together by a basis of calc-sinter, Jameson) compose the greatest portion of the mountains. Now this nagelflugh is of the same rock, or nearly so, as that on which the villages of Gose- (a) Above cited. (b) Journey to Boutan ; in Phil. Trans., vol. Ixxix. p. 89. 1789. CAUSES OF BRONCHOCELE. 389 ragong, Batuda, and Deota, are erected, villages whose inhabitants are affected with goitre to the extent of half their population." (p. 318.) In regard to the condition of the atmosphere as exciting this disease, he says :—" As this volatile poison (car- bonic acid gas) exists in limestone to the extent of 44 parts in 100 of the solid rock, it is possible to conceive, that a sufficient quantity of it, to cause a more or less vitiated condition of the air may be extricated from limestone by atmospheric heat, assisted by such other causes as promote the decomposition of the rock. * * * A reference to the mineral topography of all the villages in Kemaon, which I have examined, but one, seems to favour rather than negative these views. * * * If there be difficulties in the way of conceiving the possibility of the emission of car- bonic acid gas from limestone, its absorption by lime water may be suggested as a means by which it may be attracted by the moisture on the surface and at the base of calcareous mountains." (p. 321.) (2) M'Clellan observes on this point:—" From goitre as it appears in Kemaon, in its more distinct form, as well as in conjuction with cretinism, there are many reasons for believing that both complaints are intimately connected with each other; if not identically the same, they are mere modifications of different degrees of inten- sity of the same causes." (p. 335.) (3) According to M'Clellan, "the disease begins at any period of life after the age of three years, and never as far as he has seen, arrives at its full size sooner than six years from the time of its commencement, btft is generally much slower, its progressive augmentation seldom however becoming perfectly suspended during a residence in an affected village. * * * The usual size of a full grown goitre is about one foot ten inches in circumference, including the neck; and about two feet from one angle of the lower jaw to the opposite side, measuring under the tumour." (p. 317.) Inglis (a) says as to the age at which bronchocele is most usual:—" We may infer that the first ten years of life are comparatively exempt from the disease, and that the second ten are most subject to it; as out of one hundred and eleven, only eleven appear during the first ten, sixty-three during the second, and twenty-four in the following; the fourth ten years present four cases, the succeeding, four; and from the age of fifty to sixty-two only two cases are found." (p. 57.) Dr. Copland also observes that in a considerable number of cases which have come before him in females, he has never met with any before the period of commencing puberty." Inglis has also compared the proportion of cases in this country, which have been collected by several writers, from which it appears that, in a hundred cases, those observed in men varied between two and five and a half per cent. (p. 32.) (4) Dr. Robertson indeed says:—" There are many reasons to induce us to regard goitre as a particular variety of scrofula; in this country (England) it is only seen in highly scrofulous constitutions." As to the differences between sorofula and bronchocele stated by Postiglione (b), M'Clellan denies that the latter should be considered a merely local disease, or that it begins at a later period than scrofula and does not spontaneously disappear; but he admits that scrofulous glands often sup- purate, whilst bronchocele rarely undergoes this change, which he considers the only real distinction between the two. From " the consideration of the predisposing cause," however, he observes, we are led to the conclusion " that the same inherent diathesis, that under certain circumstances gives rise to scrofula, would, under exposure to the ex- citing cause of goitre, occasion that peculiar form of disease." (pp. 339, 40.)] 2171. The size, duration, and nature of the disease, must be taken into the account as regards the prognosis in bronchocele. Small lymphatic bronchoceles in persons under twenty-four years of age are commonly soon cured. But the cure is more tedious if the swelling be larger and firmer and in older people. In large bronchoceles both internal and external employment of medicinal remedies are frequently useless, and a decidedly operative treatment must be employed to get rid of the swell- ing entirely, or at least to diminish it to such degree that the patient's sufferings may be bearable. The carcinomatous degeneration of the (a) Above cited. (b) Memoria Patologico practica sulla Natura di Gozzo. Firenze, 1811. 12mo. 390 BRONCHOCELE, TREATMENT OF. thyroid glandis incurable. In rare cases, bronchocele, when consequent on severe violence, cold and the like, may be attacked with more or less violent inflammation {Thyreophyma acutum) of Frank (a), in which case, with pain, increased heat, and sometimes with redness of the bron- chocele, its tension and size quickly and considerably increase; the arte- ries of the neck pulsate strongly, the veins swell, there is difficulty in breathing and swallowing, determination to the head, redness and puffi- ness of the face, and frequently considerable fever. This inflammation may run to suppuration; the bronchocele may be completely or in great part destroyed ; the collected pus, if the abscess be not opened in proper time may produce, by burrowing, considerable destruction of the neigh- bouring parts, may eat away even the air-tube itself and empty into it {b). 2172. The treatment of bronchocele must vary according to the nature of the swelling, as the remedies applicable to one form of the complaint, are of no use in another. 2173. In vascular bronchocele, the further growth of the tumour can alone be prevented and its diminution effected, at the very first, by general and local blood-letting, by the patient at the same time keeping perfectly quiet; by the continued employment of cold applications, and the internal use of digitalis, and by carefully avoiding every exertion; at least, I have in two cases followed this practice with success. If the vascular bronchocele have already attained considerable size, nothing is of any service, and the proper remedy for diminishing, if not of perfectly getting rid of the swelling, by which the inconveniences it causes are also removed, consists in tying the superior thyroideal artery, by which the thyroid gland is deprived of the greatest quantity of the blood which flows into it. 2174. This Operation was first proposed, in way of question, by Charles G. Lange (c), afterwards by Jones {d), especially applied by Spangenberg to aneurysmal bronchocele, and first undertaken by Wil- liam Blizard (e), in whose cases great diminution of the size of the swell- ing ensued, but the patient died of hospital-gangrene. Walther (f) performed the operation successfully ; also Coates (g), Wedemeyer (h), Jameson {i), Earle (j), Beck {k), and I, myself, in six instances. Fritze {1), Zang (m), and Langenbeck (n) have met with fatal cases (a) De curandis hominum morbis Epito- (/) Above cited, in his Journal fur Chi- me, lib. vi. pais ii. p. lxxx.—Hupeden, Diss, rurgie und Augenheilkundc, vol. ii. p. 584. sistens Animadversiones de affectionibus in- ig) Med-Chir. Tr.ms., vol. x.p. 312. Ibl9. flammatoriis Glandulae Thyroidea). Got- (A) Langenbeck's Neue Bibliothek, vol. tings, 1824. iii. part. ii. p. 185. (6) Baillie, Matthew, M.D., a Series of (i) American Medical Recorder, vol. v. p. Engravings, with Explanations, intended to 116. Ib22. illustrate the Morbid Anatomy of some of (j) London Medical and PhysicalJournal, the mosi important parts of the Human vol. lvi. p. 201. Sept. Ib26. Body. SfCO"d Edition. London, 1812. 4to. (&) Above cited. (c) Dissertatio de Strumis et Scrophulis, (l) Hedencs, above cited, p. 255. p. 16. Witernb., 1707. (m) VerunoliickterV. rswh, eine Kropfge- (d) A Treatise on the Process employed schwulst riurch TJnlerbindung der Arteria by Niturein suppressing the Haunorrhage thyreoidea superior zn heilen, Mitgttheilt from divided and punctured Arteries, and on van Dr. Horen; in Rust's Magazin, vol. vii. p. the use of ihe Ligature, &c. London, 1805. 315. 8vo. (n) Neue Bibliothek, vol. iv. part iii. p. (e) Allan Bukns, above cited, p. 203. 558. OPERATION OF TYING SUPERIOR THYROIDEAL ARTERY. 391 from bleeding, and inflammatory symptoms. Graefe (a) and myself (b) have operated without any permanent result. 2175. Tying the superior thyroideal artery is performed in the following manner. The patient seated ou a high stool, opposite the light, in- clines his head to the contrary side on which the operator stands, and rests it on the breast of an assistant. At the point where the artery is felt pulsating, the skin having been moderately stretched to prevent any fold, a cut is to be made through it, which beginning a little below the angle of the lower jaw and rather to its outside, is carried inwards and downwards along the inner edge of the m. sterno*mastoideus; and a second cut divides the m. platysma myoides in the same direction, the blood which flows into the wound being sopped up by an assistant with a moist sponge. The tip of the left forefinger is passed into the wound to ascer- tain most accurately the situation of the artery. A director is then pushed into the cellular tissue, covering the artery and the tissue divided with the bistoury; after which, it must be endeavoured to isolate the vessel with the blunt end of the director, with the handle of the scalpel or with the finger; but the use of any cutting instrument is to be avoided. The artery having been laid bare is now brought a little up, and a single round liga- ture carried with Deschamps' needle about it, and tied with two single knots. The ends of the thread lying out of the wound are fixed with a piece of plaster, and the edges being brought together with strips of plaster, some wadding and a compress are applied, and the whole kept in place by a circular bandage. The laying bare of the artery is rendered easy by the upper edge of the bron- chocele raising it up considerably. If the m. omohyoidtus, as it passes above the artery, interfere with the isolation of the vessel, it may be advantageously cut through. It is easier to tie the artery between this muscle and its entrance into the gland than above it. I have, however, found, in one case in which I tied the artery above this muscle, that it was as easy as tying it below. A branch of the glosso- pharyngeal nerve, which lies close to the thyroid artery, must be taken care of, and drawn outwards. This also applies to the thyroideal veins, and the laryngeal branches of the thyroideal artery; the ligature is applied where this artery is already given off. Every spouting vessel must be taken up as the operation goes on. Various propositions have been made as to the mode of finding the superior thy- roideal artery, and the direction of the cut through the skin, and this step of the ope- ration has been subjected to as definite rules, as for finding arteries in other parts of the body According to Jameson and Zang, the cut through the skin should be be- gun on the middle of the lobe of the thyroid gland, near the upper edge of the thyroid cartilage, and continued for the length of two inches, according to Jameson, of one, towards the clavicle, von Walther and others fix for the beginning of the cut the space between the tongue-bone and the thyroid cartilage, from which it is to be continued three inches in length on the inner edge of the m. sterno-mastoideus, towards the breast-bone. According to Langenbeck and Bujalskv, it should be- gin immediately over the submaxillary gland, and be carried down in a straight line to the lower edge of the thyroid cartilage. All these rules are, however, precarious; the situation and course of the superior thyroideal artery vary so considerably ac- cording to the size and extension of the bronchocele in different directions, that any such determination of the beginning and extent of the wound through the skin, (a) Hedunus, above cited, p. 255. gen uber die Struma vascuIoSa, und die Un- (6) Weissflag, Dissert., Animadversiones terbindung der pberen SchildrUsen-Schlaga- de Struma aneurysmatica. rt de Arteriis dern; in Heidelberg, klinisch. Annalen, vol/ Glandule Thyroideoe Superioribus ligandfs. i. p. 208. Heidelb:, 1823. 4to.—Chklius, Bemerkun- 392 BRONCHOCELE | TYING OF SUPERIOR THYROIDEAL ARTERY. cannot in general apply, and the above-mentioned rules on this point can alone be held with. 2176. The patient having been put to bed, with his head a little raised and laid on the side, must be kept quiet and treated precisely as when an artery is tied for aneurysm. It seems in this case always advisable after the operation to have recourse to a not inconsiderable blood-letting, for the purpose of checking a great flow of blood to the brain. If inflamma- tory symptoms, difficulty of breathing and swallowing, headach, and the like, should occur, general and local blood-lettings are to be considered the most efficient remedies. Violent cough requires extract of hyoscy- amus, together with antiphlogistic means. If both superior thyroideal arteries require tying, that of the other side must be tied after the wound of the first operation have healed. After tying, the bronchocele loses its elastic feel, the pulsation di- minishes, the warmth lessens, and the swelling becomes smaller and shrivelled. 2177. If this operation be compared with those modes of treatment formerly recommended in that stage of bronchocele which threatens danger, as extirpation of the thyroid gland, the introduction of a seton, or issues, it must undoubtedly be preferred, partly on account of its easy performance, and partly for its happy result, when the bronchocele is of the vascular kind, that is, depending more on the enlargement of the ves- sels than on the thickening of the uninjectable part of its tissue, or on the pouring out of lymph-clots and degenerations in its cells. If the growth of the bronchocele cannot be in any way prevented, dangerous symptoms may be produced, and the superior thyroideal artery felt pulsating dis- tinctly. A slight degree of still little developed general affection of the vessels accompanying aneurysmal bronchocele must not contraindicate the operation ; but in far advanced diseased alteration of the heart and arte- rial system, those ill consequences at least may accrue after the operation, which happen after the operation for aneurysm, when there is an aneu- rysmal diathesis (1). If these circumstances be carefully considered be- fore the operation, and that performed with due caution, the results, in most cases, correspond with our expectations. To this must be added that aneurysmal struma, as above mentioned, {par. 2167,) is not common; that the symptoms maybe illusory, since the bronchocele characterized as aneurysmal, exhibits in its interior more or less thickening, cavities and cells rilled with serous or brownish fluid, and that such bronchocele may also be efficiently treated with seton (a); hence the propriety of tying the superior thyroideal artery is not disparaged. von Walther doubts the possibility of the growth of the tumour after tying the superior thyroideal artery, and asserts the adhesion of a very large portion of the expanded and tied vessel. I have, however, noticed the contrary, as the growth of the swelling may be continued by the en- largement of the inferior thyroideal artery and its communication with the superior (2). In general this does not happen, and perhaps can only, when the inferior as well as the superior artery is at the same time enlarged {b.) It must, however, be always remembered, in deciding (a) Rusts' Magazin, above cited.—Langenbeck, above cited. (i) Chelius, above cited, p. 233; and in Heidelb. klinish. Annalen, vol. i. part i. TREATMENT OF LYMPHATIC BRONCHOCELE. 393 on tying the superior thyroideal artery, that if it be much enlarged by disease, the ligature will not effect its obliteration, but bleeding must ensue, which in many instances will have an unhappy result. (1) P. von Walther (a) has successfully practised tying the superior thyroideal artery as above directed in a case of aneurysmal struma. [(2) In confirmation of Chelius's statement regarding the growth of the broncho- cele, after tying the superior thyroideal artery, although the swelling had at first de- creased even considerably, Crawford (b) states that Coates informed him as to the final result of his operation above mentioned, "though the case proceeded extremely well for some time after the patient was discharged and lost sight of, yet the tumour subsequently, he understood, enlarged, and in the end destroyed the woman by suffocation." Also, in a case of Wickham's of Winchester, the largest he ever saw, " after the ligature of the artery, the swelling gradually diminished for about six weeks, after which it as gradually regained its former size. It seemed that the decrease of the tumour continued so long as the part of the gland, which had been supplied by the vessel, remained without nourishment; but as soon as the supply was restored by the anastomosing branches from the opposite superior and the two inferior thyroideal arteries, the swelling returned to its former dimensions. Such, I should conceive, would be the case unless all the thyroideal arteries were obliterated, which it would be a very difficult task to accomplish, if not altogether impracticable from the depth of the lower vessel." (p. 3--J1.)] The circumstances above noticed in regard to the enlargement of the inferior thyroideal artery has led to the proposal of tying it also. Velpeau (c), Die- trich (d), and Laymann (e) have given special directions for finding this artery. There may be cases in which after tying the superior thyroideal artery, the broncho- cele does not properly decrease, on account of the existing enlargement of the inferior thyroideal artery. But as regards the mode of tying the latter vesel, that which has been already mentioned as to the direction of the cut for tying the superior artery, applies to it also. Only if the inferior thyroideal can be decidedly distinguished, by its pulsation and size at the lower part of the bronchocele, may it be decided to tie it, and the direction of the cut must then be decided by the situation of the vessel. In a case in which I had tied the superior thyroideal artery and the bronchocele had diminished considerably, I felt the inferior artery pulsate distinctly, and could have undertaken tying it with ease, if the diminution of the swelling and the subsidence of the previous symptoms had not rendered it unnecessary. 2178. Lymphatic bronchocele, if not exceedingly large, and of very long duration may be always cured by the use of internal and external remedies, or at least be so far controlled, that the disease produces no serious inconvenience. 2179. Of all the remedies which have been employed internally for bronchocele, burnt sponge has been most used. It has been given in different forms, and with various combinations; but according to my experience most advantageously with red foxglove. Iodine, which is con- sidered the most important element in the burnt sponge, has, from Coin- det's. (f) experience and recommendation acquired great repute. Forty- fa) In his Journal fur Chirurgie und Au- genheilkunde, vol. ii. p. 584. Bulletin de la Societe Anatomique, nal, vol. xxiii. p. 257. 1825. Sept'. 1835, p. 12. y TREATMENT. 401 frequently in women than in men. Or warts are thick, have a broad base, and situated more deeply in the skin; their form is conical or cylindrical; they are immoveable and hard, outspreading on their top ; and the skin about their base seems burst through, as by the eruption of the wart, and its colour is completely changed ; the top of the wart is almost insensible, but frequently it is very painful within. [Besides the warts here mentioned, the generative organs are frequently attacked with two kinds, one of which has much the appearance of the " seedy wart," as it is commonly called, on other parts of the body, and is a very common attendant on gonorrhceal discharge, which has been allowed to remain on the skin and irritate it. At first this kind of wart has a little pedicle, with, in comparison to its size, a broad head, consisting of little flat prolongations, like the tips of leaves closely set toge- ther; from this there is an acrid secretion which is contagious, and wherever it rests, produces in the same individual, or in another having commerce with her or him, the same growth. The neighbouring parts soon become contaminated ; and it is not unfrequent to see the whole of the external female organs thickly covered with them, as also the glans penis of the male; and should there chance to be in the latter, phimosis, the warty growths rapidly increase, and distend the prepuce, till at last it bursts, and their protrusion gives the glans a cauliflower-like appearance. The other kind of venereal wart has not the narrow neck nor the leaf-like head, but is broad- based, not unfrequently sore, and sometimes even having somewhat the character of a shallow badly-skinned ulcer; this form more commonly is noticed when there are—or have been—sores, having a very chancrous character; and are often observed to exist when decided syphilitic eruptions cover the body. Warts sometimes take on a malignant character, and affect the neighbouring glands, and occasionally they seem to have a malignant character from the very first. I have seen them upon the back of the hand and on other parts of the body; they gene- ally have a broad base and a sort of cauliflower surface, and spread by enlargement of their base; sometimes they are tender and painful, at other times, not so; their head breaks off easily and bleeds freely, and sometimes, ulcerates, still, however, retaining the same warty character.—j. f. s.] 2192. The causes of wartis are, for the most part, unknown: local in- fluences, as pressure, blows, chafing, and the like, frequently seem to produce them; their foundation, however, is, in general, constitutional as they are produced in great numbers in certain persons, and especially on different parts, without any local influence being discovered ; and they recur after having been removed by local remedies. The blood may be in such state that where it touches the skin it may produce warts. 2193. In treating warts it must first be considered whether they de- pend on any decided internal cause or not, in order to employ the pro- per opposite remedies. Besides attention to diet, mercurial remedies, soap, fluid extracts, and resins, are recommended. In using these means, the warts often of themselves, or by the application of external remedies at the same time, waste away. Frequently also, at the period of puberty, they drop off" without any assistance. 2194. The external remedies advised for treating warts are very numerous; but they are all alike, in that they may be destroyed by caustic, or removed by tying, or the knife. To the caustics belong the juice of euphorbium, hemlock, sedum acre, strong acetic acid, tincture of cantharides, caustic ammonia, sulphuric acid, hydrochloric acid, butyr of antimony, lunar caustic, and tlie like, with which the wart is well to be touched; and this must be repeated as often as the crust falls off till the wart is completely destroyed. These remedies are especially appli- cable, if the wart have a broad base. If it have a neck, it may be tied 402 CALLOSITIES AND CORNS. with a thread, which must be tightened daily ; or it may be cut off with a knife. If the wart be thick, it is best to remove part with the knife, and destroy the remainder with caustic. It must not be forgotten, how- ever, that in thus treating warts, unhealthy sores are often produced, and that the scars, after using caustic, are more disfiguring than the previous warts. Warts which are very hard, irregular on their surface, and very painful, disallow the above modes of treatment; and if any thing be done, their complete removal, without leaving any of the degeneration, together with the proper remedies for any general disease connected with them, must be employed. [Common warts, when occurring, as they frequently do, in children, in large numbers upon the fingers and hands, often disappear with as little apparent cause as they have originated, and frequently, in a very short time. I do not think much advantage is gained by teasing them with any application; for they are rarely cured more quickly than if left alone. When, however, there be a single one or two upon the neck, or on the edge of the eyelid, or on the lid itself, it may be as well either to snip it off with scissors, or to tie it with a thin thread; and this more especially in adults. If a common wart have, as it has occasionally, a very broad base, attempts to remove it, by destroying with strong acids, will now and then set up inflammation of the absorbents; and when this has been checked, and the destroyed wart sloughed out, the scar takes on again the same disposition, and the wart is reproduced; it may become of larger size than before, of which I have had personal experience. Gonorrhceal warts, if few and distinct, may be snipped off^ and the wound touched with caustic potash; but if very numerous and close set, so that this cannot be done, they must be thoroughly destroyed piecemeal, either with caustic potash or nitric acid ; but before leaving the patient, it will be proper to neutralize the application with acid or alkali, as the case may be, or a troublesome, sloughy, and often un- manageable sore, will be the consequence. Whilst these warts are small and short they may very frequently be removed, by strewing daily upon them equal parts of savine and sulphate of copper, powdered and well mixed together, the parts having been previously well cleaned and dried, and the collection of the gonorrhceal matter upon the skin prevented by strict attention to cleanliness. Fumigation with cinna- bar is often also very efficacious. The broad' warts, which seem to be truly syphi- litic, almost invariably disappear under a mercurial course. Malignant warts must be removed with the subjacent cellular tissue down to the muscle on which they are seated. The application of caustic only irritates, and quickens their growth.—j. f. s.] * V.—OF CALLOSITIES AND CORNS. (Indurationes et Clavi, Lat.; Schwielen undHuhneraugen, Germ.; Cars, Fr.) 2195. Callosities are more or less circumscribed thickenings of the epidermis, produced by continued pressure. They are most commonly seen on the backs of the toes, on their joints, especially on the last, and between the toes (corns.) They are generally flat, as if pressed into the skin, are produced slowly, and only when they have become large cause darting pain, una"er which circumstances the neighbouring parts are in- flamed by the pressure of the callous mass. Sometimes they commence with violent pain, especially in persons whose skin is tender. They are more troublesome in warm than in cold weather. The skin is indented in the middle of a corn, and on examination, the corion is often found perforated. These projections of the epidermis consist of two substances; the upper is dry, in shape like the head of a nail, and formed of layers of epidermis, one upon the other, HORNS. 403 which often readily separate from each other, especially if softened by bathing the feet. This substance shows no organization. The other part deeper and semi-trans- parent forms the base of the former, penetrates through the thickness of the skin down to the tendon, to the ligament, and even to the bone, upon which it is in a manner rooted, which shows it to have a certain degree of organization. Bresohet observed it to be penetrated in different directions by numerous vessels. It is this which especially causes the pain in changes of the weather, although that is also produced by the pressure of the horny substance upon the surrounding parts, in con- sequence of which inflammation of its whole extent ensues, and may even spread (Pigne.) The corn is, according to Brodie, in the beginning, a thickening of the epidermis as a consequence of greater secretion from the cutis from pressure; subse- quently a bursa forms; by degrees inflammation of this bursa takes place beneath the horny epidermis, in consequence of which it becomes very painful and runs on to abscess. Rosenbaum (a) explains the origin of this bursa as consequence of the closure of the glands of the skin. 2196. The cure of callosities and corns requires, above all things, the removal of pressure from tight shoes, and even from tight stockings ; after which they gradually subside of themselves. If the corn be upon the sole of the foot, a felt sole must be worn, with a hole in it, to receive the corn. As palliatives may be used, softening plasters, frequently bathing the feet, shaving off in slices, or scratching away with the knife, or with wetted pumice-stone, the application of a plaster, with a hole in its middle, into which the corn may be received. The complete removal of the corn, by dividing the skin around it with two cuts, lifting it up with forceps, and extirpating it with the knife or with scissors, which is always attended with considerable pain; also its destruction with caustic; and strewing it with different remedies, after previously removing some layers of the callous mass, are mere palliatives, if the cause, that is, pressure, be not removed. Some persons are more subject to corns than others. The numerous remedies recommended for corns are either softening plasters and salves, or irritating and caustic applications, which produce either inflammation, suppuration, and throwing out of the corn, .or its destruction. The latter remedies are objectionable, as they often produce violent inflammation, extensive suppuration, and danger of gangrene. Also in removing them by slices, care must be taken that neither pain nor bleeding arise; and the same also applies to the subsequent touch- ing with lunar caustic, (Wardrop,) with bals. vit.se Hoffm., with Unci, iodin. 3iv., ferri iodur. gr. xii., antim. mur. 3iv., (Henderson,) and the like, as thereby dan- gerous symptoms, especially in old and gouty persons, may be produced, and the radical cure thereby as little effected as by extirpation, if the pressure be not re- moved. I have witnessed dangerous consequences after such treatment, and agree with P. Franks' warning de clavis pedum caule secandis. VI.—OF HORNS. (Cornua, Excrescentiae Cutis, Corneae, Rhinodysmorphia corniculatai Lat.; Hornartige Jluswiichse, Germ., Comes, Fr.) Journal de Medecine, Chirurgie et Pharmacie de "VanderMonde, vol. xiv. 1761. Rudolphi, Ueber Hornbildungen; in Abhandlungen der Berliner Akademie^ 1814-15. Ernst. Dissert, de Corneis humani corporis Excrescentiis. Berol., 1819. Westrumb ; in Horn's Archiv., 1828, p. 316. Froriep; in Casper's Wochenschrift, 1833, p. 412. Bulletin de la Societe Anatomique de Paris, 1835, pp. 98, 114, 13K (a) Allgemein Medic. Zeitung. 1838. No< 60, 404 HORNS. Landouzi, Memoire sur une Come humaine. Paris, 1836. Ainsworth, Dissert, de Corneis humani corporis Excrescentiis. Berol., 1836; cum tab. aeneis, iv. Wustefield ; in Casper's Wochenschrift, 1836, p. 635. Ebers ;------------------------------1837, p. 567. Steinhaeusen ; in von Graefe und von Walther's Journal, vol. xxiv. p. 141. Cruvelhier, Anatomie pathologique, livr. 20. 2197. Horny growths of the skin, and mucous membrane, often rise several inches above the surface of the skin, and have perfect resemblance to the horns of beasts. Usually there is only one, but sometimes several at once, or near together; many even are spread over the whole surface of the body, under which circumstances the disease seems to form the transition to elephantiasis, where a horny substance, in shape of scales or spines, coversthe whole lower partof the body. These horny growths occur upon the hairy parts of the head, upon the forehead, nose, and cheeks; upon the breast, back, shoulders, arms, and hands; at the beginning of the mucous membranes, and on other parts. Horns have been observed on the hairy part of the head by Fabricius ab Aqua- pendente, Bartholin, Gastellier, Lex, Home, Parkinson, Ansiaux, Piccinelli, Caldani, Astley Cooper, Testa, and by myself thrice ; on the nose by myself; on the hands and feet by Borelli, Lachmund, Dolceus, Dennis, Marc, Otto, Lages; on the thighs by Dumarceau and Carradois; on the face by Borelli, Riverius, Fournier, Vicq d'Azyr, Breschet, Wagner, Lorinser, A.Froriep; on the eyelids hy Voisin ; on the back and breast-bone, by Rig-al ; on the loins and buttocks by Cruvelhier and Rigal; on the lachrymal caruncle by Chavane; on the conjunctive coat, and on the tongue, by Breschet; on the red edge of the lip by Jaeger; on the inside^of the prepuce, on a scar, after the operation for phimosis, by Dieffenbach; on the glans penis by Reghellini, Bonioli, Caldani, Ebers, Richard-Destru, Breschet, and Meckel. For an account of the most important early obervations on such horny growth see Samuel Cooper (a). [Erasmus Wilson (b) has given an interesting statistical account of horns which have grown on the human body, having " succeeded in obtaining ninety cases; of which forty-four were females, and thirty-nine males; of the remainder the sex is not mentioned. Of this number forty-eight were seated on the head, four on the face, four on the nose, eleven on the thigh, three on the leg and foot, six on the back, five on the glans penis, and nine on the trunk of the body. The greater fre- quency of this disorder among females than males is admitted by all authors; but this fact is most conspicuously shown in the instance of the thigh and of the head; for example, of the eleven cases of horny growth from the thigh, two only were males; and of the forty-eight affecting the head, twenty-seven occurred in females, and nineteen in males; in the remaining two the sex being unmentioned. That old age is a predisposing cause of this affection, is proved by the greater frequency of its occurrence in elderly persons; thus, of forty-eight.cases in which the scalp was the seat of the growth, thirty-eight were above the mid period of life; several were over seventy, and one was ninety-seven; three were young persons, and three infants." (pp. 64, 65.) In the Museum at St. Thomas's Hospital there are three examples of horns from the human body, two of which are those referred to by Astley Cooper; the larger one, which is about ten inches long, with a base an inch in diameter, and tapering towards the tip; it grew on the upper part of a man's head, and is twisted towards its extremity somewhat like a ram's horn; it was removed, together with its root, by Dr. Roots, of Kingston-on-Thames, after a growth of seven years, and had been pre- ceded by one of three inches long, which had sprung up from the scar of a tumour, of what kind is not mentioned, which had been removed, and after growing four iyears, fell off, or probably was pushed off, as the patient was lifting his hat (a) First lines of surgery, p. 346. Edition of 1840. (b) Med-Chir. Trans., vol. xxvii. 1844. HORNS J THEIR CAUSE. 405 from his head; leaving "the surface from which it dropped," says Roots, "per- fectly smooth, and free from any discharge whatever. In a few months a new horn began to appear," &c. (p. 234) ; the horn is now in our Museum. The other horn, which Astley Cooper speaks of, was from the pubes, about an inch in length, conical, and three quarters broad at its base and of an oval shape. The third case was a patient of my own, who had two of these horns growing from the left side of the scrotum; one rather larger than the other, about the size of the little finger, and two-thirds of its length; one dropped off whilst he was in the house, leaving a sore surface; and I intended removing the other, but he took fright when it was proposed to him, and went away. The Museum of the Pathological Society of Dublin possesses two horns of considerable size, which grew for six years on the upper lip of a man about sixty years of age, and were removed by Pierce (a). In the Museum of the Royal College of Surgeons of England there are two very remarkable horns, which were purchased at the sale of Sir Ashton Lever's collect tion, and marked, "supposed to be excrescences from the human head," which is unfortunately all the history of them. That they are, however, human there can be no doubt, as on the larger one a few short hairs remain, which, on examination with the microscope, presented all the characters of human hair. They are conical and slightly contracted at their base, as if they had been girt somewhat by the aper- ture through which they protruded ; or as if a groove had been formed round them preparatory to falling off, as in the shedding of stags' horns. The larger is three and a half inches long, and the smaller only one and three quarters; but the greatest diameter of both is an inch and a quarter. The smaller one has been sawn through vertically and presents a solid bony core, surrounded by a brownish horny sub- stance, varying from one and a half to three lines in thickness, and so completely covering it, that all connexion between the core and any other bony part must have been impossible. The characters of the core, in all respects, even with the aid of the microscope, prove its semblance to healthy compact bone.] 2198. These horny growths are partial luxuriances of the epidermis, or of the mucous lining of an encysted tumour, when the horny substance is deposited in a sebaceous bag {tumor sebaceus). In the first case, they sometimes begin without any pain or decided cause, or after some sort of irritation, as a little elevation in the skin, with branny surface, with itch- ing, burning, or shooting. After the branny surface is thrown off, there appears a small, hard, more or less convex swelling, of a white or gray colour, which grows more or less quickly; in exact relation with its en- largement, it becomes harder, conical, shrivelled, twisted in a spiral shape exactly like a brute's horn, from one to twelve inches long, and several inches round, is hardest at the tip, grayish or dusky on the surface, rough, and sometimes covered with hairs. In the second case, a nail or horn-like substance is secreted in an encysted tumour, (tumor sebaceus,) which bursts the skin, hardens, and protrudes in proportion as more of the sub- stance is secreted by the tumour. When these growths have attained great size, or are periodical, at a certain time of year they are thrown off", and for the most part recur, or leave ulcers behind them. [Of the mode in which these horns are formed from a previously obstructed fol- licle, Erasmus Wilson (b) has given a very good description, showing how the se- baceous accumulations may become converted into horn. He says:—"From the torpid action of the skin, or from the nature of the contents of the cells, or from both causes together, the sebaceous substance collects within the follicle, becomes im- pacted, and acquires an abnormal degree of density. In this situation the impacted mass exerts so great an amount of pressure on the vascular walls of the follicle as to abrogate its special function, and the peculiar elements of the sebaceous secretion, cease to be produced. The formation of epithelium, however, still continues, and (a) Dublin Journal of Medical Science, vol. xvi. p. 329) 1839, (6) Above cited* Vol. 111.-^35 406 HORNS ; THEIR CAUSE. layer after layer of epithelial scales are developed, until the mass acquires consider- able size. Tumours of this kind, from the nature of the position of the sebaceous follicle, namely, within the corium, rarely acquire a large size as compared with tumours in other situations. They are prevented from pressing inwards by the deep stratum of the corium ; the same structure opposes their increase outwardly or later- ally. Nevertheless, I have seen a tumour of this kind, which measured three quar- ters of an inch in diameter, but not more than a quarter of an inch in thickness. The aperture of the follicle remains open, and is more or less distended in proportion to the extent of the tumour; but from the nature of the collection, there is no ten- dency to its escape. I have called such tumours sebaceous accumulations. Certain minute tumours, commonly met with in clusters, around and upon the eyelids, sebaceous miliary tubercles, are of the same pathological nature with the sebaceous accumulations, but in these the excretory follicle is closed. The peculiar patholo- gical character of the tumours just described, is their laminated texture, and the identity of structure of their contents with epidermis, most, if not all, of the peculiar constituents of sebaceous substance being absent. * * * If now, in the cases above recited, we imagine the upper wall of the laminated tumour to be removed, and the accumulated substance exposed to the influence of the atmosphere, any moisture retained by the epithelial laminae would soon become dissipated, and the wholemass would acquire the consistence and hardness of epidermis of equal thickness; in other words, it would be converted into horn. Such a case as I am now supposing, does sometimes in reality occur. The aperture of the follicle acquires an unusual de- gree of dilatation, and some of the hardened contents of the tumour are pressed through the opening. By the addition of fresh layers from below, (the formative power having increased by the removal of superficial pressure,) the indurated mass is still further forced outwards, dilating the aperture as with a wedge, and finally increasing its size to that of the entire base of the hypertrophied follicle. The pro- cess of formation of new epithelial layers by the walls of the follicle (now become the base of the mass) will go on, unless interrupted by surgical means, for years, and in this manner those singular bodies, of which so many examples are on record, horns, are produced." (p. 57-59.)] 2199. The proximate cause of these growths is a perverse and in- creased secretion of the vascular net of the skin, of the mucous mem- branes, or of the internal surface of encysted tumours. They are most usually produced in persons of advanced age, and their immediate cause is continued irritation of the skin, or of the mucous membrane by kicks, blows, chafing, wounds, scars, eruptions on the skin, and the like; or they are in causal relation with suppressed menstruation, rheumatism, and gout, or rickets. Most cases, however, show that persons affected with these growths are in otherwise sound health; and even when they are thrown off, there is usually no disturbance of the constitution. Mercier (a) distinctly observed in a growth of this kind, which was an inch high and an inch and a half round its base, hard and dusky, from its base to its tip, that it was formed of fibres converging from the base to the tip, and which at bottom were separated by fat, so as to have the appearance of ordinary fibrous tissue. The fat diminished, and the fibres becoming closer towards the tip, were mostly grayish black, and extremely hard ; they were also less soft and white as they approached the surface. They were easily separated at the root, and were con- tinuous with the fibres of the skin, which from the fact of vessels being also present, led him to believe that they Were not true hairs, but merely a degeneration of the fibrous tissue. Mercier supposed it connected with the skin, and that its hardness depended on the evaporation of the fat and intermediate fluid. According to his notion, some horns are not the result of diseased secretion, but of actual transforma- tidn of the skin. Hairs may however exist in such horns, just as in encysted ewellings, \>ut the horn must not therefore be considered to be formed of conglo- meration of hair, as supposed by some persons* (a) Bullet, de la SocieW AnalomiqUe de Parh?. 1735, p. 114-131. BONY GROWTHS. 407 2200. Examination of these horny growths proves that their base is formed of a soft tumour, and their root usually, in mucous membranes more particularly, consists of a lardy, vascular tissue, similar to the matrix of a nail (Jaeger) ; upon this is a substance composed of parallel fibres, which increases in hardness and density near the surface and tip; the fibres are fewer towards the centre, and separated by a soft fatty mass, which is in greatest quantity at the root. The density and hard- ness of the growth are in direct relation with its dark colour; both are least in the middle and towards the base. These growths are held to be identical with the substance of nail, and the spurs of gallinaceous birds, which is confirmed by chemical examination, being composed of the same substances as the horns of beasts, excepting the antlers of deer, which contain more than a fourth of their weight of gelatine, and have oxygenated albumen as their principal element. Their colour, hardness, and transparency depend on the carbon, phosphate of lime, and glue-like substance which they contain (Jaeger.) 2201. In their treatment, their cause must be removed by proper remedies, preparations of antimony and quicksilver, by baths, decoctions of woods, Zittmann's decoction, and the like. It has been noticed that they drop off, under the use of purgatives. If this do not however happen, the sound skin must be divided by two semilunar cuts, and the horn with its root extirpated, in doing which every thing in and beneath the skin, which has degenerated, and is discoloured, or suspicious must be carefully removed. With this object it may be advisable even to cauterize the wound, so as to produce an issue, and to employ propey after-treatment. The merely cutting short these growths, by sawing or filing, in general causes their increased growth; and also tearing them out, when the connexion of their root is not very great, is objectionable on account of the pain and the uncertain results. VII.—OF BONY GROWTHS. (Tumores Ossium, Lat.; Knochenauswuchse, Germ.; Tumeurs des 6s, Fr.) Matani, Observationes de Ossium Tumoribus. Colon. 1765. Herrmann, Dissert, de Osteosteatomate. Lipsiee, 1767. Houstel, Sur les Exostoses des Os Cylindriques ; in Memoires de l'Academie- de Chirurgie,!/vol. iii. p. 130. Bonn, Tabula* Ossium Morbosorum, praecipue Thesauri Hoviani. Lugd. Batav., 1788. von Heekeren, De Osteagenesi praeternaturali. Lugd. Bat., 1797. Vollmar, Beobachtungen iiber die Knochenspechgesohwulst; in Loder's Journal5 fur die Chirurgie, u. s. w., vol. iii. p. 46. Boyer, Traite des Maladies Chirurgicales, vol. iii. p. 543. Otto, Seltene Beobachtungen zur Anatomie*. Physiologie und Pathologie zehorig. Breslau, 1816. Cooper, Astley, On Exostosis; in his and Travers's Surgical Essays, part k London, 1818. Third Edition. Pech, Osteosarcoma, ejusque speciei insignis descriptio, etc. Wirceb., 1819; Dietel, Comment. Anatom. Pathol, de Osteosteatomate. Lips., 1822. Miescher, De Inflammalione Ossium. Berol., 1836. 4to. Richter, A. L., Die Organischen Knochenkrankheiten. Berlin, i#39. [Gibson, W., The History and Treatment of Bony Tumours, in the Philadelphia Journal of the Med. Sci., vols, iii andUiu 1821.—a. w. n.] 408 KINDS OF BONY GROWTHS. Also the general observations on Diseases of Bone, by Petit, Duverney, Pallas, Boettcher, Bertrandi and Closius. 2202. Bony growths form swellings of greater or less extent, which arise from the surface or interior of the bone, and in which the texture of the bone either remains natural, or the enlarged bone becomes unusually firm, hard, ivory like, or loosened up, spongy, and partially converted into a fleshy or lardy mass. According to these various conditions are dis- tinguished true bony growths, (exostosis,) bone-flesh or bone-lard growths, {osteosarcoma, osteosteatoma,) and spina ventosa. 2203. These diseased changes of bone may originate in the periosteum, in the bony tissue itself, or in the medullary membrane. Their general origin is an inflammatory condition of the periosteum, of the medullary membrane, or of the membrane lining the bone-cells, which swell by the larger deposition of the juices, and secrete a plastic matter, which by the laws of the natural growth of bone, is converted into bony substance. Or there is an unnatural growth of the bony tissue, or there is produced in the cells, a fleshy, lard-like or gelatinous substance, which absorbs the mass of the bone, and converts it wholly or in great part into a lardy or fleshy substance. The causes exciting this inflammatory condition, are either external violence or dyscrasic diseases, especially syphilis, scrofula and gout. According to the chronic or acute character of this inflammation, and the variety of the causes on which it depends, does the course and issue of this diseased change of bone vary. 2204. True Exostosis (Exostosis proprie sic dicta, Lat.; eigentliche Knochenauswuchs, Germ.) is a more or less circumscribed tumour arising from a bone, and depending on an unnatural increase of the bony sub- stance. This tumour is sometimes confined to one part merely of the bone, and attached to it by a thin neck or by a broad base; at other times, it springs up without any definite boundary; and sometimes occupies the whole extent of the bone, under which circumstance in tubular bones, the medullary cavity is in general lessened, or completely destroyed. Some exostoses consist of a great development of the bony tissue itself, arise from he medullary membrane, or from the cellular structure of the bone; some form over its whole extent, between the bone itself and the periosteum. According to Jaeger (a), exostosis never arises from the interior substance of the bone, but. is attached firmly to its external surface; between it and the exostosis, a fine line of the shell of the bone forms the boundary; this is gradually absorbed, so that the cells of the exostosis are partially, or completely connected with those of the bone. But the exostosis which is developed between the periosteum and the bone, is oftentimes the consequence of a natural secretion of the bony tissue itself, and spreads from the interior towards the exterior of the bone. In this case the perios- teum is only secondarily changed, and the tumour seems like a wedge sunk into the substance of the bone, is co,mmonly hard, and like ivory. The substance of the mother bone is compact, hard and ivory-like to a greater or less depth. In other instances the tumour springs from the periosteum itself, in consequence of inflamma- tion of its substance; sometimes a plastic exudation takes place on its inner surface, which becomes bony at the same time, and in the same manner as in the natural formation of bone. Sometimes these deposits are separated by the internal plate of the periosteum, and are then more or less moveable upon the bone itself; at other times they are firmly attached to the bone, which itself exhibits no change. These axosioses. are generally cellular, and rarely ivory-like. They are not unfrequently (a) HandwOrterbucb, vol. ii. p. 507. EXOSTOSIS. 409 noticed at the seat of encysted tumours, which by their pressure have given rise to them. (Pigne.) 2205. The internal condition of exostosis varies; sometimes if the swelling be not large, and lie on the surface of the bone, a net-work of body fibres is observed, in the interspaces of which a new mass of bone is deposited; sometimes the interior of the swelling presents rather a laminated structure, sometimes the hardness of the exostosis is- greater than that of the healthy bone ; it presents in its interior a regular compact mass like ivory, and is either smooth upon its surface-or has distinct studdings. To these must be certainly considered to belong those bonytumours whieh Astley Cooper has described as Cartilaginous Exostosis of the Medullary Membrane; Scarpa (a) as Exostosis maligna; Otto (b) and von Walther (c) as- Osteosteatoma; John Muller (d) has described it most minutely in all its relations- as Enchondron (Sarcoma cartilagineum, Tumor cartilaginous.), He speaks of a good kind of swell- ing of the bone, or even of the soft parts; for instance,.of the glands, which form a spheroidal tumour, not lobulated, and acquiring the size of a fist, or larger. When in the soft parts it has a thin covering- of ceHulartissue, but in bone, where it occurs most frequently, it appears like a soft ex-panskm of the bone overspread with perios- teum, the expansion being either developed fromv within, with a bladder-like expani sion of the thinned shell of the bone; or more rarely it appears to be produced from the exterior of the bone, and then is not necessarily enveloped in a bony shell. In the former case the bladder-like expansion of the. periosteum forms a sort of shell, enclosing the soft mass; sometimes there are merely single, isolated, insular, thin patches of bone. The joint-suriaces of the btone are generally in this disease either not at all or but little ehanged; even-whea>a phalanx-of the finger enlarges to a: tumour of the size of a. lemon and round, the joint-surfaces usually continue natural. The parts over the swelling in general remain unaltered^ although they be mucft expanded. Now and then the slow painless development of the tumour, as well as the constitution- continuing healthy for ten or twenty-years, lead to the notion that the swelling is not malignant. The contents of the tumour are soft, in. and upon the bone in general, with interwoven projections of spongy substance, which, how- ever, may be entirely deficient. The parenchyma, of the tumour usually presents, on being cut-into, two elementary parts, distinguishable with the naked eye, of fibro-membrannus, and a gray slightly transparent substance, similar to cartilage or lough jelly.- The fibro-membranous part, whieh is rarely, wanting, forms small or large cells, of the size of peas, or larger; and in the larger, smaller cells are often developed. In their cavities is a grayish, rather transparent substance, distinguished from cartilage by its softness, and rather resembling the soft hyaline, or glass-like cartilage, existing in some fishes, and sometimes-even like tough jelly. This sub- stance may be easily shelled out of the cavities, and can be readily broken up* When put in spirit of wine it still retains its slightly transparent character. The more transparent cartilaginous substance is massed together by partitions of mem? branous structure, and such conglomeration is peculiar to the enchondrorn, and does not occur in other swellings of bone. If the mass seem free on the surface little1 elevations are noticed, which-show-the conglomeration externally. Microscopic examination shows that the fibro-membranous part consists of transparent net-like fibres; the glassy mass completely resembles cartilage, and exhibits oval, round, semi-transparent cartilaginous corpuscles spread about in it. After boiling from ten to twelve hours, the enchondrorn of hone gives out a considerable quantity of gluten, which, on cooling, becomes well gelatinized, but in its chemical properties is en- tirely different from common gluten colla, but on the contrary, agrees with the pecu- liar gluten of cartilaginous fishes, the cartilage gluten, or chondrin, described by Muller. The chemical examination of the enchondrorn of.soft parts presents a dif- («r) De Expansione Ossium, &c.; in his tomie, Physiologie,. und Pathologie gehorig, De AnatomectPiithologiaOssiumCbmrnen- p. 22. Berlin, 1824. tarii. Ticini, 1827. 4to... (c) Journal fur Chirurgie und Augenheife (b) Neue Scltcne Beobaelitungen zur Ana- kunde, vol. xiii. part iii. . (d) Above cited, p. 31. 35* 410 exostosis; its causes, symptoms, ference, as on boiling the common chondrin, but then even no chondrin contains, on the contrary, a considerable quantity of jellying gluten. Usually the existence of enchondrorn proceeds from external causes, as bruises and the like, and this happens most commonly in childhood. I have, however, seen it in the metacarpal bone of the thumb of an aged man, in whom it first arose at a late period, and whose cure was permanent after its extirpation. A general cause of the disease is ordinarily not to be found, although tumours of this kind often occurring in different parts may lead to such conclusion, but the cure is usually permanent after amputation. I have noticed this also after the removal of an enchondrorn of the testicle, and in the upper third of the upper arm. The development of enchondrorn is in general without pain, and may so arise and continue increasing for a long while. If from any cause inflammation be set up in the swelling, it proceeds to suppuration, the swelling bursts, and the bone becomes necrotic. An interesting case of extirpation of the finger with its metacarpal bone, at the carpus, is given by Walther (a). Muller (b) has also collected the various ob- servations on enchondrorn, and it has also been written on by J. Herz (c). 2206. Exostoses may arise in all bones, but they most frequently appear ©n the compact parts of tubular bones, and on flat bones, in the middle of the thigh, of the shin bone, the upper-arm-bone, the radius and ulna, and on the bones of the skull, but rarely in the neighbourhood of the spongy joint-ends of bones. The proximate cause of exostosis is a change of the nutritive process of the bone from inflammation, in consequence of which a large quantity of phosphate of lime is. deposited in the bony tissue, and upon this its enlargement depends. The time required for its development seems correspondent with that for the natural formation of bone and callus, as its subtratum is at first soft, and only at a later pe- riod hardens. The occasional causes which bring about this inflamma- tion are, as already generally noticed, either external violence or internal disease, especially syphilis, gout, and scrofula. There may be so re- markable predisposition to exostosis, or an increasing deposit of bony sub- stance,.that very inconsiderable external violence may favour its forma- tion (d). Syphilis in general produces, especially as consequence of in- flammatory affection of the periosteum, superficial exostoses or nodes {Gum- mata, Modi, Tophi Venerei,) and most readily in bones little covered with soft parts. Scrofula more commonly gives rise to the exostoses which are seated deeply in the bony tissue. I have observed a similar predisposition to exostosis in. an otherwise healthy and Strong young man. 2207. The symptoms which accompany the origin and further develop- ment of exostoses vary according to their cause and nature. Sometimes they occur with more or less distinct symptoms of inflammation; some- times, however, without any pain. If the exostosis depend on syphilis, it is nearly always preceded by severe boring, or gnawing pain, setting in especially towards night, which at first spreads over the whole bone, but afterwards fixes on the point where the exostosis forms. In scrofulous exostosis the pain is duller and less severe: this is, however, in general the case, if the exostosis arise after external injury, when the pain usually soon subsides, and the swelling is so imperceptibly developed that it is commonly only first noticed when it has acquired some size. Exostosis principally forms either slowly or quickly; in the former, case the struc- (a) Ak>ve cited. (fc) Above cited; fci Dissert, de Enchondromate. Erlangen, 1843. dd), Abernethy, quoted in Samuel Cooper's Surgical Dictionary, p. 515. Edit, of 1"838. DIAGNOSIS, PROGNOSIS AND TREATMENT. 411 ture of the growth is usually very firm and the pain slight, in the latter the pain is very severe, the swelling grows quickly, and is often accom- panied with violent fever. Sometimes the pain, which had existed at first, subsides during the progress of the disease. Not unfrequently the swelling remains at a certain size, without further increasing, and without causing other symptoms than those produced by its seat and pressure upon the neighbouring parts, to wjt, a displacement of the muscles, disturbance or loss of motion of the part, wasting, paralysis, and the like: such is especially the case in firm idiopathic exostosis, which has been slowly developed. Less firm exostoses may run on to ulceration and ill-condi- tioned ulcers. A rare termination of exostosis, especially of the firm kind, is its complete separation by necrosis. 2208. The diagnosis of exostosis, in inference to its original causes, to the substance forming it, and the part of the bone where it has been originally developed, is founded on the following circumstances. Idiopa- thic is distinguished from syphilitic, and scrofulous exostosis by the pre- vious violence, and by the absence of the symptoms which syphilitic or scrofulous disease manifests. Syphilitic exostosis is always accompanied by the symptoms of general and inveterate syphilis, with nightly pains of the bones, is mostly situated in bones covered with little soft parts, and usually arises on the surface of the bone. Scrofulous exostosis is accom- panied with the general symptoms of scrofulous disease, and is mostly situated in the deeper bony tissue and the spongy joint-ends of bones. Slow development of the exostosis; leads to the expectation of a firm, ivory-like nature; whilst a quicker, progress, accompanied with much pain, points to a less firm structure. These symptoms are not, however, certain. When ulceration has taken place, it may be ascertained with the probe, or with the finger, from the condition of the parts. 2209. The prognosis of exostosis is in general unfavourable; it is most favourable, however, in the idiopathic kind, if it acquire a certain size, remain stationary, and is only inconvenient by its size and wTeight. Sy- philitic and scrofulous exostoses are always accompanied with a high de- gree of constitutional ailment; they may pass into malignant ulceration, which wastes the powers. 2210. The treatmeat is guided by the various causes and condition of the swelling. If syphilis or scrofula be at its root, the remedies opposed to these must be employed. If the pain be considerable, leeches, rub- bing with mercurial ointment and opuam, softening poultices with opium, and the like.. The dispersion of a true exostosis is never to be expected from the various dispersing remedies which have been recommended.for external use,ashemlock, mercurial, and ammoniacal plaster, Schmucker's plaster, rubbing in volatile salves, long-continued blistering; they may rather by their irritation, set up inflammation in the skin, increase the pain, and even encourage the enlargement of the swelling. In general the progress of the disease is not arrested either by general or local treat- ment. When these remedies have actually dispersed bony swellings, they were doubtless only inflammatory swellings of the periosteum. 2211. In idiopathic exostosis, the further increase of the swelling may, perhaps, at the onset, be prevented, by blood-letting, and the continued use of cold applications, and afterwards by dispersing remedies; its size may also, perhaps, be diminished. 412 OSTEOSTEATOMA AND OSTEOSARCOMA. 2212. If the exostosis be void of pain, if it do not enlarge, nor incon- venience the patient, or if situated on any part where mechanical treatment is improper, it is advisable to let it alone. But if the swelling be very inconvenient to the patient, and if its situation admit of me- chanical treatment, the only remedy is its removal. This requires the exposure of the swelling by a crucial cut, or by twro semilunar cuts at its base, and its separation with a fine saw, or with a chisel and hammer. If the exostosis be firm and large, it must be removed piecemeal; a horizontal cut with a saw being met by a vertical one. The treatment of the wound consists either in bringing together its edges, if the-part whence the swelling has been removed be sound, or in the application of a mild dressing, as has been described in wounds of bone with loss of substance. If the size of the swelling permit not its removal, amputation of the limb must be performed. In most cases the removal of exostosis is best effected by Hey's, Machell's (a), or Graefe's (b) saw, and Heine's bone-knife. When the position of the exostosis will not permit its removal in the above man- ner, instead of proceeding to amputation, its absorption should be encouraged by removing the periosteum from the swelling, in consequence of which its vessels are pulled out. This plan of treatment is at least recommended by Astley Cooper (c). On the side of the nail, especially, of the great toe, tumours not unfrequently arise which are hard and immoveable, covered with a glossy skin, their interior as hard as the bone from which they arise, and.they are mostly seated on a broad base. They cause considerable inconvenience in walking; after extirpation they soon recur, and the only remedy is the removal of the whole phalanx (d). 2213. Osteosteatoma and Osteosarcoma {Knochenspeck und Knochen- fleisch-Geschwulst, Germ.) and Spina ventosa (Winddorn,,Germ.) must be considered as allied:diseased conditions, inasmuch as in both there is an enlargement of the bone deviating from its natural condition, with which its nature is completely changed and converted, into a fungous, fleshy, jelly- cartilage- fibre- medulla- fat- or lard-like substance, in which are found larger or smaller, pieces of bone of various shape. 2214. The causes of osteosteatoma and osteosarcoma are partly external, partly internal; to the former belong violence of all kinds; to the latter, an ill condition of the juices, venerea], scrofulous, rheumatic, and gouty- diseases. Boyer and others suppose that osteosarcoma is of similar nature to carcinomatous degeneration' of soft parts, and support this opinion especially by cases; in which, after the removal of the disease, or after amputation of the limb affected with it, the same disease has taken place in other parts. According to my view such cases must be con- sidered as uxeduWavy fungus of bone. The formation of osteosteatoma and of osteosarcoma is always preceded by an inflammatory condition,,the cancellous membrane swells up and thickens, the cells of the bone expand, the membrane lining them pro- duces fungous growths, the nourishment of the bone is so changed, that there is no longer any deposit of phosphate of lime,, but a flesh- or lard- like, or other kind of substance, is produced. If such bone be subjected (a) Astley Cooper, above cited, pi. xv. figs. (d) R. Liston,. On the Cure of Exostosis 7, 8. of the last Phalanges of the Toes by excision (6) Schwalb, Dissert, de Serra orbiculari. of the Diseased Bone; in- Edinburgh Med. Berol., 1819. and Surg. Journal, vol. xxvi. p. 27. 1826. (c) Above cited. OSTEOSTEATOMA AND OSTEOSARCOMA. 413 to maceration, nothing remains but the partially-expanded cells of the bone, the walls of which are exceedingly fragile. The formation of osteosteatoma and osteosarcoma proceeds, although, most frequently, yet1 not alone, from the periosteum, as supposed by many, but also from the whole bone. Its firm connexion with the periosteum does not contradict this, as close connexion with the periosteum occurs in all irregular forma- tions of bone. 2215. The substance of which osteosteatoma and osteosarcoma consists, is various; sometimes homogeneous, lard-like, similar to a scirrhous gland ; the cells of the bone are much expanded, and filled with fungous growths, sometimes pap-like, gelatinous, and brain-like at certain parts; sometimes the tumour forms a hollow ball with firm walls, and its interior is filled with painless, sponge-like granulations. 2216. The Symptoms accompanying osteosarcoma or osteosteatoma, are not distinguished from those of exostosis. In most cases the disease is preceded by a deep-seated pain, which at first is slight and remitting, but subsequently fixed to the spot at which the swelling appears. As the substance grows, the pain in it usually becomes severe and lancinating; the skin is tense, sometimes inflames, at last bursts, hectic fever is set up, and the patient's powers are broken up. The ulceration may run into a canCer-like ulcer. Many differences, however, present themselves in the progress of osteosarcoma and osteosteatoma; the pain is sometimes very severe at the onset, and diminishes or entirely subsides afterwards; sometimes the disease remains in one definite state, and the pain ceases; sometimes the pain prevails with equal severity from the beginning to the end of the disease. It is self-evident that from the situation of the disease, from its spreading, and from the neighbourhood of important organs, symptoms may be produced. 2217. The external condition of the tumour varies; sometimes it is confined by well-marked bounds to one part of the bone, sometimes it involves the whole bone. In general, osteosteatoma and osteosarcoma have no precisely defined limits, but are gradually lost in the neighbour- ing parts ; the swelling does not entirely resist the pressure of the'finger, but shows rather some elasticity, and at several parts a seeming fluctua- tion, by which it is distinguished from exostosis. 2218. The treatment of osteosteatoma and osteosarcoma precisely agrees with that of exostosis. At first, if merely pain be present, remedies opposed to the cause of the disease must be employed, in connexion with blood-letting, cold applications and the like upon the affected part, for its somewhat possible prevention. These are the only remedies which can be employed for its control, when the swelling has already made some progress; howTever, usually, no advantage is thereby gained, and time is merely lost in the progressive increase of the swelling. The alone remedy, if the seat and condition of the disease permit, is the removal of the swelling with the saw, or with the chisel and hammer, or the amputation of the limb if tumour have attained considerable size, or the whole bone be affected. Where possible, the amputation should be performed above the next joint. The prognosis always remains in other respects doubtful, because in most cases the disease again shows itself on the scar, or on some other part. 414 SPINA VENTOSA, 2219. Spina ventosa or Pedarthrocace {Winddorn, Germ.) is a swelling partially or entirely occupying the whole extent of the bone, tolerably equal and regular, in which the nature of the bony tissue is in various ways conditioned. Sometimes a regular, firm bony crust, which is per- forated at different parts, forms the exterior of the swelling, in the cavities of which a cartilaginous mass is found with irregular, isolated or attached bony growths. Sometimes the external wall of this swelling is formed merely of very much expanded periosteum, and the substance within, as in the former case. Sometimes the interior contains one or several cavities, filled with variously coloured ichorous fluid, a reddish gelatinous substance, or with decomposed and clotted blood. In the walls of these cavities is found sometimes a cartilaginous, sometimes a lard-like substance, sometimes necrosed or carious pieces of bone, which must be considered partly as the remains of the destroyed original bone, and partly as a new production {a). 2220. This disease always declares itself a longer or shorter time before the swelling appears, by dull deep pain in the bone, which is set up either of its own accord, or after some external violence. The swelling appears either as a conical or spherical knob, or as a regular swelling, including the whole circumference of the bone. The pain is of varying severity, and often increases to a very considerable degree as the swelling in- creases. The soft parts surrounding the bone swell lip, the skin becomes painful, red, thins at the most elevated parts, bursts and discharges an ichorous fluid. The edges of the ulcerated aperture thin and drop in- wards, whilst the rest of the swelling retains. its. size and consistence. A probe passed through this opening can with ease be carried deeply in every direction, penetrating the cartilaginous substance, and but little arrested by the fragile pieces of bone. From the discharge of the juices, and the absorption of the ichorous fluid hectic symptoms arise at an earlier or later period; fungous excrescences spring out of the apertures, are exceedingly sensitive, bleed easily, and increase the exceedingly severe pain. [Our celebrated countrymen, Richard Wiseman, has given (b) a very excellent description of Spina ventosa, of which he says:—" It hath been taken notice of by very few authors, and I myself succeeded happily in the curing those in the lesser Bones, many years before I knew what name to call the Disease. And in truth I do not now greatly approve of the name, but shall acquiesce in it and represent it to you, as I have frequently seen it in my Practice in the King's-Evill, it being a certain species of that Disease, and of no other that I ever saw. It taketh it's beginning from a thin acid serum in the medullary juice, which corroding the Fibres maketh a solution of continuity there, and at length corrupteth the interior part of the Bone, and at last (if not prevented) corrodes the Shell, and passeth it's subtill Humour through some porosity it had made. This Disease of the interior part, by degrees usually so affecteth the exteraall Shell of the Bone, as to raise it to a preternatural] Tumour, which, at the same time, overstretching the Periosteum causeth an uneasiness; and this Pain if it grow so acute as to produce Inflammation, an Abscess consequently followeth. If the Bone be spungy and soft, it is wonderfull to see how quickly the Fibres of it will be mollified by the influence of the serum of the Blood, and made apt for a sudden Distention, as if the part were rather musculare than Bone. So in childrens Fingers, I have seen a Bone swelled in a night, and the like Tumour raised in the spongy Bones of elder persons in few days, without much difficulty to yield again to exsiccant Remedies. Yet it sometimes happeneth, that the interior (a) Delpech, Precis Etementaire, vol. iii. (b) Several Chirurgical Treatises. Lon. p. 583. don, 1676. fol. richard Wiseman's description of spina ventosa. 415 part of the Bone is totally corrupted without any externall Tumefaction or Pains, till the acid Humour maketh its way through the cortex, and eroding the Periosteum, causeth a solution of continuity there; which by access of pain swelleth and in- flameth the externall Parts, and produceth Maturation in few days. Those in the pro- tuberant Bones do also frequently raise Abscesses after the same manner, and some- times whilst the exteriour Parts suffer under another Ulcer different from this. Somewhat of their Differences I have showed you in the preceding lines, others may be taken from the Quality of the serum. In some there is a sudden Tumour raised in a night, in others it swelleth gradually, and never corrupteth externally. In others the Humour pierceth through the cortex, and Taiseth suddenly an Abscess. And these Differences may be said lo arise somewhat from the Place or Bone they affect: for, accordingly as the interiour part of it is softer or harder, or the externall cortex is solid orporous, so itsuffers Solution sooner or later. Those of the cranium for the most part pass their way through the interiour lamina and affect the dura mater, <$rc, producing great Pains, Convulsions, Spasmus, Epilepsies, and they die before the Disease is discovered. In the great Bones of the Knees, Ancles, Elbows, &c, they pass their Matter slowly, and are more generally diseased with Apostemations, ex- ternally arising from the protuberance of them. In the Os tali or Heelbone, which is spongy within, and full of externall pores, they make their way through more suddenly, and so accordingly they do in the Jaws, Fingers and Toes. The cause of the Spina ventosa I have already delivered you in short to be the Acid quality of the scrum sanguinis in the Bone. The most visible Signs of it are a protuberance of the Bones without discolouring of the Skin, and often Without Tumour or Pain. The Apostemations proceeding from the Spina ventosa do most certainly shew them, they rising always between the Membranes and Tendons, and somewhat of Fluctuation may be felt there before the external Skin be considerably inflamed : also if upon Opening it you make search with a Probe, you Will find it penetrate deep into the Bone, yet is the cortex of it white; whereas the other Abscesses do always begin externally, and if the Bone be bare, yet is it only superficially carious or stained by the Matter. The Cure of the Spina ventosa in the lesser Bones, as the Cranium, Jaws, Fingers, and Toes is feasable; but those in the bigger Bones are for the most part deplorable. Infants and Children are generally the subject of this Dis- ease." (pp. 262, 63.)] 2221. The ground of Spina ventosa lies in an inflammation and ulcera- tion of the medullary membrane of the bone, upon which depends the destruction of the bone from within outwards. The most common cause of thiscbmplaint is scrofula, although also syphilis, gout, rachitis, scurvy, smallpox, and the like, as well as external violence, particularly bruises, and concussions may give rise to it. The tubular bones, especially the metacarpal, metatarsal, and finger bortes, are most frequently attacked by this disease; but very rarely are the short and spongy bones, as the car- pal and tarsal affected with it. The degeneration of the spongy ends of bones, which has been considered with the different affections of the joints, (par. 221,) may indeed be placed, together With Spina ventosa, in the compact structure of tubular bones. In most cases, especially in the finger and metacarpal bones of scrofulous persons. Spina ventosa consists in tubercular formation in the bone^ and according to the degree of softening in the tubufcular mass, does the nature of the contents of the swelling vary. Hence the death of the bone is Caused to a definite extent, and on its throwing off does the cure first commence. In this disj ease, ordinarily, no new bone is produced, probably because the peri* osteum and the medullary membrane of the bone' are destroyed. Hence also the bone, after the cure of the disease, is Considerably shorter, and the corresponding finger drawn backwards. 2222. From the symptoms which accompariy the development atod further progress of Spina ventosa j the distinction between it and exostosis, 416 CAUSE AND TREATMENT OF SPINA VENTOSA. osteosteatoma or osteosarcoma, must, in many cases, he very difficult, Spina ventosa may indeed be distinguished from exostosis, inasmuch as it involves the whole circumference, whilst exostosis is more circum- scribed and confined to one definite part of the bone; the irregularities, however, which Spina ventosa at first exhibits, and the thickness of the soft parts covering it, render the certain knowledge of the difference be- tween them very difficult. In regard to the external form, Spina ventosa, for the most part, agrees with osteosteatoma and osteosarcoma ; its deve- lopment, however, is in most cases-more tedious than in both those dis- eases, and the pain is more severe and constant. 2223. Spina ventosa is a disease of importance, slow and difficult to cure, and proportionally more so when attacking adults. In general its treatment corresponds at the commencement of the disease with that already directed for exostosis, osteosteatoma, and osteosarcoma. Suitable remedies must be employed to counteract the internal causes, and the great hope in young persons, when the disease has originated in scrofula, rests on the use of antiscrofulous remedies; and by the often occur- ring total change of the constitution, at the period of puberty, the cure may be brought about, under which circumstances the necrosed pieces are thrown off" from the diseased bone, and fistulous openings close. Poultices of aromatic herbs, of decoction of savine, balhs of camomile, of hemlock, and the like, serve for local applications. If the tumour have burst, aromatic baths and poultices must be employed, and a free outflow given to the pus. For assuaging the very severe pain, frequent poulticing With hemlock, sometimes with the addition of opium, must be employed ; but if the disease have reached such degree that the powers of the patient are failing under hectic symptoms, amputation is the only hope. Laying bare, boring holes in the bony tumour, is also the appli- cation of acrid remedies, or even of the actual cautery, for the destruction of the diseased bone, are improper. The formation of tubercles in bone which has been referred to in various places, as in spondylarthrocace and Spina ventosa, and indeed pointed out by the older writers. (Galen, Severinus, Gerber, HancRe,) has been more carefully described by Del- pech and Neibert, but especially by the attention which the Anatomical Society of Paris have given to the subject (a), and by Nelaton's clever treatise (b) it has been carefully set forth. Of this treatise Pigne has given an abstract in his French Trans- lation of this work, which I the more readily here repeat, as it confirms many of my own earlier statements. The causes of tubercular formations in bone are those of tubercle in general. Most commonly it appears in childhood, although it is often enough noticed in adults. All the bones may be attacked with it, though the several bones may be arranged in the following way, according to the frequency of its occurrence in them; the vertebrae, the shin-thigh-and upper-arm-bones, (in children,) the fingers, meta- carpal and metatarsal bones, the breast-bone, ribs, iliac bones, the petrous portion of the temporal bone, and the short carpal and tarsal bones. The disease appears under two forms; the tubercular mass is collected in one or several cavities, in the middle of the bony substance (tubercula cystica, Lat.; tubercules enkystes, Fr.); it may be infiltrated into the cells of the bone (Infiltralio tuberculosa Lat.; infiltration tuberculeuse, Fr.) ^ A. The encysted tubercles appear during their progress in five stages (c):— (a) Bulletin de la Societe Anatomique de Paris. August and November, 1837; May and July, 1838. (6) Rechercbes sur 1'Affection Tubercu- leuse des Os. Paris, 1837. (c) I have translated this abstract from Pigne.—j. f. s. FORMATION OF TUBERCLE IN BONE. 417 1. Gray Granulations (Granulations grises.)—At the top of the affected part of the bone from which the periosteum has been removed, some vascular points are observed, forming violaceous marblings, and sometimes slight elevations which deprive the bone of its regularity. If layer after layer of the compact part of the bone be first removed, and afterwards its cellular tissue, a substance is reached of many lines in extent, formed by the union of little pearly granulations, half aline in diameter, of a white opaline colour. Many of these granulations, specially such as are at the periphery, are encircled by a little bony shell of very great tenuity and transparence. It is not uncommon to find some of these granulations, which present in their centre a yellow opaque spot, indicative of commencing transformation ; in the interstices separating them some exceedingly delicate vessels creep, which inosculate with those of the surrounding bony tissue, upon which a very distinct injection is perceived. The surface of the bone, at the nearest point of this tuber- culous deposit, is often doubled by a bony layer of recent formation. These granulations exhibit complete identity with those generally regarded as rudiments of pulmonary tubercles; they are pretty frequently met with on bones, which on other parts of their extent exhibit well-developed tubercles; and the lungs of per- sons in whom they are met with generally contain tubercles. The bony partitions which separate each of these granulations are not slow to be absorbed and disappear entirely, and then occurs the second period. 2. Crude encysted Tubercles (Tubercules crus enkystes.)—These granulations being united into one single mass, lose their primitive colour and appearance; the vessels and partitions which separated them have disappeared: there is soon merely an opaque-white mass, inclining to yellow, like that of putty, without any elasticity, and retaining the impress of the finger; it is homogenous, contains no bone, and presents sometimes slight marblings, more white, or slightly gray. This matter is contained in a cyst, which lines all the anfractuosities which the tubercular cavity presents. This cyst, which has but little thickness, is at first gelatinous, transparent, but ends in acquiring considerable resistance, and contains vessels more and more numerous as the tubercle increases in softness. The bony cavity is more or less regularly rounded, sometimes angular, and forming many adjacent cavities, which open into the central cavity. Its surface, though generally smoothed, presents sometimes a heap of little bony needles of exceeding delicacy, almost all parallel, and directed towards the centre of the cavity. At other times, instead of being entirely bony, these walls are formed of bony, fibrous and cartilaginous tissue; when, in consequence of its development, the tubercle has reached the surface of the bone, when it is immediately beneath the periosteum, the latter becomes hyper- trophied and adheres strongly to the cyst. For the rest, the bony tissue which bounds the excavation has preserved its natural density and texture; all the parts invaded by the tubercle, instead of being crowded together by it, are destroyed as it were by a punch. These tubercular collections have an extent varying from two to three lines in diameter, up to fifteen and twenty; they are generally not very numerous, and it is very common to find only one pretty large one, and many of small dimensions. When a tubercle is developed in a bone, its periosteum becomes more vascular, as also the bone at the point nearest the accidental pro- duction. This vascularity is soon followed by the deposition of layers of newly formed bone; besides, tubercles developed near the extremity of a bone, open more easily into the cavity of the joint than on the surface of the bone; and this may be imagined, inasmuch as having traversed the entire primitive bony tissue, the tubercle has still to traverse the bony layers of new formation, Whilst towards the joint no such analogous obstacle is met with. 3. Softened tubercles (Tubercules ramollis.)—The more slowly the matter contained in the cyst softens, and so soon as the softening operates regularly from the centre to the circumference, so soon does it proceed from one part of the periphery to pro- pagate itself to the whole mass. 4. Eliminary process (Travail d''elimination.)—The collection of tubercular matter proceeds then like a true abscess, which having reached the skin, inflames and perforates it, and gives vent to a grumous liquid, consisting of white, cheesy flakes, suspended in a turbid serosity. When all the matter is voided, a fistula remains, which daily furnishes a varying quantity of serous pus, 5. Reparatory process (Travail reparaieur.)—At the end of a period of very variable length, if the patient can stand against the abundant suppurations, a Vol. hi.—36 418 FORMATION OF TUBERCLE IN BONE. tendency to cure is manifested; the cyst acquires considerable increase, thickens, hypertrophies to the extent of entirely filling up the cavity which it lines, and ends in presenting completely the appearance of fibro-meduUary tissue. The termination of this affection is not always so fortunate; it may, however, be stated in a general way, that the disease tends much more towards a cure according as its primitive seat is nearer the skin. B. Tubercular Infiltration embraces three different states of the bone: 1. Gray infiltration (Infiltration grise.)—The bony parts which are affected present, in all the points which contain this tuberculous matter, spots of a grayish, opaline, slightly rosy tint, and semitransparent, formed by the deposit in the cells of the bony tissue, of a substance analogous in appearance to encephaloid substance; the circumference, instead of being lost insensibly, is suddenly bounded by a change of colour. By the aid of a lens these spots are seen traversed with blood-vessels of very great delicacy, and sometimes by a very well-marked circle of injection. The density of the bony tissue is neither increased nor diminished. 2. Purulent infiltration (Infiltration purulente.)—The infiltrated matter assumes, after a longer or shorter time, a pale yellow tint, and becomes completely opaque; it is at first pretty firm, but is not delayed in gradually softening; soon is it entirely fluid and puriform ; these collections are always very precisely bounded, as are the spots already mentioned. When the infiltration has reached this period the blood- vessels disappear; the bony tissue undergoes an interstitial hypertrophy, without the bulk of the bone being increased; the little cells are narrowed, and almost com- pletely obliterated, and the cellular tissue of the bone is then as it were like ivory. 3. Sequestration of ihe affected part (Sequestration de la partie affectee.)—When the bone has undergone the modifications just mentioned, it exhibits all the characters of a true sequester; there is neither vessel nor any indication of remaining life; besides, a circle of elimination is formed around the infiltrated portions, and the sequestration runs through the whole series of phenomena characterizing necrosis; abscesses, fistulas, abundant suppuration, and so on, are the inevitable result. In some instances necrosis evidently exists, but its separation is long delayed. It some- times happens that the necrosed part is detached by little fragments, and in the cyst which forms around the abscess a quantity more or less considerable of bone, like sand, is observed. On the other hand, this purulent infiltration is often propa- gated to neighbouring parts, and attacks a large extent of bony tissue; these cysts are rarely so limited as in encysted tubercle, and it is notvery uncommon to see a consecutive and accidental caries developed not in the part primarily infiltrated, but in the bony tissue which surrounds it. Purulent tubercular infiltration has been often confounded with caries; but it is easy to perceive that these two affections differ essentially from each other; in fact, caries always proceeds from the periphery to the centre, and infiltration on the con- trary, from the centre to the periphery. In infiltration,* there is an interstitial hypertrophy, augmentation of density, absence of vascularity ; in caries, there is a rarefaction, softening and increased vascularity of the bony tissue. Finally, the interstitial hypertrophy is sufficient to distinguish this affection, and that of necrosis, and of inflammation with suppuration of the medullary membrane of the bone. As to the treatment little remains to be said. The tuberculous affection is beyond all the resources of art; when it affects an important organ, the patient is generally devoted to death; when it affeets the bony tissue, it is rare that it has not been de- veloped in the lungs or in some other organ. However, when it only affects the bones, it may be hoped, that nature will effect the cure; especially if her efforts be seconded by a wholesome diet,a residence exposed to the sun; in a word, by atten- tion to the treatment of scrofula. This happy result is much more frequent at the period of puberty than at any other time of life." (p. 491-93.) [A translation of Nelaton's excellent paper by Dr. King will be found in the N. Y. Journ. of Med. & Surg., vol. i. 1839.—g. w. n.] FUNGUS OF DURA MATER, AND OF SKULL-BONES. 419 VIII—OF FUNGUS OF THE DURA MATER, AND OF THE SKULL-BONES. {Fungus Burat Matris, Lat,; Schwammige Auswuchs auf der harten Himhaut, Germ.; Fongus de la Dure-Mere, Fr.) Kautfmann, Dissert, de Tumore capitis fungoso post cariem cranii exorto. Helmst.; in Haller, Disput. Chirurg. Select., vol. i. p. 49. Locis, Memoires sur les Tumeurs fongueuses de la Dure-Mere; in Memoires de PAcad. de Chirurgie, vol. v. p. 1. Sandifort, Exereitationes Anatomicae, cap. iii. Lugd. Batav., 1785. ■----, Museum Anatomicum Acad. Lugd. Batav., p. 142. L. B., 1793. vox Siebold, C; in Arnemann's Magazin fur die Wundarzneiwissenschaft, vol. i. part. iv. p. 142. Wenzel, J. and C, Ueber die schwammigen Auswuchse auf der aussere Him- haut. Mainz, 1811. fol.; with six copper plates. von Walther, P., Ueber die schwammigen Auswuchse auf der harten Himhaut, nach eigenen Beobachtungen; in his Journal, fur Chirurgie und Augenheilkunde, vol. i. p. 55. Schwarzschild, H., Dissert, de Fungis Capitis. Heidelb., 1825. 4to.; with four lithographed plates. Seerig, A. G. H., Nonnulla de Fungi Durae Matris origine et diagnosi. Uratis- laviae, 4to.; with three lithographed plates. Ebermaier, Ueber den Schwamm der Schadelknochen und die schwammartigen Auswuchse der harten Himhaut. Diisseldorf, 1829. 4to. Chelius, Zur Lehre von den schwammigen Auswiichsen der harten Himhaut und der Schadelknochen. Heidelb., 1831. fol.; with eleven plates. Unger, Beitrage zur Klinik der Chirurgie, vol. i. p. 264. Kosch, Beitrag zur der Lehre von den Schwammgewachsen am Kopfe; in von Graefe und von Walther's Journal, vol. xxiv. p. 542. Osius; in Heidelb. Med. Annalen, vol. iv. part iii. 2224. Fungus of the dura mater is an unnatural growth, arising from the surface of that membrane, which in its further development, by the destruction of the bone, thrusts up beneath the external coverings and raises them into a tumour. , 2225. The symptoms at first occurring in this disease, are extremely uncertain and indefinite, as headach, sometimes slight, at other times very severe, often periodical, sometimes spreading over the whole head, and sometimes fixed to one spot; afterwards dizziness, a sensation of concussion and confusion in the head; vomiting, pallid countenance, and wasting; loss of sensation in some one part and the like. Sometimes, however, in the early stage, the disease presents no symptoms. As the fungus enlarges upon the surface of the dura mater, that membrane is separated to a greater extent from the skull, and partly in consequence of this, and in part by the pressure of the swelling, the bone is destroyed by absorption. Before the tumour bursts through the outer table of the skull, that part of the bone crackles under pressure of the finger. 2226. When the bone is destroyed and the fungus has arrived under the coverings, of the skull, it presents a regular, circumscribed more or less elastic soft swelling, over which the colour of the skin is unchanged. This swelling in general enlarges but slowly, and presents as characteristic signs; first, the sensation of pulsation, as observed, though more actively, in aneurysm; second, the edge of the hole in the bone, through which the tumour protrudes, is distinguishable around the whole circumference of the swelling, more or less rounded or sharp, and having numerous pointed 420 PROGNOSIS AND DIAGNOSIS projections; third, on the condition of this bony edge depends the greater or less painfulness of the swelling; fourth, the possibility of returning the swelling into the cavity of the skull with sudden cessation of its painful- ness, under which circumstance, the fungus is no longer exposed to the influence of the edge of the hole in the bone. With the external pro- trusion of the tumour, is often connected danger of very urgent symp- toms, as small pulse, vomiting, continual gulpings, cold hands and feet, frequent faintings, and cold sweats over the whole body. These symp- toms, together with loss of sensation, palsy, and loss of intellect, may be consequence of keeping back the fungus by art, or by change of position to the other side. 2227. The pulsation often diminishes as the swelling increases, and is scarcely perceptible; the edge of the hole in the bone may also be con- cealed as the outer part of the swelling spreads over it. The skin becoming still more tense, reddens, thins, at last bursts, and a fungus protrudes through the opening, which bleeds frequently, and secretes an ichorous fluid mixed with blood. Hectic fever arises in consequence of this loss of the juices, of the restlessness, and of the violence of the pain; and under the colliquative symptoms death ensues, preceded for a longer or shorter time by a sleepy state, frequent faintings, loss of some of the senses or of the powers of the mind. 2228. Examination after death exhibits a swelling of a brownish colour, sometimes more or less grayish white, at some parts often a medullary substance, of which some lobes are enveloped in their cellular tissue, and to a certain extent held together. This substance is penetrated by more or less vessels, in general connected not very firmly with the dura mater, and not at all organically with the edge of the hole in the bone, but only retained by the pointed projections and dentations of the edge of the bone. Upon the external surface of the bone, the edge of the hole is sharply defined, but on the inner table it runs off obliquely, so that the inner plate is always further destroyed than the external; a decided proof that the fungus has burst through the skull from within outwards. This is also shown by preparations, in which the fungus not having yet com- pletely destroyed the bone, the external table is undisturbed, and neither the bone nor the pericranium in any way diseased. Not unfrequently such swellings appear on several parts of the skull in various degrees of development, just like swellings situated on other bones of the body. 2229. Fungus of the dura mater is distinguished by the above de- scribed symptoms from other diseases of the skull, from encysted, meli- cerous, and atheromatous swellings, and from hernia cerebri, and specially as the latter either exists from birth or is produced after some injury of the skull, accompanied with loss of substance. Schnieber {a) has indeed mentioned a congenital fungus of the dura mater; I have, however, with Seerig (6), doubts of the correctness of the diagnosis in this case. 2230. The views already stated in reference to the origin and course of fungus of the dura mater, which have been specially laid down by Louis, Wenzel, and others, and which I have found confirmed by my own observation on the living and by examination of the dead, are op- posed to those advanced by Sandifort, Siebold, and Walther. Ac- (a) von Graefe und von Walther's Journal, vol. ii, p. 64.1* (6) Above cited,. p.,24. OF FUNGUS OF THE DURA MATER. 421 cording to the latter writers, fungus of the dura mater is a simultaneous degeneration of the dura mater, of the skull-bones, and of the external periosteum, but especially of the blood-vessels which pass from the latter to the diploe, and from it to the dura mater; a luxuriant vegetation of the net-like tissue between the two tables of the skull-bones, with which the bone-earth is sucked up and a carnation of the bone at the same time arises. This opinion, which had already been advanced by Louis in some cases, Wenzel (a) admits only so far as he supposes that the original seat of the disease is restricted merely to that part of the bone on which the diseased cause so operates, that the natural functions are in some way disturbed and interrupted; and this may be sometimes the outer, sometimes the inner table of the bone, sometimes both together, and sometimes the fungous tissue which lies between them. 2231. Directly opposed to the symptoms on which Wenzel founded his diagnosis of this disease, are those which Walther has advanced, supported by his own views and careful observation. He did not, indeed, notice any motion of the swelling ; the patient experienced only a certain roaring and rushing, best comparable with that which sometimes is per- ceived in the external ear-passages in violent beating of the carotid artery and its branches. A certain obscure movement was felt in the swelling, but however only when the hand, or still better the tips of the fingers, are applied and pressed strongly upon it for a long while; the movements are in this way, after some time, distinctly felt. In one case an alternate rising and sinking of the tumour was observed, similar to that concussion which the beating of the arteries produces in all parts of the body. Its degree corresponds with the number and extension of the arteries in the swelling; the movements are similar to the beats of the pulse, and cor- respond with them. Walther could not feel any bony edge around the circumference of the swelling, and considered this proved, because the hole in the bone was firmly, and throughout its whole extent filled with the swelling. When ihe fungus attains considerable size, no symptoms of compression of the brain are observed ; but in very rapid growth they possibly may be. The external part of the tumour can be returned. through the hole in the bone never, or but very rarely, and only whilst it is still small and recent, in which case symptoms of compression of the brain must at once ensue. Walther found, in general, that the swelling was completely free from pain, and that it was in no way sensible of touching, or of moderate pressure. The connexion of the fungus with the skull-bones was always firm. The periosteum began to thicken at a considerable distance from the swelling; and the thickening increased as it approached the tumour, and there the periosteum seemed reddened; it was firmly connected, with the fungus. 2232. Both these opinions are true, and founded upon careful observa- tion ; but it is improper to attempt setting aside the one by the other, as both are obtained from different states of the disease. The opinion of Louis and Wenzel is applicable only to the true fungus of the dura mater; that which Siebold, Sandifort, Walther and others have noticed, is not entitled to the name offungus of the dura mater, but is to be distinguished as a fungus of the skull, {Fungus cranii,) as the degene- (a) Above cited, p. 95. 36* 422 KINDS AND CAUSES OF ration in it begins either from the diploe, or from the dicra mater and pericranium at the same time, and the bone is converted into a fungous substance of greater or less firmness. This distinction between fungus dure matris and fungus cranii equally applies to similar degenerations in other bones, where fungus growths are developed between the periosteum and bone, and the bone is destroyed merely by these increasing masses; whilst other fungous groioths proceed from the bone itself and from the medullary substance, and the bone is converted into a fungous, sarcomatous, steatomatous, or other kind of substance. Those growths which are formed on the external surface of the dura mater in con- sequence of ulceration of the skull-bones, must be distinguished from true fungus of the dura mater. 2233. If the several origins of fungus be reviewed, five different forms, must, according to the observations of myself and others, be distinguished. First. The dura mater alone is capable of fungous degeneration, which appears either on its internal or external surface^ or on both at once. The fungous parts of the external surface of the dura mater are connected firmly with the more or less completely destroyed internal surface of the skull, so that the organically connected excrescence of the dura mater is converted gradually into the same fungous, steatomatous, or fibrous substance. When this degeneration gradually affects the skull-bones throughout their whole thickness, and by its external protrusion forms a swelling, it becomes firmly connected with the bone, and imperceptibly involves it, so that perhaps only at certain parts can its bounds be per- ceived through the firm edge of bone. Such tumour admits of no return, nor is any pulsation felt; at least the pulsations of the brain can alone be communicated to it when a large extent of the skull is included; they can, however, only be very slight, and distinguished always by their regularity, from the pulsation of single vessels, with their numerous ramifications in the swelling. In the other kind of isolated fungous degeneration of the dura mater, the degeneration is restricted entirely to it, and ordinarily to to its external surface alone. The fungus arising from the external surface of the dura mater is especially characterized by the enlargement of its substance, without destroying the surrounding parts otherwise than by pressure, on which account the fungus is only organically connected with the seat of its original development, and never with the bones of the skull, which it destroys. The destruction of the bones, already noticed as occurring in the progressive increase of the fungus, always corresponds to the extent of the tumour, extends from within outwards, and at last bursts through the external table of the skull, so that the swelling is perceived externally beneath the coverings of the skull. Hence on examination, according to the various degrees of development of the fungus, more or less deep hol- lows are noticed on the inner table of the skull; and when the skull is completely burst through, the destruction of its inner table is always to a far greater extent than the opening in the outer table, its edge sharply defined, and without exhibiting any other change. When the swelling appears externally, the edge of the bone throughout its whole circum- ference is distinctly perceptible ; the swelling pulsates actively and syn- chronously with the beat of the arteries, and so long as it has not acquired FUNGUS OF THE DURA MATER. 423 considerable size, may be wholly or in part returned into the cavity of the skull, and then more or less severe symptoms of compression of the brain occur. The pericranium surrounding this swelling is either sac- like or more or less united to it, which merely results from the continued pressure and inflammatory irritation, as noticed in all tumours in relation to their coverings and envelopes. 2234. Second. The dura mater and pericranium may degenerate at the same time, so that if a fungous mass is formed between the two and the corresponding surfaces of the skull-bones, with which it is organically connected, the destruction of the bone results only from its conversion into this substance, and proceeds from its two surfaces towards the middle, so that the diploe is at last destroyed. So long as the fungous mass has not completely destroyed the bone, it forms a more or less large and elevated swelling, which is either imperceptibly lost in the bone, or an edge of bone can be felt here and there on its circumference. The swelling is more or less firm, shows no trace of communicated pulsation from the brain, so long as the skull still remains not completely destroyed; and only when there is great vascular development in it, can the isolated pulsation of the several vessels be distinguished by examination with the fingers, but which, in reference to its strength, cannot be compared with that in true fungus of the dura mater. 2235. Third. The fungous mass may be developed between the skull and the pericranium, as fungus pericranii. Here, at least according to the observations hitherto made, the substance is always firmly con- nected with the bone ; indeed, for the most part, is formed by the diseased change of the bone. The substance may form considerable growths, and may also spread more towards the surface. When the fungous mass has changed the skull through its entire thickness, it is always so closely and firmly connected at its edge with the bone, that those symptoms which exist in true fungus of the dura mater cannot be present, and the swelling is specially under the same circumstances, as a swelling of like kind on other bones. 2236. Fourth. The degeneration begins in the net-like tissue of the diploe, and extends gradually inwards and outwards, or more towards the one than the other. The swelling is here equally firmly and organically connected with the bone; when it has completely destroyed the bone at the seat of the degeneration, it presents a similar connexion with the dura mater and pericranium; and there is neither pulsation nor possi- bility of replacement; at the very most the edge of the bone can only be perceived at one or other place. 2237. Fifth. There may be, finally, several of the above-mentioned diseased, and in regard to their origin, different changes present at the same time, according to which the symptoms variously present them- selves (a). 2238. The causes of fungous growths of the dura mater and skull- bones are either internal or external. To the former belong syphilis, rheumatic affections, scrofula, and other diseases which are connected with an altered condition of the juices. To the external causes belong blows upon the head, bruises, concussion of the skull without external (a) Chelius, above cited, p. 69. 424 OPERATION FOR FUNGUS OF THE DURA MATER. injury or fracture of the bone. The distinction of the causes is frequently attended with great difficulty, as the external injury has often so long preceded the origin of the complaint, that its causal relation to it is doubtful. When the disease arises without external violence, the presence of internal disease is not always clear; but the progress of the complaint, and the existence of similar degeneration in other parts, points to a peculiar diathesis, often characterized by no other symptoms than the tumour: and in this respect, indeed, it must be distinguished as the diathesis fungosa. I do not imagine, that without this internal condition, external causes can of themselves produce such fungous degenerations. As the result of these causes, an inflammatory condition is always to be considered as the peculiar commencement of the disease, by which plastic exudation, irregular vascular development, and the like, are produced. According as these processes occur, at the same time, on the surface of the dura mater, in the bone itself, under the pericranium and upon the dura mater, the proper fungus dure matris and fungus cranii are produced. 2239. Fungus of the dura mater, and of the skull-bones, is a very im- portant disease, which left to itself causes death, and the cure of which, or even its mitigation, is usually impossible. In those cases where the complaint is, from the symptoms mentioned, {par. 2225,) supposed to have arisen from external injury, its development may perhaps be arrested by the early and continual use of cold applications, by taking away blood, active purging, low diet, and the like. But if the swelling have already become apparent externally, there is no remedy but its removal, by the ligature or the knife after previously laying bare, and enlarging the hole in the bone; cutting into the tumour, the constant application of pressure, and the use of escharotics, can only promote an unfavourable result. Walther supposes that the operation is contraindicated in fungus of the dura mater, and that only the peculiar kind and special condition of the case, may here and there form an exception. He is confirmed in this opinion by the view he takes of the origin of the fungus, and by an operation he performed, in which, after the first cut, so severe bleeding ensued, that he was obliged to abstain from finishing the operation. In reference to fungus cranii, I must, from my own observation, assent to this opinion. But the operation for true fungus of the dura mater must be considered permissible, if the disease have not advanced too far; if there be only a swelling, and no degeneration of the other parts. The prognosis, however, in this operation, is always extremely doubtful; independent of its danger, it has scarcely ever a permanent result, as, at least according to my experience, the fungus of the dura mater is always characterized as medullary fungus (Fungus medullaris,) which, on account of the general diathesis is always incurable. 2240. In performing this operation, the general coverings are to be divided upon the swelling with a crucial cut, extending beyond it on either side to the extent of an inch ; the flaps are then separated and turned back. The galea aponeurotica and periosteum are found uncon- nected with the tumour, and to be divided like the skin, for the purpose of laying bare the fungus; or this may be done by two cuts on the base of the swelling. The edge of the hole in the bone having been exposed, it must be endeavoured by repeated applications of the crown of the trephine, and by removing the intermediate pieces with Hey's saw, to obtain a space large enough for the examination of the base of the OPERATION FOR FUNGUS OF THE DURA MATER. 425 swelling. If its connexion with the dura mater be then found not very firm, it may be separated with the finger, or with the knife-handle; or if its connexion be firmer, it may be carefully cut away with the knife ; of that part of the dura mater to which it is attached may be cut off; or a ligature may be applied with a loop-tier, which, however, on account of the readiness with which serious symptoms are set up, should be tied with very great caution (a). The after-treatment is to be guided according to the rules laid down for the operation of trepanning. Only under the above-mentioned restrictions, is the removal of the fungus permis- sible ; in every other case the operation merely hastens death. Thus, in Berard's (b) case, who by means of sixteen applications of the trephine, made an opening in the skull five inches long and four and a half wide, which laid bare the dura mater with the longitudinal sinus and the upper edge of the falx, after the removal of the outer part of the swelling, pulsation was observed in the rest of it; fainting and convul- sions immediately ensued, and the patient died in twenty-four hours. The swelling arose from the outer surface of the dura mater, and after destroying the bone, had protruded through an oblong aperture, whilst its base spread beneath the skull. Its structure resembled that of brain. The inner surface of the dura mater was healthy. Orioli (c) removed a fungus of the dura mater successfully. A little swelling projected beneath the right ear, accompanied with loss of sight, and had gradually reached the size of a small nut. The whole swelling pulsated, but was compres- sible, and the pulsation then ceased ; it also for the most part ceased when the tem- poral artery of that side was compressed. Neither bony edge nor crepitation was felt beneath, or on the side of the swelling. The disease was thought to be a tem- poral aneurysm. In three weeks the tumour had increased about two-thirds; head- ach and singing in the ears came on, and an operation was thought necessary. The artery having been compressed, a T shaped cut was made through the coverings, and the temporal muscle cut through; but the tumour was deeper, and the operator ascertained it was not aneurysmal, and that the bone was probably affected. After dividing the pericranium, a hard, irregular edge was felt around the swelling. The pericranium having been separated, the bone was found carious to the extent of a half-dollar; the tumour was seated with a broad base upon the dura mater, and diffi- cult as it was, Orioli removed as much as possible of the length and breadth of the fibro-fleshy mass. Two arteries were plugged, and the patient dressed. On the ninth day the wound was sloughy; the slough separated gradually, and some pieces of brain were also thrown off. The bottom of the wound now pulsated synchro- nously with the arteries and with the movements of the brain. As the wound cleansed, there appeared however on one side a swelling, similar to the former, which was successfully compressed with lint. In fifty days the cure was complete. A firm scar covered the part where the whole in the bone was, and the movements of the brain were felt. The singing in the ears subsided ; sleep returned, but sight was completely lost. Besides the above-mentioned writers, the following may also be consulted :— von Siebold, B., Entstehung und Ausgang einer betrachtlichen und mit dem Winddome am Schadel verbundenen scrophulosen Speckgeschwulst auf dem Scheitel; in Chiron., vol. ii. p. 667, pi. 8, 9. Palletta, De Tuberculis ossivoris. De Tuberculis Capitis, p. 93; in Exercita- tiones Pathologicae. Mediol., 1820. Eck, Kleiner Beitrag zu der Lehre von den schwammigen Auswiichsen an dem Schadel; in von Graefe und von Walther's Journal, vol. v. p. 105. Graff, K., Die Metamorphose der Schadelknochen in Markschwamme; in von Graefe und von Walther's Journal, vol. x. p. 76. Cruvelhier, Anatomie pathologique du Corps humain, livr. viii. Muller, B., Dissert, de Fungo Durae Matris et Cranii. Monachii, 1829. Blasius, De Fungi Durae Matris accuratiori distinctione. Hal., 1829. fa) Ficker, Ueber die schwammigen Auswuchse aufder harten Himhaut; in von Graefe und von Walther's Journal, vol. ii. p. 218. (6) Gazette Medicale, vol. i. p. 735. 1833. (c) Bulletino delle Soienza Mediche. May, 1834. 426 OF FATTY OR ADIPOSE TUMOURS. Hubner, Dissert, de Fungo Durae Matris. Heidelb., 1832. Seifert, Dissert, de Fungo Capitis in universum, et de Fungo Durae Matris in specie. 1833. IX.—OF FATTY OR ADIPOSE TUMOURS. (Lipoma, Tumour odiposus, Lat.; Fellgesehwulst, Germ.; Lipome, Fr.) Schreger, Ueber Lipome und Exstirpation derselben; in his Chirurgische Ver- suche, vol. i. p. 297. von Walther, P., Ueber die angebomen Fetthautgeschwiilste und andere Bild- ungsfehler. Landshut, 1814 ; with two plates. von Klein, Ueber die Ausrotung verschiedener Geschwulste; in von Graefe und von Walther's Journal fur Chirurgie und Augenheilkunde, vol. i. p. 109. Brodie, Sir B. C, Lectures illustrative of various subjects in Pathology and Sur- gery. London, 1846. 8vo. 2241. The fatty, or adipose tumour, depends on an unnatural collec- tion of fat, heaped up either in the panniculus adiposus, or between the plates of the cellular tissue beneath the skin, according to Schreger, in the mucous bags of the first and second orders. 2242. These tumours are developed slowly, and without any uneasi- ness ; they give to the touch a peculiar softness, which cannot be better compared than to that of a bag filled with cotton ; their surface is irre- gular, and distinct conglomerations are felt upon them, which are not hard, and are easily compressed. When they have reached a certain size, they in general grow quickly, and may acquire a very considerable bulk. As long as the swelling is small, the skin upon it remains unchanged, but when it has become very large, the circulation is impeded by the drag- ging and tension of the skin, the cutaneous veins become expanded, drop- sical swelling takes place, the skin inflames, especially if the tumour be seated on any part where it can be affected by chafing or external injury, and the inflammation may run on to ulceration. The form of a fatty tumour is in general oblong, and has a neck. [That fatty tumours have generally a neck is not, according to my observation, correct. They usually have a broad base, and raise up the skin like hillocks. Very rarely they have a neck; and in St. Thomas's Museum is the cast of a very remarka- ble one, which weighed from fifty to sixty pounds, was attached by a narrow pedicle to the throat, and hung down to the man's knees. John Hunter saw him, when the tumour was only of small size, and did not think it could be safely removed. The man died some years after in Shoreditch Workhouse.—j. f. s.] 2243. According to the two-fold origin of fatty tumours already men- tioned, {par. 2241,) two different kinds may be distinguished which are characterized by marked symptoms. Those fatty tumours which belong merely to the panniculus adiposus, and are only knobby masses of fat at certain parts, have no well-defined edges, but subside into the surrounding parts, {Lipoma diffusum,) are very soft and easily compressible, and so connected with the skin that the latter can be moved or lifted in folds upon the swelling. The fat lies under the generally thinned corium; no general sac exists, and some parts only are enclosed in thin and simple walls. The fat is similar to that of other parts of the body, only a little firmer. [This is the form of fatty tumour which Brodie mentions as "not well defined; in fact there is no distinct boundary to it, and you cannot say where the natural adipose structure ends and the morbid growth begins." He relates the case of a KINDS OF FATTY OR ADIPOSE TUMOURS. 427 person with an affection of this kind, "an enormous double chin hanging nearly down to the sternum, and an immense swelling also on the back of his neck formed by two large masses, one behind each ear, as large as an orange, and connected by a smaller mass between them. * * * Such deposits may probably take place in any part of the body, but I have seen them," says Brodie, "more frequently in the neck than elsewhere." (p. 275-77.) Not unfrequently very stout persons, more especially women who have borne children, have large collections of fat between the skin and abdominal muscles below the navel, which hang down in a thick fold, like an apron, to the pubes. It has been dignified with the name of pendulous belly. The female breast also sometimes becomes enormously loaded with fat, even in very young women. Brodie mentions a case of this kind, which grew so large that it was removed on account of its inconvenient size, which on dissection turned out to be "a fatty tumour, and a chronic mammary tumour, blended with each other," and disposed layer on layer, (p. 281.) But whether on the neck, belly, or else- where, it seems to be merely a superabundant deposit of fat, a hypertrophy, whieh can hardly be considered a disease, though it certainly is a great inconvenience.— j. f. s.] 2244. The other fatty tumours which arise between the two plates of the cellular expansion beneath the skin, from an increased and altered vegetation of the raucous bags of the first and second order, are situated deeper, are covered with the panniculus adiposus, have a defined boundary, greater mobility, more elastic hardness, and are enveloped in a proper cellular cyst, which is commonly so firmly connected with the fat that they can scarcely be distinguished. In general this cyst is very thin, often still thinner as the swelling becomes larger; only in rare cases is it firm, tendinous, and in part cartilaginous. This tumour consists of spherical masses of fat, which differ from the natural fat, nearly re- sembling a slice through the brain, or through a lymphatic gland, without cavities and partitions; sometimes they appear as if composed of circularly twisted or radiately disposed plates {a). With the opinion of this two-fold form of lipoma, which may be sufficiently distinguished by external examination, microscopic observations also agree. The substratum of lipoma is the fatty tissue intermingled with blood-vessels and cellular tissue in indefinite proportions. The lipoma which belongs to the panniculus adiposus, consists of cellular tissue, with a few vessels, and sometimes starlike groups of needle-shaped crystals, (margarin, or margaric acid,) are found in the fat- cells. In the other form more bundles of cellular fibres are observed, which spread between the groups of fat-cells. J. Muller (b) divides fatty tumours into, first, Lipoma, in which the fat is found in the common fatty cellular tissue, and is merely isolated by the walls of numerous cells thrust together; second, Fatty cysts, in'which the fat is not contained in little cells, but partly fluid, partly in form of fat-corpuscles, is enclosed in one large and generally thick membranous cyst. In the former case, the production of the fat goes on in the ordinary way, as previously in the healthy body; in the latter there-is, as it were, one predominant fat-cell, and its wall thickens into a firm cyst. The lipoma, generally lobed, is not distinguished from the ordinary form of fatty cellular tissue, its cells are roundish and oval, the single difference consists in the firmness of this conglomeration of fat-cells, which usually possesses a more or less strong cyst of thickened cellular tissue, whilst the single lobes are enclosed in thinner layers of cellular tissue. Muller distinguishes, a. Lipoma simplex; b. Lipoma mixtum^ where the insterstitial cellular tissue considerably thickened and membranous, forms strong plates, which run through the lipoma, rendering it firmer than the common lipoma; c. Lipoma arborescens, branching productions, which consist entirely of fatty cellular tissue. The fat cyst (Cystis adiposus) is, at least in the skin, similar to the Tumor sebaceus. The fatty tumour in layers (Cholesteatoma) consists of pearly shining leaves or layers of polyhedric cells, without any lobular (a) Schreger, De Bursis Mucosis subcutaneis, p. 12. Erlang., 1825. (b) Above cited, p. 49. 428 FATTY OR ADIPOSE TUMOURS; formation. The tumour, of the consistence of suet, is surrounded by a membrane generally very thin, rarely thicker than a common cyst. The cholesteatoma also occurs as a deposit upon ulcers. It has not any blood-vessels (a). [Fatty tumours of this kind vary considerably in size between half a pound and half a dozen pounds; but some examples have occurred of enormous bulk. Astley Cooper removed a fatty swelling of the breast which weighed fourteen pounds and ten ounces; it is in the Museum at St. Thomas's. Copland removed one from a female's thigh, weighing twenty-two pounds. The largest which has been met with in this county, is that removed by Astley Cooper (b) from a Danish sailor in Guy's Hospital, which covered all the front of the belly below the navel, and formed an immense swelling, which after removal weighed thirty-seven pounds and ten ounces. It was a remarkable circumstance in this man's case, that notwith- standing this bulky protuberance, he had done his duty on shipboard till within a few days of his admission. The tumour is in the Museum at St. Thomas's. Lawrence (c) mentions that a French surgeon removed a fatty tumour from the left hypochondrion, which weighed forty-six pounds, and was one of eight in the same person, the others of which, however, were not so large. Portalupi (d), of Venice, removed a large pyriform fatty swelling which hung from the left side of the neck and chest, measured in length twenty inches and a half, twenty-seven inches around its upper narrower part, and thirty inches below, and weighed fifty- two pounds; no blood-vessel of size was divided, nor was any ligature required; and in the course of seven weeks, the patient was cured. Although generally seated almost immediately beneath the skin, these fatty tumours are sometimes situated beneath the muscles, and then give rise to much difficulty in diagnosis, of which Brodie mentions a good example, where the tumour Was beneath the trapezius ; in another case the fatty mass was behind the gland of the breast, which it had lifted up, and caused great doubt as to the character of the disease, till explained by the operation. He also mentions a case in which a large tumour in the scrotum lay behind the testicle, but quite distinct from it, and gave the impression of being an omental hernia,• it was, however, determined to operate on it, and it was then discovered to be a fatty tumour connected with the spermatic cord within the abdominal ring, which as it had grown, descended into the scrotum, (p. 271.) Among the Tarest situations of fatty tumours, the tongue may be;mentioned: in the Museum of the College of Surgeons there is a specimen of a small lobulated fatty swelling which had been removed from that organ.] 2245. The causes of fatty tumours are unknown. Rarely can they be ascribed to pressure, blows, or any other violence. They are seen at all ages and in both sexes, though most frequently in adults; they seem also to be more frequent in females, though without any relation to menstrua- tion. They generally occur on the shoulders, upon the back and on the neck ; but are, however, observed on other parts, and even on such as have naturally very little disposition to fat. Oftentimes several fatty tumours occur, even in considerable number in the same individual. Not unfrequently is a fatty tumour congenital, aud then often acquires considerable size; in this case too, sometimes the general coverings are more or less altered, loosened up, dusky coloured, beset with large quantities of and longer hair than natural. Such have been named by Walther fatty mother marks (Nevus matemus lipomatodes, Lat.; Fettmuttermahl, Germ.) The disease also usually spreads after birth to a considerable extent. 2246. Fatty tumours are always to be considered important diseases, as (a) Compare also Vogel, above cited.— (c) Lectures on Surgery; in Lancet. Heyfhxder, De Lipomate. Commentatio 1829-30; vol. i. p. 869. loco in Facultate Medicorum Univers. lit. (d) Omodei, Annali Universali, vol. xxviii. Erlang. rite obtinendo. p. 343. 1823. (b) Med.-Chir. Trans., vol. xi. p. 440. 1624. OPERATION FOR THEIR REMOVAL. 429 they enlarge very quickly, spread and run into ill-conditioned ulcers (1). Small swellings may indeed in many instances be dispersed by the application of gum ammoniac dissolved in vinegar of squills, by rubbing in ox gall, nut oil, and liquor of acetate of ammonia (2). Their removal with the knife is, however, generally the only certain mode of treatment. This operation is easy and without any danger in those fatty tumours which have a broad base; but it may be difficult and dangerous if the swelling be of great extent, lie in the neighbourhood of important parts, or if it have deeply-stretching roots. Under these circumstances, it is Viot often possible to remove all the degeneration, even with the greatest care, so that either the fatty growth begins anew, or a long-continued ill conditioned suppuration ensues, and even fistulas, which remain through- out life. Not unfrequently the general formative action appears to be increased by the operation, as often not only in the neighbourhood of the part operated on, but also in distant parts, where previously no lipoma had existed, it sprouts fourth. It must also not be forgotten, in reference to the performance of the operation, that many lipomata are so con- siderable, and so largely penetrated with branching vessels, that the operation is attended with considerable bleeding (3). [(1) As regards ulceration, Brodie observes:—"The skin over a fatty tumour very rarely inflames and ulcerates. You might a priori expect that the pressure of the tumour would often produce this effect, but it is not so. I have, however, known inflammation to take place in the substance of the tumour, and an abscess to form irt its centre." And he mentions a case in which this happened in a large tumour on the back; "the abscess never healed, but continued to discharge profusely matter with an oily fluid floating in it," till the swelling was removed, (p. 273.) He also refers to Astley Cooper's opinion, that "a fatty tumour Will sometimes take on the action of a malignant disease, and become a malignant tumour," and is inclined to agree with it in consequence of a case which he operated on, "composed of what seemed to be fatty substance, somewhat more condensed than usual; but that here and there, dispersed throughout the mass, there was another kind of morbid growth, apparently belonging to the class of medullary or fungoid disease. It is reasonable to suppose that if this tumour had been allowed to remain, it Would have ulcerated, and run the usual course of a malignant disease." (p. 282.) (2) In the case of diffuse fatty tumours of the neck, already referred to, (p. 690,) Brodie " gave half a drachm of the liquor potassae three times a day, and gradually increased the dose to a drachm, dissolved in small beer;" the result of which, after some time, was, that considerable absorption of the swelling occurred, though "there were still some remains of the tumour, but nothing that was very remark- able. I have seen" he observes, "some other cases in which the exhibition of very large doses of the liquor potassae appeared to be of great service." (p. 276.) For the more common circumscribed fatty swellings, there is not, as far as I have had opportunity of seeing, any remedy to produce their absorption, Whether they be small or large, and therefore to be got rid of, they must be removed by the knife. It is not needful, however, to meddle with them if their size do not inconvenience the patient, and so long as they remain stationary, which they often will for years, But if they at any time begin to increase, they should be at once removed, as when this action begins, it generally continues more or less quickly. (3) Easy as the removal of fatty tumours undoubtedly is, it not unfrequently hap- pens that there is a good deal of boggling from inattention to the simple circum- stance of cutting through the cellular c^st surrounding them, to the extent of the external wound, and fairly into the fatty tumour itself. If the cyst be thus opened, the operation may generally be completed by running the finger or the handle of the knife between it and the. tumour, which usually turns out like a kernel from its shell, being only here and there held by little processes of cellular tissue, or little bundles of vessels, which are best torn through, or if too tough and large to admit this, must be cut with the knife. If, however, the cyst be not opened, the tumour Vol. iil—37 430 ENCYSTED TUMOURS. will not turn out, and must be fairly dissected out with the knife, which is very tedious and inconvenient, as almost every little vessel divided bleeds freely and requires tying, the fortner of Which does not happen, and the latter is therefore unnecessary, if the tumour be torn from its cyst, which is an additional reason why this method should be preferred. It occasionally happens indeed, that after the removal of the tumour in this manner, the cavity suppurates and heals by granula- tion; but this is matter of little consequence, and only slightly retards the cure.— j. f. s.] 2247. The removal of lipoma is managed according to the same rules laid down in regard to encysted tumours. Ihe wound may be brought together, if the base of the lipoma be not large, and the whole has been completely removed, and united by quick union. But in large lipomata, which cannot be cleanly turned out, when the wound has been brought together, only an imperfect union of the skin with the corresponding sur- face of the wound is produced ; as at eveiy part where little bits of fat remain, union does not take place, a fatty purulent l)mph flows out; and, if its escape be prevented, inflammation of the skin, bursting again of the united parts, continued ill-conditioned suppuration, and fistulas, remain- ing even throughout life, are produced (1). After the removal of diffused lipoma, therefore, the edges of the wound are to be kept apart by proper dressing, till the discharge has lost its oily character, and healthy sup- puration is set up; and then the Cure is to be promoted by bringing together the edges of the wound. When the swelling is penetrated by a great many vessels, or its roots cannot be removed by the knife without great danger, it may be necessary to apply a ligature around its base, which must be isolated as much as possible, and the swelling cut off beyond it. Under these circumstances, the destruction of the remaining substance,, by the use of escharotics, is exceedingly difficult, and even impossible (a). The employment of a seton for the removal of lipoma, is only fitting when the extirpation is impossible. This method, however, is always extremely uncertain, as the swelling either does not go away, or soon recurs. [(1) I have never seen the inconveniences to which Chelius here alludes, which may certainly be prevented by attention in properly dressing the wound, and the application of compresses, on any part where there is a disposition to bagging of the pus. As a general rule, it is also advisable to follow the roots of the tumour, should they spread out as they occasionally do; but sometimes this cannot be managed without doing mischief, by disturbing important parts ; it is then best to tear through these roots, as far in as possible, and usually in the course of the cure they suppurate and disappear.—j. f. s.] X.—OF ENCYSTED TUMOURS. (Tumores cystici, sacculi, tunicati, Cystides, Lupiae, d^c, Lat.; Balggeschwuktc, Sackgeschwulste, Germ.; Tumeurs enkystees, Fr.) Salzmann, De quibusdam Tumoribus tunicatis extends. Argent., 1719; in Haller's Disputationes Chirurgicae, vol. v. p. 383. Girard, Lupiologie, ou Traite sur les Tumeurs connues sous le nom de Loupes. Paris, 1775. Chopart, Essaies sur les Loupes; in Prix de l'Academie de Chirurgie, vol. iv. p, 274. Chambon, Memoire sur les Loupes; in Prix de l'Acad. de Chir., vol. v. p. 332. (a) Schreger, above cfted. KINDS OF ENCYSTED TUMOURS. 431 Jacobson, (Praeside Loder,) Dissert, de Tumoribus cysticis. Jena?, 1792. Loder, Ueber die Balggeschwiilste; in Chirurg.-Medic. Beobachtungen, vol. i. p. 205. Weimar, 1794. Bichat, Traite de Membranes, p. 181. JNew Edition by Hasson. Paris, 1816. Jaeger, M., Ueber Balggeschwiilste; from the Encyclopaedische Worterbuchder Medic. Wissenchaft, vol. iv. p. 634. Berlin, 1830. 2248. Encysted Tumours are swellings developed in the cellular tissue of the skin, or in the interstitial cellular tissue of other parts, and charac- terized by a proper membrane being formed, in the cavity of which there is a secretion of a peculiar substance. That this membrane does not result from expansion and thickening of the cellular tissue, but must be considered as a new formation, which, in reference to its nature and its vital peculiarities, agrees with serous membranes, has been clearly shown by Bichat. The circumstance, that a cyst is formed around foreign substances accidently introduced into the body, dose not controvert this opinion : as this cyst, manifestly originating from pressure on the cellular tissue, is not a peculiar secreting organ. Meckel (a) may be consulted in opposition to the opinion advanced by Adams (b), that all encysted tumours are to be considered as animals of the lowest kind, to wit, as hydatids. [(1) With reference to the formation of cysts around foreign substances, John Hunter (c) speaks of it as an example " of Uie deeper seated parts not so readily taking on the suppurative inflammation as those which are superficial; * * * for we find that extraneous bodies are in general capable of producing inflammation; but if these extraneous bodies are deeply seated, they may remain for years, without doing more than producing the adhesive inflammation, by which means they are inclosed in a cyst, and only give some uneasiness."—(pp. 238, 39.) An example of this kind I recollect having seen several years since. A medical student in Paris had, for want of better employment, mixed himself up with some popular dis- turbance, to quell which the military were called in, and he received a wound in the buttock, which soon united, but left some uneasiness and a defined swelling. About three years after, I saw Dupuytren, at the Hotel Dieu, cut into this tumour, from which a quantity of glairy fluid escaped; and the finger being introduced into it, about an inch and a half of a sabre-point was felt and removed. But the lodgement of an extraneous body without producing suppuration is not confined to deep-seated parts; for Hunter, very shortly after observing in regard to pins and needles, which, when having been introduced into the body, are well known, in general, not to produce suppuration, but either lie quietly in one place, or move over the body to an almost incredible distance from the point at which they had entered : that "they owe their want of power in producing suppuration, not entirely to situation, but in some degree to the nature of the substance, metals, perhaps, not having the power of irritation beyond the adhesive; for when the adhesive has taken place, the part appears to be satisfied;" he continues, " this appears also to be the case with the introduction of glass, even in the superficial parts; a piece of glass shall enter the skin, just deep enough to bury itself, inflammation shall come on, the wound in the skin, if brought together, shall heal by the first intention, and the inflammation shall not exceed the adhesive, but rather degenerate into the disposition tor forming a sack, by which means a sack is formed round the glass, and no disturbance is given to the irritability of the parts.".—(pp. 239, 240.) Besides the example which Hunter mentions, in proof of this latter statement, I may refer to the case of the tobacco-pipe in a man's cheek, whieh I have already mentioned (p. 380;) and there is in the Museum of the Royal College of Surgeons a portion of a glass mirror, which by a fall was driven into a girl's breast, and there remained for many weeks, without exciting suppuration. These examples prove, and even from his own show- ing, that Hunter's first statement, of "deep-seated parts not so readily taken on the (a) Handbuch der Patholog^chen Anato- (6) Olservations on the Cancerous Breast. mie, vol. ii. part ii. p. 13-'. London, 1801. 8vo. (c) On the Blood, Inflammation, &c. 432 CAUSE AND NATURE suppurative inflammation as those which are superficial," is not borne out. Nor has it yet been explained, how it is that foreign bodies do become encysted, rather than set up suppurative inflammation, by which, as under common circumstances, they are expelled from the body.—j. f. s.] 2249. Encysted tumours are distinguished according to the consistence and nature of the substance contained in their cavity, as, first, Serous Cysts {Cystes serosa, Hygroma, Lat.; serbse Balggeschwiilste, Germ.; Loupes sereuses ou aqueuses, Fr.) (1); second, Melicerous Tumours, (Melicer\s, Lat.; Honiggeschwiilste, Germ.; Loupes meliceriques, Fr.,) when the contained substance is of the consistence of honey (2); third, Atheromatous Tumours {Atheroma, Lat.; Breigeschwulste, Germ.; Loupes otheromateuses, Fr.,) when it resembles pap (3). To these kinds of encysted tumours Abernethy (a) adds a fourth, in which the cavity is filled with nail or horn-like substance, which, when the skin breaks hardens, and projecting, as the cyst continues to secrete, forms a horn- like growth (4). [(1) Simple serous cysts, on the exterior of the body, are not of frequent occur- rence. When existing in the neck they are commonly called "Hydroceles of the Neck," under which name they were first described by Maunior (b), who mentions that the disease had been confounded with bronchocele, on account of its external characters, and had been noticed without knowledge of its real nature by Heister, Plouquet, and Petit. " It consists," he says, " simply of a collection of serous or lymphatic fluid; * * * it is an affection sui generis, tolerably frequent, and not as has been supposed a rare and unusual form of bronchocele." (p. 95.) Cases have since been described by Dr. O'Beirne (c) and by Bransby Cooper (d). They com- monly originate in the lower part of the neck, just above the collar-bone, of small size, but increases in bulk, covering the whole of that side, and even running across beneath the skin. Sometimes, however, they make their first appearance below the lobe of the ear, and get attached to the angle of the jaw. As they increase in size they interfere with swallowing and breathing, so as to cause severe cough and symp- toms of suffocation. Fluctuation is distinctly felt, but they are not always trans- parent, as though sometimes the fluid they Contain is clear and limpid, it is more frequently either like Goffee or coffee grounds, which probably depends on the rup- ture of some little vessel into their cavity, under the exertion of soughing. Maunoir thinks that the cyst is thicker than in hydrocele of the testicle; and in one of the cases mentioned by Fleury (e), it was very hard and resisting, and its interior lined with a fibro-cartilaginous covering. In the Museum of the College of Surgeons, there is a specimen of one of these serous cysts removed from the front of the neck by Thomas. Blizard ; it is more than six inches in diameter; its walls thin and fibro- cellular; a portion of it passed behind the collar-bone, and it contained a clear brownish fluid. Also, another attached to the back of the tongue-bone, about two inches in diameter, which contained a brownish yellow, thick grumous, honey-like fluid, containing abundant crystals of cholestearine. Simple cysts are rare in the female breast, Brodie says he has seen but two; and in the Museum at St. Thomas's there is another. Perhaps here also belong Astley Cooper's (/) cellulous hydatids of the breast, of which, however, there are generally several in the same gland, as in the specimens in the College Museum. In the same collection there are also examples of a large cyst removed from the thigh, and of another which filled up the thyroid hole, projecting both into the pelvis and the thigh, and followed a kick on (a) Above cited, p. 113. Medical and Chemical Science, vol. vi. p. I. {b) Memoires sur les Amputations, l'Hy- 1834. drocele du Cou, &.c. Geneve. Paris, 1825. (d) Case of Hydrocele of the Neck cured The Memorial was read before the French by Seton, with Observations; in Guy's lnstitut in 1815: but the report upon it by Hospital Reports, vol. i. p. 105. Percy was not favourable. (e.) Annales de Chirurgie, vol. -\. p. 377. (c) On Hydrocele of the. Neck, with Cases 1844. and Observ.atiqn.i; in Dublin Journal qf (/) Illustrations of Diseases of the Breast London,.1629. 4to. OF ENCYSTED TUMOURS. 433 the part; both these cases were from females (a). A few years since I had a patient with a cyst on the auricle, which contained a thick brownish, but transparent glairy fluid ; this filled again several times after being punctured, and was cured at last by stuffing with lint, and causing suppuration of ihe sac. (2) It is probable that these so-called melicerous cysts merely differ from the former in the thicker nature of their contents. (3) Atheromatous cysts sometimes contain a pultaceous white matter, like pap; or, as Home (6) has described it, "a small quantity of thick curd-like matter, mixed with cuticle, broken down into small parts." (p. 101.) Some such examples exist in the College Museum, stated in the Hunterian manuscripts to consist "principally of a series of cuticles thrown off," and "a flaky substance, which seemed to be a succession of cuticles, being the same with that which lines the oyst." Home also observes:—"Other cysts of this kind, instead of having cuticle for their contents, are filled with hair, mixed with a curdled substance, or hair without any admixture whatever, and have a similar kind of hair growing upon their internal surface, which is likewise covered with a cuticle." (p. 102.) I have seen in two or three instances these cysts filled with little bodies, semitransparent, and resembling grains of boiled rice flattened and packed closely together, which were probably scales of cuticle. Even teeth, more or less perfectly formed, have been found in a cyst in the orbit, as happened in a case related by Barnes (c) of Exeter. (4) These are true productions of the sebaceous follicles, and have been already mentioned (par. 2198, note) in speaking of Horns.] 2250. The nature of the cyst is very various, and has no connexion with the size of the swelling. In those which contain serous fluid the cyst is generally thin and correspondingly transparent. The cyst is often very firm, tough, fibrous, may be separated into many layers from the outer surface, and often has an almost horny character. At many parts it is frequently found bony. The inner surface of the cyst is often smooth and shining; frequently has a velvet-like surface; is sometimes beset with true hairs; oftentimes it exhibits rather a muco-membranous struc- ture, an irregular, folded, net-like surface. The connexion of the cyst with the surrounding paits is usually but slight, by means of delicate cel- lular tissue and few vessels; sometimes, however, a very firm connexion is found, and the cyst cannot be well distinguished from its immediate investments. [" Mr. Hunter considers the internal surface of the cyst to be so circumstanced respecting the body, as to lose the stimulus of being an internal part, and to receive the same impression from its contents, either from their nature or the length of ap- plication, as the surface of the skin does from its external situation. It therefore. takes on actions suited to such stimuli, undergoes a change in its structure, and acv, quires a disposition similar to the cutis, and is consequently possessed of the power of producing cuticle and hair. What the mode of action is, by which this change is brought about, is not easily determined ; but from thesindolenoe of these com- plaints, it most probably requires a considerable length of time to produce it. That the lining of the cyst really does possess power similar to cutis, is proved by the following circumstances ; that it has a power of forming a succession of cuticles like the common skin, and what is thrown off in this way is found in the cavity of- the cyst. It has a similar power respecting hair, and sometimes the cavity is filled with it, so great a quantity has been shed by the internal surface." It is further added :—" What is still more curious, when such cysts are laid open, the internal surface undergoes no change from exposure, the cut edges cicatrize, and the bottom, of the bag remains ever after an external surface. Different specimens of the above-mentioned circumstances are preserved in Mr. Hunter's collection of dis- eases." (d).} (n) Facet's Catalogue of the Pathological crescences of the Human Body; in Phil. Collection in the Museum of the Royal Col- Trans., vol. lxxxi. p, 95. lege of Furgeons of England. (c) Med.-Chir. Trans., vol. iv. p. 316. 1813^ (b) Observations on certain Horny Ex- (d) Home, above cited, p. 102. 37* 434 ENCYSTED TUMOURS. 2251. Encysted tumours are at first always small, and developed slowly to a large size. Their form is generally round, and their extent well defined, if the surrounding parts do not affect their development in a decided direction. They are moveable at their base; this, however, depends on the yieldingness of the parts surrounding them, and on their firmer or looser connexion with them. The manner in which an en- eysted swelling is filled differs, according to the nature of the contained substance and of the cyst; the swelling is elastic, expanded and yield- ing ; a distinct fluctuation is often felt; sometimes it is firm; the skin eovering it is unchanged. An encysted tumour, when it has reached a certain size, often remains stationary throughoutlife, sometimes it continues increasing slowly. Various symptoms may be produced by the pressure of the swelling upon important neighbouring, parts ; if or* a laone it will destroy it by continued pressure. Nutrition may also be interfered with by several encysted tumours., 2252. Sometimes, in consequence of external violence or from un- known causes, the encysted tumour inflames, and pours into its cavity a puriform fluid; The external skin reddens, and ulcerates, the cyst Bursts, and the fluid contained in its cavity is discharged. If the in- flammation be-severe, the menabrane forming the sac is loosened into Gellular tissue^ thrown off, and thus a perfect cure«is effected. But this part often remains ulcerated, and very sensitive ; an ichorous ill-condi- tioned pus continues to be discharged'; fungous growths spring up, and the aperture obstinately resists healing.. 2253. Encysted tumours are to be considered consequences of an un- natural formative effort, of which the- proximate cause is, in most cases, not to be determined. They are frequently congenital, and then form a peculiar kind of nevus?, maternus; sometimes they are hereditary; fre- quently arise in consequence of rheumatic, gouty, syphilitic, or scrofu- lous disease ; sometimes from external violence, continued pressure, and the like. They may occur on all parts of the external surface of the body, but are most commonly developed' where naturally the cellular tjssue is in largest quantity. 2254. A peculiar kind of encysted tumour-, which most commonly occurs under the skin of the head' and'face, and upon the back, though but rarely ins other, parts, has been subjected to particular inquiry by Astley Cooper (a), who has fixed its origin in the obstruction of a se- baceous,, follicle of the skim, in which case the tallow-like sebaceous matter collects in its cavity, and its walls expands in the cellular tissue {Tumor sebaceus.) The form, of this swelling is mostly globular; it feels firm upon the head, but on the face fluctuates indistinctly. It often presents, at the beginning, a dusky spot in its middle, which is the plugged-up mouth of the follicle, and'from which the contained matter may oftentimes be squeezed (1). When it has attained its ordinary ,siz,e,,from.-;one to two inches in diameter, it sometimes suddenly sub- sides, again begins, increases, and' acquires its previous size. It con- tains a substance similar to coagulated albumen, which, when the tu- fa) Astley Cooper^; in his and Travers's lipsise, HfiS.—von Walther, Ueber die Surgical Essays, part ii. p. 229—Bae«sgh, Balggeschwiilste; in Journ. fur Chirurg. (Proes.. Reichel,") Dissert, de Tumaribus und Angejiheitk, vol; iv-p. 379. Capitis tunicatis post; Cephalagiam exortis. SEBACEOUS TUMOURS. 435 mour suppurates, stinks horribly. It is rather less moveable than the com- mon encysted tumours, and is more firmly connected with the skin. Sometimes the cyst contains hair; sometimes the swelling ossifies (2.) Horny excrescences frequently spring from these tumours ; the horn be- gins growing at the open part of the cyst, is at first soft and flexible, but soon acquires considerable hardness, and assumes the nature of horn (a). The structure of the cyst varies; on the face it is usually thin, thicker on the back, and thickest on the-head; it also acquires greater thickness in proportion to the length of time it has existed. On its in- terior the cyst is lined with an epidermis. When bodies have been artificially introduced, the cyst presents many but minute vessels. Pres- sure is a frequent cause of this swelling-; also a diseased state of the secretion, a deficiency of its wonted fluidity, a thickness of the substance secreted in the follicle, and flaccidity of its walls. I have seen a consi- derable number of such swellings after the suppression of an eruption on the head. They frequently seem to be hereditary. [(1) The most simple form of sebaceous tumour, or, more properly speakings Sebaceous accumulations, as they are oalled, by Erasmus Wilson, (b,) is that com- monly seen on the sides of the nose, and also upon the face in unhealthy persons, and not unfrequently on the shoulders and back, often in very considerable number, varying in size from that of a pin's head to a pea, the tops of which becoming blackened, have given rise to their vulgar name " black heads." Sometimes they lie quiet, giving to the face a dirty ugly appearance ; but if a gentle pressure be made on either side, the substance of which they consist oozes out like little yel- lowish white worms or maggots, by which name they are also not unfrequently called, various length and size, according to the length and distension of the sebaceous fol- licle. Sometimes they acquire considerable size ; Astley Cooper mentions that he himself had one on the lower part of the dorsal vertebrae, which had acquired a dia- meter of about two inches, and had a small black spot in its centre, which having been picked off, he squeezed out a large quantity of sebaceous matter. Sometimes these collections, not being rubbed out, as they frequently are after washing, or not having been purposely squeezed out, inflame the follicles,.and thus acne is pro- duced, which commonly terminates in suppuration, covering the face and back with repeated crops of pimples, especially annoying-to females. Astley Cooper considers the encysted tumours-formed on the head and back to arise merely from obstruction of the sebaceous follicles, and this opinion is generally held. But I have great doubt of its correctness, for such cysts are always complete sacs, without the least appearance of ever having had any opening ; they may be rolled about very freely beneath the skin, to which they are so loosely attached, as well also as to the cellular tissue, that after cutting carefully through the skin, they may generally be shelled out by running a probe around them, unless having by their size irritated the surrounding parts, they have become adherent to them, and specially to the skin, which by degrees yields to their pressure, and ulcerating, they burst, as the cyst itself, though sometimes as thick as a shilling, tears very easily, and may be split into flakes resembling recent fibrin. If left to themselves, after bursting, these cysts produce troublesome sores, which continue till the cyst either comes away or is pulled away piecemeal, and then, the sores heal. But no- thing of this kind happens when the swelling is formed by an obstruction of the mouth of the follicle; the follicle either yields to the accumulating sebacin, and enlarges till, as in Astley Cooper's own case, it acquires considerable size, but can be emptied by gentle pressure-of its contents, and nothing further happens be- yond the recollection of the sebacin. Or the follicle inflames and suppurates, forcing out with the pus the little mass of hardened sebaceous matter, after which the ir> flammation quickly subsides, and the follicle resumes its natural office, without,' however, any thing which has the least pretension to a cyet having been discharged. It, therefore, seems to me that from the different courses these two forms run (a) This subject Ins been already considered in treating of Horns. (6) Above cited. 436 CURE OF ENCYSTED TUMOURS BY DISPERSION. through, they are of decidedly different nature. To this it may also be added, that the tumours resulting from obstruction of the follicles, have occasionally their con- tents converted into a projecting horn, in the way which Erasmus Wilson has de- scribed, as already noticed ; but so far as I am aware this never happens when the cyst is globular, close, and of the recent fibrous character, which I have noticed and which is almost invariably seated in the scalp.—j. f. s.] (2) The ossification of an encysted tumour or of its contents is very rare; Dal- rymple (a), however, has mentioned an example of "a small tumour, which he removed from beneath the tarsal cartilage of the upper eyelid of a middle-aged man, which instead of the usual cheesy matter contained an apparently earthy or bony deposit. This tumour was somewhat larger than a pea, and composed of concentric layers of hard earthy material, and in form, was rounded, except at the surface im- mediately behind the conjunctiva, where it was somewhat flattened and rough. * * * Upon examination by the microscope, the concentric layers of this tumour were found composed entirely of epithelium scales, closely agglutinated together; but instead of the usual transparent and thin lamina with its central nucleus, they were thickened and hard, and contained granular earthy molecules, which could be removed by immersion in weak muriatic acid. No amorphose earthy deposit existed around or among the scales, but the whole was composed of this epithelium opaque, of a light-brown colour, with a clear and large central nucleus." (pp. 238, 39.)] 2255. To encysted tumours Ganglia {Ueberbeine, Germ.) are allied; they are round, of slow growth, rarely exceeding the size of a pigeon's egg, and in general, consisting of thick walled cavities, developed in the neighbourhood of joints and sheaths of tendons, containing a fluid similar to synovia, with a greater or less number of little white cartilage-like bodies; in some cases, they must be considered as partial expansion of the tendon sheaths, but more generally as actually new productions (b). They commonly arise from external violence, pressure, violent straining of a tendon and the like, on which account they are most frequent on the back of the hands and feet; in some instances, they seem to originate from constitutional causes. As long as the swelling is small, it produces no inconvenience; but when it acquires large size, it inteiftres with mo- tion; and if it inflame and suppurate, tiresome ulcers are produced (c). 2256. The cure of encysted tumours is effected in various ways, the choice of which depends on their seat and size, their mode of connexion with the neighbouring parts, their mobility or immobility, the nature of the coverings of the swelling, and the excitability of the patient. These modes oftreatment consist, first, in the dispersion of the swellin (a) Von. den Krankheltpn der Gesichtsknochen,,p. 23. IN THE MEDULLARY SINUS. 283 mends as especially advantageous, diluted tincture of capsicum, and solution of nitrate of silver. [The restoration of the original aperture between the maxillary cavity and the nostril, is not of the slightest consequence; at least, so far as the cases I have seen, prove. Weinhold's notion, I do not think, is any thing worth, or at all likely to be correct, for as soon as the pus has escaped by the hole in the tooth-socket, the in- flammation subsides, and the lining of the maxillary cavity resumes its natural function. But if the pus have been very long pent up, and the mucous membrane destroyed, it is more probable there will be exfoliation of the bony walls, than that the whole cavity will be filled with granulation. I have not, however, seen any case where either one or other such result has occurred. Weinhold's recommenda- tion of injecting stimulating solutions cannot be too strongly deprecated, as being fraught with mischief, and should never be followed. It is not, however, objection- able to inject warm water for two or three days after the tooth has been drawn, and the cavity tapped, as thereby it is more quickly cleansed, and the healthy processes are encouraged.—j. f. s.] 2358. Boring into the maxillary cavity in the fossa canina is indicated when the teeth and alveolar process are healthy, in collections of fluid, and polypous and other degenerations. The patient sitting on a stool, his head is fixed by an assistant against his breast, and the corner of the mouth on the affected side drawn down with a blunt hook. The cheek is to be separated at the front edge of the base of the zygomatic process, in the direction of the second or third molar tooth, by a cut through the gum ; the periosteum is to be cut through cross-wise, and the flaps cut off with scissors. Upon the bared bone a perforating trephine is then ap- plied and made to penetrate rather obliquely from below upwards through the wall of the maxillary cavity. An examination is made with a probe to ascertain whether there be any after-production, and if there be, to what extent this hole should be enlarged. If necessary, it must be widened first with the pointed and afterwards with the blunt perforator; and if the wall be soft, this may be done with a strong curved knife; and the opening should always be made sufficiently large to introduce the finger. A small-crowned trephine may also be useful in perforating the cavity at this part (a). 2359. The further treatment is guided by the state of disease. In blennorrhoea and ulceration the same proceeding is adopted, as after per- forating the tooth-socket. Any after-products existing in the maxillary sinus must be removed according to their nature, by cutting away, tear- ing off, tying, or by destroying them with caustic. 2360. Cutting away cannot be employed if the polyp have a broad base, as there is always then danger of severe bleeding, and recurrence of the disease. The polyp is to be drawn well forward, and cut off with the bistoury, or with Cooper's scissors: the bleeding must be stanched with wadding moistened or strewed with styptics and pressure, or by the application of the actual cautery. , Tying is rarely possible, and tearing off the polyp with straight or curved forceps, having grasped it as near as possible to its root, is always to be preferred. Destruction with caustic is only proper when the disease cannot be got at in any other way. For this purpose, butyr of antimony, caustic potash, or best of all, lunar caustic, are employed ; a strong solution of the latter, on lint, being introduced into the cavity. (fy Desault, above citedj vol. ii. p. I66,>pl. ii figs. 1, 2, 3. 484 TREATMENT OF POLYPS The actual cautery is only to be employed when the other remedies are fruitless, and even then with great caution. For this purpose, a metallic tube, wrapped in wetted linen, is passed into the opening up to the midst of the after-product, and a trocar, at white heat, thrust through it. If the unnatural vegetation he by these means stopped, and'if hard granu- lations sprout up, they may be treated with astringents till1 the scarring is completed. 2361. The object of boring into the maxillary cavity below the eminen- tia molaris, and above the third or fourth molar tooth, is the same as that for boring in the fossa canina; and the indications are also the same. The patient having been placed as already described, and the corner of the mouth drawn down, the gum and periosteum are divided at the part determined, and the bony wall is bored obliquely from below upwards, and from without inwards, with the perforator. The further proceeding is the same as in boring in the fossa canina. 2362. Boring into the maxillary sinus through the palate, when the palate is much altered by disease, and another situation cannot be con^- veniently chosen, or at any one part, where the cavity is very thin or burst through, is easily managed from what has been already said on the different modes of boring; the after-treatment is also guided'by the same rule. 2363. For boring into the maxillary sinus upon the cheek, Weixhold proposes several' modes of proceeding. If the disease be bt'ennorrhcea, and loosening up of the mucous membrane, with narrowing and closing of the aperture, in which the object is to do away with the secretive ac- tivity of the mucous membrane, the needle-trephine (a) must be applied on the bone, and an aperture made, rather obliquely upwards, through the distended cheek into the maxillary sinus, four lines from the zygo- matic process towards the nose, and the same distance from the lower edge of the orbit, and then as it is rotated, the front wall of the cavity is pierced. The perforator may also be appliedwitb the same purpose, but instead of the needle-trephine after having cut into the cheek. A plug is then introduced into the opening, and1 fastened to the temple by a thread; it may also afterwards be smeared with red precipitate oint- ment, and a solution of nitrate of silver, or properly diluted tincture of capsicum may be injected, till the-mucous membrane is destroyed {par. 2357.) 2364. If the after-products, polyps, steatomes, fatty growths and the like, or the secretion of the mucous membrane are to be destroyed, the needle-trephine armed with a thread in its eye should be introduced at the appointed'place, and whilst the handle is a little raised, the point is carried so downwards through the maxillary sinus, that it penetrate the palate some lines distant from the third molar tooth. In doing this, the tongue is to be protected1 from the injury by the forefinger of the left hand, and the point of the trephine thrust so far out, that the thread in its eye can be reached with a hook. The trephine is now withdrawn; and the thread left behind, by which either a firm cord or a plug of tape is introduced, and these are to be smeared with remedies proper for de^ stroying the after-products. In fatty swellings the string should be fre- (a) Ideeruuber die. krankhaften Metamorp'iosen der Highmorshohle, fig. 1. IN THE MAXILLARY SINUS. 485 quently drawn backwards and forwards, and moistened with oil of tur- pentine, and as much as possible of the mass removed with Daviel's spoon. For the destruction of polyps or sarcomatous degenerations, the plug should be smeared with a solution of lunar caustic, of bichloride of mercury, with red precipitate ointment, and the like. To prevent the acrid fluid escaping into the mouth, to that part of the string hanging in it a thread should be attached, and whilst the upper part of the string is pulled up, the thread must be drawn through the upper opening of the cavity, and separated from the string. To the lower part of the thread a piece of sponge or a wad of lint is attached, which must be pressed firmly against the opening in the palate, whilst the upper end of the thread is pulled up. The upper part of the string is then smeared with some of the just-mentioned escharotics, and replaced in the sinus. If the string be gradually made thicker, it favours the cure. According to Hedenus, the seton, after the lip has been separated from the upper jaw, should be drawn within the mouth through the front wall of the maxillary sinus and the palate, by means of a curved needle (a). 2365. In deciding on the different modes of proceeding for opening the maxillary sinus, it must be remembered that in collections of mucus and pus, when there are also caries and necrosis of the alveolar process, and of the walls of the sinus, the principal object must always be to form a sufficiently large opening, so that the collected fluid may freely escape, and the loose pieces of bone be removed. For such cases, under the circumstances above mentioned, {par. 2356,) boring through the tooth-socket or in the fossa canina is best. The introduction of a seton according to Weinhold's method is very advantageous for destroying many after-growths. There are, however, degenerations of the maxil- lary sinus, in which not merely the mucous membrane, but even the bones are completely changed in their tissue, to which neither of the above-mentioned modes of treatment are applicable ; and the removal of the after-products is alone possible by taking away the greater part of the bony wall so as to get at them ; or the bone may be divided to the whole extent of the after-product, as will be directed for the removal of the upper jaw. As to the special performance of this operation, nothing decided can be laid down; it must depend on the peculiarity of the case, the circumstances allied to which will be hereafter noticed, in treating of removal of the upper jaw. In the former case it must be attempted to penetrate the front wall of the sinus by a semicircular cut above the alveolar process with a sickle-shaped knife, and by a like cut through the palate also, so as to cut out an elliptical portion of the bony wall. The after-product must now be removed with polyp-forceps, or if its adhesions be firm, it must be taken away with the knife. The bleeding during this operation is always severe, and requires, if pressure with wads of lint be insufficient, the actual cautery; this is best ma- naged with a bent trocar, of which the canula is wrapped in wet linen. The actual cautery should not be applied very smartly to destroy the after-product, because it may produce severe and dangerous reaction. At first, after the operation, the treatment must be antiphlogistic and soothing according to circumstances. When suppuration is set up, it must be sustained by smearing the lint with digestive, and strewing it (a) Graefe und Walther's Journal, vol. ii. part. iii. p. 387.—Weinhold, in same, vol. iii. part i. 486 POLYPS OF THE WOMB AND OF THE VAGINA. with irritating powders. If all the after-product be not removed, or if it be not destroyed by the actual cautery, and a new growth ensue, it must be destroyed by escharofics, of which nitrate of silver is best. It is self-evident that in this local treatment, the state of the powers and any causal dyscrasy must not be forgotten, but met with corresponding treat- ment. In consequence of a diseased tooth, its root may expand the surrounding socket, and form a pretty spacious cavity, unconnected, however, with the maxillary sinus. Drawing the tooth, and removal of the front wall of the socket, are sufficient for the cure. After the removal of teeth, the roots of which extend into the maxillary sinus, fistulous openings often remain between them, through which occasionally some saltish fluid escapes into the mouth ; if left alone, these fistulas are of no conse- quence. 2366. The same diseased conditions which render the opening of the maxillary sinus necessary, may also require the frontal sinuses to be opened, as their mucous membrane is subject to the same changes as that of the maxillary sinus. In boring into the frontal sinus, the bone is to be laid bare at that part where it is most expanded, and the external plate penetrated with a trephine. The after-treatment must be con- ducted according to the nature of the disease, just as after opening the maxillary sinus. A peculiar affection of the maxillary sinus must be here mentioned, which has been specially noticed by Dupuytren, consisting of a development of a cellulo- fibrous swelling, enclosed in a proper cyst, besides the mucous lining of the cavity. This tumour, of which the consistence varies according to its age, if examined, presents in its structure an approach, to that of a fibrous polyp, but does not seem, to have any great disposition to cancerous degeneration. At first it is little inconve- nient; as it grows it distends the walls of the sinus, especially in front, and thins them so that they form merely a thin plate which is yielding, gives way to pressure, and by its elasticity rises again with a sort of crackling, like that produced by pressing a bladder half filled with air. This symptom, which is pathognomic, fades away after repeated examination. A cut from the infra-orbitary hole to the corner of the mouth lays bare the distended wall of the bone, and with a common bistoury a sufficiently large opening, or even a crucial cut, may be made into it. The swell- ing may be seized with a hook, or with Museux's forceps, and easily pulled out. It is, however, very difficult to get out the cyst at the same time, and therefore, in most cases, it is necessary to stuff the cavity with lint, and to destroy it by inflame mation and suppuration. A moderate degree of pressure will assist the return of the bony walls to their place (Pigne.) D.—OF POLYPS OF THE WOMB AND OF THE VAGINA. Levret, above cited. -------, Sur les Polypes de la Matrice et du Vagin; in Mem. de l'Acad. de Chirurg., vol. iii. p. 518. Herbiniaux, Parallele de Differens instrumens et methode de s'en servir, et de pratiquer la ligature des Polypes dans la Matrice. A la Haye, 1771. Goertz, Dissert, sistens novum ad ligaturam Polyporum Uteri instrumentum. 1783. Walther, De Polypis Uteri; in Ann. Academ. Berol., vol. i. p. 20. 1786. Nissen, Dissert, de Polypis Uteri, novoque ad eorum ligaturam instrumento. Gotting., 1789. Stark, Ueber Mutterpolypen und Umkehrung der Gebarmutter; in Stark's Neue Archiv. fur Geburtshiilfe, u. s. w., vol. i. part iii. Heinze, Dissert, de Ortu et Discrimine Polyporum, praecipue Polyporum Uteri. Len., 1790. Zeitmann, Dissert, de Signis et Curatione Polyporum Uteri. Jenae, 1790. SYMPTOMS OF POLYPS OF THE WOMB. 487 Rothbarta, Dissert, de Polypis Uteri. Erfurt, 1795. Segarf, Dissertation sur les Polypes Uterins. Paris, an xii. Lefaugheux, Sur les Tumeurs circonscrites et indolents duTissu cellulaire dela Matrice et du Vagin. Paris, 1802. Roux, Memoire sur les Polypes Uterins; in his Melanges de Chirurgie et de Physiologie. Hauk, Ueber Gebarmutter Polypen; in Rust's Magazin, vol. iii. p. 263. Mayer, De Polypis Uteri. Berol., 1821. Boivin et Duges, Traite pratique des Maladies de l'Uterus et de ses annexes, vol. i. p. 333. Paris, 183:3. Besides which many observations may be' collected from writers on nasal polyps. 2367. Polyps of the womb are formed either in its fundus, its body, or its neck. In general they resemble each other in having a long pear- shaped form with a thin neck, in being of a fleshy or fibrous structure, and in being covered with a smooth shining skin. Various differences are however observed, as they are sometimes round with a broad base, have an uneven, cleft surface, and their internal structure is sometimes more soft and spongy; at other times more tough, and sometimes having cavities which contain different kinds of substances. Sometimes they are very vascular, and at other times contain few vessels. Their size differs, and is sometimes very great. Mucous polyps are rarely pro- duced. I have seen a polyp, which though rooted in the cavity of the womb itself, hung out two inches below the fissura magna, in structure resembled a mucous polyp, and at its lower edge it had fringed lobes, and an aperture through which a thick probe might be passed to its root. Upon mucous polyps in the womb, in old women, accompanied with leucorrhoea, but without bleeding, (hypertrophic mucous sacs,) Nivet and Blatin (a) may be consulted. 2368. The symptoms characterizing a polyp of the womb are, at first, very doubtful; whilst small it causes no remarkable inconvenience to the womb. As it increases, it often excites squeamishriess, disposition to vomit, weight and dragging in the loins and region of the sacrum, shoot- ing and itching in the breasts. The walls of the womb are gradually distended by the polyp; its vaginal portion becomes shorter, thicker, and harder, and the lower portion of the womb is larger than usual. By the continued growth of the polyp, the mouth of the womb is at last opened, when an escape of bloody fluid, and often violent bleeding, takes place, and the polyp protrudes through the mouth, either gradually or suddenly, on every exertion, in jumping and falling, going to stool, and the like, with pains like labour pains, and dragging of the generative organs. If the polyp protrude into the vagina, it enlarges quickly, causes pressure on the bladder and rectum, and consequent difficulty in voiding the urine and stools; the pain in the lumbar and sacral regions becomes greater, and there is often considerable bleeding, occurring either of itself, or from any exertion, shaking of the body, or the like. These bleedings depend on the constriction which the polyp suffers from the mouth of the womb, in consequence of which the blood collects and the vessels burst. The discharged blood is sometimes very red, sometimes black, sometimes brownish or watery, mingled with flocks and fibres, and excessively stinking; sometimes whole pieces of clotted and very filthy-smelling blood are discharged. Sometimes no blood escapes, but (a) Archives Generales de M6decine, vol. iii. p. 195. 1838. 488 SYMPTOMS OF POLYPS OF THE WOMB. only a quantity of rawcMs-like serous fluid, which greatly weakens the patient. The growing polyp at last protrudes from the vagina, and ap- pears externally. By the weight of the polyp, the womb is constantly dragged and pulled down, and there is, consequently, a sensation of con- tinual dragging and tension in the belly; eversion of the womb may ensue, the discharge of urine be greatly interfered with, the belly blown up and painful, repeated bleedings, the general health considerably affected; the breathing becomes difficult, dry cough, loss of appetite and hectic fever may ensue, and death follows, either from continued pull upon the constitutional powers, or suddenly from bleeding. As the polyp protruding from the vaginais exposed to the air and to the contact of the urine, constant irritation is kept up on it, and hence often ulceration is produced. < 2369. If a polyp form on the neck, or in the neighbourhood of the mouth of the womb, it is noticed earlier, as it soon protrudes into the vagina, and does not distend the womb as when rooted in its fundus; it causes pressure on the bladder and rectum, and rarely bleedings, as it is not constricted by the mouth of the womb ; by its weight the womb is pulled and dragged down; the neck and mouth of the womb often so swells, that the bound between it and the polyp is completely lost. In consequence of the irritation of the womb kept up by the polyp, scirrhous or steatomatous degenerations may be produced. A polyp arising from the fundus of the womb, when sinking downwards, may be- come adherent to the wall of the vagina, and so have two roots; it may, therefore, when quickly protruding through the external generative organs, evert the womb and the vagina, in consequence of which, according to its seat on the latter, there may be produced a hollow in the rectum, where it corresponds with or on the^m- tonaeum, where it is attached to the vagina. If the protruded part of the vagina do not differ from the stem of the polyp, it may be tied with it in the operation (a). 2370. The symptoms produced by the development and further pro- gress of polyps, may give rise to their being mistaken for pregnancy, eversion, and prolapse of the womb, fungous growths, and scirrhous dege- nerations. 2371. As long as the polyp remains in the cavity of the womb it may be mistaken for pregnancy; the diagnosis, however, rests on the following circumstances. In pregnancy the vaginal portion of the womb is only gradually distended; it is elastic and feels soft, the mouth of the womb remains closed, and opens only during labour. With polyp the internal mouth of the womb opens without true pains, and remains oftentimes long open, without the vaginal portion being so regularly expanded, with- out being soft and thin, and without the lips of the womb-mouth so com- pletely disappearing. The mouth of the womb w7ith the polyp is harder, in pregnancy softer. The menstrual discharge is rarely suppressed with polyp, but irregular, more frequent, and not rarely painful; the blood is paler, watery, mingled with fibrous parts ; and there is, in addition to the discharge, a mucous ill-smelling fluid, like water in which flesh has been washed. In pregnancy menstruation occurs only in rare cases, but is regular, as concerns its coming on and character. The general symptoms occurring at the beginning of pregnancy diminish and entirely disappear (a) Berard, (These,) Observations relative aux Polypes de l'Uterus et a quelques-une» des Maladies des Organes Genito-TJrinaires. Paris. DIAGNOSIS AND CAUSES. 489 in its progress; but with polyp, on the contrary, they increase. The enlargement of the belly in pregnancy is greater and more regular; but with polyp is more unequal, does not attain the size of pregnancy, and depends on the growth of the polyp. The enlargement of the breasts is not so gradual with polyp of the womb as in pregnancy; they are some- times full, sometimes flabby, and never so large. To conclude, the continuance of pregnancy is definite, and, at a certain time, the move- ments of the child are perceptible. In mole-pregnancy, the distention of the belly and the alteration of the vaginal part of the womb, which shortens and softens, takes place more quickly; the mouth of the womb remains closed till the mole is protruded, which happens suddenly and not gradually; there, also, is not the discharge as with polyp. 2372. As to the mode of distinguishing a polyp which has protruded through the mouth of the womb from eversion of that organ, it must be observed that in incomplete eversion, the swelling passing through the mouth is broad above and narrow below ; hence also the mouth of the womb is always more open than with polyp, as that has a directly con- trary form, being broad below and narrow above. In eversion, which is not of long standing, the replacement of the womb is in general possible, in consequence of which the pains are lessened, whilst' after such attempts the polyp always protrudes again. The polyp is less sensitive than the everted womb. Eversion usually occurs after a very recent labour; the polyp is more moveable than the everted womb, its surface is smooth, and the bending in of the fundus of the womb may be felt through the walls of the belly, if the eversion be anywise great. Complete eversion resembles polyp in the form of the swelling, as it is narrow above and broad below, but it is surrounded by the mouth of the womb like a fold. With polyp the finger, or a probe, may be passed deeply between it and the vagina, but it cannot be by the side of the everted womb. The slem of a polyp is hard, the upper part of the everted womb is yielding, be- cause it is hollow. Eversion occurs after a birth. Notwithstanding these different signs, the distinction of polyp from everted womb, especially if partial and of long duration, is very diffi- cult, so that the most able practitioner cannot be certain without exami- ning by the touch. As, however, as has been already noticed, {par. 1287,) the form as well as the sensibility and mobility of the polyp varies ; both swellings may have a smooth or an irregular surface ; the polyp may appear soon after delivery; examination of the belly affords, in stout persons, no definite result, and with a polyp rooted at the fun- dus of the womb, the fundus may be, in its further protrusion, dragged down, and a certain degree of eversion produced (a). Careful obser- vation seems to prove the fact that a polyp, when it has once passed through the mouth of the womb, grows quickly. 2373. The mistaking a polyp which has descended into the, vagina for an imperfect prolapse of the womb is not very possible, as the polyp is softer and less sensitive than the protruded womb, has generally a bean-shaped form, without any opening at its lower part; and when at this part there is even a pit resembling the mouth of the womb, no probe can be introduced into it; replacement is impossible with a polyp, (a) Chelius ; in Heidelb. klin. Annal. Vol. iii.—42 490 TREATMENT OF POLYPS OF THE WOMB though it may be effected with prolapsed womb and the pain thereby relieved. If the finger or a probe be introduced between the polyp and the vagina, it may pass deeply, whilst, on the contrary, in prolapse it is soon stopped. In prolapse there is no repeated bleeding. In com- plete prolapse of the womb the distinction is still more easy. 2374. Fungous growths are distinguished from polyps of the womb in that they are the consequences of a scirrhous state of that organ, the mouth of which is hard, painful to the touch ; is even more or less irregularly shaped, and bleeds on the slightest touch. Scirrhous swell- ings of the mouth of the womb are characterized by the feel of gnaw- ing and burning, by stabbing, boring pain, which at first remits, but afterwards is continual; by a copious white discharge which corrodes the parts; by the discharge of pieces of black blood, by very great hardness of the swelling, irregularity, and pain when touched. 2375. The causes of polyps of the womb are in many cases un- known. Irritation of the womb, repeated difficult deliveries, frequent connexion, onanism, venereal discharges, and the like, may frequently produce them ; but more commonly they arise without any such previous ailment; and they have been noticed eyen in young girls. Most com- monly they occur about the period of the cessation of the menstrual discharge, when the altered vital condition of the womb favours unna- tural productions. They are very rarely seen in old women. 2376. The treatment alone consists in the removal of the polyp by operation. Only in rare cases has it been noticed that the constriction of the polyp by the mouth of the womb has caused its complete sepa- ration and cure. The result of the operation is the more favourable in proportion to the ease with which the stem of the polyp can be got at, and the less thick and firm it be. When there has been for a long time great loss of blood, other symptoms quickly arise after the operation which require particular treatment. So long as the polyp is still not large, it is covered with a membrane connecting it with the womb, and which tears as the polyp grows. Hence the reason why the operation on large polyps is commonly attended with slighter symptoms than the smaller: hence after the operation the recurrence of the disease is gene- rally less to be dreaded than after nasal polyps. When there are other organic changes of the womb, scirrhous harden- ing and the like, the prognosis is extremely unfavourable, as after the removal of the polyp it more quickly terminates fatally. Polyps of the womb do not hinder conception, but generally abortion takes place ; pregnancy, however, may reach its natural termination. 2377. Of the generally proposed methods for the removal of polyps, tying and cutting off are the most proper for those of the womb; pull- ing or twisting off, and destruction by escharotics, are inapplicable, partly oji account of the yielding nature of the parts in which the polyp is rooted, and partly on account of the condition of the space (1). The operation can only be undertaken in polyps of the womb when they have protruded through its mouth into the vagina. Before undertaking it a review must be taken of the cause of the disease, and of the patient's con- stitution. Hence a preparatory treatment is sometimes necessary; for instance, in syphilitic disease by using mercury; and in those persons BY TYING AND BY CUTTING INSTRUMENTS. 491 who have been very much weakened by bleeding, by strengthening remedies, and the like. > (I) Mayor (a) has vindicated twisting off. 2378. The number of instruments which have been proposed for tying polyps of the womb is very great; they may be arranged compre- hensively under the three following heads :— First. The ligature, which is carried round the root of the polyp by means of a double tube, or two separate tubes, or stems, connectable together, and tightened by means of these tubes. To these belong Levret's double cylinder (6), and forceps (c), with the modifications of , Keck {d), Laugier (e), Buttet (f), Contigli (g), and Clarke {h); also the instrument of David {i), Klett (j), Loeffler (k) Cullerier (I), Goertz (m), and Nissen (n); with the alterations, of Joerg (o), Meissner {p), and Gooch {q). Second. The loop is applied with the assistance of a loop-drawer around the polyp, and its tying managed with a single tube, or with a loop-tier. Here belong the apparatus of Herbiniaux (r), Stark {s), Desault {t), with Bichat's modification {u), John Hunter {v), and Ricou {w). Third. The loop applied around the root of the polyp, with a loop- drawer, and tied together by the use of little rings, through which the two ends of the ligature are passed. Such are the rosecrown instrument of Boucher (x), Loeffler's alteration (y), Sauter's {z) combination of it with Ribke's instrument {aa). * 2379. Of these several instruments for tying polypsof the womb those only will be here mentioned, as being most suitable, which were em- ployed by Desault, and the tier of Nissen and Ribke. Previous to the operation the rectum must be emptied With a clyster. The patient is to (a) Note sur l'Extirpition des Polypes Weibes, fig. iii.-vii. Lipz. 1821. Second uterins par torsion ; in Gazette Medicale de Edition. Paris, vol. xii. p. 529. 1844. (p) Above cited, fig. i.-vi. (6) Mem. de l'Acad. de Chirurg., above (q) An Account of the most important cited, pi. xiii. Diseases peculiar to Women. London, 1829. (c) Journal de Medecine, vol. xxxii. p. (r) Above cited, pi. i.—iii. 531, fig. I—6. 1770. (s) Stark's Archiv.C. I., p.I52, figs, i.-iv. (d) Ibid., vol. xxix. p. 529. . (i) Above cited, pi. iv.—HASsELBERG,Com- (e) Journal de Medecine, vol. xxxiii. p. merit, chirurg. in qua novum humeri ex 363. 1770; vol. xxxv. p. 173. 1771. articulo exstirpandi methodum, novumque (/) Ibid., p. 66. ad ligaturam Polyp >rum instrumentum pro- (g) Raccolta di Opu-cuolo Medico-practi- ponit. Gryph., 1788. ci, vol. iii p. 139. {u) Memoires de la Saciete d'Emulation, (h) Observations on those Diseases^of Fe- an n. p. 33.* males which are attended by Discharge. (v) In B. Bell, above cited. London, 1814; with ten plates. (10) Ms moire et Observations sur les (i) Loder's Chirurgische Bemerkungen, Polypes Uterins, avec un nouvel instrument vol. i. pi. ii. fi,r. 4 and 5. pour en faire la Ligature; in Museum der (j) Stark's Archiv. fur die Geburt- Heilkunde von der helveti^chen <*esellschaft shulte, vol. iii. p. 548, fig. i. iii. a. c. cprrespondirender Aerzte und Wundaertze, Ik) Ibid., vol. iv. p. 301 vol. ii. pi. v. Zurich, 1794. (l) In Lecfaucheux, above cited.—Hufe- (x) Beinstein; in Loder's Journal, vol. ii. land and Aarless, Noues Journal, vol. ii. p. 626, pi. x. p. 196, pi. 2. (y) Hufeland's Journal. 1813; part iv. (m) Above cited, fig. 1,2. p. 65. (n) Above cited. (z) von Siebold's Chiron, vol. ii. p. 420, pi. to) Handbuch der Krankheiten des vii. figs. 1-8. (aa) Rust's Magazin, vol. iii. p. 153, 492 TREATMENT OF POLYPS OF THE WOMB be placed on a bed or table, so as to be in a half lying, half sitting pos-r ture, and the perineum and region of the coccyx exposed. The thighs must be separated by an assistant, and a careful examination made to ascertain the nature and seat of the polyp. 2380. Desault's apparatus is to be employed as above mentioned {par. 2337.) A pretty strong ligature must be passed through the eye of a loop-drawer, and to a silver tube somewhat curved forwards, and the end of the ligature fastened on one ring of the silver tube. This and the loop-tier are now carried parallel to each other between the swelling and the wall of the womb on that side where there is least resistance, and by slightly moving it laterally, carried to the upper part of the stem of the polyp. That end of the ligature attached to the ring of the tube being loosened, the loop^drawer is held fixed with the left hand, whilst with the right the tube is carried round the whole swelling and back to the loop-drawer. The hands are now to be used instead of the instruments, and so crossed over each other that the part of the loop which the tube draws with it may pass over that held by the loop-drawer. The tube is now drawn back, whilst the drawer is kept steady, the two ends of the thread passed into the opening of a loop-tier, and this pushed up to the root of the polyp, whilst the ends of the. thread are held fast, the stem of the loop-draw'er is then pressed forwards, the ligature removed from its aperture, and the drawer removed. The twro ends of the ligature are now drawn sufficiently tight, and fastened to the notch of the loop-tier. This mode of treatment is very worthy of recommendation on account of its ease and certainty, The objecUop that the ends of the ligature, not being contained in a* tube, may be softened and loosened by the continual moisture, is, according to my experience, groundless. If it be desirable to measure each time the degree of tightening, that may be easily done by means of a stop-wheel placed at the .end of the loop-tier. 2381. Nissen's polyp-tier is used in the following manner:—The instrument well oiled, and having a thread unlooped attached to it, is passed with the forefinger of the left hand up to the root of the polyp. The handle by which the two tubes are connected is now removed, and one tube being held steadily, the other, w7ith its concavity towards the polyp, is carried round it to its fellow, and the two are then connected by slipping on and pushing forwards the rings, and attachingthe handle. The ligature is how drawn closely together and fastened ; or it is tightened with the screw as recommended by Joerg. 2382. In using Ribke's instrument, the two loop-drawers are intro- duced, like the single blades of delivery-forceps, up to the root of the polyp, the stem which holds the two cylinders together is drawn out, and then each of the latter is carried round in a half circle till they meet again, and are then fastened together with the stem. The assistant, who has hitherto held the stop-wheel, now presses the knobs to the upper end of the connected cylinders, after which the stilettes in the latter are drawn go far out at the lower opening that the loop is set free, and the cylinders can be withdrawn- The root of the polyp is now tied and properly fastened by the stop-wheel, which is laid on a pad upon the mons Veneris, and confined there by a broad cloth around the loins. 2383. The symptoms which may occur after the tie has been made are, violent inflammation and fever, pain, spasm, bleedings, and other symp- BY CUTTING. 493 toms from pressure of the swelling polyp. In the first case suitable anti- phlogistic treatment must be employed; in spasm, narcotic remedies used, and if the symptoms be not diniinished by these, the loop must be slackened a little; the bleeding must be stopped by more tightly tying the ligature, and with astringent injections. On account of the increasing bulk of the polyp it is generally necessary for the first few days to empty the bladder with the catheter, and the rectum by clysters. 2384. The patient must after the operation keep perfectly quiet in bed; and have a proper diet. Every two days the ligature must be tightened ; and to prevent the effect of the stinking ichor, repeated injections of decoctions of aromatic herbs must be employed.. When the polyp has dropped off, which depends on the thickness and toughness of its root, and occurs at different periods, either by the continued tightening of the ligature, or on some movement of the patient, the injections must-be con- tinued for some time. Strengthening remedies must also be given to support the patient's diminished powers. When the polyp, after having separated, is still retained, in conse- quence of its size, it must be withdrawn with forceps, for which purpose deli very-forceps and much force are often requisite ; as happened to me in one case. If bleeding occur on the dropping off the polyp, astringent injections must be used, which are not, however, to be very irritating, or great irritation of the womb will ensue. If, notwithstanding the repeated tightening of the ligature, the polyp will not separate, which, however, is very rarely the case, it is advisable, to save the patient the incon- venience of the continued stench, to cut it off below the ligature. In large, long-continued and far extending polyps, it is possible that the fundus of the womb may be dragged down, the ligature must therefore not be tied too high up. 1 have related a fatal case of this kind (a). 2385. Cutting off polyps of the womb, the oldest method, is, on account of the danger following, and the difficulty of stanching the blood, only to be employed in particular cases, for instance '.first, when the polyp, after having been tied fast during several days, has not dropped off, in which case, generally, considerable pain follows every tightening of the liga- ture ; second, when the polyp hangs down, or can easily be drawn out, if its neck can be got at, is thin, and there have been no previous bleeding; third, when the polyp has produced eversion of the womb, accompanied with dangerous symptoms, which can only be got rid of by the quick removal of the polyp. Siebold (o), however, not only in this, but in all other cases, prefers cutting off to tying a polyp cff the womb, when it has a neck and can be reached, whether it be. at the fundus, in the body, or at the neck of that organ. If in consequence of the breadth of the base by which it is attached to the fundus or body of the womb, cutting off' the polyp be not possible, he ties it, for the purpose of contracting the stem, and then cuts it off'below the ligature. This mode of proceeding is less painful, more speedy, unattended with any particular symptoms, without fear of bleeding, and even should that happen, it is easily stanched (a) Heidelb. klin. Annalen, above cited. tomique des Polypes de la Matrice, sur (b) Ilandbuch zur Erkenntniss und Heil- Temploi de la Ligature et sur les avantages ung der Frauenzimmerkrankheiten, vol. i. p. de la resection de ces tumeurs ; in Journal 710. Second Edition. 1821.—Hervez de General de Medecine. 1827; vol. ci. p. 1. Chegoion, Remarques sur la disposition ana- 42* 494 TREATMENT OF POLYPS OF THE WOMB BY CUTTING. by plugging; the patient is not inconvenienced by a hateful smell and discharge, may leave her bed in a few days, and has little fear of a relapse. Dupuytren's repeated operations in this way entirely confirm Siebold's statements (Pigne); and although practice shows that the result after cutting off the polyp may be fatal (a), so on the other hand it shows that after tying, there may be severe, and even fatal bleeding (b). 2386. Cutting off a polyp of the womb is to be performed in the fol- lowing manner:—The patient being placed in the same position as for the operation for the stone, an assistant presses on the belly to force down the womb, whilst another keeps the labia asunder. The polyp being found in the vagina, a speculum with moveable branches is introduced, and the walls of that passage are expanded with it, so as to isolate the polyp, which is then seized with Museux's forceps and the speculum withdrawn. Whilst the polyp is gradually drawn down, another pair of Museux's forceps are to be applied higher up and at another diameter, and the drawing down is to be continued, whilst the patient holds her breath and forces, till the neck of the womb and stem of the polyp are seen, when it is to be cut off'with scissors or with a kinfo. The accompanying pain is only very little, there escape only a few drops or a teaspoonful of blood, the womb rises again, and a few days are sufficient for the cure. When the neck of the polyp is still engulfed in the womb, the neck of the latter must be cut into to reach the stem of the polyp (Dupuytren.) If the polyp protrude at the external generative parts, it is only taken hold of with the fingers or forceps and drawn a little out. The scissors for the performance of this operation should be curved on their flat surface, have their end rounded, and be provided with long handles (Siebold) (c). The previous application of a ligature around the neck of the polyp, after drawing it down, and before cutting it off, which is recommended by some practitioners, Dupuytren and others consider unnecessary. If there be bleeding, cold injections should be thrown up, cold applications made to the belly, and plugs of lint, strewed with or steeped in astrin- gents, introduced. , 2387. Polyps of the vagina, as regards the symptoms they produce, and the treatment they require, are of less consequence than those of the womb. They are soon discovered by examination, and only when very large, cause pressure on the bladder and rectum. Their causes are in- flammation, and.injury of the vagina, venereal poison, and the like. Their removal is either effected by tying, which is little difficult, and often done merely with'the hand, or by cutting off; and the same rules are to be followed as in the operation for polyps of the womb. [Occasionally a vaginal polyp will, from s*ome accidental cause, separate of its own accord, without any surgical aid; an instance of this kind occurred to me a few years since.^-^. f. s..] (a) Mayer, above cited. chern des fistr. Staates. Neuste Folge, vol. (b) Amming, Einige praktische Bemerk- vii. part ii. p. 285. ungen ueber die Gebarmutterpolypen und (c) Mayer, above citedt figs. i. ii. iii. ihre Entfernungsarten; in Med. Jahrbii- OF CANCER. 495 F.—OF POLYPS OF THE RECTUM. Desault, above cited, vol. ii. p. 498. 2388. Polyps of the rectum are situated either near the verge of the anus, and are then external, or they are deeper seated, and can only be protruded in going to stool, or even remain concealed in the gut. They are generally round, not large, necked, and of a pale-red colour. Some- times there is only one, but at other times several. 2389. Those polyps which constantly lie out of the rectum, may be grasped with forceps, drawn^down, and taken off at their root with a stroke of the bistoury, or with the scissors; and this applies also to such as are situated higher, but can be forced out. If, however, the polyp be seated so high, that it will not be forced out of the rectum, the ligature is the only remedy, and is best applied according to Desault's method. XVII.—QF CANCER. (Cancer, Carcinoma, Lat.; Krebs, Germ.) Peyrilhe, Dissert, de Cancro. Paris, 1774. Le Dran, Memoire avec un Precis de plusieurs Observations sur le Cancer; Mem. de l'Acad. de Chir., vol. iii. p.'l. Jaenisch, Vom Krebse und dessen Heilart. Petersburg, 1793. Pearson, John, Practical Observations on Cancerous Complaints. London, 1793. 8vo. Whistling, Aeltere und neuere Kurmethoden des offenen Krebses. Altemb., 1796. Legaux, Dissert, sur le Cancer. Paris, an xi. Roux, P. S., Memoire sur le Cancer; in his Melanges de Chirurgie et Physo- logie, p. 149. Paris, 1809. 8vo. Home, Everard, Observations on Cancer connected with Histories of the Dis- ease. London, 1805. 8vo. Ferrier, Dissert. Observations et Considerations sur le Cancer. Paris, 1806. Bayle, Vues theoretiques et pratiques sur le Cancer; in Biblioth^que Medicale, vol. xxxv. Paris, 1812. Wenzel, C, Ueber die Induration und das Geschwiir in indurirten Theilen. Mainz, 1815. Abernethy, John, A Classification of Tumours; in his Surgical Works, vol. ii. p. 68. Edition of 1815. Bayle et Cayal, 'Article Cancer; in Diet, des Seiences Medicales, vol. iii. p. 537. 1 Scarpa, Antonio, Sullo Scirrho e sul Cancro. Milano, 1821; and Opuscuoli di Chirurgia, vol. i. Pavia, 1825. von Walther, Ueber Verhaxtung, Scirrhus, harten und weichen Krebs, Medul- larsarkom, Blutschwamm, Teleangiecktasie, und Aneurysma per anastomosin; in his Journal fur Chirurgie und Augenheilkunde, vol. v. p. 194, p. 567. Recamier, J. C. A., Recherches sur le Traitement du Cancer. Paris, 1829. 2 vols. 8vo. Cruvelhier, Anatomie Pathologique, livr. iv. and viii. Paris, 1829. Muller, Johan, above cited, p. 10. Canquoin, Traitement du Cancer. Paris, 1836. 8vo. Carmichael, Richard, M. D., An Essay on the Effects of Carbonate of Iron upon Cancer; with an Inquiry into the Nature of that Disease. London, 1806. 8vo. Travers, Benjamin, Observations on the Local Diseases termed Malignant; in Med.-Chir. Trans., vol. xv. 1829. Hodgkin, Thomas, M. D., On the Anatomical Character of some Adventitious Growths; in Med.-Chir. Trans., vol. xv. 1829. 496 ORIGIN AND SYMPTOMS OF CANCER. 2390. That degeneration is called Cancer which is the consequence of ulceration of a Scirrhus, has a decided disposition to destroy all parts without distinction of their nature, which never heals, and which having arrived at a certain height, produces peculiar general disturbance. 2391. Two distinctions are established in reference to the origin of cancer; it is either developed from a previously formed scirrhus, or it arises from some other swelling, or some other ulcer in which the scir- rhous degeneration has been set up. 2392. In the first case different periods may be distinguished in the development of the cancer. There arises generally without any known case, sometimes in consequence of external violence, a defined tumour, or a swelling of some one organ which is generally quite free from pain, though rarely very sensitive; from the first it is very hard, irregularly knobby, and heavy, though sometimes regularly elastic on the surface, and soft at some parts. The skin covering the tumour is in its natural state; the substance of the organ in which it is formed, is usually in- creased ; though sometimes it crumples together, and is then firmer. These symptoms designate the first stage of cancer {Scirrhus). The con- tinuance of this stage is indefinite, though mostly long, and especially the harder the swelling, the older the individual, the less vascular the organ', and the more all dynamic and mechanical -irritation be wanting, and the secretions and excretions remain natural. The general health is commonly undisturbed during this period, and the countenance un- changed ; sometimes, however, various derangements, loss of power, wasting, earthy countenance, irregular febrile action arid the like appear, by which a more speedy progress of the disease is indicated. 2393. Of its own accord, or in consequence of some evil influence upon the swelling it becomes irritable; the patient feels shooting, and excessively painful stabbings, or has the feel of constant burning in the tumour. The hardness and the extent of the hardness constantly in- crease, it becomes more knotty and knobby; the skin covering it is bluish-red, tense, adhering to the surface of the. swelling, and the veins upon it swell (Concealed cancer, Cancer occultus, Lat.; verborgener Krebs, Germ.). The neighbouring lymphatic vessels and glands swell, become hard and painful, the constitution is more or less disturbed, loss of appe- tite follows, indigestion, wasting, and cachectic earthy countenance. 2394. Under aggravation of the above symptoms the thinned skin at last breaks, and an ichorous, bloody, brownish, or limpid fluid escapes, without the bulk of the tumour being in the least diminished; an ulcer is formed with hard edges and with irregular surface ; very painful fungous growths spring up; an excessively stinking ichor is discharged; the neighbouring glands, even those lying beyond the course of the lymph, swell, and all parts are destroyed by the ulcer spreading in every direc- tion after they have first assumed a scirrhous state. Bleedings frequently come on, the body wastes considerably, the skin assumes a peculiar yel- lowish-gray colour, the countenance has the characteristic impress of deep-seated disease; collections of serum are formed in the cellular tissue, and in the cavities; peculiar frangibility of the bones; hectic fever with nightly sweats, and colliquative diarrhozay and the powers of the patient are exhausted. SYMPTOMS AND KINDS OF CANCER. 497 2395. If a scirrhus be examined before any ulceration have taken place, there is found a hard, firm, incompressible substance which, cut into thin layers, is semitransparent, has the consistence of cartilage and fibro-carti- lage to that of lard, with which appearances it in general agrees, and is composed of two different substances ; the one hard and fibrous, the other soft and seemingly inorganized. The fibrous part forms without regu- larity various partitions and cavities, in which is contained a soft sub- stance, having usually a pale brownish, sometimes bluish, greenish, whitish, or reddish colour, similar to hardened albumen. The fibrous part has sometimes a cartilaginous hardness. But specially are the pro- portions of these two substances very different; sometimes the fibrous substance forms as it were the nucleus, from which the partitions spread in every direction, and on the substance being cut, a radiated appearance is presented. Sometimes the whole swelling forms an homogeneous hard lard-like substance, in which no definite tissue can be discovered. Between these two extremes there are various links, merely distinguished by the different proportions of the two substances. Sometimes encysted tumours filled with fluids of different colours are found in a scirrhus. The scirrhus specially exists either as a tissue different from the organ in which it is developed, or from the conversion of the substance of the organ itself; in the latter case, the boundary between health and disease cannot be accurately determined. If the tumour be examined in the state of concealed cancer, the lard- like substance is found harder in the centre than at the circumference; here and there it is spotted with red ; rough and uneven at some parts, with cells of different size which are filled with a viscid, ash-gray, bloody fluid, of a very acrid nature. The edges of these cells which are found in the interspaces of the fibrous streaks are pale-red, and their inner walls covered with a soft and fungous substance; from which last may be here and there separated, by scratching with the finger-nail, little portions of the hard-white matter lying beneath (a). Microscopic examination presents the following as elements of scirrhus. First, cells of very great variety in different cases; simple cell-nuclei with nuclear corpuscles, sometimes surrounded with very pale cells, some- times with completely formed cells, in general rounded, sometimes studded with granules, or having granular contents. Tailed cells are rare, and when existing, seem rather dependent on the development of the fibres. Sometimes there are very characteristic cells, with very thick double walls and granular contents. Granules and fat-corpuscles are frequently mixed together with the cells, sometimes singly, sometimes collected in heaps, and sometimes as it appears enclosed in cells. Second, fibres, sometimes broad and band-like, sometimes narrow, and not unfrequently elastic fibres. The arrangement of the fibres varies considerably. Third, together with the cells and fibres there is commonly found as an actual element of scirrhus, a mucous fluid, which coagulates with acetic acid and solution of alum. Muller (b) distinguishes four several kinds of Carcinoma, according to the different nature of the tissue. First, Carcinoma simplex; second, Carcinoma reticu- (a) Scarpa, above cited, p. 29. (b) Above cited, p. 11. 498 MULLER AND HODGKIN'S fare; third, Carcinoma alveolare ,• and, fourth, Carcinoma fasciculatum. Therewith he also reckons Carcinoma medullare and melanodes. In Carcinoma simplex and fibrosum, the uneven, generally lobeless substance which resists the knife, presents when cut through, a gray basal mass, which seems only remotely similar to cartilage, and in which there are irregular whitish bands. Scirrhus of the breast sometimes exhibits here and there white threads, in which a space can be perceived, and in it some colourless, whitish, or yellowish contents. It seems to originate in the thickening of the walls of the milk canals and lymphatic vessels. In scirrhus of nonglandular organs, no such hollow white threads are observed. The substance consists of a fibrous and of a granular gray substance. The former rarely appears distinct when cut through, but is seen on scraping off the gray matter, for which it is also the bed and presents a very irregular mesh-like tissue of bundles of tough fibres. The gray substance is composed entirely of microscopic formative corpuscles, which have little connexion with each other, are transparent and hollow cells or vesicles, with a diameter of from 0,00045-0,00120 of a Paris inch in diameter, and are soluble in neither cold nor boiling water nor acetic acid. In many of these cells may be distinguished merely some small spots, having the appearance of little granules; in others, a large corpuscle, like a nucleus, or little vesicle contained in the cell-corpuscle. Besides the formative corpuscles, many little knobs of fat are always found scattered in the scirrhous substance. Carcinoma reticulare when cut through is distinguished from Carcinoma simplex by the white reticulated figures distinguishable with the naked eye, which run through the gray substance, and by its tendency to form lobes as well also as by the greater bulk which it acquires. In consistence it sometimes resembles scirrhus, sometimes is softer and approaches medullary fungus; hut with this variety of consistence the structure always remains the same. It is composed of a gray globular basal sub- stance, embedded in a mesh-like tissue of bundles of fibres, first observed by scraping, or by getting rid of the gray granular substance by maceration. The latter consists of similar transparent formative corpuscles or cell-corpuscles to those of Carcinoma simplex, which contain one, two, or several little vesicles with pale nuclei. In other cases, the little nuclear cells cannot be distinguished within the large formative corpuscles; on the contrary, many little granules are seen in the interior of the transparent cell-corpuscles, and such also are sometimes observed in large quantities lpose between the vesicles, the smallest exhibiting molecular move- ment. Characteristic are the white or yellowish-white reticulated figures, more or less distinct but never deficient, which have no expanded little- vessels with thickened walls, but are peculiar formations, and consisting of a deposition of white granules in the gray substance. They do not appear to be cellular, but seem for the most part a, conglomeration of opaque granules of roundish and oblong corpuscles, which are two, three, or four times as large as the blood corpuscles. These white corpuscles collect more and more during the progress of development, and form an element of the self-destroying tissue, sometimes whole pieces which are enclosed by the other substance or line, the interior of the existing cells from whence they detach themselves like a film. The corpuscles thence pass into the softening and suppuration of the broken up surface. With further development the reticulated figures readily flow into irregular white spots; their appearance then has some resemblance to the first appearance of white tubercles in the gray basal substance. Carcinoma alveolare exhibits an irregular knobby surface, and as the base of the substance, a tissue of endless, crossing, very firm, white fibres and plates, between which simple cells are found, from the size of grains of sand to that of the largest peas, which are closed, but frequently communicate with the neighbouring cells, and all contain a very viscid pale, very transparent jelly. Under the microscope the little cells are seen to enclose still smaller cells, and these again contain still less. On the little cells the dusky-yellowish nucleus of its wall is plainly seen. Many cells also contain simple nuclei loose in their interior. The large cells are distinctly fibrous in their walls, and the fibres pass from one cell to another. Carcinoma fasciculatum is distinguished by its throughout fibrous structure, which may be seen either by breaking or cutting through it. The tumour may be easily torn in the direction of the fibres, is not thereby crumbled, and under the microscope shows neither the cell globules of other carcinomata, nor the tailed bodies of the seemingly fibrous medullary fungus. The arrangement of the fibres is either tuft- DEVELOPMENT AND PROGRESS OF CANCER. 499 like, and then the fibres can be torn into simple radical bundles, of which the points are directed towards the bottom and their base towards-the irregular surface, or the bundles form different sets of fibrous expansions. Whole masses of fibres form one tuft, others different tufts. The large bundles of fibre's thrust through each other, as is seen on tearing them asunder. In this case the swelling readily forms large and Small lobes upon the surface and even in the interior. Between the lobes mem- branous partitions pass, to which the tufts of the fibrous substance are attached. Sometimes it is seen how the fibrous substance arises on a membranous surface, protrudes like a sheaf, then forms an arch above and again attaches itself to another membranous wall. These lobular throughout fibrous tumours often acquire con- siderable size. But the lobular form may be entirely wanting, and the whole swelling consist of a single tuft of radically arranged fibres. These swellings are very vascular, and the vessels have a straight course similar to the fibres. The substance of the swelling is sometimes transparent like jelly. The fibres are throughout pale and transparent; their surface is here and there beset as if tinctured with nuclei. [Dr. Hohgkin (a) considers scirrhous to originate, like other malignant growths, from cysts, either of a simple or compound character, and has given the following excellent account of their development and progress:— "Scirrhous tumours have a more or less rounded form. On making the section of them they present various appearances, but are all more or less divided by septa, which affect sometimes a radiated form, and at others a cellular character. Both of these characters have been insisted on by many writers on this subject; but I believe the differences which have been observed in many instances depend on the direction in which the sections were made. * * * If we carefully dissect down to the surface of one of these tumours, we shall usually find that it has a capsule or covering, which has, I believe, generally been supposed to consist of the altered and con- densed cellular membrane of the parts which have given way before the growth of the tumour. This idea is probably correct with respect to the unequally thick external part of the capsule; but if we dissect carefully, and examine those tumours in which the progress of decay has either not commenced, or has made very little progress, we shall find that surface which is next to the mass of the tumour more or less smooth and even, and on raising it we find that it is reflected over one or more pyriform bodies, attached by a base, which is generally narrow or peduncular, to some part of the circumference of the enclosing capsule. Unless the tumour is very small, it is much more common to find several rather than a single body of this kind, and as there is often little, if any, fluid intervening between them and the enclosing capsule, their form is somewhat modified by their mutual pressure. Sometimes, though more or less closely applied to each other, these pedunculated bodies are perfectly detached at their sides, and may, consequently, be readily traced to the point which forms the common origin of their peduncles. At other times these bodies are so adherent amongst themselves, and the membrane covering them is so tender and delicate, that without very great care the arrangement of their structure may be overlooked, in consequence of the pedunculated bodies being broken or torn through in a different direction from that to which their mode of formation would naturally dispose them. It must be sufficiently obvious that the appearance presented by the section of a tumour, such as 1 have just described, must be very materially affected by the direction in which the section is made. If it pass through or near to the point at which the pyriform bodies are attached to the enclosing cyst, it must nearly correspond with the direction which some of these bodies take towards the circumference, and these edges will consequently be seen in the form of radiating lines. On the other hand, if the section be made more or less nearly transversely to the axes of these bodies, their section will convey the idea of cells of various shapes. If we continue dissecting and raising the outer cyst, for mi no- the reflected membrane which covers the radiating pedunculated bodies, we shall generally find that on one or more sides it dips down deeply into the mass of the tumour, and forms a part of the septum which separates the one packet of pe- dunculated bodies from the others, which generally concur to form the mass of the tumour; for it comparatively rarely happens that the tumour is composed of a single cyst filled with pedunculated bodies. On examining the different encysted packets (a) Above cited. 500 DEVELOPMENT AND PROGRESS OF CANCER. of pedunculated bodies which compose the tumour, we shall often find some indica- tion of their having taken their origin from nearly the same spot, which is generally the most indurated part of the tumour. We may likewise observe that the different secondary tumours, or encysted bundles of pedunculated bodies, are in very different stages of progress. In those in which the internal growth is most active, we shall find that a process has taken place perfectly similar to that which I described as occurring in ovarian tumours when the development of the contained cysts pro- duced the hernia or rupture of the containing one. The secondary cyst or cysts, which make their way through the containing one, rapidly advance when they are free from the restraint which its pressure afforded, and thus constitute another tumour, which adds to the original mass. If we examine the structure of this new tumour, we shall find that the subordinate growths of which it is composed, radiate from the point at which this tumour made its escape from the original one. At the same time that the escaped cyst or cysts acquire their more rapid growth, they often acquire a new character with respect to their consistence, which is generally much more soft and tender. * * * Those parts of the tumours in which the rapid and unrestrained growth is most remarkable, are generally situated near the circum- ference, where they are at once both exempt from the restraint of mutual pressure, and receive more abundant supply of nourishment from the surrounding natural structures. A marked difference exists between those just described, and others in which development has been restrained, or vitality lost by pressure, and consequent defective supply of nutrient matter. I have already explained the mode in which these effects are brought about in those ovarian tumours in which the secondary cysts are thickly crowrded and attached by very narrow peduncles. Precisely the same process takes place in the tumours of which I am now speaking; and when we make a section through one of them, which happens to be composed of many secondary tumours, and which consequently presents many centres of radiation, we shall often find that the pedunculated bodies connnected with one or more of these centres have lost their vitality by a natural strangulation or ligature, and also that the immediately adjoining parts which yet retain their vitality, irritated by that which has now acquired the character of a foreign body, are brought into a state of inflammation. The result of this compound action is the formation of a cavity filled Avith broken down and softened matter of a peculiar character, intermediate between suppuration and gangrene. This process very frequently takes place before the exterior of the tumours exhibits any symptom of irritation or inflammation, and to my mind, very satisfactorily accounts for that disposition to central softening and decay, on which Laennec, Wardrop, and some others, have so forcibly insisted as characterizing the progress of heterologue deposits. At the same time, I think I am correct in stating, that for the production of this form of gangrene or softening, the supply of nourishment should be pretty promptly cut off by the operation of the natural ligature. When the process proceeds more slowly, the parts which are under its influence gradually acquire an increasingly dense structure, and ultimately becoming penetrated by earthy matter, are allowed to remain unproductive of serious irritation, notwithstanding their deteriorated organization and diminished supply of nourishment. * * * Such tumours in the course of their development produce, by the irritation which they excite, a greater or less degree of thickening of the surrounding cellular structure, and sooner or later become visible externally, dilating the integuments which are stretched over them. The points at which this disten- tion is the most considerable are inflamed, the inflammation proceeds to ulceration, arid the tumour either sprouts luxuriantly at the part from which the pressure is thus removed, or participates in the ulcerative process. ^ "The ulcer is universally described as presenting elevated and everted edges, while, its ragged and depressed central portion is bathed by an unhealthy secretion, to which the name of pus can scarcely be applied. The mechanism by which this peculiar ulcer is produced, is well worthy of attention. I have shown that at the external part of the tumour its growth is most luxuriant, both from the want of pres- sure, and from the increased supply of nourishment. This will explain why the circumference of the tumour is the most elevated. The central parts, on the other hand, have not only to encounter the pressure which they sustain from the surround- ing parts of the tumour, and to suffer the diminished supply of nourishment which this pressure occasions, but moreover, ulceration having removed the integuments, all supply of nourishment from the surrounding natural structures is necessarily cut SECONDARY DEVELOPMENT OF CANCER. 501 off. The depth and irregularity of the central part of the ulcer is often further pro- moted by a communication being formed between this part of the ulcer and a cavity commenced and produced on the interior of the tumour by the process heretofore described." (p. 294-302.) "True scirrhous tumours," Hodgkin further remarks, "appear sometimes to de- pend on a single primary tumour; at other times, several may be satisfactorily made out. That part of the tumour which appears to have been the common origin of the primary cysts, where there are more than one, or from which the contained pedun- culated bodies radiate, when there is only a single primary tumour, is, in general, the most indurated portion, and is, at the same time, the most indistinct in its struc- ture. When examined externally, after the surrounding natural structures have been carefully dissected off, this part of the tumour is found to be the most irregular, has a somewhat corrugated appearance, and suggests the idea of its having been the sort of root by which the adventitious growth was implanted on the natural struc- tures. The radiated appearance so strongly insisted on by most authors who have described scirrhous tumours, and the rationale of which I trust I have shown, is particularly conspicuous when the section passes through this point. The fluid part of a true scirrhous tumour bears in general a very small proportion to the rest of the structure, it has a viscous or mucous character, more especially where softening has not taken place; but where this is going on it assumes the character of an offen- sive ichorous discharge, and acrid and highly deleterious qualities have by some been ascribed to it. The process of softening sometimes commences internally at one point, at other times in several small isolated points; in others, again, the ulceration through the integuments is the first part of the process of decay." (p. 323-25.)] 2396. The secondary development of cancerous ulceration may occur from venereal, herpetic, scrofulous, and other sores, as well also as from different kinds of growths, condylomata, warts, and polyps, wdiich are not originally carcinomatous, but by irritating treatment and the like, pass into a scirrhous condition. 2397. Cancer does not appear to be primarily developed in all tissues; at least, the muscles of locomotion, the serous membranes, cartilage, and tendon, are not originally attacked by it. The skin, the cellular tissue, the secerning and lymphatic glands, the mucous membranes ; the nerves and bones appear to be the only tissues capable of an original develop- ment of cancer. This disease also arises more frequently in some organs than others; it is most commonly seen in the gland of the breast, in the testicle, on the womb, on the lips, the tongue, the eye, on the penis, the cli- toris, and the like. The spreading of the disease to the neighbouring parts appears also proportional to their nature; the cellular tissue and skin coveringthe tumour are first attacked and destroyed, even before the tu- mour adheres to the underlying muscles, as for instances, in cancer of the breast. The serous membranes only become attacked at a later period. The bones for a long while withstand the destruction ; however, they are eaten into and at last destroyed, as well, indeed, as the vessels which are attacked latest, though, however, yielding to destruction, as the often occurring bleeding prove. When the disease has been still longer pro- tracted, the lymphatic glands which are in relation to the original scirrhus become affected ; sometimes this happens even at the onset, sometimes only in the latter stage of the disease. Walther (a) has disproved by cases, Scarpa's assertion, that true scirrhus never occurs primarily in a lymphatic gland. 2398. The symptoms which cancer presents in its origin and course (a) Above cited, p. 202, Vol. hi.—43 602 DIAGNOSIS AND PROGNOSIS OF SCIRRHOUS TUMOURS. are very different, and seem to depend on the difference of constitution, of the mischief producing it, and of the tissue attacked by it, as has been already noticed in the special consideration of the subject, although a definite causal relation in this respect cannot always be determined. Cancer is often excessively destructive, and eating, surrounded with hard edges, and sometimes accompanied with fungous growths. The former kind seems to be peculiar rather to old persons, to sanguineous and choleric temperaments; whilst the latter occurs in young persons and phlegmatic constitutions. Sometimes the 'course of the cancer is extremely quick, a large strip of the skin is suddenly destroyed, and the greater part of the cancerous swelling bursts through the turning out of the edges of the skin. In other cases the course of the cancer is tedious, the ulceration seems determined after the bursting of the swelling; the edges of the skin turn inwards, the discharge of ichor is slight, and the dis- ease may have long existed before it spreads. The mischievous influence of cancer upon the constitution also varies according to its seat in differ- ent organs. The general symptoms of cancerous dyscrasy often set in early, before softening and ulceration ; often it appears when there has been already farspreading destruction of the scirrhous part. Alibert (a) has laid down six different kinds of cancer; first, Cancerfungoides, common cancer; second, Cancer terebrans, cancer of the skin ; third, Cancer eburneus, hard like ivory; fourth, Cancer globosus, presenting a roundish swelling, usually painless, of a violet or blackish colour, and generally, not confined to one spot, but affecting large streaks on the head, feet, and so on; fifth, Cancer anthracinus, arising with a black spot in the skin, accompanied with a painful itching, and, as it enlarges, a mulberry-like excrescence rises out of it; sixth, Cancer melaeneus, tuberosus, taking its origin from the knobs which are developed more or less numerously, and of dif- ferent size in the -cellular tissue. 2399. The diagnosis of scirrhous tumours is frequently accompanied with difficulty. When the skin covering the swelling is puckered, has a dark-leaden Colour, a knotty and irregular surface ; when sometimes there is lancinating pain in. the tumour, and it is firmly attached to the neigh- bouring parts, there can indeed be no doubt of the scirrhous nature of the swelling. But the hardness and condition of the surface of scirrhus often varies, and may be equally present in swellings of other kind. In many instances scirrhus is moveable, not connected with the underlying parts, painless, and the skin often not at all altered. The disposition of scirrhus to run into cancer, usually given as a mark of distinction from benignant induration, cannot be decided beforehand; this transition is not even necessary thereto, and not unfrequently depends on acciden- tal influences, to which the tumour is subjected. Scirrhus does not, in general, easily acquire that size which other swellings do; and the latter do not readily acquire the same heaviness, nor have they the disposition to draw the neighbouring parts into the same diseased meta- morphosis. Examination of the swelling after removal gives a distinct explanation of its nature, as does also the recurrence of a like tumour after removal, which, indeed, is then only of importance as to the prog- nosis. The cancerous sore itself has no such decided and characteristic mark that a mistake may not sometimes be possible with much neglected syphilitic or scrofulous ulcers, as these, oftentimes, without being actu- ally cancerous, present the same symptoms as cancerous sores. In these (a) Nosologic Naturelle. DIAGNOSIS OF SCIRRHUS AND MEDULLARY FUNGUS. 503 cases, the improvement or injury effected by anti-syphilitic or anti-scro- fulous treatment, as well also, as the circumstance, that in cancerous sores, the pain is alone diminished by softening and soothing remedies, but increased by all irritants, will direct the practitioner. Scarpa («), who commonly applies the term scrofulous or strumous tumour to a great extent, and also refers to cases which must manifestly be reckoned with medul- lary fungus, states the following, as distinguishing characters between it and scirrhus. Scrofula rarely attacks the external conglomerated, but usually the lymphatic glands. and in general, several of them at the same time, and in different parts of the body; there may be also an existing scrofulous habit. The hardness of the scrofulous tumour is regular and flat, and different from the peculiar hardness of scirrhus. The scrofulous tumour, from the first, produces a wearing, numbing, heavy pain. Scirrhus only attacks persons of advanced age, rigid fibre, and sanguineo-choleric tempera- ment, in whom, if there be suspicion of a dyscrasy, it is not that of scrofula; scirrhus appears alone, grows slowly, and scarcely perceptibly in every direction, is not sensi- tive, and when long existent, has in general, knots on the surface, and is adherent to the skin in many places. When stabbing pains come on in scirrhus, it no longer increases, indeed, even contracts, with a hardness, from which it may be said, it is disposed to dryness. In injecting a strumous gland, the fluid at first passes freely, but suddenly runs out, because the vessels are torn. When cut through, such gland presents a compact very vascular substance, penetrated with albuminous fluid, which sometimes, though rarely, is mixed with a fatty, granular, or whey-like matter. Between the bodies of the strumous glands, and their external covering, some trace of coagulable lymph is always found, which favours adhesion; but this is also often in the interior. In scirrhus, the injection penetrates only into the principal arterial trunks. In maceration, the substance of scirrhus retains the peculiar hardness of softened cartilage, whilst strumous glands dissolve into, a soft,, fungous, fringy substance. [The following are the diagnostic characters given- by Hodgkin, of scirrhus and medullary fungus, or fungoid disease, as he calls the latter. "One of the most striking features which distinguishes the fungoid disease from true scirrhus, is to be found in the extent and rapidity of the development of fungoid tumours. Whilst, as has been seen, the true scirrhus often remains for a considera- ble length of time in a chronic and indolent state, and. after a growth of some years produces a tumour of only a moderate size, the fungoid tumour in the space of a few weeks is sometimes seen to attain to a prodigious size, and to pass through all the stages which belong to it in common with the other members of the same family of adventitious structures. Whilst true scirrhus is almost exclusively the disease of advanced life, the fungoid disease makes its appearance in individuals of every age; but its most formidable and extensive ravages are seen in the young. Whilst in true scirrhus the fluid matter forms a very inconsiderable and scarcely notable part of the structure, in the fungoid tumour it is frequently pretty abundant, presents a great variety in its characters, and is often collected in cavities of considerable size. In the scirrhous tumour, the peculiar mode of formation I have pointed out, must often be inferred by analogy, guided by faint and partial traces.; but in the fungoid disease we meet with those unequivocal, manifestations, which almost speak for themselves. In true scirrhus, the traces of vascularity, are very faint, but in the fungoid disease, the adventitious membranes possess a higher and preternatural de- gree of vascularity. The vessels which we see ramifying in them, are not only numerous, but large. By some they have been considered principally arterial; by others venous. I will not attempt to decide to which class of vessels they are most allied. They appear to consist of capillary vessels of Bichat on a large scale; and as we sometimes meet with these membranes of a bright and arterial red, and at other times of a venous or livid hue, it seems probable that accidental or fortuitous cir- cumstances have the principal share in determining to which class of vessels these capillaries should most incline. These newly-formed vessels, though large and numerous, are extremely weak and tender, and derive little or no support from the structure through which they ramify, or by which they are surrounded; hence they are liable to give way at numerous points, whence proceed more frequent and exten- (a) Above cited. 504 CHEMICAL COMPOSITION OF SCIRRHUS—SKIN CANCER. sive haemorrhages which so often characterize these tumours, and have led to the term of fungus haematodes, which has not inaptly been applied to many of them. Sometimes the haemorrhage from these vessels produces an effusion into the cavity of the membrane reflected over an inferior order of pedunculated cysts or bodies, and distends it into a cavity filled with blood, the characters of which will vary accord- ing to the time which has elapsed between its effusion and the making of the exami- nation. At other times the effused blood infiltrates the more solid parts of the tumour, and produces an appearance which by Laennec has been well compared to an apoplectic clot. The more solid parts of the tumour differ in a marked manner from that which composes the scirrhous tumour. In this disease, the se- condary cysts, which are often of large size, generally become filled with a material which at first bears a considerable resemblance to tender or feebly coagulated fibrin or plastic lymph. Into this substance new vessels speedily shoot; but being neither susceptible of perfect organization, nor calculated to remain inert and dormant, it speedily, but gradually loses its vitality, and, like other transparent parts in which such a change is effected, gradually becomes opaque, and bears, in consistence and appearance, a close resemblance to the substance of the brain of a child ; hence the terms, cerebriform cancer, encephaloid tumour and medullary sarcoma. * * * Although in fungoid disease, the solid part of the tumour often bears a striking resemblance to cerebral substance, we frequently find it, on the one hand, deviating into a much more firm material, and, on the other hand, into one of a softer and gru- mous consistence. Sometimes it has a minutely foliated structure of a pearly white colour. When the diseased structure has completely lost its vitality, it breaks down into a variously discoloured pultaceous grumous mass, in which the remains of the membranes of the secondary cysts and their vessels may often be detected. Although in a recently formed tumour, or in the newer parts of an older one, the traces of that mode of formation on which I have insisted are sufficiently evident, they are very much lost or obscured, as the progress of decay advances. It is also at times difficult to distinguish it when the tumour has only advanced to the stage of opacity, provided, the substance of the tumour be very uniform, and the membranous parts not only very thin and tender, but adherent amongst themselves and to the contained substance." (p, 333-57.) The following is the analysis of scirrhus by Fov (a) :— Albumen ------ 42,00 White fatty matter - -. - 5,00 Red....., - , 3,25 Osmazome - - - • -. - 0,00 Fibrin.......5,85 Water.......5,00 Oxide of iron ----- 1,65 Subphosphate of lime - - 16,60 C soda - - - 5,00 Carbonates of < lime - - - 6,60 (magnesia - 0,85 Hydrochlorates of j J°*sh "_ *'™ Tartrate of soda - • - - 0,85 Hence it appears by reference to the analysis of medullary fungus (p. 719) that scirrhus contains less of the first three substances, that it has no osmazome; that the subphosphate of lime is nearly three times as much ; and that the total amount of the salts is double that in medullary fungus."] 2400. Cancer in the Skin arises from true scirrhus, which appears as a round or oblong flattened firm swelling, also from warts and other excre- scences of the skin, sometimes from dark red, blackish spots, or from scurfy excoriations. It may occur on all parts of the surface of the body, but especially in the face, on the nose, on the lips, and on the organs of generation, either on account of the peculiar sensibility of the skin on these parts, or because it is here so much affected by external influences. At first a superficial ulcer forms, which enlarges, becomes painful, and is not improved by any remedy. Its progress is'sometimes slow, sometimes quick, and relative to the severity of the pain and the violence of the suppuration. These ulcers are long confined to one definite spot, and remain superficial; the surrounding skin is some- times but little changed, its surface red and even, sometimes co- («) Archive* Generates de Medecine, vol, xvii. p. 185. CANCER IN NERVES. 505 vered with a'dry grayish crust, which is reproduced as often as it is re- moved. As soon as these ulcers take effect on the edge of the lip, the nose, the eyelid, the anus or the urethra, they make quick progress, in- crease in depth, destroy all parts without distinction of structure, and are characterized by their condition, by the lancinating pain, and by the infection of the neighbouring glands. Whilst the ulcers are still small, they are generally only made worse by common treatment. They are frequently found existing at the same time with external and internal cancerous disease. Ulcers, specially on the face, and wings of the nose, and the like, which without pain, without a hard base, without everted hard edges, without fungous growths, without secretion of ichor, spread in all directions, and destroy the parts without distinction of their organization, without our knowing where they will go, have, in common with cancer, only the destructive spreading, and the general circumstance that they can ordinarily be brought to heal, only by destroying their surface. These are phagedenic ulcers, stinking, eating, tettery sores, and' form-, a Contrast with the scabby Herpes exedens, which on the face often causes the most frightful destruction, and in general can only be made to heal by destroying the diseased portion of skin. 2401. Cancer in glands always, begins, as scirrhus, and presents the symptoms above described ( par. 2392.) 2402. Cancer in mucous membranes is developed either in form of polyps, which are hard, uneven, dusky^ red, and painful; often bleed of themselves, or, on the slightest mpvement; ulcerate quickly; exhibit the same symptoms as a, cancerous ulcer, and on examination, present the same condition as scirrhus; or, under the form of hard, wart-like ex- crescences, or as hardening of the mucous membrane, which runs into ulceration. 2403. Cancer in the bones shows itself as osteosarcoma, or, osteosteatoma; and these tumours may have primarily a scirrhous condition, or the can- cerous: nature may be developed in them at a later periods 2404'. Cancer of the nerves exists as a hard^ firm swelling, which inter- nally shows its scirrhous nature, and seems to belong tothe neurilcma rather than to the medullary substance. Sometimes the tumour is seated on a stalk with which the neurilemma is confluent; $oa>etimes it is formed by the swelling of the nerve itself. Their size^varies from that of a pea to that of a nut, and"larger. These swellings,arise sometimes of them- selves, sometimes after external violence, most commonly on the super- ficiaf nerves of the upper limbs. They increase slowly, feel hardish, are tense, seem often filled with fluid"; they are very painful, specially on motion, and particularly on. being moved* from above downwards; a sudden movement of the swelling in this direction produces on the brain and nervous system a sensation like that of an electric shock. The tumouradheres to the neighbouring parts, and draws them into*the same diseased'condition,, Not all tumours of nerves have' this, cancerous character. They are often mere consequences of previous inflammation, and originate in increased and* altered nu- trition; ihey are often formed by unnatural exudation, in which case- examination shows a cavity, of which the walls, are-the neurilema, filled with thin, coagulable fluid, like the serum of the- blood;; or between the nervous threads, which are pressed apart a softishi, but constancy becoming firmer substance is. formed ; or in the nervous threads themselves oblong vesicles are formed, which at first are soft and transparent, but afterwards become harder, and by their increasing size, affect the whole substance of the nerve, and the nerve above penetrates into the swelling, 43* 506 TUMOURS ON NERVES. and below passes out of it. Their size varies from that of a pea to that of a nut, and bigger. I have seen a tumour in the lower third of the thigh, on the ischiatic nerve, as large as a small melon, which had proceeded from the nervous mass itself, and was covered with neurilema. The characteristics of these tumours is always great painfulness on examining and moving them with the finger; they however cause, especially when seated on large nerves, severe pain on moving the part, even without displacement, especially on voluntary motion. The pain is very severe, radiating in the course of the nerve, and frequently accompanied with cramp and convulsions of the part. Sometimes there is less pain than a sensation of formica- tion, and going to sleep, or even a palsied state of the part to which the nerve is distributed. The removal of the tumour is the only remedy; destructive remedies of all kinds are useless, and eseharotics act injuriously. The removal consists in laying bare the swelling, and where it protrudes from the nerve, and is separable from it, in cut- ting it off. If this be not possible, or the tumour spring from the nerve itself, then the nerve must be cut thro.ugb.y_/irstf above, and then below the tumour, and the inter- mediate portion, together with the swelling, removed. Small swellings on the nerves of the skin may be taken away with the corresponding piece of skin. In large tumours of principal nerves, as in the case of the ischiatic nerve which I have mentioned, amputation is the only remedy. [I am doubtful whether the following cases mentioned by Cheselden (a) be tumours on the small branches of nerves; but the symptoms scarcely permit them to be considered any other:—"Immediately under the skin, upon the shin-bone, I have twice seen," says he, "little tumours, less than a pea, round and exceeding hard, and so painful that both cases were judged to be cancerous; they were cured by extirpating the tumour. But what was more extraordinary was a tumour of this kind under the skin of the buttock, small as a pin's head, yet so painful that the least touch was insupportable, and the skin for half an ineh round was emaciated; this, too, I extirpated, with so much of the skin as was emaciated, and some fat. The patient, who before the operation could not endure to set his leg to the ground, nor turn on his bed without exquisite pain, grew immediately easy, walked to his bed without any complaint, and was soon cured." (p. 136.) There is in the Museum at St. Thomas's a fine example of a tumour in the popli- teal nerve of a man, which caused such severe pain and tenderness, with occasional spasm, in the limb, that amputation was performed by Astley Cooper. The tumour is about the size of a walnut, whitish and hard, and of a somewhat scirrhous charac- ter; it seemed to have formed amid the cords of the nerve, which do not appear to enter it, but are expanded over its surface. Liston (b) observes, that "these tumours (of nerves) vary in structure; they consist of a cheesy or albuminous deposit in the neurilema; sometimes they are hard, fibrinous, or earthy, or again, their seetion presents a brainlike and bloody mixture." And he mentions a case in which the tumour, soft and bloody, was situated "in the popliteal space, grew rapidly to the size of a cricket-ball, and im- peded the motions of the limb. On pursuing the dissection, the tibial nerve was found intimately connected with the growth, tbe fibril'Ise stretched upon its sheath, and entering into its substance. The nerve was cut across above and below, and the whole mass extirpated unbroken and entire. * * * The removal of the tumour from the ham, with at least three inches of the tibial nerve, was not for an instant followed by the slightest deprivation of either sensation or power of motion in the limb and foot." Whilst in the hospital, a tumour was found on the front of the same thigh ; an inflammatory swelling took place there and suppurated, but the lump remained. "Within six months after the wound in the ham had healed, the patient returned with an enormously swollen limb, and a large elastic morbid mass in the back part of it; from this a bleeding fungus was protruded, and he soon died. The original tumour was soft and bloody; the one from the fore part of the thigh ovoid and larger than a hen's egg, involved the anterior crural nerve, and was appa- rently fibrinous; the diseased structure, which was reproduced in the popliteal space, had all the characters of fungus haematodes." (pp. 350, 351.) Tumours not malignant have been occasionally removed from nerves with success. It will be here convenient to notice the formation of Tumours on the extremities of (a) The Anatomy of the Human Body. (6) Practical Surgery. Fourth Edition, 8vo, Eleventh Edition, 1778. 1846. TUMOURS ON NERVES. 507 the nerves of stumps, which occasionally, though rarely, occur, and I do not recollect to have seen more than two or three such cases. At an indefinite period after am- putation, either before or after it has healed, the stump begins, without any apparent cause, to become painful, and though it had previously been well shaped, it now begins to assume a conical form, the soft parts retract, the bone sticks out covered only by the scar, which is generally a little inflamed, and the skin above it is extremely tender and painful, when touched. Langstaff (a),in noticing this con- dition, says:—"Sometimes, a spiculum of bone projects horizontally, generally taking the direction of the artery, vein, and nerves of the limb, which thus become implicated with the bony deposit; and sometimes I have found a large spiculum of bone, with a very sharp point, taking an oblique direction, and connected with a muscle, occasioning morbid changes in its fibres, and being a source of great suffer- ing to the patient. In all such stumps I have found the nerves greatly enlarged at their extremities, giving them a ganglionic appearance, and generally firmly adherent to the surface of the stump, and frequently in union with spicula of bone." (p. 131.) In the two cases which I have had the opportunity of dissecting, there was certainly no bony spiculum .irritating the nerve, and there did not appear any satisfactory reason why its enlargement should have taken place. The tumours seemed to be caused by interstitial deposit of fibrinous matter among the fibrils of the nerves, which were principally spread out on their surface. Astley Cooper amputated his case at the shoulder-joint, and there was no recurrence of the symptoms. Henry Cline thought that the retraction of the stump depended on the irritation of the diseased ends of the nerves, and that if these were removed, amputation would not be needed. He, therefore, cut through the skin over the swellings, also through the nervous trunks above them, and left the bone and other parts undisturbed. The result proved the justness of his opinion. There was no recurrence of swelling of the nerves, nor pain, and the stump gradually filled out, ceased to be conical, and resumed the ordinary appearance. From comparison of these two modes of practice, I should not think it warrantable to perform a second amputation at any distance above the,stump; I should be inclined to follow Henry Cline's method; and if there were reason to think this could not be sa'isfatorily managed, I should merely amputate sovhigh above the nervous tumours as would appear necessary to ensure cutting through the healthy nerve. I have an indistinct remembrance that Tyrrell pursued the latter practice in one instance successfully, but I have not any note of it, so that I mention it with doubt. Sometimes, however, neither of these methods are of any permanent service, as the painful affection of the nerves is not confined to their extremities. A remarkable case of this kind is mentioned by Mayo (b), in which, on account of this condition, amputation was performed a second time. "On examination, the seiatic nerve and the saphenous nerve were found to terminate in large callous bulbs. In the second operation, care was taken to draw out and remove a considerable portion of the sciatic nerve, which, retracting, lay well eovered among the muscles. Nevertheless, when the stump had nearly healed, the old pain again commenced." (p. 140.) He after- wards cut down on the sciatic nerve, where covered by the lower edge of the m. gluiaeus maximus, divided and removed a portion of it, but with only temporary benefit. He thought that amputation at the hip-joint might possibly have cured this, as amputation at the shoulder-joint had put an end to a similar neuralgia in the fore-arm, which had been unsuccessfully amputated a seeond time. I must confess I should feel little disposed to perform a third amputation in a ease of this kind.— J. F. S.] The following writers may be consulted on tumours of the nerves :— Viel-Hautmernil, Considerations ge'nerales sur le Cancer. Paris, 1807. Alexander, Dissert, de Tumoribus Nervorum. Ludg. Bat., 1810. Spangenberg, Ueber Nervenanschwellungen; in Horn's Archiv., vol. v. p. 306. Neumann, Geschichte einer Nervenanschwellung; in von Siebold's Sammlung seltener chirurg. Beobacht., vol. i. p. 54. Weinhold, Ideen iiber die abnorme Metamorphosen der Highmorshohle, p. 184. Aronsohn, J. L., Observations sup les Tumeurs developpees dansle Nerfs; avec fig. col. Strasbourg, 1822. 4to. (a) Med.-Chir. Trans., vol. xvi. (b) Outlines of Human Pathology. London, 1827. 8vo. f 508 CAUSES AND Chelius; in Heidlb. klinisch. Annalen, vol. ii. Wood, William, Observations on Neuroma, with cases, &c.; in Transact, of the Med.-Chir. of Edinburgh, vol. iii. p. 367. Baumeister, Dissert, de Tumoribus Nervorum. Bonnae, 1833. Hasler, Dissert, de Neuromate. Turici, 1835. Struck, Dissert, sistens observationem Fungi medullaris Nervi mediani. Gry- phiae, 1836. Knoblauch, A., Dissert, de Neuromate, et gangliis accessoriisverisadjecto cujus- vis casu novo atque insigni. Francof. ad M., 1843. 2405. Cancer is a disease of specific character, depending on a peculiar disposition, the nature of which is entirely unknown; it may be asserted to be hereditary, in different degrees, in one and the same person, and at different periods. This disposition is the cause why the treatment of cancer is ordinarily without benefit, why the disease appears in several parts at once, and why even the early removal of scirrhous swelling is usually unsuccessful. In the progress of the disease a peculiar dyscrasy {par. 2394) is set up by the absorption of the matter produced in the diseased organ. Opinions upon the causal nature of cancer aie different. Some denying a peculiar disposition, consides cancer to be a local complaint, which, only produces a decided dyscrasy from its spreading. Others allow no specific nature in cancer, some hold it infectious, others not. Even the assumption of a specific dyscrasy arising out of cancerous parts, is. denied, because the neighbouring glands often swell, before the scirrhus is disposed; to ulcerate; because, further, the glands often even when the disease has long existed., are not attacked, and. the experiments of the capability of the poison of cancer to infect contradict this assumption (a). Many deny the absorption of the cancerous ichor, and a dyscrasy depending on it (b), whilst Langenbeck (c) showed microscopically the presence of cancerous matter in the veins, and after injecting into the veins of a dog found tumours in the lungs, the cancerous nature of which was shown by m-iscroscopic examination. The swelling of the neighbouring glands may indeed be also produced by pressure, and by the propagated irritation. Relapses of the disease after removal commonly depend on what has been left behind. In those cases, however, where the scar has been for many years, till the disease again breaks out, it is more pro- bable that the cause of its recurrence is a decided predisposition (1). [(1) Upon this point John Hunter (d) observes:—"Some suppose cancers to be hereditary; but this lean only admit according to my principles of hereditary right; that is, supposing a person to possess a strong disposition or susceptibility for a particular disease, the children may also; but I have not yet ascertained the generality of this fact. In many persons it would seem that some of the predis- posing causes are sufficient to become the immediate ones; as when the diseased action takes place at a Gertain stated time, without any immediate cause." (p. 623.)] 2406. The occasional causes of scirrhus and cancer are, all mischief which produces a constant but not intense irritation, blows, continual pressure, bruises,; irritating treatment, or any injury of an ulcer, a hard- ness or an excrescence ; internal diseases, especially scrofula and syphilis, as the consequent swellings and affections may assume a scirrhous charac- ter. Cancer is- most frequent at the critical periods of life, when the capability of production declines, and especially in organs destined for production and propagation, as the womb, testicle, and breast. Women are more subject to it than men ; in like manner, also, persons who are very sensitive or melancholic, lead a sedentary life, atnd have suffered much care and trouble {!}. (a) Alibert, above cited; p. 558. (c) Schmidt's Jahrbucber, vol. xxv.parti. (6) Steffani; in Revue Medicale. 1844; (d) Lectures; in his Works by Palmer, vol. ii. p. 351. vol.i. PROGNOSIS OF SCIRRHUS AND CANCER. 509 [(1) "The cancerous age," says John Hunter, "is from forty to sixty in both sexes, though it may occur sooner or later in certain cases. The testicle for instance often become cancerous at twenty or thirty, but then not from the dis- position of the part alone, but from accident. * * * We often see tumours in the breast at thirty, and probably some of them are cancerous, although scrofula is more to be suspected." (p. 622.) He further observes:—"The parts most disposed to cancer are those peculiar to the sexes, as the breasts and uterus in women, and the testicles in men. Cancers are more frequent in women than in men, in the pro- portion of three to two; owing, perhaps, to the more frequent changes taking place in these parts in the former. It is that change which renders them unfit for concep- tion, and changes the whole system, which is particularly obnoxious. Thus the three disposing causes are: first, a peculiar part; second, the age of the patient; and third, the peculiarities of the part of this age." (p. 623.)] 2407. The prognosis in scirrhus and cancer is always unfavourable, and proportionally so according to the importance of the organ affected, the bad constitution of the patient, when there is hereditary disposition, when the symptoms accompanying cancer are very painful and destruc- tive, and when general dyscrasy has set in. The more superficially the scirrhus or cancer is seated, the less hereditary the disposition or general disease accompanying it, the more it is the consequence of local disease, the better the constitution, and the more recent the disease, the more favourable is the prognosis. When several cancerous ulcers or scirrhi exist at the same time, and the cancerous dyscracy has already affected the whole body, the disease is, according to my present experience, incurable. Scarpa assumes that scirrhus in its first period is merely a deposited, malignant kind of germ, which is produced in the constitution, but is developed by the living powers, and is most intimately connected with any one of the conglomerate glands, or upon any one part of either the external or internal skin, where it is concealed and remains latent; but that in cancer, the hitherto harmless and latent deposit is converted into a cancerous ichor, and produces general dyscrasy. He supposes also that the removal of the scirrhus whilst in its painless state can aldne have a successful result. [Travers has most justly observed, that "not unfrequently the scirrhous tumour is perfectly inert from the period of its formation to the close of life, undergoing very slight, if any, increase, and giving, when mental apprehension is appeased, no trouble to the subject of it. A lady under his observation had been many years so situated, enjoying uninterrupted health, though considerably above seventy years of age." (p. 214.) Brodie (a) mentions one case in which the patient had scirrhous disease of the breast for several years, he believes ten or fifteen; and another, " who had a scirrhous tumour of the breast twenty-five years, and she died at last, not from the disease of the breast, but from effusion into the cavity of the chest." (p. 211.) Such cases, I suspect, are more frequent than generally believed. I have known a few instances, one of which indeed was in a relative, who suffered only occasional slight shooting in the breast, for at least twenty years, during which the tumour did not increase in size after its early growth to the size of a walnut. So long, there- fore, as the disease remains in this quiet condition, I am disposed to believe that it is best left alone; for scarcely any, if indeed any, treatment has other effect than exciting an increase of the diseased action, and hurrying on the fatal result. Very few surgeons have any reliance in the employment of internal and external remedies for the cure of cancer, even when in the scirrhous state; and the large experience of those who, in the course of operating practice, have extirpated cancerous tumours in their several stages, has been most lamentably unsatisfactory, the disease speedily recurring in the 6car of the operation-wound, and the patient often quickly cut off.— j. f. s.] 2408. The cure of scirrhus and cancer requires either the dispersion (a) Lectures illustrative of various subjects in Pathology and Surgery. London, 1846. 510 RECURRENCE OF SCIRRHUS AND CANCER. of the tumour by internal and external remedies, or its removal by the knife or escharotics. [Leroy d'Etiolles (a) has given the following interesting facts relative to the treatment of cancer:—"The mean duration of the life of persons not operated on is five years for men, and five years and six months for women; whilst, on the con- trary, with those who have undergone the operation, the mean is five years and two months for men, and six years for women. It must, however, be borne in mind, that the class of those not operated on includes cancer of the viscera, which is so certainly and promptly, for the most part, fatal. By withdrawing these, the mean duration of men not operated on is six years, or one year more than in those upon whom the operation has been performed. If, however, it be inquired, what time elapses between the appearance ,of the disease on the one hand, and on the other, between the operation and death, on taking the mean of the results of three hundred operations on men, the duration of life will be found to have been three years and nine months before, and one year and five months after the operation. For women, the result of four hundred and twelve operations, gives, before the operation, three years and six months; after the operation two years and six months. Extirpation does not, therefore, prolong life. (pp. 454, 55.) Of eight hundred and one cases operated on, one hundred and seventeen were performed in less than a year after the appearance of the disease; of these one hundred and seventeen there are sixty-one which have returned; but as of the number eight hundred and one operations, one hundred and twelve had been performed within less than a year, at the time when I received the observations of the physicians, we must believe that the proportion is at the present time still greater. If, however, we examine the results of operations per- formed many years after the appearance of the disease, that is, at a period in which it was capable of producing its degeneration, we find among the operations not followed by return, there are fifty-two performed more than five years after the development of the disease. * * * In spite of the transformation in similar tissues attacked by the cancerous affection, there are immense differences as to its termination. The lips afford the proof. Of six hundred and thirty-three men affected with cancer, one hundred and sixty-five were attacked in the lip, that is |56ff. Of two thousand one hundred and forty-eight cancerous women, there were only fifty-four cancers of the lip, one and half hundredth. Of one hundred and sixty- five men; one hundred and eleven were operated on with cutting instruments, twelve by caustic. Of the one hundred and fourteen operations there were fifteen returns, or about one-eighth, when the documents reached me. Of thirty-four lips of women, twenty-two were operated on, and one of them with caustic, seven returned, or one-third. The difference in the frequency of the disease must evidently be referred to the use of the pipe, and especially those called brule-gueule, (dudeen of the Irish,) which workmen and men of that class constantly use. This difference of the cause accounts for the difference of the results. The return of the disease in men is less in proportion, because the greater number of cancroid dis- eases of the lip produced and kept up by an external cause are not true cancers; and yet the symptoms, the characters of the disease do not make known its nature. " Cancers in the tongue are also more frequent in men than in women; but the proportion of success we have just mentioned no longer exists here. In both sexes cancers of the tongue have a termination equally sad. Of six hundred and thirty- three cancers observed in men, eighteen had been developed on the tongue; of two thousand one hundred and forty-eight cancers in women, two only attacked that organ ; nine operations were performed, three by caustic, six with the knife; eight men and only one woman. Of these nine operations, three were performed since less than a year; six died after its return. "Of tumours of the breast we have the following results:—Of two hundred and seventy-seven operations, seventy-three were performed within less than two years; I cannot give the result. There remain two hundred and four. Of these two hun- dred and four, twenty-two died in the year after the operation ; eighty-seven had a return, the whole number one hundred and nine, or more than half. Twenty-seven were operated on in the first year of the appearance of the disease. " If, however, I were called on to draw a practical inference, a rule of conduct, from the documents I have collected, I should hesitate to make it, for 1 believe (a) Bulletin de l'Academie Royale de Medecine, vol. ix. 1843-44. TREATMENT OF SCIRRHUS AND CANCER BY CAUSTIC. 51.1 there are individualities in diseases as well as in other things ; but if it were abso- lutely requisite, I should say that, excepting cancers of the skin, including those of the lips, it would be advantageous not to operate. I do not, however, wish to put myself in this situation, and at present would confine myself to the following con- clusions,,/?^, that the extirpation of cancroid tumours does not arrest the progress of the disease ; second, that there.is no advantage in performing the operation from the first, if it were not for the cancerous buttons, or cancerscof the skin : third, that it was not necessary to extirpate cancerous organs, but in cases where haemor- rhagies, caused by the ulceration, put the patient's life in danger."—(p. 456-58.)] 2409. The treatment for effecting dispersion is precisely the same as that already given, (par. 68,) for getting rid of hardening. This mode, when not employed with the greatest care, is easily dangerous; for true scirrhus is not dispersed by it, and the continued employment of violent remedies destroys the constitution, and favours the passage of the disease into open cancer. When this treatment, that is, leeches, blood-letting, spare diet, purging, and remedies acting on the lymphatic system, softening and soothing applications have effected the dispersion of scirrhous swellings, there can be no doubt of the correctness of the diagnosis. This mode of treatment therefore can only apply in those cases where removal is impossible, and the cancer has been very tedious in its progress, as in such cases experience has proved that with this pal- liative treatment the disease may exist for many years without particular inconvenience, whilst by an active treatment it may be urged on to a frightful extent. Compression of scirrhus, increased gradually to a very great degree, as recom- mended by Samuel Young (a), has been, on repeated experiment, not found to correspond with our expectations, but even causes a quicker and more serious pro- gress of the disease (6). Recamier's more recent experiments, however, speak more favourably for this practice. It appears from his numerous observations, that in incipient scirrhous swellings, compression can restore the tissue of the diseased part to its natural condition without depriving it of its nourishment; in further ad- vanced swelling, the tissue diminishes, and passes into a cartilaginous condition. When the organ has lost its proper structure, and is converted into a cartilaginous or lard-like substance, it may be lessened by compression, without restoring its- organization, and may become atrophic. The adhesions of the swelling with the surrounding tissue is not only not increased, but lessened, and even the thin adhe- rent skin may be restored to its natural state. By this diminution of the adhesions, an actual enucleation of the tumour, after previous division of the skin with escha- rotics or the knife, may be effected with the fingers. Recamier also believes that the return of a scirrhus which has been removed after the previous employment of compression is less to be feared, than when it has been removed without it. Com- pression may be employed in the most careful and gentle manner, and most effec- tually by linen or flannel bandages with soft German tinder beneath it, and accom- panied at the same time, according to the circumstances of the case, with the inter- nal and external use of suitable remedies, hemlock, mercury, iodine, depletives, repeated application of leeches, and the like (c) [If pressure be at all employed in the attempt to cure scirrhous tumours, the best mode of its application is probably by means of the circular air cushion, invented by Dr. N. Arnott, which can be filled more or less completely, according to the pressure the patient can bear, and over it a sort of wooden bowl corresponding to the size of the part to be compressed, which is fastened on with a bandage. (a) Mi mtes of Cises of Cancer and can- the Cancer Establishment of that Institu- cerou* tendency successfully treated. Lon. tion, vol. i. p. 4. don, 1816-18; 2 vo:s. 8vo. (c) Revue Medicale. 1827 ; vol.i. p. 96.— (b) Charles RELL,Surgicil Observations; Sur le Traitement du Cancer. Paris, 1829 ; being a Quarterly Rei>->rt of Ca«es in Sur- H vols. 8 vo.—Bluff, Ueber die Compres- -gery, treateJ in the Middlesex Hospital, in sion beim Brustkrebse; in von Siebold's Journal, vol. xix. part ii. 1835. 512 TREATMENT OF SCIRRHUS AND CANCER BY CAUSTIC. The only result, however, which I have noticed from pressure is, that whilst it diminishes the depth of the tumour, it spreads it in width, and does no real ser- vice.—j. f. s.] 2410. The removal of the diseased part with the knife, or its destruc- tion with escharotics, are the only remedies which can be employed with the least certainty ; a return of the disease is, however, under the most favourable circumstances, to be dreaded. Both before and after the operation it must be endeavoured by treatment to improve the con- stitution by the proper use of iodine and the like, by purging, and suit- able regulation of the mode of living, to ensure, as far as possible, a favourable result. Both modes of proceeding (the knife and escharotics) are, on the other hand, contra-indicated when the cancer has already made so great progress, that it must be considered a constitutional af- fection, and when so situated, that all the degenerated part cannot be removed. The operation must also be put off', if the health of the patient be disturbed by other causes, and the diseased part be particularly painful. The removal of a cancerous swelling, when it has already made such progress that no cure can be expected to result from it, may, however, in many cases, have the advantage of alleviating, in many respects, the sufferings of the patient, by the removal of the large ulcerating tumour. 2411. The mode of proceeding in the removal of cancerous parts varies, according to their seat and other circumstances, and is to be managed generally according to the directions already for removing en- cysted tumours {par. 2258.) The following points must, however, as far as possible, be borne in mind. Every thing must be removed which is in the least diseased. These changes mostly appear in the cellular tissue, surrounding the hardened parts; so much of it must, therefore, be taken away that the tumour, after its removal, should be still sur- rounded with a layer of cellular tissue. The bottom of the wound must be most carefully examined, and every thing infected removed. The healthy skin must be, as far as possible, preserved, to produce quick union of the wound, and to prevent suppuration and an unseemly scar. It seems also advisable, always to put in issues previous to the opera- tion, and to keep them up properly. The practice of many surgeons, to apply an escharotic paste immediately after the operation, or towards the end of the healing, (Kern,) for the purpose of preventing the return of the disease is unnecessary, if it have been completely removed. Mar- tinet's proposal of covering the wound with a transplantation of skin, for the pur- pose of preventing recurrence, has also not been confirmed by experience. 2412. The destruction of a cancerous part by caustic can only he undertaken in cases where the cancer is superficial, and the whole of its glands uninfected, therefore, especially in cancer of the skin. The re- medy most used is arsenic, in form of Cosme's powder (1); more rarely are employed bichloride of mercury, nitrate of silver, the concentrated acids, and the like. Cosme's powder must be made into paste with water or spittle, and spread with a spatula upon the ulcer, which has been dried with lint, and to such extent, that its hard edges be com- pletely covered ; if bleeding occur during its application, its further use must be withheld. The whole surface is then to be overlaid with spiders' web, or left uncovered. The pain caused by this powder is gene- rally very severe for some hours; considerable swelling takes place in the neighbdurhobd of the ulcer, and an erysipelatous inflammation TREATMENT OF SCIRRHUS AND CANCER BY CAUSTIC. 513 spreads over the surrounding parts. Bags of aromatic herbs, or fomen- tations of warm milk, are the best for soothing these effects. The more severe these symptoms are, the more effectual may the operation of the caustic be expected to be. In eight, ten, or fourteen days the slough separates; the loose pieces only may be cut off with scissors, without disturbing in the least that which remains still attached. When a clean ulcer remains after the separation of the slough, it heals with simple dressing; but if it be not clean the caustic must be repeated. (1) This powder consists of one ounce of cinnabar, half an ounce of dragon's blood, one dram of white arsenic, and one dram of charcoal, very finely powdered and mixed. Among the various remedies proposed for destroying cancerous parts, chloride of zinc, in powder alone, or mixed with flour into a paste, or in solution, has been re- commended (Hanke, Canguoin, and others.) Canguoin employs chloride of zinc in four proportions ; first, equal parts of the chloride and flour; second, one part of the chloride and two of flour; third, one part of chloride and three of flour; fourth, one part of the chloride of zinc, one part of butyr of antimony, and one and a half of flour. In widely spread cancer of the skin, these applications are advantageous, as symptoms of absorption of the arsenic are not to be feared (a). 2413. A peculiar mode of applying Cosme's powder has been pro- posed by Hellmund (b). The diseased parts are to be carefully cleansed, either by washing with water, or if there be a crust, by loosening and re- moving it with a spatula. The diseased part is then, according to its form, to be dressed with pledgets of very fine soft lint, spread with arsenical ointment (1), as thick as a card. The pledgets are to be ap- plied singly to the different depths of the ulcer, and very closely pressed with the probe, so that they may be well applied, and extend beyond the edges of the sore about two lines, or if there be only spots, upon the sur- rounding healthy skin. If the edges of the ulcer be much swollen, it is necessary to apply the arsenical ointment, first upon them, and then to put on the pledget. In this way the dressing is to be applied once a day, and each time the sloughs must be removed. Shortly after the applica- tion of the ointment a burning is felt, which soon amounts to pain, that often becomes severe. According to the degree of pain, and the in- flammation in the immediate neighbourhood, it must be determined whether the salve should be made more active by the addition of Cosme's powder (2), or made milder by mixing with it resin ointment, On the third or fourth day, the pain, swelling, and redness gradually diminish; but the ulcer, which has increased in size, assumes a foul appearance. Its fungous and lard-like bottom which secretes a sort of pus, begins on the fourth or fifth day to become putrescent, or to secrete a thin ichor. On the fifth or sixth day, this is changed into a soft, moist slough, which cannot be removed like the slough of an abscess, but must be again covered with the arsenical ointment. According as this treat- ment proceeds, too rapidly or too slowly, the arsenical ointment must be rendered weaker or stronger. When, on the sixth or seventh day, this white, felt-like slough has been completely formed, the sore must be dressed in the same way as before, daily, with balsamic ointment (3), spread as thin as the back of a knife upon lint or linen. On the ninth or (a) Barraud Riofrey, New Treatment of (b) Bretschler, Acte zusammengest; in Malignant Diseasesland Cancer without Ex* Rust's Magazin^ vol. xix. p. 55. csion. London, 1836. Vol. iii.—44 514 TREATMENT OF SCIRRHUS AND CANCER BY CAUSTIC, tenth day, the line of separation forms and spreads around the whole slough, which on the fourteenth or fifteenth day is thrown off", and the wound-exhibits a healthy suppurating surface. If this surface retain its healthy condition, it must be dressed, till cured, with the balsamic oint- ment ; but if any one part still have a foul appearance, the arsenical ointment must be applied to it for two or three days, and when it is in this way brought into a putrescent state, without a slough being formed, it must be again dressed with the balsamic salve. (1) This ointment is composed of one dram of Cosme's powder and an ounce of the narcotico-balsamic ointment, well mixed together. (2) Hellmund's receipt for this powder is, two scruples of white arsenic, twelve grains of charcoal, sixteen grains of dragon's blood, and two drams of cinnabar, well powdered and mixed. (3) The narcotico-balsamic ointment is made with black Peruvian balsam and extract of henbane, half an ounce each, four scruples of acetate of lead, forty minims of tincture of opium, and four ounces of wax ointment, well rubbed together. 2414. The length of time occupied by this treatment varies; most commonly, however, it does not exceed thirty or forty days, during which, no particular diet is necessary. In scrofulous and herpetic dys- crasy, the remedies already indicated are employed. In erythetic per- sons, the inflammation and fever are often so great, that special treat- ment is requisite. I have several times noticed, during the use of arsenical ointment, violent pains in the belly, and diarrhoea, which I Could not, at least, ascribe to other causes. I can confirm, from nume- rous cases in my own practice, the advantageous effect of this mode of treatment. The gradual and progressive effect which may be increased or diminished at pleasure, and the fact, that it can be applied to deep parts and places where Cosme's powder cannot well be used, are the advantages of this method. In cancer of the skin, in eating and sloughing spots, it is specially efficient: in some cases of cancer of the breast, it may be very curative; in fungous cancer, it has not any effect at all (a). 2415. If cancerous degeneration appear after repeated removal, or repeated application of caustic, or if the cancer be so situated that these modes of treatment are not applicable, we are restricted to the internal and external use of such remedies as specially act, partly against the local, and partly against the general symptoms, which arise from the absorption of the cancerous poison. To the former belong the internal use of arsenic, belladonna, cicuta, and digitalis, of cherry bay water, mercury, calendula, carbonate of iron^ hydro-chloride of gold, fucus helminthocorton, iodide of potash, and the like-. For external application, weak solution of arsenic, poultices of cicuta, belladonna, digitalis, calen- dula, of carrots with bichloride of merCury, and of yeast poultices, pow- dered charcoal, lime water, solutions of narcotic extracts, leeches, liquor of ammonia diluted with water, expressed juice of onopordon acanthium, sulphuret of potash, carbonate or phosphate of iron, made into a paste with water, and continued gradually increasing pressure. With this treatment, the mode of living must'also be attended to> animal food must be avoided, and milk or vegetable diet ordered* 2416. In order to diminish the severe pain of an open cancer, the (a) Chelius; 'in Heidelb. klinisch. Annalen, vol. iii. CANCER OF THE LIPS AND CHEEKS. 515 already mentioned narcotics, opium, belladonna, and hyoscyamus, partly serve. According to my experience, a solution of sulphuret of potash, in rose water, with the addition of extract of hyoscyamus, applied lukewarm, on napkins, is very beneficial for relieving the pain. 2417. When any part of an ulcer passes into a cancerous state in con- sequence of constant irritation, improper treatment, and the like, a soothing antiphlogistic treatment, as repeated leeching, warm fomenta- tions, and poultices, quietude, and the like, must be employed, together with attention to the existing constitutional affection (a). A.—OF CANCER OF THE LIPS AND CHEEKS. 2418. Cancer occurs only on the lower lip, at least I have never seen it as a primary affection on the upper lip. It appears either as a scabby or ulcerated spot, which gradually spreads, throws out fungous growths, and the like, or forms a hard shapeless swelling of the lip, which enlarges, becomes very painful, and breaks. It spreads gradually upon the skin of the chin, the mucous membrane of the mouth, the gums, the glands below the jaw, and destroys the entire lip and the bone. The above described twofold mode of the production of cancer of the lip has been proved, by numerous microscopical observations I have instituted, to be true cancer, and hypertrophy of the natural tissues of the lip.. In the latter, the papillae of the cutis were hypertrophic, and very considerably lengthened. Whilst upon the whole sur- face of the papillae, a plaster of epithelial cells had been formed, which continually grew, and were thrown off as scales ; so was each papilla surrounded at its extremity with a thick sheath of epidermis, and thus a cylinder was formed, into which the base of the papilla, often capable of being drawn like a thread out of its sheath, entered. These cylinders, at first close to each other, were pushed apart by the scaling, though still held together on the surface by a layer of epidermal scales. In many cases, the epithelium formation was very great, and presented an appearance nearly allied to warts and condylomata. Ulcers on the lips are often malignant, without being cancerous; as the continual movement of the lips, and the flow of spittle and the like, prevent their healing, and keep up constant irritation. Syphilitic sores on the lips often assume a malignant character; they mostly begin with a vesicle which bursts, and the ulceration spreads from the skin to the other tissues. Not unfrequently, also, ill-conditioned ulcers are kept up by bad teeth (b). 2419. The only efficient mode of treating cancer of the lip is, the removal of the diseased parts by cutting them out; and this is preferable to the use of caustic. The operation is only contraindicated when the cancerous degeneration has spread considerably on the inside of the mouth, the submaxillary glands and so on, which render the complete removal of the disease impossible. The mode of operating varies accord- ing to the extent of the cancer. 2420. If the cancer do not spread down beyond the red part of the lip, and only affect more or less of the edge of the lip, it is best whilst holding the diseased part with the left hand, or with Graefe's entropium- forceps, and pulling it well up, to cut it off through the healthy part, by a slight sweeping cut with a pair of scissors curved towards their surface. (a) Henry Earle, On the influence of Local Irritation in the production of diseases resembling Cancer; in Med.-Chir. Trans., vol. xii. p. 284. (b) Earle, above cited, p. 271.—Chelius ; in Heidelb. klin. Ann., vol. iii. 516 OPERATION FOR CANCER OF THE LIPS. The spouting labial arteries are to be tied or twisted, and the wound covered with a sponge dipped in cold water till the bleeding ceases en- tirely. German tinder is then to be applied, and when after three or four days, suppuration is set up, a linen rag dipped in lukewarm water should be put on till the scarring is complete. In from ten to twelve days a linear scar is formed by the union of the mucous membrane of the mouth with the external skin, in consequence of which the lip draws up, so that in great loss of substance the alveolar process and teeth are more or less completely covered again; but in less loss of substance there is scarcely any noticeable depression of the lip remaining, as my numerous cases have proved. The ordinary way of removing the cancerous part by two cuts meeting at an angle, causes in these cases a great loss of sub- stance (a). [Notwithstanding Chelius's recommendation, I think the old method of treating these cases with the angular cut is safest; the depth to which the cut should be made of course will depend on the extent of the disease.—j. f. s.] 2421. If the cancer have spread down beyond the red edge of the lip, the whole degenerated part most be removed by two cuts which should meet at an acute angle. In doing this an assistant steadies the lip with his fingers on both sides, compressing the coronary arteries at the same time. The operator with the thumb and forefinger of the left hand grasps the diseased part, lifts it up a little, places the knife upon the edge of the lip, carries it obliquely downwards and inwards, and then makes another cut in the same wray on the other side, so that a V shaped piece is cut out. Its connexion with the gums and chin is then divided, the spouting vessels twisted or tied, and the edges of the wound brought together as in the operation for hare-lip with the twisted suture {par. 727); in doing which the bleeding is generally stopped without any ligature. If the cancer spread from the corner of the mouth over the upper lip, the corner must be removed with a semilunar or an angular cut, and afterwards the V shaped cut must be made downwards. The wound at the corner of the mouth is first to be brought together horizontally or obliquely, and then the remaining wTound readily meets. The extensibility of the lip, especially when separated to a great ex- tent from the gums and jaw, permits its union even in cases of enormous loss of substance, and gradually gets rid of the considerable deformity often at first present. 2422. When, therefore, even in very widely-extended cancer of the lip there is great loss of substance, usually by close attention to the above points, the bringing together of the lip is possible, and the at first much opposed drawing together and deformity of the mouth gradually ceases {b). Cutting into the corner of the mouth for the purpose of increasing its aperture, as by some recommended, is not only useless, but even prevents the due extensibility of the parts concerned by producing a hard scar. But when the loss of substance on cutting out a cancer of the lip is so great that the edges cannot be brought together, nothing remains but to make a new lower lip {Chiloplasty). (a) Richerand, Histoire des Progres recens de la Chirurgie, p. 218. (b) Chelius, Gelungene Lippen und NasenbUdung an dem selben subjecte; in Heidelb. klin. Annal., vol. vi. part iv. OPERATION OF CHILOPLASTY. 517 2423. The different methods and proposals for forming an underlip may be arranged in the following way; first, the Italian mode of Chiloplasty, by transplanting the skin of the arm (Ta&liacozzi, von Graefe ; second, the Indian mode of Chiloplasty (Delpech {a), Tex- tor {b), Dupuytren) (c), in which a piece, corresponding in size to that lost, is taken from the skin of the neck, turned round and united? with the edges of the wound ; third, separation of the neighbouring skin, and adroitly bringing together the cut and uniting it in different ways; «. Chopart's method in which a vertical cut i-s made on each side of the cancer, extending down below the edge of the chin; the cancer is then removed with a transversely-curved cut, the flaps raised to the height of the edge of the lir> and there fastened, the head being at the same time kept bowed forwards. The method of Roux de St. Maximin (d) corresponds with this, as do also those of Blandin and Serre (e), the latter of whom endeavours to preserve the mucous membrane of the mouth, and with it.to cover the upper edge of the wound. /3. Dieffen- bach's (f) method* is the following; after the cancer has been removed, the soft parts are separated to a sufficient extent from the gums and lower- jaw on either side; then, for the purpose of relaxing the edges of the wound, two side cuts are made into the mouth itself; or by drawing together the soft parts from either side, a horizontal cut outwards being made at each corner of the mouth, and then a vertical cut carried-down to the edge of the jaw | \/ [„„ The two flaps: are now drawn together in the middle and united with the twisted suture; their outer angles con- nected with the corners of the mouth, and the upper edge sewn with several interrupted sutures to the mucous membrane., y. By Blasius's {g) method after the cancerous parts have been removed by a semilunar cut from each corner of the mouth, uniting in an angle below the chin, a cut is made beginning from the right edge of the wound, about half an inch above theedge of the jaw, and carried a good; thumb's breadth down- wards, again brought up in a curve to the edge of the jaw, and* continued along it to the edge of the ni^ masseter. This flap is now to- be separated from the jaw, and afterwards a like one having been made on the left side, both are to be drawn inwards andupwards, so that they replace the lower lip, and are then brought together with the twisted suture. Both angles formed by the soft parts on the sides of the chin are now to be dissected up, and so drawn upwards and towards each other that they touch the line of union of the new underlip, and the lower edge of the latter is brought into immediate connexion with the raised skin, in which position the edges of the wound are to be kept together partly by the twisted and partly by the interrupted suture, the head being at the same time bent downwards. (a) Chirurgie Clinique de Montpellier; voT. (/) Rost, Dissert, de Chiloplastice et ii. p. 587. . Stomatopoesi, Lips, 1837.—Zeis,, Hand- (6) Oken's Isis, vol.xxi.; p. 4!)6. 1828. buch. der plastischen Chiiurgie, p. 419.—» (c) Diffb'tnite corrigee par la transport Baumgartkn, Dissert, de Chiloplastice et d'une pirtie du corps sur une autre;, in Stomatopoesi. Lips., 1837. Revue ivledicale, 1830, vol. iii. p, 283. (g) Klinische Zeitschrift fur Chirurgie (d) Velpeau, Nouvi:aux Elejareas de.Me- und Augenheilkunde, vol., i. p., 387,, Halle decine Operatoire, vol. ii. p. 33. 1836.—von Ammov und Baumgarten, Die (e) Seu re; in Gizette Medicale de Paris, plastische Chirurjrie nach ihren bislierigen vol. iii. p. 238. 1835. No. 15. Leistungen, p. 129. Berlin, 1842. 44* 518 CANCER OF THE TONGUE. 2424. In considering these different methods and performances of Chi- loplasty, with the exception of the very difficult and in its consequence uncertain Italian transplantation, it must be remembered that in the inser- tion of a flap tprned round from the skin of the neck, as well as in the mere drawing up of the separated flaps, the bare part of the jaw indeed may be covered, but generally the upper edge of the skin which is firmly connected to* the bone, puckers together, rolls inwards, irritates by the growth of the beard, and can only assume in some degree a natural ap- pearance, if it be possible to stitch it to the mucous membrane of the mouth. These circumstances apply in like manner, though in less de- gree, toBLAsius's method ; and are most favourable in Dieffenbach's operation ; but it is very bad when the side flaps on drawing together do not meet each other, either at the corner of the mouth, or are destroyed by gangrene. In the closure of the side openings, under both opera- tions, nature is very active, and may be assisted by touching with lunar caustic or by making little side cuts (a). 2425. If the cancer of the lip have extended to the bone or have arisen from the bone itself, underwhich circumstances the use of caustic, of the actual cautery and the like, in general merely increase the mischief, the only remaining remedy is the removal of the chin first practised by Dea- dericK and Dupuytren. In order that this operation should be suc- cessful, the skin must be healthy to such distance that it is possible to cover the part where the bone has been sawn off'; and the swelling of the neighbouring glands and the signs of general cancerous dyscrasy do not particularly forbid such operation. The mode of proceeding will be hereafter considered w hen the removal of the lower jaw is treated of. It is further to be remarked that in cases where the bone is not diseased, its removal, however, may be requisite, for the purpose of obtaining room to bring the soft parts together (Roux)v, 2426. In cancer of the cheeks and other parts-of the face, its destruc- tion is commonly undertaken with Cosme's powder ; where however the seat and nature of the disease permits it being cut off, that method is most proper. B.—OF CANCER OF THE TONGUE. 2427. Cancer of the tongue commonly begins, with a hard' circum- scribed, swelling at one side or, other of that organ ; there is lancinating pain ; the swelling breaks and quickly spreads with the peculiar characters of cancerous ulceration^, Various swellings and ulcers which occur on the tongue, very often, assume a malignant appearance; the loose tissue of the tongue, its continual moisture from the spittle, and pointed, de- cayed teeth very commonly keep up stubborn sores. Not unfrequently the papille on the dorsum lingue enlarge and form fungous excrescences. Syphilitic ulcers of the tongue commonly degenerate into cancer. 2428. The prognosis, depends on the seat of the disease, its extent and cause. If an ulcer of the tongue have assumed, in Gonsequence of continual irritation, or, improper treatment., an ill-conditioned character, (a) ZEfcS,,abov£ cited}, p, 426. TREATMENT OF CANCER OF THE TONGUE. 519 it may often be cured by proper local and general treatment; to which treatment the surgeon is restricted in those cases of ulcerated cancer which are beyond the reach of any operation. Every irritant, every mischievously projecting, irregular, or sharp tooth, must be removed, the tongue protected by covering the other teeth with wax, talking entirely forbidden, the mouth often cleansed with lukewarm water, or a solution of extract of hemlock with honey, only bland food taken, and in bad cases all solid food avoided. If the glands beneath the chin be swollen, or the ulcer very irritable, leeches must be applied repeatedly. The patient should frequently during the day hold carrot-pulp in his mouth, which operates partly as a fomenta- tion, and partly as it has the effect of completely preventing the patient from talking and moving his tongue. Instead of the application of a solution of lunar caustic, or of dilute hydrochloric acid, three to four drops in an ounce of water, and sometimes a* solution of arsenic, as recommended by Henry Earle (a), I employ mild soothing remedies with the best effect. Extract of hemlock in increasing dbses may be given internally. For syphilitic ulcers, mercurial treatment, and Zitt- mann's decoction may be employed, and in other cases, the several preparations of gold. If by these remedies the progress of the ulcer cannot be checked, it is decidedly cancerous ; or if there be a scirrhous swelling, the removing of the degenerated part is necessary, provided that no general dyscrasie disease keep up the affection of the tongue, that it be not degeneiated at the root, and that the neighbouring glands and tonsils be not affected. It must, however, be remarked, in refer- ence to the last point, that the application of many leeches at first and of a few afterwards, often disperses this swelling (b). Hevfelder (c) thinks that in scirrhous harctening' of the tip of the tongue, the operation may be deferred as long as there is no traee of transition into cancer. 2429. The removal of the cancerous part of the tongue is managed in the same way as the operation for shortening a? very large tongue [par. 2162); it differs, however, according to the seat and extent of the cancerous degeneration. The patient seated on a stool, and having his head fixed by an assistant standing behind him, protrudes the tongue as far as possible, which is then to be held with the assistant's fingers covered with linen, or with a pairr of polyp-forceps, with which the back of the tongue is grasped, firmly pressed together and fixed; the diseased part is to be held with the fingers, or with, a pair of hook-for- ceps, a hook or a thread passed through it. The degenerated part being now drawn forwards, is to be cut off with a bistoury, or what is better with the kneed of Cooper's scissors ; the direction and shape of the cut being decided by the seat and shape of the disease. When the ulcer or the scirrhus is not large, specially if it be on the tip of the- tongue, it may be removed! by two cuts connected at an angle, so that the wound may be brought together with suture; although Heyfelder holds it better not to effect the union this way, but to leave it to nature. (o Above ci'ed, p. 28i; voli ii. p. 69.—Jaeger, De exslirpatione (b) Li franc ; in Revue Medicale 1827, Lingua1. Erlangen, 1832. (c) Ueber Zungenkrebs; in Studien ira Gebiet eder Heilwisenschaft^voLi. p. 183*., 520 REMOVAL OF THE TONGUE BY TYING. If the cancer be on one side of the tongue, that organ must be divided by a cut lengthways, and a second cut made transversely or obliquely behind the degenerated part. If the disease extend far back, it is necessary first to divide the cut on the corresponding side to obtain more room. If the tongue be degenerated throughout its whole thick- ness and far back, the cheek must also be first divided, and when the tongue has been properly protruded and fixed, it must be cut off with two strokes with Cooper's scissors from the side towards the middle. The bleeding which always accompanies this operation must be stopped as far as possible by ligature, by styptics, by pieces of ice held in the mouth, by solution of alum, or by the actual cautery. The edges of the wound are then to be carefully examined, and every hard knot or diseased part seized with the hook or forceps, and removed with the scissors. The after-treatment must, according to the degree of the ensuing inflammation, be more or less antiphlogistic; the patient must not talk, and only eat mild nourishing broth. When suppuration takes place, bland mouth-washes must be used. If the suppurating part assume a bad appearance, it must be touched with caustic, or with the actual cautery, and at the same time a corresponding general treatment em- ployed. After the cure^ the speech is more or less affected, according as more or less of the tongue has been removed; it, however, gradually improves if the lost part have not been very great. Fungous growths of the tongue must be cut off at their base, either immediately or after the application of a ligature around the tongue, and the bleeding surface touched with the actual cautery (a). Tying the lingual arteries (par. 1444) which has been proposed for the spe- cial object of preventing bleeding in cutting off the tongue, is partly on account of its great danger and difficulty in stout persons, improper, but specially so, because experience has shown that even in deep removal of the tongue the bleeding may be stanched by ligature and other remedies. Jaeger, for these rea- sons, thinks it required only in cases of considerable varicose or aneurysmatic af- fections of the- tongue, or in its total removal, when the remainder of the tongue cannot be laid hold of„ 2430. The remopal of the tongue by tying, which is done either with a single ligature, or with a double thread, passed through with a nee- dle, and tied on both sides, is indeed a security against bleeding, but the painfulness of this method, the inconvenience caused by the swelling of the tongue, by its sloughing and the like, generally leads to the preference of removal, by cutting; cases, however, may occur, where a mixed treatment may be requisite. If, for instance, the tongue be diseased far back on one side, the diseased may he separated from the healthy part by a cut extending sufficiently far back, the diseased mass drawn forwards with the forceps, and a ligature applied with the loop-drawer, at the root of the degeneration (6). Otherwise, experi- ence shows, that in such cases, the removal by cutting has favourable results (c). (a) von Walther ; in his Journal' fur prend a la formation de la parole; in Chirurgie und Atigenheilkunde, vol.. v. p. Revue M dicnle, 1832, vol. ii. p. 384. 210.—Jaeger, above cited.—Delpech, Sur (6) Lisfranc, above cited. un Cas de Cancer de la Langue, qui a (c) Jakger, above cited.— Reiche, Ueber entraine la perte tot.-.le da cet organe, et partielle und totale Exstirpation der Zunge; bui a 1'ourni l'occasion d'etudier k part qu'il in Rust's Magazin, vol, xlvi. part ii. MIRAULT'S MODE OF TYING THE TONGUE. 521 As Cloquet had previously opened the bottom of the mouth for the introduction of a ligature, so Mirault (c) proceeded in a case, in which he had fruitlessly en- deavoured to find the lingual artery on one side, although he had taken it up, with difficulty, on the other, after which, the tumour diminished, but increased again. He made a cut from the chin to the tongue-bone, directly in the space between the m. geniohyoids, through which he pierced the tongue at the middle of its base, and surrounded the left half with a ligature, the ends of which hung down from the neck, and were there tied. Afterwards he tied the other half. If thus tied at two different time^, the cancer may be cured without mortification of the tongue, which retains its shape and activity. According to Mirault, the cut into the bottom of the mouth is assisted, if the tongue be drawn well forward with a hook, and a needle curved side- ways with a handle, like Desault's aneurysmal needle, be thrust through the mid- dle line of the tongue from above, downwards, so that its point protrude below, at the part where the tie is to be made; the one end of the thread is now to be held fast, the needl6 with the other end drawn back, and then the threads tied. With Mirault's, agrees the practice of Regnoli (b) for removal of the tongue. He made three cuts in the form of T from the lower edge of the point of the chin to the tongue-bone, and on either side to the front edge of the m. masseter. The skin, cellular tissue, and m. platysma myoides, were dissected off, a pointed straight bis- toury thrust behind the chin from above downwards, the insertion of the m. genio- hyoids and genioglossi were cut through, and the mucous membrane of the mouth divided. With a button-ended bistoury, the insertions of the m. digastrici and mylo- hyoids, and the mucous membrane of the mouth were now cut through up to the pillars of the soft palate. After tying a few vessels, the tip of the tongue was seized with Museux's forceps, and drawn down to the lower opening, so that the whole tongue was seen on the front of the neck, and pulled well down with the fingers. Several ligatures were now applied with a long curved needle around the root of the tongue; the tongue out off with a small pair of shears in front of the ligature; its stump returned into the cavity of the mouth, and the wound closed. Ice was put into the mouth to keep down the inflammation. [Arnott (c) has also performed this operation for a malignant tumour of the tongue of a girl of fifteen, which was as large as a pullet's egg, projected from the upper and under surface at its right side from nearly half an inch of its apex to the isthmus faucium, and protruded at the edge between the teeth. "The head being slightly extended, and the os hyoides felt, an incision was made over it, upwards and forwards, an inch and a half in length, on the mesial line, through the skin, cellular substance, and raphe of the mylothyoid muscles. With the edge of the knife, but chiefly by its handle, way was made for the finger between the two genio-hyoid and the two genio-glossal muscles. A tenaculum was next passed through the apex of the tongue, by means of which it was drawn out of the mouth, and held so during the subsequent part of the operation. Into the wound in the neck a strong needle, with an eye at the point, in a fixed handle, was now conducted and passed through the basis of the tongue into the pharynx a little to the left of the mesial line: the loop of ligature which it carried was then, by means of a blunt hook drawn forwards out of the mouth, and the needle withdrawn from the wound over one of the ends. The loop being cut, two ligatures were obtained; one of these was placed along the upper surface of the tongue, so as to bound the disease on its left side, and carried through the apex of the tongue, from above downwards, by means of a large curved needle, through which the oral end of the other ligature was now also passed. Fixed in a porte-aiguil/e, this needle was next carried through the floor of the mouth, im- mediately behind the last molar tooth, on the right side, directed at first, and for the greater part of its course, perpendicularly downwards, then inclined mesial, and brought out at the incision in the neck. There were thus two ligatures, the four ends of which being out of this wound: one of the loops was so disposed as to encircle the right half of the tumour; the other was placed longitudinally on the upper surface, of the tongue, longitudinally and obliquely below. Being tied, (and this was done as. tightly as possible,) the diseased mass was circumscribed posteriorly, laterally, and, in some measure, inferiorly. A third (a) Gazette Medicale de Paris, vol. ii. p. (b) Bulletino delle Scienze Mediche. Jan.. 507. 1834. August. No. 32. 1839. No. 181. (c) Med..Chir. Trans., vol. xxii. 1839. 522 CANCER OF THE PAROTID GLAND. ligature was now passed through the fore part of the tongue, so as to isolate, at this part, the diseased from the healthy structure." (p. 23-25.) This proceeding fixed the tongue in the mouth, and she became-unable to articulate or swallow. She was fed for a fortnight on milk by an elastic, catheter passed along the left side of the tongue into the oesophagus. The swelling of the sound part of the tongue, and the salivation which ensued, were moderated by active purging. On the second day, "the circumscribed portion of the tongue was black and pulpy, and portions of it began to separate. This continued until the fifth day, when, on removing some of these, I discovered that the sloughing was confined to the surface, and that the more soft part of the tumour underneath was still alive, as it bled on being scratched. I endeavoured to complete the strangulation by carrying a canula over the ligatures, hanging out of the wound of the neck up towards the root of the tongue, and tighten- ing these afterwards by twisting and maintaining them so, but without a successful result." * * * " On the eleventh day the diseased was completely separated from the sound half of the tongue by a deep trench, so as to give it a truly bifid character, and the trench was continued across the basis, seeming to extend through the whole thickness of the part. * * * Reunion by granulation had commenced between the diseased and sound portions of the tongue, but this was easily broken down by the probe. It was now evident that the former part derived some vascular supply from below, and the following method was employed to cut this off. A loop of silver wire, properly bent, was passed over it from the mouth, carried and depressed into the trench already mentioned as surrounding it, and being drawn forwards, the dis- eased part was found to be placed completely above the level of the loop. The two ends of the wire were next passed through a double polypus-canula, and this being carried home under the tumour, to what may now be considered its neck, the liga- tures were tightened, the death of the part effected, separation ensuing on the fifth day, (the seventeenth from the first operation.") (p. 23-28.) The case succeeded completely, and at present, Oct, 1846, she is quite well.] C.—OF CANCER OF THE PAROTID GLAND. Kaltschmied, De Tumore Glandulae Parotidis feliciter exstirpato. Jenae, 1752. Siebold, C, Parotidis scirrhosae feliciter exstirpatae Historia. Erford., 1781. -----------, (Resp. Orth.,) Dissert, de Scirrho Parotidis. Wirceburg, 1793. Siebold, B., Historia Systematis Salivalis, p. 151. Jenae, 1797. Ohle, Erfahrungeri ueber die Ausrottung der Ohrspeicheldriise; in Zeitschrift fur Natur-und Heilkunde, vol. i. part i. Dresden, 1819. Klein, Ueber die Ausrottung mehrere Geschwiilste, besondes der Schild-und Orspeicheldriise; in von Graefe und von Walther's Journal fur Chirurgie und Augenheilkunde, vol. i. p. 106. 1820. Kyp, (Praesid. Walther,) Dissert, de Induratione et Exstirpatione Glandulae Parotidis. Bonnae, 1822. Braamberg, Dissert, de Exstirpatione Glandulae Parotidis et Submaxillaris. Groning., 1829. 4to. 2431. The parotid gland is subject to a variety of degenerations of its tissue, by which its size is increased, and a larger or smaller swelling is produced. It may be the seat of induration, of a sarcomatous degenera- tion, of scirrhus and cancer, and of medullary fungus. Encysted tumours in the tissue of the parotid, or in its neighbourhood, as well as swellings of the neighbouring glands, may be easily mistaken for a swelling of the parotid itself. 2432. The swelling of the parotid is characterized by there being always a circumscribed tumour between the mastoid process and the ascending branch of the lower jaw, which lifts the ear up, and enlarges in a more or less irregular, oftentimes egg-shaped or pyramidal form. The axis of the swelling always corresponds to a straight line, continued from CANCER OF THE PAROTID GLAND. 523 the mastoid process towards the angle of the lower jaw, or little deviating therefrom, if the swelling be not very large; and it forms a pyramid, the base of which lies upon the ascending plate of the jaw, but its apex pro- jects freely. 2433. The following circumstances serve for the closer distinction of the several tumours of the parotid gland. Scirrhus forms a swelling not very bulky, of stony hardness, irregular on its surface, having clefts and globular projections, almost immoveable, protruding little externally, though it spreads rather deeply, compresses the vessels and nerves, and declares its cancerous nature by the lancinating pain. Induration of the parotid remains after previous inflammation, (par. 141,) feels less hard and uneven than scirrhus, and shows no sign of concealed cancer. In sarcomatous degeneration, the swelling is softer than in scirrhus or indura- tion, its growth is rather quick, it is moveable, and may also be raised from below. Medullary fungus of the parotid forms a swelling which quickly attains an enormous size, and from whence, on its bursting, fungous growths arise, and bleedings frequently occur. 2434. From the above-mentioned swellings of the parotid gland, en- cysted tumours, which are developed in the parenchyma, or oh the cover- ing of the gland are distinguished by having mostly a roundish form and regular surface ; their front surface is often compressed ; they are not developed equally; they feel soft, and fluctuate indistinctly. In tumours of the absorbent glands, there are always several swollen at the same time, the swellings are softer, and there is a general appearance of scrofulous disease. Tumours of the submaxillary glands are distinguished from those of the parotid by the seat of their development. 2435. In scirrhus, as well as in medullary fungus of the parotid re- moval is the only remedy, though a doubtful one. Various means have been advised for the dispersion of induration, as hemlock, antimony, mercury, barytes, and iodine ; for external application, mercurial, or iodic ointments, poultices, dry bags of hemlock, hyoscyamus, belladonna, stramonium, softening steam of these herbs, dispersing plasters. In sar- comatous swellings of the parotid, perhaps some decrease may be effected by repeated applications of leeches, by issues on the tumour, or in its neighbourhood, and by a seton drawn through the tumour. These means lessen the increased nourishment of the swelling, by the inflammation excited by the seton producing obliteration of the vessels, and the swelling is destroyed by the suppuration. Such modes of treat- ment, however, can only be employed with the hope of a favourable issue, in cases of not long standing degeneration of the parotid, and when it has little increased in size. It must, however, be remembered, that attempts at dispersion may cause a quicker growth of induration. When in sarcomatous degeneration, the vessels are very numerous, the introduction of a seton may produce great bleeding. 2436. The removal of the parotid gland belongs to the most difficult and dangerous operations, and is bymany considered totally unpermis- sive, as the close connexion of the gland with the important neighbour- ing parts, renders necessary the wounding of very important vessels and nerves, hence the danger of bleeding, and of fatal nervous symptoms; besides, the swelling of the parotid, in ordinary cases, is productive of 524 EXTIRPATION OF THE PAROTID GLAND. no danger, and is not cancerous (a). Experience has repeatedly proved the possibility of extirpating the parotid without the occurrence of these accidents. The parotid gland is covered wTith a fibrous capsule; if this be not adherent to the tumour, and if during the operation it can be spared, the removal is far easier and less dangerous than when the capsule and tu- mour are united. The vessels which may be wounded during the ope- ration are, the temporal, anterior aural, transverse facial, and external maxillary arteries or their branches, which are often considerably enlarged, and even the carotid artery itself, which is often completely enclosed in the parotid gland. If the surgeon operate with due care, and with inti- mate knowledge of the parts, he may almost always avoid injuring the trunks of these arteries; even, however, if one or other be wounded, fatal bleeding may be prevented by one or other of the under-mentioned remedies. Numerous twigs from the third branch of the fifth pair, the communicating facial, and from the third pair of cervical nerves must indeed be cut through in removing the parotid, but the trunk of the fa- cial nerve is not necessarily divided (6). The removal of a scirrhous tumour of the parotid gland is always most difficult and dangerous, because it is firmly connected with the surround- ing parts, and if any of the disease be left, no cure can be expected. In induration and sarcoma the tumour is more moveable, the surround- ing capsule may therefore be left alone, and does not at all interfere. Allan Burns (c) believes that in all cases where the parotid has been held to have been removed, it Was not the gland itself, but a diseased conglobate gland, of which there are commonly two accompanying the parotid, the one under the lobe of the parotid, and the other on its middle, and lying opposite the division of the ex- ternal carotid, into maxillary and temporal arteries. The former is not so deep, and is simply covered with the cervical fascia and the lobe of the parotid. Burns at- tempted the removal of the parotid on the dead body, but even there failed to re- move all the diseased substance (d). 2437. For the extirpation of the parotid gland, it is most convenient to lay the patient upon a narrow table covered with a mattress, in such way on the healthy side, with the head a little raised, that the light may readily fall upon the swelling. If the tumour be not very large, the skin covering it not connected with it, and not diseased, an assistant fixes the swelling on each side with his fingers, thrusting it upwards at the same time, and rendering the skin tense; a longitudinal cut must then be made through the skin from the mastoid process to the angle of the jaw. If the swelling be larger, a crucial cut must be made ; and if the skin be attached and diseased, two semilunar cuts must be made and connected above and below, including the diseased skin. The m. pia-' tysma myoides is to be next cut through, and all the spouting vessels tied. The skin must now be separated from the surface of the whole swelling; the fibrous capsule opened sufficiently, and the tumour shelled out with the fingers or with the handle of the scalpel. The blade of the knife must be only used with the greatest caution, for the purpose of sepa* rating the firmer connexions. During the operation, an assistant must (a) Richter, Anfangsgrunde, vol. ivt par. (d) See also Berard, Maladies de la 401, 402. Glande parotide et de la region parotidienne< (6) Kyll, above cited. Operations, que ces Maladies rechmenti (c) Surgical Anatomy of the Head and Paris, 1841. Neck, p. 267. EXTIRPATION OF THE PAROTID GLAND. 525 constantly sprinkle cold water to keep the wound clear of blood, on which account, also, every spouting vessel should be immediately tied. In sarcoma, the substance of the swelling is often not of sufficient firmness to permit it being at once shelled out with the finger; it often tears, and the several parts must be removed piecemeal. When the fibrous cap- sule adheres to the gland, and cannot be freed, the separation of the tumour is exceedingly difficult, and requires the greatest caution. 2438. When on separating the swelling at its hinder part, a very firm connexion of it to the carotid artery running behind, or through its sub- stance, is perceived, a ligature may be applied round the tumour, after isolating as much as possible; or the trunk of the carotid artery may be tied, and the removal completed (a). When the tumour dips deeply, and its close connexion with the carotid artery is suspected, that vessel may be tied some weeks before the extirpation, which will then be per- formed with greater safety. In many tumours of the parotid, the ligature of the artery will indeed cause, by the diminution of the flow of blood, such decrease of the size of the swelling as to render its removal super- fluous (b). The previously tying the carotid artery, which was performed by Goodlad* (c), does not ensure against bleeding, which quickly follows, from the numerous anasto- moses and the quickly-restored collateral circulation. Thence Langenbeck's (d) advice, when, on account of the expansion of the vessels, or the firm connexion of the tumour, it is scarcely possible to avoid injuring the artery, first, to lay bare the artery, and include it in a ligature, which niustbe tightened if the vessel be injured, or the bleeding from its branches be great. I have, however, in one case, where the carotid was closely connected with the swelling, avoided wounding it in the total removal of the tumour, by which the vessel was so .perfectly exposed in the wound, that I could raige it with my fingers, and in case of having wounded it, could have easily applied a ligature. 2439. If, during the removal of the parotid gland, the carotid artery be wounded, it must be attempted to seize it with a hook, and tie it; but if this be not possible, the bleeding may, perhaps, be stanched by pressure, with the fingers, or by plugging, which, at least, has been done on one case of wounded facial carotid with success (e); or the wounded part of the artery may be compressed, and the common trunk of the carotid artery tied at once. 2440. After the extirpation is completed, the wound must be pro- perly brought together, the ends of the ligatures carried out in the shortest direction, the edges of the wound carefully closed with sticking" plaster, and the patient put to bed with his head a little raised, and inclined to the diseased side. The accidents which may occur after the operation, as severe inflammation, nervous symptoms, after bleeding, and the like, require the ordinary treatment. I have, up to the present time, performed eight extirpations of the parotid gland, without any untoward accident resulting from the operation. Cases of extirpation of the parotid gland are related by Prieger; in von Graefe und von Walther's Journal, vol. ii. p. 454; and in Rust's Magazin, vol. xix. p. 303. Berendts; in the same, vol. xiii. p. 159. Schmidt; in the same, p. 312. (a) Zang, Operationen, vol. ii. p. 618. (d) Biblro'hek, vol. i. p. 400. (6) Kyll, above cited, p. 18. (e) Larrey, Memoires de Chirurgie Mili. (c) Med.-Chir. Trans., vol. vii. p. 112. taire, vol. i. p. 309. 1816. Vol. iii.—45 526 CANCER OF THE BREAST. Weinhold; in Salzburger Medic.-Chirurg. Zeitung, vol. iv. p. 63. 1823. Beclard; in Archives Generales de Medecine, 1824, vol. iv. p. 62. Chelius ; in Heidelb. klin. Annalen, vol. ii. p. ii. Kirby, J., Additional Observations on the Treatment of certain severe forms of Haemorrhoidal Excrescence, &c. Dublin, 1825. 8vo. McClellan, G.; in American Medical Review and Journal. 1826. [Randolph, J. in Philadelphia Medical Examiner, vol. 2. 1839.— g. w. N.] D.—OF CANCER OF THE BREAST. Heister, L., Dissert, de optima Cancrum Mammarum exstirpandi Rations. Altorf., 1720. Tabor, (Praes. Serrurier,) Dissert, de Cancro Mammarum eumque novo ex- stirpandi methodo. Traj. ad Rhen., 1721. Vacher, Dissertation sur le Cancer du Sein. Besancon, 1740. Pallucci, N. J., Nouvelles Remarques sur la Lithotome, suivies, &c., et sur l'Amputations des Mammelles. Paris, 1750. 8vo. De Haupville, La Guerison du Cancer au Sein. Rouen, 1793. Adams, Observations on Cancerous Breast. London, 1803. Rcdtorffer, Abhandlung iiber die Operationsmethoden sengsperrter Leistenund Schenkelbriiche, vol. i. p. 122, vol. ii. p. 334. Bell, Charles, On the Varieties of Diseases comprehended under the name of Carcinoma Mammae; in Med.-Chir. Trans., vol. xii.-p. 713. Cooper, Astley, Lectures on Surgery, by Tyrrell, vol. ii. p. 175. ;----—--------, Illustrations of the Diseases of the Breast. London, 1829. 4to. Benedict, Bemerkungen iiber die Krankheiten der Brust und Achseldriisen. Breslau, 1825. Cumin, V., A general view of the Diseases of the Mamma, with cases of some of the more important affections of that gland; in Edinburgh Medical and Surgical Journal, vol. xxvii. p. 225. 1827. Brodie, Sir B. C, Lectures on Pathology and Surgery, above cited. [PArrisH, Jos* Observations on Affections of the Mammas, liable to be mistaken for Cancer, in North American Medical and Surgical Journal. vol. v. 1828. Parsons, Usher, On Cancer of the Breast, Boylston Prize Disserta- io ns. Boston, 1839. 8vo.—g. w. n.] 2441. The breast-gland is most Commonly affected with scirrhus; but in men this occurs very rarely. As to its origin and progress, all that has been said generally on canCer of glands applies; its development and course, however, present some differences. 2442. Most commonly a hard lump, round and moveable, arises with- out any previous cause, or after a blow, a squeeze, or the like ; as it grows it becomes irregular and knobby; a second and third lump is produced, which seem connected together by strings of hardened cellular tissue. As these several lumps enlarge, they become molten into each other ana with the gland, and spread especially towards the arm-pit. Passing, lancinating pains set in, which are not increased by pressure, and spread towards the shoulder, and over the arm. As the swelling increases, and the pain becomes more severe, they attack the skin, which assumes a channelled, scat-like appearance^ and the seba- ceous glands are often filled with a black substance; The skin becomes attached to the tumour, which rises considerably at one point, reddens, and thins; the veins swell, the nipple retracts, and instead of a promi- CANCER OF THE BREAST. 527 nence, exhibits a hollow. The skin at last breaks, and an ulcer forms, spreading in every direction, with hard, dusky red, glossy edges, and having a foul, sloughy bottom, though not with any very copious and offensively-smelling discharge ; the ulcer is rather a deep cleft, without any fungous excrescences. The glands in the arm-pit, on the collar- bone, and the neighbourhood, swell up, if they have not so previously. At this time, often even earlier, before the breast has broken, the patient complains of rheumatic pains in different parts, especially in the loins and thighs: nutrition is much affected ; the countenance assumes a peculiar bad, earthy appearance, the arm of the affected side swells, and can no longer be moved from the body, and death follows, under the symptoms of hectic consumption already described. This form of cancer of the breast is sometimes developed with a scirrhous inflammation, under which the whole breast swells ; or there has been previous long existent hardening, or a milk-knot, assumes the scirrhous degeneration. [Brodie, divides "scirrhous tumours of the breast into two classes; one where there is a conversion of the gland of the breast itself into the. scirrhous structure, there being no well-defined margin to it; the other, where there is a scirrhous tumour imbedded in what appears to be otherwise a healthy breast, as if it were altogether a new growth, there being a well-defined boundary to it." (p. 195.) The latter of these, the course of which is above described by Chelius, is the ordinary form of scirrhus; the former is comparatively rare, and, as. far as I have seen, does not pass into ulceration; but the whole gland, becomes converted into one hard stony mass, which retains the shape of a plump, well-formed breast. It, in general, grows rapidly, and the glands in the arm-pit soon become affected by the disease, and the patients powers are worn out by its malignant effect upon the con- stitution, although it does not ulcerate. I have, very recently, had two cases of this kind under my care, the one I have lost sight of, but the other is slowly sinking under the circumstances I have just mentioned. Brodie justly observes, that in such cases- "• the operation not only never succeeds in making a permanent cure, but rather hastens the progress of the disease. The patient dies within two or three years, and probably much sooner, from an effusion of fluid into the cavity of the pleura."- (p. 195.) I recollect having a case in which both breast* were affected by this general scirrhous enlargement, in adxlitiioo to which nearly the whole of the skin covering the front of the chest was closely set with scirrhous tubercles of varir ous size; but, in this case, both, breasts and skin ulcerated superficially, and the pa- tient died hectic, about three or four months- after the ulceration had taken place.— j. f. s.] 2443. Scirrhus of the breast frequently begins with a single lump at one particular part of the gland, and seems to stretch itself by a string- like process, towards the arm-pit. In the increasing enlargement, the whole gland of the breast is changed into a firm, elevated substance; its surface is granular, the skin bluish-red, blackish-red, with a bluish tinge. The tumour quickly adheres to the skin and underlying parts, and stretches towards the glands of the arm-pit, which rarely fail to swell. The ulcer has a dirty bottom*, red, hard, outturned edges, and hard knots are felt at various parts in and beneath the skin. The secretion of ichor in the sore is considerable, and very ill-smelling; bleedings frequently occur, and death follows, under the above-mentioned symptoms. 2444. Cancer of the breast not unfrequently is developed as skin- cancer. A lump, a wart, or a hard little mark appears at some one spot of the skin, which gradually reddens, and with lancinating pain, runs into ulceration. The ulcer spreads, with hard edges and bottom, after the 528 CANCER OF THE AREOLA. manner of skin-cancer, more on the surface, and little in depth ; it, how- ever, extends gradually to the glands. Swelling of the arm-pit glands follows much later than in glandular cancer. 2445. Cancer of the areola begins with knot-like swelling of its little glands, which ulcerate; the nipple itself is attacked and destroyed by ulceration. A dusky girdle in the skin surrounds the ulcerated parts; the affected breast is full, round, and elastic ; the neighbouring parts re- main unaltered. A fungous growth springs up from the ulcerated surface, which is reproduced as soon as destroyed. If these growths be left alone, they form a soft vascular fungus, and general disturbance follows, ac- companied with throbbing .pain in the breast; but if they be destroyed, the irritable condition of the breast ceases. Earlier or later symptoms appear, which show that the constitution has become affected; the pa- tient wastes, has a yellowish, earthy countenance, pains in the back and loins, and often dies, without the breast-gland being considerably affected by the disease. 2446. Cancer of the nipple begins with a round swelling at the root of the nipple, which i& not painful, but is very hard and irregular on its surface; as it enlarges.it becomes the seat of shooting, lancinating pains, which run from the swelling to the shoulder. The nipple ulcerates, is covered with a yellowish crust, which separates and forms afresh; more extensive ulceration follows, the nipple is destroyed, and a scirrhous sub- stance is laid bare. The scirrhus spreads widely round the nipple, the pain becomes more violent, but the diseased part is not tender to the touch ; a crust is no longer formed ; the ulcer secretes ichor, and some- times bleeds. The glands of the arm-pit swell, and the usual symptoms of hectic consumption close the scene. According to. Astley Cooper (a), a fungous regeneration of the nipple begins in the same way. Behind the nipple, and firmly connected with it, a round, less hard swelling than in scirrhus forms, which is slightly painful on pressure, but otherwise quite free from pain. Astley Cooper also mentions a swelling behind the nipple, which occupies the space of an inch, oceurfs commonly between seven and twelve years of age, is more frequent in boys than girls, mostly on one side, rarely on both, is tender, often painful when touched, moveable, and over which the skin is un- changed. This swelling is benignant, and yields to dispersing plasters, and the internal use of calomel and rhubarb, and the like. [Astley Cooper gives the following account of the development of the nipple in the foetus, and: of its. subsequent changes:—" In both male and female infants a gland exists, which is the nidus of the future nipple, over which the skin in puckered into a small projection. This glandular substance lies concealed under the skin until near the age of puberty, and then it gradually evolves and becomes converted into the nipple of the adult. In the male, the tubes through,which themilk of the infcnt passes become ligamentous cords in the nipple of the adult; and in the female, the similar tubes become the lactiferous ducts of the nipple. Thus it is that the nidus of the adult nipple is protected until the age of puberty. It is this structure, then, of the male and female nipple, prior to the age of puberty, at the time when the evolution of the nipple is commencing, which produces the swelling to which young people are subject, from the age of eight years to the period of puberty; for when the action is greater than the evolution requires, a hard inflammatory swelling is produced. ' It is in this structure that, in future years, the malignant areolar ox m mammillary tumour forms. Here the scirrhous tubercle commences, which de- stroys the nipple, and ultimately extinguishes the life of the patient. It is in this structure that, the fungus swelling above-mentioned is formed. The female is less ( and chronic cancer of the breast. Acute cancer begins as a hard lump, deeply seated in the breast, at first moveable, but in, one or two months adherent to the skin, which becomes discoloured. The hardness soon affects the whale breast, but only a single part projects much, is shiny, purple red', and' elastic, as if it contained fluid'. The pain is very violent and shooting, as in whitlow. The gland of the breast does not enlarge regularly, but in separate swell- ings; the glands of the skin seem, enlarged, the surface is beset with little white points, which become more distinct as the tumour becomes of a- deeper dusky-red: A trickling begins on the most prominent part, which may lead to the expectation, of suppuration, but this does not take place. The scirrhus quickly enlarges, with additional redness and increase of pain; the countenance- assumes a painful, anxious expression, and the skin a pale-yellow appearance ; and great feebleness and depression ensue. The larger lumps in the skin become.black, burst, discharge a little blood, and afterwards serum. Unawares the- surface sloughs to\ a great extent, and the breast is. deeply hollowed- by an irregular ulcer filled with black sloughs, its edges raised and beset with lumps, which burst, discharge, sltmgh, and form deep, foul ulcers. The ulceration spreads by the sloughing of these tubercles, and spread's incessantly ? far- ther and farther. That kind of breast-cancer is considered chronic, which, is1 dry and hard as cartilage; when it has acquired a certain size, it crumples to- gether, so that the swelling presents different clefts from the skin being drawn in and' wrinkled, in which the retracted* nipple is. com- pletely hidden. It is specially observed' in old, shrivelled women, with dry, tense fibre. Sometimes these scirrhi open by superficial ulcera- tion, which closes again with a scar (a). The pain is not very great, and the disease may exist for many years, without making any great progress. ["In many cases oft scirrhous. tumouTS of the breast, the skin," observes Brodie, "is drawn or tucked in, over the tumour, so as to produce the appearance of a dimple in it. Where this dimple in the skin exists, you may be almost sure that there is a scirrhous tumour in the breast beneath it, and on examination you will feef it,witb (a) Dictionn. des Sciences Mpdicales, vol. iii-,. p. 555. 45* 530 TUMOURS IN THE BREAST the finger. * * * But on what does this appearance depend 1 In a case which I dissected very carefully, I found a narrow process or elongation of the disease, perhaps half an inch in length, passing from the tumour through the adeps into the skin, and connecting the skin and the tumour to each other. In fact, the dimple indicates that the disease is not confined to the breast, but that the skin is already contaminated." (pp.. 197, 198.)] 2448. The interior, of scirrhus of the breast is the same as that al- ready generally mentioned. When cut into, it shows an exceedingly hard substance, from the midst of which white streaks radiate, between these and similar connecting streaks, by which a fan or net-like tissue is formed, having deposited between them a soft, lard-like substance ; in many instances the tumour forms a large, lardy mass, in wdiich the white streaks are fewer, even entirely wanting, and do not, as in the former instance, spread indefinitely beyond the boundary of the swell- ing (par. 2395.) The relation of these white streaks to the tumour is exceedingly important; in general they stretch much beyond the irre- gular hard lumps, which can be felt externally. The retraction of the nipple here affords an important character; it is produced by the streaks which originate in the centre of the lump, and spread between the milk-tubes of the nipple. In the same way these streaks stretch beyond the bounds of the gland into, the surrounding cellular tis- sue {a), 2449. Various tumours are developed in the breast, the distinction of which, from cancer is, in many instances, excessively difficult to the most,clever practitioner; and probably on such mistake inthe diagnosis rest those successful cases,,in which the dispersion of presumed scirrhus »has been effected by the use of internal and external remedies. Such tumours, are, «, Inflammatory affection, and painful swelling of the lym- phatic vessels, which run from the breast to the arm-pit; or swelling of the breast-gland itself, in consequence of chronic inflammation; or contin- ued swelling, after previous, inflammation and suppuration. /3, Milk knots or lumps, y, Scrofulous swellings. $, Herpetic and Psoric affec- tions, especially, about the nipple. ey Encysted tumours. ^Steatoma- tous degeneration, v, Medullary fungus. 6, Blood swellings, i, Hyper- trophy- , A careful examination of all the circumstances accompanying the origin, of such tumours can alone direct the practitioner in his diagnosis., 2450. Chronic inflammatory affection of the lymphatic vessels, or of the breast-gland,, is specially characterized by its being painful on pres- sure^.which is not the case-with scirrhus. Chronic abscesses in the breast sometimes form, exceedingly slowly, as hard swellings, in which only at a late period, fluctuation is indistinctly felt ; but the soft part is always surrounded to a tolerable ex-tent with a hard swelling. It is more readily mistaken as malignant, on account of the general health being always more or. less therewith affected; Irritating applications and plasters, opening'the swelling, poultices, and general treatment, which improves the constitution, effect the cure., Benignant hardening is commonly observed in young people, most frequently between puberty and the thirtieth, year* The swelling is usually superficial, feels as if a lobe of (a) Charles Bell, above cited, pi. i. iii. LIABLE TO BE CONFUSED WITH CANCER. 531 the gland were enlarged, as if several were united into one swelling. It is moveable, has no string-like processes towards the shoulder; there is no pain in the breast, shoulder, and arm ; no injuring of the general health ; no affection of the armpit glands ; and it is not so hard as scirrhus. The disease is in general sympathetic with the state of the womb, and occurs in unmarried or married women who continue unfruit- ful. Its occasional causes, with previous predisposition from uterine irritation, are often mechanical violence, blows, and the like. The swelling enlarges very slowly, never becomes large, remains long free from pain, and in many cases, only after, years, is accompanied with a stabbing, rheumatic pain. Dispersing remedies, repeated leeching, mercury, hemlock, iodine internally and externally, and means which regulate the functions of the womb and improve the general health, often diminish or entirely dissi- pate the tumour. But if not, if the swelling increase, its removal is indicated, and on account of its mobility, easy ; and it does not return. On examining such tumour, a number of lobes are observed, connected with thick cellular tissue, which, when cut through, look like cow's udder. After the cessation of menstruation, a swelling of this kind may become malignant; it may also disappear before that period, during pregnancy and suckling, although previously it has resisted all reme- dies. 2451. In very sensitive persons, between the ages of fifteen and twenty, when menstruation is suppressed, or irregular and scanty, and the whites are present, sometimes, if the breast have received a blow or# push, there may be very great tenderness to the touch, with or without swelling of one lobe of the breast-gland, and pain running from the breast to the shoulder and elbow, and not unfrequently to the hand and fingers. Previous to menstruation the swelling is greater, but after it of less size. The sensibility is often so great that restlessness and loss of sleep ensue; the weight of the breast is sometimes unbearable, even in bed, and vomiting occurs with the severity of the pain. The skin of the breast is unaltered, and without a trace of inflammation. Sometimes only a small portion, and at other times the greater part of the breast is affected, and sometimes both breasts may be attacked at once. The causes of this condition are always very irritable constitution and dis- turbed functions of the womb. Belladonna, opium, extract of hemlock, soap plaster, oiled silk, and the like, are employed locally, and in violent inflammation, leeches. Such internal remedies as diminish the excited sensibility, and.regu- late the functions of the womb, therefore, calomel and opium, and between whiles a mild aperient, aqua lauro-cerasi, or hemlock with rhubarb, should be given; afterwards strengthening remedies, especially the preparations of iron, with a corresponding dietetic regimen (a). [All these remedies and a vast many others are frequently employed without the least benefit, and patient and practitioner are equally tired of the complaint and of each other. Matrimony is the most agreeable and most certain cure for this most vexatious ailment, and should be gently hinted to the patients's friends.^-j. f. s.] (a) Astley Cooper, Lectures, 214. 532 TUMOURS IN THE BREAST 2452. Milk-knots ox lumps often present the same hardness as scirrhus. They always occur during pregnancy, or after delivery, from whatever cause can produce inflammation of the breast-gland, as, for instance, cold, vexation, fright, mechanical irritation, excoriation of the nipple, and the like. At first there are either symptoms of inflammation, which subside, or there is not any accompanying inconvenience. Besides these circumstances, milk-knots are characterized by their round smooth shape, and by their free mobility; they are generally in the middle of the breast, near the nipple, well defined, not surrounded by any hardened cellular tissue, and not connected by any strings to the neighbouring parts. They always diminish or disappear on the recurrence of the flow of milk ; they diminish in a second pregnancy, and generally lessen when menstruation comes on. Milk-knots have a malignant appearance in old women who have never been pregnant, if they occur after the cessation of menstruation, if sub- ject to mechanical injury, if connected with gout or other general dis- eases. The swelling is then harder and more irregular; the cellular tissue becomes hard around the knot and is connected by strings with the neighbouring parts; under such state scirrhous degeneration is al- ways to be presumed (a). To this place belong also those eases produced by suppression of ihe milk, or by rupture of the milk-tubes, and. extravasation of that fluid into the cellular tissue, which form fluctuating tumours, containing a very large quantity of milk. They generally begin soon after delivery, with a swelling, which fluctuates, without pre- vious symptoms of inflammation and suppuration, accompanied with a feel of painful distention, which increases when the child sucks.. The swelling arises at any one part of the breast from the nipple to the edge -r the cutaneous veins are enlarged ; out the part is not discoloured. Scarpa (b) saw such a tumour, which occurred during suckling, and from which, with a trocar, he drew off ten pints of pure milk. The introduction of a seton into the cavity, and its gradual?lessening by withdraw- ing some threads, favours the speedy diminution and complete closure of the cavity. In subsequent lyings in, the secretion of milk in the breast undergoes no alteration. [The disease just noticed is that named by Astley Cooper, the Lacteal or Lacti- ferous Siuelling; and though often containing a few spoonfuls of milk, rarely ac- quires a very considerable size. In 1839 I had a case five weeks after delivery, which was thought very remarkable, as more than a quart of rich, good milk was discharged by a puncture with a lancet. As I was fearful the aperture might close and the milk eollect again, a tent of lint was inserted in the wouhtf; but in the course of twelve or fourteen hours she was violently attacked with irritative fever, and when I saw her next day was exceedingly ill. The tent was removed, and im- mediately a quantity of very fetid air escaped, and about two ounces of stinking milk. She continued very unwell for three or four days, and afterwards the cavity slowly lessened, and she recovered., I should certainly-never again, in a like case, introduce any tent, and still less should I be disposed to pass a seton through, as recommended by Chelius; for the cavity having been deprived of its support by the discharge of its contents, is sufficiently disposed of itself to inflame, without further excitement. And indeed the surgeon has sufficient to do to keep the inflammation under; for I have seen, in two or three instances, when a small milk-swelling has been merely punctured, such inflammation eccur, that the skin covering it has quickly run into gangrene, and instead of one, three or four holes leading to the cavity, and subsequent troublesome sinuses, and a spoiled breast. The only treatment neces- sary, is a free puncture and soothing poultices, with purging, to lessen or get rid of the secretion of milk entirely, which keeps up irritation, and by its constant flow prevents the adhesion of. the walls of the cavity.—j. f. s.] (o) See par. 149,, and Benedict, above cited (b) Of uscuoli di Chkurgia, vol ii LIABLE TO BE CONFUSED WITH CANCER. 533 [Parker, in the N. Y. Med. Gazette for January 1842, has recorded a remarkable case of a similar kind.—g. w. n.] 2453. Scrofulous tumours in the breast may be easily taken for scirrhus, and even when they have gone into ulceration they greatly resemble can- cerous ulcers. The age of the patient, the general signs of scrofulous disease, and especially the circumstance that usually several, often a very great many, of these little swellings may be felt in the breast, should direct the practitioner. The treatment consists in the employment of anti-scrofulous and such remedies as improve the constitution, regularity of living, and the appli- cation of dispersing plasters and rubbing. 2454. Herpetic and psoric affections around the nipple can produce swelling of the nipple, and even of part of the breast-gland, and by the spreading of the ulceration, may cause considerable destruction. The origin bf the disease, the general state of health, and the above-mentioned {par. 153) mode oftreatment, are the foundation of the diagnosis. 2455. Encysted tumours in the cellular tissue of the gland of the breast are often very difficult to distinguish from scirrhus, especially when the cyst is very hard and firm. The marks of distinction are, the encysted tumour has no string-like connexions as scirrhus has, it is more defined, rounder, firm and elastic, or distinctly fluctuating, according to the thick- ness of the cyst. If the cyst be thin, and the tumour near the skin, the latter has a bluish colour. The general health remains undisturbed; the swelling is free from pain, unless there be any disposition to suppuration in the sac. When the fluid is emptied it is transparent as water, with a slightly-yellow colour. The walls of the cavity often consist of a pretty thick fibrous capsule, on the inner surface of which are red fungous ex- crescences of different size. Only large tumours of this kind need extirpation ; smaller ones, with a thin cyst, may be punctured, and by the introduction of a slip of linen, adhesive inflammation, and adhesion of the sac, or its throwing off by suppuration, may be effected (a). 2456. I consider that state of the breast-gland, commonly known as vesicular scirrhus, or carcinoma mamrne hydatides, as a steatomatous de- generation of the gland. The breast-gland, in such cases forms a very projecting tumour, the greater diameter of wdiich is not at the base, where it is connected with the chest, but at some distance from it. The form of this swelling is hot globular, but quadrangular, at some parts more, at others less prominent. The nipple is not drawn in, but pro- minent, and of the natural appearance. At some parts the swelling feels hard, at others tense and elastic, and even distinctly fluctuating. The veins on the surface are larger, the swelling moveable in every direction. It may acquire enormous size, and exist many years before it bursts or reaches the arm-pit glands. In one case which I saw in an unmarried person, thirty years old, neither one nor the other had happened. The swelling can easily be separated. The result of the operation is favour- able, if, in course of time, it have not passed into scirrhous degeneration. On examining the tumour, it is found to consist of large and small cavities, upon the unequal size of which the irregular shape of the tu- fa) Chelius ; in Heidelb. Medic. Annalen. vol. i. 534 TUMOURS IN THE BREAST mour depends, which are filled with serous, gelatinous, more or less bloody fluid, or with a lard-like substance, the walls of which are of different thickness, and even of a cartilaginous nature. Astley Cooper distinguishes several kinds of hydatid swellings of the breast. " The first species of this disease exists in the form of simple bags, which con- tain a serous fluid. I should call them cellulous hydatids ; and the symptoms which they produce are as follows :—The breast gradually swells, and in the be- ginning is entirely free from pain or tenderness ; it becomes hard, and no fluctua- tion can then be discovered in it; it continues slowly growing for months, and even for years, sometimes acquiring very considerable magnitude, the largest I have seen having weighed nine pounds; but, in other cases, although the bosom was quite filled with these bags, yet it never exceeded twice the size of the other breast. At first the swelling feels entirely solid, so that it bears a great resem- blance to a simple chronic enlargement of the breast; but, after a great length of time, a fluctuation can, at one part, be discovered in it, and then the breast begins to increase more quickly; and, in several parts, similar fluctuations can be detected. The cutaneous veins become varicose; but, although the breast is eminently en- larged, it still continues almost entirely free from pain ; but to this there are excep- tions. * * * At length one of the fluctuating portions of the breast slowly inflames, ulcerates, and discharges a large quantity of serum, or of a fluid having its general character, but of a consistence somewhat more glairy ; and the sac being emptied, and the external opening closed, if the fluid be entirely discharged,it is a longtime before it re-accumulates ; and sometimes the sides of the sac adhere, and the cyst ceases to secrete. In other instances I have known the swelling break and dis- charge a mucilaginous fluid mixed with serum ; and several of the cells in succes- sion, and at distant periods, pass through the ulcerative process, and form sinuses which are very difficult to heal. Excepting during the process of ulceration, the general health remains entirely undisturbed, and the person suffers so little either locally or constitutionally, that her friends do not discover her malady; and nothing would lead her to consent to an operation for its removal but the anxiety of mind and the apprehension which the idea of a cancer produces, and the great inconve- nience and distress which the weight of a large swelling occasions * * * It is found, upon a careful dissection, that the interstices of the glandular structure ifself, and the tendinous and cellular tissue connecting it, are, in a great measure, filled with fibrous matter, poured out by a peculiar species of chronic inflammation ; but, in some of the interstices, a bag is formed, into which a serous, or glairy, or sometimes a mucous fluid, is secreted, according to the degree of inflammation attending it; and this fluid, from its viscidity, and from the solid effusion which surrounds it, as well as from the cyst being a perfect bag, cannot escape into the surrounding tissue. * * * Vast numbers of these cysts are found to occupy each part of the breast, producing and supporting a continued but slow irritation, and occasioning an effusion of fibrous matter, by which the breast forms an im- mense tumour, consisting of solid and fluid matter. Within these bags of fluid, hydatids, hanging by small stalks * * * had a cellular tissue within them, in which a fluid was collected, which, although it produced the appearance of cells, or hydatids on the outside, within assumed the character of anasarcous swell- ings * * * This disease, in its first stage, resembles simple chronic inflam- mation, but may be distinguished from it by the absence of tenderness upon pres- sure, and the perfect health in which the patient remains, stamps it to be an entirely local disease. In the second stage, when it fluctuates, it is discriminated by observing several distinct seats of fluctuation, and by the absence of tenderness ; but the best criterion is the puncture of the bag, when the evacuation of a clear serum, instead of a purulent fluid, at once teaches the true nature of the disease. From a scirrhous tubercle it may be distinguished by the absence of those occasional acute and darting pains which accompany that malignant affection, by the preser- vation of health, and by the excessive hardness, which are concomitants of scirrhus. (p. 20-25.) A further peculiarity of this disease is, that it does not attack other parts by absorption, nor has Astlev Cooper seen it in both breasts. The treatment consists in puncturing it, if there be only one large cyst, and in its extirpation, when the whole breast is affected ; in doing which all the hardness must be removed to prevent the return of the complaint. LIABLE TO BE CONFUSED WITH CANCER. 535 Second-. "The breast was, in this case, enlarged, and, in the greater part, hard- ened, by the effusion of fibrin, (coagulable lymph,) in lobes, into the cellular tissue, but, in several parts, it contained bags of serum, and formed fluctuating cysts of various sizes. In each of these cells there hung a cluster of swellings, like polypi, supported by a small stalk; and the little pendulous projections appeared to float in the fluid which had been produced around them, in the different cysts. Many hyda- tids were found in a detached state, both in the fluid within the bags, and in the solid effusion in the breast; and taking the whole tumour, vast numbers of them had been formed in it. Their size varied, but the largest did not much exceed that of a barleycorn, the figure of which they assumed. In general they were of an oval form, or, I ought to say, oviform, as they were larger at one end than the other. "When opened, they were found to be composed of numerous lamellae, like the crystalline humour of the eye, or like the layers in the onion, which could be readily peeled from each other." (p. 40.) " It is doubtful if these structures are not of the nature of globular hydatids, and which have perished from the pressure of solid matter with which they are surrounded ; or, whether they are productions or secre- tions of the arteries of the part." (p. 41.) They are rare, and extirpation is the only remedy. Third. " The globular hydatid is contained in a cyst formed in the breast, by the adhesive process; for wherever it is deposited, it excites irritation, and becomes surrounded and encased by an effusion of fibrin which is highly vascular; and its internal and secreting surface is directly applied to that of the hydatid, and a slight moisture exists between them, they having no vascular connexion. In the breast I have only seen them exist singly, but, in other parts of the body, great numbers are found. It is a semi-diaphanous bag filled by a clear water, and it is uniformly smooth on its external surface. It has no opening or inlet, so that it must derive its nourishment by absorption from its external surface. It is composed of two coats; the external is of considerable density, and if any opaque body be placed behind it, it has the shining appearance of mother of pearl, and reflects the rays of light from its surface. It possesses a considerable share of elasticity, and rolls itself up when it is broken. This external layer is lined by a very delicate internal membrane, which appears to be its uterus ; for, from its interior, a multitude of small hydatids grow, which, at first, adhere to the membrane, but afterwards become de- tached, from its falling into the fluid which the hydatid contains. If, therefore, the fluid-contents of the hydatid be collected in a glass, an immense number of small hydatids will be discovered floating in them. * * * I am induced to believe them to be distinct animals: first, because they have an existence and growth of their own, having no vascular connexion with the part in which they are found, but being only encased and surrounded by a vascular and secreting cyst; -secondly, be- cause they have the power of producing upon their interior surface their own spe- cies. * * * When one of these hydatids is produced in the breast, an inflam- mation is excited by it, and a Wall of fibrin surrounds it; it feels hard, and from the small size of the hydatid, ^fluctuation cannot be discovered ; but as the hyda- tid grows, although the quantity of solid matter increases, yet as the fluid in the hydatid becomes more abundant, a fluctuation in the centre of the tumour may be ultimately perceived. Sometimes, when the hydatid has considerably enlarged, it produces a suppurative inflammation ; and when the matter is discharged, either by the lancet, or by ulceration, the hydated escapes at the opening." (p. 47-49.) Brodie (a) appears to me to have described Astley Cooper's former two kinds of hydatid tumours under the name of Serocysiic Tumour of the Female Breast. With Cooper, he agrees that " it does not contaminate either the skin or the lym- phatic glands; it is not complicated with any correspondent disease of the viscera, and all the experience which I have had justifies the conclusion, that if care be taken that no portion of the breast be allowed to remain, we need not be apprehen- sive of its recurrence, (p. 154.) It is undoubtedly not malignant in the proper ac- ceptation of the term. It may go on to inflammation and ulceration, and the ulcer may spread, and slough, and bleed, but it does not contaminate the constitution. Still I am not prepared to say that it may not, under certain circumstances, and in peculiar constitutions, assume a malignant character; this being no more than may happen to almost any morbid growth." (p. 156.)] (a) Lectures illustrative of various subjects in Pathology and Surgery. 536 TREATMENT OF HYPERTROPHY The treatment consists in cutting into and cleaning the cyst, or in the introduc- tion of a seton. This latter form only seems to admit of being held as a peculiar state of dis- ease, as in the others as well as in scirrhous degeneration, the formation of larger and smaller cysts and sacs must be considered as accidental, and resulting from the distention of certain cells. 2457. Medullary fungus is developed either in the breast-gland itself, or between it and the armpit, as a roundish swelling of which the hard- ness is not so great as in scirrhus, and the surface is more regular. In its further growth the tumour softens ; the skin covering it, is at first natural, but afterwards becomes livid ; the veins swell considerably; the surface of the skin assumes an inflamed appearance, and the swelling shows evident fluctuation. The pain is less than in scirrhus; the armpit- glands swell more rarely; the nipple is not drawn in, and the skin has not the puckered appearance as if covered with scars. When the tumour opens, it discharges a bloody fluid ; a fungus soon sprouts from the opening and bleeds readily ; a stinking ichor is secreted in great quantity. Its progress and reaction upon the whole body is generally quicker than in cancer. This medullary fungus shows itself at all times of life, but it is most common after the thirtieth year. 2458. The blood-swelling of the female breast begins with a gradual and moderate tumour of the breast, which in delicate women is not unlike the distention and fullness which occur during menstruation, though greater, and attended with more uneasy and continued sensibility. By degrees a superficial hardness is noticed ; the disease, however, rarely remains in this state more than a few days ; its extent gradually increases till all the neighbouring parts have a feel of softness. In the midst soon arises an isolated, small, but not hard swelling, nearly at the part where at first the breast, on slight pressure, with the finger, was more sensible. This first stage has an indefinite period, two, three, six, or twelve months, during which the symptoms, after subsiding, occasionally again seem to re-commence. The swelling feels like a small conical or egg-shaped body, which is not so distinct from the surrounding parts that it can be easily twisted by the fingers ; it, however, is so loosely connected that it can be pushed from side to side. The skin is neither red nor warm; the parts immediately about the swelling suffer dull pain, and sometimes an actual numbness. The tumour is somewhat superficial, and at the same time causes a feel as if there were some soft body between it and the skin, which can be moved about upon it. The duration of this second stage also varies; the increase of the swelling may be for years scarcely perceptible, but circumstances may operate which may effect this in months. Sometimes the tumour enlarges, but after a time resumes its previous condition ; and whilst growing, it always retains a rounded form. A diseased condition of the veins is probably the foundation of this complaint, in consequence of which, either from repeated congestion, or from the effect of external violence, there is an outpouring of blood into the cellular tissue, and a pretty firm tumour is formed. In its treatment the general state of the health must be carefully attended to. In the first stages, leeches, dispersing applications and purgatives must be employed; in the second, moderate pressure, and HYPERTROPHY OF THE FEMALE BREAST. 537 careful evacuation of the blood by puncture. Shelling out the sac and removal of the breast are usually superfluous {a.) In consequence of a considerable determination of blood to the breast in girls under twenty-two years of age, there has been noticed, a few days previous to menstruation, a vibex or a broad streak, as of extravasated blood, with great sensi- bility and pain, which gradually spreads over the arm to the fingers. Sometimes this ecchymosis disappears a week after menstruation, but recurs more or less regu- larly with it. In severe cases it remains till the next menstruation. It is not dangerous, but indicates the necessity of regulating the functions of the womb. The best dispersive is the application of acetated liquor of ammonia with spirits of wine (Astley Cooper.) Here, also, must be noticed, the weeping of a yellowish-white or blood fluid from the nipple, which sometimes appears only at the menstrual period, but at other times continues still longer, accompanied with swelling of the whole breast, sometimes also with several swellings in the breast-gland, and sometimes with dragging pains. I have hitherto seen it only in unfruitful women, or in those who are childless, towards the cessation of menstruation. With regular living and abstinence from all sexual excitement I have noticed this discharge, which had continued after the menses had ceased, gradually subside. Only in a single^case, after the quick sub- sidence of the discharge from the nipple, was a scirrhous swelling of the breast- gland produced. Pigne observed a like case in a man fifty years old, in whom from four years of age there had been regularly every month a discharge of bloody, watery fluid from the nipple, which, was more Copious in spring and autumn. After sudden subsidence of this discharge, a hard regular tumour as large as a pigeon's egg was produced, which soon became the seat of lancinating pain. The patient was well for six months after the operation; but then the scar burst, a can- cerous ulcer formed with swelling of the armpit-glands, and death ensued after some months. On dissection all the bones were found softened, very flexible, and easily cut through with the knife as is often observed in cancerous dyscrasy. 2459. Hypertrophy of the female breast is characterized by a regular and painless increase of substance, which is produced either suddenly at the period of development, or more slowly at a later period. Some- times only one, at other times both breasts are affected at once, and may attain very considerable size and wTeight, from ten to twelve pounds. At first there appears, without any change of colour in the skin, great tension, but afterwards with Considerable increase of size, a soft con- dition, and only when the finger is pressed in deeply, are the enlarged and hardened acini of the breast-gland felt. When this hypertrophy occurs in later years, it may exist for a long while without any general affection and without any other inconvenience than its weight, as I have in some cases observed, in otherwise healthy and blooming women. If it occur at the period of development, it generally begins in the right breast, rarely in both at once, with a feel of prickling or increased sensi- bility ; menstruation is either wanting entirely, or sparing, and irregular; but every time it appears, the above-mentioned symptoms increase, and the breast suddenly enlarges. Frequently the voice at the same time undergoes some alteration, it becomes rough and hoarse; this continues often only a few days during menstruation, subsides and returns without any cause being discovered. In gradual enlargement of the breast, the nipple becomes flatter and broader, its areola larger; the swelling, at (a) Monro, A., M.D., Histories of Collec servationes Chirurgiccs, pi. i.—Roddmann tionsof bloody lymph in Cancerous Breasts; J.; in Edin. Med. and Surg. Journal, vol in Edinburgh Medical Essays and Ubserva. xxx. p. 1. 1828. tions, vol. v. p. 337. 1747.—Richter, Ob. Vol. hi.—46 538 TREATMENT OF HYPERTROPHY OF THE FEMALE BREAST. first rather tense, softens, and only when the finger is pressed in deeply are the enlarged and hardened acini felt. When the swelling has acquired considerable size, the veins of the skin swell in consequence of which it has a bluish appearance, although the colour of the skin itself is unaltered. The swelling now either remains stationary, and may con- tinue a long while, even during the whole life, without any further influence on the general health; or there may occur in the hypertrophic organ further connexions, outpourings, encysted tumours and the like • Or there may be with symptoms of affection of the air-passages and lungs, dry cough, sometimes frothy, sometimes streaked with blood, difficult breathing, hydrothorax, hectic fever and death. 2460. On anatomical examination of hypertrophic breast-gland, there is found besides the increase of substance and enlargement of some acini, no other variation from the natural structure. More fat is collected in the loose cellular tissue; the arteries are unchanged ; the nerves, indeed, not smaller and thinner, though backward in comparison with the size of the breast-gland ; the veins are always much distended, and their struc- ture changed, and the milk-vessels swollen and enlarged. 2461. The cause of this hypertrophy during the period of development is always the sympathetic relation of the breast with the internal gene- rative organs, which may be increased by various causes, as the use of irritating exciting food and drink, irritation of the breast by feeling it, by libidinous excitement, by washing and rubbing with irritating substances 2nd the like. At a later period of life, however, I have noticed this hypertrophy in women, in whom the functions of the womb were quite regular, and no further cause could be discovered. 2462. The object of the treatment is either the diminution of the excessive formative activity, or the removal of the gland with the knife. The former mode oftreatment, which can only have a satisfactory result, in the beginning of the disease, when at the time of menstruation, a prickling feel in the breast, or its increase of bulk occurs, requires, especially in full-blooded persons, and congestion of the breasts, bleeding from the feet, and internally, nitre with camphor, vegetable and spare diet, and the avoidance of those influences which may excite the living activity of the ftffected part. With greater swelling, iodine, burnt sponge with digitalis, rubbing in ointments of iodide of potash or of mercury, and the application of cloths smeared with camphor, leeching from time to time, and continued pressure. After three or four weeks a pause may be made, when the patient may live a little better, and then the previous treatment may be resumed. The internal use of extract of hemlock in increasing doses, and the application of camphorated hemlock plasters, I have found, after previous antiphlogistic treatment, do good service. On the failure of these means, Fwgerhuth (a) has seen great effect from exciting the breast-gland to action by constant application of a milk-glass, or of a cupping glass, as although the swelling is thereby at first increased, the dragging and tense feel subsides, and in the course of some weeks the enlargement ceases with the appearance of secretion of the milk. If, in spite of this treatment, the enlargement of the breast proceeds, and if the constitution be affected, the removal of the breast is the only (a) Ueber Hypertrophy der Briiste; in Hamburger Zeitschrift, vol. rii. p. 159. 1836. PROGNOSIS OF SCIRRHOUS BREAST. 539 remedy, and if the patient will not submit to it, the breast must be sup- ported with a suspender, attending at the same time to the secretions and excretions, moderate diet, and exercise in the open air. [Huston, S. C, On Hypertrophy of the Mammae in Amer. Journ. of the Med. Sciences, vol. xiv. 1834.—g. w. n.] 2463. That which has been already mentioned generally, applies to the aetiology of scirrhus of the breast. Its causes may be internal or external. In many instances it occurs without any manifest cause, and the origin of the irritation of the breast may, perhaps, in many cases, be founded on the sympathetic relations existing between the breast and the womb. Hence scirrhus most commonly appears at the period of decrepi- tude, in unfruitful women, in whom the functions of the womb have never been properly performed; hence sometimes hardening of the breast remains for a long while without any inconvenience till the time when the menstrual function begins to be disturbed, on which the passage into ulceration quickly takes place. 2464. The prognosis of scirrhus of the breast rests on the general cir- cumstances above mentioned. The only remedy is its removal, and the earlier this is done, the better the constitution, and if menstruation be still regular, the more favourable may the result be expected to be. Where the scirrhus is already in the state of concealed cancer, the nipple much drawn in, the skin less free and moveable, the general health affected, menstruation irregular or entirely ceased, the result of the ope- ration is indeed doubly doubtful; it is, however, the only remedy to prevent certain breaking. If the scirrhus be already ulcerated, if it be immoveably connected with all the pectoral muscles, if there be also hardening of other organs, no cure is indeed to be expected from the operation; it may, however, in so far, in such case, be considered as a palliative, as the patient is at least free from the great inconvenience attendant on the destruction of a scirrhous tumour by ulceration. I have not noticed a quicker progress of the disease after the operation, but on the contrary, considerable relief for a long while. The operation is easy when there is only a single moveable knot to be taken away, but more difficult when the swollen armpit-glands have to be removed, which also render the prognosis more unfavourable. It is self-evident that the gene- ral circumstances already mentioned, which contraindicate the operation for cancer apply here also. It m,ust not be overlooked in deciding upon the removal of a scirrhous breast, that in the cases where cancer has been very slowly developed and accompanied with no great pain, that after the operation the ulceration again proceeds even quickly, and thus the operation only hastens the fatal result. Before the operation is performed, an issue should be made in the arm of the affected side, and allowed to discharge properly, and the generally irregular state of the alimentary canal should be put right. [The question as to the propriety of removing a scirrhous breast is most im- portant; and one about which there has been great difference of opinion. Brodir states that "the late Mr. Cline, sen., and Sir Everard Home, both men of great experience and sound judgment, would scarcely ever consent to the removal of a scirrhous tumour of the breast under any circumstances; whereas, he has known other very experienced surgeons who were in favour of an operation, even in the great majority of cases. And, not only has there been this difference of opinion between 540 PROGNOSIS OF SCIRRHOUS BREAST. different individuals, but he has known the opinion of the same individual to differ at different periods."—(p. 193.) Proof sufficient this to show the importance of reviewing carefully this point of practice. The general recurrence of cancer after the operation, as more especially shown by Leroy d'Etiolle's statistics, has been already mentioned (par. 2408 note;) let us now see how it applies to cancer in the breast. Having a vague recollection of hearing Sir Astley Cooper mention the very small number of cases in which cancer of the breast did not recur after the numerous operations he had performed for its extirpation, I took the opportunity of inquiring of my friend Bransby Cooper, whether he could afford me any positive information of his uncle's experience on this point. His reply is:—"I cannot find anything relating to the query you put to me, respecting the statistics of his (Sir Astley's) success, but have a recollection of something like your own impression, that he acknowledged not more than nine or ten out of the hundred extirpations he had per- formed did not return, and generally within three years at farthest." Brodie says:—"In the larger proportion of cases in which the operation is per- formed, the patient is not alive two or three years afterwards ; and in a great many cases, instead of the operation stopping the disease, it actually seems to hasten its progress." (p. 192.) This statement fully bears out that of Leroy d'Etiolles. Brodie then at length proceeds to mention the circumstances under which scirrhous tumours are not likely to be cured by operation, and in which, therefore, it is im- proper; and these are briefly pointed out by his enumeration of the conditions suit- able for the operation, in his reply to the question, "What are the cases, then, in which the removal of the breast is proper?" " Where, on careful examination, no appearance of disease can be detected in the skin ; where there is no dimple in the skin over the tumour ; where there is no dis- eased gland in the axilla; where there is no sign of internal mischief; where there is no adhesion of the breast to the parts below; and where the patient is not very much advanced in life ;—in a case where this fortunate combination of circumstances exists, we may presume that there is a reasonable chance of an operation being suc- cessful. Still, I must not be misunderstood, as saying, that in every one of such cases there will be a permanent cure; nor do I say more than this, that the chance of a cure is sufficient to warrant you in recommending the patient to submit to an operation; and that I have the satisfaction of knowing several persons on whom I have performed the operation under these circumstances, who are now alive and w:ell, and who, otherwise, would certainly have been dead long ago." (pp. 199,200.) He then mentions two cases; in the one, the patient was operated on fourteen, and the other thirteen years since, and both are at present (1845) in good health. Bransby Cooper informs me, that he had " removed the undoubted-malignant breast of Mrs.------, and it was eleven years and a half before it returned in the cicatrix, and then killed her." In the summer of 1836, I removed a scirrhous tumour in the breast from a woman of sixty-one years of age, its size that of a small bean, which had been discovered only two months. In this case there has been no recurrence of the disease, and the woman has been and still is in good health. The most remarkable case, however, of which I am aware is one operated on by my friend Callaway, and this woman was not destroyed by the disease till twenty- two years after the operation. Notwithstanding these few favourable instances, surgeons should be cautious in urging a patient to submit to an operation for a scirrhous tumour, and still less, when it has become a cancerous sore, and the neighbouring glands in either case have become affected. He cannot promise a cure by the operation; nor can he even say, that the patient's condition will not be made worse. I have often heard it stated, that though the operation will not cure, it will put off the evil day, and retard the ulcerative process; but this I do not believe, for I have known many instances to the contrary. The only thing that an operation can do, is temporary palliation, if the patient be subject to severe shooting, stabbing pain, which is not indeed very commonly the case, unless the disease be worried by local attempts to cure. The practitioner ought, when consulted under these circumstances, to break to the patient cautiously the nature of her complaint; should inform her that all which can be done by operation is at best merely palliative; and should leave her to decide upon whether she will yield herself to the operation, knowing the risk and the slender hope connected with it; rather than urge her to an operation which is without doubt, EXTIRPATION OF SCIRRHOUS BREAST. 541 as regards scirrhous swellings, the most unsatisfactory in the whole course of surgical practice.—j. f. s.] 2465. The removal of a scirrhous breast is effected either by extirpation, leaving, however, a sufficient quantity of skin to coyer the wound, or by amputation, that is, taking off the tumour at its base. 2466. Extirpation of the scirrhous breast is generally performed in the same way as the removal of an encysted tumour. The patient lies upon a table (1), or is seated in a chair, and whilst an assistant makes the skin tight, the operator makes two cuts extending from the breast-bone towards the shoulder, which should include the nipple and a large portion of skin, so that the two folds of skin should be sufficient after the opera- tion to cover the wound. The lower flap-of skin must be separated from the swelling, which is then to be taken hold of with the fingers or with a hook, lifted up, separated from the pectoral muscle, and afterwards from the upper flap from within outwards,, or from without inwards ; and wTater is to be sprinkled on the wound to keep it clear of blood. The bleeding vessels must, during the operation, be compressed by the fingers of the assistants, and after its completion, tied (2). The wound" must then be cleansed, carefully examined, and every diseased* part seized1 with the hook or forceps, and removed. The edges of the wound* are to be brought into perfect contact, and* fastened with sticking plaster, lint and compresses applied, and' the whole supported with a broad breast- bandage (3). The after treatment is according to the ordinary rules. [(1), The horizontal posture on:a table is preferable to sitting in a chair, because the patient can be more completely steadied, and also because there is much less chance of her fainting; for if, as sometimes happens, there be a large escape of blood, she faints so completely that the-operation must be delayed till she be restored. (2) If the scirrhous tumour involve the whole breast, and be very large, with full swelling veins, the operator must carefully look to the bleeding, and I think, tie at once either arteries or veins, which may pour freely, as in a very few minutes very serious and even fatal consequences may ensue; ofsuch a case I have a very painful recollection. I operated many years since upon an, elderly woman who had an enormously large scirrhous breast, and the veins of the skincovering.it were much swollen. Before the operation I feared there would be severe bleeding, and pro- posed' taking up the vessels as they were cut through during the course of the ope- ration, but this was overruled, and pressure with the fingers was-determined on, leaving the vessels to be tied after the operation. The bleeding was.terrific, and poured from so many veins.that it was not possible to grasp and.close them. The operation was not tedious, but I had hardly removed the swelling before the woman had died. A lesson not to be forgotten. (3) The less dressing the wound of the operation is subjected to the better; and it is certainly advantageous not to dress it immediately, for many little vessels which have ceased bleeding whilst exposed, and the patient is faintish, burst forth, often furiously, when the wound has been brought-together at once, and the patient gets warm and has the circulation restored, so that in the course of two or three hours, the whole ca.vity formed by the removal,of the breast, becomes distended with blood, and then the bleeding, makes its way through the plaster,,the patient is drenched in Wood, and instances have not been wanting in which her life has been lost in consequence., It is, therefore, better always to leave the wound'.open for a few hours, and lightly covered with merely a piece of linen, not lint, the fl'uff of which sticks to the wound, and cannot be got off without great difficulty, and indeed not then even completely, so that it prevents adhesion, and is only thrown ofi by the establishment of suppuration, which is not desired. Neither is the linen to be jammed and kneaded into every crack and cranny of the wound, and left there for hours, as if it be, the adhesive matter soon- glues it fast to the surface of the wound, and it can only be removed with great difficulty and pain to the patient, which is 542 AMPUTATION OF SCIRRHOUS BREAST. quite unnecessary. The linen is merely to be moistened with cold water, laid lightly over the wound, and replaced every ten minutes, or thereabouts, till the bleeding ceases. Any vessels which bleed, must be taken up as they are found, and after four or six hours, the edges of the wound must be gently drawn together, and retained in place by long strips of plaster, which should be half an inch apart, to allow the escape of the serum as it separates. A wet piece of linen may also be advantageously laid over the strapping, and repeatedly changed, which quiets the arterial action of the part, and keeps down inflammation. I never put on compress or bandage at the first dressing. With this mode of treatment, the wound rarely requires dressing before the fourth or fifth day, when a poultice should be applied for a few hours, to soften the strapping, and facilitate its removal. If soon after the operation the breast become tender and inflamed, a light bread and water poultice, without disturbing the dressing, is very grateful to the patient's feelings, and encourages suppuration at any parts disposed to that process, after which the inflam- mation quickly subsides. The principal use of a roller round the chest is to keep the skin close to the muscle beneath, so as to prevent the pus bagging, if the two surfaces have not completely united.; and under such circumstances, compresses may also be requisite at any period of the healing of the wound. But as a general rule, the lighter and less the dressing is, the better the case proceeds.—j. f. s.] 2467. In amputation of the breast, the skin must be divided by two cuts carried around the base of the tumour, which must be detached from the pectoral muscle from below upwards. This method is at least more sure to save the skin than removing the swelling, by one or more strokes with art amputating-knife, or than by the method recommended by Galenzovsky, of drawing the knife upwards (a). When the vessels have been tied, the wound must be filled with lint, and this fastened with sticking plaster and a bandage. When the granulations have risen equally over the wound, its edges must be attempted to be drawn together with sticking plaster, to favour their scarring. The wound should be dressed only with lint, without, digestive or other applications, and only towards the end of the treatment, with narcotico-balsamic oint- ment. Benedict (b) considers moistening the wound with tincture of opium, and a dressing of opium ointment, as the best means to prevent return of the disease. Experienae, however, speaks as little in favour of this practice as for the trans- plantation of a flap of skin, recommended by others. [I do not think amputation is to be preferred to extirpation of the scirrhous breast, unless it be so large, or the skin so extensively diseased, that it cannot be avoided. But I have seen amputation occasionally performed, and it is remarkable how quickly and how completely a large wround thus made fills and draws together; but what the issue of-such, cases has been I do not know.-r-j. f. s.] 2468. Opinions vary as to the preference of extirpation or amputation, as well, also, as to healing the wound by quick union, or by suppuration and granulation. Extirpation and quick union are generally held to be the most preferable mode of treatment, because the cure is thereby effected most quickly, a regular scar is formed, and the wound is not so long subject to irritation as in suppuration, which, under existing disposition;,, more readily leads to scirrhous degeneration. But it is supposed that, as the ligamentous white strings so commonly extend in the cellular tissue beneath the skin, beyond the bounds of the tumour, and even are still left by the most cautious extirpation, amputation must have the preference, at least when the skin, though only at some (a) von Graefe's und von Walther's Journal, vol., xii. p. 606. (fr) Above cited. CANCER OF THE PENIS. 543 spots, is not quite moveable, or even degenerated, and the nipple much drawn in. That recurrence of the disease is more ready from the irrita- tion accompanying the cure of the wound by suppuration, I must from experience deny: as I have certainly seen, by this plan of treatment, with simple and proper management of the wound, more successful results than after extirpation and quick union. After the removal of the scirrhous breast, the surface should always be carefully examined and considered, whether it be covered with a layer of healthy cellular tissue, or whether there be any trace of the divided liga- mentous strings remaining, under which circumstance the still remaining parts must be taken away with the greatest care. 2469. Swollen armpit-glands, if superficial and moveable, may some- times be removed; for which purpose a hook is thrust into the outer corneg of the wound, and the gland drawn forth. This, however, is never advisable; it is best to lengthen the cut from the outer corner of the wound into the armpit, because there are, in most cases, stringy hardenings along the edge, and even under the great pectoral muscle, which must be removed. The vessels are to be tied as the gland is shelled out. If the seat of the gland be so deep, that it cannot be extirpated without danger of wounding the vessels, the gland must be separated as near as possible to its base, pulled forcibly down, and a ligature put around it. When the armpit-glands are swollen they must be removed, although in many cases the swelling is benignant, and seems to be merely sympathetic (a). 2470. Separate and moveable lumps in the breast may be managed with a simple cut, and shelled out. Though most practitioners give the better advice of removing the whole breast. If the cancerous degeneration have extended to the ribs ani: pleura, the diseased parts should, according to Richeran (b), be cut out. 2471. If the wound do not close perfectly, if several parts have an ill appearance, or if a scirrhous swelling spring afresh from the scar, it must either be destroyed by caustic, or stilt better, be removed with the knife. When the wound has scarred, it should be covered with a soft rabbit's skin, the patients mode of living attended to, and issues kept up. E.—OF CANCER OF THE PENIS. Pallucci, N. J., Nouvelles Remarques sur la Lithotomie suivies de plusieurs Observations sur la Separation du Penis, &c, Paris, 1750. 8vo. Loder; in his Chirurgisch-Medicinische Beobachtungen, p. 79. Richter, Dissertatio de optima, membrnm virile amputandi methodo. Konigs- berg. 1804. Thaut, Abhandlung uber den gesunden und kranken Zustand des mannlichen Gliedes. Aus dem Latein. Mit Zusatzen, von Eyerel. Wien, 1815. Siebold; in his Chirurg. Beobachtungen, vol. iii. p. 349. Schreger; in his Chirurgische Versuche, vol. i. p. 212. Biener, Dissertatio de Exstirpatione Penis per ligaturam. Lipsiae, 1816. Dzondi; in Beitrage zur Vollkommung der Heilkunde, vol. i. Halle, 1815. (a) Klein, Chirurgische Beobachtungen, sur le danger de la Resection des C6tes et p. 263. de l'Excision de la Pleura dans les Mala- (b) Histoire d'unc Resection des C6tes et diesCancereuses. Paris,, 1818. de la Pleura. Paris, 1818.—Nicon, Dissert. 544 CANCER OF THE PENIS. 2472. Cancer of the Penis begins almost always on the glans or on the prepuce, in a hard knot or wart, generally at first unaccompanied with pain, but when it is irritated, or of its own accord it becomes painful, and runs into ulceration, which is accompanied with an ichorous, stinking discharge, and with a hard swelling of the neighbouring parts. The urethra is often destroyed at different parts, and the urine flows from many openings; the neighbouring glands in the groins are affected. Persons who have the prepuce long, and a collection of cheesy matter upon the glans from want of cleanliness, are most frequently attacked with cancerous degeneration; and the prepuce inflames, excoriates, swells, thickens, and narrows still more. Ulceration increases on account of the difficulty in passing the water; the aperture of the prepuce some- times closes completely, and the urine flows through several openings in the destroyed prepuce, which may often be degenerated to a great extent before the disease has attacked the glans. In aged persons cancer most commonly begins, in the way just mentioned, upon the prepuce, because, by the retraction and wasting of the penis, the orifice of the prepuce is more influenced by the discharge of the urine. The diagnosis of cancer of the penis requires the greater care, as not unfrequently syphilitic ulcers assume a cancerous appearance, with fungous growths, hard out-turned edges, and lancinating pains, accom- panied with swelling of the neighbouring glands; in which case only the ordinary mercurial treatment, in connexion with sedative remedies, is requisite {a). 2473. When the disease has arisen from a narrow prepuce and want of cleanliness, in the early period further destruction may be prevented by purifying injections, by softening poultices, by drawing off the urine with a catheter constantly worn, or by the operation for phimosis (b) If the warty excrescence have a neck, it may sometimes be easily removed from the base. Sometimes the cancer only attacks the prepuce, without the glans itself being affected, under which circumstance the removal of the prepuce is sufficient. If the cancer be already on the glans, and spread further, amputation of the penis is the only remedy. This operation is in general more successful than the removal of cancer from other parts, but an important point is, that the testicles, the skin about the pubes, and the ingiunal glands should be free from hardening. [The observations I have made as to the recurrence of this disease certainly do not confirm Chelius's statement of the successful result of amputation of the gent's, even in the early stage, as the disease almost invariably returns. I remember one very remarkable case, in which, under favourable circumstances, the younger Cline removed the whole.penis as low down as the membranous part; by detaching it as far as possible from the pubic bones in front of the scrotum, and then making a cut into the perinaeum, he turned the penis down through it, and completely scraped off the crura to their very origins from the bones, and removed them and the bulb, leaving only the membranous part of the penis ; but the wound in a few weeks took on a cancerous disposition, spread quickly, and destroyed the patient probably quicker than if he had been left alone.—j. f. -s.] 2474. Amputation of the penis is performed either by the knife or by a ligature. Previous to the operation' the glans should be carefully exa- mined, to ascertain whether the prepuce, alone be affected. As much as [a) See my Bericht uber die Einrichtung der chirurg, Klinik, u. s. w. (b) Earle; in Med.-Chir. Trans., vol. xii. p. 289. AMPUTATION OF THE PENIS. 545 possible of the penis should always be preserved, as thereby the discharge of the urine is rendered easy, and even connexion itself is still possible. 2175. Amputation of the penis by the knife varies, as it is performed near the hinder part of the glans, or in the middle, or at the root of the penis. 2476. In amputation of the glans alone or near its hind part, an assistant grasps the penis, behind the diseased part, with his thumb and finger, and draws the skin back. The operator then takes hold of the fore part of the penis, which should be wrapped in linen, draws it a little towards him and cuts it off' at a stroke with a small amputating knife through the healthy part. The bleeding vessels are then to be tied, and the weeping of the blood from the spongy bodies stanched with cold water, and after the wound has been cleansed, a silver catheter or piece of elastic catheter is to be introduced into the urethra, and the edges of the wound closed from above downwards with sticking plaster. Some wads of lint are then to be put over it, and a Maltese cross bandage fastened over it with a narrow bandage. The tube in the urethra must be fixed by tapes through its eyes. 2477. If the penis be amputated in the middle, the assistant and the operator grasp it behind and before the part where it is to be cut off', without drawing the skin either backwards or forwards. The rest of the proceeding is as in the former case. 2478. In removing the penis near the pubic bones, Schreger has recom- mended the cut to be made with repeated strokes, to prevent the retrac- tion of the stump, and render the application of the ligatures more easy. An assistant presses up the bulb from the perineum forwards towards the pubic angle, and then, the operator having first drawn the penis and the skin forwards, divides the skin upon the dorsum penis and ties the dorsal arteries ; after malting the second cut, he proceeds in the same way with cavernous arteries of the penis, and after the third, with the cavernous arteries of the urethra, and the bleeding having been thus stanched, the remainder of the penis must be cut through. The dressing is to be made as already directed. If the bleeding from the spongy bodies can- not be stopped by sprinkling with cold water, the wound must be sprinkled with some styptic powder, covered with lint, and this fixed as already directed. Langenbeck (a) proposes to prevent the retraction of the penis in the following way: he cuts through the dorsum penis so deeply into the cavernous bodies, that he can see their white edge and the septum ; a loop is then drawn through both, and the penis completely cut through. The ligature serves to keep the stump steady, and to draw it forwards. To prevent the retraction and drawing together of the urethra, Barthelemy (b) advises introducing an elastic catheter, which is to be bent down by an assistant beneath the arch of the pubes, and then the pern's and catheter to be cut through. 2479. Of the accidents which may occur after the operation, after- bleedin^ requires special attention. If it occur from a vessel which has not been tied during the operation, it must be taken up at once. If from the spongy bodies, it must be endeavoured to stanch it with cold water, styptic powders, and pressure, or when this is inefficient, and the length (a) Neue Biblioihekfur die Chirurgie und (6) Archives generales de Medecine, vol. Ophthalmologic, vol. i. p. 737. xxiv. p. 133. 1830. ' 546 REMOVAL OF THE PENIS BY TYING. of the stump permits, pressure is to be made on the tube already intro- duced with a roller, or strips of sticking plaster; but if these means be fruitless, the actual cautery must be employed. Violent inflammation and spasmodic retention of urine must be treated according to the ordi- nary rules. The tube in the urethra must not be removed till the scarring is com- plete, otherwise the opening of that canal is narrowed; and even then it is often necessary, as I have sometimes seen, to prevent the contraction by leaving a bougie in; on the other hand, there are cases in which without any bougie, no narrowing of the urethra ensues. After the most successful operation, even in aged persons, whose pro- creative powers have ceased, there, is often no means of preventing low- ness of spirits and melancholy. 2480. In removing the penis by tying, a silver male catheter must be passed through the urethra into the bladder, a waxed silken thread applied beyond the diseased, and upon the .healthy part of the penis, and intro- duced into a loop-tier or some particular instrument for tying a ligature. This instrument must be screwed so tight that the part before the ligature shall be deprived of all feeling; the instrument is to be fastened with sticking plaster, and the cancerous part covered with lint and compresses. On the second or third day, usually the largest portion of the dead penis may be removed with scissors or bistoury, without bleeding or pain; and on the fourth or fifth day the ligature separates. The catheter may now be removed ; a small silver or gold tube introduced into the urethra, and the suppurating part dressed simply till it scar {a). 2481. Amputation of the penis with the ligature is preferred by most practitioners to that by the knife. The inconveniences, however, which usually arise from the former, as great and continued pain, by which fever, convulsions and the like'may be produced, and the noxious effect of the sloughing mass upon the whole system, by which Graefe's mode of operation is beset, must not be overlooked. The most important advantage of tying is security from bleeding, which may be very severe at or after the operation, although proper caution will prevent this, as my experience has proved. [I have never seen any trouble or difficulty from the bleeding at or after the re- moval of the penis with the knife, and should think the scarring would be more quick, and much less painful by this method than by the ligature, of which, how- ever, I have not had any experience.—j. f. s/] 2482. As in many cases, although the carcinomatous swelling increases the penis to double its size, it does not attack its whole substance, but is confined to the cavernous bodies, so that according to Lisfranc, the degenerate mass may be removed by a cut made from before backwards beyond the diseased part, from the back of the penis, by short strokes of the knife, carefully cleansing the wound with a sponge till the whole fibrous covering of the cavernous bodies has been laid bare. If this be found healthy, the diseased mass must be carefully removed, and only (a) Biener, above cited.—Speier, E., Dis- von Graefe angegrebencn und verbesserten sert. de Castratione. Berol, 1820.—Michae- UnterbindungstOcken; in same, vol. v. p. lis, Ueber die Exstirpation des Penis durch 356.—Michaelis, Neue Erfahrungen iiber Ligatur; in von Graefe und von Walther's Graefe's Amputationsweise des Penis; in Journal, vol. iv. p. 331.—Bloemer, Ueber die same, vol. siii. p. 210. CANCER OF THE TESTICLE. 547 when the degeneration has penetrated more deeply should the penis be amputated. This opinion is supported by some successful cases, {a). F.—OF CANCER OF THE TESTICLE. Pohl, Programma de Herniis et speciatim de Sarcocele. Lips., 1739. Heise, (Praes. Heister,) Dissert, de Sarcocele. Helmst., 1754. Warner, Joseph, An Account of the Testicles, their Coverings and Diseases* London, 1774. 8vo. Pott, Percival, A Treatise on the Hydrocele or Watery Rupture, and other Diseases of the Testicle, its Coats and Vessels; in his Chirurgical Works, voL ii. London, 1783. 8vo. Marschal, Von der Castration. Sajzb., 1791. Bell, Benjamin, A Treatise on the Hydrocele, on Sarcocele or Cancer, and other Diseases of the Testes. Edinburgh, 1794. 8vo. Loder, Ueber die Castration; in Neue Medic. Chirurg. Beobachtungen, p. 110. Ehrlich, Beobachtungen von der Entmannung; in Chirurg. auf Reisen gemach- ten Beobachtungen, vol. i. cap. xiii. Daun, (Praes. Metzger,) Dissert, de Exstirpatione Testiculi. Kcenigsb., 1800. von Siebold, C, Praktische Beobachtungen uber die Castration. Frankf. 1802. Mursinna, Ueber die Castration; in neue Medic.-Chirurg. Beobachtungen 33-37. Sauernheimer, Dissert, de Sarcocelotomi.l. Col. 1807. Zeller, Abhandlung iiber die ersten Erscheinungen venerischer Localkrank- heiten, sammt Anzeige zweier neuen Operationsmethoden, namlich die verwach^ senen Finger und die Castration betreffend. Wien, 1810. von Siebold, C, Chiron, vol. i. part i. ------------, Sammlung chirurgischer Beobachtungen, vol. i. Ramsden, Thomas, Practical Observations on the Sclerocele, and other morbid enlargements of the Testicle; on Hydrocele and on Aneurisrri. London, 1811. 8vo. Wadd, William, Cases of Diseased Bladder and Testicle. London, 1817. 4to. Speier, Dissert, de Castratione. Berol, 1820. Cooper, Sir Astley, Bart., Observations on the Structure and Diseases of the Testis. London, 1830. 4to. Curling, T. B., A Practical Treatise on the Diseases of the Testis and of the Spermatic Cord and Scrotum. London, 1843. 8vo. 2483. The various chronic swellings to which the testicle is subject, and by which its parenchyma is converted into a foreign substance, are usually comprehended under the general designation Sarcocele {Sarcoele, Hernia carnosa, Lat.; Fleischbruch, Germ.; Sarcocele, Fr.) Under this term, are ranged together induration, scrofulous and syphilitic swelling of the testicle, scirrhous, sarcomatous degeneration, varicose swelling, and medullary fungus. Some writers confine Sarcocele to cancerous degeneration of the testicle; others name as Sarcocele a variety of ele- phantiasis, in which the skin of the scrotum becomes a fleshy substance, attached as it were to a neck, and with which generally the testicle is unconnected: it is most proper, however, to restrict the term Sarcocele, simply to the sarcomatous degeneration of the testicle. 2484. Scirrhus of the Testicles is generally preceded by inflammation or other external injury, or it occurs of itself without any apparent cause. The testicle swells, becomes hard; may continue a long while in this condition without causing any inconvenience; at last, after some acci- (a) Margot, Sur le diagnostic des divers lesquels on a preserve les Malades h l'Am- degres de profondeur des Cancers de la putation du Penis; in Revue Medicale,- Verge ; ct Observations sur deux Cas, dans 1826, vol. iv. p. 337. 548 SCIRRHUS AND SARCOMATOUS DEGENERATION dental irritation, or of its own accord, the swelling becomes greater, harder, irregular, and knobby, and lancinating pain runs along the course of the spermatic cord. The scirrhosity spreads over the cord, which thickens and becomes firm and knotty; the neighbouring glands swell; the skin of the scrotum adheres to the swelling, at last bursts, and an ulcer with hard out-turned edges, and a discharge of stinking ichor, or with fungous growths, is produced, and the pain becomes very severe, in the region of the loins and spermatic cord. Whilst this is going on in the testicle, the general health becomes very much affected, and the previously-mentioned symptoms set in. The interior of the hardened testicle consists of a hard tallow-like substance, of a grayish or brownish colour, oftentimes containing distinct cells filled with a sanious fluid. 2485. In Sarcomatous degeneration of the Testicle, its substance is changed in the same way as already described of Sarcoma in general, (par. 2281.) There is an excessive collection of coagulable lymph in the parenchyma of the testicle; the spermatic arteries and the branches they give to the coverings of the testicle are sometimes pretty numerous, and considerably enlarged. In sarcoma the testicle often retains its shape for a long while, is oval and flattened on both sides, its larger end is directed upwards and forwards, its smaller one downwards and back- wards. Its weight, in proportion to the size of the swelling, is always considerable. This disease generally causes no other inconvenience than that of dragging on the spermatic cord, if unsupported by a bag- truss. It is free from pain, the skin covering it has its natural condition, which is only first changed on very great enlargement of the swelling. The spermatic cord may indeed swell, but does not become knotty and knobby. If such sarcomatous swelling be left alone, or if it be irritated by treatment, it may run into cancerous degeneration. 2486. During the progress of scirrhus as well as of sarcoma of the testicle, a collection of wrater is not unfrequently formed in the scrotum, (Hydrosarcocele,) which is to be considered as a consequence of the degeneration of the organ. There is then felt a firm, regular swelling, and frequently distinct fluctuation. Sometimes the surface of the testicle unites with the vaginal tunic into one indistinguishable mass. 2487. The distinction of scirrhous and sarcomatous degeneration of the testicle from other swellings which occur in its parenchyma or its coverings, is in most cases exceedingly difficult, and requires careful examination of the swelling and of the way in which it arose. Swellings of this kind are, first, thickening of the cellular tissue of the scrotum; second, hydrocele ; third, hydatid or cystic tumour of the testicle; fourth, hardening of the tunica albuginea of the testicle ; fifth, fungus of the tunica1 albuginea or of the testicle ; sixth, induration of the testicle con* sequent on acute inflammation ; seventh, scrofulous and syphilitic swell- ing of the testicle ; eighth, medullary fungus. 2488. The thickening of the cellular tissue of the scrotum, which is infiltrated by a quantity of fatty, watery, or bloody fluid, forms a swelling with a broad base, and at the same time attached to a stem, of which the size is sometimes so considerable that the penis is complete- ly covered ; the dpening of the prepuce has the appearance of a navel OF THE TESTICLE; TREATMENT. 549 at the end of the swelling, and the patient is prevented walking. Its weight is sometimes as much as one hundred pounds. Externally the tumour presents various degrees of roughness, separated by the hol- lows which correspond to the crypte mucose or the roots of the hairs. Upon a large portion of the tumour when it has long existed are formed yellowish crusts or scales, which as they drop off leave a corresponding number of ulcers bare, and secreting an ichorous fluid. The swelling is painless, bears even violent pressure in various directions, is at some parts hard, at others soft, and is only troublesome to the patient by its weight. The testicle and spermatic cord are generally natural, only the spermatic vessels are lengthened. This disease is most common in hot countries, although it has also been noticed in France, England, and Ger- many. According to Larrey, who frequently saw it in Egypt, persons who sit at their work are peculiarly subject to it. Syphilis and other vicious states of the juices may be reckoned among its internal causes; the patient is frequently at the same time subject to elephantiasis, of which this disease seems only a modification. When the disease has not attained a very great height, its dispersion may be attempted by antimonial, mercurial, and diaphoretic remedies, by the alterative use of mineral acids in small quantities with mucila- ginous drinks. Externally by lotions of dilute sulphuric acid, solution of bichloride of mercury, of sulphate of iron, and of hydrochlorate of ammonia. If notwithstanding this treatment the tumour become larger, the ope- ration is the only remedy. For this purpose two cuts are made in front of the aperture of the prepuce which separate below»from each other, and run down on both sides, below the testicles. In these directions all between the cavernous bodies of the penis and the testicles, in wrhich care must be taken to avoid the testicles, spermatic cords, and cavernous bodies, and the whole mass below the line of the cut removed. The remainder of the sarcomatous mass must be shelled out. The bleeding vessels must be tied at once, and the edges of the wound brought together with sutures, sticking plaster, and a proper bandage {a). [This disease does not generally exceed such size as might render it liable to be mistaken for disease of the testicle itself; but with careful examination it is scarcely possible to mistake the one for the other. In some instances, however, the scrotum seems to participate rather than give origin to similar growths of cellular tissue, with adhesive deposit in its cells, which has been already mentioned, (p. 451,) and which has, perhaps, been not very cor- rectly spoken of as elephantiasis of the scrotum. These sometimes acquire very enor- mous size, and have occasionally been removed. Some such have been already noticed, but as their removal is attended with considerable danger, it would seem, from the sudden loss of venous blood, it will not be improper to advert to the sub- ject again. In Liston's case (b), already cited, of the tumour which weighed nearly fifty pounds, and was removed from a man of twenty-two years of age, the disease "had commenced when he was only ten years of age, and had gone on increasing gradually from that time. It measured forty-two inches in circumference, and forty (a) Ephemeridcs Nat. Curiosorum, 1692— und von Walther's Journal fur Chirurgie Morgagm, Epistolae Anatomicae. xliii Art. und Augenheilkunde, vol. ii. p. 647.—von 42.—Larrey, Memoires de la Chirurgie Froriep's Kupfortafeln, pi. cxxvi. Militairc, vol. ii. p. 110.—Richerand, Noso- (b) Edinburgh Medical and Surgical Jour- graphic Chirurgicale, vol. iv. p. 432. Fifth nal, vol. xi\. p. 566. Ib23. This account Edition.—Titley ; in Med.-Chir. Trans., is the most circumstantial, and is that here vol. vi. p. 71.—Delpech ; in von Graefe quoted. Vol. iii.—47 550 REMOVAL OF SCROTAL TUMOUR BY KEY; from the verge of the anus to the pubes, betwixt which parts it was attached. The greater bulk of the tumour lay behind, and extended lower than the patient's knees. * * * The incisions were made from behind. I had intended to preserve as much of the genitals as I might find it possible to do, on examiningtheir attachments and connexions with the diseased mass. But immediately on the bistoury being carried round the base of the tumour, the haemorrhage was so profuse that any at- tempt of the kind had to be abandoned, for the more essential and immediate object of saving the patient's life. * * * The tumour was therefore detached as rapidly as possible,—in not very many seconds,—and the mouths of the large and numer- ous vessels running into it covered as they were divided, by our fingers. The flow of blood was compared by those present to the discharge of water from a shower-bath, so instantaneous and abundant was it. Before half the vessels could be tied, the patient had sunk off the table without pulse, and with relaxed muscles, voluntary and involuntary." From this condition he was recovered, and then, in his Practical Surgery Liston states, the remaining vessels were from twelve to sixteen, but whether they were arteries or veins is not mentioned. In three weeks he was able to walk about, and soon after the complete cicatrization of the wound took place. The tumour is in the Museum of the Royal College of Surgeons of England. The following is Key's case (a), which from its enormous size excited great interest: Hoo Loo, aged thirty-two years, ten years previous to his admission (March 17, 1831) into Guy's Hospital, "first perceived the extremity of the prepuce to swell and become hard, and it continued to increase for about four years. At the end of this period the scrotum began gradually to enlarge up to the present time, when it had acquired the enormous magnitude of four feet in circumference, its increase having been for the last two years remarkably rapid. * * * The appearances of the tumour at the time of operation (April 9) were as follows:—Its body was of a flattened spheroidal form, four feet in circumference, and attached by an equila- teral triangular neck of half that size, which, opposite the pubes, measured exactly eight inches across, and extended about two inches and a half beyond each external abdominal ring. The other sides corresponded to the lateral boundaries of the perinaeum, and met at an acute angle immediately before the anus. Its length was such, that when the man was erect, its lowest point was about opposite to the tubercles of the tibiae. On its neck and lateral portions, the integuments were healthy in appearance, whilst on its anterior part they were considerably thickened, indurated, and had a tuberculated honey-comb appearance, with a few small ulcera- tions, from which a slight serous transudation took place. Near the centre of the body of the tumour, an irregular projection, supposed to be elongation of the prepuce, concealed the orifice from which the urine escaped. The integument covering this projection, seemed more diseased than that of any other part of the tumour, being closely studded with numerous small elevations of the cutis, and from this projection, an elevated ridge extended backwards through the medium line of the tumour, and evidently was the enlarged raphe of the scrotum. The plan of the operation was this :—To make three flaps ; one from the upper part of the neck of the tumour, to envelope the penis, and a semilunar one on each side to form a covering for the testicles and perinaeum." In making the first lateral " incision, several large veins were divided, which bled freely, but were immediately secured by ligatures. This flap was then dissected back, during which several large vessels were tied. At the lower part of the flap, one particularly large vein was secured. A flap of the same kind was made on the opposite side, during which, but comparatively few vessels were divided. The next step of the operation con- sisted in laying bare the cords; and in cutting down upon the right one, a small artery, the first that was seen, Was tied. At this time, the patient's powers appeared so depressed, that it was determined " no farther attempt should be made to save the penis and testes." Mr. Key, therefore, " passed a temporary ligature round each spermatic cord, and then divided them; A band was then passed round the penis in the same manner, which was then cut through about an inch and a half from its root. The tumour was now dissected from the perinaeum, which occupied (a) Removal of an immense Tumour, occupying the region of the Pubes and Perinaum; in London Medical Gazette, vol. viii. p. 93. 1831. BY O'FERRALL. 551 but a very short time; in this separation, two small arteries were divided, and instantly secured. The ligatures were then removed from the cords and penis, and each spermatic artery tied separately. During the greater part of the operation, and especially towards its latter end, the man's powers were greatly depressed, and two fits of syncope occurred, yet after it was finished, his pulse, though weak, could be felt at the wrist. However, in a few minutes another fit of syncope came on, from this he never rallied." Every means to restore him, including transfusion, were in vain. The operation lasted an hour and three-quarters; this was principally occasioned by the necessity of tying so many vessels, the whole of them veins, with the exception of three very small arteries, besides the two spermatios; and by being delayed during the two fits of syncope. Although upwards of thirty ligatures were applied, not more than twenty ounces of blood were lost, and of this scarcely one ounce arterial." * * * The weight of the tumour, when removed, was fifty-six pounds, eight ounces. Mr. Key was decidedly of opinion, and expressed himself to that effect, that the patient's death was occasioned by the loss of blood, which, though by no means excessive, from the precautionary measures adopted, yet made an impression on the feeble system of an Asiatic, which his powers were unable 1o overcome. * * * The tumour was found to consist of the cells of the cellular membrane enlarged, and containing a yellowish dense serum. Some parts of the tumour contained indurated masses, resembling cartilage. The tumour, when entire, undulated, and was thought by some to contain a large quantity of fluid in one cyst; but the fluid was contained, as is usual in elephantiasis, in cells of various dimensions, but none exceeding a marble in size. Warned by the fatal result of this case, and also from the violence of the bleeding in Liston's patient, 0'Ferrall(«), to guard against such untoward circumstances, in operating on "an enormous tumour of the scrotum of a man forty-four years of age, which descended nearly to his knees, disabled him by its great weight, and had nearly exhausted his strength by profuse bleeding from large veins on its surface," adopted the plan " of placing the patient on his baek, and having the tumour poised for a sufficient length of time to empty its vessels before the incisions were com- menced," and the result justified his expectations. The disease had commenced ten years before, in " a hard swelling on the cord, the size of a marble, about an inch above the left testicle," which "continued progressively to enlarge. * * * The last haemorrhage from the veins of this tumour amounted, he was convinced, to two quarts of blood. The exhaustion was very great, and rendered him for some time unable to pursue his avocations." When admitted into St. Vineent's Hospital, "the figure of the tumour was irregular; it arose by a pedicle from the pubes and perinaeum, and expanded in its descent into a huge mass, the widest portion of which was about four inches above its lowest part. The integuments which covered the pedicle were evidently borrowed by traction from the abdomen and groin, and pre- sented four distinct and prominent folds; the skin covering the tumour was smooth, it was marked by numerous large venous trunks, which traversed its surface, and lay in furrows easily traceable by the finger. A small ulcer in the integuments over one of these veins marked the point from which the haemorrhages had taken place. The left lateral aspect of the tumour, near its neck, exhibited several trunks of veins, larger than swan's quills, running parallel to each other, and, when the patient was in the erect position, projecting in strong relief. When poised upon the hands it gave the impression of considerable specific weight; its consistence was unequal; its hardest portion was an irregular mass of the size of an orange, of cartU laginous density, and situated about an inch below the left external abdominal ring. The greater portion of the tumour was solid, though not gristly to the touch. At two or three points of the remainder there was a degree of elasticity closely resem- bling fluctuation. * * * Of the penis, the glans was the only portion visible, it pro- jected from the integuments at a point about three inches below the pubes. The remainder of this organ was buried in the morbid growth. * * * From the pubes to the fundus of the tumour measured twenty-eight inches; the circumference about its middle was twenty-two inches and a half. The weight of this enormous mass was the principal source of inconvenience." The operation was performed on the 29th November, 1844. After making a puncture into the elastic part of the tumour (a) Malignant Tumour of the Scrotum; Science, vol. i. p. 521. 1846. New Se- in Dublin Quarterly Journal of Medical ries. 552 REMOVAL OF SCROTAL TUMOUR with a trocar, through the canula of which nothing but a little blood came out, and the patient being placed in the position for lithotomy, "with a large broad-backed bistoury, O'Febrall made in the perinaeum two straight incisions meeting at an angle, salient towards the anus. Keeping close to the tumour, the incisions were carried rapidly round its under and lateral surfaces, exposing on the right side the covering of the testicle, and on the left a bunch of cylindrical convolutions as large as the finger. * * * Their uniform blue colour, solid feel, and entire absence of gaseous contents, at once convinced us that it was an enormous varix of the cord of the left side. The tumour being now detaehed as far as possible laterally and underneath, was allowed to descend to a nearly horizontal position, in order to com- plete the operation in front. Two straight incisions carried downwards from the groins, were made to meet at an angle, so as to include a portion of integument capable of covering the urethra, and fitting into the incisions previously made. The tumour was now rapidly detached, and the cord being held, was cut across. A few strokes of the bistoury completed the separation of this enormous mass from the body of the patient. The vessels of the cord and a few small subcutaneous branches were now secured, and the patient was put to bed. The loss of blood was very inconsiderable, not exceeding perhaps four ounces." The operation was completed in eight minutes. After a few hours the flaps of integument were brought together with sutures. About nine days after the operation the patient was attacked with erysipe- las, which spread down the thighs, upwards over the body to the shoulders, then over the scalp and face, and after about seventeen days subsided completely. Shortlv after he had a fit of acute rheumatism, from which, however, as well as the general consequences of the operation, he rapidly recovered. On examination of the tumour, "a loose capsule of cellular tissue enveloped the morbid growth. A section carried through its middle showed that the whole was perfectly solid, and without the slightest appearance of a cyst. The cut surfaces reminded us strongly of the section of the larger varieties of fibrous tumour of the uterus,- whitish, with the slightest possible tinge of yellow. The substance appeared to consist of a number of lobules, separated by lines of condensed cellular tissue, and marked here and there by minute granules of ealeareous deposit. The greater number of bloody points presented by the seetion, however, distinguished its appearance from that of the fibrous tumour of the uterus. Some of the lobules almost resembled in density a section of the inter- vertebral substance. Others more elastic appeared to have undergone a change ap- proaching the character of encephaloid disease. This impression was confirmed by Dr. Houston, who found that it presented under the microscope the mixture of fibres and cells, characteristic of malignant structure. It was in these situations that the deceptive feeling of a cyst had previously existed. The left testicle was, after a careful search, found to occupy the position mentioned by the patient. It was atrophied, but otherwise unchanged, and lay enclosed in its moist and polished tunica vaginalis. The cord above it was lost in the tumour." In the very remarkable case related by Bennet (a), the disease had commenced "nine or ten years before, in the form of a swelling on each side of the groin, which gradually increased in size, descended, and, he says, united and formed one mass, entirely covering the perns." The tumour has been gradually increasing from that time, and has now reached to the insteps. The weight of the tumour, so far as could be ascertained, was about ninety-six pounds avoirdupoise, and tbe size, by careful measurement, was found to be as follows :—The length from the crest of the pubes to the base (bottom) of the tumour, two feet five inches; circumference of the upper part, just below the pubes, twenty-one inches; of the centre, four feet; of the largest part, just below the urethra, four feet eight inches. The tumour was at some parts smooth, at others had a wrinkled appearance, excepting at the lower part of its right side, which was tubereulated and livid; the general colour, however, was a dirty yellow. It was very callous to the touch, except at the upper part about the pubes, and a few inches below. The tumour was composed, as appeared on cutting into it, of an indurated substance, about the consistence of cartilage, and of a similar white colour. No operation was performed. In all these cases it will have been noticed, that the scrotum was only secondarily, not primarily affected.] (a) Case of enormous Tumour of the Scro. (Otaheite,) Southern Pacific Ocean; in Lon- t«ra ia a. Native, of the Island of Tahiti, don Medical Gazette; vol. viii. p.. 101. 1831. CYSTIC SWELLING OF THE TESTICLE. 553 2489. A simple hydrocele cannot well be confounded with sarcocele. Only at first, when the collection of water is not great, it is sometimes accompanied with severe pain on account of the distention of the vaginal tunic, which, in connexion with the great hardness of the swelling-, may lead to a mistake. But when that tunic is considerably thickened, and even cartilaginous, the feel is easily confused, and the practitioner may mistake the swelling for hydrosarcocele. In this latter complaint, how- ever, the hind part of the swelling is generally harder and knobby ; the spermatic cord is also usually knotty, and there is lancinating pain. In doubtful cases, puncture always resolves the difficulty. 2490. Cystic swelling of the testicle begins with a thickening of .the epididymis ; it is, however, generally only first noticed when the disease has spread over the testicle, and has made some progress. In addition to the swelling, the testicle retains its natural form, round in front, flattened on the sides, and not so bean-shaped as in hydrocele. Between the testicle and the epididymis, usually,, though not always, the natural line of distinction still remains. The sweLling is not tender if not subjected to violent pressure, but when smartly pressed, the patient feels as if the testicle were squeezed. The- tumour yields to pressure, though it does not show true fluctuation : if it be compressed at one part with the finger, it is not raised at another part, but merely appears to yield all over. Pain and uneasiness in the loins are produced by the weight and size of the testicle, although the disease still remains local. On examining a testicle of this kind after removal, the vaginal tunic is found thickened, in part adherent, and the tunica albuginea firmer ; the testicle appears to consist partly of firm tissue and partly of cysts, the size of which varies from that of the head of a la*ge pin to that of a musket-ball. The smaller cysts, of which the walls are very vascular, contain a serous, clear, or yellowish fluid, and the large s-, of which the walls are thick, have a mucous substance. Astley Cooper believes the cysts to be obstructed efferent tubes, into which a diseased secretion is poured out. Nothing precise is known of the occasional causes, the patient often ascribes the disease to cold, or to a blow. This tumour may be most easily confounded with hydrocele; the cystic tumour, however, is more compressible than fluctuating, heavier, the form of the testicle is retained, but rather more bean-shaped, is not transparent when a light is held behind it, and when violently pressed is painful as when the testicle is squeezed. In hydrocele, the testicle can be felt behind, although indistinctly. The removal of the testicle is the only remedy, and the recurrence of the disease not to be dreaded if the cystic disease be not complicated with medullary fungus, as may be seen after the removal of this organ, and always renders the prognosis unfavourable. True hydatids may also exist in the testicle {a). 2491. The tunica albuginea of "the' testicle is sometimes thickened, irre- gular, cartilaginous, and sometimes bony, the testicle, however, still retaining its natural condition. The swelling is in these cases painless, makes only irregular slow progress, and in general theie is a collection of water in the vaginal tunic. The disease has* no relation to cancer of (a) Astley Cooper, above cited, p. 63. 47* 554 MEDULLARY FUNGUS OF THE TESTICLE. the testicle, and does not require extirpation. Scirrhus may, however, be developed in the tunica albuginea which has adhered to the vaginal tunic, in which case, the scirrhosity in general attacks the epididymis, but the testicle, although surrounded with some serous fluid, is either little or not at all altered. Several observations appear to prove that after extir- pation of the testicle, its recurrence is to be but little dreaded (a). 2492. Fungus of the testicle or of the tunica albuginea, is a peculiar disease, easily mistaken for sarcoma. In general, after external violence, or after a clap, a swelling of the testicle begins, which is often very con- siderable and hard. A small abscess forms, with severe pain, bursts, and out of the aperture a fungus gradually grows. If, in this complaint, after the inflammatory affection of the testicle has diminished, the testicle itself be not very greatly enlarged or hardened, it is best to remove the fungus and the diseased part of the testicle, without taking away the latter completely. This is best done with the knife, and in some cases the ligature or caustic may be employed. When the whole substance of the testicle is attacked with this fungus, it must be completely removed. The mere swelling and induration of the testicle, often ceases gradually after the extirpation of the fungus, and with proper treatment (b). 2493. Induration of the testicle, as a consequence of previous acute inflammation, presents a hard, usually irregular, though not rarely, knobby swelling, whieh is more or less painful on examination, but gives the patient no lancinating pain. Repeated application of leeches, softening poultices, rubbing in mer- curial or iodine ointment, and continued rest, usually effects its disper- sion. Scrofulous swellings of the testicle are less hard and painful than scir- rhus: the testicle is thereby converted into a yellowish-white coagulated substance, like that found in scrofulous glandular swellings; but the spermatic cord is, for the most part, in its natural state. The swelling, however, frequently runs into ulceration, forms a painful readily bleeding fungus; the spermatic cord swells, and not unfrequently there is scro- fulous degeneration. In most cases these swellings are resolved by proper general treatment, and by the local application of resolvents. Syphilitic swellings of the testicle and spermatic cord, in consequence of an inveterate pox, arise slowly, without any occasional cause, and commonly are developed in the epididymis. A regular mercurial treatment most commonly effects their dispersion. 2494. Medullary fungus of the testicle is distinguished from sarcocele, by the more speedy growth of the swelling to a large size, by the absence of all hardness and irregularity, by the very indistinct pain, by the delusive feel of fluctuation, by the quick affection of the spermatic cord, and the spreading of the disease into the belly (par. 2295.) 2495. Most of the above-mentioned diseased states are distinguished from cancer of the testicle; they may, however, even if left alone or treated improperly, run into cancerous degeneration. It is, therefore, {a) Dictionnaire des Sciences Medicates, vol. i. p. 13-15. (b) Lawrence; in Edinburgh Med. and Surg. Journal, vol. k.p. 257.—Dictionnaire des Sciences Medicale, vol i. p. 16. EXTIRPATION OF THE TESTICLE. 555 necessary when suitable treatment has been employed without effect for some time, to extirpate the testicle, because thereby alone is the passage into cancer prevented. For scirrhus of the testicle there is no other remedy than extirpation. In sarcomatous degeneration, by repeated local bleeding, by dispersing applications, and by the internal use of such remedies as promote absorption, the unnatural vegetative process may be kept down, or by tying the spermatic artery, the tumour may be diminished, or its growth prevented. 2496. Extirpation of the testicle {Castratio, Lat.; Entmannung, Germ.; Emasculation, when both testicles are removed) is for the patient a very painful, and, in cancerous degeneration, as to its consequences, a very doubtful operation, as recurrence of the disease is very common. The expectation of a favourable result is greatest when the disease has been the consequence of external violence, is not connected with, any general affection, and all the degeneration has been completely removed. It must be held to be contraindicated when there is any existing general disease, on which the disease of the testicle depends; when the neigh- bouring glands are swollen, and there is also disease of the spermatic cord, when the hardness extends so far up, that excision in a healthy part is not possible. If in such case there be also dragging pain extend- ing up into the loins ; if the swelling of the spermatic cord be hard, knotty, and the seat of lancinating pain. From this scirrhous degeneration of the spermatic cord, which in rare cases may precede the swelling of the testicle, a simple sympathetic swelling of the cord may be distinguished by its regularity, by not being knobby, and by diminishing towards the abdominal ring, and by the pain lessening when the testicle is supported by a bag-truss. A swelling of the spermatic cord may al*o depend on serous infiltration into its vaginal sheath. When with sarcocele swellings in the belly are connected (1), which on closer examination can often be distinctly felt, as well as with decided appearance of cancerous dyscrasy, the operation can only hasten death (a). (1) The swellings which often form enormous masses m the belly, occur, indeed, generally in medullary fungus of the testicle; I have, however, seen them also in true cancer of that organ. 2497. For the purpose of rendering the removal of the testicle in sar- cocele superfluous, Walther {b) has proposed tying the spermatic artery, which has been performed successfully by Maunoir (c). This operation can, however, only apply to those diseases of the testicle, in which a very copious deposit of plastic lymph into the cellular tissue of the testicle has caused unnatural development of vessels and sarcomatous degeneration, but no passage into cancerous degeneration. In relation to this practice stands cutting through the spermatic eord with inter- ferring with the testicle, which soon wastes (d). 2498. Tying the spermatic artery in sarcomatous swelling of the tes- (a) Rust, Zwei Beobachtungen iiber eine (b) Neue Heilart des Kropfes, u. s. w., p. eigene Erhartung des Hodens, als Folge 40. Sulzbach, 1817. einer Varicositat der Lymphgefiissc, beson- (c) N uvelle Methode de traiter le Sarco- ders der Cysterna chyli und des Ductals cele sans avoir recours & PExtrrpation du Thoracicus; in Horn's Arehiv. IS 15.— Testicule. Geneve, 1830. 8vo. Girel, Ueber den Fungus, die Struma testi- {d) Weinhold; in Hufeiand's- Journal, culi; in Neue Chiron, vol. i. p. 273. vol. viii. part iv. 1842. 556 EXTIRPATION OF THE TESTICLE ; tide is unaccompanied with any difficulty. A cut half an inch long must be made at the abdominal ring in the direction of the cord, which being laid bare, the pulsation of the very much enlarged artery may be felt. The vessel is to be isolated as high up as possible, by slightly cutting the cellular tissue surrounding the spermatic cord, and passing a single thread with Deschamps' needle around it without including the vas deferens, nerves, or veins. The wound is to be brought together with sticking plaster, (par. 1538.) 2499. The removal of the testicle is performed in the following way. The scrotum and neighbourhood of the abdominal ring having been cleared of hair, the patient should be placed horizontally on a table. The operator standing on his right side, nips up the skin in an oblique fold over the spermatic cord, gives one end of it to an assistant, and himself holds the other with the thumb and finger of the left hand. This fold is now cut into in the course of the cord, and extended upon a director up towards the abdominal ring and down to the bottom of the scrotum. The cellular tissue surrounding the spermatic cord is now to be separated by some cuts lengthways on the sides, and the cord lifted up, the cellular tissue beneath it being thus made tense, is cut through with the knife held flat, and as the knife is brought back, the operator passes the forefinger of bis left hand into this opening, thereby stretches the remaining cellular tissue, and with his finger separates the cord up to the abdominal ring. The testicle being lifted up to lessen the stress upon the spermatic cord, an assistant grasps the cord above where it is to be cut through, and the operator holds it below, passes the knife beneath and divides it at a stroke. The arteries are now to be taken up with forceps or with a hook, and having been cleared are to be tied. The testicle is to be shelled out of the scrotum, by which wounding of the urethra and the septum scroti are avoided. All the bleeding vessels are to be tied immediately* When the skin of the scrotum is diseased, or firmly adherent to the tumour, it must be included either between two semilunar cuts, or after the eord has been divided, and the arteries tied, the testicle, and the skin covering it, must be removed with the knife, by which all injury to the Septum is avoided. Any other practice for stanching the bleeding, than tying the vessels, is improper. If the cord escape from the assistant, and retract into the inguinal canal, it must be attempted to seize it with the forceps and pull it out, or even the external wall of the canal must be cut into (1). Aumont (a) cuts through the skin at the hinder part of the scrotum, which is to be raised and turned to the opposite side, from the bottom of the swelling to the ab- dominal ring. The testicle, which is laid bare by this wound, is then to be dis- sected up, and the cord bared to the abdominal ring; the testicle is then held by an assistant, and the cord, with forceps, by the operator, who cuts through it, and ties the arteries. The advantage of this is, that a smaller cut is made upon the least feeling part of the scrotum, and that the cord is more easily laid bare to the abdominal ring; hence its division and the tying of the vessel's is more easy, there is less danger of after-bleeding, the eseape of the secretion of the wound is more free, and its union better. [(1) The escape of the cord immediately on its division is a very tiresome, and, to a young operator, very perplexing accident; to prevent its occurrence, Astley Cooper used to advise passing a thread through the cord, above-the place at which the division was to be made, which gave full' power over the upper end of the cord after its division, and the thread was removed after the spermatic vessels were tied. (a) Bulletin de k Societe d'Emulation de Paris. 1822. April. TREATMENT OF UNDESCENDED TESTICLE. 557 I prefer passing a strong tenaculum through the cord, which answers the purpose quite as well, and is more quickly done.—j. f. s.] 2500. If the spermatic cord be degenerated so far towards the abdominal ring that it cannot be held fast by the assistant, a ligature should be passed round, after isolating it, which should-be bound to a piece of wood, and there held till the artery have been cleared and tied. To this case alone should the complete tying of the whole cord, by many con- sidered as the proper mode of proceeding, be confined. The tie should then be made as tight as possible, which alone prevents the severe symp- toms caused by lying nerves. If the degeneration extend so high up on the spermatic cord that it cannot be cut through in a healthy part, the inguinal canal must be opened, and the healthy part of the cord there cut through {a). [Much stress was formerly laid upon not Aying the whole cord before dividing it, on account of the severity of the pain; I cannot say, however, that I ever noticed it so violent as stated, or, indeed, worth noticing, in the many times I saw it tied by some of the older surgeons, in the early part of my studentship. But tying the cord is objectionable, for a much better reason, which is the length of time the ligature requires to ulcerate through. The younger Cline managed ihe matter differently; he used to pass a strong thread around the cord, brought both ends through a piece of pewter catheter, tied them upon a stick at the top end, and then twisted stick and string, till like a suck-tourniquet, which it really was, it had compressed the vessels so completely as to prevent bleeding, when the cord was cut through. The thread was left on till the fourth or fifth day, then untwisted, and one end having been cut through, the thread was removed, if there were no bleeding. This practice I have often seen him pursue with great success.—j. f. s.] 2501. When the removal of the testicle is completed, the wound is to be cleansed, the extremity of the cord laid lengthways in it, and the ligatures fastened with strips of plaster. The wound is brought together with three or four stitches, and with strips of plaster, upon which are placed some soft lint, and compresses, and the whole fastened with a T bandage. The patient must be kept for the first twelve days pretty much in the horizontal posture. The after-treatment depends on the degree of the inflammatory and nervous symptoms which set in, and is conducted according to the usual rules. 2502. A not unfrequent inconvenience after the operation is bleeding, which, if not quickly attended to, may produce very considerable infil- tration and distention of the loose cellular tissue of the scrotum. If, after removing the dressing, some bleeding vessels be discovered, they must be tied. If the bleeding be from the whole surface, as if from a sponge, which, even at the time of the operation, may happen, attempts should be made to prevent it by cold water, and other styptic remedies, together with moderate pressure. If the bleeding will not so stop, the varicose part of the edge of the wound must be removed ; in one case I found it necessary to stitch along the whole edge of the wound with a needle and thread. 2503. If the testicle have not descended into the scrotum, but remain lying in the inguinal canal, or at the abdominal ring, so much earlier do (a) For peculiar instruments to tie the pi. xii. fig. 1-4.—Rudtorffer, above cited.— spermatic cord, see Ravaton, Pratique Mo- Joachim, in Thault, above cited.—Graefe, derne de la Chirurgie, vol. ii. pi. ix. fig. 1,2, in Biener and Speier, above cited. 558 DISEASED UNDESCENDED TESTICLE. the symptoms of disease appear, partly from its confined position, and partially by the various results of violent exertion, and the like. There may occur inflammation, induration, scirrhous degeneration, and collec- tion of water in the cavity of the vaginal tunic. In all cases where the testicle lies at the groin, it is advisable to bring it down into the scrotum, by opening the scrotum and the abdominal ring. The spermatic cord offers no obstacle thereto, as it has its natural length, and lies coiled up behind the testicle. To keep the testicle in its place, a loop may be passed through the vaginal tunic and the bottom of the scrotum, and moderate pressure made at the abdominal ring (a). If any such testicle be hardened, it may be exposed in the same way, and the spermatic cord, which is easily distinguished, divided. [The operation here recommended should not be performed as it is useless and cruel. The testicle, though seated in the groin, performs its functions equally well, and if there be any fear of its situation rendering it liable to injury, it may be pro- tected with a cup truss. It is of great importance that persons who are subject of this unusual position of the testicle, should be acquainted with the fact of it being matter of not the slightest consequence to their condition, as very serious mental alienation has occurred from their notion of being unlike other people, and incapable of performing an important function. In some instances, indeed, the horror of their presumed condition has led to self destruction. Neither must it be omitted to mention that, although the testicle has been seated for many years in the groin, yet that occasionally, without any ap- parent cause, it will descend and take its natural place in the scrotum.—!, f. s. There is not any reason why the testicle remaining in the groin should not be attacked with disease, as it is after its descent into the scrotum ,• but such cases, as far as I am aware, are exceedingly uncommon ; the following three examples are therefore very interesting; the first two are histories attached to casts in the Museum of St. Bartholomew's Hospital, for which I have to thank my friend Paget; and the last is now (November) in the Middlesex Hospital, under the care of my friend Arnott, who has kindly furnished me with his notes. Case 1. The man was a labourer, aged forty-four years. His mother said, that at the time of his birth a small tumour was observed in his groin, which has remained there ever since. Seven years before his death it began to increase considerably in size, and six weeks previous to Mr. Sargant seeing him, in November 1830, it had attained such bulk as to incapacitate him from following his usual employment. At that time it seemed attached to the anterior superior spine of the ilium,and to the upper part of the pubes, and hung down over the thigh; and was considerably in- flamed. Treatment was adopted calculated to remove this condition: and soon after he came to St. Bartholomew's Hospital; but in January 1831, he returned to Mr. Sargant's care. The tumour had then greatly increased in size, and was slightly inflamed, accompanied with considerable fever and general disorder. Mild anti- phlogistic remedies were adopted, and after the application of a blister, were main- tained for a week; the tumour pointed at its most depending part, and having been punctured, a pint and a half of green, offensively-smelling matter was discharged. He was allowed nutritious diet, with wine, &c, and was soon able to leave his bed and walk in the open air, about eight ounces of matter, however, being discharged daily. In the following April, his strength having regularly increased, he was able to walk four or five miles in the day, and the tumour continuing to discharge, was much decreased in size. On the 1 Ith of the same month, haemorrhage, to the amount of about a quart, took place, it was supposed from a branch of the epigastric artery. After this he seemed, for a time, to have recovered his previous improved condition; but in the beginning of June was attacked with fever, occasional shiverings, great and most distressing pain in the loins, and the tumour again rapidly and consider- (a) Brevting, Dissert, de Testic. retropr. chelegenden Testikels. Munchen, 1820.— post bine extirpat. cum adn. circa monorch. Chei.ius; in Heidelberger kliniach. Annalen, et testicondos. Landgli., 1814.—Rosenmer- vol. ii. part iii. eel, Ueber die Radicalkur des in der Wei- chimney-sweeper's CANCER. 559 ably enlarged. The discharge at this time was lessened; but on the 20th of the same month, a fresh opening was spontaneously made near the former one, and from this a copious discharge ensued, accompanied about every three days with a dis- charge of about eight ounces of blood. The bowels now became obstinately costive, and he had great irritability of stomach, with constant retching and vomiting. He continued in this state, but gradually becoming worse, and on the 27th of July died. On examination, the stomach, liver, and spleen were found healthy. The mesenteric glands were considerably enlarged and indurated, and on being cut into, discharged the brain-like substance observable in medullary sarcoma. The testicle could not be found ; nor could the spermatic cord be traced beyond the tumour,, though it was carefully sought for. What remained of the tumour was a mass of soft encephaloid substance. Case 2. Was under the care of Lawrence of Brighton, and the cast was made on account of its similarity to the former. In this also the testicle had not descended into the scrotum, and it was presumed that it was an encephaloid tumour of that organ which had produced the enlargement. Case 3. Richard Long, aged 43 years, was admitted into Middlesex Hospital. Nov. 3, 1846. On account of a tumour in the right groin; it is large, prominent, and of an oval shape, with its long diameter nearly in the direction of Poupart's liga- ment, which, however, it covers somewhat obliquely; the greater part of the upper and outer end of the mass of the tumour being above the ligament, the greater part of the lower and inner end being below its level. Over the surface it measured nine inches in the long direction, and six and a half in the short. It extended from within two and a half inches of the anterior and superior spinous process of the ilium, to a little beyond the pubes, where it was in contact with the root of the penis. Its surface was uniform and smooth ; it felt firm and resisting, and gave the idea of solidity, but at one part communicating an indistinct sensation of some fluid being present; it is nowhere diaphanous. No impulse is communicated on coughing, although from the motion on its surface during this action, it is evidently covered by at least the superficial fascia of the abdomen. It can be grasped, and is to a certain extent moveable, but it cannot be fairly raised from its attachments behind. The scrotum and testicle on this side are wanting. The patient, a farm-labourer, of hale appear- ance, and father of seven children, states, that he never had a testicle in its proper place on the right side, but that up to four years ago, there was a small swelling, the size of a nut, in the groin, and he points to a situation above Poupart's ligament, corresponding to the internal abdominal ring, or upper part of the inguinal canal. That it was unattended by pain. Four years back, as he was one day engaged at his work, making trusses of hay, it came lower down; and he tried to get it up again, but without success. It was then, he states, the size of a walnut, and has continued gradually to enlarge ever since, but without pain or inconvenience, except from its increasing bulk. " Viewing the case," says Arnott, "as one of disease of the undescended testicle, but unable to determine its precise nature, whether hydrocle or haematocele with a thickened tunica vaginalis, cystic sarcoma or malignant disease, I this day (Nov. 5) told the patient that it would be necessary to puncture the tumour, and then proceed according to its nature, so as even to remove it if necessary. His mind not having been prepared for this, and no application having hitherto been used, he wishes some trial of these to be made in the first instance; and as he has but just entered the house, he will be indulged." Nov. 13.—The operation Was performed to-day, and the case found to be one of medullary sarcoma of the testicle, which had never got out of the external ring, the diseased mass being covered with the tendon of the external oblique, which I had to slit up over the whole length of the swelling.] G.—OF CANCER OF THE SCROTUM. Pott, Percival, Chirurgical Works, vol. ii. p. 225. Edit. 1783. Simmons, W., Observations on Lithotomy; to which are added, Observations on Chimney-sweeper's Cancer. Manchester, 1808. 8vo. 560 TREATMENT OF CHIMNEY-SWEEPER'S CANCER. Earle, Henry, On Chimney-sweeper's Cancer; in Med.-Chir. Trans., vol. xii. p. 296. Travers, Benjamin, On same; in same, p. 344. Earle, Henry; in London Medical Surgical Journal, vol.i. p. 6. 1832. Cooper, Sir Astley, Bart., Observations on the Structure and Diseases of the Testis, p. 226. 2504. Under the name of Chimney-sweeper's Cancer, Pott has de- scribed a peculiar cancerous degeneration of the scrotum, to which the chimney-sweepers in England are subject (1). A warty excrescence sprouts upon the lower part of the scrotum, which may remain unchanged for months and years ; it forms a superficial but painful ill-conditioned ulcer, with hard and outturned edges. Almost invariably young persons are attacked with this complaint, so that not unfrequently it is taken for a venereal affection, but antispyhilitic treatment of all kind, renders it more painful and makes it worse. In a short time the ulcer spreads over the skin of the scrotum, penetrates deeply, and attacks the testicles, which swell and become hard. Hence it spreads along the spermatic cord to the viscera of the belly; the glands in the groin swell, and the patient sinks under the severity of the pain from extensive ulceration (2). [(1) " Other people," says Pott, "have cancers of the same parts, and so have others besides leadworkers the Poictou colic, and the consequent paralysis, but it is nevertheless a disease to which they are peculiarly liable ; and so are chimney- sweepers to the cancer of the scrotum and testicles." (p. 227.) According to Dr. Paris (a) " it deserves notice that the smelters are occasionally affected with a cancerous disease in the scrotum, similar to that which infests chim- ney-sweepers, and it is singular that Stahl in describing the putrescent tendency in the bodies of those who die from this poison, mentions in particular the gan- grenous appearance of these parts." (p. 97.) Although the disease almost invariably is produced in the scrotum, yet in rare cases it is seen on other parts. Earle mentions '"a remarkable instance of its oc- currence at the wrist of a gardener, who was every spring employed to distribute soot for the destruction of slugs, which is related by his father in the last edition of Pott's Works" (p. 297.) Astley Cooper saw chimney-sweeper's cancer twice, and Keate once upon the cheek. (2) Earle states that when from infection by this disease, the tpsticle "becomes greatly indurated, ulceration, and sometimes sloughing, then take place, leaving a deep excavated ulcer, that penetrates into the body of the testis, which does not ap- pear disposed to the formation of fungous growth similar to what occurs when the scrotum is the seat of the disease. The same observation applies when the com- plaint has extended itself to the inguinal glands; its progress in glandular structures appears to be more rapidly destructive, without the slightest effort at reparation. The disease in every instance that I have seen, except one, extended itself to the parts immediately contiguous. The inguinal glands are often enlarged, but they will generally subside on the removal of the diseased scrotum, clearly proving that the disease is not commonly communicated in the course of the absorbents. This is a very important feature in the complaint, and one which most materially influences the prognosis and treatment. I know but one exception to this rule, where a bubo formed, which suppurated, and the sore assumed the same character as the primary affection in the scrotum." (p. 298.) This statement of the subsidence of a swelled inguinal gland, is very remarkable, and if generally supported, would form a very important and hopeful feature in the disease; but I am afraid experience does not verify it.—j. k. s. Travers (b) says:—"The disease resembles lupus of the cheek and eyelids in destroying the skin and cellular texture, leaving the testicles and ligamentous covering of the crura penis, as that does the sclerotic, bare and wasted, but other- (a) Pharmacologia, vol. ii. London, 1825. 8vo. Sixth Eition. (b) Med.-Chir. Trans., vol. xvii. 1832 CANCER OF THE WOMB. 561 wise uninjured. This sore has no tendency to slough or penetrate deeply by ulcera- tion. The lymphatic glands are rarely, and seldom, specifically affected." (p. 345.)] 2505. The cause of the disease must be considered to be the ingrim- ing of soot into the wrinkles of the scrotum (1). It rarely occurs before thirteen years of age (2), and appears at first to be simply a local disease, although there may be a general disposition thereto {a.) The only remedy to prevent the progress of the disease is cutting out the ulcerated part of the scrotum, or its destruction with arsenical oint- ment. If the operation be put off till the testicle be affected, extirpation has in general an uncertain result; and in many cases although the wound have completely healed, the disease may re-appear some months after (3). When it has once spread so far that the removal of the testi- cle is no longer possible, palliative treatment according to the general rules, alone remains. [(1) It may be this disease depends on some chemical peculiarity of coal soot, as foreign writers take no notice of its occurrence in countries where wood is used for fuel.—j. f. s. (2) Pott says he never saw chimney-sweeper's cancer under the age of puberty. And Earle states:—"It very rarely attacks persons under the age of thirty, who form a very small proportion of the number engaged in the business. The greater proportion of cases which I have seen, have occurred between thirty and forty; I have seen three instances between twenty and thirty, and only one at the age of puberty. A solitary instance is recorded by my father, where it occurred in an in- fant under eight, but I have never met with any similar case." (p. 299.) (3) I have lately had under my care a man, for whom my colleague, Green, removed a chimney-sweeper's cancer nineteen years since; the disease having recurred. The return of the disease seems evidently to depend on exposure to the cause which originally produced it, as so far as I am aware, if persons change their occupation, it does not recur, if removed before the glands have become tainted.— j. f. s.] H.—OF CANCER OF THE WOMB. Roederer, S. G., De Scirrho Uteri. Gottingae, 1754. Haller, Comment, de Uteri Scirrho. Gottingae, 1756. Joeroens, Ueber den Scirrhus und das Carcinoma der inneren weiblichen Ge- burtstheile; in Hufeland's Journal, vol. ix. part. i. Wenzel, C, Ueber die Krankheiten des Uterus. Mannheim, 1817; with plates. Beyerle, F. J,, Ueber den Krebs der Gebarmutter. Mannheim, 1817. Patrix, Traite du Cancer de la Matrice et sur les Maladies de Voies urinaires. Paris, 1824. von Siebold, E., Ueber den Gebarmutterkrebs, dessen Entstehung und Ver- hutung. Berlin, 1824. von Siebold, E. C. J., Dissert, de Scirrho et Carcinomate Uteri, adjectis tribus totious Uteri exstirpationis observationibus. Berol., 1826. Schmidt, W. J., Erfahrungs-ResultUe iiber die Exploration bei dem Scirrhus, Krebs und anderen krankhaften Zustanden des Uterus; in Harless's Jahrbiicher der deutschen Medicin und Chirurgie, vol. i. p. 74. Schmitt's obstetr. Schriften, p. 100. Wien, 1820. Bn ndell, James, M.D., Extirpation of the Uterus; in London Medical Gazette, vol. ii. p. 291, 733, 7H1. 1828. Montgomery, W. F., M. D., Observations dn the Incipient Stage of Cancerous Affections of the Womb; in Dublin Journal of Medical Science, vol. xx. p. 433. 1842. {a) Earle, Med.-Chir. Trans., p. 299. Vol. in.—48 562 DIAGNOSIS Churchill, Fleetwood, M.D., Outline of the Principal Diseases of Women. Dublin, 1835. 12mo. Ashwell, Samuel, M.D., A Practical Treatise on the Diseases peculiar to Wo- men. London, 1844. 8vo. Simpson, James Y., M.D., Case of Amputation of the Neck of the Womb fol- lowed by Pregnancy; with Remarks on the Pathology and Radical Treatment of the Cauliflower Excrescence from the Os Uteri; in Edinburgh Medical and Sur- gical Journal, vol. Iv. p. 104. 1841. 2506. Cancer of the womb almost invariably commences in its neck, and in general upon the hind lip of its mouth. At first the symptoms are doubtful, and not distinguishable from any other irritable state of the "womb. Most commonly menstruation is irregular, sometimes a sanious sanguinolent discharge, or a copious white discharge, with an uneasy sensation of tightness and dragging in the loins, frequent disposition to void the urine, tenesmus and darting stabs through the neck of the womb. On examination, the vaginal poition is found partially or completely hardened, and in some parts loosened up. The mouth of the womb is also notched, irregular, and half open. On pressure with the finger, a sanious fluid mixed with blood flows out. [" In the great majority of instances," observes Montgomery, " the first discover- able morbid change, which is the forerunner of cancerous affections of the uterus^ takes place in and around the muciparous glandulae or vesicles, sometimes called the ova Nabothi, which exist in such numbers in the cervix and margin of the os uteri; these become indurated by the deposition of scirrhous matter around them, and by the thickening of their coats, in consequence of which they feel at first al- most like grains of shot or gravel under the mucous membrane ; afterwards, when they have acquired greater volume by further increase of the morbid action, they give to the part the unequal, bumpy or knobbed condition, like the ends of one's fingers drawn close together. When this second stage (usually described by writers as the first) is established, all means hitherto devised have failed in producing any permanent benefit." (p. 439.)] 2507. The disease may remain in this state many months, and even years, The symptoms become more severe, spread over the pubes and thighs, the discharge becomes very ichorous, stinking, and mixed with pieces of slough and clots of blood ; frequently there are very violent bleedings. The general health is much affected ; all the symptoms of cancerous consumption, with the characteiistic leaden countenance, make their appearance, and death ensues, either quickly, or after a se- vere bleeding, or as is usual, under the horrible tortures of hectic con- sumption (1). On examina'ion of this advanced state of the disease, the vaginal por- tion is found ulcerated, more or less destroyed, beset with warty growths and hard knots, which ascend into the cavity of the neck of the womb. Sometimes the womb itself, sometimes the upper part of the vagina is hard and degenerated ; the ulceration may even extend to the rectum and bladder, in consequence of which the sufferings become more severe. [(1) " The popular opinion, that cancer of the womb is invariably accompanied by acute suffering is," observes Ashwell, "certainly incorrect. But it is true that in some instances, scarcely any infliction can equal, and certainly hone can exceed, its agonizing, burning and lancinating pain. * * * By most the pain is de- scribed to be lancinating, as though sharp knives were constantly being plunged into the neck of the womb ; and so constant is this characteristic, that some authors found on it the diagnosis between corroding ulcer and cancer. There are, however, Hot a few cases in which the hot burning character constitutes its great aggravation. OF CANCER OF THE WOMB. 563 In the milder forms, where the progress is very slow, the pain is wearing and con- stant, but endurable." (p. 414.) "These pains," remark Bayle and Cayol (a), "are sometimes so acute, that persons have been known to die of convulsions, or delirium, occasioned by cerebral fever." (p. 415.) Montgomery (b) mentions an instance in which " the last five or six weeks of the patient's life were grieviously embittered by the most uncontrollable and inces- sant vomiting, accompanied with slight pain and tenderness on pressure over the stomach, but not in other parts of the abdomen." And Ashwell mentions a case, "where the malignant ulceration, commencing in the indurated deposit of the urethra, extended into the vagina,- the aggravated pain was greatly alleviated by belladonna and conium, used topically; the appetite and health were so far improved, and the ravages of the disease so much checked for a considerable time, as to inspire the hope that a respite of at least many months might have been obtained. But just as these expectations were at their height, agonising pain suddenly and inexplicably recurred, and the patient sank in less than a week." (p. 334.) 2508. Cancer of the womb, like cancer in general, exhibits many varieties in its progress ; in persons with dense fibre, it is rather the pro- gressive ulceration of scirrhous parts, but in pasty persons it is mostly accompanied with fungous growths and very copious bleedings. The diagnosis is in general easy, and the more so as the practitioner is usually only first consulted when the disease has made some progress. Those diseased conditions, which at first have some resemblance to cancer of the womb, but are easily distinguishable, are chronic inflam- mation and benignant hardening, steatomatous (fibrous degeneration, eversion of the womb, polyp, and medullary fungus. [The " Cauliflower Excrescence from the Os Uteri," as it is called by Dr. Clarke (c), is a form of disease by some regarded as truly cancerous, and by others as a morbid tissue, not necessarily of a malignant or carcinomatous nature. Upon this point Simpson observes:—" A number of circumstances appear to me to show, that, in reference to, at least, the first stage of cauliflower excrescence, the opinion of these latter authors is probably correct. The occurrence of the disease in some cases as early as the twentieth year of life ; its occasional shrinking, and almost total disappearance upon the application of a ligature, or after death ; the frequent slowness of its general progress during life; the apparent absence of dis- eased deposits in the neighbouring tissues and parts upon the dead body; and above all, the alleged restriction, and even complete removal of the tumour in one or two instances, by the use of astringent applications and other simple means, form so many circumstances strongly pointing to the opinion, that in the earlier part of its progress, the tumour cannot be regarded as of a carcinomatous character. Has it any analogy in its pathological nature and origin—as it certainly has in its physical characters—with the soft warts and condylomata that sometimes form on the mucous membrane of the vulva and entrance of the vagina? These warts and condylomata have the same tendency to degeneration after their imperfect removal, and present to us a striking exception to the general pathological law of the local reproduction of a morbid growth being a sign of its malignancy. But whatever view we may take of the primary nature of the cauliflower excrescence of the cervix uteri, we have sufficient evidence for believing either that this disease has been often confounded with carcinomatous or medullary fungus from the cervix uteri, from the want of ade- quate diagnostic marks to distinguish them; or that, though non-malignant in its commencement, the cauliflower excrescence may, like some other local benign growths, become the seat of carcinomatous deposit and malignant action, during its progress." (p. 109.) May the degree of mobility of the cervix uteri serve in any case as a source ofdiagnosis ? " The tendency of cancer," as observed by Muller (d), (a) Quoted by Ashwell. provement of Medical and Chirurgical (ft) Dublin Hospital Reports, vol. v. p. Knowledge, vol. iii. p. 21. 1809. 434. (d) Neue Zeitschrift fur Geburtskunde, (c) Transactions of a Society for the Im- vol. iv. 564 MODE OF USING THE SPECULUM VAGINA, " is to interfere with the natural structure of surrounding parts, while those forma- tions which are of a benignant nature, leave the neighbouring healthy tissues un- altered." (p. 176.) In carcinomata of the cervix uteri, we thus generally find, even at a pretty early stage of the disease, that the organ has become more fixed and im- moveable than natural, in consequence of the morbid deposit affecting both the structure of the neck of the organ and the contiguous surrounding tissues. Does the reverse of this hold good with regard to cauliflower excrescence of the cervix uteri? (p. 110.)] 2509. Cancer of the womb may be developed at every period after puberty; it however, most commonly appears between the fortieth and fiftieth years in women whose sexual functions have never been in proper order, and who have had much trouble and care. Mechanical injuries operating on the womb, rough treatment in delivery, constant irritation of the womb in its dropping down or protrusion; irritating astringent injections for flooding or for the whites, very frequent connexion, espe- cially with disproportion of organs, as well also as frequent venereal excitement without connexion, and luxurious living at the climacteric period, must be considered as the most common and active causes of cancer of the womb. Syphilis, gout, and scrofula, are also frequently in causal relation with cancer of the womb; and hereditary disposition is not unfrequently noticed. ["Cancer is not often a disease of the young; although some years ago," says Ashwell, "I attended a case with Dr. Pierce, where the patient had not reached her twentieth year. Boivin and Duges, in four hundred and nine examples, found twelve under twenty years of age; eighty-three, between twdnty and thirty; one hundred and two, between thirty and forty; one hundred and six, between forty and fifty-five; and ninety-five, between forty-five and fifty. Mr. Carmichael saw a case at twenty-one years of age; and Wigaud adduces one of scirrhous uterus at fourteen years." (p. 375.)] 2510. The cure of cancer of the womb has been attempted by internal and external remedies, and by the destruction or removal of the diseased part. 2511. As to the employment of internal and external means, only in such cases may a favourable result be expected from them when the dis- ease is not actually cancerous, but is simply benignant swelling and hard- ening, or that state of ulceration which, under neglect or improper treat- ment, may run into actual cancer. Hence, the successful issues which have been observed by means of proper antiphlogistic treatment, repeated application of leeches to the sacrum and to the upper part of the thighs, and in full-blooded persons even blood-letting, and at the same time the use of calomel, hemlock, digitalis, belladonna, aqua lauro-cerasi and the like, soothing baths and injections into the vagina, purgatives, and when the cause has been syphilitic, properly managed mercurial treatment. In true scirrhus or cancer, the remedies directed (par. 2415) for cancer in general may indeed lessen the sufferings, but never effect a cure. This, as in cancer in general, so in cam;er of the womb, is only possible by the removal, or by the destruction of the scirrhous or cancerous mass. 2512. It is self-evident that the circumstances already mentioned {par. 2410) as regarding operations on cancer in general, which either render them difficult, impossible, or contraindicate them, are still more weighty in reference to their application to cancer of the womb, as decision upon the extent of the degeneracy, and the participation of the patient's health, is, subjeqt, to still greafer diffipulty than under other, qircumstance,s. IN CANCER OF THE WOMB; EXTIRPATION. 565 2513. Examination with the greatest attention can alone ascertain the condition of the womb, as well also as an inspection of the parts by means of the speculum vagine which must be passed into the vagina as high as possible, so that the neck of the womb may be received into its upper opening, which can alone be distinctly distinguished when the speculum is illuminated with a candle. The specula uteri et vaginae are rather conical cylinders of tin polished on their interior (Recamier, Dupuytren, Dubois and others); or two-armed (Lisfranc, Jobert, Duges, Ricord); or three-armed (Busch, Ehrmann, Weiss); or many- armed (Grillon Beaumont, Colombat.) The two-armed are usually most con- venient. The following circumstances are to be attended to in the introduction of the speculum uteri. The patient is to be laid opposite the light upon the edge of a bed or table, with her buttocks a little raised, and her feet supported by assistants, or resting on a stool. The practitioner standing between the thighs, separates with the fingers of his left hand the labia, and holding in his right hand the speculum, warmed and smeared upon its external surface with grease, passes the part next the commis- sura labiorum posterior some lines deep into the vagina, presses it upon the commis- sure, and at the same time raises the handle, so that the part resting against the pubes descends from the urethra into the vagina, and is carried to its very end. The two arms of the speculum are now separated by gentle pressure on the handle, and then by the admission of the daylight, or by holding a taper, the state of the vaginal part of the womb can be observed (a). [Simpson (b) has made the following valuable observations, in reference to the mode of using the speculum vaginae. "It is almost unnecessary, we believe, to insist at the present day, upon, the importance o*f the early and accurate local ex- amination of the uterus, in all cases of suspicious vaginal discharges. In some instances, examination by the finger may be sufficient, but in every doubtful case the speculum should likewise be resorted to, if there is any affection of the vagina or cervix. We have found it often confirming, and not unfrequently, also changing and rectifying the opinion which the mere tactile examination had led us to adopt. In this country great difficulties have been placed against the more general introduc- tion of the speculum into practice, in consequence of the disagreeable and revolting exposure of the person of the patient, which is usually considered necessary in its employment. We have latterly in our own practice endeavoured to avoid this very natural objection, by teaching ourselves to introduce and use the instrument when the patient was placed on her left side, in the position usually assumed in making a tactile examination, and with the nates near the edge of the bed. We strongly recommend our professional brethren to follow this plan, as by it, and with attention to the management of the bed clothes, we have found that the instrument can be perfectly employed with little, or indeed without any exposure of the body of the patient. The speculum is introduced easily without the assistance of sight, and the mouth of it only requires to be afterwards uncovered, in order to enable us to ex- amine the cervix uteri and top of the vagina. We have made trial of many different forms of specula, and find, fo* almost all purposes that of Ricord by far the most manageable. " In exposing the cervix uteri for the purpose of drawing blood from, it by scarifica!- tions, in cases of chronic congestion and metritis, we have occasionally employed a tubular speculum with advantage, but even in this case thedouble-bladed instrument is equally useful, and in some instances preferable. In a case of ulcer of the os uteri, which we are at present attending with. Dr. John Gairdn.er, and where the passages are much relaxed, and the uterus very low in the vagina, we have, on Dr. Gairdner's suggestion, employed with much advantage a short tubular speculum of only an inch and a half in length, and with a deficiency or opening along the course of one side of it, of sufficient size to enable us to pass our finger,, for the purpose of placing the diseased part in the proper centre of the instrument. We have thus been enabled to (a) Lisfranc, Du Toucher; fn his Cfinique Chirurgicale; in Gazette Medicale, vol. i. p. 591. 1833. (b) Above cited. 48* 566 TREATMENT OF CANCER OF THE WOMB touch easily the ulcerated surface with different, applications; while with the usual instruments it was found a very difficult task, to fix in this instance the very mobile cervix uteri." (pp. 105, 106.)] 2514. Cases of successful extirpation of prolapsed and everted womb (par. 1289) first inclined B. Osiander to the performance of this opera- tion for cancer of the womb, or rather of its lower part thus degenerated. Osiander has described two modes of performing this operation. First.—The fungus is to be first removed, then the womb fixed in the bottom of the vagina by means of a thread drawn through its neck or by means, of forceps, and afterwards the degenerated neck cut off by an arching cut with a curved, narrow, round-ended bistoury. The bleed- ing must be stanched by plugging, or, by styptic powder. °Second.—lf the greater part of the neck of the womb be destroyed by Gancer, if it have spread far, and its cavity be filled with knobby, carcino- nxatoxxs fungus, and the mouth of the womb cannot be seized and drawn down with needles, the patient must be placed in the horizontal posture, the womb thrust down by pressure on its fundus, which must be fixed in the cavity of the sacrum with the forefinger of the left hand, the middle and "ring-fingers introduced into the cavity of the womb, and whilst they perform the cut with a panvof curved-bladed scissors, or an extirpating instrument, all the fungous irregular scirrhous parts are removed in small pieces. The cavity is then filled with sponge moistened in wine and styptic powder, and after the-bleeding is stanched a sponge dipped in lead wash and vinegar is to be passed up, When suppuration comes on if must be encouraged- by a mixture of extract of green walnut-shells, honey and red precipitate applied upon a sponge immediately to the surface of the wound. As the suppuration increases the mixture is to be used in smaller, quantity, and. without the precipitate. At the same time, internal strengthening medicine must be given (a). 2515. Dupuytren's method is more simple and efficient. The patient having been placed in the same position as for lithotomy, he introduces the speculum vagine and gives it to an assistant to hold. He then grasps the neck, of the womb with a pair of forceps, draws it slowly towards him, and cuts, off'the whole of the degenerated part of the.neck of the womb, either with a.dbuble-edged bistoury curved towards its side, or with a pair of scissors curved-in like manner, which are used above, below, and on both sides in such way that their concavity is always directed towards the neck of the womb. The bleeding in this operafion is generally in- considerable, though it may be great and even severe, in which case, if ^proceed from any one single spot of the wound, that may be touched with a,small actual cautery iron ; but if the bleeding be from the whole surface, it must be stanched by tightly plugging the vagina. If inflam- matory symptoms occur, corresponding antiphlogistic treatment must be employed. After suppuration is set up, four, or six injections of warm water must be made, and afterwards a weak solution of chloride of lime thrown up. If there be a, luxuriant growth of granulations they must be touched with nitrate of silver. In two or three weeks at most the wound has scarred (b). (a\ Reichsanzeiger. 1803-. No. 300 ; p. (fc) Sabatier, Medecine Operatoire, vol.nL 3926.—Gottinger zelehrter Anzeiger. 1808; p. 97. 1824.' New Edition. p. 1300. BY CAUSTIC POTASH \ ITS EXTIRPATION. 567 Canella (a) has given a peculiar speculum vaginae, together with forceps and a curved knife, with which, when the neck of the womb is drawn, into the cavity of the speculum, the degenerated part may be cut off. J. Hatin (b) has also proposed a speculum, vaginae, which may be expanded at pleasure, and by it an instrument can be introduced into the cavity of the womb, for the purpose of fixing it, and then with a jointed uterotome the projecting part of the neck of the womb can be cut off. von Walther, in a case, the account of which is still to be expected, first sepa- rated the pubic arch, and then cut off the neck of the womb. When the neck of the womb, on account of its softening or destruction, will not permit the application of the foreeps, the vagina and peritoneum must, according to Recamier, be cut into before and behind, and the womb then seized with the forceps, drawn down, and the degenerated part cut off. Lisfranc (c) employs a speculum vaginae, consisting of two half cylinders of tin connected by a hinge, and which may be separated from each other. After its intro- duction, the enlarged neck of the womb can be seen, and the necessary instruments introduced. With Museux's hook-forceps, made longer and stronger than usual, he seizes the neck of the womb, and with an artificial lever, acting for from five to fifteen minutes, produces a prolapse, and cuts off the degenerated part with a bis- toury at several small strokes. Colombat (d) has, for the purpose of preventing the pain in drawing down the womb, invented a hysterotome, with which, after the introduction of the speculum vaginae, the neck of the womb can be seized and cut off. Bellini (e) has invented a spoon, with a cutting edge in front and a long curved handle ; and Cenulli (f) and Aronsohn (g) other, instruments for extirpating the neck of the womb. 2516. When the degenerated neck of the womb is so soft that it can- not in any way be fixed without tearing, or wThen the disease recurs after it has been removed^ its destruction by caustic is indicated; For this purpose Recamier uses nitrate of silver, and Dupuytren nitrate of mer- cury dissolved in nitric acid, and caustic potash, which is preferable. Mayor's (h) practice of tying the neck of the womb with the assistance of forceps- must also be mentioned*. 2517. The caustic potash is to be applied in the following manner: — The patient having been placed in the same posture as for excision, and the speculum vagine introduced, the cancerous surface is to be eleansed with a wad of lint, pressed against it with the forceps for a sufficient time. If the surface of, the ulcer be irregular and beset with fungous growths, they must be removed with-scissors curved towards-their sur- face, or with a proper extirpation-knife. A wad* of lint must then be placed below the surface of the ulcer, to suck up all the fluid part of the caustic which escapes during the process ; the whole surface of-the ulcer- is now carefully dried withjint, and a conical piece of caustic potash, at least an inch broad at its base, blunt at its tip, and fixed on a holder, must be applied for at least a minute, unless the patient should suffer very great pain, which is rare. After this the vagina must be injected (a) C('nni:deH' Estirpazione della Bocca c del Collo dell' Utero et Pcscrizione del Me- trotomo, etc. Milano, 1821. (6) Memoire sur un nouveau procede pour l'Amput;itionMiu Col de la Matrice dans les Affections Cancereuscs. Paris, 1827. (c) Costeh, Manuel de Medecine Opera- toire, p. 138. (d) Memoire sur 1'Amputation du Col de la Matrice dans les Affections Cancereuscs, Buivant un nouveau ptocede; in Revue Medic cale. 1828; vol. ii. p. 194>—Lisfra\c, Me- moires eur l'Amputation du Col de I'Uterus, par Avenel; in Revue Medicale. 1828; vol. iii. p. 5, p. l!)9. le) Omodei, Annali Universalis vol. xkii. p. 355. 1828; (/) Archivo delle Seienze Med.-Fisiche Toscm. 1837 ; pi. i. (g) Hamburger Zeitschnft, vol. i. part iv. {h) Archives Generales de M&Jecine, roL xvi. p. 91. 1828;. 568 TOTAL EXTIRPATION several times with water, the speculum and wad of lint removed, and the patient put into a lukewarm bath. In four or five days, when the irrita- tion has passed off, and the slough has separated, the operation is to be repeated in the same way, if the state of the parts seem to require it. Should symptoms of inflammation of the womb and of the peritoneum occur after the operation, strict antiphlogistic treatment will be requisite. This mode of practice, although it will not ever effect a cure, in most cases relieves the patient considerably (a). 2518. It is evident that this mode oftreatment is alone indicated, and a cure thereby effected, when the disease is in its beginning, when there is not any accompanying general exciting cause, nor any ensuing affection of the whole constitution; when the exhaustion is not very great, when there is not any aff'ection of the neighbouring parts, and when the seat of the disease is such that the whole degenerated part can be removed. The result of the operation is, however, here just as doubtful, and even still more so than in the extirpation of any other cancerous part; because, cancer of the womb is liable to escape the most careful examination of the extent of the disease. On the other hand, however, it must be re- membered, that in cancer which arises in the neck of the womb, the boundary between the healthy and degenerated part is in general sharply defined, whereby the result of the operation can be the earlier determined, as cancer of the neck of the womb, as it is commonly developed, is a consequence of continued local ailment (b). Experience, however, is opposed to those who have denied the successful result of such partial extirpation (c). But a review of these cases proves that, on the other hand, the value of the operation has been overrated, as it brings about temporary, but very rarely lasting benefit, whilst fatal results have fre- quently ensued; and in the successful cases the correctness of the diagnosis may perhaps be doubted. 2519. Extirpation of the whole womb, if there be no accompanying prolapse, has by some been considered impossible ; by others absolutely fatal; by some holding out no hope of a favourable issue; because in the case indicating it, the disease has so far advanced that no resistance can be expected from its extirpation (d) Struve (e) proposed to effect a prolapse of the womb by drawing it down with forceps, separating the vaginal portion with a semicircular cut, tying the vessels, and freeing the womb from its ligaments. Gutberlat (/) proposed extirpating the womb, having previously made a cut through the walls of the belly, in the linea alba. C. Wenzel (g) proposes the extirpation of the whole womb, having first pro- (fl) Bulletin de la Faf,ulte de Medecine. No. VI. Juin, 1819.—Patri.k, abov'' cited, p. 145.—Sabatiek, above cite. 5.76. —Ammon, l arallele der franzOsischen und deutschen Ch.uurgie, p. 257. (6) Canella, Giornale di Chirurgia Prat- tica. Aug., 1825, (c) Siebold; in his Lucina, vol. i. p. 403. —Wenzil, C, U ber dio Krankheit n. des Uterus. Mainz, 1816..—Zang, Operationen, vol. iii. p. 392.—Joerg, Aphonsmtn ueber die Krankheiten des Uterus, zur Wurdegung zweier von Hofrath Osiander; in Leipzig unternotnmenen Operationen, Leipzitr, 1820. (d) Paulv, Maladies de l'Ute,rus d'apr&s les Legons Cliniques de M. Lisfranc. Paris, 1836.—Pigne; in his French transla- tion of this liandbuch. (e) Hufelani>'s Journal, vol. xvi. part iu. p. 123. 18:3. (/) Siebold's Journal fur die Geburt- shi'ilfe, vol. i. par? ii. (g) Abuve cited. OF CANCEROUS WOMB. 569 duced an artificial prolapse, by means of a pair of strong, toothed polyp-forceps, and then tying it with a ligature round its base, which is gradually tightened. Langenbeck (a) undertook the extirpation of a protruded carcinomatous womb; he dissected off the protruded vagina from its connexion with the womb, without cutting it through ; separated the peritonaeum from the substance of the womb, till the upper edge of the base of the latter was freed from its peritonaeal covering, which he then cut off in such way that a small healthy portion of its substance still remained attached. After this shelling, the peritonaeum formed with the vagina an empty sac, which, when the bleeding was stanched, he filled with lint. The ovaries and round ligaments should be removed together with the womb. Laud Wolf (b) extirpated a scirrhous prolapsed womb with a fatal result. Recamier (c) successfully removed one by tying it. He also (d), in a case of cancer with polapse of the womb, removed it, after ascertaining that no bowel was contained in the sac of peritonaeum, by means of a needle carrying a double thread, and tied on each side. 2520. The assertion of the impossibility of extirpating the whole womb, has been disproved by a case in which Sauter (e) performed this operation successfully. He considers this operation, having never seen any cure by partial extirpation, as suitable and practicable, when there is in the vagina, around the neck of the womb, still sufficient space to allow the knife being carried around all the diseased part, and when no general symptoms exist which contraindicate the extirpation. [That a patient can recover after extirpation of the womb, even under most un- favourable circumstances, is proved by the case related1 by Rossi (/), in which, after the delivery of both child and placenta, the midwife, on passing her hand into the vagina, felt a swelling, which she mistook for another child. This she pulled with such force, that the tumour, which was the womb, was dragged from its attachments, and then cut it off the vagina with a knife, and removed it entire. Notwithstanding this horrible treatment the woman recovered.] 2521. Sauter lays down the following rules for this operation:— After emptying the bladder and the rectum, the patient is laid across a bed and properly fixed. An assistant passes his hand over the pubes, in such way, that with the flat of it he' can press down the womb into the pelvis, whilst with the back, the bowels are kept up and away from the pelvis. The operator introduces the fore and middle fingers of his left hand into the vagina, till they reach the hollow-it forms around the neck of the womb; then carries a curved bistoury, with a short blade and long handle, between the fingers, up to this part, cuts through the vagina upon the womb, about two or three lines deep, and carries this cut around the whole neck. A pair of scissors, curved towards their edge, with long handles, are now passed between the two fingers, and a snip made between the bladder and rectum upwards through the peritoneum, keeping close to the neck of the womb, whilst with the fingers like a hook, the tough cellular connexions are grasped, directed into the scissors, and with these carefully cut through. When the division is so far made that the two fingers can be passed through the opening into the cavity of the belly, the separation may be made in a like manner between the (a) Neue Bibliothek fur die Chirurgie (e) Die ganzliche Exstirpation der carci. und Ophthalmologic, vol. i. p. 551. nomatosen Gebarmutter, ohne sdbst ent- (b) Archives generales de Medecine, vol. standenen oder kunstlich bewirkten Vorfall X. p. 105. 1826. vorgenommem und glucklicli vollfuhrt; mit (c) Revue Medicate. 1825; vol. iv. p. naherer Anleitung, wie diese Operation 393. December. gemacht werden kann; mit Abbild. in (d) Recherches sur le Traitement du Can- Steindr. Constanz, 1822, cer, &c. (/) H Raceoglitore. 570 EXTIRPATION rectum and womb, with scissors curved towards their blades, and kept close upon the womb. If the fingers can be passed on the hinder sur- face of the womb through the peritoneum into the cavity of the belly, this hinder connexion may be completely divided through the whole depth of its deeper sinking, up to its connexions on the sides, after the finger like a hook has been passed over the peritoneum, and that has been drawn down, with a concave knife or a pair of scissors curved on their side. .The height to be separated should be about an inch. The further the hind connexion be separated from below upwrards on the sides, the easier and safer can the operation be completed, after separa- ting the connexions on the sides. 2522. Thus far, by the introduction of the two fingers of the left hand into the vagina can every thing be effected as to the management of the knife and scissors, but now the whole hand, or at least four fingers, must be passed between the urinary bladder and the womb up into the open- ing in the peritoneum, so that its inner surface may be turned back. Then with the fore and middle fingers, hooked, the highest connexion on one side being drawn down from above, and somewhat forwards, a concave knife is introduced, carried above the side connexions by means of the fingers, and then keeping close to the womb by continued sup- porting and carrying the knife with and between the fingers, the side cut downwards towards the vagina, is made, and afterwards in like manner on the other side, before the division of the former is completed. The remaining side connexions are now set free, for which the two fingers are alone needed, keeping close on the womb and endeavouring not to cut from the vagina, but continuing the division into the first-made cut in the vagina. 2523. If there be much bleeding, a wad of dry lint should be first passed into the vagina, then large pieces of German tinder placed round its wall within the pelvis, and the vagina plugged with either more Ger- man tinder or lint. If the bleeding require no attention, after a wad of iint has been passed into the vagina, dry lint, or mixed with gum-arabic, must be introduced, but the vagina is not to be plugged. The patient is then to be put to bed in the horizontal posture, and then the assistant removes his hand, which had prevented the descent of the bowels, from above the pubes. The after-treatment must be conducted according to the general rules, with special attention, that the horizontal posture, with rest, should be continued for at least fourteen days, and if purifying injections into the vagina be necessary, they should be made carefully, so that nothing pass into the cavity of the belly. The vagina must never be stopped below with lint. 2524. von Siebold (a) has twice performed extirpation of the whole womb. He introduced a catheter into the bladder, so as more surely to avoid it, and then with Savigny's fistula-knife, divided upon two fingers behind the transverse branch of the share-bone, the right side of the vault of the vagina, close to the vaginal portion of the womb, and afterwards the left side. For the purpose of passing the whole hand, (a) Beschreibnng einer vollkommenen Exstirpalion der Scirrhosen nichtprolabirten Ge- barumtter. Frankfurt, 1824. OF CANCEROUS WOMB. 571 the perineum must be cut through, so that the ala vespertilionum may be divided with the polyp-scissors to the very fundus of the womb. In the second case, after the division of the top of the vagina, a thread is passed by means of a flexible silver needle through the neck of the womb, for the purpose of preventing the recession of that organ. Langenbeck (a) has extirpated the womb once through the vagina, and once by a cut through the white line as proposed by Gutberlat. Palletta (b) ex- tirpated the womb wTith a sarcoma attached to its neck; in this case he drew the sarcoma inwards, cut into the upper part of the vagina, with a pair of long curved scissors, and completed the removal partly with them and partly with a sickle-shaped knife. Holscher (c) proceeded in a like manner. 2525. Blundell {d) made a cut into the hind part of the vagina, passed in two fingers to enlarge the opening, and then again used the bistoury to increase the cut on both sides to the root of the round liga- ments. He then introduced his whole hand into the vagina, and two fingers through the opening in the peritoneum; upon these, a hook, which he fixed in the hind surface of the womb, and therewith drew it down, at the same time using the finger of the hand he had introduced as a blunt hook to act upon the fundus of the womb. In this way he brought the whole of the diseased mass near to the external opening of the vagina. He now cut off the ligaments and the Fallopian tubes close to the womb, and the vagina from the bladder with care, so as to wound neither its neck nor the ureters. The operation occupied an hour. Five months after the patient was well, well nourished, and perfectly cured. Blundell also undertook the extirpation of the womb in other three cases but all were fatal. Banner (e) seized the neck of the womb writh a strong hook, drew it down, and fixed it with a loop carried through it. He then divided with a semilunar cut, the hinder uppermost part of the vagina, where it is attached to the womb, and separated the womb from the bladder. The body of the womb was then turned forwards, and the ligaments were divided. The patient lost about six ounces of blood, and died on the fourth day. 2526. Delpech (f) considers a partial removal of the neck of the • womb as never sufficient in any cancerous affection of the womb ; as every mode of examining the extent of the diseased change is fallacious. Nothing, but the complete removal of the womb can be of use. The dangers of this operation are, wounding the peritoneum, tearing the parts, bleeding, and especially tying the broad ligaments of the womb. All these dangers are greater in extirpating the swelling through the vagina, but less in that through the white line, where isolated tying of the vessels is possible. In one case, Delpech made a semilunar cut through the skin above the pubic symphysis, and another in its axis in the peritoneum. With one finger in the vagina and another in the wound, he passed a pharyngotome through the vagina, and thrust (a) The same, p. 31. (e) London Medical Gazette, vol. ii. p. (b) Journal von Graefe und von Wal- 582. 1828. TH*R, vol. v. part iii. (/) Mdmoire sur l'Ablation del'TJterus; (e) The same. in Memori 1 des Hdpitaux du Midi. Oct.^ (d) Above cited, p. 295. 1830; p. 695. 572 EXTIRPATION it through the upper wound, whilst a hollow cylinder kept up the vagina. He then passed an elastic sound, and a metallic loop, drew the broad ligaments into the tube, divided them and tied the vessels singly. A loop was next carried round the womb, which was then cut off'. The result was fatal, in consequence, as Delpech supposes, of the tying. For the removal of the womb, whilst still in its place, Delpech gives the following directions: first, separation of the bladder from the womb' through the vagina, after having passed a catheter into the bladder; the finger to be pressed up to the peritoneum, which must be penetrated with the finger-nail; second, a cut above the pubic symphysis, in which a semicircular flap is first formed through the skin, and the white line which is at its base being divided to the extent of five inches, the peri- toneum lifted up with the forceps, and cut into ; third, one finger being then passed from above downwards between the bladder and the womb, to the one or other side of the neck of the latter, raises the corresponding part of the bottom of the vagina, and with it the lateral ligament of the womb on that side into the wound. A cut is now made upon the finger or upon an elevator in its stead, from above downwards, and as each vessel is cut through it is tied. The other side is managed in the same way. The womb is then pulled forwards, and its connexion with the rectum divided, and sponge passed into the vagina. 2527. According to Dcjbled {a), after the neck of the womb has been seized and drawn down to the entrance of the vagina, the upper and fore part of the latter must be cut through, the opening enlarged with the v finger, and the peritoneum stripped off; and the same must be done on the hind part. A ligature is then passed over the free edges of the lateral ligament, and that part of the latter surrounded which encloses the vessels of the womb, after which the lateral ligaments are cut through. The womb is then easily thrust down, and its diseased part cut through by a transverse cut, without interfering with its fundus. The patient died twenty-two hours after this operation. 2528. Recamier (b) proposed a mode of proceeding, which like that of Sauter is specially distinguished by avoidance of bleeding, and in one case wTith success, the patient being cured on the forty-third day. Clysters were given on the evening and morning before the operation. The patient was placed as in the operation for the stone, and the neck of the womb having been seized with Museux's forceps, was drawn down as low as possible. The vagina was then cut through with a convex button-ended bistoury, introduced on the left forefinger, on the fore and Under part of the swelling. The cellular tissue between the bladder and womb was separated with the left forefinger up to the folds of the peri- toneum, and the convex bistoury passed along the finger, following the upper surface of the womb, opened the peritoneum, into the cavity of "Which the finger was introduced upon the body of the womb. With a straight button-ended hernial knife, introduced in the same way, this opening was enlarged right and left, till two fingers could be readily placed upon the body of the womb, so as to bear it more forcibly down. (a) Journal Hebdomadaire, vol. vii. p. 123. (b) Above cited, vol. i. p. 519. CANCEROTJS WOMB. 573 With the same knife the two upper thirds of the left broad ligament were cut into close to the left side of the womb, and immediately after the right broad ligament in the same way, the left fore-finger carrying in the bistoury. The left fore-finger was n6w passed behind the remainder of the right broad ligament, and the thumb placed on its outer and fore part, so that with these fingers it was grasped and a thread carried round it with a needle having a stem and an eye at its point. In this part of the ligament the uterine artery was found, taken up and tied moderately tight with a loop-tier. The same was afterwards done on the left side. The left fore-finger being now placed behind and the thumb before the liga- ture, the rest of the broad ligaments were cut through with a button-ended bistoury, carried close to the si-de of the womb, whilst the fingers pro- tected the ligature. The same was afterwards done on the left side. The womb being now thrust out of the vagina, the bistoury was tarried between the womb and the rectum, upon the fold of the peritoneum, and divided it, and the edge of the knife being directed obliquely from above downwards, and from before backwards, cut through at last the upper and hinder part of the vaginti. Both loop-tiers were now turned up- wards, and with their threads laid upon the pubes. If the omentum or bowel protrude, they must be 'Carefully replaced ; and the perfectly hori- zontal posture of the patient will prevent its recurrence. The urine must be drawn off' with a catheter, and the treatment must correspond to the symptoms which occur. If the suppuration be of bad kind, careful in- jections of lukewarm water should be used. In dividing the l&pper third of the broad ligament, the little artery of the ovary cannot, according to Recamier, well give rise to bleeding on account of the exten- sion of the ligament, and if it be not divided with a very sharp bistoury. This part may be compressed with the finger, torn, and even a thread carried round it with a much-curved needle. The ligaments of the womb should always be cut through gradually,so that the divided parts maybe kept close to the external pudic aperture. Roux has extirpated two cases of cancerous womb in this way. Both died on the second day. 2529. It is superfluous to speak particularly of the difficulty of this operation, and of the dangers which may follow it. Of all the cases men- tioned in the preceding paragraphs, the whole excepting Sauter's, Blun- dell's and Recamier's, had a quickly fatal result, and even in these three cases the consequences were not permanent. Sauter's patient had a vesico-vaginal fistula, and died four months after of exhaustion and consumption ; Blundell's died within the same year of cancer of the vagina, and Recamier's patient can scarcely stand or walk, so doubtful is the permanent result. But without it, according to our present know- ledge, those who suffer from cancer of the womb, are certainly doomed to a most painful death. Of the several modes of practice described, that of Recamier seems to be the best. Gendrin (a), after having collected all the known cases of extirpation of the womb, proposes the following mode of extirpating the womb, by which he endeavours spe- cially to ensure stanching the blood, and lessening the painful dragging in bringing down the womb, as he considers that nearly in all the cases which have died in the first two days, death has not been caused by the inflammation, but by the depression of the powers from the pain in dragging down the womb during the operation. (a) Observations et Remarques sur l'Extirpation de l'Uterus; in Journal General de Medecine, p. 91. 1829. Oct. Vol. iii.—49 574 EXCISION OF WOMB BY THE ABDOMINAL SECTION. The patient is placed as in the operation for the stone, and a wooden gorget intro- duced into the vagina for the purpose of pressing aside any excrescences at the neck of the womb, and fixed at the highest part of the vagina on the right edge of the neck of the womb. Upon this gorget a bistoury wrapped in linen to within six lines of its tip, the extremity of which is covered with wax, or a pharyngotome is pushed to the upper part of the vagina six lines deep from below upwards, and from behind forwards, so as to pass into the broad ligament of the womb. A blunt-ended hernial knife is now carried into this little opening and enlarges it from above downwards in the wall of the vagina to the length of eight or ten lines according to the extent of the disease. After removing the bistoury and gorget, the hand is passed into the vagina, and the fore-finger into the wound ; the uterine artery is found along this cut in the upper third of the vagina, six lines in front, at the bottom of the triangular space forming the boundary of the connexion between the vagina and bladder. The parts are to be separated either along the cut or further up, where it is distant at least-ten lines from the vagina, so as to get at the womb in the broad ligament. A ligature can then be passed round the womb either with a blunt, curved, aneurysmal needle, or what, is easier with a thickish leaden thread, to which a ligature is attached and held by its outer end. If it be not possible to get hold of the artery alone, it may be compressed with the wall of the vagina by a plate of lead. The same is to be done on the left side. A button-ended bistoury very concave on its cutting edge is now passed into the cut on the left side, with which the wall of the vagina is divided horizontally to the right; the instrument must be supported by the right fore-finger, introduced half its length into the vagina, and the handle managed with the left hand. The front wall of the vagina is now divided and both the side cuts connected, i If the operation be performed high up, the vagina and peritonaeum may be divided together, before and behind,- by two transverse cuts. If the peritonaeum be not at the same time divided, a pharyngotome is carried deeply into one of the two side cuts at the back of one broad ligament through the peritonaeum, which after having been previously stripped off as far as possible with the finger, is to be divided with the hernial knife, first behind and afterwards before; and in doing this the whole left hand must be employed for using the knife in the vagina. A double hook or a pair of hook forceps are now fixed in the body of the womb, which must be drawn gently down, without bringing it into the vulva. The whole hand having been passed into the vagina, is pushed into the cavity of the belly, the hernial knife carried behind the right ligament of the womb, which is made tense, the body of the womb being drawn to the left by the hook, and the broad ligament divided from behind forward, whilst the bowels are kept back with the fingers. The other side is to be managed in the same way drawing the womb to the right. The womb must now be twisted obliquely on its axis, and gradually withdrawn. [Excision of the Uterus by the'Abdominal Section, was performed by Heath (a) of Manchester, with the long incision "from a little below the ensiform cartilage to within an inch and a half of the symphysis pubis," under the supposition, that the disease was an ovarian tumour. The opening of the peritoneum, however, immediately showed its true character, and its removal was determined on. Two double ligatures were passed, by means of a sharp-pointed aneurysm- needle, through the cervix uteri, immediately below the circumference of the tumour. Each ligature was then firmly tied, so as to include one half of the neck of the womb and broad ligaments. The parts were then excised and removed. No bleeding ensued from the cut surface; in- deed, throughout the operation not more than three ounces of blood were lost; and after the division of the skin, few complaints of suffering were made by the patient herself." Soon after the operation vomiting came on with severe pain about the umbilicus, to relieve which, two grains of opium (a) London Medical Gazette, vol. xxxiii. p. 309. 1844. EXCISION OF WOMB BY THE ABDOMfNAL SECTION. 575 with five grains of carbonate of ammonia were first given, and three hours after a starch clyster with two grains of acetate of morphia. She became more comfortable afterwards, had some sleep, and the pain in the belly subsided. Twelve hours after the operation, she began to com- plain of the heat of the room; two hours after she began to sink, and continued to do so till seventeen hours from the operation, when she died. Fourteen ounces of blood were found in the cavity of the belly. This operation was commenced under the notion of the disease being an ova- rean tumour, and the large cut having been made, it was thought advisa- ble to remove the tumour though belonging to the womb.] I w 1 SIXTH DIVISION. LOSS OF ORGANIC PARTS. 2530. The loss of organic parts is either the consequence of external injury, of operations, or of destroying ulceration; or it is a congenital misformation. The means for the removal of such misformations, or for restoring the functions of lost parts {Chirurgia Anaplastica) are of two kinds, Organic Restoration, or Mechanical. Apparatus. I.—OF ORGANIC RESTORATION OF LOST PARTS. Tagliacotius, De Curtorum Chirurgia per institionem. Venet., 1597. Rosenstein, De Chirurgiae Curtorum possibilitate. Upsal, 1742. Dubois et Boyer, Dissert. Quaest., An curiae Nares exbrachio reficiendae1? Paris, 1742. C arpue, J. C, An Account of Two successful Operations for restoring a lost Nose from the integuments of the forehead ; with Remarks on the Nasal Operation. Lon- don, 1816. 4to. Graefe, C, Rhinoplastik, oder die Kunst, den Verlust der Nase. organisch zu ersetzen. Berlin, 1818; mit sechs Kupfertaf. Sprengel, W., Geschichte der chirurgischen Operationen, vol. ii. p. 185. Halle, 1819. 8vo. Grakfe, C, Neue Beitrage sur Kunst, Theile des Angesiehtes organisch zu Ersetzen; in Journal fur Chirurgie und Augenheilkunde, vol. ii. p. i. Delpech, Chirurgie Clinique de Montpellier, vol. ii. Dieffenbach, Chirurgische Erfahrungen, besonders iiber die Wiederherstellung zerstorter Theile des menschl. Korpers nach neuen Methoden. Berlin, 1829-38. Labat, De la Rhinoplastie, Art de restaurer ou de refaire completement le Nez. Paris, 1834. Blandin, Autoplastic, ou Restauration des parties du Corps, qui ont ete detruites, k la faveur d'un Emprunt fait k d'autres parties plus ou mpins eloignees. Paris, 1836. Zeis, Handbuch der plastischen Chirurgie. Berlin, 1838.. Serre, Traite sur l'Art de restaurer les Difformites de la Face selon la Methode par^deplacement ou Methode francaise. Montpellier, 1841; avec un Atlas. Dieffenbach, Operativ Chirurgie, vol. i. p. 312. von Ammon und Baumgarten, Die plastische Chirurgie nach ihren bisherigen Leistungen. Berlin, 1842. Liston, Robert, Practical Surgery. London. Fourth Edition, 1846. 8vo. Mutter; Thomas D., M.D., Cases of Deformity from Burns successfully treated by Plastic Operations. Philadelphia, 1843. 8vo. i---------------•--------, Cases of Deformity of various kinds successfully treated by Plastic Operations. Philadelphia, 1844. 8vo. [Warren, J. M., On the Autoplastic methods usually adapted for the Restoration of Parts, lost by Accident or. Disease. Boston^. 184P, 8v.q.. HISTORY OF NOSE-MAKING. 577 Pancoast, J., A Treatise on Operative Surgery. Philadelphia, 1844. 4t0.—G. W. N.] Ferguson, William, A System of Practical Surgery. London, 1846. 8vo. Second Edition. 2531. History points out the methods of organically restoring the lost parts of the face, especially of the nose, the mutilations of which disfigure most horribly, under three distinct classes. Either the neighbouring skin, especially that of a forehead, is made use of; or the skin of the arm, whilst still remaining connected with its original seat, till it has be- come organically connected with the part on to which it has been trans- planted ; or the transplantation of a completely detached piece of skin upon the part to be supplied. The ancient bad practice of restoring old divisions and clefts of the nose by drawing together their edges fresh pared and detached, to some extent, or by encouraging granulation must be distinguished from restoration by transplanting. 2532. The origin of organic restoration is lost in the earliest periods of Indian history, and appears to have been preserved from age to age in certain castes, especially the Koomas or Potters. In India, where many criminals are punished by cutting off the nose, ears, and lips, the fre- quency of such mutilations has manifestly led to this operation. The peculiarity of the Indian Method is, that the flaps of skin necessary for the restoration are formed from the skin of the forehead. About the middle of the fifteenth century, the art of restoring lost noses was found in Sicily, in possession of the family of Branca, from whom it passed into Calabria, to the family of Bojani, but with the end of the sixteenth century it was entirely lost. About the same time it was prac- tised by Caspar Tagliacozzi, of Bologna; he wrote a special work on the subject, and brought it into great repute. It is doubtful whether this operation was brought from India to Italy, perhaps by the Arabs or by the missionaries, or whether it originated in Italy itself. The characteristic of the Tagliacozzian or Italian Method, is the formation, of the restoring flaps from the skin of the arm, which, after a preparatory management, are attached to the seat of transplantation. Tagliacozzi had but few followers; his scholar Cortesi described his master's and his own some- what modified operation in 1625; Griffon performed it twice, Moli- netti once, and Thobias Fienus gave an extract relating to it from Tagliacozzi's work. For a long while after, this operation sunk into disuse, since by most people it was held to be inapplicable or fabulous, and many no longer thought about it. Yet in India it was still practised, even by an English Surgeon named Lucas, who had' learnt it from the Indian operators, and. was successful; and in England it was performed by Lynn, in 1803, and by Sutcliffe (a), though by both unsuccessfully. In 1814, however, it was first performed wTith good' result by Carpue, in two cases which he has described in his paper. In Germany,-Graefe made use of the Italian method in 1816, but subsequently the Indian mode; he also modified the Tagliacozzian operation, as had been pre- viously proposed in 1721 by Reneaulme de la Garanne (b), in which he connected the flap, formed from the skin of the arm, without waiting for the complete skinning over of the inner edge, to the refreshed stump- (p) Carpue, above cited, p. 41.. ) cutaway all the attachments of the scar and integu- ments, chiselled off the projecting part of the jaws, dissected up about two inches of the skin of the upper part of the neck, and one inch of that of the cheek, and brought the edges together with sutures and adhesive straps. The deformity was thus removed, leaving a small salivary fistula which was easily covered.] OF FORMING THE NOSE FROM THE SKIN OF THE ARM. 2549. The formation of the nose by a piece of detached skin, for which the skin on the inside of the arm immediately over the m<. biceps is best suited, is for both patient and operator a very much more trouble- some operation than the Indian rhinoplasty; it is more uncertain in its result, and better fitted for the reparation of a part than of the whole nose. The transplantation performed is either immediately after detach- ing the flap (Graefe's German method,) or after previous preparation of the part (Tagliacozzi's Italian method.) (a) Journal Clinique desHdpitaux de Lyons, No. I.—Journal Hebdomadaire de Medecine, ^ol(,viJ%p..442, l£3Pf> (6) Ibid.,.p. 442. FROM THE SKIN OF THE ARM. 589 2550. In the German Mode of Rhinoplasty^ which can only be under- taken in persons who are very healthy, and whose skin is quite sound, the necessary bandages are to be applied nightly for some time, eight days, previous to the operation, so that the person may get accustomed to them ; and every day, the part of the skin of the arm to be used in the reparation is to be rubbed with spirit, when the waistcoat must be drawn together, but the hood thrown back. The measurements for the flap of skin, and the markings on the nose-stump are to be made as described in the Indian method, excepting that the part of the flap corresponding to the septum, which runs downwards, should be about twro-fifths narrower than the wings of the nose, and should be marked of such length, that the whole flap should be one-fourth longer than the paper model. The edges of the nose-stump are to be so refreshed that the side cuts meet above ; the notch for the septum is not yet to be made. The threads for the stitches are to be introduced at the determined points. A piece of the skin of the arm is now to be separated, with as. much cellular tissue as possible, on both sides and at the upper end, and the arm having been raised close to the face, the parts, are brought together by drawing the threads through the points marked on the skin of the arm. Lint is to be put into the nostrils, and upon the under surface of the flap of skin and on the wound in the arm a pledget, spread with? rose ointment, which must be fastened with strips of sticking plaster. The arm is now to be kept in the proper nearness to the face by the connecting bandages. The general and local treatment must be conducted according to the rules laid down for the Indian method, and more especially must the patient keep his head and arm perfectly still. As often, as the lint is sopped with the pus and fluids it must be removed, and the nostrils cleansed by injecting lukewarm water. If union take place, the stitches maybe removed, though not earlier than seventy-two hours. When,the union has acquired sufficient firmness, the division of the skin fr-ora the arm must be made; and this is done, after removing the bandages, and whilst an assistant supports the arm, by making a transverse cut between the lower angles of the longitudinal cuts with a rather long, convex bistoury; after which the skin flap is kept in its proper place by the in- troduction of pledgets spread with zinc ointment and strips of plaster^ and must be covered with a layer of aromatic cotton to protect it. After about fourteen days the formation of the nostrils and septum must be undertaken, for which purpose, with the aid of the model, the position and form of the nostrils and septum is to be marked with varnish, and cut out with a narrow scalpel and Cooper's scissors, and the septum fixed into the wound made for it with, two stitches. In from three to five days, when the septum has healed, the stitches must be taken out, and the further treatment, in reference to dressing and improving the form of the nose, managed according to the Indian method. Benedict (a) has specially endeavoared to further the preference of the German method by his successful practice, and has proposed an alteration of the binding apparatus, by which it is rendered easier to change the dressings; he putsplugs into the apertures of the nostrils. (a) Beitrage zu den Erfahrungen iiber die-Rhinoplastik nuch der deutschen Methode, Breslau, 1828; with four plates. 50* 390' RAISING A SUNKEN NOSE. According to Galenzowski, the septum should be formed immediately after the separation of the flap from the arm, and fixed, at once. 2551. In the Italian Method of Rhinoplasty, the piece for the flap is marked upon the corresponding part of the arm, which, on account of its shrivelling up afterwards, should always be six inches long and four broad. Instead of the trellis forceps used by Tagliacozzi, it is better, according to Graefe, first to make the two side cuts with a scalpel, and then divide the skin from the underlying cellular tissue, with a very blunt director, a gum fleam, or even with the finger, from one side cut to the other. A piece of linen spread with rose ointment is then to be drawn by a thread fastened to its side, under the flap; the side cuts are covered with lint spread with- rose ointment, with a compress, and the whole fastened with a circular bandage. This dressing is to be first removed after three or four days, but a. fresh piece of linen is to be previously introduced beneath the flap, if suppuration be properly established. In this way, with proper modifications, according to the condition of the suppuration, and so on, the case is to be proceeded with, and then the division of the flap, at the upper end of the side cuts, must be made upon a director introduced for the purpose. The flap should not, according to Graefe, be turned baGk as recommended by Tagliacozzi,. but merely supported by a wad of charpie and oiled, pasteboard; and afterwards dressed with lead wash or decoction of elm bark. The flap always shrivels up, but gains in thickness proportionally ; and towards the sixth or eighth week, sometimes still later, though according to Tagliacozzi, in a month, becomes completely fixed. The mode of fixing the flap, and the further, treatment, corresponds with that of the German method. OF RAISING A SUNKEN, NOSE., 2552. When the bones and cartilages of the nose have been destroyed, and the soft parts remain, though sunken, according to Dieffenbach, the remains of the old. nose must be dissected in several parts, drawn up, and fixedun such way that the nose is raised up. The head of the patient must be steadied by an assistant, a narrow pointed scalpel passed into the left nostril, and the soft parts divided with a stroke in the side of the ridge of the nose up to the nasal process of the frontal bone. The same ig to be done on the right side, so that there is a strip of skin from the ridge and tip of the old nose remaining between the two side cuts, becoming narrow above, and connected with the skin of the forehead, and attached below by the shrivelled septum to the upper lip. If this be destroyed^ the flap can be raised; if the septum be shortened, it may be oasily lengthened by a cut on either side downwards through the upper lip. Some lines below the end of the first cut, the knife must be thrust, at the junction of the right nostril with the cheek, down, to the bone, and' c?arriecf through the whole of the soft parts obliquely down to the line where the floor of the nose terminates on the skin of the cheeks. The same cut is continued to the left side, and thus makes two semilunar cuts at the insertion of the wings of the nose, whieh pass round their.lower part outwards and upwards into the former- cut. These side flaps- are RAISING A SUNKEN NOSE. 591 now carefully divided from the bone, so that they may be raised and turned backwards. The skin of the cheek next the nose is then to be separated to the extent of three or four lines from the bone, so that it can be slipped towards the middle. The edges of the middle flap are now cut with scissors, in such way that its inner surface will be narrower than, but not separated from the epidermal side, for the purpose of giving the flap the form of a keystone of an arch. The edges of the wings of the nose are to be cut in the contrary direction, so that a strip as thick as a straw may be removed from the upper surface, leaving the inner surface untouched. After carefully cleansing the wound from, blood, the parts are brought together with twisted sutures, of which the lowest should be by the side of the tip of the ndse. Around that part of the upper lip from which the septum has been taken, a: ligature must be passedj and so placed behind it as to draw it and the tip of the nose forwards, and prevent its reunion in the old groove. The junction of the side edges of the nose with the skin of the cheeks is effected with four interrupted sutures. Lastly, two long pins are carried through the edge of the separated skin of the cheeks behind (on each side of) the nose, through strips of stiff leather, which are pressed together on the one side by the heads of the pins, and on the other, by twisting their points spirally with the forceps, by which the nose is permanently projected. The after-treatment is conducted accord- ing to the rules laid down for the Indian Rhinoplasty. This exceedingly troublesome and very painful operation rarely answers expectation, as according-to my own experience, although the nose remains for a time after the operation pretty well, yet subsequently, it again shrinks. For this reason, Dieffenbach^ thinks it preferable, in most cases of flattened-nose, to insert a strip of skin, which may after- wards be partially removed (a). [Liston's treatment of this deformity is much more simple. He observes:— " Sometimes the cartilaginous portions of the nose fall a prey to abscess andulceration, while the integument remains intact, excepting the column, which usually shares the fate of the cartilages. The consequence is a sinking down into the nasal cavity. The depression may be obviated by simply raising the parts after dividing any ad~ hesions that may have formed in their new situation. By stuffing the nose carefully and neatly, the integument is retained of a proper shape until the disposition to fall in is in part overcome, and firmness and stability obtained. Then a new columna is raised and fixed, and careful stuffing of the nostrils is continued until all has become consolidated." (p. 264.) Fergusson's- (b) method differs from Liston's, in not making use of stuffing and in supporting the cheeks. He "introduced a scalpel into the opening in the nose, and dissected the sunken alae from their attachments underneath, then raised the cheeks for more than half an inch from the surface of each upper maxillary bone, and cut to such an extent as to allow, when the finger was introduced-under the nose, to raise and put it into a shape somewhat like the original. He then passed two silver needles, armed with steel points, and provided with small round heads, from the left cheek to the right, under the nose, and through those parts which had been dissected from the bones. By means of two pieces of firm leather, two inches (a) Dieffenbach, above cited.—Rust, Michaelis, Ueber die Herstellung der nor- Neu;: Methode, verstUmmelte und durchbro- malen Form eingefallener Nasen mittelst chene Nas n auszubessern; in his Magazin, des Vorziehens ihres flbrig gebljebenen vol. ii. part iii.—.Wattmann, Ueber vefkrup- Theiles; in von Graefe und von Walther's pelte Nlsen und deren Fonnverbesserung; Journal, vol. xii. p. 291. in Beobachtungen und Abhandlungen von (6) Edinburgh Medical and Surgjcal dem Dir.u. Prof, des Studiums der Heilkuude Journal, voL xTiii. p, 363. 1835* an der Universitat.zu Wien, vol. vi. p. 433.-— 592 RAISING A SUNKEN NOSE. long by one-half broad, through which the pins were also passed, he was enabled on twisting the extremity of each pin spirally, after having cut off the steel points, to bring the cheeks near to one another, and in this way to cause the nose to become prominent. On the eleventh day he withdrew the pins, and introduced two others at different points from those first used; and in eight days more, on these being removed, the nose stood quite prominent."] , 2553. If the bridge of the nose drop in, as consequence of destruction of a part of the septum, but the bony frame still remain perfect, accord- ing to Dieffenbach, a wedge-shaped piece should be cut out of the pre- viously long and down-hanging nose. The tip of the nose being stretched, the straight edge of a knife is placed upon the ridge of the nose below the nasal bone, and the nose is cut through at a stroke, with the blade turned a little upwards, to the skin of the cheek. A like cut is then made obliquely upwards beneath the depression, so that both cuts meet at an angle, and cut out a wedge-shaped piece. When the usual smart bleeding has ceased, and the secretion of lymph into the wound has be- gun, two interrupted sutures are passed with round needles through the septum, one end of each thread cut off, and the other carried to the nos- tril. The edges of the wounds on the sides and ridge of the nose are to be united by six or eight twisted sutures. With a small, straight-pointed nose, which by cutting out a wedge- shaped piece, would be drawn too much upwards, on each side two semi- circular cuts must be made, so that the one point of the oval turn to the ridge and the other to the base of the nose. The union of the septum and of the outer edges of the wound are made as in the former case. After the operation a little bump is formed on the ridge of the nose, which at a later period becomes level. In other cases the ridge of the nose may be preserved, and merely an oval piece cut out of both side walls, so that one point of the oval turn towards the cheek, and the other to the ridge of the nose. The union is managed as before. Here also must be mentioned the inhealing of metallic frames and plates of gold or platina, for putting to rights sunken noses, as has been attempted by Rust, Klein, Galenzowski, and Tyrrell. Although the inhealing readily take place, yet the plate must most commonly be removed afterwards. [I recollect Tyrrell's operation with a silver frame, which consisted of a long narrow silver stem for the ridge, terminating below in three prongs, which were bent so'as to support the column and wings of the nose, to which it at once gave an excellent form. Its subsequent removal, for what reason I do not recollect, was at- tended with much difficulty; and, if my memory be correct, the nose which had been made with a flap, dropped down and was not very ornamental.—j. f. s.] 2554. If the tip of the nose be turned too much downwards, as in double hare-lip and wolf s-jaw, and depend on a folding of the cartilagi- nous septum, the nose may, according to Dieffenbach, be raised by cutting through this fold. The skinny septum is to be taken hold of and drawn aside till the fold appears, which is then to be pierced with the point of a small scalpel, and cut through to the root of the bony septum. The tip of the nose immediately rises of itself, and still more if it be raised. Compression of the sides of the nose is to be made with leathern or leaden splints, through which long insect-pins are to be thrust across the nose, and pressed together by rolling up their ends; or a saddle- shaped plate of lead is to worn on the nose. [ 593 ] II.—OF THE MECHANICAL COMPENSATION FOR LOST PARTS. 2555. The compensation for lost parts by mechanical contrivances is either merely with the object of removing or diminishing deformity, or for restoring the functions of lost, parts ; the former is the object of artifi- cial noses and eyes, the latter of artificial legs and the like. A.—OF ARTIFICIAL LEGS. 2556. The oldest and most simple contrivance for the purpose, after the loss of the thigh or leg, of rendering the mutilated person capable of walking without crutches, is the wooden leg, {die Stelzen, Germ.; jambe de bois, Fr.,) which, though it do not hide the deformity, still, especially with some practice by the cripple, answers its object tolerably well. For the purpose of not merely supplying the lost function of walking, but also of giving, as far as possible, the form of the lost limb, a multitude of contrivances have been proposed, from Pare up to the present time. 2557. Pare {a) gave an engraving of a machine for the amputated thigh which was furnished with a knee-joint, and with joints in the fore part of the tarsus, and with an elastic spring. Ravaton (b) invented artificial legs for those who had lost their leg immediately above the ankle.. White (c) describes artificial tin legs covered with thin leather. Addison {d) invented an instrument with motion at the knee, and ankle- joints. Wilson (e) formed legs of stiff leather. In Germany Brun- ninghausen {f) made known an artificial foot, which wTas far more perfect than the old ones, and gave pattern to those of StAh (g), Berrens (h), Heine (i), Graefe (k), Ruhl (I), Palm> (m), Dorn- bluth {n), and Schuruchat, for the thigh, and Wals (o), Miles, Serre, and others, for the leg. 2558. In making choice among the different kinds of artificial legs, the following points are to be attended to ;—Besides the correspondence of the artificial with the whole leg as to form, for the purpose of removing the deformity, it must be made as light as possible, but proportionally strong; it must allow the natural movements; and afford a convenient (a) QSuvres, p. 904. Paris, 1798* Fusses, fur den Ober. und Unterschenkel. (b) Chirurgie d'Armee, &c. Paris, 1T68. Wurzburg, 181-1. 8vo. (k) Nonnen fur die Ablflsung grosserer (c) Bfll, B., System of Surgery, vol. vi, p. Gliedrnassen, p. 1"47. Berlin, 181.1. 512. (.1) Ueber die Ersetzungs Chirurgie im (d) Bromfield, William, Chrurgical Ob- Allgemeinen, nebst Abbildung und Besch- servations and Cases. 2 vols. 8vo. London^ reibung eines kiinstlichen Unterschenkels; 1773. in Hufeland's Journal, vol. xl. part iv. p. 1, (e) Bell, B.,above cited. fig. i.-viii. 1818. (/) Ricrter's Chirurgische Bibliothek^ (m) Dissert. (Pries. Autenrjeth) de pedi- vol. xv. p. 568, fig. i.-iv. bus artificialibus. Tubings 1818. (g) Anweisuny zuai verbesserten chirury. (n) Ueber den Mechanischen Wiederer- Verbande, p. 498, pi. xxiv. fig. 2^27, 228. satz der verlorenen unteren Gliedmaasen Berlin, 1802. durch eigene Apparate. Rostock, 1831; (h) Langenbeck^ Bibliothek der Chi- with two plates. rurgie, vol. iv. p. 173, pi. i. fig. i.-iv., pi. ii. (o) Rust's Magazin, vol. kii. part hi.— fig. i. ii. Riss winkler, A., Ueber kunstliche Fiisse. (j) Beschreibung eines neuen kiinstlichen Wien, 1836, fol.—Frorieps Chirurgische Kupfcrtafeln pi. ccccli. 594 ARTIFICIAL LEGS. and safe rest for the stump which it surrounds, avoiding, however, all painful pressure on it, and especially on the amputated surface. Simpli- city of construction and lowness of price are, at least for the greater num- ber of maimed persons, important advantages. Of all the artificial legs proposed, those which best answer these acquirements, according to my experience, are Ruhl's for the leg and Stark's for the thigh. 2559. Ruhl's leg has the peculiarity of well-stretched Russia leather, two inches broad around the stump, to which two strong brass hooks are attached; with this the stump received into the socket of the leg is suspended, and so fastened that the amputated surface is not subject to any pressure. The leg is connected by a joint to the foot-piece, and this in like manner to the toe-piece. At the upper part of the leg, on both sides, are two wings fixed with hinges, which are applied on both sides of the thigh, and drawn to with a strap. The whole leg is made of lime- wood, properly hollowed, having been previously sawn through for that purpose, afterwards glued up, surrounded with a bandage dipped in glue, and afterwards lacquered. 2560. Stark's thigh consists of a thigh-piece, made of copper or tin, for the reception of the stump; of a knee-piece and leg, composed of soft but tough wood, and connected by a hinge; and lastly, of a foot- and toe-pieces. The fastening of this artificial limb is by means of an iron rod passing up from the thigh-piece to the hip-bone, by which it is attached with a strap around the pelvis. Over both shoulders strong straps, like breeches braces descend, and are fastened behind and before to knobs with elastic springs. The weight of the whole body rests on the padded edge of the thigh-piece, so that the end of the stump lies in the cavity of the thigh-piece, softly, upon an elastic leather pad. 2561. When, after amputation of the leg, the stump becomes per- manently bent, or where it has been so bent by anchylosis of the knee- joint, then, only, a wooden leg can be used. This consists of a lower portion turned cylindrically, upon which an upper piece hollowed in an oval or semicircular shape rests, from which two splints an inch and a half wide rise up on the thigh, the outer to the hip-joint, and the inner to the middle of the thigh. These splints are fastened by straps to the thigh, and from the upper end of the outer another strap passes round the pelvis. I have in many instances extended the long splint only to the middle of the thigh, making it, however, so elastic, that by means of straps it may be brought quite close to the thigh, by which the leg is rendered much lighter and more convenient (a). Ruhl (b) has made a wooden leg, in which with motion at the knee-joint, the stump is fastened in the same way as with artificial legs, and the maimed person is capable of moving the knee-joint. 2562. For the thigh, that wooden leg is best in which Stark's socket for the stump of the thigh is fixed upon the cylindrical lower piece, and its firm application is in this way as in an artificial leg ef- fected. 2563. The wooden leg has always the advantage of simplicity, less price, firmer application, and greater lightness. In the leg, the back- Co) Brunninghausen's Wooden Leg, above cited, pi. iii. (b) Abqve cited, part v. p. 108, fig. i.—iv. ARTIFICIAL UPPER-ARMS. 595 ward bent stump, if not too long, rests easily, hidden with a rather wide stocking. For poor persons, especially of the labouring class, a wooden leg always answers best. I have often seen rich persons, after trying various kinds of artificial legs, given them up for a mere wrooden leg. 2564. After amputation between the astralagus and os calcis and na- vicular and cuneiform bones, the supply of the mutilation is readiest; as in most artificial feet, two foot pieces,' properly hollowed and padded behind, so that the scar of the stump cannot be pressed, are made use of. The whole is put into a boot or leathern stocking, which is drawn to- gether and fixed to the knee {a). When in this case the calf has consi- derably shrunk above, it is necessary that the foot-piece should be so fastened to the heel, that in walking the heel should be a little pulled down. B.—OF ARTIFICIAL HANDS. 2565. In Pliny (6) is found an example of the replacement of a lost hand by an iron one. The artificial hand of Gotz von Berlichingen is well known, and its mechanism has been described and engraved by von Mechlin (c). Pare {d) has given plates of artificial hands made of iron and boiled leather. Wilson (e) also manufactured them from leather. Ballif {f) of Berlin devised a contrivance more simple than von Berlichingen's, by means of which without the assistance of the other hand, flexion and extension could be performed at will, so that objects could be held firmly, and even a pen taken up and written with. Bending the fingers is effected with elastic springs, and straightening with catgut, by bending and straightening the arm. For the application of such artifical hands, it is always necessary that there should be a suf- ficient stump of the fore-arm. C—OF ARTIFICIAL UPPER-ARMS. 2566. When sufficient stump is left after amputation, Graefe {g) thinks that it may perhaps be supplied, as well as in lost fore-arm, by an artificial hand, which must also have an artificial elbow-joint. The upper-arm must be surrounded with a sheath, from whence spiral springs pass to the fore-arm to effect the bending of the elbow-joint. Catguts fixed upon the opposite side, pass from the upper and hinder edge of the fore-arm to the arm-pit pieces of the chest-strap. If the arm, by bending the stump, be brought towards the chest, the fingers also by means of the springs, remain so. If the stump be carried away from the chest by means of the stretching of the catguts, the elbow-joint, and also the fingers, are straightened. (a) Graefe, above cited, p. 155. (e) Bell, Benj., above cited, vol. vi. p. 513. (6) Historia Naturalis, lib. vii. cap. xxix. (/) Graefe, above cited, p. 156-164, pL (c) Die eiserne Hand des tapfern Ritters vi. fig. i. ii.—Geissler, Beschreibung und Gotz von Berlichingen, u.s. w., beschreiben Abbildung kiinstlicher Hande und Arme, und abgebildet von Ch. v. MecheLn. Berlin nebst einer Vorrede von Joerg. Leipzig, 1814. 1817- (d) OZuvres, pp 902, 903. (g) Above cited, p. 164. [ 596 ] D.—OF ARTIFICIAL NOSES AND EARS. 2567. If the organic reparation of the nose be impossible, or be not eff'ected, there remains only its replacement by one made of silver plate, of lime wood, papier mache, and the like, to hide the deformity. It is evident that such nose should be made to correspond as well as possible to the form of the face, and should be coloured externally to match. The fixing of this kind of nose, if only a small part of the original one be lost, is effected by smearing sticking plaster on its inner surface, or by springs in the nostrils, or by little bandages drawn through the nostrils into the mouth, and attached to the teeth, or what is best by a spring passing from the root of the nose over the temples to the back of the head. If the mutilated person wear spectacles with his artificial nose, the decep- tion is very complete (a). 2568. Artificial ears are best made of silver, and fastened by a tube passing into the ear passage, and a spring passing round the head. E.—OF THE SUPPLY OF LOST PORTIONS OF THE HARD PALATE. 2569. Openings in the hard palate are either vices of the first forma- tion, as in wolf's jaw, or they are consequence of destroying ulcerations, specially those from syphilis. A piece of sponge, corresponding to the opening in the palate, attached to a silver plate, fills up the space, and thus the loss of speech and difficulty of eating and drinking are got rid of. Such instruments are called obturators; and it must be remarked, that there should not be too great hurry in having recourse to them, as both congenital clefts of the hard palate, as well as those produced by ulceration frequently contract and close of themselves, which process is prevented by the introduction of a foreign body. The obturator must be occasionally removed, cleansed, and replaced with another. F.—OF REPLACEMENT OF THE TEETH. 2570. It has been already remarked {par. 896) that a tooth which has been drawn, if it be at once replaced in its socket, and the jaw kept quiet, most commonly becomes fixed, hence in former time arose the objectionable and inhuman practice of transplanting teeth. 2571. For the supply of lost teeth, others taken from the dead body, and properly cleaned, are used; these are inserted into the gaps of the teeth which have been drawn, and are fixed with silken or golden thread, to the neighbouring teeth. Or artificial teeth are manufactured from hip- potamus' teeth, from ivory or bone, and from enamel. If the tooth- socket be already Closed, or very much narrowed, the crown only of an artificial tooth can be fixed upon the gum, and fastened to the neighbour- ing teeth. When the crown of a tooth is bad, but its root still remains firm, the crown must be filed off and another attached on the remaining root by means of a stem; or an artificial tooth may be fastened with springs td the neighbouring teeth. (a) Klein; in Heidelberg, klinisch Annalen, vol. ii. p. 103. [ 597 ] SEVENTH DIVISION. SUPERFLUITY OF ORGANIC PARTS. 2572. To this division belong few subjects, to wit, first, supernumerary fingers and toes; secondly, supernumerary teeth; and, thirdly, doubled teeth. I.—OF SUPERNUMERARY FINGERS AND TOES. 2573. Supernumerary Fingers occur under two different forms. The supernumerary finger is either articulated with the metacarpal bone of the thumb, of the fore, or of the little finger; it resembles the other fingers in form, but is not provided with proper motive organs ; and by its growth interferes with the motions of the neighbouring fingers. Or, it is not merely a supernumerary finger, but there is also a supernumerary metacarpal bone, and the finger has its perfect organization and mobility. The same applies to supernumerary toes. 2574. In the first case the removal of the supernumerary finger by dis- jointing it from its connexion with the metacarpal bone is indicated. In the second, disjointing the finger is of no use as regards the deformity; the metacarpal bone must also be removed. Such finger may be useful by its free motion and perfect organization. II.—OF SUPERNUMERARY TEETH. 2575. Two conditions are observed with respect to these. Either a milk-tooth remains firm, and that which should have its place grows in some other direction, and penetrates through either the outer or inner surface of the alveolar process; or, in consequence of disproportion between the extension of the alveolar process and the breadth of the teeth, single teeth project, either obliquely or thrust through the fore or hind surface of the alveolar process. In the former case the unnatural direction of the second tooth does not seem to depend always upon the obstruction of the milk-tooth, as it is often observed when the milk-teeth loosen. 2576. Teeth standing irregularly, cause, intheir further growth, con- siderable deformity, thrust out the lips, or irritate the tongue, and pro- duce ulceration. It is usually advised to draw those milk-teeth which prevent the proper development of the second teeth and to bring the latter into their place by pressure. But that this should succeed, the partition which separates the milk-tooth from the other must not be very thick, the unnatural direction not very great, and the breadth of the second tooth not excessive in proportion to that of the first. If this be the case, and Vol. hi.—=-51 598 DOUBLE NOSE. the first tooth be quite firm, it is better to pull out the wrong standing tooth, and to retain the milk-tooth. 2577. When the teeth stand obliquely from want of space in the alve- olar process, it is necessary to draw the oblique teeth, in which case, if this be done early, the other teeth usually take a proper direction, and fill up the socket of the tooth that has been drawn. III.—OF DOUBLE NOSE. 2578. Cases are mentioned as examples of double nose, in which tumours developed from the root of the nose, have the form of a second nose; or where the nose has been cleft in the middle. The former is either congenital or arising afterwards. Stout persons who live very well and drink much spirits are not very unfrequently subject to such swelling and degeneration of the noser which often acquires so great a size that the enlarged nose overhangs the mouth and covers it (1). The single remedy here consists in the removal of the swelling by tying, or by the knife, which is best. The cut must be made according to the condition of the swelling. The bleeding may be very considerable, and the actual cautery may be necessary to stanch it. In cleft nose, the parts should be attempted to be brought together with sutures and stick- ing plaster, after previously paring the edges. [(1) Hey (a) has given an account of a case of this kind, in which " the tumour extended to the lower part of the under lip; and compressed the patient's mouth and nostrils so much when he laid down to sleep, that he was obliged lo keep a tin tube within one of his nostrils that he might be enabled to breathe. He also generally wore this tube in the day time, as the pressure which his mouth and nostrils suffered ^ at all times from the bulk of his nose, rendered breathing without this instrument somewhat troublesome. * * * The disease appeared to Hey, to be nothing more than in enlargement of the common integuments of the nose. For though the latter were buried in the large mass of morbid integuments, yet when the tumour was supported he could distinctly trace with his finger the border of the cartilages." Dalrymple (b) observes:—"This disease cannot be called simple hypertrophy, since this tissue has lost its natural pliancy and natural colour ; but rather approaches to a state of elephantiasis, in which the cellularity is partially deslroyed,and a fibro- cellular structure substituted. The mass presents externally a nodulated surface of a purple, or deep-red colour, traversed by numerous minute and tortuous vessels. The larger separated portions are frequently divided from each other by deep fissures, occupying in many cases the convexities of the or/* and extremity of the nose. "Where the disease has been of long standing, the altered state of skin advances as high as the junction of the frontal with the nasal integuments, seldom encroaching much on the palpebral furrows laterally, but accompanied in the majority of instances by a wattled state of the skin of the cheek, corresponding in colour and general appearance with the tumour of the nose. The sebacious follicles are greatly enlarged, and their secretion ir not only increased in quantity, but unless extreme cleanliness is attended to, it is offensive in smell and excoriates the surrounding skin." (p. 396)] Upon this subject may be further consulted— Bartholin, Thomas, Historia Anatom., cent. i. hist. xxv. Borel, Historia et Observationes Medico-Physicae, cent. iii. obs. lxiii. Bidault de Villiers; in Journal Complementaire du Dictionnaire des Sciences Medicales, cah. xxxiii. p. 183. Klein, Ausrottung einer ungewohnlich grossen Nase; in Harless rheinischen Jahrbiichern der Medicin und Chirurgie, vol. v. part i. (a) Practical Observations on Surgery, (b) On the Removal of Morbid Enlarge- illustrated by Cases, p. 355. London, 1810. ment of the Integuments of the Nose ; in 8vo. Second Edition. Medical Quarterly Review,vol.i. p. 395. 1834. [ 599 ] EIGHTH DIVISION. L—OF THE ELEMENTARY PROCEEDINGS OF SURGICAL OPERATIONS. 2579. There is scarcely a Surgical Operation which can be fully per- fected on a diseased body by one single, simple act. All rather consist of several manoeuvres following, according to determined rules, and dis- tinguished by the name of Steps of the Operation (Operationsacte, Germ.) One of these is the special object of the operation, and the others must necessarily precede or follow, to effect this object, and bring about the restoration of the patient. The object of the operation is always the same, but the manner and way of attaining it may be very different, and this difference may consist either in the difference of the several steps of the operation, or of the entire way by which the attainment of the object of the proposed operation maybe effected. Hence arises the distinction between Operative proceedings and Methods of Operating. 2580. The Method of Operating is the compass of the regulated modes of proceeding, by which the object of an operation in any peculiar way is attained. In the various methods of operating, therefore, not merely are different parts cut through and in very different directions, but the prac- tice of the methods of operating is so peculiar, that the one method does not exclude the other. 2581. Upon the choice of the method of operating depends for the most part the successful or unsuccessful result of the operation, just as upon the choice of the operative proceedings rests the facility of its exe- cution. The choice of the mode of proceeding is therefore of little con- sequence, and depends commonly upon the operator himself. Hence also, the variety of opinions as to the preference of the mode of proceed- ing in general is greater than upon that of the method. 2582. In deciding upon the preference of the various methods of opera- tion the following circumstances must be attended to. First. The least important organs must be injured, consequently the loss or destruction of organic parts caused by the operation, the pain, and the traumatic reaction depending thereon is least. Second. The better method must always be most fitting for the greater number of cases. Third. This must'consist in the manoeuvres, which do not make the operator dependent on acci- dental circumstances, but which rest completely on the will of the operator. Hereon and upon the nature of the parts to be wounded, are founded safety and facility in the execution of the method of operating. Fourth. The quickest cure which can be effected by the operation. 2583. Many operations are subject to certain and general rules, and 600 ELEMENTARY PROCEEDINGS. but few cases require any variation in the way of their execution ; to these belong, for instance, all amputations, the operation for the stone, laying bare arteries, and so on. Such operations may therefore be perfectly learnt by due practice upon the dead body. There are, however, on the contrary, other operations, and their number is the more considerable, which cannot be subjected to such definite rules, and of which the con- duct must necessarily rest on the special difference of the case, and of the existing circumstances. These operations are the most difficult and require the closest knowledge of pathology, in order to be at the moment in a condition properly to comprehend and decide on the circumstances which present. Here belong, for instance, the operation for strangulated rupture, disjointing, cutting off the ends of bones, removal of tumours which are of considerable size, and seated in the neighbourhood of parts that dare not be wounded without the greatest danger to the patient. The difficulty of the operation in other respects depends on many par- ticular circumstances, and is not always connected with one and the same act of the operation. 2584. Operations are specially called for, when the cure of the case cannot be effected by any other mode of treatment. But as whatever acts upon the material side of the constitution also effects the dynamic side and influences the reaction, and as the disease^ which is hoped to be removed by the operation, is in many cases, merely the result of general persistent causes, hence must be borne in mind the various circum- stances in reference to the successful result of the operation, which depend on the method of operation, the circumstances affecting the opera- tion which relate to the condition of the patient, to the external circum- stances under which the operation has been determined, and to the possibility of good previous and after treatment.. 2585. That the operation should have the probability of a successful result, the following circumstances must be attended to: Firsts The disease to be removed by the operation, must not be so connected with any general ailment, that may act on it as a cause to keep it up continually. In such case the operation would remove merely the product of the general disease, not the producing and sustaining cause. But not unfrequently a general disease terminates in a local disease, and the operation then has the happiest result, because it gets rid of the resi- duum morbi. In these cases a careful discrimination is necessary in order to determine which of the general symptoms are to be ascribed to the reaction of the local disease, or to a persistent general cause. Second. The patient's weakness must not be great, nor the sensibility so excessive that the effect upon life resulting from the operation should bring it into very great danger. Third. The local disease, to be removed by operation, must not by its long continuance or other circumstances, be so related to the constitution, that it have acquired the rank of a secreting organ,.©)? have removed any previously existing disease, or have checked it in its earlier develop- ment. Although the above circumstances generally contraindicate an opera- tion, there may be still some cases where in spite of the decided pros- pect that no cure can be effected by operation, yet it may be employed OF SURGICAL OPERATIONS. 601 as a palliative, if it be possible thereby to mitigate the sufferings of the patient, and lengthen his existence. 2586. In regard to the patient's condition it must be observed, that operations on persons who can bear pain quietly and patiently, are less dangerous than in those who are much excited by the least pain. Those patients who have suffered severely for a long while, have become accus- tomed to pain and are enfeebled, generally bear operations best, which depends partly on the moral influence of their earnest desire for the operation, and partly on the less degree of traumatic reaction. Persons of sanguineous temperament who seem to superabound with health, are unfavourable subjects for important operations. In like manner also, very stout persons of tall and strong make. Among nervous subjects a distinction must be made between those who are very sensitive and excitable, and those who on the slightest cause drop into moral des- pondency and nervous stupidity. The former are much affected by the pain of an operation, but on account of their easy excitability, they quickly again perk up, and are influenced by encouragement and comforting hopes, so that their spirit is again aroused; but such is not the case with the latter, who writh dull despondency and nervous stupidity allow every thing to affect them, and without a murmur give themselves up. Young persons bear operations better than old ones; but even much advanced age does not contraindicate them; operations oftentimes do so much the better on account of the less degree of traumatic reaction. In gouty sub- jects operations ard always dangerous; preparatory treatment, especially purging, is necessary in such cases. It must be noted especially in scro- falous subjects, whether there be not any particular organ as the lungs for example affected with that disease. Not unfrequently; after the removal of a diseased part, scrofula breaks forth in the internal organs (a), 2587. From the circumstances already referred to* it may be for the most part ascertained u.ider what circumstances it is necessary to prepare a patient specially for an operation, as according to his different condition such remedies must be previously employed, as either counteract the general disease, raise the patient's powers, or lower the increased sensibility, or by artificial evacuations, by issues and'the like, render the result of the operation more safe. Very robust, fulKblooded persons should for some time previously be put on spare diet; and bloodletting had recourse to if the general condition should seem to require it. 2588. The practitioner must determine, according to the patient's character, whether he may venture to make him acquainted with the more immediate circumstances of the operation, or conceal them from him. With sensitive persons he must go- very cautiously to work; a kind and sympathizing carriage and encouragement, are often exceed- ingly advantageous. Great sensibility must be somewhat repressed by opiates, and in such persons-small doses-of opium before and early after the operation are required. [As a general rule, the administration of bpiirnvor any other sedative, either before er after an operation should be carefully avoided, as it is difficult and often impossi- ble to distinguish between the effects of the medicine and the symptoms springing out of constitutional excitement. Persons who have been long in the habit of taking (a) WARimorTLectures on Surgery; in-Lancet. 1932-33; vol. ii. pu51T; 51* 602! ELEMENTARY" PROCEEDINGS opium to alleviate their pain, should not be deprived of it either before or after the operation, but great care should be taken to watch the period when it can be diminished, or completely withdrawn without disadvantage to the patient; and beyond all doubt this may frequently be done greatly to his benefit much more speedily than is in general believed. Many persons who have for a length of time suffered the excruciating tortures of ulceration of the cartilages of a joint, and not known an hour's rest for weeks, will enjoy quiet tranquil sleep the first night after the removal of the limb, without any other opiate than relieffromthe horrible pain that they had previously suffered, and will need no sedative during the whole course of their cure. The same also happens frequently with hectic cases after compound fracture. I have witnessed this state o£ things so frequently, that even if opiates have been previpusly, taken, I endeavor* to do without them; and if towards night the patient drop off to sleep, none is given; but if he be restless and uneasy, opium must be given, and in such dose as shall ensure sleep, and if one be insufficient, a second should be given a few hours after, which is- asually effective. Also if, on the evening after the operation, the patient should be restless or even only wakeful, although he have not been accustomed to opium, it should not-be spared, as it is of the utmost importance to his well-doing that he should get- sleep for the first few nights after the infliction of so severe-an injury as an amputation. As to the seda- tive to be employed, opium is, I am sure, the most effective; in ordinary cases, its- tincture, from thirty to forty drops at a dose, as may be, is sufficient; but some- times, especially to free livers and sottish persons, it will ba advantageous to give it in form of muriate of morphia, a third on half a grain at a dose, and such persons not unfrequently require it twice or three times a day during the whole course of their cure. Care, however, must be taken that the bowels should not be blocked up and loaded, as not unfrequently happens, and is best corrected by a dose of three or four grains of calomel, which in general answers sufficiently, without disturbing the alimentary canal, andioxciting diarrhoea, as other purgative remedies too frequently do. Another very important point in the treatment of operations, is the use of porter, wine, or spirituous liquors; even where the patient has been prudent and temperate, it is occasionally necessary that one or other of these should be given soon after an ope- ration. But for persons who have been accustomed to take large quantities cf por- ter or spirits, or both, and who, in consequence of severe accidents, are subjected to the amputation of a limb, or who have severe lacerations, which, however, do not require operation, it is absolutely necessary for their safety that the stimulant should not only be not entirely withdrawn, but even somewhat very near the quantity they have been accustomed to, must be allowed, or they either sink at once, are attacked with erysipelas, or are violently affected with delirium tremens, in which condition they speedily die. The quantity taken may often seem enormous under the circum- stances.; three or four glasses of gin or brandy, and as much or more wine, and some- times porter besides, in the course of the twenty-four hours, is by no means an unfre- quent allowance; and I have just the recollection of one of the younger Glixe's pa- tients, a porter at the Royal Exchange, who required a pint of brandy daily alter having suffered amputation of his leg for an accident. This man was saved by this treatment, and lived many years after, doubtless following the same free course of living which had required treatment, at that period thought exceedingly bold and almost marvellous in its result, although ati present every day's practice and no wonder at allow*, f. s.] 2589. In regard to the time of year when an operation should be un- dertaken, there is no longer any restriction, as was formerly the case with many operations. If spring have any preference over.olher seasons, it depends only on the steadiness of the weather. In other respects, it the circumstances of the case allow the operation to be deferred, in those operations, which, on account of their precision require bright light for their performance, and in persons who are subject to rheumatic and gouty affections, and are very sensible to changes of temperature, a bright day, and a season when steady weather may be expected, should be preferred. The time of very oppressive heat should be, if possible, avoided. 2590. In order to lessen the pain in operations, besides moderate doses OF SURGICAL OPERATIONS. 603 of opium previous to the operation, it has also been advised to warm the instruments (a). Wardrop (6) has even proposed bleeding the patient to faintness previous to any important operation, and during the swoon to perform the operation ?! [It is scarcely possible to imagine any one could have made so precious a propo- sition as that last referred to, unless the operator's object were to finish his patient. Another more recent foolery, with the same intent, is mesmerism, which, however, does not endanger the patient as- Waadrop's proposal most certainly would.— j. f. s.] 2591. Among the most serious occurrences during an operation, be- sides severe bleeding, the following must be notieed ::— First. Faintings and convulsions,, wrhich depend either on loss of blood, on want of blood: in the brain from irregularity of the circulation, on from reflected activity of the spinal marsow, consequent on the severity of the pain. In all these cases the operation must be suspended, the patient placed in the horizontal postune, and roused by sprinkling the face-with. cold water, by scents, especially liquor of caustic ammonia, or naphtha, and according to eircumstances, reviving remedies, as Hoffman's spirit ©f aether, wine, brandy, and the like, or some laudanum should be given. Second.—Sudden death, which may indeed be the result of very severe- gain, or of loss of blood, and especially of the entrance of air into the veins. This last accident is moce frequent, and more especially occurs when large veins, particularly those of the neck and armpit, are much; pulled and dragged before being eompletely cut through. There is then heard at the moment the vein is cut through, a whizzing as on opening the air-tube, {gfiick-gluck geramch,) and immediately after-, shivering,. swooning, convulsions and death. The cause of the sudden death is the entrance of the ai» into the right side of the hea-rt, by which its move- ments are suddenly stopped. The wounded vein must be dicectly pressed with the finger, and according to Amussat, the chest and. belly quickly and forcibly compressed during expiration, and at every interval of such compression, the finger applied? to the opening of the vein, and then the vein tied or twisted. Others have recommended blood-letting by opening, the temporal artery, sprinkling with cold water, applications-of ammonia and camphorto the nostrils, andlpfessure on the abdominal aorta and both axillary arteries, as well as drawing out the air which has entered the vein through, a pipe with the mouth, or by means of a syringe and flexi- ble catheter (Magendie.) In but few instances has the patient been re- covered. It must not, however, be forgotten that many cases-which have been ascribed' to the entrance of air into the veins, are very problemati- cal, and that death must be attributed to other causes. Bichat asoribed death from the entrance of air into the veins, to its-effeot upon the brain; Nisten and Magendie to the extension of the heart; and Piedagnel (c) to emphysema of the lungs. Amussat (d)'att9mpted to restore several animals destroyed by the entrance of air into the veins, aa already described; Ji Warren (e) relates two cases, in the first of (a) Faust und Heinolo, Ueber die An. (d) Mem.de l'Acad.. Roy..de Medecine, wenrlung und den Nutzen des Oels und vol. v. p. 82. der Warme bei chirurgischen Operationen, (e) American Journal of Medical Science, Leipzig-, 1806. and article Air,-.in the American Medica! (/>) Lancet, just quoted, p. 597. Cyclopedia, vol. i. Pbilad. 1834. (c) Magendie, Journal de Physiologic, vol. ix. p. 60. 1829. 604 DIVISION OF ORGANIZED PARTS. which, the patient was restored bybleeding from the temporal artery. Mussev (a) brouo-ht the patient to himself by the application of ammonia and camphor to the nostrils. Mercier (b), who attributes-death from admission of air into a vein to the same cause which produces syncope, namely, the deficient supply of blood to the brain, recommends, that the small quantity of blood which—in spite of the obstacle offered by the admitted air to the transmission of the Mood from the right to the left side of the heart and thence to the body—is, nevertheless, transmitted into the arte- rial system, should be directed towards the brain, and this by compression of the abdominal aorta, and of the two axillary arteries. [Bransbv Cooper (c) relates a case in which this alarming syncope occurred, after an amputation at the shoulder-joint, and whilst he was removinga small gland. Whilst recovering, the patient " uttered a continual whining cry, and maintained a constant motion of alternate flexion and extension of the right leg, whilst the left remained perfectly quiet." This movement continued for about nine days and then ceased. 2592. All kinds of operations, according to their nature, must be referred to the following principal acts, which, at the same time, must be considered as the elements of every operation, and of which every single act consists:—They are, first, Division ; second, Apposition; third, Dilatation. A.—OF THE DIVISION OF ORGANIZED PARTS. 2593. The division of the connexion of organized parts, is that one of the elementary acts of an operation most frequently brought into use, and m most operations constitutes their principal circumstance. 2594. The division of organic parts may be effected by mechanical ot chemical means; though the latter is less employed in reference to division than to other objects, on whieh account division by mechanical means will now alone be considered. 2595. The parts of our body may be divided— First, By a cut or incision. Third, By tearing asunder. Sacond, By a stab or penetration. Fourth, By tying or ligature. 2596. All instruments employed for the division of soft parts by cutting must be placed in two classes; to the former belong those which have a single cutting edge, knives, bistouries, and scalpels; to the latter, those consisting of two cutting edges, connected crosswise in their middle, and terminating in handles ; such are scissors. 2597. Knives are distinguished from each other, to wit, by the fixing of the blade to its handle, and by the form of the blade itself 2598. The blade is either attached firmly to the handle, as a scalpel, or it drops into the scales of the handle andean be opened, as a bistoury. In bistouries the connexion of the blade is either such, that when opened, the blade is not fixed steady, but only cannot fall back, or the open blade may be fixed firmly. The mechanism for this purpose consists either of a metallic ring, which can be pushed up on the laid-back end of the (a) Schmidt's Jahrbiicher. No. 9; p. 332. Edinburgh, 1837—von Wattmann, Sicheres 1339. Heilveifahren bei dem schnell gefahrhches (6) Revue Medicale, vol. iii. p. 294. 1837. Lu teintritt in die Venen und dessen ge- —Amussat, Recherches sur l'lntrodnction richtsarztliche Wichtigkeit. Wien, 1843. nccidentelle de l'Air dans les Veines. Paris, (c) Med.-Chir. Transactions, voLxxviup- 1839.—Cor mack, F. C, Dissertation on the 4L 1844. presence of Air in the Organs-of Circulation. DIVISION OF ORGANIZED PARTS. 605 blade, or in a particular form of connecting stem and catch, through which it passes, so that when the bistoury is opened; the blade is^ thrust up, (Percy's bistoury,) or in a spring, like the common clasp-knife. The latter kind of bistoury is the most convenient. 2599. The utility of the bistoury depends specially on the form of its blade; the length and breadth are of less importance. The following are their distinction according to form:—*. The straight bistoury, of which the edge runs straight to the tip, which is formed by its narrowing from the back. /3. The pyramidal bistoury, in which the edge and back narrow to the point, y. The convex bistoury, of which the blade is con- vex, h The pyramidal bistoury, with a double-edged point, t. The bistoury curved, and having a button at its tip (Pott's bistoury.) The choice of these different bistouries depends upon the special use to which they are applied. 2600. In general the straight-edged bistoury is most convenient in all cases, and with it alone can a regular cut be made. A regular cut must have the same depth from its beginning to its end ; it must not have any bridges, the angles must not be cut more shallow than the middle and the edges must not be jagged. This cut is to be made in the following manner:—The ulnar edge of the left hand must be placed on the part where the cut is to be made, pressed firmly on it, and the skin tightened from above or below, and with the thumb and forefinger stretched on either side. The bistoury held in the right hand with the thumb, middle, and ring-finger, and the forefinger laid on its back, or held as a pen, has its point thrust directly down to the depth the cut is to be made, then the handle is sunk, and the whole edge is drawn with equal pressure over the parts to be cut through. When the cut has been made, the bistoury is again raised perpendicular, and cuts through every thing which still remains undivided in the angle. This is the most common kind of cut. 2601. In many cases, where the skin is easily displaced, or an im- portant part beneath may be injured, a fold of skin may be cautiously made, the one end of which is given to an assistant, the other held by the operator, and the knife drawn across its middle. Sometimes the cut is made from within outwards; the bistoury is then thrust in to a certain depth, and its edge, drawn out to or from the operator, enlarges the opening. This kind of cut has no necessary cause for its employment. It is most commonly made when the bistoury is introduced on a director. If the latter instrument be passed beneath the skin, or into a canal, it must be held with the left hand and in such direction that its end presses towards the skin, which an assistant tightens on either side, whilst the straight bistoury is rung along the groove of the director, at an acute angle with it, up to its end, when the bistoury is raised upright to divide every thing up to its tip. 2602. The convex bistoury is specially employed for making semicir- cular cuts, and for the removal of tumours, where a larger extent of blade can be made use of than with the straight-edged bistoury. The button- ended bistoury is only used when parts are cut at a depth; the bistoury may then be introduced on the finger of the left hand alone, or on a director to prevent the point doing mischief. 606 DIVISON OF ORGANIZED PARTS BY VARIOUS INSTRUMENTS. 2603. The mode of holding the knife has an important influence on its use; in this respect, four postures, or positions of the knife may be distinguished. First. The knife is held like a pen, the handle being taken hold of with the thumb and middle finger near the blade, and the forefinger laid on its back. Herewith the knife can be used with ease, and employed in every direction; it is specially suitable where small cuts are to be made with great care. Second. The knife is held with the thumb on one, and the middle and ring finger on the other side of its handle, and the forefinger laid on the back of the blade, as in holding a violin-bow. Third. The handle is placed upon the inside of the ball of the thumb, with the thumb on one side, and the middle, ring, and little finger on the other, whilst the forefinger is extended upon the back of the blade. Fourth. The knife is grasped with the whole hand, the thumb on one and the fingers on the other side of the handle; this is only applicable to large or amputating knives. 2604. Scissors effect the division of parts, like the bistoury, by drawing and pressure ; but the pressure is greater, and therefore the scissor edge is not generally so fine as that of the knife; neither are the edges set directly opposite, but lie beside each other, so that ordinarily, a cut with scissors, is not so clean as that with a bistoury; the parts must also be pressed and squeezed before they are divided. On this account the use of scissors is by many entirely rejected. The objections, however, to the use of scissors may be done away with by the proper fineness of their edge, and by the greater power with which they can be employed. It has been hitherto supposed that the due degree of fineness, Tike that of a bis- toury, cannot be given to scissors without impairing their strength. I, however, possess scissors made by our clever, instrument-maker, Gorck, which have the per- fect edge of a bistoury, and with, proper strength. 2605. Scissors are specially employed to a certain extent for cutting off disorganized parts, for instance, in torn or bruised wounds, to remove the loose flesh in misshapen flaps ; in gangrene, to take away the half- separated sloughs and the like; in very luxuriant fungous growths of flesh ; but especially for cutting off very soft or yielding parts which have no supporting point, as in cutting the frenum lingue, cutting off excre- scences from the mouth, refreshing the edges of harelip, for cutting out a portion of the thickened vaginal tissue in operating on hydrocele by in- cision, and the like. 2606. Scissors are distinguished according to their form. u. Straight Scissois, of which the blades are made pyramidal and run to a point; the point of one blade being pretty sharp, and that of the other somewhat rounded. /3. Scissors curved towards the surface of their blades, (Cooper's scissors,) or the blades curved at an angle. These are used for removing growths with necks, luxuriant granulations and the like, or when they have to act in a cavity, y. Scissors curved towards their edge in an arch or at an angle. The use of the latter (kneed scissors, or Richter's scis- sors) have the advantage of being used with more power, and their blades are not so very much drawn back in cutting (a). Besides these, there are also scissors which have a double curve, that is, towards their blades and their edges, (Daviel's Scissors,) which are used for enlarging the cut (a) Percv, Memoire sur les Ciseaux a incision. Paris, 1784. SEPARATION OF DIVIDED PARTS. 607 in the cornea in the extraction of cataract, Levret and Percy's scissors for shorten- ing the uvula have been already mentioned, (par. 133.) 2607. In using scissors, the thumb and ring-finger are to be passed into the rings of their handles, and that handle held with the fore and middle finger, in the ring of which is the ring-finger. In this way more power is gained than if the middle instead of the ring-finger be put in one ring. The blades of the scissors having been opened, and passed several times between the fingers of the left hand, the parts to be divided are made tense, and then whilst the blades are brought together, the escape of the part from them must be prevented. 2608. As regards the division of soft parts by stabbing, it must be ob- served, that all the instruments employed for that purpose, are formed to penetrate the parts in a peculiar way; consequently the wounds made by them are to be considered and treated as clean cuts. The object of a stab is the discharge of an unnatural collection of diseasedly produced or natural fluids. The instruments for this purpose are the trocar and the lancet. The trocar consists of a steel stem with a wooden or horn handle, and which runs to a point with three cutting edges, and of a silver canula which ensheaths the stem, behind the part where the three-cutting edge begins, and so ranging with it that there is not the least elevation. Two- edged trocars are inconvenient. The lancet consists of a narrow blade, with a cutting edge on either side to its tip and so connected with the two scales of its handle that it can be moved backwards or forwards. 2609. Tearing presupposes with the division of connexion, also a tearing and bruising of the part; such wounds there do not heal like a clean cut or stab. This proceeding has only the advantage of the con- sequent bleeding being less than in dividing with a cut. Hence, it is specially used for polyps. 2610. The division of parts by tying or the ligature is a slow cutting in by its firm tying, in which the divided parts heal, proportionally as the ligature cuts deeper in. This method is always tedious, painful, and should be only employed where the neighbourhood of important parts render the use of the knife dangerous, for instance, in fistulous passages and tumours of various kinds. 2611. The division of a bone requires, on account of its hardness and firmness peculiar instruments. Such are performed. «. After the manner of a ad with the saw ; with the circular saw, the trepan ; with the chissel and hammer ; with the bone-knife, and with the nippers. /3. After the manner of a stab with the perforating trepan ; and y. By scraping, either with the bonescraper or the exfoliation-trepan. B.—OF THE SEPARATION OF DIVIDED PARTS. 2612. This operative proceeding in many cases, although not the prin- cipal object, yet however is one of the principal acts of the proposed ope- ration. The division of parts happens in most operations, and the indica- tion is to bring them together again. In how many ways this may, and in certain cases should be done, has been already mentioned in consider- ing the treatment of wounds in general. T_ 603 ] C—OF THE DILATATION OF PARTS. 2613. The object of enlarging is either simply to obtain a free entrance into natural, unnarrowed openings, as for example, enlarging the mouth, the vagina and the like by dilators and specula ; or it applies to the un- natural narrowings of natural passages, and is then effected by the intro- duction of tents, or elastic bougies, which are gradually selected of larger size ; or by such substances, as by attracting fluid, increase in bulk, like sponge tent, catgut, and the like. These remedies are also often em- ployed, after previous cutting, to prevent reunion. Second Section.—OF GENERAL SURGICAL OPERATIONS. I.—Of Bloodletting. (Mstraclio Sanguinis, Lat.; die Blullassen, Germ.; la Saignce, Fr.) 2614. Blood-letting may be performed First,b>.opening a vein ) ^^ Bloodletti Second, By opening an artery, ) Third By the application of leeches, j Local BloodIetti fourth, By scarification or cupping. ) A.—OF OPENING VEINS. (Veneseetio, Phlebotomia, Lat.; Eroffnung der Venen, Germ.; Ouverture de la Veine, Fr.) Gyer, N., The English Phlebotomy, or Method and Way of healing by Blood- letting. London, 1592. 12mo. Butler, R., M.D., An Essay concerning Blood-letting, &c. London, 1731. 8vo. Wallbaum, Dissert, de Venesectione. Gotting., 1749. Dickson, Thomas, M. D., A Treatise on Bloodletting, &c. London, 1765. 4to. Bucking, Anleitung zum Aderlassen. Stendal, 1781. Wardrop, James, M.D., On Bloodletting; an account of the curative effects of the abstraction of blood, &c. London, 1825. 8vo. Hoppe, F., Die Eroffnung der Blutadern. Neisse und Leipzig, 1835. Abernethy, On the 111 Consequences sometimes succeeding to Venesection; in his Surgical Works, vol. ii. p. 133. Edition of 1815. 2615. Opening a Vein {Breathing a Vein, in our old common language) may be performed in any of the superficial veins; but usually those of the arm, of the hand, of the foot, and of the neck are preferred. 2616. At the bend of the elbow may be chosen the cephalic, basilic, median-basilic, median-cephalic, and the upper part of the radial and ulnar veins. In regard to the choice of one or other of these veins, it must be re- marked, that the cephalic vein is safest, as far as possible injury of neigh- bouring parts is concerned, but it is frequently of sufficient size to afford the quantity of blood required; the median, median-basilic, have indeed generally a large diameter and project more distinctly, but they lie in the neighbourhood of the brachial artery, sometimes immediately upon it, and BLOODLETTING FROM THE VEINS. 609 only separated by the tendon of the wi. biceps and the aponeurosis of the arm. It is therefore always, but especially for beginners, best to choose the cephalic or median-cephalic, or the median and basilic near the inner condyle of the upper-armbone, and to avoid the part where the artery is felt pulsating beneath the vein. In very stout persons the veins, although swollen cannot be seen, but only felt. 2617. In bloodletting from the arm the patient may either sit or lie. The former is best when, the patient not being very weak or confined to his bed, fainting is not to be feared, or fainting may be produced without much blood being drawn. Lying-down is best when the patient is weak, and fainting, even when much blood is taken, is desirable to be avoided. The patient stretches out his arm moderately, and the operator with his forefinger carefully ascertains the situation of the brachial artery, and of the veins at the bend of the arm. A bandage about a yard and a half long and two inches wide, usually of red cloth, is now applied around the arm, a few fingers' breadth above the bend, its middle placed on the front, its ends carried behind the arm, where passing over each other, they are again brought forwards and tied there so tightly with a knot that the return of the venous blood, but not the inflowing of the arterial blood, is prevented. If the vein do not then become suffi- ciently swollen, the skin at the bend of the arm may be rubbed with a sponge dipped in warm water, or the arm may be allowed to hang down for a time. 2618. The surgeon nowplaces himself on the inside of the arm, and the patient rests his hand on his hip. He then opens the lancet, the point of which should be neither very narrow nor very suddenly broad, places its blade at a right angle with its scales, and puts it by them between his hips, and with its point directed to the opposite side, so that he may take it again with his hand. He next places his left or right hand, according as he has to bleed in the right or left arm of the patient, upon the elbow- joint, so that he can steady the vein which he has to open, with his thumb. This being done, and the blood stroked down a few times with the unoccupied hand, he takes the lancet with the thumb and forefinger in such way that only so much of the point should project as is sufficient for the depth of the opening. The middle, ring- and little finger of the hand holding the lancet, are now placed upon the arm, and the thumb and forefinger brought to and so dropped on it, that when they are stretched out, the point of the lancet may penetrate obliquely into the vein, imme- diately on which the blood shows on the lancet-blade, and the fingers being raised, the opening in the vein is enlarged, and the spouting blood is^to be caught by an assistant in a proper vessel. The operator now passes to the outer side of the arm, supports it, the one hand being applied to the fore- and the other to the upper-arm without altering its position; or he allows the patient to grasp the end of a stick resting on the ground. [This mode of bloodletting is not the best that can be employed, and the manage- ment of the lancet is both awkward and bad, and if, as is occasionally absolutely necessary, a vein running over an artery have to be opened, the pushing the point of the lancet obliquely into the vein is dangerous, as though the vein be wide, it may not have much thickness, and its coats both behind as well as before, together with whatever may be behind, may be pierced even by the most clever operator. Vol. hi.—52 610 ACCIDENTS OF BLOODLETTING. The readiest and best method is, after selecting the vein, to grasp the fore-arm just below the elbow, with one hand, the thumb of which is to be placed firmly upon the vein, just below where it is to be opened, and which is quite sufficient to steady it. The little finger of the hand holding the lancet is then to be rested just below the thumb of the other hand, with the other fingers piled upon it, in such way, how- ever, as to leave the thumb and forefinger with the lancet quite at liberty, and above the skin, so that the point of the lancet may be capable of a swinging motion from below upwards, and then by sinking the lancet point and making it perform the swinging motion, the front wall only of the vein is wounded, and at the same time the wound in the skin being made rather larger than that in the vein, a free opening is afforded for the escape of the blood, and thus a thrombus, which is often the con- sequence of opening the vein, as recommended by Chelius, and very commonly practised, is prevented.—j. f. s.] 2619. When the proper quantity of blood has been obtained the knot of the bandage is to be untied, the wound and its neighbourhood cleaned with a moist sponge, the wound covered with the thumb of one hand, whilst with the other, a little compress is slipped from the side of the arm, over the wound, which it presses on the removal of the thumb. The compress is then steadied by putting the thumb upon it, and after bending the arm, fixed with a bandage, which is to be carried round the elbow in several figure of 8 turns. The arm is to be kept quiet. 2620. The particular accidents which may occur during the operation are, «.. A faulty stab, in which case the operation must be repeated. /3. The formation of a too small opening; the wound must then be en- larged, or another place chosen, y. Stoppage of the flow of blood, by displacement of the skin when the arm is moved into some other position; the arm must then be restored to its proper place, and be a little more bent, the blood stroked upwards, and the hand moved; or from the bandage being tied too tight, which must then be slackened ; or from the aperture being stopped up by a little lump of fat, wThich may be brushed away with the sponge or cut off; or from extravasation of blood in the neighbourhood of the wound, in which case the operation must be repeated elsewhere; or from fainting, when the patient must be revived with fresh air, sprinkling with cold water, and the like. A Severe pain from wounding a nerve, e. Wounding an artery, which may be known by arterial blood spouting out together with the venous, by arterial blood continuing to flow after the removal of the bandage, and by it not being checked by pressure below, but above the wound. The treatment in this case consists of pressure and binding up the arm as already men- tioned, {par. 386.) £. Wound of a lymphatic vessel, of a tendon, or of the aponeurotic expansion, which is only rendered apparent by symptoms which come on afterwards. 2621. The bandage must remain if it do not slip, or no particular symptoms ensue after the operation till the third or fourth day. The accidents which may occur after the operation, are, *. Bleeding, if the bandage slip ; it must be replaced. /3. Inflammation and suppuration, in consequence of inflammation of the aponeurosis, of too tight bandaging, of movement of the arm, or of the state of constitution. Perfect quiet, loosened bandage, application of compresses soaked in lead wash, soothing poultices, and if collections of pus be formed, opening them become necessary, y. Inflammation of the veins or lymphatic vessel, which, according to its degree, requires a more or less active antiphlo- gistic general or local treatment Abernethy has, in inflammation of BLOODLETTING IN THE FOOT J IN THE NECK. 611 veins, advised the application of pressure above the wound, in order to effect the union of the walls of the vein, and to prevent the spread of the inflammation. £ Severe pain, even convulsions in consequence of partial division of twigs of the external subcutaneous nerve, when the median-cephalic vein has been opened, or of the internal subcutaneous nerve when the median-basilic has been opened. In such case, Aber- nethy advises complete division a little above the wound in the vein, which is, however, rarely followed, and proper antiphlogistic and anti- spasmodic treatment may be more fitting. I have not referred to the employment of the Snapper, because on account of its uncertainty and danger, the stroke may be made too deep, too shallow, or inefficient, and the fleam be broken off; it cannot be compared with the use of the lancet, but may also be very dangerous in unpractised hands. 2622. The veins of the fore-arm are, however, to be preferred for opening when in very stout persons, those at the bend of the arm can- not be opened with certainty. But on account of the numerous plexuses of nerves surrounding them, their opening is perilous, and it is better to choose the vena cephalica or salvatella upon the hand ; the former, how- ever, has often a branch of an artery running beneath it, and the latter is very small. 2623. In Bloodletting in the foot, after putting the foot in a tub of warm water, a bandage is to be appliad as in bleeding from the arm, a little above the ankle, the foot put on the edge of the tub, and the lancet carried as already described, into the swollen vena saphena interna or parva. The foot must then again be put into the tub of water: or if a certain quantity of blood be required, it must be caught in a vessel. The dressing is to be similar to that for bloodletting in the arm. 2624. The external jugular vein is selected for bloodletting in the neck. An assistant standing behind the patient, who sits up in bed or upon a stool, holds the head with one hand, and with the thumb of the other presses the external jugular vein, whilst the operator compresses it with his left thumb at the part where the opening is to be made. The jugu- lar vein may also be compressed on the opposite side without the aid of an assistant; in doing this a compress is placed upon it above the collar- bone, and fastened with a bandage carried around the chest and back from the armpit of the other side. The vein is to be opened with a lancet from below upwards, and from within outwards, so that it may not be covered by the neighbouring fibres of the m. platysma myoides ; and the blood may be allowed to flow along a gutter-shaped piece of pasteboard into a vessel. When the dressing is applied, the compress must be removed, the edges of the wound pressed together, sticking- plaster and a compress put over it, and fastened with a bandage. B.—OF OPENING ARTERIES. (Arleriotomia, Lat.; Schlagader-Oeffnung, Germ.; Ouverlure de VArtere, Fr.) 2625. Opening an artery is only performed on the temporal; it is re- commended in severe inflammation of important organs, as the brain the eye, and the like, so as quickly to evacuate a large quantity of blood. 612 OF THE APPLICATION OF LEECHES. This operation is best performed in the following way: the pulse of the temporal artery, or one of its branches, is sought for in the temporal region: the place is to be marked with a black streak, the skin raised in a fold and cut through. The artery is then easily found and opened in a rather oblique direction with a lancet. The proper quantity of blood having escaped, the artery is to be cut through, taken up with the for- ceps and tied, and the skin closed with sticking plaster. This method is more certain than opening the temporal artery at a stroke with the lancet, and, stanching the bleeding by pressure. [Opening the temporal artery is oftentimes far less easy than might be expected, and inattention to its subsequent division frequently causes very serious and some- times fatal results. The facility with which it is found depends pretty much upon the part at which it is opened. If this be done just before and above the tragus, it is managed easily on account of the size of the vessel; but if higher, after its divi- sion into temporo-frontal and temporo-occipital, it is more difficult; the temporo- frontal branch, which is the part of the vessel commonly chosen, as it runs along the edge of the hair, diminishes quickly in its course, so that the higher it is ope- rated on, the more difficult is it to be found. If it be expected that a single blood- letting from one or both temporal arteries will alone be required, then the artery may be opened in front of the auricle, upon, or a little above the root of the zygo- matic process. But if it is likely that more than one bleeding from each vessel will be required, then it will be better to open the artery upon the forehead, which will give the opportunity of repeating the operation again and again, each time below the former one, till the root of the zygomatic process be reached. The younger Cline, used to advise that in the performance of this operation the artery should be laid bare lengthways to the extent of half an inch or an inch, that a tenaculum should be passed across and behind it, so that the vessel could be raised, more readily punc- tured, and what was 'of infinitely greater importance, more certainly divided after sufficient biood had been obtained. Inattention to the division of the temporal artery after it has been opened, is occasionally followed by a spurious aneurysm, which cannot always be managed by compression, or even by tying the ends, and patients have been destroyed by after-bleeding wearing out the powers of the con- stitution. In general, cutting the artery completely across, and the application of pressure, are sufficient; but when the vessel continues bleeding, both its ends must be tied, as the anastomosis is so free upon the head, that if only one be tied the bleeding continues. The same practice must also be followed when spurious aneurysm of this vessel occurs after arteriotomy.—j. f. s.] C—OF THE APPLICATION OF LEECHES. 2626. In applying leeches, they may be held with a piece of linen round their hind part, so that the head, which is always their thinnest part, may be directed to the spot upon which they are to be fixed. This spot must always be carefully cleaned. Some persons apply leeches in a piece of pasteboard rolled up, or in a glass cylinder. When the part permits, it is most convenient to put the requisite number of leeches into a cupping-glass, and turn it down. The Blood-Leech (Hirudo medicinalis, Lin,) is distinguished from the horse leech and the common leech, which are never so large, by six orange-coloured stripes running from the head along the back and sides to the tail. The back and sides of the horse leech are of a blackish-brown or blackish-gray colour, without any marking; the common leech is light brown, spotted with black, and without other marks. The belly of the blood-leech is steel-blue, with regular yellow spots, but the latter are often so numerous that they are mistaken for the ground colour, and the steel-blue for the spots; in rare instances, the yellow spots are entirely wanting, and the whole belly is simply steel-blue. The belly of the horse-leech is OF THE APPLICATION OF LEECHES. 613 yellowish-gray, and that of the common leech, grayish-brown. Leeches are best caught in the spring, because in winter they do not so readily find food. Rain water is better to preserve them than river or distilled water. The glass in which they are kept should not be in the sunlight, and they should especially be put in a cool rather than in a warm place. Frequently changing the water is hurtful (a). 2627. If the leeches will not bite, the part on which they are to be applied must be smeared with spittle or sugar and water, or the skin cooled with cold water, or it must be slightly scratched and smeared with the blood. Leeches oftentimes will not take, because when previously at liberty, they had sucked freely ; their belly is then full, and such should rather be chosen in which it is sunken. They are generally allowed to remain on till they drop off'; but if necessary to get them away before, they must be sprinkled with a little salt or snuff. The after-bleeding is to be kept up by bathing the bleeding parts with sponges dipped in warm water. The recommendation of cutting off the leech's tail, if it be de- sirable they should suck long, is absurd, as they soon after drop off. I have seen one leech which was uninjured, remain on six-and-thirty hours, and the blood flowed from its tail. In the application of leeches in the mouth, care must be taken that they do not crawl down and fix in the throat, or be swallowed. In the latter case, a quantity of salt and water should be swallowed, and an emetic taken. If leeches be applied in the neighbourhood of the anus, that should be stopped up with a wad of lint. [Crampton and Osborne (b) recommend the application of leeches to mucous surfaces, having first passed a thread through the animal's tail, and then directing it3 mouth by means of a probe, or channel made with card, to the part desired.] 2628. After the leeches have dropped off, bleeding may generally be kept up for some time by sponging with warm water; but if it be wished to stop it, this may be done by bathing1 with cold water and applying German tinder. Sometimes, especially with little children, the bleeding is very severe, and may easily be fatal if unattended to. The means here advised for stanching the blood are, strewing the part with styptic powders, with gum tragacanth, the introduction of a small portion of lint into the little wound, holding the skin in a fold and pressing it together with the fingers or a proper instrument, cauterization of the part with a red-hot needle, the introduction of a common sewing-needle on one side through the skin to the bottom of the wound, and out at the other side some distance from the wound and the needle, the ends of which are covered with wax, is then to have twine twisted round so as to compress the wound firmly (c). Hennemann {d) has invented a particular kind of forceps for this pur- pose. Lowenhardt (e) penetrates superficially the edges of the wound brought together, with a fine needle and thread, arid after removing the needle, ties the thread in a simple knot. If no after-bleeding ensue, the thread in a few days drops off of itself. [The employmemt of leeches in the treatment of inflammation is so commonly (a) Kunzmann, Ueber die Function der (6) Dublin Journal of Medieal Science, Laugorgane des Blutigels, dessen Anwend- vol. iii. p. 340. ung und Aufbewahrung; in von Graefe und (c) Whete; in von Graefe und von Wal- von Walther's Journal fur chirurgie und ther's Journal, vol. i. p. 185. Augenheilkunde, vol. ii. p. 262.—Schmucker. (d) Rust's Magazin, ,vol. xvi. part iii. p. Hislorischpraktische Abhandlung von medi- 375. cinischen Gebrauche der Blutigel; in his (e) von Graefe und von Walther's Jour- Vermischte Schrifte, vol. i. sect. ii.—Otto, nal, vol. xv. p. llli. Der Mcdicinische Blutigel. Weimar, 1835. 52* 614 OF THE APPLICATION OF LEECHES. unattended with inconvenience, that it would seem scarcely worth while to refer to the subject. But frequently the bleeding from the wounds caused by them is very considerable, and very difficult to stop; sometimes threatening danger from the quantity of blood lost, and occasionally destroying the patient. It is, therefore, well worthy a little consideration. Dangerous bleedings from leeches occur in adults as well as in young children. Of the former kind, are, the case of a stout country lad who died in La Charite, of bleeding from a single leech bite on the belly in twenty- five hours, related by Brichetau (a) ; that of an old woman in La Pitie, under Lis- franc (b), to whose belly leeches had been applied ; she went on well for three days, retired to rest at night apparently well, but on the following morning was found dead in her bed in a pool of blood. My friend Green, some years since, had aman in St. Thomas's who died of bleed ing from the temporal artery, which had been bitten by a leech. Of the latter kind, the case of a child of nine months, who died in a night after a leech-bite, is recorded (c). No such fatal cases have come under my own care ; but I have frequently seen the bleeding continued for several days, so as to render the patient pale as ashes, and weakened as under severe loss of blood under any circumstances. The cause of the bleedings is either from an artery being wounded by the bite, as in Green's case certainly, and probably also in Brichetau's, and in a case of bleeding from leech-bite on the temple, mentioned by Oliver (d); or from that incapacity of the blood to coagulate occasionally observed in peculiar constitutions, of which I have seen many instances, and which, unless properly treated, as surely, though sometimes more slowly destroy the patient, as if an artery had been wounded and left undivided or untied. The treatment recommended for these cases is very various, and must necessarily vary according to their cause and* situation. In the more trivial cases the applica- tion of rag repeatedly dipped in cold water, so as to reduce the vascular action of the part is often sufficient, either with or without pressure, which is advantageous when it can be made efficiently, as on the head and chest, and also, though less ad- vantageously, on the limbs ; but upon the belly pressure is of little avail, as from the yieldingness of the parts, it cannot be continuous. If a vessel, as for instance, the temporal artery, be wounded, it is best at once treated by division between the wound and the heart, as practised in arteriotomy. This plan will succeed if done early; but it will not always answer, if put off till the formation of spurious aneu- rysm, as in Green's case. Or the vessel may be found and tied. Or it may be compressed firmly between the bone and a piece of cork bound tightly on, either with or without division of the artery, as in common cases of the wound of such vessel. If the leech-bite be on a yielding part, Lowenhardt's (e) method of draw- ing the edges of the wound together with a fine needle and thread may be employed. But I prefer thrusting a couple of needles at right angles to each other, at a little dis- tance from the aperture below the bottom of the wound, and out at the opposite side; around which, including the whole bite, a strong thread is to be carried once or twice and tied tightly. After two or three days the thread and pins may be removed, and the bleeding has generally been stopped. Oliver has recommended, from his own experience, the application of plaster of Paris (/), and particularly mentions a case which was cured by this treatment, in which a pint of arterial blood was lost from the temple (g), and perhaps the temporal artery was wounded. Ridalfo (h) of Leghorn recommends the application of a cupping glass, which done, he says, a coagulum forms immediately, and he advises that the glass should be left on for a few minutes. On the other hand, Sir J. Murray (i) advises the employment of condensed air in a syringe ; but it is rather difficult to make out whether he has had practical experience on this point. The introduction of nitrate of silver, scraped to a very fine point, into the bottom of the leech-bite, is, so far as my experience goes, not so successful as related of twenty-two cases, infants and adults (j'), after the plan recommended by Donovan (k). In slighter cases a saturated solution of (a) Gazette des H6pitaux, vol. vii. p. 36. (h) Ripertorio di Medic, e di Chirurg. di 1833. Troino; quoted in Lancet, 1828-9, vol. i. p. (6) Revue Medicale. 1897, vol. iv. p. 149. 232. (c) Lancet, 1829-30, vol. ii. p. 394. (t) On the local and general Influence on (d) Ibid, 1834-5, vol. i. p. 304. the Body of increased and diminished At- (e) Above cited; quoted in Lancet, 1828-9, mospheric Pressure; in Lancet, 1834-5, vol. vol. ii. p. 400. i. p. 916. (/) Lancet, 1833-4, vol. ii. p. 209. (j) Lancet, 1829-30, vol. ii. p. 927. Ig) Ibid., 1831-5, vol. i. p. 304. (it) Annals of Pharmacy. OF SCARIFICATION.—OF CUPPING. 615 German tinder may be successfully used. Howison (a) says, that a thick layer of flour dusted on flannel is very rapid and efficacious in stanching bleeding leech-bites. One or other of these plans are almost invariably used and succeed, except when the blood cannot coagulate, and which is indicated by the failure of these means, and not unfrequently by the history of the case; under such circumstances it i3 necessary to use the actual cautery, or to express it more simply, a piece of thin iron wife heated red-hot and thrust down to the bottom of the wound ; and this treatment is almost universally successful, for it seems that the actual fire has some-peculiar effect upon the wounded vessels more than other escharotics have. I cannot explain in what this consists, but from repeated observation, I know that a red-hot iron wire will stop bleeding, when all other means have entirely failed. The introduction of small bits of hard-rolled sponge I entirely disapprove of, on this, as well as on most other occasions.—j. f. s.] 2629. If considerable ecchymosis, inflammation and suppuration should occur, the parts must be bathed with lead wash, or lead ointment should be applied. D.—OF SCARIFICATION. (Scarificaiio, Lat.; Scarificiren, Germ.; Scarification, Fr.) 2630. Scarification consists of more or less deep cuts with a lancet or bistoury, in any one part, whereby it is emptied of the fluid it contains. It is more frequently employed in inflammation of those parts- where leeches cannot well be applied, as for instance, inflammation of the tongue, of the gums, of the tonsils and the like. In considerable inflam- matory swelling of such parts as are surrounded with unyielding aponeu- roses or very thick cellular tissue, scarification, besides the local bleeding, produces also a lessening of the tension. It is also employed after the bites of rabid animals, under certain circumstances in gangrene, and in callous ulcers. Scarifications of the dropsical swelling of a part must be made quite superficially, and never then if there be accompanying ery- sipelatous inflammation, or a great degree of exhaustion, because gan- grene generally follows. E.—OF CUPPING. (Applicatio cucurbitarum cum incisione, Lat.; Schropfen, Germ.; Ventouses, Fr.) 2631. Cupping differs from scarification, in that before the skin is cut into at any one part and in different directions, with the scarificator, or a bistoury, congestion of blood is promoted in it, by the application of a cupping glass; and afterwards a suitable quantity of blood may be drawn. 2632. When the part to be cupped has been rubbed with a sponge dipped in warm water, a cupping glass is held over a burning lamp to properly expand the contained air, and then as quickly as possible, and cleverly applied to the spot chosen. After a few minutes, when the skin has been properly drawn up into the cupping glass, the glass must be removed, whilst the forefinger is slipped under its edge. Upon this part the scarificator is now placed, after having set the lancets and drawn up the spring, and then pressing upon it, the lancets wound the skin. A (a) Medical Gazette, vol. vi. p. 207. 1830. 616 OF CUPPING. lancet or bistoury may be used instead of the scarificator, with which more or less deep cuts are made upon the part chosen. For the purpose of discharging the blood, a cupping glass is to be again applied in the way already mentioned ; and when nearly full, it must be removed, the part cleansed and the glass put on again. The cut may be repeated in any direction with the scarificator. When no more blood flows, the part must be cleaned and covered with a firm compress. Dry cupping consists simply in the application of cupping glasses without scari- fication, and is for the purpose of drawing the blood to any one part. [As occasionally scarificators and cupping glasses are not at hand, the following substitutes, which I recollect having heard a friend in the military service mention, may be employed. Some short incisions near each other are to be made through the skin, and over them is to be whelmed a tumbler, wineglass or teacup, the air in which is to be exhausted or rarified by burning within a piece of paper. Instead of a scarificator, Dr. Osborne (a) proposes his poly tome, which consists of several lancets with circular edges fixed parallel in a frame, with a handle. It is drawn quickly along the skin, so as to make incisions an inch in length, and one- sixteenth or one-eighth of an inch deep. He supposes a better flow of blood will be procured by this instrument than by the scarificator. Cupping is sometimes attended with danger and even loss of life, either from wounding an artery, or from inability of the blood to coagulate. Of the latter kind it has been several times noticed, when cupping has been employed during an attack of jaundice, that very tiresome and dangerous haemorrhage ensued from the want of coagulability of the blood. In one case which came under my care a few years since, all kinds of styptics and escharotics were used in vain, at last I employed the actual cautery, which stopped the bleeding, and the patient did well. In another case, in which a girl had been taking for some time nitrate of silver on account of epilepsy, and for some cause or other she was cupped on the loins, continued haemorrhage from the wounds ensued, which nothing could stop, not even the actual cautery, and the patient bled to death.—j. f. s.] 2633. In regard to the preference of leeches, or cupping for local blood-letting, it may be observed, that in general the former are more convenient as they can be applied on every part, and their effect is not attended with so much irritation as from cupping. But the latter circum- stance gives an undeniable preference to cupping over leeching in many cases of chronic, deep-seated, especially rheumatic or arthritic inflamma- tion, as not merely is the bloodletting, but also powerful derivation to the skin effected, as for example in sciatica, lumbago, and many affections of the joints and the like (1). Sarlandiere's (£Q bdellometre corresponds to cupping. For the purpose of effecting a powerful derivation of blood, without an actual bloodletting, Junod (c) has invented an apparatus consisting of a glass cylinder to enclose the whole limb, around which it closely and air-tightly fits at the upper end. At the lower end is a cock, connected with an elastic tube and an air-pump, by means of which the air is drawn out of the cylinder. As this is done, the skin expands and reddens, the size of the limb is increased, the temperature raised, and transpiration becomes so profuse, that it collects- on the walls of the cylinder. At the same time the head becomes light, the countenance pales, the pulse in the tem- poral artery slow, thready and faint; swooning ensues and sometimes nausea. By this apparatus, severe pressure with air can also be effected ; by which the limb is rendered pale, the superficial veins are emptied, the bulk of the part diminished, and the circulation interrupted. After the operation the limb remains considerably (a) Observations on Local Bloodletting; in (c) Bourgery, Traite complet de l'Anato- Dublin Journal of Medical Science, vol. iii. mie de l'Homme, comprenant la Medecine p. 334. 1833. Op(5ratoire, vol. vi. pi. 83.—Froriep's Chi- (6) Bdellometre. Paris, 1818. 8vo. rurg. Kupfertaf., cccxcvii. OF PUTTING IN ISSUES. 617 lighter, and moves more securely and easily. Moreover, especially when it has been used upon one of the lower limbs, dizziness, rushing in the ears, seeing sparks, disposition to apoplexy, and difficult respiration have been produced. [I cannot agree with Chelius in his preference of leeches over cupping, as causing less irritation, for I have witnessed the contrary again and again. The leech-bites, specially in persons with irritable skin, often fester, and I have occasionally seen tedious sores, and difficult to be healed resulting from them. They also not uncom- monly are attacked with erysipelatous inflammation, which, though generally yield- ing to a bread poultice, sometimes assumes a serious character. The danger ensuing from their occasional disposition to bleed indefinitely has been already mentioned (par. 2028.) And even under the most favourable circumstances, the quantity of blood obtained by them is very uncertain, and the exhaustion of the patient by exposure, and mopping the parts with a sponge, it may be for hours together, render their employment far from desirable, excepting on parts where cupping cannot be performed on account of disfigurement as on the face, or where the parts are too yielding, so that a cupping glass would be almost filled by them, as on the belly, or where important vessels and nerves are in the immediate neighbourhood, as in the neck and the like, or where there is merely a small inflamed lump, upon which a cupping glass cannot be conveniently applied. With these exceptions cupping is infinitely preferable to leeches, and more especially as a determinate quantity of blood can be obtained with little additional pain for a short time, the whole operation being generally completed in half an hour or less without fatigue to the patient. So far as I have noticed, the after-irritation of cupping is very far less frequent than that from leeching, and therefore from all these circumstances I should always recom- mend cupping rather than leeches, where it can be employed.—j. f. s.] II.—OF PUTTING IN ISSUES. (Fonticulus, Lat.; Fontanelle, Germ.; Fonticule, Fr.) 2634. By the term Issue is meant an artificially produced, and conti- nually suppurating wound, which is made either with the knife, with blister plaster, with the actual cautery, or with caustic. The latter two will be specially considered afterwards. The place for the issue is determined by that of the disease which calls for it, though generally a part is chosen where much cellular tissue is beneath the skin, usually between two muscles, on the arm between the m. biceps and the m. deltoides, omthe thigh between the m. vastus internus and m. gracilis, on the calf between the m. gastrocnemius and m. soleus, on the breast between two ribs and so on. Large vessels and nerves must be avoided. 2635. When using a bistoury, a small fold of skin must be nipped up and cut through lengthways, and the wound stuffed with a little wad of lint, and covered with sticking plaster. On the second or third day the dressing should be taken off, the wound cleaned, and one or more peas put into it (I). A square piece of sticking plaster and a compress are put on and fastened with a bandage. The issue must be dressed daily, once or twice, according to the degree of suppuration, and always pro- perly cleansed. [(I) The best and cleanest materials for issues are little, solid, glass beads, which soon imbed themselves, and not swelling like peas, excite little irritation, and may be worn for months, merely taking them out for washing every day, and returning them to their bed.—j. f. s.] 2636. If on account of the patient's dread of the knife, a blister be em- ployed, a round piece about half an inch in diameter, must be applied 618 OF INTRODUCING A SETON. and kept on till vesication take place, when it is to be taken off and the cuticle removed. One pea is then to be put upon the exposed part, fixed with sticking plaster and pressed with a bandage, so that the pea may sink into the skin. The after-treatment is the same as in the former case. 2637. If the issue cause violent pain, the pea must be removed, or if there be several, their number must be diminished ; this must also be done if there be much inflammation, and lead wash applied over. If there be not proper suppuration, the pea must be smeared with digestive salve, the issue touched with lunar caustic and the like. If the suppura- tion be too great, the pea must be removed. If fungous flesh grow up around the issue, it must be got rid of by touching with caustic or cut off with scissors. If the part waste in which the issue is, it must be moved elsewhere. The issue must not be allowed to heal too quickly. The method of proceeding employed under the name of the English Issue, is, in its application, very agreeable to the patient. Ill—OF INTRODUCING A SETON. (Setaceum, Lat.; Eiterband, Haarseil, Germ.; Seton, Fr.) 2638. The Seton consists of a strip of linen unravelled at each edge, or of a strand of several cotton, silk or hempen threads, which are drawn into the skin or into any tumour, to keep up a continual discharge, and a certain degree of inflammation, for the purpose of diminishing any tumour by continued suppuration, and to keep up the passage through any canal. The introduction of a seton L> managed in different ways. 2639. If the seton be passed through the skin, a fold of skin must be lifted up vertically in the neck, with the finger and thumb of the left hand, and pierced at its base with the seton-needle, in the eye of which is the strand of threads or strip of linen, and as the needle is drawn out, these follow it. If there be not any seton-needle at hand, the raised fold of skin must be pierced with a double-edged bistoury, and an eyed probe armed with the seton-threads carried through the opening thus made. Both openings are to be covered with a wad of lint, which is fastened with sticking plaster, and the loose ends of the seton put into a compress, and retained with a proper bandage. [Of late an Indian rubber tape, about three-eighths of an inch wide, and a line thick, has been used instead of threads or linen, for a seton. It is much belter than either of the latter, as it does not get loaded with matter and become offensive. It is easily passed, after thrusting a double-edged bistoury through the skin, through the opening thus made.—j. f. s.] 2640. Passing a seton into a cavity containing fluid, for instance, an abscess, is to be managed as already directed (par. 57); or a somewhat curved silver canula is used, with a stilette, of which the front end has a trocar point, and its hinder end an eye, through which the strand of threads is threaded. The swelling is to be pressed, so that it maybe made sufficiently prominent, and the canula well oiled, with its point projecting, must be thrust through its lower part into the cavity of the swelling, then the point of the stilette drawn back, and the end of the OF THE APPLICATION OF BLISTER-PLASTER. 619 tube carried to the upper part of the cavity pressed against the skin, and then the stilette thrust through. The tube is now drawn out at the lower, the stilette at the upper wound and the threads introduced into the cavity. 2641. If the seton be passed into a swelling which does not contain fluid, either a seton-needle or a stilette with a trocar point and an eye must be used and carried in such direction, and so deeply through the mass of the tumour as not to run any risk of danger from wounding any considerable vessel or nerve. 2642. After the seton has been introduced it may be left alone for some days till suppuration be set up in its track; then, after removing the dressings and washing off the crusts at the wounds with lukewarm water, a fresh portion of the seton may be drawn through, the part already used cut off some distance from the wound, and the dressing renewed. In this way the seton is to be managed daily, once or twice a day, according to the degree of suppuration and the object purposed. If requisite, other remedies may be smeared upon the seton strand, and with it drawn into the canal of the wound; and when the strand has been used up, a new one may be attached to and drawn through with it. If the seton strand require thickening, more threads are to be added to it; if it need thinning, some must be taken from it; the strand or linen band must be gradually thinned, and when it is drawn out, moderate pressure applied. If there be bleeding in passing the seton-needle, it must be stopped with cold water or pressure. Severe inflammation requires the seton to be smeared with fresh oil, or simple cerate and soothing applica- tions. If the suppuration be profuse, strengthening remedies are to be employed, both externally and internally. IV.—OF THE APPLICATION OF BLISTER-PLASTER AND MEZEREON BARK. (Vesicatio, Lat.; der Setzen der Blasen-pfiaster, und der Seidelbastrinde, Germ.; le Visicatoire, et le Garou, Fr.) 2643. The effect of Blister-plaster is more or less severe irritation of a part kept up for a longer or shorter time. For this purpose Spanish- Fly Plaster (Emplastrum Cantharidis) is used, spread on linen or leather, applied to the part required, and bound on with strips of sticking plaster, a compress, and bandage, but not too tightly, or severe pain will be pro- duced, and the formation of a blister prevented. The time a blister should remain on varies according to the object of its application, the constitution and age of the patient. [The most cleanly, and as efficient a way of producing a blister, as with a plaster, is the use of a fold or two of lint, sopped in acelum cantharidis, and applied to the part with a camel's-hair brush to the extent required. Recamier and Trousseau have, for the same purpose, applied lint dipped in a strong solution of ammonia. When it is considered necessary to produce blistering as quickly as possible, other remedies have been resorted to, which are in fact only purposely-made burns and scalds, and will require at least some little caution in their use. Pigeaux (a) ap- plies a piece of lint, cloth, or paper, of the necessary size, just previously dipped in spirits of wine, and passing a match rapidly over it, at once sets it a light, it is extinguished, and then the skin may be removed, leaving the cutis perfectly dry and (a) Bulletin de Therapeutique, vol. ii. p. 176* 620 OF THE APPLICATION OF MEZEREON BARK. unharmed. (On the contrary, I should think the dryness were a tolerable proof that a slough had been produced.—j. f. s.] Boiling water has also been poured in a thin saucer upon the part to be blistered, or by soaking a sponge, and applying it for a few minutes, but not long enough to destroy the cutis. Sir Anthony Carlisle recommended the application of a spatula dipped in boiling water; in other words, a gentle burn. Blisters are often left, as to their mode of application and the length of time they are to be kept on, entirely to the will and pleasure of an ignorant nurse, and the patient consequently suffers much more pain than necessary, and sometimes, also, has sloughing of the cutis, which, if the patient be a female, and the blistered part be the neck or any other visible part, will get the medical attendant into much trouble, which he deserves; though occasionally, even with the greatest care, this tiresome accident will occur when the skin is irritable. In applying a blister, one of the greatest inconveniences arises from some of the little pieces of fly sticking to the skin, or even to the cutis, if the skin break whilst the blister is applying; this much increases the pain and irritation, and can be very easily avoided,"by merely laying a piece of tissue paper or any other thin paper be- tween the plaster and the skin, and if the plaster be bound firmly on, it will operate as readily through the paper as if it were in immediate contact with the skin. A blister is often directed to be kept on twelve or twenty-four hours, which at least is a great absurdity, and may be very inconvenient to the patient. It is only necessary to keep it on till the whole of the skin beneath it has fairly separated from the cutis and the serum has begun to be poured out, which in most persons will take place in six or eight hours. But with children even this will not do; the blister should be removed as soon as it has caused bright redness of the skin, which gene- rally happens in two or three hours; it should then be removed and left alone for a little while, as the blister very soon after rises, if it have not already. The younger the child is, the more necessary it is to attend to this point, or sloughing will ensue, and death has been known to follow in consequence. Indeed with children, I am by no means sure that, in most cases, a mustard poul- tice is not preferable te the application of a blister. It should be made with mustard and warm water, (some recommend vinegar,) rather thinner than if for the table, as if made stiff it is much less active. It should then be spread about a quarter of an inch thick on fine muslin, and another layer of muslin being put upon it, applied to the part, and kept on ten, fifteen, or twenty minutes, according to the redness and pain. In some persons it will even blister. When removed, the skin should be carefully sponged clean with warm water, otherwise the irritation, which is very great, will continue. In the few persons whose skin is blistered with difficulty, it is best to apply pre- viously a mustard poultice till the skin becomes reddened and painful.—j. f. s.j 2644. When the blister has risen, the plaster must be carefully re- moved, the blister opened with scissors, the water emptied, and the part dressed with simple cerate, fresh butter, or any other mild ointment. If requisite to keep up the suppuration for a time, it must be dressed with ung. resine, or some digestive.ointment to which cantharides has been added, or with ung. sabine, which is best of all. [I must confess I am no advocate for open blisters, the only special result of which appears to me that of putting the patient to unnecessary pain. All that is desirable, to wit, derivation,,is much more effectually done by a succession of small blisters, about the size of a half-crown piece, around the part affected, which may be repeated ad infinitum, with scarcely any inconvenience to the patient. They are called flying blisters.—j. f. s.] 2645. When a blister is applied to a part not very sensitive, its opera- tion may be promoted by rubbing it with a hot flannel or with vinegar. If the inflammation be very violent, it must be soothed with some softening and cooling remedy. If the cantharides be absorbed, it will produce strangury, for the relief of which, mucilaginous drinks and emul- sions with camphor, may be given. Swellings of the neighbouring glands, OF VACCINATION. 621 which sometimes arise, may be relieved by the application of soothing ointments and poultices, and by the removal of all irritation. 2646. For the employment of Mezereon bark {Seidelbast, Germ.) a piece of the bark an inch and a half long, and the same wide, should be soaked eight or ten hours in vinegar or water, after which, it is to be applied with its smooth surface next to the skin, generally upon the arm, at the insertion of the m. deltoides, and covered with a piece of oiled silk compress, and roller, to keep it close. After ten or twelve hours, when the bandage, is removed, if» the skin be sufficiently inflamed, a piece of oiled silk is to be applied on the inflamed part and fastened with com- press and bandage ; but if the first application have not been effective, a second piece of the bark must be applied. About the second or third day a new piece of bark is put on, the skin rises, and a serous fluid exudes. The part must be cleansed daily with warm water or milk; and if the inflammation be very great, it must be rubbed with warm milk and bound up with some mild ointment. The pustules around the irri- tated part in general yield to cleanliness and repeated washing with warm water. [2646.* Another very excellent and very gentle mode of blistering is with croton oil, ten or a dozon drops of which should be gently rubbed over the surface with the finger, protected in a piece of oiled silk, for two or three following nights. Usually a slight stinging is felt accom- panied with puffiness of the part on the second or third day, and this is followed by a crop of small vesicles, which speedily maturate, in a day or two after dry up, and fresh cuticle is formed. It is one of the best modes of blistering, if not required to be speedy.—j. f. s.] V._OF VACCINATION, OR INOCULATIOxN WITH COW-POCK. (Vaccinatio, Lat.; Einimpfung der Kuhpocken, Germ.; Vaccination, Fr.) Jenner, Eoward, M.D., An Inquiry into the Causes and Effects of the Variolas Vaccinae, a Disease discovered iii some of the Western Counties of England, par- ticularly Gloucestershire, and known by the name of Cow-pox. London, 1798. 4to. Ibid., Further Observations on the Variola? Vaccinas, or Cow-pox. London, 1799. '4to. Ibid., A Continuation of Facts and Observations relative to the Variolae Vaccinae, or Cow-pox. London, 1800. 4to. Bryce, James, Practical Observations on the Inoculation of Cow-pox, pointing out a new Mode of obtaining and preserving the Infection, &c. Edinburgh, 1809. 8vo. Woodville, William, M.D., Reports on a Series of Inoculations for the Variolae Vaccina?; with Remarks, &c. London, 1799. 8vo. Creaser, Thomas, M.D., Evidences of the Utility of Vaccine Inoculation. Bath, 1801. Gregory, George, M.D., Lectures on the Eruptive Fevers. London, 1843. 8vo. [Coxe, J. R., Practical Observations on Vaccination. Philadelphia, 1802. 8vo. Fisher, J. D., On Small-pox, Varioloid Disease, Cow-pox, &c. Boston, 1829. 4to.—g. w. n.] 2647. Vaccination consists in the insertion of cow-pox matter under Vol. hi.—53 622 OF VACCINATION. the skin, whereby a peculiar diseased process is set up, which destroys or diminishes the susceptibility to the contagion of small-pox. The vac- cination is performed either with fresh cow-pox matter, conveyed from one individual to another, or with dry matter which has been previously moistened. Othermodes of vaccination are inadmissible, and the former is the best, as it is also at present the most common. Cow-pox matter comes originally from the pustules on the teats of cows in vari- ous countries (1). The matter to be used, must be obtained from an uninjured pellucid pustule, between the sixth and ninth day, and be clear and transparent. If dry matter be used, it should have heen taken under the just-mentioned circum- stances, and should have been kept safe against the effect of both light and air. To effect this, various modes have been advised, as placing between glass plates her- metically sealed, on threads of lint or cotton, on golden or bone needles, in glass tubes, and so on (2). [(1) "The earliest notice I have ever seen," says Gregory, " of cow-pox, is to be found in a weekly paper published at Gottingen, in 1769, where we learn that such a complaint was not uncommon in the neighbourhood of that town, and that those who caught it from the cows flattered themselves they were secure from the infection of small-pox. A notion of the same kind had long prevailed in Glou- cestershire, a great dairy country, and had often been forced on the attention of the provincial surgeons. But no one thought seriously of this rural tradition, or dreamt of applying it to the general benefit of mankind, until Jenner arose, (p. 184.) It was not until the year 1?96 that Jenner began to experiment with cow-pox, although he had been talking and inquiring about it for at least thirty year6. The decisive ex- periment was made on the 17th May, 1796, on a boy, eight years of age. He was tested with small-pox on the 1st July of that year and found to be unsusceptible." (p. 187.) In June, 1798, Jenner published his paper, An Inquiry into the Causes and Effects of the Variolae Vaccinae, $rc.; and " it redounds to the honour of St. Thomas's Hospital," says Gregory, " that its officers were the first persons in England, to put Jenner's discovery to the test. Mr. Cline vaccinated a boy here in the last week of July, 1798, with dried lymph, which had been kept three months in a quill. The boy had diseased hip, and Mr. Cline proposing to con- vert the vaccine pock into a pea issue, inserted the matter on the outside of the hip. Dr. Lister, formerly physician of the Small-Pox Hospital, (and also of St. Tho- mas's,) watched the progress of the case. The boy was inoculated, almost imme- diately afterwards, with small-pox in three places, but the slight inflammation that arose subsided on the fourth day. The experiment, therefore, was perfectly suc- cessful." (p. 187.) (2) According to Gregory, " vaccine virus may be preserved fluid and effective for two or three days in small bottles with projecting ground stoppers, fitted to re- tain the matter. It may be preserved for a like time in small capillary tubes, having a central bulb. This is the mode used in France for the transmission of vaccine lymph to the provinces, and which proves very effectual ; but if you at- tempt in this manner to transmit lymph to the East or West Indies, you will fail utterly. Ivory points, when well armed and carefully dried, are very effective. They will retain their activity in this climate for many months, and they are found to be the most certain mode of sending lymph to our colonies. Some practitioners prefer glasses to points, but they are less certain. The employment of scabs for the propagation of cow-pox was lirst recommended by Mr. Bryce, of Edinburgh, in 1802. It is a very excellent mode of transmitting vaccine matter to distant coun- tries, but some nicety is required in operating with scabs, which experience alone can teach." (pp. 198, 99.) As regards the period at which lymph should be taken for vaccination, Gregory says :—"The younger the lymph is, the greater is its intensity. The lymph of a fifth-day vesicle, when it can be obtained, never fails. It is, however, equally powerful up to the eighth day, at which time it is also most abundant. After the formation of areola, the true specific matter of cow-pox becomes mixed with vari- able proportions of serum, the result of common inflammation, and diluted lymph is always less efficacious than the concentrated virus. After the tenth day the lymph becomes mucilaginous and scarcely fluid, in which state it is not at all to be OF VACCINATION. 623 depended on. * * * Infantile lymph is more to be depended on than the lymph obtained from adults. The matter of primary vaccinations is more energetic than that of secondary vaccinations." (pp. 195,96.)] 2648. Vaccination is a completely dangerless operation, which may be performed at any time of year and in any age. It seems, however, most suitable, unless there be prevailing small-pox, to perform it in the second half of the child's first year, in spring, summer, or autumn, when the child's health is undisturbed. 2649. If vaccination be performed from a fresh pustule, the child must be placed on the lap of a sitting person. The point of a lancet is to be introduced into such pustule, as above described, of a person near at hand, so as to bring away some of the clear matter upon it without drawing blood. The child's upper-arm is then grasped, the skin drawn tight, and the charged lancet thrust in obliquely, about a line beneath the epidermis, which must be gently lifted, the point of the lancet moved a little backwards and forwards, and the left thumb being placed on its point, the lancet is then laid flat, and drawn out. In this way, three insertions of matter are to be made on each arm. Dressing is unneces- sary. If the wound bleed, it must be left to dry, and not be wiped off. [For the proper performance of vaccination, Gregory says :—" Let the lancet be exceedingly sharp. It should penetrate the corion to a considerable depth. The notion that the subsequent effusion of blood will wash out the virus, and thus de- feat our intention, is quite imaginary and groundless. Provided that a genuine lymph of due intensity has once come in contact with the absorbing surface of the cutis vera, the rest is immaterial. The vessels of the part have received the specific stimulus, and nothing can prevent the advance of the disorder, but some constitu- tional cause. In making the incision, the skin should be held perfectly tense be- tween the forefinger and thumb of the left hand. The lancet should be held in a slanting position, and the incision made from above downwards, * * * I would recommend that, with lymph of ordinary intensity, five vesicles should be raised, and that these should be at such distances from each other as not to become con- fluent in their advance to maturation." (pp. 197, 98.)] 2650. If vaccination be performed with dry matter, it must be moist- ened with pure water, so that a part of it may be got upon the lancet- point. In other respects, the proceeding is precisely the same as in the former mode. 2651. The appearances which ensue after vaccination, if it be ef- fectual, are the following:— On the first and second day only a trace of the slight stab is observed. On the third day a blush appears at the place of vaccination, which becomes more distinct on the fourth and fifth days, and in its middle a little hard knob rises, which increases and is surrounded with a reddish areola. On the sixth day the colour of the knob becomes reddish white, it contains some fluid, presents a pit in its centre, surrounded with a swollen edge; the hardness is felt as deep beneath the skin as it is ele- vated above it; the red areola becomes more considerable. On the seventh day the vesicle distinctly contains a transparent fluid, and the other appearances are more decided. On the eighth day the vesicle has attained the size of a lentil; it is still most commonly filled with clear fluid, and surrounded with a more or less extensive areola. On the ninth day this areola is larger. On the tenth day the vesicle has become a pustule, in which the contained fluid becomes untransparent, thick, and converted into pus, and the pit in its 624 OF VACCINATION. middle disappears. On the eleventh and twelfth day the red areola diminishes, the pustule begins to dry, is converted into a dusky-brown, blackish, thick and tough scab, which falls off about the four-and-twen- tieth day, leaving a flat scar (1). With these local symptoms, there occur, on the seventh, or more commonly on the eighth day, a slight attack of fever, in which, howrever, but few children lose their appetite and their usual liveliness. At this period, if the areola be very much inflamed, there is often pain and swelling of the axillary glands (2). [(1) To the above account may be added from Gregory, that; "by aid of the microscope, the efflorescence surrounding the inflamed point will be distinctly per- ceived, even on the second day. On the fifth day the cuticle is elevated into a pearl- coloured vesicle, containing a thin and perfectly transparent fluid in minute quantity. The shape of the vesicle is circular or oval according to the mode of making the incision. On the eighth day the vesicle is in its greatest perfection, its margin is tinged and sensibly elevated above the surrounding skin. In colour the vesicle may be yellowish or pearly. The quantity of fluid which it contains will be found to vary much. When closely examined, the vesicle will exhibit a cellulated struc- ture. The cells are eight or ten in number, by the flow of which the specific matter is secreted. The vesicle possesses the umbilicated form belonging to variola. * * * On the eleventh day the areola begins to fade, leaving in its decline, two or three concentric circles of a bluish tinge. Its contents now become opaque, the vesicle itself begins to dry up, and a scab forms, of a circular shape, and a brown or mahogany colour. By degrees, this hardens, and blackens, and at length between the eighteenth and twenty-first day, drops off, leaving behind it a cicatrix of a form and size proportioned to the prior inflammation. A perfect vaccine scar should be of small size, circular, and marked with radiations and indentations. These show the character of the primary inflammation, and attest that it had not proceeded beyond the desirable degree of intensity. Many of the most perfect scars disappear entirely as life advances, (pp. 189, 190.) (£) " Until the eighth day," continues Gregory, " the constitution seldom sympathize^. At that period, however, it is usual to find the infant somewhat rest- less and uneasy. The bowels are disordered. The skin is hot, and the night's rest is disturbed. These evidences of constitutional sympathy continue for two or three days. There is, however, much variety observable here. Some children suffer slightly in their general health throughout the whole course of vaccination. Others exhibit scarce any indication of fever, although the areola be extensive, and the formation of lymph abundant." (pp. 190, 91.)] 2652. The above named symptoms sometimes occur according to this order, only about two days later, but without interfering with the effect of the vaccination. But if the course of the vaccine vesicle be irregular, if it be formed on the first or second day, if it show no pit in its middle, if its contents be not clear and transparent, but yellow and purulent; further, if the inflammation spread more widely, if the hardness on the circum- ference of the pock be wanting; if the vaccination spot be from the verv first converted into an ulcer, or a mere slough; if instead of a dusky- brown or blackish scab, a yellowish-green, loose scab be formed ; if the febrile symptoms be entirely absent, or do not appear at the proper time, the vaccination must be considered as a failure, and the security from it of no value. The cause may rest on vaccinating with bad matter, if it be not clear, or if the lymph employed be putrid, if it be inserted too deeply, or if it be inserted with a blister-plaster. [On this point Gregory remarks :—" Occasionally we meet with persons who, from some peculiarity of habit, are wholly insensible to the vaccine poison, in what- ever intensity, and by whatever mode it is applied. They receive it as they would so much cold water. The proportion of mankind who exhibit this idiosyncrasy is very small. I may have seen thirty or forty such cases in the course of my life. It would be very interesting to determine whether this constitutional inaptitude to OF INFUSION AND TRANSFUSION. 625 cow-pox denotes a like inaptitude to receive and develope the variolous poison. In the few cases which I have seen, where inoculation was subsequently tried, the insusceptibility was proved to extend to both poisons; but I have read of instances of an opposite kind. * * * The insusceptibility to the vaccine poison is, in some cases, obviously dependent on constitutional weakness, displayed in the slowness of dentition, the imperfect ossification of the head, and the emaciated aspect of the body. There exists here an atony of the absorbent system." (pp. 188, 189.)] 2653. The after-treatment of vaccination simply requires proper regu- lation of the health. Care must be taken that the child do not touch or scratch the pock. In severe inflammation cold applications must be made ; and if much fever, proper diet must be directed. If there be much suppuration at the vaccination spot, lead wash must be applied. Eruptions of the skin, which sometimes occur after vaccination, eitheE subside of themselves under proper treatment, or by the use of slightly^ diaphoretic remedies (1). If the vaccination fail, it must after some time be repeated. If vaccination with the lancet fail repeatedly, it must be performed with a thread soaked in the cow-pox matter, after previously moistening it with warm water, and inserted into a slight cut in the upper-arm, over which a piece of linen spread with cerate, is to be placed, and fastened with, a bandage, because this mode of vaccina- tion is certainly successful. [(1) "It is not uncommon," says Gregory, "to find the child's body covered, generally or partially, with a papulous eruption, of a lichenous character, from the ninth to the twelfth day, or even later. It is seldom seen in adult vaccination; but is frequent in children full of blood, in whom numerous., vesicles had been raised, which discharged freely. Vaccine lichen, as this eruption is properly called, often-. occasions great anxiety in the mind of the parent, from a suspicion that small-pox is coming out. I have seen it in such intensity as to be followed by minute vesicles; but this latter appearance is. very rare. It is an accidental occurrence, chiefly at- tributable to the peculiar delicacy of the child's skin and fulness of habit. Like the constitutional irritative fever, it indicates that the disease has taken effect on the system; but it is not deemed essential to. the success of the process." (p. 191.)]. VI.—OF INFUSION AND TRANSFUSION. Denis, J., Lettre sur la Transfusion du Sang. Paris, 1667. Merklin, De Ortu et Occasu Tranfusionis Sanguinis. Nurimb., 1679. Major, Chirurgia Infusoria. Kilon., 1767. Ettmuller, De Chirurgia. Transfusoria.. Lipsiae, 1697. Hemmann, Geschichte der Infusion, und Versuch,, die sichere Anwendung dieser- Operation zurerweisen; in Med. Chirurg. Aufeatze, p. 122. Berlin, 1778. Scheel, Die Transfusion des Blutes und Einspritz.ung der Arzneien in die Adern, historisch und in Riichsicht auf die Heilkunde. Kopenhagen, 1802-1803. Hufeland, E., De Usu Transfusionis Sanguinis, praecipue in Asphyxia. Berol.,. 1815. Graefe, Dissert.de NovS. Infusionis.Methodo. Berol., 1817. he Boer, Dissert, de Transfusione Sanguinis. Groning., 1817. Percy et Laurent, Article Infusion ,• in Diet, des Sciences Medic, vol. lxxv. Blundell, James, M. D., Experiments on the Transfusion of Blood by the Syrino-e; ■ in Medic.-Chir. Trans., vol.. ix. p. 56, 1818. Ibid., Physiological and Pathological Researches. London, 1825. 8vo. Tietzel, Dissert, de Transfusione Sanguinis. Berol., 1824. Dieffenbach, J. F., Die Transfusion des Blutes und die Infusion des Arzneien in die Blutgefasse, vol. i. Berlin, 1828. Heyken, Dissert, de Transfusione et Infusione. Rostoch, 1830. Blasius, Klinisch-chirurgische Bemerkungen, p. 123. Halle, 1832. Marcinkowsky ; in Hamberger Zeitschrifte, vol. i. part.iii. 53* 626 OF INFUSION. Berg; in Wiirtemberger Correspondenzblatt. 1838, Jan. Giesler; in Holscher's Annalen, vol. ii. part ii. Berthold; in same, vol. iii. part iv. 2654. Infusion consists in opening a vein, through which opening the pipe of a syringe may be introduced upwards, some medicated fluid in- jected, and the wound of the vein afterwards treated in the same way as that made in bloodletting. This operation, which in the latter half of the seventeenth century attracted great attention, was especially employed in those cases where no medicine could be taken by the mouth. It has been sometimes used successfully when foreign bodies had stuck in the throat, (par. 1731,) as well also as in cases of seeming death. Infusion, mentioned by Magnus Pegelius and Libavius in 1615 ; and practised on a dog by a Captain G. von Wahrendorff in 1642; was first subjected by Ch. Wren, who first performed it on a malefactor, in 1656, to philosophical examina- tion. The English Physicians, Clark, Lower, and others, made experiments with it upon brutes; Major in 1664, and Elsholz in 1665, first employed it on men; Schmidt, Purmann, and P. Sarpi, especially occupied themselves with it. How- ever, it soon sank in the estimation of physicians, and has only of later years been employed in a few cases in Germany by Kohler, Hemran, Meckel, and others. After the early cases and his own experiments upon this subject had been collected by Scheel, the operation was performed in Germany by Graefe and Horn, and by Laurent and Percy in France, on men. Bichat, Nysten, Seiler, Magendie, Orfila, and Dieffenbach, instituted some exceedingly interesting, and for physi- ology, important experiments upon the injection of different kinds of matters into brutes, and have employed this operation on man, as for instance in tetanus and cholera. The most complete account of infusion and transfusion is given by Scheel and by Dieffenbach. The effect of the injection of any matter into the veins is different according to its nature and the nature of the disease. The usual effects which all injections produce, besides those peculiar to them, are, sweating, frequent vomiting, shuddering of the whole body, and sometimes fever. All the remedies to be injected must be dissolved in water and be only as warm as the blood. In stubborn nervous diseases epilepsy, affections of the mind, hysteria, tetanus and trismus, in dyscrasic diseases, syphilis, gout, obstinate diseases of the skin, in typhus and intermittent fevers, infusion has been tried, and very different remedies have been injected. Narcotic remedies, as belladonna, opium, hyoscyamus, digitalis nux vomica, stryehnine, stramonium have generally dared only to be given in two-thirds of their ordinary dose; salt is borne in large quantity; they have the same effect as if taken into the stomach, though their operation is mostly very irregular. Simple warm water, which Magendie has injected in hydrophobia to the amount of two pints, by which quietude though not cure has been effected, produces great faintness, violent sweating, and increased secretion of urine; sometimes when much is injected, watery stools; and if it be thrown in cold, severe shivering with dry cough, pale urine, faintness, and severe sweating. In tetanus Percy, Laurent and Onsenoort have found good results from injecting extr. opii and exlr. daturas slramonii. In cholera Latta injected a solution of salt, consisting of two to three drams of nitre and two scruples of carbonate of potash to six pints of distilled water, at a temperature of 112- Fahrenheit, to the amount of six or eight pints at once, and repeated it, so that from fifteen to forty-four pints were thrown in. In Germany this was tried by Zimmermann, Casper, Blasius and others, but it produced only a passing effect. In cases of foreign bodies in the throat, Kohler, Balk, Kraus and Graefe have employed with advantange an injection of a solution of two to six grains of tartarized antimony, in half an ounce to an ounce and a half of distilled water, with the result already mentioned (par. 1731); and Meckel has also used it in a ease of seeming death. 2655. For injection, a very small vein should not be chosen, the vena cephalica is best. After the arm has been properly fixed, a fold of skin is to be made over the vein, and cut through lenghways from an inch and a half to two inches in the course of the vein; the vein is to be separated OF TRANSFUSION. 627 from the cellular tissue and two threads carried round it; after which it is to be lifted a little up and opened lengthways with the lancet, to an extent corresponding with the size of the pipe. After having filled the pipe with warm water, it must be passed in towards the heart, the threads tied firmly around it so that the blood shall not escape, and then it is to be held by an assistant. The syrihge heated by dipping in warm water to the temperature of the blood is now filled with the fluid warmed to the same degree, and its point being directed upwards, some of the fluid is squirted out, so that all air may be got rid of; it is then intro- duced into the pipe, and the fluid slowly and at intervals injected into the vein. If more fluid have to be thrown in, the syringe must be removed, the opening of the pipe covered with the finger, and the injec- tion repeated as before. When the injection has been completed, the threads are to be removed, the pipe carefully withdrawn from the vein, and the wound compressed with the thumb and finger of the left hand. The wound in the skin is to be brought together with slips of sticking plaster, over which a little compress and a bandage are to be applied, as after bloodletting. To prevent inflammation cold applications are to be made for some days. The practice of opening the vein after putting on a bandage, as in bloodletting, and injecting after the removal of the bandage is improper, as the injection may go into the cellular tissue. According to Blasius, the vein should be laid bare by a cut upon the skin, compressed at the upper part of the wound, opened in its longitudi- nal axis with a lancet, and into this aperture the little tube immediately inserted. For the injection he employs a tube with a pig's bladder; Scheel uses a syringe with an elastic tube ; others an Indian rubber bottle, Helper's funnel of transparent horn ; Hager uses a glass blowpipe with a silver syringe; Graefe opened the vein with a thin curved trocar which he thrust into the swollen vein, drew out the stilette, allowed an ounce of blood to eseape from the canula, and into it introduced a closely- fitting syringe, with which he injected the fluid. 2656. Transfusion consists in opening a vein, into which blood is con- veyed from the artery or vein of another person, {immediate transfusion,) or by means of a syringe (mediate tranfusion, infusory transfusion.) The history of this operation is connected with that of infusion. The notion of improving the juices, and of curing cachectic and dyscrasic diseases by the transfusion of the blood of man or brutes, which was very preva- % lent in the latter half of the seventeenth century, has not been confirmed by experience. The operation was nearly forgotten, and only in modern times has been brought into use successfully in cases of loss of blood, especially after childbirth, and also in continued and irremediable vomit- ing, where death from inanition was dreaded (Blundell). Only in such cases can its employment be advantageous, as even in cholera, its use has been without any beneficial result. Although M. Pegelius and Paola Salvi are named as the discoverers of transfu- sion, Libavius, and afterwards Colle, noticed it, yet it was first performed in France by Denis and Emmerez in 1667, and by King afterwards in England on man; in Germany by Kauffmann and Purmann. Notwithstanding the predilection of many practitioners for this operation, its results were not such as to keep it in sight. Rosa first repeated it in 1783; Scheel in 1802 collected the experiments already made in recent times. Blundell has successfully performed this operation in cases of loss of blood, and proposed it in vomiting which could not be stopped, and the inanition to be feared therefrom. Hence are the English practitioners decided on its employ- ment, and it has consequently been practised by Doubleday, Uwins, Waller, Knox, and others. Prevost and Dumas, as well as Dieffenbach, have made experiment*' 628 OF TRANSFUSION. interesting in a physiological view, and the latter has employed it, though without advantage, in cholera. Graefe has modified the apparatus for immediate transfusion. 2657. Although immediate tranfusion has the important advantage, that the blood not being changed by the influence of the air, its natural warmth is preserved, that it does not coagulate, and is even propelled by the action of the heart? yet, however, in recent times, mediate transfusion has been preferred, because, in immediate transfusion by tubes, the blood alwrays clots in a few seconds, whereby its passage is prevented, and generally, it is not known what quantity of blood has passed ; because, further, the passage of blood from one vein to another is impossible, as the stream of venous blood has not sufficient power, the opening of a small artery is insufficient, that of a larger one not admissible in men, venous blood is, generally, more proper, and human blood more suitable than that of beasts. Various apparatus have been proposed for immediate transfusion. Denis used two small silver tubes, curved at one end, and furnished with a shoulder, and at the opposite end, received into each other; he introduced the shouldered end of a tube into the artery of a beast, and that of the other }nto the patient's vein, and then con- nected both by inserting their free ends. Boehm connected them with a small piece of intestine, as for instance, that of a fowl, by stroking which, the passage of the blood might be encouraged. Instead of intestine, Regner de Graaf connected the two tubes with a piece of artery dissected from a beast, to which there was a side branch, partly to allow the escape of the air, and partly to note the constant stream of the outflowing blood, von Graefe's apparatus consists of a glass cylinder filled with warm water at a temperature of 29° Reaum., (97° Fahr.,) and furnished with a cock for the escape and renewal of the water, and through which a glass tube passed for carrying the blood, which received at one end another tube, of which that for the artery was curved and shouldered, and that for the other, elastic. In the performance of immediate transfusion, the beast, properly bound, is placed on a table near the patient, one of whose veins is opened, and a tube passed into it towards the heart; this is given to an assistant, and below the wound a compressing bandage is applied. The carotid or crural artery, according to the size of the beast, is then laid bare, a ligature passed around, and a director pressed upon it, and beneath the pressed part the vessel is opened lengthways with a lancet. Into this opening the end of one tube is inserted, arid the artery fastened around it with a ligature; the other end is inserted into the tube ensheathed in the vein, after the pressure has been removed from the artery, and a little blood allowed to escape. When the operation is finished the apparatus is withdrawn, and the wound closed, as in blood- letting. 2658. What has been already said (par. 2654) in reference to the pos- sible danger of infusion, applies also to transfusion. If too much blood be injected at once, and too quickly, overfilling and rending of the heart, palsy, and death, may ensue. Magendie has also observed that not merely the entrance of air into the vein, but also of clotted blood, may cause death by stopping up the minute vessels of the lungs. According to Bickersteth (a), transfusion should, where possible, be undertaken before the circulation in the patient's arm has entirely ceased. 2659. The following is the mode of proceeding in mediate transfusion. A sufficiently large superficial vein, the vena cephalica is best, must be laid bare, by a cut an inch and a half long, upon a fold of skin ; the vein is to be cleared from the cellular tissue, and two threads carried round it, of which the one corresponds to the upper, and the other to the lower angle of the wound. The threads are now to be tied, and whilst with (a) Liverpool Medical Journal. 1834. May.—London Medical Gazette, vol. xiv. p. 599. OF CAUTERIZATION. 629 them the vessel is a little raised, it is opened with the lancet. The canula filled with warm water, is now passed into the vein, and the upper thread tied over it, the lower thread remaining tied. Whilst this is doing, the person from whom the blood is to be taken, standing close to the patient, has a vein opened with a large wound, the blood is received into a warm vessel, and the syringe, also warmed, draws up of it about twro ounces. The point of the syringe is now quickly directed upwards, a little blood squirted out to get rid of the air, and it is then fixed into the canula in the vein, and the blood slowly injected through it. The syringe should not be completely emptied, because the remaining blood in it quickly clots. The syringe is now to be cleared with warm water, and the in- jection repeated, for which purpose the vein, which in the mean while has been compressed, must now be re-opened, and blood drawn into a cup as already mentioned. After the lapse of five minutes, more blood may be thrown in according to circumstances. The dressing and after- treament are to be managed exactly as in infusion, (par. 2635.) Blundell's apparatus consists of a funnel for receiving the blood, connected by a tube with the syringe which injects the blood into the vein through an elastic tube. It is not proper, because the blood easily clots in it. Instead of a syringe holding two ounces, Blasius thinks a smaller one holding not more than half an ounce, is better, as therewith the blood loses less of its vitality, and clots less. John Muller proposes, after separating the fibrous parts from the blood by beat- ing, to inject it warmed, as in this way it still retains its corpuscles and living powers. VII.—OF CAUTERIZATION. CosT-ffius, de Igneis Medicinae Praesidiis. Venet., 1593. Fienus, De Cauteriis. Leovan, 1598. Severinus, PyrotechniaChirurgica; inhisDe Efficaci Medicinae, p. 143. Francof., 1646. Recueil des Pieces, qui ont concouru pour le prix de l'Academie de Chirurgie, vol. iii. Pouteau, Memoire sur les Avantages du Cautere Actuel; in his Melanges de Chirurgie, p. 1. Loder, Ueber das kiinstliche Brennen; in his Medic.-Chirurg. Beobachtungen, vol. i. p. 230. Pascal., Ueber die Wirkungen des Brennens mit Moxa; in neuster Sammlung der bester Abhandlungen fur Wundarzte, vol. ii. p. 302. Percy, Pyrotechnie Chirurgicale Pratique. Paris, 1810. > Valentin, L., Memoire et Observations concernant les bons effets du Cautere Actuel. Nancy, 1815. Larrey, De l'Usage de Moxa; in Recueil de Memoires de Chirurgie,p. 1. Paris. 1821. Baerwinkel, Dissert, de Igniis in Arte Medicina. Lipsiae, 1824. Klein, Uber die Anwendung des gliihenden Eisens; in von Graefe und von Walther's Journal, vol. iii. part iv. p. 605. Wolff; in same, vol. v. part. iii. von Kern, V., Ueber die Anwendung des Gliiheisens bei verschiedenen Krank- heiten. Wien, 1828. 2660. Under the term Cauterization, is included the more or less se- vere application of escharotics or of fire on any part of our body. Escha- rotics, (Cauteria potentialis, Lat.; Aetzmittel, Germ.; Causlique, Fr.,) of which those most in use are lunar caustic, caustic potash, Cosme's powder, corrosive sublimate and butyr of antimony, are applied either in 630 KINDS OF CAUTERIZATION ; THE ACTUAL CAUTERY. a dry form, or as powder made into a paste with a little fluid, or in a fluid form, the mode of using which on luxuriant granulations has been already noticed (par. 2352, and frequently elsewhere.) Fire {Ignis, Lat.; Feuer, Germ. ; Feu, Fr.) is applied either with the actual cautery (Cau- terium actuate) or by combustible substances, {Moxa, Lat.; Brenncylinder Germ.,) which are allowed to burn on the surface of the body. 2661. The object of cauterization is generally very various, and may be, first, the destruction of a part; second, alteration, change, or excite- ment of the living activity of any one part, whereby a more speedy con- version of its substance, a more active absorption and the dispersion of tumours is effected ; third, a greater degree of inflammation ; fourth, re- moval of a deep-seated process of disease to the surface of the body ; fifth, destruction of hurtful matter; sixth, stoppage of bleeding, especially that of the so-called parenchymatous. In consequence of these various effects of cauterization it is employed in a great many diseases, for instance, in fungous growths, in cancer, moist and secreting parts, in teleangiectasy, in cold abscesses, in deep-seated, rheumatic and gouty affections, in the several diseases of joints, in palsy and other nervous affections, in deep- seated suppuration and.the like. 2662. It must be remarked, in reference to the effect of Cauterization by escharotics and by fire, that the former always causes destruction of the part on which it is applied, bu{ little alters the vitality of the neigh- bouring parts, and is only specially effective from the suppuration set up in the cauterized part. Hence its use, if the destruction of the part be not the object of its application, is specially confined to those parts where a discharge is to be kept up for a long time. The operation of fire acts more deeply upon the neighbouring parts, sets up greater reaction, excite- ment of the living activity, quicker change of substance, violent contrac- tion of muscles, and independent of those cases where its object is the destruction of any part or the formation of a slough, may be considered in many other cases as a powerful remedy for the purpose, after the sepa- ration of the slough formed by the burn, of keeping up long-continued suppuration. 2663. The Actual Cautery may be employed at various degrees of heat; it may either be held at a distance of five or six inches, and brought gradually nearer and nearer to a part, or it may be moved freely upon the surface of a part, or it may be kept in contact with it for some time. According to these degrees in the application of the actual cautery do its effects vary, and in the latter case is it very effectual and exciting. 2664. Of the various forms of cautery irons the following are most useful, and if of different size answer all purposes, *. conical, £. flat. round, y. prismatic or hatchet-shaped. The conical iron is specially used where one particular small part is to be acted on, for instance in bleed- ings; the round, where the effect is to be greater and a permanent issue is to be formed ; the prismatic or hatchet shaped, for quickly passing over any part. If the actual cautery be used in any one cavity, or with- out subjecting the neighbouring parts to the effect of the fire, either a conical iron with a sheath must be Employed or a red-hot trocar, which is to be carried to the part required in its own sheath. 2665. When the actual cautery is made use of, special care must be taken that the patient be held fast; and the part to which it is applied CAUTERIZATION BY THE MOXA. 631 must be carefully dried, and if hairy the hairs must be removed. The iron should be white-hot. When the object is to destroy a part, to stanch a bleeding^ or to form an issue, it must be applied efficiently and pressed down with requisite force. If the iron cool and the object be yet unat- tained, a second white-hot iron must be applied. If the cautery be applied in stripes, the stripes should be first marked, should not go from the same point, should not cross, should be an inch and a half to three inches asunder, and the white-hot prismatic or hatchet-shaped iron should be carried in the direction of these stripes with due care over the skin, be- cause it very easily slips from the proper direction. Klein's double cautery iron much facilitates this operation. The parts to be avoided in applying either the actual cautery or the moxa are the skull, where covered only by the pericranium and skin, at least the cautery must not be applied here above a couple of seconds, otherwise its effect will be propagated to the membranes of the brain and the brain itself, the ridge of the nose, the eyelids, the course of the larynx and windpipe, the breast-bone, the breast-glands, the white line of the belly, the superficial tendons, the generative organs, and those parts of joints where, on account of the superficial situation of the capsular ligament, injury to it may be dreaded (a). 2666. After the actual cautery has been applied, the part must be co- vered with lint, dry and spread with some simple ointment. If the pain following be very severe, it may be relieved with anodyne applications. The patient must be kept quiet, and according to circumstances, take antiphlogistic or narcotic medicines. When the slough separates, the suppurating part must be dressed with ointment which will promote its healing, or the suppuration must be kept up as the case requires. If the cauterization have been made on account of bleeding, the early dropping off of the slough must be carefully avoided. 2667. The Moxa is a cylinder of cotton held together with a linen bandage and a few stitches, about an inch high, and of larger or smaller extent, according to the condition of the part to which it is to be applied, and the effect it should produce. The cotton must not be too tightly compressed, and the part on which the moxa is placed must be quite flat. To fix the moxa, a moxa-holder (b) is best employed, to wit, a metallic ring with wooden feet and handle. The neighbouring part where the moxa is applied must be covered with moist compresses to protect them from the sparks which fly about, as when lighted it must be blown with a pipe so as to keep it properly burning; but if its effect be not required to be violent, it may be left to burn without blowing. A special and very convenient kind of moxa may be made with rotten phosphor- escent wood, properly dried and powdered, and mixed up into a paste, with alcohol, which being forced into a mould, may be formed into a cylinder as thick as a quill; this when dry may be cut into pieces half an inch long ; the end of each must be smeared with some digestive ointment to stick it to the skin, and its upper end must be lighted. It burns without any blowing, and its small size permits its application at any part and in any quantity (LarRey.) According to Percy, moxas are best made from the pith of the sunflower (Heli- anthus annuus) rolled up in cotton, soaked in a solution of saltpetre, or in alternate layers of soft tow or fine cotton, which have been some time soaked in a solution of saltpetre, two drams to a pint of water. Both kinds of moxa have the advantage, like the former, of burning without blowing (c). (a) Larrey, above cited, p. 6, pi. xi. fig. 1, 2. (b) Larrey, above cited, pi. i. fig. 3, 4. (c) von Grafee und von Walther's Journal, vol. iii. p. 491. 632 DIVISION OF NERVES IN NEURALGIA. Very useful moxas are made of firm English blotting paper, repeatedly dipped in a solution of chroma te of potash, one part to fifteen parts of water, and dried. A piece of this paper is to be rolled up, and kept together by a needle thrust through it. It burns quickly and regularly. If the part burnt with a moxa be touched with caustic ammonia, the slough is not thrown off by suppuration, but gradually scales off (Larrey.) 2668. The slough thus formed is to be covered either with folds of soft linen, or if its separation and the formation of an issue be required, with a pledget spread with digestive ointment; in the latter case, after the slough has been thrown off, the suppuration is kept up, either by fre- quently touching with caustic, or by inserting a pea, which is first to be fixed with sticking plaster and a bandage, till it form itself a pit. 2669. The difference between the effect of a moxa and of the actual cautery is, that in the former, the sensation of a certain warmth is gradu- ally increased to a violent degree of pain; hence it extends its operation to the deeper tissues, and consequently is to be preferred in affections of deep-seated organs, to the actual cautery. Larrey (a) also supposes that the moxa, besides its relative quantity of heat, communicates to the neighbouring parts a volatile, very active principle, which is produced by the burning of the cotton (b). VIII.—OF THE DIVISION OF NERVES IN NEURALGIA. Haighton, John, M. D., A case of Tic Douloureux, or painful affection of the Face, successfully* treated by a division of the affected (infraorbitar) nerve; in Medical Records and Researches, p. 19. London, 1798. 8vo. Langenbeck, Tractatus Anatomico-Chirurgicus de Nervis Cerebri in dolore Faciei consideratis. Gotting., 1805. Klein, Ueber die Durchschneidung der Nerven bei dem Gesichtsschmerze ; in von Siebold's Chiron, vol. ii. part ii. Leydig, Doloris Faciei dissecto Nervo infraorbilali profligati Historia. Heidelb., 1807. van Wy, Von der Durchschneidung des unteren Augenhohlennerven; in Samm- lung auserlesener Abhandlungen fur praktische Aerzte, vol. iii. p. 463. Abernethy, John, On the Tic Douloureux; in his Surgical Works, vol. ii. p- 203. Edition of 1815. Murray, Essay on Neuralgia. New York, 1816. Klein, Ueber die MogHchkeit der Zerstorung der Gesichtsnerven bei seinem Austritte aus dem Schadel; in von Graefe und von Walther's Journal, vol. iii. p. 46. Eggert, Ueber das Wesen des Gesichtsschmerzes und die Operation desselben; in same, vol. vii. part iv. p. 538. Bonnet, Traite des Sections tendineuses et musculaires, etc.; suivi d'un Memoire sur la Neurotomie souscutanee, p. 622. Paris et Lyons, 1841. Mayo, Herbert, Outlines of Human Pathology. London, 1836. 8vo. 2670. In stubborn neuralgies, which withstand all internal and external treatment, specially those which are seated in the branches of the nerves of the face, the division of the trunk is the only remaining remedy. The result of this operation is generally doubtful, as, although momentary re- lief from pain follows it, the disease returns, which1 is explained by the (a) Above cited, p. 7. Sch'ica, Indolent Tumours, &c. London, (6) Boyle, J., Treatise on a modified ap- 1826. Second Edition.—Wallace, Wil- plication of Moxa in the Treatment of Stiff liam, M. D., A Physiological Enquiry re- and Contracted Joints, and also in Chronic specting the action of Moxa, tic. Dublin, Rheumatism, Rheumatic Gout, Lumbago, 1827. DIVISION OF NERVES IN NEURALGIA: 633 numerous ramifications of the nerves spreading on the face, but is kept up by the union of the divided nerves, on which account it has been re- commended to cut out a piece of the nerve, and to employ cauterization. In recent times, however, the subcutaneous division of nerves has been proposed. (Bonnet, Dieffenbach, and ofhers.) 2671. In frontal neuralgy where the supraorbitar branch of the fifth pair of nerves is affected, the pain begins in the supraorbitar hole, spreads over the forehead, the hairy part of the head, downwards into the orbit, to the inner corner of the eyelids, and frequently over the whole side of the face. The supraorbitar nerve should be cut through transverselv, in doing which the soft parts, above the supraorbitar hole, must be divided down to the bone with a bistoury, and lint thrust into the wound, which should heal by suppuration and granulation. In the subcutaneous division of the inner and outer branches of the frontal nerve, the skin should be pierced about an inch from the middle line, and the third of an inch above the eyebrow, with the tenotome thrust in downwards and outwards, and carried an inch or an inch and a half further beneath the skin; the instrument is then held steady with its cutting edge forward, and the skin pressed several times with the thumb of the other hand, so as to cut through the parts beneath it. To make more sure that the nerve do not escape, the edge of the knife must be turned back so as to divide the soft parts down to the bone. If the inner branch of the nerve have to be divided, the knife after being withdrawn, must again be introduced into the wound, turned inwards and downwards, and the division-made in the same way. 2672. In the case of an infraorbitar neuralgy, (Fothergill's (a) Face- ache,) where the pain begins at the outlet for the infraorbitar nerve, and spreads over the wings of the nose, the cheek and upper lip of one side, the infraorbitar nerve must be divided. This must be done by thrusting a pointed bistoury half an inch below the under edge of the orbit, and half an inch from the inner corner of the eye, directly down towards the cuspid tooth, to the bone, and carried outwards, and downwards three quarters of an inch towards the zygomatic process of the upper jawbone. The wound is to be treated as in the former case. In the subcutaneous division cf the infraorbitar nerve, that part of the skin is first chosen which corresponds to the infraorbitar hole; about half an inch from which outwards and the same distance below the edge of the orbit, the skin is to be pierced. The upper lip must be drawn downwards and forwards with the left hand, to render the nerve tense and separate it from the cuspid pit. The tenotome with its edge upwards, is introduced with the right hand, and cuts cautiously inwards and a Httle downwards, that it may sweep the bottom of the cuspit, till it reach the infraorbitar hole, and stop on the nasal eminence. The edge is now directed a little forwards and divides the nerve by a lever-like movement, the knife being always kept close to the bone. 2673. When the face-ache spreads from the middle of the parotid gland towards the wing of the nose and lower eyelid, towrards the corner or the mouth and upper lip, or also even towards the chin, the teetK, and angle of the lower jaw, the middle branches of the infraorbitar and inferior maxillary nerves, or even the lower branches of the facial nerve and the mental nerve are affected. In the former case, for the division of the middle branches of the facial nerve and the infraorbitar nerve, Klein makes a cut from about the (a) Fothergill, J„ M. D., Of a painful Affection of the Face; in Medical Observations and Inquiries, vol. v. p. 129. London, 1776. Vol. iii.—54 634 DIVISION OF NERVES IN NEURALGIA. middle of the nose to the middle of the cheek. In the second case, he makes a cut into the cheek through the m. masseter to the under edge of the lower jaw, and beneath it towards its angle. The parotid duct must be avoided. The bleeding from the facial artery must be stanched by thrusting in lint and by a compressing bandage. When the pain extends from the hinder angle of the lower jaw to the upper lip, towards the ear, the nose, and eyelid, when especially thelower facial nerve and consecutively the mental and infraorbitar nerves are affected, a cut should be made for dividing the facial nerve, which according to Klein, should begin below the parotid duct at the edge of the m. masseter, pass along the under edge of the lower jaw, and run up to the corner of the mouth. If the inferior maxillary nerve be the seat of the neuralgy, and the pain extend from the second molar tooth over the lower jaw, and the teeth towards the ear and eye, the inferior maxillary nerve must be cut through, for which purpose the membrane of the mouth and gums is to be divided, and the knife passed directly from the second molar tooth to the base of the lower jaw, down to the bone. If this be insufficient, the nerve may be divided at its entrance into the maxillary canal, by cutting vertically near the coronoid process, and then, by scarification with a gum-lancet between that process and the m. pterygoideus (a). 2674. For the subcutaneous division of the nerves of the cheek, Dief- fenbach passes a tenotome in various directions beneath the skin, and divides the affected nerves with successive strokes. In mental neuralgy, for the subcutaneous division of the nerve, at its escape from the mental hole, the skin covering the lower jaw must, according to Bonnet, be pierced half an inch from the symphysis, and the same distance from the lower edge of the horizontal branch of the lower jaw. The tenotome is introduced with the right hand, whilst the lower lip is held with the first three fingers of the left hand, the thumb and middle finger being placed on the outer surface, and the forefinger on the mucous membrane at the first molar tooth, the lower lip- drawn forwards and upwards, and the nerve separated a little from the bone. The tenotome, with its edge downwards, is passed backwards and upwards till its point which should run along the bone, and always touch it, reach the first molar tooth, and be felt by the forefinger beneath the mucous membrane. The edge of the tenotome is now pressed down, by raising the handle, and drawn a little back ; and this movement is repeated several times, whilst the edge of the knife is carefully kept on the upper surface of the bone. If this operation be performed on the right side, the left hand must be carried round the head of the patient, and the lip held with three fingers, whilst the thumb rests on the inside. 2675. As even the repeated division of the nerves of the face, accord- ing to these rules never affords complete relief, and the pain recurs, Klfin was first struck with the idea of destroying the trunk of the facial nerve at its exit from the stylo-mastoid hole. After various experiments which he performed on the dead body, for the division of the nerve at the part he had thought of, he performed the operation in the following way. He (a) Klein, above cited, in the Chiron.—Lizars, Neuralgia of the Inferior Maxillary Nerve cured by Operation; in Edinburgh Medical and SurgicalJo urnal, vol. xvii. p. 52a. 1821. DIVISION OF NERVES IN NEURALGIA. 635 made a deep penetrating cut with a slightly-curved bistoury, which he thrust in, below the lobe of the auricle, well up-pulled, towards the front edge of the mastoid process, obliquely behind it, to its extremity. The divided occipital artery bled smartly, but was checked by an assistant pressing on the carotid. He then made a transverse cut below the lobe of the auricle, separating it from the beginning of the first cut to the tem- poral artery, which he avoided, and immediately some trifling auricular branches spouted forth. He then separated the flap in the same way deeply to the hinder edge of the styloid process throughout its whole length, at the same time thrusting the point of the knife deeply upwards and backwards, and lengthening the cut also behind the mastoid process down to the bone. Herewith the facial nerve was cut in two. He now quickly pushed a hot blunt round cautery iron as thick as a common quill, obliquely from below upwards and inwards, pressed it firmly and for some time on the stylo-mastoid hole, and carried it in different direc- tions for the purpose of cauterizing the occipital artery. The wound, which still continued bleeding, was plugged with lint dipped in white of egg and strewed with gum arabic, covered with a compress, the whole fastened with a cloth around the head, and pressure kept up several hours, by an assistant 2676. No remarkable symptoms occurred after the operation, and the wound healed in a short time. Wryness of the mouth and tip of the nose, which occured on the destruction of the nerve, subsided, and the face-ache completely ceased. In a second case, which Klein operated on, the result was the same, and the patient had no inconvenience beyond a slight mark. In both cases, however, according to positive assurances, the result was not permanent. Klein considers the operation entirely free from danger. If the division of the facial nerve be properly managed, the carotid artery and jugular vein cannot be wTounded, as the fromer lies in its canal too far from the styloid process, and the latter is distant from the place of the cut, and if wounded, can be commanded by pressure (a). According to Langenbeck, the division of this nerve can be performed with great safety in the following manner. The auricle being drawn upwards and forwards, a cut is made from the front edge of the root of the mastoid, process, where it is con- nected with the styloid process, and continued below the auditory passage, on the front edge of the m. sterno-mastoideus, so that its tendinous fibres can be seen. The parotid gland now laid bare is carefully separated and turned aside ; and the wounded. posterior or occipital artery tied. The finger is now passed to the upper part of the wound, and feeling the junction of the bony auditory passage, and the root of the styloid process as a broad bony surface, is pushed on towards the upper edge of the mastoid process, behind it, but stopping at the hind edge of the styloid process, without reaching its inner side, then from the inner edge of the base of that process and the m. sterno-mastoideus, from above downwards, and from without inwards, towards the styloid process, where it tears away the cellular tissue covering the nerve, which then appearing as a white cord above the hinder belly of the m. digas- tricus maxillae inferioris, is taken hold of with the forceps, lifted up a little and cut through, or a piece of it taken out. 2677. On comparing the subcutaneous division of nerves with the ordinary mode of proceeding, it cannot be denied, that the complete division of the nerve in every case is more difficult, and the nerve may (a) Frieker, Dissert, de Secundo Trunco Nervi Duri in Prosopalgia. Tubing., 1813.— Klein, above cited. 636 OF AMPUTATION OF THE LIMBS. even be missed. This, however, can be avoided by careful performance of the operation, founded on correct anatomical knowledge. The symp- toms are usually slight, as in all subcutaneous operations, and the blood which has been thereby extravasated is soon absorbed. Bonnet has attempted to contravert the objection, that the divided nerve reunites, by stating, that after its division the extravasated blood remains between the ends of the nerve, and that, afterwards, one part of it is absorbed, and the other becomes organized, and forms a connecting intermediate substance between them. Whether otherwise, by the sub- cutaneous division of the nerve, the result is rendered more certain, still remains undecided by the experience hitherto had. It must not, how- ever, be overlooked, that several cases which have been related as sub- cutaneous neuro-myotomies, have produced painful and spasmodic con- tractions of the muscles (a); or it may be doubted whether the trunk of the nerve, or only some little branches of it have been divided {b). The following may be mentioned as examples of the division of nerves, and at different parts. ° Delpech and Earle have cut directly through the ulnar nerve, where it runs behind the inner condyle. Astley Cooper cut out half an inch of the radial nerve, after laying it bare on the radius. Abernethy and Wilson di- vided, above the injured part, a nerve wounded in bloodletting. Abernethy cut out half an inch of the digital nerve on the middle joint of the finger. Malagodi cut out a semilunar piece, of a finger's breadth, from the ischiatic nerve in the re- gion of the knee-joint. Swan cut through the peroneal nerve, at the inner edge of the outer hamstring; Delpech divided the posterior tibial nerve, whilst on the hinder edge of the shin-bone, laying it and the vessels bare, and separating it from them. Manovy divided the same nerve behind the inner condyle, in a case of traumatic trismus. Bujalsky cut off both from the outer branches of both the acces- sory nerves of Willis, at their exit from the m. sterno-mastoideus, a piece three inches lono-, but without any satisfactory result. In pains in the heel, accord- ing to Lentin, deep cuts have been made into the heel, and suppuration kept up in them for a long time. From the energetic application of the actual cautery in plantar neuralgy, I have seen the most satisfactory result. IX—OF AMPUTATION OF THE LIMBS. (Amputatio Membrorum, Lat.; Ablosung der Gleider, Germ.; Amputation, Fr.) Sharp, Samuel, A Treatise of the Operations of Surgery, &c. London, 1761. Eighth Edition. Ibid., A Critical Inquiry into the present state of Surgery. London, l/ol. Fourth Edition. , . , . Louis, Memoire sur l'Amputation des grandes Extremites; in Memoires de l'Acad. de Chirurgie, vol. ii. p. 268, p. 355. Paris, 1761-74. 4to. Bromfield, William, Chirurgical Observations and Cases, vol. l. p. 38. Lon- don, 1773. 8vo. Pezold, De Amputatione Membrorum. Gotting., 17/8. Larrey, Memoire sur les Amputations des Membres. Paris, an v. Alanson, Edward, Practical Observations upon Amputation, and the After- Treatment. London, 1779. 8vo. Kirkland, T., Thoughts on Amputation, &c. London, 1780. Svo. Mynors, R., Practical Thoughts on Amputations. Birmingham, 1783. 12mo. Pott, Percival, Remarks on the necessity and propriety of Amputation, &c; in his Chirurgical Works, vol. iii. p. 351. Edition of 1783. (a) Sperino. Casimirino, Neuralgie grave in Gazette Medicale de Paris, voLix. p. 205. de plusieurs rameaux du plexus cervical, 1843. gueri par la Neuro-Myotomie souscutanee; (b) Rivieri, above quoted, p. 496. KINDS OF AMPUTATIONS. 637 Bell, Benjamin", A System of Surgery, vol. vi. p. 301. Edinburgh, 1783.. van Hoorn, Spec, de iis, quae in partibus membri, praesertim osseis, amputations vulneratis notanda sunt. Lugd. Batav., 1803. Schreiner, Ueber die Amputation grosser Gliedmassen nach Schusswunden. Leipzig, 1807. Desault, Sur I1 Amputations des Membres ; in his GSuvres Chirurgicales, vol. ii. p. 531. Edition of 1812. Graefe, Normen fur die Ablosung grosserer Gliedmassen. Berlin, 1812. Larrey, Memoires de Chirurgie Militaire et Campao-ne, vol. ii. p. 451. Paris, 1812-17. 8vo. " Benedict, Einige Worte uber die Amputation in Kreigspitalern. Berlin, 1814. Roux, Memoire et Observations sur la reunion immediate de Ja Plaie apres l'Am- putation circulaire des Membres dans leur continuite; suivis du Rapport fait a l'In- stitut par M. M. Percy et Deschamps. Paris, 1814. Ibid., Relation d'un Voyage fait a Londres, p. 336. Paris, 1814. 8vo. Guthrie, G. J., On Gunshot Wounds of the Extremities requiring the different Operations of Amputation; with their After-Treatment. London, 1815. 8vo. Klein, Praktische Ansichten der bedeutendsten chirurgischen Operationen. Part I. Stuttgart, 1816. Hutchison, A. Copeland, Practical Observations in Surgery. London, 1816. 8vo. Ibid., Some further Observations on the subject of the proper period for ampu- tating in Gunshot Wounds, &c. London, 1817. 8vo. Brunninghausen, Erfahrungen und Bemerkungen iiber die Amputation. Wurz- burg, 1818. Maingault, Medecine Operatoire ; Traite des diverses Amputations qui se pra- tiquent sur le Corps Humain, representees par des figures dessinees d'apres nature et Jithographiees. Paris, 1822. fol. Averill, Charles, A short Treatise on Operative Surgery, p. 107. London, 1823. sm. 8vo. First Edition. Kern, Ueber die Handlungweise bei Absetzung der Glieder. Wien, 1826. Se- cond Edition. Hennen, John, Principles of Military Surgery. London, 1829. Third Edition. Dupuytren, le Baron, Lecons Orales de Clinique Chirurgicale, vol. iv. p. 233. Paris, 1834. 8vo. Sedillot, De l'Amputation des Membres dans la continuite et la contiguite, ses avantages et ses inconveniens. Paris, 1836. Syme, James, Principles of Surgery. Edinburgh, 1837. Second Edition. Liston, Robert, Elements of Surgery, p. 760, part. ii. London, 1840. Second Edition. Alcock, Rutherford, Lectures on Amputation; in Lancet. 1840-41; vol. i. and ii. Schaeffer, H. J., Dissert, de Cultris Amputatoriis. Bonnae, 1842. Fergusson, William, A System of Practical Surgery. London, 1846. Second Edition. Pelletan, Memoire sur 1'Amputation des Membres; in Clinique Chirurgicale, vol. iii. p. 183. Chelius, Ueber Amputationen ; in Heidelb. klinischen Annalen, vol. i. part i. Jaeger, Article Amputatio; in Handworterbuch der Chirurgie, vol. i. p. 157. Malgaigne, Manuel de Medecine Operatoire, fondee sur 1'Anatomie pathologique, et 1'Anatomie normale. Paris, 1843. Fourth Edition. [Mann, J., Observations on Amputation at the Joints, in New York Med. Repository, vol. 7, 1822; and in Sketches of the Campaigns of 1812, 13, 14, in Canada, &c. Dedhara, 1816. Hubbard, On Amputation at the Joints, in the same Journal, vol. 7. Davidge, Physical Sketches. Baltimore. 8vo. Smith, N. R., Surgical Memoirs. Baltimore, 1831. 8vo. Geddings, E., Article Amputation, in the American Medical Cyclo- pedia, vol. i. Philadelphia, 1834. 8vo.—g. w. n.] 54* 638 COMPRESSION OF ARTERIES WITH THE TOURNIQUET. 2678. Amputation is the last and most grievous remedy to which art can have recourse, for the purpose of saving the life of a patient by the loss of a limb. The cases which make it necessary have been already mentioned in treating of gunshot wounds, {par. 346,) compound frac- tures, (par. 590,) white swelling,{par. 254,) carious ulcers, {par. 886,) and elsewhere. 2679. Amputations may be distinguished into those which are per- formed in the continuity of the limbs, {Amputationes,) and those at joints (Exarticulationes.) 2680. The following points must be considered of amputations in ge- neral ; first, the precaution against bleeding ; second, the formation of such wound that the bone may be properly covered with soft parts; third, the sawing off the bone ; fourth, the stanching the bleeding from the divided vessels; and fifth, the proper treatment of the wound formed by amputation. 268.1. Precaution against bleeding consists in the compression of the principal artery of the limb to be amputated, either by the application of the tourniquet, (par. 283,) or by the fingers of an assistant, or with a proper compressor. The application of the tourniquet is accompanied with many incon- veniences, as if it be placed in the neighbourhood of the part where the amputation is to be performed the muscles will not retract properly ; it is often inconvenient to the operator, and prevents the return of the blood through the veins. For these reasons compression of the principal artery by a capable assistant, at least in amputation of the upper limbs and thigh, is preferable to the tourniquet. In amputation of the leg the tourniquet is used, because here tying the ligatures is often difficult, and the assistant compressing the vessel becomes exhausted. Compression must always be made at a spot where the artery is superficial, and the neighbouring bone affords a point of support (par. 284.) In patients who are weak and have little blood, Bru\nninghausen recommends, that before the operation the limb should be swathed in a flannel bandage nearly up to the place of the cut, in order to diminish the loss of blood. [The only real advantage derived from the use of a tourniquet at an amputation, except in cases of compound fracture or wounds, where it had been previously ap- plied to check bleeding, is, that the operator has no dread of a gush of arterial blood when he cuts through the large vessels, if he have any doubt of the capability and firmness of the assistant, to whom compression of the principal artery is intrusted. But if he be trustworthy, the compression is more certainly made with the fingers than with the tourniquet, the pad of which, however well adjusted, will often slip from the vessel if the patient struggle, and become quite useless. One would think compression could scarcely be objected to, in amputations of the smaller parts of the limbs, when it is invariably and necessarily employed in amputations high up through the thigh and upper arm and at the hip and shoulder, and no difficulty is found in practising it at either of those parts. Chelius has justly objected to the tourniquet, that it prevents the return of the blood by the veins, a circumstance too little remembered in amputation. Bleeding from the arteries is, in general, cautiously guarded against; but bleeding from the veins is thought of no importance, and by some indeed actually advantageous, which is however a most serious mistake. It must not be supposed that when the tourni- quet is applied, all flow of blood to the part of the limb below is stopped, for such is not the case, as is decidedly proved by the filling almost to bursting of the super- ficial veins, and the generally congested state of the whole part, in consequence,of which directly the knife begins to cut, the blood streams forth in torrents, frequently with the observation that it is only venous blood, forgetting that this venous blood AMPUTATION BY THE CIRCULAR CUT. 639 must be so much withdrawn from the general circulation, of which the patient not unfrequently soon feels the effect, becomes pallid and covered with cold sweat and now and then swoons. All this depends on the tourniquet bandage which has dammed up the current from below, without any possible benefit. But admitting for argument's sake, that a free flow of venous blood at an amputa- tion is generally advantageous, which, however, I agree with many others in deny- ing, yet there are occasions and those not unfrequent, where it is positively danger- ous and occasionally fatal to the patient. A healthy person who, by wound of, or from severe tearing or compound fracture of a limb, has lost a considerable quantity of blood, and has been so completely pulled down by it, that it is often necessary to administer stimulants and wait for hours till his circulation have recovered, and the immediate effect of the bleeding have gone off, such person cannot bear to lose any blood, and the operator must take every precaution, and it may be even tie the principal artery before amputating, for the purpose of guarding against loss of blood. Neither can a patient who is on the very verge of hectic, the result of any local dis- ease or excited during the progress of a severe injury, bear any loss of blood during an amputation; three or four ounces of venous blood suddenly escaping may be fatal, or endanger him very considerably. For these reasons bleeding from the veins is not to be thought lightly of, and therefore compression by the thumbs is better than the tourniquet, as*it checks the great flow of blood to the limb, and does not prevent the leturn, by the veins, of that blood which has made its way by the side channels, which cannot be closed more by the tourniquet than they are by the thumbs. Some surgeons advise tying the -principal artery first before amputating, if the limb be removed near the trunk, and it cannot be doubted this is the safest method; I have done this on two or three occasions; but at other times have taken up the artery directly it was cut through and afterwards finished the operation, and upon the whole I think this is the better practice of the two, when there seems to be a necessity for either.—j. f. s.] 2682. The formation of such wound that the bone can be properly covered with soft parts, it has, in general, been attempted to effect in two ways, a. by cutting circularly into the soft parts down to the bone, or Amputation by the circular cut {Amputation durch der Zirkelschnitt, Germ.; Amputation circulaire, Fr.); and j3. by separating the soft parts from the bone in shape of a flap, or Amputation with a flap (Lappen- amputation, Germ. ; Amputation a lambeaux, Fr.) 2683. History presents many modes of meeting the just-mentioned requirements by the circular cut. Celsus (a) had already expressly directed that the skin and muscles should at one stroke be cut into down to the bone, that they should be wrell drawn up, and be again divided from the bone higher up, so that the bone might be covered and union of the parts, drawn over it, might be effected. At a later period, however, this direction was so considerably departed from, that the skin and muscles being merely drawn up, were divided down to the bone with one circular cut, and the bone sawn off. 2684. The impossibility, by this method, of drawing the divided parts over the bone and covering it, necessarily rendered this a violent pro- ceeding, the suppuration was always considerable, the bone stuck out, or was only partially covered, and a bad scar was formed. For these reasons, various modes were tried to save as much skin and muscular substance as would be sufficient for the due and perfect covering of the stump. 2685. Here belong the various methods of dividing the skin and muscles in different steps and with several cuts. Petit {b) divided the skin with a circular cut down to the muscles, separated it a little more, (a) De Medicind*, lib. vii. cap. xxxiiL (6) Traite des Maladies Chirurgicales, vol. iii. p. 150* 640 AMPUTATION BY THE CIRCULAR CUT. drew it back, cut through the muscles at the edge of the skin so drawn back, and after sawing through the bone, covered the surface of the wound with the skin which had been saved. With this agreed the latter practice of Mynors (a), who considered a pad of flesh unnecessary; he divided the skin with a circular cut, dissected it off to a proper distance, and cut through the mass of muscle vertically down to the bone. Very recently, Brunninghausen (6) has followed a similar practice, except that he does not divide the skin by one circular, but by two semicircular cuts, and dissects them back so as to form two semilunar flaps; the muscles are then cut through vertically to the bone. 2686. For the purpose of making a wound with a conical surface in the upper part of which is the bone, Louis (c) has directed cutting through the skin and superficial muscles with the first cut, to draw them back, and at their edge to cut through the deep muscles down to the bone. Alanson {d) proposed a particular mode of forming a. conical wound surface, to make which when the skin is divided by a circular cut, sepa- rated from the muscles and turned back, the knife must be so placed that its edge is directed obliquely upwards and inwards, and whilst carrying it round the whole limb in this direction, all the muscles are cut through to the bone, so that a hollow wound is formed, at the top of which the bone is sawn off. In practice, however, it is found impossible to carry the knife in a circle round the limb as directed, as it cannot travel except in a spiral line (e). This method, therefore, found but few adherents (/), and was set aside by other manoeuvres, by which a conical wound surface could be formed in the muscular substance. 2687. According to Gooch and Bell {g), .he skin and muscle should be divided with one circular cut down to the bone, then the knife thrust in about an inch higher between the muscle and the bone and carried round, and lastly, the bone sawn through still higher than the cut through the muscles. Desault {Ii) cut through the muscles layer by layer, always allowing one to retract before he cut through another, and so proceeded till he reached the bone. Richter {i) practised a similar method with his fourfold circular cut, in which, with the first circular cut he divided the skin, which he allowed to retract, and at its retracted edge, with three several circular cuts he reached the bone ; in doing this, the divided layer of muscles retracted, and those still remaining were cut through higher up. Boyer (j ) divides the skin with the first circular cut, and by a second half through the superficial muscles, and on their retraction cut through the deep layer, and finishes by dividing with a bistoury the remaining fibres attached to the bone, together with the periosteum. (a) Above cited, p. 19. (g) Above cited, p. 340. (b) Above cited. (h) Above cited, p. 276. (c) Above cited, p. 358. (t) Medicinisch und chirurgische Bemer- (d) Above cited, p. 12. kungen, vol. i. p. 284. (e) Wandenberg, Briefe, vol. ii. part i. p. (j) Traite des Maladies Chirurgicales et 21. les Operations qui leur conviennent, vol. xi. (/) Loder, Programm. De nova Amputa- p. 156. Paris, 1822-26. Third Edition. tione Alansoni. Jenae, 1784. FLAP-AMPUTATIONS. 641 2688. Graefe (a) again takes up Alanson's notion of a funnel-shaped cut with one stroke of the knife, and manages it with a sort of leaf- shaped knife, {Blattmesser,) the blade of which is bellied in front, and becomes narrower and narroweriowards the handle. When the skin has been divided with one circular cut and drawn back, the bellied part of the knife is placed on its edge with the cutting part obliquely upwards carried with a single stroke in this direction around the whole limb, and the muscles are thus cut through to the bone. 2689. Dupuytren (6), for the purpose of diminishing the pain in the division of the skin and muscles, employed Celsus's method (par. 2683.) An assistant drew the skin well back, and he then divided the skin and muscles at one stroke to the bone ; the muscles hereupon retract, and those still remaining attached are cut through higher, so that in this way a conical wound is produced. Wilhelm operates in like manner (c). 2690. In the history of the circular cut the proposals of Valentin and Portal to prevent the projection of the bone must also be mentioned; according to the former, the muscles should each time be cut through in their greatest degree of extension, according to the latter, just the con- trary. 2691. Flap-Amputations were first invented by Lowdham {d) in the seventeenth century ; in amputating the leg, he made, from the calf a pil- low in shape of a flap, for the purpose of covering the stump. Verduin (e) and Sabourin {f) afterwards arrogated this discovery. Flap amputations, restricted by their inventor to the leg, were applied to the thigh also by Ravaton {g) and Vermale (h), and with them commenced Amputation with two flaps. They always made use of flaps, in doing which, the knife was thrust through the whole mass of limb to the bone, carried some dis- tance beyond it, and then the parts divided outwards. Langenbeck {i) forms flaps, either one or two, by a deep cut from without, inwards towards the bone. Upon flap amputations may further be consulted Salzmann, De novo Amputationis Methodo. Argent., 1722. La Faye, Historie de l'Amputation suivant la Methode de Verduin et Sabourin; in Memoires de l'Acad. de Chirurg., vol. ii. p. 243. Garengeot ; in same, p. 261. O'Halloran, A Complete Treatise on Gangrene and Sphacelus; with a new Me- thod of Amputation. London, 1765. 8vo. Siebold, Dissert, de Amputatione Femoris cum relictis duobus carnis segmentis. Wirceb., 1782. 2692. Pott's {k) method must be considered as a compound of the circular and flap operations, he cut into the muscle first on the one, and then on the other side obliquely from below upwards and thus formed a (a) Above cited, pi. vii. fig. 6, 7. (/) Mangetti, Bibliotheca Chirurgica, (b) Sabatier, Medicine Operatoire, vol. iv. vol. ii. p. 255. p. 471. 1824. New Edition.—Dupuytren, (g) Le Dran, Traite des Operations de above cited, vol. iii. p. 233. Chirurgie, p. 564. Paris, 1742. (c) Klinische Chirurgie, vol. i. Munchen, (h) Observations de Chirurgie pratique, 1830. precedees d'une Nouvelle Methode d'Ampu- (d) Young's Currus triumphalis e terebin. tation. Mannheim, 1767. thina. London, 1679. (i) Bibliothek far die Chirurgie, vol. iii. (e) Epistola de nova Artuum decurtando- part ii. vol. iv. part iii. rum ratione. Amstel., 1696. (k) Above cited. 642 VARIOUS MODES OF AMPUTATION. wedge-like wound. Siebold's (a) proposal corresponds to it, and con- sists, after cutting through and drawing back the skin, in making the cut through the muscles obliquely upwards, first on the outer, and then on the inner side, by which a wound is formed as in Pott's method. Here also belongs Schreiner's {b) plan of dividing the skin and muscles with one circular cut down to the bone, and then by cutting upwards on each side with a bistoury to the bone, forming two flaps, which he separated from the bone, and sawed the latter off in the angle. Herewith must also be placed the modes of proceeding which, by Lan- genbeck and Scoutetten, are confined to disarticulations, the oval cut also used in amputating the continuity of the limb, the oblique cut of Sedillot, Baudens, and Malgaigne, the sloping cut of Blasius (c) ; in making which, the soft parts are divided in an oblique surface, or in form of the mouth-piece of a clarionet, or in the form, of A, so that the point of the cut is on the front of the limb, a little above the part where the bone is sawn through, and the rather rounded base is behind and below. Sedillot, Baudens, and Malgaigne, divide in this way, the skin alone, separate it, and divide the muscles higher with a circular cut. Blasius, with a peculiar knife makes two cuts through the soft parts, which both pass obliquely to the long and thick diameter of the limb, and unite at their end, by which a wound is made, presenting an obliquely cut out funnel or cornet, and has close below the place of division of the bone, a re-entering /\ shaped angle to the wound, and two-thirds or the whole of the diameter of the limb lower, a projecting V shaped lip to the wound, which in closing the wound, drops into each corner, but can never be brought directly opposite. 2693. When the muscles have been thus divided down to the bone, they are held back by an assistant wTith a cleft cloth (1), at the edge of which the muscular fibres connected with and also projecting from the bone, and the periosteum, are divided with a circular cut. The left thumb-nail is now placed close to the face of the stump, for the purpose of guiding the saw, which at first and towards the last, when the bone is nearly sawn through, must be moved more slowly, and with shorter strokes (2). Whilst the sawing is in progress, the assistant who holds the limb must not move it either up or down, because in the former case he fixes the saw, and in the latter, breaks the bone. If any bony points remain, they must be cut off with bone nippers, or removed with a file or a fine saw. The cleft cloth to keep the muscles back, is better than the retractors of Bell and Klein. Scraping off the periosteum is superfluous. Walther and Brunning- hausen divide the periosteum by a circular cut about half an inch below where the bone is to be sawn through, and turn it up, so that after the sawing, the end of the bone may be covered by it. They imagine that it promotes union! The saw commonly in use is the bone-saw, or Pott's plate-saw. [(1) 1 do not think there is any great advantage gained by using the cleft cloth, and very rarely employ it; as, by passing the thumb and forefinger on either side of the bone or bones, and pressing the palm of the hand and ball of the thumb against the surface of the stump, the soft parts can be pressed well back, and out of the (a) Salzburar. Med.-Chirurg. Zeitung, tations Methode, u. s. w. Berlin, 1838.— vol. ii. p. 44. " 1812. Handbuch der Chirurgie, vol. in. p. 3i7. (6) Above cited, p. 162. Second Edition.—OprENHEiM'sZeitschriftfur (c) Der Schragschnitt, Eine neue Ampu- die gesammte Medecin. Jan., 1843; p. 10. TYING OF ARTERIES. 643 way of the saw, which should be applied as closely as possible, to the cut ends of the muscles. (2) It will not be superfluous to say a few words about the use of the saw, which is probably one of the worst-used surgical instruments. A good saw should have its teeth well set off, as the carpenter's expression is, that it may neither clog nor hang in its track; and it should have, proportionally to its size,a heavy back, which renders its steadying more easy, and affords all the weight the saw requires to be loaded with. The too frequent mode of using the saw, is to drop its end, whilst the handle is raised, so that when moved it works obliquely ; the operator, at the same time, throwing as much of his own weight as he can conveniently spare upon the handle, as if with the intention of forcing the blade of the saw at one or two strokes through the bone, and then driving it downwards and upwards, as violently and quickly as he can, and often using about as much of the toothed edge as a young violinist does of his fiddle-bow. The consequence is, that the saw works badly, is continually jumping out of its track, makes another, and finishes by splintering the bone, and often cutting through it below where it was proposed. To use a saw pro- perly, it should always, where possible, be held and worked horizontally, moving it forwards and backwards without any pressure of the hand, but allowing merely its own weight to keep it on the appointed place; and as it is moved forwards, even its own weight should be lessened, by slightly supporting, instead of pressing down the saw. After drawing the toothed edge first backwards, and then moving it forwards lightly on the bone, till a shallow track is made, it may be moved freely, so that at least two-thirds, or even more of the saw shall act. The strokes should not be quick, but long; and if so made, four or six of them will cut through the thigh-or shin-bone, more quickly and more cleanly than twice as many short, hurried strokes, and without any risk of splintering the bone, or slipping from the part chosen to saw through.—j. f. s. Liston (a) thinks that working the saw vertically is preferable to horizontally; " for thus, when the section is nearly completed, the uncut part of bone is deep, and less likely to snap on the weight of the limb being allowed to operate, or when undue pressure is made downwards." He thinks, also, that "the regulating of the position of the limb during sawing, should not be intrusted to the assistant alone. He may, from anxiety to facilitate the action of the saw, snap the bone and splinter it, when it has been little more than half divided; or from dread of this, he may lock the instrument, and so delay the completion of the operation. The manage- ment of the lower part of the limb should always be by the person using the saw." (p. 764.) I do not think there is more danger in giving the lower part of the limb to an assistant than the upper; for if the operator hold the lower end, the last portion of the bone is just as likely to be snapped through by the muscles above, when they begin to lose the counterpoise of the limb below, if not specially guarded against. This I have seen, again and again, in amputation through the thigh, that when the bone has been sawn through steadily, and without a splinter, the moment the saw has passed through, up jumps the stump. One point, however, should never be forgotten, to wit, that immediately the soft parts are completely divided, the assistant should grasp the limb below, as near as possible to the place of sawing; and if he have from circumstances, grasped the bone or bones below that which will be sawn through, he should change his grasp, and fix it on the end of the bone just about to be cut through. This specially applies where amputation is performed for diseases of joints, as then the joint is too tender to permit being taken hold of, till its nerves have been divided by the cuts of the operation.—j. f. s.] 2694. After the bone has been sawTn through, the divided vessels must be tied, according to the rules already given (par. 291.) The principal artery is to be first tied, and afterwards the smaller ones. For this pur- pose, it is not necessary to relieve the pressure on the arteries, so that the mouths of the vessels should be seen by the spouting of the blood; anatomical knowledge must here guide the operator. All the spouting vessels having been tied, warm water must be allowed to flow over the (a) Elements of Surgery. 644 AFTER-TREATMENT. wound to ascertain whether there be any little vessel still bleeding. The more carefully the vessels are tied, the less need is there for the applica- tion of cold water, which is generally only necessary when there is trick- ling of blood from vessels which cannot be distinguished, so as to ensure the patient against after-bleeding. _ The best material for ligatures is round, not very thick, but sufficiently strong silk threads ; either both ends of which may be cut off close to the knot, or only one is cut off at the knot, and the remaining one led the nearest way out to the surface of the wound, where it must be fixed to the skin with sticking plaster {par. 293.) What has been already said {par. 297) in reference to torsion, applies here. In the history of amputation, the mode of stanching the blood is of the greatest im- portance, as its well-doing and less danger are in the closest relation With the manner in which the stanching of the blood is effected. Before Ambrose Pare, in 1582, re-employed the separate tying of vessels, already known, from Galen and Aetius, surgeons endeavoured to stanch the bleeding with boiling oil and pitch, into which the stump was plunged, or with the actual cautery; or the amputation was per- formed with a red-hot knife. Tying the arteries at first met with violent opposition, and but few supporters (Guillemeau, De La Motte, and others.) From the absence of precaution against bleeding, together with the unfitting form of the liga- ture instruments, the practice of tying the arteries was very difficult, and the bleeding rendered amputation dangerous, on which account, in many cases, it was not under- taken. Only on the invention of the tourniquet, by Morel, in 1674, and its improvement by Petit, in 1718, did amputation become more general. For the stanching of bleeding, however, the vitriol button, actual cautery, the stick, and tourniquet, were still used in preference. The dread of cutting through the artery in tying it when isolated, led to tying the artery and passing the ligature through it, till this, as well as all the earlier modes of stanching the.blood, yielded completely to tying the vessel alone. It is incomprehensible that in the present time there should still be some, who, instead of the simple and safe practice of tying, employ the constant application of cold water; or in flap-amputations, the compression of the principal arteries in the flap against the bony stump and even recommend it (a). [The bleeding after an amputation is not always from the arteries, but sometimes though the arteries have been tied, and the tourniquet taken off, and sometimes when the tourniquet has not been used, the larger veins pour out, and will not be stopped, as they usually can be by pressure for a few minutes with the finger. Under such circumstances, they must be tied without hesitation, and generally no evil results follow. One of my late colleagues, Tyrrell, always tied the veins at once, if they seemed disposed to bleed. 1 have tied the femoral vein many times, and in but a single case with ill consequence; the patient had inflammation and pus in the iliac vein; but as this occasionally happens, without a ligature having been applied, it may be questionable, whether the ligature was the cause of the mischief or not.—j. f. s.] 2695. When the vessels are all properly tied, after the wound is cleansed from blood, and the surrounding parts are dried, the dressing must be proceeded with, which effects the cure of the wound, either by quick union, or by suppuration and granulation. Many surgeons leave the wound open from six to ten hours, and during this time cover it with sponge or compresses, dipped in cold water, for the purpose of thus guarding against after-bleeding. Dupuytren (b) specially advised this mode o treatment, and followed it in all cases. The advantage of this proceeding is, that if an after-bleeding ensue, the vessel can be at once tied. Small retracted vessels, generally, do not bleed, even if some time be occupied with the operation; they are retracted among the spasmodically contracted parts, but some hours after when this (a) Koch, De prrestantissima Amputa- Journal fur Chirurgie und Augenheilkunde tionis methodo. Landsch., 1826. On the vol. xii. p. 18. contrary, compare von Graefe; in his (b) Above cited, p. 411. TREATMENT AFTER AMPUTATION. 645 condition subsides, or there is a greater flow of blood to the wound, they begin to bleed. If the dressing have been applied, the bleeding is first noticed, when it be- comes completely penetrated by the blood. The wound is filled with clotted blood, which renders the discovery of the vessels very difficult. I have treated in this way those cases only where peculiar circumstances afforded the probability of an after- bleeding; as a general practice, however, I do not think it advantageous. [Chelius's opinion on this subject is most certainly correct, the exposure of the surface of the stump should be the exception and not the rule; and if practised, should not be continued more than three or four hours, within which time, with due attention the patient's warmth and circulation will generally have recovered the im- mediate shock of the operation, and the clots in the little vessels will either have been forced out or become so completely fixed as to prevent bleeding. The prac- tice sometimes adopted of covering the whole face of the stump with a thick wad of lint dipped in water, kneading it in, and leaving it on for twelve or fourteen, or even twenty-four hours is bad; as during this time the adhesive matter is poured out, and instead of sticking the surface of the wound together, sticks the lint tightly on, so that it can only be removed with difficulty and with great pain to the patient, and indeed, imperfectly, as the fluffy part of the lint remains tangled in the surface of the stump, the whole of which must therefore be cleared off by suppuration be- fore union can take place. If the surgeon will leave the face of the stump open, and will apply cold water to it, linen which has little or no fluff should be laid lightly over it and not kneaded in, arid frequently replaced before it can stick firmly ; but a light sponge is still better. Some practitioners leave the stump exposed, not merely to guard against after-bleeding, but because they fancy the union will be better if the surface of the wound have first glazed with the adhesive matter poured out. I have not found much advantage gained by employing this mode of pro- ceeding.—j. f. s.] 2696. To promote quick union, after the circular cut, an expulsive bandage is put on, from the upper part of the stump nearly to the end of the sawn off bone ; the edges of the wound are brought together in such close apposition as to form a vertical cleft (1), and in this position are fixed with strips of sticking plaster, passed from one side of the stump to the other, so that the wound is completely covered. Upon the plaster is laid, in the direction of the wound a pledget, and over it a wad of lint, which is fastened with a compress laid crossways over the stump, with some descending turns of a roller, also made to pass over the face of the stump. The tourniquet is applied loosely, so as to compress the artery in case of bleeding. The patient is put to bed, the stump so placed upon a pillow, that the cut surface is a little higher than the nearest joint, and protected (by a cradle) so that it be not pressed by the bed- clothes. On account of the disposition to cold shivering, the patient should be covered up warmly, and take a cup of warm tea, or broth. The application of the sticking plaster over the expulsive bandage, is preferable to that of putting on the plaster first and the bandage after, because the plaster keeps more firm, does not so easily shift, and does not so readily excite erysipelatous in- flammation of the skin (2). I have never noticed, from completely covering up the wound with plaster, any inconvenience from collection of the secretions of the wound ; whilst indeed the edges: of the wound as they swell, protrude irregularly, and often are completely strangulated if a space be left uncovered between two pieces of sticking plaster (3). [(1) With regard to the direction in which the edges of the wound should be brought together, it is questionable whether the vertical one is tbe best, or whether the horizontal one be not preferable; I have tried both again and again, and I am rather more inclined to bring the edges together in a horizontal line, especially in amputations on the lower limb, because without effort and 6imply by the position on its hind surface, on which the stump rests, the soft parts are kept closer together, whilst if the edges be brought together vertically, the resting part of the stump ne- cessarily tends to keep the cut surfaces asunder. It may be objected, that the hori- Vol. in.—55 646 TREATMENT zontal fitting together does not encourage the escape of the fluid from the stump so much as when the edges are brought together vertically, and renders the bagging of matter and sinuses more likely, but this is not the case, and when it happens, depends more commonly on the carelessness with which the after-dressings are made. I have, however, seen many very good stumps made in both ways. (2) Chelius's recommendation of, and reason for, applying a bandage first, and the plaster after are very good, but it must not be supposed a long bandage should be applied ; a covering to the stump a single turn thick, is all that is proper or ne- cessary to bring the soft parts well down to the end of the sawn bone, but more than this heats the stump. I do not agree with him in covering the whole face of the stump with plaster, the less of this the better, provided the object of keeping the skin close upon the face of the stump be effected ; but I have not generally noticed the protrusion of the swelling edges between the gaps of the plaster, unless the plaster have been too tightly applied, which however is often done, and the lips of the wound dragged together as tightly as possible, a proceeding bad, painful and useless, and generally consequent on too little skin having been saved so that the edges will not, if the wound be properly dressed, come together at all. It should be remembered, that the plaster is not to pull the wounded surfaces together, but merely to support them when they are fitted together. I think it therefore better not to fix one end of the strip of plaster on one side, carry it across the face of the stump, drag the edges of the wound together, aad fix the other end on the other side, but whilst an assistant gently brings the edges of the wound together with the finger and thumb of each hand above and below, to place the middle of the plaster strap across it, and then run the ends up along the sides of the stump ; this brings the cut surfaces into better contact, and gives all the support necessary without giving'the patient pain. The first strap should be put on the middle of the stump, and one or two above and below it, a quarter of an inch apart, that whatever fluid oozes out may readily escape, for otherwise, in nine cases out of ten, most cer- tainly quick union of the cut surfaces will be interfered with, if not prevented, and the wound will have to unite by granulation, and not be cured within eight or ten weeks, instead of three or four as commonly, and sometimes in a fortnight as I have not unfrequently seen. As to the protrusion of the swollen edges of the wound, when this happens it is easily controlled either by merely snipping the tight strap a little, near the wound,'or by cutting it across just at the edge of the circular bandage, the plaster with which it is spread being softened by the warmth of the stump rea- dily, in the course of a few minutes allows the strap to move down and the swell- ing disappears. As to the plaster for dressing stumps, provided it be not stimulating, it is not of much consequence whichever is chosen. That commonly used in our Hospital practice is soap plaster with a little resin, to make it more sticky ; but I prefer the soap plaster alone. Tyrrell thought equal parts of soap plaster and compound frankincense plaster made the best dressing. Liston prefers a solution of isinglass in spirits of wine, spread on oiled silk; and Torboch of Sunderland, recommends caoutchouc web, straps of which are said to be capable, from their elasticity, of yielding to the swelling around the wound. The fact is however, that it is matter of little consequence what is used, if it do not irritate, and the surgeon may follow his own fancy. (3) Covering up a stump with pledgets and compress and roller, after the plaster strips are applied, is better left alone, as they heat the stump and encourage suppura- tion. The stump should be kept as cool as possible, and when the patient is in bed, it is a very good practice to lay a thin, cold, wet linen rag lightly over the stump, and repeatedly renew it. The cradle (4) also, should be merely covered with a sheet, though the patient's trunk and other limbs should be sufficiently covered to keep him warm, without making him hot. (4) Cradles are generally made of half circles of stiff iron wire, the ends of which are fixed firmly in two pieces of wood, about eighteen inches or two feet long, as a base, above which the wires rise about twelve or eighteen inches, and support the bed-clothes away from the limb. As the comfort to the patient from the use of this apparatus is great, and it cannot always be obtained in country practice, directly when wanted, it is well to know how to make a substitute or makeshift. A com- mon-sized, flat wash-tub hoop, sawn across, and each half sawn down the middle, AFTER AMPUTATION. 647 furnishes the arches, two, three, or more, as may be needed, and these, having their ends nailed to a lathe on each side, make a very good cradle.—j. f. s.] 2697. The dressing after flap-amputation is to be put on in the same way, excepting that if but one flap be made, it must be laid over the surface of the wound, and its edge fitted closely to the corresponding edge of the skin with sticking plaster and compresses, applied in the direction of the flap, and kept in place by a bandage, of which several turns should pass over the front of the flap. If the amputation be with two flaps, both their surfaces must be brought together, and their edges made to fit completely, and so kept with the dressings already directed. Union of an amputation wound with sutures I consider injurious. [I do not think it of much consequence whether sutures be used or not, in bringing the edges of the wound together; sometimes I use them, sometimes not, as I feel disposed at the time ; but I have never seen any inconvenience arise from their em- ployment, and therefore the surgeon, I think, may use his own discretion, in regard to them.—j. f. s.] 2698. If the amputation wound be to be cured by suppuration and granulation, then, after having put on the expulsive bandage, a pledget spread with mild ointment must be inserted between the edges, straps of plaster laid transversely across, to bring its edges together, and after- wards a compress and bandage, as already mentioned. [I can scarcely imagine a case in which this treatment of a stump can be called for. Occasionally, indeed, it happens that the surface of a stump will become sloughy, and then must unite by granulation; but to make a positive determination to promote union by granulation from the first, can hardly be warranted under any circumstances.—j. f. s.~] 2699. The further treatment of the patient and of the wound must be conducted according to the rules laid down for wounds in general. The accidents which may ensue after amputation are, after-bleeding, violent inflammation, erythism, torpor, gangrene, very copious secretion and bagging of matter, nervous symptoms, protrusion of the bone, sup- puration, and exfoliation of its edge, and ulceration of the soft parts. 2700. The patient should observe the strictest bodily and mental quiet. On the first day he should take merely a little broth and almond milk. An assistant conversant with the use of the tourniquet should be near him; and dressings and every necessary for tying vessels should be in the bed-chamber. If nothing untoward occur, if the general reaction keep up, and if in the stump inflammation ensue within the bounds necessary for the union of the wound, the dressing may be left till fouled by the discharge from the wound, or its renewal on account of ill smell be required. If the discharge be very slight, it often dries up quickly, and the dressings may be left off in the third week, when, after removing the first dressing, I have found the wound completely healed. In taking off the dressings, all its clinging portions should be well softened with lukewarm water, and in doing this, as well as in re-apply- ing the dressing, dragging the ligature-threads should be carefully avoided. Every day, or every other day, or still less frequently, according to the quantity of discharge, should the dressing in this way be replaced. If any parts remain ununited, the clotted blood or the pus must be emptied by gentle pressure. On the seventh or eighth day, it may be attempted to 648 TREATMENT OF remove the ligatures on the small vessels with a gentle pull, and those of the larger ones towards the twelfth and sixteenth. They, however, often remain for a longer time, being held fast by the granulations; the ligature must then be twisted between the fingers, and pulled at the same time (1). I have never seen inconvenience from the ligatures being long retained. The same plan is to be continued till the scarring of the wound be completed; and for some weeks after, the stump must be covered up, and the scar protected from the dragging of the muscles with a bandage. An artificial leg can only be fitted when the scar has become quite tough and the edge of the bone is rounded. The general treatment must depend on the different periods of the cure, and according to the condition of the general health. Proper regulation of the diet, if no particular symptoms occur, renders the use of medicine in most cases superfluous. Benedict's (a) mode of treatment in which the stump is wetted with spirits of wine and bark, and valerian and volatile stimulants given internally at the same time, immediately after the operation, is generally objectionable. [(1) I am not disposed, even when a ligature is retained three or four weeks, to do more than make a gentle pull upon it; for I have known awkward consequences from greater energy. If the ligature, therefore, cannot be got away easily, it is better to fasten its end to a thin piece of whalebone, fixed with sticking plaster on the side and bent over the face of the stump, so as to form a spring; the gentle and constant pull which this makes, generally brings the ligature away in two or three days.— J. F. S.] 27Q1. Should after-bleeding occur, it must be managed as already directed in the treatment of wounds in general {par. 302.) If it be not considerable, but from small vessels immediately after the amputation, the tourniquet must be screwed tight, and cold water poured over the stump for some time. But if the bleeding be greater, if it come from the branches of an artery, or from the trunk itself, then after the tourniquet has been properly tightened, the dressing must be removed, the wound cleared of the clotted blood, and the bleeding vessel tied. If this cannot be done, a sponge dipped in ice-cold water must be applied immediately upon the wound, and pressure also made upon it. Plugs strewed with styptic powders, and bound on with a compressive bandage, may also be here useful (1). If the after-bleeding come on with smart fever, with violent beating of the arteries, and great heat in the stump, it may often be stayed by a free bloodletting, and by continued cold applications to the stump. If the bleeding happen later, and cannot be stanched by either of the above-mentioned means, which is usually the case, because the edges of the wound are for the most part united, or the walls of the arteries, on ac- count of their inflammatory condition, baffle the operation of any ligature, the trunk of the vessel must be cut down upon and tied at some distance from the seat of amputation (2). This practice is simple and safe, as the experience of Dupuytren, Delpech, Zang, and myself have proved. The so-called parenchymatous bleeding, where the blood trickles from the whole surface of the wound as from a sponge, depends either on irri- tation of the wound being kept up by improper or too tight dressing, or (a) Dresdner Zeitschrift fur Natur und Heilkunde, vol. iv. part iii. AFTER-BLEEDING. 649 on the loss of tone of the capillary vessels, or on copious suppuration, in weakly cachectic persons. In the first case, the dressing must be properly adjusted, and every thing which can irritate the wound removed ; in the second, those means must be employed which will raise the tone of the capillary system, as the mineral acids and quinine; cold applications and other styptics must be made to the stump with moderate pressure; and even the actual cautery (3) or tying the trunk of the artery above the bleeding part, resorted to (a). When in ossification or cartilaginous thickening of the arteries, their tying with a broad tape does not secure against after bleeding, nothing remains, if this happen, but smart application of the actual cautery, or tying the principal trunk above the amputation (b). [(1) I do not think the application of a tourniquet to arrest bleeding is advanta- geous, as the blood will find its way into the veins and they will bleed. But I think it best, if the bleeding occur within a few hours after the operation, to open the stump completely, and clear away every particle of clotted blood, and especially, to get it out of all the chinks between the muscles. If this be done, and the stump exposed to the air for an hour or two, it frequently ceases to bleeds If any vessels be found bleeding, they must be at once taken up. I do not like plugs, either simply such, or with the addition of styptics, as they always irritate, and usually are inefficient. (2) It is only in very rare cases that the principal artery should be tied at a distance from the stump, and in general I do not believe it called for. It does not often hap- pen that the bleeding is at first so alarming as to warrant even disturbing the stump; for I have several times seen bleeding occur two or three times during the course of cure, and yet, merely by keeping the patient as low as his condition will permit, and the stump cool, no further mischief ensues. But when the bleeding recurs again and again, and increases in quantity, there is always reason to suspect that there is a cavity within the walls of the stump, into which the bleeding vessel opens, and that the irritation of the clot therein keeps up the bleeding. If this seem pro- bable, the finger, must be gently insinuated between the edges of the wound, till the whole cavity be laid open, and then the entire clot must be cleared away, and if possible, the vessel which hasbled must be found. If it do not then bleed, it had better be left exposed to the air, and often this simple proceeding puts an end to the busi- ness. But should it bleed again, I think, from my own experience, and from the practice of others which I have observed, that it is better to follow a bleeding vessel up the wound, and more especially, if it be near the edge, as then, a probe having been passed into it, the skin may be cut through, and the vessel easily and properly secured. This seems preferable to tying the main trunk, by which the supply of blood necessary for the union of the wound is, in general, either completely cut off, or withheld for some days, and°a sloughing condition is the result. And sometimes even the collateral circulation is so free that tying the principal artery will not stop the bleeding. (3) The use of the actual cautery in after-bleeding especially, if it come on some days subsequent to the operation is excellent practice. Some examples of it I have already mentioned {par. 302, note.)—j. f. s.] 2702. If violent inflammation of the stump occur, it must be reduced to proper bounds, by less tight application of the dressing, by continual cold applications, and by keeping the patient cool. If the inflammation be so great, that it is accompanied with much fever, it will require, ac- cording to the patient's constitution, a strictly antiphlogistic treatment. If there be an erythetic condition, as frequently happens with very sensitive persons, in which the stump is very tender, painfully tense, and burning, the heat much raised, the redness of the edges of the skin and wound very slight, the patient exceedingly restless^ the pulse contracted (a) Chelius, Ueber Nachblutung nacli Amputationen ; in Heidelb. klinisch. Annalen, vol. iii. part iii. p. 337. (&) Chelius, Bericht ueber die Errichtung der chirurgischen Klinik. p. 16.. 55* 650 TREATMENT OF PARTICULAR CONDITIONS and quick, and the countenance anxious, ice-cold water must be applied to the stump, till the heat be diminished, and internally aqua lauro-cerasi, opium with nitre, almond milk, oily mixtures and purgative clysters, must be given, and the patient should take light nourishing food. If the inflammation be accompanied with erythism, leeches and emulsions with camphor and nitre rhust be employed. The cause of death after amputation, is not unfrequently inflammation of the ves- sels; in some cases the veins, in others the arteries are inflamed, often even to the \ heart, and sometimes filled with pus. In such instances, the stump is excessively tender, accompanied with severe shiverings, and very depressing sweats. Local bloodletting and cold applications, with calomel internally, must be here used. 2703. An. insufficient degree of inflammation, or a torpid state, in which the stump is little or not at all painful, the warmth little, even less than natural, the wound flabby and pallid, with a frequent secretion of serous or clammy ichor, the patient very much depressed, and the pulse very small, weak, and quick, requires both a general and local strengthening and exciting mode oftreatment. The stump must be bathed with spi- rituous aromatic remedies, covered with aromatic poultices, mixed with camphor, the dressing moistened with spirit of camphor, or of turpentine, the edges of the wound washed with them, and some even injected into it. 2704. Sloughing requires various treatment according to its cause. {par. 71.) 2705. In copious suppuration, strengthening remedies must be used both internally and externally. If collections of pus" form, its free escape should to the utmost be provided for. With this view a part of the wound not being drawn together with sticking plaster, the pus should be emptied by moderate pressure and injections, and a proper bandage ap- plied. It is rarely necessary to make use of the knife. 2706. Protrusion of the bone is either the result of an improperly per- formed operation, in which too little soft parts are preserved, and these with difficulty drawn over the bone; or copious suppuration and a torpid state come on, in which the muscles and cellular tissues visibly, waste and retract* In the former case, if the muscular surface itself do not pro- ject in a rounded form, nothing can be done but waiting for the exfolia- tion of the bone, to promote which, the marrow must be destroyed, and a bougie dipped in spirits of wine, thrust into its cavity, or the projecting bone must be sawn off. But if the muscular mass do protrude, the superficial muscles must be pressed back, a portion of those attached to the bone removed, and the bone itself sawn off at the necessary height. In the latter case, f have almost invariably observed a fatal result from wasting suppuration. Proper general and local treatment of this torpid state, and when it is removed, and the soft parts have not applied them- selves over the bone, which, however, I have frequently noticed, then the above-mentioned destruction of the marrow in the projecting piece of bone, for the purpose of encouraging its exfoliation, or sawing off the bone, is the only thing which can be done. Pushing forwards the mus- cles and skin, by bandaging, will not in this case prevent the protrusion of the bone; on the contrary, every bandage which makes much pressure, and draws the parts together, renders this state worse, as it increases the consuming suppuration and the wasting absorption. AFTER AMPUTATION. 651 [Protrusion of the bone is one of the most tiresome and vexatious consequences of amputation, as, although it more frequently arises from the circumstances men- tioned by Chelius, yet it occasionally happens, when, although at the time of the operation an ample covering of soft parts had been preserved, after-bleeding comes on some days afterwards, and the wound requiring to be opened completely once or twice, or even more, the soft parts retract, cannot be restored to their first situation, and the bone protrudes. Or sometimes, though there be plenty of soft parts, the dressings may have been too tightly applied, and the soft parts being pressed by it over the bone, slough, even although the mischief be quickly discovered and the pressure removed. Exfoliation, however, is not always the necessary consequence, for I have seen instances in which a bone protruding half an inch has not lost its vitality, but itself granulates, and is also covered by the granulations of the soft parts, and the stump, by careful dressing, heals as well as can be desired, though slowly, and becomes well shaped. When exfoliation does take place, it is often confined to a small portion of, or a mere ring of the end of the bone, and then scar- ring soon follows. But occasionally, though rarely, the bone dies, to some dis- tance, from the face of the stump, and a long portion is thrown off. I hardly, how- ever, recollect an instance in which any material inconvenience even, excepting re- tarding the cure, much less serious symptoms, have arisen in consequence. The wound generally heals, except a small ring of granulations around the bone, and there is little trouble with it. For these reasons, I cannot agree with the violent proceeding of exciting exfolia- tion by destroying the cancellous structure, nor even with the less severe operation of sawing off the end of the protruded bone, as it is impossible to know to what distance the mischief has extended. The case simply requires to be treated as if no bone protruded, by bringing the soft parts forward with gentle rolling; and when the bone is certainly dead and protruded, then to make occasional and gentle attempts to remove it by pulling it with dressing or other forceps.—i. f. s.] 2707. In necrosis of the bone, either only a thin piece of the surface, or a complete ring of it may be dead; in the former case, the necrosed piece is usually removed by absorption ; in the latter, it exfoliates, up to which time the opening leading to the bone, must be kept duly open, mild injections made, and when the separation is completed, it may be pulled out. [Sometimes very enormous pieces of protruding bone exfoliate, being thrown off from a considerable distance beyond the face of the stump. There is in St. Thomas's Museum a piece nine inches long, which came away from the stump of a thigh-bone. I recollect seeing this removed, by merely drawing it away, after several months, with dressing-forceps. The patient had not been further inconvenienced by it, than by his cure being retarded. Such cases are best left to nature; at least some half dozen cases I have seen, were left alone, gave the patient no pain, did not irritate his constitution, and came away in due time. The practice of causing exfoliation, by destroying the medulla, as recommended in the preceding paragraph, cannot be for a moment entertained.—j. f. s.] 2708. Ulceration of the bone or of the soft parts is almost invariably the consequence of some dyscrasic disease, which must be met by proper treatment. Continued superficial ulceration of the soft parts is frequently the consequence of improper dressing, or of its too early removal. A fungous growth from the medullary hole may, according to my experience, in most cases be got rid of by proper compression, and by touching it with lunar caustic ; but when any dyscrasy is in causal relation to it, cor- responding treatment must be employed. [According to my experience, a fungous, growth from the medullary cavity is of no consequence; and generally, the granulations inosculate with those of the soft parts, and there the matter ends, sooner or later, without further notice.—j. f. s.] 2709. As regards the preference of the several modes of proceeding in amputation of the limbs in their continuity, I must, according to my own 652 COMPARISON OF THE SEVERAL MODES. experience, prefer amputation by the circular cut, and that method indeed, in which the skin is divided and drawn back, and at its edge the cut carried vertically through the muscles down to the bone, and then the muscles still remaining attached to the bone cut through still higher, and thus a conical surface of wound formed. The superior advantages ascribed to the flap-operation, to wit, a better covering of the stump with muscle, more speedy union, and therewith a shortening of the cure, over the circular operation just recommended, are groundless. In refe- rence to the first point, Brunninghausen (a) makes a remark which I have also observed, that the covering of the stump with muscle may indeed be effected at the moment of union and for some time, but that after a longer period the bone is merely covered with skin (1). On the other hand, after amputating the thigh with merely saving skin, I have never seen protrusion of the bone. But it must be held: as an objection to flap-operations, that tying the vessels wrhich are obliquely cut through, and often wounded in several places, is more difficult, and the number of vessels to be tied is always greater than with the circular cut, that the wound is larger, and therefore, if union do not take place, wasting sup- puration is to be earlier feared. In other respeets, I do not consider the dispute as to the preference of the circular or the flap-operation of so much consequence as many do, as I am convinced that the successful result depends not merely on the mode of operation, but on the manner of its performance, and specially, on the proper conduct of the after- treatment. The flap-operation, however, must always be considered more suitable when the amputation is-performed at the upper third of the thigh ; when the limb cannot be brought into a proper posture for per- forming the circular cut, and when the destruction of the soft parts is such, that by the flap considerable saving may be effected. I also admit, that in flap-operations, the knife suffers less than in circular operations, a cir- cumstance of importance in Military Surgery, and that, with artificial joints, or fractures of bone requiring amputation, there may be advantage in the flap-operation (b). (1) This observation, as regards both flap and circular amputations, will be found confirmed by every one who examines a stump a sufficient length of time after its complete healing. Although Langenbeck (c) believes the contrary, and that it does not happen in his mode of operating, " in which the stump becomes corpulent, and the bone being completely rounded by absorption, cannot press against the muscles;" I must, however, dispute that this thickening of the stump does occur after every well performed amputation, but depends only on the skin and underlying cellular tissue, and it is a great mistake to refer it to the muscular mass. Langenbeck may probably bear this in mind in his further observations, especially if he have the op- portunity of dissecting a body which has died long after amputation; and I am con- vinced he will find it necessary to retract this statement. That the cure of the wound by agglutination or by suppuration makes a difference, as Blasius supposes, and can only be observed after the cure by quick union of the muscular bolster, I cannot, from my own experience, assent to. (a) Above ciied, p. 58. above cited, in von Graefe und von Wal- (6) Chelius, Bemerkungen iiber die Am- theu's Journal, vol. vii. p. 173.—Langstaff, putationen ; in Heidelb. klin. Annal., vol. i. p. Practical Observations on the healthy and 190.—Beck, Ueber der Vorzuge der Lappen- morbid changes of Stumps; in Med.-Chir. bildung bei der Amputationendiecontinuitat Trans., vol. xvi. p. 128. 1830. der Gliedmassen und die ihr zukommenden (c) Nosologie und Therapie der chirurgi- Operations, etc.. Freiburg, 1819,-^-Klein, schen Krankheiten, vol. iv. p. 313. OF AMPUTATION OF THE LIMBS. 653 Textor (a) has only under certain conditions given preference to the old mode of treatment with the circular, or does he usually prefer the latter 1 [Liston is so great an advocate for flap-operations, to the entire exclusion of the circular, that in his Elements of Surgery, he does not even describe the latter opera- tion, giving as reasons for its omission, that " its inferiority to the method by flaps, is so obvious, and so generally acknowledged, that detail of the different steps of the operation is altogether unnecessary. It is more tedious in performance, more painful to the patient, does not afford so good a covering for the end of the bone, and consequently, not so convenient and useful a support for an artificial limb, and the cure of the wound is protracted. The stump is almost always conical, the end of the bone, is ultimately at least, covered only by integument, and from even very slight pressure, this is apt to ulcerate; exfoliation of the bone follows to a greater or less extent, or unhealthy ulcer of the soft parts continues along with caries of the bones, and partial death of its surface ; and at length it becomes necessary either to perform a second amputation, or to curtail the length of the bone. It may some- times succeed tolerably well when there is but one bone: when there are two, it is altogether inadmissible. In very muscular limbs, when amputation is demanded on account of destruction of the bones and joints, with laceration of the soft parts, as when the patient is not required to have pressure made on the stump, it suits well to make the flaps of integument only, and to cut the muscles short. The advocates for the circular amputation wish it to be believed, (and this is their main argument,) that the exposed surface of the flaps is much greater than that in their favourite method, * * * and have measured, it is said, the area of the one and the other, and given their verdict in favour of the roundabout incision. The accompanying draw- ings (pp. 770,71) from nature, and the corresponding diagrams, speak pretty plainly in favour of the other (the flap) method. In the first there is a cone formed by the cut skin and muscles, with a corresponping hollow and ragged cavity; and the second set shows two smooth nearly triangular surfaces." (pp. 769, 70.) As regards these serious objections to circular operations, I must observe, that in the large hospital with which I am connected, for many years, I scarcely ever wit- nessed the performance of any other than circular amputations, except on the fore- arm, and that the ugly consequences which Liston has detailed, were of great rarity, and not, I believe, attributable to the mode of operation. Of late years, however, more flap-operations have been performed among us than previously and probably, their relative number is now about the same. I have performed about an equal number of each, and the result has been so nearly the same, that in most cases, I hardly think one is to be preferred to the other. The flap-operations are more smart and showy in their performance, but in their result maybe as untoward and unsatis- factory as circular operations have been stated to be. The true eause of the well or ill doing of the case is to be found in the proper or improper dressing of the stomp, not merely immediately after the operation, but up to the complete union of the wound. A stump may be plentifully and superfluously covered with soft parts at the first dressing, yet if not properly managed, or if under peculiar circumstances, the patient have been very restless, and continually moving the limb, the soft parts get displaced, unite awry, and the bone protrudes more or less, or presses so against the soft parts as to cause them to slough. I have seen this occur in flap as well as in circular amputations, and I am convinced that in most cases the fault is in the dressing, and not in the operation, whichever it may be. I believe, with Fergusson (b), that " if rapidity is to^be taken as the test of supe- riority, the flap-operation must be allowed the preference; but in the hands of a good surgeon, the difference of time required for the efficient performance of either, seems of so little consequence, that such a calculation should not be taken into account. * * * I cannot but think, that the same hand which rapidly and safely completes the flap incision, would with almost equal facility, if equally well trained, accom- plish the circular." (pp. 151, 52.) And I also agree with him, that "the compara- tive extent of cut surfaces in the respective operations seems of trifling import; a few inches more or less, provided always that a good stump is left, will never de- termine the issue of an operation." (p. 152.) Fergusson also remarks, in reference to amputation through the calf of the leg and at the shoulder-joint, that " in either of these cases, and whether the operation (a) Neue Chiron, vol. i. p. 483. (b) Above cited. 654 COMPARISON OF THE VARIOUS MODES OF AMPUTATION. has been by flap or by circular wound, the stumps are at last so much alike in certain parts of the body, that it-is occasionally difficult, after the lapse of years, to say whether an amputation has been by one mode or the other; at all events when such distinction can be drawn from the shape of the cicatrices, it is evident that the end of the bone is covered by much the same thickness of soft parts in one instance as in the other. If there has been a full fleshy stump shortly after the operation, all muscular fibre has at last disappeared, and the skin with a substance resembling condensed cellular texture, alone covers the bone." (pp. 153, 54.) The correctness of these observations must be fully admitted, as must also that " this substance, un- doubtedly, gives great protection to the end of the bone, and its presence is absolutely necessary," (p. 154,) not, however, as "a useful support for an artificial limb," as Liston states, for in no case, if an artificial limb be properly adjusted, does it bear on the end of the stump; but if it be made to do so, it may be pretty certainly ex- pected that the part exposed to pressure will ulcerate, and this perhaps be followed by exfoliation of bone. So far as my own experience proves, flap-operations in the continuity of the bone may be performed as successfully as circular operations on every limb but the leg, in which the calf muscles are so bulky, that it is often difficult to get the skin well over them, if they be left, and I do not think the cure is so quick as with the cir- cular. But if a skin flap be made and the muscles cut through directly, I do not think more time is gained than by the circular operation. There is, however, a more serious objection to flap-amputation through the calf, in the greater frequency of after-bleeding; this has occurred to me two or three times, and the number of vessels I have had to take up and the sloughy condition of the whole one, and its tedious union by granulation have almost induced me to determine never to operate on the leg but with the circular. On any other part, 1 believe it is of little consequence which of the two operations is performed. Some surgeons have been accustomed to practise one and some the other mode, and thus having acquired experience, perferred their own method. I have employed both, and shall probably continue to do so, believing, with the ex- ception I have made, that either will answer equally well, provided due attention be paid to the dressing throughout the whole course of the cure, without which all the objections that have been made to either will most certainly be verified.—j. f. s.] 2710. Opinions are divided as to the preference of uniting the ampu- tation wound by quick union, and its cure by suppuration and granulation; the former method has, however, the most supporters, and is, generally, the most proper. As for the rest, many practitioners have exaggerated the evils accompanying the cure by suppuration and granulation. When in this treatment the rules already laid down be observed, the wound not stuffed with lint, and its union not prevented at bottom, but merely at the edges of the skin, according to my experience, the cure proceeds as quickly as with quick union, for the wound after amputation of large limbs never takes place by complete agglutination, in the strict sense of the word. The cure of the wound by suppuration and granulation is specially proper for those cases where the patient has long been subject to ulcers and considerable suppuration, where the quick suppression of the discharge has ill consequences, and translations to the cavities of the body may take place, where issues and other drains are not always able to prevent these evil results (a). Klein, Textor, and others, have denied these statements. This is also Dupuvtren's (6) opinion. He considers that dressing of the ampu- tation wound, by which it is at every point closely united, as injurious, as a com- plete glutination does not follow, and by the collection of the discharge in the bottom of the wound, injurious consequences ensue. He collects all the ligatures into a bundle, which he carries out at one corner of the wound, and if this bundle be not (a) Rust, Ueber die Amputation grosseren Gliedmassen; in his Magazin, vol. vi. p. 337. (b) Above cited, p. 417. RESULTS OF AMPUTATION. 655 sufficiently thick, he increases its size in rare cases, by adding charpie to it. The results of this practice are more favourable than those in which the edges of the wound are completely brought together. Only in amputations required for injuries, and which are at once performed, does he close the wound; in all cases where long continued disease with irritation and suppuration have rendered amputation necessary, the above treatment should be had recourse to, as with complete bringing together, inflammation of internal parts, especially of the belly, may occur. [Among English Surgeons there is no difference of opinion, as to the mode in which union of an amputation wound is to be attempted. In all cases it is en- deavoured and hoped to produce quick union, whether by sticking plaster or by sutures and linen dipped in cold water. The object is to promote adhesive not sup- purative inflammation, as the patient's constitution suffers less from the former than the latter, and the cure is infinitely quicker. The fear of metastasis in consequence of the sudden checking of a drain upon the constitution, by the removal of a limb having a large ulcer upon it, or in a case of compound fracture or other injury where the discharge is profuse, is amongst English surgeons little thought of, as their ex- perience proves it to be, except in very rare cases, without foundation. And the usual rallying of the patient's powers after the amputation of such limb, which at once puts a stop to the drain on the constitution, and relieves the irritation of the nervous system affords no inducement to follow Dupuytren's practice of establishing another after getting rid of one suppurating wound. Experience as to success is the only way by which the correctness of practice can be proved, and the results of English practice in regard to amputation will prove its superiority, if fully carried out, and the necessary and only necessary, dressings for keeping the edges of the wound together, be employed, without swathing in rollers and cross bandages, and even in wollen nightcaps, which in my earlier days I have seen, employed, the only effect of which is that they encourage the suppurative and discourage the ad- hesive process.—j. f. s.] OF RESULTS OF AMPUTATION. This is a subject of the highest consideration to the surgeon as regards his deci- sion on the performance of this operation, and his expectation of the success result- ing therefrom. Benjamin Phillips (a) has given a highly interesting paper on this very serious topic, and the result of his inquiry isj that the mortality after am- putation in France, Germany, America, and England together, is 23T7ff per cent. Dr. Lawrie (b) has also occupied himself with the same important matter, and draws his conclusions from a series of 276 cases of amputations of all kinds, per- formed in the Glasgow Infirmary; from which it appears there were 176 reco- veries, and 100 deaths, or a proportion of deaths to recoveries as 1 to 1*76. Potter (c) about the same time gave to the Medico-Chirurgical Society an ac- count of the amputations performed in University College Hospital, from June 1835 to January. 1841, amounting to 66, with their results, among which there were only 10 deaths, and three of these were among 10 cases of primary amputation for accident. I now give a brief account of 54 amputations which I performed between the years 1835 and 1840 inclusive, at St. Thomas's Hospital; some particulars, of which I shall give more at length, after the description of the several amputa- tions :— («) Observations arising out of the Results don Medical Gazette, vol. xxvii. p. 394. of Amputations in different Countries; in 1841. London Medical Gazette, vol. xxii. p. 457. (c) Results of Amputations at University 1838. College Hospital, London, statistically ar- (fc) On the Results of Amputation; in Lon- ranged; in Medico-Chirurgical Transac- tions, vol. xxiv. p. 155. 1841. 656 AMPUTATION THROUGH THE THIGH. — Lived. Died. Total. Through the Thigh . . . For Accidents, Primary .... ------------, Secondary . . . Scrofulous Diseases of Knee . . 28 14 6 5 1 1 13 4 6 5 5 1 1 4 1 5 1 4 *3 5 2 17 4 Through ihe Leg . . . For Accidents, Primary .... *9 5 . ____« 1,1 Through Upper-Arm . . For Accidents, Primary .... ------------ Secondary . . . 5 1 Through Fore-Arm . . For Accident, Primary .... Other Diseases ....... 1 4 ■- 5 Through Shoulder-Joint . . 1 1 54 41 13 .. 54 The result of these cases is pretty much the same in general at St. Thomas's Hospital, and putting these together with the cases at University College Hospital, it must be evident, that the mortality is a long way below the 50 to'75 per cent. which has been stated by some surgical writers, as the ordinary average of fatal amputations. It will be observed also that the largest mortality is among the cases operated on for accidents, and on the lower extremities. In 7 amputations through the thigh, I lost 6 ; and of 9 through the leg, 3 died. Whilst of 6 primary and 1 secondary amputations in the upper extremity, not a single case was lost. This excess of mortality in operating after accidents, is to be ascribed, when the patients die early, to the conjoined shock of the accident and operation. Besides which the persons admitted into hospitals for such injuries are commonly free livers with broken down constitutions, the like of whom are not unfrequently destroyed by the results of trivial accidents, which run either into erysipelas, or diffuse cellular in- flammation and gangrene.—j. f. s.] [On the Results of Amputation, see the papers of Norris, in the American Journ. of the Med. Sciences, vols. 22 and 26. 1838-40. Hayward, in the same Journal, vol. 26. 1840. Eve, in the Southern Medical and Surgical Journal, vol. 2. 1846. Betton, in the Philadelphia Medical Examiner. Feb., 1846.—g. w. n.] Third Section.—OF AMPUTATION IN CONTINUITY OF THE SEVERAL LIMBS. I.—OF AMPUTATION THROUGH THE THIGH. (Amputatio Femoris, Lat.; Amputation oder Ablosung der Obersehenkels, Germ.; Amputation de la Cuisse, Fr.) 2711. In amputating through the thigh, the circular, or flap cut may be practised, the patient being so placed on a table covered with a mat- tress, that the limbs extend freely beyond its edge, and the trunk be in AMPUTATION THROUGH THE THIGH. 657 a posture between sitting and lying. The sound limb should be sup- ported on a stool and held by one assistant. Another holds the dis- eased limb at the knee-joint in such a way that the leg be bent at an obtuse angle towards the thigh, which itself is a little bent on the groin (1). A third assistant compresses with his fingers or with a com- pressor, the femoral artery on the horizontal branch of the pubes (2). A fourth standing on the outside of the thigh, encircles it with both hands, and draws the skin well up so that there shall-be no folds (3); and a fifth gives the instruments to the operator (4). Compression of the artery by an assistant is preferable to the application of the tourniquet, which can generally be only employed when the amputation is per- formed at the lower third of the thigh ; and the place at which it must then be put on is the upper third of the thigh. [(1) Except when the injury or disease is in the leg, this direction cannot be fol- lowed out: therefore, as, at least with us, the greater number of amputations through the thigh are performed for disease in the knee-joint, and that part is commonly fixed, or its slightest movement so agonizing when there is ulceration of its carti- lages, that any change of its usual posture is not warrantable, the surgeon must be content with his assistant merely keeping the limb steady in any position it can be conveniently held. Occasionally, indeed, the leg can only be held on a pillow, and not till the soft parts have been cut through can the knee be grasped to steady the limb, whilst the bone is sawn. (2) In pressing on the artery at the groin, a very common mistake is to press the vessel down into the thigh, by which it is thrust upon the muscles, and can only be compressed by great exertion on the part of the assistant, and with much unneces- sary pain to the patient. The pressure should always be a little inclined upwards towards the belly, and then the artery can be thrust against the bone and with little effort. It is of great importance, that the assistant who is intrusted with this serious charge, should be well up to his business ; he should be well satisfied of the posi- tion of the vessel, and his capability of commanding it with ease and certainty, and not have to be fumbling about for it during the course of the operation. Having determined this, it is not right that the patient should be subjected to the pressure longer than absolutely needed ; therefore having adjusted his hands, which is best done by placing one thumb on the vessel and the other above it, and grasping the sides of the thigh with both hands, he waits till the operation actually commences, and directly the knife touches the skin firmly presses upon the vessel. (3) This assistant is superfluous, as the operator can himself better retract the skin to the extent he desires, by grasping the thigh with the whole of his left hand. (4) These preliminary directions may by some be considered superfluous; but they are very far from so, as upon the thorough knowledge of the duty of each as- sistant, and his strict attention to that and none other, depends the easy course of the operation. Of this I apprehend no one will doubt, who has had experience in the instruction of students.—j. f. s.] 2712. In performing the circular operation, the operator standing on the outside of the thigh proceeds in the following manner. Carrying his right hand, in which he holds a straight bistoury, under the thigh over to its outer side, he places its edge vertically about a finger's breadth above the knee-cap, but always according to the thickness of the thigh, about three or four inches below the part where the bone is to be sawn through, and carrying it in a circular line around the whole thigh, at once divides the skin and underlying cellular tissue down to the fascia lata. The assistant now again draws back the skin throughout its whole circumference, and the operator makes at the edge thus drawn back some slight cuts, by which the cellular tissue connecting the skin is divided, and the latter can be drawn back two fingers' breadth. If the skin be not divided at one continuous circular cut, the cut upon the under Vol. hi.—56 658 AMPUTATION BY THE CIRCULAR OPERATION. part of the thigh must be first made, and then from the inner end of this the second is carried over the front of the thigh into the outer end of the first. The mere drawing back the skin just mentioned, is better than separating and making flaps of it. If the larger amputating knife be used for this purpose, the cut will be less regular. [Notwithstanding Chelius prefers the circular cut and simple retraction, I think the skin fits better on the face of the stump, if, after that is done, it be divided about an inch vertically on either side, so as to make a sort of flap. The largeness of the knife is not of much consequence; but the best for the performance of the operation is a heavy-backed knife, which cuts more certainly and correctly. I do not see any necessity for changing the knife, as Chelius recommends; one knife ought to be sufficient for the performance of the whole operation.—j. f. s.] 2713. The operator now, sinking on his right knee, carries the large straight amputating knife, which he grasps with his whole right hand, the upper part of the handle resting between the thumb and forefinger, and the rest of it enclosed by the other fingers, beneath the thigh, over to its outside, places its edge vertically at the edge of the retracted skin, and puts the thumb and forefinger of the left hand upon the fore part of the back of the knife (1). He then cuts through.first the muscles on the outer side down to the bone, whilst he bears the knife towards himself and downwards, carrying it round in a circle with a firm stroke, and cuts through the muscles down to the bone. At the moment when the knife reaches the back of the thigh the operator rises and finishes the cut, standing. The assistant who had drawn back the skin, now grasps, with both hands in the muscular cut, in such way that the thumb above and the finger below cross, and draw back the superficial muscles, after which those still remaining attached to the bone are divided higher by a circular cut. A third cut is now made in like manner, by which the periosteum is also divided. By means of a cleft cloth, the uncleft part of which is placed on the hind part of the thigh, and its ends carried on both sides of the bone to the front, the assistant holds back the muscles, and the bone is sawn through where the periosteum has been divided (2). Cutting through the muscles on the outside of the thigh, whilst the knife is drawn towards the operator and downwards has the advantage that the whole edge is made to act, and that it is not necessary to carry the knife round upon the outside of the thigh, to throio it, that is so to change the true position of the hand on the handle of the knife, that the thumb is on the back, and the other fingers on the opposite side of the handle. [(1) I do not see any particular advantage in placing the fingers of the left hand upon the end of the knife blade; at all events in this country, we are accustomed to use the knife with the right hand only. I may lake the opportunity here of hinting to the young operator, that the knife is not to be, as I have occasionally seen it, forcibly jammed through the muscles down to the bone, and the circular cut completed with the smallest possible quantity of the hind part of its blade. Knives are not chisels, as this practice would seem to imply, but they may be compared to very delicate saws ; and as every one knows a saw will only act well, when it moves in a long stroke, just so is it with the knife, of which the cutting part, whether a small portion only, or successive portions of it be used, must be constantly in motion, continually drawn along the part it has to cut, which it will then cut readily, and not violently forced through, as some opera- tor's fancy it very clever to do. (2) I prefer spreading my left hand over the face of the stump and thrusting the soft parts back, to an assistant's aid with a cleft cloth, whilst sawing through the bone.—j. f. s.] 2714. After tying the vessels and clearing the wound from blood, and drying the surrounding parts, a roller must be applied from the upper- most part of the stump, in descending turns, nearly as low as the end of AMPUTATION WITH TWO FLAPS, THROUGH THE THIGH. 659 the bone, for the purpose of drawing the skin and muscles gently to- gether. The wound is now brought together in a vertical direction with strips of sticking plaster of sufficient length, placed across it; upon these a pledget spread with some mild ointment is applied ; a wad of lint and over it a cross bandage, two ends of which come up on the sides, and the others before and behind the thigh, and the ends confined with a circular bandage, a few turns of which are to be passed over the face of the stump. [The roller first and the straps of sticking plaster after, with one strap passing over the whole length of the wound, and a circular strap to confine the ends of the straps, are all that are requisite. No wad of lint, cross bandage, or second roller are required.—j. f. s.] 2715. Amputation through the thigh with two flaps is thus performed. The patient having been placed as for the circular operation, the precau- tions taken against bleeding, and the assistants stationed as before, the operator standing on the outside of the limb, with the fingers and thumb of his left hand grasps the flesh on the outside of the thigh and draws it outwards. With his right hand he now thrusts a long narrow double- edged knife through the front of the thigh vertically down to the bone, and with its point close to the outside of the bone, still thrusts towards the back of the limb till it penetrate behind exactly opposite where it had entered in front. The knife is now carried further downwards, and its edge being turned a little outwards, cuts through the muscles and , skin obliquely. The point of the knife is then placed vertically on the upper (front) angle of the wound, carried down on the inside of the bone to the lower (hind) angle of the wound, and as it descends along the bone with the edge turned from it, a second flap, like the outer one in size and length, is formed. The length of the flap should be, according to the thickness of the limb, that of three or four fingers' breadth. Both flaps are now drawn back with a cleft cloth by an assistant, and the ope- rator, with a circular incision at the bottom of the wound, divides the muscular parts still remaining attached, and cuts through the periosteum v where the hone is to be sawn. The dressing is to be performed in the same manner as after the circular operation. According to Langenbeck's method, the operator should place himself in ampu- tating through the right thigh, on the outside, and when through the left on the in- side of the limb, and first make on the side next him a semicircular cut from the fore to the hind surface of the thigh, through the skin and muscles obliquely down to the bone ; he then carries the knife beneath the limb to the other side, places it at the upper angle of the wound, and draws it, in the same way as in the first cut, to the lower angle of the wound, at which part he must take special care to cut through all the muscles. Both flaps are now to be turned back, and with a circular cut the operator divides all the parts still connected with the bone, at the bottom of the wound. I have stated in reference to this mode of operating (a), that carrying two semicir- cular cuts through a large quantity of muscles as in the thigh, and their exact con- nexion at the angles, would be difficult, and the cuts likely to be unequal; and I find this opinion rather confirmed than disproved by Langenbeck's own observa- tion (b), that "one who speaks from experience, and draws the knife through, instead offirmly pressing it on, the parts will not allow this;" and that he had "amputated after comminuted fractures through thighs which were as fleshy as such limbs could (a) Heidelberger klinische Annalen, vol. i. part ii. (b) Nosologic und Therapie der chirurgischen Krankheiten, vol. iv. p. 312. 660 AMPUTATION THROUGH THE THIGH, WITH SINGLE FLAP. possibly be, and yet the knife, drawn lightly along, flew through down to the bone, and that too at the inner part of the thigh." [Liston (a) makes his flaps before and behind instead of on the sides as directed by ChElius, and I think his the better mode, as the flaps are well kept together by the position of the stump. According to Liston's directions, " the surgeon places himself on the tibial side of the right limb, on the fibular side of the left; lays hold of the soft parts on the anterior aspect of the bone, lifts them from it, enters the point of his knife behind the vena saphena, in operating on the right side, passes it hori- zontally through to the bone, carries it closely over its fore part, and brings out the point on the outward side of the limb as low;as possible; then by a gentle and quick motion of the blade, a round anterior flap is completed. The instrument is again entered on the inner side, a little below the top of the first incision, passed behind the bone, brought out at the wound on the outside, and directed so as to make a pos- terior flap, a very little longer than the former. The anterior flap is merely lifted up after it is formed, but now that both have been made, they are drawn well and forcibly back, whilst the surgeon sweeps the knife round the bone, so as to divide smoothly the muscles by which it is immediately invested. The bone grasped by the left hand, is sawn close to the soft parts, the saw being directed perpendicularly." (p. 384-86.) The same method is also preferred by Syme and Fergusson, the latter of whom justly urges (b) the necessity, before entering the knife in front, of well elevating the skin and other textures, without doing which the front flap will not have sufficient breadth, more specially if the operation be performed towards the lower part of the thigh. The reason, however, why the hind flap should be longer than'the front one is not, as Fergusson considers, because the posterior muscles have greater tendency to retraction than the anterior, but because by the position in which the limb is placed after the amputation, the hind muscles being extended are drawn back from the face of the stump, whilst those in front are relaxed and have therefore no disposition to pull away from the stump.—j. f. s.] 2716. In the amputation through the thigh with a single flap, which is by many preferred to the double flap, because thereby the wound is more completely covered, and the projection of the bone more certainly pre- vented, the flap is made from the outer, (Benedict, Textor, Jaeger,) from the inner side, (Zang, Textor,) or from behind, (Hey,) or before (Benjamin Bell, Le Utras, Foulliay.) A double-edged knife is thrust in one of these directions down to the bone, passed close to it, and thrust out on the opposite side, and then being carried down along the bone, a flap of four or five fingers' breadth is formed. Whilst the assistant holds back this flap, and draws up the skin on the other side, the operator makes a semicircular cut an inch below the part where the knife had been thrust in and out, through the skin, draws it up, and then at the base of the flap divides the muscles with a semicircular cut down to the bone, and through the muscles still remaining attached. I have only employed this method in those cases where there has been unequal destruction of the soft parts on the one or other side, so as to pre- serve a larger portion of the limb, especially in the upper part of the thigh. [Amputation with a flap from behind has been performed by Dr. Little of Sligo County Hospital. Fergusson observes, that "after making such a flap, he should out away a considerable portion of the great sciatic nerve, so that it might not by any chance be brought to lie against the divided surface of the femur." (p. 408.)] [Syme (c) has made the following observations in regard to amputation through the shaft of the thigh-bone :—" The danger immediately attending its performance," says he, "and the inconvenience of its imperfect result, in rendering the stump un- comfortable, have suggested various contrivances and modifications of procedure, (a) Practical Surgery. (6) Above cited, pp. 406, 407. (c) Surgical Cases and Observations; in London and Edinburgh Monthly Journal of Medical Science, vol. v. 1845. RESULTS OF AMPUTATION THROUGH THE THIGH. 661 with the effect, certainly, of restraining the hemorrhage, diminishing the patient's suffering, and promoting union of the wound. But the stern evidence of hospital statistics still shows, that the average frequency of death is- not less than from 50 to 70 per cent., while it cannot be denied that many of the survivors suffer from un- easiness connected with protrusion of the bone. Having from an early period of my practice devoted much attention to the subject of amputation—having seen the cir- cular incision give place to the flap-operation*—and having witnessed the results of these methods, variously modified, in the hands of many surgeons possessing every degree of operative skill, I am at length led to the conclusion, that there is some- thing radically wrong in the principle of the operation. This error I believe to be, dividing the thigh-bone through its shaft instead of the condyles or trochanters. * * * The most frequent occasion for amputation of the thigh is afforded by dis- eases of the knee-joint. Next to this may be ranked compound fractures of the leg and thigh, and then tumours-of the leg and thigh. * * * Dense bone dies more readily than that of a spongy or cancellated structure; and the action of a saw, to say nothing of ruffling the periosteum, must always be apt to cause exfoliation, which, by impeding union of the soft parts, delays union, and opposes its perfect comple- tion, by increasing the scope afforded to contraction of the muscles. It would, how- ever, be a narrow view to suppose that the direct effect of local injury is alone con- cerned in causing death of the bone after amputation, and there can be no doubt that inflammation of the medullary membrane may co-operate, if it does not act exclu- sively, in its production. * * * But if the medullary membrane be liable to inflam- mation, suppuration of its texture, and inflammation of the veins cannotfail to be the fre- quent consequence. * * * But when the bone is divided through the condyles, nothing more than the epiphysis being concerned, the medullary membrane is not at all disturbed, whilst the cancellated structure is not liable to exfoliate, either from proneness to die from injury, or through inflammation of any other texture." (pp. 337-39.) Two cases of scrofulous disease of the knee-joint, in general very favour- able cases for amputation, are given as successful examples of the result of this prac- tice, and upon these the recommendation of amputating through the epiphyses of the thigh-bone is founded. In reading the above paragraph, I was surprised at the dangers and inconveniences resulting from amputation, at the middle or near the middle of the shafts of bones which is most commonly selected for that operation, as detailed by Syme ; and still more at the awful mortality of from 50 to 70 per cent., which " the stern evidence of hospital statistics still shows." And as my recollection of the usual results of am- putation at St. Thomas's Hospital had not led me to consider amputation so formi- dable an operation, either immediately, or in its consequences, except in the case of primary or secondary amputations for accidents, which are always very serious, and most commonly fatal, I referred to my notes of all the amputations I had performed in St. Thomas's Hospital during six years. From these is subjoined an account of twenty-eight amputations through the thigh; five of them were primary, and two secondary; the whole were fatal except one of the latter; the remainder consisted of seventeen cases of scrofulous disease of the knee-joint, of which four died; two of necrosis; one of osteosarcoma,- and one of fungoid disease, all lived. The total of the fatal cases were ten, or 35*7 per cent.,- of the primary, all died ; of the secondary, 1 in 2, or 50 per cent.; of the scrofulous, 4 in 17, or 23*5 per cent. In none of the successful cases did any of the untoward occurrences happen which are mentioned by Syme, though all were amputated through the middle of the bone, excepting that in three cases a very small ring of bone exfoliated, and in which only did protrusion occur, and that only for a time. The results of my colleages* practice in regard to this operation, I am quite sure, correspond with my own, though I cannot report them, but the cases I have given afford a fair estimate of this operation in our Hospital. An account of eighteen amputations through the thigh by Liston has also been given (a), of which for accidents, two were primary, one lived and one died; and two secondary, one lived and one died; eight were for disease of the knee-joint, one fatal; two for painful stump, one for ulcer, one for malignant ulcer, one for erysi- pelas, one for tumour in the ham, all the last six successful. The average of the fatal cases here is 1 in 6, or 16-6 per cent.; in the primary and secondary cases^ 1 ha 2, or 50^>er cent.; and in the scrofulous cases, 1 in 8, or 12 J per cent. (a) Potter, above cited, p. 172-176. 56* 662 REPORT OF AMPUTATIONS THROUGH THE THIGH. From these facts it may be inferred, that the cause of the awful fatality recorded must be sought for elsewhere than in the damage which the dense bone in the mid- dle of the shaft suffers from the saw; and some better grounds must be found for giving up amputation in the middle of the thigh-bone, and resorting to amputation close to its lower or upper end; in the first forming a stump, which, to the great majority of persons subjected to this operation, either cannot be used, or only«with great inconvenience and liability to ulceration; and in the second, forming such a stump as will not permit the use of an artificial leg. How the medullary membrane should be less damaged by sawiug through the ends of bones, where it is certainly in larger quantity than in the middle, where it is in smaller quantity, I confess I cannot understand. Hence, I should be little disposed to follow Syme's recom- mendation, of sawing a little beyond the articular surface. Report of Twenty-eight Amputations through the Thigh,from the Year 1835 to 1840 inclusive. 1835 Ann Quigley, aged 25;admitted June 18. Charles Ayling, aged 47 (flour uorter), admitted Oct. 6. Osteosarcoma of the lower part of the right th,gh- bone, of three years' duration. Simple fracture of right leg with comminution and much bruising.con- sequent on being jam- med between a step and a dray-wheel. On eighth day tlie leg became gan- grenous ; hectic set in and increased. 1836 Edward Clark, aged 14, admitted Aug. 2. William Allen, aged 8, admitted Aug. 23. Disease or Accident. Opera- tion. Ulceration of the cartil- AuS- 19' ages of the right knee joint with-suppuration, and abscess in bursa of m. rectus. Disease commenced,lthree years since, but has not pre vented him walking till the last eight months Sinus leading, into left Sept. 3. knee-joint; no disease of cartilages. A twelve month since sprained the knee; this followed by abscess, which burst a week before his ad mission. July 3. Oct. 21. John Ricksett, aged 23 (sailor) admitted Aug.. 24 Ulceration of the cartil ages of the left knee with suppuration and sinus, leading down to a large abscess in m gastrocnemius, which opened externally by other two sinuses. Dis- ease commenced two years since, after expo- sure to wet and cold at sea. In this case the knee was nearly straight. Sept. 3. Remarks. Dis- charged. With circular cut; five arteries were Sept. 10. tied, and the wound dressed at once with, straps of plaster;, went on well throughout. With circular cut; in dividing the mus- eles a large abscess was cut into be- tween the m. vastus intervus and bi- ceps; free venous bleeding;three arte- ries were tied, but he sunk rapidly. Oct. 21 Seven hours and a half after the operation. With two vertical flaps; three arteries tied, and a fourth an hour after wards. Seven hours after, the flaps werebrought together with straps of plaster. On third day had a smart attack of irritative fever and great heaviness, which subsided about four days after. The wound healed 'kindly at bottom, but one flap slip- ped over the other a little and caused a good deal of trouble. With circular cut; three arteries were tied. The stump dressed at once with, straps of plaster, but did not adhere, became sloughy, a large por tion of skin separated, the bone pro- truded, and the wound healed by granulation; but a ring of bone, about a quarter of an inch deep, ex- foliated, and the stump was very conical ; but after a-few months, as he gained flesh, it ceased entirely to be so. With two horizontal flaps; the knife passed through a large abscess in the bursa of the m, rectus,,in making the front flap; this portion of the ab scess was dissected out. Five arte ries were tied. The femoral vein bled profusely, but ceased on re moving th» tourniquet band. The flaps were brought together with four sutures and straps of, plaster; three of the sutures were removed at fifty hours, and the fourth next day. On the fourth day was attacked with troublesome cough, followed by bleeding from the stump for some hours, which was stayed by the ap plication of a cold wet cloth. On the evening of the fourteenth day he had a smart attack of bilious vomit ing. Nov. 7. Dec. 27. Nov. 29 REPORT OF AMPUTATIONS THROUGH THE THIGH. 663 1837 Samuel Paddon, aged 29 (sailor), admitted March 17, 1836. 1838 James Brooks, aged 25, (paper maker), admitted Feb. 20. Joseph Lee, agec 20 (carter), admit ted May 26. John Millard, aged 42 (sailor), admit- ted May 29. Scrofulous .'disease of knee-joint. Ulceration of cartilages of left knee-joint. Dis- ease commenced five years since, and two years after received a blow on that joint. Compound^ comminute fracture of right thigh bone, with severe lace- ration of muscles by transit of wagon- wheels. May 12. Anchylosis of left knee- joint, with severe pain on slightest touch of the knee. Feb. 3. With two horizontalflaps. May 26. Four hours after accident. With circular cut, and the skin divided upwards on each side. The skin re- tracted, and on the sixteenth day the bone protruded through its upper part. Between three and four months after a thin ring of bone separated, but the wound had not healed when he left the house. With vertical flaps, and through the little trochanter; the femoral artery ■ tied before the completion of the first flap. Flagged very much during the operation, and lost much venous blood; and though brandy was freely given, he became very low and rest less, and with much jactitation, and he sunk rapidly. June 2. Mar. 11. Nov. With vertical flaps; five arteries were tied; lost much blood at the opera tion, and became very faint; the medullary artery bled very fiercely, but was stopped by pressure. As he rallied bleeding began again, and did not cease.till sixteen other ves sels, all of small size and much retracted, had been taken up; the me dullary artery again burst forth, and was again stopped by pressure Another vessel was tied two or three hours after, and the bleeding then ceased. The Haps could not be adjusted as at first; next day he complained of pain in his belly; had tightness at chest, and sighed fre- quently; continued very restless. On the fourth day suppuration com- menced; and he complained of pain on the outer and under part of the stump; a bread poultice was applied. On the fifth day the stump be came more painful, and when pressed much pus was discharged from the upper gap of ihe wound, which was dressed to day, and he became a little the easier; in the evening the pain in his bellyceased. On the sixth day, the pain in- the stump, which had diminished, became very severe, and the outer flap was much inflamed, some way up the thigh ; he was very restless, and had much constitutional excitement. On the following day he was rather better; hut the erysipelatous blush had ex tended upon the buttock. Has hitherto taken laudanum to allay irrita- tion and give rest, which, however, has not been very effective, and beef tea; the latter of which was to-day changed for a mutton chop and a pint of porter. On the eighth day was worse, his tongue coated; pulse very quick and irritable; looks anxious; erysipelatous blush ex- tending to the iliac crest; discharge from wound diminished in quan- tity, and thinner. On the following morning had some hiccough looked wild, though perfectly sensible; and had some mucous rattle in his windpipe, which towards evening increased, and the hiccough con stant. He continued getting lower, and the breathing worse- Brandy was given to keep him up, and the bronchial affection attacked with blister, and afterwards mercurial friction, but without avail; his bowels got out of sorts, but he went lingering on till the evening of the twentieth day. The right pleura was found' covered with coagula ble lymph, and contained four ounces of serum, with flakes, both lungs gorged with sero-pumlent fluid: the bronchial membrane deep red. The mucous membrane of the stomach thickened and mammillated with brownish-red patches; and that of the intestines, small' and large, here and there ulcerated in patches, the stump sloughy. 664 REPORT OF AMPUTATION? THROUGH THE THIGH. 1838 continued. Charles Russell, aged 28 (farm-ser- vant), admitted Dec. 27. Severe laceration of the skin of the right leg and of the m.-gastrocne- mius; consequent on injury by cart-wheel Was much depressed at his admission. 1839 William Wilmott, aged 26 (carman), admitted Nov. 6- 1838. James Arnold,aged 22, admitted Aug 27,1838. Disease or Accident. Dec. 27. Eight hours after accident. Severe contusion of the right leg, consequent on being jammed be- tween a cart-wheel and the curb-stone; follow ed by extensive slough ing of the skin of the back of the leg.and sup- puration beneath the whole remaining skin of the leg and upper part of the thigh; and great depression. Soft anchylosis, ulcera- tion of cartilages and abscess in left knee- joint. Not much af- fected constitutionally by the disease, and very urgent for the opera tion. Eliza Phillips, aged 22, admitted April 23. Opera- tion, Jan. 23. April 18 Soft anchylosis of left knee-joint, with con stant severe pain, spe- cially at night. The disease began at two years of age. The knee bent at a very acute angle, and very tender. May 10. Remarks. With circular cut; four arteries tied; lost much venous blood during the operation, and was much exhaust- ed ; wound brought together with a single strap, and the dressing com- pleted twelve hours after. On the fourth day irritative fever came on, and he became much excited. On the sixth day little union, and free suppuration of the wound, the bone a little protruding. On the eleventh day a little graze on the other leg was observed to be separating, and on the eighteenth about a pint of pus was discharged from beneath it; subsequently suppuration extended beneath the skin of the whole leg. He improved a little, but afterwards sunk again, complaining the day be fore he died, of severeaamin in the chest. On examinatioriUje femoral vein was found filled with pus up .to a valve four inches above its cut end. The bronchi were acutely in- flamed. With circular cut; lost but little blood during the operation; the femoral artery was tied before sawing through the bone, and other three after. The wound was brought to gether vertically with straps of plas ter. He bore the operation very well, but was sick on being put to bed. From this time he gradually improved, and in thirty-three days the wound had healed, and he got up. With two horizontalflaps;the soft parts much consolidated, and the flaps turned back with difficulty. Had little arterial, but much venous, bleeding. Five arteries and the fe- moral vein tied; the latter had bled most pertinaciously. The flaps were at once brought together with ad hesive straps. Next day, much ooz ing having taken place, the flaps were opened, a small vessel found and twisted. In the afternoon he began to vomit; another vessel was lied, and the stump dressed. Third day, vomiting continued, and at night be wandered much; but on the morning of the fourth day he was senseless, continued so for six hours and died. The examination threw no additional light upon the cause of death, which seemed to rest on the constitutional shock from the operation. With circular cut; six arteries and the femoral vein were tied. The edges of the wound were brought together transversely, and fastened with eight pins and twisted suture; a wet rag applied. The pins removed at seventy hours, and union opposite them; dressed with adhesive plaster. In course of a month the wound healed, except a little sinus, where the ligatures had been brought out. Dis- charged. May ' June 12. Died. Jan. 19. Twenty. three days after operation. April 21. Seventy- five hours after operation. REPORT OF AMPUTATIONS THROUGH THE THIGH. 665 1839 continued. Edward Moore, aged 27 (tailor,) admitted June 4. Elizabeth Harley, aged 15, admitted May 28. Disease or Accident. Opera- tion. Abscesses around.but not communicating with the right knee-joint; synovial membrane thickened, soft, and jelly-like, spotted with red; disease began with a fall sixteen months since. Necrosis in head of right shin-bone, and partial destruction of the joint cartilages; at other parts the synovial membrane of the three bones adherent at the corresponding surfaces. June 19. June 30. Remarks. Charles Walder, aged 21 (labourer,) admitted June 5. Ulceration of cartilages. with suppuration in left knee-joint, and ex- ternal Abscesses not communicating ; after a fall two years since. Mary Hutchins, aged 46, admitted Aug. 1. James Lee, agec 28 (ostler,) admit ted May 7. Fungoid tumour on upper part of calf of left leg, abdut the size of an orange. Ulceration of cartilages of right knee, with sin uses; had had amputa- tion performed through the leg seven years since; two years ago fell and bruised his stump; the knee has swollen since, and ab- scesses formed about it during his stay here These have been open- ed, and continued dis charging. July 10. Dis- Died. charged. Aug. 27. Aug. 21. Oct. 2. With two oblique flaps; eleven ligatures applied. Suffered great agony at operation and for an hour after, on which account forty drops of lau- danum given; this quieted him, and the wound was left open for nine hours; two small vessels then tied, and the edges brought together with eight pins and twisted suture; these removed at sixty-eight hours, and the edges found generally united; in their place adhesive straps applied. In about a month the wound healed, and the scar began to draw in With two flaps, oblique, upwards ajidin- Sep1- 1" wards; six arteries tied; the stump left open nine hours till glazed, then all remaining clots removed, and another vessel tied; the edges of the wound brought together, and fas- tened with five pins and the twisted suture; these were removed ^ninety- six hours, and adhesive straps ap- plied. Some weeks after, when the wound had healed, the scar con- traded and drew in, so that there was a cleft appearance of the face of the stump: With two oblique flaps; in making the front one a large abscess was pene- trated, whence much pus escaped; lost much blood,' and ten vessels were tied, and afterwards the sac of the abscess was dissected out; flaps left open, and another vessel taken up; nine hours after the clot remov- ed, another vessel tied, and the flaps brought together with seven pins and twisted sutures; these were re- moved at sixty-nine hours, but not much union. On the next day his bowels were disturbed,and therefore beef tea changed for arrow root and a little meat; and in the evening had pain at the pit of the stomach and nausea. On the eighth day had a shivering fit. Sores formed on the buttocks, hips, sides of the chest, and shoulders about a month after, most of which healed; but early in October psoas abscess appeared in right groin, under which he sunk. With two horizontal flaps; thirteen arte- ries were tied; the femoral was tied two inches above the edge of the flap, but the lower end bled after- wards, and required tying, when the flaps were brought together, ten hours after, with six pins and the twisted suture; these were removed at seventy-two hours, and adhesive straps then put on. She went on without a bad symptom. With circular cut, and cut on each side of the skin; the muscles did not retract in the least; nine arte- ries were tied, and the vein also, as it bled very freely; bleeding recurred during the afternoon, and three more vessels were taken up. Did very well, and the wound healed in twenty-six days. Six weeks after had a severe attack of acute rheu- matism in the right wrist, and afterwards his heart was attacked; he recovered after a month. Oct. 18. Nov. 23 Mar. 17, 1840. 666 REPORT OF AMPUTATIONS THROUGH THE THIGH. Disease or Accident. Operation Remarks Dis- charged. 1839 continued. Sarah Dowles, aged 50, admitted Oct. 1. 1840 Edward Berry aged 13, admitted Dec. 31,1839. William Parker, aged 27 (labourer,) admitted Jan. 22. 1840. Samuel Armstrong aged 16, admitted March 24. Hugh Evans, aged 20 (sailor,) admit ted May 2. Necrosis of right thigh- bone just above the articular surface of condyles, and commu- nicating with sinuses opening above the knee cap and on the inner condyle. Has had dis- ease in the knee-joint for forty years ; but three years ago received a blow on the lower part of the thigh from a boot. Soft anchylosis of right knee-joint and necrosis in head of shin-bone communicating with a sinus. Compound fracture of leg, with simple frac- ture of left thigh, and severe laceration of the skin over, but not com- municating with it; consequent on having been run over by steam-carriage whilst fallen on the rail yes- terday, at 6 p. m. Ulceration of cartilages. with suppuration and adhesive deposit on sy- novial membrane of right knee-joint. Much out of health. Oct. 12. Jan. 18. Jan. 22, Twenty two hours after accident Compound fracture of left left leg, with severe laceration of muscles and simple fracture of same thigh into the joint, consequent on timber falling upon the limb. Had lost much blood. May 2 Three hours and a-half after accident Henry Parker, aged 43 (brewer's servant,) admit- ted June 1. Compound fracture of the left thigh, with lacera- tion from the inner condyle to nearly the pubes, but not much bruising: laceration of right hand and disloca ted metacarpal bone; consequent on transit of a loaded dray-wheel Much depressed on his admission. June 1. Four hours. after accident. With two oblique flaps; twenty-one ves sels were taken up, and the flaps brought together at once. Re- covered, without any untoward symptom. Dec. 24. With two oblique flaps; nine arteries and the femoral vein were tied; nine hours after the face of the flaps was cleansed, other six vessels tied, and the flaps brought together with adhesive plaster. With two vertical flaps; the femoral artery was tied immediately after making the inner flap; afterwards the femoral vein, the deep femoral, and two small arteries. He did not lose two tablespoonfuls of blood; but the operation depressed him considerably; and he sunk rapidly With two horizontal flaps; three arte ries tied, but the medullary artery oozed freely, except when stopped by pressure; the flaps brought toge ther four hours after with adhesive plaster. On the fifteenth day irrita tive fever came on, with much headach, and could not be checked. With two horizontal flaps; four arteries were tied. The wound was sloughy, but had cleared on the eleventh day up to which time he had been tole rably well. On the thirteenth day was attacked suddenly with pleu ritic symptoms, and the sputum slightly tinged with blood; some little cessation of these symptoms occurred, but he sunk. The left pleura contained straw-coloured serum, with flakes of coagulable lymph, and both costal and pulmo- nary surfaces covered with lymph; the lower lobe of left lung infiltrated with pus; its apex consolidated. With twoflaps; immediately on making the first he was violently sick, and I tied the femoral artery before making the second. Some other arteries tied; an hour after opera tion was violently sick, and once after. Four hours after the flaps brought together with three sutures and straps of plaster; vomited again during the night. Twenty hours after the first operation, amputation through the wrist-joint, with a flap from the back of the hand, and five ligatures applied. Sutures in thigh removed after one hundred and eigh- teen hours; the wound sloughy. On seventh day attacked with irritative fever, and on the day following was much purged, and this continued till he sunk. On examination there were found a little lobular pneumo- nia, principally in left lung; some ulceration of mucous membrane of intestines. Mar. 17. REPORT OF AMPUTATIONS THROUGH THE THIGH. 667 1840 continued. Robert Richards, aged 15, admitted June 16. Soft anchylosis of right knee. Disease began nine years since, after a fall. Benjamin Scott, aged 9, admitted June 9. James Vinson, aged 35(farm-ser vant,) admitted Aug. 18. Disease or Accident. Operation. John Pearman, aged 19, admitted Nov. 10. Soft anchylosis of left knee. Disease began five years since, with out known cause. Ulceration of cartilages of right knee-joint, ad hesive deposit on the synovial membrane;the joint full of pus; and the bursa of the m. rec tus full of pus. Origi nated in a blow with shovel nine years since Soft anchylosis of the left knee; abscess above the head of the shin-bone; the remaining joint- cartilages ulcerated. Remarks. Dis- charged. Died. July 25. With horizontal flaps; six arteries tied; the wound brought together with a single strap, and the dressing com- pleted eight hours after. On the fifth day the bone began to protrude, and could not be replaced, but the wound healed, excepting immedi- ately around it, in course of six weeks; and at the end of two mouths a little ring of bone separated; the wound had not completely healed when he left. Sept. 19. With circular cut; four arteries and the femoral vein were tied; the edges of the wound brought together with a single strap, and the dress ing completed seven hours after; went on without a bad symptom. Nov. 14. i With circular cut; the muscles did not retract; and in dividing them, the abscess beneath the tendon of the m. rectus was cut through, but the part on the stump was left; nine arteries were tied; he was much exhausted by the operation, and passed his motions involuntarily the wound was brought together at onte with adhesive straps; the stump was, perfectly healed in three weeks. Dec. 5. With circular cut; six arteries and the femoral vein were tied; the edges of the wound were at once brought together with adhesive scraps, hut three hours after bleed ing recurred, and four more small arteries were tied; the wound was dressed as before; went on very well for a fortnight, and then the stutnp became sloughy, but it clear ed in a few da vs. Oct. 20. Dec. 15. Feb. 2, 1841. Feb. 2, 1841. [Since the last sheet has been worked off, I have met with another paper of Syme's on amputation of the thigh (a) which I had accidentally overlooked, in which, after having advocated since 1823 the superiority of flap-amputations over those by the circular cut, he now states :—" When the flaps are placed together it seems as if nothing could prevent their perfect union so as to effect a speedy cure, and afford a comfortable covering to the bone. In some cases these favourable anticipations are fully realized ; but though a good many days, and even one or two weeks, may elapse without making manifest the disappointment to be experienced, it much more frequently happens that the soft parts, however ample they may have appeared in the first instance, gradually contract and diminish until care is required to keep their edges in apposition over the bone, which sometimes, notwithstanding every pre- caution, at length becomes denuded, and presenting itself to view, whether dead or living, proclaims the unavoidable misery of a sugarloaf stump. This distressing re- sult depends upon the vital contractility of the muscular tissue, which continuing in operation so long as the cut surface is not prevented from yielding by the formation of new adhesions, not only lessens the mass of flesh provided for covering the bone but gradually retracts it together with the superjacent integuments." He thinks that this effect is, among other circumstances, cautpd by amputating through the lower third of the thigh, and has, therefore, for many years recommended amputating through the middle of the thigh in preference, " to prevent the great risk or almost certainty of protrusion to which the bone is exposed when divided at or near its lower third." He then compares the result of amputation with the circular cut through the lower third of the thigh, "which being the thinnest part of the limb, most readily admits of forming a stump composed only of skin," and then directs that "the in- (o) Monthly Journal of Medical Science. Nov., 1846. 668 AMPUTATION THROUGH THE LEG, cision of the skin should be made as near the knee as possible, not in a circular di- rection but so as to form two semilunar edges, which may meet together in a line from side to side without projecting at ihe corners. The fascia should be divided along with the integuments, which are thus more easily retracted—not by dissecting and turning them back, but by steadily drawing them upwards through means of the assistant's hands firmly clasping the limb. This should be done to the extent of at least two inches or more if the thigh is unusually thick. The muscles are then to be divided, &c." (p. 223-25.) These remarks from so able a surgeon as Syme, cannot be passed by without notice, as they might lead the inexperienced to fear operating with flaps in the lower part of the thigh, whilst in reality there is nothing to be dreaded. I have always been accustomed to amputate as low as possible through the thigh, not that the pa- tient might rest on the end of his stump, which is not to be permitted, but simply to give the socket of the artificial leg a better grasp, and I certainly never had a perma- nently protruding bone nor a conical stump. Indeed, so far as I have had opportu- nity of seeing amputations through the thigh, either by the circular cut or by flaps, in London practice, conical stumps are rarities, and I am certain that within the last thirty years, I have not seen half a dozen, and I am convinced that when they do occur, except in the comparatively few cases of sloughing of the stump, even in which they are rare, they are produced, not by the mode of operating, but by want of proper attention to the after-dressing. Indeed I have seen again and again, in olden time, after amputations in which both skin and muscles had been so badly cut, that with all the operator's efforts it was impossible to make the edges of the wound meet by a finger's breadth, and the more he endeavoured, at first, to close the wound and cover up the bone, the more pertinaciously it stuck out, and would not be covered ; yet notwithstanding, I have been again and again surprised at finding towards the end of the treatment, as good a stump made as if the operation had been ever so well performed ; the whole secret of which was that the after-treat- ment was most sedulously attended to. As to " steadily drawing the integuments upwards, not by dissecting and turning them backwards, but through the means of the assistant's hands," I have only to observe that in scrofulous disease of the knee, in most cases, this cannot be done, as the cellular tissue is completely glued up and fixed'with the adhesive deposit in it, and will not move ; neither in case of accidents with large fat thighs, will the cellular tissue yield to any thing like this extent; and it can alone be effected in thin persons of loose fibre, and then only when the disease is of the leg, and not of the knee. With regard to amputating through the epiphyses, which not long since he had warmly inculcated, Syme now says, in this same paper:—"As the soft parts re- quired to form the stump in this situation (amputation at the knee) aTe apt to be so deranged in their texture as to delay, though not prevent recovery, and thus in some measure, counterbalance the advantage of exposing cancellated, instead of dense bone, together with the contents of its medullary cavity, I do not persist in advocating amputation at the knee, now when satisfied that the operation by circular incision, if performed with due care, on proper principles, maybe employed at the lower third of the thigh safely and advantageously (p. 225.) Is not this in fact giving up this much-praised operation?—j. f. s.] II.—OF AMPUTATION THROUGH THE LEG. (Amputatio Cruris, Lat.; Amputation des Unterschenkels, Germ.; Amputation de la Jambe, Fr.) 2717. If the disease which renders amputation through the leg neces- sary, permit, it may be perforrfed above, below, or through the calf; in poor persons, however, the best place is three fingers' breadth below the tubercle of the skin-bone, as with the shortness of the stump, it easily bends back, and the knee becomes the point of support on the artificial limb. The amputation may be performed with the circular cut, or with one«or two flaps. AMPUTATION THROUGH THE LEG, WITH CIRCULAR CUT. 669 2718. The position of the patient is the same as in amputating through the thigh. The tourniquet must be so applied immediately above the knee- cap, that its head may directly compress the popliteal artery (1), and it is intrusted to an assistant. Two other assistants support the leg hori- zontally, and moderately bent at the knee, the one grasping above the foot and the other below the knee, and the latter at the same time draws up the skin moderately tight. The operator should always stand for this operation on the inner side of the leg. [(1) The application of the tourniquet as here directed, is highly objectionable, for it must make voilent pressure upon the popliteal nerve, and cause much un- necessary pain. It should be put on immediately above the middle third of the thigh, and its pad should rest on the femoral artery, where it lies close against the inside of the thigh-bone.—j. f. s.] 2719. In the amputation with the circular cut, the operator makes the skin cut, two or three fingers' breadth, according to the size of the limb) below the part where he will have to saw through the bone, in the same manner with the straight knife, as in amputating through the thigh (1). He then with his left thumb and forefinger takes hold of the edge of the skin, draws it a little up, and with sufficient strokes, separates together the whole fat and cellular tissue, all round from the fascia up to the place where the limb is to be removed ; the detached skin is then turned inside out, and so kept by an assistant. The operator now grasps a straight long amputating knife with his right hand, and sinking down on one knee, carries it beneath the limb over to the inner side, places its edge close to the edge of the retracted skin, and putting the left thumb and forefinger on the fore part of the back of the knife, with proper pressure bears the knife towards himself and downwards, draws it circularly round the limb, rises up, and cuts the muscles through to the bone. He th§n takes a narrow double-edged knife (or catlin) so that the thumb rests on that part of its handle corresponding to the edge, and the fore and middle fingers on that to its back, passes it under the limb, and places its edge, near the junction of the blade with the handle, upon the front of the shin- bone, carries it over the spine, and then with the point of the knife always following the bone, thrusts it from without into the interspace between the bones, down to the handle. He now drops the edge of the knife upon the splint-bone, draw's it, without leaving that bone, up out of the inferos- seal space around the hind surface of the splint-bone, and then thrusts it on the inside through the same space up to the handle, bears it against the shin-bone, and again withdraws it upon that bone. In this way all the parts between the two bones and the periosteum are cut through. Care must be taken in doing this, that the point of the knife be not again pushed through the already divided muscles. The muscles are now held back with a three-headed cleft cloth, of which the uncleft part is placed on the inside of the limb, and held by an assistant, the middle head passed between the two bones, and then laid on the front of the leg, and the inner and outer head so drawn together over the surface of the wound on the inner and outer side, and crossed with the upper part of the middle head, that all the muscles may be covered. Trie assistant now holding the cloth properly drawn together, the operator places his left thumb on the edge of the shin-bone near the place where it is to be cut through, forms first a groove with the saw in the shin-bone, sufficient to determine Vol. hi.—57 670 AMPUTATION THROUGH THE LEG, WITH CIRCULAR CUT. its track, and then drops the saw in such way that the splint-bone may be cut through before the shin-bone. Amputation through the leg in its* lower third was preferred by the surgeons of old; and even up to the present there are some who defend its performance at this place, as on account of the smaller size of the soft parts and of the bones, the ope- ration is less important and dangerous, the wound heals more quickly, and a well- constructed artificial foot can be more easily worn. But this latter point has been directly denied by many surgeons; and on account of the price and of the frequent necessary repairs of such artificial feet, this place of amputation is fit only for the rich, and on account of the smaller wound for old persons. The ordinary mode of amputation with the circular cut is here objectionable, as it is always difficult to dis- sect back-properly the pretty thick and adherent skin, and to turn it up for the pur- pose of cutting through the circular part of the limb. The skin also easily morti- fies, or a badly-covered stump is formed. The formation of a hind flap made, as now to be described, is therefore preferable. Salemi (a) first makes the semicircular cut over the front of the leg and after- wards the flap cut, by piercing the calf with the knife, which answers no purpose at all. Or the circular cut should be made according to Lenoir's (b) method in the fol- lowing way :—"The surgeon standing on the inside of the limb, makes with a nar- row catlin a circular cut through the skin to the fascia, about an inch and a half be- low where the bone is to be sawn through. With the point of .the knife he makes a second cut perpendicular to the former, an inch and a half long, along the inside of the shin-bone near its spine. Then holding the corners of the wound, one after the other, he divides the cellular tissue and its connexion with the fascia and perios- teum and forms with them two flaps, which he turns back at their base. These flaps must be made as thick as possible and not extend below the front third of the leg, as the cellular bridges which connect the skin with the underlying parts, must be divided only behind and on the sides. In this way a sort of ruffle is preserved, cleft in front, and of which the front part alone is turned back on the two sides of the shin-bone, giving to this part of the leg an oval shape, which the knife follows in making the first cut through the muscles. For this purpose the operator places the edo-e of the instrument on the outer edge of the shin-bone, and carries it to the inner edge exactly following the oblique direct of the cutaneous ruffle, cutting through the whole thickness of the superficial layer of muscles at the back of the leg. The assistant now lifts up this muscular layer with the skin covering it, and when they have reached the point where the bones are to be sawn through, the operator makes a second cut, giving it a direction exactly transverse to the axis of the limb, which at once passes through to the deep layer of muscles, and after this he pierces, as usual, the interosseal space and cuts through the periosteum. The retractor is then applied, and both bones sawn through at once and in the same plane. After the vessels are tied, the flesh brought over the bone, and held together by a circular bandage moderately tight around the whole limb, the two lips of the vertical wound in front of the shin-bone are brought together with a suture, and the wound con- verted into the circular amputation wound, which is united in the direction of the antero-posterior diameter of the leg. The patient is then put to bed with his limb laid a little on the outside." . According to Baudens, the amputation may be made even through the ankle-joint, in which case one flap is made from the skin of the instep, and the other from that covering the back of the heel, and the sides of the ankles, and both ankles and the hind part of the shin-bone must be sawn through (c). When the leg is cut off higher than three fingers'-breadth below the tubercle of the shin-bone, the operation must be performed precisely in the way directed above. Disjointing the head of the splint-bone is dangerous on account of the opening of its capsular ligament (d) ; but according to Jaeger and others, this is not to be feared. The operation must not be performed above the tubercle of the shin-bone, as other- wise the insertion of the patellar ligament is cut through, the mucous bag behind it, and even the joint on its sides opened, by which drawing up of the knee-cap and in- to) Pes Inconveniens de 1'Amputation de tomie de Phomme, comprenant la medecine la Jambe au lieu d'election. Paris, 1825. Operatoire, vol. vi. pi. 83.—Froriep, above (b) Archives generates de Medecine. cited. 1840; vol. viii. p. 263. (d) Zang, Operationen, book iv. p. 1 <0. (c) Boubgery, Traite complet de PAna- DRESSING THE STUMP. 671 flammation of the mucous bag and of the joint ensue. Larrey^*) has amputated the leg immediately through the articular head of the shin-bone. [(1) Amputation through the leg should be performed not more than four fingers' breadth below the apex of the knee-cap, in working persons, on whom the Opera- tion is most commonly performed, as the kneeling posture in the bed of the wooden leg is the best and most useful for them; and if the stump be of greater length, its only use is to be in the way and be liable to injury. In persons of easy circum- stances, who can afford to be idle, and are not required to be always a-fopt, a long stump, by amputation a little above the ankle, if possible, which is not always, may be permissible; and they will enjoy the movements of the knee-joint; but for useful purposes, gentle or simple, will find the short stump the best; for it must be re- membered, that in no properly-fitting artificial leg is the weight of the body thrown upon the end of the stump, as some surgeons pretend it ought to be, forgetting if it be, than a sore stump is generally the consequence.—j. f. s.] 2720. Tying the vessels is performed in the usual manner, but is often difficult when the amputation is performed high up, because the vessels are here collected together in a bundle. If the nutritious artery of the shin-bone bleed violently, a little ball of wax must be thrust into its mouth. (1) When the vessels are tied, the ligatures arranged, and the circum- ference of the wound dried, the edges of the skin must be brought to- gether vertically (2), and kept in this position by strips of sticking.plaster, not too tightly applied. A wad of lint and a compress are applied, and lightly fastened with a roller. The position of the stump must be either outstretched or bent at the knee, according as it is intended to preserve the movements of the knee in the application of an artificial legT or to let the maimed person go upon the knee. The after treatment must be directed according to the general rules. Although in the above mentioned mode of amputating through the leg, the skin merely is preserved to cover the stump, I have always found it sufficient, and have never noticed any protrusion of the bone. I have never seen the skin become gan- grenous and burst through by the pressure of the sharp end of the shin-bone, and I therefore consider the recommendation.of sawing it off obliquely, useless and super- fluous (3). [(1) One of the most troublesome circumstances, in regard to tying the vessels in amputating high up through the leg, is when the anterior tibial artery has been divided just after it has passed through the interosseous ligament, and retracts so that it cannot be pulled out and tied, but sometimes bleeds fiercely, especially after the posterior tibial artery has been taken up. It must then be managed, either by carefully cutting through the interosseous ligament till it can be got at and tied, which is the best mode of proceeding; or by passing a needle and thread a little above the divided edge of the ligament on one side of the spot whence the bleeding issues, from before to behind, and then bringing the thread back again from behind forwards, on the other side of the bleeding point, and tying all contained within the loop, which sometimes answers the purpose. Dipping with the tenaculum, and tying all it hooks up, is not advisable, for even if it catch the artery, the ligament is also caught with it, and the ligature cannot be made so tight as to ensure safety from after-bleeding. I have occasionally seen bleeding from the nutritious artery of the shin-bone very tiresome but have never seen it require more than pressure for a little time till a clot is formed. If I could not so succeed, I should rather prefer applying the actual cautery than using a pellet of wax as here recommended. (2) I do not think bringing the edges of the wound together vertically answers so well as horizontally; for in the former case, the skin is not merely unsupported as the stump rests on the pillow, but the pressure tends to make the wound gape] I therefore prefer bringing it together horizontally, by which means the hind par^ (a) Memoires de Chirurgie Militaire, vol. iii. pp. 56, 359. 672 AMPUTATION THROUGH THE LEG, WITH SINGLE FLAP. of the stump is supported by the pillow, and the fore part readily drops to meet it without any stress, and even relieves the tightness of the dressings. (3) I cannot say that I have always had Ohelius's good fortune in regard to the skin covering the sharp end of the shin-bone, as it has happened two or three times in my own practice, and I have occasionally noticed it in the practice of others, that the skin has been pressed on and sloughed. This generally arises from the edges of the wound having been drawn too tightly together, in consequence of the skin saved not being of sufficient length to cover the stump properly, in whatever direction the wound has been brought together; and even when sufficient and the wound has been properly dressed for the first few times, yet occasionally the patient's restlessness and sometimes negligent after-dressing will lead to this tiresome result. I there- fore think it is better to saw off obliquely merely the projecting point of the bone, which prevents any pressure on the skin, except from great carelessness of the me- dical attendant in the dressing.—j. f. s.] 2721. Amputation through the leg with a single flap, is performed in the following way. The precautions against bleeding and the position of the assistants is the same as with the circular cut. The operator stand- ing on the inside of the leg-, places at the part where the bone is to be sawn through, the left thumb on the inner edge of the shin-bone, and the fore and middle finger upon the splint-bone, at the same time pressing the soft parts back to the calf. He now takes in his right hand a narrow double-edged knife, places its point at the part marked by the thumb, on the inner edge of the shin-bone and thrusts it deeply through the skin and muscles, a little obliquely from within outwards and backwards till it rest upon the splint-bone. He then carries the point of the knife close behind this bone, and whilst sinking the handle a little, thrusts it through the outside of the leg, directly opposite the point of its entrance. The knife is now carried far down along the hinder surface of both bones, and then its edge being turned obliquely downwards divides the muscles and the skin. The length of the flap must correspond to the bulk of the leg, it should-always be one-third of its circumference. The skin is now to be divided on the froat of the leg,, half an inch below both corners of the wound by a transverse cut, and separated at the base of the flap, where it is turned upwards, and held baGk by an assistant, who at the same time properly retracts the flaps. For the purpose of dividing whatever still remains attached to the bones, the catlin is carried round at the base of the flap, exactly as in the circular cut. The doubly cleft cloth is now put on, and the sawing of the bones performed as after the circular cut. When the vessels have been properly secured and the wound cleansed, the flap is laid up over the surface of the wound, and brought close to the edge of the skin; in which position it is kept by straps of sticking plaster passing from behind to before, $nd. from side to side. Some turns of a roller are made about the stump, the flap covered with lint, a cross bandage applied over the stump, and its ends fastened with a continua- tion of the circular bandage, some turns of which are carried from be- hind forwards over the stump. In those who have thick calves the knife is not to be thrust close behind the bones, or the flap would be too thick and could not be placed properly upwards. Graefe (a) has invented a peculiar knife for this purpose, of hollowing out the inner surface of the flap. [I have already mentioned (par. 2709 note) the reasons on which I object to flap- (a) Above cited, pi. vii. fig. 4, 5. AMPUTATION THROUGH THE LEG WITH TWO FLAPS. 673 amputations in the leg, and why I think the circular operation should be preferred.— j. f. s.] 2722. Amputation through the leg with twoflaps was first proposed by Le Dran {a), under the notion that two wounded surfaces applied to each other would take on a quicker union: it has been several times perform- ed by Roux (6); Klein (c) also proposed and Weinhold first practised it in Germany. 2723. Amputation through the leg with two flaps is not without diffi- culty, in consequence of the unequal disposition of the soft parts on the two sides of the calf, and of the unequal size and not parallel position of the two bones. No peculiar advantage is obtained from this operation, and it is decidedly less preferable than the circular or than the ordinary flap-cut. It is performed in the following way. The skin is drawn as much as possible inwards, the double-edged narrow knife thrust in close on the in- ner edge of the shin-bone vertically in such direction that the point should. come out on the back of the leg* rather outwards, and as close as possible to the splint-bone. The knife is then carried down along the bones and forms a flap about three fingers' breadth in length. Both corners of the wound are then drawn as far out as possible, the knife placed in the upper corner, and being thrust in at the outer edge of the shin-bone, so that it runs over the outside of the splint-bone into the lower corner of the wound, forms a second, corresponding in length to the first flap. The flaps being now held back by an assistant, the operator cuts through as in the former manner with the eatlin, whatever remains attached to the bones; applies the double cleft cloth and saws through the bones. The dressing is to be performed as in the flap-amputation through the thigh. If the skin be so firmly attached on the front of the shin-bone that it cannot be re- moved as directed, a vertical cut must be made into it upon the shin-bone, and the edges of this cut drawn inwards and outwards* The outer flap may also be first formed by a semi-oval cut, which beginning on the spine of the shin-bone terminates in the middle of the calf, by obliquely pene- trating through the skin and muscles, and separates the above-mentioned flap to its base, whilst all the soft parts are carefully detached from the bones. The inner flap is formed by placing the knife in the upper corner of the wound and thrusting it through the lower, and by drawing the knife down from within outwards. [Liston performs his amputations of the leg with two flaps, " at one of two points according to the circumstances of the patient, the bones being sawn either about mid- way betwixt the knee and ankle, or close to their upper ends. (p. 379.) The ends of the bone when sawn high, are not exposed to pressure, and then there is less oc- casion for a muscular cushion. A sort of anterior flap should be made below the knee, but it is short and thin; the principal covering is obtained from behind, and the incisions must be so contrived that the edges and surfaces shall correspond. A proper fleshy cushion cannot be got lower than the middle of the leg. * * * When the right limb is the subject of operation, the point of the knife having been entered on the outside behind the fibula, is drawn upwards along the posterior border of that bone, with a gentle sawing motion for about a couple of inches, the direction of the incision is then changed, the knife being drawn across the fore part of the limb, in a slightly curved direction, the convexity pointing towards the foot; this incision terminates on the inner side of the limb, and; from this- point the knife is pushed behind the bones and made to emerge near the top of the first incision, the flap is then completed. All this is done smoothly and continuously without once raising the knife from the limb. The interosseous muscular and ligamentous substances are cut; the anterior flap is drawn back, and its cellular connexions slightly divided s (a) Traite des Operations de Chirurgie, p. 568. Paris, 1742. (6) Relation d'un Voyage a. Londres, p. 342. (c) Above cited, p. 5f). 57* 674 AMPUTATION JliST ABOVE THE ANKLE. both are held out of the way by the hands of the assistant, and the separation com- pleted with the saw. By proceeding thus, all risk is avoided of entangling the knife with the bones, or betwixt them. In dealing with the left limb, the proceeding is very similar; the internal incision is not made quite so long; but it should still be practised, for a longitudinal opening of about an inch or more in extent is more easily found in the transfixion, than the mere point at- which the anterior incision is commenced. * * * Amputation close to the joint is performed^ precisely in the same manner: the incisions being made so that the fibula is exposed, and sawn im- mediately below, its head, the tibia close to the tuberosity. * * * The flap-opera- tion may occasionally require to be modified. When muscular plethoric subjects meet with sudden and severe accidents, which demand immediate amputation, the large quantity of muscle which is necessarily left in the flap is liable to suppurate, to retard very much the patient's recovery, and sometimes to produce dangerous con-r sequences. In such cases I have performed the following operation. Supposing the left leg to be injured, with a common amputating knife an interior semilunar in- cision is made through the skin, commencing from the inner side of the tibia, about four fingers' breadth below its superior extremity, and passing over its anterior aspect. A similar semilunar incision is made at the posterior part of the leg, its extremities joining the bones of the previous incision. The integument is then re- flected upwards to a sufficient extent to cover the bones, and the operation finished after the manner of the circular amputation. In fact, this operation differs from the circular only in the form of the incision through the integuments." (p. 379-82.) FuRGUssoNrs mode of operating differs from Liston's in the front flap being shorter. He thus describes it:—"The heel of the instrument (an amputating knife seven inches long) should be laid, on the side of the leg furthest from the surgeon, and the blade should then be drawn across the front, cutting the semilunar flap of skin until its point come opposite to where the edge was first laid on; without raising the in- strument, transfixion should next be made behind the bones, and the rest of the pro- ceedings conducted as in other,instances, (p. 398.) In whatever part of the limb the incisions are made, I. invariably preserve a semilunar flap in front, varying in length, in different cases from half an inch to an inch. I prefer this to the straight incision across the front, recommended by Mr. Hey, believing that the opposite sur- faces will thus fit more acurately to eaeh other."- (p. 400.)] [The ordinary place of amputating thorough, the. leg is, as already mentioned, a little below the knee, but formerly the AMPUTATION JUST ABOVE THE ANKLE was commonly practised, though not laid aside, and very rarely performed ; it how- ever requires some notice. The Dutch surgeon, Solingen, advocated the preservation of as much of the leg as possible, and- that the amputation should be performed immediately above the ankle ; so that an artificial foot with^ narrow steel plates might be screwed on to the sides of the leg, by which he is able to walk as. well as on that which he brought into the world with him. And DioNis;(a) "is of the same opinion, advising the cutting off a leg as low as, possible, provided we find ourselves able to preserve the motion of the knee." (p. 407.) White of. Manchester (b) also took up this practice in 1761, in consequence of having seen in the previous year " a woman who, twenty years before, had her leg taken off a little above the ankle, by advice of her brother, who was a carpenter, and had promised to make her a wooden leg of his own contrivance. The surgeon at first refused to amputate it in this place; but being told if he would not, they would apply to another, he consented to do it con- trary to his .own opinion. The operation was performed by the single incision, and the stump was twelve months in healing." (p. 169.) He mentions nine cases in which he performed* this operation, and was fully satisfied of its superiority over the ordinary mode. In his earlier cases he employed a double flap, butafterwards fol- lowed O'Halloran's (c)mode with a single flap, dressing it and- the face of the (a) Cours d'Operations de Chirurgie. Translation. Edit, of 1710. (6) An Account of a new method of Am (c) A complete Treatise on Gangrene and putatine the lea- a little above the Ankle- Sphacelus, with a new method of Amputa- joint. &c.; in Medical Observations and In- tjoo quiriee, vol/iy, REPORT OF AMPUTATIONS THROUGH THE LEG. 675 stump as separate wounds, and not applying the flap till the twelfth or fourteenth day. Bromfield (a) also, from having noticed (about the year 1740) how well a woman walked who had lost both her feet and about three inches of the lower ends of the bones of the leg by frost-bites, in his lectures, recommended "the operation, when made below the knee, to be as nigh the ankle as the nature of the case would admit of." He was, however, induced to withdraw this recommendation from " some eminent surgeons, assuring him it would be impossible to heel the stump if the am- putation was made very low; for the tendons or their thecse would slough, and most Hkely a second amputation might become necessary." (p. 189.) These absurdities, however, were disproved by some cases in which the operation was performed by a pupil of his, named Wright, first in 1754, which encouraged Bromfield " to put his theory in practice," and "since he received Mr. Wright's papers, he performed the operation many times, and it always succeeded." (p. 192.) How soon Brom- field operated in this way does not appear, but his book was published in 1773, and he there states he had operated " many times." Alanson also followed this method, but applied the flap at once. Hey (b), however, disapprovedjof this prac- tice in consequence of "some oases occurring, in which, from a scrofulous habit, the wound would not heal completely, or remained healed, so that the patient could neither bear the pressure of a socket, nor conveniently use a common wooden leg, (as the length of the leg projecting backwards exposed the stump to frequent in- juries,) I determined to try whether amputation in a more muscular part of the leg would not secure a complete healing, and give the patient an opportunity of resting his knee on the common wooden leg, or using a socket, as he might find most con- venient." (p. 540.) He therefore amputated through the middle of the leg with a single flap from the gastrocnemial muscles, making as Iconsider, a very inconvenient stump. Solingen's operation had thus, in fact, gone completely out ofi use till, about two or three years since, Lawrence performed it suceessfully on a young gentleman who had had his foot crushed. Having become acquainted with this, and having a young woman under my care with scrofulous disease of the foot-which she did not object to part with, though she was indisposed to lose her leg, I determined to prac- tise it, and accordingly on March, 9, 1844,1 amputated three inches above the ankle- joint with a single flap from the back of the leg with as much muscle as I could get upon the knife, but the principal part of the flap consisted of the Achilles' tendon. Four arteries were tied, and the flap fixed with three sutures and a wetoloth applied for twenty hours, when my assistant removed the sutures and applied straps of plaster.- The wound healed very slowly, and had not scarred till after twelve months, when it made a very good stump, and she walks very well on an artificial foot. The course of this case, is tediousness, and the expense of the apparatus satisfy me, though it might be advantageously employed with persons in easy circum- stances, that it is not a fit operation for those who have to labour for their living. In the accompanying report of fourteen amputations below the knee, it will be seen that nine were primary, for accidents, mostly very severe, of which two died, and seven survived ; the other five operations for disease, in two of which a very small portion of the spine of the shin-bone exfoliated, all terminated favourably, so that the deaths on the whole number was only 14-3 p&r cent. Liston's (c) reported cases of amputation through the leg are twenty ; of' these two were primary, and two secondary, for accidents,.all four recovered; one iniwhom primary amputation, and a few days after, secondary, of the other leg, fatal; nine for scrofulous disease of the ankle, two for disease of the foot, one for necrosis, one for osteosarcoma, one for ulcerated stump, all which fourteen recovered; and one for ulcer of the leg, who died. Hence tke deaths on the whole number were lOper cent. These accounts do not confirm Lawrie's (d) statement that " of the more com- mon amputations, that below the knee is least favourable." Neither do they sustain his rule of practice, " in all cases except those of necessity (not a very comprehen- sible expression, j. f. s.) to abandon the operation below the knee." (p. 398.)] (a) Chirurgical Observations and Cases, (c) Potter; in Med. Chir. Trans., above vol. i. cited- (b) Practical Observations on Surgery. (d London Medical Gazette, above cited. Second Edition. 1810. 676 REPORT OF AMPUTATIONS THROUGH THE LEG. Report of Fourteen Amputations through the Leg, from the year 1835 to 1840, inclusive. Accident or Disease. Operated Remarks. Dis- charged. Died. 1836 John Johnson, aged 36 (sailor,) admitted May 4. Severe laceration of the muscles of the foot, and the innerplahtar artery torn,consequent on leg falling on the fluke of an anchor. May 4. six hours after accident. 1837 John James, aged 52, admitted April 11. Ueorge Powell, aged 22 (towing- rope man,) admit- ted June |. Fungous ulcer on heel, of eight mouths. Severe laceration of lower part of left leg, and crushing of the lower end of both its bones, by transit of trait* of steam, earn ages. April 23. June 4. an hour aftes. By circular cut; six arteries tied; in- teguments scanty, and could not be well brought together. Eight hours after, free bleeding, and three more arteries taken up. Except having restless nights, he went on very well till the fourteenth night, when the stump was exceedingly painful; and on the following morning about half an ounce of arterial blood was discharged from the wound, but stopped by little pres sure. Next afternoon the bleeding recurred in a jet to four or six ounces; the bleeding part was there- fore cleared df clot, but no vessel could be found; no more bleeding occurred till early on the twenty second morning, ahd . then to such extent as to render him faint; and this recurred twice in the course of seven hours, but only in small quantity. The wound was laid open and left till night, when as there was no more bleeding it was dressed. On the twenty-third day he bled again; the granulations sur rounding the ligature, by the side of which the blood flowed, were separated, and a little cavity, as large as a nut, found lined with a polished membrane; and at its high- est part an aperture, as large as a pin-hole, through which the blood flowed. This little sac could not be separated from the surrounding parts, a probe was therefore passed into the hole up the artery, and being felt externally, the skin was cut through, and the artery tied an inch above the face of the stump No more bleeding after this, and he went on very well. With single flap of m. gastrocnemii; three arteries tied; much difficulty in securing the anterior tibial. which retracted nearly through the interosseous ligament. The flap brought together with three sutures and straps of plaster; the sutures removed after forty-eight hours. With circular cut; the muscles did not retract at all; three arteries tied did not lose much blood, but was much prostrated by the operation; edges of wound brought together transversely, and three sutures put in; the latter removed at sixty-nine hours. On the ninth day the middle of the wound sloughy; and the skin having been pressed on the spine of the shin-bone, had a small gangre nous spot on it; suffered much from pain in the stump. On the fifteenth day this had cleared off, but the stump was still sloughy, and the ab- sorbents up the thigh had inflamed. In the evening of this day had se vere pain at the pit of the stomach, which subsided after cupping. A small bit of bone exfoliated from the spine of the shin-bone. June 30 June 20 July 11 REPORT OF AMPUTATIONS THROUGH THE LEG. 677 1838 James Trussler, aged 27 (excava tor,) admitted Ja- nuary 12. Thomas Berridge, aged 44 (ware houseman,) ad mitted April 10. Accident or Disease. °Perated Compound fracture of tarsal bones of left foot, with large laceration and wound of ankle- joint, by transit of steam-carriage on rail- road. Strumous abscesses in the ligaments of the tarsus and metatarsus,of seven months' duration. 1839 Barnard Lane, aged 54 (porter,) admitted Jan. 31 George Stilt, aged 33 (labourer,) ad mitted March 2. Compound fracture of the right leg, with protru- sion of the shin-bone; consequent on bag of wool falling upon him. On the second evening there was slight arterial bleeding,which recurred on the slightest move- ment, and continued. The wound became gangrenous on the third day ; and seemed likely to spread,as he was fast hurrying into a typhoid state. Compound fracture of left leg. with severe lacera- tion, and the shin-bone protruding. Great de pression on his admis- sion. Jan.12 Three hours and a half after accident. June 2.. Feb. 2, Midnight. Fifty- seven hours after accident. March 3- Twenty- six hours after accident. Remarks. With single flap ofm. gastrocnemii; six arteries tied; too much muscle and too little skin, therefore part of the former left protruding, and the rest supported with two sutures and plaster; sutures removed at forty two hours, and a small vessel which had continued oozing, was tied On the seventh day the wound was sloughy, and there was slight arte rial bleeding; on the eleventh a sud den gush of arterial blood to the amount of half-a-pint, occurred, which depressed him very much the flap was therefore opened, and a cavity found behind the interos seous ligament, which had been formed by a muscular branch in the flap bleeding into this part when the flap had been brought to its place; it was tied, and the bleeding ceased. On the forty-seventh day a small piece of the end of the spine exfoliated. With circular cut; he suffered exces- sively during the operation, and in sawing through the bone-more than I had ever witnessed. The muscles did not retract; did not lose above two or three ounces of blood; three arteries tied, and edges of wound brought together obliquely with strips of plaster; an hour after very free dripping of blood, and on opening stump five more were taken up; the stump left open, and six hours after three more, after which the wound was brought together with strips of plaster. With the circular cut; very free bleed- ing at the operation; three arteries and the posterior tibial vein tied; the wound brought together hori zon tally with straps of plaster. He improved at first after the opera tion; but on the evening of the fourth day after the operation, be came suddenly and violently deliri ous. On thejf/tA he began to vomit frequently, and the stump was sloughy; next day he was better On the eighth day was attackedwith trismus, and could scarcely swal- low even his spittle; the muscles be- tween the lower jaw and hyoid bone were violently contracted, and the latter forcibly pulled up between the branches of the former. On the ninth had some severe spasms about the throat like those of a hy drophobir. patient when about to drink. On the tenth day became ge- nerally tetanic, in which state he continued till death. With circular cut; lost very little blood; two arteries only tied; wound brought together horizontally, with a single strap of plaster; the dress ing completed four hours after with plaster. Fart of the stripped-up Bkin had been used for the covering, but this sloughed, as did afterwards the whole of the skin saved;-the wound healed kindly by granula- tion. Dis charged. May 29 Sept. 18 May 29 Died. Feb. 12. Ten days after operation. 678 REPORT OF AMPUTATIONS THROUGH THE LEG, Accident or Disease. Operated on. Remarks. Dis- charged Died. 1839 continued. John Cartwright aged 52 (labourer) admitted May 28. Sarah Hattam, aged 57, admitted Sept. 10. Ulceration of cartilages of the tarsal and meta tarsal joints of the left foot; consequent on sprain fifteen months since. Dry gangrene of toes of right foot. June 15. Nov. 26. Jesse Gooderich, aged 15£, admit- ted Sept. 20. 1840 James Neal, aged 12, admitted Jan 18. Severe laceration of the skin and muscles of the left foot and ankle; consequent on wheel of rail-carriage passing over it. Severe laceration of the skin and muscles of the upper part of the calf of the leg and fracture of the fibula; consequent on being caught in a tobacco-cutting engine. Sept. 20. Seven hoursafter accident Jan. 18. Three hours and a-half after accident William ShearingjUlceration of the leg and aged 33 (actor,) admitted Feb. 4. parti al pes equinus after compound fracture of the right leg four years since. With circular cut; five arteries tied, and two more two hours afterwards. Ten hours after the operation the wound was brought together hori zontaily, and fixed with four pins and twisted suture; these were re moved after fifty-eight hours and a half; surface of stump became sloughy. With circular cut; four arteries tied at the operation, and four more seven hours after, and in another hour a ninth, and then the stump dressed with plaster. Free oozing of bloody serum for several days On the tenth day the greater part of the skin covering the face of the stump was sloughy; ten days after the line of demarcation became dis- tinct, and healthy pus secreted. The wound afterwards granulated kindly as her health improved, but had not healed when she left. With circular cut; six arteries tied ; wound brought together horizon tally with straps of plaster; no irri tative fever. With flap from inside of leg; removed the broken fibula at its joint; seven arteries and the posterior tibial vein tied, and soon after another artery was tied; a single strap was put on, and the wound dressed properly eight hours after. On fifteenth day some bleeding, from one of the liga- tures having been dragged accident- ally; on the next day bled again, from a little superficial vein, and at each of the two following dressings. One of the ligatures remaining fast, a whalebone spring was put on it on the thirty-ninth day; it came away three days after. On the fifty-first day some swelling upon the m. vastus internus, which he says has been coming on a few days, it fluctuated; was left alone, and filled the whole of the front sheath of the fascia lata. On the hundredth and second day this was punctured, and a pint and a-half of pus discharged. The abscess filled again, pointed at the great trochan ter twelve days after, and two pints of pus discharged by puncture. A fortnight after, when the discharge of pus had nearly ceased, the upper part of the thigh was attacked with erysipelas, which spread over the loins and back, on the left side of the belly, and did not subside for a week; after this he slowly recovered. With flap of the m. gastrocnemii; four arteries tied, and bleeding still con linuing three hours after, five more were tied, and the face of the stump left open. Eight hours from the operation three more arteries were lied, and the wound brought toge ther with straps of plaster. Went on well, but slowly; excepting that one ligature would not come away and, therefore, on the forty seventh day, a whalebone spring was put on; but two days after the ligature broke off short and remained. Aug. 27 Feb. 4. Nov. 13 June 16. AMPUTATIONS THROUGH THE UPPER-ARM. 679 1840 continued. Philip Jas. Punch, aged 14, admitted May 23. Accident or Disease. Michael Daly, aged 38, admitted May 26. Compound fracture of the right tarsal-bones and inner ankle, with great laceration of the soft parts, and the posterior tibial artery and^nerve torn through at ankle; consequent on being caught between the spring and wheel of a locomotive carriage, Compound fracture of left leg; the shin-bone com- minuted; skincutclean, but the muscles much lacerated; consequent on locomotive carriage wheel passing over. Operated on. Remarks. May 23. With circular cut, and side cuts; two Four arteries tied; and the wound brought hours together at once with straps of plas after ter horizontally, accident. May 26. With circular cut and side cuts; six Four arteries tied; venous bleeding great; hours wound brought together at once and a-half with straps of plaster. An hour after after, bleeding came on, and two accident. more arteries were tied; but it con tinued, and seven hours after seven other arteries were tied. Fivehours after, the bleeding continued to the amount of twelve ounces, and three more arteries were tied. The stump was then left open, and not. dressed with plaster till twenty-six\ hours after the operation. On the fourth day th? edge of the ski n was sloughy, and the whole of the face of the stump became so afterwards; on the following day irritative fever set in. Dis- charged. Died. July 18, June 7. Twelve days after operation. III.—OF AMPUTATION THROUGH THE UPPER-ARM. (Amputatio Brachii, Lat. ; Amputation des Oberarmes, Germ.; Amputation du Bras, Fr.) 2724. Amputation through the upper-arm may be performed with the circular cut or with flaps, and both are performed in the same way as in the thigh. The patient is placed on a chair, and the upper-arm separated from the trunk, so as to form a right angle. If the amputation be per- formed in the lower third, or in the middle of the arm, the brachial artery must be compressed by an assistant in its upper third. If the amputation be performed in the upper third, the subclavian artery must be compressed above the clavicle against the first rib. [In amputating through the upper arm it is always advisable to make the stump as long as possible; as thereby an artificial arm is better fixed, and is rendered more useful. In the accompanying report five of the amputations through the upper arm were primary, and one secondary for accidents; all recovered, but in two of them a narrow ring of bone exfoliated. Liston's amputations through this limb are seven, of which one was primary for accident and lived ; four for scrofulous disease of elbow, of whom two died; one for disease of elbow consequent on burn, and one for senile gangrene»both of whom re- covered. Thus, the deaths on the whole number were 28.5 per cent.] 680 REPORT OF AMPUTATIONS THROUGH THE UPPER ARM. Report of Six Amputations through the Upper Arm, from the Year 1835 to 1840, inclusive. Accident or Disease. 1835 Edward Walpole, Gangrene of fore- and up aged 31, (wagon- er,) admitted Feb. 9. 1836 James Cook, aged 8£, admitted July 25. per-arm, consequent on a blow from a box ten days since on the former. Was fast sinking at the time of operation, consequence of irritative fever and diarrhaa, MurtaghDowning aged 20(machine- boy,) admitted Sept. 3. 1838 Daniel Edwards, aged 50 (excava tor,) admitted Fe bruary 22. William Beevers, aged 27 (stoker,) admitted Feb. 23 John Hall, aged 14, admitted Feb. 17, Severe laceration of skin and muscles around the elbow, consequent on re ceiving the discharge,of a carronade close by him. Said not to have lost much blood. The radius was fractured, but the brachial artery and el bow-joint were unin- jured. Compound fracture of the left olecranon, with wound into joint, and extensive laceration of the skin and muscles; consequent on having been caught by the drum- strap of a printing-ma- chine. Severe laceration of skin of the back of the hand, and of adducting mus cles of the thumb, con sequent on earth-slip falling on him. A fort- night after, great suppu ration, irritative fever, and erysipelas came on, which extended above the elbow; sloughing of cellular tissue of fore- arm. Troubled much with cough, and bowels very lax; and he became much exhausted. Bleed ing to the amount of two ounces from an artery near the wrist. Extensive laceration of the skin of the right forearm, with some laceration of muscles, and the skin separated some distance above the elbow, conse- quent ou being jammed between steam-engine shaft and deck timbers Compound fracture of the right upper and fore-arm, with severe laceration of soft parts, consequent on cart wheel having passed over the arm whilst fal len on a rail road. Operated Dis- charged. Feb. 17. With circular cut through insertion ofm. coroco- April 19. Eighteen brachialis; the parts All so glued together days after that the skin could not be retracted, but was accident, dissected up. A portion of sloughy skin was included in the cut, which also divided a sinus close to the bone. Four arteries were tied: wound brought together with straps of plaster. Felt better next day, but on third day had hiccough, with cold sweats; these, however, soon subsided. On fourth day the bone protruded; on the following day was attacked with erysipelas of the ears and face; on the eighth day was delirious, but better on the tenth, and then steadily im- proved. On the thirty-eighth day a ring of bone was easily removed, and soon after the bone was covered with granulations, which skinned slowly, and the wound had not healed when he left. July 25. With circular cut, just above insertion of m. Sept. 17. Two deltoides; four arteries tied; the brachial hours exceedingly small; the wound was dressed after With straps of plaster four hours after; went accident. on very well, and in a month the wound healed, except opposite an edge of bone which seemed likely to exfoliate, but it did not, and the bone was completely cover ed before he left. Sept. 3. Two hours after accident. April 17, Fifty-four days after accident. Feb. 23. Nine hours after accident. Feb. 17. Nine hours after accident. With circular cut; through insertion of m. del- Nov 1. toides, but some of the detached skin was used to cover the slump, as there was not enough without. Three arteries were tied, and the wound brought together with three sutures and straps of plaster; sutures re- moved at seventy-two hours. About the tenth day there was a little sloughing at the edge of the detached skin With circular cut, and two side cuts; five arte- June5. ries tied; very little bloo lost;, three hours after the wound was brought together with straps of plaster; went onwel) for a fortnight then flagged, but soon rallied. Withaflap of the separated skin, and a circu- lar cut through the muscles, about middle of arm; the muscles did not retract at all; four arteries tied; wound brought together with two sutures; and six hours after, dressing, completed with strips of plaster; sutures removed it forty-five hours; the skin sloughed, and the stump healed by granula tion. With circular cut; in making which, the mus- cles had been separated beneath from the skin, burst out, and became tightly girt by it; three arteries were tied; a single strap put on, and the dressing completed with straps of plaster twelve hours after. On Ihe fourth day part of the skin covering the stump was sloughy, and afterwards sepa- rated; the bone protruded, and about two months after the operation a narrow ring of bone was removed. April 10. April 28. [ 681 ] IV.—OF AMPUTATION THROUGH THE FORErARM. (Amputatio Antebrachii, Lat.; Amputation des Vorderarmes, Germ.; Amputation de VAvant-Bras, Fr.) 2725. The fore-arm may be amputated with the circular cut, with two or with one flap. The patient either sits on a chair or lies near the edge of his bed. The brachial artery is compressed by an assistant, or with a tourniquet, in the middle of the upper-arm ; the fore-arm held by one assistant at its lower, by another at its upper part horizontally, and in a position between pronation and supination ; the latter assistant at the same time drawing back the skin moderately tight. The operator places him- self on the outer side for the right, and on the inner side for the left arm. 2726. The practice with the circular cut is precisely the same as that for amputation through the leg. Both bones must be sawn through at once. Amputation with a single flap is performed with the flap on the inner (front) surface of the arm. At the part where the bone is to be sawn through, the narrow double-edged knife is to be placed vertically upon the radius, and whilst with the fingers of the left hand the skin and mus- cles are drawn inwards (forwards,) the knife is passed vertically on the inside (front) of the bones, so that its point may project on the ulnar side, directly opposite the point of entrance; it is then carried down along both bones, and with its edge inclined outwards (forwards) cuts out. The length of the flap must depend on the thickness of the fore-arm (par. 2721.) Upon the back of the fore-arm and a finger's breadth from the two angles of the wound, the skin is to be cut through with a transverse cut, dissected back to the angles, and the operation completed as in the flap-amputation of the leg. If two flaps be made, the first is to be formed as just mentioned, the knife is then placed in the upper angle of the cut, carried on the outer (hind) surface of the bones into the lower angle and then forms a second flap corresponding to the first in length. Both are then held back, so that whatever remains attached to the bones, and the interosseous membrane, may be divided as in amputation of the leg. The doubly cleft cloth is then applied and the bones sawn through. In amputating through the fore-arm there should be, as through the leg, sufficient skin to cover the ends of the bones completely. After the circular cut, three or four ligatures are usually sufficient for tying the vessels, and of these, the interosseal artery requires the pressure on the brachial artery to be relieved, so that its mouth may be seen. In single flap-amputation tying the vessels is more tiresome, and with two flaps even eleven arteries may be tied (a). [Not unfrequently in flap-amputations through the fore-arm, the muscles retract less than the skin after division, and consequently the tendons are often left project- ing and cannot be properly got in, on closing the wound. When this happens, as it does most usually in the lower third of the fore-arm they should be shortened about an inch with the knife. It must also be recollected, that the ends of the radial and ulnar arteries are to be looked for at the edge of the front flap, and sometimes the muscles will have retracted from them so much that they actually stand out, and for the moment may be mistaken for little tendons. (a) Klein, above cited, p. 46. Vol. hi.—58 682 REPORT OF AMPUTATIONS THROUGH THE FORE-ARM. Amputation through the fore-arm should always be made as near the wrist a9 pos- sible, so that the socket of any kind of artificial hand may have better hold. The amputations I have performed through the fore-arm were only five ; of these one was primary for accident, and four for scrofulous and other diseases. I have not here included another amputation through the fore-arm for accident, as the patient, Henry Parker, has been already mentioned (p. 666) among the fatal cases of ampu- tation through the thigh. This second operation was performed twenty-six hours after the accident. Liston's cases were six, of which four were for scrofulous disease ; one for ence- phaloid disease of the hand; one for painful stump, all of which recovered.] Report of Five Amputations through the Fore-Arm from the year 1835 to 1840 inclusive. 1831 Samuel Winter, aged 68 (labourer) admitted June 20. 1838 Thomas Voung, aged 42 (water- man.) admitted March 24. 1839 Henry Brewer, _ aged 36, admitted Sept. 10. 1840 Benjamin Neal, aged 15|, admit- ted Jan. 17. William Dodds, aged 35, (tailor,) admitted May 19. Accident or Disease. Scrofulous disease of right wrist-joint, of eighteen months. Contraction of the anus cles pf the hand and fingers after diffuse cellular inflammation, nine months since. Scrofulous ulcers on right hand, with stiff fingers. Disease first showed it- Self twenty-ene months since. Compound fracture of the first three metacarpal bones, and severe lace- ration of the skin and muscles. Medullar sarcoma of right raMfut; first com menced since. four months Operated July 21. March 31 Oct. 10. Jan. 18. Twenty- four hours after accident July 18. Remarks. With two flaps just above m. pronator qaadratus; three arteries were tied and the flaps brought together with three sutures and strips of plaster. In the evening felt severe smarting in the stump; became sickish, and constantly retching; about four hours after vomited profusely, and the smarting subsided. Sutures re moved at forty-four hours. With twoflaps; two arteries tied, flaps brought together with four sutures and straps of plaster; sutures re- moved at forty-six hours. Attacked with vomiting on third day, but not continued. On fourth day stump attacked with erysipelas, which subsided after two days. On twenty- sixth day a. whalebone spring ap- plied to the remaining ligature which would not come off, and after wearing for ten days it was pulled out. With twoflaps; five arteries were tied, and the wound brought together with straps of plaster; but free ooz ing continuing.it was opened again, and two more arteries were tied; the dressing left for a few hours. With twoflaps; four arteries tied; the flaps brought together with straps of plaster five hours after. With twoflaps; five arteries were tied; the venons bleeding very free, as the veins were very bulky. Flaps brought together with plaster three hours after. Dis- charged. Sept. 2. MayS- March S- V—AMPUTATION THROUGH THE METATARSAL AND META- CARPAL BONES. (Amputatio Metatarsi et Metacarpi, Lat.; Amputation der Mittelfuss-und Mittelhand- knochen, Germ.; Amputation des Os du Metatarse et du Metacarpe, Fr.) 2727. Amputation through the metatarsal bones is differently perform- ed, according as the metatarsal bone of the great or little toe, or of those between them are to be removed; and according as the soft parts are more or less destroyed. AMPUTATION THROUGH THE METATARSAL BONES. 683 The tourniquet should be applied above the knee and intrusted to one assistant; another holds the foot, and a third draws the toes asunder. The patient is to be placed as jn amputation through the leg. 2728. Amputation through the metatarsal bone of the great toe is per- formed in different ways, according as the condition of the soft parts admits the formation of an inner, upper, or under flap. 2729. If the flap be formed from the sole, the operator, when the left foot is operated on, grasps the great toe, and draws it inwards, whilst an assistant draws the next toe outwards; but if the right foot be operated on, the operator grasps the second toe and draws it outwards whilst an assistant draws the great toe inwards. The knife is now carried between the toes vertically, along the outside of the great metatarsal bone, to the part where it is to be sawn through. The knife is next placed on the inner side of the bone, at like height with the angle of the first cut, near the lower edge of the bone, and makes, as it is drawTn out along the under surface of the metacarpal bone, to its junction with the toe, a cut which separates the soft parts. The two cuts are now united by a transverse one running over the dorsal surface of trie metatarsal bone about two lines below the angles of the two wounds; and a second transverse cut on the sole connects the front angles of both side cuts. The two flaps thus bounded are separated from the bone as far as the upper angle of the side cut, turned back and held by an assistant, who at the same time draws back the skin on the dorsal surface of the foot as far as possible, whilst the operator pulling the toe well inwards, away from the others, carries a narrow knife upon the back of the foot into the angle of the outer cut between the two bones, guides its edge towards the great metatarsal bone, cuts through the tendon, which he fixes with the thumb of his left hand, and carries the knife at the edge of the retracted skin, over the dorsal surface of the foot inwards, to cut through every thing remaining attached to the bone. The knife is then passed from the sole, between the two bones, and carried along the edge of the retracted flap upon the under surface of the bone inwards. All the soft parts having been thus divided, are held back by a cleft cloth, and a thin splint being passed between the two metatarsal bones and held by an assistant, the bone is sawn through with a bow saw at the edge of the retracted skin. The bleeding is stanched either by Jying the vessels or by cold water, and after the wound has been properly cleansed, the flap is laid up over the bone in such wray that its front edge is brought in close to the edge of the skin on the dorsal surface of the foot, and here fixed by several straps of sticking plaster applied from the sole. The edges of the wound on the second metatarsal bone are also brought together with sticking plaster. Cutting through the tendon is often very troublesome; it is best done by thrusting the point of the knife between it and the bone, with the edge toward the tendon, up to the broad part of the blade. 2730. When the condition of the soft parts requires the flap to be made on the inner side of the metatarsal bone of the great toe, the skin there must be drawn inwards with the thumb and fore-finger of the left hand, a straight knife thrust in vertically on the outer edge of the bone, about a finger's breadth from its tarsal junction, its point carried on the inside of the bone to the sole, and pushed through. The knife is then carried 684 AMPUTATION THROUGH THE METATARSAL BONES. close along the bone, on its inner edge, to its junction with the great toe, and there cuts out obliquely. A cut lengthwise between the great and next metatarsal bone is now made in the same manner as in the former case, and continued to like height with the flap-cut; the flap is then held back, the knife placed in the upper angle of the longitudinal cut between the two bones, and carried over the back of the metatarsal bone to the angle of the flap-cut. The knife is next passed in below, between the bones, and carried round semicircularly, in the sole, to the lower angle of the flap-wound, and thus the division of all the soft parts still remain- ing attached to the bone completed. The cleft cloth having been now applied, the bone is sawn through in the same way as directed in the former case, and after the bleeding has been stanched, the flap is laid down over the bone on the corresponding wound-surface of the second metatarsal bone, confined with plaster, and dressed as already mentioned. Where the condition of the bone permits, it is best sawn through obliquely from within outwards, so that the cut surface may correspond with the inner edge of the foot, by which the projection of the stump of the bone is prevented. In doing this, the longitudinal cut between the two metatarsal bones should end half an inch be- low the beginning of the flap cut, and the upper and lower cuts through the skin, tendons, and periosteum, connecting the two longitudinal cuts, carried obliquely from the one to the other, and the bone sawn through in a corresponding direction (a). 2731. When it is requisite to make the flap on the dorsal surface of the metatarsal bone of the great toe, a cut is made lengthwise between the first and second metatarsal bones up to the part where the bone is to be sawn through ; next a longitudinal cut along the inner edge of the great metatarsal bone, and both connected by a transverse cut behind the head of the bone. The flap thus bounded, is separated from the side cuts, drawn back by an assistant, and, as in the formation of the flap on the sole, every thing covering the bone is divided by two semicircular cuts, at the edge of the retracted flap. The sawing through the bone and the dressing are to be as already directed. Amputation of the metatarsal bone of the little toe is precisely similar to that of the great toe. [These amputations of the great toe are exceedingly neat and well-looking opera- tions, and if the metatarsal bone be sawn obliquely as Chelius directs, but little de- formity ensues. Unfortunately, however, it often happens, especially in working people, that the flexor muscles of the other toes are incapable of sustaining the longi- tudinal arch of the foot, the great support of which is lost by the removal of the ball of the great toe, and the absence of firm attachment for the great flexor tendon of that toe, in consequence of which the whole inner edge of the foot comes to the ground, and the weight of the body upon the flap. The irritation to which its scar is neces- sarily subject, often also causes it to ulcerate, and a very troublesome and inconve- nient sore, which completely lames the patient, is produced. I have seen this occur two or three times; for although the patient had left the surgeon's hands with a very good-looking and well-shaped foot, yet a few months after he has returned in the condition I have just described. The surgeon should, therefore, always endea- vour to save the great toe, if possible; and if its amputation be absolutely necessary, I think amputation through the whole metatarsus, or even above the ankle better, for a working man certainly, than amputation through the great metatarsal bone. Amputation through the little metatarsal bone is not liable to these objections, at least not to the same extent, because the weight of the body is thrown more on the inner than on the outer side of the foot.—j. f. s.] 2732. Amputation through the intermediate metatarsal bones is thus (a) Zang, book iv. p. 184. AMPUTATION THROUGH THE FINGERS AND TOES. 685 performed. A longitudinal cut is made on each side of the diseased me- tatarsal bone, by carrying the knife close along it, to the place where it is to be sawn through, in such way, however, that, on the sole, the cuts run into each other, in a V like shape, and one of them, for instance, on the left foot that on the outer, and on the right that on the inner side,. should be three or four lines shorter than its fellow. The skin upon the dorsal surface of the foot is next cut through obliquely, from the angle of one to that of the other longitudinal wound, about two lines before the place of sawing. The skin is now to be drawn back, and all the soft parts separated by passing the knife between the bones on the sole and on the dorsal surface of the foot, in the oblique direction of the skin cut. The cleft cloth is now applied, the wooden splint passed in, up to the top of the side cut, and the bone divided obliquely with a fine saw from side to side. When the bleeding has been stanched, the neighbouring bones are brought together, and the skin brought over the end of the bone, by straps of plaster applied from the top of the foot downwards. The edges of the wound are to be kept together with several circular straps round the foot, and a simple covering (o). 2733. Amputation through the metacarpal bones is performed in exactly the same way as that through ihe metatarsal bones, already mentioned. Of the above modes of proceeding it must be decided which shall be followed, for the removal of some or all the metacarpal bones, except that of the thumb. For amputating through the metacarpal bone of the thumb, a flap must be made on the volar surface, the soft parts on the back of the hand, divided correspondently with the base of the flap ; then those in the space between the bones divided, and the me- tacarpal bones sawn off. [In amputating through the metacarpal bones, and specially if only the head of the hone be cut off, as commonly practised, when the whole finger is to be removed, as the other.fingers fall readily together, and do not produce the deformity which amputating at the knuckle does, it is better to cut through the bone with nippers than with a saw. Liston observes :—" In using the forceps, the flat side is applied to- wards the trunk, so that the surface which is left may be perfectly smooth. One. great advantage gained by employing the forceps is, that the palm can be left entire, the hand is much less deformed, the palmar arch is in general not interfered with, and the haemorrhage is accordingly more trifling." (p. 365.) I do not think the palmar arch is more safe with the nippers than with the saw, as the soft parts re- quire equal separation in both.—j. f. s.] VI.—AMPUTATION THROUGH THE FINGERS AND TOES. (Amputatio Digitorum Manus et Pedis, Lat.; Amputation der Finger und Zehen, Germ. ; Amputation des Doigts et des Orteils, Fr.) 2734. Amputation through the phalanges of the fingers is only indicated when some particular advantage is to be gained by keeping the stump, as in amputating the fore part of the second phalanx; in all other cases, dis- jointing the phalanx is to be preferred. In the toes, amputation must be restricted to that of the first joint of the great toe ; because, by preserving the ball of that toe, advantage is gained over disjointing it. Amputation of the phalanges, by means of sharp nippers, performed in the earliest times; or with the chisel, recommended by Heliodorus, Paulus jEgineta, and Al- bucasis, and subsequently by many other writers, both within and without the joint, (a) Zang, above cited, p. 187. 58* 686 OF EXARTICULATION. is entirely discarded ; and in general, the disjointing of the phalanx is preferred. Le Dran, Guthrie, Samuel Cooper, Langenbeck, Averill, Rust, Malgaigne, and Jaeger agree in preserving the phalanx, and as to the advantage of amputa- tion, though they differ from each other in regard to its application .to a single finger. Ru§t holds only with the amputation through the second phalanx of the fore- and ring-fingers, and forbids it on all the phalanges of the two middle-fingers. Langenbeck practises it on the first and second phalanx of the fore- and ring-finger, and on the first of the thumb and little finger. Averill, on the other hand, employs it only for the thumb and fore-finger. Jaeger thinks it maybe performed at the second phalanx of the fourth finger, with much advantage to the patient, especially the further forward it is done; and knows from experience that with the phalanges of the three outer fingers Which can be drawn into the palm, better resistance can be produced. Langenbeck, Zang, Rust, and Jaeger, are all in favour of amputation through the first phalanx of the great toe. 2735. In amputation through the phalanges, the skin having been pro- perly drawn back, a circular cut is made with a scalpel, the skuTagain drawn back, the tendons and periosteum divided, sawn through, and the bone then sawn through. If the skin on the back,of the finger be too much destroyed, or the phalanx too thick and broad, as that of the great toe, a flap may be made on the palmar surface, by thrusting the knife through there, and dividing the soft parte,on the back with a semicircular cut, which is better than a dorsal flap, or than a flap before and behind, or on the side. (Langenbeck, Zang.) In cutting the finger off with a chisel j {Dactylosmileusis, Lat.,) the fin- ger must be laid on its dorsal surface on a little wooden block, and held by an assistant, who at the same time draws the skin back: a sharp chisel, as wide again as the finger, is to be placed vertically on the palmar surface, and held with the left hand, and the finger is struck ofl with a smart blow* from a wooden mallet. In this way, which is gene- rally objected to as rough and barbarous, and only recommended by Graefe and Jaeger, there is not any splintering; the operation is quick and little painful, and the cure is not more tedious than in the operation with the circular cut (a). Mayor (b) has recommended the removal of the phalanx by a peculiar instrument, the tachytome, with which, at the same time, sufficient flaps of the soft parts are formed. Fourth Section.—OF EXARTICULATION, OR AMPUTATION THROUGH THE JOINTS. (Exariiculatio Membrorum, Lat.; Ablosung der Gleider, Germ.; Disarticulation, Fr.) Brasdor, Essai sur les Amputations dans les Articles; in Memoires de l'Aca- demie de Chirurgie, vol. v. p. 747. Walther, Ueber die Ampntationen in den Gelenken; in Abhandlungen aus dem Gebiete der praktischen Medicin, besonders der Chirurgie und Augenheil- kunde, p. 91. Landshut. Munzenthaler, Versuch iiber die Amputationen in den Gelenken. Leipzig, 1822. Lisfranc, Memoire sur les regies generales des Disarticulations ; in Revue Me- dicale, 1827, vol. i. p. 373. Scoutetten, La Methode Ovalaire, qu Nouvelle methode pour amputer dans les Articulations. Paris, 1827. 4to. Zanders, Die Ablosung der Glieder in Gelenk. Dusseldorff, 1831. (a) Schkeiber, Dissert, de Dactylosmileusi. Lips., 1815.—Jaeger, above cited, p. 250. (b) Revue Suisse. 1843. OF EXARTICULATION. 687 [Mann, Observations on Amputation at the Joints, in N. York Me- dical Repository, vol. 8, N. S. 1822. Hubbard, On Amputation at the Joints, in the same Journal, vol. 7.— g. w. N.] 2736. Amputations through joints are in some cases the only means of preserving life, as in amputations at the shoulder- and hip-joints. In other cases amputation in the continuity of the bone cannot be per- formed, on account of its shortness, as in some phalanges of the fingers and toes. And, finally, there may be a choice between exarticulation and amputation in the continuity of the limb, in which case the exarticu- lation must be preferred, if the patient will be benefited by preserving' a greater length of stump, as in exarticulations of the instep, in the knee- and wrist-joints. The danger of exarticulation, formerly held so great, is contradicted by the experience of modern times; and is by some, as Larrey, thought to be even less than in amputations in the continuity of limbs. 2737. The proceeding in exarticulation is very different. In general one or two flaps are formed, the size and direction of which depends partly on the nature of the joint, and partly on the injury which renders amputation necessary. Scoutetten has proposed a particular method (Methode ovalaire) for all joints, the peculiarity of which consists in an oval wound being formed, the extremity of which is near the joint, by two cuts being carried into one triangle. If the soft parts on the upper region of the joint be destroyed, they may be included by this method ; the edges of the wound do not retract unequally, as they often do in the formation of flaps, and the wound unites by a linear scar. In many joints, however, exarticulation, according to this method, is more difficult than that with flaps. Langenbeck and others had long previously operated in this same way in the re- moval of several joints. 2738. The processes of the bones most surely point out the place of the joint, which may even be discovered through the swollen parts. The knife should never be violently thrust into a joint, and in those joints, especially where their surfaces are locked into each other, not before their particular connexions have been cut through. In carrying the knife through the joint, its edge should always be directed towards the bone that is to be removed. 2739. It is frequently found in those cases where exarticulation is necessary, that the soft parts surrounding the joint are converted into a white, firm, lard-like substance. If this substance have not become soft, like pap, the flaps may be formed from it. By proper dressing this swelling may, however, be quickly lessened; and I have seen, in such cases, quick union take place just as well as in a perfectly healthy state of the soft parts (a). (a) Margot (Lisfranc), Sur les Amputa- ration; in Revue Medicale. 1827; vol. i. tions pratiques dans des Tissns lardacees, p. 41. revenus a Fetat normal a la suite de FOpe- [ 688 J I.—OF EXARTICULATION OF THE THIGH AT THE HIP. (Exarticulatio Femoris, Lat.; Ablosung des Schenkels aus dem Hiiftgelenke, Germ.; Disarticulation de la Cuisse, Fr.) Morand, Sur l'Amputation de la Cuisse dans son Articulation avec l'Os de la Hanche; in his Opuscules de Chirurgie, p. 176. Paris, 1768. Vohler; in same, p. 189. Puthod; in same, p. 199. Lalouette, An Femur in cavitate cotyloidea. aliquando arnputandum ? Paris, 1748; and in Halleri, Disputat. Chirurg., vol. v. p. 265. Barbet; in Prix de l'Academie de Chirurgie, vol. iv. p. 1. Couronne en 1759. Meckel und Unger, An Femur e cavitatecotyloideS. arnputandum? Halae, 1793. Moublet; in Journal de Medecine, vol xi. p. 240. Tallichet, De resecto Femore exarticulo. Halae, 1806. Larrey; in Memoires de Chirurgie Militaire, vol. ii. p. 180; vol. iii. p. 349; vol. iv. pp. 27, 50. Thomson, John, M. D., Report of Observations made in the British Military Hospitals in Belgium after the Battle of Waterloo, with some remarks on Amputa- tion. Edinburgh, 1816. 8vo. Guthrie, G. J., On Gunshot Wounds of the Extremities requiring the different Operations of Amputation, with their After-treatment. London, 1815. 8vo. The same translated into German, with remarks by Spangenberg. Berlin, 1821. Hedenus, A. G., Commentatio Chirurgica, de Femore in cavitate cotyloided am- putando. Lips., 1823. 4to.; with plates. Metz, H., Ueber die Losung des Oberschenkels aus dem Huftgelenke. Inaug. Abhandl. .Wurzburg, 1841. 2740. Exarticulation of the Thigh at the Hip-Joint, is, of all amputa- tions, the most dangerous; and the danger of the operation itself is con- siderably increased by the disease rendering it necessary. Of the cases hitherto published, in which this operation has been performed, the pro- portion of successful and unsuccessful results is about as 1 to 2| (a). Many die so long after, and in such way, that death cannot be directly ascribed to the operation. Jaeger (b), who has performed this operation successfully, has collected all the cases known to him, of which the following, which were successful, must be men- tioned, to wit, those of Baudens (c), Mayo (d), Sedillot (e), and Textor (/). Krimer (g), who lost a patient from sudden spasm, ten days after operating, ac- cording to Larrey's method, considers this operation inadmissible on account of its danger. The results up to the present time do not confirm this objection. There is also little advantage in Krimer's proposal of, instead of the exarticulation, tying the common iliac artery so as to cause death of the diseased extremity! 1 If the Surgeon hesitate to perform the operation through the joint, he could have no objection to perform it high up through the great trochanter, by which opening the joint would be avoided.—j. f. s.] (a) Perault; in Sabatier, Medecine Ope- Journal. 1831; p. 262.—M*cfallane, J., ratoire.—Larrey, Memoires, vol. iv. p.27.— Clinical Reports of (he Surgical Practice of Brownrigg and Guthrie; in Samuel the Glasgow Royal Infirmary, p. 182. Cooper's Dictionary of Surgery, p. 84. Edi- Glasgow, 1S32. In a child of two years. tion of 1838.—Dei.pech; in Revue Medicale. old, on account of a compound fracture.— 1824; vol. iii. p. 333.1828.—Wendelstadt; Co.*, W. S., Memoir on Amputation of the in Hufelanu's Journal, vol. vi. p. 110. Thigh at the Hip-Joint. London, 1845; fol. 1811.—Mott, V.; in London Medical and (6) Hamburger Zeitschrift, vol. iii. parti. Physical Journal, vol. iii. p. 228. 1827.— (c) In same. Wagner, Ueber die Exarticulation des Ob- (d) Lancet. 1836-7 ; vol. i. p. 110. schenkels aus dim Huftgelenke; in Rust's (e) Archive* generales de Medecine, vol. Magazin, vol. xv. p. 261.—Orton, J , A Case ix. p. 225. 1840. of Ampuiation of the Hip-Joint successfully (/) Metz, above cited. performed; in Med.-Chir. Trans., vol. xiii. (g) vo\ Graefe und von Walther's Jour p. 605.—Bryce, C; in Glasgow Medical nal, vol. xii. p. 121. EXARTICULATION OF THE THIGH, AT.THE HIP. 689 - 2741. So great extension of mortification as effects the thigh through- out its whole thickness, and such crushing of the thigh-bone, and of the soft parts as render flap-amputation below the great trochanter impossi- ble, can alone be considered as indications for amputation at the hip-joint. Caries in the hip-joint can never indicate this operation because the socket is always affected. [The first amputation through the hip-joint appears to have been performed by La Croix d'Orleans in 1748, on a boy of fourteen, both of whose lower limbs had become gangrenous from eating diseased rye; the first operation was through the right thigh, and four days after the left thigh was amputated at the nip-joint; he Seemed to be going on very Well, but died on the eleventh day after the second ope- ration (a). Perrault, of St. Maare, in Touraine, first operated with success in 1773 on a man who had gangrene of the thigh nearly up to the pelvis, in consequence of his thigh having been crushed between the pole of a carriage and the wall (b). The first reported case in England, but which was unsuccessful, is that operated on by Kerr (c) of Northampton, in] December 1774, (as appears from a letter from Harden of Northampton, to the late Sir William Blizard, for which I have to thank my friend Curling.) The patient was a girl between eleven and twelve years of age, with an abscess in the right hip-joint and hectic fever; after the operation Kerr " found not only the acetabulum carious, but also the adjacent parts of the ossa innominata to a very considerable extent." She went on very well till "the tenth or eleventh day, but then her respiration became more difficult, expectoration ceased, her mouth and tongue were covered with apthae, and she died on the eigh- teenth day from the operation." (p. 341.) This operation was performed with a single flap. John Thomson (d) states, he has "been informed it (amputation at the hip-joint) was performed in London by the late Mr. H. Thomson, Surgeon to the London Hospital," and imagines " it must have been his operation to which Mr. Pott al- ludes." (p. 264.) The passage referred to in Pott (e) is the following :—" I can- not say that I have ever done it but I have seen it done, and am now very sure I shall never do it unless it be on a dead body," (p. 394, in note reviewing the opinions of Bilguer and Tissot on amputation at the hip-joint.) Not being able to find any published account of this case, I have inquired of Curling whether there be any record of it at the London Hospital, and he informs me that there is not any. Proba- bly it did not succeed, as no notice is left of it; and whether Thomson or Perrault operated first, or whether Thomson operated before Kerr I cannot ascertain.—J. f. s.] 2742. The modes of proceeding in exarticulations at the hip-joint have been, since the time of Vohler, who broached the idea of this operation, variously laid down; many of these, however, rest only on experiments on the dead body, and depend generally on the condition of the soft parts, and the nature of the injury. The several modes of ope- ration may be disposed under the following heads—a. the circular cut; b. the flap cut, with one or two flaps ; c. the oval cut. a. The Circular Cut. 2743. Here belong the modes of Abernethy, Veitch, Kerr, and Graefe. 2744. According to Abernethy (/), the surgeon standing on the outer side of the limb, the femoral artery being compressed by the fingers upon (a) Barbet, above cited, p. 9. (d) Report of Observations made in the (6) Sabatier, Medecine Operatoire, vol. iv. British Military Hospitals in Belgium, after Pi 542. the Battle of Waterloo, with some Remarks ' (c) An account of the Operation of Ampu- on Amputation. Edinburgh, 1816. 8vo. tating the Thigh at the Upper Articulation, (e) Chirurgical Works, vol. iii. Edition of lately performed; in Medical and Philo- 1783. sophical Commentaries, by a Society in Edin- (/) Lectures, on authority of S. Cooper. burgh, vol. vi. 1779. 690 EXARTICULATION OF THE THIGH, the pubic bone, makes, an inch below the joint, two successive circular cuts, by which he divides the muscles from the great and little trochanter, cuts into the capsule, dislocates the head and divides the round ligament. 2745. Veitch (a) proposed making the amputation of the thigh below the joint in the common way with the circular cut, and sawing through the bone two inches below the cut. After the arteries have been tied the patient is to be placed on his side and a vertical cut made from the great trochanter to the wound, the muscles to be separated on the out- side of the thigh, the joint opened and the bone disjointed. Cole's (b) method, who amputated through the trochanter major and removed the neck and head, corresponds with this. Jaeger proceeded in the same way in his successful case, in which, whilst amputating through the upper third of the thigh with an external flap, he noticed the caries extending^higher between the lamelke, again sawed off the bone two or three inches higher, and even then finding the dis- ease extending up to the trochanter, he merely extended the upper angle of the flap on the fore and outer side two inches upwards, cut into the capsule without any great difficulty, then through the round ligament and easily removed the bone. The stump had everywhere flesh to spare which was however no evil, and after the cure it was six inches long, felt hard as if the bone was still remaining in it, and could in some degree be drawn inwards. 2746. Kerr (c) having first bent the thigh at a right angle with the trunk, made a cut through the skin, from behind the top of the trochanter obliquely backwards and downwards to the inside of the thigh, and from thence obliquely upwards to within two inches from the femoral artery; then a second beginning at the same place as the former, but carried in an opposite direction over the upper extremity of the trochanter, and from thence obliquely forwards and downwards to within the same distance of the vessel as in the former cut. He then cut through the muscles in the direction of the skin cuts, and separated the bone from the joint; grasped firmly the flap still undivided, and containing the artery, betwixt the fingers and thumb of his left hand, his fingers on the skin side of it, and his thumb on the muscular side, cut it through about four inches below the inguinal ligament, and tied the artery. [Kerr states further that the compression was so complete " as to prevent the loss of a single drop of blood, and the haemorrhage from the other arteries was full as inconsiderable as in any other amputation of the thigh. * * * The ligature fell off at the fourth or fifth dressing." (p. 341.) In Harden's letter it is further stated, that " two other small arteries only were taken up, and the blood lost during the operation was very trifling. The large artery was tied immediately above a branch going off which I think is called the profunda. Perhaps the operation could not be done with so much ease where the ligaments of the joint had not been previously destroyed, as was the case here."] 2747. According to Graefe's (e) experiments on the dead body, the femoral artery should be compressed with a roller, and Pipellet's or Moore's compressor; the skin is then to be divided with a circular cut, three or four fingers' breadth below the trochanter, and after having been moderately drawn back by an assistant, his leaf-knife {Blattmesser) is to be placed as deeply as possible on the outer side close to the edge of the retracted skin, the leaf sunk obliquely to the trochanter, drawn over the front to the inner side, so that its edge runs along the neck close to the (a) Edinburgh Medical and Surgical Jour- (c) Above cited, p. 339. nal, vol. iii. p. 129. 1807. (d) Normen zur Ablosung grosseres Glied- (b) Samuel Cooper's Surgical Dictionary, masseu, p. 117. p. 83, AT THE HIP, WITH SINGLE FLAP. 691 thigh-bone, and the cut completed in the usual way. If large vessels bleed which cannot be compressed by the assistant, they must be tied if not too close to the middle of the wound. The muscles are now drawn up by an assistant, and the fleshy parts first divided on the outside to the very point of the trochanter, with the blade of the leaf-knife kept directly upwards. An assistant now turns the knee outwards, the muscles are divided on the inner side with the blade of the leaf-knife directed upwards till the edge of the hip-socket appears. The transverse ligament is then divided with the edge of the knife held rather obliquely, and whilst the assistant rolls the head of the bone inwards and upwards, placing one hand below the trochanter, and the other on the inside of the knee, the operator pressing the knife firmly cuts through the capsular ligament on the inside. The assistant now carries the thigh far outwards till it forms a right angle with the side of the body, and the operator with one smart stroke cuts through the outer under part of the capsular ligament and the muscles still attached in this region, by which the head of the bone is completely freed. After stanching the blood, the wound is to be brought together obliquely with two sutures and strips of sticking plaster. b. The Flap Cut. * With a single flap. 2743. The operation of exarticulation with one flap is variously per- formed, according as it is a hinder (Puthod, Bryce ;) an inner (L'Alou- ette, Delpech, Lenoir, Langenbeck;) a front (Plantade, Manec) or an outer flap. 2749. According to-Puthod, the femoral artery having been first tied, the patient laid on his side and properly held, and the skin drawn up- wards by an assistant, a transverse semicircular cut is to be made through the skin, beginning on the inner hinder part of the thigh, and ending at the great trochanter. After drawing the skin back the tendon of the m. glutceus maximus is cut through, and by carrying the knife along the tro- chanter all the muscles there inserted are divided. The knife is now to be thrust into the joint below the tendon of the m. gracilis, and the cap- sular ligament cut across; after which the thigh is drawn upwards and inwards so that the head of the bone may project outwards and upwards, and then the stretched round ligament is cut through and the division of the capsular ligament completed. The muscles of the hinder inner side of the thigh are now' divided, four or five fingers' breadth from their in- sertion, and then the muscles on the inside at the top of the little tro' chanter cut through (a). Hunczorsky (b) directs the following mode of proceeding. After tying the femoral artery, the patient being laid upon his belly, and the thigh drawn somewhat inwards to render the m. glutaei tense, the skin is drawn back, and cut through three fingers' breadth below the trochanter major, and after it has been turned back, the m. glutaei are cut off at the trochanter; the knife is then carried outwards to make one flap of flesh which is raised up, and the cut being continued quite down to the joint, and the head twisted on itself, the other part of the capsular ligament and the round ligament are divided, and the operation completed by cutting through the muscles on the other side of the thigh. 2750. Bryce (c) compresses the femoral artery, and makes a transverse (a) Morand, above cited. (b) Anwekung zu Chirurg. Operationen, p. 256. (c) Above cited. 692 EXARTICULATION OF THE THIGH, cut on its inner side above the trochanter, above the highest part of the hip, ties the femoral artery, cuts through the capsular ligament, separates the head of the bone, and at last forms the lower flap. 2751. According to L'Alouette, the patient should be placed on his sound side, the femoral artery compressed with a tourniquet, the thigh stretched out, and an assistant draws the skin back. With a semicircular cut extending from the upper outer part of the great trochanter to the ischial tuberbsity, all the soft parts are cut through to the joint. The joint is now felt for with the nail of the left fore-finger, and the capsular ligament opened. The assistant rolls the thigh inwards, the projecting round ligament is divided with a button-ended bistoury, and the head of the bone dislocated by bending the thigh towards the chest, upon which the knife being carried round the capsular ligament, completely divides it, and a flap is formed four or five fingers broad, by bringing the knife down on the inside of the bone. 2752. According to Langenbeck (a), a transverse cut should be.made from the front of the thigh, not too near the femoral artery, on the outer side, down to the back part of the thigh, opposite the ischial tuberosity, which should divide the soft parts to the neck of the bone; then by turn- ing the knee inwards the exarticulation of the head is effected, and the inner flap is formed by cutting round the inner surface of the thigh. 2753. Delpech {b), who has performed this operation twice success- fully, after having tied the femoral artery, thrusts a single-edged knife two inches below the superior anterior spine of the ilium, between the m. sartorius and m. tensor vagincefemoris, to the neck of the thigh-bone, inclines the point inwards, and pushing it well into the cavity between the little trochanter and the neck, thrusts it through at the hinder part. The knife is now drawn down on the inside of the thigh-bone, and by cutting inwards a flap is formed about eight inches long. This flap is held back by an assistant, and any spouting vessel in it tied. The thigh is now inclined outwards, the capsular ligament divided seroicircularly, the head of the bone dislocated, the round ligament cut through, the knife carried behind the head, and the mass of muscle and skin divided by a horizontal cut. After the vessels are tied, the flap is brought over the wound and united with sutures an inch apart. Too much skin should not be preserved on the outer side, and it is better, if necessary, to make the inner flap longer. This method is a modification of Larrevt's, in which an outer flap is also formed. In this way, Orton, Clot, Cherubini, and Well have operated, excepting that Clot did not tie the femoral artery first. 2754. Lenoir (c) compresses the femoral artery, and standing on the outer side of the limb, which is inclined inwards, makes a transverse cut on the hinder outer side, draws the soft parts back, penetrates into the outer hinder part of the joint, and ends by forming an internal flap. An assistant compresses the artery in the flap till it is tied. 2755. According to Plantade {d), an upper or front flap should be (a) Bibliothek filr die Chirurgie, vol. iv. (c) Journal Hebdomadaire, vol. v. p. 205. p. 512. 1831. (b) Journal general de Medecine, vol. ciii. (d) Velpeau, Medecine Operatoire, vol. i. p. 429. 1828. p. 250. AT THE HIP, WITH TWO FLAPS. 693 formed by two vertical cuts on the sides, connected by a transverse cut, as in La Faye's mode of exarticulation at the shoulder. 2756. According to Manec (a), whilst the extremity is drawn outwards and a little bent, a double-edged knife is thrust betwreen the great tro- chanter and front iliac spine from above downwards, and from without inwards, between the neck of the thigh-bone and the muscles, and as the knife is. carried close down on the bone, a sufficiently long flap is cut, which an assistant raises, and compresses the artery found in it. The operator now passes the knife below the joint, places it on the inner angle of the wound, and divides to the outer angle all the soft parts to the bone. The capsule of the joint is then opened by a smart cut on its front, the head of the bone projected by abducting the thigh, the round ligament divided, and the rest of the capsule completely divided. After the forma- tion of the flap, the joint may be entered in front, and the hind parts separated by a cut from within outwards. 2757. If the condition of the soft parts only permit an outer flap, when the femoral artery has been either first tied or properly compressed, the knife must be thrust vertically, below the middle of Poupart's ligament, and the whole mass of soft parts cut through directly inwards. The thigh is now to be carried well outwards, the capsular ligament opened, the round ligament divided, the head of the bone pressed out of its socket, and by passing the knife round and drawing it down, the flap is formed. I have performed the operation in this way upon a living person. * * With two flaps. 2758. This mode of proceeding with twoflaps, varies according as it is performed with an inner and outer (A. Blandin, Larrey, Dupuytren, Lisfranc, von Walther), or with afore and hind flap (Wohler, Bell, Beclard, Begin, and Sanson), and according to the formation of one or other flap, and also whether by thrusting in the knife, or by carrying it from without inwards. 2759. A. Blandin ties the femoral artery first, and whilst he thrusts the knife into the lower angle of the wound, made for tying the artery, through the whole thickness of the thigh, he forms an inner flap, after- wards the outer one, and then proceeds to the division of the capsule and the exarticulation. 2760. According to Larrey, the femoral artery and vein should first be tied close to Poupart's ligament; then a straight sufficiently long knife thrust in on the front of the thigh and carried between the flexor muscles attached to the little trochanter, and base of the neck of the bone back- wards, so that it may come out directly opposite the point of entrance. The edge of the knife is now turned obliquely inwards, and with a stroke all the muscles on the upper and inner part of the thigh cut through, and an inner not very large, flap formed, which must be held back, and the bleeding vessels tied. The thigh is now to be abducted, so that the liga- ments may be stretched, the inside of the capsular ligament divided with a bistoury, then the round ligament, and whilst the abduction is increased, the head of the bone dislocated. The edge of the large amputating knife placed behind the head of the bone, is now carried close behind the great {a) Velpeau, Medecine Operatoire. 1839. Second Edition; vol. ii. p. 546. Vol. hi.—59 694 EXARTICULATION OF THE THIGH, trochanter, and the outer flap formed by cutting the muscles and skin obliquely. The spouting vessels are compressed by an assistant, and carefully tied, and after the surface of the wound has been properly cleansed, the flaps are brought into apposition, some sutures applied, the union supported by strips of sticking plaster, covered with lint, and a compress, and fixed with a proper bandage. Larrey (a) has subsequently recommended another method, in which after tying the crural artery, he makes a circular cut immediately below the great trochanter, through the skin, to determine the length of the flap. The inner flap must then be made either from without inwards, or from within outwards, according to the condi- tion of the parts. The capsular ligament is divided with the same knife, the head of the bone dislocated inwards, the round ligament divided, and the knife being carried over it into the skin-cut, the outer flap is thus formed. After tying the bleed- ing vessels, the ligatures are placed in the bottom of the wound, and a piece of oiled linen put into that angle of the wound nearest to the hip-socket, and then the flaps closed. Mott (b) forms the inner flap according to Larrey's method, by thrusting in the knife, and the outer flap by cutting from without inwards. 2761. According to Dupuytren (c), the operator, placed on the inner side of the thigh, and the artery being properly compressed, makes a semi- circular cut from the region of the upper front spine of the ilium, over the inner side to the ischial tuberosity, through the skin, draws it back- wards, cuts through the muscles in the same direction, thus forming an inner flap four or five inches long, turns this back, divides the capsule, and finishes the operation by the formation of the outer flap. According to Dupuytren's (d) earlier experience, the operator should stand on the outer side of the limb, with his hands on the upper part of the thigh, so that by gently moving he can discover the situation of the joint. From this place he makes a semi- circular cut passing three inches down, over the outer hinder part, and ending half an inch below the ischial tuberosity ; the skin is then drawn back and the muscles divided at its edge down to the bone. To this outer cut, the operator makes a second and corresponding one over the inner side of the thigh, which joins the first at the points where it begins and ends. The outer and inner flaps are separated up to the joint, and held back by an assistant. The capsule is divided by a circular cut, after- wards the round ligament, and then the head of the bone is removed. 2762. According to Lisfranc (e) the thigh is to be held extended by an assistant, and the operator, standing on the outside of the limb, draws a line from the front upper spine of the ilium, parallel with the axis of the thigh, and an inch in length, from the lower inner end of which, at a right angle to it or transversely a second line half an inch long. At the end of this latter line he thrusts the point of a long straight knife, with its edge following a line from its entrance to the upper outer part of the great trochanter. The blade of the knife now upon the outer side of the head of the thigh-bone, passes round it and projects at the middle hinder part of the buttock. By some strokes upwards and outwards, avoiding the great trochanter, the knife is carried along the thigh two inches, and thus the flap is completed. After the bleeding arteries have been tied, an assistant holds, the flap back. The knife is now carried round the neck of the bone, and again passed to the hind upper angle of the wound, the (a) Clinique Chirurgicale, vol. iii. p. 611. (6) Above cited. vol. i. p. 177.—Munzenthaler, above cited, (c) Lejons Orales, vol. iii. p. 363. p. 38.—Averill, above cited, p. 158.—Stme ; (d) Archives generales de Medecine. 1823; in Edinburgh Medical and Surgical Journal, vol. i. p. 171. vol. xix. p. 657. 1823.—Maingault, above (e) Archives generales de Medecine. 1823; cited, pi. viii. fig. 29. AT THE HIP, WITH TWO FLAPS. 695 soft parts, if necessary, being pressed inwards, to avoid the lesser tro- chanter, and a flap formed on the inner side of the bone, of the same length and form as the outer. The operator then grasps the thigh with his left hand, brings the edge of the knife perpendicularly upon the inner side of the head of the bone, which he runs round as much as possible, divides the capsular and round ligaments, and then cuts from within out- wards the rest of the capsule and whatever muscular fibres still remain attached. 2763. von Walther {a) compresses the femoral artery with a com- pressor against the pubic bone ; thrusts a double-edged amputation knife, three inches below the upper front spine of the ilium, at the outer edge of the m. sartorius, vertically down upon the neck of the thigh-bone, carries it outwards and backwards around it, and pushes it out two inches and a half behind the great trochanter, at a corresponding height to its point of entrance ; the knife now kept close to the bone, cuts two inches below the base of the trochanter obliquely outwards, and forms an oblong outer flap, which being drawn back, the exposed capsular ligament is cut into, the head of the bone dislocated outwards and downwards, and the round ligament divided. With a single-edged amputating knife he now passes through the cavity of the joint, behind the head of the thigh-bone and round the little trochanter, and continues two inches down along the inside of the thigh close to the bone. The,femoral artery and neigh- bouring vessels are now to be compressed, as high up as possible, by both the thumbs of an assistant placed upon the surface of the wound, and then the edge of the knife being inclined obliquely inwards, the opera- tion is completed by forming the inner flap. 2764. According to Vohler, the femoral vessels should be laid bare by a cut on Poupart's ligament and tied, a%nd then the patient having been placed on his belly, the skin and m. glutceus maximus are to be cut through two fingers' breadth below the ischial tuberosity, and the flap so formed drawn up ; the muscles attached to the trochanter are then cut through to the capsular ligament, which is opened whilst the thigh is slightly moved, and cut through forwards together with the muscles on the outer and fore part of the thigh, The vessels must be in part compressed, and in part tied. The hinder flap covers the wound. 2765. According to Bell (b), the femoral artery should be compressed by a torniquet against the pubic bone, and the thigh being bent on the groin, the skin and flesh of the thigh are^to be divided,with two circular cuts six inches below the joint, and every important vessel on the surface of the wound tied. Two longitudinal cuts are now made upwards from the circular, one behind from the head of the thigh-bone, and another before, so that two flaps are formed, one on the outer and the other on the inner side of the thigh. These are separated to expose the joint, the head of the bone dislocated, and if broken, it must be pulled out with the forceps. 2766. According to Beclard (c), the thigh should be slightly bent so as to relax the parts on its fore part, then in the middle of the space between the upper front spine of the ilium and the great trochanter, the (a) Graefe und Walther's Journal, vol. (c) Dictionnaire de Medecine et de Chi. vi. p. 11. 1824. rurgie pratiques, Article Amputation, vol. ii. (b) Above cited, vol. iv. p. 278. 1829. 696 EXARTICULATION OF THE THIGH, knife is thrust in horizontally, carried close over the neck and head of the thigh-bone, and the handle being raised a little, thrust through opposite its point of entrance. By drawing the knife down a flap is made six fingers' breadth long, which an assistant raises, and at the same time compresses the femoral artery. The front of the joint is now laid bare, the capsular ligament cut into, and afterwards the round ligament, the head of the bone dislocated by moving the thigh backwards, and the whole knife being carried behind the head, divides the back of the cap- sule, and forms the hinder flap of equal length with that in front. [Liston's (a) operation is the same as Beclard's, and he observes:—"This mode of getting at the head and neck of the bone is much preferable to that usually followed, and is in every respect safer, as he has more than once ascertained from actual practice on the living body. The fore part of the articulation is fully exposed immediately on the anterior flap being formed. The capsular ligament is cut by drawing the knife across determinedly, as if it were the intention of the operator to cut off the head of the bone. The round ligament and the posterior portion of the capsule are cut, and the blade of the instrument having been passed behind the neck and trochanters, the posterior flap is quickly formed so as to allow the limb to drop. The vessels on the posterior aspect are tied fast: then the femoral and those in the anterior flap, which had been commanded by the assistant, are uncovered one by one, and secured." (p. 387.)] 2767. Begin and Sanson (6) first make a semicircular cut, with its concavity upwards, through the skin and cellular tissue, beginning from the point of the great trochanter, carried over the front of the'thigh and ending at the tuberosity. The skin is drawn back and the femoral artery tied. The front flap is then made, either from without inwards, or from within outwards, by a thrust, and afterwards the hind flap, the one angle of which must correspond with the great trochanter and the other with the tuberosity. The operation is finished by the exarticulation of the head. * * * The Oval Cut. 2768. According to Sanson, the operator, standing on the outside of the limb, makes a cut obliquely from below upwards and from within outwards, beginning it four fingers' breadth below the perinceum, carrying it over the front of the joint, and ending it at the point of the great tro- chanter. This cut divides the skin and superficial muscles, and the femo- ral artery is now tied. A second cut beginning from the inner angle of the first, is carried over the hind part of the limb and united with the former at the point of the trochanter; it divides the skin and the mass of muscles as deep as possible. The knife is now passed into the first cut, its edge directed towards the hip-socket, the thigh dropped, by which the head is protruded, and then the capsular and round ligaments are divided. The knife is now carried round the head from within outwards, then backwards and afterwards inwards, care being taken that it do not for an instant leave the socket. This operation is very quick. 2769. Guthrie (c) gives the following mode of performing this ope- ration. An assistant standing on the opposite side> and leaning over, should compress the artery against the brim of the pelvis, with a firm hard compress of linen, such as is generally used before the tourniquet; he (a) Practical Surgery. (6) Sabatier, Medecine Operatoire, par Sanson et Begin, vol. iv. p. 682. (c) Above cited, pp. 363, 364. AT THE HIP, WITH OVAL CUT. 697 should also be able to do it with his thumb, behind the compress, if it be found insufficient. The surgeon standing on the inside, with a strong, pointed amputating knife of a middle size, makes his first incision through the skin membrane, and fascia, so as to mark out the flaps on cellular each side, commencing about four fingers' breadth, and in a direct line below the anterior superior spinous process of the ilium, in a well-sized man ; and continuing it round in a slanting direction at an almost equal distance from the tuberosity of the ischium, nearly opposite to the place where the incision commenced. Bringing the knife to the outside of the thigh, he connects the point of the incision where he left off with the place of commencement, bya gently-curved line, by which means the outer incision is not in extent more than one-third of the size of the in- ternal one. The integuments having retracted, the m. glutceus maximus is to be cut from its insertion in the linea aspera and the tendons of the m. glutceus medius and minimus from the top of the trochanter major. The surgeon now placing the edge of the knife on the line of the re- tracted muscles of the first incision, cuts steadily through the whole of the others, blood vessels, &c, on the inside of the thigh. The artery and vein, or.two arteries and a vein of the profunda is given offhigh up, are to be taken between the fingers and thumb of the left hand, until the surgeon can draw each vessel out with the tenaculum, and place a liga- ture upon it. Whilst this is doing the assistants should press with their fingers on any small vessels that bleed. The surgeon then cuts through the small muscles running to be inserted between the trochanters and those on the upper part of the thigh, not yet divided ; and with a large scalpel opens into the capsular ligament, the bone being strongly moved outwards, by which its round head puts the ligament on the stretch. Having extensively divided it on the forepart and inside, the ligamentum teres may now be readily cut through. The head of the bone is then easily dislocated, and two or three strokes of the knife separate any at- tachment the thigh may still have to the pelvis. The vessels are now carefully to be secured. The capsular ligament, and as much of the ligamentous edge of the acetabulum ought to be removed as can be readily taken away. The nerves, if long are to be cut short, the wound well sponged with cold water, and the integuments brought together iiLa line from the spinous process of the ilium to the tuberosity of the ischium. Three sutures will in general be required, in addition to the straps of ad- hesive plaster to keep the parts together. 2770. According to Scoutetten the patient is laid across the bed, and upon the opposite side to that on which the operation is to be performed ; his head raised a little above the pelvis, which should project beyond the bed, and in this position he is to be held by assistants, and the artery compressed at the groin. In operating on the left thigh, the surgeon, placing himself at the hinder part of the limb, assures himself with his left hand of the position of the great trochanter, and places his thumb or fore- finger upon it. With his right hand he thrusts iri the point of the knife, above the trochanter, vertically, sinks the blade a little and directs it for- wards and inwards four fingers' breadth below the crease of the groin and carries round the joint, whilst pressingit as deeply as possible through the parts. This cut is now left, for the purpose of carrying the knife, its 59* 698 EXARTICULATION OF THE THIGH, AT THE HIP, &C. point directed inwards and downwards, on the inside of the thigh, into the lower angle of the first cut; the knife is then directed obliquely back- wards to pass into the beginning of the first cut. It is very rare that in these cuts all the parts are at once divided down to the bone; most commonly it is necessary that the knife should be again entered into the wound to complete their division. To get at the capsule of the joint, the edges of the wound must be further separated and the undivided muscles cut through; and when the capsule is exposed, it must be cut into by placing the knife perpendicularly upon it; the limb being then dropped and the point of the toe turned outwards, the head of the bone partly protrudes from the socket, and where held by the round ligament, that must be divided with the point of the knife. The operator then lifts up the thigh in order to throw the head out, and running the knife round it divides the hind third of the capsule and the muscular fibres still remain- ing attached, and separates the limb. In operating on the right thigh, the surgeon places himself on the fore part of the limb, but the other proceedings are the same. 2771. Cornuau lays down the following mode of practice. The pa- tient being laid on his sound side, the operator with the fingers of his left hand ascertains the situation of the great trochanter, from the top of which he makes his first cut obliquely downwards and forwards to a right angle, formed by the union of a horizontal line from the ischial tuber- osity with another descending vertically from the upper front spine of the ilium. A second cut of equal length, and forming with the first an acute angle upon the great trochanter, passes obliquely backwards and down- wards to the middle of the thickness of the limb. The outer, hinder and fore part of the joint is now laid bare ; the capsular ligament must be opened as near as possible to the edge of the socket; after the division of the rest of the muscles which remain undivided by the first cut, the head is disloeated outwards, the round ligament easily separated, and the knife carried round the head towards the inner side of the limb. One assistant on the outside grasps the front flap of the wound, and in its thickness compresses the femoral artery; another draws the skin of the inside of the thigh upwards, whilst the operator with his left hand sup- porting the thigh, uses the knife till it come to the lower angle of the first cut, which finishes the division of the soft parts; rounds the inside of the wound, and completes the removal of the limb. 2772. Of these several modes of proceeding which have been proposed for the exarticulation of the thigh-bone, I hold Larrey's with the thrust of the knife, and the formation of an inner and an outer flap, {par. 2760,) or if the condition of the parts permit the formation of a single inner flap, {par. 2753) or of a single outer flap, {par. 2757,) the most preferable in regard to safety and ease of performance. It has also been, in most of the published cases, in which the operation has had a successful result, the way in which, with slight deviations, it has been performed. As to the objection in reference to the bleeding, the artery may be pre- viously tied, if there be no competent assistant to be intrusted with its compression. The wound should be brought together with sutures and strips of plaster, a piece of oiled linen put in the lower corner of the wound, and EXARTICULATION OF THE LEG. 699 the whole covered with lint and compress fastened with the inguinal bandage. Jaeger holds this dressing not always of use, recommends cold fomentations and applies the dressing just after suppuration has come on. II.—OF EXARTICULATION OF THE LEG AT THE KNEE. (Exarticulalio Cruris, hat.; Ablosung des Unterschenkels im Kniegelenke, Germ.; Disarticulation de la Jambe, Fr.) Bras dor, above cited. Textor, Ueber die Amputation im Kniegelenke; in neue Chiron, vol. i. p. 1. Velpeau, Memoire sur l'Amputation de la Jambe dans 1'Articulation du Genou; in Archives Generales de Medecine, vol. xxiv. p. 44. 1830. --------, Discussion Nouvelle a. l'occasion du Rapport de M. Larrey, sur l'im- portance et les avantages de l'Amputation de la Jambe dans Particle; in Journ. Univ. et hebdom. de Med. et Chir. Pratiques. Novembre, 1830. 2773. Amputation of the leg at the knee-joint, heretofore recommended by Guillemeau in 1612, and by Fabricius Hildanus, has been consi- dered by most writers as improper, or inferior to amputation through the continuity of the thigh. Brasdor, J. L. Petit, and Horn have recom- mended it; and Volpi, Kern, Textor, Langenbeck, Velpeau, and others have shown the applicability of this mode to those cases, where, in consequence of the extensive destruction of the front of the leg, amputa- tion through it is not possible, though there may still remain soft parts for covering the condyles, if exarticulation be performed. Many sur- geons object to it unconditionally, as Zang, Larrey, Dupuytren, and others. From Jaeger's (a) collection of the published cases of amputation at the knee- joint, it appears that of thirty-seven, about twenty-two have had a favourable, and fourteen an unfavourable result. 2774. Exarticulation at the knee-joint may be formed either with the flap or the circular cut. The patient is placed as in amputation* through the thigh; and the femoral artery compressed by an assistant, or with a tourniquet. 2775. In the amputation with the flap cut, it is best to make the flap from the back of the leg in the following manner :—After the femoral artery has been properly compressed, and the kg being held straight out, the assistant who holds the thigh, draws the skin back. With a straight small amputating knife, a transverse, or a semilunar (Sabatier, Textor) cut is made through the skin, from one condyle to the other. The leg is now bent to tighten the ligament of the knee-cap, and the surgeon grasp- ing it with the left hand, cuts through with the same knife, first this liga- ment, then the lateral ligaments, and lastly, the crucial ligaments. He then takes a larger amputating knife, carries it close to the hind surface of the shin and splint-bones, some little distance down, and forms, in cutting obliquely downwards, a flap sufficient to cover the exposed joint- surfaces. After the vessels have been properly tied, the flap from behind is brought close into contact with the front edge of the skin, and the dressing applied, as after amputating the leg with a single flap. The following modes of proceeding are less convenient:—First, According to (a) Handworterbuch der Chirurgie, vol i. p. 363. 700 EXARTICULATION OF THE FOOT Blandin (a), when the patient has been placed on his belly, and the femoral artery is compressed, a catlin is passed at the joint, above the bones from one side to the other through the soft parts, and carried down to form a flap about six inches long. An assistant holds back this flap, whilst a semicircular cut is made at its base, from one angle to the other, over the front of the joint below the knee-cap, through the teguments, the joint is then opened, and by the division of the lateral and crucial ligaments, and of the ligament of the knee-cap, the operation is completed. Second, The formation of two flaps. According to Rossi (b), a cut is to be made on both sides of the knee, which* are connected with each other by an arch, and the two flaps thereby described, are dissected back and turned over: the ligament of the knee-cap is then divided, the knife carried into the joint and every thing cut through. Accord- ing to Maingault (c), a narrow straight knife is to be thrust through the joint, on the inside of the thigh, behind the knee-cap, but before and below the condyle, and by carrying it down the ligament of the knee-cap, the general coverings are cut through to the tubercle of the shin-bone. This flap is then raised, the lateral and crucial ligaments cut through and by drawing the knife down, the hinder flap is formed. According to Kern, the flap should be formed by two cuts from the outer sides of both condyles of the thigh-bone towards the spine of the shin-bone, of a V shape, and four or five inches long, and after dividing the ligaments, a hind flap of four inches is formed. 2776. In the circular cut, according to Velpeau, the leg being stretched out, a circular cut, three or four fingers' breadth below the knee-cap, divides the skin, which is then dissected up and turned back, and whilst the thigh is grasped with the left hand, and a little bent, the ligaments are divided from before backwards, and the muscles and vessels lying behind, are cut through at a stroke. After the vessels are tied, the wound is brought together vertically, or horizontally. Velpeau has twice operated in this way successfully, and has given up the method which he formerly recommended. According to Cornuau, it is less advantageous to divide the soft parts by a circular cut at the edge of the skin, after it has been turned back, and then by dividing the lateral ligaments, to penetrate into the joint. Equally so is the oval cut after Baudens' method ; he makes a mark with a pen from the spine of the shin-bone three fingers' breadth below the ligament of the knee-cap, which he carries obliquely backwards, and from below upwards, towards the knee- cap, and ends only two fingers' breadth below a line corresponding to the ligament of the knee-cap. An assistant draws the skin of the knee upwards, the operator makes a cut along the marked line of the oval, the skin is then drawn back on the joint, and this, together with the aponeurosis and tendons, cut through and the lips of the wound united lengthwise. If the knee-cap be diseased, the skin is to be separated from it, and itself from the tendon of the m. rectus and the capsular ligament, which is better then making a fl shaped cut through the skin, as recommended by Brasdor. Exarticulation of the Ankle-Joint, proposed by Brasdor and others, and entirely rejected by most surgeons, but in modern times recommended by Lisfranc, Mal- gaigne, Baudens, and Jaeger, is in every respect inferior to amputation through the leg, as it is always more difficult and dangerous, and always forms a bad stump, and unfitting for the application of an artificial foot. [II.*—OF EXARTICULATION OF THE FOOT AT THE ANKLE. (Exarticulatio Pedis, Lat.; Ablosung des Fusses im Fussgelenke, Germ.; Disarticula- tion du Pied, Fr.) This operation was long since performed successfully in France, once by Sedillier, de Lavall, and Brasdor ; but seems to have been given (a) Dictionnaire de Medecine. Article Amputation, vol. ii. p. 282. (b) Elem. de M6d. Operat, vol. ii. p. 227. Turin, 1S06. (c) Above cited.—Froriep's Chirurg. Kupf. Taf. pi. cvii. fig. 1,2. AT THE ANKLE. 701 up from a notion that the projections of the ankles below the base of the shin-bone would prevent the scar bearing the weight of the foot, notwith- standing Brasdor had distinctly stated that these processes soon became blunted, that the ends of the bones rounded, and that there was plenty of skin to cover a great part of the wound. Velpeau {a) performs this operation by making two semilunar flaps of skin, one upon the instep, and the other above the heel, twelve or fifteen lines before and behind the joint, and meeting to form another semilunar cut on each side about an inch below the ankles. The tendons and liga- ments are then to be,divided as close as possible to the joint; after which the astragalus is easily removed from its mortise, and with it the whole foot. The flaps are brought together transversely, so that the angles enclose the points of the ankles. Baudens' operation differs from Velpeau's in a single flap being made by carrying a knife down to the bone, from the insertion of the Achilles' tendon behind the heel, on each margin of the sole of the foot, nearly as far forwards as the crease of the toes, and these are connected by a trans- verse cut of a semicircular form like a gaiter across the whole dorsal sur- face of the foot, which must descend a little lower on the inner than on the outer edge, to avoid including a small bundle of muscular fibres be- longing to the plantar surface. The flap thus marked is now taken hold of with the left hand and firmly drawn, so that with some smart strokes of the knife, the whole of the soft parts, including the plantar arteries, should be shaved off close to the bones, as far back as the points of the ankles. The anterior ligament is then cut through, and the line of the joint laid bare, but without opening it further, the saw is placed upon it, and worked from before backwards, so as not merely to remove the malleolar processes, but also the hind edge of the tibial mortise, in order to make the surface level, and leaving the joint-cartilage only in front and in the middle, so that it hardly forms a third of the whole bony surface. The ligaments and soft parts untouched are now to be separated with the knife and the Achilles' tendon scraped off as closely as possible to the heel-bone. The posterior and anterior tibial arteries require tying, and the flap dropping by its own weight upon the wound is fixed with sutures. Syme (6) introduced the operation of amputation through the ankle- joint into this country, making his flaps like Velpeau, and sawing off'the malleolar processes, as in Bauden's amputation just above the joint, but not meddling with the base of the ^hin-bone, unless it be diseased. The removal of the bony projections of the ankles was a very happy thought, although Brasdor's observation proves that they will become blunted, and Syme is justly entitled to the merit of having perfected this opera- tion. In his first operation he cut across the integuments of the instep in a curved direction, with the convexity towards the toes, and then across the sole of the foot, so that the incisions were nearly opposite each other. The flaps thus formed were separated from their subjacent con- nexions, which was easily done, except at the heel, where the firmness of texture occasioned a little difficulty. The disarticulation being then readily completed, the malleolar projections were removed by means of (a) Nouveaux Elemens de Medecine Ope- London and Edinburgh Monthly Journal of ratoire, vol. ii. p. 497. 1832. Medical Science, vol. iii. p. 93. 1843. (b) Surgical Cases and Observations: in 702 EXARTICULATION OF THE FOOT AT THE ANKLE. cutting pliers. Subsequently he thought these flaps too long (c), and states that a line drawn round the foot midway between the head of the fifth metatarsal bone and the malleolus externus, will show their extent anteriorly, and that they should meet a little way farther back, opposite the malleolar projections of the tibia and fibula. Care is to be taken to avoid cutting the posterior tibial artery before it divides into the two plantar arteries for fear of partial sloughing of the flap. If the articula- ting surfaces of the tibia and fibulahe diseased, a thin slice of these bones should be sawn off. Handyside {b) imagines that the operation can be much more easily and readily performed by the method of antero-lateral flaps, as the dis- section of the os calcis from the soft part of the heel is thus much more easily effected, the great bruising and twisting of the soft parts, which occurs in the other mode of disarticulation, is thus happily avoided, and primary union is thus more likely to take place. The operation could, if necessary, be still further facilitated also by incising the pad of the heel backwards from the point where the two antero-lateral incisions meet. To this it may be fairly replied, that there is no necessity for twisting and bruising the soft parts, and that the side-flap proposal directly does away with one principal advantage of Syme's operation, to wit, that " the dense textures provided by nature, for supporting the weight of the body, might be still employed for the same purpose;" and on which account it should be preferred to the side-flap scheme. Syme considers this opera- tion applicable to many diseases and injuries of the foot, in which, exci- sion of the affected bones, or amputation of part of the foot being ineffi- cient, the practice previously followed had been that of amputating below the knee. The advantages promised by amputation at the ankle-joint instead of the operation" near the knee are, first, that the risk of life will be smaller; second, that a more comfortable stump will be afforded; third, that the limb will be more seemly and useful for support and progressive motion. The risk of life must be less, because the parts divided and re- moved are not nearly so extensive as when the leg is amputated, hardly indeed exceeding those concerned in Chopart's operation; because there is less room for haemorrhage either immediate or secondary, owing to the smaller size of the vessels cut, which are merely the branches of the pos- terior tibial, and the anterior tibial artery very near its termination; and because the cavities of cylindrical bones not beingopened, the danger of exfoliation from the dense osseous texture and of inflammation in the medullary veins is avoided. The stump will be more comfortable, be- cause it is formed of parts peculiarly well calculated to protect the bone from injury, and not disposed to contract like the muscular tissue; be- cause the cut ends of the nerves being smaller will be less apt to enlarge and become the seat of uneasy sensations; and because the absence of exfoliation ensures complete union of the integuments over the bone, and the limb will be more useful, as well as seemly, from full play being af- forded to the knee-joint, without the embarrassment of an imperfect stump. This operation has been successfully performed eight times by Syme himself, and also by several others. (a) Same; in same, vol. iv. p. 647. 1844. (b) Cases in Surgery; in same, vol. v. p. 789. 1845. [ 703 ] II.**-OF EXARTICULATION OF THE TARSAL BONES. I am rather doubtful whether this subject should be here noticed, or whether it should be referred to excisions; but upon the whole it may perhaps be considered as belonging rather to exarticulations. The needfulness of removing or exarticulating either of the tarsal bones seems to be restricted to the astragalus and navicular bone in cases of compound dislocation ; but I have not known any instance in which the latter has been removed. In very rare instances the astragalus may be thrown out from all its connexions through the skin by violence; a case of this kind occurred some years since to my late friend Hammond of fcouthgate, in which his patient having jumped out of a gig, with which his horse had run away, the astragalus was jerked completely through the skin on the front of the instep, and hung only by a few shreds of cellular tissue, which having been divided, the bone was removed and the patient recovered. More commonly the astragalus is merely detached and thrown out from the cup of the navicular bone, which happened in a case of my colleague Green's several years since {a), the so-called head of the bone bursting through the skin below the inner ankle. If the bone cannot be replaced, it must be exarticulated from the ankle-joint above and from its connexion with the heel-bone below. The operation is tedious and tiresome, and it is requisite to cut through the remains of the inner plantar ligament and the other ligaments which connect the bone to the shin- and splint-bones, in doing which the point of the knife must be kept close to the astragalus, and if possible, to avoid division of the plantar arteries if they be not already torn through.—j. r. s.] [On removal of the Astragalus, see paper by Norris in the American Journal of the Medical Sciences, vol. xx. 1837.—g. w. n.1 III.—OF EXARTICULATION OF THE FOOT BETWEEN THE ASTRA GALUS AND NAVICULAR BONES, AND THE HEEL- AND CUBOID BONES. a«w uubuijj (Exarticulatio per montem Pedis, Lat.; Ablosung des Fuses zwischen dem Sprung-und Kahnfbrmigen, und dem Fersen-und Wiirelformigen Beines, Germ.; Disarticula- tion Partielle du tarse, Fr.) 2777. Amputation of the foot through the nearly right lined joints be- tween the astragalus and navicular, and the heel- and cuboid bones in- dicated py Garengeot and Heister, was first performed by Du Viviers {b) and Chopart (c), but first described by the latter, whence its designa- tion, Chopart's excision of the foot; and in Germany, specially, parti- cular rules were laid down for it by Walther (d) , and its great pre- ference to the previously grievous amputation of the leg pointed out (e). ^T^^^TaV11 Dislocations' P- 33°- Y"L«V-P- 471—Dictionnarie des Sciences' New Edition, 1842. Medicates, vol. i. p. 497. (6) For DuViver's Case, see Hunczovsky, (d) Abhandlungen aus dem Gebiete drr Medicinisch - chirurgische Beobachtungen prakt. Medicin, u s w p 143 auf seinen Reisen, p. 244. Wien, 1783. («) Langenbeck, Bibliothek fur Chirurgie (c) Fourcrov's Journal; La Medecine vol. iii. p. 746, pi. i. fig ] 3—Klein ah eclairee par les Sciences physiques, vol. iv. cited, p. 27.—Chelius, Be'richt uber Hi! Paris, 1792.—Richter's Chirurg. Bibliothek, Chirurg. Klinik, p. 20. 704 PARTIAL EXARTICULATION OF TARSAL BONES. 2778. The diseased conditions suitable for this operation are rare, and are only crushings and carious destruction not extending beyond the first row of the tarsal bones, and in which the state of the soft parts permits the formation of a flap sufficient to cover the exposed joint-surfaces. 2779. The mode of proceeding in this operation varies acccording as the condition of the soft parts permits the formation of two flaps or only one. 2780. The patient is placed in the same position as in amputation through the thigh. The femoral artery is compressed above the knee with a tourniquet; an assistant grasps the foot above the ankle, and draws the skin as much as possible upwards. The operator holds the front of the foot with his left hand, placing the tip of his forefinger on the promi- nence of the navicular bone, and the flat of his thumb behind the promi- nent end of the metatarsal bone of the little toe; and a line drawn across the dorsal surface of the foot, behind the thumb and forefinger, sufficiently points out the place of the joint. The operator in this way grasps the right foot of the patient with his own left hand, its palm being directed towards himself; but in operating on the left foot, the back of his hand is towards the operator. This indication of the joint is by far more certain than the direction to find it, a finger's breadth beneath the lower end of the shin-bone, or half an inch below the outer, or an inch below the inner ankle. 2781. If an under flap only be to be formed, the fingers of the left hand having been placed as directed, a strong scalpel is to be carried immedi- ately behind them from the one edge of the foot, about four or five lines above the sole of the foot, over the instep to the opposite side, and the skin and tendons cut through. The first cut generally opens part of the joint. The front of the foot, then grasped with the left hand, the thumb upon the back and the other fingers upon the sole, is borne downwards and outwards, so as to stretch the ligaments between the astragalus and navicular bone, and then the knife is carried into the joint between them. As this is done the whole foot is drawn more downwards, and the liga- ments between the heel-and cuboid-bones divided. The front of the foot is now much pressed down, a large amputating knife entered into the joint, and the inner being held a little higher than the outer edge of the foot, carried down with the edge close to the plantar surface of the metatarsal bones, cutting the flap obliquely downwards at their junction with the phalanges of the toes. In this way a flap is formed of proper length without any measuring being required. 2782. After tying the vessels and cleansing the wound, the flap is brought over the joint surfaces of the astragalus and heel-bone, so that its edge may be properly applied to that of the upper cut, and in this posi- tion it is to be fixed with sticking plaster passing from the sole over the instep, and from the one side of the flap to the other. Four compresses are then to be fastened with a circular bandage on the four sides of the stump, of which two are cleft, so that one cleft and one not cleft are opposite each other. The wound is now to be covered with a pledget and lint, the uncleft compress passed through the cleft one, drawn together diagonally and its ends fastened by some turns of the circular bandage. PARTIAL EXARTICULATION OF TARSAL BONES. 705 2783. If an upper and under flap be formed, the joint having been determined as above mentioned, one cut is made on the inner edge of the foot, from the projection on the navicular bone, and a second on the outer side, beginning from the junction of the heel and cuboid bone ; and the length of these cuts is to be from two to three fingers' breadth, accord- ing as the lower flap is formed larger or smaller. The lower ends of the side cuts are to be connected by a transverse one across the instep, and thus the flaps are to be separated together with all the tendons and muscles from the bones up to the beginning of the side cuts, and turned back. The prominence of the navicular bone is now againfelt for, the foot grasped, as in the former case, with the left hand, and at the edge of the turned-back skin, close behind the projection of the navicular bone, the connexion between it and the astragalus is cut through, and then whilst the front of the foot is much pressed down, the connexion between the cuboid and the heel-bone is also cut through. The under flap is then formed with a large amputating knife in the way directed in the last paragraph. If the above-mentioned indication of the joint be properly followed, it cannot be Well missed. It may here be remarked to the little experienced, that in dividing the connexions between the navicular bone and astragalus, the knife frequently enters behind the head of the astragalus. If the knife be passed between the navi- cular and cuneiform bones, which is only possible by complete departure from the wiles laid down, the mistake is soon discovered by the joint-surfaces of the cunei- form bones, and by the obstacle which the cuboid offers to its complete separation. Maingault (a) begins the operation by forming the under flap, cutting through the tough ligaments on the plantar surface, and completing the operation by dividing the parts on the instep. 2784. Langenbeck, Klein, and RicheRand consider the formation of an upper flap useless, because the higher the scar is with a single under flap the less injury is it exposed to, and because this flap on account of its great toughness is more fit for covering the wound. Some consider that the upper flap should merely be formed by dissecting back the skin, as the tendons are liable to a tiresome suppuration, and may be thrown off. Experience has, however, proved to me that by the formation of an upper flap according to Walther's method, that is, when every thing is separated from the bones, such adhesion of the tendons, especially of the m. tibialis anticus, will follow ; that the heel cannot be so far drawn up by the operation of the gastrocnemial muscles as in the formation of a simple plantar flap or of an upper flap merely of skin. If after this ope- ration the heel be considerably drawn up, the foot will be little useful for walking; and under such circumstances the subcutaneous division of the tendo Achillis has been recommended. Scoutetten's oval cut only remains to be mentioned, in which from the middle of the line of the joint.upon the instep, a cut is made passing forwards and downwards to- wards the roots of the metatarsal bones, and connected by a transverse cut upon the sole of the foot in the region of the bases of those bones. The skin is then drawn back, and the exposed joint divided. Blasius recommends his oblique cut. (a) Bulletin des Sciences Medicales. Nov., 1829; p. 60. Vol. hi—60 [ 706 ] IV.—OF EXARTICULATION OF THE METATARSAL BONES. (Exarticulatio inter Tarsum et Metatarsum, Lat.; Ablosung der Mittelfussknochen aus ihrer Verbindung mit den Fusswiirzelknochen, Germ.; Disarticulation des Metatarsiens, Fr.) Hey, William, Practical Observations in SuTgery, p. 547. Second Edition. Vilerme, Sur les Amputations partielles du Pied ; in Journal de Medecine, par Le Roux, etc., vol. xxxii. p. 156. 1815. Lisfranc he St. Martin, Sur l'Amputation partielle du Pied. Paris, 1815. Ficker, Ueber die Amputation des Fusses zwischen der Fusswurzel und Mittel- fussknochen ; in von Graefe und von Walther's Journal fur Chirurgie und Augen- heilkunde, vol. iv. p. 90. Scoutetten, Memoire et Observations sur l'Amputation partielle du Pied dans 1'articulation tarso-metatarsienne ; sur l'Amputation metacarpo-phalangienne en to- tality, et Reflexions sur l'Amputation phalango-phalanginienne ; in Archives gene- rales de Medecine, vol. xiii. p. 54. 1827. 2785. The metatarsal bones may be removed from their connexion with the tarsal bones either all together or singly. The flrst operation should always be performed if the destruction do not extend over the tarsal bones, and the advantage of this operation is greater than Chopart's excision, as thereby a larger portion of the foot and the insertion of the m. tibialis anticus is preserved, and the drawing back of the heel pre- vented. But if the greater difficulty of this operation be considered on account of the irregularity of the joints, and the impossibility of closely applying the flap, and that by the performance of Chopart's excision, according to the mode recommended by Walther, the drawing back of the heel can be prevented, this preference may seem less considerable. 2786. Hey first makes a mark upon the back of the foot, at the con- nexion of the metatarsal with the tarsal bones, and an inch beyond this a transverse cut through the skin and muscles of the bones of the metatar- sus. From each end of this, he carries a cut along the inner and outer edge of the foot towards the toes, separates the skin from the metatarsal bones, and all the integuments and muscles forming the sole of the foot, from the under part of the metatarsus, with the edge of the knife close to the bone, up to their joints, detaches the four lesser metatarsal bones at this joint, and saws through the projecting part of the first cuneiform bone connected to that of the great toe. After the blood is stanched, the flaps are brought together with sutures. Scoutetten, also, directs that the first cuneiform bone should be sawn off; the operation of the m. tibialis anticus is not thereby interfered with. 2787. According to Lisfranc, the operator, after having ascertained the position of the parts, grasps the fore part of the foot with his left hand, and with his right the catlin, then places, if he operate on the right foot, the hind part of its edge behind the projection of the fifth metatarsal bone, so that the edge forms a. right angle with the axis of the joint; he divides the soft parts from without inwards, and a little from above downwards, and when he feels he has penetrated into the joint of the metatarsus with the cuboid bone, he raises the handle of the knife and passes through the first two. joints with the point held vertically, then through the third joint, when he inclines it towards the toes, for the pur- pose of getting round the outer projection of the third cuneiform bone. He then finishes the division of the soft parts above by a cut which ends EXARTICULATION OF METATARSAL BONES. 707 beneath the inner projection of the first metatarsal bone. He divides the cellular connexion if the retraction of the skin be not sufficient. The hand of the operator is held prone, and with one cut before and another behind, he gets round, with short strokes from before backwards,the pro- jection just mentioned, finds the joint at about the distance of a line, where it is distinguishable by the absence of any obstacle, and by a little depression ; he readily passes through this by describing a slight curve, the concavity of which corresponds to the cuneiform bone. Without giving the foot any other direction, and without the blade of the knife leaving the joint, the operator directs it, held in the same position it had in passing over the inside of the first metatarsal bone, between that bone, the first cuneiform, and the second metatarsal bone ; he inclines the handle of the knife for- wards so that its point may penetrate deeper, and then raises the handle suddenly towards the tarsus, so as to divide the ligaments. He proceeds to the hinder articulation, which he dislocates a little, brings the edge of the knife in a transverse direction, and ends by dividing the connexion of the second metatarsal bone with the third cuneiform, by an opposite movement to that which had divided the connexion of the first metatar- sal with the first cuneiform bone, taking care to bring the point of the foot slightly inwards. Attention in using only the point of the knife in the exarticulation has the advantage of not injuring the soft parts in the sole, and of penetrating more easily between the bones. The operator continues the operation by dividing the hinder ligaments, holding the parts to be removed, vertically, and not much dislocated. He then carries the whole edge of the knife forwards, close to the hinder edge of the metatarsal bones, and forms a flap from the sole of the foot, two inches long on the outer and inner side, and thick in front, so that it readily unites. After tying the vessels and cleansing the wound, the flap is brought up over the surface of the wound, kept in its place with sticking plaster, covered with lint and compress, and supported by a moderately tight bandage. The foot is now placed in a rather raised position upon a pillow in the bed, the leg half bent and laid on its outer side, so that the discharge from the wound may readily escape. If the operation be performed on the left foot, the operation must be begun on the inside of the foot, and the above-mentioned directions of the knife must be followed out. 2788. Munzenthaler (a) gives the following description of tbis ope- ration. The operator, placed on the inside of the limb, passes his finger to the bone which bounds the tarsus, glides it from the toes to the ankle and acquaints himself with the projections which the connexion of the metatarsal and tarsal bones form at some parts. He marks the place of the joint with the thumb and fore-finger of the left hand, places the edge of the knife behind the hind end of the fifth metatarsal bone, passes over the dorsal surface of the foot, at first from behind forwards, then from before backwards, and thus makes a semicircular cut which ends half an inch before the pit observed at the side of the joint of the cunei- form with the metatarsal bone. The knife is brought back again into the wound from within outwards, whilst an assistant draws the skin back towards the ankle, and thus the extensor tendons of the toes of both the (a) Above cited, p. 29. 708 EXARTICULATION OF m. peroneus longus and brevis, the artery, and so on, are cut through. The operator now brings the point of the knife vertically behind the hind end of the fifth metatarsal bone, directs it inwards and forwards, cuts through the joint of the two last metatarsal bones, and divides the liga- ments transversely. He now leaves this part and turns to the inside of the foot, and here directing the point of the knife upwards, and its edge outwards, cuts through the ligaments from below upwards, and from be- hind forwards, and penetrates the space between the bones, in the di- rection of a line running to the middle of the fifth metatarsal bone. To disjoint the second metatarsal bone, the knife performs a rotatory move- ment, and its edge is diiected forwards. The operator brings the point obliquely from below upwards, between the great cuneiform and the second metatarsal bone, and divides the soft parts near its inner edge, then raises the handle of the knife, cuts through the ligaments, and thus gets to the hind part of the mortise which the second forms with the other cuneiform bones. He now again, holding the knife as usual, directs the point from without inwards, and cuts through the dorsal ligaments with- out penetrating the joint; for the separation of the upper surface of the bones thereby connected, a slight pressure of the left hand upon the end of the foot is sufficient. If the fibrous parts oppose the dislocation of the metatarsal bones they must be gradually cut through. The foot is now to be held horizontally between adduction and abduction, and the sur- geon cuts through the plantar ligaments of the joint, separates the soft parts from the hinder ends of the metatarsus, carries the knife round them, cuts close to the lower surface of the row of bones, and forms, by cut- ting out obliquely, a flap, which on its inner side is two, and on the outer side, only one inch long. If the left foot be operated on, the operator stands on the outside of the limb, cuts from the tibial to the fibular edge, and proceeds with the operation as directed. If the projection of the fifth metatarsal bone cannot be properly made out, a point two inches before and below the outer ankle, will sufficiently distinguish it. The projection on the first metatarsal bone, if it cannot be felt, will be found nine lines below a line supposed to be drawn from the ^prominence of the fifth metatarsal bone, directly to the inside of the foot. If the operation be performed on a young person before puberty, where the pro- jection formed by the first cuneiform bone is still cartilaginous,.this process should be cut through with the edge of the knife almost in the same line in which the joints of the second, third, and fourth metatarsal bones are found. 2789. Of the exarticulation of the single metatarsal bones, must be considered, flrst, the exarticulation of the three or four outer metatarsal bones, whilst that of the great toe is preserved: second, the exarticula- tion of the great and little metatarsal bones: third, the exarticulation of one of th,e middle metatarsal bones. 2790. The preservation of the great toe, when the other metatarsal bones are removed, is a great advantage to the patient. A cut should be made in the space between the great and second toe, and a second along the outer edge of the foot, and both connected at one or two fingers' breadth below the tarsal joint on the instep; the skin is then drawn back, and the joint opened from the outer edge of the foot, after which a large flap is cut from the sole (a). The outer two metatarsal bones are removed in the same way. (a) Key; in Guy's Hospital Reports, vol. i. p. 244. 1836. METATARSAL BONES. 709 2791. The exarticulation of the metatarsal bone of the great toe is per- formed most conveniently, in the following way:—A small amputating knife is entered on the outer side of the great toe, at a stroke, through the soft parts, between the metatarsal bone of the great and second toe up to the joint of the former, with the cuneiform bone. Then the meta- tarsal bone of the great toe being drawn inwards, the whole edge of the knife is carried into the joint, and whilst this is done the great toe is pressed forcibly inwards, till the metatarsal bone is completely dislocated. The edge of the knife is then carried round the joint-surface, and being kept close to the outer side of the metatarsal bone at its connexion with the great toe, forms a flap sufficient to cover the whole surface of the wound. The dressing is like that in amputation through this bone. 2792. If the state of the soft parts will not allow the formation of a side flap, a lower or upper flap must be made in the same way as in am- putating through the bone {par. 2729) after a longitudinal cut has been made on the outside of the metatarsal bone of the great toe. Or Lan- genbeck's or Scoutetten's method may be adopted ; though the opera- tion is then more tedious and difficult. When the situation of the joint has been found by feeling with the finger, and the place (par. 2788 note) marked, the point of the left fore-finger is put on this part, and the other fingers, excepting the thumb, placed on the sole, for the purpose of sup- porting the foot. A cut is now made, beginning two lines behind the joint, and continued obliquely, from within outwards to the commissure of the toes, to the base of the first phalanx opposite the crease of the joint, on the sole. This cut is now left, and the bistoury, placed on the inside of the phalanx at the lower angle of the cut, is carried up along the inner side of the toe and metatarsal bone, obliquely from within out- wards, to the beginning of the cut. After dividing the skin, the knife is carried anew into the wound, and successively cuts through the tendons, muscular fibres, and skin on the sole of the foot, leaving the two sesa- moid bones attached to'the joint, and separates from the metatarsal bone the skin attached to its inner side. The joint is now again sought for and opened, the point of the bistoury being held vertically, and the edge a little obliquely from within outwards, and from behind forwards. As the internal ligament is divided, the knife is drawn backwards, and the undivided fibres of the upper ligament cut through, whilst the edge of the knife is directed upwards, and the point sunk obliquely at an angle of 45° in the space between the first cuneiform, and the second meta- tarsal bone. The knife, of which the point has been thrust down to the sole of the foot, is raised to a right angle, and by this movement, the fibres of the interosseous ligament are cut through, and the metatarsal bone, still a little attached, is to be completely separated and removed. If the operation be performed on the right foot, the place of the joint must be found with the fore-finger of the right hand, and the left fore-finger placed there to point it out, and whilst with the other fingers the foot is held, grasping its outer edge, the first cut is made on the inside. 2793. In exarticulation of the metatarsal bone of the little toe, the pro- ceeding is the same as in the former case. That of the little and fourth toe is performed, according to Scoutetten, by the same method as for removing the metatarsal bone of the great toe. 60* 710 EXARTICULATION OF TOES. 2794. The middle, metatarsal bones may be removed from their con- nexion with the tarsal bones, according to Scoutetten, by the oval cut, which is preferable to the method with two side cuts. In these exarticulations of the metatarsal bones, the affected tarsal bones maybe also at the same time removed. Key removed at once the outer four metatarsal bones, the second and third\;uneiform,and the cuboid bones. Dieffenbach (a) took away the outer two metatarsal and cuboid bone; and in another case, the inner two with the two cuneiform and the navicular bone. Ruyer (b) in an exarticulation of the firsrmetatarsal, removed.also the first and second cuneiform bones. V.—OF EXARTICULATION OF THE TOES. (Exarticulatio Digilorum Pedis, Lat; Exarticulation der Zehen, Germ.; Disarticu- lation des Orteils, Fr.) 2795. In exarticulation of the toes from their connexion with the meta- tarsal bones, an under, upper, or side flap, or the oval cut, may be made according to the state of the soft parts. 2796. If an under flap have to be formed, after the situation of the joint is determined, a transverse cut should be made over its upper sur- face, which divides the front and part of the side connexions of the joint. From both angles of this cut on either side of the toe a cut descends, dividing the side connexions of the joint* The toe is then pressed down- wards to dislocate it, the connexions behind are divided, the knife car- ried along the under surface of the bone, and the flap made through the side cut. After the bleeding has been stanched, the flap is brought over the surface of the wound, and kept in place with straps of plaster. In forming the flap upon the dorsal surface, a longitudinal cut is made on each side, with the knife held horizontally, beginning from the joint and continued to the junction of the first with the second phalanx. These side cuts are connected by a transverse one across the dorsal surface, and the flap separated up to the joint, into which, whilst the toe is pressed downwards, the knife is carried, and all the ligaments and soft parts cut through. 2797. If an outer or inner flap have to be formed on the great or little toe, the toe must be drawn in the opposite direction, the knife pressed on the outer or inner side, directly into the joint, carried round the joint surface of the first phalanx, whilst the toe is dislocated, and a large flap sufficient to cover the wound formed on the outer or inner side by carry- ing the knife along the bone. With the other toes, the side flaps are formed by two semilunar cuts carried from the upper part of the joint over the side of the toe which is turned down, and the first phalanx dislocated, after the flap has been turn- ed back. To prevent the protrusion of the head of the metatarsal bone in exarticulation of the great and little toes, Dupuytren saws off the head with a fine saw. 2798. In exarticulation of the second from the flrst phalanx, that which is to be removed must be bent backwards, a transverse cut made directly into the joint, and all the soft parts divided to its hind surface. The pha- lanx is now dislocated, the knife carried round the joint, and the flap made from the soft parts below sufficient to cover the wound. It is, how- (a) Hamburger Zeitschrift, vol. i. part i. ' (b) Revue Medicale, 1832; vol. iv. p. 187. EXARTICULATION OF ARM AT SHOULDER. 711 ever better when only one phalanx is to be removed, to exarticulate the whole toe, because the remaining stump is inconvenient. 2799. If all the toes have to be exarticulated at once, a semilunar cut must be made on the dorsal surface from the great to the little foe, or the contrary, through the general coverings, the joints opened and the knife carried forwards and downwards opposite to and through the crease of skin which bounds the sole of the foot in front. 2800. In exarticulation of the toes from their connexion with the me- tatarsal bones, the position of the joint having been, according to Scou- teten, ascertained by moving the toes, the point of the bistoury is to be placed a line behind the joint, and carried to the base of the toe along the crease in the skin there existing. The bistoury is now again entered from the other side into the end of the first cut, and carried upwards around the toe to the beginning of that cut. It is then passed through the whole wound to cut through whatever remains attached, and the tendons of the extensor muscles; and an assistant lifts up the plialanx, whilst the cellular tissue surrounding the joint, and the sheath of the ten- dons of the flexor muscles are divided ; the phalanx is then grasped with the fingers of the left hand, and operation completed by division of the lateral ligaments. VI.—OF EXARTICULATION OF THE ARM AT THE SHOULDER. (Exarticulatio Humeri, Lat.; Ablosung des Oberarmes aus dem Schultergelenke, Germ.; Disarticulation du Bras, Fr.) La Faye; in Memoires de l'Academie Royale de Chirurgie, vol. ii. p. 239. Le Laumier et Poyet, Thes. de Methodis amputandi Brachium in articulo. Paris, 1759. Dahl., De Amputatione Humeri in articulo. Gottingae, 1790. Plattner, Ernst, Zusatze zu seines Vaters Einleitung in die Chirurgie, vol. i. p. 432. Leipzig, 1776. Haselberg, Comment, in qua novum humerum exarticulo exstirpandi methodum, novumque ad ligaturam polyporum instrumentum proponit. Gryphiswald, 1788. Seeburg, Dissert. Exstirpatio Ossis Humeri exemplo felici probata. Viteb., 1795. Kloss, Dissert. De Amputatione Humeri ex Articulo. Gott., 1809. Schiferli ; in Hufeland's Journal, vol. xx. part iii. p. 161. Walther, above cited, p. 102. Fraser, William, Essay on the Shoulder-Joint Operation, principally deduced from anatomical observation. London, 1813. Lisfranc de St. Martin et Champesme, Nouveau Procede operatoire pour l'Am- putation du Bras dans son articulation scapulo-humerale. Paris, 1815. Emeri; in Bulletin de la Societe d'Emulation. 1815, May. De Claubry, Gualtier; in Journal de Medecine par Leroux, &c, vol. xxxii. 1815. Oberteuffer, J. G., Anatomisch-chirurgische Abhandlung von der Losung des Oberarmes aus dem Schultergelenke. Wurzburg, 1823. 8vo. Larrey, Memoire de Chirurgie Militaire, vol. ii. p. 166 ; vol. iii. p. 354; vol. iv. p. 427. Guthrie, above cited, p. 420. Klein, above cited, p. 1. Maingault, above cited. Ammon, Parallele der franzosischen und deutschen Chirurgie, p. 235. 2801. Amputation of the upper-arm at the shoulder joint is the easiest of the extirpations from the great joints. It was first performed by the elder Morand. Of the several modes recommended for performing the 712 EXARTICULATION OF ARM AT SHOULDER \ operation, the following may be considered the most important; First, the formation of an upper and under flap; Second, the formation of two side flaps; Third, the circular; and, Fourth, the oval cut. 2802. The patient either sits on a stool, or lies on a table covered with a mattress, with the side to be operated on turned to the light, and is to be properly held by assistants. The subclavian artery is to be com- pressed by an assistant standing behind the patient, either with his fingers or with a compressor (Ehrlich's) against the first rib. The pressure upon the subclavian artery by an assistant is better than the appli- cation of Dahl or Mohrenheim's compressor. When the collar-bone is considerably raised pressure upon the artery is often safer beneath the collar-bone, in the pit be- tween the edges of the m. delloides and m. pectoralis. Richerand (a) thinks compres- sion of the subclavian artery unnecessary, and only compresses the axillary artery, just before cutting through the hinder flap. 2803. The formation of an upper and an under flap, as recommended by La Faye, Richerand and others, has been very carefully laid down by Walther. The upper-arm to be removed, is brought to the side of the chest and there held by an assistant. A small amputating knife is to be thrust in, at the outermost tip of the coracoid process, up to the bone, its edge sunk along the inner edge of the deltoid muscle and carried down to its insertion, cutting through all the flesh to the bone. A second cut parallel to this is carried from the outer upper angle of the blade-bone down also to the insertion of the deltoid muscle. The two lower angles of these wounds are to be' connected by a transverse cut down to the bone. The flap described by these three cuts is now separated from the bone up to the beginning of the two side cuts, turned back and held by an assistant, who at the same time compresses the divided circumflex humeral artery, if it be not at once tied. The upper-arm is now grasped with the left hand, brought into a state of complete adduction, so that the tendons of the muscles passing from the blade-bone and hind region of the chest over the shoulder-joint to the upper-arm, and the outer side of the capsular ligament are made tense. The thumb being then placed on the head of the bone, a convex scalpel held with the whole hand cuts through with a smart stroke all the parts covering the head, which being rolled outwards and backwards, tightens the inside of the capsular liga- ment and the tendons passing over the shoulder-joint, and these are divided with repeated strokes of the knife. The arm being now brought against the trunk and raised, the head of the bone protrudes out of the joint; the whole of the amputating knife, is then passed in behind it, and cutting through the still undivided ligaments is carried, with its edge to- wards the bone, down on its hinder surface, and the under flap formed, as it cuts out obliquely downwards about four fingers' breadth below the joint; before doing which an assistant grasps the flap and compresses the artery. After stanching the bleeding and cleansing the wound, the two flaps are brought together and fastened with sticking plaster; lint and com- presses are then put upon the stump and confined with a body-bandage, the middle of which upon the shoulder has a hole in it through which the sound arm can be slipped. The earlier methods of Le Dran and Garengeot need only be mentioned as mat- [a\ Nosographie Chirurgicale, vol. iv. p. 511. Edit, of 1815. WITH UPPER AND UNDER FLAPS. 713 ters of history; the first took up the axillary artery with a straight or curved needle, two fingers' breadth below the armpit,'.then with a transverse cut three fingers' breadth below the acromion, they divided the skin and deltoid muscle, and after separating the head formed an under flap. ' 2804. According to Dupuytren (o), the arm should be raised and held at a right angle with the body. The operator placing himself on the inside of the arm, grasps and lifts up the deltoid muscle with the one hand, thrusts a double-edged knife through it from within outwards, taking care that its blade never slips from the head of the bone. The knife with its edge towards the bone is drawn downwards, and the upper flap formed by cutting obliquely outwards. The rest of the proceeding corresponds with that above described, only that the operator holds the flap before he cuts it through. Here must be mentioned Onsenoort's method. By means of a knife curved to- wards its surface, a transverse cut is made an inch and a half above the insertion of the deltoid muscle; the knife with its concavity on the bone is pushed up to the acromion, penetrates the joint, and by its concave side being drawn down upon the bone the under flap is cut off, so that by a continued stroke of the knife the two flaps are formed. 2805. Lisfranc and Champesme proceed in the following manner. The arm is brought to the side and left to itself. The operator standing in front of the shoulder drops the point of a narrow double-edged knife into the triangular space between the coracoid process and front edge of the acromion, and carries it from before to behind through the joint, so that it passes out half an inch below the part where the acromion rounds. The knife is then carried from above and before around the head of the upper-arm bone and a flap formed from the deltoid, as in Dupuytren's method. This flap being lifted up by an assistant, the capsular ligament is found opened, and the whole knife being' carried in behind the head, the lower flap is formed as after La Faye's mode. If the left arm be operated on, the knife is to be used with the left hand, or being held with the right hand, is thrust in at the back of the joint, where it has been mentioned as coming out, in the method already described, and out at the triangular space, by the coracoid process. [Astley Cooper's (b) amputation at the shoulder-joint "with a single flap," as he calls it, and which he prefers, differs little from the last-described operation, ex- cept in the flap of the deltoid muscle being made from below and up into the joint. "The subclavian artery is to be compressed upon the first rib, from above the cla- vicle, by an assistant. The ring of a common key covered with some soft linen, is a convenient instrument for this purpose. The patient should be seated on a Tow chair, and the arm to be removed should be elevated a little from the side by an as- sistant. In making the single flap, the surgeon raises the deltoid muscle with the fingers and thumb of his left hand, and introducing the catlin through the integu- ment, and under the muscle, near its insertion, he cuts upwards close to the os humeri, as far as the under part of the acromion process; the integument1 and larger part of the deltoid muscle are thus raised, so as completely to expose the outer part of the shoulder-joint; the arm being then drawn downwards, the catlin is passed into the joint, at the anterior part, so as to divide the tendon of the biceps muscle, and afterwards is carried round the head of the bone to cut through the capsular liga- ment. The separation of the limb may be completed either by passing the knife over the head of the bone, and cutting downwards to the axilla, or by placing the knife in the axilla, and dividing upwards to the joint; in either case the amputation should be finished by one stroke of the catlin." (pp. 429, 30.)] (a) Dictionnaire des Sciences Medicales, vol. i. p. 496. (b) Lectures, by Tyrrell, vol. ii. 714 EXARTICULATION OF ARM AT SHOULDER ) 2806. The elder Hesselbach's (a) method differs from those already described in forming the under flap first. The patient sits on a stool, and the operator standing before him, with his left hand grasps the upper- arm beneath the insertion of the deltoid muscle, and rolling it outwards, so as well to distinguish the coracoid process from the little tubercle on the head of the upper-arm-bone, thrusts a long, narrow, double-edged knife near the coracoid process, obliquely outwards up to the head of the bone, so as at once to open the joint; the knife then carried, with its point close on the bone, down to the lower edge of the great pectoral muscle, cuts through its tendon and that of the subscapular muscle, the acromial thoracic and anterior circumflex humeral arteries. He then rolls the head of the bone inwards, thereby rendering the hind muscles tense, and draws it as much as possible from the blade-bone, whilst at the same time he presses the lower end of the upper-arm-bone against the chest. He now carries the knife between the head of the bone and the joint-surface of the blade-bone, through the joint, thrusts, whilst he drops the handle of the knife a little, through the hinder thin part of the deltoid muscle, below the acromion, and carrying the knife down close to the bone, forms the under flap, the vessels in which being at the same time compressed by an assistant. The head of the bone is now pressed downwards, by an assistant, out of the opened capsular ligament, as the elbow is separated from the trunk, and the whole knife being placed above the head of the bone, is carried with its edge towards the bone, to the end of the first flap, and forms the upper flap. 2807. Desault (b) has given the following directions for forming an inner and an outer flap. A double edged straight amputating knife is thrust from before, into the joint, and after its point has passed on the inner side of the upper-arm, through the arm-pit, drawn down close to the bone for three fingers'breadth, and thus a flap is formed containing the vessels, which an assistant grasps, and compresses. The whole knife is then carried round the head of the upper-arm-bone, and forms a cor- responding external flap. Larrey (c) forms the outer flap first penetrating from without into the joint, and ending by the formation of the inner-flap, so that if proper as- sistance be wanting, as for instance, in the field, there may be greater safety against bleeding. Larrey (d) has more recently described his method in the following way. A longitudinal cut is made, beginning from the edge of the acromion, and carried down about an inch below the neck of the humerus, which divides the deltoid muscle into two equal halves. By the help of an assistant the skin of the arm is drawn back towards the shoulder, and two flaps, a fore and hind one, are formed by two cuts passing obliquely from within outwards and downwards, so that the tendons of the m. pectoralis and m. latissimus dorsi are included in the two cuts. There is no fear of in- juring the axillary vessels, because they lie beyond the reach the point of the knife. The cellular connexions of both flaps are now divided, and they are drawn up by an assistant, who at the same time compresses the circumflex arteries. The whole shoulder-joint is in this way laid bare, and with a third cut carried over the head of the bone, the capsular ligament and tendons are divided. The head of the bone is now moved a little outwards, and the knife carried down close to the hind surface of the bone for the purpose of completely dividing the tendinous and ligamentous connexions at this part. The assistant now places the fore-finger of both hands immediately upon (a) Oberteuffer, above cited. (c) Above cited, vol. ii. p. 170. (b) Haselberg, above cited. (d) Above cited, vol. iv. p# 427, WITH CIRCULAR, AND OVAL CUT, 715 the brachial plexus for the purpose of compressing the artery ; and the edge of the knife being turned backwards, cuts opposite the lower angle of both flaps, through the whole bundle of axillary nerves before the two fingers of the assistant. Langenbfck. (a), after drawing down and pressing the arm against the chest, makes with a small knife a cut into the deltoid muscle, so that the head of the bone may be conveniently dislocated, carries the knife behind it, and forms on the inner surface of the upper arm a sufficiently large flap, in doing which, the edge of the knife is carried down close to the bone, the head of the bone grasped and drawn towards the operator, so that the axillary artery may not be cut off too high. Dupuytren's (b) method corresponds with this. 2808. The exarticulation of the upper arm with the circular cut is variously performed. • Morand made a circular cut in the skin, drew it back, and then cut through the muscles close to the head of the bone, exposed it and divided the ligaments. Sharp proceeded in like manner, only he first laid bare the axillary artery by a longitudinal cut and tied it. Nannoni and Bertrandi first made a transverse cut three fingers' breadth below the acromion, through the skin and deltoid muscle, and drawing them back cut into the capsular ligament, dislocated the head of the bone, and after tying the axillary artery, cut through the armpit (1). Alanson made a circular cut a hand's breadth below the acromion, through the skin, and with the edge of the knife directed obliquely upwards, through the muscles, and afterwards, for the more easy division of the joint, he made a straight cut through the upper part of the deltoid muscle. Graefe (c) lays down the following rules for his funnel-shaped cut (Trickierschnitt.) The arm being held nearly horizontally, the cut through the skin is madethree fingers' breadth below the acromion, and then the cut through the muscles with his leaf-knife, pressed obliquely upwards to the head of the bone. An assistant draws the muscular mass upwards with both hands, and then, the head being rolled forwards and upwards, the capsular ligament is opened, first, on the fore and upper, and after- wards, upon the upper and back part of the head with the leaf-knife, held obliquely; the tendon of the m. biceps is cut through, the arm drawn by the operator towards himself, and the head being thereby dislocated, the under hinder part of the capsular ligament is divided. The vein is to be also tied, and the wound brought together in a vertical direction with one suture. (1) Cornuau and Sanson's method agrees precisely with this, only that the former makes the semicular cut through the deltoid muscle, of four fingers' breadth, and the latter only a finger's breadth below the acromion. Velpeau's (d) method is the same. Benj. Bell's (e) operation consists in one circular cut at the point of the deltoid muscle through the skin, and a second through the muscles, and tying the artery; then two longitudinal cuts, in front from the acromion and behind from the top of the shoulder,"run down into the circular cut, after which the flaps thus formed are separated from the bone and its head set free. 2809. In exarticulation of the upper-arm with the oval cut, Scoutet- ten (f) proceeds in the following manner:—The operator, having satis- (a) Bibliothek fur die Chirurgie, vol. iv. (d) Medecine Operatoire, vol. i. p. 39. p 5Q5. (e) Above cited, vol. vi. p. 417. (6) Lecons Orales, vol. iii. p. 328. (0 Above cited, p. 15, pi. i. and ii. (c) Above cited, p. 110, pi. ii. and iii. 716 EXARTICULATION OF ARM AT SHOULDER.' tied himself of the situation of the acromion, grasps, if operating on the left arm, the middle of the upper-arm with the left hand, brings it about four or five fingers' breadth away from the trunk, and thrusts a pointed knife, immediately below the acromion, up to the head of the humerus. The edge of the knife is now sunk deeply, carried downwards and in- wards, and thus the first cut is completed, which stretches down four fingers' breadth from the acromion, and upon the bone divides the hind third of the deltoid muscle, and the greater part of the fibres of the long head of the m. triceps. The operator now places the knife, with its point downwards, on the inside of the arm, and beginning the second cut upon the other side of the m. triceps, at the same height as the end of the first cut carries it inwards and upwards to the acromion where it meets with the former. In order to lay bare the joint better, that part of the deltoid muscle attached to the humerus maybe a little separated, and the edges of the wound drawn apart by an assistant. The upper-arm is now to be moved about in different directions, and the tendons and cap- sular ligament, being divided together, the head of the bone is lifted out of the joint, and the arm being pressed towards the body, the whole knife is carried round it close to the bone, the humeral artery compressed in the wound by an assistant, and the still undivided parts, containing the vessels, cut through. When the right arm is operated on, the first cut must be made from the inside of the joint up to the acromion, but in other respects, the ope- ration is the same. In like manner Dupuytren and Beclard proceed. They form from the middle of the top of the shoulder two semilunar cuts running downwards, and ending be- fore the plexus. The flaps thus formed are turned back, the joint opened, the knife carried behind the head downwards, and the flap containing the vessels, which are compressed by an assistant, divided. Bonfils (a) begins his first cut between the coracoid process and the acromion, and the *scond, not in the beginning of the former, but two inches lower, so as to form a larger hinder flap, with which the joint-surface can be better covered. Blasius's oblique cut may also here.be mentioned. 2810. As regards the choice of the above-mentioned methods for ex% articulating the upper-arm-bone, the following circumstances must^be attended to. It must here be considered, as in every other exarticula- tion, in what way the soft parts are injured, whether the bone be broken, and whether the arm be more or less moveable. The method^of opera- tion must be directed by these circumstances, and the formation of the flaps undertaken in such way as the condition of the soft parts allows, and, as is necessary to cover the wound properly. The modification of La Faye's method by Wa£ther and Dupuytren is, in general, most fit- ting ; at least, in certainty and readiness of execution it surpasses all other. The objection of the more tedious and difficult healing, on ac- count of the flaps, the base of which corresponds to the greater diameter of the joint, not fitting well; on account of the obstacle to the escape of the pus, and so on is contradicted as well by my own experience as by that of others, and is no reason for preferring the. vertical wound with an outer and inner flap. The quickness in performing Lisfranc's and Hesselbach's operations is not, indeed to be denied; but in living persons where the parts about (a) Journal de Medecine, vol. xcvi. p. 192. 1826. EXARTICULATION OF ARM AT SHOULDER. 717 the joint are often swollen and variously altered, the arm little or not at all moveable, and the head of the upper-arm-bone firmly drawn into the socket by the contraction of the muscles, this method is, for beginners especially, in most cases unsafe. The point of the knife is easily caught, must be carried inwards and forwards in various ways, and the like. Beginners find out that here, as in many other of the modes of exarticu- lation proposed in modern times, sleights of hand, which are readily per- formed upon the dead body, are unavailable in cases of necessity. Lan- genbeck {a) has already justly objected to Graefe's method, that the knife with its edge turned outwards is not fit to be rolled about, and, especially in the extended position of the arm, that the much-stretched axillary artery would be cut through too near the shoulder-joint, and might retract so greatly as to cause great difficulty in tying it. 2811. When, after exarticulation of the upper-arm-bone, the acromion or the glenoid cavity is in any way injured, so that its removal may be considered necessary, it is easily done with the saw (&)._ Brown sawed off the projecting acromion, for the purpose of making an insufficient quantity of skin better cover the wound. Robinson (c) recommends removal of the acromion and the glenoid cavity, so that the stump may be made rounder and more, regular. Fraser {d) also proposes the removal of a portion of the acromion and coracoid process, together with the whole glenoid cavity, because they hinder the quick union of the parts by the adhesive inflammation (1). Supported by the law of the formation of the bone, in consequence of which the top of the acromion remains cartilaginous to the age of from eleven to fifteen years, Lisfranc (e) recommends, for persons of this age, the following practice:—Be the position of the arm what it may, ' the operator places the heel of the amputating knife upon the outer side of the top of the coracoid process, and carried it up to the hind edge of the arm-pit. The flap thus formed is lifted up, the cartilage of the acro- mion and collar-bone cut into, the joint readily entered, and the under flap formed in the usual way. • When the upper-arm bone has been shot through by a ball close under its head, the, appearance of the wound does not point out its importance, as the shoulder re- tains'its form; and it can only be ascertained, when the arm-bone is examined throughout its whole length with the fingers, when a deep pit is found, which points out the solution of continuity. Enlargement of the shot wound is insufficient for the removal of the head of the bone, and if it be left it causes inflammation, sup- puration, and destruction of the bone, which render the exarticulation of the arm necessary. In such cases these symptoms must be guarded against, by the early removal of the head of the bone, or of the broken pieces. Larrey (/) made a cut in the middle of the deltoid muscle, parallel to its fibres, carried it down as far as possible, divided the edges of the wound on the sides, so that he laid bare the joint of which the capsular ligament is generally opened. With a curved, blunt-pointed bistoury the insertions of the m. supra-spinatusy infraspinatus, teres minor, subscapu- lars, and the long head of the m. biceps were divided, the head of the bone freed and removed with the fingers. The arm was then brought up to the shoulder, and kept in that position by proper bandages and a sling. Either anchylosis between the arm and shoulder-blade, or an artificial joint, which permits certain motions, is the result. (a) Above cited, p. 504. {d) Above cited. (b) Faur ; in Memoires de l'Academie de (<•) Averill, above cited, p. ISO. Edit. Chirurgie, vol. ii. p. 463. of 1823. (c) New England Journal, vol. iii. Bos- (/) Memoires de Chirurgie Militaire, vol. ton, 1814. ii. p. 173. Vol. hi.—61 718 EXARTICULATION OF FORE-ARM AT ELBOW. Guthrie (a) says that " a wound from a musket-ball, causing a fracture beneath and exterior to the capsular ligament, although in its immediate vicinity, by no means demands amputation, from this cause alone. With a wound from a musket- ball passing through the soft parts and the bone, in the same situation, without de- stroying its substance to any great extent, the arm has frequently been preserved." [(1) Unless disease of the acromion, glenoid cavity, or coracoid process, impera- tively require their removal, when amputation at the shoulder-joint is performed, or when by accident the skin is not of sufficient length to cover the joint, the proposal of removing these processes, or either of them, is not to be entertained; no real ad- vantage is to be gained from it; and if it be believed, that the continuance of the car- tilage upon the glenoid cavity offer any bar to union in the ordinary time, which, so far as my own personal experience, and the observations I have made in the practice of others, is certainly not proved, the surgeon may scrape off the cartilage, if he have a fancy to do so, but it is matter of no consequence at all. Amputations at the shoulder-joint are not very frequently needed, as it appears from Liston's reported cases, he had but one in University College Hospital during five years, and myself only one in six years at St. Thomas's, both secondary to ac- cident, and both recovered. Astley Cooper says :—" In every instance in which I have performed the amputation through this joint, and every case in which I have seen it done, the recovery of the patient has been speedy and perfect." (p. 432.)] Amputation through Shoulder-Joint. Accident or Disease. Operated on. Remarks. Dis-charged. 1840 John Bateman, aged 39 (coal-car-man,) admitted July 25. Compound fracture, with comminution and small wound in skin, but not much bruising; conse-quent on cart-wheel passing upon, but.not over the arm. On the fourth day irritative fever set in; the whole arm much swollen. On the sixth day some bloody oozing, which continued through the day, and reduced him much. Bleeding came on again on morning of twelfth day, to the amount of six ounces; said to have been in a jet, but seemed to me to be venous; but it brought him very low. Was easily checked by pressure; and when he was revived by stimu-lants,the operation was performed. Aug. 6. Twelve days after. With flaps of m. deltoides by piercing from*efore. The artery held as the second cut was being made. Six arteries tied, and three hours after two more. The flap was dropped down, and covered with a wet cold cloth. He became very restless soon after the operation, and so con-tinued for nine hours, till the opium given sent him to sleep. At twenty-two hours the fla p was 1 igbtly applied with straps of plaster. Went on very steadily improving; but the discharge from the wound was very profuse. Nov. 10. VII— OF EXARTICULATION OF THE FORE-ARM AT THE ELBOW. (Exarticulatio Antebrachii, Lat.; Ablosung des Vordernarmes in Ellenbogengelenke, Germ.; Disarticulation de VAvant Bras, Fr.) Brashor, above cited. Moublet ; in Journal de Medecine, vol. xi. p. 240. Mann; in New York Medical Repository, vol. vii. 1821. Textor; in Neuer Chiron, vol. i. part. i. Dupuytren; in Sabatier Medecine Operatoire, vol iv. p. 524. New Edition. Rodgers; in New York Medical and Physical Journal, vol. vii. p. 85. 2812. This operation, first performed by Pare, and more fully deter- (a) Above cited, p. 424. EXARTICULATION OF FORE-ARM AT ELBOW. 719 mined by Brasdor, is objected to by nearly all writers, and amputation through the lower third of the fore-arm is preferred to it. Mann, Textor, Dupuytren, and others have, however, performed it success- fully. 2813. The operation is best performed according to Textor's direc- tions :—After making provision against the bleeding during the operation, and the arm being straightened, a long double-edged amputating-knife is passed in at the top of the outer condyle of the upper-arm-bone, carried flat before the bend of the elbow, and thrust through before and above the inner condyle, at corresponding height to the point of entrance, and then being drawn down, a flap is formed of three or four fingers' breadth long. The vessels found in this flap may be at once tied. A cut through the skin is next made on the opposite side of the arm, two fingers' breadth below the entrance of the former, extending from one end of the exist- ing wound to the other, and the skin is dissected back to set the ole- cranon free. The external ligament is now cut through, the knife carried between the upper-arm-bone and the radius, and the fore-arm being bent, cuts through the tendon of the m. triceps, and lastly, the internal lateral ligament. According to Brasoor, a transverse cut should be made through the skin and tendon of the m. triceps on the extending side of the arm; the ligaments are then divided, and the whole knife, the arm being bent, is carried through the joint, and forms from the inside of the arm a fleshy flap. Jaeger favours this method. The fore-arm being bent at a right or an oblique angle, he makes a semicircular cut through the skin with a small convex amputating- knife, two fingers' breadth below the point of the olecranon, from the head of the radius, to the outer edge of the ulna. The skin is drawn back by an assistant above the olecranon, and the tendon of the m. triceps cut through, by which the joint is opened. Whilst the fore-arm is bent still more, the lateral ligaments between the up- per-arm-bone and the olecranon and the ulna and radius are opened, the knife is carried over the coronoid process upon the front of both bones, the arm being slightly bent, and by cutting from within outwards, a flap of three fingers' breadth is formed, which the assistant grasps before its complete division, and compresses the brachial artery. Hager makes two longitudinal cuts of three inches length, down from the con- dyles to the ulna and radius, by which he marks out the front flap. An inch below the upper angle he makes a semicircular cut through the skin and muscles behindr separates the little flap upwards, passes into the joint from behind, and forms the front flap, two inches or two inches and a half long. Rodger forms the front flap with a semicircular cut, from the head of the radius to the- inner condyle, and by separating the skin he forms the hind flap. After which the joint is cut through. Dupuytren's (a) agreed with Textor's method, except that he sawed off the ole- cranon. He performed this operation eight or ten times successfully, and preferred it as giving a greater length of the upper-arm, and leaving the m. triceps attached, by sawing off the olecranon. When the soft parts are not sufficient to form a front flap, Dupuytren made a circular cut through the skin and aponeurosis, the fore-arm being half bent, three fingers' breadth below the condyles of the upper-arm-bone. These parts are drawn back by an assistant, and the muscles cut through at their edge down to the bone. Whilst the operator separates them upwards from the bones, he reaches the joint, which is opened by dividing the lateral ligaments and the capsular ligament on the front. The knife then easily passes between the bones and the operation is completed. Velpeau and Cornuau proceed in like manner with the circular cut, only they do not saw through but exarticulate the olecranon. Textor (b) proposes the oval cut, which however, is more difficult and not so advantageous as the flap, in the following way. The arm being brought horizontal, (a)* Lecons Orales, vol. iii. p. 318. (b) Jaeger, above cited, p. 365. 720 EXARTICULATION OF HAND AT THE WRIST. the fore-arm straightened, and the hand prone, the surgeon standing on the outer side makes, with a small amputating knife, onecutabout four inches long and pene- trating to the bone, from the head of the radius obliquely upwards and inwards to above the tip of the olecranon, and then a second on the ulnar side from the upper end of the ulna, to the same height. He then dissects back the flaps to their base, passes between the upper-arm-bone and radius, upon and around the olecranon, and cuts through the tendon of the m. triceps, whilst the fore-arm is bent and supine. He now cuts forwards and downwards over the coronoid process of the ulna, above the head of the radius and along both bones so far upwards as necessary to form a flap three fingers' breadth long. The wound is brought together lengthways. Baudens proceeds in another way. The fore-arm being rendered supine and the brachial artery compressed, the surgeon, standing on the inner side if he operate on the left, and on the outer if upon the right arm, marks with varnish an oval, which begins on the outer edge of the radius four fingers' breadth below the bend of the elbow, and terminates on the hind edge of the ulna three fingers' breadth below the bend of the arm. Following this mark he cuts through the skin, which, by dividing its connexions and drawing back with his left hand, he separates to the extent of eighteen lines. He then cuts through the muscles down to the bone, holds back the fleshy parts like a ball and divides the deep muscles circularly, at the same time passing between the joint surfaces of the upper-arm bone and radius, and com- pletes the exarticulation by division of the ligaments, and of the tendon of the m. triceps near the tip of the olecranon. The soft parts by their own weight drop over the joint surfaces and form a hollow globe in the point of which the joint surface of the humerus is found. After tying the vessels the wound is brought together lengthways. VIII.—OF EXARTICULATION OF THE HAND AT THE WRIST. (Exarticulatio Manus, Lat.; Ablosung der Hand^ Germ.; Disarticulation du Poignet, Fr.) 2814. The brachial artery is to be compressed with the tourniquet; one assistant holds the fore-arm and draws the skin back, a second holds die hand. The operator, standing on the inner side for the left, and on the outer for the right hand, makes a circular cut. through the skin half an inch from the spinous process of the radius. The skin is next dis- sected up, without the tendons, to the wrist, turned inside out, and held by the assistant. The hand is now put between pronation and supina- tion, the knife placed before the spinous process of the radius, and whilst the hand is pressed down, the whole knife is carried into the joint, ob- liquely towards the ulna, and divides all the ligaments and tendons. The edges of the wound, after tying the vessels, are brought together in the oblong direction of the joint. Instead of the semicircular cut, a flap maybe made upon the back and front of the wrist. It may be necessary on account of some peculiar kind of accident which af- fects the exarticulation to form a large upper or under flap; for this purpose the skin of the thumb and the like may Tie saved. The above-described mode of proceeding is better than by dividing the skin and tendons on the back of the hand by a semicircular cut to pass into the joint, and drawing down the knife to form a flap on the front of the hand. Or, according to Lisfranc, the hand being held between pronation and supination, a narrow knife is thrust through the soft parts opposite the joint on the palmar surface from one side to the other, and then being drawn down forms a flap ; after which a semicircular cut is made through the skin upon the dorsal surfaces the flap turned back and the joint divided from the radius. [If amputation through the wrist-joint be performed with flaps, special care must be taken to avoid, in forming the front flap, the pisiform bone, which often catches the knife, and unless well cleared, spoils the edge of the skin-cut.—j. f. s.] [ 721 ] IX—OF EXARTICULATION OF THE METACARPAL BONES AT THEIR JUNCTION WITH THE CARPUS. (Exarticulatio inter Carpum et Metacarpum, Lat.; Ablosung der Mittelhandknochen aus ihren Gelenken mit der Handwurzel, Germ.; Disarticulation des Mita- carpiens, Fr.) 2815. The exarticulation of the metacarpal bone of the thumb, of the fore- and of the little-finger, and of all the fore-fingers together, the thumb being still preserved, is now to be considered. The exarticulation of the middle and ring metacarpal bones is not to be recommended. The dis- ease being rarely confined to any one of these bones, the operation is attended with much difficulty. Collections of pus take place in the car- pal joints, and the exarticulation of the hand afterwards becomes neces- sary, as I have seen in two cases. It is better therefore under such cir- cumstances, to amputate through the continuity of the metacarpal bones of the middle and ring-fingers. 2816. In exarticulating the metacarpal bone of the thumb, if the soft parts permit the formation of a side flap, it must be thus performed. An assistant, who holds the fore-arm, compresses the radial and ulnar arte- ries. The operator holding the thumb with one hand abducts it strongly, so as to render the fold of skin between it and4he fore-finger tense. He now carries a straight bistoury in this fold to the connexion of the first phalanx of the thumb with its metacarpal bone, and along the side of the metacarpal bone to the joint. The thumb is now violently abducted to stretch the ligaments, the whole knife carried into the joint, the metacar- pal bone dislocated, the knife carried up on the other side of the bone, and along it, to its junction with the first phalanx, where, by cutting ob- liquely out, the flap is formed, which corresponds precisely to the first cut. After tying the vessels the flap is properly applied and fastened with strips of sticking plaster, and a bandage. Where the formation of a side flap is not possible, and only an upper or under flap can be formed, the same mode must be employed as de- scribed in exarticulation of the metatarsal bone of the great toe. 2817. In precisely the same way may the metacarpal bones of the ring- and little-fingers be separated from their connexion with the carpus, only that these exarticulations are more difficult than that of the thumb. 2818. Langenbeck's method of shelling out the bone from the soft parts by carrying forwards a £ shaped cut from the junction of the me- tacarpal bone of the thumb with the trapezium, and then cutting through the joint, is more troublesome and tedious than that described. Scoutetten (a) has also applied his method to the metacarpal bone of the fore-finger, of the ring- and of the little-finger, according to the rules given for exarticulation of the metatarsal bones. 2819. The oval cut of Scoutetten is most convenient for exarticula- tion of the middle metacarpal bone. The knife is placed at the joint, above the bone at the crease of the finger in front, and carried round cor- respondently to the first phalanx; then placed on the other side in this cut, and carried back, and in the same direction as the first cut to its be- ginning. The soft parts are separated by short strokes from the bone to (a) Above cited, pi. iii. iv. v. 61* 722 EXARTICULATION OF THE METACARPAL BONES, &C. the joint, which is best entered on the under side. The wound is united by bringing the neighbouring metacarpal bones together. The practice of making two side cuts in the interspace united on the dorsal, and palmar surfaces by an oblique or A shaped cut, keeping close to the bone to be removed, and avoiding the extensor tendons of the next fingers is inconvenient. The extensor tendon of the finger to be removed is di- vided with the point of the knife, the metacarpal bone pressed down, and the connexions of the joint cut through. If both middle metacarpal bones are to be exarticulated, the fore- and little-finger being well adducted, one cut between the bones is to be made close on the radial side of the middle finger, and another on the ulnar side of the ring-finger to the carpus. These two long cuts are then to be con- nected on the volar and dorsal surfaces by transverse cuts close down to the bone, the soft parts turned back and the joint cut through. After the bleeding is stanched the flaps are to be brought together (1). The exar- ticulation of the last two or three metacarpal bones may be performed in like manner; the cut between the bones being first made, and then a lon- gitudinal cut along the ulnar side of the fifth metacarpal, both these con- nected by a transverse cut on,the back of the hand nearer or farther from the carpus, the soft parts dissected back, the joint divided and the volar flap made (2). * (1) von Walther (a) proceeds in the same way in extirpation of the middle and ring-finger, together with removal of the hind part of the metacarpal bone of the fore-finger. Astley Cooper (b) also operated successfully in the same way. (2) Riadore, Guthrie, von Graefe, von Walther, and Jaeger have removed in this manner the last two, and Astley Cooper the outer three and the first meta- carpal bone with the thumb, so that the fore-6nger alone remained, and served as a very useful hook. Larrey and Riadore removed the second, third, and fourth metacarpal bones, preserving the thumb; and Tyrrell took away successfully the fourth and fifth metacarpal bones with the pisiform and unciform bones, and the half of the first, second, and third metacarpal bones. Benaben (c) extirpated, instead of the whole hand, the first and second metacarpal bones, the scaphoid, great, and trapezial bones, and cut off the upper part of the third metacarpal bone, preserving the outer three fingers. 2820. In exarticulation of the four metacarpal bones, but preserving the thumb, a double-edged knife is passed in, whilst the hand is supine, on the ulnar side, at the junction of the metacarpal bone of the little finger, thrust between the other metacarpal bones and the soft parts of the palm to the junction of the metacarpal bone of the fore-finger, where it is thrust out, whilst the thumb is abducted. By cutting obliquely outwards a flap is formed; then a semicircular cut is made on the back of the hand, through the skin and tendons, and the joints opened on the palmar sur- face of the hand. After tying the vessels, the flap is brought over the wound and fastened {d). Troccon {e) makes first the cut on the back of the hand, cuts through the joint, beginning on the radial or ulnar side, and forms a palmar flap, whilst the knife is carried into the opened joint and drawn forwards and downwards. (a) Journal fur Chirurgie und Augenheil- (d) Maingault, above cttcd, pi. ii.—Cht- kunde, voL xi>i. p. 352. rurg. Kupfertaf., pi. lixiii.— Gensoul; in (b) Lectures onSurgery, by Tyrrell, vol. Revue Medicale. 1827; vol. ii. p. 143. ii, p. 423. (e) Nouvelle Methode pour l'Amputation (C) Revue Medicale. 1825; vol. i. p. 371. du Poignet, dans son Articulation carpo- March.—Jaeger, above cited, p. 334. metacarpienne, Bourg, 1926. EXARTICULATION OF THE FINGERS, &C. 723 When the disease is confined to merely one or other metacarpal or metatarsal bone, it is very advantageous, according to Blandin (a), to remove.that one alone, and to preserve all the others ; with which opinion Jaeger also agrees. In removing the first metacarpal bone, the hand is placed on its ulnar edge upon a table, and held firmly by an assistant, who grasps on the one side the thumb, and on the other the four-fingers. The operator makes, along the muscles of the thenar eminence, a cut four fingers' breadth long, which must extend a little beyond the carpal and finger-joint of the first metacarpal bone. The edges of the wound are drawn asunder, and the attachments of the m. opponens pollicis and of the first m. interosseus are cut through. During the latter act the knife rests close above the first metacarpal bone, so as not to wound the radial artery, which lies close to the second bone. The tendons of the flexor and extensor muscles of the thumb are drawn back, the tendon of the great m. abductor pollicis cut through at its insertion, and thecarpo-metacarpal joint of the thumb divided from without inwards; after which the bone is lifted out with strong forceps, and separated from all the fibrous parts which connect the metacarpal bone to the undermost phalanx. In removing the other bones the method is the same, with but little variation. In removing the second metacarpal bone, wounding the radial artery is unavoidable. As to the rest, the part of the inner transverse ligament of the metacarpus, corres- ponding to the phalanx, must be left, the joint must be opened from behind forwards, and when this is half done, and the bone half dislocated, the knife must be lifted up before the head of the metacarpal bone, for the purpose of cutting through the ante- rior ligament from above, so that it remains attached to the phalanx, together with the transverse metacarpal ligament with which it is connected. In extirpating the first metatarsal bone, the foot must be so placed as to rest on its outer edge; the operator then thrusts a long narrow bistoury on the inner side of the m. extensor longus pollicis, so that its point may come out at the inside of the tendon of the m. flexor pollicis, and then cuts out a flap, the base of which corresponds to the hind joint of the metatarsal bone, and its tip to the front joint of that bone ; the rest of the operation is performed as on the metacarpus. X.—OF EXARTICULATION OF THE FINGERS, AT THEIR JUNCTION WITH THE METACARPAL BONES, AND AT THEIR OWN JOINTS. (Exarticulatio Digitorum Manus, Lat. ; Ablosung der Fingerglieder aus ihrer Verbin- dung mit den Mittelhandknochen, unduntersich, Germ.; Desarliculationdes Doigts, Fr.) 2821. All that has been said in regard to exarticulation of the toes from the metatarsal bones, applies to amputation of the fingers at their junction with the metacarpus. In exarticulation of the middle and ring-fingers, Dupuytren (b) cuts off the head of the metacarpal bone obliquely with a saw. In younger persons, in whom ossifica- tion is incomplete, the head of the bone may, according to Lisfranc, be cut off with a knife. Barthelemy (c) thinks that inflammation, gangrene, and suppuration occur after exarticulation of the fingers from the metacarpal bones, in consequence of the strangu- lation of the underlying cellular tissue by the palmar aponeurosis, and therefore pro- poses, after extirpating the finger, to separate the processes of the aponeurosis, which is easily done ; and by which, whilst the tension of the aponeurosis is got rid of, these bad symptoms are more certainly prevented. 2822. In exarticulation of the joints of the fingers, from each other, if the state of the parts permit, the following is the best mode of proceed- ing:—-An assistant draws out the diseased finger from the healthy fingers, held in a state of pronation, and holds them firmly. The operator, with his left thumb and finger, grasps the diseased joint and bends it, whilst (a) Gazette Medicale de Paris, vol. ii. p. 152; 1831. (6) Sabatier, above cited, p. 534. (c) Journal Universel des Sciences Medicales. 1829; p. 211. 724 IMMEDIATE AMPUTATION. with the other hand he carries a straight narrow bistoury, holding it as in making a longitudinal cut, a line below the projection which Is formed by the head of the upper phalaltx, in a horizontal direction from the left to the right side, with a stroke into the joint. The lateral ligaments are then divided, the diseased phalanx pressed much downwards, the blade of the knife carried to the palmar surface, forwards, and close to the bone, where by cutting obliquely a flap is formed. If two flaps have to be formed, a semilunar cut is to be made on the dorsal surface of the joint, the skin drawn back, the joint cut into, and the lower flap formed as in the former case. This mode of proceeding is, however, unsatisfactory, because the upper flap is very thin, its dis- section painful, and after the cure the scar is in the middle, and thus most exposed to external violence. Less suitable is Lisfranc's (a) method of forming the flap, by thrusting the knife through the palmar surface, cutting into the joint frorrrabove downwards, and through the skin on the dorsal surface. For the purpose of producing, by adhesion of the tendon of the flexor muscle, the mobility of the firstphalanx, after the removal of the second, Lisfranc (b) previously makes a longitudinal cut of half an inch on the palmar surface, which wounds the tendon, the wound heals by suppuration, and then the extirpation is performed. This practice is objectionable, because thereby inflammation of the sheath of the tendon may be set up; it is also unnecessary, because the tendon unites with the scar (c). [I take the opportunity, in concluding the subject of amputation through the shaft or in the continuity of bone, and through the joint or in the contiguity of bone, to add Liston's cases to my own for the purpose of making a better average of the re- coveries and deaths after the operation for amputation. Of Liston's cases - - 52 Recoveries - - 45 Deaths - - 7 Of my own cases - - 54 - - 42 - - 12 106 87 19—106 Making a per eentage of 82.075 recoveries, and 17.925 deaths to the whole number of cases operated upon. IMMEDIATE AMPUTATION. The question of Immediate Amputation has been already discussed (d) in treating of compound fracture, and to this the reader will refer. From the reports of the amputations which I have given, it is proved, as I there stated, that primary ampu- tation is more serious in its effect on the constitution, when performed on the lower than on the upper limbs, and more especially when the thigh is the part of the member subjected to that operation. If, however, a much-injured thigh be not at once removed, the patient almost invariably has a fearful struggle with irritative or with hectic fever, if he escape the former, but more commonly he has to pass through both, and dies in consequence of his powers being completely worn out. The sur- geon is therefore placed in a most difficult situation in determining whether he shall amputate the thigh, or through it at once. The danger to the patient is great if the operation be performed, as my reports prove; the danger is as great and the patient's sufferings severe, protracted, and without good result, if the operation be not per- (a) Memoire sur un Nouveau Precede pour pour pratiquer l'Amputation dans les Articu- 1'Amputation dans les Articulations des lations du Metatarse et du Metacarpe avec Phalanges; in Revue Medicale. 1823; vol. les phalanges; in Revue Medicale. 1823; i- P- 233. vol. i. p. 382. (b) Ibid., above cited, p. 236. {d) Vol i. p. 569-74,par. 590, note. (c) Memoires sur de nouvelles Methodes IMMEDIATE AMPUTATION. 725 formed, as I have witnessed again and again. On the whole, I am inclined to believe that primary amputation of or through the thigh, is to be preferred. But with regard to the leg, the danger is very much less, and in the several parts of the upper limbs, comparatively trivial, and therefore, according to my experience, amputation in these cases should not be deferred. John Hunter indeed thought differently, and preferred secondary amputation in case of accidents; and his opinion is too important to be passed by unnoticed. He says (a) :—" If a man gets a very bad compound fracture in the leg, or has his leg taken off, either for this fracture, or in consequence of any other accident, he stands a much worse chance of recovery than one who has been accustomed to a local dis- ease ; even the man with the compound fracture will do much better, if his leg is not taken off till the first symptoms are over; or at least we may be certain that the symptoms arising from the amputation will not be nearly so great as those that arise at first from the fracture, or would have arisen from the immediate amputation. * * * For, first, I do not look upon full health as the best condition to resist disease; disease is a state of body which requires a medium. Health brooks disease ill, and full health is often above par; persons in full health are too often at the full stretch of action, and cannot bear an increase, especially when diseased ; and, as I have before observed, it is a new impression on the constitution, and till it be in some degree accustomed to local disease, it is less able to bear such as is violent; besides the removal of a diseased part which the constitution has been accustomed to, and which is rather fretting the constitution, is adding less violence than the removal of a sound part in perfect harmony with the constitution." (p. 233.) Notwithstanding Hunter's great authority, however, I must still agree with Astley Cooper (b), that "if it will be necessary to amputate in a few days after the accident, then the sooner it is done the better. * * * For if you amputate immediately, the constitution has but one shock to sustain, and in general rallies much better than when the amputation is delayed." (p. 680).—j. f. s. Rutherford Alcock, in his very able Lectures (c), which I regret my limits have not permitted me to make use of; but which are of such deep interest and im- portance that I would recommend them for careful perusal, and specially to Army and Navy Surgeons, as they are more particularly concerned with the cases which form the principal subject of his consideration, observes :—" That the injuries of civil life, and the amputations for them, especially those performed in the primary period, are followed by more unfavourable results than equally grave injuries occurring in the field. If we reflect for a moment upon the mode in which the two classes of injuries are inflicted, I think an adequate reason will suggest itself. A man em- ployed in some agricultural or manufacturing occupation, if he becomes the subject of a grave injury, it must be under circumstances for which his mind is totally un- prepared, under circumstances the most calculated to cause terror and a great shock, mental and physical. * * * In military life, the injuries inflicted are under very different circumstances; it is true, men but the moment before with sound limbs and in full health, fall with bones crushed and broken, with limbs torn from their bodies. But every man goes into action knowing his liability to such occurrences; he sees his comrades fall on every side; many he sees besr it almost gaily—the majority with good courage; he has known hundreds to whom the same lot has fallen, recover, and either return to their duty or pass the rest of their lives, not un- happily with a pension. He is excited at the moment; the onward rush, the shouts of the victors and the vanquished mingling with the roar of artillery, the flashing peals of musketry, all tend to make him reckless of any feeling but one of wild ex- citement or enthusiasm. * * * The immediate shock of the injury is often, therefore, trifling in some of the worst injuries." (pp. 850, 51, vol. ii.)] (a) On inflammation, &c. nature, progress, and terminations of the (b) Lectures. Injuries for which it is required ; in Lancet (c) Lectures on Amputation, and on the 1840-41; vol. i. and ii. [ 726 ] Fifth Section.—OF EXCISION OF THE JOINTS (a). (Excisio Arliculorum, Lat.; Ausrottung der Gelenklheile der Knochen, Germ.; Resection des Extrimitis Articulaires des Os, Fr. White, Charles, Cases in Surgery, &c, p. 1. London, 1770. 8vo. Sabatier, Seances Publiques de l'Academie de Chirurgie, p. 73. Paris, 1799. ---------— Memoires de l'Institut National, vol. v. p. 366. 1805. Park, H., an Account of a New Method of treating Diseases of the Joints of the Knee and Elbow. London, 1733. 8vo. Moreau, Observations pratiques relatives & la Resection des Articulations affectees de Carie. (Diss. Inaug.) Paris, an xi. (1803.) Park, H., and Moreau, Cases of the Excision of Carious Joints; with Observa- tions by J. Jeffray. Glasgow, 1806. Chaussier ; in Magasin Encyclopedique, cinquieme annee. Wachter, Dissert, de Articulis exstirpandis, inprimis de Genu exstirpato. Gron- ing., 1810. Roux, De la Resection ou de Retranchement de portions d'Os Malades, soit dans les Articulations, soit hors des Articulations. Paris, 1812. Syme, James, On Excision of Joints; in Edinburgh Medical and Surgical Journal, vol. xxxi. p. 256. 1829. ------------, A Treatise on the Excision of Diseased Joints. Edinburgh, 1831. 8vo. Crampton, Philip, On the Excision of Carious Joints ; in Dublin Hospital Re- ports, vol. iv. p. 185. 1827. Jaeger, M., Article Decapitato; in Rust's Handbuch der Chirurgie, vol. v. p. 559. ----------, Operatio Resectionis conspectu chronologico adumbrata. Erlang., 1832. Meyer, G., Ueber Resection und Decapitation. Erlangen, 1829. 2823. Although Paultjs .ZEgineta and Heister had previously pointed to the extirpation of diseased joints, yet was it only first performed by Filkin of Liverpool, on the knee-joint, in 1762, and the removal of the head of the shoulder-bone was undertaken by Vigaroux, David and C. White (1), alout the same time. The successful result which White, and afterwards Bent (b) and Orred (c), had of this operation led to its further extension to other joints. Park applied it to the knee-and pro- posed it for the elbow-joint. Moreau, father and son, performed it on the latter, and at the ankle and wrist-joint; White, and afterwards Mulder (2), pxoposed it for the head of the thigh-bone; von Graefe {d) undertook it at the jaw-joint, and Davie {e) on the collar-bone* It was subjected to the closest examination by Sabatier, Percy (f), Roux, Moreau the son, Larrey {g), and Guthrie (h), and much valuable ex- perience in reference to it has been published. But the many and favourable results obtained by the English and German Surgeons, Syme, Textor, and Jaeger, have contributed to extend the employment of this practice and by their successful issue have contradicted many of the ob- jections to it. (a) I have here slightly deviated from (d) Bericht iiber das Klinisch-chirurgisch Chelius, distinguishing Excision from Re- Institut. 1821. section, and placing them in two distinct (e) Cooper, Astley, Lectures on Surgery, sections; to which they seem to me as fully by Tyrrell, vol. iii. p. 297. entitled as Exarticulation and Amputation, (/) Eloge historique de M. Sabatier. and for the same reasons.—j. f. s. (g) Memories de Chirurgie Militaire, vol. (6) Philosophical Transactions, vol. lxiv. p. ii. p. 171. 353. 1774. (JK Above cited, p. 470, p. 521. (e) Same, vol. Ixix. p. 6. 1779. EXCISION OF THE JOINTS. 727 (1) White (a) performed this operation in the year 1769. It had been previously done by Vigaroux and David (6), although their operations were only published at a later period. (2) Wachter (c), Vermandois (d) Kohler (e), Chussier (/), and more re- cently Heine have performed experiments on animals which have supported the proposition. 2824. In regard to the fitness of this operation, and in comparing it with amputation, the following have been specially stated as objections; the difficulty of its performance, especially on large ginglymoid joints, the danger of violent inflammation and wasting suppuration, the tedious- ness of the cure, and, particularly, that after the removal of the joint-ends of the bones of the lower extremities in consequence of the shortening and stiffness of the limb which remains, it is only retained in a condition far worse than the use of an artificial limb after amputation, which is much less dangerous. According to the cases as yet published, many of these objections have lost their importance, and are contradicted by ex- perience. It must, however, be admitted that the removal of the ends of bones is more difficult than amputation or exarticulation, yet the danger during and after the operation is not greater than in amputation, and the symptoms are not usually severe ; the cure, indeed, is more tedious but accompanied with fewer inconveniences, (Syme, Jaeger,) and with the preservation of the limb the patient finds it generally in a very useful condition. As regards the removal of the joints of the upper ex- tremities, these circumstances are no doubt of the greatest importance, and to a certain extent influence its preference to amputation, as the pre- servation of the arm, even with confined motion, is not to be compared with its artificial supply after amputation, and experience of the conse- quences of the removal of the joints of the upper limbs points to the most favourable results. This operation on the lower limbs cannot, however, be considered so advantageous; it is here manifestly more dangerous, the after-treatment more tedious and difficult, and the result as to the capability of using the preserved limb, in many instances, in- complete ; so that only under peculiarly favourable circumstances should the removal of the joint-surfaces be here performed. These statements are founded on the cases hitherto published. Of Jaeger's col- lection of fifty-three cases of excision at the shoulder-joint but two had an unfavour- able result; of thirty-four at the elbow only four; arid in three at the wrist all were successful. In regard to excision at the wrist it is remarkable that Syme (g), otherwise so warm an advocate for the operation, gives a most unfavourable opinion, that it is very difficult to perform, that relapses easily recur, and that it leaves a stiff and unusable limb. He, however, admits that these objections are supported only by theory, and that experience might, perhaps, show them to be of less impor- tance. Of thirteen excisions of the knee-joint, upon careful observation six were perfectly successful, three imperfectly so, in reference to the capability of using the limb, and three were fatal; a proportion decidedly less favourable than in amputation, but not so bad that excision of the knee-joint should be unconditionally rejected. Upon this point Syme (h) observes, that excision must always be con- (<*) Philosophical Transactions, vol. lix. p. (d) Journal de Medecine, Chirurgie, et 39. 1769. Pharmacie, vol. lxvi. p. 200. (6) Pavid (fils), Dissert, sur l'lnutilite (e) Experimenta circa Regenerationem de l'amputation des Membres dans la plupart Ossium. Exp. 14,15,16, p. 84-98. Gotting., des Maladies de la contiguite des Os. Paris, 1786. an xi. (/) Above cited. (c) Above cited. (g) Above cited, p. 119. (h) Above cited, p. 131. 728 EXCISION OF THE JOINTS. sidered more dangerous than amputation when the patient is very weak or has been wasted by previous disease; but if he possesses moderate powers, it is not to be supposed either from general circumstances or from the results of experience that excision is attended with greater danger than the removal of the limb. It must, however, be mentioned that a larger number of cases would give us a more decided opportunity of comparing excision of the knee-joint with amputation. In five cases of excision at the ankle-joint the result was successful, and in twenty-four cases where it was performed for compound dislocation but one patient died. Syme (a), however, says, that although excision of the ankle joint has not the objections to it that that of the wrist has, it cannot be extolled as of any great use. It affords, indeed, a support for the body, and it may be questionable in how far the foot, after the excision, is better than an artificial apparatus. Moreau's experience also shows that anchylosis generally occurs after, the operation ; and although, as he observes, the other joints of the foot become more moveable, so as in some measure to make amends for this stiffness/, there can still be no doubt that the foot loses much of its elasticity (b). [Upon the excision of joints Crampton (c) observes:—" It is impossible not to be struck by the fact, that the constitutional disturbance succeeding to the excision of even so large an articulation as the knee-joint, bore no comparison in kind or in degree, with that which experience has proved to be the invariable attendant upon simple penetrating wounds of a joint, when union is not effected by the first inten- tion. This difference in the'symptoms may, I think, be referred to that well-known principle of the animal economy, which disposes the system generally to suffer in proportion as the injured part is possessed of a higher or lower degree of sensibility, and as the injury is more or less difficult of cure by the proper forces of the consti- tution. Now, although it be true that when in a healthy state the parts which enter into the composition of a joint'are possessed of but a low degree of sensibility, still it is well known that when suffering under disease there are no parts in which inflammation is attended with more exquisite pain, or in which the actions which tend to recovery are more slowly or imperfectly performed. It is not surprising, therefore, that a penetrating wound of a large articulation should be succeeded by a train of the most painful and dangerous symptoms. By the total excision of the joint, however, all those parts, which when diseased, influence the constitution so unfavourably are removed from the system, and the injury is resolved into a case of clean incised wound, with a divided but not fractured or diseased bone at the bottom of it." (pp. 207,208.)] 2825. All the cases in which excision of the ends of bones is to be preferred to amputation of the limb, may be thus considered :— * Caries and necrosis of the joint-ends, of tubular bones, which does not spread further. £ Crushing of one or several joint-ends, without further considerable splintering of the bone towards its body, without injury of the principal artery and nerves, and without great destruction of the soft parts. y When, under like circumstances, a musket-ball remains sticking in the spongy structure of a joint-end, and cannot be withdrawn. eighth, the |—{ cut; and ninth, the £""7^ or elliptical cut. For making these cuts, a pretty strong knife should be used ; the flaps therewith made separated from the bone, turned back, and held with a blunt hook, or by the fingers of an assistant, the ligaments cut into and divided, the head of the bone dislocated, and separated from the soft parts to the extent of the disease, and the periosteum there cut through. If possible, the joint should be at once opened in making the cut through the skin, and the ligaments lifted up with the flaps, as thereby the whole operation is shortened, the pain diminished, and the cut has more posi- tive direction. After the spouting vessels have been tied, a wooden or horn spatula, a plate of lead, or a strip of leather or of linen, should be passed between the soft parts and the bone, to separate them from each other, and then the edges of the wound are brought together with the assistant's fingers or with a blunt hook. 2828. Close upon the spot where the periosteum has been divided, the bone must be cut through with a moderate-sized saw, or if it be not very strong and hard, with the bone-nippers, and every splinter removed with a little saw, the nippers, or the file. The still spouting arteries must be tied, the thickened ligaments, and capsule of the joint, together with all superfluous skin, removed, the whole wound cleared of blood, and care- fully examined both with the finger and the eye to ascertain whether any- thing hurtful remains, that it may be removed. In determining the boundary of the diseased bone, not merely must the extent of the caries be considered, but also the extent to which it has been separated from the periosteum, for if that part be left, caries or necrosis is quickly set up on it. In such [a) Rust's Handbuch der Chirurgie, above cited, p. 582, Vol. iii.—62 730 OF EXCISION OF JOINTS. cases the cut must, therefore, be extended into the firmly-attached periosteum, and the bone must be sawn through there. If the caries run into the spongy end of the bone, a plate of bone of corresponding depth to the caries must be sawn off, in which case the application of the white hot cautery-iron, according to Moreau, generally increases the necrosis, and delays the cure (Jaeger.) If the bone be diseased more extensively than was supposed, amputation was generally required; however, in regard to this, every thing depends on whether a large piece of bone can be removed from each or from only one of the bones of a joint, as well also as on the condition of the joint; thus, for instance, at the shoulder, five or five and a half inches of the upper-arm-bone have been successfully removed. Of the numerous instruments which have been recommended for removing the ends of bones '(a), the most convenient and applicable for all cases are, the common large and smalt bow saw, the knife saw, Hey's saw of different sizes, Jeffray's, (Aitkex's,) B. Heine's chain saw, the bone-shears and nippers, variously-formed chisels, which although they jar both the bone and the neighbouring-joint, and in- crease the pain, are often indispensable. Sometimes it may be convenient to divide the bone partially with the saw, and then to use the nippers, with which the piece of bone can be easily removed. The trickling of the blood from the wound is commonly stopped by exposure to the air, or with cold Water; but if it come from a spongy and thickened tissue, this must be removed, and cold water or some other styptic must be applied. Bleeding from a bone, when it cannot be checked by pressure with a sponge dipped in cold water, requires pressure with German tinder, with lint dipped in spirit of wine, or with little balls of wax. Severe venous bleeding, if it do not cease after the removal of the tourniquet, and after repeated inspiration and expiration, requires the application of cold water, or some other styptic. If the principal trunk of the artery or vein be wounded, which can only be done by awkwardness or carelessness, it must be tied; but, in-general, amputation will be necessary. 2829. In applying the dressing, which according to Jaeger, is best done after the patient has got to bed, the limb must be laid on a pillow covered with oiled cloth, the ends of the bones put into proper, place, either touching or not, and the edges of the wound brought together with the interrupted suture. Only when the teguments are so very thin that they would be cut through by the pressure of the suture-threads, should compresses of lint be applied to support them (Syme.) The most de- pending part of the wound must be left open for the escape of the dis- charge. The wound must be covered with lint, the part carefully raised, and another oiled cloth with the Scultetus's bandage, compresses, and lint, laid upon the pillow, the limb placed on it in the position most proper for its future use, the several parts of the dressing applied, and, if necessary, secured with a suitable splint. Jaeger's practice, however, of surrounding the limb with compresses dipped in cold water and simply laid on1 a pillow till suppuration come on, seems to be best, as at this time Scultetus's bandage can never be applied so firmly as to give hope of keeping the bones together. Syme's assertion that, after putting the limb in proper position, to swathe it in a long roller affords the necessary support better than splints, or stiff pieces of tin or pasteboard, is manifestly incorrect. 2830. The after-treatment must be conducted according to the usual rules for wounds and amputations. The traumatic reaction is, according to the concurrent testimony of most observers, not great, and requires, at first, besides keeping the patient quiet, strict diet, mucilaginous drinks, and the use of cold applications. If there be little reaction and a cold cedematous state of the parts, warm aromatic fomentations should be em- ployed, and a more nourishing and exciting diet. When suppuration (a) Jaeger, above cited, p. 584. OF EXCISION AT THE SHOULDER-JOINT. 731 begins the cold applications must be given up, and the wound dressed with lint and sticking plaster and bound up with Scultetus's bandage, to check any unnecessary movement of the arm. On the fifth day, those stitches which are most stretched must be removed, and the others ac- cording to circumstances from the sixth to the ninth day.' When the fever subsides, more nourishment must be allowed, and the patient, usu- ally about the eighth day, will have returned to his ordinary diet and drink. The scarring, in general goes on quickly, and only now and then does the wound remain open longer {a). 2831. Among the untoward circumstances which may occur during the after-treatment, the following may be specially noticed, after-bleeding, abscesses, fistulous passages, and ulceration of the scar. If after-bleeding come on soon after the operation, the dressing must be removed and the bleeding vessels tied. If there be trickling from the whole wound, cold applications and styptics must be used. During sup- puration, if large bleeding come on, amputation will be necessary, as tying the great arterial trunk does away with the least hope of a favour- able result. Abscesses which are formed by extension of the inflammation, or by the burrowing df the discharge into the neighbourhood of the operation, require poultices and to be opened with the knife. Fistulous passages depend either on the continued secretion of synovia from a still remaining portion of the joint-Surface, or on sluggish granula- tions of the thickened callous tissue, or on some carious part remaining,- or on superficial necrosis of the edges of the bone, and require the con- tinued use of aromatic applications until, in the latter case, small splinters of bone be thrown off. JVecrosis after decapitation, according to Jaeger, rarely or never af- fects the medullary cavity. Any remaining carious part, if it do not heal after the above-mentioned treatment, requires a second excision, or if it spread, amputation. 2832. The mode of dressing the sawn-off ends of the bone requires particular attention in the after-treatment.. In the upper extremity the formation of callus should never be the object. On the contrary, how- ever, in the lower limbs, a!nd specially at the knee-joint, every thing must be directed towards its production, and attention paid to the motions it will have to perform, or that state of rest in which it is to remain. If no callus form, a tough fibrous tissue which grows and connects the ends of the bones affords the limb sufficient firmness. If no firm union take place, if the limb be thereby rendered useless and not fixable by a firm enclosing bandage, it must be amputated. I.—OF EXCISION AT THE SHOULDER-JOINT. (Excisio Scapulo-humeralis, Lat; Ausrottung im Schultergelenke, Germ ; Resection Scapulo-humirale, Fr.) 2833. The most important proceeding in excision of the head of the upper-arm-bone is to form an upper flap, as in La Faye's exarticulation, (a) Jabger, above cited, p. 394. 732 EXCISION AT THE SHOULDER-JOINT. {par. 2810,) to divide the connexions of the joint, to lift out the head of the arm-bone, and whilst a wooden spatula is passed beneath it for the protection of the soft parts, to saw if off. When the bleeding vessels have been tied, the sawn surface of the bone must be brought near the lower edge of the glenoid cavity, the flap laid down and fixed with sutures and strips of plaster, covered with lint and compresses, and the arm kept in proper position, by means of such bandages as Desault has described for fractured collar-bone. The after-treatment must be con- ducted in the same way as that of amputation, and bagging of pus must be especially prevented. C. White, Orred and others, operated with a longitudinal cut from the socket of the shoulder-joint down to the insertion of the m. deltoides, and then having divided the tendon of the long head of the m. biceps, lifted out the head of the bone and sawed it off. This method seems most preferable in all cases where only fragments of the crushed head are to be removed. In chronic affections of the joint it must be presumed that dislocation of the head of the bone is easy under particular circum- stances, that the ligaments are not very thick, and the like. Bent formed a flap from the outside of the joint by one vertical and two horizon- tal cuts, running outwards from it. Sabatier made a V flap from the deltoid muscle. Moreau thrusts in a scalpel, at the most prominent part of the coracoid process, to the bone, aud cuts the skin and deltoid muscle directly downwards to the length of three inches; next makes another cut parallel to it, beginning from the back part of the lower edge of the acromion, then connects both with a transverse cut across the acromion, separates the flap and turns it down. The tendons and capsular liga- ment are now divided, the head of the hone lifted out, a long pad introduced between it and the soft parts, and then the head is sawn off. If the caries affect the glenoid cavity and the acromion, Moreau lengthens the front cut over the outer end of the collar-bone and the hind one to the spine of the blade-bone; separates this new flap, removes the carious part with the bone-shears or the chisel, and then fixes the upper to the under flap. Especial care must be taken that as much as possible of the capsular ligament should be cut off to prevent inflammation and profuse suppu- ration. Syme makes a vertical cut from the acromion through the middle of the deltoid muscle, nearly to its attachment, then a shorter one from the lower edge of the for- mer upwards and backwards, so that the outer part of the muscle is cut through. After this flap has been dissected up, the joint comes in sight, and when the capsular ligament, if existing, has been divided, the surgeon passes his finger around the head of the bone, so that he may feel the attachments of the m. supra-spinatus, infra- spinatus, and subscapularis, which he easily cuts through by turning the knife first towards one and then to the other side. The movements of the arm should be pre- vented, to guard against irritation and displacement, and the latter by putting a pad in the armpit. 2834. After this operation the motion of the arm may remain under various circumstances:—-first, the upper end of the remaining, part of the upper-arm-bone may be drawn back to the glenoid cavity ; second, it may be drawn from the outer edge of the blade-bone to the trunk; or, third, separated from it, may remain isolated in the soft parts. In the first case, a new perfectly free joint takes the place of the old one; in the second, an imperfect joint is formed without much motion ; and in the third, the lever of the arm remains without any fulcrum, which, however, does not offer any obstacle to the direction and freedom of the movements pre- served (a). (a) Moreau, above cited, p. 31.—Textor, Ueber das Absagen des oberen Endes des Humerus; in Neue Chiron, vol. i. part. iii. [ 733 J II.—OF EXCISION OF THE ELBOW-JOINT. (Excisio Humero-cubitalis, Lat; Ausrottung im Ellenbogengelenke, Germ; Resection Humero-cubUali, Fr.) 2835. Moreau's (a) method of sawing off the elbow-joint is as follows; The patient lies on a table covered- with a mattress, upon his belly, so that the ailing arm may be put at a right angle with the trunk, at the edge of the table, in the strongest light, and/the hind part of the half-bent elbow may be opposite to the operator. One assistant holds the upper and another the lower end of the limb, and the brachial artery is com- pressed with a tourniquet in the upper third: of its course; A cut of three inches length is now made, with a single-edged scalpel, on each side of the lower end of the upper-arm, to the pit of the condyle, and both are connected by cutting through the skin and tendon of the m. triceps; the flap is now dissected upwards from the bone and held by an assistant. , The fibres of the m. brachialis internus are next separated on the inner and outer side, from the: bone, and an ivory spatula-shaped retractor passed between it and the soft parts. The elbow is held fast with the left hand, and that part of the upper'arn>bone to be removed is sawn off with a large saw by the right hand. The fore-arm is then dropped, the upper end of the sawn-off piece of bone lifted up, the knife carried in front of it, its connexions separated, and as it is set free, it must be decided how it can be removed without violence. If both ulna and radius, at their connexion, with the upper-arm-bone j. be deeply affected with caries, the fore-arm must be lifted up, a cut, an inch and a half long, made on the outer edge qf the upper end of the radius, and a like one on the hind-edge of the ulfia. The flap between the two cuts is now separated downwards, the head of the radius freed from its connexions, a fold of linen, in place of a retractor, passed between it and the soft parts, and the diseased part cut off with; a small saw, in such a way as to preserve the insertion* of the m. biceps. In like manner the upper end of the ulna is laid bare, protruded by raising the fore-arm, the carious part sawn off, endeavouring* to keep the whole or part of the insertion of the m. brachialis internus. After tying the vessels and cleansing the wound, the two flaps are brought into place and fixed with five sutures, the wound covered with lint and compresses, and a Scultetus's bandage. The arm is to be laid half bent upon a pillow. Dupuytren (b) forms, like Moreau, two flaps on the hind partof the joints then draws out the olechranon so that the ends of the bone may be better protruded. Syme also first removes the olechranon, cuts through the lateral ligaments for the purpose of freeing the lower end of the- upper-arm-bone and then cuts it off. He then takes hold of the head of the radius with the cutting forceps, and removes the remaining part of the sigmoid' cavity. The reason he gives for not at once remov- ing the whole piece of the ulna is, that if cut through below the attachment of the m. brachialis internus, its removal is very difficult. According to Moreau, the ulnar nerve must be cut through, by which sensation and motion is partially destroyed. Dupuytren recommends saving this nerve, by dividing the fibrous sheath in which it is contained, and lifting the nerve with a spatula over the inner condyle, where it is to be held whilst the bone is sawn off. Crampton and Jaeger are of the same opinion. Syme also preserves the nerve, which lies close to the inner edge of the olechranon, and will certainly be cut through (a) Above cited, p. 42. 62* (b) Sabatier, p. 451. 734 OF EXCISION OF THE WRIST-JOINT. if the transverse cutbe made beyond the olechranon towards the inner condyle. The ole- chranon must therefore be felt for and the knife thrust into the joint, with its back towards the inside, close along the upper surface of the olechranon, but a little near- er the radial side, and then cut transversely with a sawing movement, for the pur- pose of dividing completely the tough tendinous parts till the radial tuberosity is exposed. Jaeger, in the absence of fistulous passages, always lays bare the ulnar nerve: he ascertains its position by feeling on the inner condyle, and then carefully makes a cut two, or two and a half inches long, upon it, of which the middle is upon the condyle; then opens the sheath of the nerve, takes hold of and lifts it up with a blunt book, separates it from the soft parts, lifts it over the inner condyle, and there has it held fast, with a blunt hook. With the left hand he now grasps the fore-arm, and, by bending it towards the upper, renders the m. triceps tense, cuts through it with a strong scafpel,a quarter of an inch above the olechranon from the inner to the outer condyle, and opens the joint, the bending of the arm being still increased, the lateral ligaments and skin upon the condyles are still further cut through. The further progress of the operation depends on the extent of the caries; if but one condyle be affected on its joint surface or on its outer side, the longitudinal cut must be con- tinued upwards to the extent of the caries; in paries of the whole cubital process, a longitudinal cut of an inch and a half or two inches length, must be carried from each side to the pit of the condyles, the flap dissected back to the part where' the bone is to be sawn through, and the operation finished according to Moreau's method. If the cubital process be healthy, the lower longitudinal cut of from one and a half to two inches, must be made from, the inside of the olechranon and the outer part of the head of the radius. If the upper cut be already made, it must be continued downwards to the requisite extent, and the lower flap dissected from the ulna. If the radius be carious, a simple cut must be carried over its condyle to the extent of the caries.. After excision of the elbow-joint the radius and ulna always remain separate, al- though they are near together and held by the soft parts. The hand retains its power and mobility, and the fore-arm its most important motions. Every thing, however, depends on the circumstance, whether the insertion of the m. biceps to the radius, and of the m. brachialis internus to the ulna can be preserved. Jaeger's case, how- ever, shows that motion of the fore-arm is possible, when even the insertion of the m. biceps has been destroyed.. [Crampton first performed this operation in Dublin, in February, 1823 ; but no account of it was published till 1827. Syme gave (a) an account in 1829 of three cases in which he had performed it.—j. f. s.] III.—EXCISION. OF THE WRIST-JOINT. ([Excisio RadiO'Carpalis, Lat; Ausrottung im Handgelenke, Germ,; Resection du Poignet, Fr.) , 2836. For the excision of the lower part of the radius and ulna, first performed by Orred and Moreau, Roux {b) gives the following direc- tions. Two longitudinal cuts are made, one along the outer edge of the radius and the other along the inneE edge of the ulna, as near as. possible to its inner, edge, to the wrist-joint, without injuring the vessels or nerves; a transverse cut is then made across the palmar and dorsal surfaces of the arm, avoiding the tendons. The lower end of the radius and ulna are then laid bai;e, sawn through, and the diseased carpal bones removed. According to Jaeger (c), in excision of the ulfia at the wrist-joint, the arm must he placed on its radial side, so that its ulnar side be before the operator, the hand bent in the opposite direction, the skin made tense (a,) Edinburgh Medical and. Surgical Jour- (b) Above cited, p. 54, nal, vol. xxxi. p. 256. 1,829. (c) Above cited, p. 67.8.. OF EXCISION OF THE HIP-JOINT. 735 with the left thumb and fore-finger, and a cut begun upon the styloid process, and carried up two inches on the outer side of the ulna. From the lower end of this another cut is made, from three-quarters to an inch long, through the skin on the dorsal surface of the joint, the flap dissected off and the tendon of the m. extensor carpi ulnaris lifted up with a blunt hook. The ulna is now laid bare on the upper and under surface, the joint cut into above and on the side, whilst the hand is bent rather to the other side. The skin and tendons are then held back with a blunt hook, and either a small Hey's saw or a phalangeal saw applied at the upper sound part of the bone, which is then sawn through. The piece of bone is now taken hold of with the forceps, drawn out and rolled downwards, and its inner connexion with the radius divided. The end of the ulna is then seized with, a sharp double hook, drawn forwards, and its con- nexion with the radius at the joint divided. In excision of the radius, the arm is placed on its ulnar side, a cut two inches long is made upon the inside of the lower part of the radius from above downwards to its styloid process, and from the lower angle of this wound a transverse cut, an inch and a half long, upon the dorsal side of the wrist. After the flap of skin has been dissected up, the sheath of the tendons is cut into, the tendons separated on both sides from the radius, and held by a blunt hook. The ligaments are made tense by bending the hand in the opposite direction, cut through from above and on the side, the radius dislocated, and as much of it sawn off with the phalangea saw as had been sawn off the ulna. After cleansing the wound the fore-arm and hand are laid upon a pil- low, the ends of the bones brought together, the longitudinal and trans- verse cuts united with, sutures and the angles of both wounds left open. The joint is surrounded with, oiled cloth and compresses dipped in cold water applied ; when suppuration has set in Scultetus's bandage is to be put on. Dubled makes a longitudinal cui on the ulnar side of the wrist, draws the edges of the wound asunder, divides the lateral ligaments, abducts the hand, isolates the end of the ulna and protrudes it as far as possible outwards, separates it from the radius, passes a wooden spatula between them, and- saws through the bone above the diseased part. The method laid down by Velpeau does not answer the purpose;: it consists in connecting the longitudinal cuts on the side by a transverse cut oij the back of the hand, and the flap being dissected back; in the soft parts being separated from- the front of the bones, and1 in, a plate of wood or lead being pushed through, upon which the radius and ulna are sawn through, and the connexions of the joint divided one after the other>. [Butt (a) of Portsmouth, Virginia, U. S., removed a large portion of necrosed ulna, sawing it through about four inches below the olechranon, and. exartic'ulating it at the wrist. In three months the man was able to return to hi? trade as a car- penter, with flexion, extension, and rotation of the joint as uninterrupted; as ever.] IV.—OF EXCISION; OF THE HIP-JOINT. (Excisio Coxae, tat-; Ausrottung in Huftgelenke, Germ.; Resection Cexofemorale-,]?!.) 2837. Excision of the head of the thigh-bone, which in the seven cases (a) Philadelphia Journal, vol.. Lp. 117. 1825. 736 OF EXCISION OF THE HIP-JOINT. hitherto published has had but one successful result, has been variously given in reference to the direction and nature of the cut. First. By a simple longitudinal cut which, beginning an inch or two above the great trochanter descends three inches below it on the outer side of the thigh. After the division of all the tendons, the opening the capsule and division of the round ligament, the head of the thigh-bone is dislocated by turning the knee inwards, and then sawn off' (White, Vermandois, Seutin, Oppenheim, and others). Roux holds a single vertical cut insufficient to lay bare properly the head of the thigh-bone, and suitable only in cases of destroyed ligaments and gun-shot wounds. Oppenheim, (a) considers a simple cut as the best method, inasmuch as it is the most simple, is least injurious and heals most readily. Second. By the formation of a flap,, either as a* A |J shaped flap on the outer side of the joint, according to the method of Percy and Roux; or /3. A triangular flap, according to Jaeger's plan, by a longitudinal cut beginning from two to two and a half inches above the great trochanter, and descending three inches below it, so as to make in the whole a cut, from four and a half, to five and a half inches long, from the upper end of which a second cut of four inches is carried backwards and downwards. The triangular flap thus formed is dissected up, the insertion of the mus- cles at the upper and fore part of the trochanter Cut through, the capsular ligament, and every spouting vessel tied, the head of the thigh-bone dis- located by turning the knee inwards, the round ligament cut through, a spatula passed under the neck of the thigh-bone, and that or the great trochanter sawn through with a small bow- or knife-saw. If the upper edge of the hip-socket be carious, it may be removed with Hey's saw, and the socket itself touched with the actual cautery, y. A semilunar flap, according to Velpeau, in which the cut is carried from the front upper spine of the ilium to the ischial tuberosity, and a semilunar flap with its convexity downwards, is dissected up, and the back of the joint opened. Hewson's method of making a semilunar flap above the tro- chanter, and turning it downwards, is inefficient. And like it is Jaeger's semicircular cut carried round the great trochanter with its convexity upwards. Third. By Textor's oval cut; he makes a cut beginning two inches above the great trochanter, carries it obliquely backwards and outwards, and ends it about an inch before the little trochanter. To this first cut follows a second, which, beginning on the front of the thigh opposite the point where the former ended, is carried obliquely outwards and upwards, and meets with it at a rather acute angle above the great trochanter. This second cut at first divides only the skin, but afterwards is continued down to the neck of the thigh-bone. The soft parts are then separated from the great trochanter, the capsular ligament cut into with a strong scalpel from within outwards, following always the edge of the hip-socket, over half its extent, down to the head of the thigh-bone, the knee being then bent inwards, the round ligament is divided with the scalpel, the head of the bone dislocated, fixed with the hand, and a knife carried round the part where the bone is to be divided, so that the track of the saw may be made easy and then the bone cut through with the osteotome, or with a small bow- or knife-saw. (o) Hamburger Zeitschrift, vol. i. part ii. OF EXCISION OF THE HIP-JOINT. 737 When the operation has been finished, the vessels tied, and the wound cleansed, some sutures are put in at the upper part, and supported with straps of plaster, but the lower end is left open with a strip of linen in it, to favour the escape of the discharge. The wound is covered with lint and compresses, which are kept together with a cloth passed around. The feet may be tied together, or, if circumstances permit, Hagedorn's appa- ratus may be put on. Of the seven eases, published, of excision of the neck of the thigh-bone, but one has terminated successfully. It is incorrect to include with these, those cases in which the head of the thigh-bone had been completely destroyed by caries, or had been removed necrosed, (Schmalz,) as well as the mere sawing through the neck of the bone in anchylosis, (Barton, Rogers.) A case of Kluge's (a) and one of Ohle's (6) are doubtful. Anthony White (c), cut off the head of the thigh-bone in a boy of fourteen years, on account of very severe hip disease; four inches of the bone were removed, it formed a very useful artificial joint; the patient lived five years, and could use the bone perfectly well; it did not even appear much shortened. Carmichael (d) per- formed the operation on a young woman for medullary sarcoma of the thigh, but she died next day. Oppenheim (e) performed it on account of a crushing of the head and neck of the thigh-bone, and of the great trochanter, by a musket-ball; he sawed off the lower end of the fracture close to the little trochanter, enlarged the wound upwards, and after dividing the capsule and round ligament, he removed the three pieces of the head and also the bullet. The patient died eighteen days after. Hewson (f) performed this operation for caries; the bone was sawn off above the little trochanter. The patient died three months after, in consequence of the burrow- ing of a large quantity of pus, which passed by an opening in the hip-socket into the pelvis. Seutin (g), in a gun-shot wound which had split the neck of the thigh- bone to pieces, and injured the soft parts but little, made a cut from the crest of the hip-bone, to three inches above the great trochanter, adducted the limb, dipped into the bottom of the wound, and removed fifteen loose pieces of bone of various size and form ; the lower fragment of the bone was lifted out of the wound and sawn off beneath the lowest split portion. The getting out the head of the bone, which was broken immediately in the cavity of the socket, was difficult; including the neck and head, six inches of the bone were removed. The contentive apparatus, and a half- bent posture on a double inclined plane, were employed. The patient died on the ninth day, of gangrene. Textor (A) has operated three times. In the first case, on a child seven and a half years old, on account of fracture of the neck of the thigh-bone, and abscesses following; the head of the bone, and two inehes from the great trochanter, above the little trochanter, were removed. In the second case, in a young man of eighteen, for caries of the head of the bone, the patient died on the fourth day. In the third case, in a man of fifty-four years, on account of caries of the great trochanter, and of the neck of the thigh-bone, six inches were removed, and the patient died on the fifty-third day. The interesting results after removal of the head of the thigh-bone in brutes, in reference to the regeneration of bone, are given in Heine's {i) experiments. [Charles White would seem to have been the proposer of estision of the head of the thigh-bone, although he did not perform the operation, for he observes (j):— " I have likewise in a dead subject, made an incision on the external side of the hip-joint, and continued it down below the great trochanter, when cutting through the bursal ligament, and bringing the knee inwards, the upper head of the osfemoris (a)WAGNER, Article Decapitatio; in Buscb, (/) Oppenheim, above cited. von Graefe, Hufeland, and Rudolphi's En- (g) Gazette Medicale de Paris, vol. i. p. cyclopaedisches Wflrterbuch, vol. ix. p. 188. 135. 1833. (6) Schmidt's Jahrbuch, vol. ii. part. i. p. (A) Lepold, F., Ueber die Resection des 116. 1834. Huftgelenkes. Wurzburg, 1834.—Oppen- (c) London Medical Gazette, vol. ix. p. 852. heimer, S., Ueber die Resection des Hiift- 1832. gelenkes. Wurzburg, 1840. (d) Oppenheim's Zeitschrift, vol. i. (i) Oppenheimer, above cited, p. 51. (e) Above cited. (j) Cases above cited. 738 OF EXCISION OF THE HIP-JOINT. hath been forced out of its socket, and easily sawn off; and I have no doubt but that this operation might be performed upon a living subject with every prospect of success. The Royal Academy of Surgery at Paris proposed for a prize question, whether amputation of the thigh at its articulation with the os innominatum, was ever advisable; but, was I under a necessity of performing this operation, or that which I have been describing, I should not hesitate a moment which to prefer." (p. 66.) The first successful excision of the head of the thigh-bone was performed in West- minster Hospital by Anthony White, in April 1822, to which Chelius refers above, from the slight notice by Beale. It has since been fully published by S. Cooper (a), from notes furnished by White, who has also kindly given me the following more consise account.—jr. f. s. Case.—" John West, when nine years old, slipped down stairs and slightly hurt his left hip. After a few weeks, he was observed to limp in his gait, and complained of stiffness and pain in his groin ; and subsequently he lost the power of locomotion, had the usual symptoms of disease in the hip-joint, and the head of the thigh-bone became displaced and rested far back on the dorsumilii. He suffered very acutely, and underwent ihe usual treatment'of cupping, blistering, with every mode of local and constitutional treatment for many months, but without benefit, and after a time suppuration in the joint took place, which was .evacuated from the front and upper part of the thigh. Temporary relief was thus obtained, but during two years a succession of similar abscesses formed around, and small portions of bone were fre- quently protruded through the sinuses which remained, and more especially, from those formed over the pubes. At the end of the third year he was in the greatest possible state of emaciation, no longer suffering7 acute pain, but exhausted by the previous suffering and by an overwhelming discharge from numerous apertures. The integuments over the displaced bone had become at various parts absorbed, and the bone at these points was readily found to be in a state of superficial caries. The knee had been long imbedded and immovably fixed on the inner side of the opposite thigh, and the right side on which he could alone lie was cruelly galled with bed- ridden ulcerations. The formation of fresh abscesses had for some months ceased and further diseased processes were not apprehended. In the month of Aprilit was determined, on consultation with Travers, to remove the head of the bone ; the cir- cumstances of his health, with the exception of great emaciation, not forbid- ding it. Operation.—" An incision was first made through the integuments, beginning about an inch above the point where the head of the femur was deposited, and then carried down the centre of the bone to a point as far as was considered necessary for sawing through it. The integuments were then separated on each side, making their dissection as close to the bone as possible. The straight saw was then used and the femur divided without difficulty about two inches below the top of the great trochanter and including the little trochanter. So closely adherent was the upper por- tion of the bone to the ilium, that I was compelled to introduce a spatula between the sawn ends and used it as a lever, by which he was enabled to detach the subjacent parts, and to finish the operation. A very small quantity of blood was lost, and the boy suffered less than was anticipated. The bone had lost very little of its original form ; the round ligament and the cartilage were gone, and the head of the bone was slightly affected with superficial caries. Several patches were also seen on other parts where absorption of the surface had taken place. Neither the finger nor probe could detect anyTOorbid condition of the ilium, but the original site of the acetabu- lum was not to be- found. " The knee was now gently carried oHtwards, the removal of the fixed head of the femur now no longer acting as opposing that movement; and the divided end of the bone which had been exposed during the operation was thus brought deeply into the wound. After the dressing and application of bandages necessary to retain the parts in their new situation, and also to secure the limb in the straight line with the body, he was put to bed upon his back, and treated as for compound fracture. A slight attack of symptomatic fever ensued, which did not continue beyond a few days. " The wound quickly healed; the various sinuses soon ceased to discharge, and the health of the patient speedily improved. Within twelve months he enjoyed a most useful compensation for the loss of the original joint; had perfect flexion and exten- (a) Dictionary of Practical Surgery, p. 272. Edition of 1838. OF EXCISION OF THE KNEE-JOINT. 739 sion of the thigh, and every other motion except that of turning the knee outwards. The limb, of course, remained shorter, by as much as had been cut off from the top of the thigh-bone." He died five years after the operation, of phthisis, and an op- portunity was thus obtained of ascertaining the condition of the parts. Examination.—The thigh-bone had been sawn off a little below the less trochanter; the upper end of its shaft was largely covered with fibrous tissue and very loosely though firmly connected on the inner side with a mass of this structure which filled up the hind part of the hip-socket, so that the top of the shaft lay against but not at all supporting the upper lip of the socket, the front of which seemed filled with bone. It is probable that before the operation, as usual in cases of advanced disease of the hip-joint, the margin of the socket had become everted, and the whole socket shal- lowed. There was no appearance of synovial membrane, capsular ligament nor other part of a true joint. And the condition may be described as that of a soft anchylosis with the connecting medium so long as to admit of very free movement. The pre- paration is now in the Museum of the Royal College of Surgeons of England; and from careful examination of it, the account I have just given is drawn up.—j. f. s. The second successful case is Fergusson's (a,) who operated in March 1845, on a boy of fourteen years, who had been firstattacked with hip disease thirteen months previous. "The head of the bone could be felt through the soft parts, lying on the dorsum ilii, and its identity could be more accurately ascertained by passing the finger into a large sinus, which opened on the surface, over and behind the trochanter major. The articular extremity was.so isolated that the finger could be passed round it in all directions. * * * A longitudinal opening about six inches long, was made in the line of the femur, extending from over the head of the bone to a little be- low the trochanter major, and the tissues were separated from the shaft of the bone, so as to permit a curved needle to be used for the introduction of a chain-saw." This, however, broke, and " I was compelled to adopt another mode of procedure. With a sharp-pointed bistoury, I separated all the soft parts from the neck of the bone and the trochanters, and then, by causing the knee to be moved across the op- posite thigh, and using the femur as a lever, the head and portion of the bone thus isolated, was so thrust out of the wound, that I could with facility apply the or- dinary saw for.the requisite section. Not being satisfied with the condition of the interior of the bone at the surface exposed by the saw, I enlarged the opening, and removed about three quarters of an inch more, then closed the wound with a few points of interrupted suture, and covered it loosely with a pledget of lint. No ves- sel of sufficient magnitude to require a ligature was divided. The cotyloid cavity was filled by a fibro-gelatinous mass, similar to the lining of the sinus. When the patient was put to bed, a long splint was applied, with a view to keeping up gentle extension. * * * There was scarcely any shock succeeding to the operation, and the chief complaint was pain in the knee, which for some days after, was more severe than at any previous period. * * * The length of the bone removed was four inches and a quarter, measured through the curve of the neck and shaft, and the limb is now (after his recovery) two inches and a half shorter than its fellow. The cartilage was almost entirely removed from the head of the bone, and the surface was in a state of ulceration. The trochanter and rest of the shaft seemed in a healthy condition." (p. 572-76.) The operation was performed on the 1st of March, and on the 8th of May he was able to get up and move about on crutches. Some months after he was in good health, walked about on crutches, and had "free movement both at the knee and hip, and already at the latter part, has considerable power in elevating the thigh by the action of the psoas and iliacus internus muscles." (p. 579.) V.—OF EXCISION OF THE KNEE-JOINT. Excisin Genu, Lat.; Ausrottung im Kniegelenke, Germ ; Resection du Genou, Fr.) 2838. In excision of the knee-joint, according to Moreau's method, after placing the patient on his back, and compressing the femoral artery (a) Excision of the upper end of the Femur, in an example of Morbus Coxarius; in Med. Chir. Trans., vol. xxviii. 1845. 740 OF EXCISION OF THE KNEE-JOINT. with a tourniquet, two longitudinal cuts are to be made, one on each side of the knee, beginning from two inches above the condyles of the thigh- bone, and running down till they reach the shin-bone, where they are connected by a transverse cut below the knee-cap. This flap together with the knee-cap, is turned up, and the latter, if diseased, removed. The knee is then bent, so that the exposed condyles protrude on the sides, the soft parts very carefully separated from the hind part of the bone, pressed backwards with the left forefinger, and the bone sawn off. If the joint-ends of the shin- and splint-bones must also be removed, a longitudinal cut is made upon the front edge of the shin-bone, and the already-made outer cut lengthened to the head of the splint-bone; the two flaps thus formed are now turned down, the head of the splint-bone removed with a small saw, and afterwards the head of the shin-bone cleared and sawn off. After the bleeding is stanched, and the wound cleansed the soft parts are brought together and covered, with lint, com- presses, and Scultetus's bandage. The whole limb is placed on a long chaff pillow, and kept in this posture with two well-padded splints, so as to prevent any movement of the limb, but without pressing on it. Park made a longitudinal cut, beginning two inches above the knee-cap and end- ing two inches below it; then a transverse cut above it down to the thigh-bone, nearly in a half circle around the joint. He then removed the knee-cap, divided all the ligaments, and carried a narrow knife close above the condyles behind the thigh- bone, thrust in a spatula, sawed off the bone, and then protruded the head of the shin-bone forwards. Mulder (a) proceeded in like manner; only, after having cut through the thigh- bone, he bent the leg, by which the condyles were protruded, and then he sawed off the upper part of the shin- and splint-bones, having passed a spatula behind them. Sanson and Begin (b) recommend, after half bending the leg, to make a transverse cut from one lateral ligament to the other, and to divide them and the ligament of the knee-cap at a stroke. The joint surfaces of the thigh- and shin-bone are then easily laid bare; and by continuing the cut, according to circumstances, along these bones, the joint-surface of one or other bone may be protruded and thus easily sawn off. Jaeger proceeds in like manner, making upon a transverse cut nine inches long, which divides the ligament of the knee-cap and the lateral ligaments, two side cuts an inch long, of which each is distant about an inch from either end of the transverse cut -£—!-• According to Syme (c), two semicircular cuts should be made across the fore part of the joint, extending from one lateral ligament to the other, meeting at their ex- tremities, and including the knee-cap between them. Very free room will thus be afforded, which may be easily enlarged, if required, by cutting longitudinally at the point of union of the transverse incisions. The transverse cut, according to Jaeger's method has the advantage of at once affording a close insight into the seat and extent of the disease, and assists in the necessary variations of the operation. This proceeding is safer than Moreau's as the separation of the soft parts from the back of the thigh may be effected without the slightest danger, and the longitudinal cut may be rendered either unnecessary, or at least of but half the length formerly employed. According to Moreau, the cure does not take place by the union of the ends of the bones with callus, as Park, and Moreau, the father supposed; however, in Mulder's case even in twelve days after the operation, good callus had been formed ; and on cutting into it three months after, it was found well formed ; only a partial destruction seemed to have taken place in it by the suppuration. Jaeger is also of opinion that true bony union by callus follows very rarely, and that even in most of the successful cases, only a tough fibrous tissue, like the inter- (a) Wachter, above cited. (b) Sabatier, above cited, p. 457. (c) Above cited, p. 133. OF EXCISION OF THE KNEE-JOINT. 741 vertebral substance, or the ligamentous bands in many fractures of the neck of the thigh-bone, is formed, but which does not in the least oppose the movements of the joint, as there is a restricted artificial joint and a sort of motion. He correctly seeks for the causes of the non-union, in the very extensive removal of the ends of the bones, in the undoubted destruction of union by improper dressing, and the early movement of the joint. The whole of the condyles, therefore, should not be removed, so that the thigh-bone may rest with a broad surface on the shin-bone; such an ap- paratus should be applied that the limb should very rarely be lifted up to be used, and the knee should be free. For the first four weeks the patient should observe the strictest quiet, the splints should only be removed after the complete closure of the fistulous passages; and the first attempt at rotating the thigh should not be made before the tenth or twelfth week, and raising the leg only after sixteen weeks. Syme (a) believes that it is often very difficult after the operation to bring the limb exactly straight, on account of the contracted state of the flexor muscles, which prevent it being straightened, notwithstanding the relaxation, which arises from the shortening of the limb ; that it is best to place the limb on a double-inclined plane, and in as good a position as is possible, with suitably^strong pasteboard splints. In some days the tension ceases, and the bone must again be put perfectly straight. During the cure no absolute rest of the limb is observed, for the purpose of prevent- ing actual anchylosis or bony union, as the very long bone that would be thus formed, besides being very inconvenient, as the joint is stiff, would be also more exposed to the danger of being fractured, as it offers a long lever to any violence which may act upon the extremity. Great mobility WOuld render the limb useless. The prin- cipal difficulty in the cure consists in.preventing the tendency of the limb to bend outwards; as well, also, as in preventing too free motion. [I cannot refrain from noticing here a case of compound dislocation of the thigh- bone behind the leg which occurred to Anthony White some years since in West* minster Hospital, and from the following slight sketch of which* from memory, I am much indebted to him, as it is one of the most remarkable amongst, the many instances of constitutional power, in young persons, with Which I am acquainted. Case.—Matthew Burgess, aged seven and a half years, whilst running behind a cabriolet on August 2d, 1839, had his left leg caught in the wheel, which twisted and dislocated the condyles of the thigh-bone through a large transverse wound above the bend of the knee-joint, and extending a little in front of either hamstring. The twist was so violent, that the condyles were alsO forced through the leg of his duck trousers, where they lay, on his admission into the hospital in the morning. The trousers having been cut off and the parts examined, neither popliteal nerve, vein, nor artery were found in the pit between the condyles, and it was not certain that they had not been torn through. Attempts were made to replace the bone, but without success. Looking at the child's age, White was very averse to amputate the limb, and on consideration was determined to make an effort to save it. The boy was, therefore, left some hours that he !might recover the immediate shock of the accident, and towards evening having cheered up, White passed a broad plaster spatula between the front of the condyles and the skin of the calf of the leg upon which they lay, and without difficulty sawed them off. The saWn shaft immediately dropped into its place, and on passing the finger into the wound, Which could not previously be done, it was with much pleasure that the popliteal artery was found pulsating. The limb was then placed on the side with the knee a little bent, the wound dressed, and some splints applied to keep it steady. Directions having been given to cut a hole through the bed, so that his motions might be passed without alteration of his position, this was made so large that in the course of the night he slipped right through, and was found on the floor. He was immediately replaced and the appa- ratus re-adjusted. I am not informed how he went on, but at the end of a twelve- month, short of four days, he was considered well enough to leave the house, the wound being healed; but he could not bear upon his leg. Some months after a large abscess formed in front above the head of the shin-bone, and after the lapse of twenty months from the time of the accident, a large piece of bone about an inch thick exfoliated and came away. From this time his amendment was permanent, and about five or six months after he became able to bear on his leg, and at last to Vol. iii.—63 («) Above cited, p. 134. 742 OF EXCISION OF THE ANKLE-JOINT. walk, having a wooden pin, about four inches long, fixed on the sole of his shoe, which was firmly fastened to the back of his leg by a light iron shield fitted to it. January 5, 1847.—I saw the boy, now fourteen years of age, a stout lad. The thigh- and shin-bone are firmly anchylosed by bone, in a slightly bent posture. The scar is very distinct, and to the extent already described. The leg and foot are inclined a little outwards, so that the inner joint-surface of the head of the shin-bone juts forwards before the shaft of the thigh-bone, and is rounded. The connexion of the two bones seems to be complete right across. The knee-cap is distinct, rather small, quite free from anchylosis, and capable of being moved a very little from side to side, but quite sufficiently to show that its natural condition is unchanged. Above the knee-cap is the scar by which the exfoliated bone came away. The calf- muscles are larger than usual, I think, for a boy of his age, which is rather remark- able, as the m. gastrocnemius externus must have been completely deprived of its principal upper attachments.—j. f. s.] VI.—OF EXCISION OF THE ANKLE-JOINT. (Excisio Tali, Lat.; Ausrottung im Kniegelenke, Germ.; Resection du Pied, Fr.) 2839. Excision of the lower end of the shin- and splint-bones was first performed by Moreau (a) in the following manner:—The patient being laid on his sound side, on a table covered with a mattress, the knee bent and the leg resting on the whole length of its inner surface, one assistant grasps it above, and another at the foot. THe scalpel is thrust in perpen- dicularly upon the hind edge of the lower end of the splint-bone, the skin and cellular tissue cut through from above downwards, and the wound about three inches long, ends in a transverse cut, extending from beneath the outer ankle to the m. peroneus tertius. This flap is now separated from the surface of the splint-bone, turned up, and held 'upon the front of the leg. The m. peroneus longus and brevis are now separated from the part of the bone to be removed, which being cut off at the proper length with a sharp chisel, can be easily taken away. Through the same wound the lower end of the shin-bone is to be separated from all the soft parts attached to its outside. The patient is now to be turned round, the leg laid on its outer side, and a fresh flap made by one cut, three inches long, on the back and inner edge of the shin-bone, and another from ihe lower end of the former, running below the inner ankle to the m. tibialis anticus, and the flap then turned up. The fleshy parts attach- ed to the back of the shin-bone are then separated to the height deter- mined by the caries, so that the finger can be passed between them. The leg is then turned on its front, and carried so far from the other leg, that the operator can kneel down between its inner side and the edge of the table. A small narrow saw, with a blade six inches long, is now passed from within outwards, through the opening between the muscles and the bone, to the other side, then worked, and the handle sunk as it gets deeper in. After the sawing is completed, the divided piece of bone must be freed and removed through the inner wound; in doing which the tendons of the m. tibialis posticus and of the m. flexor quartus digitorum longus must be avoided. The chiseled end of the splint-bone must be made to correspond to the shin-bone. If the disease have at- tacked the astragalus, all that part of the bone which is affected must be carefully chiseled away, so as not to leave a cut surface, which will prevent the new connexion between it and the shin-bone. (a) Above cited, p. 91.—Roux, above cited, p. 53. OF EXCISION OF THE ANKLE-JOINT. 743 After the wound has been cleansed and the bleeding stanched, each angle of the flaps is to be fastened with a suture, the knee half bent, the leg placed on its outer side, supported on a chaff pillow, and the wound covered with lint, compresses, and a Scultetus's bandage. Jaeger (a) has modified Moreau's method in the following manner. The lon- gitudinal cut of three inches is sufficient, but the transverse cut must be larger, about two inches and a half, as he now only meddles with the skin, and therefore passes over the tendon of the m. peroneus iertius without injuring it. The L shaped flap is dissected upwards, the external malleolar sheath opened, and both tendons and muscles dissected from the back of the splint-bone. The anterior, posterior and ex- ternal ligaments of the splint-bone are then cut away from that bone, the joint opened, and next the ligaments between the splint-and shin-bones, cut through, and the splint-bone divided above the diseased part with a chain saw, or in want of this, nipped off with the sharp bone-nippers; the outer ankle is then grasped with the fingers of the left hand or with forceps, pulled up and completely separated from its hind connexions with the shin-bone; and whatever splinters remain must be taken away also. The joint-surfaces of the shin-bone and astragalus being now exposed, if they be found healthy the operation is concluded ; but if otherwise, the extirpa- tion of the inner ankle must be proceeded with. For this purpose the longitudinal cut of three inches must be carried through the middle of the inner ankle, and the transverse one forward an inch and a half, it may also be lengthened backwards so that a J. shaped cut may be formed. The flap is now, together with the fascia, to be dissected off close to the bone, the internal malleolar sheath opened, and all the parts on the back of the shin-bone, together with the nerves and vessels, carefully separated from the bone; and also on its front, the deltoid ligament cut through and the whole joint opened, in doing which the foot is again turned and the wound en- tered from the outside. After opening the joint, the inner ankle must be dislocated and brought out of the wound, by which the foot is turned at a right angle and rests on its sole. The shin-bone is then sawn off above the ankle with a small bow-saw. If the upper part of the astragalus be diseased, a small knife-saw may be passed into the wound, with which it may be sawn off, or what is better it may be removed with the file. Throughout the whole of this operation no tendon need be wounded, and the front of the annular ligament not cut through, as otherwise the antagonism to the Achilles' tendon is taken away, and the operation is without satisfactory result (b). Mulder (c) removed the lower end of a carious splint-bone, in doing which he first took off the fungous growth from the bone, then removed a portion of healthy bone together with the diseased part, enlarged the wound downwards with the scalpel below the ankle, separated it from the interosseous ligament, and through the cap- sular ligament and removed the lower part of the splint-bone. Kerst (d) also pro- ceeded in nearly the same manner. [Excision of the Ankle-Joint is most commonly employed in English practice, for compound dislocation, in which the shin- and splint-bones, both usually, broken from their malleolar processes, which still remain attached to the astragalus, are protruded through the skin wound, and either cannot be drawn back into their place, or if they can, are held to excite such irritation by the inflammation of their synovial coverinc, as to endanger the life of the patient, or at best to render the cure very te- dious and exhausting. Under such circumstances, Astley Cooper strongly advised the protruded ends of the bones should be sawn off, and afterwards the shaft re- placed. If the patient? be young, there is generally little shortening of the limb even after the removal of ha-lf an inch or an inch of hone; and in the cases I have seen, anchylosis generally has not followed.—j. f. s.] 2840. After decapitation of the splint-bone the wound is to be lightly filled with oiled lint, the flaps fastened with some sticking plaster, the wound covered with lint, and the foot laid upon its outside with the knee (a) Above cited, p. 688. Beitrage zur Natur und Heilkunde, vol. ii. (b) Weber, B.,Zwei Resectionen im Fuss- p. 142. 1827. gelenke; in Friedkrich und Hessklbach's (c) Wachter, above cited. (d) Heelkundige Mengelingen. Utrecht, 1835.—Hamburg.Zeitsch.,vol.ii. parti?.p. 169. 744 OF EXCISION OF THE METACARPAL JOINTS, ETC. half-bent, upon a chaff pillow covered with lint and compresses, and the usual dressings. After decapitation of both bones, their ends must be brought near to the heel, the longitudinal and transverse wounds brought together with sutures, the angle of the wound left open for the escape of the discharge, the wound covered with lint, and a bandage applied in the usual way. According to Moreau and Boyer, during the treatment the foot should be steadied! by a foot-board attached to two side splints on the leg, to keep it immovable. This Jaeger thinks onlybf consequence if the shin- bone be left. In his case he dislocated both bones on the outside and placed them in Sharp's concave splints on Sauter's swing till he ap- plied the common splints. During the cure the ends of the bones approach each other, and become firmly united; in consequence of which, in many cases, when the astragalus is left entire motion is destroyed. This firm connexion is only first produced in the space of a year, from the use of a limb. After the healing of the wound Sharp's splints must be applied. So long as the foot is not firm, the patient must walk with a crutch, till at last he can be fitted with a heel, corresponding with the length of the lost bone (Jaegbtr.) VIL-^lOF EXCISION OF THE JOINTS OF THE METACARPUS AND METATARSUS. (Excisio Metacarpiet Metatarsi, Lat.; Ausrottung in den Gelenken der Miltelhand-und Mitteffuessknochen, Germ.; Resection des Mitacarpiens et des Metaiarsiens, Fr.) 2841. In the metacarpal and metatarsal bones, decapitation has the great advantage of preserving the joint. The decapitation of the meta- carpal and metatarsal bones is performed with a longitudinal cut carried to the extent of the portion of bone to be removed, the sheath of the tendon covering it opened, laid aside, the muscles" separated from the sides of the bone,H and the joint opened from above. The chain saw is then introduced by means of a small semicircular needle, or a narrow finger-saw is passed beneath the bone which it divides, or it is cut off with Liston's cutting forceps, or with the osteotome, lifted up, and whilst turned forwards or backwards, is completely separated from the soft parts. After the wound has been cleansed, a connecting bandage is put on and cold applications made. To keep the bone in proper position, it is ne- cessary to fasten a narrow pad, a foot long, on both sidesa or upon the dorsal and plantar surface of t\e foremost phalanx with sticking plaster, and by drawing back equally the ends of the long pad the bones are kept together, and the ends of the pad are fastened upon the wrist or ankle- joint with plaster. On the foot, with a foot-board, a pad of lint and some straps of plaster are commonly used, passed over the end of the phalanx, and the ends brought over and fastened on the foot. In old dislocations of the metacarpal bone of the thumb, decapitation is often indi- cated, and frequently performed. Textor removed the end of the middle metacar- pal bone and the os magnum in a case of caries., Textor, Kramer, and Roux have also decapitated metatarsal bones; and Fricke has obtained most successful results therefrom (a). (a) Gernet, Ueher Resectionen; in Hamburg. Zeitsch,, vol, iii. part iv. L 745 ] VIIL—OF EXCISION OF THE LOWER JAW. (Excisio Maxillae Inferioris,.Lat.; Ausrottung des Unterkiefers, Germ.; Resection de-la Machoire Infirieure, Fr.) 2842. Excision, Decapitation, and even the total Extirpation of the Lower Jaw, may beindicated by various kinds of disease (1). First, On account of cancerous degeneration, which has extended from the lips to the bone, or when the-cancer has arisen in the bone itself. Second, On account of osteosteatoma', osteosarcoma, spina ventosa, or fungojd degene- ration of the jaw. Third, On account of deep-seated caries. Fourth, On account of exostoses, which cannot be removed at their base. And, Fifth, on account of want of union of fractures of the lower jaw. Ac- cording to the difference of the seat and' extent of the disease, excision of the middle part, the-chin, or of the sides^ with or without the removal of the processes at the same time, or even the extirpation of. the whole lower jaw-bone, may be required'. That this operation should have a favourable result, the skin must be sound to such extent that it can properly cover the place of the removed part, and swelling of the- neighbouring1 glands^ or the signs of general can- cerous dyscrasy must not in general forbid every operation. The hope of a favourable issue-is greatest in sarcomatous degeneration of The jaw, but it is doubtful in all cancerous affections. Only, under the above-stated'conditions of the skin and glands can cancerous dege- neration be considered as indicating this operation; but they are very rare ; and so far is Jaeger's (a) opinion correct, who although the cases of Dupuytren, von Graefe, Fricke, and others favour undertaking this operation for eancer, considers that in general it is contraindicated. Necrosis of the lower-jaw, if unaccompanied with caries, must not be held to indicate the operation ; for with proper treatment the dead piece>of bone will be thrown off (2) or may be removed j for I'have in several instances taken away- more than half and in one case nearly the whole lower-jaw. [(1) As will be presently seen, Deadrick was the first who, in 1810, cut away the side of the lower jaw ; in 1812, Dupuytren sawed' off a large portion of the front of the jaw ;■ in 1816, Anthony White- removed half a necrosed jaw from the socket; in 1818, Astley Cooper sawed off the projecting part of the chin; in 1821, Graefe removed the front of the jaw, and in the same year, one-half of the lower jaw, which he exarticulated, and-the patient lived : Mott's first operation, in which half the jaw was removed, by-sawing through the chin and across the ascending branch, was performed in March, 1822; his second, in which he exarticulated one- half, in May, 1822; died on the evening of the fourth day. Cusack removed the left half of the jaw in 1825, first sawing through the horizontal and afterwards the ascending branch, an mylo-hyoideus and genio-hyoideus if the head,be drawn backhand therefore, if the head be bowed towards the chest, the tongue resumes, its proper place and the choking ceases, as I noticed: in a case in which I removed the; fore part of the jaw., in front «f the m>.masseteres, on both OF EXCISION OF THE LOWER JAW. 747 sides (a). Lallemand, in one case, opened the windpipe, and Delpech fixed the tongue with a hook. If a large piece of the jaw-bone be removed, it may be convenient to introduce some lint between the ends of the bone, to prevent the soft parts dropping in. [Dupuytren (b) according to his own statement, performed this operation, on 30th of November, 1812, in a case of cancerous tumour, extending from the right cuspid tooth to the left branch of the jaw-bone; the part thus described was three times its natural size*. The jaw was removed by sawing it through an inch in front of each of its angles. The patient suffered little after the operation ; on the twenty- seventh day he was able to drive one of his cabriolets; on the thirtieth some small portions of bone came away; and fifteen days after, his cure was completed. Graefe (c) removed, in the early part of 1821, from a woman aged forty, the front of the lower jaw, which had" become involved in cancerous disease, sawing through it on each side ; and the patient recovered completely in the course of five weeks. The case in which Astley Cooper (d) operated, was a fungous medullary exos- tosis on the chin. He eut down through the skin on each side of the tumour, and then sawed through the healthy part of the jaw, cutting off the prominence of the ehin, but without meddling with the alveolar processes so that the arch of the jaw re- mained perfect. The operation was performed, I believe, in 181S, but certainly .not later than in the beginning of the year following, and the woman did well. Al- though the operation was not of such importance as those just mentioned; yet as it was, so far as. I am aware, the first upon the jaw performed in London, I have thought it right to notice it. The preparation is. in. St. Thomas's Museum.—*j. f. s.] . 2844. In removing a portion of the side of the lower jaw without the condyle the cut for laying bare the bone must be made in different ways, according to the sise and seat of the bony tumour, sometimes from the corner of the mouth to below the edge of the jaw ; still better is an ob- lique cut from the corner of the mouth to the place where the bone is to be cut through, or from the corner of the mouth in form of a _J cut; in very large swellings a J cut; when the skin is much diseased, two elliptical cuts from, the corner of the mouth ; or if the entire side with the angle or part of the ascending branch is to be removed, then a | I. cut or the like. The flaps are now to be separated close to the bone, held back by the assistants, and the soft parts on the inside of the bone care- fully detached, the knife being carried close to the bone where it is to be sawn through. After the compress has been introduced, the bone is to be sawn through, first in front, and then the piece, grasped with the left hand, must be pressed downwards and outwards^and with the knife car- ried close to. the bone all the remaining soft parts carefully separated to the extent of the tumour behind; the compress is then introduced, the bone held in this position by an assistant and eui off. The sawn-out bone is now drawn outwards and completely separated from the soft parts forming the bottom, of the mouth, the bistoury being kept with the greatest care close to the bone. After stanching the bleeedin^,the wound must be brought together at the lip with the twisted, and on the cheek with the interrupted suture and; supported with sticking plaster. Sawing through the bone first in front is-most convenient, because, the operator can then draw it to him, and turn it down. If the soft parts be divided from the whole inside of the bone before it is sawn through, at the back part, the sawing is accom- (a) Chelius, Ueber Resection des. Unter- (c) Jahresbericht des chirurgisch-augen- kiefers; in Heidelberg. Medic. Annalen, vol. arztlichen Institute zu,Berlin.—Graefe und i. part. i. von Walther's Journal, vol. iii. p. 256. 1822. ' (6) Clinical Lecture translated; in Lancet, (d) Cooper and Travers's Surgical Essays 1833-34 ; vol. i. p. 56. part i. p. 179. 1818. 748 OF INCISION OF THE LOWER JAW. panied with greater difficulty than if the soft parts be divided afterwards, especially if the tumour be of large size. Since Deadrick and Dupuytren first performed resection of the lower jaw, the operation has been very frequently performed and with'much success. [Deadrick (a) of Rogersville, Tennessee, is justly entitled to the merit of having first, in 1810, amputated a portion of the jaw of a child of fourteen, who had a tu- mour occupying the left side of the lower jaw. " An incision was commenced under the zygomatic process; and continued on the tumour, in the direction of the bone, to nearly an inch beyondUhe centre of theehin. A second" incision was begun about midway, at right angles with the first, and extending a short distance down the neck. The integuments were now separated from their connexion with the tumour, and the bone was sawed off immediately at the angle and centre of the chin. The wound was united in the usual manner, and the boy had a speedy and' happy re- covery." Mott's first operation was in 1821 (b), in which after having sawn through the chin, and after the maxilla inferior had been laid bare-just below its division into two processes, and it appeared sound, he " with a fine saw, made for the purpose, smaller and, more convex than Hey's, began to saw through the bone obliquely, downwards and backward's and finished with one* less convex." This was for osteosarcoma. It is claimed' for Wardrop (c), that he first, in England, in March, 1827, ampu- tated the lower jaw, in a case of exostosis; the jaw was cut through first behind the last molar tooth, and then between the middle two incisive teeth* The following are accounts of some of these operations:.— Klein; in Neue Chiron von Textor, vol. i. part. ii. p. 345. M'Clellan, in Medical Review, and Anal. Journal. Philadelphia, 1824. Delpech; in Revue Medicale, vol. iv. p. S. 1824. Lallemand; in Journal Universel des Sciences Medicates, voh xxviii. p. 340. Dybeck ; in Froriep's Notizen, vol. viii. p. 95. Schuster; in same, p. 304. Behre, G., Bemerkungen iiber die theilweise Excision und Exarticulation des Unterkiefers, nebst den zer Geschichte dieser Operation gehorigen Fallen; in Rust's Magazin, voh xxiii. part iii. p. 387. Meyer, J. C, Dissert de Exstirpatione partiumidegeneratarum Maxillae Inferioris. Berol., 1624. 4to. Koecker, An Essay on the Diseases of the Jaws and their Treatment; with Ob- servations on the Amputation of a part or the whole of the Inferior Maxilla. Lon- don, 1828. Delbech^ Memorial des Hopitaux du Midi et de la Clinique- de Montpellier. 1829; p. 123. Jaeger; in Rust's Handbuch der Chirurgie, vol. vi.p. 496. Boyer, Memoire sur l'Amputation de l'Os Maxillaire Inferieur; in Journal Com- plement, du Diet, des Sciences Medicates, cah. 174. Dupuytren, Logons 0rales de la*Clinique ohrrurgicale, vol. iv. p. 625". [Report of a Committee upon the subject of Osteosarcoma of the Lower Jaw, to the Medical Society of N. York. 1830;] 2845. Excision of the lower jawr^together with the removal of its con- dyle (Exarticulatio Maxilla Inferioris) requires a different mode of making, the cut,, according to the different condition of the tumour and of the skin over it. The cut may be made from, the corner of the mouth over the swelling, to the front of the ear, and the condyle of the jaw (Mott, Schindler) ; or to the hinder ed£e of the branch of the jaw, a second, cut from the beginning, to the end of, the first cut, circumscribing the diseased skin, and thence in an oblique direction to the condyle (a) Amer. Med: Recorder^ vol. vi. p. Recorder, Jan., 1822. This case is given at 516. 1826. • length in Gibson's Institutes and Practice.of (6) New York Medical and Physical Surgery, vol. ii. p. 28. Philadelphia, 1827. Journal, vol. i. p. 386.—American Medical (e) Lancet, voL xii. p. 27. 1626-27. OF EXCISION OF THE LOWER JAW. 749 (von Graefe); or in very large swellings, and great disease of the skin, two elliptical cuts, of which the one passes in the direction of the base and branch of the jaw to the condyle, and the other upwards, by which the coronoid process is laid bare, the m. temporalis divided, and the joint opened at its fore part (Syme) ; or in shape of an oblong, four-cor- nered flap, from the corner of the mouth to the neighbourhood of the ex- ternal maxillary artery, from thence at a distance of a quarter of an inch from the edge of the bone to the angle of the lower jaw, and then up- wards to the front of the joint an inch distant from the ear (Jaeger). The flaps are now separated from the bone, and in doing this, injury of the Stenonian duct and parotid gland, must be avoided. The m. mas- seter is cut through at the base of the lower jaw, the m. buccinator sepa- rated from the outer surface, and both together with the parotid gland raised up till the joint is laid bare. The soft parts are now separated from the inside of the bone, and the bone sawn through at its fore part, as already described, and the division of the soft parts from its inside completed. The bone is then depressed as much as possible, for the purpose of disengaging the coronoid process from the zygomatic arch, and rendering the m. temporalis tense. The condyle is thus thrown completely on the articular tubercle, so that there is perfect dislocation. The knife is now carried above the coronoid process and the tendon of the temporal muscle cut off, then, over the semilunar notch between the two processes, and whilst the point of the knife is kept as close as possi- ble to the condyle, the internal pterygoid muscle is divided. The jaw can now be further dislocated, which is so much the better, as thereby the condyle is still further separated from the vessels. Continuing close to the neck of the condyles, the stretched capsular ligament is cut into in front. The assistant pressing the jaw still more downwards, and moving it backwards, the condyle next becomes visible, and the knife being car- ried over it to the hinder ligament, cuts through it, whilst the edge of the knife is kept close to the bone, and the point not carried forward. After the bleeding vessels have been tied, the wound is brought together and managed as in resection of the jaw. von Graefe (a), Mott (b), Langenbeck (c), and Jaeger (e?) operate in this way which is generally to be considered as the most safe and convenient. Cusack (e) considers it better, when in large tumours it is not thought right to lay hold of the bone sawn through in front, to grasp it between the angle and the condyle with strong forceps, and to press the condyle against the front of the capsular ligament, penetrate the joint, enlarge the opening with the button-ended bistoury, thrust the condyle out, and separate its- other connexions with the capsule as well as with the external pterygoid muscle. Jaeger speaks very decidedly against this sawing through the bone above its angle, and the after removal of the processes; in one case where the bone was com- pletely separated from its branch, it was impossible to pull forward the remainder of the bone so as to separate the tendon of the temporal muscle from the coronoid process. The joint must be opened in front, and by pulling forwards the head of the bone with a strong hook, it must be gradually separated from its hinder connexions. Cutting through the tendon of the temporal muscle is then effected so easily that he advises the condyle should always be first set free. Holding the stump of the bone is especially difficult; and according to his experiments on the dead body, he (a) Journal, vol. iii. part ii. p. 257. seclione. Gotting®, 1829. (b) Above cited. (d) Above cited, p. 605. (c) Tiensch, Dissert, de Osteosarcomate (e) Dublin Hospital Reports, vol. iv. partiali Maxillae inferioris, deque hujus Re- p. 37. I 750 OF EXCISION OF THE LOWER JAW. considers sawing through the branch is difficult, and the exarticulation not rendered easier by doing so. .... On the other hand, Schindler (a) justly observes that the exarticulation may be effected with complete certainty without sawing through the jaw at its hinder end, when the tumour of the bone is not of great size; but that every large tumour renders its removal indispensable, else the exarticulation may become unnecessarily difficult, and only be completed with some danger. In his case the swelling was so large, that even after removing its upper part, it was almost impossible to pene- trate the joint, and effect the disarticulation with safety. He found no difficulty in the division of the diseased bone, and could grasp conveniently the remaining piece, although only an inch and a quarter long, with the fingers of his left hand, draw it well towards him, and easily dislocate the condyle. The patient recovered. Mott, von Graefe, and Dzondi have held the previous tying the common caro- tid artery necessary, but experience has shown that this is superfluous, is dangerous, and no safeguard against bleeding (Jaeger, Schindler.) If the removal of the entire jaw be necessary, the bone must be sawn through in the middle, and the extirpation performed on either side, as already directed (Dupuy- tren), (b). [Samuel Cooper (c), after mentioning that Wepfer quotes a case of amputation of the lower jaw, which had occurred in his time, says, " Mr. Anthony White, Surgeon to the Westminster Hospital, removed at Cambridge a considerable portion of the bone for an osteosarcoma many years ago. Unfortunately the case was not published, so that the revival and execution of the operation are generally referred to Dupuytren, who in 1812 performed his earliest excision of the lower jaw-bone." (p. 275.) In consequence of Samuel Cooper's statement, I was induced to inquire of my friend White, for information in regard to his operation on the lower jaw, and I have much pleasure in communicating to the profession the following particulars, with which he has kindly furnished me, from which it appears, that he actually dis- articulated the lower jaw-bone from its socket five years before Graefe, and six years previous to Mott. The following is White's Case.—" In the summer of 1816 I was requested to see a man, named Litchfield, residing in the town of Cambridge, who for upwards of three years had been miserably affected with a disease of the lower jaw, occupying the entire left cheek, and wholly incapacitating him from opening his mouth. He states, that in attempt- ing to bridle his master's horse, the animal, by an unexpected jerk of the head, struck him a violent blow on the under jaw"; that the part for a few weeks remained pain- ful and swollen, and although after a lapse of time, the enlargement occasioned by the injury had considerably diminished, yet a slight preternatural fulness and occa- sional pain remained. Some months after a rigidity in the motions of the jaw at its joints succeeded, accompanied with a slowly accumulating and hard enlargement ex- tending from the ear nearly to the chin.. By degrees, the jaw wholly lost its powers of motion, and finally the teeth became firmly fixed on those of the upper jaw, which was followed by the formation of small abscesses externally and internally. Thin fluidiS, as milk and broths, have been for the last two years his only nourishment; and during this time he has been compelled to sleep in an almost erect posture, on account of a perpetual internal discharge which, whilst he was in the horizontal pos- ture, poured down his throat, producing, when he was about to sleep, a constant alarm of suffocation. The whole cheek, from the ear to the orbit, ranging down the side of the nose to the angle of the mouth, and thence to the under part of the chin, and again upwards to behind the lobe of the ear, presented one large irregular mass of scirrhus-feeYwg growth, studded with many sinuses, the windings of which were difficult to trace. The eye was so considerably projected from the socket, that the eyelids could cover but a very small portion of the globe, and such was the rigid thickening of the cheek, that much difficulty was experienced in introducing the finger within it for the purpose of examining the disease internally. I discovered, however, a point of the jaw-bone bare within the cheek, and by pressure, perceiving an obscure motion of its whole side, I was induced to believe that the bone was (a) von Graefk und von Walther's Journal vol. xvii. p. 568. 1831. (b) Above cited. (c) Dictionary of Practical Surgery. Edition of 1838. OF EXCISION OF THE LOWER JAW. 751 either carious or dead throughout its whole extent, although there had not been at any time the least exfoliation through either of the many sinuses. By repeated exami- nations, 1 was fully convinced of this impression being correct; and I afterwards by firmly grasping the chin and cheek, and then attempting to produce a lateral motion, distinctly perceived a grating sensation of the condyloid process on the skull. I now contemplated, if there was a possibility of removing the entire side of the bone, the cause and continuance of the extensive mischief, that the opposite joint When disentangled of its still adhering dead neighbour, might be restored to its important duties. I also considered that from the long-existing thickened and altered state of the left cheek and surrounding parts, little was to be feared from haemorrhage, as the vessels were likely to have become obliterated, and if my conjecture was well found- ed, as to the death of the bone, the large artery which runs along the maxillary canal must also have perished. " A few weeks elapsed before I was again able to visit Cambridge, and the pa- tient being then in the same condition, and the operation having been proposed and explained to him being very desirous it should be done, I proceeded to its perform- ance with the assistance of the present Professor of Comparative Anatomy in the University, Dr. Clarke and Mr. Headlev, a practitioner in the town, to whose assistance I am much indebted. Operation.—" The patient's head having been firmly fixed on the side upon a pillow, and my first object being to expose the bone, I began an incision, as near as I could guess, from the root of the zygomatic process of the temporal bone, and car- ried it obliquely downwards and forwards considerably beyond the angle of the jaw towards the chin. Inconsequence of the thickened state of the integuments, the depth of the wound was very great before I could reach the bone; but having made sufficient room for the introduction of my finger, I was gratified in finding the bone without its periosteum; and with a curved bistoury, the incision was speedily finished upwards to the zygomatic arch, and downwards beyond the edge of the lower jaw opposite the third molar tooth. With the handle of a scalpel and the blade of a pair of forceps, sufficient separation was made to allow the point of the fore-finger to range freely and to separate the surrounding diseased structure from the enclosed bone. By thus doing, I was enabled to slide the fore-finger within the ascending branch of the jaw-bone into the mouth, and the thumb under its angle. On endeavouring to ascertain the degree of fixture whieh the bone might have, I discovered a complete fissure of separation in an oblique direction from where the finger entered the mouth towards the chin< through the entire jaw, but the bone was immovable at the temporo-maxillary articulation. After repeated unsuccessful at- tempts at dislodging the condyle, I determined to saw vertically through the ascend- ing branch of the bone, between the condyloid and coronoid processes, calculating that the separation would be more easily effected by bringing it away in two or more pieces. I therefore applied a small straight and narrow saw upon this part with ex- cellent effect, as its end passed with facility, in the required movements, under the zygomatic arch; and Hey's saw was very useful in cutting through the thicker part towards the angle. I now with a pair of strong forceps, grasped the lower edge of the divided bone, and easily dislodged the coronoid process, and I removed it to- gether with the lower part of this portion. Having thus gained considerable room, the separation of the condyle and remaining portion of the ascending branch became quite easy. The bone, although dead, retained its form unaltered. The glenoid i» cavity of the temporal bone was by the finger discovered to be denuded and rough. The carotid artery was now felt distinctly pulsating, the finger being enabled to rest upon it. One great object having been thus attained, we were anxious to ascertain the state of the other articulation, and were highly gratified in finding that a slight degree of motion existed which gradually became increased. Some few months after, I had the satisfaction of finding the wound and sinuses healed; the swelling and its warty character subsided ; the globe of the eye retired into its socket, and the motions of the jaw restored. The patient lived several years after." Graefe (a), in 1821, exarticulated one side of the lower jaw of a young woman, having previously tied the carotid artery, for hydrostosis carcinomatodes, which had destroyed more than half the jaw, and on the left side reached up to the condyle. The swelling extended far back, and pressed on the important vessels and nerves of (a) Above cited, p. 257. 752 OF EXCISION OF THE LOWER JAW. the neck. Internally it thrust the tongue against the right cheek, and so completely filled the mouth, that latterly the patient was able to swallow even fluids with the greatest effort, could only utter words indistinctly, and breathe with extreme difficulty. As death by hunger or choking was all but certain, it was determined to run the risk of operating, in hope of saving her. The left common carotid artery, which was very large and pulsated strongly, was carefully tied, and immediately the pulsation in the temporal and facial arteries ceased. A cut was then made from the angle of the mouth to the hinder edge of the jaw; a second, which included the diseased mass, was carried from the front point of the first cut to its hind end ; and a third, begin- ning at this latter point, was carried upwards in the direction of the condyloid pro- cess, above the joint and nearly to the ear. The outer surface first, and then the inner surface of the diseased half of the bone, were freed from the soft parts con- tinuing the separation to the chin, and then, a piece of leather having been introduced, thejaw was cut through at the chin, and afterwards exarticulated. When the bleed- ing had been stanched, and the corner of the mouth carefully fixed, a simple dress- ing was applied. Up to the eighth day she was perfectly well, could speak loud and distinctly, ate, drank, and could press the remaining half of the lower firmly against the upper jaw; but on this day, after a violent thunder-storm in the previous night, she was suddenly and severely attacked with apoplexy, which gradually sub- sided into fatuity and speechlessness, accompanied with hemiplegia. By degrees the mental powers returned ; the lameness of the right foot ceased entirely after some time ; the wound healed completely under very simple treatment; the paralytic state of the right arm and tongue began to lessen more and more; she eats any food, is well nourished, is quite capable of walking to some distance, and is delighted with her condition, as she improves from month to month. Mott (a) exarticulated, on \bth May, 1822, the right side of the jaw of a young man of eighteen, affected with osteosarcoma, which had existed eight years, had com- menced at the molar teeth, filled the whole mouth and spread as far as the first bi- cuspid tooth on the opposite side. He first made a semilunar cut through the integu- ments from the lobe of the ear to the chin; sawed through the jaw at the second bi- cuspid tooth on the left side, and then exarticulated thejaw on the right side. The swelling weighed twenty-two ounces, and was as large as the head of a full-grown foetus. The patient went on well, and on the morning of the fourth day two-thirds of the wound had healed ; but on the evening of that day he died. On examination, the lungs were found violently inflamed ; the anterior mediastinum contained a quantity of yellow lymph, nearly of the consistence of pus; the pericardium held a pint of yellow serum, and the pleura was enormously thickened. The inference drawn was—"Hence it appears clear, that the patient died of disease of the lungs which had no connexion with the operation." To which the editor in Graefe's journal appends 1 with which most readers will probably agree. Cusack (b) in his excellent Report of the Amputation of portions of the Lower • Jaw, shows, that tying the carotid artery, as had been done by Graefe and Mott to guard against bleeding from wounding the external carotid or internal maxillary artery in exarticulation of the lower jaw, is unnecessary. " Neither of these ar- teries," he observes, "is in immediate contact with the jaw. The internal maxil- lary, which would appear more exposed to danger, inclines backwards in its passage behind the neck of the condyle being distant about a quarter of an inch from the bone;—the natural structure of the joint allows this distance between the artery and articulation to be still further increased ; so that by sawing the bone through at any point and separating the attachment of the temporal muscle, the capsular ligament may be opened anteriorly, the condyle dislocated, and the jaw disengaged, without endangering any vessel of consequence." (pp. 13, 14.) Cusack is the first surgeon who, in this country, exarticulated the jaw, which operation he performed thrice in 1825 and once in 1826. After having separated the soft parts, and drawn as many teeth as were necessary, he cut through the jaw at the chin, and after having sawed across the ascending branch, " the cut extremity was seized in a strong pair of for- ceps, and the attachment of the temporal muscle having been divided, this fragment (a) New York Med. and Phys. Journal, been able to see either of the American vol. ii. p. 401.—American Medical Recorder, Journals quoted, nor to find it in any other vol. v. 1822.—Graefe und von Walther's Journal of the time, American or English. Journal, vol. iv. p. 547. I have been com. —j. f. s. pelled to use Graefe's report not having (6; Dublin Hospital Reports, vol. iv. 1827. OF RESECTION OF THE UPPER JAW. 753 of bone, was nsed as a lever to press the condyle against the anterior and external part of the capsular ligament, which was thus put on the stretch. An opening having been made into the capsule at this part, the disengagement of the condyle was effected by a blunt-pointed bistoury, carried cautiously round the joint, and di- viding the attachment of the external pterygoid muscle. This second section of the bone may appear, at first view, unnecessary, when the jaw is to be removed from the articulation; but the body of the bone is, in general, so much disorganized, or so deeply involved in the tumour, that it could not be used as a lever to press the condyle against the capsule; a case might occur, however, in which the second division of the bone would be unnecessary." (p. 37.) As has been already no- ticed by Chelius, Jaeger objects to sawing through the ascending branch of the jaw, whilst, on the other hand, Schindler supports it. This operation has been repeatedly performed in England and Scotland without either previously tying the carotid artery or sawing across the ascending branch of the jaw. Liston (a) recommends partially sawing through the bone at the chin and then by placing the cutting forceps in the notch to clip it through. He observes also, in regard to stanching the bleeding, that " much time and trotble will often be saved by at once looking for and securing the common trunk of the temporal and internal maxillary arteries as they emerge from under the border of the posterior belly of the dtgastric muscle." (p. 318.) Upon this subject the following writers may also be consulted :— Gierl. Einige Bemerkungen fiber die Resection und Exarticulation des Unter- kiefers; in Textor's Neuer Chiron, vol. ii. part ii. p. 345. Lambert, Dissert, sistens casum Exsectionis dimidiae Maxillae Inferioris ex ar- ticulo, praevia subligatiene carotidis. Aal., 1826. Jaeger; in Rust's Handbuch der Chirurgie, vols. v. and vi.; and in Handwor- terbuch der Chirurgie, Article Reseclio Orsium, which treats very fully of the deca- pitation and resection of the several bones. [Perry (b) had a case of necrosis of the whole lower jaw, the front of which he removed by making an incision from the front of one masseter muscle to the other, dividing the bone on each side with the saw and nippers. On the next day the right ascending branch which had dropped a little, was removed without difficulty; and three weeks after, the left, which adhered rather more firmly.] Sixth Section.—OF RESECTION OR EXCISION IN THE CONTINUITY OF BONES. (Reseclio Ossium in continuitaie, Lat.; Resection in der Continuitdt der Knochen, Germ.; Resection, Fr.) I.—Of Resection of the Upper Jaw. 2846. Resection of the Upper Jaw, performed at an early period for various diseases in the Highmorian cavity, with chisel and hammer, or with the sickle-shaped knife (Desault), has been in modern times spe- cially brought into notice by Dupuytren in 1819, and since then per- formed by many surgeons. It is indicated jn caries, fungous degenera- tion of the alveolar process and of the upper jaw, in osteosteatoma and osteosarcoma, in medullary fungus, and polypus degeneration of the maxillary cavity. The performance of this operation is difficult, the shock very great; violent bleeding, and spreading of the inflammation to the brain may occur; and in malignant degeneration, the permanent benefit of the operation is very doubtful on account of the frequent re- currence of the disease. (a) Practical Surgery> (b) Med.-Chir. Trans., vol. xxi. p. 290. 1838. Vol. hi.—64 754 OF RESECTION [Gensoul (a) shows that Dupuytren did not remove the whole jaw in 1819, but only followed Jourdain and Desault's method of scooping out the contents of the antrum; and in regard to Sanson and Pinel Grandchamp, who were stated to have witnessed this operation, he says:—" I saw these two practitioners for the purpose of knowing what method had really been adopted. Sanson informed me that he had no knowledge of the fact of an entire removal of the superior maxillary bone; that he knew only of the operation performed in 1820, which was similar to De- sault's, and of one other in the year 1824; and that in the latter case, a large piece of the edge of the alveolar process had been removed with a small saw. Pinel Grandchamp said he had witnessed the two operations mentioned by San- son, but he had never heard say that Dupuytren had even thought of removing the whole superior maxillary bone." (p. 10.) But neither Dupuytren nor Desault, nor Garengeot, nor Jourdain, were the original performers even of this scooping operation, for Akoluthus (b) a physician at Breslau, being consulted in 1693, by a woman who had a tumour on the jaw, which followed the extraction of a tooth, enlarged the mouth with a cut, removed part of the swelling, togather with four teeth, but not being able at once to get com- pletely round it, he attacked it several times, at intervals of a few days, sometimes with cutting instruments, and sometimes with the actual cautery, and at last suc- ceeded in curing his patient. • The nearest approach to a total removal of the whole superior maxillary bone, if indeed the entire bone were not removed, is detailed in the following interesting and important case, which was operated on by Dr. Thomas White, the father of Charles White, to whom reference has been recently made. He relates it among his own Cases in Surgery, and I am not aware of any other case in which such ex- tensive mischief had been done by disease of the antrum, and yet the patient had recovered. The patient was a woman " afflicted with a tumour betwixt the zygomatic pro- cess and'thenose, arising from the lower part of the orbit of the left eye. It pressed the nostrils to one side, so as to stop the passage of the air through them, and thrust the eye out of its orbit, so that it lay on the left temple, yet, though thus distorted, it still performed its office. The tumour occupied the greatest part of the left side of the face, extending from the lower part of the upper jaw, to the top of the forehead, and from the farthest part of the left temple to the external canlhus of the eye. It had an unusual and unequal bony hardness. It was of a dusky livid colour, with varicose veins on the surface, and there was a soft tubercle projecting near the nose, where nature had endeavoured in vain to relieve herself." For the removal of this disease, he continues, " I began with a semicircular incision below the dislocated eye, in order to preserve that organ, and as much as possible of the orbicular mus- cle ; then carrying the incision round the external part of the tumour, I brought it to the bottom of it, and then ascended to the place where I began, taking care not to injure the left wing of the nose. After taking away the external part of the tumour, which was separated in the middle by an imperfect suppuration, there appeared a large quantity of matter, like rotten cheese, in part covered by a bony substance, which, however, was so carious, as to be easily broken through. I scooped away abun- dance of this matter, with a great many fragments of rotten bones. Upon cleansing the wound from blood and filth, with a sponge, I found the left bone of the nose, and the zygomatic process carious, and easily removed them with an elevator. There were no remains of the bones composing the orbit of the eye, which were plainly destroyed by the same disease. The optic nerve was denuded as far as the dura mater; and the dura mater and pulsation of the vessels of the brain were apparent to the eye and touch. The left superior maxillary hone, in the sinus of which this disease had its origin, and remained a long time concealed, was surprisingly dis- tended, and in some places became carious; it had exfoliated from the lower part to the sockets of the teeth, which part was in like manner removed. I applied the actual cautery to the rest of the bones and putrified parts, taking care not to injure the eye and neighbouring parts, which were sound. The patient drew her breath through the wound, and was so incommoded by the foetid matter flowing into her throat, that she was obliged for several weeks to lie on her face to prevent suffoca- te) Ltttre Chirurgicale sur quelques Mala- (b) Ephemerid. Medico-physicarum, etc. dies graves du Sinus Maxillare et de l'Os Decad. iii. Ann. iv. Obs. 57. De horrenda. MaxUlare Inferieure. Paris, 1833. 8vo. Epulide. OF THE UPPER JAW. 755 tion. * * * The patient recovered. The eye returned to its place, and she enjoyed the perfect sight of it. The only inconvenience that remained was a con- stant discharge of mucus from the greater canthus of the eye, which I could never thoroughly cicatrize." (p. 135-38.) As regards the actual proposer of .the entire removal of thejaw, there can be no doubt, as will be presently shown, that in 1826 Lizars proposed it, recommending also that the carotid artery should be first tied. But Gensoul, seemingly without any knowledge of Lizar's proposition, performed the operation in the spring of 1827, and without previously tying the carotid or any other artery.—j. f. s.j 2847. The operation consists in the following acts:—flrst, cutting through the skin and muscles ; second, cutting out the diseased part of the jaw, and, third, bringing the wound together. The different mode of conducting, these acts depends especially upon the extent of disease in the bone. 2848. The patient is seated on a chair not very high, with his head resting on the breast of an assistant, who stands behind him. A cut is made from the corner of the mouth in a semicircular direction to the zygomatic arch ; or a _J or "f shaped cut through the cheek; or a cut from the inner corner of the eye, through the upper lip, above the cuspid tooth, from the middle of which, or perhaps a little above the base of the nose, a second cut is made to within four lines of the lobe of the ear, and then a third, which, beginning five or six lines to the outer side of the outer angle of the orbit, ends at the extremity of the second cut. (Gensoul.) For the purpose of avoiding palsy of that half of the face, by cutting through the facial nerve, as well also as to prevent a salivary fistula, by- wounding the Stenonian duct, the cut should be carried, according to Diffenbach, in the middle line of the face, instead of through the cheek. The flaps, formed in one of these ways, are separated from the bone to sufficient extent, any spouting vessels, especially the transverse facial and the facial arteries tied, and the flaps held aside by an assistant, with his fingers, or with a blunt hook. [There can be no doubt that Lizars is justly entitled to the credit of having, in 1826, proposed the entire removal of the superior maxillary. Speaking of "polypi or sarcomatous tumours which grow in the antrum," he says (a) —" All the cases that have come within my knowledge, (with the exception of one,) wherein these sarco- matous tumours have been removed by laying open the antrum, have either returned or terminated fatally. I am therefore decidedly of opinion, that unless we remove the whole diseased surface, which can only be done by taking away the entire supe- rior maxillary bone, we merely tamper with the disease, put our patient to excrucia- ting suffering, and ultimately to death. The inferior maxillary bone has now been nearly entirely removed for osteosarcoma with success, and I see no difficulty in ac- complishing the same with one of the superior maxillary. We secure the common carotid artery for other tumours of the face, and for aneurism by anastomosis, and why not do it for so loathsomeand fatal a disease as this 1 The steps or plan of the operation I would suggest for so fatal a disease, are, first, to secure the trunk of the common carotid artery of the affected side; next to make an incision through the cheek, from the angle of the mouth backwards or inwards to the masseter muscle, care- fully avoiding the parotid duct, then to divide the lining membrane of the mouth, and to separate the soft parts from the bone upwards to the floor of the orbit; thirdly, to detach the half of the velum palali from the palate bone. Having thus divested the bone to be removed of its soft coverings, the mesial incisive tooth of the affected side is to be removed; then the one superior maxillary bone to be separated from the other, at the mystachial and longitudinal palatine sutures, and also the one palate bone from the other, at the same palatine suture, as the latter bone also will require (a) A system of Anatomical Plates, &c, part ix. The Organs of Sense, &c, Edinburgh 1826. 8vo. 756 OF RESECTION to be removed either by the forceps of Mr. Liston, or a saw ; thirdly, the nasal process of the superior maxillary bone should be cut across with the forceps; fourthly, its malar process, where it joins the cheek-bone ; fifthly, the eye with its muscles and cellular cushion being carefully held up by a spatula, the floor of the orbit is to be cleared of its soft connexions, and the superior maxillary bone separated from the lachrymal and ethmoid bones, with a strong scalpel. The only objects now holding the diseased mass, are the pterygoid processes of the sphenoid bone with the ptery- goid muscles. These bony processes will readily yield by depressing or shaking the anterior part of the bone, or they may be divided by the forceps, and the muscles cut with the knife. The bone or bones are frequently so soft in this disease, as to be easily cut with a knife or scissors. After the bone with its diseased tumour has been removed, the flap is to be carefully replaced, and the wound in the cheek held together by one or two stitches, adhesive plaster and bandage. In no other way do I see that this formidable disease can be eradicated." (p. 58.) The operation which Lizars proposed, he endeavoured to perform in December, 1827, but without success, and he thus mentions it (a) :—" I attempted to remove this bone for a medullary sarcomatous tumour of the antrum, from a miner or collier, after securing the common carotid artery of the affected side, but I was prevented by the haemorrhagic disposition of the gum and palate, my patient having lost, in a few seconds, upwards of two pounds of blood, which welled out at every incision, as if there had been an aneurism by anastomosis. The man survived this attempt seven- teen months." (p. 54.) On August 1, 1829, Lizars performed his second operation (b) ; he first tied the trunk of the temporal and internal maxillary arteries, and also the external jugular vein which had been divided on the first incision. He cut through the alveolar pro- cess and bony palate on the left side of the palatine suture, and completely separated the upper jaw, with the saw, Liston's forceps and strong scissors; but the orbitar plate was separated from the eyeball by the handle of a knife. The tumour was medullary sarcomatous, and a portion of it, attached to the pterygoid process of the sphenoid bone, could not be detached; but part of the malar bone involved in the disease was removed. On the sixteenth day the wound had healed, and she left the house on that day. Three days after she expired suddenly, but no examination was permitted. Lizars' third operation (c) was performed on 10th January, 1830, on a woman, after having first tied the external carotid artery. After slitting up the nostril making a flap of the cheek, and divesting the borie of its coverings where it was to be sawn through, he applied the saw on " the front of the superior maxillary bone between the nostril and the mouth, or at the side of the mystaehial suture ; the pala- tine plate backwards from this, parallel with the longitudinal palatine suture, to near where the transverse palatine suture exists; across the same palatine plate towards the bulbous process ; upwards between the bulbous process and the pterygoid pro- cesses of the sphenoid bone, across where it joins the cheek-bone ; and, lastly, at its nasal process, parallel with the inferior margins of the lachrymal and nasal bones. I then-with strong seissors cut- the connexions of the orbitary plate with the os planum of the ethmoid bone, and orbitary process of the palate-bone, deep into the orbit, to the spheno-maxillary fissure, and was, lastly, able, by notching with the bone forceps at every point where the saw had been applied, to remove the entire bone which had its cavity filled with a firm sarcomatous tumour. The patient was able to walk about her room on the eighth day, and went out to take an airing on the thirtieth day; and she left the Hospital on 5th March following." (p. 55.) I have, for the sake of convenience, put these three cases together; but although Lizars first proposed the operation in this country, it was first performed by Gen- soul, of Lyons, on 26th May, 1827, who states that he was not aware what method Lizars had employed (d), on a lad of seventeen, for a fibro-cattilaginous. tumour of the upper jaw-bone, " occupying the whole left side of the face, and pushing to one side the orifice of the mouth ; it extended from above downwards, from the floor of the orbit to two lines above the chin; from before backwards, from the nose, which was thrust to the right, to the top of the" angle of the inferior maxillary bone." (p. 17.) He did not first tie the carotid ariery, but " made a vertical cut from the (a) Lancet. 1829-30 ; vol. ii, (b) London Medical Gazette,, vol. v. p. 92. (c) Lancet, above citei (d) Above cited. OF THE UPPER JAW. 757 inner corner of the eye vertically down through the upper lip,.opposite the left cus- pid tooth. From the middle of this cut, or rather nearly on a level with the floor of the nose, he made a second up to four lines from the front of the lobe of the ear, and a third cut beginning five or six lines to the outside of the orbit down to the end of the second, and then turned the flap up to the forehead. But for the purpose of completely exposing the tumour, he was obliged to continue, from the junction of the second and third cuts, another along the inner edge of the m. masseter to within an inch of the base of the lower jaw; and this lower flap he turned down. He then commenced with a chisel and malletcutting through the outer margin of the orbit near the suture connecting the malar and frontal bones, into the spheno- maxillary fissure : and next cut through the zygomatic process of the malar bone. The maxillary bone being thus freed externally, he placed a very broad chisel below the inner angle of the eye, and carried it through the lachrymal bone and the orbitar plate of the ethmoid ; and in the same way detached the corresponding part of the nasal bone. Cutting away with a bistoury all the soft parts connecting the wing of the nose to the upper jaw, he proceeded to separate the two superior maxillary bones, which he effected easily and quickly, having drawn the first left incisive tooth, by introducing a chisel not directly from before backwards, but by wriggling it through the mouth. Lastly to detach the maxillary bone from the pterygoid processes of the sphenoid, and to destroy any connexions with the back of the ethmoid still remaining, he thrust the chisel into the tumour, passing it ob- liquely in the orbit, so as to cut through the superior maxillary nerve, which he was anxious not to drag, and to push it sufficiently deep to form a lever, so as that he could turn the tumour down into the mouth. This answered very well, and he had then only*to divide with curved scissors and bistoury the attachments of the bone to the soft palate, so as to leave the latter unharmed. The operation was scarcely con- cluded, when the patient fainted, but revived on being laid upon his bed. The flaps of the wound yielded but a few. drops of blood and the bottom oozed but slightly. About an hour after, no ligatures being needed, the edges were brought together with pins and* twisted suture. On the eighth day the sutures were re- moved, and the wound was healed, except a very small portion of the middle cut." (p. 18-23.)] 2849. Cutting away the diseased jaw is now effected by means of Hey's saw, or the osteotome, in the different ways, according to the extent of the disease. If only a: portion of the upper jaw, with its broad base to- wards the alveolar process, have to be removed, two A shaped cuts united together, are to be made with the saw, including all the diseased part. If the swelling be broader above, a vertical cut must be made on each side, connected at the upper part with a transverse cut with the saw, or with the chisel and hammer. If the extent of the diseased bone be still greater, so that the whole jaw must be removed, the outer wall of the orbit must be divided with the chisel and hammer, near the suture connecting the cheek-bone with the outer orbitar process of the frontal bone, so that the chisel should penetrate into the spheno-maxillary fissure, and afterwards the zygomatic process of the cheek-bone is to be divided in like manner. The upper jaw-bone having been thus separated on the outside, a very broad chisel is placed below the inner corner of the eye, and held in such direction that when struck with the hammer, it passes through the lower part of the os unguis and the orbitar plate of the ethmoid bone. The ascending nasal process of the jaw-bone corresponding to the nose-bone, is to be separated in the same manner; and all the soft parts connecting the wing of the nose to the upper jaw are now to. be cut through. The incisive teeth of the affected side are now to be inclined outwards, and whilst the chisel is entered between the two upper maxillary bones, not directly from before backwards, but obliquely from the mouth, their se- paration is very quickly and easily effected. Lastly to separate the jaw- 755 OF RESECTION bone from the pterygoid process, and any still remaining connexions with the ethmoid bone behind, the chisel must be passed from the orbit obliquely downwards to loosen every thing which has firm adhesion, and by lever-like movements, to push down the separated bone into the mouth. Nothing more remains but to cut through the attachment of the palate- bone to the soft palate^ either with the curved scissors or with the bis- toury, in such way that the latter may still remain connected with the pterygoid process, and with its other side. When the upper jaw-bone has been removed, there is a large cavity bounded on the inside by the mucous membrane of the septum narium, above and before by the lower straight muscle.of the eye, by fat and' cellular tissue, the outside by the cellular tissue beneath the m. buccinator, and behind by that part of the throat above the soft palate. In five cases in which, I have performed resection of the upper jaw with perma- nent success, I", have operated in two cases according to the first; in one according to the second; and in two cases according to the third method; only that besides the chisel, I used Hey's saw for the division of the bones. In other two cases the disease returned. Heyfelder (a) performed resection of both jaws in the following way :—He made two cuts from, the outer angles of the eyes into the corners of the mouth, then sepa- rated all the soft parts from the swelling to the inner corners of the eyes and to the nose-bones. He then raised this four-cornered flap upon the forehead, carried Jef- fray's chain-saw through the upper fissure of the left orbit, and divided the connex- ion of the left upper jaw-bone, and cheek-bone. In like manner he proceeded with the division of this bone from its Connexion with the frontal, laehrymal, ethmoid, and nasal bones. In the same way, the right upper jaw-bone was separated from its connexions, and afterwards -the vomer and the still remaining connexions were cut through with strong scissors. A lever-like pressure was made on the upper part of the tumour to complete the operation. Torsion and compression stanched the bleed- ing, and twenty-six sutures united the wound. [Syme's, (b) directions for performing excision of the upper jaw-bone are the most simple, and will not be found less convenient than any other. He says " two inci- sions should be made through the cheek, one extending from, the inner angle of the eye directly downwards to the lip, the other beginning over the junction of the max- illary, and malar bones and terminating at the angle- of the mouth. The triangular flap thus formed is to be dissectedtfrom the tumour, and? the margin of the orbit ex- posed." (p. 487.) Liston (c) performs this operation in the following manner:—" The extent of the disease is to be accurately ascertained, and the points at; which the bones require to be separated decided upon. If the os malae he involved, and it is necessary to re- move it as well as. the superior maxilla,, a pair of straight tooth-forceps, a full- sized bistoury, copper spatulre, powerful scissors, artery forceps and needles for interrupted and twisted suture will be sufficient. If the superior maxilla only, with, perhaps, some of the smaller bones, is to be removed, then the addition to the apparatus of a small saw will be necessary for the purpose of more readily effecting the separation oftthe os malae from its anterior attachment. The proceeding is not to be dreaded on account of its extent; indeed, removal of the superior maxilla alone is the more troublesome. Supposing that the more extensive extirpation is required, incisions must be made so as to expose freely the tumour and bones where it is proposed to cut them*. First of all, one Of the central incisors must-be extracted, either the one on the affected side or the other, according to the extent of the tu- mour. I have been obliged to remove a considerable portion of the jaw opposite to that principally affected; and in that case one of the molares was removed, in order to admit ofthe division of the bones. The point of the bistoury is entered over the external angular process of the frontal bone, is carried down through the cheek to the comerjof the mouth, and is guided hy the fore and middle fingers of the one or (a) Chiruxjfische und Augenkrankea-KU- (6) Principles of Surgery.. Third fidi- nikum der- Universitat, Edsmgen, p. 81. tion.. 1844. (c) Practical Sargery.. OF THE UPPER JAW. 759 other hand, as may be placed in the cavity. A second incision made along and down to the zygoma falls into the other. Then the knife is pushed through the in- tegument to the nasal process of the maxilla, the cartilage of the alas is detached from the bone, and the lip is cut through in the mesial line. The flap thus formed is quickly dissected up, and held by an assistant; the attachment of the soft parts to the floor of the orbit, the inferior oblique muscle, the infra-orbital nerve, &c, are cut, and the contents of the cavity supported and protected by a narrow bent copper spa- tula." (pp. 311, 12.) Or, the flap may be formed in the following way with less extensive cuts. " The incisions were commenced at the inner canthus of the eye, carried by the side of and close to the ala of the nose, along the margin of the nostril, and then through, the upper lip exactly in the middle line. Another incision was made from the commencement of the first, in a curved form, along the lower margin of the orbit, and., of course, in the directions of the fibres of the orbicularis palpebra- rum. The flap thus formed was, by dissection, turned outwards and held by an as- sistant until the processes were cut." (p. 314.) Fergusson's (a) directions for making the skin-flap are, " that an incision should be made from the margin of the upper lip towards the nostril, and then from the ala, as high as within half an inch of the inner canthus of the eye-lids; next the cheek should be laid open from, the angle of the mouth (or near it) as far as the zygomatic process of the malar bone, and, if necessary, an incision at right angles with this one should extend from the external angular process of the frontal bone, towards the neck of the lower jaw; now the flap between the nose and the wound in the cheek should be dissected from off the tumour, and turned upwards on the brow ; then that portion of the cheek below and behind the wound should be turned downwards, and the mucous membrane divided, so as to expose freely the interior of the mouth." (p. 548.) Cases may certainly occur in which the use of chisel and hammer may be neces- sary, but they cause great jarring and should not be used by choice, more especially as in general the detachment of the jaw can be most quickly and conveniently made, cutting pliers, or nippers, and strong scissors, as recommended by Syme and Liston. The former directs, that " one blade of a large pair of cutting pliers be introduced into the nose, and the other into the orbit, so as to divide the nasal process of the maxillary bone. The connexion with the malar bone is next separated in the same way, and then the palate, previous to which one of the incisor teeth roust be extracted, if necessary. The surgeon having now deprived the bone of all its principal attach- ments, wrenches it out either with his hands or strong forceps." (p. 487.) Liston's proceeding is nearly the same. " With the cutting forceps the zygomatic arch, the junction of the os make and frontal bone by the transverse fecial suture, and the nasal process of the superior maxilla are cut in succession; then, a notch having been cut out of the alveolar process, the palatine arch is clipped through by strong scissors placed along it, one blade in the nostril of the affected side, the other in the mouth. Then it is that an assistant will be prepared to place his fingers on the trunk of one or both carotids. The tumour is now shaken from its bed, and, as it is turned down, the remaining attachments are divided by the knife ; the velumpalali is carefully pre- served, and also, if possible, the palatine plate of the palate bone." (p. 312.) O'Shaugnessy (b) has given in his short but clever book, the following account of the removal of the upper jaw of a Hindu, of twenty*-one years of age, which he performed in November, i837. " An enormous growth completely occupied the left side of the face, rising to a level with the floor of the orbit, and extending a long way below the inferior maxilla, but unattached to it; occupying the whole of the anterior and left side of the mouth, and protruding between the lips, pressing down the lower jaw, so as almost to make the chin touch the throat, and flattening the nose, so as to leave but little trace of the prominence of that organ. Still there was no difficulty of swallowing, and the patient seemed to breathe without inconvenience, through the right nares. That portion of the tumour which protruded through the mouth was of a bright red colour, and covered with mucous membrane, having at its upper part the canine, and two incisors of its own side, with the central incisor of the opposite maxilla sticking out of it. The dimensions of, this mass were as follows :—From (a) Practical Surgery. (Jo) On Diseases of the Jaws, with a brief Outline of their Surgical Anatomy, and a description of ihe Operations for their Ex- tirpation and Amputation, &c. Calcutta, 1844. 8vo. 760 OF RESECTION the part near the ear to the most prominent part which protruded from the mouth, ex- actly twelve inches, and from that part which bulged below the inferior maxilla to the edge of the orbit, about ten inches. It looked, as near as may be, equal in size to the patient's head. * * * The principal source of pain to the patient seemed to be, from distention and pressure on the surrounding parts." (pp. 70, 71.) Notwithstanding its large size, the tumour seems to have been removed without much difficulty, the zygoma having been first Cut through, and afterwards the malar bone info the spheno-maxillary fissure, with Liston's bone-nippers. The orbitar process of the superior maxillary bone and the nerve were next cut through with a strong knife, and afterwards the nasal process of the bone. The second incisive tooth on the opposite side having been drawn, the extent of the disease requiring it, the alveolar process and hard palate, as far back as the palatal process of the palate- bone, were then cut through with the bone-nippers," and now all the strong attach- ments of the tumour being completely severed, he had no difficulty in removing that mass, carefully separating with the knife the palatal process of the superior maxilla from the palatal process of the palate-bone, so as to preserve the soft palate from in- jury. The tumour weighed four pounds, it was nearly globular in form, having at its inferior surface a deep groove into which the lower jaw sunk, and the teeth be- fore mentioned projecting from its anterior upper part." (pp. 73, 74.) The patient did not lose more than eight or nine ounces of blood, no ligatures were required,and a few minutes after the tumour was removed, all bleeding ceased. "The mouth remained as wide apart after the operation as before the tumour that distended it was removed; he appeared to have lost the power over the muscles that raise the lower- jaw." (p. 78.) This, however, was gradually recovered, and on the eleventh day " the mouth was nearly as small as it ever could have been." (p. 79.) The patient completely recovered. Hetling (a) of Bristol, relates a case of Osteosarcoma; or rather, as he says, it should be more properly called, from its true character, medullary sarcoma of both jaws, in a woman of twenty-three, upon whom he operated, removing part of the upper jaw, and part of the lower jaw, which latter he exarticulated. "The tumour extended from the upper to the lower jaw, to the latter of which it adhered so firmly, as to render it completely immovable, so that the patient could not masticate, and could scarcely articulate, being only enabled to answer questions put to her, by in- distinctly mumbling 'yes,' or 'no.' In this state she was compelled to live upon fluids, and even these were with difficulty swallowed, deglutition being much im- peded by the pressure of the tumour upon the internal part of the mouth." (p. 279.) The operation consisted in making a crucial cut through the cheek from the mouth to the lobe of the ear, and from the infraorbitar edge to the angle of the jaw, turning Up the flaps and exposing the diseased mass, "the base of the tumour was found to occupy the palatine and maxillary portion of the upper jaw, and in its extensive growth, its head had been forced down and attached to the ridge of the lower jaw, nearly as far as the symphysis, extending along the whole of the alveolar border, nearly in a horizontal line from the mental foramen to the condyloid process, the whole of which portion was discovered to be either absorbed or m a state of caries, from the long-continued pressure of the tumour. In fact the tumour had so worked its way across the lower jaw, both inwards and outwards, that it was found buried in its substance, and, consequently, absorption of its body had been going on for some time on both sides of'the bone. The substance of the tumour was next sepa- rated by the knife and fingers, from its base and adhesions. When this was effected, an extensive irregular surface of bone was found in a state of'cartes, extending in the upper jaw from the pharynx across the palate to the malar bone. Not the least vestige of the thin walls of the antrum remained. Fortunately, the floor of the orbit was left uninjured. With the assistance of Liston's bone-cutter, small saws, &c, every portion of diseased bone was taken away that could be safely removed, and the general surface scraped as carefully as possible with the knife, it being intended, finally, to apply the actual cautery over the whole plane of the diseased bone. Having accomplished this tedious and difficult part of the operation, ample room was found for amputating the lower jaw at the articulation ; caries having extended as be- fore stated, from near the symphysis along the whole of the upper margin to the joint. (a) Transactions of the Provincial and Medical and Surgical Association, vol. i. London, 1833. 8vo. OF THE UPPER JAW. 761 This extensive line of bone was then sawed off, except the condyloid process, which was afterwards easily disarticulated and removed with Liston's bone-outter, having first divided the fore part of its capsule, and also the temporal muscle from the coro- noid process." (pp. 284, 85.) There was no bleeding of consequence, and the ac- tual cautery was not applied. The flaps were brought together with sutures ; on the fourth day the external wound had united, and in course of a fortnight, she walked about the ward. She left seven weeks after the operation, restored to a healthy ap- pearance. This operation did not ultimately succeed, for Heltling states, " that the disease returned some time after the patient left the Infirmary, that she languished for about a twelvemonth, and died." (p. 336.) This result is what usually happens in these cases of fungoid tumours of the jaw, if the whole of the bones affected, cannot be, or are not, removed by the operation. And Liston has justly observed :—" If any thing is to be done, it ought to be under- taken with a thorough determination to go beyond the limits of the morbid growth, to remove the cavity which holds it, and thus get quit, if possible, of all the tissues implicated, or which may have become disposed to assume a similar action. I know from experience, that this step, if adopted in time, may prove successful; and though at least a doubtful and very severe proceeding, not by any means unattended with danger, it is the only remedy. Let it be borne in mind, that it is only in the very earliest stage that any benefit can accrue even from the thorough extirpation; very generally the case is not presented until much too late, to one who understands the nature of the malady, who is capable of undertaking its treatment, and who has courage to propose and perform what is necessary. After the parietes have given way, and the growth has appeared in the nostril or cheek, the case is hopeless; and the patient, as, of old, were those who ventured on the ocean, may be numbered with the dead." (p. 307.)] 2850. After the wound has been properly cleansed, every spouting vessel must be tied or twisted, the parenchymatous bleeding stanched with cgld water, or with the actual cautery, the application of which may be necessary to destroy any remaining diseased part, the edges of the wound brought together and closed with the interrupted or with the twisted suture, and the interspace with strips of sticking plaster. Filling up the cavity with lint is injurious, but laying in some pieces of German tinder convenient, as when suppuration comes on, it easily and completely separates. 2851. The after-treatment must be conducted according to the general rule. The dangers to be dreaded are violent inflammation, which may extend down the throat and to the brain ; nervous symptoms; ill-conditioned copious suppuration, to contend with which frequent washing the mouth with warm water or any slightly aromatic infusion are most proper, at the same time supporting the strength; after-bleeding, for which com- pression with German tinder must be made, which I employed in two cases with success; necrosis of the cut surfaces, which require purifying washes for the mouth, and the ultimate removal of the separated pieces of bone ; fungous granulations, which may be touched with caustic or with the actual cautery. If the disease recur, it depends upon the previous extent of the resec- tion and the other conditions of the patient whether any repetition of the operation should be undertaken. Palsy of the face diminishes and gene- rally after a time ceases. Upon this subject may be consulted also, Chelius; in Heidelb. klinisch. Annalen. Guthrie; in London Medical Gazette, vol. xvii. p. 315. 1835. Blandin; in Gazette Medicale de Paris, vol. ii. p. 344. 1834. Adelmann, Untersuchungen iiber krankhafte Zustande der Oberkieferhohle. Dorpat, 1844. [ 762 ] II.—Of Resection of the Blade-bone. von Walther; in his Journal fur Chirurgie und Augenheilkunde, vol. v. p. 271... Haymann; in the same, p. 569. 2852i The practicability of this operation von Walther rested on his experiments upon the dead body. The blade-bone is laid bare by a crucial cut through the skin, forming flaps by turning it back, but leaving the muscles on the hinder surface of the bone; the insertions of the mus- cles are cut off close to the outer and inner edge of the bone, which is then sawn through transversely immediately below the spine, so that the upper angle and all the parts above the spine remain; lastly, the subsca- pular muscle is separated and the muscles generally on the front of the bone, which can be done with the handle of the knife. The trunk of the subscapular artery is not in this way injured. 2853. Haymann performed this operation successfully on account of a tumour attached to the blade-bone. He laid it bare with two large semi- lunar cuts through the skin and tendinous expansion, and cut it away with some quick strokes of the knife; the bone was then sawn obliquely through the spine, so that only the glenoid cavity and the parts above the spine remained. After the cure the upper arm could be moved in most directions, its elevation alone was interfered with. Liston (1), Janson (2), Luke (3), Syme (4), Wutzer, and Textor have per- formed this operation (5). [(1) Liston (a) removed in 1819 about three-fourths of the scapula, leaving only the glenoid cavity, processes, and half of its spine. It had been at first intended to remove " a very large, hard, inelastic tumour, firmly attached to the bone, and ex- tending from its spine over all the lower surface of the bone;" but on attempting to detach it from the spine, " the knife and fingers suddenly slipped into its substance. This was attended with a profuse gush of florid blood, with coagula." Liston then considered it necessary to remove the portion of bone above mentioned. The disease seemed to have been medullary sarcoma. The disease, however, recurred, and the patient died. - (2) Janson (b) removed a large portion of the blade-bone which was involved in a tumour, but left the glenoid cavity. (3) Luke's (c) operation in October, 1828, was for a medullary sarcomatous tumour, occupying the whole of the infraspinate pit of the blade-bone, and protruding from the subscapular-pit deeply into the arm-pit. The patient was a girl of fourteen, and had only noticed the swelling about six weeks. He " made an incision through the skin, beginning at the axilla, and expending it along the axillary margin of the tumour and anterior costa, and then with a sweep around the inferior angle to within a short distance of the spine of the scapula. He extended a second incision from the commencement to the termination of the first, along the lower margin of the spine; also through the skin, which being drawn upwards, exposed the spine and adjoining muscles. The muscles lying over the supra and infra spinal/ossa were next divided in the direction which he proposed to saw through the bone. * * * By grasping the tumour and inferior angle in his left hand, the scapula was steadied whilst he sawed it through in a direction from a little behind the glenoid cavity to a little above the superior angle, which latter was therefore removed, the spine being sawn through near to the root of the a.cromion.,, (p. 237.) The soft parts were then carefully separated from the tumour, which, was detached with about three-fourths of the scapula. The bleeding was free, particularly in the neighbourhood of the armpit, where the axillary vessels and nerves were exposed. Twenty or thirty arteries were tied, and about a pint or a pint and a half of blood was lost; but the girl did not faint. The edges of the wound were brought together with straps of sticking plaster, (a) Edinburgh Medical and SurgicalJour- (b) Malgaigne, Medecine Operatoire, p. nal, vol. xvi. p. 66 and p. 215.—Elements of 246. . Surgery, p. 190. Second Edition. (c) London Medical Gazette, vol. V. 1830. RESECTION OF THE COLLAR-BONE. 763 the arm secured with a bandage to the side and the fore-arm put in a sling. In about two months the wound had healed completely. Eleven months after the operation, " the motions of the arm forward and backward were perfect, and in fact more than ordinary, the limb moving with more than usual pliancy, but yet there was considerable power. She can also perform the actions of rotation outwards and inwards. The elevation of the arm from the side cannot be easily accomplished, and requires the aid of the opposite hand to raise it to a horizontal level. She possesses considerable power, and can lift with ease moderately heavy substances." (p. 239.) (4) The operation of Syme's (a) here alluded to, like Liston's, sprung out of another, which was amputation at the shoulder-joint for a fibro-cartilaginous tumour of the upper part of the humerus, having exposed which, he "easily cut through the acromion process and clavicle, and then depressing the arm, separated its remain- ing attachments. It now appeared that a fibrous anchylosis had existed between the glenoid cavity and the tumour, which had a cup-like form, and embraced it on all sides. He therefore sawed through the neck of the scapula, and removed a portion of the bone, including the coracoid process." (5) Travers in July, 1838, removed all the blade-bone immediately below its spine, for a large medullary sarcomatous tumour occupying the whole infraspinate pit. He first cut through the skin from the upper to the lower angle, and next from the root of the acromion, along the inferior costa to the beginning of the first cut. He then turned up the flap of skin to rather above the spine of the bone; detached the rhomboid muscles from its base and the m. teretes and latissimus dorsi from the in- ferior costa and angle, and next made a cut immediately beneath the whole length of the spine down to the bone, in doing which a large gush of bloody fluid, as in Liston's case, followed. The base of the bone first, and afterwards the inferior costa, were sawnthrough with a narrow saw ; and it was then attempted to cut across the bone with cutting nippers, but this failing it was sawn through without difficulty, close to the spine. The bleeding was severe, and he was much exhausted, but only seven vessels were tied. The flap was laid down and fixed with two sutures and straps of sticking plaster. The wound healed kindly in about three weeks ; but three months after the operation, a small tumour of the same kind appeared in the scar, and soon after another on the side of the chest. These gradually increased, burst, and threw out bleeding fungous growths ; but he lingered a long while, and died just twelve months after the operation. III.—Of Resection of the Collar-bone. 2854. Resection of the collar-bone, which may be indicated in commi- nuted fracture, if the sharp ends of the fracture thrust outwards or injury to the vessels or nerves be feared, in caries and necrosis, and bony tumours, requires, according to the different states of the soft parts, a transverse cut along the bone, from the two ends of which a small vertical cut must be made, or two elliptical cuts, including the diseased part; or for a very large swelling a crucial cut. The bone is then carefully separated from the soft parts, the knife being always kept close to it; a spatula or a leather strap is thrust beneath the bone, which is then cut through with Hey's saw or with the osteotome. The edges of the wound are brought together with sticking plaster, lint and compresses put over it, and the arm supported with Desault's or Boyer's fractured clavicle apparatus. In the total removal of the collar-bone, which Cuming (b) performed after ampu- tation at the shoulder-joint, and removal of the blade-bone in consequence of a crush by a gunshot-wound, Meyer (c) and Roux (d), on account of caries, Warren (e) (a) Edinburgh Medical and Surgical Jour- nal, vol. xix. p. 17. nal, vol. xlvi. p. 249. 1836. (d) Bulletin general de Therap., vol. vi. (6) London Medical Gazette, vol. v. p. 273. livr. 8. 1830. (e) American Journal of Medical Science, (c) von Graefe und von Walther's Jour- vol. xiii. p. 17. 1833. 764 RESECTION OF THE BLADE-BONE AND COLLAR-BONE. and Mott (a) for osteosarcoma, a cut was made along the collar-bone, and brought down a little below each end, at which a vertical cut about two inches long was made, the flaps turned back and the bone laid bare. The acromial end was then dis- jointed, the bone raised up and separated by disjointing its sternal end. [Travers (b) operated on a boy of ten years old, who, in consequence of a fall which probably broke the collar-bone without rupturing the periosteum, had large effusions of blood within it, which formed a tumour that by degrees involved and destroyed nearly the whole bone, except at its sternal end. He made " a crucial incision through the integument and platysma myoides, one limb of which was nearly in the line of the clavicle, and the other at right angles; and the flaps and fascial coverings successively dissected down to the external basis of the tumour. The pectoralis and deltoid muscles were then carefully detached from their clavicular origin, avoiding the cephalic vein, and the fibres of the trapezius and cleido-mastoid muscles divided on a director. One considerable vessel, in the situation of the transversalis humeri, required a* prompt ligature. The circumference of the tumour was now well defined, though it was found to be firmly imbedded and adherent on its posterior aspect. . Disarticulation of the scapular extremity of the bone was next effected without difficulty, and the mobility thus communicated to the mass facili- tated the completion of the operation. A director was now worked beneath the bone, as near to the sternal articulation as was practicable, and with a pair of strong bone- nippers thus introduced, it was completely and clearly divided. The subclavius muscle and a part of the rhomboid ligament were now detached from the tumour, and the mass being well raised by an assistant, while the edges of ihe wound were kept wide apart by metallic retractors, the cervical prolongations of the tumour were separated from their remaining connexions by a few touches of the scalpel without injury to the subclavian vessels, (pp. 137, 38.) A twelvemonth after, the boy had the full and free use of the arm." (p. 147.)] Mott gives the following account of his removal of the collar-bone :—" The inci- sion extended from the articulation at the sternum to the top of the shoulder, in a semicircular direction; below, the dissection, to get under the tumour, was on a line with the fourth rib; above, in a direction to the top of the shoulder, an inch below the thyroid cartilage and base of the jaw, and terminated at the same point with the first. The tumour of a bony character, was in contact with the coracoid process, insomuch that I was obliged to saw it through near the acromion scapulas. Below, the vein was imbedded in the tumour, from the coracoid process to the scalenus anticus. Then my attention was directed to separating the tumour from the deep- seated fascia of the neck, to protect the deep-seated jugular and thoracic dfcct, the operation being on the left shoulder." " This operation far surpassed in tediousness, difficulty, and danger, any thing which I have ever witnessed or performed. It is impossible for any description which we are capable of giving, to convey an accurate idea of its formidable nature. The attachment of the morbid mass to the important structures of the neck and shoulder of the left side,is sufficient to indicate its magni- tude and difficulty." So arduous was the task of separating the diseased clavicle from the vessels and thoracic duct, that he was at one time, he said, almost inclined to doubt the possibility of accomplishing his purpose (c). The operation lasted four hours, and thirty vessels were tied. The tumour, when separated, was the size of two fists. Chaumet (d) of Bordeaux removed four-fifths of the clavicle, on account of a tumour originating from it.] [IV.—Resection of Blade-bone and Collar-bone together. This formidable operation was successfully undertaken by Mussiey, of Cincinnati, who has published an interesting account of it (e). In 1818 a patient consulted him about a tumour connected with the thumb, for which the first metacarpal bone was removed. Several years later, pain (fl) American Journal of the Medical ences, vol. ii. p. 482. 1828. Sciences, vol. iii. p. 100. 1828. (d) Gaz. Med. de Paris, vol. i. p.209. 1846. (6) Med-Chir. Trans., vol. xxi. 1838. (e) American Journal of the Medical Sci- (c) American Journal of the Medical Sci. ences, vol. xxi. p. 390, 1837. RESECTION OF THE BLADE-BONE AND COLLAR-BONE. 765 attacked the humerus, which became greatly enlarged, and in 1831 the arm was amputated at the shoulder-joint. In 1836 the same disease appeared in the shoulder, and accordingly Mussey undertook the com- plete removal of the scapula and clavicle in September, 1837. " The tumour was round and prominent, measuring horizontally over the sum- mit, from the anterior to the posterior margin of its base, 14 inches, and vertically, from the upper to the lower margin of its base, 10 inches." The integuments were dissected away from the clavicle, that bone dis- jointed fronvthe sternum, its sternal extremity elevated and detached from the subclavius muscle, so as to admit of the finger of an assistant being passed under it to secure the subclavian artery. The subsequent steps of the operation consisted in " plain, coarse, and sometimes rapid dissec- tion." Having tied'the subclavian artery, Mussey divided the accom- panying vein, when a bubble of air passed into the latter, which caused the patient instantly to swoon, and he was roused with much difficulty from this state of collapse. "The immense wound, with flaps of seven or eight inches in extent, united by adhesion, and became consolidated and sound, literally without the formation of a teaspbonful of pus. In less than three weeks the patient was dismissed, and he rode home in a stage-coach between thirty and forty miles, and remained sound arid well in November. In 1841-, Rigaud (a) of Strasburg, amputated a man's arm at the shoulder-joint, for disease of the humerus. The man recovered, and remained well for eight months. A tumour was then found growing from the scapula, and Rigaud removed the whole of this bone, together with the outer extremity of the clavicle, in 1842. In two months the parts were healed, and the man remained well in July, 1844. M'Clellan, of Philadelphia, removed the scapula and clavicle from a boy. The patient recovered after the operation, but died from a return of the malignant disease in another part. Dr. Blackman, of New York, informs me, that Gilbert, of Philadelphia, has re- cently removed the scapula and clavicle, but I have not been able to ascertain the particulars of the operation. I am specially obliged to my friend Fergusson for the following short account of the removal of the whole scapula and part of the clavicle, which he has this day (Fe- bruary 6, 1847) performed on a man aged thirty-three, who had his right arm am- putated about three years ago for caries of the shoulder-joint. The humerus was ex- tensively diseased, which is presumed to have been the reason for amputating; and the glenoid cavity being also affected, was removed at the same time, but either not sufficiently, or else there had been subsequent extension of the disease. Ten or twelve fistulous openings communicated from the surface with the carious bone, which seemed to be so extensively diseased that Fergusson considered it best to re- move the whole bone. An incision Was made, beginning an inch and a half from the sternal end of the clavicle, along that bone to the acromion; room wa^s thus made to apply a saw to the middle of the bone. An incision Was next made in the course of the spine of the scapula, nearly to the base. The first cut was then extended down into the axilla. The posterior flaps were now partially dissected off the thick- ened mass covering the scapula; the anterior next raised, then them, pectoralis minor, next the m. trapezius were cut through, and the bone, being forcibly pulled out- wards, was soon severed by the division of the other muscles and tissues. The an- terior attachment of the trapezius had been in part divided when making way for the saw on the clavicle. The axillary vessel was not obliterated, but spirted freely when the finger was taken off the subclavian on the first rib, where it had been com- pressed ; during the operation not more than four ounces of blood were lost. There was no shock and no pain, for the patient Was under the iuflnence of ether during (a) American Journal of the Medical Sciences. 1844^; p. 512. I have not been able to consult the original import. Vol hi.—65 766 RESECTION OF THE RIBS. the whole time. He was not aware that the operation was actually done, though he fancied it was going on. ,, , , 3, ■, Gaetani Bey (d), in the case of a boy fourteen years old, who had been severely wounded in the shoulder by the discharge of an old piece of artillery, which ex- ploded whilst re-melting, amputated at the shoulder joint, removed the whole blade- bone, which had been broken into several pieces, and cutoff the acromial end of the collar-bone. In about two months the wounds were healed. It may not be amiss to notice here five cases, in which the arm and the entire scapula'were torn from the body by machinery. In the first case, related by Bel- chier (b), no arteries were 4ied, and the man was well in two months. James (c) records a similar accident to a boy eleven-years old, and here again no ligatures ap- pears to have been required, and the cure was complete in nine weeks. Scar- nell (d), removed the outer third of the clavicle which projected from the wound, and tied the subclavian artery. In a patient of Lizars's (e), the outer half of the clavicle was torn away, as well as the arm and scapula; a ligature was placed on the subclavian artery, which had bled but -little, and the patient rapidly recovered. A similar case did equally well under the care of Cartwright (/). V.—Of Resection of the Ribs. 2855. Resection of the ribs, which has often been performed for in- curable disease restricted to the bone, as in caries and bony tumours, (Percy, Cittadini, Richerand, Milton, (g) Antony, {g)MorT, Clot- Bey, Jaeger, Textor,) requires the rib to be laid bare by a longitu- dinal or transverse cut; the intercostal muscles are then divided by a cut, first at their upper and afterwards at their low«r edge close to the bone, and the intercostal artery tied if it bleed. The pleura is then separated with a blunt needle and the rib cut off with an osteotome, which, in con- sequence of its sheath, best ensures the pleura from wound. The wound is to be lightly filled with lint or German tinder, and treated in the usual way. In compound comminuted fractures of the ribs, the removal of the ends of the bone with the saw may be necessary; though here the greatest caution is always requisite to avoid injuring the pleura, which is closely connected with the rib, whilst in caries the pleura is generally thickened, and in part also separated from the rib. In a case where about an inch-and-a-half of theninth rib had been removed, Tex- tor found a mass of new bone at the .place where the removal had been made, al- though caries had extended backwards to a considerable extent, the whole of the diseased part not having been completely removed. [Warren (h) removed, in January, 1836, a large, hard, immovable tumour, with a fistulous opening, and situated on the junction of the sixth and seventh ribs with their cartilages, which had existed about four years. He made an oblique cut over the swelling, and at each erid of it another at right angles, so as to form two quad- rilateral flaps, which being turned back, a firm cartilaginous substance was exposed, that had destroyed the natural appearance of the parts. This was removed, partly hy shaving off' with the scalpel, partly by bits with the cutting forceps, and both ribs were then found carious. These were carefully detached by a probe from die pleura, which was much thickened, and from the diaphragm, and three inches of (a) Annali Universali di Medicina, vol. (/) Fergusson, p. 235. xcviii. p. 5. 1841.—^London Medical Ga- (g) [These names evidently refer to the zette, vol. xxxi p 286. 1842. same operation, viz. that of rest ction of parts (6) Philosophical Transactions, vol. xl. of the fifth and sixth ribs by Milton Antony, 1741. M.D. of Georgia. See Philadelphia Journal (c) London Medical Gazette, vol. v. p. 497. of the Med. and Phys. Sciences vol. vL 1830. 1823,-g. w. n.] (d) Lancet. 1832 ; p. 114. (h) Boston Medical and Surgical Journal. '■■&) Fergusson's Practical Surgery, p. 235. 1837.—Lancet. 1837-38; vol. ii. p. 606. RESECTION OF THE FIBULA 767 the seventh rib with its cartilages, with two inches of the sixth, were removed by the chain saw and cutting forceps. There was little bleeding, the intercostal arte- ries having been obliterated in the course of the disease. He recovered. War- ben also removed in March, 1837, an osteosarcomatous tumour; circular, above six inches in diameter and three in height, covering parts of the seventh, eighth, ninth, and tenth ribs, attached to all, but most firmly to the ninth. It had been growing. six years. A "J" cut was made through the skin, and the flaps having been turned back, the insertions of the external oblique muscle were exposed and dissected off, as was also the m. latissimus dorsi, which latter was divided with some difficulty, and excessive pain. The tumour then found originating from the ninth, but firmly connected with the seventh, eighth, and tenth ribs, was then cut off from the former about an inch distant from its junction with its cartilage. The intercostals were then cut through, the diaphragm carefully separated from the rib and pleura, a- di- rector passed under the points where the rib was to be divided; and this done with cutting forceps, removing about two inches of the bone, and a part of its cartilage ; upon which the diaphragm immediately rose up like-a hernia. There was little bleeding, and no vessel required tying. This case did well. Dixon (a) removed the cartilage of the tenth-rib of the left side, which had been broken off two years previously, and from a few weeks after had caused severe neu- ralgia at first in the part and then over the region of the stomach, and had become al- most unbearable. A careful dissection exposed tha cartilage unattached ; it was easily removed; the pain immediately ceased, and the patient completely recovered in the course of a week. In a case of necrosis of the fifth rib, of which Roux (b) removed with the chain naw, four inches, a collection of matter was found between it and the pleura, not, however, communicating with the cavity of the chest. Within a few days, respira- tion became oppressed. He was attacked with symptoms of pleuritis on the right side, and died. On examination, the right cavity of the chest was found to con- tain a considerable quantity of purulent serum, with albuminous flakes of recent formation. The lungs were filled with softened tubercles, as might be expected; the patient having been much emaciated, and coughed much with copious expecto- ration, previous to the operation.] V.—Resection of the Fibula. [2855.* Resection, or Extraction of the Fibula, was proposed by De- sault, but has been, however, only recently performed by Setjtin (c). He detached the muscles from the bone, then applied the crown of a trephine below its head, slipped a narrow riband between the bone and the muscles on its inner side, down to the outer malleolus, and cut it off with a curved saw. Malgaigne removed the upper third of the^z&i^^ and exarticulated it; but care was necessary to avoid injuring the ante* rior tibial nerve as it passed round the neck of the bone.] 2856'. From this account of the several resections in the contiguity and continuity of the bones, it may be easily determined which mode of prac- tice shall be pursued in the partial resection of some bones, to wit, the radius, ulna, tibia,fibula, metacarpus and metatarsus, and so on; as also in the entire extirpation of single bones. For a careful collection of the cases hereto belonging, see Jaeger, Handworterbuch der Chirurgie, Article Resectio ossium, vol. v. (a) New York Quarterly Journal, No. I.—Lancet. 1839-40 ; p. 137. (b) Journal Hebdomadaire, vol. vii. p. 299. (c) Malgaigne, Medecine Operatoir* p —Lancet. 1829-30; vol. ii. p. 619. 249. Fourth Edition. 1843. 768 POSTSCRIPT. Kreitmair, Darstellungdes Ergebnisses der im konigl. Julius Spitale zu Wurz- burg seit 1821 angestellten Resectionen. Wurzb., 1839. Schirlinger, Beitrag zur Casuistik der Resectionen. Wiirzb., 1841. [Resection of the Os Coccygis, for the cure of Neuralgia, has been done by Dr. Nott of Mobile. See New Orleans Medical Journal for May, 1844.—g. w. n.] Postscript. [The year 1846 seems in a fair way to be known as the Annus Mirabilis of Surgery. The profession and the public in both hemispheres are in a complete ferment, con- sequent on the discovery by Morton, an American dentist, of a mode of producing insensibility, during which an operation may be borne without pain, nay, even ren- dered so agreeable as to induce a desire for its repetition. This safeguard against pain, consists in inhaling the vapour of ether, till the person is brought by it into the condition vulgarly known as "dead drunk," in which state the operation is to be performed. From the accOunt given by Bigelow {a), it appears that this proceeding was'first largely,employed to render toothfdrawing easy, and in consequence of the success. which attended it, Warren of Boston, thought it might be useful in more serious surgical operations. He, therefore, on the 16th October, 1546, having put a patient under the ethereal influence, made "an incision near the lower,jaw of some inches in extent. During the operation the patient muttered, as in semi-conscious state, and afterwards stated that the pain was considerable, though mitigated; in his own words, as though the skin had been scratched with a hoe. There was, probably, in this instance, some defect in the process of inhalation, for on the following day the vapour was administered to another patient with complete success. A fatty tu- mour of, considerable size, was removed by Dr. Hayward, from the arm of a wo- man, near the deltoid muscle. The operation lasted four or five minutes, during which time the patient betrayed occasional marks of uneasiness, but upon subse- quently regaining her consciousness, professed not only to have been insensible to surrounding objects, to have known nothing of the operation, being only uneasy about a child left at home." (p. 271.) Two other cases are ajso mentioned by Bigelow, one of amputation above the knea, the other of removal of a portion of the lower jaw, during both which operations tire patients were insensible to pain. An account of this wonderful discovery reached this country on the 17th December, 1846, and on the 19lh, a young female, having been intoxicated by inhaling ether for a minute and a half, had a molar toOlh extracted from the lower jaw by Rorinson (b). On the same day, Liston (c) amputated the leg of one patient, and twisted off the great toe-nail of another, whilst they were under the influence of ethereal [inhalation, and " neitheriof the patients knew, when they recovered from their stupor, that the operation had been performed." (p. 251.) Since this time, the public and medical journals have been teeming with "pain- less operations " of all kinds, performed in all parts of the country. That insensibility to pain, consequent on complete intoxication by breathing the fumes of ether, may be produced in many cases, is beyond all doubt; but that this condition will be induced in all instances is certainly untrue. Its failure does not depend, as is asserted, on the inhalation not being properly performed, for all per- sons are not alike affected by it, however carefully and perseveringly the ether may be administered. In proof of this, I may select, from among many instances, a case which occurred during the present month, (February, 1847,) at St. Thomas's Hospital. A man, whose toe-nail was to be twisted off, inhaled ether most assidu- ously for more than half an hour, without the slightest degree of insensibility being induced ; but it could not be objected that he was not fully subjected to the influence of the medicine, since after twenty-four hours his breath was still so impregnated (a) Insensibility during Surgical Opera- Medical and Surgical Journal; cited in Me- tions produced by Inhalation ; from Boston dical Times, vol^xv. 1847. (6) Medical Times, vpl. xv, p. 273. (C) Ibid. POSTSCRIPT. 769 with the ether, that it was strongly smelt by persons standing at the foot of his bed. The avidity with which ethereal inhalation has been generally ad opted; and appa- rently without consideration of the possibility of its indiscriminate employment being ever attended with, danger, is one of the most remarkable circumstances con- nected with it. But, that it is not unfrequently accompanied with inconvenientand even dangerous results there can be no doubt. Bigelow, in his paper before the Boston Society, mentions the more or less severe cough, which was immediately induced in several of the cases he ■ relates. In another instance, I have known hasmoptysis and bronchitis induced,' in a patient who had previously- suffered from haemoptysis. Morris (a) states of'a. woman, that "she did not appear at all timid, andbegan to inhale the vapour with' the greatest confidence; after five or six inspi- rations she suddenly became deadly pale, and stated that she; was suffocating, and refused to continue breathing the ether; she had scarcely done speaking before she coughed violently three or four times,, the flbwyof. blood to. the head was instan- taneous : she became quite purple in the face, the temporal veins were much dis- tended; and the arteries throbbed violently; she was perfectly sensible, and com- plained of a sense of suffocation, and that she should die. She remained in this state for five minutes at least, when the face began to assume its natural colour. She was a long time before she was able to leave the house ; and after she had been at home-two hours had a fit; in which she was stiff and insensible for ten minutes. Although upwards of a fortnight has elapsed since she inhaled the vapour, she is far from recovered, complaining of a great deal of pain and confusion about the head, and oppression at the chest." He mentions also, of one boy, that " after having in- haled for a short time, instead of depressing him-, he became furious, called out loudly, and we had great difficulty in pacifying him ;" and of another, that the in- halation "brought on a most distressing cough, which continued so long as he breathed the vapour; after a time it produced precisely the same effect as nitrous oxide;,he laughed most heartily, and) looked quite idiotic. After waiting an hour he again tried the vapour, but with the same results." (p. 352.) Cotton also states, that in OnWof his cases " boisterous,, hysterical-like spasms followed, as-observed by Professor Barker, requiring all trio force of the bystanders to hold the patient. Further inhalation, however, served to effect the required degree of un- consciousness." (p. 35*3.) It has also happened,: that the patient has not recovered so speedily after the re- moval of the inhaler, as is commonly stated ; indeed, it was almost feared he was dead, and he only revived by pouring quantities of wine down his throat. In this case, .the surgeon who operated-noticed, that all vital resistance of the tissues had ceased* and that the sensation igiven by his knife was as if he were cutting into a dead body. I have thought it right to mention these facts, to put practitioners on their guard in the employment of ethereal inhalation, for I feel assured, that unless more cau- tiously employed than hitherto, it will not be long before many disastrous conse- quences will result. A medical friend of high standing, with whom I had some con- versation, insisted on the propriety of subjecting the patient to some preliminary trials of the effect of the inhalation before employing it at the time of operating. With this opinion I fully concur, and I should certainly adopt it, if I made up my mind to try inhalation at all; but upon that point I arn not decided, for I have con- siderable doubt of the propriety of putting a patient into so unnatural a condition as results from inhaling ether, which seems scarcely different from severe intoxication, a state in which no surgeon would be desirous of having a patient who was about to be submitted to a serious operation. It was Suggested, with much appearance of probability, that a far more important benefit than even the prevention of pain would arise from the use of ether; that it must lessen the shock to the nervous system generally, and that the after-treatment would be greatly facilitated by the absence of constitutional irritation But expe- rience has not confirmed these hopes. A patient who recently underwent an im- portant operation, which was performed with rapidity and skill while he was quite unconscious, gradually sank, and died in three weeks, although little blood had been lost, and there was no organic disease found after death to account for the un- (a) Medical Times, vol. xv. p. 273. 65* 77f> POSTSCRIPT. favourable termination of the case ; there were two fresh effusions-of blood beneath the arachnoid membrane. Another case, still more recent, .terminated fatally within three days ; the patient never rallied from the sedative effects of the ether, while, at the same time, the spasms in the stump of the amputated limb were unusually severe. In conclusion I may^observe, that there are no operations in whieh the use of ether seems to be so decidedly contra-indicated, as in those for the cure of Cataract; for, when.skilfully performed, they cause hardly any pain, so that stupefying the patient is at least superfluous. But voluntarily to induce congestion in an organ, where inflammation, once set up, is so difficult to control, and where if unchecked, it pro- duces such deplorable effects, appears to be the height of imprudence. Yet all this risk has been run, and the npn-professional public have been astonished to hear how quickly a Cataract may be got out: the final results.of the operations, have not been so eagerly proclaimed.—j. v. s.] [Warren,.I, Mason On the Inhalation,of Ether. Boston,1847. 8vo. G. W. N.] % ANALYTICAL INDEX- Abdomen, Wounds of, i. 501 ; varieties of wounds of the abdomen, i. 501; super- ficial wounds, i. 501; bruises—symptoms, treatment, and consequences, i. 501; treatment of wounds of the epigastric, internal mammary, or abdominal ar- tery, i. 502; Travers on the effects of injury of the abdomen, i. 502; general treatment of wounds of the abdomen, i. 502; penetrating wounds, i. 502; symp- toms, i. 502; Hennen on the escape of the intestines from injury, in penetrating wounds of the abdomen, i. 502; Green's case .of fatal penetrating, wound of the abdomen, i. 502; treatment of simple wounds of the abdomen, i. 503; Travers on wounds of the abdomen, i. 503 ; use of sutures in wounds of the abdominal parie- tes, i. 503; occasional symptoms caused by the use of sutures, i. 503; mode of applying the sutures, i. 503; Graefe on the application of sutures, and including the peritoneum in the suture, i. 504; treatment of penetrating wounds, i. 504 ; Hennen on the treatment of penetrating wounds of the abdomen, i. 505; protru- sion of the omentum or intestines, i. 505; return of the protruded part, i. 505; enlargement of the wound some- times necessary to effect the return, i. 505; condition of the protruded intes- tine a guide to its return, i. 506; if the omentum be inflamed, bruised, and partly disorganized, or gangrenous, it must not be returned, i.506; Dupuytren objects to the return of the protruded omentum into the abdomen, i. 507; Tfrounds of the Intestines, i. 507; symp- toms, i. 507; Travers", Green, Tyrrell, and South's cases of wounded intestines, i. 507; Travers on wounds of the intestines communicating directly with the surface, i. 508; varieties of wounds of the intes- tines,!. 508;. Travers on the varieties of wounds of the intestines, i. 508; difference of opinion as to the treatment of wounded' and protruded intestine, i. 509; different kinds of stitches employed, i. 509; Scarpa and Larrey's practice, i. 509; Denans, Beclard, Jobert, Lembert, and Reybard's . practice in wounded intestine, i. 509, 510; Shipton's and Travers' experi- ment, i. 511; Else, Benjamin Bell, John Bell, and Hennen, on the use of the suture in wounded intestine, i. 511, 512 ; objections to the use of stitches in wounded intestine, i. 513; reasons in favour of their use, i. 513; Travers on the objections to returning a wounded in- testine, without suture, into the abdomen, i. 514 ; Travers and Benjamin Bell, on the withdrawal of the suture, after union has taken place, i. 514; Travers' direc- tions for stitching a wounded intestine, i. 514; approval of Lembert's plan, L 515; Astley Cooper's practice in small wounds of the intestines, i. 515 ; Dupuy* - tren's modification of Lembert's plan, i. 515; Travers on the reparation by arr tificial connexion of the divided parts of a wounded intestine, i. 516; treatment of a perfectly divided intestine, oneend only being found, i. 516 ^treatment of wounded intestine, i. 516 ; treatment of wounded intestine when the faeces-escape by the wound, i. 516; Travers and South on the treatment of wounded intestine with- out fascular discharge or prolapse, i. 517; Travers on spontaneous - reparation in wounded intestine, i. 517; contraction of the intestine sometimes the result of a wound, i. 517; effusion of. faecal matter, blood, or other fluid constitutes the most dangerous complication of pene- trating wounds of the abdomen, i. 517; Travers and Hennen on effusions, into the cavity of the abdomen under such circumstances, i. 518; extravasation of the intestinal contents, i. 518; Travers on the impediments to effusion of the intestinal contents, i. 518; symptoms of effusion, i. 518; effusion of blood into the cavity of the abdomen, i. 519; the ef- fused blood is either collected in a cir- cumscribed space, or diffused over the abdomen, i. 519; treatment of extravasa- tion, i. 520; Hennen's case of musket- shot wound of the abdomen, the ball passing afterwards per anum, i. 520. .bernethy, on severe phlebitis, i. 93; 772 ANALYTICAL INDEX. on poultices, i. 101; on opening a cold abscess with a lancet puneturey orf a trocar, i. 105; onincisions in carbuncle, i. 157; on permanent chordee, from the extension of the inflammation to the corpus spongiosum, i. 178 ; on gonorrhoea virulenta, i. 183; objection toany attempt to check gonorrhoea, i. 191; recommends a soothing practice, i. 191; on lumbar abscess generally connected with carious vertebrae, i. 209; experiments to cause the absorption of the pus, i. 211; treat- ment of lumbar abscess; i; 212; supported by Astley Cooper and Lawrence, i. 213; on the symptoms of the inflammation which sometimes supervenes after the arb- scess has been opened, i. 214; paronychia ungualis, i. 215 ; paronychia tendinosa, i. 216; paronychia osseosa, i. 217; on epiny- chia, or ulceration, with great thickening at the ends of the fingers, i. 217 ; on the cure of epinychia, i. 221; case of wounded meningeal artery, i; 333; on a costive state of the system preceding tetanus^ i. 416; on the treatment of simple fracture of the skull with depression, without the tre- phine, i. 432; on puncturing the dura mater, to evacuate the effused blood i. 448; only employs the trepan in injuries of the head, when secondary symptoms of irrita- tion and pressure require it, i. 454; on the use of a broad-chest bandage in emphy- sema,!. 497; mode of treatment of wound- ed joints, i. 538; commended by South, i. 538; on the qtiestion of immediate am- putation in compound fractures, i. 568 ; on symptomatic fever; i. 571; the bracket splint, i. 574 ; denies the possi- bility of simple dislocation of the spine, i. 586; on the operation of trepanning the spine, i. 593; on pseudo-syphilis, ii. 81; on the means of distinguishing between true and'false syphylis, ii. 8L; on the oc- casional spontaneous healing of chancre, ii. 85; on the effects-produced by the ligature on the arterial coats,f i. 293; on the application of two ligatures, and the division of the artery between them, ii. 407; case of ligature of the internal carotid, on account of a wound, ii. 508 ; case of ligature of the external iliac in the groin, ii. 535 ; on the ligature of the external iliac, ii. 538 ; on compression in the treatment of teleangiectasy* ii. 561; on passing the bougie in stricture of the urethra, iii. -71; on the use of metallic bougies, iii. 71; on hemorrhage from the urethra after passing the bougie, iii. 77; on puncturing spina bifida iii. 189; on the division of tumours, iii. 381 ; on fungus haematodes, iii. 460; on the treatment of traumatic phlebitis, iii. 611; on the com- plete section of the nervous twig in cases, of wound of a nerve-branch in bleeding, iii. 611; case, of division of a nerve wounded in blood-detting; iii. 635; case of excision of part of the digital nerve, iii. 636; mode of amputating at the hip-joint, by the circular cut, iii. 689. Abscesb, i. 47,' 48 ; formation of the walls of, and the circumscription of the pus, i. 48 ; the walls are secreting and absorbing surfaces, i. 48; metastatic abscesses, i. 48; Travers on the lining membrane of an abscess, i. 49 ; Hunter and Trarvers on the circumstances which determine an abscess to the surface, i. 49; cold or lymph ab- scess i. 57; abscess of congestion, i. 57; symptoms of cold abscess, i. 57 ; Mr. South's case of cold abscess, i. 61 ; Dr. Rigby on puerperal abscess, following contagious or adynamic puerperal fever, i. 60; when an abscess is ripe, it either opens of-itself, or it must be opened, i. 102; small abscesses j ust beneath the skin, and those in glandular structures should alone be allowed toburst, i. 102; circumstances under which.the early opening of ab- scesses is required, i. 103"; circumstances under which abscesses are.opened Jate, i. 103; South recommends the early opening of abscesses just beneath the skin, and in glandular structures, i. 103; opening of ab- scesses (oncotomia) effected by the knife, escharotics, and the seton, i. 103; deep ab- scesses with thick coverings should be opened with the bistoury, i. 103 ; South's condemnation of pressure and squeezing an abscess^ i. 104; mode in which es- charotics are employed, i. 104; passing a-seton through an abscess, i. 104; open- ing an abscess with a cutting instru- ment generally preferable,!. 104; South on opening an abscess, i. 105; treat- ment of cold abscess, i. 105; various plans for opening a cold abscess recommended by Abernethy, Beinl, Walther, Schaack, Rust, Nasse, Zang, and Callisen, i. 105 ; in selecting his plan of operating, the surgeon must be guided by the difference of constitution, by the more or less weak state of the cellular walls, and by the size of the swelling, i. 105; constitutional treat- ment also required, i. 105; Kluge's plan of treating lymph abscesses, i. 106; fur- ther treatment after opening the abscess, i. 107 ; if there be deficiency of power in the part, stimulants may be used, but moist warm poultices are more effectual, i. 107; tonics may be given internally, i. 107; if the opening close too soon, the edges may be drawn asunder, or separated with a probe, i. 107 ; proud flesh repressed with caustic, i. 107; formation of fistulouspas- ANALYTICAL INDEX. 773 sages, i. 107; membrane of the fistula, first pointed out by Hunter, since described by Villerme, Laennec and Breschet, i. 108; Hunter's description of it, i. 108 ; treat- ment of the fistulous passage, i. 108; plans of treatment' recommended by Langen- beck, H. Dewar, Cramer, Walther, and others, i. 108; Langenbeck's recommen- dation of the ligature, i. 109; attention to the general health requisite during suppuration, i. 109; abscess of the tonsil, i. 159 ; opening an abscess of the tonsils with a guarded bistoury or the pharyngo- tome, i. 160; treatment after the pus has. been evacuated, i. 160; in rare cases the abscess becomes external under the jaw, i. 161; Allan Burns on the spontaneous bursting of the abscess, i. 160; it is at- tended with much danger, i. 161; details of a case in which the trachea was deluged with purulent matter, and death by suffo- cation ensued, i. 161; Burns' advice in such cases to tap the abscess with trocar and canula, l 161; in most cases of ton- sillar abscess the action of emetics will cause the rupture of the abscess; if not* it must be opened, i. 161; Burns' and" South's directions for opening a tonsillar abscess, i. 161; cases of fatal haemorrhage consecutive to opening a tonsillar abscess mentioned by Portal, Allan Burns,Tyrrell, and Brodie, i. 162; Lawrence's case of alarming haemorrhage from puncturing an immature tonsillarabscess,i. 162vabsoess of the parotid gland sometimes of con- siderable magnitude, i. 168; Evanson and Maunsell on the suppuration of mumps, i. 169; treatment of mumps after an abscess has formed, i. 169; abscess of the breast, i. 170; opening the abscess only advis- able, when it is very deep, has proceeded slowly, the pain is g?eat, and the fever high, i. 170; South's recommendation that abscess of the breast be opened freely and early, i. 171; advantages of the pro-. ceeding, i. 172; deep-seated abscesses in the mammary gland, or between it and the pectoral muscles, i. 173; to be opened early, i. 173; fistulous passages to be laid open throughout their whole length, i. 173; Astley Cooper on chronic abscess of the breast, i. 173"; South's case of chronic abscess of the breast, operated on by mis- take for scirrhus, i. 173; abscesses in the labia or nymphae, i. 180; Hunter and Ricord on abscesses complicating gonor- rhoea in the female, i. 180; suppuration of the testicle to be feared, when the in- flammation is severe, and the pain throb- bine, i. 201; suppuration of the testicle rare3, when the swelling is sympathetic, i. 202; Astley Cooper on suppuration of the testicle, 202; bursting of the abscess sometimes followed by a fungous growth, i. 202; treatment of suppuration and ab- scess of the testicle, i. 203; South on the treatment of fungus of the testicle, conse- cutive to abscess, i. 203; seat of the in- flammation in lumbar abscess, i. 207; symptoms,i.207; formation of the abscess, i. 207 ; general symptoms of suppuration not present if the abscess be not large, i. 208; Astley Cooper on the symptoms of psoas abscess, i. 208; Pearson on the symptoms preceding, and accompanying the formation of the abscess, i. 208; causes, i. 208; English surgeons generally con- sider disease of the vertebrae to be the cause, i. 208; Pott on the diseased condi- tion of the spine in this complaint, i. 208; Astley Cooper on the origin of psoas or lumbar abscess in inflammation of the spine and intervertebral substance, i. 209; Abernethy, Lawrence, and Dupuytren on lumbar abscess, generally connected with carious vertebrae, i. 209; South on the origin of the disease from external vio- lence, its origin then being in the spine, i. 209; South on the distinctive characters of psoas abscess from femoral hernia, i. 209; John Pearson on the situation of the external abscess, i. 210; Samuel Cooper's notice of Ramsden's case of lumbar ab- scess, i. 210; South on the insidious pro- gress of the disease, i. 210; abortive treat- ment of lumbar abscess, i. 210; opening the abscess, i. 211; Dupuytren on the changes that sometimes take place in the abscess, i. 211; Astley Cooper remarks, that the abscess must be allowed to take its course, i. 211; this opinion controvert- ed by South, i. 211; Cline and Aberne- thy's experiments to cause absorption of the pus, i. 211; South on issues in the treatment of lumbar or psoas abscess, i. 211; difference of opinion as to the pro- priety of waiting the self-evacuation of the abscess, or of puncturing: and emptying it, either entirely or partially, i. 212 ; Deck- ers, Benjamin Bell, and Crowther on tap- ping the abscess with a trocar, i. 212; Latta recommends the use of a seton in addition, i. 212; this latter practice con- demned by South, who prefers opening the abscess with a lancet, i. 212; Aber- nethy's plan oftreatment, i. 212; Astley Cooper and Lawrence support Aber- nethy's views, i. 213 ; Kirkland advises to let the abscess break of itself, i. 213 ; John Pearson prefers making a small aperture, and treating the ulcer in a gentle manner, i. 213; Dupuytren leaves the abscess to nature, i. 213; South's plan of treatment, i. 213; treatment to be 774' ANALYTICAL INDEXT. pursued after the abscess is opened, i. 213; Pearson and Astley Cooper on the treatment of the sinuous cavities result- ing from the abscess, by injections, i. 214; Dupuytren recommends cauteriza- tion, or weak injections of nitrate of silver, or nitric acid, i. 214; treatment of the abscess, if inflammation super- vene after it has been opened, i. 214; Abernethy on the symptoms of the super- vening inflammation, i. 214; Pearson mentions that the larger arteries some- times ulcerate into the abscess, i. 214; M'Dowell mentions a case in which ulceration took place in a portion of the ileum adhering to the cyst of the abscess, i. 214; whitlow and its varieties, i. 214; South's cases of abscesses external to the joint, i. 235; Astley Cooper and Coulson on the bursting of abscesses of the hip- joint, i. 282; Mackenzie and Scott's cases of abscesses of the hip-joint, i. 282; the abscesses to be freely opened, i. 298; Ford, Wend, van der Haar, Rust, Brodie, and Jaeger, on the treatment of these abscesses, i. 298; Sabatier and Ficher advise their being opened with caustic, i. 298; Larrey, with the red-hot trocar, i. 298; Rust, with the actual cautery, i. 298; Rust advisespassing-a seton through the joint, i. 298; Brodie and Jaeger re- commend free incisions in opening these abscesses, i. 299; Brodie and South on the management of abscesses at the hip, i. 299; subsequent treatment, i. 299; connexion of Pott's disease with lumbar and psoas abscess, i. 308; Brodie on the disappearance of psoas abscess, and its appearance elsewhere, i. 309; Brodie on abscess connected with vertebral caries in the neck, i. 315; treatment of abscess resulting from, a bruise, i. 369; abscess of the brain, i. 439 ;—see wounds of the Head; abscesses of the liver consequent on injuries of the head, i. 469; Morere and Duparcque on abscess of the womb, i» 532; abscesses about the anus, ii. 162; treatment of abscesses in the neighbour- hood of the rectum, ii. 164; Brodie on the treatment of large abscesses high up by the side of the rectum, ii. 165:; Key on abscess in the hernial sac after the operation for strangulated hernia, ii. 302, 309; abscesses by the side of the rec- tum, from the irritation of foreign bodies, iii. 108; abscess of the prostate, iii. 136; abscesses aboijt the neck of the bladder, after the operation of lithotomy, iii. 343. Acarus-scabiei, ii. 66. Acephalocysts, iii. 441. Achillis' Tendon, Division of, i. 539; tearing of the tendon, i»539>; causes and symptoms, i. 539; laceration of the sheath of the tendon, i. 539; John Hunter on rupture of the tendo Achillis, i. 540; mode of union of the ruptured tendon, i. 540; treatment, i. 540; John Hunter on the treatment of the ruptured tendon, i. 540; various bandages for the cure of the rupture, i. 541; the bandages pro- posed by Gooch, Petit, Schneider, De- sault; and Wardenburg, i. 541; Edmon- ston's plan of treatment, i. 542; the slippers of Petit, Ravaton, Monro, and Graefe, i. 542; objections to bandaging, i. 542 ; after-treatment, i. 542. Acromion, Fracture of, i. 600. Adams, Dr., on the acarus scabiei, ii. 67. Adams', Mr., case of longitudinal dis- location of the radius, ii. 232; case of hydrocephalocele treated by puncture, ii. 368. Adams, Mr. William, post mortem appear- ances in a case of hip-disease, i. 290. Addison's, Mr., artificial leg, iii. 593. Aetius on aneurism, ii. 468. Akolcthus' case of extirpation of the up- per jaw, the first on record, iii. 754. Alanson's, Mr., mode of amputation by the circular incision, iii. 640; on amputation just above the ankle, iii. 674; mode of amputating at the shoulder-joint with the circular cut, iii. 715. Alban's, M.-, apparatus for fracture of the neck of the femur, i. 623. Alcock, Mr., on the removal of the edges of the cleft in staphyloraphy, ii. 32]; mode of operating in staphyloraphy, ii. 32. Alcock, Mr. Rutherford, on the differ- ence of the shock to the-constitution in severe injuries of the extremities, when occurring in civil life and on the field of battle, iii. 725. Alibert's, M., division of boils into four kinds, i. 151; dispute with Lugol respect- ing the acarus scabiei, ii. 67; on the varieties of cancer, iii. 502. Alison, Dr., on the symptoms of inflam- mation, i. 35. Allan, Mt., on the.effects of the scorpion sting, i. 387; on compression in the treat- ment of aneurism, ii. 487; on the seat of stricture in the rectum, iii. 46; case of retention of the urine in the ureter, iii. 127. Alliot, M., on urethroplasty, ii. 179. . Alouette's, M. L\, mode of amputating at the hip-joint, by the flap cut with a single flap, iii. 691. Amesbury's, Mr., fracture-apparatus, i. 562; apparatus for fractured clavicle, i. 603; apparatus for fracture of the olecranon, i. 603; fracture-bed, i, 625*; on the for- mation of a false joint, with a. fibro- ligamentous oapsule, and a lining mem- A-NALYTICAL INDEX. ■77'5 • brane, ii. 14; on the causes of the non- union of fractional bones, ii. 14. Ammon, M. von, on the causes of congeni- tal dislocation, ii. 208. Amputation; the circumstances in gun- shot wounds requiring amputation on the spot, i. 378; Hennen on the nature of the injuries in gun-shot wounds re- quiring amputation, i. 379 ; amputation under the -circumstances mentioned should be performed early, i. 380; Wise- man, Le Dran, and Ranby on immediate amputation, i. 380; Faure on the pro- priety of delaying the operation, i. 381; Bilguer's objections to amputation alto- gether, i. 381; Hunter's objections to pri- mary amputation, i. -381; Hennen, Pit- cairn, Gunning, and -Guthrie on im- mediate amputation, i. 381 ; Guthrie's reasons for an early performance of the operation, i. 382; symptoms which may require the performance of amputation at a time more or less posterior to the date of the injury, i. 383; conditions under which amputation may be neces- sary in fractures, i. 567; Astley Cooper and Abernethy on the question of im- mediate amputation, i. 568; Sonth on the principal points to be considered in determining on the necessity for imme- diate amputation, i. -568; amputation must not be performed during the con- tinuance of symptomatic fever, i. 572; Hunter on the removal of the injured limb during the continuance of hectic, i. 572; South on the objects and occa- sional results of immediate amputation, i. 573 ; cases in which amputation is in- dicated in necrosis, ii. 131; the question as to the necessity of amputation in dislocations accompanied with tearing of the soft parts covering the joint, and thrusting out of the head of the bone, ii. 207; in compound dislocations of the knee, ii. 248 ; of the ankle-joint, ii. 251; of the toes, ii. 256; amputation requisite when mortification ensues after the liga- ture of the principal artery, ii. 500; is rarely successful, ii. 500; the question of amputation in aneurism of bones, ii. 559; amputation requisite in exostosis, when its size does not permit its removal, iii. 412; inosteosteatoma,andin osteosarcoma, am- putation should, if possible, be performed above the next joint, iii. 414; amputation requisite in some cases of spina ventosa, iii. 54; amputation of the breast, iii. 542; of the penis, iii. 544; amputations of the limbs, iii. 638; amputations divided into those which are performed in the continuity of limbs and those at joints, iii. 638; points to be considered in per- forming amputations, iii. 638; precautions against haemorrhage, iii. 638; inconve- niences of the application of the tour- niquet, iii. 638; compression of the prin- cipal artery by a capable assistant prefer- able, iii. 638; Briinninghausen's recom- mendation to swathe the limb in flannel, to diminish the loss of blood, iii. 638; South on the relative value of the tourniquet, "and of compression of the principal artery by a capable assistant in amputation, iuV638; formation of such wound that the bone can be properly covered by soft parts, iii. 639; by the cir- cular incision, iii. 639; the Celsian ope- ration, iii. 639 ; objections to this opera- tion, ih. 639 ; Petit, Mynors, Briinning- hausen, Louis, Alanson, Gooch, Bell, Desault, Richter, Boyer, Graefe, Dupuy- tren, Wilhelm, Valentin, and Portal's modes of operating, iii. 640; flap amputa- tions, iii. 641; Pott, Siebold, and Schrein- er's operations, iii. 641; Langenbeck and ScOutetten's operations for disarticula- tions, iii. 642 ; the oblique cut of Sedillot and Baudens, iii. 642 ; the sloping cut of Blasius, iii. 642; retraction of the divided museles and sawing of the bone, iii. 642; scraping off the periosteum superfluous, iii. 642; Walther and Briinninghausen's management of the periosteum, iii. 642; South on the retraction of the divided muscles by the hand, iii. 642; South and Liston on the use of the saw, iii. '643; South on the~duties of the assistant, when the bone is being sawn through, iii. 643 ; ligature of the divided vessels, iii. 643; historical sketch of the treat- ment of haemorrhage after amputation, iii. 644; South on venous haemorrhage, and the ligature of the veins after amputa- tion, iii. 644; subsequentdressing of the wound, iii. 644; leaving the wound open for some hours after the operation, to guard against after-bleeding, iii. 644; Dupuytren's practice, iii. 644; South on the exposure of the stump, iii. 645; mode of dressing to promote quick union, iii. 645 ; South on the bringing the edges of the wound together in the horizontal direction, iii. 645; South on the applica- tion of the plaster straps after amputation, iii. 646; use of cradles after amputation, iii 646; South on the use of cradles, and of a substitute for them, after amputation, iii. 646; dressing after flap-amputations, iii. 647; South on the use of sutures after flap-amputations, iii. 647 ; dressing of the stump, when intended to heal by sup- puration and granulation, iii. 647; South's objections to the practice, iii. 648; acci- dents which may ensue after amputation, 776 ANALYTICAL INDEX. iii. 648; renewal of the dressing under ordinary circumstances, iii. 648 ; mode of changing the dressings, iii, 648; with- drawal of the ligature, iii. 648 ; general treatment after amputation, iii. 648; Be- nedict's stimulant treatment of stumps, iii. 648; South on the treatment of liga- tures after amputation, iii. 648; after- bleeding, and its treatment, LK. 648; ligature of the principal. arterial trunk for consecutive haemorrhage, iii. 648; causes and treatment of parenchymatous bleeding, iii. 648 ; treatment of consecu- tive haemorrhage, from ossification or cartilaginous thickening of the arteries, iii. 649; South on the treatment of after- bleeding, iii. 649; South on the impro- priety of tying the main arterial trunk for consecutive haemorrhage after ampu- tation, iii. 649; South on the use of the actual cautery in after^bleeding, iii. 649; violent inflammation of the stump, and its treatment, iii. 649 ; erythefic-Condition of the stump, iii. 649 ; inflammation of the arteries or veins, a not infrequent cause of death after amputation, iii. 650; symptoms and treatment, iii. 650; insufficient degree of inflammation, or torpid condition of the stump, iii. 650; treatment of sloughing, iii. 650 ; of too copious suppuration, iii-. 650; causes and treatment of protrusion of the bone, iii. 650 ; South on the causes and treatment of protrusion of the-bone, iii. 651; necrosis of the bone, iii. 651 ; South on the exfoliation of bone after am- putation, iii. 651; ulceration of the bone or soft parts, iii. 651; South on the fun- ,>gous growth from the medullary cavity, iii. 651; the relative value of the several modes of proceeding in amputation of the limbs in their continuity, iii. 652; objec- tions to the'flap-operation, iii. 652; cases in which the flap-operation is suitable, iii. 653; Liston's preference of the- flap-ope- ration, and objections to the circular ope- ration, iii. 653 ; South and Fergusson on the relative value of the flap arid circular operation, iii. 653; Fergusson on ampu- tation through the calf of the leg and at the shoulder-joint, iii. 653 ; South's ob- jections to flap-operations on the leg, iii. 654; the propriety of quick union of stumps, or of the cure by suppuration and granulation, iii. 654 ; Dupuytren's mode of dressing stumps, iii. 654; South on the union of an amputation-wound, iii. 655; results of amputation, iii. 655; Phillips, Lawrie, Potter, and South on the results of amputation, iii. 656. Amputation in the continuity of the several limbs .•—am- putation through the thigh, iii. 656; pre- paratory steps of the operation, iii. 657; compression of the artery, iii. 657 ; South on the position of the limb, iii. 657 ; South on the position and duties of the assistants, iii. 657; the circular operation, iii. 657; division and retraction of the skin and cellular tissue, iii. 657; South on the circular 'Cut and vertical division of the skin laterally, iii. 658 ; section of the muscles, iii. 658; of the periosteum, iii. 658; sawing the bone, iii. 658; cutting through the muscles on the outside of the thigh, iii. 658; South on the mode of using the knife in amputating, iii. 658; South on the retraction of the soft parts with the hand, while sawing through the bone, iii. 658; bandaging and dressing the wound, iii. 658; South on bandaging and dressing the wound, iii. 659; amputation through the thigh, with twoflaps, iii. 659; mode of operating, iii. 659; Langenbeck's mode of amputating, iii. 659 ; Liston's mode of amputating the thigh, by the flap- operation, iii. 660; preferred by Syme and Fergusson,iii.668; Fergusson and South's reasons why the hind flap should be longer than the front, iii. 660; amputation through the thigh, with a single flap, iii. 660 ; Benedict, Textor, and Jaeger's plan of amputating, with.a flap from the outer side, iii. 660; Zan and Textor's plan, with a flap from the inner side, iii. 660; Hey's mode, with the flap from behind, iii. 660; B. Bell, Le Gras, and Foulliay's plan, with a flap from before, iii. 660; mode of operating, iii. 660; Dr. Little's case of amputation, with a flap from behind, iii. 660; Fergusson's recommendation to ex- cise a considerable portion of the sciatic nerve, in that operation, iii. 660; Syme's objections to amputation through the shaft of the thigh-bone, and recommendation to amputate through the condyles or tro- chanters, iii. 660; commented on by South, iii. 661 ; Liston's account of eighteen amputations through the thigh, iii. 661; report of twenty-eight amputa- tions through the thigh, iii. 662; Syme and South on the formation of conical stumps, iii. 667; Syme on amputation through the epiphyses, iii. 668; amputa- tion through the leg, iii. 668; directions for the operation, iii. 669; application of the tourniquet, iii. 669; South on the application of the tourniquet, iii. 669; modes of operating in amputation with the circular cut, iii. 669; amputation through the leg in its lower third, iii. 670; Salemi, Lenoir, and Baudens' modes of operating, iii. 670; disjointing the head of the fibula, iii. 670; Larrey's amputation through the head of the tibia, iii. 670; South on the seat of amputation through ANALYTICAL INDEX. 777 the leg, iii. 670; ligature of the vessels, iii. 671; after-dressing, iii, 671; South on the ligature of the retracted anterior tibial artery, in amputation high up through the leg, iii. 671; South on the treatment of haemorrhage from the nutri- tious artery of the tibia, iii. 671; South on the bringing the edges of the wound to- gether horizontally, iii. 671; South on the causes of subsequent sloughing of the integuments, iii. 672; amputation through the leg with a single flap, iii. 672; mode of operating, iii. 672; South's objections to flap operations on the leg, iii. 672; am- putation through the leg with two flaps, iii. 672; mode of operating, iii. 673; Lis- ton and Fergusson's mode of operating, iii. 673; amputation just above the ankle, iii. 674; Solengen, Dionis, White, Brom- field, Wright, Alanson, and Hey on this operation, iii. 674; Lawrenceand South's cases, iii. 675; Liston's statistics of ampu- tation through the leg, iii. 675; Lawrie's objection to amputation below the knee, iii. 675$ South's tabular report of ampu- tations through the leg, iii. 676; ampu- tation through the upper arm, iii. 679; steps preliminary to the operation, iii. 679; Liston's statistics of the operation, iii. 679; South on the propriety of having a long stump if possible, iii. 679; South's tabular report of amputations through the upper arm, iii. 680; amputation through the fore-arm, iii. 681; directions for the operation, iii. 681; amputation with a single flap, iii. 681; with twoflaps, iii. 681; South on flap amputations through the fore-arm, iii. 682; South's tabular report of amputations through the fore- arm, iii. 682; Liston's cases, iii. 682; am- putation through the metatarsal and me- tacarpal bones, iii. 682; application of the tourniquet, iii. 683; amputation through the metatarsal bone of the great toe, iii. 683, mode of operating when the flap is formed from the sole, iii. 683; when the flap is made from the inner side of the metatarsal bone, iii. 683 ; the bone best sawn through obliquely from within out- wards, iii. 684; mode of operating when the flap is made from the dorsal surface of the metatarsal bone, iii. 684; South on the consequences of amputation through the metatarsal bone of the great toe, iii. 684; amputation through the interme- diate metatarsal bones, iii. 685; mode of operating, iii. 685; amputation through the metacarpal bones, iii. 6S5; amputa- tion through the metacarpal bone of the thumb, iii. 686; South and Liston on amputation through the metacarpal bones, iii. 686; amputation through the fingers Vol. iii.—66 and toes, iii. 686; amputation through the phalanges of the fingers, iii. 686; mode of operating, iii. 686; cutting off the finger with a chisel, iii. 686 ; Mayor on the amputation of the phalanges with the tachytome, iii. 686; exarticulation or amputation through the joints, iii. 686; cases in which exarticulation is required, iii. 687; Scoutetten's mode of operating, iii, 687; general directions, iii. 687; con- dition of the parts around the joint, iii. 687 ; exarticulation of the thigh at the hip, iii. 688; danger and statistics of the operation, iii. 688; Jaeger, Krimer, and South on the operation, iii. 688; cases requiring the operation, iii. 688; La Croix d'Orleans, Perrault, and H. Thomson's cases, iii. 689; the modes of operating, iii. 689; by the circular cut, iii. 689; Abernethy, Veitch, Cole, Jaeger, Kerr, and Graefe's modes of operating, iii. 689; by the flap-cut with a single flap, iii. 691 ; Puthod, Hunczorsky, Bryce, L'Alouette, Langenbeck, Delpech, Le- noir, Plantade, and Manec's mode of operating, iii. 691; with two flaps, iii. 691; Blandin, Larrey, Mott, Dupuytren, Lis- franc, von Walther, Vohler, Bell, Be- clard, Liston, Begin,and Sanson's modes of operating, iii. 692; the oval cut, iii. 696; Sanson, Guthrie, Scoutetten, and Corneau's modes of operating, iii. 698; the preference given to Larrey's opera- tion, iii. 698; after dressing, iii. 698; exar- ticulation of the leg at the knee, iii. 699 ; opinions respecting the propriety of the operation, iii. 699; Jaeger's statistics of the operation, iii. 699; modes of operating, iii. 699; amputation with the flap-cut, iii. 699; Blandin, Rossi, Maingault, and Kern's operations, iii. 699; the circular cut, iii. 700; Velpeau, Cornuau, and Bau- dens' operations, iii. 700; the operation when the knee-cap is diseased, iii. 700; exarticulation of the ankle-joint an infe- rior operation to amputation through the leg, iii. 700; exarticulation of the foot at the ankle, iii. 700; Velpea-u, Baudens, Syme, and Handyside's modes of opera- ting, Hi. 702; Syme on the advantages of this operation, iii. 702; exarticulation of the tarsal bones, iii. 703; the operation re- stricted to the removal of the astragalus and navicular bones, iii. 703; Hammond's case of exarticulation of the astragal us, iii. 703; Green's case, iii. 703; general di- rections for the operation, iii. 703; am- putation of the foot between the astragalus and navicular bones, and the heel and he treatment of burns, i. 13-1; employed by him in cases of old and recent burns, vesicated and sphacelated, i. 131; pre- paration of the cotton, i. 132. Anderson's, Mr., operation for tying the common iliac, ii. 533 ; operation for tying the external iliac, ii. 534; on the ligature of the external iliac, ii. 538. Andkal's, M., objections to the term in- flammation' and substitution of the term hyperaemia, i. 33. Andrews' Mr., case of penetrating wound of the chest with injury to the lung, i. 485. Anel's M., operation for aneurism, ii. 487. Aneurisms :—definition and varieties, ii. 468; Galen, Aetius, and Paul of iEgina on aneurism, ii. 468 ; John Hunter's de- finition of aneurism, ii. 469; distinction between true and false aneurism, ii. 469 ; Breschet on the four principal kinds of true aneurism, ii. 469; symptoms of aneurism, ii. 469; John Hunter on the coagulation of blood in an aneurism, ii. 470 ; John Hunter and Hodgson on the bursting of aneurisms, ii. 470 ; bursting of aneurisms into mucous canals, ii. 471; Dr. Wells' case of an aneurism bursting into another artery, ii. 471; distinguishing characters of circumscribed true and false aneurism, ii. 472; Lawrence on the bruit de soufflet, ii. 472; South on the distin- guishing characters of circumscribed true and false aneurism, ii. 472; diagnosis of aneurisms from other swellings, ii. 472; Dupuytren, Ferrand, Astley (fooper,and. 780 ANALYTICAL INDEX. South's cases of aneurism mistaken for abscess, ii. 474; Warner's case of abscess mistaken for aneurism, ii. 474; causes of aneurism, ii. 474; Richerand on the occurrence of aneurism in the dissecting- room servants, ii. 474; Guthrie on the predisposing cause of aneurism, ii. 473; Astley Cooper on the age at which aneu- rism occurs, ii. 475; John Hunter, Astley Cooper, Hodgson, Guthrie, Lisfranc, and South on the relative frequency of aneu- rism in the sexes, ii. 475 ; relative fre- quency of aneurism in the arteries, ii. 476 ; Hunter, Hodgson, and Lisfranc on the relative frequency of aneurism in the arteries, ii. 476; more than one aneurism may exist at the same time, ii. 476; Cline and Astley Cooper's cases, ii. 476; Astley Cooper, Tyrrell, Pelletan, and Cloquet's cases of the existence of nume- rous aneurisms in the same person, ii. 477 ; condition of the arterial'coats in an aneurism, ii. 477 ; John Hunter admits a diseased condition of the artery as the cause of aneurism, ii. 477; Scarpa's views respecting the non-expansion of all the arterial coats in aneurism not always cor- rect, ii. 477; spontaneous cure of aneu- rism, ii* 478 ; circumstances which favour spontaneous cure, ii. 478; John Hunter and South on .the spontaneous cure of aneurism, ii. 479; mode of cure of aneu- rism, ii. 479; enlargement of the col- lateral circulation, ii. 479 ; remedies for the treatment of aneurism, ii. 479 ; treat- ment of internal aneurism op Valsalva's plan, ii. 479; application of astringent remedies to restore the elasticity of the arterial coats, ii. 480; Guerin, Richerand, and Hodgson on the application of pounded ice to aneurism, ii. 480 ; com- pression, ii. 480; of the swelling alone objectionable, ii. 480; of the artery above the swelling, ii. 481; of the whole limb, ii. 481; Guattani's plan of treating aneu- rism by compression, ii. 481; John Hunter, Sir W. Blizard, Freer, Hodgson, Richerand, Hutton, Bellingham, Liston, Allan, Greatrex, and Crampton on com- pression in the treatment of aneurism, ii. 482, 483, 484, 4S5, 486; cases in which compression may be had re- course to, ii. 486; S. Cooper on the effects of compression in aneurism, ii. 487; ligature of the aneurismal artery, ii. 487; Anel's operation, ii. 487; Desault's case, ii. 488; the Hunterian operation, ii. 488; Hunter's claims to originality in reference to this operation, ii. 488; Ford's eases of spontaneous cure, ii. 489; Sir E. Home on the Hunterian operation, ii. 490; indications for the operation, ii. 490; Sir E. Home on the non-necessity for the existence of large collateral branches, to ensure success in this opera- tion ii. 491 ; Hunter and South on the size of the aneurism best fitted for ope- ration, ii. 491; the operation for aneurism by opening the sac, ii. 491; the Hunterian operation, ii. 491; Scarpa and Jones on the application of the ligature, ii. 492; Jones, Hodgson, Travers, Scarpa, Law- rence, Astley Cooper, Maunoir, and Aber- nethy on the effects produced by the liga- ture on the arterial coats, ii. 492,493; John Hunter's operation for tying the femoral artery in popliteal aneurism, ii. 493; Birch's case, ii. 494; South on the im- portance of opening the sheath to the least possible extent, in applying a ligature round an artery, ii. 495 ; Cline's cases in which the femoral artery was tied with a broad tape, the ligature being removed some hours after, ii. 496 ; Crampton and Dease's cases in which the temporary ligature was employed!, ii. 496; Lisfranc on the ligature of a diseased artery, with- out opening the sheath, ii. 496 ; Aberne- thy and Galen on the application of two ligatures, and the division of the artery between them, ii. 497; treatment after the operation, ii. 497; W'edemeier's case in which the aneurism burst after the ligature of the femoral artery, and ampu- tation became requisite, ii. 497 ; Guthrie and South on the return of pulsation in the aneurism for a short time, after the li- gature of the artery, ii. 497, 498; Green's Gase, ii. 498; accidents consecutive to the operation — secondary hemorrhage and mortification, ii. 498; circumstances un- der which secondary hemorrhage is likely to oceur, ii. 498 ; Hunter*s cases of secondary hemorrhage after the opera- tion, ii. 498 ; Green's case of secondary hemorrhage after the ligature of the sub- clavian, ii- 498; South on the treatment of secondary hemorrhage, ii. 499 ; Gun- ning and Briggs' cases of recurrence of the aneurism after the ligature of the ar- tery, ii. 499; occurrence of mortification of the limb, after the ligature of its prin- cipal arterial trunk, ii. 500; causes, ii. 500; advantages and disadvantages of the old operation for aneurism, ii. 501; advantages of the Hunterian operation, ii. 501 ; the Hunterian operation not applica- ble in certain forms ofaneurism, ii. 501; Thierry and Lieber on torsion of the artery, ii. 501; Amussat's division and thrusting back the internal coats of the artery, ii. 502; mode of operating, ii. 502; Tavignot's subcutaneous tying the super- ficial arteries, ii. 502;. changes effected ANALYTICAL INDEX. 781 in arteries by the application of a> liga- ture, ii. 502; cutting into and plugging the aneurism, ii. 50#; suture of arterial wounds, ii. 503 ; application of a ligature with a running knot; ii. 503; E. Home and Phillips on acupuncture of the aneur- ism, ii. 503 ; Velpeau on acupuncture of the artery, ii. 503; Pravaz on acupunc- ture of the sac, and the application of galvanism, ii. 503; cauterization with moxas, ii. 503; introduction of mechani- cal plugs into the arteries, ii. 503; of threads, ii. 503; various modes of com- pression, ii. 503; Brasdor's operation, ii. 503; Deschamp's case, ii. 504; Astley Cooper's case, ii. 504; Wardrop and Lawrence on Brasdor's operation, ii. 504; aneurism of the carotid artery and its branches, ii. 507 ; situation and diagnosis, ii. 507; Burns' and Syme on carotid aneurism, ii. 507; compensation of the cerebral circulation after ligature of the carotid, ii. 507 ; Macgill and Mussey's cases of ligature of-both carotids, ii. 507 ; Abernethy's case of ligature of the inter- nal carotid on account of a wound, ii. 508; Fleming's case of ligature of the carotid | for secondary hemorrhage, ii. 508; Ast- ley Cooper's case of ligature of the com- mon carotid, ii. 508;.Travers, Robertson, and Zfeis'cases of ligature of the carotid, ii. 508 ; Kurd's- case of ligature of both carotids, ii. 508 ; tying the common caro- tid may be performed at three different places, ii. 509-; mode of operating imme- diately above the eollar-bone, ii. 509; Zang, Dietrich, and Coates on ligature of the common carotid, ii. 509 ; the ope- ration below the omo-hyoideus, ii. 510; Astley Cooper on the impediment to the operation offered by the internal jugular vein, ii. 511; if the vein be wounded, it must be tied, ii. 511 ;the operation above the omo-hyoideus, ii. 511; after-treat- ment, ii. 511; Astley Cooper on the post- mortem appearances in a case in whieh he had tied the common carotid 13 years before, ii. 512; aneurism of the branches of the carotid, ii. 512; tying the external carotid, ii. 512; Dietrich on.the ligature of the external carotid, ii. 512; Beclard and Dietrich on the ligature of the lingual artery, ii. 513; ligature of the external maxillary or facial artery, ii. 514; Vel- peau and Dietrich on the ligature of this artery, ii. 514; aneurism of the tem- poral artery, ii. 515; ligature of the ar- tery, ii. 515; aneurism of the occipital artery, ii. 515; its ligature, ii. 515 ; liga- ture of the posterior aural, ii 515; Astley Cooper's case of aneurism of the posterior aural, ii. 515; Begin's case of aneurism 66 of the middle meningeal artery, ii. 515; aneurism of the branches of the internal carotid in the skull, ii. 515 ; Sir Gilbert Blane's case of aneurisms of the internal carotid by the side of the sella turcica, ii. 516; Hodgson's case of aneurism of the anterior cerebral, ii. 516 ; Serres' case of aneurism of the basilar, ii. 516; aneurism of the subclavian and axillary arteries, ii. 516; characters of axillary aneurism, ii. 516; ligature of the axillary artery, ii. 546; two modes of Operating, ii. 516; the operation by cutting through the pecto- ralis major, ii. 516; the operation by di- vision of the tendinous interspace be- tween the pectoral and deltoid muscles, ii. 517; South's objections to both these operations, ii. 517; ligature of the sub- clavian above the collar-bone, ii. 518; Dupuytren, Hodgson, Lisfranc, and Graefe on the section of the scalenus an- ticus in ligature of the subclavian, ii. 518; Astley Cooper, Ramsden, Sir W. Blizard, T. Blizard, Dr. Colles, Dr. Post, and Liston's cases of ligature of the subclavian above the clavicle, ii. 518; 519; Green and South on ligature of the subclavian, ii. 519; ligature of the sub- clavian on the tracheal side of the scale- nus, ii..519; the operation very hazard- ous, ii. 520; mode of operating, ii. 520; Dietrich's description of the operation, ii. 520; South on aneurisms of the aorta and origin.of the carotid and subclavian, liable to be mistaken for aneurism of the subclavian, ii. 521; Allan Burns and Hodgson's proposal to tie the innominata, ii. 521; Mott and Graefe's operations, ii. 521; Hodgson on ligature of the innomi- nata, ii. 522; Bujalsky, King, Dietrich, and Manec on ligature of the innominata, ii. 522; compensation to the circulation, when the subclavian is obliterated, ii. 524 ; Key on the post mortem appearances in a case in which he tied the subclavian 12 years previously, ii. 524; South on the results of injury to the axillary nerves, ii. 525; ligature of the internal mammary, ii. 525; Dietrich's description of two modes of tying the vertebral ar- tery, ii. 526; Nuntiante Ippolito on liga^ ture of the vertebral artery, ii. 527; Mo- bus' case of vertebral aneurism, ii. 527: case of vertebral aneurism, ii. 527; aneur- ism, of the brachial, ulnar, and radial ar- teries, ii. 527; causes of aneurism of the brachial, ii. 527; Astley Cooper, Hodg- son, and Liston on the spontaneous aneurism of the brachial, ii. 528; the free anastomosis of the arteries of the arm requires the ligature of the artery near the sac, ii. 528; Astley Cooper and 782 ANALYTICAL INDEX. Liston on ligature of the arteries of the fore-arm, ii. 528; W. Cooper's case of radial aneurism, ii. 528; aneurism, on the back or front of the hand, ii. 528; liga- ture of the brachial, ii. 528;. the operation in the arm-pit,.ii. 528; in the middle of the upper arm, ii. 529; high bifurcation of the brachial, ii. 529 ; Tiederaann on the high bifurcation of the brachial, ii. 529; ligature of the brachial, at the bend of the arm, ii. 529"; of the radial in the upper third of the fore-arm, ii. 529; of the ulnar,in the upper third of the fore- arm, ii. 530;. in the lower part of the fore-arm, ii. 530;. in the region of the wrist, ii, 530; ligature, of the end of the radial artery, .ii. 530;; compensa- tion to the circulation after ligature of the brachial, ii, 530; White and South on the compensating collateral branches, ii., 531; aneurism of the external and inter- nal iliac, ii. 531; Astley Cooper, James, and Murray's cases of ligature of the aorta, ii. 531;. Guthrie on ligature of the aorta, ii, 532; Monteiro's case of ligature of the aorta, ii. 532; ligature of the com- mon iliac for aneurism, of the external or internal iliac, ii. 532; the operation for ligature of the common iliac, ii. 532; Mott, Crampton, Anderson and Salamon's operations, ii. 533; ligature of the inter- nal iliac for aneurism of its branches, ii. 533; the operation for ligature, of the in- ternal iliac, ii. 533; Stevens, White, An- derson and Bujalsky's operations, ii. 534; Owen on the post-mortem appearancesin Stevens' case, ii. 534; ligature of the gluteal, ii. 535; Carmiehael's case, ii. 535; ligature of the ischiatic, ii. 535; of the common pudic, ii. 535; case of aneurism of the internal pudic, ii. 535; aneurysm of the femoral an4 popliteal ar- teries and their branches ii. 535; Aber-. nethy's ease of ligature of the external iliac in the groin, ii. 535; Freer and Astley Cooper's cases, ii. 537; Tait and Arendt's cases, of ligature of both the. ex- terhal iliacs, ii,.537; cases in which the external iliac should oe, tied,.ii. 537; description of the operation,, ii.. 538; Abernethy, Charles Bell, Scarpa, Astley. Cooper, Lisfranc, Anderson, Rust, Lang- enbeck, Delpech,Wright, Post,Bujalsky, and Guthriq on the ligature of the exter- nal iliac, if 538; the. operation for liga- ture of the femoral below Poupart's liga- ment, ii. 539;. Textor and; Froriep on ligature of the femoral below Poupart's ligament, ii. 539; compensation to the . circulation after ligature of the external iliac, ii. 540; Astley Cooper on the post- mortem appearances after; ligature of, the external iliac, ii. 540 ;• ligature of the femoral, for aneurism in the lower third of the thigh, or at the knee-joiht, ii. 541; John Hunter on ligature of the femoral, ii. 542; ligature of the popliteal danger- ous, and-not to be practised, except for wounds, ii* 542; the operation in the middle of, the ham, ii. 542; in the upper part of the ham, ii. 542; in the lower part, ii. 542; Jobert's case of ligature of the popliteal in the internal epicondyloid pit, ii. 543; aneurism of the tibial artery, ii. 543; Green's case of aneurism of the posterior tibial, ii. 543; Astley Cooper and Cline jun.'s cases of aneurism of the anterior tibial, ii. 543; Astley Cooper on the treatment of aneurism of the anterior tibial low down, by opening the sac, and tying the artery above and below, ii. 544; ligature of the anterior tibial above the middle of the leg, ii. 544; in the neigh- bourhood of the instep, ii. 544; of the posterior tibial in the middle or upper thirds of the leg, ii. 544; South on liga- ture of the posterior tibial when wounded ii. 544; ligature of the peroneal artery in the middle of the leg, ii. 544; aneurisms in the sole and back of the foot, ii. 545; compensation to the cir- culation, when the femoral artery has been tied, ii. 545; Astley Cooper on the post-mortem appearances after liga- ture of the femoral artery, ii. 545; aneurismal varix and varicose aneurism, ii. 546; definition of an aneurismal varix, Li. 546; McMurdo's case of aneurismal varix between the internal jugular vein and carotid artery, ii. 546 ; characters of the disease, ii. 546; Breschet on the con- dition of the artery and vein in aneuris- mal varix, ii, 547; Sennertus, Galen, and William Hunter on .aneurismal varix, ii. 547; Lawrence and Liston on the pecu- liar, noise heard in an aneurismal varix, ii. 549;-Liston's case of aneurismal varix in the femoral vein and artery, ii. 549; W. Hunter on the distinction between aneurismal varix, and false aneurism. ii. 549; treatment, ii. 549; Breschet, Stromeyer, and Astley Cooper on the treatment of aneurismal varix, ii. 550; Atkinson's ligature of the brachial artery for aneurismal varix, ii. 550;. varicose aneurism, ii. 550; definition, ii. 550; W. Hunter on varicose aneurism, ii. 550; the operation, ii. 551; Green's case of varicose aneurism,, ii. 551; Perry's case of aneurism bursting into a vein, ii. 551 ; South's comments on the case,ii. 551; 'unnatural expansion in th&branches and ramifications of arteries, ii. 552; branching aneurism, ij. 552; seat and ANALYTICAL INDEX. 783 characters, ii. 552 ; diagnosis from other [Arendt, M.'s, case of ligature of both the swellings, ii. 553; causes, ii. 553; prog- nosis, ii. 553; treatment, ii. 553; Graefe, Travers, Dalrymple, Wardrop, Rogers, and Dupuytren on the treatment of branching aneurism, ii. 554; aneurism of the arteries of bone, or aneurism by, anas- tomosis of bone, ii. 554; symptoms, ii. 554; post mortem appearances, ii. 555; situation, ii, 555; occasional causes, ii. 555; these aneurisms always preceded by inflammation of the bone, ii. 556; Stanley on pulsating tumours of bones, ii. 558; treatment, ii. 558; unnatural ex- pansion in ihe capillary-vascular system, ii. 559 ; teleangiectasy, \u 559;: is con- genital, ii. 559 ; characters, ii. 559 ; fun- gous gowths after rupture of the swel- ling, ii. 560; nature of the disease, ii. 560; complications, ii. 560; teleangiectasis lipomalodes, ii. 560; oauses,ii. 560; always, a local disease, ii. 561; prognosis, ii. 561; treatment, ii. 561; by compression, ii. 561; Abernethy on compression, ii. 561; by extirpation with the knife, ii. 561; with the ligature, ii. 562; ad- vantages of the ligature, ii. 562; Law- rence, Brodie, and South on the appli- cation of the ligature, ii. 562; destruc- tion of teleangiectasy by caustie, ii. 563; South on caustic in teleangiectasy, ii. 564; various remedies to induce inflammation and suppuration in the diseased growth, ii. 564; Pattison, Smith, and Tyrrell's cases, ii. 564; tying the principal trunk supplying the diseased growth, ii. 566; if the teleangiectasy be seated in the extremities, and incurable, amputation must be performed, ii. 566; Pauli on the tattooing of moles on the skin, ii. 566. Ansiaux, M., on the application, of the ac- tual cautery in irreducible prolapse of the rectum, ii. 404. Anus, artificial ii. 152 ; spasmodic contrac- tion of, and anal fissures, ii. 171; fiist clearly described by Boyer, Dupuytren, and Brodie, ii. 171; Boyer and Dupuy- tren on the symptoms of anal fissure, ii. 171; Brodie on spasmodic contraction of the anus, ii. 172; Dupuytren on the three varieties of fissures, ii. 172; Brodie on the spasmodic contraction of the sphincter, attended with ulceration ii. 172; Dupuytren, Brodie, and Boyer on the treatment, ii. 172; Boyer's operation for anal fissure, ii. 173; anus imperfo- rate, iii. 34; congenital narrowing of, iii. 38; spasmodic contraction of, iii. 39. Aorta, cases of ligature of, ii. 531. Arden, John of, mentions the chaudepisse, i. 184; prescription for an injection for gonorrhoea, i. 190. external iliacs, ii. 537. Arm, upper, amputation through, iii. 679; exarticulation of, at the shoulder, iii. 711. Arnaud's, M., apparatus for fracture of the neck of the femur, i. 624; on the reduction en masse, ii. 274; on incision of the hernial sac, and introduction of lint-tents for its radical cure, ii. 283;- on dilatation of the stricture in strangulated hernia, without cutting, ii. 298. Arnott's, Dr., oil-silk tube for strictures of the urethra, iii. 77; on cauterizing the walls of the stricture, iii. 79 ; operation of lithectasy, iii. 375-. Arnott's, Mr., case of-liospital gangrene, i. 83 ; on severe phlebitis, i. 93; on the morbid appearances in phlebitis, i. 95 ; case of foreign body in the vagina, the bladder injured, and formation of a cal- eulus, iii. 249; case of malignant tumour of the tongue, in which that organ was removed by ligature, iii. 521; case of dis- eased undescended testicle, iii. 558. Arteries, Wounds of, and their con- sequences, i. 329; closure of slight and, longitudinal wounds of, i. 330; Saviard, Petit, and Scarpa on the healing of, wounds of, i. 330; artery compressors of Langenbeck, Verdier,Mohrenheim, Dahl, Wegehausen, Moore, Graefe, Scultetus, Heister, Dionis, Plattner, Brambilla, Desault, Leber, Ayres, Bell, Chabert, Lampe, Faulquier, Schendler, Hessel- bach, and Joachim, i. 331; von Winter's directions for wounded arteries, i. 333; pressure on the meningeal artery.inad- missible, and not requisite, i. 333; Aber- nethy's ease of wounded meningeal ar- tery, i. 333; South on Wounds* of the pudic artery and artery of the bulb, during the lateral operation for the stone, i. 334; South on the treatment of wounded arteries in the thick fleshy partsofthe hand or foot, i. 334; ligature of arteries, i. 335; South's experiments on the carotid of a dog, Lj 335; Manec, Du- puytren, and Roux on the introduction of a.piece of bougie into an ossified artery, after amputation, i. 336; treatment of a retracted artery, i. 337; South on the ligature of large arteries above and below the; wound, i. 337; South on the necessity for cutting down upon a wounded vessel on. the sound side of a limb, if nearer the artery than, is the part wounded, i. 337; Travers' case of wound of the posterior tibial artery, i. 338; Lawrence, Hennen, Delpech, Wal- ther, Haire, Guthrie, and' South on the after-management of the ligature, i. 338, 339; Dr. M'Sweeny on the silk-worm-gut ligature, i. 339; Physick on the animal )AL INDEX. 784 ligature, i. 339; Astley Cooper on the catgut ligature, i. 339; length of time before the separation of a ligature, i. 340; Callaway and Guthrie's cases, i. 340; se- condary haemorrhage on the separation of aligature,i. 340; Green's caseof secondary haemorrhage after ligature of the subcla- vian, i. 340; torsion of twisting or ar- teries, i. 341; Galen, Amussat, Thierry, Liber, Velpeau, Fricke, and Dieffenbach, on torsion, i. 341 ; changes produced by torsion, i. 341; Palmar on the torsion of arteries, i. 341; Amussat, Thierry, and Fricke on the mode of practising torsion, i. 342; Dieffenbach's torsion-forceps, i. 342; Kluges's torsion apparatus, i. 342; advantages of torsion, i. 342; Dupuy- tren, Lorch, Textor, Fricke, Elster, and Bramberger on the effects of torsion, 1. 343; Dieffenbaeh, Dupuytren, and Che- lius' objections to torsion, i. 344; South on torsion, i. 344; Feme and Astley Cooper's cases of accidental torsion, i. 344; cases in which torsion is preferable, i. 344; Kohler and Fricke on the torsion of bony vessels, i. 344 ; Stilling on the interweaving of arteries, i. 344; use of astringent styptics, i. 345; effects of cauterization on wounded vessels, i. 346; occurrenee and management of secondary haemorrhage, i. 346; circumstances fa- < vouring the occurrence of secondary haemorrhage, i. 346; Cline jun.'s cases of after-bleeding, in which the actual cautery was employed, i. 347; Cline jun.'s clinical observations on after- haemorrhage, and the use of the actual cautery in such cases, i. 347; Cline jun.'s experiments on arteries, i. 351 ; South on the treatment of bleeding os- sified arteries, ii. 352; if a large artery be wounded from a bruise, it may be necessary to expose it and take it up, i. 369; South on extensive ecchymosis, and the means of diagnosis, when an artery, of any material size has been wounded, i. 369; South on the danger of gangrene when a large artery has been wounded, from the distention of the soft parts, L 369. Arteriotomy, iii. 611. Arteritis, Dupuytren and Cruveilhier on, as a causa of dry gangrene, i. 72; South's case of, without gangrene, i. 73; in- flammation of the coats of arteries, u 88; Bouillaud on arteritis, i. 89 ; Hodg- son's cases of, u 89; Portal's case of in- flammation of; the aorta, consequent on the recession of measles, i. 89; South's case of arteritis, i. 89. Arthur, Dr., on the use of the seton in gun-shot wounds,to bring away separated pieces of bone, L377. Assalini, M., on the stanching the bleeding from a wounded intercostal artery, i. 492; Ashwell, Dr., on the extirpation of ova- rian cysts, iii. 215; on the pain in cancer uteri, iii. 563; case of cancer uteri, iii. 563; on the period of life at which can- cer uteri is generally developed, iii. 564. Astragalus, dislocation of, ii. 251; case of exarticulation of, iii. 703. Atkinson's, Mr., case of ligature of the brachial artery, for aneurismal varix, ii. 550. Attenburrow's Mr., case of trepanning the spine, i. 500; cases of old men ope- rated on for- stone, iii. 297. Atti, M., on the use of a canula, for main- taining the patency of the artificial duct, in the operation for salivary fistula, ii, 148. Aube, M., on the contagion of itch* de- pendent on the itch-mite, ii. 65. Aumont's, M;., operation for extirpating the testicle, iii. 556. Austin, Mr., on. the formation of urinary calculi, iii. 237.- Autenrieth's, M., opinion, that crusta serpiginosa is connected with itch, ii. 63. Avenzor, on the acarus scabiei, ii. 66, Avicenna, on congenital dislocation of the hip, ii. 207; on the application of caustic, , for the fadieal cure of hernia, ii. 283. Axillary aneurism, ii. 5,16. ---------artery, ligature of, if. 517. Ayres', Mr., arteryrcompressor, i. 331. Barington*s Dr., case of fatal bayonet- wound of the heart, i. 499< BabingtoN's, Mr., case, illustrative of the peculiar delirium of hydrophobia, i. 407; on the prernonitory^pains of hydropho- bia, i. 408. Bach, M., on extirpation of bronehocele by ^ligature, iii. 398. Bacot's Mr., objection to the exhibition of corrosive sublimate in cases of syphilis in infants, ii. .106 ; on,erethismus mer- curialis, ii. 109; on the cachexia syphi^ loidea, ii.-110; on the ecaema mercuriale, ii. Ill; on the treatment of mercurial sore-throat, iii 113,' Baillik's, Dr., case of obliteration of the vena cava inferior, ii, 569.. Baillie, Mr., on the local treatment of fractured ribs, i. 599. Baillif's, M., apparatus for fracture of the patella, i,. 633 ; artificial hands, iii. 595. Baines, Mt., on the treatment of vesico- vaginal fistula, by drawing off the urine, and by compression, ii. 189. Baker, Mr., on the existence of the acarus scabiei, ii. 65. Balanitis, or external gonorrhoea, i. T98; ANALYTICAL INDEX. 785 causes and symptoms, i. 198; Hunter and South on balanitis, i. 198 ; treatment, i. 198; Ricord and South on the treat- ment of balanitis, i. 199. Balfour's, Dr., case of reunion of divided parts, iii. 581. Balling, M., on cutting away the tunica vaginalis, iii. 230. Banks', Sir Joseph, account of his suffer- ings, and of Dr. Solander's, from ex- posure to cold, i. 145. Banner's, Mr. case of extirpation of the womb, iii. 570. Bardsley's, Dr., case of hydrophobia, oc- curring twelve years after the bite had been inflicted, i. 404 ; his opinion that the disease was not hydrophobia,, i. 404; supports his views by the opinions of Darwin,. Haygarth, and R. Pearson, i, 404; case illustrative of the peculiar delirium of hydrophobia, i. 407 ; on the stages of hydrophobia, i. 408; on the diagnosis of tetanus from hydrophobia, i. 418. Barlow, Mr., on the treatment of torn muscles, i. 543. Barnes', Dr., case of knife-swallowing, iii. 103. Barnes', Mr. obturator for vesico-vaginal fistula, ii, 189. Baron's, Dr., case of hydrocephalocele, ii. 470. Barry, Sir David, on the application of the cupping-glass over snake-bites, i. 391. Barry's, Mr., case of accidental reduction of the dislocation in hip-disease, i. 299. Barthelemy, M., on the means of pre- venting the retraction of the urethra in amputation of the penis, iii. 546 ; case of reunion of divided parts, iii. 581; on the section of the palmar, aponeurosis, after exarticulation of the fingers from the metacarpal bones, iii. 723. Barton's, Dr., operation, of cutting out a wedge-shaped piece of bone for the relief of anchylosis, i. 275; operation for the establishment of a false-joint, in treating anchylosis, i. 275; on the symptoms produced by the bite of the rattlesnake, i. 392 ; on the treatment of rattlesnake- bites, i. 395 ; on the employment of the ligature in snake-bites, i. 396; case of cure of ununited fracture, ii. 17; operation on the anchylosed femur, iii. 19; operation to remedy the opening of the rectum into the vagina, iii. 36. Basedow, M., considers dissection wounds agree with malignant pustule, i. 385. Bateman's, Dr., distinction between ery- thema and erysipelas, i. 116; acute erysipelas, the vesicular erysipelas of Chelius, i. 116; erratic erysipelas, the erythema symptomaticum of Chelius, i. 118; cedematous erysipelas, the ery- sipelas from scalp»wounds, L 118; on purpura haemorrhagica, or land-scurvy, ii. 49; on the existence of the acarus scabiei, ii. 67; case of erythismus mer- curialis, ii. 108; on eczema rubrum, ii. 109. Baddelocque, M., on the mode of perform- ing the Caesarian operation, iii. 162. Baudens', M., oblique cut in amputations, iii. 642; mode of amputating the leg in its lower third, iii. 670; mode of ampu- tating at the-knee with the circular cut, iii. 700; at the ankle-joint, iii. 700; mode of operating in exarticulation of the fore- arm at the elbow, iii. 720. Bauer, M., on the presence of globules in the serum, i. 56. Bayle,M.,on mortification from spurred rye, i. 74; on the pain in cancer uteri, iii. 562. Baynham's, Mr., case of puncturing the womb, in retroversion, ii. 412. Beaumont, Mf., on increased pressure and supine posture in the radical cure of her- nia, iik 282. Beck's, Mr., apparatus for fracture' of the neck of the femur, i. 624; on accidental cerebral rupture, ii. 365. Beckett's, Mr., memorandum respecting gonorrhoea, i. 183; prescription for an injection for gonorrhoea, i. 190. Beclard, M., distinctly of opinion that cartilages are not vascular, i. 253 ; prac- tice in wounded intestine, ii. 509 ; on the treatment of fistula of the parotid duct, ii. 149 ; on the ligature of the lingual artery, ii. 513 ; modification of Dupuytren's bi- lateral section for stone, iii. 327; mode of amputating at the hip-joint with two flaps, iii. 692; mode of amputating at the shoul- der-joint, iii. 716. Bedingfield, Mr., on the treatment of tooth-ache, ii. 138. Beer's, M., cases of malignant pustule, i. 79. Begin's, M., case of closing and wasting of the portion of intestine below the artificial anus, ii. 153; case of aneurism of the middle meningeal artery, ii. 515 ; opera- tion for the division of the inner fold of the prepuce, iii. 57 ; directions for ceso- phagotomy, iii. 100; on the treatment of complete retention of urine in stricture, iii. 145; on the operation for cutting into the urethra in the perinaeum, iii. 147; mode of amputating at the hip-joint with two flaps, iii. 698; mode of operating in excision of the knee-joint, iii. 740. Beinl's, M., opinion, that the so-called lymph-swelling is an extravasation of 786 ANALYTICAL INDEX. lymph, i. 60; plan of opening a cold abscess with a lancet, after the previous application of caustic, i. 105. Bell, Mr. Benjamin, denies the identity of gonorrhoea and syphilis, i. 185; cases of gonorrhoea of the nose, i. 199; on alter- nate swelling of the testicles, i. 199 ; on tapping lumbar or psoas abscess with a trocar, i. 212; on the stanching the bleed- ing from a wounded intercostal artery, i » 492 ; on the use of the suture in wounded intestine, i. 512; on the expulsion of the suture after union has taken place, i. 514 ; apparatus for fraeture of the patella, i. 633; objections to the use of the catheter in urethral fistula, ii. 182; mode of am- putating by the circular incision, iii. 640; plan of amputating the thigh with the flap from before, iii. 660; mode of ampu- tating at the shoulder-joint with the cir- cular cut, iii. 715. Bell's, Sir Charles, opinions relative to the formation of pus, i. 46; on tying the tonsils,!. 164; case of hysterical affection of the hip-joint, i. 277 ; explanation of the pain in the inside Of the knee in hip- disease, i. 280; on the pain in hip-disease, i. 289; on morbus coxae senilis, i. 289; proposal to sawthrough the neck of the fe- mur in hip-disease,to promote anchylosis, i. 299 ; on the operation for trepanning the spine, i. 590, 592; objection to laying open the fracture and using the elevator, or removing its edge by the lenticular, in order to raise the depressed portion of bone in fracture of the sternum, i. 598 ; on the bent position in fracture of the femur, i. 628; operation for the restora- tion of the canal of the urethra, ii. 181; on the mode of reducing the dislocation of.the thumb, ii. 235 ; on the reduction en masse, ii. 274; on the ligature of the ex- ternal iliac, ii. 538; oh the ligature of the spermatic veins in varicocele, ii. 578 ; on the seat of stricture in the rectum, iii. 44 ; mode of amputating at the hip-joint with two flaps, iii. 692. Bell, Mr. John, on the arrest of haemor- rhage by nature, 329; artery-compressor, i. 331; on the use of the suture in wounded intestine, i. 512. Bellanger, M., on the reduction of the re- troverted womb, ii. 412. Bellingham, Dr., on compression in the treatment of aneurism, ii. 486. Bellini's, M., operation for prolapsus uteri, ii. 380. Belmas', M., operation for the radical cure of hernia, ii. 286. Belloq, M., on the stanching the bleeding from a wounded intercostal artery, i. 492. Benaben's, M., case of excision of part of the hand, iii. 722. Benedict, M., opposed to the radical'cure of umbilical rupture by ligature, ii. 346; mo- dification of the German operation of rhi- noplasty, iiL 590; stimulant treatment of stumps, iii. 648; mode of amputatingthe thigh with a flap from the outside, iii. 660. Bennati, M., on cauterization of the uvula with nitrate of silver in relaxation, i. 166. Bennett, Dr. J. H., on the oscillation at- tending the recovery of the circulation in inflammation,, i. 41; on the process of resolution^ i. 43; on the process of effu- sion, i. 44; on the process of union by adhesion, i. 321 ; on the formation of new vessels, i. 323; on the processes of granulation and cicatrization, i; 325. Bennett's, Mr., case of sarcomatous scro- tum, iii, 549. Bent's, Mr., case of excision of a joint, iii. 726; mode of operating in excision of the head of the humerus, iii. 732. Berard, M., on the removal of the edges of the cleft in staphyloraphy, ii. 32; mode of passing the needle, ii. 33; fatal case from pneumonia, ii. 34 ; on the ligature of the hernial sac for its radical cure, ii. 283; case of femoral rupture, in which the Fallopian tube was protruded, ii. 334; operation for prolapsus uteri, ii. 379; case of fungus of the dura mater treated by operation, iii. 425. Berard's, M., jun., case of invagination of the rectum through the anus, ii. 398. Berdot, M., on dislocation of the head of the thigh-bone downwards and inwards in hip-disease, i. 287 ; case of reduction of the consecutive dislocation in hip-dis- ease, i. 297. Berlichingen's, M. Gotz von, artificial hands, iii. 595. Berlinghieri's, M. Vacca, directions for oesophagotomy, iii. 100; operation for stone, iii. 347. Bernstein's, M-> apparatus for fracture of the neck of the femur, i. 623, Berrens', M., artificial leg, iii. 593. Bertrandi's, M., mode of reducing disloca- tion of the humerus, ii. 225; mode of am- putating at the shoulder-joint with the circular cut, iii. 715. Berzelius', M., opinion relative to the formation of pus, i. 46. Beynard, M.,on the treatment of spina bi- fida by closure of the sac, iii. 190. Bibrach, M., on tying the tonsils, i. 164. Bichat, M., on the vessels of cartilage, i. 252 ; on the changes which the substance of bone undergoes in advanced age, i. 545; on the cause of death from the en- trance of air into a vein, iii. 603. Biesse y's, M., plan of treatment of ingrow- ing of the nail by scraping its free surface till nearly its entire thickness is destroyed, ANALYTICAL INDEX. 787 then touching it with lunar caustic until it contracts completely, i. 223. Biett, M., on the solution of chloride of lime in foul, gangrenous, and torpid ul- cers, ii. 45; on iodine in hard swellings of the testicles, ii. 101. Bigelow's, Dr», employment of ether by inhalation prior to the extraction of a tooth, iii. 768; to the performance of more important surgical operations, iii. 769 ; cases of injurious effects produced by the inhalation of ether, iii. 769. Bile, retention of, iii. 124. Bilguer's, M., objection to amputation, i 381. . Biliary fistula, ii. 151. Billard's, M., case of cure of cerebral rup- ture, ii. 365. Birch's, Mr., case of fatal rupture of the uterus, subsequently to one previously recovered from, ii. 531; case of popliteal aneurism, ii. 494. Bladder, prolapse of, ii. 391; puncturing of, iii. 151; above the pubes, iii. 151; through the rectum, iii. 152 ; through the perineum, iii. 152 ;.stone in, iii. 271. Bladder, Wounds of, i. 527 ; nature and treatment of these wounds, i. 527 ; re- moval Of foreign bodies in wounds of the bladder, as their presence may cause the formation of a calculus, i. 528; South on rupture pr laceration of the bladder in fracture of the pelvis, i. 528; case of grape-shot wound of the pelvis, involving both the rectum and bladder, i. 528; Hennen's case of ball-wound of the pelvis, involving the bladder, i. 528 ; Cline's sen. case of musket-shot wound of the bladder, the ball remaining, and after- wards extracted by operation, i. 529. Blagden's, Mr., case of consecutive he- morrhage after the extraction of a tooth, ii. 141. Blandin's, M., treatment of fracture of the radiusor ujna near the wrist, i. 613; on hydrocele caused by gonorrhoea, iii. 223 ; mode of amputating at the hip-joint with two flaps, iii. 692; at the knee-joint with the flap-cut, iii. 699. Blane, Sir Gilbert, on the period of the accession of tetanus after the receipt of the injury, i. 415 ; case of aneurism of the internal carotid by the side of the sella turcica, ii. 516. Blasius, M., on the nature of. strangula- tion, ii. 269; on the causes of cl ub-foot, ii. 446 ; opposes tenotomy in the treatment of club-foot, ii. 456 ; operation of chilo- plasty, iii. 517; sloping cut in amputa tions, iii, 642; oblique cut in partial am putation of the foot, iii. 705 ; mode of am putating at the shoulder-joint, iii. 716. Blechy, M., on the cause of the difficulty experienced in reducing dislocation of the thumb, ii. 235. Blegny, M., on increased pressure and the supine posture for the radical cure of hernia, ii. 282. Blizard's, Sir W., case of penetrating wound of the chest, i. 483 ; on compres- sion in the treatment of aneurism, ii. 482; case of ligature of the subclavian above the clavicle, ii. 518. Blizard's, Mr. Thomas, case of hydrocele in front of an inguinal rupture, ii. 323 ; case of ligature of the subclavian above the clavicle, ii. 518; on the section of the prostate in the Operation for stone, iii. 320 ; case of simple serous cysts for the neck, iii; 432. Blisters, application of, iii. 619. Block's Mr., experiments on the effects of spurred rye on animals, i. 75. Blood-letting, iii. 608; modes of opera- ting, iii. 608 ; opening veins, phlebotomy, iii. 60S ; situation where performed, iii. 608 ; choice of a vein at the bend of the elbow, iii. 608; mode of opening a vein, iii. 608; South's directions for blood-let- ting from a vein, iii. 609; dressing the wound, and applying the bandage, iii. 610; accidents which occur during the operation, iii. 610 ; faulty stab, iii. 610 ; formation of two small an opening, iii. 610; stoppage of the flow of blood, iii. 610; severe pain from wounding a nerve, iii. 610; wounding an artery, iii. 610; wound of a lymphatic vessel, tendon, or aponeurotic expansion, iii. 610; accidents which may occur after the operation, iii. 610; bleeding, iii. 610; inflammation and suppuration, iii. 610; inflammation of the veins or lymphatics, iii. 610; Abernethy on the treatment of traumatic phlebitis, iii. 611; severe pain and even convulsions from partial divison of a nervous twig, iii. 611; Abernethy on the complete section of the nervous twig in such cases, iii. 611; use of the snapper dangerous, iii. 611; opening the veins of the fore-arm and hand, iii. 611; blood-letting in the foot, iii. 61.1; blood-letting in the neck, iii. 611; direc- tions for opening the external jugular vein, iii. 611; opening arteries, iii. 611 ; only performed on the temporal, iii. 611; mode of operating, iii. 612; South and Cline jun. on arteriotomy, iii. 612;-appli- cation of leeches, iii. 612; mode of apply- ing them, iii. 612; description of the blood-leech, iii. 612 ; of the horse-leech and common leech, iii. 612; means to in- duce leeches to bite, iii. 612; application of leeches to the mouth or near the anus, iii. 613; Crampton and Osborne on the 788 ANALYTICAL INDEX. application of leeches to the mucous sur- faces, iii. 613; treatment after the leeches have dropped off, iii. 613; of the after- bleeding in children, iii. 613; Bricheteau, Lisfranc, Green, and Oliver's cases of fatal haemorrhage from leech-bites, iii. 614; South on the treatment of the after bleeding, 'iii. 615; treatment of ecchy- mosis, inflammation arid suppuration of leech-bites, iii. 615; scarification, iii. 615; • definition and employment of, iii. 615; cupping, iii. 615; mode of operating, iii. 615; dry cupping, iii. 611; South on a substitute for cupping, iii. 616; Dr. Osborne's polytome, iii, 616; South on dangerous haemorrhage from cupping, iii. 616; relative value of leeches and cupping, iii. 616; Junod's apparatus to cause derivation of "blood, iii. 616; South on the relative value of leeches and cup-; ping, iii. 617; South's preference of cup- ping, iii. 617. Blundell, Dr., on prolapse of the womb, ii. 369; on relaxation and incomplete prolapse of the womb, ii. 370; on the size of the prolapsed womb and vagina, ii. 371; on the cause of prolapse, ii. 372; case of removal of the inverted womb by ligature, ii. 368; on the symptoms of pro- lapse of the vagina, ii. 399; on the local symptoms caused by retroversion of the womb, ii. 407; on partial retention of urine in retroversion, ii. 408 ; on the prognosis in retroversion, ii. 411; on an- teversion, ii. 415; case of extirpation of the womb, iii. 570; apparatus for trans- fusion, iii, 628. Boerhaave's, M., opinions relative to the formation of pus, i. 46. Boggie's Staff-surgeon, cases of gun-shot wound, in which a seton was used to bring away separated pieces of bone, i. Boil or furuncle :—character and symp- toms of the disease, i. 150; Walther on the seat of the disease originally in the sebaceous glands of the skin, i. 150; other inflammatory affections of the sebaceous glands, i. 151; Gendrin on the nature of the cores of boils, i. 151; Alibert's-divi- sion of boils into fouTMnds, i. 151; the wasp-nest or malignant boil; i. 151; the pustular boil, i. 152; Dr. Copland's as- thenic boil—furoncle atonique of Guer- saut$ i. 152; description of the disease, its symptoms and progress, U 152; boils often occur in healthy persons without any apparent cause, i. 152; are occasion- ally critical, i. 152; occut after sup- pressed perspiration, from neglect of cleanliness, in persons of irregular habits during menstruation, and in the -spring. i. 153; they appear sometimes to he de- pendent on the state of the atmosphere, and are also met with in the chronic form in dyscratic individuals, i. 153; treatment, i. 153; South's plan of treat- ment by free incision, i. 153; general treatment rarely necessary, i. 153; Rit- ter's idea that boils depend on the reten- tion of the animal refuse, i. 153 ; South recommends the employment of general treatment, i. 153. Boivin, Mad., on anteversion of the womb, ii. 412 ; case of spontaneous reduction of anteversion, ii. .413, Bonafont, M., on the treatment of salivary fistula, ii. 149. Bone, aneurism of the arteries of, ii. 554. Bonfil's, M., operation when the cleft in the soft palate is very large and compli- cated, ii. 34; mode of treating ovarian dropsy, iii. 211; case of spontanous rup- ture of the ovarian cyst, iii. 214; mode of amputating at the shoulder-joint, iii. 716. Bonnet, M., on the chemical and micro- scopic characters of pus, i. 46; on the effects of the resorption of pus, i. 48; ope- ration for the radical cure of hernia, ii. 285; on the application of caustic in varix, ii. 573; on injections of iodine in hydrar- thrus, iii. 1^4; operation for the sub- cutaneous division of the nerve in mental neuralgia, iii. 636 ; on the nature of the uniting medium between the two ends of a divided nerve, iii. 636. Bosch's, M., explanation of wounds from the wind of a ball, i. 374; apparatus for the re-breaking a badly*»nited bone, i. 576. Bossau, M., mortification from spurred Tye noticed, by, i. 75. Bottchek^s, M., apparatus for fracture of the olecranon, i. 614; apparatus for fracture of the neck of the femur, i. 623. Bouillaud, M., on arteritis, i. 89 ; on the redness of the internal membrane of ar- teries, i. 89; on severe phlehitis, i. 93. Boullay, M., on the solution of the chloride of lime in the treatment of foul, gani grenous, or torpid ulcers, ii. 49. Bourgeois', M., observations on malignant pustules,!, 81. Bouvier, M., on the section of the tendo Achillis in club foot, ii. 453. Bowman, Mr. considers there is a difference betwen temporary and articular cartilage, i. 250. Boyer, M., on the lengthening of the limb in hip disease,!. 285; on dislocation into the foramen ovale in hip disease, i. 287; objectsto the^ubdivision of fractures into ANALYTICAL INDEX. 789 complete and incomplete, u 545; infers the impossibility of simple dislocation of • |QSPine' u 5865 case mentioned by him, l. 586; apparatus for fractured clavicle, l. 604; opposed to Astley Cooper's views on the union of fractures of the neck of the femur, i. 620; apparatus for fracture of the neck of the femur, i. 625; on per- manent extension in fracture of the femur, i. 628 ; apparatus for fracture of the pa- tella, i. 633; on rubbing the ends of the broken bones together in cases of false joint, ii. 15; on the treatment of ulcers by sticking plaster, ii. 47; on dressing the wound after the operation for rectal fistula, ii. 167; on the symptoms of anal fissure, ii. 170; on their treatment, ii. 173; operation for the cure of anal fissure, ii. 173; on dislocation of the upper end of the radius forwards, ii. 231; on reduction of dislocation of the astragalus, ii. 253; on the nature of strangulation in rupture, ii. 269; on increased pressure and the su- pine posture for the radical cure of hernia, ii. 282; on cutting away the tunica vagi- nalis, iii. 230; mode of using FrereCome's lithotome, iii. 327; on wens, iii. 450; on the cancerous degeneration of steatoma, iii. 453; mode of amputating by the cir- cular incision, iii. 640. Brachial aneurism, ii 527. ----artery, ligature of, ii. 527. Bradley, Dr., on the blood-fungous, iii. 461. Braid's, Mr., case of re-union of divided parts, iii. 582. Brain, and its membranes, injuries of, i. 436; inflammation of, i. 440; compression of, i. 444; concussion of, i. 449. Bramberger, M., on the effects of torsion, i. 343. Brambilla's, M.,artery-compressor, i. 552. Branching aneurism, ii. 552. Brande's, Mr., analysis of the earthy con- cretions in arteries, i. 91. Brasdor's, M., bandages for fractured cla- vicle, i. 604 ; objected to, i. 603; opera- tion for aneurism, ii. 503; mode of ope- rating in exarticulation of the fore-arm at the elbow, iii. 718. Braun's, M., apparatus for fractures of the leg, i. 637. Breast, Inflammation of; situation and character of, i. 170, causes, i. 170; South on the arrest of the secretion of milk, and its absorption, i. 170; treatment of inflam- mation of the breast, i. 170; abscess of the breast, i. 170; treatment of fistulous openings, i. 171; opening the abscess only advisable when it is very deep, has pro- ceeded slowly, the pain is great, and fever high, i. 171; Langenbeck's treatment of Vol hi.—67 lengthy fistulae* i. 171; the introduction of tents injurious, i. 171; South's recom- mendation that abscess of the breast be opened freely and early, i. 171; advan- tages of the proceeding, i. 172; condem- nation of Langenbeck's plan of treating the fistulae, i. 172; South's treatment Of fistulae, i. 172; milk-knots, i. 172; termi- nations and treatment, i. 172; inflamma- tion of the breast, unconnected with suck- ling, i. 172; causes, i. 173; treatment, i. 173; deep-seated abscesses in the gland, or between it and the pectoral muscles, i. 173 ; to be opened early, i. 173 ; fistu- lous passages to be laid open throughout their whole length, i. 173; Astley Cooper on chronic abscess of the breast, i. 173; South's case of chronic abscess operated on by mistake for scirrhus, i. 173; im- perfection of the nipples, i. 174 ; inflam- mation of the nipple, i. 174; treatment, i. 174; Cooper and Hanney on the treat- ment of fissured nipples, i. 174. Breast, cancer of, iii. 526; chronic inflam- mation of the lymphatics, or of the breast- gland, iii. 530; scrofulous tumours, iii. 530; herpetic and psoric affections, iii. 533; encysted tumours, iii. 533; vesicu- lar scirrhus, iii. 533; hydatid swellings, iii. 534; serocystic tumours, iii. 535; medullary fungus, iii 536; blood swel- lings, iii. 536; hypertrophy, iii. 537. Brefeld's M., apparatus for fractured cla- vicle, i. 603; perferred, i. 605; Brera's, M., plan of treatment preventative of hydrophobia, i. 412. Breschet, M., on the membrane of the fistulous passage, i. 108 ; experiment on the communrcability of hydrophobia from man to man, and from man to beast, i. 403; on the re-union of fractures, i. 548; on the double formation of bony substance in fracture, i. 549 ; on the production of callus, i. 549; on the reduction of old dis- locations, ii. 206; on the causes of con- genital dislocations, ii. 207 ; cases of dis- placement of the heart, ii. 361; on the four principal kinds of true aneurism, ii. 469; on the condition of the artery and vein in aneurismal varix, ii.547 ; on the treatment of aneurismal varix, ii. 549; on spermato- cele, ii. 576; operation for varicocele, ii. 577; directions for its performance, ii. 579; on the nature of corns, iii. 403. Bretonneau's, M., treatment of erysipelas ■ by moderate compression, i. 125; con- demned by Lawrence and Duncan, i. 125; on pressure in the treatment of burns, i. 134 ; on tracheotomy in croup, iii. 115. Bricheteau's, M,, case of fatal haemor- rhage from leech-bites, iii. 614. AL INDEX. 790 ANALYTIC, Briesche's, M., case of softening of the callus, by the internal use of the Carlsbad waters, i. 576. Briggs', Mr., case of recurrence of the aneurism after the ligature of the artery, ii. 499. Brodie, Sir B. C, on sudden loss of blood, a cause of mortification, i. 68 ; case of dry gangrene from inflammation of the principal artery and vein of the limb, i. 72; on the cause of the distinction between dry and moist gangrene, i. 72 ; gangrene from arterial inflammation a compara- tively rare disease, i. 73 ; this statement denied by Cruveilhier and Dupuytren, i. 73; ease of fatal haemorrhage consecutive to opening a tonsillar abscess, i. 162 ; on the rarity of affections of the ligaments independent of other structures, i. 230; on the diseases of the synovial membranes, i. 238; on the two varieties of synovial inflammation, i. 238; case of acute syno- vial inflammation terminating in suppu- ration and ulceration, i. 238 ; on the sub- acute or chronic form of synovial inflam- mation, i. 239; on gonorrhceal rheu- matism and ophthalmia, i. 242; on the pulpy degeneration of the synovial mem- brane, i. 242 ; on the causes and progress of the pulpy degeneration, i. 243 ; on the local treatment of synovial inflammation, i. 245; on the use of friction to promote the absorption of the effused fluid, i. 246; opinion that cartilages are vascular, i. 253 ; on the ulcerative absorption of car- tilage, i. 255; considers that absorption of the cartilages may take place under such circumstances, as to admit of no other agency than that of the vessels of the cartilage, i. 259 ; considers ulceration of cartilages differs from common syno- vial inflammation, and from inflammation of the spongy ends of bones, i. 262; on the degeneration of cartilage into a fibrous structure, i. 263; on the period at which ulceration of the articular cartilages may occur, i. 264; on inflammation of the joint-ends of bones, its symptoms, and progress, i. 264; on the consequences of this inflammation, i. 264 ; on1 the period at which it is likely to occur, i. 266; ob- serves that it is likely to occur in several joints at once, or in succession, i. 266 ; opinion that the occurrence of scrofulous disease in the joints has suspended the progress of some other and perhaps more serious disease elsewhere, i. 266; on the diagnosis between scrofulous disease of the joint-ends of bones and ulceration-of the articular cartilages, i. 267; on the removal of the articular cartilages in old age, as the result of previous ulceration, i. 268; on the symptoms of hysterical affections of the joints, i. 277; on the local applications in such disorders, i. 278; on ulceration of the cartilage, the primary affection in diseased hip-joint, i. .280; on the difference between hip-dis- ease from ulceration of the cartilages, and that from scrofulous deposit in the cancellous structures of the bones, i. 282; explanation of the lengthening of the limb in hip-disease, i. 285 ; on dislocation into the foramen ovale in hip-disease, i. 287; on the influence of the primary irritation of the issue and the maintaining it by re- peated applications of caustic potash, or sulphate of copper, i. 295; approved of by South, i. 295; on the use of a seton in the groin, i. 295; on warm bathing, i. 296; on the importance of rest and posi- tion, i. 296; 'on the treatment of abscesses at the hip, i. 298; recommends free in- cisions in opening these abscesses, i. 299; on the management of abscesses at the hip, i. 299; on the diagnostic symptoms of the diseases of the knee, i. 302; on ulceration of the cartilages of the knee, i. 302; on scrofulous disease in the cancellated struc- ture of the bones of the knee, i. 304; pro- gress of the caries, i. 304; on curvature of the spine from caries, i 308 ; on the occurrence of suppuration in caries of the vertebrae, i. 309 ; on the disappearance of psoas abscess, and its re-appearance else- where, i. 309 ; on the pain in vertebral caries, i. 309; on the extent of the. curva- ture in dorsal caries, i. 309; on the pathology of spinal caries, i. 310; on chronic inflammation of the vertebrae, with ulceration of the inter-vertebral car- tilage, i. 311 ; on the diagnosis between curvature of the spine from caries and that from rickets, i. 312; on the applica- bility of issues in this disease, i. 313; on the manner in which the disease is cured by anchylosis, i. 314; on vertebral caries in the neck, i. 315; on abscess con- nected with vertebral caries in the neck, i. 315 ; on the period of the accession of tetanus after the receipt of the injury, i. 415; on the removal of foreign bodies in injuries of the brain, i. 438; on punc- turing the dura mater when the extra- vasation lies beneath it, i. 447; only employs trepanning in injuries of the head, when secondary symptoms of irri- tation and pressure require it, i. 454; on softeriing of the spinal cord after a severe blow, i. 588; on the attempt to set a fracture through the body of a vertebra, i. 588 ; on the operation for trepanning the spine, i. 589; on fracture of the lower end of the radius, i. 611; on the formation ANALYTICAL INDEX. 791 of a false joint, with a fibro-ligamentous capsule and a lining membrane, ii. 14; on the operation of sawing off the ends of the broken bone, ii. 18; on the impro- priety of operating for fistula in phthisical subjects, ii. 164; on the treatment of large abscesses high up by the side of the rec- tum, ii. 165; on internal erysipelas follow- ing the operation for fistula, ii. 168; on spasmodic contraction of theanus, ii. 171; on spasmodic contraction of the sphincter, attended with ulceration, ii. 171; on the treatment, ii. 172; on incomplete internal urinary fistula, ii. 175 ; on the causes of fistula in perineo, ii 181; on the causes of perineal abscess, ii. 181; on the treatment of fistula in perineo, ii. 183 ; case of ma- lignant disease consecutive on neglected perineal fistula, ii. 183 ; on the treatment of prolapsus ani in children, ii. 401; on the treatment of prolapsed rectum with piles in the adult, ii. 403; case of wry- neck alternating with insanity, ii. 422; on the application of the ligature in te- leangiectasy, ii. 563 ; on the effects of in- flammation on the blood in veins, ii. 588; case of varicose veins of the fore-arm, ii. 569; cases of varicose veins of the arm and chest from compression of the sub- clavian vein, ii. 569 ; on the application of adhesive plasters in the treatment of varix, ii. 770 ; on the subcutaneous divi- sion of the vein in varix, ii. 572 ; on the application of caustic in varix, ii. 572 ; on the removal of internal piles by ligature, iii. 10; cases in which severe symptoms followed the application of the ligature for piles, iii. 11 ; on the application of the ligature for piles, iii. 11 ; on excision of piles, iii. 12; on ulceration of the rectum, in connexion with spasmodic contraction of the sphincter, iii. 41; on the occur- rence of symptoms of strangulated hernia in some cases of stricture, iii. 44; on the post-mortem appearances in stricture of the rectum, iii. 44 ; on the seat of stric- ture in the rectum, iii. 46; on the neces- sity of early treatment in stricture of the rectum, iii. 48; on the distention of the bowel above the stricture by faeces, iii. 48; on the use of bougies, iii. 49; on the internal appliction of mercurial oint- ment in stricture of the rectum, iii. 50; on incision of the stricture, iii. 51; on in- continence of urine in stricture of the urethra, iii. 64; on extravasation of urine from ruptured urethra in stricture, iii. 64; on abscesses communicating with the bladder in old cases of stricture, iii. 64; on the complication of stricture with enlarged prostate, iii. 65; case of enlargement of the urethra from stricture, iii. 65 ; on the formation of cysts of the urethral mucous membrane in stricture, iii. 66; on the oc- currence of rigours and fever in stricture iii. 66; on the existence of an indurated mass at the lower portion of the penis in old strictures, iii. 67; on the original seat of stricture, iii. 67 ; on the use of a full sized bougie in determining the seat of stricture, iii. 70; on the passing a bougie, iii. 70; on the treatment of stricture with bougies, and on their applicability to the various kinds of stricture, iii. 71; direc- tions for the introduction of bougies, iii. 73 ; on the destruction of stricture by ulceration, iii. 78; on the use of thearmed bougie, iii. 79 ; case of apple-core in the rectum, iii.108; case of abscess by the side of the rectum from the irritation of a fo- reign body, iii. 108; case of foreign body in the bronchus, iii. 117; on abscess of the prostate, iii. 137; on catheterism in in- flammation of the prostate, iii. 137 ; on chronic enlargement of the prostate, iii. 138 ; on the characters of enlarged prostate, iii. 141 ; on the rare occurrence of ruptured bladder from retention of urine in enlarged prostate, iii. 141; on the treatment of enlarged prostate, iii. 142; on the treatment of retention of urine from enlarged prostate, and on catheterism in such cases, iii. 142; on effusion of blood into the cellular tissue of the scrotum, iii. 175; on haematocele complicated with dydrocele, iii. 176; case of haematocele in which the tunica vaginalis ruptured, iii. 176; on hydrarthrus, iii. 182; case of hour-glass hydrocele, iii. 221; case of very large hydrocele, iii. 221; on the sponta- neous cure of hydrocele, iii. 223 ; case of relapse of a hydrocele a longtime after the operation, iii. 228; case of foreign body the nucleus of a stone, iii. 249; on the treatment of uric acid gravel, iii. 266; on the connexion between uric acid calculi and gout, iii. 266; on renal calculi of oxalate of lime, iii. 266; on the symptoms of renal calculi, iii. 267; case of renal calculus, iii. 268 ; on the passage of renal calculi into the bladder, iii. 268; cases of renal calculus communicating with ab- scess in the loins, iii. 268; on the treat- ment of renal calculi, iii. 268; on gouty inflammation of the kidneys, iii. 269; on the symptoms of stone in the ureters, iii. 269 ; case of inspection of calculus in the ureter, iii. 270 ; on the prevalence of cal- culi in different classes of society, and at different ages, iii. 271; case of encysted calculus, iii. 274; on the spontaneous breaking up of calculi in the bladder, iii. 274 ; on sounding, iii. 277 ; on the exist- ence of calculous symptoms, without the 792 ANALYTICAL INDEX. presence of a stone in the bladder, iii. 277; on the use of stone solvents, iii. 281; on the dilatation of the urethra, iii. 283; on the dilatation of the female urethra, iii. 283; case of enoysted calculus removed by the lateral operation, iii. 310; on the external incision in lithotomy, iii. 311; on the section of the prostate and bladder, iii. 318; on contraction of the bladder during lithotomy, iii. 331; on the effects of he- morrhage in lithotomy, iii. 334 ; case of fatal venous hemorrhage in lithotomy,iii. 334 ; case of secondary hemorrhage after lithotomy, iii. 335; on the dangerous symptoms which follow the incision of the prostate extending into the loose cellular texture surrounding the neck of the blad- der, iii. 341; on thereoto-vesical operation, iii. 344; on the expulsion of small calculi from the bladder in women, iii. 349 ; case of ulceration of the bladder and vagina from the pressure of a large calculus, iii. 349 ; modification of the vertical cut up- wards, iii. 350; on the incontinence of urine consequenton lithotomy in women, iii. 353; on the occurrence of hemorrhage and of rigors after lithotrity, iii. 359 ; on the cases in which lithotrity should be performed, and on those in which litho- tomy should be preferred, iii. 360; on the nature of corns, iii. 403 ; on lipoma dif- fusum, iii. 426 ; case of fatty tumour con- nected with the spermatic cord within the abdominal ring, iii. 428; on inflammation of fatty tumours running on to abscess, iii. 429; opinion that fatty tumours sometimes take on a malignant degeneration, iii. 429; case of fatty tumour partially removed by liq. potassae, iii. 429; on simple cysts in the femaw breast, iii. 432 ; case of long- standing scirrhus, iii. 509; on scirrhus of the breast, iii. 527; on scirrhus of the nipple, iii. 529; on the puckering in of the skin in mammary cancer, and on its cause, iii. 529; on sero-cystic tumors of the female breast, iii. 535; on'the question as to the propriety of removing a scirrhous breast, iii. 539; on the circumstances per- mitting the operation, iii. 539. Bromfield, Mr., on incisions and injections of bark and tincture of myrrh in carbun- cle, i. 157 ; invention of the tenaculum, i. 355; case of necrosis from irritation, ii. 121; operation for stone in the bladder, iii. 317; on amputation just above the ankle, iii. 674. Bronchocele, iii. 385; definition and cha- racters, iii. 385; symptoms when the bron- chocele is large, iii. 385; varieties, iii. 385; symptoms and treatment of inflammation of the thyroid gland, iii. 386 ; vascular or\ aneurismatic bronchocele, iii. 386 ; charac- ters, iii. 386; lymphatic bronchocele, iii. I 386; characters,iii.387; seat of the disease, iii. 387; South on lymphatic bronchocele and serous cysts in the neck, iii. 387; scirrhous bronchocele, iii. 388; characters, iii. 388; causes of bronchocele, iii. 388; M'Clellan on the cause of bronchocele, iii. 388; Inglis and Copland on the age at which bronchocele is most usual, iii. 389; Dr. Robertson and M'Clellan on bron- chocele as a variety of scrofula, iii. 389; prognosis, iii. 389; treatment, iii. 390; in vascular bronchocele, iii. 390; ligature of the superior thyroideal artery, iii. 390 ; mode of operating, iii. 391; after-treat- ment, iii. 392 ; relative value of this ope- ration, and other modes of treatment formerly recommended, iii. 392 ; the tu- mour may increase in size after this ope- ration from the enlargement of the inferior thyroid, and its communicating with the superior, iii. 392; Coates and Wickham's case in which the bronchocele ultimately enlarged, after the ligature of the superior thyroid, iii. 392; ligature of the inferior thyroid artery, ii'. 392; treatment of lymphatic bronchocele, iii. 392 ; exhibi- tion of burnt sponge and iodine, iii. 392; dangerous symptoms caused by large doses of iodine, and their treatment, iii. 394; contra-indications to the use of iodine, iii. 394; Graefe's treatment of bronchocele, iii. 394 ; Inglis' objections to Coindet's mode of exhibiting iodine, iii. 395; Dr. Gairdner on the dangerous symptoms occasionally caused by iodine, iii. 395 ; South on the exhibition of iodide of potassium, iii. 395 ; external remedies for bronchooele, iii. 395; South on the employment of iodide of potassium in the form of ointment, iii. 396; ligature of the superior thyroid artery in lymphatic bronchocele, when it presents a cartila- ginous hardness, iii. 396; employment of the seton, iii. 396; mode of applying it, iii. 396; fatal results have occasionally followed its use, iii. 397 ; incision of the bronchocele, iii. 397; puncturing the bronchocele, iii. 397; Maunoir's treatment by puncture, and irritating injections, and by seton, iii. 397 ; extirpation very dan- gerous, and to be almost entirely for- bidden, iii. 398; cases in which extirpa- tion is admissible, and mode of operating, iii. 398; Green's case, iii. 398; Mayor and Bach's extirpation of bronchocele by liga- ture, iii. 398; Regal de Gaillac's extirpa- tion of bronchocele by subcutaneous liga- ture, iii. 398. Brown's, Dr., case of a piece of broken delf plate in the oesophagus, iii. 98. Brown's, Mr., treatment of ovarian dropsy,' iii. 210. Brown, Mr., removal of the acromion and ANALYTICAL INDEX- 793 glenoid cavity in amputation of the shoul- der-joint, iii. 717. Bruckner, M., on the causes of club-foot, ii. 446. Brugman's, M., opinions relative to the formation of pus, i. 52. Briinninghausen's, M., straps for fractured clavicle, i. 603; objected to, i. 603; ap- paratus for fracture of the neck of the femur, i. 624; on permanent extension in fracture of the femur, i. 628; on the spontaneous cure of umbilical rupture, ii. 346 ; artificial leg, iii. 593 ; recommenda- tion to swathe a limb in flannel, prior to amputation, to diminish the loss of bjood, iii. 638; mode of amputating by the cir- cular incision, iii. 640 ; management of the periosteum, iii. 642. Bryce's, Dr., mode of amputating at the hip-joint with the flap-cut with a single flap, iii. 691. Buchanan's, Mr., operation of puncturing the abdomen through the bladder for dropsy, iii. 208. Bucking's, M., apparatus for fracture of the patella, i. 633. Bujalsky, M., on ligature of the innomi- nata, ii. 522; operation for tying the internal iliac, ii. 534; on the ligature of the, external iliac, ii 538 ; case of exci- sion of a portion of the accessory nerves of Willis, iii. 636. Bulley, Mr., on simultaneous dislocation of the radius forwards and of the ulna backwards, ii. 232. Bullock's, Mr., case of a quartz pebble in the upper part of the larynx, iii. 111. Burchard's, Mr., obturator for vesico-va- ginal fistula, ii. 189. Burder, Mr., on erethismus mercurialis, ii. 109. Burns, Mr. Allan, on the spontaneous bursting of a tonsilar abscess, i. 161 ; attended with much danger, i. 161 ; de- tails of a case in which the trachea was deluged with purulent matter, and death by suffocation ensued, i. 161; advice in such cases to tap the abscess with trocar and canula, i. 162; directions for opening a tonsillar abscess, i. 162; case of fatal hemorrhage consecutive to opening the abscess, i. 162 ; on, the formation, of cal- culi in the tonsils, i. 162; on the fre- quency of congenital rupture in the fe- male, ii. 328; on carotid aneurism,ii..507; proposal to tie the innominata, ii. 521 ; on the difference between.fungus hema- todes and sarcoma medullare, iii. 460; on extirpation of the parotid, iii. 524. Burns, Mr. John, on the treatment of scro- fulous ulcers, ii. 53 ; on prolapse of the vagina, ii. 389; on the anteversion of the womb, ii. 412. Burns :—causes of burns, i. 126; different degrees of burns, i. 126; Dupuytren's subdivision of burns, i. 126 ; first degree of burn, a bright uncircumscribed redness of the skin, i. 126 ; second degree, vesi- cation, i. 126 ; third, more intense burn, with destruction of the cuticle and rete mucosum, i. 126 ; fourth, gangrenous de- struction of the parts, i. 126; symptoms of each degree of burn, i. 126, 127; South on burns, i. 127; burns generally more dangerous than scalds, i. 127 ; complete immersion of a person in boiling water fatal in ten or fifteen minutes, i. 128; persons whose entire surface has been charred by fire may live for several hours, i. 128:; the danger of burns and scalds is the greater in reference to the part in- jured, i. 128 ; treatment of the slightest degrees of burns, i. 128; treatment of parts deprived of the cuticle, i. 128; after suppuration is established, i. 128; when mortification is caused by the burn, i. 129; various remedies for burns, i. 129; Fricke's solution of lunar caustic, i. 129; Larrey's plan of treatment, i. 129 ; Lis- franc's employment of the solution of the chlorate of lime, i. 129 ; Earle on cold moistapplications, i. 129; Hunter on cold, i. 129; Kentish's plan of treatment, i. 130 ; mode of application as stimulants, i. 13ft; disapproval of frequent dressings, i. 131 ; application of raw cofcton.,i. 13:1; Gibson, Dallam, and Anderson on raw cotton, i. 131; only applicable in snper- ficial burns, i. 131; employed by Ander- son in recent and old burns, vesicated and sphacelated, i. 132; preparation of the cotton, i. 132; application of flour, i. 132; Dr. Ward on the application of flour, i. 132; mode of application, i. 132; Ward's objection to liquid applications, i. 132 ; modus operandi of the flour, i. 133; Mar- shall on the application of the flour, i. 133; South on the use of flour, i. 133; Hunter on, the primary treatment of burns, i. 133; Bretonneau and Velpeau on pressure in the treatment of burns, i. 13.4; Velpeau considers compression best adapted to cases of burn in the third and fourth degrees, but also applicable in those of the second degree, i. 135; mode of appli- cation of compression, i. 135; advantages of this plan of treatment according to Velpeau, i. 135; Earle on the removal of the clothes after burns and scalds, i. 135; South on the treatment of burns and scalds, i. 135; Higginbotham's treatment by the nitrate of silver, i. 136; immediate amputation inadmissible, even when an 67 794 ANALYTICAL INDEX. entire limb has perished; the line of de- marcation must be first formed, i. 136; when the destruction of skin on a limb has been very extensive, leaving large wounds without a disposition to heal, and exhausting the strength by the extent of suppuration, amputation should be per- formed, i. 137; burns from gunpowder, i. 137; the grains of powder to be picked out of the face with a lancet or needle, i. 137; employment of internal remedies, i. 137 ; the antiphlogistic treatment re- quisite if the inflammation be high, i. 137; opium required to relieve the pain, i. 137; South on the internal treatment of burns and scalds, i. 137; the occur- rence of rigors to be met with stimulants, and external warmth, i. 137 ; exhibition of opium, i. 187; objections to its use, i. 137; protracted sickness and vomiting an unfavourable sign, i. 138; treatment of febrile excitement, i. 138; support to be given during suppuration, or the se- paration of sloughs, i. 138; great care required during the process of cicatriza- tion, i. 138; tendency of the cicatrix to contract, i. 138; Earle on the contraction of the cicatrices, i. 138; the contraction the result 6f a natural process, i. 138; Hunter on the contraction of the granula- tions during cicatrization,!. 138; South on the effects of this contraction, i. 139; Earle on the effects of the contraction, i, 139; division of the contracted cicatrix followed by the reproduction of the con- traction when the wound had healed, i, 139; the same effect followed the removal of the webbed portion of the scar, i. 139; Earle's operation for the removal of the entire cicatrix, i. 139; Earle's case in which this operation was performed, i. 139; case by South, i. 14C; Mutter's plastic operations for the relief of defor- mities from burns, i, 142 ; occurrence of abdominal disorder and diarrhoea during the cicatrization of extensive burns, i, 143. Bursae mucosae, dropsy of, iii. 178, Bush's, Mr., apparatus for fracture of the lower jaw, i. 580. ^ Bushe, Dr., describes two forms of pro?; lapsed rectum, ii. 398; on the characters of prolapse of the rectum, ii. 395); on the diagnosis between prolapsed rectum and haemorrhoids and intusrsusception ii 399; on the changes in the mucous mem- brane of the rectum in old prolapses, ii. 400; on relaxation of the anus, ii. 405; on relaxation of the rectum with invagi- nation of the mucous membrane, ii. 405; on the local symptoms of piles, ii. 582; on the effeets of loss of blood from piles. ii. 582; on the removal of internal piles by ligature, ii. 583 ; on the treatment of haemorrhage after the removal of piles, ii. 585; on spasmodic contraction of the anus, iii. 41; on stricture of the rectum, iii. 46; on the seat of the stricture, iii. 47. Butt's, Dr., case of excision of the lower part of the ulna on account of necrosis, iii. 735. Cachexia syphiloidea ormercurialis, i. 110. Caesarean operation, iii.< 155. Calculus, urinary: Magendie, von Wal- ther, Austin, Wetzler, Willis, and Jones, on the formation of calculi, iii. 237 ; ge- neral constituents of calculi, iii. 241; other and more rare constituents, iii. 241; Tay- lor on the rarity of carbonate of lime cal- culi, iii. 242; uric acid and uriate of am- monia, iii. 242 ; the combination of, uric acid with ammonia, and its precipitation in the free state on the cooling of the urine, iii. 244; the development of free acids in the urine, iii. 244; oxalate of lime, iii. 244; frequently forms the nucleus of a calcu- lus but not uncombined, iii. 244; a cal- culus of almost pure oxalate of lime has been met with, iii. 244; Prout and Walther on the origin of oxalic acid in the urine, iii. 244; presence of free oxalic acid in the urine, iii. 244; combinations of oxalic acid, iii. 245; cystin, iii. 245; calculi of cystic oxide rare, iii. 245; usually consist entirely of this substance, but occasionally met with as nuclei of other calculi, iii. 245; formation of cystic calculi, iii. 245; chemical composition, iii. 246; xan- thic oxide, uric oxide, iii. 246; of very rare occurrence,iii.246;chemical composition, iii. 246; never occurs in solution, or as a precipitate from the urine, iii. 246; phos- phate of ammonia and magnesia, iii. 246; causes of its formation, iii. 246; Jones on the phosphatic diathesis, iii. 247; con- necting material of calculi, iii.247; causes of the production of gravel and calculi, iii. 247; remote causes, iii. 247; Taylor on the calculi of children, ii. 248; foreign bodies in the bladder act as the nuclei of calculi, iii. 24-; foreign bodies rarely coated with uric aoid, iii. 246; South on foreign bodies as the nuclei of stones, iii. 218; Astley Cooper, Brodie, and Everard Home's cases, iii, 249; A. White and Ar- not?s oases of foreign bodies in the va- gina, the bladder injured, and formation of calculi, iii. 249; varieties of calculi, iii. 250; characters, iii. 250; characters of uric acid calculi, iii. 250; of uriate of am- monia, iii. 250 ; of mulberry stones, iii. 250; of hempseed calculi, iii. 250; of the ANALYTICAL INDEX. 795 earthy phosphates, iii. 250; of the phos- phate of lime, iii.250; of the fusible stone, ui. 250 ; of the eystic oxide, iii. 250 ; of xanthic oxide, iii. 251 ; of carbonate of lime, iii. 251; physical characters of cal- culi, iii. 251; division of calculi according to their chemical composition, iii. 252 ; frequency of the different kinds of cal- culi, iii. 252 ; amorphous urinary sedi- ments, iii. 253; Dr. Prout on lithic or uric acid sediments, iii. 253; characters of yel- low sediments, iii. 253; of red or lateri- tious sediments, iii. 253; of pink sedi- ments, iii. 253; white lithate or urate of soda sediment, iii. 254; characters and accompanying symptoms of the phos- phatic sediments, iii. 254 ; causes of the phosphatic sediments, iii. 255; oxalate of lime sediment, iii. 255; characters of the urine in cystic oxide calculus, iii. 255; gravel, iii. 256; definition and cha- racters, iii.256; Magendie on hairy gravel, iii. 256; symptoms of gravel, iii. 256; Prout on the characters and symptoms of crystallized uric acid gravel, iii. 256; Prout on the crystallized phosphatic se- diments, iii. 256; Prout on the rarity of crystallized oxalate of lime gravel, iii. 257; symptoms of the oxalate diathesis, iii. 258; causes and treatment, iii. 258; treatment of gravel, iii. 258 ; of uric acid gravel, iii. 258 ; Wetzlar, Jones, Wil- son Philip, and Brodie on the treatment of uric acid gravel, iii. 259; Prout on the treatment of a fit of the gravel, iii. 260; Jones on the treatment of uric acid gravel; iii. 260; treatment of cystio oxide gravel, 261; of oxalate of lime gravel, iii. 261; of phosphate of lime gravel, iii. 262; Prout on the treatment of cystic oxide gravel, iii. 262; Prout and Jones on the treatment of the oxalate of lime diathesis, iii,a62 ; Prout and Jones on the treatment of the phosphatic dia- thesis, iii. 263; stones in the kidneys, iii. 265; situation, iii. 265; Prout on the formation of uric acid calculi in the kid- neys, iii. 265; Brodie on the oonnexion between uric acid calculi and gout, iii. 266 ; Prout and Brodie on renal calculi of oxalate of lime, iii. 266; Prout on renal calculi of cystic oxide, iii. 267; Prout on the rarity of phosphatic renal caleuli, iii. 267 ; diagnosis, iii. 267 ; symptoms, iii. 267; Brodie on the symptoms of renal calculi, iii. 267; Astley Cooper and Bro- die's cases, iii. 267 ; progress of stone in the kidney, iii. 267; Brodie on the pas- sage of renal calculi into the bladder, iii. 267; Hevin, Astley Cooper and Brodie's cases of renal calculi communicating with abscess in the loins, iii. 268; Crisp's case of fracture of a renal calculus by sudden exertion, iii. 268; treatment, iii. 268 ; re- moval of the calculus by nephrotomy, iii. 268 ; directions for the operation, iii. 268; Brodie and South on the treatment of renal calculi, iii. 268; Prout on the treat- ment of nephritis complicating renal cal- culi, iii. 268; Brodie on gouty inflamma- tion of the kidneys, iii. 269 ; stone in the ureters, iii. 269; symptoms, iii. 269; treat- ment, iii. 269; Brodie on the symptoms of stone in the ureter, iii. 269 ; Brodie and Travers' cases of impaction of calculi in the ureters, iii. 270; Cline and Astley Cooper's cases of suppuration of the kid- ney from impaction of calculi in the ure- ters, iii. 270; Astley Cooper on the treat- ment of calculi in the ureters, iii. 270; stone in the bladder, iii. 271} origin and varieties, iii. 271 ; Brodie on the preva- lence of calculi in different classes of so- ciety, and at different ages,iii. 271; Smith on the statistics of lithotomy, iii. 271; Copland Hutchinson on the rarity cal- culus among seamen, iii. 271; forms of calculi in the bladder, iii. 272; characters and situation, iii. 272; sacculated and ad- herent oalculi, iii. 272 ; Taylor on hour- glass calculi, iii. 273; Cline, Mayo,Astley Cooper, Smith and Cheselden's oases of large calculi, iii. 273 ; Martineau's cases of very small stones, iii. 273; Astley Cooper's ease of a great number of calculi in the bladder, iii. 273; Pott's case of fu- sible calculus in a vesical rupture,iii. 273; Brodie's case of encysted calculus,iii,274; Wickham's case of caloulus enclosed ina hag of lymph inorusted with oaloulous matter, iii. 274; Brodie, Proutand Crosse on the spontaneous breaking up of cal- culi in the bladder, iii. 275; symptoms of vesical calculus, iii. 275; Prout on the symptoms of vesical calculus, iii, 275; sounding the bladder, iii. 277; Klein, Brodie, and South on sounding, iii. 277; Brodie and South on the existence of cal- culous symptoms, without the presence of a stone in the bladder, iii. 277 ; South on the simulation of caloulus by vesical polypus, iii. 277; measuring the size of the calculus, iii. 278 ; South on measuring the calculus, iii. 278; various modes of treatment, iii. 278 ; internal use of stone- solvents, iii. 279 ; empirical remedies, iii. 279; efficacy of stone-solvents, iii. 279; Liston's case of partial sol ution of a stone in the bladder, iii.-280; injection of sol- vents into the bladder, iii. 280; directions for the use of solvent injections, iii. 280; difference of opinion as to the value of these modes of treatment, iii. 980; Pe- louze's experiments, iii. 281; Prout and 796 ANALYTICAL INDEX. Brodie on the use of stone-solvents, iii. 281; dissolving stone by means of the galvanic pile, iii. 282; the apparatus and its application, iii. 282; extraction of the stone through the urethra, iii. 283; by di- latation, iii. 283; principally applicable to females, iii. 283; mode of effecting the dilatation, iii. 283; Brodie on the dila- tation of the urethra, iii. 283; Astley Cooper, Liston and Brodie on the dila- tation of the female urethra, iii. 283; crushing the stone,—lithotrity, iii. 2W5; Gruithuisen, Eiderton, and Sanctorius' lithotritie instruments, iii. 285; case of the Monk of Citeaux, iii. 286; General Martin's case, iii. 286; improvement of lithotritie instruments, iii. 286; three classes of lithotritie instruments, iii. 287; relative value of these instruments, iii. 287; advantages and disadvantages of the three-limbed perforating forceps, iii. 288; of Jacobson's instrument, iii. 288; of Heurteloup's percuteur, iii. 288; treat- ment prior to the operation, iii. 288 ; posi- tion of the patient, iii. 289; mode of ope- rating, iii. 289 ; with the three-limbed perforating forceps of Civiale and Leroy, iii. 289; with Jacobson's instrument, iii. 289; with Heurteloup's percuteur, iii. 291; duration of a lithotripti© sitting, iii. 292; treatment after the operation, iii. 292 ; escape of sand and calculous fragments, iii. 292; arrest of fragments in the ure- thra, iii. 293; breaking up the fragments in the bladder, iii. 293 ; treatment of frag- ments of calculus fixed in the urethra, iii. 293 ; by extraction, iii. 293 ; removal by incision, iii. 294; examination of the bladder when the calculous symptoms have ceased,iii. 294; lithotrity in women, iii. 294 ; cuttpigfor the stone,—lithotomy, iii.' 296 j definition, iii, 297; should be performed early, iii. 297 ; circumstances contra-indicating, the operation, iii. 297; Cline,. Attenburrow and ^ Astley Cooper's cases of old men operated on for stone, iii. 297; Keate, Hunter and Civiale's ope- rations on infants, iii. 2.97; Green's case of lithotomy in a fat man of 50 years of age, iii. 298; preparation of the patient for the operation, iii. 298; cutting for the stone in man, iii. 298 ; with the little or Celsian apparatus, iii. 299; mode of operating, iii. 299 ; objections to the operation, iii. 299 ; cutting for the stone with the great appa- ratus, iii. 299; mode of operating, iii 299 ; advantages of this operation over the little apparatus, iii. 300; the high operation, iii. 301; mode of operating, iii. 302; modi- fications of the operation, iii. 303 ; dress- ing the wound, iii. 304; the prevention of infiltration of urine from this operation, iii. 305; treatment of the wound for some days, iii. 305 ; untoward circumstances during and after the operation, iii. 305; advantages and disadvantages of the ope- ration, and cases in which it is applicable, iii. 305; Cheselden on the high operation, iii. 306; the lateral operation, iii. 307; Rau's mode of operating, iii. 307; Chesel- den's operation for stone, iii. 309; pre- parations for the operation, iii. 309; South on the binding a patient prior to the ope- ration, iii. 310; mode of operating, iii. 310 ; Brodie's case of encysted calculus removed by the lateral operation, iii. 310; South's case of stone undetected by the sound during eight years, iii. 310; Brodie and South on the external incision, iii. 311 ; Scarpa on the division of the pros- tate, iii. 312; Key and Liston's modes of operating for stone, iii. 313, 314 ; Dr. James Douglas and Sharp on Cheselden's operation, iii. 314; Douglas on the dis- section of the parts concerned in this ope- ration, iii. 315; "Martineau and Brom- field's operations, iii. 317; Brodie on the section of the prostate and bladder, iii. 318 ; use of Langenbeck's knife, iii. 319; Thomas Blizard, Astley Cooper,and Tyr- rell on the section of the prostate, iii. 320; extraction of the calculus, iii. 320; use of the cutting gorget, an improvement on Cheselden's bluntgorget, iii. 321; Cline's gorget, iii. 321; Scarpa's gorget,.iii. 321; Astley Cooper on opening the membran- ous part of the urethra, iii. 321 ; South on the use of the cutting gorget, iii. 321; ob- jections to the cutting gorgets, iii. 324; South's opinion that these objections are groundless, iii. 324 ; Le Cat and Pajola's mode of operating for stone, iii. 324; ob- jections to the operation, iii, 325; Frere Come's operation with the lithotome cache, iii. 326 ; disadvantages of the instrument, iii. 326; Boyer's mode of using Frere Come's lithotome,?iii. 327; Dupuytren's bilateral section, iii. 327 ; mode of operat- ing, iii. 327; Beclard's modification of the operation, iii. 327; advantages and disad- vantages of the operation, iii. 328; extent of the incision in the prostate and neck of the bladder, iii. 329 ; extraction of the stone, iii. 329 ; obstacles to the extraction of the stone, iii. 330 ; taille on deux terns, iii. 330 ; Brodie and South on contraction of the bladder during lithotomy, iii. 331; extraction of the stone when enclosed by a contracted bladder, iii. 331; of an en- cysted stone, iii. 332 ; of a stone lodg- ing in the,ureter, and projecting into the bladder, iii. 332; of a stone lying in a hollow, iii. 332 ; of a stone covered with fungosities, iii. 332; of a brittle and easily ANALYTICAL INDEX. 797 breaking stone, iii. 332 ; dressing the wound, iii. 332; haemorrhage during the operation, iii. 333 ; from the branches of the superficial perineal artery, iii. 333 ; from the inferior haemorrhoidal, iii. 333 ; from the internal haemorrhoidal, iii. 333; from the internal pudic, iii. 333; from the vesical, iii. 333; treatment of the haemorrhage, iii. 333 ; Erard, Dupuytren, and von Graefe's compressors, iii. 333; Shaw's case of fatal haemorrhage in litho- tomy, from wound of the dorsal artery of the penis, iii. 334; Brodie on the effeots of haemorrhage in lithotomy, iii. 334 ; South on the treatment of haemorrhage during and after the operation, iii. 334; Brodie's case of fatal venous haemorrhage in litho- tomy, iii. 334; symptoms of haemorrhage into the bladder after the operation, iii. 334; South on secondary haemorrhage after lithotomy, iii. 335; Brodie, Earle, Travers, Green, and South's cases, iii. 336; wounding the rectum, iii. 336; South on wounding the rectum, iii. 337 ; con- vulsions and fainting, iii. 337 ; after-treat- ment, iii. 338 ; South on the treatment to be adopted after the operation for litho- tomy, iii. 338; causes and treatment of inflammation after the operation, iii. 340 ; of spasm, iii. 340; Key on suppurative in- flammation of the cellular tissue sur- rounding the bladder the most frequent cause of death after lithotomy, iii. 340 ; Brodie on the dangerous symptoms which follow the incision of the prostate exten- ding into the loose cellular texture sur- rounding the neck of the bladder, iii. 341; treatment of the conseoutive haemorrhage, iii. 342 ; abscesses about the neck of the bladder, iii. 342; incontinence of urine and impotence, iii. 342; disposition to lithogenesis, iii. 342; opening the bladder from the perinaeum, iii. 343; Foubert's operation, iii. 343; cutting for the stone through the rectum, iii. 343 ; Brodie on the recto-vesical operation, iii. 344 ; Sol- ly's case of recto-vesical operation, iii. 344; Sanson's two modes of operating, iii. 344; description of the operation, iii. 344; modifications of the operation, iii. 345; after treatment, iii. 345 ; advantages and disadvantages of the recto-vesical opera- tion, iii. 346 ; results of recto-vesical li- thotomy, iii. 346; Vacca Berlinghieri and Dupuytren's operations for stone, iii. 347; cutting for the stone in women, iii. 348 ; various modes of operating, iii. 348; Ast- ley Cooper on the symptoms of stone in women, iii. 348; Brodie on the expulsion of small calculi from the bladder in wo- men, iii. 349; Brodie and Astley Cooper's cases of ulceration of the bladder and va- gina by the pressure of large calculi, iii. 349 ; cutting for the stone in women by the lateral operation, iii. 349 ; mode of operating, iii. 349; the horizontal cut on one or both sides, iii. 349; Liston's ope- ration, iii. 350; the vertical cut upwards, iii. 350 ; Brodie's modification of the ver- tical cut upwards, iii. 350; advantages of the vertical cut upwards, iii. 351; the vertical cut downwards, iii. 351; the cut below the pubic symphysis, iii. 351; ob- jections to the operation, iii. 351; Lis- franc's vestibular cut, iii. 351; mode of operating, iii. 352 ; objections to the ope- ration, iii. 352; von Kern's operation, iii. 352 ; the vagino-vesical cut, iii. 353 ; ad- vantages of this operation, iii. 353; Astley Cooper, Brodie, Liston, Hey, and South on the incontinence of urine consequent on the operation, iii. 353 ; South on dila- tation of the female urethra for the extrac- tion of calculi, iii. 354; opening the blad- der above the pubic symphysis, iii. 354 ; comparison of lithotomy and lithotrity, iii. 354 ; equality of the possible evils after the two operations, iii. 354; possible evils from lithotrity, iii. 355; Liston on the breaking or bending of lithotritie instru- ments in the bladder, iii. 356 ; Brodie on the occurrence of haemorrhage and of rigors after lithotrity, iii. 356; comparison of the results in lithotomy and lithotrity, iii. 356 ; cases in which lithotrity is inap- plicable, iii. 357; lithotomy preferable for children, iii. 357 ; lithotrity preferable in advanced age, females, and in very stout persons, iii. 357 ; stones of moderate size, and round or oval in 6hape, best for crushing, iii. 357; cases in which litho- trity is preferable, and cases in which lithotomy should be performed, iii. 357 ; stricture of the urethra only a temporary contra-indication to lithotrity, iii. 357; palsy of the bladder not a contra-indica- tion, iii. 357; Key on the advantages and applicability of lithotrity, iii. 357; Key on lithotrity with reference to the size of the calculus, iii. 3")8; Key on the applica- bility of lithotrity or lithotomy according to the age of the calculous patient, iii. 358 ; Key on the requisite condition of the bladder for the operation of lithotrity, iii. 358; Key on irritability of the bladder, iii, 35-'; Brodie,Liston,andSouth on the cases in which lithotrity should be performed, and on those in which lithotomy should be preferred, iii. 360; stone in the urethra, iii. 363 ; consequences of the impaction of stones or other foreign bodies in any part of the urethra, iii. 362 ; Travers' case of calculus in the urethra, iii. 362; Home's case of retention of urine, and consequent 798 ANALYTICAL INDEX. mortification from the impaction of cal- culi in the urethra, iii. 362; Liston's case of a small brass ring encircling the penis, iii. 363; symptoms of stone at the neck of the bladder, iii. 363 ; treatment and re- moval by operation, iii. 363; South on the treatment of stone in the urethra, iii. 364; symptoms and treatment of stone in the membranous part of the urethra, iii. 364; of stone in the spongy part of the urethra, iii. 364; in the fossa navicularis, iii. 364; the entire urethra, in rare cases, blocked up with calculi, iii. 364; South on the ex- traction of calculi in the urethra in front of the scrotum without. incising the canal, iii. 364 ; urinary calculi external to the urinary passage, iii. 365 ; are met with in the perinaeum or scrotum from the de- struction of the walls of the urethra, iii. 365 ; consequences, iii. 365 ; may also oc- cur in the vagina or rectum by the de- struction of their parietes, iii. 365 ; Vin- cent's case of calculi in the perinaeum, iii. 365 ; Vincent's case of calculi between the prepuce and glans penis, iii. 366; treatment of these calculi, iii. 366; pros- tatal stones, iii. 366; varieties, iii. 366; Astley Cooper's case, iii. 367; treatment by operation, iii. 368; Green's case of encysted stone, iii. 368; Travers' case of stone broken up under the use of con- stitutional stone solvent, iii. 368; statistics of the operations of lithotomy at St. Tho- mas' hospital from 1800 to 1846, iii. 368 ; lithectasy, cystectasy, iii. 375 ; object of the operation, iii. 375 ; originally proposed by John Douglas, iii. 375 ; Dr. Arnott and Astley Cooper's case, iii. 376; Elliot, Dr. Wright, and Fergusson's cases, iii. 376. Callaway, Mr., on the haemorrhage follow- ing the extirpation of the tonsils, i. 166 ; case of retention of a ligature on an artery for four months, i. 340 ; case of reduction en masse, ii. 274; case of removal of de- generated omentum, ii. 300 ; on the seat of femoral rupture, ii. 333. Callisen, M., on the removal of the entire skin covering a cold abscess, i. 105 ; ex- planation of the lengthening of the limb in hipfldisease, i. 285 ; on the reduction of the consecutive dislocation, i. 297; on the premonitory pains of hydrophobia, i. 408 ; mode of operating for the formation of an artificial anus at the lower end of the colon, iii. 37. Callosities, iii. 400. Camper's, M., explanation of the lengthen- ing of the limb in hip-disease, i. 285 ; on the causes of club-foot, ii. 446. Camus', Mr., mode of treating ovarian dropsy, i. 488; case of spontaneous rup- ture of the ovarian cyst, iii. 214. !ANCER,iii. 496; definition, iii. 496; origin, iii. 496; symptoms of scirrhus, iii. 496; progress of the disease, iii. 496; concealed cancer, iii. 496; ulcerated cancer, iii. 496; condition of the parts in scirrhus, iii. 497; in concealed cancer, iii. 497; microscopic elements of scirrhus, iii. 497 ; Muller on the four several kinds of carcinoma, iii. 497 ; Muller on carcinoma simplex and fibrosum, iii. 498; Muller on carcinoma reticulare, iii. 498 ; Muller on carcinoma alveolare, iii. 498 ; Muller on carcinoma fasiculatum, iii. 498 ; Dr. Hodgkin on the development and progress of scirrhus, iii. 499 ; secondary development of cancerous ulceration, iii. 500; seat of cancer, iii. 501; difference in the progress of cancer in different persons, iii. 501 ; Alibert on the varieties of cancer, iii. 502 ; diagnosis of scirrhous tumours, iii. 502 ; Scarpa on the diagnosis between scrofula and scirrhus, iii.503; Hodgkin on the diagnosisbetween scirrhus and medullary fungus, iii. 503; Foy's analysis of scirrhus, iii. 504; cancer in the skin, 504 ; origin and seat, iii. 504 ; symptoms, iii. 504 ; occurrence of ulcera- tion, iii. 505 ; origin of cancer in glands, iii. 505; characters of cancer in mucous membranes, iii. 505 ; cancer in the bones, iii. 505; characters of cancer in the nerves, iii. 505; other tumours in nerves, and their treatment iii.506;Cheselden'scases, iii. 506; Astley Cooper's case of tumour in the popliteal nerve, iii. 506 ; Liston on tu- mours of nerves, iii. 506;Langstaff,South, Astley Cooper, Cline, and Mayo on tu- mours in nerves of stumps, iii. 507; cancer a specific disease, iii. 508; cancerous dys- crasy, iii. 508;predisposingand occasional causes ofcancer,iii.508; Hunter on the dis- posing causes of cancer,iii. 508; prognosis, iii. 509 ; Scarpa on the nature of scirrhus, iii. 509 ; Travers on the occasional inert- ness of scirrhus during life, iii. 509; Bro- die and South's cases, iii. 509 ; treatment of scirrhus and cancer, iii. 509; Leroy d'Etiolles on the statistics of operations for cancer, iii. 510; treatment for effecting dispersion of the tumour, iii. 510; Young, Recamier, and South on compression of scirrhus, iii. 511; removal of the diseased part with the knife or by escharotics, iii. 512; contra-indications, iii. 512; prelimi- nary treatment iii 512;necessary to remove all the diseased parts iii 512; destruction of a cancerous part by caustic, iii. 512; mode of applying the caustic, and the resulting symptoms, iii. 513; Canquoin's employ- ment of chloride of zinc as a caustic for cancer, iii. 513 ; Hellmund's mode of ap- plying Cosme's powder, iii. 514; duration of the treatment, iii. 514; symptoms occa- sionally produced by the arsenical caustic, ANALYTICAL INDEX. 799 iii. 514; internal treatment of cancer, iii. 514; exhibition of narcotics to relieve the pain, iii. 515 ; cancer of the lips and cheek, iii. 515 ; seat and characters of cancer of the lip, iii. 515; microscopic characters of the disease, iii. 515 ; malig- nant but non-cancerous ulceration of the lips, iii. 515 ; treatment of cancef of the lips by extirpation, iii. 515 ; contraindi- cations of the operation, iii. 516 ; mode of operating when the cancer does not spread down beyond the red part of the lip, iii. 516 ; South on the operation in such cases, iii. 516; the operation when the cancer has spread beyond the red edge of the lip, 516; union of the divided parts, even when there has been great loss of substance, iii. 517 ; the ope- ration of chiloplasty, or making a new lip, iii. 517 ; various modes of operating for chiloplasty, iii. 518 ; Dieffenbach and Blasius' operations, iii. 518 ; treatment of cancer of the lip connected with the bone, iii. 518; by operation, iii. 518 ; of cancer of the cheek, iii. 518 ; cancer of the tongue, iii. 518; characters, iii. 518; prognosis, iii. 518 ; treatment, 518 ; by operation, iii. 519 ; mode of operating, iii, 519 ; after- treatment, iii. 520 ; treatment of fungous growths, iii. 520 ; ligature of the lingual artery, prior to the amputation of the scirrhous portion of the tongue improper, iii. 520 ; removal of the tongue by liga- ture, iii. 520; Mirault's operation for liga- ture of the tongue, iii. 521 ; Regnoli's operation for the extirpation of the tongue, iii. 521 ; Arnott's case of malignant tumour of the tongue in which that organ was removed by ligature, iii. 521 ; cancer of the parotid gland, iii. 522 ; diseases of the parotid, iii. 522; characters of swelling of the parotid, iii. 522; diagnosis between the several tumours of the parotid, iii. 523; treatment in scirrhus and medul- lary fungus of the parotid, iii. 523 ; ex- tirpation of the gland a doubtful remedy, iii. 523; arteries in danger of being wounded during the operation, iii. 524 ; Allan Burns on extirpation of the parotid, iii. 524 ; mode of operating for the extir- pation of the parotid, iii. 524 ; Goodlad and Langenbeck on the prior ligature of the carotid, iii. 525 ; after-treatment, iii. 525 ; cancer of the breast, iii. 525 ; symp- toms, characters, and progress, iii. 526; Brodie and South on scirrhus of the breast, iii. 527 ; characters of scirrhus and cancerous ulceration of the breast, iii. 527; development of cancer of the breast as skin cancer, iii. 527 ; characters of cancef of the areola, iii. 528 ; of cancer of the nipple, iii. 528; Astley Cooper on fungous degeneration of the nipple, iii. 528; Astley Cooper on the development of the nipple in the foetus and its subsequent changes, iii. 528 ; Brodie on scirrhus of the nipple, iii. 528; symptoms of cancer of the breast, iii. 529 ; of acute cancer, iii. 529; of chronic cancer, iii. 529 ; Brodie on the puckering in of the skin in mammary cancer, and on its cause, iii. 529 ; appear- ance of scirrhus when cut into, iii. 530; diagnosis between scirrhus and chronic inflammation of the lymphatic vessels, or of the breast gland, iii. 530; symptoms and treatment of the inflammation, iii. 531; symptoms and characters of milk- knots, iii. 531 ; malignant appearance of milk-knots in old women, iii. 532; Scarpa and South's cases of lacteal swelling, iii. 632; diagnosis between scirrhus and scrofulous tumours of the breast, iii. 533 ; and herpetic and psoric affections, iii. 533; and encysted tumours, iii. 533; characters of vesicular scirrhus of the breast, or car- cinoma mammae hydatides, iii. 533 ; this disease a steatomatous degeneration of the gland, iii. 533 ; Astley Cooper on hydatid swellings of the breast, iii. 534 ; Astley Cooper on the symptoms and treatment of cellulous hydatids of the breast, iii. 534 ; Astley Cooper on polypoid hydatids of the breast, iii. 534 ; Astley Cooper on the lobular hydatids of the breast, iii. 535; Brodie on the serocystic tumours of the female breast, iii. 535 ; characters of me- dullary fungus of the breast, iii. 536 ; of the blood-swelling of the breast, iii. 536; ecchymosis of the breast in girls prior to menstruation, iii. 537 ; characters of hy- ' pertrophy of the female breast, iii. 537 ; anatomical appearances of the hypertro- phied breast, iii. 538 ; causes, iii. 538 ; treatment, iii. 538; causes of scirrhus of the breast, iii. 538; prognosis, iii. 539; the question as to propriety of removing a scirrhous breast, iii. 539 ; opi- nions of Cline, Home, Astley Cooper, Brodie and South, iii 539; Brodie on the circumstances permitting the operation, iii. 539; extirpation of the breast, iii. 539 ; mode of operating, iii. 541 ; South on the position of the patient during the operation, iii. 541 ; South's case of fatal venous haemorrhage from the extirpation of the breast, iii. 541 ; South on the after- treatment, iii. 541 ; amputation of the breast, iii. 542; South's opinion thatampu- tation is not preferable to extirpation, iii. 542; relative value of these operations, iii. 542; requisite to remove all diseased Structures, iii. 542 ; operation for relapse of scirrhus after the removal of the dis- ease, iii. 543 ; cancer of the penis, iii. 543 ; 800 ANALYTICAL INDEX. origin, symptoms, causes, and results, iii. 544; diagnosis, iii. 544; treatment,iii. 544; by operation, iii. 544 ; amputation of the penis, iii. 544; South on the recurrence of cancer after amputation of the penis, iii. 544; Cline the younger's case, iii. 544; examination of the organ preliminary to the operation, iii. 544; amputation of the penis by the knife, iii. 545 ; of the glans alone, iii. 545; in the middle of the organ, iii. 545 ; Schreger's mode of amputating the penis near the pubic bones, iii. 545; Langenbeck's operation, iii. 545; Barthe- lemy on the means of preventing the retraction of the urethra, iii. 545 ; occur- rence of after-haemorrhage, and its treat- ment, iii. 546 ; after-treatment, iii. 546 ; amputation of the penis by ligature, iii. 546; relative value of the two operations, iii. 546; South on the relative value of the two operations, iii. 546; Lisfranc's operation for the removal of cancer of the corpora cavernosa, iii. 547 ; cancer of the testicle, iii. 547; definition of sarcocele, iii 547; symptoms and progress of scir- rhus of the testicle, iii. 547; characters and appearances of sarcomatous degene- ration of the testicle, iii. 548 ; these dis- eases occasionally complicated with hy- drocele, iii. 548 ; diagnosis of scirrhous and sarcomatous degenerations of the testicle from other swellings of that organ, iii. 548; from thickening of the cellular tissue of the scrotum, iii. 548 ; characters and causes of that disease, iii. 54* ; treat- ment, iii. 548; by operation, iii. 549; Liston, Key, O'Ferall, and Bennett's cases of sarcomatous scrotum, iii. 549 ; diagnosis of sarcocele from simple hy- drocele, iii. 553 ; from cystic swelling of the testicle, iii. 553 ; characters and ap- pearances of cystic swelling, iii. 553; Astley Cooper on the nature-of the cysts in cystic swelling, iii, 553; removal of the disease by operation, iii. 553; hyda- tids of the testicle, iii. 553; diagnosis of sarcocele from thickening of the tunica albuginea, iii. 553 ; scirrhus of the tunica albuginea, iii. 553; diagnosis of sarcocele from fungus of the testicle or tunica albuginea, iii. 554; from induration of the testicle, iii. 554; from scrofulous swellings, iii. 554 ; from syphilitic swell- ings, iii. 554; from medullary fungus, iii. 554; extirpation of the testicle a doubtful remedy in cancerous degeneration, iii. 555; indications and contra-indications of the operation, iii. 555; Walther and Maunoir on ligature of the spermatic artery in sarcocele, iii. 555; mode of operating, iii. 555; mode of operating for extirpation of the testicle, iii. 556; Aumont's opera- tion, iii. 556; South and Astley Cooper on the retraction of the cord during the operation, iii. 556; degeneration of the spermatic cord, and the operation, iii. 556; South and Cline junior on ligature of the spermatic cord, iii. 557; dressing the wound, and subsequent treatment after extirpation, iii. 557; treatment of after- haemorrhage, iii. 557 ; treatment of un- descended testicle, iii. 557; by operation, iii. 558 ; extirpation of undescended tes- ticle, iii. 558 ; South on the treatment of undescended testicle, iii. 558 ; Paget and Arnott's cases of diseased undescended testicle, iii. 558; cancer of the scrotum, iii. 559 ; characters of chimney-sweep's cancer, iii. 559; Pott and Paris on cancer of the scrotum, iii. 560; Earle's case of chimney-sweep's cancer on the wrist, iii. 560; Astley Cooper and Keate's cases of chimney-sweep's cancer on the cheek, iii. 560; Earle and South on the exten- sion of the. disease to the neighbouring parts, iii. 560; Travers on the resem- blance of the disease to lupus, iii. 560 ; cause and treatment, iii. 561 ; South on the cause of the disease, iii. 561; Pott and Earle on the age at which the disease generally occurs, iii. 561; South's case of recurrence of the disease, iii. 561; cancer of the womb, iii. 561; origin of the disease, and primary symptoms, iii. 562; indica- tions on vaginal examination, iii. 562; Montgomery on the origin of the disease in the ova Nabothi, iii. 562 ; progress of the disease, iii. 562; results of the vaginal examination in the advanced state of the disease, iii. 562; Ashwell, Bayle, and Cayol on the pain in cancer uteri, iii. 562; Montgomery and Ash well's cases of can- cer uteri, iii. 563 ; diagnosis, iii. 563; Simpson on cauliflower excrescence from the os uteri, iii. 563; period of life at which cancer uteri is generally developed, iii. 564; causes, iii. 564; Ashwell on the period of life at which cancer uteri is developed, iii. 564; treatment, iii. 564; by internal and external treatment, iii. 564 ; can only be palliative in true scir- rhus, iii. 564; examination of the parts in cancer uteri by the speculum, iii. 565; mode of introducing the speculum, iii. 565; Simpson on the mode of using the speculum vaginae, iii. 565 ; Osiander on the extirpation of the cancerous neck of the womb, iii. 566 ; modes of operating, iii. 566 ; Dupuytren's operation, iii. 566 ; Cancella and Hatin's specula vaginae, iii. 567 ; von Walther's case of excision of the cervix uteri, preceded by excising the pubic arch, iii. 567; Recamier's opera- tion when the neck of the womb is soft- ANALYTICAL INDEX. 801 ened or destroyed, iii. 567; Lisfranc's operation, iii. 567; Colombat's hystero- tome, iii. 567 ; destruction of the degene- rated womb by caustic, iii. 567 ; Mayor's ligature of the neck of the womb, iii. 567; mode of applying caustic potash to destroy the cancerous cervix uteri, iii. 567; cases in which this proceeding is applicable, iii. 568; extirpation of the whole womb, iii. 568; Struve, Gutberlat, and Wenzel on extirpation of the womb, iii. 568; Langenbeck and Laud-Wolfs cases of extirpation of the cancerous womb, iii. 569; Recamier's cases, of removal of the womb by ligature, iii. 569; Sauter's di- rections for the operation of extirpation, iii. 569; dressing and after-treatment, iii. 569; von Siebold, Langenbeck, Paletta, Holcher, Blundell, and Banner's cases, iii. 570; Delpech, Dubled, and Recamier on the extirpation of the womb, iii. 572; Roux' cases, iii. 577; the difficulty and danger of the operation, iii. 577; Gendrin's directions for the operation, iii. 578; Heath's case of excision of the uterus by the abdominal section, iii. 578 ; Cancrum oris. Fide Mortification. Canella's M., speculum vaginae, iii. 567; Canquoin, M., on the use of the chloride of zinc as a caustic in cancer, iii, 513. Canton, Mr. on the existence of the acarus scabiei, ii. 67. Capuron, M., on an epidemic vaginal catarrh, i. 182. Carruncle :—nature of the disease, i. 154; distinguished from boil and malignant pustule, i. 154; symptoms, i. 154; varie- ties, i. 154; Hunter on the inflammation that produces carbuncle, i. 154; his obser- vation, that there are generally more car- buncles than one, not confirmed by South, i. 155; his opinion that carbuncle has some affinity to boils, i. 155 ; Copeland on an- thrax, i. 155 ; Perrez on the physiology of carbuncle, i. 155; benignant carbuncle, i. 155 ; carbuncle, the consequence of me- tastasis of deleterious matter, i. 155; malignant carbuncle never connected with previous fever, i. 156 ; English sur- geons do not admit the metastatic origin of carbuncle, i. 156; Rayer says it occurs most frequently in spring and summer, i. 156; danger of carbuncle depends on its size, seat, presence of many such swell- ings, the constitution of the patient, and the connecting general disease, i. 156 ; Astley Cooper on the danger of carbuncle on the head and neck, i. 156; South on the rareness of carbuncle on the head, i. 156; general and local treatment of be- nignant carbuncle, i. 156; von Walther on incisions in carbuncle, i. 156; Wise- Vol. in.—68 man on incisions in carbuncle, i. 156; Bromfield on incisions and injections of bark and tincture of myrrh, i. 157; Cooper, Abernethy, Dupuytren, and Rayer, on incisions, i. 157 ; Pearson against inci- sions, i. 157; South's treatment of car- buncle, i. 157; Physick's treatment of carbuncle, i. 157; Coates on the applica- tion of blisters in carbuncle, i. 157; Perrez on the treatment of carbuncle, i. 158 ; Pouteau on the application of caus- tic, and the actual cautery, i. 158 ; treat- ment of malignant carbuncle, i. 158. &.ries, ii. 114; nature and appearances of the disease, ii. 114; Lawrence's definition of caries, ii. 114 ; Miescher on the granu- lations attending caries, ii. 114 ; Syme on the distinguishing character of caries, ii. 115 ; Mayo on the progress of caries, ii. 115; symptoms,ii. 115; diagnosis, ii. 115; Miescher and Syme on the characters of caries, ii. 115,116 ; causes, ii. 116 ; Del- pech on the diseased condition of the bones in syphilis, not caries, but necrosis, ii. 117; Mayo on inflammation as the cause of caries, ii. 117; Miescher on the seat of the various kinds of caries, ii. 1.17; prognosis, ii. 117; general and local treat- ment, ii. 118; Rust, Fricke, Mayo, Law- rence, and Syme on the treatment of caries, ii. 118, 119; removal of the dis- eased bone, ii. 119; caries of the skull bones, ii. 131; situation, causes, and symptoms, ii. 131; South on the consequences of caries, or necrosis in the mastoid process, ii. 132 ; South on necrosis of the vault of the skull, ii. 132; South's case of exten- sive destruction of the vault of the skull, ii. 132 ; South on Caries of the bones of the face, ii. 132 ; South on the disease in bones from mercury and syphilis, ii. 132 ; Syme's case of destruction of the bones of the face, ii. 133; causes and prognosis of caries of the skull-bones, ii. 133 ; treat- ment, ii. 133; caries of the teeth, ii. 133 ; characters and situation of the caries, ii. 134; South on inflammation and suppu- ration in the tooth-socket without caries, ii. 134; symptoms of caries at the root of the tooth, ii. 135; caries of the alveolar process, ii. 135 ; diseased changes in the maxillary antrum, ii. 135; epulis, ii. 136 ; South on the symptoms and treatment of sympathetic disease of the antrum, ii. 136; Liston and South on epulis, ii. 136; causes of caries, ii. 136 ; Coffiniere on toothach as a counter irritant, ii. 137; treatment, ii. 137; remedies to resist the further de- struction of carious teeth, ii. 137; filing and stopping the teeth, ii. 137; destruc- tion of the nerve of the diseased tooth by the actual cautery, or sulphuric acid, ii. -802 ANALYTICAL INDEX. 137; South on the stopping a carious tooth, ii. 137; preventive treatment of caries, ii. 137; treatment of toothach, ii. 138 ; South and Bedingfield on the treat- ment of toothach, ii. 138; extraction of the tooth sometimes necessary, ii. 138; . excision of the carious crown, ii. 138; the different instruments used in the ex- traction of teeth, ii. 138; extraction of the front teeth, ii. 139 ; of the back teeth with the key, ii. 139 ; with the pelican, ii. 139; use of the punch, ii. 139; extraction of stumps and roots of teeth; ii. 140; acci- dents which may occur in extracting teeth, and their treatment, ii. 140; occa- sional consecutive haemorrhage, ii. 140; inflammation and suppuration of the gum, ii. 141 ; caries of the alveolar process, ii. 141; South on the consecutive haemor- rhage in the haemorrhagic diathesis, and its treatment by the actual cautery, ii. 141; Blagden, South and Davenport's cases, ii. 141; Cortez, Cullen, Kendrick, and Dr. Ryan on the treatment of the conse- cutive haemorrhage, ii. 143 ; South on the necessity of adopting preventive measures immediately after the extraction of a tooth, when the haemorrhagic diathesis is known to exist, ii. 144 ; tooth-fistulas, ii. 144 ; carcinomatous excrescences on the gums, ii. 144 ; treatment, ii. 144. Carlisle's, Sir A., tourniquet, and its mode of application, i. 332. Carmichael, Mr., on severe phlebitis i. 93; injection of a strong solution of nitrate of silver in gonorrhaea, i. 191 ; objections to the terms ■ syphilis, syphyloidal, and pseudo-syphilis, ii. 82; bases his arrange- ment of venereal complaints on the cha- racter of the eruption, ii. 82 ; does not admit the existence of mercurial disease, ii. 107 ; on eczema mercuriale, ii. 110; case of ligature of the gluteal artery, ii. 535 ; case of excision of the head of the femur, iii. 736. Carotid aneurism, ii. 507. —-------artery, common, ligature of, ii. 509 ; tying the external carotid, ii. 512. Carpue's Mr., cases of the Taliacotian ope- ration, iii. 577. Carpus, fracture of the bones of, iii. 615 ; exarticulation of the metacarpal bones at, iii. 721. C arswell, Dr., on the gewuscarcinoma, iii. 445. Cartilage, Inflammation of. See In- flammation of the Joints. Cartilages of the larynx, fracture of, i. 581. ---------costal dislocation of, ii. 216. Catheter, introd'uction, iii. 148 ; straight in- troduction of, iii. 148; female introduc- tion of, iii. 150. Catheterism, forcible, iii. 145. Cauterization, iii. 630. Cautery, actual, iii. 631. Cayol, M., on the pain in cancer uteri, iii. 562. Celsus, on the extirpation of the tonsils by cutting and by tearing out, i. 164 ; on the removal of the relaxed uvula by cutting, i. 166; on the use of the ligature for wounded vessels, i. 354 ; on the applica- tion of a ligature above a viper's bite, i. 390; observations on the innocuous quali- ties of the poison of serpents when intro- duced into the mouth confirmed by Rus- sell, i. 390 ; on rubbing the ends of the broken bone together in cases of false joint, ii. 15. Cerebral Hernia, ii. 362. Cestoni, M., on the acarus scabiei, iii. 67. Chabert's M., artery-compressor, i. 331., Champesme's, M., mode of amputating at the shoulder joint, iii. 713. Chauliac's, Guy de, account of the opera- tions of the Arabian physicians in false joints, ii. 18 ; on ligature of the hernial sac for its radical cure, ii. 283. Chaussier's, M., cases of actual protrusion of the heart, ii. 361 ; experiments on the excision of joints, iii. 727. Chaumet's M., case of partial resection of the clavicle, iii. 764. Cheek-bones, fracture of, i. 578, Cheek, cancer of, iii. 518. Cheselden, Mr., on ligature of the tonsils, i. 164; his operation preferred by Else, i. 164; on the immovable apparatus for fractures, i. 553; case of large urinary calculus, iii. 273 ; on the high operation for stone, iii. 306 ; operation for stone, iii. 309 ; cases of tumours on nerves, iii. 506. Chesman's, Mr., case of spina bifida, iii. 186. Chest, Wounds of the, i. 481; either superficial or penetrating, i. 482; treat- ment of superficial cuts and sabre wounds, i. 482; consequences and treatment of bruises and shot Wounds of the coverings of the chest, i. 482 ; penetrating wounds of the chest, i. 482 ; indications of a pene- trating wound, i. 482; South on the ex- amination with the probe, &c, in pene- trating wounds of the chest, i. 482 ; South on the condition of the lungs when the chest is opened, i. 483 ; Williams' experi- ments and conclusions, i. 483; Astley Cooper on the signs of wounded lungs,i. 483; Hennen on the course taken by balls in wounding the chest, i. 483 ; Maiden and Sir W. Blizard's case of penetrating wound of the chest, i. 483 ; Andrews' case of penetrating wound of the chest, with injury to the lung, i. 485 ; Astley ANALYTICAL INDEX. 803 Cooper's case of wound of the intercostal muscles by an iron spindle, i. 487 ; Ever- ard Home on the appearances in the lungs thirty-two years after their having been wounded by a ball, i. 487; Hennen and Gregory on the prognosis of wounds of the chest, i. 489 ; varieties of penetrating wounds of the chest, i. 488 ; simple pene° trating wounds of the chest, and their treat- ment, i. 488; penetrating wounds of the chest complicated by the presence of foreign bodies, i. 488 ; Larrey's case of ex- cision of a portion of a rib for the removal of a ball, i. 489 ; presence of bullets in the chest without causing inconvenience, i. 489 ; instance of a ball remaining in the lungs for twenty years without causing mischief, i. 489 ; occurrence of haemor- rhage in penetrating wounds of the chest, i. 489 ; symptoms of haemorrhage, i. 489 ; the most certain and determinate signs of extravasation of blood in the chest, i. 489 ; I the less certainand constant symptoms, i. 490 ; effects of the extravasation of blood into the cavity of the chest, i. 490 ; Hen-- nen on the occurrence of priiriary and I secondary haemorrhage in incised or punc- tured wounds of the chest, i. 490 ; very difficult to determine the source of the haemorrhage in penetrating wounds of the chest, i. 490 ; injury of the intercostal artery, i. 490; Richter's piece of card- board, and Reybard's canula useless in such cases, i. 490, 491; Graefe's case of fatal gun-shot wound of the intercostal artery, i. 491; various plans for stanching] bleeding from the intercostal artery pro- posed by Gerard, Goulard, Leber, Rey- bard, Nevermann, Benj. Bell, Lottery, Quesnay* Bellocq, Harder, Desault, Sa- batier, Medin, Assalini, and Grosheim, i. 491, 492 ; Nevermann's mode of ope- rating, i. 492 ; objections to these modes of proceeding, i. 492 ; treatment of bleed- ing from an intercostal artery, i. 492 ; wounds of the internal mammary artery, i. 493; wounds of the large vessels in the cavity of the chest speedily fatal, i. 493; stanching of bleeding from a wounded lung, i. 493; Vering's objec- tions to the union of penetrating wounds of the chest, i. 494; Astley Cooper on the danger attending wounds of the lungs, i. 494; Hennen on the immediate treat- ment of penetrating wounds of the lungs, i. 494, emphysema, i. 495; causes of emphysema, i. 495 ; Astley Cooper, Hennen, and South on emphysema, i, 495; the escape of air from the lungs into the cavity of the pleura, i. 496 ; Hen- nen's case oi secondary emphysema, l. 496; treatment of emphysema, i. 497; Abernethy on the use of a broad chest- bandage in emphysema,i. 497 ; South on the practice of sucking or pumping to ex- tract the air in the cavity of the chest, i. 497 ; Hennen on the healing of w'oupded lung, i. 497 ; protrusion of a portion of lung in wounds of the chest, i. 497; Hennen on the protrusion of a portion of lung, i. 497; treatment of the conse- cutive inflammation of the lung and pleura, i. 498; consequences of the in- flammation, i. 498 ; Astley Cooper on the treatment of traumatic pneumonia, i. 498 ; wounds of the heart, i. 498 ; symp- toms of wounds of the heart, i. 498 ; Speyer on the peculiar causes of death at different periods in wounds of the heart, i. 499 ; case of fatal wound of the heart by a broken rib, i. 499; Featherstone and Dr. Babington's cases of fatal bayonet- wound of the heart, i. 499 ; case of lace- ration of the pericardium, and superficial wound of the heart, 500; Hennen, Four- nier, and Ploucquet's cases of foreign bodies in the heart, i. 500; treatment of wounds of the heart, i. 500 ; wounds of the pericardium, i. 500; Astley Cooper and Hennen's cases of wounds of the pericardium, i. 500, injuries of the gullet, thoracic duct, diaphragm, and spinal marrow, i. 501 ; symptoms of wounds of the diaphragm, i. 501. Cheston's Mr., case of gangrene of the bladder from retention, iii. 128. Chevalier, Mr., on tying the tonsils, i. 164 ; case of puncturing the dura mater, to remove effused blood from beneath it, i. 447. Chevalier's, M., case of removal of the inverted womb by ligature, ii. 388. Chiloplasty, the operation of, iii. 517. Chilblains:—i. 149; symptoms and results, i. 149 ; Hunter mentions another inflammation very like chilblains, i. 149 ; seat of chilblains, i. 149; treatment, i. 149 ; South on the mustard liniment of St. Thomas' Hospital in the treatment of chilblains, i. ISO ; treatment of ulcerated chilblains, i. 150 ; of gangrenous chil- blains, i. 150 ; prevention of chilblains, i. 150. Chimney-sweep's cancer, iii. 559. Chopart's, M., case of inclusion of a nerve in the noose of a ligature placed on an artery, i. 339 ; case of simple dislocation of the spine, i. 586; mode of operating in ovarian dropsy, iii. 209. Choulart, M., on the influence of spinal curvature on the transverse diameter of the pelvis, ii. 427. Chrestien, M., on gold and its prepara- rations in primary and secondary syphi- lis, ii. 101. 804 ANALYTICAL INDEX. Church, Mr., on tartar emetic in strangu- lated hernia, ii. 292. Churchill, Dr., on the treatment of lace- rated perineum, ii. 37. Cirsocele, ii. 575. Cittadini's, M., case of false joint, in which rubbing the ends of the broken bone together was practised, ii. 15 ; suc- cessful operation for sawing off the ends of the broken bone, ii. 20. Civiale, M., on the introduction of the straight catheter, ii. 149 ; operations for stone on infants, iii. 297. Clanny's, Dr., case of enlargement of the tongue, iii. 384. Clarke, Sir J. M., on the length of time during which prolapse of the womb is forming, ii. 371 ; on the size and shape of the prolapsed'organ, ii. 371 ; on the consecutive ulceration of the vagina, ii. 371; case of procidentia uteri, with se- paration of the pelvic bones, ii. 374 ; on the after-treatment of procidentia uteri, ii. 375; on the application of injections, ii. 376 ; on the treatment of the ulcerated vagina, ii. 376; objections to sponge as a pessary, ii. 376; on the corrosion of pessaries in the passage,, and on the deposit of calculous matter on them, ii. 378; on polypus of the fundus uteri as a cause of inversion, ii. 384 ; on the cha- racter of the discharge in inverted uterus ii. 385; on the treatment of chronic inversion, ii. 387; of recent inversion, ii. 387 ; on the diagnosis between chronic inversion and polypus uteri, ii. 387; on the treatment of the inverted womb, complicated with procidentia, ii. 388; case of removal of the inverted womb by ligature, ii. 38s; on prolapse of the va- gina, ii. 389; on the symptoms of prolapse , of the vagina, ii. 389; on the causes and symptoms of posterior prolapse of the va- gina, ii. 390; on the treatment of pos- terior prolapse, ii. 390. Clarke's, Dr. J., case of removal of the inverted womb by ligature, ii. 388. Clavicle, fracture of, i. 602; dislocation of, ii. 217; resection of, iii. 763. Clay, Dr., on the large operation for ovarian dropsy, iii. 212. Clement?s, Mr., case of successful opera- tion for strangulated umbilical rupture during pregnancy, ii. 340. Cline's, Mr., experiments to cause the ab- sorption of the pus in lumbar or psoas abscess, i. 211; on the lengthening and shortening of the diseased limb in hip disease, i. 284; experiments with the broad ligature on arteries, i.,386 ; case of musket-shot wound of the bladder, the ball remaining in that viscus, and being after- wards extracted by operation, i. 529; case of fracture of the spine without dis- placement, i. 585; case of cure of un- united fracture, ii. 18; ease of double umbilical rupture, ii. 344; case of the existence of several aneurisms in the same person, ii. 477; cases in which the femoral artery was tied with a broad tape, the ligature being removed some hours afterwards, ii. 496; case of obli- teration of the vena eava inferior, ii. 569 ; case of varix of a deep-seated vein, ii. 570; on excision of piles, ii. 585; case of impending suffocation from ra- nula, iii. 121 ; case of stone in one of the submaxillary ducts, iii. 122; case of very large hydrocele, iii. 221; case of suppuration of the kidney from impac- tion of calculus in the ureter, iii. 271; case of large calculus, iii. 273 ; case of on old man operated on for stone, iii. 297; gorget, iii. 321; on the ques- tion as to the propriety of removing a scirrhous breast, iii, 539; the first experimenter with vaccine lymph, iii. 622. Cline's, Mr., jun., eases of after-bleeding, in which the actual cautery was em- ployed, i. 347; clinical observations on after-hemorrhage, and on the use of the actual cautery in such eases, i. 347; experiments on arteries, i. 351 ; on the disposition of hydrophobic animals to use their weapons of offence, i. 407; directions for the excision of the part bitten by a mad dog, i. 411; on punc- turing the brain in wounds of the dura mater, i. 439; case in which he per- formed the operation for trepanning the spine, i. 590; details of the case, i. 590; clinical observations on the case, i. 590 ; on the use of caustics to destroy the cartilaginous ends of broken bones in false joints, ii. 17; case of cure of false joint by caustic potash, ii. 17 ; reduction of an old dislocation of the humerus, ii. 204; case of hydrocele in front of an inguinal rupture, ii. 323; case of aneurism of the anterior tibial artery, ii. 543; on tumours of nerves in stumps, ii. 507; case of amputation of the penis, iii. 544; on ligature of the spermatic cord, iii, 557 ; on arteriotomy, iii. 612. Clitoris, enlargement of, iii. 399. Cloquet's, M., treatment of fractured cla- vicle, i. 605; on the solution of the chloride of lime in the treatment of foul, gangrenous, or torpid ulcers, ii. 44; on the statistics of rupture, ii. 265; explana- tion of the manner in which reduction en masse takes place, ii. 275; on thesponta- ANALYTICAL INDEX. 805 neous return of the hernial sac into the ab- domen, ii. 281; on Nuck's canal, ii. 328; case of lumbar rupture, ii. 348 ; on thy- roid rupture, ii. 352; on elongation of the womb in cases of prolapse, ii. 372 ; on the formation of calculi in the dis- placed bladder, consequent on prolapsus uteri, ii. 372; on consecutive displace- ment of the rectum, ii. 372 ; case of the existence of numerous aneurisms in the same person, ii. 477. Clossius', M., explanation of the lengthen- ing of the limb in hip-disease, i. 285. Club-foot, ii. 445. Coates, Dr., on the application of blisters in the treatment of carbuncle, i. 157; on ligature of the common carotid, ii. 564; case in which the bronchocele ultimately enlarged, after the ligature of the superior thyroid, iii. 393. Coccyx, fracture of, i. 595; dislocation of, ii. 215. Cock, Mr., on the reduction of the dis- located femur by placing the foot between the thighs and making extension and rotation, ii. 242; case of sixpence in the hvrynx, iii. 114. Cephalaematoma, iii. 167. CoFFiNiiiRE, M., on toothach as a counter- irritant, ii. 137. Coherence, unnatural :—definition, iii. 13; causes and mode of union, iii. 13; contraction and closure of the outlets of the body, iii. 13; congenital closure of the outlets, and congenital union of parts which should be separate, iii. 14 ; con- dition of the parts when an outlet is closed, iii. 14; treatment of parts pre- ternaturally united, iii. 14; treatment of deforming cicatrices, iii. 14; treat- ment of narrowing and closure of the outlets, iii. 15; of imperforation, iii. 15; union of the fingers and toes, iii. 16; causes, iii. 16; the operation for its treatment, iii. 16; circumstances which contra-indicate the operation, iii. 16; after-treatment, iii. 16; result of the operation often unsatisfactory, iii. 16; mode of operating, and treatment to prevent reunion, iii. 17; Dupuytren and Rudtorffer's plans to prevent re- union, iii. 17; Zeller's operation, iii. 17; the growing together of the joint-ends of bones, or anchylosis, iii. 18; defini- tion, iii. 18; sub-divisions, iii. 18; causes, iii. 18; nature of the connecting substance, iii. 19; treatment, iii. 19; Dr. Barton's operation on the anchy- losed femur, iii. 19; von Wattman^s operation on the humerus m anchylosis of the elbow, iii. 19; treatment of the slighter degrees of false anchylosis, iii. 20; of the more severe forms, iii. 19; the operation in contraction of the knee- joint, iii. 20; occasional results, iii. 20; growing together and narrowing of the nostrils, iii. 21 ; characters, iii. 21 ; the operation for contracted nostrils, iii. 21; after-treatment, iii. 21 ; unnatural adhe- rence of the tongue, iii. 22; direct causes, iii. 22; diagnosis, iii. 22; treatment, iii. 22 ; of the tumour under the tongue, iii. 22; division of the frenum, iii. 23; treatment of adhesion of the tongue to the cheek, iii. 23; South on adhesion of the tongue to the cheek, iii 23; consecu- tive accidents, iii. 23; haemorrhage from the raninar artery, iii. 23; danger of suffocation from the tongue turning backwards, iii. 23; growing together of the gums and cheeks, iii. 24;, causes, prevention, and treatment, iii. 24 ; nar- rowing and closure of the mouth, iii- 24; complete closure a very rare mal- formation, iii. 24; causes of narrowing, iii. 24; symptoms, iii. 24 ; treatment, iii. 24; Dieffenbach and Werneck's ope- rations,' iii. 25; treatment of narrowing of the mouth, with loss of substance of the lips, iii. 2"); narrowing of the oeso- phagus, iii. 26; causes, iii. 26; conse- quences, iii. 26; symptoms of simple or membranous stricture, iii. 26; cal- lous narrowing of the oesophagus, iii. 27; of scirrhous hardening, iii. 28; expansion of the walls and its causes, iii. 28; ulceration of scirrhous and callous, cartilaginous, and bony stricture, iii. 28 ; Meyer and Gendrin's cases of stric- tured oesophagus communicating with the bronchus or trachea, iii. 28; narrowing of the oesophagus from fungous growths, iii. 28; from swellings in the neigh- bourhood, iii. 29; symptoms of dy- sphagia lusoria, iii. 29; spasmodic stricture, iii. 29; angina impetiginosa, symptoms, characters, and treatment, iii. 29; prognosis in stricture of the oeso- phagus, iii. 29; Astley Cooper's case of stricture of the oesophagus ulcerating externally, iii. 30; treatment of stricture caused by chronic inflammation, iii. 30; introduction of the oesophageal sound, iii. 30; mode of operating, iii. 31; intro- duction of the sound through the nostril improper, iii. 31; use of a sound with a lead stilette, iii, 31 ; South's objection to the protrusion of the tongue prior to the passage of the oesophagus-bougie, iii. 32; Astley Cooper's case of stricture of the oesophaguS, in which a false pas- sage was made through into the anterior mediastinum, iii. 32; dilatation of the stricture, and subsequent treatment, Hi. 806 ANALYTICAL INDEX. 32; use of caustic bougies very dan- gerous, iii. 32 ; Jameson and Fletcher's instruments, iii. 32 ; general treatment for callous, scirrhous, and spasmodic stricture, and for dysphagia lusoria, iii. 33; use of the oesophageal sound for the passage of strong broths, iii. 33; dysphagia paralytica atonica, iii. 33; narrowing and closure of the rectum, iii. 33; closure of the rectum always a mal- formation, iii. 34; stricture rarely con- genital, iii. 34; congenital closure of the rectum, iii. 34; symptoms, iii. 34; Wolff's case of imperforate anus, iii. 34; the operation for imperforate anus, iii. 34; the operation to be performed when there is not any trace of an anus, iii. 35; Amussat's, operation, iii. 35; South's case ofadherence of the two portions of the ileo-colic valve, causing obstruction to the passage of the meconium, iii. 35; the operation for the rectum opening into the vagina, iii. 36; Barton and Dieffenbach's operations, iii. 36; opening of the rec- tum into the urethra, iii. 37; the opera- tion, iii. 37;. opening of the rectum into the urinary bladder, iii,, 37 ; Fergusson's case of opening of the rectum into the bladder, iii. 37; Cruveijhier's case of opening of the rectum under the glans penis, iii. 37; the formation of an ar- tificial anus at the lower end of the colon, iii. 37; the mode of operating, iii. 37; Callisen and Amussat's. mode of ope- rating, iii. 38; Pi'lore's case, in which he made an artificial anus in the right side, by opening the caecum, iii. 38; Freer and Pring's cases, of operation for artificial anus at the lower end of the colon, iii. 38; congenital narrowing of the amis, iii. 33;. South's case of im- perforate anus, opening under, the glans penis, iii.. 39 ;> stricture of the rectum, iii. 39; spasmodic contraction of the anus, iii. 39 ;. causes* iii. 39 ; symptoms, iii. 39; examination of the anus, iii. 41; fissure of the rectum, iii. 41; Brodie on ulceration of the rectum -in connexion with spasmodic- contraction of the .sphincter, iii. 41;. Bushe on the spas- modic contraction of the anus, iii. 41 ; spasmodic contraction distinguished from narrowing, iii. 41 * treatment,, iii. 41; division of; the sphincter, iii. 42; after- treatment, 42; narrowing of the rec- tum, depending on chronic inflammation, iii. 43 ; characters, iii. 43 ; progress and terminations of the disease,f ii^ 43 ; local results of stricture, j ii. 44; Brodie on the occurrence of symptoms of strangulated hernia in some cases of stricture, iii. 44; Astley Cooper's case of stricture of the rectum, iii. 44; changes produced in the tissues of the gut by chronic inflamma- tion, iii. 44; Brodie on the post-mortem appearances in stricture of the rectum, iii. 44; Lawrence on the spongy excres- cence of the rectum, iii. 44 ; situation of the stricture, iii. 44; excrescences grow- ing from the valvulae conniventes, iii. 45; examination of the rectum for stricture, iii. 45 ; Lawrence and Bushe on stricture of the rectum, iii. 46;» White, Salmon, Charles Bell,Colles,Allan, Liston,Syme, Brodie and Bushe on the seat of stricture in the rectum, iii. 46; immediate cause of stricture, iii. 47 ; prognosis, iii. 47 ; Brodie on the necessity of early treatment in stricture Of the rectum, iii. 48 ; treat- ment, iii. 48; Brodie on the distention of the bowel above the stricture by faeces, iii. 48; stretching the contracted part, iii. 48; introduction of bougies, iii. 49 ; Brodie and Lawrence on the use of bougies, iii. 49,50 ; Bxodie on the internal application of mercurial ointment in stricture of the rectum,, iii. 50; dilatation by prepared gut, and by metallic dilators, iii. 50; in- cision of the stricture, iii. 51; Copeland and Brodie on incision of the stricture, iii. 51 ; extirpation of tuberculous ex- crescences, iii. 51; use of the caustic bougie, iii. 51; treatment of fistulae complicating the stricture, iii. 52; of cancerous stricture, iii. 52; operation for the removal of cancerous stricture, iii. 52; stricture caused by a cicatrix, iii. 53; narrowing of the anus from Union between, the nates, iii. 53; treatment of closure of the rectum from stricture, iii. 53 ; growing together, and unnatural clo- sure of ihe prepuce, iii. 53 ; phimosis and paraphimosis, iii. 53; phimosis conge- nital or acquired, iii. 53 ; consequences, iii. 53; after puberty, iii. 54; causes of accidental phimosis, iii. 55; symptoms, iii. 55 ; consequences of venereal ulcers on the corona glandis, complicated with phimosis, ii. 55 ; treatment of phimosis, iii. 55 ; operations by circumcision and slitting up the prepuce, with or without removal of the flaps, iii. 55 ; , circum- cision, iii. 55 ; the Jewish operation, iii. 55; South on the Jewish operation, iii. 55; slitting up the prepuce, iii. 56; after-treatment, iii. 56; the preference given to the latter operation, iii. 56; vision of the inner fold of the prepuce, iii. 57; Langenbeck, Begin,, and Vidal de Cassis' operations, iii. 58; treatment of phimosis, complicated with union, partial or complete, of the prepuce of the glans, iii. 58 ; connexion of the glans with the prepuce, by bands, iij. 58; treatment of ANALYTICAL INDEX. 807 phimosis from inflammation, iii. 59; from excoriation or putrefaction of the cheese-like matter, iii. 59 ; treatment of syphilitic phimosis, iii. 59 ; Pigne on the treatment of syphilitic phimosis, iii. 59 ; the operation rarely required for inflam- matory and venereal phimosis, iii. 59; the introduction of the catheter requisite, when the issue of the urine is impeded by the constriction of the phimosis on. the urethra, iii. 60; the origin and symptoms of paraphimosis, iii. 60; treatment, iii. J 60; reduction of the prepuce, iii. 60; j treatment of the accompanying inflam- mation, iii. 61 ; South on the reduction of paraphimosis, iii. 61; the operation for paraphimosis, iii. 61; treatment if suppuration have occurred, iii. 62; after- treatment, iii. 62; constriction of the! penis by threads, tape, rings, &c, iii. 62; symptoms and treatment, iii. 62;. nar- rowing and closure of the urethra, iii. 62; stricture of the urethra of more fre- quent occurrenc than in any other outlet, iii. 63; symptoms, iii. 63; Brodie on incontinence ofurine in stricture, iii. 64; extravasation of urine from rupture or sloughing of the urethra behind the stric- ture, iii. 64; Brodie on extravasation of urine from ruptured urethra in stricture, iii. 64 ; Brodie on abscessses communi- cating with the bladtfer in old cases of stricture, iii. 64; changes in the urethra in old strictures, and the attendant symp-. toms, iii, 65; Brodie on the complication of stricture with enlarged prostate, iii. 65; Brodie's case of enlargement of the urethra from stricture, iii. 65; Brodie on the formation of cysts of the urethral mu- cous membrane in stricture, iii. 66; Bro- die on the occcurrence of rigors and fever in cases of stricture, iii. 66 ; causes of stricture, iii. 66; Brodie on the existence in old strictures of an indurated mass at the lower portion of the penis, iii. 67; seat and characters of stricture, iii. 67; Hunter's description of three forms of stricture, iii. 67 ; Brodie on the original seat of stricture, iii. 68; diseases liable to be confounded with stricture, iii. 68; diagnosis, iii. 68; prognosis, iii. 68; treatment, iii. 69 ; mode of determining the seat of the stricture, iii. 69 ; Bro- die on the use of a full-sized bougie in determining the seat of the stricture, iii. 70 ; preparation of common bougies, iii. 70 ; Astley Cooper, Abernethy and Bro- die on the passing the bougie, iii. 71 ; Astley Cooper and Abernethy on the use of metallic bougies, iii. 71; Brodie on the treatment of stricture with bougies, and on their applicability to the respec- tive kinds of stricture, iii. 71; Brodie's directions for the introduction of the bougie, iii. 73 ; South on the danger of using plaster bougies, iii. 73 ; South on the introduction of the bougie, iii. 74 ; South on the general treatment of stric- ture, iii. 75; the time the bougie should be left in the urethra, and the frequency of its introduction, iii. 75 ; precautions to be taken when the instrument is left in the urethra, iii. 76 ; gradual increase in the size of the intruuient used, iii. 76; I Arnott's oil-silk tube, iii.. 76; action of the bougie, iii.. 771 symptoms occasion- ally produced by it, iii. 77; Astley Cooper and Abernethy on haemorrhage from the urethra.after passing the bougie, iii. 77 ; Astley Cooper and South on the practice to be adopted when a laceration of the urethra by the bougie is suspected,iii. 77; destruction of the stricture by caustic, iii. 78; by ulceration to be rejected as dangerous, iii. 78; Brodie on the destruc- tion of the stricture by ulceration, iii. 78; cauterizing a stricture from before back- wards, iii. 78;. preparation of armed bougies, iii. 78; Hunter, Home and Whately on the use of the armed bougie, iii. 79; objections to this modeof cauteriza- tion, 79; cauterizating the walls of the stricture, iii. 79; Whately and Arnott on cauterizing the walls of the stricture, iii. 79; use of bougies armed with caustic potash, iii, 80; Whately and Lawrence on the use of bougies armed with caustic potash, iii. 8Q; Ducamp's mode of cau- terizing the urethra, iii. 80 ; subsequent treatment, iii. 81; Ducamp's mode of di- lating the urethra after cauterization, iii. 81 ; Ducamp's caution respecting the use of caustic,.iii. 82; Lallemand, Segalas and Tanchou's caustic-holders, iii. 83; relative advantages of the treatment by bougies and by caustic, iii. 83; Astley Cooper, Brodie, Lawrence and South on the use of the armed bougie, iii. 84; cut- ting into the stricture, and subsequent dilatation, iii. 85; Jameson's treatment of stricture, iii. 85; formation of false pas- sages, iii. 86; treatment, iii. 86; South on the treatment of false passages, iii. 86; congenital closure of the urethra, ii. 86; treatment, iii. 86; hypospadias and its treatment, iii. 87 ; closure and narrowing of the vagina, iii. 87; congenital or acci- dental, iii. 87; symptoms of congenital closure of the vagina, iii. 87; narrowing of the vagina, i!i. 88 ; treatment, iii. 88 ; operation for complete closure of the va- gina by the hymen, iii. 88; division of the united labia, iii. 88; South on the treatment of closed vagina in infants, iii. 808 ANALYTICAL INDEX. 89; the closure more or less deep in the vagina, iii. 89; complete closure of the vagina without signs of menstruation, iii. 89; partial closure or bands of the va- gina, iii. 89; Locock's case of bands in the vagina from previous difficult labour, iii. 89; Kennedy and Labat's cases, iii. 90; treatment of narrowing of the vagina, iii. 90; treatment after the escape of the retained catamenia, iii. 90; closure and narrowing of the mouth of the womb, ii. 90 ; congenital or acquired, iii. 90; characters, iii. 91; consequences-of the retention of the catamenia, iii. 91; treatment by operation, iii, 91; after- treatment, iii. 91; operation for closure of the os uteri from scirrhous degenera- tion, iii. 91 ; the operation when the os uteri is completely closed, or cannot be felt, iii. 92. Cole's, Mr.,mode of am putating at the hip- joint by the circular cut, iii. 689. Colles, Mr., on the ingrowing of the nail, i. 222; on the disease of the nail liable to be mistaken for gout, i. 222 ; condemns Cooper's operation for ingrowing of the hail, i. 224 ; operation for the treatment of that disease,.i. 225; on onychia ma- ligna, i. 226; plan of treatment, i. 226 ; doubts whether a syphilitic infant can infectits nurse,unless she have ulceration of the nipple, ii. 105; case of ligature of the subclavian above the clavicle, ii. 519; on the seat of stricture in the rectum, iii. 46. Colomhat's, M , mode of reduction of dis- located femur, ii. 241; hysterotome, iii. 567. Colomre's, M., experiments respecting sta- phyloraphy on the dead body, ii. 30. Come's, Frere, operation with the lithotome cachi, iii. 326. Compression: Pressure on the Brain, i. 445; causes, i. 445~; symptoms, i. 445; Guthrie on the stertor an uncertain sign of compression, i. 445; Guthrie on a pe- culiar whiff or puff from the corner of the mouth a sign of compression, i. 445; prog- nosis, i. 446; treatment, i. 446 ; South on mercury in compression, i. 446; removal of extravasated blood either by absorp- tion or trepanning, i. 447 ; signs indica- tive of the propriety of trepanning, i. 447; removal of the extravasation after the performance of the operation, i. 447; South on the removal of the extravasated blood after the operation, i. 447; South, Pott and Brodie on puncturing the dura mater,when the extravasation lies beneath it, i. 447 ; Pott on the extravasation be- tween the meninges, or on the surface of the brain, i. 447; Chevalier and Ogle's| cases, i. 447; Hunter, Astley Cooper, Abernethy and Lawrence on puncturing i the dura mater to evacuate the effused blood, i. 448; South on the operation of trepanning to remove effused blood, i. 448. Concussion of the Brain, i. 449; symp- toms, i. 449; Astley Cooper and South on the state of the pulse in concussion, i. 449; Astley Cooper and Larrey's cases of loss of memory, &c, after concussion, i. 450; Hennen on the loss of certain faculties from concussion, i. 450; Astley Cooper on the condition of the alimentary canal and bladder during concussion, i. 450; the diagnosis of concussion from compression, i. 451; concussion and com- pression may occur together, i. 451; difficult to distinguish between drunken- ness and concussion or compression, i. 451; in drunkards delirium tremens may succeed concussion, i. 451; inflammation of the brain may be connected with con- cussion, i. 451; primary and consecutive changes in the brain from concussion, i. 451; Dupuytren distinguishes between commotion and contusion of the brain, i. 451; Walther and Astley Cooper on the symptoms of laceration of the brain, i. 451; Astley Cooper on the condition of the brain in moderate concussion, i. 451; causes of concussion, i. 452; Astley Cooper on the causes of concussion, i. 452 ; Schmucker's case of concussion, i. 452; prognosis, i. 452; treatment, i. 452; South on the treatment of concussion, i. 452; Astley Cooper's case of enormous blood-letting in concussion, i. 453; after- treatment, ii 453. Cook's, Dt., case of fistulous opening in the stomach, i. 523. Cooper* Sir Astley, on the effects of frost- bite, ii 145; observations on the effects of too suddenly warming a frozen or be- numbed limb, i. 148; on the danger of carbuncle on the head and neck, i. 156; on incisions in carbuncle, i. 157; did not consider any benefit was derivable from the excision of the relaxed uvula, i. 166; on chronic abscess of the breast, i. 173; on the treatment of fissured nipples, i. 174; on the period when gonorrhoea first shows itself after infection, i, 176; or. the primary symptoms of gonorrhoea, 1. 176; on the actual seat of the discharge, i. 176; on the post-mortem appearance? in gonorrhoea, i. 177; on the occurrence of haemorrhage jn severe gonorrhoea, i. 177; on the influence of constitutional causes on gonorrhoea, i. 179; on the sympathetic bubo of gonorrhoea, i. 188 ; on the treatment of gonorrhoea, i. 191; / ANALYTICAL INDEX. 809 observes that gonorrhoea is difficult to cure in strumous subjects, i. 192; on the re- medies for chordee, i. 192; on gleet and its infectious nature, i. 195; on the dis- tinction between gonorrhoea or gleet, and I abscess of the lacunae, i. 195; on the | treatment of gleet, i. 195; on the use of cubebs in gonorrhoea, i. 197; on syphi- litic swelling of the testicles, i. 200; mentions enlargement of the prostate in old age, inflammation of the neck of the bladder, a stone passing through the ure- ter, or pressing on the commencement of the urethra from the bladder, as causes of swelled testicle, i. 200 ; on the symp- toms and progress of orchitis, i, 201; on adhesion and thickening of the tunica vaginalis, i. 202; on suppuration of the testicle, i. 202; on wasting of the testi- ticles, as-caused by inflammation, i. 202; on the more frequent seat of the disease in the globus major, i. 202.; on the symp- toms of psoas abscess, i. 208; on the origin of psoas and lumbar abscess in inflammation of the spine and inter-ver- tebral substance, i. 209; remarks that lumbar abscess must be allowed to take its course, i. 211; this opinion contro- verted by South, i. 211; recommends Abernethy's plan of treatment, i. 213; on the treatment of the sinuous cavities resulting from lumbar abscess by injec- tions, i. 214; says the application of a blister will often bring away the nail in cases of its ingrowing, i. 224 ; this opi- nion contravened by South, i. 224; ope- ration for the removal of the diseased portion of nail, i. 224; condemned by Colles and South,' i. 224; on the removal of the nail with its secreting surface in onychia maligna, i. 226 ; on gonorrhceal rheumatism and ophthalmia, i. 241; case of gonorrhceal rheumatism and ophthal- mia, i. 242 ; on the second stage of hip- disease, i. 280; on the bursting of ab- scesses of the hip-joint, i. 281; on the lengtheningof the limb from effusion into the joint, i. 286; on morbus coxae senilis, i. 289; on the manner in which vertebral caries is cured by anchylosis, i. 314; on vertebral caries in the neck, i. 315; on the union of wounds, i. 320; on adhesive inflammation, i. 321; on the cat-gut liga- ture, i. 339; case of accidental torsion, i. 344; on the application of a ligature above a viper's bite, i. 3.90; on fracture of the frontal sinuses, i. 431; on apparent fracture and depression of the skull, i. 431; on the treatment of simple fracture with depression without the trephine, i. 431 ; on the necessity for raising or re- moving the depressed bone in compound fracture, i. 433; case of lodgment of a ball in the frontal sinuses, i. 435; case of fatal perforation of the orbitar plate of the frontal bone, i. 436; on the removal of foreign bodies in injuries of the brain, i. 438; on puncturingthe brain in wounds of the dura mater, i. 439; case of chronic inflammation of the dura mater,' i. 440; on puncturing the dura mater to evacuate effused blood, i. 448; on the state of the pulse in concussion, i. 449; cases of loss of memory, &c, after concussion, i. 450 ; on the condition of the alimentary canal and bladder during concussion, i. 450; on the symptoms of laceration of the brain, i. 451; on the condition of the brain in moderate concussion, i. 451; on the causes of concussion, i. 453; case of enormous blood-letting in concussion, i. 453 ; only employs trepanning in injuries of the head when secondary symptoms of irritation and pressure require it, i. 453 ; case of suspended intellect, the conse- quence of an injury to the head, cured by the application of the trephine, i. 460; on wounds of the throat, i. 474; case of fistulous opening in the thyroid cartilage, i. 477; objection to the use of the osce- phagus-tqbe, i. 478; on the signs of wounded lung, i. 483; case of wound of the intercostal muscles by an iron spindle, i. 487; on the danger attending wounds of the lungs, i. 494; on emphysema, i. 495 ; on the treatment of traumatic pneu- monia, i. 498; case of wound of the pericardium, i. 500; mode of practice in small wounds of the intestines, i. 515; on stabs of the liver, i. 525; case of wound of the spleen, i, 526; cases of separation of the spleen from its attach- ments, i. 527; on wounds of joints, and their results, i.536; treatment of wounded joints by a fine suture, i. 538; on the effect of compound fractures on the con- stitution, and the reduction of a compound to a simple fracture, i. 559; on dressing the wound in compound fractures, i. 563; on the union of compound fractures, i. 565; on the question of immediate am- putation, i. 568; considers simple dislo- cation of the spine to be of very rare occurrence, i. 536; says fracture with displacement above the fourth cervical vertebra is immediately fatal, i. 588 ; on softening of the spinal cord after a severe blow, i. 588; on the operation for tre- panning the spine, i. 590 ; on fracture of the anatomical neck of the humerus, i. 606; on fracture of the surgical neck, i. 607; on the union of fracture of the con- dyles of the humerus, i. 610; apparatus for fractured clavicle, i. 614; first de- 810 ANALYTICAL INDEX. scribes fracture of the coronoid process of the ulna, i. 615; on its union by liga- ment, i. 616; on the distinction between fracture of the neck of the femur within and without the capsular ligament, i. 618; on the in-locking of the broken ends of the bone, i.618; on inversion of the foot, i. 619; on interstitial absorption in the neck of the femur, i. 620; admits bony union in fractures external to, but not in fractures internal to, the capsular liga- ment, i. 620; on the treatment of frac- tures of the neck of the femur, i. 624; bandage for the treatment of oblique frac- ture through the trochanter major, i. 626; on the bent position in fracture of the femur, i. 628; apparatus for fracture of the patella, i. 633; on tiie causes of the non-union of fractured bones, ii, 14; on salivary calculi, ii. 150; case of artificial anus in the jejunum terminating fatally, ii. 153; case of fistula in ano, ii. 153; on the impropriety of operating for fistula in phthisical subjects, ii. 164; on dressing the wound after the operation, ii. 167; on the treatment of callous urinary fistula, ii. 177; on the suture of urethral fistula, ii. 178; on urethroplasty, ii. 179; opera- ration for recto-urethral fistula, ii. 186; cases of dislocation from a lax condition of the ligamentous capsules of the joints, ii. 202; on laxity of the ligaments of the lower jaw, ii. 211; on dislocation of the costal cartilages, ii. 216; on the symptoms of dislocation of the sternal end of the clavicle backwards, ii. 217; on a partial dislocation of the humerus, ii. 221; case of reduction of an old dislocation of the elbow, ii. 230; mode of reduction in dis- locations of the elbow, ii, 231; on dislo- cation of the upper end of the radius for- wards, ii. 231; on the difficulty attending the reduction of this dislocation, ii. 232; on the cause of the difficulty experienced in reducing the dislocation of the thumb from the metacarpal bone, ii. 235; on the relative frequency of dislocations of the femur, ii. 236; on the reduction of dis- location of the femur downwards, ii. 241; on dislocation of the semilunar cartilages, ii. 247; cases of dislocation of the great cuneiform bone, ii. 256; case of disloca- tion of the toes, ii. 256; on the double hernial sac, ii. 261; on the nature of strangulation, ii.269; on the complication of strangulated hernia by the presence of an irreducible rupture, ii. 271; case in which the entire hernial sac was ineffec- tually removed, ii. 288; objections to liga- ture of the sac, ii. 288; case of sloughing of the omentum, ii. 301; on the operation of dilating the abdominal ring, the hernial sac not being opened, iiv303 ; reasons io recommending the operation of dividing the stricture without opening the sac, ir large and old ruptures, ii. 303 ; case sloughing of the intestine after it ha been returned into the abdomen, ii. 310; case of tetanus after the operation foi strangulated hernia, ii. 310 ; on encys e hernia of the tunica vaginalis, ii. 321 ; or the seat of femoral rupture, ii. 333 ; oi the presence of other tumours in the fe- moral region, liable to be mistaken foi femoral rupture, ii. 333 ; on the varieties > femoral rupture, ii. 335 ; case of umbili cal rupture, in which the sac was eith absorbed, or burst, ii. 344 ; on the occa- sional enormous size of umbilical rupture in women, ii. 344; on the danger sloughing of the integuments in strangu- lated umbilical rupture, ii. 346 ; on sup- puration of the omentum in strangulated umbilical rupture, ii. 346; case of suc- cessful operation for strangulated umbili- cal rupture during pregnancy, ii. 346: opposed to the radical cure of reducible umbilical rupture by ligature, ii. 347: the operation for strangulated ischiatic rupture, ii. 351; on the operation foi strangulated thyroid rupture, ii. 353 ; < >i pudendal hernia, ii. 355; case of phrenic rupture, depending on malformation the diaphragm, ii. 357; on internal stran gulation, ii. 359 ; case of aneurism mis taken for abscess, ii. 474 ; on the age i which aneurism occurs, ii. 475; on the relative frequency of aneurism in the sexes, ii. 475; cases of several aneurisms in the same person, ii. 476 ; on the effects produced by the ligature on the arteri coats, ii. 493; case in which Brasdor'i operation was performed, ii. 504 ; case o ligature of the common carotid, ii. 508: on the impediment to ligature of the com mon carotid offered by the internal jugu lar vein, ii. 511; on the post-mortem ap pearances in a case in which he had tie*.' the common carotid 13 years previously ii. 512 ; case of aneurism of the posten aural, ii. 515 ; case of ligature of the sub clavian above the clavicle, ii. 518; oi spontaneous aneurism of the brachial, ii 528; on ligature of the arteries of th< fore-arm, ii. 528; case of ligature of th aorta, ii. 528; case of ligature of the e\ ternal iliac in the groin, ii. 531 ; on 1 i«_»•» ture of the external iliac, ii. 539 ; on th< post-mortem appearances after ligature o the external iliac, ii. 540 ; case of antu rism of the anterior tibial, ii. 543; oi the treatment of aneurism of the anterio tibial low down in the leg, by openinj the sac, and tying the artery above ani ANALYTICAL INDEX. 811 below, ii. 544 ; on the post-mortem ap- pearances after ligature of the femoral, ii, 545; on the treatment of aneurismal va- rix, ii. 550; on the causes of varicocele, ii. 576 ; operation for varicocele, ii. 577; on the excision of piles, ii. 586; case of stricture of the oesophagus ulcerating ex- ternally, iii. 30; case of stricture of the oesophagus in which a false passage was made through into the anterior mediasti- num, iii. 32; case of stricture of the rectum, iii. 44 ; on the passing a bougie in stric- ture of the urethra, iii. 71; on the use of metallic bougies, iii. 71; on haemorrhage from the urethra after passing the bougie, iii. 77 ; on the practice to be adopted when a laceration of the urethra by bougie is suspected,iii. 77 ; on the use of the armed bougie, iii. 84; case of a ball lodged in the frontal sinus, iii. 94 ; case of fish-bone at the glottis, iii. 98 ; on chronic enlargement of the prostate, iii, 139 ; on the symptoms and post-mortem appearances of chronic enlargement of the prostate, iii. 140; on the characters of enlarged prostate, iii. 140; on the treat- ment of enlarged prostate, iii, 142; on the treatment of retention of urine from en- larged prostate, and on catheterism in such cases, iii. 143 ; case of haematocele, iii. 177 ; case of haematocele of 17 years duration, iii. 177 ; on puncturing in spina bifida, iii. 189 ; on tapping in the linea alba, iii. 205; case of spontaneous rupture of the ovarian cyst, iii. 214 ; case of ova- rian dropsy iri which the fluid was dis- charged by ulceration of the navel, iii. 215 ; case of hour-glass hydrocele, iii. 221 ; on the situation of the testicle in hy- drocele, iii. 221 ; on the characters of the serum in hydrocele, iii. 221 ; on the spon- taneous cure of hydrocele, iii. 223; on the radical cure of hydrocele by exercise after tapping, iii. 225; on the cause of the failure of injection to cure the disease, iii. 228 ; cases of foreign bodies the nuclei of stones, iii. 249 ; case of renal calculus, iii. 267 ; case of renal calculus communi- cating with abscess in the loins, iii. 268 ; case of suppuration of the kidney from impaction of calculus in the ureter, iii. 270; on the treatment of calculi in the ureters, iii. 270; case of large calculus, iii. 273 ; case of a great number of calculi in the bladder, iii. 273; on the dilatation of the female urethra, iii. 284 ; case of an old man operated on for stone, iii. 297; on the section of the prostate, iii. 320 ; on opening the membranous part of the ; urethra, iii. 321; on the symptoms of stone in women, iii. 349; case of ulcera- tion of the bladder and vagina by the pressure of a large stone, iii. 349 ; on the incontinence of urine consequent on litho- tomy in women, iii. 353 ; case of prostatic stone, iii. 368 ; case in which lithectasy was performed, iii. 375; case of enlarge- ment' of the nymphae, iii. 400; case of human horns, iii. 403; case of very large fatty tumour, iii. 428 ; opinion that fatty tumours sometimes take on a malignant degeneration, iii. 429 ; on cellular hyda- tids of the breast, iii. 432 ; on sebaceous tumours, iii. 434 ; on the cause of seba- ceous tumours, iii. 434; case of cellular membranous tumour, iii. 449 ; on medul- lary fungus of bone, iii. 457 ; case of tu- mour in the popliteal nerve, iii. 506; on tumours on nerves in stumps, iii. 506; on fungous degeneration of the nipple of the breast, iii. 528; on the development of the nipple in the foetus, and its subse- quent changes, iii. 528; on hydatid swell- ings of the breast, iii. 534 ; on the symp- toms and treatment of cellulous hydatids of the breast, iii. 534 ; on polypoid hyda- tids of the breast, iii. 535 ; on globular hydatids of the breast, iii. 535; on the question as to the propriety of removing a scirrhous breast, iii. 539 ; on the nature of the cysts in cystic swelling of the testicle, iii. 553; on the retraction of the cord during the extirpation of the testicle, iii. 557; cases of chimney-sweep's cancer in the cheek, iii. 560; case of excision of a portion of the radial nerve, iii. 636 ; mode of amputating at the shoulder-joint with a single flap, iii. 713; case of am- putation at the shoulder joint, iii. 718 ; mode of extirpating the metacarpal bones of the middle and ring fingers, iii. 722; case of excision of part of the hand, iii. 722; opinion in favour of immediate am- putation in severe injuries of the lower extremities, the constitution then having only one shock to sustain, iii. 725; case of excision of the lower jaw, iii. 747. Cooper's, Mr. Bransry, case of reduction of an old dislocation of the elbow, ii. 231; on dislocation of the upper end of the radius forwards, ii. 232; on the double hernial sac, ii. 261 ; case of reduction en masse, ii. 275 ; case in which Gerdy's operation for the radical cure of rupture was performed, ii. 284; case of simple serous cysts of the neck, iii. 432; case ot entrance of air into a vein, iii. 604. % Cooper's, Mr. Samuel, case of orchitis simulating strangulated rupture, i. 202 ; mentions Mr Ramsden's case of lumbar abscess, i. 209; on the substance which fills up the acetabulum in secondary dis- location in hip disease, i. 287 ; on secon- dary haemorrhage in gun-shot wounds, i. 812 ANALYTICAL INDEX. 377; case of chronic tetanus of five weeks' duration, i. 417 ; on the causes . of tetanus, i. 418 ; cases of prolapsed womb in virgins, ii. 373; on the effects of compression in aneurism, ii. 488. Cooper's, Mr. William, case of radial aneurism, ii. 528. CoPELANn's, Mr., objection to stuffing the rectum in casesof haemorrhage after the operation for rectal fistula, ii. 168; Opera* tion for recto-vaginal fistula by the divi- sion of the sphincter ani, ii. 199; on pro- lapse of the internal membrane of the rectum, ii. 398; on the diagnosis between prolapsed rectum and haemorrhoids, and intus-susception, ii. 399; operation for prolapse of the rectum, ii. 403; on the removal of internal piles by ligature, ii. 584; on the application of the ligature, ii. 585; on the incisionof the stricture in stricture of the rectum, iii. 51; case of very large fatty tumour, iii. 428. Copland, Dr., on the asthenic boil, i. 152; on anthrax, i. 155 ; diagnostic sign for vertebral caries, i. 312; on puncturing the brain in chronic hydrocephalus, iii. 188; on the age at which bronchocele most usually occurs, iii. 389. Coracoid process, fracture of i. 601. CornSjdii. 402. Cornuau's, M., mode of amputating at the hip-joint, iii. 698; at the knee with the cir- cular cut, iii. 700; at the shoulder-joint with the circular cut, iii. 715; mode of operating in exarticulation of the fore-arm at the elbow, iii. 719. Cortez, M., on the treatment of haemor- rhage consecutive on the extraction of a tooth, ii. 143. Cotton's, Dr., case of injurious effects pro- duced by inhalation of ether, iii. 769. Coulson's, Mr. case of hysterical affection of the joints, i. 278; on the symptoms of this disorder, i. 278 ; explanation of the pain on the inside of the knee in hip disease, i.-280; on the bursting of ab- scesses of the hip-joint, i. 282; on dislo- cation into the foramen ovale in hip dis- ease, i. 287; on the diagnosis between hip disease in the third stage, and psoas ab- scess, i. 289; on salt water bathing in hip disease, i. 292; case of closure of the rectum from the presence of a foreign body, iii. 108. Coxalgia, inflammation of the hip-joint, i. 278 ; the three stages of the disease, i. 278; symptoms of acute inflamma- tion of the hip-joint, i. 279 ; Key on the greater frequency of chronic than of acute inflammation of the hip-joint, i. 279; symptoms when suppuration takes place, i. 279; symptoms of the first stage of chronic inflammation of the hip-joint, i. 279 ; Brodie on ulceration of the carti- lage, the primary affection in diseased hip, i. 280; Key's opinion that the ulcera- tion of the cartilages is preceded by inflammation of the ligamentum teres, i. 280 ; South on the pain on the inside of the knee in hip disease, i. 280; Bell and Coulson's explanation of that symptom, i. 280 ; symptoms of the second stages of chronic inflammation of the hip-joint, i. 280; Astley Cooper on the second stage of hip disease, i. 280; Key on the symp- toms which indicate the special part of the joint affected, i. 281; symptoms of the third stage, i. 281; Fricke's method of examining the length of the limb during the progress of the disease, i. 281; Astley Cooper and Coulson on the bursting of abscesses of the hip-joint, i. 282; Dr. Mackenzie and Scott's cases of abseesses of the hip joint, i. 282; Brodie on the difference between hip disease from ulcer- ation of the cartilage, and that from scro- fulous deposit in the cancellous structures of the bones, i. 283; shortening and lengthening of the diseased limb, i. 284; Hunter on these symptoms,i. 284; Cline and Lawrence on these symptoms, i. 284; theshortening only apparent, i. 284; Rust and Fricke's explanation incorrect, i. 284; South on the shortening of the limb, i. 284; the lengthening of the limb may be either seeming or real, i. 285; explanation of the lengthening of the limb by Petit, Camper, Valselva, Monro, Van der Haar, de Haen, Vermandois, Schwenke, Calli- sen, Plenck, Portal, Ficker, Duverney, Clossius, Boyer, Falconer, Rust, Lan- genbeck, Richter, Schreger, Larrey, Che- lius, Fricke, Brodie, and Crowther, i. 285 ; Weber's experiments show that the head of the thigh-bone is retained in the socket by atmospheric pressure, i. 285; these experiments of great importance in reference to diseases of the hip-joint, i. 286; South's explanation of the length- ening of the limb, i. 286; Astley Cooper on the lengthening of the limb from ef- fusion into the joint, i. 286; Lawrence on the lengthening of the limb, i. 286; dislocation of the head of the thigh-bone, i. 287 ; Nester, Van der Haar, Berdot, Schreger, and Textor on the dislocation of the head of the thigh-bone downwards and inwards, i. 287; Hoffman's case of separation of the head of the femur, and its removal by the surgeon, i. 287; South on the appearances after death in hip disease, i. 287 ; Earle on dislocation into the ischiatic notch, i. 287; Boyer, Brodie, and Coulson on dislocation into the fora- ANALYTICAL INDEX. 813 men ovale, i. 287; Ducros, jun. on dislo- cation forwards on the share-bone, i. 287 ; the formation of a new socket, i. 287; Samuel Cooper on the substance which fills up the acetabulum i. 287 ; diagnosis of coxalgia from congenital luxation of the thigh, shortening of the extremity from recession and twisting of the hip- bone, nervous sciatica, and malum coxae senile, i. 288; coxalgia cannot well be confounded with phlegmasia alba dolens, psoas abscess, or primitive dislocation of the thigh, i. 288 ; may be confounded with fracture of the neck of the thigh- bone under certain circumstances, i. 2^8; Bell on the pain in hip disease, i. 288 ; South on the sympathetic pain in the hip from disordered bowels, i. 289 ; South, Smith, Wemherr, Astley Cooper, and Charles Bell on the morbus coxae senilis, i. 289; Coulson on the diagnosis between hip disease in the third stage, and psoas abscess, i. 289; post-mortem appearances, i. 290; post-mortem appearances in William Adams' case, i. 290; etiology of hip-joint disease, i. 291 ; Fricke on the distinction between coxalgy and cox- arthrocacy, i. 291; prognosis always un- favourable, i. 291; treatment, i. 291; in the first stage of acute coxalgia, i. 291 ; treatment of chronic coxalgia, i. 292; Nicolai and Klein recommend the use of the apparatus for fractured neck of the femur, i. 292; Physick on the treatment of coxalgia, i. 292; Scott's plan oftreat- ment, i. 293; Lawrence's observations on the plan of treatment advocated by Scott, i. 293; has been employed by Fricke with advantage, i. 294; treatment of the second stage, i. 294; application of the actual cautery, i. 294; Rust objects to the use of issues, i. 294 ; approved of by South, i. 294; the actual cautery or burning cylinders preferable in all cases where the limb is much lengthened, the muscles relaxed, and where there is great swelling from collection of fluid, i. 294; Volpi has not found benefit from the actual cautery, when the first symptoms of disease oc- curred in the knee, and not at the hip- joint, i. 294 ; Brodie on the influence of the primary irritation of the issue, and on the maintaining it by repeated appli- cations of caustic potash or sulphate of copper, i. 295; approved of by South, i. 295; Duval's local steam-bathing appa- ratus, i. 295 ; Brodie on the use of a seton in the groin, i. 295 ; results of the treat- ment, and management of convalescence, i. 296; Rust and Brodie on warm bathing, i. 296; Fritz, Rust, and Jaeger on the mercurial treatment, i. 296; Brodie on Vol hi.—69 the importance of rest and position, i. 296; general treatment in the first two stages of coxalgy, i. 297 ; Jaeger, Rust, Dieffen- bach, and Frank on the general treatment of coxalgy, i. 297; Fricke's plan, i. 297; treatment of the consecutive dislocation, U297; reduction of the dislocation fre- quently not successful, i. 297; views of Petit, Callisen, and Jaeger on the reduc- tion of consecutive dislocation, i. 297 ; cases by Berdot, Hagen, Ficker, Thile- nius, Mozilewsky, Schneider, B. Heine, F. Humbert, M. N. Jacquier, Textor, Volpi, Schreger, von Winter, Harless, Fricke, and J. Hein, i. 297, 298; treat- ment of suppuration, i. 298; the abscesses to be freely opened, i. 298 ; Ford, Wend, Van der Haar, Rust, Brodie, and Jaeger on the treatment of these abscesses, i. 298; Sabatier and Ficker advise their being opened with caustic, i» 298; Larrey, with the red-hot trocar, i. 298 ; Rust, with the actual cautery, i. 298 ; Rust advises pass- ing a seton through the joint, i. 298; Brodie and Jaeger recommend free inci- sions in opening these abscesses, i. 299; Brodie and South on the management of abscesses at the hip, i. 299 ; subsequent treatment, i. 299 ; resection of the carious head of the thigh-bone, i. 299 ; excision of the head of the femur recommended by Jaeger, Kirkland, Richter, and Ver- mandois, i. 299 ; performed by White and Hewson, i. 299 ; Kerr and Baffos exarti- culated the thigh-bone, i. 299; Charles Bell's proposition, i. 299; Barry's case of accidental reduction of the dislocation, i. 299. Coxe, Mr., on the treatment of vesico- vaginal fistula, by drawing off the urine, and by compression, ii. 189. Coze, M., on twisting round of the patella, ii. 246. Cramer's, M., treatment of fistulous pas- sages, i. 108. Crampton's Sir Philip, experiments on the ligature of arteries, i. 335; on Com- pression in the treatment of aneurism, ii. 486 ; case of aneurism in which the tem- porary ligature was employed, ii. 496; operation for ligature oF the common iliac, ii. 533; on the application of leeches to mucous surfaces, hi. 613 ; on the exci- sion of joints, iii. 728 ; recommends the non-division of the ulnar nerve in exci- sion of the elbow-joint, iii. 733 ; case of excision of the elbow-joint, iii. 734. Crisp's, Mr., case of a piece of broken catheter in the bladder, iii. 135; case of fracture of a renal calculus by sudden exertions, iii. 368. 814 ANALYTICAL INDEX. Croix, M. La, d'Orlean's, case of ampu- tion at the hip-joint, iii. 689. Croserio's, M., modification of the opera- tion for salivary fistula, ii. 149. Crosse, Mr., on the characters of the re- spective varieties of inversion of the womb, ii. 382 ; on the successive steps of the inventing process, ii. 383; on the concavity formed in all cases of inversion, ii. 383 ; on polypus-of the fundus uteri as a cause of inversion, ii. 384 ; on the pre- sence of coagulated blood, hydatids, and moles in the womb,as causes of inversion, ii. 385; on the spontaneous breaking up of calculi in the bladder, iii. 275. Crowther, Mr., on tapping lumbar or psoas abscess with a trocar, i. 212,; on the lengthening of the limb in hip disease, i. 285. j Cruveilhskr, M., on phlebitis, i..92; dis- tinctly of opinion that cartilages are de- void of vascularity, i. 253 ; case of bony anchylosis of the right condyle of the lower jaw, i. 274 ; apparatus for fractured clavicle, i. 603; on the production of callus, i. 621 ; on the causes of congenital dislocation, ii. 208; on the contents of the sac formed by the prolapsed vagina, ii. 371; on incontinence of urine in prolapse of the womb, ii. 372; on the! altered form and direction of the os uteri in prolapse of that organ, ii. 372; on the elongation of the womb in prolapse, ii. 372; on the formation of calculi in the displaced bladder consequent on pro- lapsus uteri, ii. 372 ; on displacement of the rectum consecutive to prolapse, ii. 373; on excision of the prolapsed scir- rhous womb, ii. 381; on the causes of club-foot, ii. 446; case of opening of the rectum under the glans penis, iii. 38; on encysted swellings, iii. 180. Cuillvier, M., on the solution of the chlo- ride of lime in the treatment of foul, gan- grenous, or torpid ulcers, ii. 44. Cullen, Dr., on the proximate cause of in- flammation, i. 38. Cullen, Mr. Peter, on the treatment of' haemorrhage consecutive on the extrac-; tion of a tooth, ii, 143. I Cumming's Dr., description of cancrum oris, i. 76. Cuming's, Mr., case of resection of the cla- vicle, iii. 763. Cunningham's, Dr., case of compound frac- ture of the skull, and lodgment of the breech of a pistol within the cranium, i. 434. Cupping, iii. 615. Curling, Mr., on the effects of the scorpion sting, i. 387; on the proximate cause of tetanus, i. 417; on haematocele of the spermatic cord, iii. 178. Curvatures:—definition, ii. 417; causes, ii* 417 ; condition of the muscles in curva- tures, ii. 418; Guerin on the condition of the muscles in curvatures, ii. 419; disease of the bones as causes of curvature, ii. 419; prognosis, ii, 419; treatment, ii. 419; subcutaneous division of the muscles, or their tendons or aponeuroses, when the muscles are contracted and changed in their tissue, ii. 420; wry neck, ii. 421; definition and causes, ii. 421; Stromeyer and Dieffenbach on the causes of wry neck, ii. 422 ; Syme's case, ii. 422; Bro- die's case of wry neck alternating with insanity, ii. 422; Syme on the distorted position of the head caused by caries be- tween the occiput and atlas, as liable to be mistaken for wry neck from muscular contraction, ii. 423; prognosis, ii. 423 ; treatment, ii. 423; Jorg's apparatus for keeping the head straight, ii. 423 ; divi- sion of the sterno-cleido-mastoideus, ii. 424; its subcutaneous section, ii. 424; mode of performingthe operation, ii. 424; section of other muscles sometimes requi- site, ii. 425; after-treatment, ii. 425,; Stromeyer on the after-treatment, ii. 425; spasm of the sterno-cleido-mastoideus a cause of wry neck, ii. 425; Gooch's case of spasm of the platysma myoides cured by operation, ii. 426; treatment of wry neck caused by large scars, ii. 426; their entire extirpation requisite, ii. 426; wry neck from curvature of the cervical ver- tebrae, unaccompanied by anchylosis, ii. 426; curvatures of the spine, ii. 427; di- rections of the spinal curvatures, ii. 427; Meckel, Jorg, and Choulart on the influ- ence of spinal curvature on the transverse diameter of the pelvis, ii. 427; inclination of the spinal column to one side, ii. 428; high shoulder, ii. 428; South on the causes of high shoulder, ii. 428; general symptoms attending lateral inclination of the spine, ii. 429; posterior curvature of the spine, cyphosis, ii. 429; symptoms, ii. 429; inclination if the spine forwards, ii. 429; occasional causes of spinal cur- vature, ii. 429; Stromeyer on palsy of the serratus magnus as a cause of scoliosis or lateral curvature, ii. 430; Gunther on the condition of the muscles in snake-like scoliosis, ii. 430; Zink on the. situation and direction of scoliosis, ii. 430 ; Syme on wry neck as a cause of lateral curva- ture, ii. 431; diagnosis, ii. 431; Delpech on the swelling of the fibrous inter-carti- lage as a cause of spinal curvature, ii. 431; symptoms and progress, ii. 432; curvature of the spine from softening of the bones, ii. 432; prognosis, ii. 433; South condemns the practice of lifting by the head, ii. 434; treatment of spinal cur- ANALYTICAL INDEX. 815 vature, ii. 434 ; application of apparatus acting by pressure, ii. 434; apparatus ope- rating by extension, ii. 434 ; apparatus acting by extension and pressure, ii. 435; the latter only can act efficiently, ii. 435; use of gymnastics with the extending ap- paratus, ii. 437; effects of gymnastics, ii. 437; treatment when the cause of the curvature is an unequal contraction of the muscles, ii. 438; Guerin on the section of the contracted muscles, ii. 439; Robert Hunter and Syme on the section of muscles in spinal curvature, ii. 439; internal treatment in curvatures depend- ent on great muscular weakness, ii. 440; treatment of high shoulder, ii. 440; of curvature of the spine depending on soften- ing and thickening of the fibrous inter- cartilage, ii. 440 ; on rickets, ii. 441; on rheumatism, ii. 441; curvatures of the spine from contraction of one side of the chest, incurable, ii. 441; from shortening of one of the lower limbs, ii. 441; curva- tures of the limbs, ii. 441; nature and causes, ii. 441; curvatures of the lower limbs, ii. 442; more frequent than those of the upper, ii. 442; curvatures of ihe hip, ii. 442; causes, ii. 442; treatment, ii. 442; Stromeyer's case in which the section of the pectineus and sartorius was practised, ii. 442; curvatures of the knee, ii. 443; causes, ii. 443; to be distinguished from the curvature of anchylosis, ii. 443 ; in- knee, ii. 443; characters, ii. 443; treatment, ii. 443; curvature of the knee outwards, ii. 443; of rare occurrence, ii. 443; curva- ture of the knee forwards, ii. 443 ; causes, ii. 443; treatment, ii. 444; section of the hamstring tendons, ii. 444; objections to the operation, ii. 444; performance of the operation, ii. 444; Fergusson on disloca- tion of the knee after the division of the hamstring tendons, requiring amputation, ii. 444; Stanley's case of contracted knees, cured by the subcutaneous section of the) hamstring tendons, ii. 441; curvature of the feet, ii. 445; varieties of curvature, ii. 445; club-foot, ii. 445; characters, ii. 445; various degrees of club-foot, ii. 446; causes, ii. 446; condition of the parts en- gaged in the club-foot, ii. 446; Pare, Du- verney, Scarpa, Bruchner, Naumberg, Wantzel, Delpech, Rudolphi, Camper, Glisson, Cruveilhier, Martin, Scoutetten, Duval, and Blasius on the causes of club- foot, ii. 446, 447; Little on the diagnosis between club-footand the deformity of the tarsus caused by rickets ii. 447; South's case of hysterical club-foot, ii.447;South's case of club-foot from palsy of the mus- cles of the leg, ii. 449; prognosis, ii. 450; treatment, ii. 450; indications oftreat- ment, ii. 450; South on the treatment of club-foot in early infancy,ii.451 ; Scarpa's machine for club-foot, ii. 451; South on the application of Scarpa's shoe, ii. 452 ; subcutaneous division of the tendons, ii. 452 ; division of the tendo Achillis, ii. 452; Thilenius, Michaelis, Sartorius,Del- pech, Stromeyer,Stoess, Bouvier, Guerin, Scoutetten, Dieffenbach, and South on the section of the tendo Achillis, ii, 453; treat- ment of the foot after the division of the tendon, ii. 453; application of the extend- ing power after the wound has healed, ii. 453; South on the application of the ex- tending power,after the performance of the operation, and the healing of the wound, ii. 454; division of the plantar fascia, ii. 455; of the tendons of tibialis anticus and extensor proprius pollicis, ii. 455; of the tibialis posticus, flexor pollicis longus, flexor pollicis brevis,and adductor pollicis, ii. 455; South on the division of the plantar fascia, ii. 455; South on the divi- sion of the tendon of the tibialis posticus, and on the danger of wounding ihe poste- rior tibial artery during the operation, ii. 455; after-treatment, ii. 455; Blasius' opinion against tenotomy in club-foot, ii. 456; splay-foot, ii. 456; characters, ii. 456; inconveniences of splay-foot, ii. 456; distinguished from broad-foot, ii. 457; causes, ii. 457; Liston, Froriep, Rognetta, Thune, and Stromeyer on the causes of splay-foot, ii. 457; Thune on primitive and secondary valgus, ii. 457 ; treatment, ii. 458; Held on the division of the peronei muscles in splay-foot, ii. 458; South on the cause of mischief in splay-foot, ii. 459; horse-foot, ii. 459; characters, ii. 459; causes, ii. 459; treatment, ii. 459; Jflrg's apparatus, ii. 460 ; South on ulceration of the calf as a cause of horse-foot, ii. 460; South's case of horse-foot from palsy, ii. 460; South's apparatus for horse-foot, ii. 461 ; hook-foot, ii. 461; characters, ii. 461; treatment, ii. 461; Tyrrell's case of hook-foot, arising from an accident, ii. 461; curvature of the upper limbs, ii. 462 ; curvatures of the shoulder, ii. 462 ; of rare occurrence, ii. 462 ; symptoms and treat- ment, ii. 462 ; curvatures of the elbow, ii. 463 ; except when depending on anchy- losis or inflammatory deposit in the soft parts about the joint, caused by contrac- tion of the biceps and brachialis anticus, ii. 463; treatment, ii. 463; division of the tendon of the biceps, ii. 463; curvatures of the hand, ii. 463 ; causes and charac- ters, ii. 463; permanent bending of the hand, ii. 463 ; characters, ii. 463; Lode on two kinds of curvature of the hand, ii. 463; causes and treatment, ii. 463 ; permanent 816 ANALYTICAL INDEX. straightening of the hand, ii. 464 ; of rare occurrence, ii. 464; characters, ii. 464 ; permanent bending of the fingers, ii. 464 ; causes, ii. 464; diagnosis, ii. 464 ; curva- ture caused by contraction of the palmar fascia, ii. 464; characters, ii. 464; Goy- raud and Sanson on the retraction of the tendons, ii. 465; signs of the curvature when caused by contraction of the flexor muscles, ii. 465; by a cicatrix, ii. 466; by palsy, or section of the extensor ten- dons, ii. 466; by anchylosis, ii. 466; divi- sion of the palmar fascia, ii. 466; treatment of curvature from a cicatrix, ii, 466; curva- tures of bones and their treatment, ii. 466. Custance's, Mr., case of blacking pot in the rectum, iii. 108. Cusack's, Mr., mode of operating in exci- sion of the lower jaiw with the condyles, iii. 750; on the nonnecessity for tying the carotid artery, prior to excision of the lower-jaw, iii. 752 ; cases of exarticula- tion of the lower-jaw, iii. 752. Cyphosis, ii. 429. Cystectasy, iii. 375. Cysticercus cellulosa, iii. 441. Dahl's, M., artery-compressor, i. 331. Dailliez, M., on strangulation of intestine in the concavity formed by the inverted womb, ii. 385. Dallam, Mr., on the use of raw cotton in the treatment of burns, i. 131. Dalrymple, Mr., on the treatment of branching aneurism, ii. 554; case of ossified encysted tumour of the eyelid, iii. 436; on the nature and characters of tumours of the nose; iii. 598. Davat's, M., operation for varicocele, ii. 578. Davenport's, Mr., case of consecutive he- morrhage after the extraction of a tooth, ii. 141. David's, M., case of excision of a joint, iii. 726. Davidson, Mr., successful operation for lacerated perineum, ii. 39; case of arti- ficial retention of the faeces for several days after the operation, ii. 40. Davie's, Mr., operation for removing the dislocated sternal end of the clavicle, ii 219 : case of excision of a joint, iii..726 Davies, Dr., on the operation for empyema, iii. 206. Deadrick's, Dr., case of .excision of part of the side of the lower-jaw without the condyle, iii. 748. Dease, Mr., refers, tire-principal cause of disease in injuriesof the skull, not to in- flammation and suppuration of the dura mater, hut to. injury of the pia mater and brain, i. 424; on the cases in which the cranium is laid bare, contused, or its tables simply divided, i. 425; rules for the application of the trephine, i. 426; on puncturing the dura mater, when pus is not found between it and the bone, i. 426; objection to the use of the trephine in simple fraetures, i. 433; only employs the trepan when secondary symptoms of irritation and pressure require it, i. 454; casein which the temporary ligature was employed, ii. 496. Decker's, Mr., on tapping lumbar or psoas abscess with a trocar, i. 212. Delpech's, M., cases of malignant pustule, i. 79 ; commendation of cubebsin gonor- rhoea, i. 196; has shown that cubebs do not cause inflammation of the testicles, i. 197; treatment of gonorrhoea, i. 197; on the after-management of ligatures on arteries, i. 338; denies the possibility of simple dislocation of the spine, i. 586; apparatus for fractured clavicle, i. 603; on the in-locking of the broken ends of the bone in fracture of the neck of the femur, i, 618 ; on the rotation of the foot out- wards, i. 618; on inversion of the foot, i. 619; on frictions with the ung. hydrarg. cin. in primary syphilis, ii. 81; on the dis- eased condition of bones in syphilis, not caries, but necrosis, ii. 116; enterotome, and operation for artificial anus, ii. 158; on urethroplasty, ii. 179; on the swelling of the fibrous inter-cartilage as a cause of spinal curvature, ii. 432; on the causes of club-foot, ii. 446; on the section of the tendo Achillis in club-foot, ii. 453; on ligature of the external iliac, ii. 538; on the ligature of the spermatic veins in varicocele, ii. 578; mode of extirpating piles, ii. 583; objections to gastrotomy or entorotomy, iii. 105; case of sarcomatous enlargement of the scrotum, iii. 449; on extirpation of the womb, iii. 572; modifi- cation of the Indian method of rhinoplasty, iii. 583; case of division of the ulnar nerve, iii. 636; case of division of the posterior tibial nerve, iii. 636; mode of amputating at the hip-joint with the flap out with a single flap, iii. 691. Demme's, M., apparatus for ligaturing com- plete rectal fistulae, ii. 169. Denan's, M., practice in wounded intestine, i. 509. Deneux's, M., case of wound of the womb, i. 533. Desault,-M., on the treatment of in-grow- ing of a nail, i, 223; artery-compressor, i.,331; only employs the trepan in injuries of the head when secondary symptoms of irritation and pressure require it, i. 454; on the stanching the bleeding from a wounded intercostal artery, i. 492; band- ANALYTICAL INDEX. 817 age for rupture of the tendo Achillis, 1 541; case of simple dislocation of the spine, i. 586; apparatus for fractured clavicle, i. 604; treatment of fractured olecranon, i. 614; on the in-locking of the broken ends of the bone in fracture of the neck of the femur, i. 618; on the rotation of the foot outwards, i. 618; ap- paratus for fracture of the neck of the femur, i. 623; on permanent extension in fracture of the femur, i. 628; on the treat- ment of salivary fistula, ii. 147; on the treatment of fistula of the parotid duct, ii. 149; on the treatment of artificial anus, ii. 158; apparatus for ligaturing complete rectal fistulae, ii. 169; on the treatment of recto-urethral and recto-vesical fistula, ii. 185; on the treatment of vesico-vaginal fistula by drawing off the urine and by compression, ii. 189; on the primitive direction of dislocation of the humerus, ii. 221; on the surgical treatment of dis- location of the thumb from the metacarpal bone, ii. 235; on the spontaneous cure of umbilical rupture, ii. 346; fatal operation for the radical cure of umbilical rupture by ligature, ii. 347; case in which he performed Anel's operation for aneurism, ii. 488; mode of operating in ovarian dropsy, iii. 209 ; mode of treating con- genital hydrocele, iii. 232; mode of am- putating by the circular incision, iii. 640; mode of amputating at the shoulder- joint, iii. 714. Deschamps', M,, case of displacement of the heart, ii. 361; case in which Brasdor's operation was performed, ii. 504. Deuber, M., on the application of sutures in vesico-vaginal fistula, ii. 193. Dewar's, Mr. H., treatment of fistulous passages, f. 357. Diathesis purulenta, i. 57. Dick, Professor, on the nature of the disease in hydrophobia, i. 40.5. Dickin's, Mr., case of foreign body in the bronchus, in which tracheotomy was perT formed, and the foreign body extracted with the forceps, iii. 118. Diday, M., on the seat of strangulation in rupture ii. 268. Dieffenbach, M., on the general treatment of coxalgy, i. 297; on the torsion of arte- ries, i. 341; torsion-forceps, i. 342; ob- jections to torsion, i. 344; thin insect C pins, and the twisted suture, i. 361; on the sutures in the operation for hare-lip, ii. 25; on the removal of the edges of the cleft.in staphyloraphy, ii. 31; mode of uniting the cleft, ii. 32; operation when the cleft is very large and complicated, ii. 33; on the after-treatment, ii. 34; mode of closing the fissure which sometimes s 69' remains after the operation, ii. 35; on the operation for the treatment of lacerated perineum, ii. 40; on the application of the sutures, ii. 40; on the artificial re- tention of the faeces for several days after the operation, ii. 40; cure of artificial anus from a lance-wound by the actual cautery, ii. 161; on the treatment of cal- lous urinary fistula, ii. 177; on the suture of urethral fistula, ii. 178 ; on the intro- duction of the running stitch, ii. 178; on urethroplasty, ii.. 179; on the operation of urethroplasty in fistulas near the scrotum, ii. 179; in large fistulas in the middle or fore-part of the penis, ii. 179; in fistulas elose behind the prepuce, ii. 180; in large openings immediately behind the glans, with deficient prepuce, ii. 180 ; on cau- terization as a means of cure in vesico- vaginal fistula, ii. 190; mode of applying sutures in vesico-vaginal fistula, ii. 193 ; on the after-treatment, ii. 194; treat- ment of large vesico-vaginal fistulae by drawing the mucous membrane together, ii. 196; treatment of moderately large fistula with a projecting fold of the bladder, ii. 197; case of old dislocation of, the humerus, to reduce which the ten- dons of several muscles were divided, ii. 226; on the use of the actual cautery in prolapsus uteri, ii. 379; on the causes of wry-neck, ii. 422; on section of the tendo Achillis in club-foot, ii. 453 ; ope- ration for considerable narrowing of the mouth, iii. 25; operation to remedy the opening of the rectum into the vagina, iii. 36; operation of chiloplasty, iii. 517; modification or the Indian method of rhinoplasty, iii. 584; operation for defects of the wings of the nose, iii. 587; modi- fication of the operation for sunken nose, iii. 587; operation for raising a sunken nose, iii. 590 ; operation for dropping in of the bridge of the nose, from the de- struction of part of the septum, iii. 592 ; operation to remedy the turning down- wards of the tip of the nose, iii. 592; ope- ration for the subcutaneous division of the nerves of the cheek, iii. 634 ; case of exarticulation of metatarsal bones, with the diseased bones of the tarsus, iii.. 710; mode of operating in extirpation of the superior maxillary bone, iii. 755. ietrich, M., on ligature of the common carotid, ii. 509; on ligature of the ex- ternal carotid, ii. 512 ; of the lingual artery, ii. 513; of the external maxillary or facial, ii. 514 ; on the operation for the ligature of the subclavian on the tracheal side of the scalenus, ii. 520; on ligature of the innominata, ii. 522; of the verte- bral artery, ii. 526. 818 ANALYTICAL INDEX. Dionis' artery-compressor, i. 331; on in- cision of the hernial sac and the intro- duction of the lint-tents for its radical cure, ii. 283; on amputation just above the ankle, iii. 674. Dislocations :—definition, ii. 200; various kinds of dislocations, ii. 200 ; various de- grees of distortion, ii. 201 ; diagnosis, ii. 201; South on the diagnosis of disloca- tions, ii. 201 ; occasional causes, ii. 201; South and Lawrence on dislocations from muscular action, ii. 202; Astley Cooper's cases of dislocation from a lax condition of the ligamentous capsules of the joints, ii. 202;Travers, jun.'s case of dislocationinto the ischiatic notch in a boy five years old ii. 202 ; Malgaigne on the frequency of dis- location in the different joints, ii. 202 ; laceration of the ligaments, etc., in com- plete dislocations, ii. 202 ; formation of a ne w j oi n t in ol d d isl ocations, ii. 203; prog- nosis, ii. 203; reduction of the dislocated bone more or less difficult according to the circumstances of the case, ii. 203 ; Liston's case of speedy reduction of a dis- located femur, ii. 203 ; South on the re- duction of dislocations, ii. 203; treatment of dislocations, ii. 204; reduction of the dislocated bone by extension and counter- extension, ii. 204; South on the reduction of old dislocations, and on the necessity of caution in practising extension, ii. 204 ; Cline jun.'s case of reduction of an old dislocation of the h umerus, ii. 204; obsta- cles which render the reduction difficult or impossible, ii. 205 ; treatment of old dislocations, ii. 205; obstacles to the re- duction of old dislocations, ii. 205; South, Smith, Dupuytren, and Breschet on the reduction of old dislocations, ii. 205,206; remedies to reduce the muscular power, ii. 20G; after-treatment, ii. 206; South on ;the recurrence of dislocation after reduc- tion, from exhaustion of the muscular power, ii. 206 ; treatment of sprains, ii. 206 ; South on the auxiliary treatment in reducing dislocations, ii. 206,207, i com- pound dislocations, ii. 207 ; treatment, ii. 207; removal of the head of the bone in compound dislocation, when it cannot be reduced, ii. 207; treatment of dislocation attended with fracture,ii. 207; congenita! dislocations, ii. 207; Hippocrates, Avi- cenna, Pare,Palletta,Sandefort, Schreger, and Dupuytren on congenital dislocation of the hip, ii. 207; Schreger, Dupuytren, Breschet, E. Stromeyer, D'Outrepont, Cruveilhier, von Ammon,, and Guerin on the causes of congenital dislocations, ii. 208; post-mortem appearances, ii. 208; causes of congenital dislocations, ii. 208 ; possibility ofreduction, ii. 209; dislocation of the lower jaw, ii. 209; symptoms and direction, ii.210;causes,ii. 210; reduction, ii. 210; South on the reduction of this dis- location, ii. 210; after-treatment, ii. 210; sub-taxation of the lower jaw, ii. 210; Cooper on laxity of the ligaments of the lower jaw, ii. 211; congenital dislocation of the lowerjaw,ii. 21 l;Guerin and Smith's cases, ii. 211; dislocation of the vertebra, ii. 211; dislocation of the first vertebrae very rare, and absolutely fatal, ii. 211 ; causes of dislocation of the first vertebra on the second, ii. 211; causes and symp- toms of dislocation affecting the last five cervical vertebrae, ii. 212; Walther on the simultaneous dislocation of both inferior oblique processes of one of the cervical vertebrae, ii. 212 ; Dupuytren on the con- founding cervical dislocation with rheu- matic affection of the neck, ii. 212; re- duction of the dislocation, ii. 213; dislo- cation of the dorsal and lumbar vertebrae always accompanied with fracture,ii.213; rupture of the ligaments, ii. 214 ; treat- ment, ii. 214; dislocation nflhepelvic bones, ii. 214; great violence requisite to cause dislocation, and the pelvic viscera, etc., generally injured, ii. 214; treatment, ii. 214; case of dislocation of the hip-bone upwards, unattended by concussion of the spinal marrow, of injury of the pelvic viscera, ii. 214 ; dislocation of the hip- bones more readily produced if the liga- ments be lax and yielding, ii. 215 ; treat- ment, ii. 215; dislocation of thecoccyx, ii. 215 ; treatment, ii. 215 ; dislocation of the ribs and their cartilages, ii. 215 ; dis- location of the hinder end of the ribs, ii. 215; Webster, Donne, Fimicane, and Hankel's cases, ii. 216 ; causes, situation, and symptoms, ii. 216; treatment, ii. 216; dislocation of the costal cartilages, ii. 216 ; treatment, ii. 216; Astley Cooper on dislocation of the costal cartilages, ii. 216; dislocation of the'collar-bone, ii. 2.17 ; is more rare than fracture, ii. 217; situation, ii. 217; varieties, ii. 217; symp- toms of dislocation of the sternal end forwards, ii. 217 ; of dislocation upwards, ii. 217; of dislocation backwards, ii. 217; Pellieux, Duverney, and Astley Cooper on the symptoms of dislocation back- wards, ii. 217; Tyrrell's case of compound dislocation backwards, ii.. 218; Velpeau's case of simple dislocation inwards and backwards, ii. 218; mode of reduction, ik218; Melier's apparatus for dislocation of tbe collar-bone forwards, ii. 219; Davije's operation for removing the dislo- cated sternal end, ii. 219 ; dislocation of the scapular end of the clavicle upwards, ii. 219; cause and symptoms, ii. 219; ANALYTICAL INDEX. 819 Tournel and Melle's cases of dislocation of the scapular end of the clavicle down- wards, ii. 219 ; mode ofreduction,ii. 220; South on the difficulty of keeping the dislocated scapular end reduced, ii. 220; dislocation of the upper arm, ii. 220 ; dis- location of the humerus more frequent than of any other bone, ii. 221; varieties of dislocation, ii. 221 ; Astley Cooper on a partial dislocation of the humerus, ii. 221; Hippocrates, Duverney, Fabricius ab Aquapendente, Desault, Mursinna, Richerand, Mothe, Velpeau, and Mal- gaigne on the primitive direction of dis- location of the humerus, ii. 221 ; symp- toms of dislocation downwards, ii. 221; of dislocation inwards, ii. 222; of dislo- cation outwards, ii. 222 ; of imperfect dis- location, ii. 222 ; causes, ii. 222; injury to the soft parts, ii. 222 ; dislocation of the humerus occasionally attended with frac- ture of the neck of the bone, ii. 222; re- duction of the dislocation, ii. 223; points to be attended to in effecting reduction, ii. 223; Rust's mode of reducing the dis- location, ii. 224 ; after-treatment, ii. 224 ; obstacles to reduction, ii. 224 ; reduction of the dislocation by means of the heel in the axilla, ii. 221; Bertrandi and Sauter's plans of reduction, ii. 225; reduction of the dislocation by means of the knee in the axilla, ii. 225; use of the pulleys, ii. 225; reduction of old dislocations, ii. 225; Weinhold's case, in which he divided the tendon of the pectoralis major, ii. 226 ; Gibson's case, in which the axillary artery was ruptured, ii. 226; Dieffenbach's case, in which he divided the tendons of several muscles, ii. 226 ; congenital dislo- cation of the humerus, ii. 226; not of very rare occurrence, ii. 226 ; two varieties of this dislocation, ii. 227 ; symptoms of the congenital subcoracoid dislocation, ii. 227 ; examination of a case of this dislo- cation after death, ii. 227; Smith on the post-mortem appearances in congenital sub-acromial dislocation, ii. 227 ; Smith on the resemblance between the congeni- tal sub-coracoid dislocation, and the par- tial dislocation, and that caused by rheu- matic affection of the shoulder-joint, and by unusual atrophy of the arm, ii. 228 ; evidence in favour of these dislocations being congenital, ii. 228 ; Guillard's case of reduction of a congenital dislocation after the lapse of sixteen years, ii. 228; dislocations of the fore-arm, ii. 228; dis- locations at the elbow-joint, ii. 228 ; com- plete dislocations of the elbow rare, ii. 228 ; dislocation backwards, ii. 228 ; dis- location of the ulna alone backwards, ii. 229; lateral dislocation, ii. 229 ; causes of dislocation of the fore-arm backwards, ii. 229 ; consequences of these disloca- tions, ii. 230; they soon become irredu- cible, ii. 230 ; complications of disloca- tion backwards, ii. 230; Astley Cooper, Bransby Cooper, Malgaigne, and Lis- franc's cases of reduction of old disloca- tions of the elbow, ii. 230; reduction of the dislocation, ii. 230; Astley Cooper's mode of proceeding, ii. 230; treatment to be adopted when the radius is also displaced, and in compound dislocation, ii. 230; reduction of the lateral disloca- tion, ii. 231; treatment of old disloca- tions, ii 231 ; treatment of dislocation forwards, ii. 231; dislocation of the radius backwards, ii. 231; dislocation of the upper end of the radius forwards, its causes and symptoms, ii. 231; Boyer, Astley Cooper, Rouyer, Villaume, Gerdy, and B. Cooper on dislocation of the upper end of the radius forwards, ii. 232; Bulley and Vignolo on simultaneous dislocation of the radius forwards and of the ulna backwards, ii. 232; Adams' case of longi- tudinal dislocation of the radius, ii. 232 ; reduction of this dislocation, ii. 232; Astley Cooper on the difficulty attending the reduction of this dislocation, ii. 232; dislocations of the wrist, ii. 232; three kinds of dislocation, ii. 232; dislocation of the hand from the bones of the fore-arm, ii. 232; varieties of this dislocation, ii. 232; Dupuytren doubts the occurrence of dislocation of the wrist, the presumed cases of which he regards as fracture of the lower end of the radius, ii. 233; Voil- lemier's case of dislocation of the wrist, ii. 233 ; Voillemier on the diagnostic signs of dislocation of the wrist, and fracture of the lower end of the radius, ii. 233; causes, ii. 233; mode of reduction, and after- treatment, ii. 233; dislocation of the radius alone, ii. 233 ; of the ulna alone, ii. 233; dislocation of single bones of the hand, ii. 234; dislocation of the great bone, and its treatment, ii. 234; Gras' case of dislocation of the pisiform bone, ii.234; partial dislocation of the great and unci- form bones, ii. 234; dislocation of the metacarpal bone of the thumb, ii. 234; reduction and after-treatment, ii. 234; dislocation of the phalanges of the fingers, ii. 234 ; mode of reduction, ii. 234 ; Roser and Fincke on dislocation of the thumb from the metacarpal bone, ii. 234; Desault, Dupuytren, Evans, and Vidal on the sur- gical treatment of this dislocation, ii. 235; Astley Cooper, Lisfranc, Dupuytren, Hey, Vidal, Malgaigne, Pailloux, Lawrie, Blechy, and Roser on the cause of the difficulty experienced in reducing this 820 ANALYTICAL INDEX. dislocation, ii. 235; Hey, Charles Bell, Fincke, Liston, Reinhardt, and Roser on the mode of reducing this dislocation, ii. 235 ; dislocation of the femur, ii. 235 ; divisions, ii. 236; Astley Cooper on the relative frequency of dislocations of the femur, ii. 236; South on repeated dislocations of the femur in the same person, ii. 236; symptoms of dislocation upwards and backwards, ii. 236; of dis- location inwards and downwards, ii. 237; Ollivier on dislocation of the femur di- rectly downwards, ii. 237; dislocation backwards and downwards into the ischi- atic notch, ii. 237; regarded by Boyer as secondary, ii. ^37; dislocation upwards and inwards, ii. 238 ; prognosis, ii. 238 ; the reduction of these dislocations, ii. 239; mode of reduction, ii. 239; Wattmann, Kluge, and Rust's methods of replace- ment, ii. 239, 40; Colombat's mode of reduction, ii. 241; reduction of these dis- locations by pulleys, ii. 241; Astley Cooper on the reduction of the dislocation downwards, ii. 242 ; Morgan and Cock on the reduction of the dislocated femur by placing the foot between the thighs, ex- tension and rotation being made at the same time, ii. 242 ; completion of the re- duction, and subsequent treatment, ii. 243; congenital dislocation, ii. 243 ; described by Hippocrates, Palletta, and Dupuytren, ii. 243; symptoms, ii. 243; Dupuytren and Palletta on the post-mortem appear- ances, ii. 244 ; Dupuytren on the local treatment of this dislocation, ii. 2.45 ; Duval, Jalade Lafond, Humbert, Pravaz, and Guerin on the reduction of this dislo- cation, ii. 245; Pravaz and Guerin's cases of successful reduction, ii. 245; Heine's apparatus, ii. 245 ; Guerin's mode of pro- ceeding in effecting the reduction, ii. 245; dislocation of the knee-cap, ii..246;'varieties, ii. 246; diagnosis, ii. 246; Coze and Wolf on twisting round of the patella, ii. 246 ; causes, ii. 246; mode of reduction, ii. 246; congenital dislocation of the patella, ii. 246 ; Palletta's case, ii. 247 ; dislocation of the knee-joint, ii. 247; of rare occur- rence, ii. 247; is generally incomplete, ii. 247; mode of reduction, ii. 247; Astley Cooper on dislocation of the semi-lunar cartilages, ii. 247; Wutzer and Kleberg on congenital dislocation of the knee, ii. 248 ; dislocation of the splint-bone (fibula), ii, 248; direction of the dislocation, ii. 248; mode of reduction, ii. 248 ; treatment, ii. 248 ; dislocation of the ankle-joint, ii. 248; direction of the dislocations^!. 249; symp- toms of the dislocation inwards, ii. 249 ; of the dislocation outwards, ii. 249<; dis- location of the foot forwards, ii. 249; dis- location backwards, ii. 249 ; consequences of these dislocations, ii. 250 ; mode of re- duction, ii. 250 ; Earle's case of disloca- tion of the ankle inwards, with laceration of the internal lateral ligament, ii. 250 ; compound dislocations of the ankle, ii. 251 ; South on the English practice in snch cases, ii. 251 ; dislocation of the bones of the tarsus, ii. 251 ; of very rare occur- rence, and only from great violence, ii. 251 ; dislocation of the astragalus, ii, 251; direction, causes, and symptoms, ii. 251 ; twisting round of the astragalus on its axis, ii. 252 ; Rognetta on dislocation of the astragalus inwards, ii. 252; James, Guthrie, and Stanley's cases of disloca- tion outwards, ii. 252; dislocation for- wards, ii. 252; dislocation inwards, ii. 253; dislocation outwards, ii. 253; Du- puytren, Boyer, and South on reduction of the dislocation, ii. 253; mode of re- duction, ii. 253; treatment to be adopted if the reduction be impossible, ii. 254 : removal of the astragalus, ii. 254; removal of the. bone necessary when it is twisted on its axis, ii. 254 ; the operation should be performed early, ii. 254; dislocation of the os calcis, ii. 254 ; South and Han- cock's cases, ii. 255; dislocation of the navicular and cuboid bones, ii. 255; always the result of great violence, ii. 255; mode of reduction, ii. 255; dislo- cation of the cuboid, ii. 255 ; treatment, ii. 256 ; dislocation of the great cuneiform bone, ii. 256; mode of reduction, ii. 256; Astley Cooper's cases, ii. 256; disloca- tion of the metatarsal bones, ii. 256; Dupuytren's case, ii. 256 ; mode of reduc- tion, ii. 256 ; Green's case of dislocation of the two outer metatarsal bones, ii. 256; dislocation of the toes, ii. 256; mode of reduction, ii. 256 ; Astley Cooper's case, ii, 256. Dixon's, Mr., case of resection of a costal cartilage, iii. 768. Dobson's, Sir R., treatment of erysipelas by punctures with a lancet, i. 125. Dodard, M., mortification from spurred rye first noticed by, i. 74. Doelunger, M., on the formation of new vessels, i. 324. Dohlhoff's, M., case of encysted abscess of the abdomen, iii. 216. Donige's, M., plan of bringing the edges of the cleft together in staphyloraphy, ii. 32; instrument for drawing the knots, ii. 33. Donne, M., on the microscopic characters of pus, i. 46; case of dislocation of the ribs, ii. 215. Dornbluth's, M., artificial leg, iii. 593. Douglas, Dr. James, on Cheselden's ope- ANALYTICAL INDEX. 821 ration for stone, iii. 314; on the dissection of the parts concerned in this operation, iii. 315. r Douglas, Mr. John, originally proposed the operation of lithectasy, iii. 375. Dran, Le, M., on superficial whitlow only a disease of the skin, i. 215; considers paronychia tendinosa to be caused by erysipelatous inflammation, i. 216; as- serts that Richter's dry whitlow depends on disease of the bone, i. 217; on'imme- diate amputation in gunshot wounds, i. 380 ; on the reduction en masse, ii. 274 ; on, ligature of the hernial sac for its radical cure, ii. 283; mode of operating in ovarian dropsy, iii. 210; mode of amputating at the shoulder-joint, iii. 712. Dubled, M., on extirpation of the womb, iii. 573; operation for excision of the wrist-joint, iii. 734. Dubourg, M., on the treatment of spina bifida by closure of the sac, iii. 190. Ducamp's, M., mode of cauterizing the urethra for stricture, iii. 81; mode of dilating the urethra after cauterization, iii. 81; caution respecting the use of caustic, iii. 82. Ducros, M., jun., on dislocation forwards on the share-bone in hip-disease, i. 287. Duges', M., obturator for vesico-vaginal fistula, ii. 189; on anteversion of the womb, ii. 415; case of spontaneous re- duction of anteversion, ii. 416. Duhamel, M., on mortification from spurred rye, i. 74. Duncan's, Dr., condemnation of the treat- ment of erysipelas by moderate compres- sion, i. 125. Duparque, M., on the fibrous or cartilagi- nous resistance of the tissue of the womb, i. 529; case of accumulation of blood in the womb, i. 530; on rupture of the womb during pregnancy, i. 530; on the danger and immediate treatment of rupture of the womb, i. 530; on partial rupture of the uterus from a collection of fluid in its parietes, i. 532; cases of abscess of the womb, i. 532; on puncture or narrow lacerations of the womb, i. 533; on the treatment of lacerations of the perineum, ii. 36; on the scarring of the edges of the torn perineum, ii. 36 ; case of recto- vaginal fistula cured spontaneously, ii. 198; on the indications for the treatment of recto-vaginal fistula, ii. 198. Duphoinix, M., on the use of a canula for maintaining the patency of the artificial duct in the operation for salivary fistula, ii. 148, 149. Dupuy's, M., experiments on the division of both pneumogastric nerves, i. 475. Dupuytren, M., on arteritis, a cause of dry gangrene, i. 72, 89; on the treatment of senile gangrene in plethoric subjects by the antiphlogistic plan of treatment, i. Ill; on incisions in pseudo-erysipelas, i. 124; treatment of pseudo-erysipelas and common erysipelas by blisters,!. 128; sub-division of burns, i. 126; on inci- sions in carbuncle, i. 157 ; on lumbar ab- scess generally connected with carious vertebrae, i. 210; on the changes that sometimes take place in the abscess, i. 211; leaves lumbar abscess to nature, i. 213; recommends cauterization, or weak injections of nitrate of silver, or nitric acid, in the treatment of the sinuous cavi- ties resulting from lumbar abscesses, i. 214; on ingrowing of the nail, i. 222; states it to have been mistaken for gout, i. 222; operation for dividing and re- moving the* diseased nail in ingrowing, i. 223; on onychia maligna, i. 223; on the removal of the nail with its secreting surface in treating onychia, i. 224; on the introduction of a piece of bougie into an ossified artery after amputation, i. 336; on the effects of torsion, i. 344 ; objections to torsion, i. 344 ; on the effects of gun-shot, i. 370 ; case of a person killed by a gun loaded with powder only, i. 370; on the splitting of the ball by the sharp edge of the bone, i. 375; on secondary hemor- rhage, i. 377; on amputation in tetanus, i. 419 ; case of abscess of the brain suc- cessfully opened, i. 439 ; distinguishes between commotion and contusion of the brain, i. 451; objects to the return of the. protruded omentum into the cavity of the abdomen in penetrating wounds of the abdominal parietes, i. 507; modifi- cation of Lembert's plan of treating wounded intestine, i. 515; experiments on the extravasation of bile and urine, i. 525 ; on the two periods in the forma- tion of bone, i. 548; on the production of callus, i. 556; treatment of fractured sternum, i. 598; treatment of fractured clavicle, i. 605; treatment of fracture of the humerus, i. 609; on fracture of the lower end of the radius, i. 611 ; on the treatment of fracture of the radius or ulna near the wrist, i. 613 ; on inversion of the foot in fracture of the neck of the femur, i. 618 ; on the treatment of frac- ture of the neck of the femur, i. 624 ; on the advantages of the double-inclined position, i. 625; on the duration of the treatment in these cases, i. 625 ; on the sawing off the ends of the broken bone in false joint, ii. 18; on the operation for the treatment of lacerated perineum, ii. 38; on the appearances presented on post-mortem examination some time after 822 ANALYTICAL INDEX. the cure of an artificial anus, ii, 156; ap- plication of the enterotome for the cure of artificial anus, ii. 158 ; Seller's modi- fication of it, ii. 159; on the symptoms of anal fissure, ii. 172; on the three varieties of anal fissures, ii. 172; on the treatment, ii. 172; treatment of recto-urethral and recto-vesical fistula, ii. 185; on cauteriza- tion as a means of cure in vesico-vaginal fistula, ii. 190; on the reduction of old dislocations, ii. 206; on congenital dislo- cations of the hip, ii. 207 ; on the causes of congenital dislocations, ii. 207; on the confounding cervical dislocation with rheumatic affection of the neck, ii. 212 ; doubts the occurrence of dislocation of the wrist, the presumed cases of which he regards as fracture of the lower end, of the radius, ii. 233; on the surgical treat- ment of dislocation of thenhumb from the metacarpal bone, ii. 235 ; on the cause of the difficulty experienced in reducing this dislocation, ii, 235 ; on congenital dislocation of the femur, iL 243 ; on the post-mortem appearances, ii. 244; on the local treatment, ii. 245 ; on reduction of dislocation of the astragal us, ii. 253; case of dislocation of the metatarsal bones, ii. I 256; on the reduction en masse, ii 274 ;l modification of the operation for femoral rupture, ii. 336; operation for mesenteric! strangulation, ii. 358; objections to scarifi- cations or leeches in treating prolapse of, the rectum, ii. 401; operation for long- standing prolapse of the rectum, ii. 402; objections to the actual cautery in irre- ducible prolapse, ii. 404; case of aneurism mistaken for abscess, ii. 474 ; on the section of the scalenus anticus in ligatdre of the subclavian, ii. 518 ; on the treat- ment of branching aneurism, ii, 554; plan! to prevent re-union after the operation for united fingers or toes, iii. 17; case of a foreign body remaining a long time in the windpipe, iii. 112; mode of operating for ranula, iii. 124; on the operative treat-; ment of encysted swellings, iii. 181; on cutting away the tunica vaginalis, iii. 230; bilateral section for stone, iii. 327; opera- tion for stone, iii. 347; on encysted cellu- lar fibrous tumor of the maxillary antrum and its treatment, iii. 486; operation for the excision of the cancerous neck of the womb, iii. 640; mode of amputation by the circular incision, iii. 610; practice of leaving the wound of the stump exposed for several hours after the operation, iii. 644; mode of dressing stumps, iii. 654; mode of amputating at the hip-joint with two flaps, iii. 692 ; at the shoulder-joint, iii. 712, 713, 716; mode of operating in exarticulation of the fore-arm at the elbow, iii. 719; on exarticulation of the middle and ring fingers, iii. 723; mode of opera- ting in excision of the elbow-joint, iii.733; recommends the non-division of the ulnar nerve in that operation, iii. 734; case of excision of the lower jaw, iii. 747; cases of extirpation of the upper jaw doubted by Gensoul, iii. 754. Dura mater, fungus of, iii. 419. Dussausoy, M., recommends emetics in hospital gangrene, i. 114; on the rotation of the foot outwards in fracture of the neck of the femur, i. 618. Duval's, M., local steam-bathing apparatus i.294; on the reduction of congenital dislocation of the femur, ii. 245 ; on the cause of club-foot, ii. 446. Duverney, M., on the lengthening of the limb in hip disease, i. 286; treatment of fractured olecranon, i. 614; apparatus for fracture of the neck of the femur, i. 623; on the symptoms of dislocation of the sternal end of the clavicle backwards, ii. 217 ; on the primitive direction of dislo- cation of the humerus, ii. 221 ; on the causes of club foot, ii. 446, Dyckman's, M., assertion that a child may be infected by the milk of a diseased nurse, ii. 105. Dzondi's, M., apparatus for fracture of the neck of the femur, i. 624; treatment of syphilis, ii. 100; urinary receptacles for vesico-vaginal fistula, ii. 189; plan of in- healing a plug of skin for the radical cure of rupture, ii. 283; mode of operating in ovarian dropsy, iii. 210; on the ligature of the carotid, prior to excision of the lower jaw writh the condyles, iii. 750. Earle's, Mr., comments on Dr. John Thompson's experiments with respect to the state of the vessels in inflammation, i. 39; on cold moist applications in the treatment of burns, i. 129 '} on the re- moval of the clothes after burns and scalds, i. 135 ; on the contraction of the cicatrix in cases of bums, i. 133 ; on the effects of this contraction, i. 139; opera- tion for the removal of the entire scar, i. 139 ; cases in which this operation was performed, i. 140; on dislocation into the ischiatic notch in hip disease, i. 287; ap- paratus for fractured clavicle, i. 603; treatment of fractured olecranon, i. 614 ; description of apparatus, i. 614; on some of the signs of fracture of the neck of the femur, i. 618; opposed to Astley Cooper's views on bony union in these fractures, i. 620; fracture-bed, i. 625; on urethroplasty, i. 179; obturator for vesico-vaginal fistula, i. 189; case of dis- location of the ankle inwards, with lacer- ANALYTICAL INDEX. 823 ation of the interna] lateral ligament, ii. 250; case of hydrocephalocele, ii. 363; case of hydrocephalocele treated by punc- ture, ii. 368; case of secondary haemor- rhage after lithotomy, iii. 335; case of chimney-sweeper's cancer in the wrist, iii. 560; on the extension of the disease to the neighbouring parts, iii. 560; on the age at which the disease generally occurs, iii. 560; case of division of the ulnar nerve, iii. 636. Ebel's, M., preparation of the parts for the operation of staphyloraphy, ii. 31; on the removal of the edges of the cleft, ii. 32; plan for bringing the edges of the cleft together, ii. 32; instrument for drawing the knots, ii. 32. Eberl's, M., straps for fractured clavicle, i. 603. Ebers, M., on the hydriodate of potash in syphilis, ii. 101. Eble, M., on the existence of the acarus scabiei, ii. 65; observations on the acarus, ii. 65. Echinoccus hominis, iii. 441. Eckoldt's, M., method of performing oeso-! phagotomy, iii. 160. Eckstrom's, M., operation for cutting into the urethra in the perineum, iii. 146. Eczema rubrum, or mercuriale, ii. 111. I Edmonston's, Mr., plan of treatment in ruptured tendo Achillis, i. 542. Ehrlich's, M., compressor, i. 330. Ehrmann, M., on the suture in vesico- vaginal fistula, ii. 193. Eichheimer's, M., apparatus for fractured clavicle, i. 603. Ekl's, M., opinion on the lymph-swelling, i. 61; on some of the signs of fracture of the neck of the femur, i. 618 ; on the in- locking of the broken ends of Jhe bone, i. 618; on the solution of the chloride of lime in the treatment of foul, gangrenous, or torpid ulcers, ii, 44. Elbow, dislocations of, ii. 228;, curvature of, ii. 462; exarticulation of the fore-arm at, iii. 718; excision of the, iii. 732. Elderton's, Mr., lithotritie instruments, iii. 285. Elliotson's, Dr., case of gangrene of the leg after the use of ergot, the arteries of the limb being also ossified, i. 74; on glanders in the human subject, i. 78; on the period of incubation of hydrophobia, i. 404; on the symptoms of hydrophobia, i. 405; on thediagnosis between true and spurious hydrophobia, and inflammation of the pharynx, i. 406; on a general morbid irritability in hydrophobia,i. 406; on the duration of the disease, i, 407; on abortive hydrophobia, i. 407; on the post- mortem appearances, i. 408; case of pro- lapse of the womb in a virgin, ii. 373. Elliott's, Mr., case in which he performed lithectasy, iii. 376. Else, Mr., denies the existence of the so- called scirrhus of the tonsils, i. 162; objection to excision of the tonsils, espe- cially in children, on account of the hae- morrhage, i. 165; prefers Cheselden's operation, i. 165; on the use of sutures in wounded intestine, i. 511. Elster, M., on the effects of torsion, i. 343. Emmert, M., on the phenomena of inflam- mation under the microscope, i. 41; ex- periments on the injection of bile into the cavity of the peritoneum, i. 526. Emery, M-, on the contagion of itch, de- pendent on the itch-mite, ii. 65. Emphysema, i. 496. Empyema, iii. 190. Enterotomy, iii. 106. Epididymitis. See Inflammation of the Tes- ticle. Epinychia, or ulceration with great thick- ening at the ends of the fingers, i. 217 ; Abernethy on the cure of epinychia, i. 221. Epulis, ii. 136. Erethismus mercurialis, ii. 108. Erysipelas ;—nature of the disease, i. 115; Rust's division into true and false erysi- pelas, i. 115; Hunter's opinion that most inflammations which are called erysipe- latous are not such, i. 115; South on the different applications of the terms erysi- pelas and erythema, i. 115; symptoms, progress, terminations, and causes of true erysipelas, i. 115; vesicular erysipelas, i. 115; the true erysipelas of Chelius the j erythema of English practitioners, i. 116; Willan's description of erythema, i. 116; Bateman's distinction between erythema, and erysipelas, i. 116; Rayer's descrip- tion of erythema, i. 116; the vesicular erysipelas of Chelius the acute erysipelas of Willan and Bateman, i. 116; the symptoms and progress of the disease, according to those authors, i. 116; causes of spurious or pseudo-erysipelas, i. 117; pseudo-erysipelas divided into erythema idiopathicum and erythema symptoma- ticum or consensuale, i. 117; causes of erythema idiopathicum, i. 117; SouthoB intertrigo a very frequent form of ery- thema idiopathicum,and on its causes,!. 117; causes of erythema symptoraaticum or consensuale, i. 117; Hunter's descrip- tion of erythema symptomaticum, i. 118; erythema symptomaticum the erratic ery- sipelas of Willan and Bateman, i. 118; erysipelas from scalp wounds the cedema- tous erysipelas of Willanand Bateman,i. 118; erythema symptomaticum a metas- tatic deposit in the cellular tissue, peri- osteum and glands in gastric, rheumatic, 824 ANALYTICAL INDEX. arthritic and puerperal diseases, i. 118; symptoms, progress, and terminations of the disease, i. 118; South's opinion that this form of erysipelas symptomaticum is the inflammation of the cellular tissue, commonly confounded with erysipelas and erythema, but decidedly different from either, although both occasionally run into it, i. 119 ; Hunter's description of the disease, under the name of erysipe- latous inflammation, i. 120 ; South's ac- count of the disease, i. 120; South's case of degeneration of the cellular tissue of the forehead and face, consequent on re- peated attacks of this disease, i. 120; Gulliver's description of thickening and induration, and of induration and rigidity without thickening of the cellular tissue of the feet and ankles, as occurring in soldiers, i. 121; distinctive characters of symptomatic and idiopathic pseudo-erysi- pelas,!. 121; etiology of pseudo-erysipe- las, i. 122 ; treatment of simple erysipe- las, i. 122; the antiphlogistic plan of treatment, i, 122; Dr.Williams'stimulant plan of treatment, i. 123; South on the combination of both the antiphlogisticand the stimulant plans, i. 123; the local treat- ment of erysipelas, i. 123; Rust on the application of moist warmth in vesicular erysipelas and its varieties,i. 123; treat-) ment of erysipelas when terminating in ulceration or gangrene, i. 123; South on the local treatment of erpsipelas, i. 123; Dobson's plan of relieving the hide-bound sensation by punctures with a lancet, i. 123; treatment of idiopathic erysipelas, i. 123; leeches never to be applied, but punctures made with a lancet, if neces- sary, i. 123 ; treatment of erythema con- sensuale, i. 123; Rust's stimulant and tonic treatment condemned by Chelius, i. 124; South on the treatment, of erysipe- las consensuale by incisions varying from an inch and a half to three inches in length, i. 124; Rust, Dupuytren and Lawrence of opinion that incisions should be made only in pseudo-erysipelas, and of the suitable length and depth, i. 124; Hutchinson, that they should be made early,and in considerable numbers, i. 125; Dobson employs numerous punctures with a lancet in all kinds oferysipelas, and on all parts of the body,i. 125; Dupuytren's treatment ofpseudo-erysipelas by blisters, i. 125; in some cases satisfactory, but the remedy doubtful, i. 125; his opinion that the suppuration produced by blisters on the inflamed part is the best mode of effecting resolution incommonerysipelas, i. 125; the extension oferysipelas arrested by some surgeons hy a blister at the mar- gin of the disease, i. 125; this plan of treatment rejected by others, i. 125; Bretonneau and Velpeau's treatment by moderate compression, i. 125; condemned by Lawrence and Duncan, i. 125 ; South on the application of nitrate of silver as a means of arresting the progress of the disease, i. 125; treatment of erysipelas consequent on wounds must be guided by a proper observation of its various causes, i. 125. Erythema of English practitioners, the ery- sipelas of Chelius, i. 116 ; Willan's de- scription of, i. 116; Bateman's distinction between, and erysipelas, i. 116; Rayer's description of, i, 116; erythema idio- pathicum, i. 116 ; erythema symptomati- cum, or consensuale, i. 117; Hunter's description of, i. 117; erythema symp- tomaticum the erratic erysipelas of Wil- lan and Bateman, i. 118; erythema symp- tomaticum, a metastatic deposit in the cellular tissue, periosteum, and glands, in gastric, rheumatic, arthritic, and puer- peral disease, i. 118; South's opinion that this is the inflammation of the cel- lular tissue, commonly confounded with erysipelas and eTythema, i. 119; Hunter's description of this form of the disease, i. 120 ; treatment of, i. 123 ; South on the treatment of, by incisions, i. 124. Ether, inhalation of, iii. 768 ; Morton and Bigelow's application of, as a safeguard against pain in tooth-drawing, iii. 768; employed by Warren, Hayward, Bige- low, Robinson, and Liston in more im- portant surgical operations,iii.768: South, Bigelow, Morris, and Cotton's cases of injurious effects produced by the inhala- tion of ether, iii. 769 ; South on the im- propriety of inhaling the ether, prior to the operation for cataract, iii. 770. Evans, Mr. on the surgical treatment of dislocation of the thumb from the meta- carpal bone, ii. 235. Evanson's, Dr. description of noma, i. 75; on the suppuration of mumps, i. 169; on the communication of syphilis to the infant in the womb, ii. 104; on the symp- toms of syphilis in infants, ii. 104; on the treatment of syphilis in infants, ii. 106. Evers', M., apparatus for divided and rup- tured tendons of the hand and fingers, i. 364; bandages for fractured clavicle, i. 603; objected to, i. 604; apparatus for fracture of the patella, i. 633. Exudation ;—period of its occurrence, and its results, adhesion and edema, i. 44; the term synonymous with effusion, i. 44; Dr. J. H. Bennett on the process of effu- sion, i. 44; Travers on the effusion of ANALYTICAL INDEX. 825 serum, 1. 44 ; Wharton Jones on exuda- tion, i. 45; Hunter on the cause of the ex- travasation of serum, i. 45; Gerberonthe varieties of exudation after inflammation, i. 45; Gerber on the microscopical resem- blance betweenthelymph-corpuscles and the exudation corpuscles,i. 45; this resem- blance denied by Gulliver, i. 46; Valentin on the exudation-corpuscles, i. 46; treat- ment after exudation has taken place, i. 101. Exostosis, iii. 408. Fabricius ab Aquapendente on tearino- out the tonsils,i. 164; on the primitive direction of dislocation of the humerus, ii. 221; on ligature of the hernial sac for its radical cure, ii. 283. Face, wounds of the, i. 469; important in wounds of the face to prevent scars, i. 469; use of sutures, i. 470; South on the twisted suture or thin pins in suehwourxls, i. 470; wounds of the region of the eye- brow, i. 470; cause of amaurosis in wounds of the eye-brow, i. 470; Thomson on amaurosis and inflammation of the eye, caused by the passage of a ball through or near the organ, i. 470; Fardeau's case of bayonet-wound entering the temple, and passing across through the opposite maxil- lary sinus, 471; De Limbourg's case of wound of the head with a ramrod, i. 47l; Hennen on gun-shot wounds in the neigh- bourhood of, or penetrating the orbit, i. 471; slight longitudinal and transverse wounds of the eyelids, i. 472; wounds of the ear, i. 472; South on wounds of the gristly passage of the ear, i. 472; wounds of the nose, i. 472; bandages for the nose, i. 473; wounds of the cheek, i. 473; wounds of the tongue, i. 473; deep and transverse wounds require sutures, i. 473; Lawrence on bleeding from the tongue from bites made during a fit, i. 473. Facial artery, ligature of, ii. 514. Falconer, Mr. on the lengthening of the limb in hip-disease, i. 285. Faraday, Mr. on the presence of globules in the serumi, i. 56. Fardeau's, M., case of bayonet-wound en- tering the temple, and passing across through the opposite maxillary sinus, i. 471. Fatio, M., on the use of the suture in vesi- co-vaginal fistula, ii. l9l. Faulquier's, M., artery-compressor, i. 331. Faure, M., on the propriety of delaying amputation in gun-shot wounds, i. 381. Faye, M., on the operation for the ingrow- ing of the nail, i. 224. Faye's, M. La, apparatus for fracture of the Vol. hi.—70 neck of the femur, i. 624 ; on the reduc- tion en masse, ii. 274. Featherstone's, Mr., case of fatal bayonet- wound of the heart, i. 499. Feet, curvature of, ii. 445. Feiler's, M., treatment of fractured ole- cranon, i. 614; description of his appa- ratus, i. 614. Femoral rupture, ii. 328. -------artery, ligature of, ii. 539. Femoral aneurism, ii. 535. Femur, fractures, of, i. 616; dislocation of, ii. 236. Ferne's, M., case of accidental torsion, i. 344. Fergusson's, Mr., case of protruded'spleen, i. 527; on the treatment of buboes, ii. 90. Fergusson's, Mr., new mode of staphylo- raphy, ii. 33 ; on dislocation of the knee after the divison of the hamstring ten- dons, requiring amputation, ii. 444; case of opening of the rectum into the bladder, ii. 38 ; case in which he performed the operation of lithectasy, iii. 378; operation for raising a sunken nose, iii. 591; on the relative value of the flap and circular operations for amputation, iii. 653; on amputation through the calf of the leg, and at the shoulder-joint, iii. 653; prefers Liston's flap operation for amputation of the thigh, iii. 660; reason why the hind flap should be longer than the front, iii. 660; recommendation to excise a con- siderable portion of the sciatic nerve in amputation with a single flap from behind, iii. 660; mode of amputating through the leg with two flaps, iii. 673; case of exci- sion of the head of the femur, iii. 739; mode of operating in resection of the up- per jaw, iii. 758; case of resection of the scapula and clavicle together, iii. 765 ; mode of operating, iii. 765. Ferrand's, Mr., case of aneurism mistaken for abscess, ii. 474, Ferrier, Dr., on an epidemic vaginal ca- tarrh, i. 181. Fest's, M., apparatus for fracture of the patella, i. 633. Fibula, fracture of, i. 635; dislocation of, ii. 248; resection of, iii, 768. Ficker, M., on the lengtheningof the limb in hip disease, i. 285; case of reduction of the consecutive dislocation, i. 297; advises the opening of abscesses at the hip with caustic, i. 298. Filkin's, Mr., case of excision of a joint, iii. 726. Fincke, M., on dislocation of the thumb from the metacarpal bone, ii. 234 ; on the mode of reducing this dislocation, ii. 235. 826 ANALYTICAL INDEX. Fingers, permanent bending of, ii. 464 ; supernumerary, iii. 597; amputation of, iii. 686; exarticulation of, iii. 723. Finucane's, M., case of dislocation of the ribs, ii. 216. Fischer, M., on the chemical composition of pus, i. 47; on the distinguishing tests for pus and mucus, i. 56; on the applica- tion of smear, black, or green soap, ii. 68. Fisher, Mr., on the origin of spina bifida, iii. 187. Fissures, anal, ii. 170. Fistula:, ii. 144 ; definition, ii. 144 ; John Hunter on the inadequacy of the term fistula, ii. 144; causes, ii. 144; Hunter on the causes of fistula, ii. 144; prognosis, ii. 145; indications for the cure of fistula, ii. 146; John Hunter on the cure of fistu- lae, ii. 146; salivary jistula, ii. 146; signs, ii> 146; causes, ii. 146; treatment, ii. 147 ; treatment of fistula of Steno's duct, ii. 147; restoration of the natural salivary duct, ii. 147; modes oftreatment proposed for that purpose, ii. 147; Desault, Richter, Schreger, and Viborg on the treatment of salivary fistula, ii. 147; production of an artificial duct, ii. 148; mode of operating, ii. 148; De Roy on the making an arti- ficial opening in the cheek, ii. 148; Percy on the passing a leaden thread into Steno's duct after the cheek has been penetrated. ii. 148; completion of the operation, i. 148; Duphoenix and Atti on the use of a canula for maintaining the patency of the arti- ficial duct,ii. 148; Croserio's modification of the operation, ii. 149; treatment of the fistula, ii. 149; Bonafont, Desault, Be- clard, and South on the treatment of fis- tula of the parotid duct, ii. 149 ; subse- quent treatment, ii. 150 ; fluctuating tu- mour of Steno's duct, ii. 150; stony concretion in the salivary duct, ii. 150 ; Syme, Astley Cooper, and Lawrence on salivary calculi, ii. 150; South on the specimens of salivary calculi in the Col- lege museum, ii. 150; biliary fistula, ii. 151; causes and symptoms, ii. 151; South on biliary fistulae, ii. 151 ; treatment, ii. 151; J'secularfistula, ii. 152; definition, ii. 152; signs, ii. 153; effects of faecular fis- tula and of artificial anus on the system, ii. 153; Begin's case of closing and wast- ing of the portion of intestine below the artificial anus, ii. 153; Astley Cooper's case of artificial anus in the jejunum ter- minating fatally, ii. 153 ; prolapse of the intestine at the artificial anus, ii. 153 ; symptoms and results, ii. 153; causes of faecular fistula and artificial anus, ii. 154; cure of artificial anus by nature and by operation, ii. 154; the process adopted in the cure by nature, ii. 154; Lallemand, Dupuytren, Scarpa, and Lawrence on the appearances presented on post-mortem examination, some time after the cure of artificial anus, iii. 155, 156 ; treatment of faecular fistula or arti- ficial anus, ii. 156; South's case of arti- ficial anus at the navel, ii. 157; King on artificial anus at the umbilicus, con- nected with the diverticulum ilei, ii. 157; South's case of flow of colourless fluid, from the navel, ii. 157; Lawrence on Du- puytren's operation for artificial anus, ii. 158; application of Dupuytren's entero- tome for the cure of artificial anus, ii. 158; Seller's modification of Dupuytren's en- terotome, ii. 158; Liordat'semporte-piece, ii. 158; Reybard's modification of the ope- ration, ii. 158 ; Delpech's enterotome, ii. 158; Desault and Schmalkalder on the treatment of artificial anus, ii. 159; Physick's operation for artificial anus, ii. 159 ; closure of the fistulous opening, ii. 160 ; Dieffenbach's cure of artificial anus from a lance-wound by the actual cautery, ii. 161; treatment of artificial anus con- nected with thecaecum, ii. 161; Velpeau's plan of treatment, ii. 161; rectal fistula, ii. 161; definition and sub-divisions, ii. 162 causes and symptoms, ii. 162; abscesses about the anus, ii. 162; Sabatier, Larrey, and Ribes on the internal opening of rec- tal fistula, ii. 162; Astley Cooper's case of fistula inano, ii. 163 ; examination of rec- tal fistulae, ii. 163; cure of the rectal fis- tula with an internal opening, only to be effected by division of the sphincter, and of the partition between the fistulous passage and the gut, ii. 163; contra-indications to the operation for rectal fistula, ii. 164; Brodie and Astley Cooper on the impro- priety of operating for fistula in phthisical cases, ii. 164; treatment of abscesses in the neighbourhood of the rectnm, ii. 164; Brodie on the treatment of large abscesses high up by the side of the rectum, ii. 165; usual modes of operating in rectal fistula, ii. 165; the operation by cutting, ii. 165; South on the operation for rectal fistula, ii. 166 ; operation for an internal blind fis- tula, ii. 167; dressing the wound, ii. 167; Pouteau, Walther, and Jaeger's objection to dressing the wound, ii. 167 ; Boyer, Sanson, Textor, and A. Cooper on dress- ing the wound, ii. 167; accidents which may occur during and after the operation, ii. 167; treatment of hemorrhage, ii. 167; of inflammation and suppuration, ii. 167; the hemorrhage occasionally but rarely, fatal, ii. 168; Copeland's objection to stuff- ing the rectum in cases of hemorrhage after the operation, ii. 168; Brodie on in- ANALYTICAL INDEX. 827 ternal erysipelas following the operation, ii. 168; ligature of the rectal fistula, ii. 168 ; Luke on the advantages of the liga- ture, and on the mode of operating, ii. 168; Dr. Nelken's instrument for applying the ligature, ii. 169 ; South on the ligature of rectal fistula, ii. 169 ; application of the leaden or silk-worm gut ligature in com- plete fistula, the internal opening not being high up, ii. 169; Desault, Reisinger, Weidman, Schreger, and Demme's ap- paratus for ligaturing complete fistula, ii. 169; mode of employing Reisinger's ap- paratus, ii. 169; treatment of fistula of the rectal sheath, ii. 169 ; Mott on the treat- ment of fistula of the rectal sheath, ii. 169; application of the ligature in an in- wardly blind fistula, ii. 170; re-application of the ligature sometimes necessary, ii. 170; advantages of the respective opera- tions by ligature and by cutting, ii. 170 ; treatment of rectal fistulae by compres- sion, ii. 170; treatment of externally blind fistulae, ii. 170; urinary fistula, ii. 174; definition and sub-division, ii. 174; situation of the external and internal openings, and direction of the fistulous passage, ii. 174; false urinary fistula, ii. 174; causes and appearances, ii. 174; incomplete internal urinary fistula, ii.174; causes and diagnosis, ii. 174; incomplete internal fistula from ulceration of the mu- cous membrane of the urethra, or from abscesses in the lacunae, ii. 175; South and Brodie on incomplete internal urinary fistula, ii. 175; complete urinary fistula, ii. 175; situation of the internal and ex- ternal openings, ii. 175; causes, ii. 175; symptoms and progress, ii.176; treatment of incomplete external fistula, ii. 176; of incomplete internal fistula, ii. 176; pre- sence of stones in the sac of a blind fis- tula, ii. 176; of complete urinary fistula, ii. 177; complete urinary fistula opening on the penis, ii. 177; symptoms, ii. 177; treatment of the accompanying stricture, ii. 177; of the fistula, ii. 177; treatment of the fistula when callous, ii. 177; Cooper and Dieffenbach on the treatment of callous fistulae, ii. 177; Cooper, Dief- fenbach, Zang, and Freimann on the su- ture of urethral fistula, ii. 178; Dieffen- bach on the introduction of the running stitch, ii. 178; Cooper, Earle, Alliot, Delpech, Ricord, and Dieffenbach on urethroplasty,, ii. 179; the operation of urethroplasty in fistulae near the scrotum, ii. 179; in large fistulae in the middle or fore part of the penis, ii. 179 ; in fistula close behind the prepuce, ii. 180; in large openings immediately behind the glands, with deficient prepuce, ii. 180; Charles Bell's Operation for the restoration of the canal of the urethra, ii. 181; causes, situation, and symptoms of complete urinary fistula in the hinder part of the urethra, ii. 181; Brodie on the causes of fistula in perineo, ii. 181; Brodie on the causes of perineal abscess, ii. 182; treat- ment of urethral fistula, ii. 182; Hunter, B. Bell, and Richter's objections to the use of the catheter in urethral fistula, ii. 182; Brodie on the treatment of fistula in perinaeo, ii. 183; operation for the cal- lous fistula in perineo, ii. 183; Brodie's case of malignant disease consecutive on neglected perineal fistula, ii. 184; ope- ration for the division of the stricture in great narrowing of the urethra, ii. 184; South on the operation for the division of the stricture, ii. 184; recto-urethral and recio-vesicalfistula, ii. 185; causes, symp- toms, and treatment,ii. 185; Dupuytren's treatment by the actual cautery or by caustic, ii. 185; Jaeger on the division of the sphincter muscle, ii. 185; Desault,. Dupuytren, and Zang on the treatment of these fistulae, ii. 185; Astley Cooper's operation for recto-urethral fistula, ii. 186; South's operation for recto-vesical fistula, ii. 186; vesico-vaginal fistula, ii. 188; causes, ii. 188; symptoms, ii. 188; diag- nosis, ii. 189; prognosis, ii. 189; the in- struments of Dzondi, Barnes, Schmitt, Burchard, Earle, and Duges, ii. 189; vaginal fistula, ii. 189; Desault, Baines, Guthrie, Rognetta, Coxe, and Jaeger on the treatment by drawing off the urine and by compression, ii. 189; Dupuytren, Lallemand, and Dieffenbach on cauteri- zation as a means of cure, ii. 190; Roon- huysen, Fatio,Voelter, Naegele, Schreger and Wutzer on the use of the suture, ii. 190, 191; mode of applying the suture, ii. 191,192; varieties of sutures, and their application, by Naegele, Roux, Schreger, Ehrmann, Kilian, Lallemand, Deuber, and Dieffenbach, ii. 192, 193; puncture of the bladder above the pubes after the operation, ii. 194; Dieffenbach and Wut- zer on the after-treatment, ii. 194 ; Jobert on the treatment of vesico-vaginal fistula by transplantation, ii. 195 ; Dieffenbach's treatment of the large fistulae by drawing the mucous membrane together, ii. 196; Dieffenbach's treatment of moderately large fistulae, ii. 197; Vidal's proposal to occlude the vulva, in complete destruction of the vagina and wall of the bladder, ii. 197; Horner's proposal to draw down the uterus into the vagina, ii.197; Dr. Keith's case of vesico-vaginal fistula, ii. 197; recto-vaginal fistula, ii. 198; symptoms, ii. 198; tendency to spontaneous cure, 828 ANALYTICAL INDEX. ii. 198; Duparcque's case, ii. 198; Du- parcque on the indications in the treats ment of this fistula, ii. 199; Copeland's operation by the division of the sphincter ani, ii. 199. Flammant's, M., apparatus for fractured clavicle, i. 603. Fleischmann's, M., description of the mu- cous bags beneath the tongue, iii. 123. Fleming's, Mr., case of ligature of the ex- ternal carotid for secondary haemorrhage, ii. 508. Fletcher's, Mr., instrument for oesopha- geal stricture, iii. 32. Fleury's, M., case of simple serous cysts of the neck, iii. 432. Fluctuation, occurrence and signsof, i. 44. Font ana, on the effects of viper bites, i. 389. Foot, fracture of the bones of, i. 639; arti- ficial, iii. 595; exarticulation of, at the ankle-joint, iii. 700; partial amputation of, iii. 703. Ford, on the treatment of abscesses at the hip, i. 298; cases of spontaneous cure of aneurism, ii. 489. Fore-arm, fracture of the bones of, i. 610; dislocations of, ii. 228; amputation through, iii. 681; exarticulation of, at the elbow, iii. 718. Foreign bodies, diseases, depending on the presence of, in the organism :— Definition and divisions, iii. 93 ; foreign bodies introduced into the body from with- out, iii. 94 ; foreign bodies in the nostrils, iii. 94 ; causes of retention, iii. 94 ; their removal, iii. 94; presence of balls from gun-shot wounds in thenostrils, iii. 94 ;! when the foreign body cannot be removed I it should.be pushed backwards into the mouth, iii. 94; Astley Cooper's case of' ball lodged in the frontal sinuses, iii. 94 ; I foreign bodies in the mouthy iii. 94 ; are readily removed or got rid of by suppu- ration, iii. 94; South's case of a piece of tobacco-pipe lodged in the cheek, iii. 94 ; foreign bodies in the asophagus, iii. 95;, situation of the foreign body, iii. 95 ; South's cases of, iii. 95 ; symptoms, iii. 96; diagnosis often difficult, iii. 96; sensation of soreness in the throat after) the extraction of the foreign body, iii. 96 ; South's case of fish-oone in the oesopha- gus, iii. 96 ; Monro's cases of halfpence in, iii. 97 ; Monro's case of a foreign body in a sac behind the oesophagus at its origin, iii. 97 ; removal of foreign bodies from the oesophagus, iii. 97; re- moval upwards, iii. 97; extraction of foreign bodies from the oesophagus by in- struments, iii. 97 ; thrusting them down i#lo the stomach, iii. 98 ; should not be attempted unless they be beyond the reach of the finger, iii. 98; Astley Cooper's case offish-bone at the glottis, iii. 98; Brown's case of a piece of broken delf plate in the oesophagus, iii. 98; Tunnaley's case of a bristle in the oesophagus, iii. 98; treatment when the foreign body has caused severe inflamma- tion and diseased contractions of the oeso- phagus, iii. 99 ; consequences of foreign bodies in the oesophagus, iii. 99; passage of thin and pointed bodies through its walls and the neighbouring parts, iii. 99 ; cases requiring cesophagotomy, iii. 99 ; South's preference of tracheotomy to cesophagotomy, iii. 100; directions for the operation, iii. 100; Eckoldt's method, iii. 100; Vacca Berlinghieri and Begin's directions for the operation, iii. 100 ; re- moval of the foreign body, iii. 102; after- treatment, iii. 102; foreign bodies in the stomach and intestinal canal, iii. 102; bulky bodies often pass away by the intestinal canal, pointed ones are retained, and cause inflammation and suppuration, iii. 102; Dr. Marcet and Dr. Barnes'cases of knife- swallowing, iii. 103; retention of bulky bodies and the symptoms they produce,iii. 104 ; obstructions of the ileum by a gall- stone, iii. 104; intestinal obstruction from lumps of carbonate of magnesia, and col- lections of cherry-stones, iii. 104 ; Lang- staff's case of a madman who swallowed a silver spoon, iii. 104 ; consequences of the presence of pointed bodies in the in- testines, iii, 105; general treatment in cases of foreign bodies in the stomach or intestines, iii. 105; Green's case of foreign body in the alimentary canal, iii. 105; extraction of the foreign body by gastro- tomy or enterotomy, iii. 105; Delpech's objections to these operations, iii. 105 ; Shoval's case of gastrotomy for the re- moval of a knife from the stomach, iii. 106; directions for gastrotomy, iii. 106; for enterotomy, iii. 106; enterotomy also advised for the relief of stricture and closure of the large intestines, for collec- tions of faeces, ileus, and volvulus, iii. 107; foreign bodies in the rectum, iii. 107 ; Phil- lips' case of a stick in the rectum, iii. 107; M'Laughlan's case of a large plug of wood in the rectum, iii. 107 ; Johnson's case of obstruction of the rectum by a large collection of peas, iii. 108 ; Brodie's case of apple-core in the rectum, iii. 108; Welbank s case of part of a vertebra and rib in the rectum, iii. 108 ; symptoms of obstruction from foreign body in the rec- tum, iii. 108 ; abscesses by the side of the rectum, iii. 108; Brodieand Green's cases, iii. 108; Coulson's case of closure of the ANALYTICAL INDEX. 829 rectum from the presence of a foreign body, iii. 108; extraction of the foreign body from the rectum, iii. 108; Marchetti's case of swine's tail in the rectum, iii. 109; Custance's case of a blacking-pot in the rectum, iii. 109; Lawrence's case of neck of a wine-bottle in the rectum, iii. 109;foreignbodies in the larynx andwind- pipe,ui. 109; symptoms,iii. 109; Porter on the passage of foreign bodies into the larynx, iii. 110; De la Martiniere's case of a foreign body in the windpipe, iii. 110; symptoms caused by a foreign body in the rima glottidis, iii. Ill; by a foreign body loose in the windpipe, iii. Ill; Bul- lock's caseof a quartz pebble in the upper part of the larynx, iii. III.; symptoms of a foreign body in one of the bronchi, iiu. 112; Sue, Dupuytren, Louis, Sutton, Paris, and Travers, jun.'s eases of foreign bodies in the windpipe during a long; fieriod of time, iii. 112;; the operation of aryngotomy or tracheotomy, iii. 113;; cases requiring the operation, iii. 113-; Stokes' cases of foreign bodies in the oesophagus inducing laryngeal symptoms, iii. 114; Cock's case of sixpence in the larynx, iii. 114 ; circumstances requiring the performance of laryngotomy, iii. 114; the operation must not be long delayed in angina laryngea, iii, 115; the operation useless in angina membranacea, iii. 115; Nevermann's statistics of tracheotomy in laryngitis and tracheitis, iii. 115; Breton- neau, Trousseau, and Kuby on the trache- otomy in croup, iii. 115; directions- for the operation of laryngotomy, iii. 1T5; South on the practice of inserting a tube in the larynx after the operation, iii. 116 ; South's case of fistulous- opening in the larynx from an attempt at suicide, iii. 116; division of the cartilage, iiu 116; removal* of the foreign body, iii; 117; directions for tracheotomy, iii. 117 ; removal of the foreign body, iii. 117; removal of a foreign body from the bronchus, iii. 117; Brodie and Macrae's cases, iii. 118; Liston and Dickin's oases of foreign bodies in the bronchus, in which trache- otomy was performed, and the foreign body extracted with forceps, iii. 118; South on the necessity of examining the larynx and the rima with a probe after these operations for the extraction of foreign bodies, iii. 119 ; circumstances to be borne in mind respecting bronchotomy, iii. 119 ; dangers of tracheotomy, iii, 120; the operation of laryngo-tracheotomy pre- ferable to tracheotomy, iii. 120; impor- tance of careful observation during these operations, on account of the variety in the course of the great blood-vessels, 70: iii. 120 ; unnatural collections curedoy^the application of the trephine, i.> 460-; parts of the skull where the trepan maybe applied, i. 460; the operation of trepanning, i. 461; directions for using the arch-trepan, i. 462; South on the distinction between the trepan and the trephine, i. 462; operating with the trephine, i. 463 ; South on the operation: of trephining, i. 463; trepanning on the I frontal sinuses, i. 464; South on trepan- ning on the frontal sinuses, i. 464 ; re- moval Of the piece of bone, i. 464; South I on the removal of the depressed and de- tachedhone, and of any points from the edge of the fracture, i. 464; application of several crowns, u464 ; South on the in- ftequency of the necessity to apply the trephine more than once, i. 464; com- pletion of the operation after the employ- ment of the trepan, i. 465; South on bleeding from the middle meningeal ar- tery or from a sinus, i. 465; after-treat- ment, i. 465; South on the after-treatment, i. 466; general treatment, i. 466; dressing the wound, i. 466 ; the process adopted by nature in filling up the opening in the skull, i. 466; unhealthy suppuration, i. 467; fungus of the dura mater, i. 467; fungus of the brain, i. 467; treatment, l. 467; protection of the part operated on by pads of leather, or of metal lined with wood, i. 467 ; Larrey on the subsequent effects of the closure of the opening in the skull, i. 467; various bandages for injuries of the head, i. 467 ; abscesses in the liver consequent on injuries of the head, i. 468; Hennen on sympathetic affections of the liver, stomach, lungs, and heart in injuries of the head, i, 468 ; Hennen on priapism in injuries of the head, i. 468; Hennen on loss of the gene- rative faculty from injuries of the back of the head, i. 468; causes of abscesses of the liver after injuries of the head, i. 468 ; Hennen on the sympathy between the brain and the liver, i. 469 ; signs and termination of abscesses of the liver, i. 469 ; treatment, i. 469. Heart, wounds of, i. 499 ; displacement of, ii. 361; actual protrusion of, ii. 361. Heath^s case of excision of the uterus by the abdominal section, iii. 578. Hecht on the chemical constituents of the brain-like substance in medullary fungus, iii. 458. Hedenus' apparatus for fracture of the neck of the femur, i, 623. Heine's case of reduction of the consecutive dislocation in hip-disease, i. 298; artifi- cial leg, iii. 593. Heister's artery-compressor, i. 331; band- age for fractured clavicle, i. 603; ob- jected to, i. 603. Held on the division of the peronei mus- cles in splay-foot, ii. 458. Hellmund's mode of applying Cosme's powder, as a caustic in the treatment of cancer, iii. 514. Henle's opinion that the exciting cause of inflammation operates through the ner- vous system, i. 37; discovery of fatty vesicles in the serum of pus, i. 52; on the continuity of synovial membrane over the cartilage of joints, i. 236; on the fibrous structure of articular cartilage, i. 249 ; on the non-vascularity of cartilage, i. 249; explains the absorption of carti- lage from want of nutriment, i. 261; on the formation of new vessels, i. 324. Hennen, Dr., on the after-management of the ligature on arteries, i. 339; on the shock caused by a gun-shot wound, i.372; on severe bruising by shot, i. 374; on the treatment of wounds by a ball in the fleshy part of the arm, thigh, or buttock, i. 376; on the use of the seton to bring away separated pieces of bone, i. 377; on the occurrence of necrosis in gun-shot injuries of bones, i. 377; on the nature of the injuries in gun-shot wounds requiring amputation, i. 379; on immediate ampu- tation, i. 381; on the fatal character of tetanus, i. 419; on cold lotions in bruises of the scalp, i. 426; on sabre wounds of 858 ANALYTICAL INDEX. the head, i. 427; cases of sabre cuts of the head, i. 427; does not agree with Astley Cooper that the trephine should be used in all cases of compound fracture of the skull, and gives cases of musket- shot fracture in illustration, i. 433; on gun-shot wounds of the skull, and their effects, i. 434; on perforation of the skull by bayonet-thrusts, i. 436; on the re- moval of foreign bodies in injuries of the brain, i. 4,38; on the loss of certain facul- ties from concussion,!. 450; on sympa- thetic affections of the liver, stomach, lungs, and heart in injuries of the head, i. 468; on priapism in injuries of the head, i. 468; on the loss of the generative faculty in injuries of the back of the head, i. 468; on the sympathy between the brain and the liver, i. 468 ; on gun-shot wounds in the neighbourhood of, pene- trating the orbit, i. 471; on emphysema in wounds of the wind-pipe, i. 474; case of wound of the larynx and oesophagus, i. 480; case of severe nervous symptoms following gun-shot wound of the throat, i. 480; on the course taken by balls in woundsof the chest, i. 483; on the prog- nosis of wounds of the chest, i. 488; on the occurrence of primary and secondary haemorrhage in incised or punctured wounds of the chest, i. 490; on the im- mediate treatment of penetrating wounds of the lungs, i. 494; on emphysema, i. 495; case of secondary emphysema,!.495; on the healing of wounded lung, i. 496; on the protrusion of a portion of lung, i. 497; case of foreign body in the heart, i. 499; case of wound of the pericardium, i. 500; on the escape of the intestines from injury in penetrating wounds of the abdomen, i. 501; on the treatment- of penetrating wounds of the abdomen, i. 505 ; on the use of the suture in wounded intestine, i. 513 ; on effusion into the cavity of the abdomen in cases of pene- trating wounds, i. 518; ease of musket- shot wound of the abdomen, the ball passing afterwardsper anum, i. 520; case of ball wound of the pelvis, involving the bladder, i. 528 ; on the duration of syphilis under the non-mercurial treat- ment, and on the subsequent occurrence of secondary symptoms, ii. 103. Hernandez' experiments on the iden- tity of syphilis and gonorrhoea, i. 183, 185. Hernia :—definition, ii. 258; divisions, ii. 259 ; ruptures of the belly, ii. 259 ; situa« tion, ii. 259 ; varieties of ruptures, ii. 259 ; South on certain forms of ruptures, ii. 259 ; parts forming the rupture, ii. 259; presence of the hernial sac, ii. 259; cases in which it is absent, ii. 259; South on the presence of the sac in vesi- cal and ccecal hernia, ii. 259 ; Taramelli's case of hernia of the vermiform appendix, ii. 260; sub-divisions of the sac, ii. 260; its coverings, ii. 260; changes which take place in the hernial sac, and their causes, ii. 260; case of ossification of the sac, ii. 260; South on the causes of stricture in the body of the sac, ii. 260; South on the hour-glass contraction of the hernial sac, ii. 261; size of ruptures, ii. 261; several ruptures often occur in the same person, ii. 261 ; double hernial sac very rare, ii. 261; Bransby Cooper, Lawrence, and Astley Cooper on the double hernial sac, ii. 261 ; Morgan's case of a pouch formed at the mouth of the tunica vaginalis, ii. 262; vertical di- vision of a hernial sac into two, ii. 262; South on the occasional rupture of one side of the sac in femoral hernia, ii. 262; reducible and irreducible ruptures, ii. 263; congenital or acquired ruptures, ii. 263 ; causes of ruptures, ii. 263; ruptures more frequent in men than women, ii. 263 ; Lawrence and Cloquet on the sta- tistics of ruptures, ii. 263,264; symp- toms of a reducible abdominal rupture, ii. 266; diagnosis, ii. 266; South on the difficulty of distinguishing between in- testinal and omental rupture, ii. 266; symptoms of intestinal rupture, ii. 266; South on the gurgling noise in the rup- ture, ii. 266; symptoms of omental rup- ture, ii. 266; of vesical rupture, ii. 266; of other ruptures, ii. 266 ; ruptures al- ways important diseases, ii. 267; forma- tion of adhesions in the sac, ii. 267; con- dition of the intestine in the sac, ii. 267; of the omentum, ii. 267; South on the thickening of the intestine in the sac, ii. 267; causes of strangulation, ii. 267; seat of strangulation, ii.267; signs determining the seat of the strangulation, ii. 267; Mal- gaigne and Didayon the seat of strangu- lation, ii. 268 ; distinction between incar- ceration and strangulation, ii.269; Scarpa, Lawrence, Travers, Boyer, von Walther, Jaeger, Langenbeck, Wilhelm, Blasius, A. Cooper, Rust, Sinogovitz, and Seiler on the nature of strangulation, ii. 269; South on incarceration and strangulation, ii. 270; symptoms of acute strangulation, ii. 270; South on costiveness as a symp- tom of strangulation, ii. 270; South and Luke on the dilatation of strangulated rupture on coughing, ii. 270; Astley Cooper on the complication of strangu- lated hernia by the presence of an irre- ducible rupture, ii. 271; symptoms of strangulation with a less degree of in- ANALYTICAL INDEX. 859 flammation, ii.271; causesand symptoms of incarceration, ii. 271; spasmodic in- carceration, ii. 271; symptoms of gan- grene of the hernia, ii. 272; strangulation of the omentum, ii. 272; may terminate in suppuration or gangrene, ii. 272; Key on the propriety of active general and local depletion in strangulated omental hernia, prior to the operation, ii. 272; treatment of ruptures, ii. 272 ; of reduci- ble ruptures, ii. 272; reduction of the rupture, ii. 272; South on the application of the taxis, ii. 273; South on the danger attending violence in the application of the taxis, ii. 273; South, LeDran, De la Faye, Arnaud, Louis, Richter, Scarpa, Sabatier, Dupuytren, Sanson, Lawrence, Key, and Sir Charles Bell on the reduc- tion en masse, ii. 274 ; Green and Calla- way's case of reduction en masse, ii. 274; Bransby Cooper's case, ii. 275; Luke on reduction en masse, ii. 275; Cloquet's ex- planation of the manner in which this accident takes place, ii. 275; Luke on the signs indicative of the reduction eh masse, ii. 276; Dupuytren and Luke on the ope- ration required after the reduction en masse has occurred, ii. 277; re-descent of a reduced rupture prevented by appro- priate bandages, ii. 279; trusses, ii. 279; application of the truss, ii. 280; a truss with a hollow pad required in adherent rupture, ii. 280 ; a suspender to be used for large, irreducible ruptures, ii. 280; effects from wearing the truss, ii. 281; Cloquet on the spontaneous return of the hernial sac into the abdomen, ii. 281; ra- dical cure of reducible ruptures, ii. 281; five modes of attempting it, ii. 282 ; Hil- danus, Blegny, Winslow, Richter, Lan- genbeck, Boyer,Ravin, and Beaumont on the use of increased pressure, and the supine posture for that purpose, ii. 282; Jalade Lafond's pad with a reservoir for caustic, ii. 282; Paulus yEgineta, Avi- cenna, Kern, Franco, and Monro, on the application of the actual cautery or caus- tic for the purpose, ii. 282; ligature and stitching of hernial sac, ii. 283; prac- tised with various modifications by Be- rard, Franco, Pare, Nuck, Fabricius ab Aquapendente, Guy de Chauliac, Le Dran, Freitag, Senff,Schmucker,Theden, Langenbeck, Kern, Petit, Lieutaud, Le- blanc, Mauchart, Richter, Dionis, Mery, Arnaud, Schreger, von Graefe, and vonj Walther, ii. 283; the inhealing a plug of skin, ii. 283; Dzondi, Jameson, and Gerdy's plans, ii. 283; Gerdy's mode of operating,ii.283; modified by Signoromi and Wiitzer, ii. 284 ; Bransby Cooper s case, in which he performed Gerdy s ope- ration, ii. 284; Bonnet, Mayor, and Bel- mas' operations for the radical cure of hernia, ii. 285; circumstances guiding the decision as to the performance of an ope- ration for the radical cure of hernia, ii. 286; the several operations for the radical cure more or less dangerous, ii. 286; opi- nions differ as to the value of these ope- rations, ii. 287; Schreger's indications when the operation is admissible, ii. 287; Astley Cooper's case, in which he in- effectually removed the entire hernial sac, ii. 288; Astley Cooper's objections to the ligature of the sac, ii. 288; Petit'scase of approaching peritonitis caused by ligature of the sac, ii. 288; Lawrence's objections to operations for radical cure of hernia, ii. 289; treatment of strangulated rup- ture, ii. 289; employment of tobacco ene- mata, ii. 289; South's objections to the use of tobacco enemata, ii. 289; treatment of chronic strangulation, ii. 290; employ- ment of the taxis, ii. 290; symptoms fol- lowing the reduction, ii. 290; symptoms followingfailure of the taxis, ii.291;Ribes and Hey on the application of the taxisj ii. 291; O'Beirne on the introduction of a thick elastic tube through the rectum into the sigmoid flexure of the colon, ii. 291; Ribieri and Guerin on local anodyne applications, ii.-292; Nember, Rennerth, and Preiss on the exhibition of purga- tives, &c, ii. 292; Church on the use of tartar emetic, ii. 292 ; Bell on the muriate of morphia, ii. 292; South's case of mortified intestine from strangulation, ii. 292; the proper time for operating, ii. 293 ; South on the proper time at which the operation for strangulated hernia should be performed, ii. 294 ; steps of the operation, ii. 294 ; preliminary measures, ii. 295; description of the operation, ii. 295; South's objection to lifting up a fold of the skin, and incising it, ii. 295; South on the length of the first incision in scro- tal and femoral ruptures, ii. 295; exposure of the sac, ii. 295; South on the division of the coverings, and opening the hernial sac, ii. 296; South on several cases of in- ternal strangulation by bands from the mesentery or diverticula of the ilium, ii. 296; dilatation of the seat of strangulation by cutting, ii. 297; instruments for divid- ing the. strangulating part, ii. 297 ; South on the division of the stricture, ii. 297; dilatation without cutting, ii. 297; re- commended by Thevenin, Leblanc, Le- cat, Arnaud, Richter, and Scarpa, ii. 298; South's objections to dilatation without cutting, ii. 298; return of the intestines after the division of the stricture, ii. 298; South on the return of the intestines after 860 ANALYTICAL INDEX. the division of the stricture, ii. 298; South on the effusion of fluid after the intestine have been returned, ii. 298; causes which impede the reduction of the intestine, ii. 298 ; treatment of adhe- sions, ii. 298 ; treatment of intestine dis- tended with faeces or air, ii. 298 ; Lowe, Loeffler, Richerand, Jonas, and von Graefe on puncturing the distended in- testine, ii. 298; South on the treatment of adhesion between the omentum or in- testine and the sac, ii, 298 ; South's ob- jections to puncturing or incising the in- testine, unless distended with solid mat- ter, ii. 299; treatment of degenerated omentum, ii. 300; its removal by liga- ture or incision, ii. 300 ; Sonth and Cal- loway's cases, ii. 300; Key's advice to unfold the omentum before cutting it off, ii. 300 ; South's mode of treating the pro- truded omentum, ii. 301 ; sloughing of the omentum, ii. 301; Astley Cooper's case, ii. 301 ; Hewett on the formation by the omentum of a sac enclosing the intestine, ii. 301 ; South on secondary haemorrhage from the omentum,ii. 301; Key on abscess in the sac, occasionally reproducing the symptoms of strangula- tion, ii. 302 ; the dark violet or even dusky colour of the intestine should not prevent its reduction, ii. 302; South on this colour, as caused by venous congestion, ii. 302; gangrene of the intestine, and its treatment, ii. 302; treatment of wounded and nar- rowed intestine, ii, 302; treatment df old irreducible ruptures when strangu- lated, ii. 303 ; the operation of dilating the abdominal ring, the hernial sac ndt being opened,'to be rejected in the ma- jority of cases, ii. 303; cases in which it may be adopted, ii. 303 ; this proceeding adopted by Franco, Pare, Petit, Garen- geot, Monro, A. Cooper, Key, and Preiss, ii. 303 ; advantages of this operation, ii. 303 ; Guerin's subcutaneous incision of the abdominal ring, ii. 303; Astley Coop- er's reasons for recommending the opera- tion of dividing the stricture without opening the sac in large and old ruptures, ii. 303; mode of operating, ii. 304; Law- rence's modification of this operation, ii. 304; Key's views with regard toi.his ope- ration, ii. 305; Lawrence ascribes the fatal results after the operation, not to the ex- posure of the parts to the air and light, but to the effects of protracted constric- tion, ii. 305; South on the consequences of the constriction, and on violence in the application of the taxis, ii. 305 ; Key and South on the signs indicative of gan- grene of the intestine, ii. 306; Key and South's cases of gangrenous intestine, in which a fetid smell was perceptible be- fore the sac was opened, ii. 306; absence of the fetid smell not a certain sign of healthy intestine, ii. 307; Lawrence re- commends opening the sac, and dividing the stricture from within, ii. 307; South on the division of the stricture external to the sac, ii. 307; South on the treatment after the operation, ii. 307; Luke's de- scription of the operation for dividing the stricture external to the sac, ii. 307; Luke on the diagnosis of the seat of stricture, ii. 308 ; Luke on the incision of the sac, or on partial division of its neck in seve- ral places, when the stricture is caused by it, ii. 308; treatment after the opera- tion, ii. 308; treatment when the symp- toms of • strangulation persist after the operation, ii. 309; Key and South on suppuration of the sac, ii. 309 ; Soutii's case of extensive sloughing of the abdo- minal and lumbar cellular tissue after the operation, ii. 309 ; treatment of sloughy intestine, ii. 310; formation of an arti- ficial anus, ii. 310; adhesion of the gut to the mouth of the sac when sloughing takes place, ii. 310; Astley Cooper and Key's cases of sloughing of the intestine, after it had been returned into the abdo- men, ii. 310; Ramsden's case of fatal -contraction and ulceration of the intestine after strangulation, ii. 310; Key and South on the occurrence of gangrene in the intestine some days after the opera- tion in persons of enfeebled constitution, ii. 310, 311; Key on the fatal termina- tion of cases after the operation, when preceded by great depression of powers, ii. 311; Astley Cooper's case of tetanus after the operation, ii. 311; tabular view of operations for strangulated rupture, ii. 316; inguinal rupture, ii. 316 ; situation and varieties, ii. 316; anatomy of the parts concerned, ii. 316; South's descrip- tion of the fascia transversalis, ii. 318; external or oblique inguinal rupture, ii. 319; situation and direction, ii. 319 ; in- ternal or direct inguinal rupture, ii. 319 ; -situation and direction, ii. 319; diagnosis between these only possible when small and recent, ii. 319; coverings of the ex- ternal or oblique inguinal rupture, ii. 319; imperfect inguinal rupture, or rupture in the inguinal canal, ii. 319; situation and coverings, ii. 319; South on the coverings of this variety of rupture, ii. 320; cover- ings of the internal or direct inguinal -rupture, ii. 320; comparative frequency of protrusion of the respective viscera, ii. ;320 ; congenital inguinal rupture, ii. 320; ■•causes, ii. 320; distinguished from exter- ANALYTICAL INDEX. 861 nal inguinal rupture, ii. 321; coverings of congenital inguinal rupture, ii. 321; nar- rowing of the hernial sac, ii. 321; con- genital inguinal hernia called by Astley Cooper encysted hernia of the tunica va- ginalis, ii. 321; diagnosis of rupture from hydrocele, ii. 321 ; South on the diffi- culty of diagnosis between rupture and hydrocele of the cord, ii. 322; South's cases of hydrocele of the cord mistaken for rupture, ii. 322; complication of rup- ture with hydrocele, i. 322; Mr. T. Bli- zard and Cline's jun. cases of hydrocele in front of an inguinal rupture, ii. 323 ; diagnosis between rupture and varicocele, ii. 323; and inflammatory swelling of the spermatic cord, ii. 324; and the ar- rest and inflammation of. the testicle in the inguinal canal, ii. 324; Key's case of strangulated inguinal rupture, the testi- cle being at the external ring, ii. 324; diagnosis between inguinal ruptures and fat-ruptures, ii. 324; collections of fat on the surface of the peritoneum, ii; 324; Pelletan on the mechanism of the fat- rupture, when it descends through the inguinal canal, ii. 325; diagnosis between inguinal rupture, and collections of pus passing through the inguinal canal out at the abdominal ring, ii. 325; return of the inguinal rupture, ii. 325; application of the truss, ii. 326; seat of strangulation, ii. 326; the operation for strangulated in- guinal rupture, ii. 326; important in old scrotal rupture on the right side, to as- certain whether the secum or commence- ment of the colon be the protruded vis- cus, ii. 326; direction of the cut in divid- ing the stricture, ii. 326; South on the direction of the cut in dividing the stric- ture, ii. 327 ; congenital inguinal rupture, ii. 327; process of the radical cure, ii. 327; operation for strangulated congeni- tal inguinal rupture, ii. 327; the opera- tion for inguinal rupture, without open- ing the sac, ii. 328; external inguinal rupture in women, ii. 328; Nuck and Cloquet on the diverticulum of the perito- neum, ii. 328; Allan Burns on the fre- quency of congenital rupture in the fe- male, ii. 328; femoral rupture, ii, 328; situation and sub-divisions, ii.329; Logier on oblique femoral rupture, ii. 329 ^ana- tomy of femoral rupture, ii. 329 ; South on the anatomy of femoral rupture, ii. 330; femoral rupture occurs more rarely than inguinal, and more frequently in women than in men, ii. 33-2 ; symptoms of femoral rupture, ii. 332; Astley Cooper and Callaway on the seat of femoral rup- ture, ii. 333; South on the diagnosis of femoral from inguinal rujpture m women, Vol hi.—73 ii. 333; Astley Cooper and South on the presence of other tumors in the femoral region likely to be mistaken for femoral rupture, ii. 333; coverings of femoral rupture, ii. 333; parts protruded in femo- ral fupture, ii. 333 ; South on the cover- ings of femoral rapture, ii. 333 ; Berard's case of femoral rupture, in which the Fallopian tube was protruded, ii. 334; situation of the epigastric and obturator arteries with respect to femoral rupture, ii. 334; of the spermatic cord, ii. 334; application of the taxis, ii. 334; situation and severity of the strangulation in fe- moral rupture, ii. 335; Key on the seat of strangulation in femoral rupture, ii. 335; the operation for strangulated femo- ral rupture, ii. 335; direction of the in- cision, ii. 335; precautions to avoid wounding the epigastric or obturator ar- tery, ii. 336; Hesselbach's modification of the operation, ii. 336; Scarpa and Du- puytren's modification, ii. 336; Key on the operation for the femoral rupture, ii. 337; after-treatment, ii. 337; external femoral rupture, ii. 337 ; situation, signs, and coverings, ii. 337; predisposing causes, ii. 337; application of the taxis, ii. 338; Astley Cooper on the Varieties of femoral rupture, ii. 338; South's cases of femoral rupture, with two sacs, ii. 339; wounds of the epigastric of obtura- tor artery, ii. 341; Lawrence on the sta- tistics of these wounds, ii. 342; Law- rence's case of fatal haemorrhage from a wounded branch of the epigastric, ii. 342; Everard Home's case of suppura- tion of the testicle consecutive to the operation for strangulated scrotal rupture, followed by severe haemorrhage, ii. 342; umbilical rupture, ii. 343; situation and sub-divisions, ii. 343; congenital um- bilical rupture, ii. 343; symptoms, ii. -343; South on the ligature of the umbili- cal cord, ii. 343; causes of umbilical fupture, ii. 343; in adults, ii. 343; co- verings, ii. 844 ; strangulation of rare oc- currence, ii. 344 ; Astley Cooper's case; in which the sac was either absorbed or burst, ii. 344; Cline and South's cases of double umbilical ruptures, ii. 344; Astley Cooper on the enormous size of umbilical ruptures in women, ii. 344; treatment of congenital umbilical rupture, ii. 344; treatment of umbilical fupture occurring after birth, ii. 345; Rothmund's plan of treatment^ ii. 345; Desault, Soemmering, and Briinning- hausen's case of spontaneous cure of umbilical rupture, ii. 346 ; the operation for strangulated umbilical rupture, ii. 346; Astley Cooper on the danger of 862 ANALYTICAL INDEX. sloughing of the integuments in strangu- lated umbilical rupture, ii. 346 ; Astley Cooper on suppuration of the omentum in strangulated umbilical rupture, ii. 346; strangulation of umbilical rupture rarely occurs during pregnancy, ii. 346 ; Astley Cooper, Lawrence, and Clement's cases, ii. 346; radical cure of reducible umbili- cal rupture by ligature objectionable, ii. 346 ; opposed by Scarpa, Astley Cooper, Benedict and South, ii. 347; Desault's fatal case, ii. 347; ventral rupture, ii. 348; definition and situation, ii. 348; causes, ii. 348; Oloquet's case of lumbar rupture, ii. 348; South's cases of rupture of the linea alba, ii. 348; Lawrence's case of rupture of the recti abdominis, ii. 348; case of a boy wounded by a boar's tusk, with protrusion of the omentum, colon, and some small intestines, ii. 349; Richter and Siebold's cases of yielding of the abdominal parietes, ii. 349; situa- tion, contents, and coverings of these ruptures, ii. 349 ; signs and treatment, ii. 349 ; diagnosis betweep ventral ruptures and fat-ruptures, ii. 349 ; stomach rup- tures, their symptoms and treatment, ii. 350; treatment of the other ventral rup- tures, ii. 350 ; ischiatic rupture, ii. 350; seat and contents, ii. 350; diagnosis, ii. 350; congenital ischiatic , rupture, ii. 350; diagnosis from a fatty or encysted swelling, ii. 350; from spina bifida, ii. 351; coverings, ii. 351 ; reduction, ii. 351 ; Astley Cooper and Seiler on the operations for strangulated ischiatic rup- ture, ii. 351 ; Hager on the upper and lower ischiatic ruptures, ii. 351 ; Scarpa treats ischiatic rupture as enlarged pudic rupture in women, and enlarged perineal rupture in men, ii. 351; thyroid rupture, ii. 351; situation and boundaries, ii. 352; contents, ii. 352; Cloquet and Lawrence on thyroid rupture, ii. 352; Franz' case of apparent strangulated thy- roid rupture, ii. 352; diagnosis, ii. 353; treatment, ii. 353; Astley Cooper and Gadermann on the operation for strangu- lated thyroid rupture, -ii. 353 ; vaginal rupture, ii. 353 ; situation and contents, ii. 353; symptoms, ii. 353; predispos- ing causes, ii. 354; treatment, ii. 354; perineal rupture, ii. 354; situation and contents, ii. 355; of rare occurrence, ii. 355 ; characters of the rupture, ii. 355 ; reduction, ii. 355; Astley Cooper's pu- dendal hernia, the posterior labial rup- ture of Seiler, ii. 355 ; rectal rupture, ii. 356; causes, signs, and diagnosis, ii. 356 ; treatment, ii. 356; phrenic rupture, ii. 356 ; different ways in which this oc- curs, ii. 356; Macaulay and Astley Cooper's cases, depending on malforma- tion of the diaphragm, ii. 357; Leacock's case of fatal phrenic rupture, ii. 358; mesenteric and mesocolic ruptures, ii. 358; nature of the injury, ii. 358; disease ne- cessarily fatal, ii. 358; Dupuytren's operation, ii. 358; strangulation of in- testine within the peritoneal cavity (internal hernia,) ii. 359; Astley Cooper on internal strangulation, ii. 359; Lawrence on the symptoms of internal strangulation, ii. 359; Rokitansky on internal strangulation, ii. 359; ruptures of the chest, ii. 360; very rare, ii. 360; na- ture and causes, ii. 360; Gratelup and Sabatier's cases, ii. 360; symptoms and treatment, ii. 360; displacement of the heart, ii. 361; Breschet, O'Bryen, Ramel, and Deschamps' cases, ii. 361; Stokes' case of displacement of the heart from ex- ternal violence, ii. 361; actual protrusion of ihe heart, ii. 361; Chaussier's cases, ii. 361; ruptures of the brain, ii. 362; nature of the disease, ii. 362; South on cerebral rupture, ii. 362 ; congenital cerebral rup- ture,ii. 363; causes, situation, symptoms, and results, ii. 363 ; post-mortem appear- ances in congenital cerebral rupture, ii. 363 ; Otto on hydrocephalocele, ii. 363 ; Penada, Earle, and Baron's cases, ii. 364; the fluid sometimes contained between the brain and its membranes, ii. 364; Meckel and Otto on the causes of cerebral rupture, ii. 364; double congenital cere- bral rupture, ii. 365; Billard and Meckel's cases of cure, ii. 365; accidental cerebral rupture, ii. 365 ; Beck and South on acci- dental cerebral rupture, ii. 365 ; Jamie- son's case, ii. 366; diagnosis of accidental cerebral rupture from the so-called fungus of the dura mater, ii. 366; between con- genital cerebral rupture and the blood- swellings of newly-born children,ii. 366; from watery cysts, ii. 366 ; treatment, ii. 367; by puncture, ii. 367; operations generally fatal, ii. 367; Earle and Adams' cases of hydrocephalocele treated by puncture, ii. 367; danger of the puncture, ii. 367; Pitschaft's cases of suppurating protrusions in children, ii. 368. Hernia humoralis. See Inflammation of the Testicle. Herpes and its varieties, ii. 57. Hertwig's observations on canine mad- ness, i. 397; experiments show that the saliva is the vehicle of the poison in hy- drophobia, i. 397; also show the conta- gion to be in the blood of the mad beast, i. 397. Hesselbach's artery-compressor, i. 331; modification of the operation for femoral rupture, ii. 336; on the treatment of hy- ANALYTIC drocele by caustic, iii. 229; mode of am- putating at the shoulder-joint, iii. 714. Hbtling's case of osteo-sarcoma of the jaws, in which he.removed part of the upper, and part of the lower jaw, iii. 760. Heurteloup's percuteur, advantages and disadvantages of, iii. 288. Hevin's case of renal calculus communi- cating with abscess in the loins, iii. 268. Hewett on the formation, by the omentum, of a sac inclosing the intestine, ii. 301; on the connexion between the cord or the nerves, and the walls of the sac in spina bifida, iii. 188 ; on puncturing spina bi- fida, iii. 189. Hewson's opinion relative to the formation of pus, i. 46; operation for the excision of the carious head of the femur in hip- disease, i. 300; on the use of caustic to destroy the ends of broken bones in false joints, ii. 17; case of cure of false joint by caustic potash, ii. 17; case of excision of the head of the femur, iii. 737. Hey on the possibility of infection from secondary syphilis, ii. 106; on the cause of the difficulty experienced in reducing dislocations of the thumb from the meta- carpal bone, ii. 234 ; on the mode of re- ducing this dislocation, ii. 235; on the application of the taxis in strangulated hernia, ii. 291; on the cause of the diffi- culty in reducing the bowel in old pro- lapses of the rectum, ii. 402; operation for prolapse of the rectum, ii. 402 ; case of effusion of blood into the knee-joint, iii. 178; on the incontinence of urine conse- quent on lithotomy in women, iii. 353 ; case of immense tumour of the nose, iii. 598; mode of amputating the thigh with the flap from behind, iii. 660; on amputa- tion just above the ankle, iii. 674 ; mode of operating in exarticulation of the meta- tarsal bones, iii. 706. Heyfelder on the varieties of lardaceous tumours founded on microscopic exami- nation, iii. 452; operation for the resec- tion of both upper jaws, iii. 758. Heyne's apparatus for fracture of the neck of the femur, i. 624. Higginbotham's treatment of burns by the nitrate of silver, i. 136; on the treatment of whitlow with nitrate of silver, i. 219. Hildanus' apparatus for fracture of the neck of the femur, i. 623; on increased pressure and the supine posture in the radical cure for hernia, ii. 282. Hill on the duration of syphilis under the non-mercurial treatment, and on the sub- sequent occurrence of secondary symp- toms, ii. 103. . Hip, abscess of, i.282 ; curvature of, n. 443, AL INDEX. 863 amputation of the thigh at, iii. 688; ex- cision of, iii. 735. Hippocrates on congenital dislocation of the hip, ii. 207, 2l3; on the primitive direction of dislocation of the humerus, ii. 221. Hirtz on the physical phenomena of pleu- ritic effusion, iii. 193. Hodgkin, Dr., on the development and progress of scirrhus, iii. 499; on the diagnosis between scirrhus and medul- lary fungus, iii. 503. Hodgson's cases of arteritis, i. 89; on severe phlebitis, i. 92 ; on the bursting of aneu- risms, ii. 470; on the relative frequency of aneurism in the sexes, ii. 475; on the relative frequency of' aneurism in the arteries, ii. 476; on the application of pounded ice to aneurisms, ii. 480; on compression in the. treatment of aneurism, ii. 483; on the effects produced by the ligature on the arterial coats, ii. 492; ease of aneurism of the posterior cerebral, ii. 513; on the section of the scalenus anticus in the ligature of the subclavian, ii. 518 ; proposal to tie the innominata, ii. 521; on ligature of the innominata, ii. 522; on spontaneous aneurism of the brachial, ii. 528; on the coagula in vari- cose veins, ii. 568. Haematocele, iii. 175. Haemorrhoids, ii. 581. Hoere's case of simultaneous collection of blood between the pericranium and skull, and between the dura mater and skull, the latter being fissured, iii. 175. Hcering's experiments on the injection of bile into the cavity of the peritoneum, i. 526. Hoffmann's opinion relative to the forma- tion of pus, i. 46; cases of separation of the head of the femur, and its removal by the surgeon in hip disease, i. 287. Holbrook on the treatment of hydrocele by seton, iii. 229. Holscher's case of trepanning the spine, i. 590; cases of extirpation of the womb, iii. 570. Home's, Sir E., opinion relative to the for- mation of pus, i. 47; on the internal use of arsenic and ginger as a cause of gonorrhoea, i. 182; cases of gonorrhoea in the female, in which the use of stimulating injections caused the sides of the vagina to unite to- gether by adhesive inflammation, i. 193; on the application of a ligature above a viper's bite, i. 390; case of the bite of a rattlesnake, i. 392; on the appearances in the lungs 32 years after their having been wounded by a ball, i. 487; case of suppuration of the testicle consecutive to the operation for strangulated scrotal 864 ANALYTICAL INDEX, hernia, followed by severe haemorrhage, ii. 342; on the Hunterian operation, ii. 490 ; on the non-necessity for the exist- ence of large collateral branches to ensure the success of the Hunterian operation, ii. 491; on acupuncture of aneurism, ii. 503; on the ligature of* the saphena vein or varix, ii. 5.72; on the use of the armed bougie in stricture of the urethra, iii. 79; case of relapse of hydrocele a long while after the operation, iii. 228 ; case of foreign body the nucleus of a stone, iii. 249; case of retention of urine, and consequent mortification, from the impaction of calculi in the urethra, iii. 363; on atheromatous cysts and their contents, iii. 433 ; on the question as to the propriety of removing a scirrhous breast, iii. 539. Hook-foot, ii. 460. Horner's Dr., recommendation to divide the sphincter ani in lacerated perineum, after union has taken place, ii. 40 ; pro- posal to draw down the uterus into the vagina in cases of vesico-vaginal fistula, to act as a plug, ii. 197. Horns, iii. 402.. Horse-foot, ii. 460. Houston's case of fracture of the haunch- bone, followed by abscess in the peri- neum, and urinary fistula,i..597; apparatus for fracture of the neck of the femur, i. 623. Houte's apparatus for fracture of the neck of the femur, i. 623. Howship's case of distension of the bladder by blood, iii. 134. Hrury's palate-holder, ii. 33r Huberthal's apparatus for fractured clavi- cle, i. 603. i Huguier on the period at which syphilis shows itself after birth, ii. 104. Hulse's treatment of false joints, ii. 17. Humbert's case of reduction of the conse- cutive dislocation in hip disease, i. 297; on the reduction of congenital dislocation of the femur, ii. 245, Humerus, fracture of, i. 606; dislocation of, ii. 220. Hummel on the arrest of haemorrhage by nature, i. 330. Hunczorsky's mode of amputating at the hip-joint with the flap-cut with a single flap, iii. 691. Hunter, John, on inflammation, i. 33; on the susceptibility for inflammation, and the influence of the constitution with respect to its local effects, i. 34; on the cause of pain in inflammation, i. 36 ; on the causes of inflammation, i. 37, 38; on the attendant redress, i. 37; experi- ments on the increase of heat in inflam- mation, i. 37; opinion on the enlarge- ment of the vessels in inflammation, i. 38; on the cause of the extravasation of serum", i. 45; opinions relative to the formation of pus, i. 46; on the cause and results of suppuration, i. 47; on suppurative in- flammation, i. 49; on the circumstances which determine an abscess to the sur- face,!. 50; on the qualities of pus, and the pus-globules, i. 51; on the putrefaction of pus, i. 51; on ulcerative inflammation, i. 62; ulcerative absorption, or absorption with suppuration, i. 62, 63 ; progressive absorption, i. 63; on inflammation of the mucous membranes, i. 87; of the serous membranes, i. 87; on the occasional ter- mination of inflammation of serous mem- branes in suppuration, i. 88; on the coagulation of the blood in phlebitis, i. 93; on severe phlebitis, i. 93; on the red streaks accompanying inflammation of the absorbents, i. 96 ; on inducing resolu- tion by constitutional means, i. 97; direc- tions respecting the employment of blood- letting, i. 97; on the local means of in- ducing resolution, i. 98 ; on fomentations or steams, washes, and poultices, i. 100; on derivation,i. 101; first pointed outthe membrane of the fistula, i. 108; descrip- tion of it, i. 108; opinion that most in- flammations which are called erysipe- latous, are not such, i. 115; description of erythema symptomaticum, i. 118; de- scription of metastatic erythema symp- tomaticum, under the name of erysipe- latous inflammation, i. 120; on cold in the treatment of burns, i. 129; on the pri- mary treatment of burns, i. 133; on the contraction of the granulations during cicatrization, i. 138; experiments in freezing rabbits' ears, i. 144; on the ef- fects of frost-bite, i. 145; mentions another inflammation very like chilblains, i. 149 ; on the inflammation that produces car- buncle, i. 154; his observation that there are generally more carbuncles than one not confirmed by South, i. 154; his opi- nion that carbuncle has some affinity to boils, i. 155 ; on the period when gonor- rhoea first makes its appearance after in- fection,!. 176; on the primary symptoms of gonorrhoea, i. 176; on the specific extent of the inflammation, i. 176 ; on the actual seat of the discharge, i. 177; on the small swellings which are noticed externally near the urethra, i. 177; on the size and form of the stream of urine, i. 177; on the occurrence of haemorrhage in severe gonorrhoea, i. 177; on inflam- matory and spasmodic chordee, i. 178; on the extent of local irritation, i. 178 ; on the extension of the inflammation to ANALYTICAL INDEX. 865 the bladder, and the consequent inability of that viscus to retain its contents, i. 178; case of fever preceding gonorrhoea, i. 178; on the extension of the inflammation in the female to the bladder, i. 180 ; doubts its extension to the ovaries, i. 180; on abscesses complicating gonorrhoea in the female, i. 181; on gonorrhoea from simple causes, i. 182; case of gonorrhoea caused by leucorrhcea in the female, i. 182; on the identity of syphilis and gonorrhoea, i. 182; accounts for the two different effects of the same poison, by the gonorrhoea proceeding from a secreting surface, and the chancre being formed in a non-se- creting surface, i. 182; on the sympathetic swellings in gonorrhoea, 188; on the duration and spontaneous cure of gonor- rhoea, i. 190; on the treatment of the disease, i. 190; on the remedies for chordee, i. 192 ; on the arrest of haemor- rhage from the urethra, i. 192; on the infectious nature of gleet, i. 194; on balanitis, i. 198; on the period when swelled testicle supervenes, i. 198; swell- ing of the testicle arises from sympathy, and not from syphilis,!. 198 ; on gout, as a cause of orchitis, i. 198; on the fungus which projects when a whitlow bursts, i. 215; reasons for the severity of the pain, and the length of time before a whitlow bursts, i. 216; regards whitlow as an example of the ulcerative process having no power over the cuticle, i. 218 ; on the treatment of whitlow, and its free and early incision, i. 219; on inflammation of the joints, i. 230; on the ulcerative ab- sorption of cartilage, i. 254 ; on anchy- losis, i. 268; on the inflammatory and scrofulous diseases of joints, causing an- chylosis, i. 269 ; on soft anchylosis from granulations, i. 269; on bony anchy- losis, i. 269 ; case of soft anchylosis from the extension of inflammation from the surrounding parts to the joints, i. 272 ; on the shortening and lengthening of the diseased limb in hip disease, i. 284; on the three kinds of union of divided parts —quick union, by adhesion, and by granu- lation,!. 319 ; description of quick union, i. 319; objected to by Dr. John Thomson, i. 319; on the adhesive inflammation, in connection with wounds, i. 321; on the formation of new vessels, i. 323 ; on sup- puration and granulation as leading to cicatrization, i. 324; on the suppression of haemorrhage, i. 341; on the means for keeping the lips of a wound in apposition, i. 357; on the use of sticking plaster or the dry suture for wounds, i. 359 ; on the use of sutures, i. 360; on gun-shot wounds, l. 370; on the character of gun-shot wounds, 73 i. 374; objections to primary amputation, i. 381; on the cause of death in tetanus, i. 418; on the causes of tetanus, i. 418 ; on puncturing the dura mater, when the extravasation lies beneath it, i, 448; on the suppurative inflammation of wounded joints, i. 537; on rupture of the tendo Achillis, i. 540; on the treatment of the ruptured tendon, i. 540; on the period of union, and the manner in which it takes place in simple fracture, i. 548; on the consequences of compound frac- tures, i. 558; Qn the treatment of com- pound fracture, i. 565; on symptomatic fever, i. 571; on hectic fever, i. 571; on the removal of the injured limb during the continuance of hectic fever, 572; on the slight constitutional irritation after amputation, when union by the first intention takes place, i. 573; on the pro- cesses which follow after union has taken place in fractured patella, i. 633; on the formation of false joints, ii. 14; on the treatment of false joints, ii. 15; on the two modes in which the venereal poison affects the system, ii. 71; on the period at which chancres appear after in- fection, ii. 71; on the symptoms of chancre, ii. 72; experiments by inocu- lating with the matter of gonorrhoea and chancre, ii. 72; on the true venereal bubo, ii. 75; on the existence of syphi- litic buboes without primary sore, ii. 76; on the continuance of the constitutional irritation from lues, independent of con- tinued absorption, ii. 77; on the non- infectious character of the pus from a secondary syphilitic sore, ii, 79; on the relative rapidity of cure of gonorrhoea, chancre, and lues venerea, ii. 85; on the relapse of ulcers after chancres have cicatrized), ii. 85; case of diseased child infecting the nurse, ii. 105; on the pos- sibility of infection from.secondary syphi- lis, ii. 106; on the ossific inflammation preceding necrosis, ii. 121; on the process of exfoliation, ii. 124; on the signs of exfoliation, ii. 125»; on the species of ex- foliation, ii. 128; on the inadequacy of the term fistula, ii. 144 ; on the causes of fistula, ii. 144; on the cure of fistula, ii.. 146; objections to the use of the catheter in urethral fistula, ii. 182; definition of aneurism, ii. 469 ; on the coagulatione prospect of ultimate success in this operation in cases of malignant disease, iii. 761 ; dressing the wound, and after-treatment, iii. 761; dangerous symptoms which may occur after the operation, iii. 761; recurrence of the dis- ease, iii. 761. Jeaffreson on the extirpation of the ovary, iii. 210; case of extirpation of the ovary, iii. 211; on the statistics of the operations1 for ihe extirpation of the ovary, iii. 213. Jenner's, Dr., discovery of vaccination, iii. 622. Jewel, Dr., on the distinguishing signs between leucorrhea and gonorrhea, i. 181. Joachim's artery-compressor, i. 331. Jobert's practice in wounded intestine, l. 509 ; on the introduction of the seton in false joints, ii. 20; on the treatment of vesico-vaginal fistula by transplantation, ii. 195; case of ligature of the popliteal in the internal epichondyloid pit. ii. 543. Johnson's, Dr., case of obstruction of the rec- tum, by a large collection of peas, in. 10H. Joikts, excision of, iii. 726; first performed Vol. iii.—74 on the knee-joint, iii. 726; afterwards extended to the other joints, iii. 726; Filkin, Vigaroux, David, White, Bent, Orred, Park, Moreau, Graefe, and Davie's cases, iii. 726; Sabatier, Percy, Roux, Moreau, Larrey, Guthrie, Syme, Textor, and Jaeger on the excision of joints, iii. 726; Wachter, Vermandois, Kohler, and Chaussier's experiments, iii. 727; objec- tions to this operation as compared with amputation, iii. 727; advantages of the operation, principally referable to the joints of the upper extremities, iii. 727; not so great in operations on the other joints, iii. 727; statistics of Jaeger, Syme, and Moreau's cases, iii. 727; Crampton on the excision of joints, iii. 728; cases in which excision of the ends of bones is preferable to amputation, iii. 728; con- tra-indications to the operation, iii. 729; mode of operating, iii. 729; direction and extent of the incision in the skin, iii. 729 ; excision of the diseased bone, iii. 729 ; extent of bone required to be re- moved, iii. 729; instruments for excising the ends of bones, iii. 730; arrest of the subsequent haemorrhage, iii. 730; dress- ing the wound, iii. 730; after-treatment, iii. 730; untoward occurrences during the after-treatment, iii. 731; after-bleed- ing, iii. 731; abscesses, iii. 731 ; fistu- lous passages, iii. 731 ; necrosis of rare occurrence after this operation, iii. 731; after-treatment of the sawn ends of the bone, iii. 731; excision at the shoulder- joint, iii. 731 ; mode of operating in ex- cision of the head of the humerus, iii. 732; C. White, Orred, Bent, Sabatier, Moreau, and Syme's modes of operating, iii. 732; motions of the arm subsequent to the operation, iii. 732 ; excision of the elbow-joint, iii. 733; Moreau's mode of operating, iii. 733; Dupuytren and Syme's modes of operating, iii. 733; Moreau on the division of the ulnar nerve in this operation, iii. 733; Dupuytren, Cramp- ton, Jaeger, and Syme recommend its preservation, iii. 733; Jaeger's mode of operating, iii. 734; condition of the arm after excision of the elbow-joint, iii. 734; Crampton and Syme's cases, iii. 734; excision of the wrist-joint, 734 ; Roux and Jaeger's modes of operating in excision of the lower ends of the radius and ulna, iii. 734 ; dressing the wound and after- treatment, iii. 735} Dubled and Vel- peau's operation, iii. 735; Butt's case of excision of part of the necrosed ulna, iii. ■735; excision of the hip-joint, iii. 735; mode of operating, iii. 735; by a simple longitudinal cut, iii. 736; by the forma- tion of a flap, iii. 736; by Textor's oval 874 ANALYTICAL INDEX. cut, iii. 736; dressing the wound, iii. 736; White, Carmichael, Oppenheim, Hewson, Seutin, and Textor's cases, iii. 737; C. White on excision of the head of the femur, iii. 737; A. White and Fer- gusson's cases of excision of the head of the femur, iii. 738, 739; excision of the knee-joint, iii.740; Moreau, Park, Mulder, Sanson, Begin, Jaeger, and Syme's modes of operating, iii. 740 ; Jaeger's operation preferred, iii. 740; Moreau, Park, and Jaeger on the mode of union after the operation, iii. 740; Syme on the treat- ment after the operation, iii. 741 ; A. White's case of compound dislocation of the femur behind the leg, iii. 741; ex- cision of the ankle-joint, iii. 742; Moreau, Jaeger, Mulder, and Kerst's modes of operating, iii. 743; South on excision of the ankle-joint, iii. 743; dressing the wound, and after-treatment, iii. 744 ; ex- cision of the joints of the metacarpus and metatarsus, iii. 744; mode of operating, iii. 744; after-treatment, iii. 744; Textor, Kramer,Roux,and Fricke's'cases,iii.744. Joints, Inflammation of :—inflammation may be set up as the primary disease in any part of the joints, such as the liga- ments, synovial membranes, cartilages, and spongy ends'of the bones, i. 229; Hunter on inflammation of the joints, i. 230; causes and nature, 230; Inflam- mation of the ligaments, i. 230; Brodie on the rarity of affections of the ligaments j independent of other structures, i. 230; Mayo's case of injury to the ligaments of the knee, i. 230; Wickham's obser- vations on inflammation of the ligaments, i. 231; symptoms of acute inflammation of, i. 231; South on the absence of dis- criminating signs between acute inflam- mation of the ligaments and rheumatism, i. 231; symptoms of chronic inflamma- tion of the ligaments, i. 232; terminations of the acute and chronic form of inflam- mation, i. 232; changes of structure in the joints, i. 232; Key on ulceration in ligamentous fibre, i.233; South on relaxa- tion of the ligaments, i. 233; treatment of inflammation of, i. 233 ; treatment of, thickening and swelling of the cellular! tissue, i. 233; of suppuration external to the joints, i. 234; of suppuration internal to the joints, i. 234; this latter malady is Wickham's disease of the cellular mem- brane of joints, i. 234; Wickham's de- scription of the disease, i. 234 ; South's cases of abscesses external to the joint, i. 235; South on the position of the limb during disease of the knee-joint, i. 235; Inflammation of the synovial membrane, i. 235; W. Hunter on the structure of sy- novial membrane, i. 236; Henle on the continuity of synovial membrane over the cartilage of joints, i. 236; Toynbee on the synovial membrane, i. 236; Clopton Ha- vers, and Goodsir on the mucilaginous glands, i. 237; Brodie on the diseases of the synovial membranes, i. 237; symp- toms of inflammation of, i. 237; Brodie on the two varieties of synovial inflamma- tion, i. 238 ; Brodie's case of acute syno- vial inflammation terminating in suppu- ration and ulceration, i. 238; Wickham's case of synovial inflammation terminating in ulceration, i. 239; suppuration of the synovial membrane, after wound of tbe joint, i. 239 ; Brodie on the sub-acute or chronic form of synovial inflammation, i. 239; symptoms and progress of the dis- ease, i. 239; Lawrence on the diagnosis of fluctuation in synovial inflammation, i. 240; Lawrence on hydrarthrus or hy- drops articuli, i. 241; Dr. Watson on the difference between synovial inflam- mation and inflammation of the ligaments, i.241; Astley Cooper on gonorrheal rheu- matism and gonorrheal ophthalmia,i.242; Cooper's case of gonorrheal rheumatism and ophthalmia,]. 242; Brodie on gonor- rheal rheumatism and ophthalmia, i. 242; Brodie and Lawrence on the pulpy de- generation of the synovial membrane, i. 242; South on the non-malignancy of this pulpy degeneration, i. '243 ; Brodie on its causes and progress, i. 243; post- mortem appearances, i. 244; South on the nature of the respective diseases, as indicated by the post-mortem appearances i. 244; causes of synovial inanimation, i. 244; prognosis, i. 244; treatment, i. 244; Brodie and South on the local treat- ment, i. 245; if suppuration ensue, the swelling should be punctured early, i. 246; treatment to be adopted, after the inflammation is subdued, there remaining swelling from effusion of fluid, i. 246; South on the use of blisters for promoting the absorption of the effused fluid, i. 246; Brodie on the use of friction in such cases, i. 246; treatment of the chronic form of inflammation, i. 246; after the occurrence of suppuration, with destruc- tion of the cartilages and bones, i. 246; South on irritantapplications in the treat- ment of the chronic form of the disease, i. 246; South's case of disease of the synovial membrane of the knee-joint, attended with evidence of fluctuation, in which the swelling was punctured with- out benefit, i. 247: Inflammation of the cartilages, i. 248; William Hunter on the structure of cartilage, i. 248; Miescher says " no difference between permanent ANALYTICAL INDEX. 875 cartilage and that which is to be con- verted into bone," i. 249; he differs in opinion with W. Hunter as respects the fibrous structure of articular cartilage, i. 249 ; Todd and Bowman consider there is a difference between temporary and articular cartilage, i. 249; Henle on the fibrous structure of articular cartilage, i. 249; Henle and Toynbee on the non- vascularity of cartilage, i. 250; Toyn- bee on the development of cartilage, i. 250; Toynbee on the supply of nutrient fluid to articular cartilage, i. 250; Toynbee on the vessels by which the articular cartilages are nourished, i. 251; Toynbee's description of the canals in adult cartilages, i. 252; Meckel, Bi- chat, and Muller on the vessels of carti- lage, i. 252, 253; Brodie's opinion that cartilages are vascular, i. 253; Toynbee, Beclard, and Cruveilhier distirictly of opinion that cartilages are devoid of vas- cularity, i. 253 ; W. Hunter's views on the structure of cartilage generally cor- rect, i. 253; symptoms of inflammation of cartilage, i. 253; Mayo on three distinct forms of ulceration of joint-cartilages, i. 254; Wilson on inflammation of cartilage, i. 254; Hunter, Wilson, and Brodie, on the ulcerative absorption of, i. 254, 255; Lawrence on ulceration of cartilage as an original affection of the joints, i. 255; Key on the conditions under which ulcera- tion of the cartilages is effected, i. 255; Key on the absorption of cartilage by a new membrane produced by inflammation of the synovial membrane, i. 256; Key on the progress of ulceration in cartilage, i. 256; Goodsir holds with Key that the deposit from the synovial membrane is the cause of ulceration in cartilage, i. 257 ; accordance of Key's views with those of Wilson, i. 258; Key on the changes in the synovial membrane, when suppuration is the result of a wound in it, i. 258; they induce ulcerative absorption of the articu- lar cartilages, i. 258; Brodie does not ac- cord with Key's views, and considers that absorption of cartilage may take place under such circumstances as to admit of no other agrency than that of the vessels of the cartilage, i. 259 ; Lawrence's case of rapid ulceration of cartilage, i. 260; Lawrence on the necrosis of long bones as a cause of inflammation and absorption of cartilage, i. 260; Key on the formation of an adventitious membrane in joints under such circumstances, i. 261; this is a re- pairing process, preparatory toanchylosis, r. 261; Henle explains the absorption of cartilage from want of nutriment, l. 261; Key on ulceration of cartilage, an action altogether different from absorption, i. 261 ; Key on the process of ulceration generally, i. 261; Key on the process by which ulceration of the cartilage is effect- ed, i. 261; it leads to the formation of abscess, i. 262; post-mortem appearances, i. 262; Schumerand Gendrin never found any trace of inflammation in cartilage, i. 262; Brodie and South consider ulcera- tion of cartilages differs from common inflammation of the synovial membrane, and of the spongy ends of bones, i. 262; Brodie on the degeneration of cartilage into a fibrous structure, i. 2b3; this change Key describes as the third mode of ulcera- tion of cartilage, i. 263; causes of the disease, i. 263 ; Brodie on the period at which ulceration of the articular cartilages may occur, i. 264; prognosis always un- favourable, i. 264; treatment, i. 264; In- flammation of the joint-ends of bones, i. 264; symptoms, i. 264; Brodie on inflam- mation of the joint-ends of the bones, its symptoms and progress, i. 264; Brodie on the consequence of this inflammation, i. 264 ; Key on the two forms of disease in the bone, resultingin absorptionof the car- tilage, i. 265; the chronic form is of a strumous nature, i. 265; the acute form differs from the former in the suddenness of the attack, and in the appearance of the bone, i. 265; progress of the acute disease, and appearance of the bone, i. 265; Good- sir on the scrofulous disease of the cancel- lated texture of the heads of bone, i. 266 ; post-mortem appearances, i. 266; situation and causes of the disease, i. 266; Brodie and Key on the period at which itis likely to occur, i. 266; Brodie observes that it is likely to occur in several joints at once, or in succession, i. 266; Brodie and South's opinion that the occurrence of scrofulous disease in the joint has sus- pended the progress of some other and perhaps more serious disease elsewhere, i. 266; Brodie on the diagnosis between scrofulous disease of the joint-ends of bones and ulceration of the articular car- tilages, i. 267; prognosis and treatment, i. 267; favourable consequences of ulcera- tion of the cartilages, i. 267 ; may occur in one of two ways, i 267; in the first the cartilage is replaced by a layer of ivory-like bone, and the motions of the joint continue, i. 268 ; in the second, the opposed ends of the bones are united, either by a ligamento-fibrous structure or by bone, i. 268 ; South has seen the con- necting medium composed partly of liga- mento-fibrous, and partly of bony matter, i. 268; South on the ivory-like covering of the joint surfaces of bones, i. 268; Key 876 ANALYTICAL INDEX. and Toynbee on the removal of the arti- cular cartilages in old age, i. 26S; South and Brodie on the removal of the articular cartilages in old age as the result of pre- vious ulceration, i. 268; John Hunter on anchylosis, i. 268; anchylosis effected by the whole substance of the articulation, i. 268; of two kinds, i. 269; Hunter on the inflammatory and scrofulous diseases of joints causinganchylosis,i.269; Hunter on soft anchylosis from granulations, i. 269 ; Hunter on bonyanehylosis, i.269; South's views on anchylosis differ somewhat from those of Hunter, i. 269; South on soft anchylosis from granulations, i. 269; Key on the formation of a vascular membrane in joints as a preliminary to anchylosis, i. 270; South's case of fibrous anchylosis, i. 270; South's case of the complication of bony and fibrous anchylosis, i. 271; Hunter's case of soft anchylosis from the extension of inflammation from the sur- rounding parts to the joint, i.272; Mayo's caseof injury to the ankle, followed by ab- sorption of the cartilages, and effusion and organization of lymph between the ends of the bones, i. 273; process of bony anchy- losis, i. 274 ; the most important form of bony anchylosis, i. 274; Cruveilhier's case of bony anchylosis of the right con- dyle of the lower jaw, i. ^74; other kinds of anchylosis, i. 274; treatment of the soft or ligamento-fibrous anchylosis, i. 274; Velpeau on the treatment of complete anchylosis, i. 275; Barton's operation of cutting out a wedge-shaped piece of bone, i. 275; also performed by Gibson, i. 275; operation for the establishment of a false joint, i. 275 ; Velpeau favourable to this proceeding, i. 275; performed by Barton and Rodgers with success, i. 275; the operation of breaking through the anchy- losis, i. 275; condemned by Velpeau, i. 275; Amussat's case, i. 275; Velpeau on the consequences of the adhesion of the knee-pan to the condyle of the femur, i. 276; Louvrier's apparatus for the rup- ture of the anchylosis, i. 276; Velpeau's objections to the use of that apparatus, i. 276 ; hysterical affections of the joints, i. 277; Brodie on the symptoms of hyste- rical affections of the joints, i. 277; Tyr- rell on the diagnosis between inflamma- tion and hysterical affections of the joints, i. 277; Bell's case of hysterical affection of the hip-joint, i. 277; Coulson's case, i. 278; Coulson on the symptoms of this disorder, i. 278; Goodlad's objection to the term "hysterical" being applied to these affections, i. 278; South on the con- stitutional treatment of the disorder, i. 278; Brodie and Goodlad on the local ap- plications,!. 278; inflammation of the hip- joint (coxalgia,) i. 278; the three stages of the disease, i. 278; symptoms of acute inflammation of the hip-joint, i. 279; Key on the greater frequency of chronic than of acute inflammation of, i. 279 ; symp- toms when suppuration takes place,i. 279; symptoms of first stage of chronic inflam- mation of the hip-joint, i. 279; Brodie on ulceration of the cartilage, the primary affection in diseased hip, i. 280; Key's opinion that the ulceration of the cartilages is proceeded by inflammation of the liga- mentum teres, i. 280; South on the pain on the inside of the knee in hip- disease, i, 280 ; Bell and Coulson's ex- planation of that symptom, i. 280; symp- toms of the second stage of chronic inflammation of the hip-joint, i. 280; Astley Cooper on the second stage of hip disease, i. 280; Key on the symptoms which indicate the special part of the joint affected, i. 281; symptoms of the third stage, i. 281 ; Fricke's method of examining the length of the limb during the progress of the disease, i. 281; Astley Cooper and Coulson on the bursting of abscesses of the hip-joint, i. 282; Dr. Mackenzie and Scott's cases of abscesses of the hip-joint, i. 282; Brodie on the difference between hip disease from ulce- ration of the cartilage, and that from scro- fulous deposit in the cancellous structures of the bones, i. 282; shortening and lengthening of the diseased limb, i. 284; Hunter on these symptoms, i. 284; Cline and Lawrence on these symptoms, i. 284; the shortening only apparent, i. 284; Rust and Fricke's explanation incorrect, i. 284; South on the shortening of the limb, i. 284; the lengthening of the limb may be either seeming or real, i. 285; explanation of the lengthening of the limb by Petit, Camper, Valsalva, Monro, Van der Haar, de Haen, Vermandois, Schwenke, Calli- sen, Plenck, Portal, Ficker, Duverney, Clossius, Boyer, Falconer, Rust, Lan- genbeck, Richter, Schreger, Larrey, Che- lius, Fricke, Brodie, and Crowther, i. 283; Weber's experiments show that the head of the thigh-bone is retained in the socket by atmospheric pressure, i. 285; these experiments of great importance in reference to diseases of the hip-joint, i. 286; South's explanation of the lengthen- ing of the limb, i. 286; Astley Cooper on the lengthening of the limb from effusion into the joint, i. 286 ; Lawrence on the lengthening of the limb, i. 286 ; dislocation of the,head of the thigh-bone, i. 287 ; Nester, Van der Haar, Berdot, Schreger, and Textor on the dislocation ANALYTICAL INDEX. 877 of the head of the thigh-bone downwards j and inwards, i. 287 ; Hoffman's case of separation of the head of the femur, and its removal by the surgeon, i. 287; South on the appearances after death in hip dis- ease, i. 287; Earle on dislocation into the ischiatic notch, i. 287; Boyer, Bro- die, and Coulson on dislocation into the foramen ovale, i. 287; Ducros jun. on dislocation forwards on the share-bone, i. 287; the formation of a new socket, i. 287 ; Samuel Cooper on the substance which fills up the acetabulum, i. 287 ; diagnosis of coxalgia from congenital luxation of the thigh, shortening of the extremity from recession and twisting of the hip-bone, nervous sciatica, and ma- lum coxae senile, i. 288; coxalgia cannot well be confounded with phlegmasia alba dolens, psoas abscess, or primitive dis- location of the thigh, i. 289; may be con- founded with fracture of the neck of the thigh-bone under certain circumstances, i. 289; Bell on the pain in hip* disease, i. 289 ; South on the sympathetic pain in the hip from disordered bowels, i. 289 ; South, Smith, Wernherr, Astley Cooper, and Charles Bell on the morbus coxae senilis, i. 289 ; Coulson on the diagnosis between hip disease in the third stage, and psoas abscess, i. 2891; post-mortem appearances, i. 290; post-mortem appear- ances in William Adams' case, i. 290; etiology of hip-joint disease, i. 291; Fricke on the distinction between cox- algy and coxarthrocacy, i. 291;. prognosis always unfavourable, i. 291; treatment, i. 291; in the first stage of acute coxal- gia, i. 291; Coulson on salt-water bathing in hip-disease, i. 292; treatmentof chronic coxalgia, i. 292; Nicolai and Klein re- commend the use of the apparatus for fractured neck of the femur, i. 292; Phy- sick on the treatment of coxalgia, i. 292; Scott's plan of treatment, i. 293; Law- rence's observations on the plan of treat- ment advocated by Scott, i 293; has been employed by Fricke with advan- tage, i, 294; treatment of the second stage, i. 294; application of the actual cautery, i. 294; Rust objects to the use of issues, i. 294; approved of by South, i. 294; the actual cautery on burning cylinders preferable in all cases where the limb is much lengthened, the muscles j relaxed, and where there is great swell- ing from collection of fluid, i. 294; Volpi has not found benefit from the actual cautery, when the first symptoms of dis- ease occurred in the knee, and not at the hip-joint, i. 294 ; Brodie on the influence of the primary irritation of the issue, and on the maintaining it by repeated appli- cations of caustic potash and sulphate of copper, i. 295; approved of by South, i. 295 ; Duval's local steam-bathing appa- ratus, i. 295; Brodie on the use of a seton in the groin, i. 295; results of the treat- ment, and management of convalescence, i. 296; Rust and Brodie on warm bathing, i. 296; Fritz, Rust, and Jaeger on the mercurial treatment, i. 296; Brodie on the importance of restand position, i. 296; general treatment in the first two stages of coxalgy, i. 297; Jaeger, Rust, Dieffen- bach, and Frank on the general treatment of coxalgy, i. 297 ; Fricke's plan, i. 297; treatment of the consecutive dislocation, 297; reduction of the dislocation fre- quently not successful, i. 297 ; views of PetitjCallisen, and Jaeger on the reduction of consecutive dislocation, i. 297; cases by Berdot, Hagen, Ficker, Thilenius, Mozilewsky, Schneider, B Heine, F. Humbert, M. N. Jacquier, Textor, Volpi, Schreger, von Winter, Harless, Fricke, and J. Heine, i. 297, 298; treatment of suppuration, i. 298 ; the abscesses to be freely opened, 298; Ford, Wend, Van der Haar, Rust, Brodie, and Jaeger on the treatment of these abscesses, i. 298; Sabatier and Ficker advise their being opened with caustic, i. 298; Larrey, with the red-hot trocar, i. 298 ; Rust, with the actual cautery, i. 298; Rust advises pass- ing a seton through the joint, i. 299; Bredie and Jaeger recommend free inci- sions in opening these abscesses, i 291; Brodie and South on the management of abscesses-at the hip, i. 299; subsequent treatment, i. 299'; resection of the carious head of the thigh-bone, i. 299 ; excision of the head of the femur recommended by Jaeger, Kirkland1, Richter, and Verman- dois, i. 299; performed by White and Hewson, i. 299"; Kerr and Baffos exarti- culated the thigh*bone, i. 299>; Charles Bell's proposition, h 299 ; Barry's case of accidental reduction' of the dislocation, i. 299; inflammation of the shoulder- joint—omalgia, \. 300; three stages of the disease, i. 300; symptoms and re- sults, i. 300; dislocation-of the head of the bone, i. 300; abscesses and' caries- of the bone, i. 301; post-mortem; appear- ances, i. 301; etiology, prognosis, and treatment, i. 301; inflammation of the knee-joint (gonalgia), i. 301 ; symptoms and progress, i. 301; difference between rheumatic and scrofulous white swelling of the knee-joint, i. 301; post-mortem appearances, i. 302; South and Brodie on the diagnostic symptoms of the diseases of the knee, i. 302; Brodie on ulceration 878 ANALYTICAL INDEX. of the cartilages, i. 302; Rainey oa a pe- culiar degeneration of the cartilage in disease of, i. 303; Brodie on scrofulous disease in the cancellated structure of the bones of, i. 304; progress of caries, i. 304 ; white swelling, i. 304; application of the term, i. 304; the disease very fre- quent in Great Britain, but rare in Italy, Vienna, and many other parts of Ger- many, i. 3.05.; Russell and Gotz on the appearances of white swelling on dissec- tion, i. 305; Nicolaion the symptoms and progress of white swelling, i. 305; Nicolai on the anatomy of white swelling, i. 306 ; prognosis and treatment, i. 307 ; inflam- mation in the joints of the vertebrae (Pott's disease), i. 307; locality and symptoms of the disease, i. 308; curving of the spine, i. 308; Pott on the symptoms and progress of the disease, i. 308 ; caries of the verte- brae, the cause of curvature of the spine, i. 308 ; connexion of the disease with lumbar and psoas abscess, i. 308; Law- rence and Brodie on the curvature from caries, i. 308; Pott on the so-called palsy pf the limbs, i. 309 ; Brodie onthe occur- rence of suppuration in caries of the ver- tebrae, i. 309; Brodie on the disappear- ance of psoas abscess, and its appearance elsewhere, i 309; Brodie on the pain in vertebral caries, i. 309; Brodie on the extent of the curvature in dorsal caries, i. 309; post-mortem appearances, i. 310 ; Brodie, Key, and Lawrence on the patho- logy of spinal caries, i. 310;. Brodie on chronic inflammation of the vertebrae, with ulceration of the intervertebral car- tilage, i. 311; causes of the disease, i. 311 ; diagnosis and prognosis, i. 311 ; diagnostic signs of the disease, accord ing to Copland, Wenzel, Stiebel, Melker, and South, i. 311 ; South, Lawrence, and Brodie on the diagnosis between curva- ture of the spine from caries and that from rickets, i. 312 ; treatment of the disease, i. 313;; Brodie on the applicability of issues in this disease, i.. 313; Astley Cooper, Lawrence, and Brodie on the manner in which the disease is cured by anchylosis, i; 314; symptoms of the disease in the cervical vertebrae, i. 315; Brodie and Astley Cooper on vertebral caries in tho neck, i. 315; Brodie on abscess connected with vertebral caries in the neckv i. 315 : post-mortem appear- ances, i. 316 ; symptoms and progress, of the disease in. the sacro-iliac synchon- drosis, i. 31G. Joints, Wounds of, i. 536; symptoms, i. 536; probing the wound objectionable, i. 537; danger of joint-wounds, i. 537; Hun- ter on the suppurative inflammation of wounded joints*i, 537; Astley Cooper on wounds of joints, and their results, i. 537; treatment, i. 537 ; Astley Cooper's treat- ment of wounded joints by a fine suture, i. 53H ; Abernethy's practice, i. 538; com- mended by South, i. 538; treatment of the accompanying inflammation, i. 538 ; of the suppuration, i. 538 ; cases requiring amputation, i. 539; gunshot-wounds of the joints, i. 539. Joints, Unnatural, ii. 13; definition, ii. 14; John Hunter on the formation of false joints, ii. 14; causes, ii. 14; Brodie, Gibson, and Amesbury on the formation of a false joint, with a fibro-ligamentous capsule, and a lining membrane, ii. 14 ; false joints most frequent in the upper arm, ii. 14; Amesbury, South, and Astley Cooper on the causes of the non-union of fractured bones, ii. 14; Macmurdo'scase of false joint of the humerus, ii. 15; treatment of false joints, ii. 15; John Hunter on the treatment of false joints, ii. 15; rubbing the ends of the broken bone together, ii. 15; Celsus, Boyer, and South on rubbing the ends of the broken bone together, ii. 15; Cittadini's case, ii. 16; pressure, ii. 16 ; application of pressure, ti. 16; application of blisters, caustic potash and tincture of iodine, ii. 16; South on the application of pressure in false joints, ii. 16; South objects to ex- ternal irritation, ii. 17; application of strong caustics to destroy the cartilagi- nous surfaces on the ends of the bones, by OHenroth,Clinejun.,Hewson,Weilinger, and Kirkhide, ii. 17; Mayor and Hulse's plans of treatment, ii. 17 ; White, Cline, Lehmann, and Barton's cases of cure of ununited fractures, ii. 17; Cline jun. and Hewson's eases of cure by the application of caustic potash to the broken ends of the bones, ii. 17 ; the operation of sawing off the cartilaginous ends of the fractured bone, ii. l~t; Dupuytren, Pigne, and Brodie on this operation, ii. 18 ; Guy de Chaujiac's account of this operation, as practised by the Arabian physicians, ii. 18; Charles White and Lawrence on sawing off ihe ends of the broken bone, ii. 18; Green's operation on an ununited fracture of the femur, ii. 19; South's re- marks on this case, ii. 19; the introduc- tion of a seton, ii. 20 ; Weinhold, Oppen- heim,, and Jobert. oa the introduction of the seton, ii. 20; danger attending the use of the seton in oblique fracture, ii. 20; Physick on the use of the seton, ii. 20; Fricke and Cittadini's operations for saw- ing off the ends of the fractured bones successful, ii. 20. Joints, cartilaginous bodies in,.iii. 443; am- putation through, yL 686„ Jonas on puncturing the distended intestine ANALYTICAL INDEX. 879 after the operation for strangulated her- nia, iii. 107. Jqnks' experiments on the ligature of ar- teries,!. 335; on the application of the liga- ture, ii. 492; on the effects produced by the ligature on the arterial coats, ii. 493. Jones, H. Bence, on the formation of uri- nary calculi, iii. 237; on the phosphatic diathesis, iii. 247; on the treatment of uric acid gravel, iii. 259; on the treat- ment of the oxalic diathesis, iii. 261; on the treatment of the phosphatic diathesis, iii. 264. Jones', Dr. Wharton, description of the phenomena of inflammation under the microscope, i. 41 ; on exudation, i. 45 ; on the process of union by adhesion, i. 322; on healing by the second intention, or granulation, i. 326. Jorg's apparatus for keeping the head straight in wry-neck, ii. 423; on the in- fluence of spinaJ curvature on the trans- verse diameter of the pelvis, ii. 427. Josse's apparatus for fracture of the neck of the femur, i. 623. Joubert on the acarus scabiei, ii. 66. Jourel's case of puncturing the womb in retroversion, ii. 412., Judd on hydriodate of potash in syphilis, ii. 101. Junod's apparatus to cause derivation of the blood, ii. 101. Kaltenbrunner on the formation of new vessels, i. 324, Kayser on the statistics of the Caesarian operation, iii. 157. Keate's operation for stone in infants, iii. 297; case of chimney-sweep's cancer on the cheek, iii. 560. Keckely's apparatus for fractured clavicle, i. 603. Keith's, Dr., case of vesico-vaginal fistula cured by a calculus in the bladder acting as a valve to prevent the discharge of the urine, ii. 197. Kellie's, Dr., remarkable case of exposure to cold, i. 145. Kendrick on the treatment of haemor- rhage consecutive to the extraction of a tooth, ii. 141. Kennedy's case of gunshot wound on the right side of the thyroid cartilage, i. 482; case of bands in the vagina, iii. 90. Kentish's plan of treatment of burns, i. 130; mode of application of stimulants, i. 130; disapproval of frequent dressings, i. 130. . . , Kern on the application of caustic for the radical cure of hernia, ii. 283 ; on ligature of the protruded omentum at the abdomi- nal ring for the radical cure of rupture, ii. 283; operation for stone in women, in. 352; mode of amputating at the knee with the flap-cut, iii. 699. Ker's case of procidentia uteri treated with the secale cornutum, ii. 379. Kerr's mode of amputating at the hip-joint by the circalar cut, iii. 689. Kerst's mode of operating in excision of the ankle-joint, iii. 743. Key on ulceration in ligamentous fibre, i. 233 ; on the conditions under which ul- ceration of the cartilages takes place, i. 255; on the absorption of cartilage by a new membrane produced by inflammation of the synovial membrane, i. 256; on the progress of ulceration in cartilage, i. 256; accordance of his views with those of Wilson, i. 258 ; on the changes in the synovial membrane, when suppuration is the result of a wound in it, i. 258; they induce ulcerative absorption of the arti- cular cartilages, i. 258 ; on the formation of an adventitious membrane in joints, in cases of necrosis of the long bones, when it causes inflammation and absorption of the cartilages, i. 261; this is a repairing process preparatory to anchylosis, i. 261; on ulceration of cartilage, an action alto- gether different to absorption, i. 261; on the process of ulceration generally, i. 261; on the process by which ulceration of cartilage is effected, i. 261; it leads to the formationof abscess, i. 262; describes the degeneration of cartilage into a fibrous structure as a third mode of ul- ceration, i. 263; on the two forms of dis- ease in bone, resulting in absorption of the cartilage, i. 265; the chronic form is of a strumous nature, i. 265; the acute form differs from the chronic in the com- parative suddenness of the attack, and in the appearance which the bone presents, i. 265; on the period at which the in- flammation in the joint-end of the bones is likely to occur, i. 266 ; on the removal of the articular cartilages in old age, i. 268 ;■; on the formation of a vascular membrane in joints, as a preliminary to anchylosis, i. 270i; on the greater fre- quency of chronic than of acute inflam- mation of the hip-joint, i. 279; is of opi- nion that the ulceration of the cartilage in hip disease is preceded by inflamma- tion of the ligamentum teres, i. 280,289; on the symptoms which indicate the spe- cial part of the joint affected, i. 281 ; on the pathology of spinal caries, i. 310; on the propriety of active, general, and local depletion in strangulated omental hernia, prior to the operation, ii. 272; on the re- duction en masse, ii. 274; advises the unfolding the omentum before cutting it off, ii. 300 ; on abscesses in the sac oc- 880 ANALYTICAL INDEX. casionally reproducing the symptoms of strangulation, ii. 301 ; on the operation of dilating the abdominal ring, without opening the sac, ii. 302; views with re- gard to this operation, ii. 303; on the siorns indicative of gangrene of the intes- tine, ii, 305; case of gangrenous intes- tine, in which a fetid smell was percep- tible before the sac was opened, ii. 306; on suppuration of the sac, ii. 306; case of sloughing of the intestine after its return into the abdomen, ii. 309 ; on the occurrence of gangrene in the intestine some days after the operation, in persons of an enfeebled constitution, ii. 310; on the fatal termination of cases after the operation, when preceded by great de- pression, ii. 311; case of strangulated in- guinal rupture, the testicle being at the external ring, ii. 324; on the seat of strangulation in femoral rupture, ii. 335 ; on the operation for femoral rupture, ii* 337; on the post-mortem appearances in a case in which he tied the subclavian twelve years previously, ii 524; mode of operating for stone in the bladder, iii. 313; on suppurative inflammation of the cellular tissue surrounding the bladder, the most frequent cause of death after lithotomy, iii. 340; on the advantages and applicability of lithotrity, iii. 357 ; on lithotrity with reference to the size of the calculus, iii. 358; on, the appli- cability of lithotrity or lithotomy, ac- cording to the age of the calculous pa- tient, iii. 358; on the requisite con- dition of the bladder for the operation of lithotrity, iii 358 ; on irritability of the bladder, iii. 358; case of sarcomatous scrotum, iii. 548; case of exarticulation of metatarsal bones, with the diseased bones of the tarsus, iii. 710. Kidneys, wounds of, i. 527; nature, symp- toms, and treatment, i. 527; stone in, iii. 265. Kilian on the application of the suture in vesico-vaginal fistula, ii. 192. Kino on artificial anus at the umbilicus, connected with the diverticulum ilei, ii. 158; on ligature of the innominata, ii. 522; on the extirpation of the ovary, iii. 210; case of extirpation of the ovary, iii. 211. Kirby on the effects of the scorpion sting, i. 387; cases in which severe symptoms followed the use of the ligature in piles, ii. 584; on tracheotomy in croup, iii. 115. Kirkbridk on the use of caustic to destroy the ends of the broken bone in false joints, ii. 17. Kirkland, Dr., advises to let lumbar or psoas abscess break of itself, i. 213; re- commends the resection of the carious head of the femur in hip-disease, i. 300; on the arrest of haemorrhage by nature, i. 329. Kleberg on congenital dislocation of the knee, i. 248. Klein recommends the use of the appara- tus for fractured neck of the femur in the treatment of hip disease, i. 292; on the exhibition of prussic acid in tetanus, i. 419; apparatus for fracture of the neck of the femur, i. 624; on the treatment of prolapse of the rectum, ii. 401; on sound- ing the bladder, iii. 277; operation for the division of the middle branches of the facial nerve, and of the infra-orbitar nerve, iii. 633; operation for dividing the facial nerve, iii. 633; operation for di- viding the inferior maxillary nerve, iii. 634; operation for destroying the trunk of the facial nerve at its exit from the stylo-mastoid foramen, iii. 634 ; the ope- ration performed in two cases without a permanent cure, iii. 634; considers it to be entirely free from danger, iii. 635; objections to the upper flap in partial amputation of the foot, iii. 705. Klimatis on the solution of the chloride of lime in the treatment of foul, gangrenous, or torpid ulcers, ii. 44. Kluge's plan of treating lymph abscesses, i. 106; torsion-apparatus, i. 342; appara- tus for fracture of the lower jaw, i. 580; bandage for fractured clavicle, i. 603; method of replacement of the dislocated femur, i. 239, 401. Knee-cap, fracture of, i. 630; dislocation of, ii. 247. Knee-joint, dislocation of, ii. 248; curva- tures of, ii. 443; exarticulation of the leg at, iii. 699 ; excision of, iii. 739. Kohler on the torsion of bony vessels, i. 344; experiments on the excision of joints, iii. 727. Kolletscha on the formation of new ves- sels, i. 324. Koppenst^dter's apparatus for fractured clavicle, i. 603; fracture-bed, i. 625. Kramer's case of excision of the heads of metatarsal bones, iii. 744. Krause on the existence of itch without eruption, ii. 64; on the microscopic cha- racters of medullary fungus, iii. 458. Krimer on the removal of the edges of the cleft in staphyloraphy, ii. 31; plan for bringing the edges of the cleft together, ii. 32; operation when the cleft is very large and complicated, ii. 33; on the operation of amputation at the hip-joint, iii. 688. Kuh's operation for varicocele, ii. 578. ANALYTICAL INDEX. 881 Kuhl's case of ligature of both carotids, ii. 508. Labarraque on the solution of the chloride of lime in the treatment of foul, gangre- nous, or torpid ulcers, ii. 44. Labat's case of bands in the vagina, iii. 89; modification of the Indian method of rhinoplasty, iii. 584. Labia, abscess of, i. 180; enlargement of, iii. 399. Lacerated and contused wounds. See Wounds. Lacroix on the nervous symptoms attend- ing sudden retroversion of the womb, ii. 409. Laennec on the membrane of the fistulous passages, i. 108; on the physical charac- ters of dropsy of the pericardium, iii.201; on the division of tumours, iii. 381 Lafond, Jalade, on the reduction of con- genital dislocation of the femur, ii. 245 ; pad with a reservoir for caustic, used for radical cure of hernia, ii. 282. Lalle»iand on iodine in hard swellings of the testicles, ii. 100 ; on the appearances presented on post-mortem examination, some time after the cure of artificial anus, ii. 155; on cauterization as a means of cure in vesico-vaginal fistula, ii. 190; on the application of sutures in vesico-vagi- nal fistula, ii. 193; caustic holder for stricture of the urethra, iii. 83; on the treatment of complete retention of urine in stricture, iii. 145 ; on the operation for cutting into the urethra in the perinaeum, iii. 147; on the retention of the catheter in the urethra, iii. 150. Lampe's artery compressor, i. 331. Langenbeck's opinion on the lymph- swelling, i. 61; on the treatment of fis- tulous passages by ligature, i. 109; treat- ment of long fistulae in the breast, i. 171; condemned by South, i. 172; on the lengthening of the limb in hip-disease, i. 285; artery-compressor, i. 331; onjiydro- phobia as caused by a qualitative altera- tion of the blood by the poison, i. 410; employs trepanning in injuries of the head only when secondary symptoms of irritation and pressure require it, i. 454 ; on the treatment of fractured patella, i. 632; on the nature of strangulation in rupture, ii. 269; on increased pressure and the supine posture in the radical cure for hernia, ii. 282;'on ligature of the her- nial sac for its radical cure, n. 283; on excision of the prolapsed and scirrhous womb, ii. 382; on ligature of the external iliac, ii. 538 ; operation for division of the inner fold of the prepuce, m. 58 ; on the ligature of the carotid, prior to the extir-, pation of the parotid, iii. 525 ; operation for amputation of the penis, iii, 545; case of extirpation of the cancerous womb, iii. 569, 570; operation for the division or excision of the facial nerve at the stylo- mastoid foramen, iii. 635; operation for flap amputations, iii. 642; mode of ampu- tating the thigh with two flaps, iii. 659 ; mode of amputating at the hip-joint with the flap-cut with a single flap, iii. 691; objections to the upper flap in partial am- putation of the foot, iii. 705; mode of operating in exarticulation of the meta- tarsal bone of the great toe, iii, 709; in amputation at the shoulder-joint, iii. 714; mode of operating in exarticulation of the metacarpal bones of the ring and little fingers, iii. 721, Langius on mortification from spurred rye, i. 74. Langlet's case of a ball remaining in the brain for eighteen months, i. 439. Langstaff's case of a madman who swal- lowed a silver spoon, iii. 104; on tu- mours of nerves of stumps, iii. 506. Larrey's, Baron, plan of treating burns, i. 129; on the effects of frost-bite, i. 145; observations on the effects of too suddenly warming a frozen or benumbed limb, i. 148; on the lengthening of the limb in hip-disease, i. 285; on opening abscesses at the hip with the red hot trocar, i. 298 ; on the union of the nerves of a stump in loops, i. 365; on amputation in tetanus, i. 419 ; on the removal of foreign bodies in injuries of the brain, i. 438; case of loss of memory after concussion, i. 450; on the subsequent effects of the closure of the opening in the skull after trephining, i. 467; case of excision of a portion of a rib for the removal of a ball, i. 490; practice in wounded intestine, i. 509; on the treat- ment for compound fractures, i. 561; on the immoveable apparatus in fractured ribs, i. 599; on inversion of the foot in fracture of the neck of the femur, i. 618 ; apparatus for fracture of the neck of the femur, i. 623; on the internal opening of reetal fistula, ii. 162; moxa of rotten phosphorescent wood, iii. 631; case of amputation through the head of the tibia, iii. 670; mode of amputating at the hip- joint with two flaps, iii. 692; at the shoulder-joint, iii. 714; operation for the excision of the head of the humerus, when fractured by a musket-shot, iii. 717; case of excision of part of ihe hand, iii. 722; on excision of joints, iii. 727. Larrey's, H., cases of regular shaped gun- shot wounds, iii. 373. Laryngotomy, iii. 115. Laryngo-tracheotomy, iii. 120. 882 ANALYTICAL INDEX. Larynx, fracture of the cartilages of, ii. 581; wounds of, i. 475; foreign bodies in, iii. 109. Laserre's apparatus for fractured clavicle, i. 603. Latour's case of accumulation of blood in the womb, and rupture of the organ, ii. 530. Latta on tapping lumbar or psoas abscess with a trocar, and passing a seton through the abscess afterwards, i. 212; his prac- tice condemned by South, i. 212. Lawrence's cases of malignant pustule, i. 78 ; on sloughing phagedena, i. 83 ; on incisions in pseudo-erysipelas, i. 125; op- posed to the treatment of erysipelas by moderate compression, i. 125; case of alarming hemorrhage from puncturing an immature tonsillar abscess, i. 162; on the hemorrhage following the extirpation of the tonsils, i. 166; on gonorrhoea be- nigna and virulenta, i. 182; on gonor- rhoea virulenta, i. 183; on lumbar abscess generally connected with carious verte- brae, i. 209; supports Abernethy's treat- ment of lumbar abscess, i. 213; on the diagnosis of fluctuation in synovial in- flammation, i. 240 ; on hydrarthrus or hydrops arliculi, i. 241; on the pulpy degeneration of the synovial membrane, i. 255; on ulceration of cartilage as an original aff'ection of the joints, i. 255; case of rapid ulceration of cartilage, i. 260; on the necrosis of long bones as a cause of inflammation and absorption of carti- lage, i. 260; on the lengthening and shortening of the affected limb in hip- disease,!. 284, 286 ; observations on the plan of treatment advocated by Scott in hip-disease, i. 293 ; on curvature of the spine from caries, i. 308; on the patho- logy of spinal caries, i. 310 ; on the diag- nosis between curvature of the spine from caries, and that from rickets, i. 312; on the manner in which the disease is cured hy anchylosis, i. 314; objection to the term " inflammation " in reference to union by adhesion, ii. 323 ; on the after-manage- ment of the ligature on arteries, i. 338 ; on the absorption of poisonous matter in dissection wounds, i. 384; details of Dr. Pen's case, i. 386; on the fatal effects of the stings of bees and wasps, i. 387; case of hydrophobia, i, 403 ; on the com- munication of hydrophobia from one human being to another, or from man to beasts, i. 403 ; on the peculiar delirium of hydrophobia, i. 407; on a costive state of the system preceding tetanus, i. 416; on the proximate cause of tetanus, i. 417; case of pistol-shot wound of the brain, i. 438 ; on puncturing the dura mater to evacuate effused blood, i. 448; on bleeding from the tongue from bites made during a fit, i. 471; cases of partial or complete dislocation of the spine, i. 587; case of complete dislocation of the fourth from the fifth cervical ver- tebra, i. 587; occurrence of vertebral dislocation specially in the neck, i. 588; case of fracture of the os calcis, i. 639 ; sawing off the ends of the broken bone in false joints, ii. 18; on the period at which the operation for hare-lip should be performed, ii. 23; on the use of scis- sors with knife-edges in the operation, ii. 23; on the sutures in the operation for hare-lip, ii. 25; on the progress of syphilis from one part of the body to another, ii. 71; on the progress of ulce- ration in a syphilitic sore, ii. 72 ; on the five kinds of syphilitic sores, ii. 73 ; on the four kinds of* syphilitic eruptions, ii. 78; on the exhibition of mercury in cases of chancre, and on the rarity of the occurrence of secondary symptoms when mercury has been used, ii. 87; on the extent to which the use of mercury may be pushed, ii. 87; case of a syphilitic child infecting the nurse, ii. 105; on syphilitic iritis and ulceration about the anus in infants, ii. 106; on the possibility of infection from secondary syphilis, ii. 106 ; on the combined effects of mercury and syphilis in the production of the mer- curial disease, ii. 103; definition of caries, ii. 114; on the treatment of caries, ii. 118; case of necrosis from irritation, i- 120; on the terms "necrosis" and "exfolia- tion," 124 ; on salivary calculi, ii. 150; on the appearances presented on post- mortem examination some time after the cure of artificial anus, ii. 156 ; on Du- puytren's operation for artificial anus, ii. 158; on dislocations from muscular action, ii. 159; on the double hernial sac, ii. 261; on the statistics of rupture, ii. 26; on the nature of strangulation, ii. 269; on the reduction en masse, ii. 274; objections to operations for the radical cure of her- nia, ii. 289; modification of Petit's opera- tion, ii. 304; ascribes the fatal result after the operation for strangulated hernia, not to the exposure of the parts to air and light, but to the protracted constriction to which they have been subjected, ii. 305; recommends opening thesacand dividing the stricture from within, ii. 307; on the statistics of wounds of the epigastric or obturator artery in operations for femoral rupture, ii. 342; case of fatal hemorrhage from a wounded branch of the epigastric, ii. 342; case of successful operation for strangulated umbilical ruptures during ANALYTICAL INDEX. 883 pregnancy, ii. 346; case of rnpture of the I rations for the extirpation of the ovary, recti abdominis, ii. 348; on thyroid rup-l iii. 213. ture, ii. 352; on the symptoms of internal \ Leeches, application of, iii. 612. strangulation, ii. 359; on the bruit de souf flet, ii. 472 ; on the effects, produced by the ligature on the arterial coats, ii. 493; on Brasdor's operation, ii. 504; on the peculiar noise heard in an aneurismal varix, ii. 549 ; on the application of the ligature in teleangiectasy, ii. 562; on the spongy excrescence of the rectum, iii. 45; on stricture of the rectum, iii. 46; on the use of bougies in stricture of the rectum, iii. 50; on the use of bougies armed with caustic potash in stricture of the urethra, iii. 80; on the use of the armed bougie, iii. 84; case of the neck of a wine-bottle in the rectum, iii. 109; cases of worms and larvae discharged from the urethra, iii. 134; on catheterism in inflammation of the prostate, iii. 137 ; on chronic en- largement of the prostate, iii. 139; on the treatment of enlarged prostate, iii. 142 ; on the treatment of retention of urine from enlarged prostate, and on cathe- terism in such cases, iii. 143; on the tran- sition between new or accidental produc- tions and changes of structure, and de- generations of organs, iii. 379; case of very large fatty tumor, iii. 427; case of cellular membranous tumors, iii. 448 ; case of amputation just above the ankle, iii. 675. Lawrence, John, on the immoveable ap- paratus for fractures, i. 553. Lawrie, Dr., on the part played by the dead bone in necrosis in the process of reproduction, ii. 128; on the cause of the difficulty experienced in reducing dislo- cations of the thumb from the metacarpal bone, ii. 235; on the use of the actual cautery in prolapsus uteri, ii. 379 ; on the results of amputation,iii. 656 ; objections to amputation below the knee, iii. 675. Leacock's case of fatal phrenic rupture, ii. 358. Leber's artery-compressor, i. 331; on the stanching the bleeding from an inter- costal artery, i. 492. Leblanc on incision of the hernial sac, etc., for its radical cure, ii. 283 ; on dilatation of the stricture in strangulated hernia without cutting, ii. 298. Lecat on dilatation of the stricture in strangulated hernia without cutting, ii. 298; mode of operating for stone, iii. 324. Lee, Dr. Robert, on inflammation of the femoral and iliac veins, an occasional cause of phlegmasia dolens, i. 95. Lee, Stafford, on the statistics of the ope- Leg, fracture of the bones of, i. 635; arti- ficial, iii. 593; amputation through, iii. 668; exarticulation of, at the knee, iii. 699. Lehmann's case of cure of ununited frac- ture, ii. 17 ; operation for varicocele, ii. 578. Lemaire on the solution of the chloride of lime in the treatment of foul, gangrenous, • or torpid ulcers, ii. 44. Lembert's practice in wounded intestine, i. 509; approved of, i. 509; Dupuytren's modification of, i. 515. Lenoir on the causes of varicocele, ii. 577; on dropsy of the bursae in the sole of the foot, iii. 181 ; mode of amputating through the leg in its lower third, iii. 670; mode of amputating at the hip- joint with the flap-cut with the single flap, iii. 692. Lentin on neuralgia of the heel, treated by deep incisions, iii. 636. Leroy d'Etiolles on the statistics of the operations for cancer, iii. 510. Leucorrhea distinguished from gonor- rhea, i. 180; Dr. Locock on leucor- rhea, i. 180; characters of the secretion, i. 180; Locock and Jewel on the distin- guishing signs between leucorrbcea and gonorrhoea, i. 181. Lesenberg's plan for bringing the edges of the cleft together in staphyloraphy, ii. 32. Lewin's, Dr., experiments on colchicum as a cause of an increased production of uric acid in the urine, ii. 55. Lewis on the treatment of hydrocele by punctures, iii. 224. Liber on the torsion of arteries, i. 341. Lieber on torsion of arteries, ii. 501. Lieutaud on incision of the hernial sac, etc., for its radical cure, ii. 283. Ligaments, Inflammation of. See Inflam- mation of the Joints. LiGHTFOOT'scaseof prolapse of the bladder, in which he performed the operation of episioraphy, ii. 396. Limbourg's, De, case of wound of the head with a ramrod, i. 471. Lingual artery, ligature of, ii. 513. LinnjEus on the acarus scabiei, ii. 67. Lips, cancer of, iii. 515. Liordat's emporte-pieee, ii. 158. Lisfranc's plan of treating burns with a so- lution of the chlorate of lime, i. 129; on the use of the stethoscope in the diag- nosis of fractures, i. 545 ; case of fracture of the os calcis, i. 640; on the solution of chloride of lime in the treatment of foul, gangrenous, or torpid ulcers, ii. 884 ANALYTICAL INDEX. 44; case of reduction of an old dislocation of the elbow-joint, ii. 231; on the cause of the difficulty experienced in reducing dislocations of the thumb from the meta- carpal bone, ii. 234 ; on the relative fre- quency of aneurism in the sexes, ii. 475; on the relative frequency of aneurism in the arteries, ii. 475; on the ligature of a diseased artery, without opening the sheath, ii. 496; on the section of the sca- lenus anticus in ligature of the subclavian, ii. 518; on ligature of the external iliac, ii. 538 ; vestibular cut in lithotomy in wo- men, iii. 351; operation for cancer of the corpora cavernosa, iii. 547; operation for scirrhous cervix uteri, iii. 567; case of fatal haemorrhage from leech-bites, iii. 635; mode of amputating at the hip-joint with two flaps, iii. 692; in exarticulation of the metatarsal bones, iii. 706; at the shoulder-joint,iii. 713; modification of the operation when performed prior to the age of fifteen, iii, 717; mode of operating in exarticulation of the hand at the wrist, iii. 720; on exarticulation of the middle and ring fingers, iii. 723 ; flap-operation of the fingers, iii. 723. Liston's account of the hospital gangrene in University College Hospital in 1841, i. 82 ; on the formation of new vessels, i. 324; adhesive plaster, i. 360; mode of operating in staphyloraphy, ii. 33 ; on epulis,ii. 136 ; case of speedy reduction of a dislocated femur, ii. 203; on the mode of reducing dislocation of the thumb from the metacarpal bone, ii. 235; on the causes of splay-foot, ii. 457 ; on compression in the treatment of aneurism, ii. 486; case of ligature of the subclavian above the clavicle, ii. 519; on spontaneous aneu- rism of the brachial, ii. 528; on ligature of the arteries of the fore-arm, ii. 528; on the peculiar noise heard in an aneurismal varix, ii. 549; case of aneurismal varix in the femoral vein and artery, ii. 549; on the seat of stricture in the rectum, iii. 46 ; case of foreign body in the bronchus, in which tracheotomy was performed, and the foreign body extracted with for- ceps, iii. 118; case of partial solution of a stone in the bladder, iii. 280 ; on the dila- tation of the female urethra, iii. 283 mode of operating for stone in the bladder iii. 350; operation for stone in women, iii 350 ; on the incontinence of urine conse quent on lithotomy in women, iii. 353; on the breaking or bending of lithotritie instruments in the bladder, iii. 356 ; on the cases in which lithotrity should be performed, and on those in which litho- tomy should be preferred, iii. 360; cases of a small brass ring encircling the penis, iii. 363; case of sarcomatous tumor of the scrotum, iii. 449; on tumors of nerves, iii. 506; case of sarcomatous scrotum, iii. 550; operation for raising a sunken nose, iii. 591; on the use of the saw in amputa- tions, iii. 643; preference of the flap ope- ration, and objections to the circular ope- ration, iii. 0.33; mode of amputating through the thigh by the flap operation, iii. 600; account of eighteen amputations through the thigh, iii. 661 ; mode of am- putating through the leg with two flaps, iii. 673 ; statistics of amputation through the leg, iii. 675 ; statistics of amputation through the upper arm, iii. 679; cases of amputation through the fore-arm, iii. U>2; on amputation through the metacarpal bones, iii. 666; mode of amputating at the hip-joint with two flaps, iii. 0y2 ; case of amputation at the shoulder-joint, iii. 71? ; mode of operating in excision of the lowerjaw, iii. 753; mode of operating in resection of the upper jaw, iii. 756; on the prospect of ultimate success in this operation in cases of malignant disease, iii. 761 ; case of resection of the scapula, iii. 762; employment of ether by inhala- tion prior to the performance of impor- tant surgical operations, iii. 76?. Literature of surgery, i. 21. Lithotrity, iii. 2»5. Lithotomy, iii. 296; recto-vesical lithotomy, iii. 344 ; lithotomy in the female, iii. 34?. Lithectasy, iii. 375. Little, Dr., on the diagnosis between club- foot and the deformity of the tarsus caused by rickets, ii. 447 ; case of amputation of the thigh, with the flap behind, iii. 660. Littre's mode of operating in ovarian dropsy, iii. 206. Lizars on the large operation for ovarian dropsy, iii. 212; the first to recommend the entire removal of the upper jaw, iii. 755 ; description of the proposed opera- tion, iii. 755; casein wThich he attempted to perform the operation, but failed on account of the haemorrhage which ensued, iii. 756 ; cases in which he performed the operation, iii. 756. Liver, wounds of, i. 525; symptoms, i. 525; danger of such wounds, i. 525; Astley Cooper on stabs of the liver, i. 525; South on rupture of the liver, i. 525 ; treatment, i. 525 ; wounds of the gall bladder, i. 525; consequences of such wounds, i. 525; symptoms of effusion of bile into the cavity of the abdomen, i. 525; Hoering and Emmert's experi- ments on the injection of bile into the cavity of the peritoneum, i. 526 ; Dupuy- tren's experiments, i. 526; case of ANALYTICAL INDEX. 885 wounded gall-bladder quoted bv Goech, i. 526. J Locher on vesicles on the spleen in hydro- phobia in dogs, i. 409. Locock, Dr., on leucorrhea, i. 180; cha- racters of the secretion, i. 180; on the distinguishing signs between leucorrhea and gonorrhea, i. 181; on pudendal dis- charges in females during dentition, i. 181 ; case of bands in the vagina from previous difficult labour, iii. 89 ; case of spontaneous rupture of the ovarian cyst, iii. 214. Lode on two kinds of curvature of the hand, ii. 464. Loeffler on puncturing the distended in- testine after the operation for strangulated hernia, ii. 298. Lonnes', Imbert de, case of sarcomatous tumour of the scrotum, iii. 449. Lorch on the effects of torsion, i. 343. Lordosis, ii. 428. Lottery on stanching the bleeding from an intercostal artery, i. 492. Louis on the rotation of the foot outwards in fracture of the neck of the femur, i. 618 ; on the reduction en masse, ii. 274 ; case of a foreign body remaining a long while in the windpipe, iii. 112; mode of amputation by the circular incision, iii. 640. Louvrier's apparatus for the rupture of anchylosis, i. 276 ; Velpeau's objections to its use, i. 277; on the more general application of the trephine, i. 454; on the friction cure in syphilis, ii. 94. Lowe on puncturing the distended intes- tine after the operation for strangulated hernia, ii. 298. Lugol on iodine in scrofula, ii. 51; for- mulae for the exhibition of iodine, ii. 51; dispute with Alibert on the acarus sca- biei, ii. 67. Luke on the use of the ligature in rectal fistula, and on the mode of operating, ii. 168 ; on the dilatation of a strangulated rupture on coughing, ii. 270 ; on reduc- tion en masse, ii. 275; on the signs indi- cative of reduction en masse, ii. 276 ; on the operation required when reduction en masse has occurred, ii. 277 ; description of the operation for dividing the stricture external to the sac, ii. 307; on the diag- nosis of the seat of stricture, ii. 307 ; on incision of the sac, or on partial division of its neck in several places, when the stricture is caused by it, ii. 308; case of resection of the scapula, iii. 762. Lumbar muscles, inflammation of; lum- bago, psoitis :—seat of the inflamma- tion, i. 207; symptoms, i. 207; forma- tion of abscess, i. 207; general symptoms Vol hi.—75 of suppuration not present if the abscess be not large, i. 208; this disease not what is usually called " lumbago," but psoas or lumbar abscess, i. 208; Astley Cooper on the symptoms of psoas abscess, i. 208; Pearson on the symptoms preceding and accompanying the formation of the ab- scess, i. 208; causes, i. 208; English surgeons generally consider disease of the vertebrae to be the cause, i. 206 ; Pott on the diseased condition of the spine in this complaint, i. 208 ; Astley Cooper on the origin of psoas or lumbar abscess in in- flammation of the spine and intervertebral substance, i. 209; Abernethy, Lawrence, and Dupuytren on lumbar abscess gene- rally connected with carious vertebrae, i. 209 ; South on the origin of the disease from external violence, its seat then being in the spine, i. 209; South on the dis- tinctive characters of psoas abscess from femoral hernia, i. 209; John Pearson on the situation of the external abscess, i. 210; Samuel Cooper's notice of Rams- den's case of lumbar abscess, i. 210; treatment of inflammation of the lumbar muscles, i. 210 ; South on the insidious progress of the disease, i. 210 ; abortive treatment of lumbar abscess, i. 211 ; opening the abscess, i. 211 ; Dupuytren on the changes that sometimes take place in the abscess, i. 211; Astley Cooper re- marks that the abscess must be allowed to take its course, i. 211; this opinion con- troverted by South, i. 211; Cline and Abernethy's experiments to cause the ab- sorption of the pus, i. 211; South on issues in the treatment of lumbar or psoas abscess, i. 211 ; difference of opinion as to propriety of wasting the self-evacuation of the abscess, or of puncturing and emptying it, either entirely or partially, i. 212; Deckers, Benjamin Bell, and Crowther on tapping the abscess with a trocar, i. 212; Latta recommends the use of a seton in addition, i. 212 ; this latter practice condemned by South,who prefers opening the abscess with a lancet, i. 212 ; Abernethy's plan of treatment, i. 212; Astley Cooper and Lawrence support Abernethy's views, i. 213 ; Kirkland ad- vises to let the abscess break of itself, i. 213; John Pearson prefers making a small aperture, and treating the ulcer in a very gentle manner, i. 213; Dupuytren leaves the abscess to nature, i. 213; South's plan of treatment, i. 213 ; treat- ment to be pursued after the abscess is opened, i. 213; Pearson and Astley Cooper on the treatment of the sinuous cavities resulting from the abscess by in- jections, i. 214; Dupuytren recommends 886 ANALYTICAL INDEX. cauterization or weak injections of nitrate i of silver, or nitric acid, i. 214 ; treatment of the abscess, if inflammation supervene, after it has been opened, i. 214 ; Aber- nethy on the symptomsof the supervening inflammation, i. 214; Pearson mentions that the larger arteries sometimes ulce- rate into the abscess, i. 214 ; M'Dowell mentions a case in which ulceration took place in a portion of the ileum adhering to the cyst of the abscess, i. 214. Lungs, wounds of, i. 483, 485 ; See Wounds of the Chest. Lupus, or herpes exedens, ii. 58. Lynn's performance of the Taliacotian ope- ration, iii. 577. Macaulay's case of phrenic rupture, de- pending on malformation of the dia- phragm, ii. 356. McClellan, Dr. on the cause of broncho- cele, iii. 389; on bronchocele as a variety of scrofula, iii. 389; case of resection of the scapula and clavicle together,iii. 764; McCormac, Dr., on careful traction of the skin in prolapse of the rectum, ii. 404. M'Dowall, Dr., on the large operation for ovarian dropsy, iii. 212. M'Dowell mentions a case in which ul- ceration took place in a portion of the ileum adhering to the cyst of a lumbar abscess, i. 214. Macgill's case of ligature of both carotids, ii. 507. McGrigor, Sir James, on the period of the accession of tetanus after the receipt of the injury, i. 415. Mackenzie's, Dr., case of abscesses of the hip-joint, i. 282. Mackintosh, Dr., on an epidemic vaginal catarrh, i. 182. McLaughlan's, Dr., case of a large plug of wood in the rectum, iii. 107. Macmurdo's case of rupture of a vessel in the penis during coition, i. 178; case of secondary haemorrhage in cut throat, i. 476; case of false joint of the humerus, ii. 15; case of aneurismal varix between the internal jugular vein and carotid artery, ii. 546; case of cellular membranous tumor, iii. 449. Macrae's case of a foreign body in the bronchus, iii. 118. McSweeny, Dr., on the silk-worm gut ligature, i. 339. Magendie's experiment on the communi- cability of hydrophobia from man to man, and from man to beasts, i. 403; case of hydrophobic patient biting another person, i. 407; on the formation of urinary cal- culi, iii. 237 ; on hairy gravel, iii. 256; on the treatment to be adopted when air i enters a vein during an operation, iii. 603 ; on the cause of death from entrance of air into a vein, iii. 603; on the injec- tion of warm water into the veins in hy- drophobia, iii. 626. Maiden's case of penetrating wound of the chest, i. 483. Maingault's mode of amputating at the knee with the flap cut, iii. 699 ; mode of operating in partial amputation of the foot, iii. 705. Malagodi's case of excision of a portion of the ischiatic nerve in the region of the knee-joint, iii. 636. Malgaigne on the local treatment of frac- tured ribs, i. 599 ; on the frequency of dislocation in the different joints, ii. 202. on the primitive direction of dislocation of the humerus, ii. 221 ; case of reduction of an old dislocation of the elbow, ii. 230; on the cause of the difficulty experienced in reducing the dislocation of the thumb from the metacarpal bone, ii. 235; on the seat of strangulation in ruptures, ii. 268; case of resection of the fibula, iii. 767. Mammary, internal, ligature of, ii. 525. Mandt on the chemical and microscopic characters of pus, i. 46 ; on the pus-glo- bules, i. 53 ; on the presence of globules in the serum, i. 56. Manec on the introduction of a piece of bougie into an ossified artery after ampu- tation, i. 336; on ligature of the inno- minata, ii. 522; mode of amputating at the hip-joint by the flap-cut with a single flap, iii. 693. Manovy's case of division of the posterior tibial nerve, iii. 636. Marcet, Dr., on the premonitory pains of hydrophobia, i. 408 ; case of knife-swal- lowing, iii. 115. Marchetti's case of swine's tail in the rectum, iii. 109. Marjolin on excision of the prolapsed and scirrhous womb, ii. 381. Marochetti on the presence of pustules under the tongue after the bite of a mad animal, i. 413; plan of treatment pro- phylactic of hydrophobia, i. 413 ; views objected to by Watson, i. 414. Marshall on the application of flour in cases of burns, i. 133. Martin on the causes of club-foot, ii. 446. Martineau's cases of very small urinary calculi, iii. 273; operation for stone in the bladder, iii. 317. Martin^re's, Dela, case of a foreign body in the windpipe, iii. 110. Mauchart on incision and scarifications of the hernial sac, for its radical cure, ii. 283. Maunoir on the effects produced by the ligature on the arterial coats, ii. 493 ; on ANALYTICAL INDEX. 887 the ligature of the spermatic artery in va- ricocele, ii. 578; treatment of bronchocele by puncture and irritating injections, and by seton, iii. 397; on simple serous cysts of the neck, iii. 432; on the chemical con- stituents of the brain-like substance in medullary fungus, iii. 458; on ligature of Med1n on the stanching the bleeding from the spermatic artery in sarcocele, iii-1 an intercostal artery, i. 492. Maun'sell's, Dr., description of noma, jMeding's experiments on incomplete frac- 75; on the suppuration of mumps, i. 169 ; | ture' K 544' on t{?e Production of callus, on the communication of syphilis to the1 u foetus in the womb, ii. 106; on the 8ymp-i Mbddli-a**' Fungus, iii. 453; characters, bral rupture, ii. 365 ; on the influence of spinal curvature on the transverse diame- ter of the pelvis, ii. 427; on the division of tumours, iii. 382; opinion that melano- sis is the same as medullary fungus, iii. 462. toms of syphilis in infants, ii. 106 ; on its treatment, ii. 106. Mauriceau on the operation for the treat- ment of lacerated perineum, ii. 39 ; on the application of the sutures, ii. 39. Maxillary sinus, disease of, iii. 478 ; bone, lower, fracture of, i. 579; excision of, iii. 715 ; upper, resection of, iii. 784; frac- ture of, i. 579; artery, external, ligature of, ii. 514. Mayo describes the occasional occurrence of pus-globules in healthy blood, i. 53; case of injury to the ligaments of the knee, i. 230; describes three distinct forms of ulceration of joint-cartilages, i. 254 ; case of injury to the ankle, followed by absorp- tion of the cartilages, and effusion and organization of lymph between the ends of the bones, i. 273 ; on the progress of caries, ii. 115; on inflammation as the cause of caries, ii. 117 ; on the treatment of caries, ii. 118; on the application of caustic in varix, ii. 573 ; on haematocele, iii. 175 ; on dropsy of the bursae mucosae, iii. 178; on the formation of bursae from pressure, iii. 178 ; case of large calculus, iii. 273 ; on tumours of nerves in stumps, iii. 506. Mayor's treatment of fractured clavicle, i. 603; treatment of false joints, ii. 17; on the sutures in the operation for hare-lip, ii. 25; operation for the radical cure of hernia, ii. 285 ; on extirpation of broncho- cele by ligature, iii. 398; on ligature of the neck of the womb, iii. 567 ; on ampu- tation of the phalanges with the tachy-1 tome, iii. 686. Mead, Dr., on viper's fat as a local remedy in viper's bite, i. 390 ; case of the bite of a rattlesnake, i. 390; experiments on viper- poison, i. 391; on the protraction of the period of incubation in hydrophobia, l. 404; on the increase of muscular strength in hydrophobia, i. 408. _ Meckel on the vessels of cartilage, i. 252 ; on the three kinds of union of divided parts—quick union, by adhesion, and by granulation, i. 319 ; on the causes of cere- bral rupture, ii. 365 ; case of cure of cere- iii. 454; symptoms and situation, iii. 455; medullary fungus of the testicle, iii. 455; symptoms and termination, iii. 455; of medullary fungus of bone, iii. 457; Astley Cooper on medullary fungus of bone, iii. 457; appearances of the parts on dis- section, iii. 457; chemical examination of the brain-like substance, iii. 457; Hecht, Maunoir, and Muller on the chemical constituents of the brain-like substance, iii. 458 ; Krause on the microscopic cha- racters of medullary fungus, iii. 458; Gluge on the nature of, iii. 458 ; me- dullary fungus occasionally encysted,iii. 458; characters of the brain-like sub- stance in medullary fungus of the testicle, iii. 459 ; characters of medullary fungus, iii. 459; Allan Burns and von Walther on the difference between fungus haematodes and sarcoma medullare, iii. 460; Aber- nethy on fungus haematodes, iii. 460; Muller on the applicability of the term "medullary fungus "to the different forms of soft cancer, iii. 461; Vogel on the essential element of medullary fungus, iii. 461; Bradley, Jaeger, and Vogel on the blood fungus, iii. 461; Meckel's opinion that melanosis is the same as medullary fungus, iii 462; this opinion only par- tially correct, iii. 462 ; diagnosis between medullary fungus and scirrhus, iii. 463 ; Breschet's different kinds of carcinoma, merely different degrees of development of medullary fungus, iii. 464; Abernethy's sarcoma tuberculatum considered by Meckel to be medullary fungus, iii. 464 ; this opinion incorrect, iii. 464; etiology of medullary fungus, iii. 464 ; diathesis fungosa, iii. 464; seat and mode of forma- tion of medullary fungus, iii. 464; treat- ment of the disease almost entirely inef- fective, iii. 464 ; early ablation of the part or amputation of the limb affords the only chance of cure, iii. 465; the disease generally returns sooner or later, iii. 465. Meig:s plan of treatment in ingrowing of the nail by a compress and linen-roller, i. 223. 888 ANALYTICAL INDEX. Melier's apparatus for dislocation of the clavicle forwards, ii, 219. Melker's diagnostic sign for vertebral caries, i. 312. Melle's case of dislocation of the scapular end of the clavicle downwards, ii. 220. Mendaga on the hydrarg. cyan, in syphilis, ii. 93. Mende on the seeming retroversion of the womb at the latter periods of pregnancy, ii. 409. Menzel on the operation for the treatment of lacerated perineum, ii. 39. Mercier's opinions on the changes which the substance of the bone undergoes in advanced age, i. 545 ; on inversion of the foot in fracture of the neck of the femur, i. 618; on the characters of horns, iii. 403; on the treatment to be adopted when air enters a vein during an operation, iii. 604. Mercurial disease, ii. 107. Merrem, Dr., on wounds of the uterus, as predisposing to rupture in subsequent la- bours, i. 53.1 ; explanation of this fact, i. 531. Mery on incision of the hernial sac and the introduction of lint tents for its radical cure, ii. 283. Mesenteric and mesocolic ruptures, ii. 358. Metacarpal bones, amputation through, iii. 682; exarticulation of, at the carpus, iii. 721 ; excision of, iii. 722. Metacarpus, excision of the joints of, iii. 744. Metastatic abscesses, i, 48. Metatarsal bones, amputation through, iii. 682; exarticulation of, iii, 706 ; excision of, iii. 723; fracture of the bones of, i. 615. Metatarsus, excision of the joints of, iii. 744. Mettauer, Dr., on the operation of staphy- loplasty by granulation, ii. 27. Meyer on the application of nitric acid to the scar of nerves, i. 364; apparatus for fracture of the neck of the femur, i. 624 ; case of strictured oesophagus communi- cating with the left bronchus, iii. 28; case of resection of the clavicle, iii. 764. Michaelis on the treatment of gonorrhoea, i. 197; on the operation for the ingrowing of the nail, i. 224; on the division of the tendo Achillis in club-foot, ii. 453; on the doubtful character of the old cases in which the Caesarian operation is reported to have been performed several times successfully on the same woman, iii. 157; case in which the operation was per- formed four times on the same woman, iii. 157; on the danger attending the effu- sion of the secretions from the wound into the belly, iii. 162; on the exhibition of opium, and on the necessity of keeping the bowels open after the operation, iii. 162 ; on the greater probability of success attending the repetition of the operation, than in the first instance, iii. 164. iescher on the ossification of arteries, i. 91; says nodilference between permanent cartilage, and that which is to be con- verted into bone, i. 249; differs in opinion with W. Hunter respecting the fibrous structure of articular cartilage, i. 249; on the production of callus, i. 545 ; sum- mary of views on the formation of the primary and secondary callus, i. 54.5; experiments to induce suppuration in compound fractures, i. 559; summary of experiments to ascertain the processes under which suppurating fractures are united, i. 566; on the granulations attend- ing caries, ii. 114; on the characters of caries, ii. 115; on the seat of various kinds of caries, ii. 117; on the signs of exfoliation, ii. 125; on the absorption of part of the dead bone in the process of exfoliation, ii. 126; on the process of cicatrization after necrosis, ii. 128. Mirault's operation for the ligature of the tongue, iii, 521. Mobus' case of vertebral aneurism, ii, 527. Model's opinion that spurred rye does not cause gangrene in beasts, i. 74; disproved by Tessier, i. 74; Block's experiments on the subject, i. 75. Mohrenheim's apparatus for fracture of the patella, i. 633. Moj'sisovic's equilibrium plan in fracture of the femur, i. 629. Moller's case of gangrene of the penis, from the constriction of a metal ring, i. 534. Monnier's, Le, operation of staphyloraphy, ii. 31. Monro on the lengthening of the limb in hip-disease, i. 285; slippers for rupture of the tendo Achillis, i. 542; on the ap- plication of caustic for the radical cure of hernia, ii. 283; on the dilatation of the abdominal ring, the hernial sac being unopened, ii. 303 ; cases of half-pence in the oesophagus, iii. 97; case of a foreign body in a sac behind the oesophagus at its origin, iii. 97. Montain on the operation for the treatment of lacerated perineum, ii. 39 ; on the ap- plication of the sutures, ii. 39. Monteiro's case of ligature of the aorta, ii. 532. Montgomery, Dr., on the origin of scirrhus uteri in the ova Nabothi, iii. 562; case of cancer uteri, iii. 563. Morand on the arrest of haemorrhage by ANALYTICAL INDEX. 889 nature, i. 329; on the extirpation of the ovary, iii. 210; mode of amputating at the shoulder-joint with the circular cut, iii. 715. Moreau's case of excision of a joint, iii. 726; on the excision of joints, iii. 726 ; statistics of cases, iii. 727; mode of ope- rating in excision of the head of the humerus, iii. 732; in excision of the elbow-joint, iii. 733 ; on the division of the ulnar nerve in excision of the elbow- joint, iii. 733; mode of operating in ex- cision of the knee-joint, iii. 740 ; on the mode of union after the operation, iii. 740; mode of operating in excision of the ankle-joint, iii. 741. Morere's case of abscess of the womb, i. 532. Morgagni on the causes of varicocele, ii. 577. Morgan's opinions relative to the formation of pus, i. 46; on the reduction of the dis- located femur by placing the foot between the thighs, and making extension and rotation, ii. 242; case of a pouch formed at the mouth of the tunica vaginalis, ii. 262. Morris', Dr., case of injurious effects pro- duced by the inhalation of ether, iii. 769. Mortification:—divided by Chelius into the hot and cold, i. 66;- Travers' objection to the terms mortification andisphacelus, i. 66; definition of mortification, i. 66; 8ymptoms,i.67; Travers' acute gangrerie, i. 67; destruction of the mortified parts occurs either as dry, moist, or hospital gangrene, i. 67; South on. vesications filled with a bluish or bluisb>black fluid in cases of severe bruise, or when the bandages in cases of fracture are too tight, i. 68; causes of mortification, i. 68; Brodie on sudden loss of blood, a cause of mortification, i. 68; Travers on deep and extensive effusion, and' on injuries of nerves, as causes of mortification, i. 68; South's case of mortification of the lower extremity from effusion of blood causing distention of the limb, i. 68; mortification in cases of aneurism caused by distention from teffusion, i. 69 ; mor- tification in cases of simple fracture, the principal artery of the limb being un- injured, i. 69; South's cases of mor- tification after fever, i. 69», senile gan- grene, i. 69; distinction between senile gangrene consequent on injury, and that resulting from constitutional causes, 1.71; Travers' chronic gangrene, i. 72; causes of dry gangrene, i. 72; South's case of dry gangrene consequent on abdominal typhus, i. 72; Dupuytren on arteritis a cause of dry gangrene, i. 72, 89; South s 75* case of dry gangrene from organic disease of the heart, i. 72; Brodie's case of dry gangrene from inflammation of the prin- cipal artery and vein of a limb, i. 72; Brodie on the cause of the distinction between dry and moist gangrene, i. 72 ; gangrene from arterial inflammation a comparatively rare disease, i. 73; this statement denied by Cruveilhier and Dupuytren, i. 73; South's case of arteritis without gangrene, i. 73 ; Solly's case of gangrene, i. 73 ; mortification from con- tinued pressure, i. 74; mortification from the use of the cock-spurred rye, i. 74; Thomson's account of this form of the disease, i. 74 ; Sigebert and Bayle's re- marks, i. 74; the disease first noticed by Dodard, afterwards by Saviard, Noel, Langius, Quassoud, Bossau, and Duha- mel, i. 74 ; Elliotson's case of gangrene of the leg after the use of ergot, the arte- ries of the limb being also ossified, i. 74; Model's opinion that spurred rye does not cause gangrene in beasts, i. 74; disproved by Tessier, i. 74; Block's experiments on the subject, i. 75; Dr. C. Woolaston's cases of gangrene, i. 75; mortification of the cheek, called noma by Vogel, i. 75; a rare and generally fatal disease, i. 75; description of noma by Drs. Evanson and Maunsell, i. 75; the term, cancrum oris, incorrectly applied to noma, i.- 76; can- crum oris, a form of mortification com- mencing with ulceration, generally first in the gums, and thence spreading to the lips and cheeks, i. 76;. described by Dr. Gumming, is 76; South's case of noma in the adult, i. 76; mortification, a con- sequence of contagious influence, results in malignant pustule, or hospital gan- grene, i. 77; malignant pustule, its causes and symptoms, i. 77 ; contagious from beasts to man, but not from man to man, i. 77 ; Elliotson on glanders in the human subject, u 78; Lawrence's cases of malignant pustule, i. 78; Beer's and Delpech's-cases, i. 79; Turchetti's cases of malignant pustule, described by him as anthrax, i. 79 ; Dr. Wagner's cases of malignant pustule, produced by contact, and by; eating the flesh of diseased ani- mals, L. 80;-Dr. Bourgeois' observations on malignant pustule, L-81; hospital gan- grenej i. 82; description of the disease, i. 82; local and general symptoms, i. 82; Liston's account of the hospital gan- grene in University College Hospital in 1841, i. 82; Arnott's cases of hospital gangrene at the Middlesex Hospital, i. 83; the disease exceedingly rare in the London hospitals-, i. 83; Lawrence on sloughing phagedena, i. 83; Welbank 890 ANALYTICAL INDEX. on sloughing phagedena, i. 84 ; this dis- ease regarded by S. Cooper as resem- bling hospital gangrene, i. 84; denied by South, i. 84; South on the sloughing state of stumps from want of power, i. 84; the characteristic of hospital gan- grene, i. 84 ; the cause of hospital gan- grene is the operation of a peculiar con- tagious matter, i. 84; it is always a very dangerous complication of wounds and sores, i. 84; treatment of gangrene, i. 109 ; when connected with active inflam- mation, and inflammatory fever, mode- late antiphlogistic treatment to be em- ployed, i. 110; if caused by the constric- tion of unyielding aponeuroses, they must be divided, i. 110; when connected with general debility, tonics and mineral acids indicated, i. 110; local treatment of gangrene, i. 110; if there be active in- flammation, soothing poultices : if the part be free from pain, and shrivelled, stimulant applications required, i. 110; remedies which prevent the influence of the grangrenous juices, i. 110 ; their ac- tion aided by scarifications in the gan- grenous parts, i. 110; these latter must not penetrate into the living parts, i. 110; scarifications are dangerous in gangrena senilis, i. Ill; amputation not applicable in gangrene depending on an internal cause still in operation, i. Ill; applicable after the line of demarcation has formed, or in gangrene from external violence, even while still proceeding, i. Ill; South's opinion that amputation should never be performed while the gangrene is in progress, i. Ill; treatment of senile gangrene, i. Ill; when resulting from an injury, soothing or. dry aromatic ap- plications, or leeching, if the inflamma- tion be active, i. Ill; Dupuytren em- ployed the antiphlogistic plan of treat ment in plethoric subjects, i. Ill; when from constitutional causes, tonics and opium necessary, i. 111 ; treatment of gangrene from pressure, i, 112 ; from the use of spurred rye, i. 112 ; Thomson and S. Cooper's cases, i. 113; treatment of malignant pustule, i. 113; local treat- ment by cutting out the pustule, and cauterizing the wound, i. 113 ; if the pustule not deep, but. the slough much spread, deep scarifications and the appli- cation of caustic recommended, i. 113; employment of constitutional treatment, i. 113 ; treatment of hospital gangrene, i. 113; emetics advised by Routeau and Dussausoy, i. 113; washing the sore with vinegar or solution of arsenic in the commencement of the disease, i. 113; the entire surface to be touched with nitrate of silver, i. 114; the free applica- tion of the actual cautery most effectual, i. 114; constitutional treatment should be employed at the same time, i. 114; gan- grenous destruction of parts from burns, i. 126; treatment of mortification caused by burns, i. 129; cold wet sufficient to induce mortification, if continued suffi- ciently long to reduce the natural heat below a certain standard, i. 144; gan- grene the result of too suddenly warming a frozen limb, i. 147; treatment of a frozen part in which mortification is threatened, from its having been too has- tily warmed, i. 148; when mortification has taken place, it must be treated in the usual manner, i. 148; treatment of gan- grenous chilblains, i. 149; gangrene of the testicle a rare termination of inflam- mation, i. 201; causes and treatment of mortification in compound fractures, i. 558; South on mortification in compound fractures, and its treatment, local and general, i. 560 ; sloughing of the omen- tum in strangulated hernia, ii. 301; gan- grene of the intestine in strangulated hernia, ii. 302. Morton on the inhalation of ether prior to the extraction of teeth, iii. 767. Moscati on the extirpation of the tonsils by cutting, i. 164. Moseley's, Dr., case of scorpion sting, i. 357; on the chigoe, i. 388. Mothe on the primitive direction of dislo- cation of the humerus, ii. 221. Mott on the treatment of fistula of the rectal sheath, ii. 169; on the operation for tying the innominata, ii. 521; opera- tion for the ligature of the common iliac, ii. 533; mode of amputating at the hip- joint with two flaps, iii. 692; case of ex- cision of part of the side of the lower jaw, without the condyle, iii. 748; mode of operating in excision of the lower jaw with the condyles, iii. 749; on the pre- vious ligature of the carotid artery, iii. 750; case of articulation of one side of the lower jaw, iii. 751; case of resection of the clavicle, iii. 764. Motte, La, on the operation for the treat- ment of lacerated perineum, ii. 39; on the application of the sutures, ii. 39. Mouffet on the acarus scabiei, ii. 66. Mouth, narrowing and closing of, iii. 24; foreign bodies in the, iii. 94. Moxas, application of, hi- 631. Mozilewsky's case of reduction of the consecutive dislocation in hip-disease, i. 297. Mulder's mode of operating in excision of the knee-joint, iii. 740; in excision of the ankle-joint, iii. 742. ANALYTICAL INDEX. 891 Muller on inflammation, i. 34; comparison Nasal bones, fracture of, i. 577. of the effects of heat and cold on the Nasse's case of lymph-swelling from ex- body, l. 144; on the vessels of cartilage, ii. 253; on tire causes of necrosis, and on the process of regeneration, ii. 120; on the production of new bone after necro- sis, ii. 127; on the division of tumors, iii. 381; on enchondron, iii. 409; on the varieties of fatty tumors, 427; on the chemical constituents of the brain-like substance in medullary fungus, iii. 458; on the applicability of the term " medul- lary fungus" to the different forms of soft cancer, iii. 461; on the four several kinds of carcinoma, iii. 498; on carcinoma simplex et fibrosum, iii.498; on carcinoma reticulare, iii.498; on carcinoma alveolare, iii. 498; on carcinoma fasciculatum, iii. 498; proposal to separate the fibrous part of the blood prior to transfusion, iii. 628. Munzenthaler's mode of operating in ex- articulation of the metatarsal bones, iii. 707. Murray's, Dr., case of ligature of the aorta, ii. 531. Mursinna on the more general application of the trephine, i. 454 ; on the treatment of fractures of the neck of the femur, i. 624; on the operation for the treatment of lacerated perineum, ii. 39; on the primitive direction of dislocation of the humerus, ii. 221. Muscles, lacerations of, i. 542. Mussey's, Dr., case of ligature of both ca- rotids, ii. 507; on the treatment to be adopted when air enters a vein during an operation, iii. 604; case of resection of the scapula and clavicle together* iii. 764. Mutter's plastic operations for the relief of deformities from burns, i. 142; on the period at which the operation for hare-lip should be performed, ii. 23; on the ad- vantage of operating early in hare-lip and cleft-palate, ii. 26; on the treatment of cleft-palate after the operation for hare-lip, ii. 27; on the use of obturators in cleft-pal ate, ii. 27; on the operation of staphyloplasty by granulation, ii. 27; successful operation in a case of loss of substance in the hard palate from chronic mercurial disease, ii. 28. Mynors' mode of amputating by the circu- lar incision, iii. 640. Naegele on the use of the suture in vesico- vaginal fistula, i. 190, 191. Naegele's, jun., case of womb at the eighth month of pregnancy, ruptured by exter- nal violence, i. 532. Nannoni on amputation at the shoulder- joint, with the circular cut, iii. 715. ternal injury, i. 61; on injecting a solu- tion of neutralized nitrate of mercury into a cold abscess, i, 105. Naumburg on the causes of club-foot, ii. 446. Neck, wounds of the, i. 473; nature of the wounds, i. 473; Astley Cooper on wounds of the throat, i. 473; deep penetrating wounds, with injury of the large vessels, i. 473; Travers' case of suicidal wound of the lingual or facial artery near its origin, with unsuccessful ligature of the common carotid, i. 473.; injuries of the pneumo-gastric nerve, i. 475; of the re- current nerve, i. 475.; of the laryngeal nerve, i. 475 ; Dupuy's experiments on the division of both pneumogastric nerves, i. 475; injury of the sympathetic or phrenic nerve, or of the spinal marrow, i. 475; wound of the windpipe, i. 475; loss of voice in large wounds of the wind- pipe, i. 475; Hennen on emphysema in wounds of the windpipe, i. 475; treatment of transverse wounds of the windpipe, i. 475; Fricke on the treatment of severe wounds of the neck, i. 476; South on po- sition in the treatment of wounds of the windpipe, i. 476; South on the treatment of such wounds, i. 476; treatment of the. general symptoms accompanying such wounds, i. 476.; subsequent treatment, i. 476; South on the treatment of such wounds, when there is much inflamma- tion, i. 477; South's case of fistulous wound between the thyroid and cricoid cartilages, i. 477; Astley Cooper's case of fistulous opening in the thyroid car- tilage, i. 477; South on secondary he- morrhage in cut throat, i. 477; Macmur- do's case, i. 477; stabs of the windpipe, i.477; bruised wounds of the larynx and windpipe, i. 478; shot-wounds with loss of substance, i. 478; South on the ma- nagement of the resulting fistula, i. 478; wounds of the gullet, i. 478; signs and treatment, i. 478; the oesophagus-tube, i. 478 ; Astley Cooper's objection to the use of the tube, i. 478; Stark's case, i. 478 ; Dr. Ryan's case, i. 479 ; Hennen's case of wound of the larynx and< oeso- phagus, i. 480; healing of wounds of the gullet, i. 480; stabs of the gullet, i. 480; deep wounds at the back of the neck, i..480; Hennen's case of severe nervous symptoms following gunshot wound, of the throat, i. 480; Kennedy's case of gunshot wound of the right side of the thyroid cartilage, i. 481. Necrosis, ii. 120; definition and divisions, ii. 120; situation, ii. 120; causes, iL 120; 892 ANALYTICAL INDEX. Muller on the causes of necrosis, and on the process of regeneration, ii. 120; Brom- field and Lawrence's casesof necrosis from irritation, ii. 120; symptoms, ii. 120; John Hunter on the ossific inflammation pre- ceding necrosis, ii. 121; diagnosis, ii. 121; distinguishing characters of caries and necrosis, ii. 122; separation of the dead bone as sequestrum, ii. 123; the processes of exfoliation, and of compensation for the dead bone, ii. 124; the reproduction of bone not dependent on the periosteum, ii. 124; Lawrence on the terms " necrosis "j and " exfoliation," ii. 124; Weinhold's objection to the term " exfoliation," ii. 124; John Hunter on the process of exfo- liation, ii. 124; John Hunterand Miescher on the signs of exfoliation, ii. 125; Mie- scher and South on the absorption of part of the dead bone in the prOcessof exfolia- tion, ii. 126 ; Troja on the incipient pro- duction of new bone after necrosis, ii. 126; Weinhold on the cloacae in necrosis, ii. 127; Muller on the production of new bone, ii. 127; Lawrie on the part played by the dead bone in the process of repro- duction, ii. 128; Miescher on the process ■of cicatrization, ii. 128; John Hunter on the species of exfoliation, ii. 128; prog- nosis, ii. 129 ; cases of necrosis indirectly affecting the joints, and requiring ampu- tation, ii. 130; Porter's case of wound of the popliteal artery by a sequestrum, ii. 130; treatment, ii. 130; separation and removal of the sequestrum, ii. 131; treat- ment in cases of necrosis of old standing, ii. 131; cases in which amputation is in- dicated, ii. 131. Negrier on fresh walnut leaves, and their decoction in scrofula, ii. 53. Nelken's, Dr., instrument for applying the ligature in rectal fistula, ii. 169. Nember on the exhibition of purgatives in strangulated hernia, ii. 291. Nephrotomy, iii. 267. Nerves, division of, in neuralgia, iii. 632. Nester on the dislocation of the.head of the thigh-bone downwards and inwards in hip-disease, i. 287. Neuralgia, division of nerves in, iii. 632. Nevermann on the stanching the bleeding from an intercostal artery, i. 492 ; mode of operating, i. 492; treatment of lacerated perineum, by cauterizing with unslaked lime, and afterwards by position, ii. 40; statistics of tracheotomy in laryngitis and tracheitis, iii. 115. Nicolai recommends the use of the appara- tus for fractured neck of the femur in the treatment of hip-disease, i. 292; on the symptoms and progress of white swelling, i. 305; on the anatomy, of white swell- ing, i. 306; apparatus for fracture of the neck of the femur, i. 624. Niel on gold and its preparations in pri- • mary and secondary syphilis, ii. 100. Nipples, inflammation and fissure of. See Inflammation of the Breast. Noel on mortification from spurred rye, i. 74; on the operation for the treatment of lacerated perineum, ii. 39 ; on the appli- cation of the sutures, ii. 39. Noma. See Mortification. Nose, double, Hi. 597; nose-making, iii. 575. Nostrils, growingtogetherand narrowing of, iii. 22; foreign bodies in the, iii. 94. Nuck on ligature of the hernial sac for its radical cure, ii. 283; on the diverticulum of the peritoneum in the female, ii. 328. Nymphae, abscess of, i. 181. Nysten on the cause of death from the en- trance of air into a vein, iii. 603. O'Beirne, Dr., on the fatal character of tetanus, i. 419 ; on the introduction of a thick elastic tube through the rectum into the sigmoid flexure of the colon in stran- gulated hernia, ii. 291; case of simple serous cysts of the neck; iii. 432. O'Bryen's case of displacement of the heart, ii. 361. O'Callaghan's, Dr., case of the lodgment of a foreign body in the frontal sinuses, i. 435. Occipital artery, ligature of, ii. 515. OS'sophagotomy, iii. 99. QEsophagus, wounds of, i. 478; stricture of, iii. 25; foreign bodies in the, iii. 95. Oesterlen's observations on the re-break- ing a badly united fracture, i. 576; ap- paratus for re-breaking the bone, i. 576, O'Ferrall's, Dr.,case of sarcomatous scro- tum, iii. 551. Ogle's case of puncturing the dura mater to remove the effused blood, i. 447. Olecranon, fracture of, i. 615. Oliver's case of fatal haemorrhage from leech-bites, iii. 614. Ollenroth on the use of caustic to destroy the ends of broken bone in false joints, ii. 17; modes of operating in ovarian dropsy, iii. 210. Ollivier on dislocation of the femur di- rectly downwards, ii. 237. Omalgia, inflammation of the shoulder- joint, i. 299; three stages of the disease, i. 299; symptoms and results, i. 299; dislocation of the head of the bone, i. 300; abscesses and caries of the bone, i. 300; post-mortem appearance, i. 300; etiology, prognosis, and treatment, i. 300. Onsenoort's, van, plan to prevent the needles tearing out after the operation for ANALYTICAL INDEX. 893 hare-lip, ii. 26; on the treatment of hy- drocele by seton, iii. 228; mode of ampu- tating at the shoulder-joint, iii. 713. Onychia, maligna. See Ingrowing of the Nails. Oppenheim on the introduction of the seton in false joints, ii. 20; case of excision of the head of the femur, iii. 737. Orchitis. See Inflammation of the Testicle. Organic parts lost, restoration of:— history of nose-making, iii. 577; the Indian method, iii. 375; the Talacotian operation, iii. 577; practised in England by Lynn, Sutcliffe, and Carpue, iii. 577; Graefe's modification of the Taliacotian operation, iii, 577; the second Indian method, iii. 578; South on the practice df plastic surgery in England, iii. 578 ; the several methods of reparation by a fold of skin from the neighbourhood, iii. 579; the value of plastic operations, iii. 579; rhinoplasty, and its occasional unfavour- able results, iii, 580; subsequent changes in the new nose, iii. 580; the Indian ope- ration preferable, iii. 580; Balfour, Braid, South, Barthelemy, and Regnault's cases of reunion of separated parts, iii, 581; nose-making from the skin of the forehead, iii. 582; the Indian method of rhinoplasty, iii. 582; directions for the operation, iii. 583; Graefe, Dieffenbach, Delpech, and Labat'smodificationsuii. 584; subsequent symptoms and treatment, iii. 585; occur- rence of gangrene, iii. 585; removal of the stitches or pins, iii. 585; division of the fold of skin after complete union of the new nose, iii. 585; after-operations for perfecting the form of the nose, iii. 586 ; Graefe on. the proper formation of the nostrils, iii. 586; defects of the wings of the nose, iii. 586 ; Dieffenbach's opera- tion, iii. 587; deficiency of the side-edge as well as of the wing of the nose, iii. 587; the bridge of the nose sunken in, iii, 587; directions for the operation, iii. 587 ; Dieffenbach's modification of the opera- tion, iii. 587; deficient columna narium, iii. 587 ; the operation, iii. 587 ; bottle- nose, and the operation to remedy the de- formity, iii. 587; Gensoul's modification of the operation for deficient colurnna narium, iii. 588; Gensoul's case of chilo- plasty, to remedy the deformity caused by gangrene, iii. 588; forming the nose from the skin of the arm, iii. 588 ; a more troublesome and uncertain operation than the Indian method, iii. 589; directions for the German operation, iii. 589; Benedict and Galenzowski's modifications of the operation, iii. 589 ; the Italian operation, as modified by Graefe, iii. 590; raising a sunken nose, iii. 590; Dieffenbach's opera- tion, iii. 590; dressing and after-treat- ment, iii. 591; Liston and Fergusson's operations, iii. 591; Dieffenbach's opera- tion for dropping in of the bridge of the nose, from destruction of part of the sep- tum, iii. 592; the inhealing of metallic frames to remedy sunken noses, iii. 592; Tyrrell's case, iii. 592; Dieffenbach's operation to remedy the turning down- wards of the tip of the nose, iii. 592; me- chanical compensation for lost parts, iii. 593 ; artificial legs, iii. 593 ; the wooden leg, iii. 593; Pare, Ravaton, White, Addi- son, Wilson, Briinninghausen,Stark, Ber- rens, Heine, Graefe, Ruhl, Palm, Dorn- bluth, Schmucker, Wals, Miles, and Serre's artificial legs, iii. 593 ; selection of an artificial leg, iii. 593; description of Ruhl's artificial leg, iii. 594; of Stark's artificial thigh, iii. 594; description and application of the wooden leg, iii. 594; Ruhl's wooden leg, iii. 594; artificial foot, iii. 595 ; artificial hands, iii. 595; Pliny, Gotz von Berlichingen, Pare, Wilson,and Ballifs artificial hands, iii. 595; artificial upper arms, iii. 595 ; description of the apparatus, iii. 596 ; artificial noses and ears, iii. 596; supply of lost portions of the hard palate, iii. 596; use of obturators, iii. 596 ; replacement of the teeth, iii. 596; transplantation of teeth, iii. 596; applica- tion of artificial teeth, iii. 596. —— superfluity of : — supernumerary fingers and toes, iii. 597 ; two different forms, iii. 597; treatment by operationjii. 597; supernumerary teeth, iii. 597; causes, iii. 597; deformity caused by the irregular position of the teeth, iii. 597; treatment, iii. 597; double nose, iii. 598; either con- genital or acquired, iii. 598; enormous degeneration of the nose, and its treat- ment by operation, iii. 598; treatment of cleft nose, iii. 598; Hey's case of immense tumour of the nose, iii. 598 ; Dalrymple on the nature and characters of these tu- mours, iii. 598. Oribasius on the removal of the relaxed uvula by cutting, i. 166, Orioli's case of fungus of the dura mater, treated by operation, iii 425. Orred's case of excision of a joint, iii. 726; mode of operating in excision of the head of the humerus, iii. 732. Osborne, Dr., on the application of leeches to mucous surfaces, iii. 613; use of the polytome, iii. 616. Os calcis, fracture of, i. 639 ; dislocation of, i. 251. Os hyoides, fracture of, i. 581. Osiander on the operation for the treat- ment of lacerated perineum, ii. 39; on 894 ANALYTICAL INDEX. the extirpation of the cancerous neck of the womb, iii. 566. O'Shaughnessy's case of removal of the upper-jaw, iii. 759, Osteosarcoma, iii. 412. Osteosteatoma, iii. 412. Otto on hydrocephalocele, ii. 363; on the causes of cerebral rupture, ii. 364. Outrepont on the causes of congenital dislocation, ii. 208. Ovarian dropsy, iii. 209. Ovaritis regarded by Ricord a complication of gonorrhoea, i. 180. Ovary, extirpation of, iii. 209. Owen's case of viper-bite, i. 392; on the post-mortem appearances in Stevens' case of ligature of the internal iliac, ii. 534. Paget's case of diseased undescended tes- ticle, iii. 558. Paillaud on iodine in hard swellings of the testicle, ii. 101. Pailloux on the cause of the difficulty ex- perienced in reducing dislocations of the thumb from the metacarpal bone, ii. 235. Pajola's mode of operating for stone, iii. 324. Palate, hard, cleft in the, ii. 27. ----, soft, cleft in the, ii. 30. Palletta on congenital dislocation of the hip, ii. 207, 244 ; on the post-mortem ap- pearances in, ii, 244; case of congenital dislocation of the patella, ii. 247; of ex- tirpation of the womb, ii. 570. Palmer on the torsion of arteries, i. 341. Paracentesis thoracis, iii. 194 ; abdominis, iii. 204; uteri, iii. 218; of the intestines in tympanitis, iii. 218. Paraphimosis, iii. 60. Pare Ambrose, used the ligature in cases of relaxed uvula, i. 166 ; on the operation for the treatment of ingrowing of the nail, i. 224; on the use of the ligature for wounded vessels, i. 354; bandage for fractured clavicle, i, 603; on the rotation of the foot outwards in fracture of the neck of the femur, i. 618; apparatus for fracture of the neck of the femur, i. 623; on the operation for lacerated perineum, ii. 39; on congenital dislocation of the hip, ii. 207; on ligature of the hernial sac for its radical cure, ii. 283; on the operation of dilating the abdominal ring, the hernial sac being unopened, ii. 303; on the causes of club-foot, ii. 446. Parent on the hydrarg. cyan, in syphilis, ii. 93. Paris', Dr., case of a foreign body remain- ing a long while in the windpipe, iii. 112; on cancer of the scrotum, iii. 560. Park's case of excision of a joint, iii. 726 : mode of operating in excision of the knee-joint, iii. 740; on the mode of union after the operation, iii. 741. Paronychia, i. 215. Parotid duct, fistula of, ii. 149. Parotid gland, inflammation of, i. 167; abscess of, i. 168; cancer of, ii. 522; diseases of, iii. 522; extirpation of, iii. 522. Patella, fracture of, i. 630; dislocation of, ii. 246. Pattison's case of teleangiectasy treated by acupuncture with red-hot needles, ii. 565. Pauli on tattooing moles of the skin, ii. 566. PaUlus jEgineta on the removal of the relaxed uvula by cutting, i. 166; cau- terized it with the aid of the staphylo- kauston, i. 166; on the application of the actual cautery for the radical cure of her- nia, ii. 282; on aneurism, iii. 468. Pearson's, Dr., opinion relative to the formation of pus, i. 46. Pearson opposed to incisions in carbuncle, i. 157; on the symptoms preceding and accompanying the formation of a lumbar abscess, i. 208; on the situation of the external abscess, i. 210; prefers making a small aperture in lumbar abscess, and treating the ulcer in a gentle manner, i. 213 ; on the treatment of the sinuous cavities resulting from lumbar abscess, by injections, i. 214; states that the larger arteries sometimes ulcerate into the ab- scess, i. 214 ; on venereal paronychia, i. 217; on erethismus mercurialis, ii. 109; on the cachexia syphiloidea, ii. 110; on the eczema mercuriale, ii. Ill; on the treatment of erethismus mercurialis and eczema mercuriale, ii. 113 Pelletan on the mechanism of the fat rupture when it descends through the inguinal canal, ii. 325 ; case of the exist- ence of several aneurisms in the same person, ii. 477. Pellieux on the symptoms of dislocation of the sternal end of the clavicle back- wards, ii. 217. Pelouze's experiments on stone-solvents, iii. 281. Pelvic bones, fracture of, i. 595; disloca- tion of, ii. 214. Penada's case of hydrocephalocele, ii. 363; Penis, cancer of, iii. 543; amputation of, iii. 544 ; by ligature, iii. 546. Penis, wounds of, i. 534; treatment of these wounds, i. 534; laceration of the cavernous bodies by forcibly binding the penis during erection, i. 534; conse- quences and treatment, i. 534; South on ANALYTICAL INDEX. 895 incising the spongy body of the penis not always a cause of loss of the power of erection, i. 535; Moller's case of gan- grene of the penis from the constriction of a metal ring, i. 535; South's objection to amputation of the penis for lacerations of the cavernous bodies, i. 535; rupture of the urethra, i. 535; symptoms and treatment, i. 535; South on the treatment of rupture of the urethra, i. 535. Pennock, Dr., on the effects of cupping glasses in vipers' bites, i. 389. Pentzlin on the treatment of itch, ii. 68. Percival, Dr., on an epidemic vaginal ca- tarrh, i. 181. Percy on the removal of foreign bodies in injuries of the brain, i. 438 ; on the solu- tion of the chloride of lime in the treat- ment of foul, gangrenous, or torpid ulcers, ii. 44; on passing a leaden thread into Steno's duct, after the cheek has been penetrated, in the operation for salivary fistula, ii. 148; operation for enlargement of the tongue, iii. 384 ; moxa made with the pith of the sun-flower, iii. 631; on the excision of joints, iii. 726. Pericardium, wounds of, i. 501. See Wounds of the Chest. Perineal fistula, ii. 181; abscess, ii. 181; rupture, ii. 355. Perineum, female, lacerations of, ii. 35; causes, situation, and extent, i. 36; slight lacerations, ii. 36; results of extensive lacerations, ii. 36; inability to retain the faeces in complete laceration from the vagina to the rectum, ii. 36; treatment of extensive laceration, ii. 36; by sutures, ii. 36; by position, ii. 36; central lace- ration, ii. 36; treatment of large and recent lacerations by the stitch, ii. 36; Duparcque on the treatment of lacerations of the perineum, ii. 36; results of these lacerations, ii, 37 ; Dr. Churchill on the treatment of lacerated perineum, ii. 37 ; Duparcque on the scarring of the edges of the torn perineum, ii. 37; operations on old lacerations when extending into the rectum uncertain in their consequen- ces, ii. 38; when contra-indicated, ii. 38; description of the operation, ii, 38; Am- brose Pare, Guillebonneau, Mauriceau, La Motte, Smellie, Noel, Saucerotte, Du puytren, Mursinna, Menzel, Osiander, Dieffenbach, Montain, and Roux on this operation, ii. 39; Guillebonneau, Mau- riceau, La Motte, Smellie, Noel, Sauce- rotte, Dieffenbach, Roux, Montain, and Ritgeon on the application of sutures, n. 39; Davidson's successful operation, n. 39; subsequent treatment, it. 40; Dief- fenbach on the artificial retention of faeces for several days after the operation, n 40; Saucerotte, Roux, and Davidson's cases, ii. 40 ; Horner's recommendation to divide the sphincter ani, after union has taken place, ii. 40; mode of union of old lacerations, ii. 40; Nevermann's treatment by cauterizing with unslaked lime, and afterwards by position, ii. 40. Peroneal artery, ligature of, ii. 544. Perrault's case 6f amputation at the hip- joint, iii. 689. Perrez on the physiology of carbuncle, i. 155; on the treatment of carbuncle, i. 158. Perry's case of aneurism bursting into a vein, ii. 551; case of necrosis of the lower jaw, iii, 753. Petit's explanation of the lengthening of the limb in hip-disease, i. 285; on the reduction of the consecutive dislocation, i. 297; on the arrest of haemorrhage by nature, i. 329 ; on the healing of wounds of aTteries, i. 330; on the more general application of the trephine, i. 454; ban- dage and slippers for rupture of the tendo Achillis, i. 542; bandage for fractured clavicle, i. 603; on the rotation of the foot outwards in fracture of the neck of the femur, i. 618; on incision of the hernial sac, etc., for its radical cure, ii. 283; case of impending peritonitis from ligature of the hernial sac, ii. 288; on the operation of dilating the abdominal ring, the hernial sac being unopened, ii. 303; on the coagula in varicose veins, ii. 568; case of varices in the upper extremity, ii. 570 ; cases in which severe symptoms followed the application of the ligature for piles, ii. 584 ; mode of amputating by the circular incision, iii. 640. Peyronie's M. La, case of abscess of the dura mater, i. 439. Phagedena, sloughing. See Mortification, Philip's, Dr. Wilson, experiments on the condition of the vessels in inflammation, i. 40; on the treatment of uric acid gravel, iii. 260. Phillips' case of fracture of the first ver- tebra, and pivot process of the second, i. 584 ; post-mortem appearances^ i. 585; case of prolapsed womb treated by cau- terization of the vaginal parietes, ii. 378; on the application of the actual cautery in treating prolapse, ii, 402; on acupunc- ture in aneurism, ii. 503 ; case of a stick in the rectum, iii. 108; on the statistics of the operations for the extirpation of the ovary, iii. 213; on the results of ampu- tation, iii. 656. Phimosis, iii. 53. Phlebitis, i. 92; causes, symptoms, and terminations, i.92; Cruveilhierand South on phlebitis, i. 92; Hunter on thecoagu- 896 ANALYTICAL INDEX. lation of the blood in phlebitis, i. 93 ; Hunter, Abernethy, Hodgson, Carmi- chael, Bouillaud, Travers, and Arnott on severe phlebitis, i. 93; Ribes' cases of phlebitis, i. 94; Arnott on the morbid appearances in phlebitis, i. 95; Dr. Robert Lee on inflammation of the femo- ral and iliac veins, an occasional cause of phlegmasia dolens, i. 95 ; Abernethy on the treatment of traumatic phlebitis, iii. 610. Phlebotomy, iii. 608. Phlegmasia dolens, Dr. R. Lee on inflam- mation of the femoral and iliac veins, an occasional cause of, i. 95, Phrenic rupture, ii. 356. Physick, Dr., on the treatment of carbuncle, i. 157; guillotine instrument for ampu- tating the tonsils, i. 165; on the treat- ment of coxalgia, i. 292; on the animal ligature, i. 339; apparatus for fracture of the neck of the femur, i. 623; on the use of the seton in false joints, ii. 20; opera- tion for artificial anus, ii. 158; on the mode of performing the Caesarian opera- tion, iii. 163. Piedagnel on the cause of death from the entrance of air into a vein, iii. 603. Pigne on the changes which the substance of bone undergoes in advanced age, i. 545; on sawing off the ends of the broken bone in false joints, ii. 18; on the direc- tion and position of natural and acquired hare-lip, ii. 22 ; on the solution of the chloride of lime in the treatment of foul, gangrenous, or torpid ulcers, ii. 44; on the treatment of syphilitic phimosis, iii. 59 ; on hydrocele caused by gonorrhea, iii. 224; on the nature of corns, iii. 402; on the seat of exostosis, iii. 408. Pilore's case in which he made an artificial anus on the right side by opening the caecum, iii. 38. Pinel's opinions relative to the formation of pus, i. 47. Piorry on the physical characters of dropsy of the pericardium, iii. 201. Pitcairn, Dr., on immediate amputation in gun-shot wounds, i. 383; on gold and its preparations in primary and secondary syphilis, ii. 101. Pitschaft's cases of suppurating protru- sion of the brain in children, ii. 367. Planchon's case of fatal punctured wound of the womb, i. 533. Plantade's mode of amputating at the hip-joint with the flap-cut with a single flap, iii. 691. Plattner's artery-compressor, i. 331. Plenck on the lengthening of the limb in hip-disease, i. 285. Ploucquet's case of foreign body in the heart, i. 500. Pockels on the formation of new vessels, i. 323. Poisoned Wounds. See Wounds. Poller on puncturing the|bladder, iii. 155. Polypus, iii. 468 ; of the nostrils, iii. 468; of the throat, iii. 478; of the oesophagus, iii: 478 ; in the maxillary sinus, iii. 479 ; of the womb, iii. 486 ; of the vagina, iii. 494; of the rectum, iii. 494. Popliteal artery, ligature of, ii. 542. Portal's case of inflammation of the aorta, consequent on the recession of measles, i. 89; on the ossification of arteries in young children, i. 91; case of fatal hemorrhage consecutive to the opening a tonsillar abscess, i. 161; on the lengthen- ing of the limb in hip-disease, i. 285; mode of amputating by the circular in- cision, iii. 641. Portalupi's case of very large fatty tu- mour, iii. 427. Porte, De la, on the extirpation of the ovary, iii. 210. Porter's case of wound of the popliteal artery by a sequestrum, ii. 130; on the passage of foreign bodies into the larynx, iii. 110. Posch's apparatus for fractures of the leg, i. 637. Posselt's chemical analysis of the fluid contained in ranula, iii. 122. Post's, Dr., case of ligature of the subcla- vian above the clavicle, ii. 518, 519; on the ligature of the external iliac, ii. 538. Pott on the diseased condition of the spine in lumbar abscess, i. 208 ; on the symp- toms and progress of inflammation in the joints of the vertebrae, i. 308; on the so- called palsy of the limbs in Pott's disease, i. 309 ; on the puffy, circumscribed, in- dolent tumour of the scalp, indicative of suppuration between the dura mater and the skull, i. 424; on the symptoms accom- panying fracture of the skull, not depend- ing on the injury to the bone, but from injury to the brain, or of some of the parts contained in the cranium, i. 429; on puncturing the dura mater, when the ex- travasation lies beneath, i. 447; on extra- vasation between the meninges, or on the surface of the brain, i. 447; on the more general application of the trephine, i. 454; on the bent position in fracture of the femur, i. 628; on effusion of blood into cellular tissue of the scrotum, iii.175; on hematocele of the spermatic cord, iii. 178 ; case of fusible calculus in a vesical rupture, iii. 273 ; on cancer of the scro- tum, iii. 560; on the age at which chimney-sweep's cancer generally occurs, ANALYTICAL INDEX. 897 iii. 560; mode of operating in amputa- tion, iii. 642. PoTTER,on the results of amputation,iii.655. Pouteau recommends emetics in hospital gangrene, i. 114; on the application of caustic and the actual cautery in car- buncle, i. 158; on the arrest of haemor- rhage by nature, i. 329; objection to dressing the wound, after the operation for rectal fistula, ii. 167. Powell's, Dr., case of a hydrophobic patient biting another person, i. 406. Powell's case of rupture of the womb not fatal, i. 531. Pravaz on the reduction of congenital dis- location of the femur, ii. 243; case of suc- cessful reduction, ii. 244; on acupuncture of the aneurismal sac, and the application of galvanism, ii. 503. Preiss on the exhibition of purgatives in strangulated hernia, ii. 291; on the opera- tion of dilating the abdominal ring, the hernial sac being unopened, ii. 303. Pring's case of operation for artificial anus at the lower end of the colon, iii. 38. Prochaska's case of sympathetic abscess i of the brain, with irritation and suppura- tion of the dura mater, i. 442. Prolapses :—definition, ii. 368; causes, ii. 368; prolapse of the womb, ii. 368; varie- ties and complications, ii. 369 ; Sabatier and Blundell on prolapse of, ii. 369; symptoms of incomplete prolapse, ii. 369; Blundell on relaxation and incomplete prolapse, ii. 370; Ramsbotham on the ob- struction to the passage of the urine in prolapse of, ii. 370; South on the irrita- tion of the rectum in prolapse of, ii. 370; complete prolapse, symptoms and results, ii. 370; Blundell on the size of the pro- lapsed womb and vagina, ii. 371; Cru- veilhier and South on the contents of the sac formed by the prolapsed vagina, ii. 371; Clarke on the length of time during which the prolapse is forming, ii. 371; Cruveilhier on incontinence of urine in prolapse of the womb, ii 372; Clarke on the size and shape of the prolapsed organ, ii. 372; Cruveilhier on the altered form and direction of the os uteri in prolapse of that organ, ii. 372; Cruveilhier and Cloquet on the elongation of the womb in cases of prolapse, ii. 372; Ramsbotham on the general symptoms of prolapse and procidentia, ii. 372; Clarke on the con- secutive ulceration of the vagina,ii, 372; Cloquet and Cruveilhier on the existence of calculi in the displaced bladder conse- quent on prolapsus uteri, ii. 372; Cru- veilhier and Cloquet on consecutive dis- placement of the rectum, iL 372; causes of prolapsus uteri, ii. 372; Blundell and I Vol. hi.—76 Ramsbotham on the causes of prolapse, ii. 372; Elliotson, S. Cooper, and Rams- botham's cases of prolapse of the womb in virgins, ii. 373; Ullsamer on endemic prolapse of the womb from the use of the labour-chair, ii. 375; Clarke's case of pro- cidentia uteri, with separation of the bones of the pelvis, ii. 374; prognosis, ii. 374; treatment, ii. 374; mode of reducing the prolapse, ii. 374; Ruysch and Sabatier on the reduction of the prolapsed and ulcerated womb, ii. 375; Sabatier on the treatment of the prolapsed pregnant womb, ii. 375; after-treatment, ii. °375 ; Clarke on the after-treatment of proci- dentia uteri, ii. 375; Clarke on the appli- cation of injections, ii. 376; Clarke on the treatment of the ulcerated vagina, ii. 376; Clarke's objections to sponge as a pessary, ii. 376; use of pessaries, ii. 376; the oval pessary and its application, ii. 376; Clarke's pessary, ii. 377; inconvenience of pessaries, ii. 377; Hull's utero-abdo- minal supporter, ii. 377; King's bandage, ii. 378; Phillips' case of prolapse treated by cauterization of the parietes of the va- gina, ii. 378; Clarke on the corrosion of pessaries in the passage, and on the de- posit of calculous matter on them,ii. 378; Hall, Ireland, Velpeau, and Berard's operation for prolapse, ii. 379; Dieffen- bach and Lawrieon the use of the actual cautery in prolapse, ii. 379 ; Ker's case of procidentia treated with the secale cor- nutum, ii. 379; Bellini's operation, ii. 380; Fricke's operation of episioraphy, ii. 380; Gedding's cases in which episio- raphy was performed, ii. 380; symptoms sometimes following the reduction of an old prolapse, ii. 380; removal of the pro- lapsed organ when scirrhous, by the ligature or by incision, ii. 380; introduc- tion of the catheter in cases of prolapse, ii. 380; Recamier, Marjolin, Cruveilhier, and Langenbeck on excision of the pro- lapsed scirrhous womb, ii. 381 ; prolapse of the womb with inversion, ii. 382; defi- nition, ii. 382; varieties, ii. 382; Crosse on the characters of the respective va- rieties, ii. 382; Crosse on the successive steps of the inverting process, ii. 383 ; Crosse on the concavity formed in all cases of inversion, ii. 383 ; causes, ii. 384; Hachmann on spontaneous inver- sion from spasm, ii. 3S4; Clarke and Crosse on polypus of the fundus uteri as a cause of inversion, ii. 384; Crosse on coagulated blood, hydatids and moles in the womb as causes of inversion, ii. 384; symptoms of the quickly-formed inver- sion, ii. 384; Dailliez on strangulation of intestine in the concavity formed by the ^98 ANALYTICAL INDEX. inverted womb, ii. 385; Clarke on the character of the discharge in inverted uterus, ii. 385; diagnosis of inversion from prolapse, ii. 386 ; reduction of the inverted womb, ii. 386; after-treatment, ii. 386; treatment when the reduction cannot be effected, ii. 386; when the pla- centa is attached to the inverted organ, ii. 387; in chronic inversion, ii. 387; Clarke on the treatment of chronic inver- sion, ii. 387 ; Clarke on the treatment of recent inversion, ii. 387 ; Clarke on the diagnosis between chronic inversion and polypus uteri, ii. 387; treatment when the reduction of the inverted organ is impossible, ii. 387; removal of the in- verted womb, if affected with cancer or other degeneration, ii. 387; Clarke on the treatment of the inverted womb, compli- cated with procidentia, ii. 388 ; Clarke, Chevalier, Blundell, Dr. J. Clarke, and Dr. Symonds' cases of removal of the inverted womb by ligature, ii. 388; pro- lapse of the vagina, ii. 389; definition and varieties, ii. 389 ; Clarke and John Burns on prolapse of the vagina, ii. 389; charac- ters of complete prolapse, ii. 389; of im- perfect prolapse, ii. 389; diagnosis be- tween prolapse of the vagina and of the womb, ii. 389; Clarke and Blundell on the symptoms of prolapse of the vagina, ii. 390; predisposing and occasional causes, ii. 390; Clarke on the causes and symptoms of posterior prolapse of the vagina, ii. 390; reduction of the prolapse, ii. 390 ; Clarke on the treatment of pos- terior prolapse, ii. 390 ; after-treatment, ii. 390; prolapse of the bladder, ii. 391 ; symptoms, ii. 391; diagnosis between prolapse of the bladder and of the womb, ii. 392 ; treatment, ii. 392 ; South's case of prolapse of the bladder relieved by operation, ii. 393 ; Lightfoot's case in which he performed the operation of episioraphy, ii. 396 ; prolapse of the rec turn, ii. 397 ; three forms of prolapse of the rectum, ii. 397; Copeland on pro- lapse of the internal membrane of the rectum, ii. 398; Syme on prolapsus ani, ii. 398; Bushe describes two forms of prolapsed rectum, ii. 398 ; Berard jun.'s case of invagination of the rectum through the anus, ii. 398 ; characters of prolapse of the internal coat of the rec- tum, ii. 398 ; of prolapse of all the coats, ii. 399; symptoms, ii. 399; Bushe on the characters of prolapse, ii. 399; Syme on the characters of prolapsus ani, ii. 399 ; Copeland, Syme, and Bushe on the diag- nosis between prolapsed rectum and haemorrhoids, and intus-susception, ii. 399; causes, ii. 399; Bushe on the changes in the mucous membrane of the rectum in old prolapses, ii. 399; treat- ment, ii. 400 ; reduction of the prolapse, ii. 400; Brodie and South on the treat- ment of prolapse in children, ii 401; Dupuytren objects to scarifications or leeches in treating prolapse of the rectum, ii. 401; prevention of the return of the prolapse, ii. 401; Klein and Schwartz on the treatment of prolapse, ii. 401; Brodie on the treatment of prolapsed rectum with piles in the adult, ii. 401 ; Dupuy- tren's operation for long-standing pro- lapse, ii. 402; Phillips on the application of the actual cautery in treating prolapse, ii. 402; Hey on the cause of the difficulty in reducing the bowel in old prolapses, ii. 402; Hey's operation, ii. 402; Vel- peau's modification, ii. 403 ; Copeland's operation, ii. 403; McCormac on careful traction of the skin in prolapse of the rec- tum, ii. 404; changes that take place in old prolapses, ii. 404; extirpation of the degenerated parts, ii. 404; Salmon's ope- ration, ii. 404 ; application of the actual cautery in irreducible prolapse, ii. 404; Ansiaux and Dupuytren on the actual cautery in irreducible prolapse, ii. 404; prolapse of an ensheathed upper intestine, ii. 405 ; Bushe on relaxation of the anus, ii. 405; causes, signs, and results, ii. 405; Bushe on relaxation of the rectum with invagination of the mucous mem- brane, ii. 405; causes, symptoms, and treatment, ii. 405; Somme's case, ii. 405; Salmon on the incautious use of enemata a cause of relaxed rectum, ii. 406. Prostate, retention of urine from inflamma- tion of, iii. 136; suppuration and abscess of, iii. 136; swelling of, from varicose veins, iii, 138; induration of, iii. 138; chronic, enlargement of, iii. 139; reten- tion of urine from, iii. 141; stones in the, iii. 366. Prout, Dr., on the origin of oxalic acid in the urine, iii. 244; on lithic or uric acid sediments, iii. 253; characters of yellow sediments, iii. 253 ; of red or lateritious sediments, iii. 253 ; of pink sediments, iii. 253; white lithate or urate of soda sediment, iii. 254; characters and accom- panying symptoms of the phosphatic sediments, iii 254 ; causes, iii. 255; oxa- late of lime sediment, iii. 256; charac- ters of the urine in cystic oxide calculus, iii. 256; characters and symptoms of crystallized uric acid gravel, iii. 256; on the crystallized phosphatic gravel, iii. 256; on the rarity of crystallized oxalate of lime gravel, iii. 257; on the treatment of a fit of the gravel, iii. 260; of cystic oxide gravel, iii. 262; of the oxalate of ANALYTICAL INDEX. 899 lime diathesis, iii. 262; of the phosphatic diathesis, iii. 263; on the formation of uric acid calculi in the kidneys, iii. 265; on renal calculi of oxalate of lime, iii. 265; on renal calculi of cystic oxide, iii. 266; on the rarity of phosphatic renal calculi, iii.267; on the treatment of nephri- tis complicating renal calculi, iii. 268; on the spontaneous breaking up of calculi in the bladder, iii. 275; on the symptoms of vesical calculus, iii. 275; on the use of stone solvents, iii. 281. Psoitis. See Inflammation of the Lumbar Muscles. Psoas abscess, i. 208. Psora, ii. 63. Pudic, common, ligature of, ii. 575. Punctured wounds, i. 366. See Wounds. Pus, the secretion of, i. 46 ; resorption of, i. 48 ; Vogel and Bonnet on the effects of, i. 48 ; qualities of pure good pus, i. 50; formation of, i. 51 ; Travers on the pur- poses which the formation of pus serves' in the economy, i. 51 ; Hunter on the qualities of pus and the pus globules, i. 51; Hunter and Gulliver on the putre- faction of pus, i. 51 ; Senac on the globu- lar structures of, i. 51 ; Gueterbock on the composition and chemical analysis, of, i. 52; composition of the serum of, i. 52 ; fatty vesicles discovered by Henle in the serum of, i. 52; Gueterbock's discovery of pyine, i. 52;charactersofpus globules, i. 52 ; Mandt on the pus globules, i. 52; discovery of the difference in size of the pus globules by Gueterbock, i. 53 ; Mayo describes the occasional occurrence of pus globules in healthy blood, i 53 ; denied by Gulliver, i. 53; Gerber's account of the formation of pus, and of the re- productive organization in suppurating wounds, i. 53 ; Travers on the constitu- tion of pus, i. 54 ; varieties of, i. 55 ; dis- tinguishing characters of laudable pus, and ichor or sanies, i. 55; the presence of globules in the serum proved by Bayer, Faraday, and Mandt, i. 55 ; characters of the albumen in pus, i. 56; Grassmeyer and Fischer on the distinguishing tests for pus and mucus, i. 56 ; Gruithuisen's microscopic tests for pus and mucus, i. 56; Gerber's description of ichor, puri- form mucus, and serous exudation, i 56 ; pus cannot be produced without inflam- mation, i. 57 ; diathesis purulenta, i. 57. Pustule, malignant. See Mortification. Puthod's mode of amputating at the hip- joint with the flap-cut with a single flap, iii. 691. Quassoud on mortification from spurred rye, i. 74. Quesnay's opinion relative to the formation of pus, i. 46; on the more general appli- cation of the trephine, i. 453; on the stanching the bleeding in wound of the intercostal artery, i. 492. Quinsy. See Inflammation of the Tonsils. Radial artery, ligature, of, ii. 530. Radius, fracture of, i. 610 ; dislocation of, ii. 232. Rainey on a peculiar degeneration of the cartilage in disease of the knee, i. 302. Ramel's case of displacement of the heart, ii. 361. Ramsbotham, Dr., on the obstruction to the passage of the urine in prolapse of the womb, ii. 370; on the general symptoms of prolapse and procidentia, ii. 372; of the causes of the prolapse, ii. 372 ; cases of prolapse in a virgin, ii. 373. Ramsden's case of lumbar abscess, i. 210 ; of fatal contraction and ulceration of the intestine, after strangulation, ii. 310 ; of ligature of the subclavian above the cla- vicle, ii. 519. Ranby on immediate amputation in gun- shot wounds, i. 380. Ranula, iii. 120. Rau's mode of operating for stone, ii. 307. Ravaton's slippers for rupture of the tendo Achillis, i. 542. Ravin on increased pressure and the supine posture in the radical cure for hernia, ii. 282. Rayer on erysipelas, i. 116 ; opinion that carbuncle occurs most frequently inspring and summer, i. 156; on incisions in car- buncle, i. 157. Raynaud's operation for varicocele, ii. 578. Recamier on the excision of the prolapsed and scirrhous womb, ii. 381 ; fatal opera- tion for ovarian dropsy, iii. 210 ; on com- pression in scirrhus, iii. 511; operation when the neck of the womb is softened or destroyed, iii. 567; cases of removal of the womb by ligature, iii. 569 ; on ex- tirpation of the womb, iii. 572. Rectal fistula, ii. 161. -----rupture,, ii. 356. Recto-urethral fistula, ii. 185. -----vaginal-----, ii. 198. -----vesical-----, ii. 185. Rectum, prolapse of, ii. 397; stricture of, iii. 34; foreign bodies in the, iii. 108; polypus of, iii. 495. Regal de Gaillac on extirpation of bron- chocele by subcutaneous ligature, iii. 399. Regnault's case of re-union of divided parts, iii. 582. Regnoli's operation for the extirpation of the tongue, iii. 521. Reinhardt on the mode of reducing dis-lo- 900 ANALYTICAL INDEX. cations of the thumb from the metacarpal bone, ii. 235. Reisinger's apparatus for ligaturing com- plete rectal fistulae, ii. 169 ; mode of ap- plying the apparatus, ii. 169. Renal calculi, iii. 264. Renaud's apparatus for simultaneous frac- ture of both clavicles, i. 604. Rennerth on the exhibition of purgatives, &,cl, in strangulated hernia, ii. 291. Renucci on the existence of the acarus scabiei, ii. 67. Reybard's canula useless in wounds of the intercostal artery, i. 491 ; plan for stanch- ing bleeding from the intercostal artery, i. 491; mode of practice in wounded in- testine, i. 510; modification of Dupuy- tren's operation for artificial anus, ii. 153. Reynaud on the treatment of buboes, ii. 90. Resolution, a result of inflammation, i. 42; signs of resolution, i. 42; distinguished , from the recession of inflammation, i. 42 ; Dr. J. H. Bennett on the process of ] resolution, i. 43 ; Schonlein and Zimmer- mann on the elimination of the molecu- lar fibrin, i. 43; resolution, an ordinary termination of orchitis, i. 202. Rheumatism, gonorrheal, i. 342. Rhinoplasty, iii. 580. Riadore's case of excision of the part of the hand, ii. 722. Ribes' case of phlebitis, i. 96; on the in-. ternal opening of rectal fistula, ii. 102; on the application of the taxis in strangu- lated hernia, ii. 291. Ribieri on local anodyne applications in strangulated hernia, ii. 291. Ribs, fracture of, i. 599 ; dislocation of, and of their cartilages, ii. 215; resection of, iii. 765. • Richerand on the treatment of ingrowing of the nail, i. 222; of fractured clavicle, . L 603 ; of fracture of the neck of the hu- merus, i. 607; of the neck of the femur, i. 624; on the primitive direction of dis- location of the humerus, ii. 222; on puncturing the distended intestine, after the operation for strangulated hernia, ii. 299; on the occurrence of aneurism in dissecting-room servants, ii. 474; on the application of pounded ice to aneurisms, ii. 480; on compression in the treatment of aneurism, ii, 483 ; on the respective origins of benignant and malignant nasal polypi, iii, 470; objections to the upper flap in partial amputation of the foot, iii. 705. Richon on the treatment of gonorrhea, i. 198. Richter on the extirpation of the tonsils by cutting, i, 164; on dry whitlow, i, 218; on the lengthening of the limb in hip-disease, i. 285; on the resection of the carious head of the femur in hip-disease, i. 299; only employs trepanning in inju- ries of the head when secondary symp- toms of irritation and pressure require it, i. 454 ; gutter-shaped piece of card-board useless in wounds of an intercostal artery, i. 491 ; bandage for fractured clavicle, i. 604 ; On the treatment of Salivary fistula, ii. 147; objections to the useof the cathe- ter in urethral fistula, ii. 182; on the re- duction en masse, ii. 274; on increased pressure and the supine posture for the radical cure of hernia, ii. 282; on the radical cure by incision and scarifications of the sac, ii. 283 ; on dilatation of the stricture in strangulated hernia, without eutting, ii. 298; case of yielding of the abdominal parietes, ii. 349; cauterizes ranula in children with lunar caustic, iii. , 123 ; mode of amputating by the circular incision, iii. 639. Ricord on acute urethritis in the female, i. 180; on utero-vaginal gonorrhea, i. 180; regards ovaritis as a complication of gonorrhea, i. 180; on abscesses compli- cating gonorrhea, i. 180; experiments on the identity of gonorrhea and syphilis, i. 183, 186; inferences from the results of the inoculation of gonorrheal matter, i. 186; opinion that gonorrhea is unattended by ulceration controverted, i. 186; on the examination of public prostitutes, i. 189; treatment of gonorrhea by the direct ap- plication of nitrate of silver, i. 191; on the remedies for chordee, i. 192; on the arrest of haemorrhage from the urethra, i. 192; on the treatment of gonorrhea in women, i. 193; treatment of severe cases by the introduction of a plug of lint dipped in some emollient narcotic liquid, i. 193; treatment of obstinate cases by filling the vagina with dry lint, i. 193; ulcerations and papulous granulations to be cauterized, i. 193; on ulcerations of the mucous membrane of the womb, i. 193; vegetations in the interior of the urethra to be destroyed by incision or cauterization, i. 193; on gonorrhea in the female urethra, i. 194; on inoculation with gonorrheal matter to cure gleet, i. 195; on the treatment of balanitis, i. 199; on syphilitic swelling of the testicle, i. 200; describes it as syphilitic sarcocele, i. 200; on the period at which chancres appear after infection, ii. 71; on inocula- tion for the purpose of distinguishing syphilitic sores, whether primary or se- condary, ii. 74; on the seven kinds of buboes, ii. 75; on the existence of sy- philitic buboes without primary sore, ii. ANALYTICAL INDEX. ©01 77; on the non-infectious character of the pus from a secondary syphilitic sore, u. 79; on the causes of the varied appear- ances of chancre or primary syphilitic sore, ii. 83>; en the destruction of the ulcer by the nitrate of silver, ii. 86 ; on the treatment of buboes, ii. 89 ; on iodine in gonorrhea and bubo, ii. 101; on the possibility of infection from' secondary syphilis, ii. 106; on urethroplasty, ii. 179; on the application of the ligature in the treatment of varix, ii. 572. Rietgen on the mode of performing the Caesarian operation, iii. 162 Rokitansky on internal strangulation, ii. 359. Roonhuysen on the use of the suture in vesico-vaginal fistula, ii. 191. Roots', Dr., case of human horns, iii. 405. Rose on the duration of syphilis under the non-mercurial treatment, and on the sub- sequent occurrence of secondary symp- toms, ii. 103. Roser on dislocation of the thumb from the metacarpal bone, ii. 234; on the cause of the difficulty experienced in reducing this dislocation, ii: 235; on the mode of re- ducing this dislocation, ii. 235. Rigby, Dr. on puerperal abscess, following!Rossi's mode of amputating at the knee contagious or adynamic puerperal fever, i. 60; on wounds of the uterus, as predis- posing to rupture in subsequent labours, ii. 531; on retroversion of the womb in the unimpregnated state, ii. 407 ; on exa mination by the vagina and rectum, and by the uterine sound, in retroflexion of the womb, ii. 409; on the symptoms of retroversion, ii. 410; on the mechanical support to the womb requisite after the reduction of the retroversion, ii. 414; on the circumstances authorising the Caesa- rian operation, iii. 155; on the propriety of not operating until after labour has commenced, iii. 158. Ritgen on the application of the sutures in the operation for lacerated perineum, ii. 39. Ritter's idea that boils depend on the re- tention of the animal refuse, i. 153. Robertson, Dr., on bronchocele as a variety of scrofula, iii. 389. Robertson's case of ligature of the carotid, ii. 508. Robinson, Dr., recommends the removal of the acromion and glenoid cavity in am- putation at the shoulder-joint, iii. 717. Robinson on the inhalation of ether prior to the extraction of teeth, iii. 768. Robison's, Dr., case of tetanus, i. 415s with the flap-cut, iii. 699. Rothmund on the treatment of umbilical rupture occurring after birth, ii. 345. Rousseau's mode of extirpating piles, ii. Roux on the introduction of a piece of bougie into an ossified artery after am- putation, i. 336; on the removal of the edges of the cleft in staphyloraphy, ii. 31; plan for bringing the edges of the cleft together, ii. 32; operation when the cleft is very large and complicated, ii. 34; fatal case from pneumonia, ii. 35; on the operation for lacerated perineum, ii. 39; on the application of the sutures, ii. 39; caseof artificial retention of faeces after the operation, ii. 40; on the suture in vesico-vaginal fistula, ii. 193; cases of extirpation of the womb, iii. 573 ; on the excision of joints, iii. 726; mode of ope- rating in excision of the wrist, iii. 734; case of excision of the heads of metatarsal bones, iii. 744; case of resection of the clavicle, iii. 764; case of resection of a rib, on account of necrosis, iii. 767. Rouyer on dislocation of the upper end of the radius forwards, ii. 232. Roy, De, on the making an artificial open- ing in the cheek in the operation for salivary fistula, ii. 148. Rochoux on hydrocele caused by gonor- Rudolphi on the causes of club-foot, ii rhea, iii. 222. Rodgers, Dr., successful operation for the establishment of a false joint in a case of anchylosis, i. 275; mode of operating in exarticulation of the fore-arm at the elbow, iii. 719. Rodriques, Dr., on the effeets of cupping- glasses in viper bites, i. 389. Rogers' case of trepanning the spine, l 590; on rism, ii. 564. Rognetta on the treatment of vesico-va- ginal fistula by compression with an elastic oval pessary, ii. 189; on disloca- tion of the astragalus inwards, n. 252; on the causes of splay-foot, n. 457. 446. Rudtorffer's plan to prevent re-union after the operation for united fingers and toes, iii. 17. Ruetenich's apparatus for fracture of the lower-jaw, i. 580. Ruhl's artificial leg, iii. 593 ; wooden leg, iii. 594. Rupture (hernia,) ii; 258. the tTeatment"ofbranching aneu- Russell on the appearances of white swell- ing on dissection, i. 305; on the treatment of scrofulous ulcers, ii. 53.( Russell, Dr.,confirms Celsus' observations on the innocuous qualities of the poison of serpents, when introduced into the mouth, i;390; on the symptoms produced 76* 90/2 ANALYTICAL INDEX. by the bite of a cobra di capello, i. 394; cases of fatal snake-bite, i. 395; on the treatment of snake-bites in India, with the Tanjore pill, i. 395; on the physical qualities of snake-poison, i.,395. Rust's opinion that the so-called lymph- swelling is an extravasation of lymph, i. 61; on injecting boiling water into a cold abscess, i. 105; division oferysipelas into true and false, i. 115; on the application of moist warmth in vesicular erysipelas and its varieties, i. 123; on incisions in pseudo-erysipelas, i. 124; explanation of the shortening of the affected limb in hip-disease incorrect, i. 284; explanation of the lengthening of the limb, i. 285; objects to the use of issues in hip-disease, i. 294 ; on warm bathing in, i. 296; on the mercurial treatment in, i. 296; on the general treatment of coxalgy, i. 296; on the treatment of abscesses at the hip, i. 298; advises their being opened by the actual cautery, i. 298; advises passing a seton through the joint, i. 298; explanation of wounds from the wind of a ball, i. 371; case of simple dislocation of the spine, i. 586; treatment of chronic ulcers of the foot hy the hunger-cure, ii. 48 ; treatment of syphilitic ulceration of the throat and palate, ii. 91; on the fric- tion-cure in syphilis, ii. 94; on the treat- ment of caries, ii. 118; mode of reducing dislocation of the humerus, ii. 224 ; me- thod of replacement of the dislocated fe-- mur, ii. 239, 240; on the nature of stran- gulation in ruptures, ii. 269 ; on ligature of the external iliac, ii. 538. Ruyer's case of exarticulation of metatarsal bones, with the diseased bones of the tarsus, iii. 710. Ruysch on the reduction of the prolapsed and ulcerated womb, ii. 375, Ryan's, Dr., case of wound of the neck, involving the oesophagus, i. 479 ; on the treatment of haemorrhage consecutive to extraction of a tooth, ii. 143. Sabatier advises the opening of abscesses at the hip with caustic, i. 298; more general application of the trephine, i. 454; plan for arresting bleeding from the intercostal artery, i. 492; apparatus for fracture of the neckof the femur, i. 623; internal opening of rectal fistula, ii. 162 ; reduction en masse, ii. 27.4; case of rupture of the lungs, ii. 360; prolapse of the womb, ii. 368; reduction of the prolapsed and ulcerated wound, ii. 375 ; treatment of. the prolapsed pregnant womb, ii. 375; excision of joints, iii. 727; mode of operating in excision of the head of the humerus, iii.,732. Sachs on the operation for the treatment of ingrowing of the nail, i. 224. Sacrum, fracture of, i. 595. Salamon's treatment of fractured clavicle, i. 605 ; operation for ligature of the com- mon iliac, ii* 533. Salemy's mode of amputating through the leg in its lower third, iii. 706. Salivary fistula, ii. 146. ■ ■ —calculus, iii. 123. Salle, De, on the treatment of gonorrhea, i. 197; on iodine in hard swellings of the testicle, ii. 101. Salmon's operation for the extirpation of the degenerated prolapse of the rectum, ii. 404; incautious use of enemata a cause of relaxed rectum, ii. 406; seat of stric- ture in the rectum, iii. 46. Sams' case of cerebral irritation preceding orchitis, consequent on gonorrhea, i. 201. Sanctorius' lithotritie instruments, ii. 285. Sandifort on congenital dislocation of the hip, ii. 207. Sanson on dressing the wound after the operation for rectal fistula, ii. 167; on the reduction en masse, ii. 274 ; on the retrac- tion of the tendons of the fingers, ii. 465; modes of'performing the recto-vesical operation for stone, iii. 344; mode of am- putating at the hip-joint with two flaps, iii. 698; at the shoulder-joint with the circular cut, iii. 716; mode of operating in excision of the knee-joint, iii. 740. Sarcocele, iii. 547; syphilitic, i. 200. Sarcomatous tumours, iii. 448. Sartorius on the section of the tendo Achillis in club-foot, ii. 453. Saucerotte on the operation for lacerated perineum, ii. 39; on the application of sutures, ii. 39; case of artificial retention of faeces after the operation, ii. 40. Sauter's. apparatus- for fracture of the neck of the femur, i. 624; on permanent ex- tension in fracture of the femur, i. 628 ; apparatus for permanent extension in fractures of the leg, i. 637; plan of reduc- ing dislocation of the humerus, ii. 225; d irections for the extirpation of the womb, iii. 570. Saviard on mortification from spurred rye, i. 7.4; on the healing the wounds of arte- ries, i. 330. Scabies, scabies spuria, ii. 63, 64. Scapula, fracture of* i. 601; resection of, iii. 762; with the elavicle, iii. 764. Scarification, iii.. 615. Scarpa on the healingof wounds of arteries, i. 330; experiments on the ligature of arteries, i. 335; experiment with the liga- ture and cylindenoflinen, i. 335; practice in wounded intestine, i. 509; on the pro- duction of callus, n 550; on the appear- ANALYTICAL INDEX. 903 ancespresented on post-mortem examina- tion, some time after the cure of an arti- ficial anus, ii. 155; on the nature of strangulation in ruptures, ii. 269 ; on the reduction en masse, ii. 274 ; on dilatation of the stricture in strangulated hernia without cutting, ii. 298; modification of the operation for femoral rupture, ii, 336; opposed to the radical cure of umbilical rupture by ligature, ii. 347; treats ischiatic rupture as enlarged pudic rupture in women, and enlarged perineal rupture in men, ii. .351; on the causes of club-foot, ii. 446; machine for dub-foot, ii. 451; views respecting the non-expansion of all the arterial coats in aneurism not always correct, ii 477 ; on the-application of the ligature, ii. 492; on the effects produced by the ligature on the arterial coats, ii. 493; on ligature of the external iliac, ii. 539; on the division ofthe prostate, iii. 312; on the diagnosis between scrofula and scirrhus, iii. 503 ; on the nature of scirrhus, iii. 509; case of lacteal swell- ing, iii. 532. Schaack on tapping a cold abscess with the trocar, and injecting red wine, or a solu- tion of bichloride of mercury or nitrate of silver, i. 106. Schallein's, von, prophylactic treatment of hydrophobia, i. 412. Schindler's artery-compressor, i. 331; on the more general application of the tre- phine, i. 454; mode of operating- in ex- cision of the lower jaw with the condyles, iii. 749; on the previous ligature of the carotid artery, iii. 750* Schmalkalden on the treatment of artificial anus, ii. 159. Schmalz on the effects of electrifying pa- tients in doubtful cases of mercurial dis- ease, ii. 112. Schmitt's obturator for vesico-vaginal fis- tula, ii. 189. Schmucker's case of concussion, i. 452; case of wound of the womb, i- 533 ; on ligature of the hernial sac for its-radical cure, ii. 283; case of spontaneous rupture of the ovarian cyst, iii. 214. Schneider's case of reduction of the con- secutive dislocation in hip-disease, i. 208; bandage for rupture of the tendoAohillis, Schonlein on the elimination of the mole- cular fibrin, i. 43. the lengthening of the limb complete rectal fistulae, ii. 169; on the use of the suture in vesico-vaginal fistula, ii. 191, 192; on congenital dislocation of the hip, ii. 207; on the causes of congenital dislocations, ii. 207; on incision of the hernial sac and the introduction of lint- tents, to effect the radical cure, ii. 283 ; indications when the operation for the radical cure is admissible, ii. 287; opera- tion for cartilaginous bodies in the shoul- der-joint, iii. 448; on the complication of nasal polypus with teleangiectasy,iii. 470; mode of amputating the penis near the pubic bones, iii. 544. Schreiner's mode of amputating, iii. 641. Sohuh's case of partial dislocation of the vertebrae, i. 587. Schumer never found any trace of inflam- mation in cartilage, i. 262. Schurmayer's apparatus for fraeture of the neck of the femur, i. 614. Schwann's opinion on the formation of new vessels, i. 323. Schwarz on the treatment of prolapse of the rectum, ii. 402. Schwenke on the lengthening of the limb in hip-disease, i. 285. Schwerdt's cleft-needle for the introduc- tion ofthe thread in staphyloraphy, ii. 33. Scoliosis, ii. 430. Scott's case of abseesses of the hip-joint, i. 282; plan of treatment of hip-dis- ease, i. 293; case of wounded stomach without protrusion, i. 521. Scoutetten's operation for the destruction of the matrix of the nail, i. 223; on the causes of club-foot, ii.447; on the section of the tendo Achillis in club-foot, ii. 453; mode of operating in exarticulating a bone, iii. 687; mode of operating for am- putation at the hip-joint, iii. 698; oval cut in partial amputation of the foot, iii. 705; mode of operating in exarticulation of the metatarsal bones,iii. 706; in exarticulation of the metatarsal bone of the great toe, iii. 709; in exarticulation of the toes, iii. 711 ; amputation at the shoulder-joint with the oval cut, iii. 716; mode of ope- rating in exarticulation of the metacarpal bones of the ring and little fingers, iii. 721;, oval cut in exarticulation of the middle metacarpal bone, iii. 721. Scrotum, frost-bitten, i. 144; sarcomatous, iii. 559; cancer of, iii. 548? Scultetus' artery-compressor, i. 331. Sebaceous tumors, iii. 434. S7nRhip-diseU^ of Sedillot's oblique cut in amputations, iii the head of the thigh-bone downwards and inwards in hip-disease, i. 286; case. of reduction of the consecutive disloca- tion i. 298; on the treatment of salivary fistula, ii. 147; apparatus for ligaturing 64v Segalas'"caustic-holder for stricture ofthe urethra, iii. 83. Seiler's modification of Dupuytren's en- terotome, ii. 158; on the nature of stran- 904 ANALYTICAL INDEX. gulation in rupture, ii. 269; on the opera- tion for strangulated ischiatic rupture, ii. 351; on the posterior labiafrupture,ii. 355. Selwyn's, Dr. Congreve, case of recovery from wound of the brain, i. 437. Senac on the globular structure of pus, i. 51. Senff on ligature ofthe hernial sac for its radical cure, ii. 283. Sennertus on aneurismal varix, ii. 547. Serres' case of aneurism of the basilar artery, ii. 516. Seton, introduction of, iii. 618. Se-utin on the treatment of compound frac- tures, i. 561; on the starch bandage in fractured ribs, i. 599; treatment of frac- ture of the humerus, i, 609; application of the permanent apparatus in fracture ofthe femur, i. 629 ; in fractures of the bones of the leg, i. 638; case of excision of the head of the femur, iii. 736; case of resection of the fibula, iii. 767. Severinus on cauterizing the tonsils with red-hot iron or caustic, i. 165. Sharp on tying the tonsils, i. 165; on the arrest of haemorrhage by nature, i. 329 ; on Cheselden's operation for stone, iii 315; mode of amputating at the shoulder- joint by the cireular cut, iii. 715. Shaw's case of extirpation of the tonsil, followed by superficial slough, alarming haemorrhage, and ligature of the carotid, i. 166; on dissection-wounds and their treatment, i. 385; case of fatal haemor- rhage during lithotomy from wound of dorsal artery ofthe penis, iii. 334. Sheldon's treatment of fractured oleoranon,! i. 613. j Shiptqn's experiments on wounded intes-: tine, i. 511. Shoulder, curvature of, ii. 463; exarticula-) tion of the arm at, iii. 711; excision of the head ofthe humerus at, iii. 731. I Shoval's case of gastrotomy for the remo-1 val of a knife from the stomach, iii. 106. Siebold, von, on tying the tonsils, i. 164; I case of yielding of the abdominal parie- tes, ii. 349; of extirpation of the womb, iii. 570; mode of amputating", iii. 641. Sigebert on mortification from spurred rye, i. 74. Signoroni's modification of Gerdy's opera- tion for the radical cure of rupture, ii. 284. Simpson, Dr., on cauliflower excrescence of the os uteri, iih 563; on the mode of using the speculum vaginae, iii. 565. Simpson, opinions of, relative to the forma- tion of pus, i. 46; adaptation of Thor- bern's staphylotome to the extirpation of the tonsils, i. 164. Sinogovitz on the nature of strangulation in rupture, ii. 269. Skin, cancer of, iii. 504. Skoda on the formation of new vesseh, i. 323. Skull, fractures of the, i. 428; fungus of, iii. 419. Smew's experiments on substances adapted for the immoveable apparatus for frac- tures, i. 554. Smellie, Dt., on the operation for lacerated perineum, ii. 39; on the application of the sutures, ii. 39. Smith on morbus coxae^ senilis, i. 289; on eolehicum in tetanus, i. 420; case of tre- panning the spine, i. 590; on some of the signs of fracture of the neck of the femur, i. 618; fracture-bed, i. 625; on the reduction of old dislocations, ii. 205, 206; case of congenital dislocation ofthe lower jaw, ii. 211; on the post-mortem appear- ances in congenital subacromial disloca- tion, ii. 227; on the resemblance between the congenital subcoracoid dislocation, and the partial dislocation ofthe humerus, and that caused by rheumatic affection of the shoulder-joint, or by unusual atrophy of the upper arm, ii. 228; on the treat- ment of teleangiectasy by inserting threads- dipped in solution of nitrate of silver, ii. 565; on the statistics of litho- tomy, iii. 271; case of large calculus, iii. 272'. Soemmering's preparation of fracture of the neck of the femur within the capsular ligament united by callus, i. 621 ; case of spontaneous cure of umbilical rupture, ii. 346. Softening, i. 66. Solander's, Dr., sufferings from exposure to cold, i. 145. Solera's operation for varix by cutting through the vein above and below, ii. 572. Solingen on amputating just above the ankle, iii. 671. Solly's case of gangrene, i.. 73; case of frost-bite, i. 145; case of recto-vesical operation for stone, iii. 344. Somme's case of relaxed rectum, with inva- gination of the mucous membrane, ii. 405. South's case of cold abscess, i. 58; of lymph-abscess, i. 61; on vesications filled with a blueish or blueish black fluid in eases of severe bruise, or when the ban- dages used in fracture are too tight, i. 68; case of mortification of the lower extremity from effusion of blood causing distention of the limb, i. 68; cases of mortification after fever, i. 69; of dry gangrene consequent on abdominal ty- phus, i. 69; of dry gangrene from or- ganic disease ofthe heart, i. 69; of arte- ritis without gangrene, i. 73; of noma in the adult, i. 76; on the sloughing state ANALYTICAL INDEX. 905 of stumps from want of power, i. 84; on inflammation ofthe cellular tissue, i. 86; on the tendency of serous membranes to adhesive inflammation, i. 88; case of ar- teritis, i. 89; on phlebitis, i. 92; on the cause of inflammation of the absorbents, i. 95; on earthy deposits in the absor- bents, i. 96 ; recommends the early open- ing of abscesses just beneath the skin,' and in glandular structures, i. 103; con- demnation of pressure and squeezing an abscess, i. 104 ; on opening an abscess, i. 105; amputation should never be per- formed while gangrene is in progress, i. Ill; on erysipelas and erythema, i. 115; case of degeneration of the cellular tis- sue ofthe forehead and face,i. 120; the con- stitutional and local treatment of simple erysipelas, i. 123; on the treatment of erythema symptomaticum by incisions, i. 124; on the application of the nitrate of silver in erysipelas, i. 124 ; on burns, i. 127; burns generally more dangerous than scalds, i. 127 ; complete immersion of a person in boiling water, fatal in ten or fifteen minutes, i. 127; persons whose entire surface has been charred by fire may live several hours, i. 127; danger of burns and scalds the greater, in refer- ence to the part injured, i. 127; use of flour in the treatment of burns, i. 133; treatment of burns and scalds, i. 135; in- ternal treatment of burns and scalds, i. 138; effects of the contraction of cica- trices, i. 139; case in which the cicatrix was dissected out, i. 140 ; parallelism of the effects of great degrees of heat and cold on the animal body, i. 143; mus- tard and liniment in the treatment of chilblains, i. 150; treatment of boils by free incision, i. 153; recommends the employment of general treatment in cases of boils, i. 153; rarity of car- buncle on the head, i. 156; treatment of carbuncle, i. 156; recommends the actual cautery in cases in which an arte- rial branch has been wounded in scarify- ing the tonsils, i. 160; directions for opening a tonsillar abseess, i. 161 ; treat- ment of enlarged tonsils, i. 162 ; amputa- tion ofthe tonsils, i. 165 ; opinion against excision ofthe uvula, i. 167; on the arrest of the secretion of milk, and its absorp- tion, 170; recommends abscess of the breast to be opened freely and early, i. 170 ; advantages ofthe proceeding, i. 170; condemns Langenbeck's plan of treating the fistulae, i. 171; treatment of fistulae, i. 172*-; case of chronic abscess of the breast, operated on by mistake for scir- rhus, i. 173 ; on retention of urine in se- vere gonorrhea, i. 178; on gonorrhea viru- lenta, a constitutional disease in certain persons, i. 183 ; frequency ofthe co-occur- rence of chancre and gonorrhea, i. 184 ; gonorrheal sore throat, i. 188; treatment of gonorrhea, i. 191 ; of painful erections and chordee, i. 192 ; arrest of haemor- rhage from the urethra, i. 192; treat- ment of gonorrhea in women, i. 193 ; on gleet, i. 194; on the infectious nature of, i. 194; condemnation of the practice of inoculating with gonorrhea to cure gleet, i. 196; on cubebs and copaiba in gonoT- rhea, i. 196 ; on balanitis, i. 198 ; treat- mentof balanitis, i 198 ; doubts swelling of the testicle being ever dependent on a syphilitic origin, i. 206 ; on congestion of the semen in the seminal tubes, as a cause of orchitis, i. 200 ; wasting of the tes- ticle, caused by inflammation, i. 202; treatment of orchitis, i. 203; of fungus of the testicle, consecutive to abscess, i. 203 ; of orchitis by compression, i. 203 ; on the application of compression, i. 205 ; results of compression, i. 205; case of metastasis of gonorrhea and inflamma- tion of the testicle to the brain, i. 206; origin of lumbar abscess from external violence, i. 209 ; distinctive character of psoas abscess from femoral hernia, i. 209 ; insidious progress ofthe disease, i.' 210; controverts Astley Cooper's opinion that the abscess should be allowed to take its course, i. 211 ; on issues in the treatment of lumbar or psoas abscess, i. 211 ; con- demns the practice of passing a seton through a lumbar abscess, and prefers puncturing it with a lancet, i. 212 ; treat- ment of the abscess, i. 213; paronychia cellulosa, i. 216; on the tendency ofthe tendinous and cellular whitlows to run into each other, i. 217; on the free inci- sionand subsequent treatment of whitlow, i. 220; directions for the treatment of the second variety of whitlow, i. 221; of the third variety of whitlow, and the neces- sity for free and deep incisions, i. 221 ; contravenes Cooper's statement that the application of a blister will often bring away the nail in cases of ingrowing^ i. 224; condemns Cooper's operations for the removal ofthe diseased nail, i. 225; on the evulsion of the nail in onychia maligna, i. 227; treatment of onychia by the destruction of the nail-gland with nitric acid, i. 228 ; absence of discrimi- nating signs between simple acute inflam- mation of the ligaments and rheumatism, i. 231 ; relaxation of the ligaments, i. 233; cases of abscesses external to the joint, i. 235; position ofthe limb during disease of the knee-joint, i. 235; non- malignancy of pulpy degeneration of the 906 ANALYTICAL INDEX. synovial membrane, i. 243; local treat- ment of synovial inflammation, i. 245; if suppuration ensue, the swelling should be punctured early, i. 246; use of blisters in promoting the absorption of the effused fluid, i. 246 ; on irritant applications in the treatment of chronic synovial inflamma- tion, i. 246; case of disease ofthe syno- vial membrane of the knee, attended with ■ evidence of fluctuation, in which the swelling was punctured without benefit,i. 247; considers that ulceration of cartilages differs from common inflammation ofthe synovial membranes, and of the spongy ends of bones, i. 262 ; opinion that the oc- currence of scrofulous disease in the joints has suspended the progress of some other and perhaps more serious disease else- where, i. 266 ; has seen the connecting medium in anchylosis composed partly of ligamento-fibrous, and partly of bony mat- ter, i. 268 ; on the ivory-like covering of the joint-surfaces of bones, i. 268 ; re- moval of the articular cartilages in old age, as the result of previous ulceration, i. 268; views on anchylosis differ some- what from those of Hunter, i. 269; on soft anchylosis from granulations, i. 269 ; cases of fibrous anchylosis, i. 270 ; of the complication of bony and fibrous anchy- losis, i. 271; on the constitutional treat- ment of hysterical affections of the joints, i. 278 ; on the pain on the inside of the knee in hip disease, i. 280 ; on the short- ening ofthe limb, i. 284; explanation of the lengthening of the limb, i. 286; on the appearances after death in hip-disease, i. 287; on the sympathetic pain in the hip from disordered bowels, i. 289 ; on the morbus coxae senilis, i. 289; the use of issues approved of, i. 294 ; the actual cau- tery or burning cylinders preferable in all cases where the limb is much lengthened, the muscles relaxed, and where there is great swelling from collection of fluid, i. 294 ; Brodie's plan of treating issues ap- proved of,i,295; management of abscesses at the hip, i. 299 ; diagnostic symptoms of the diseases of the knee, i. 302; diag- nostic sign for vertebral caries, i% 312; diagnosis between curvature of the spine from caries and that from rickets, i. 312; meaning of," quick union," J. 321; appli- cation ofthe tourniquet, i. 331; treatment of protracted oozing of blood, k 333 ; of epistaxis, i. 334 ; wounds of the pudic artery and artery of the bulb during the lateral operation for the stone, i. 334; treatment of wounded arteries in the thick fleshy parts of the hand or foot, i. 334 ; experiment on the carotid of a dog, i. 335; on the application of the ligature, i. 337;. ligature of large arteries above and below the wound, i. 337 ; necessity for cutting down upon a wounded vessel on the sound side of a limb, if nearer the artery than is the part wounded, i. 338; after-manage- ment of the ligature, i. 339 ; opinion that the ligature should be allowed to come away, as the result of the suppurating process, i. 340; management of a long- retained ligature, i. 340; on torsion, i. 344; treatment of bleeding ossified ves- sels, i. 352; on venous bleeding in opera- tions, i. 353; case of fatal venous bleed- ing during amputation of the breast, i. 353 ; use of bandages for wounds, i. 353 ; advantages and disadvantages of sutures, i. 358 ; number of sutures to be used, and the mode of their application, i. 360 ; ob- jections to stuffing a wound which must heal by granulation, i. 364; regeneration of the nerves, and the recovery of their function after division, i. 364; on the tearing or stripping down of large pieces of skin, i. 368; on torn wounds of the seal p, i. 368; on the sloughing which gene- ral ly follows extensive laceration of the skin of the limbs, i. 368; on extensive ecchymosis, and the means of diagnosis, when an artery of any material size is wounded, i. 369; treatment of the swell- ing, i. 369; danger of gangrene when a large artery has been wounded, from the distention of the soft parts, i. 369 ; cases of severe injury from small shot, i. 371; objects to the application of caustic in dis- section-wounds, i. 385; absorption of poisonous matter in dissection-wounds, i. 385 ; the most dangerous punctures those received in the examination of cases of simple or puerperal peritonitis,i. 386; con- sequences of dissection-wounds, i. 386; on viper-bites, and the requisite treatment, i. 389; doubts the disposition of hydrophobic patients to bite, i. 406; excision of the bitten parts in hydrophobia, i. 411; ex- cision of the scar, i. 412; on the proxi- mate cause of tetanus, i. 417; on the favourable termination of cases of tetanus which pass over the seventh day, i. 419; on long and free incisions on either side ofthe spine, and cauterizing the wounds in tetanus, i. 420; on the treatment of tetanus, i 420; on the nonrnecessity for sutures in wounds ofthe scalp, i. -123; on bruises of the coverings of the skull, fol- lowed by collections of fluid blood, i. 423; on poultices in bruises ofthe scalp, i. 426 ; treatment of injuries of the head when inflammation of the dura mater has set in, i. 426; bleeding at the ear, a sign of fracture at the base of the cranium, i. 429; nonrnecessity for the trephine in ANALYTICAL INDEX. 907 general, i. 430; on fracture of the frontal sinuses, i. 431; on apparent fracture and depression ofthe skull, i. 431; treatment of simple fracture with depression with- out the trephine, i. 431; importance of caution in the prognosis of wounds of the orbit, i. 437; propriety of opening abscess ofthe brain, i. 439; consequences of fo- reign bodies remaining in the brain, i. 439; chronic inflammation of the dura mater, i. 441; mercury in the treatment of inflammation of the brain, i. 443; mercury in compression, i. 446; removal of the ex- travasated blood after trepanning, i. 447; puncturing the dura mater, when the ex- travasation lies beneath, i. 447; the opera- tion of trepanning to remove effused blood, i. 448; state of the pulse in concussion, i. 449 ; treatment of concussion, i. 453 ; in- frequency of fungus of the brain after trephining, i. 454; trepanning in caries and necrosis of the skull, i. 457; distinc- tion between the trepan and the trephine, i. 463; operation of trephining, i. 463; trepanning the frontal sinuses, i. 464 ; re- moval ofthe depressed and detached bone, and of any points on the edge of the frac- ture, i. 464; bleeding from the middle meningeal artery, or from a sinus, i.j 465 ; after-treatment, i. 466 ; the twisted suture or thin pins in wounds of the face, j i. 470; wounds ofthe gristly passage of the ear, i. 472; on position in the treat- ment of wounds of the windpipe, i. 475 ; > on the treatment of such wounds, i. 476, 477 ; case of fistulous wound between the thyroid and cricoid cartilages, i. 477; on secondary haemorrhage in cut-throat, i. 477; management of fistulae resulting' from gun-shot wounds of the windpipe, with loss of substance, i. 478 ; examina- tion with the probe, etc, in penetrating j wounds ofthe chest, i. 481; condition of the lungs when the chest is opened, i. 481; on emphysema, i. 495; on the prac- j tice of sucking or pumping, to extract the air in the cavity of the chest, i. 496; case of wounded intestine, i. 507; treatment of wounded intestine witnout feculent dis- charge or prolapse, i. 517; rupture of the: liver, i. 525; rupture or laceration of the bladder in fracture of the pelvis, i. 528; rupture ofthe perineum, i 534; incising the spongy body of the penis, not always; a cause of loss of the power of erection, i. 535; objection to amputation of the penis, in lacerations of the cavernous bodies, l., 535 ; treatment of rupture of the urethra, i. 535; case of hydrocele, which wasj tapped, and the testicle supposed to be, wounded, i. 536; commends Abernethy sj practice in wounds of joints, i. 538; cases j of torn muscles, i. 543; causes of want of bony union in fractures of the neck of the femur, olecranon, patella, and os calcis, i. 551; non-necessity for bandages in frac- tures, i. 552; immoveable apparatus for fractures,i.553; on the position of the limb when stiffness of a joint is anticipated, i. 555; after-treatment of the fracture, i. 556; impropriety of setting a fracture before the lapse of a few days, i. 556; immediate management of fractured cla- vicle, and of oblique fractures, i. 557 ; on the antiphlogistic treatment in compound fracture, i. 559; exhibition of opium in compound fracture, i. 559; enlargement of the wound, and sawing off the project- ing portion of bone, i. 559; removal of splinters, i. 559 ; formation and treatment of abscesses during the progress of com- pound fractures, i. 560; treatment of wounded vessels, i. 560; mortification, and its treatment, general and local, i. 560; principal points to be considered in determining on the necessity for imme- diate amputation, i. 568; immediate and remoteconsequence of compound fracture, i. 570; sympathetic, symptomatic or irri- tative fever, i. 570; almost invariably sub- sides as suppuration is established, i.570; occurrence of secondary,constitutional, or nervous symptoms, i. 572; amputation must not be performed while the symp- tomatic fever continues, i. 572; the ad- vantages hoped for by the immediate removal of the injured parts, in prefer- ence to attempting to save them, i. 573; objects and occasional results of imme- diate amputation, i. 573; bending of bones, i. 576; case of extensive fracture ofthe bones of the face, i. 578; fracture ofthe lower jaw, i. 578; fracture of the os hyoides in persons who have been hung, i. 581; signs and rarity of occur- rence of fracture of the spinous process of the vertebrae alone, i. 582; occurrence of fracture of the vertebrae, without any great violence, i. 583; causes of fractured vertebrae, and on the injury the spinal cord sustains from the accident, i. 583; case of separation of the under surface of the second cervical vertebra from the inter-vertebral substance, without dis- placement, i. 586; treatment of fracture of the spinous processes, i. 589; on the attempt to set a fracture through the body of a vertebra, i. 589; treatment of frac- tured spine, i. 589; operation for trepan- ning the spine, i. 594; after-treatment, i. 594 ; fracture of the coccyx, i. 595; frac- tures of the hip-bone, and their danger from rupture of the bladder, i. 596; diag- nosis of fracture of the hip-bone, i. 596; 908 ANALYTICAL INDEX. impropriety of any operation to raise the depressed portions of bone, in fractures of the sternum, i. 598 ; case of wound of the heart caused by a fractured rib, i. 598 ; treatment of fractured ribs, i. 599; causes of fracture of the scapula, i. 600; symptoms of fracture of the acromion, i. 600; doubts the occurrence of fracture of the neck of the scapula, i. 601; case of fracture of the coracoid process, i. 601; fracture of the body, spine, and angle of the scapula, i. 601; treatment of fractured clavicle, i. 605; fracture of the greater tubercle of the humerus, i. 606; cases of fracture of the anatomical neck, i. 606; fracture ofthe surgical neck, i. 607; treatment of fracture of the hu- merus, i. 609; fracture of the condyles, i. 610; treatment of compound fracture of the humerus, i. 610; fracture of the neck of the radius, i. 611; treatment of fractures of the fore-arm, i. 613 ; of frac- tures ofthe olecranon, i. 614; in-locking of the broken ends of the bone, i. 618; case of separation of the head of the fe- mur from its neck by external violence, i, 619 ; preparation of fracture within the capsular ligament united by callus, i.621; simple and compound fractures of the femur, i. 628; treatment, of fracture of the femur, i. 628; of fractured patella, i. 633 ; means to be adopted for the adap- tation of the rectus muscle to the new condition of the patella, i. 634; compound fracture ofthe patella, i. 634; treatment of fracture of the bones of the leg, i. 638; case of compound fracture of the os calcis, i, 640; fracture of the phalanges of the toes, and treatment, i. 640; causes of the non-union of fractured bones, i. 642; rub- bing the ends of the broken bone together, i. 643; application of pressure* in false joints, i. 644; objects to external irrita- tion, i.644; remarks on Green's operation for an ununited fracture, ii. 21; uncer- tainty attending all operations on false joints, ii. 21; period at which the opera- tion for hare-lip should be performed, ii. 23; removal of the projecting teeth prior to the operation, ii. 23; position of the child's head during the operation, ii. 23; preference of the bistoury to scis- sors, ii. 24; the time the pins should be left, and their removal, ii. 26; on tear- ing out of the needles, ii. 26; use of ob- turators in cleft of the hard palate, ii. 27; application of strips of plaster in the treatment of ulcers, ii. 48; iodide of potassium and cod-liver oil in scrofula, ii. 53; treatment of sloughing chancre, ii. 89; of suppurating bubo, and of the sub- sequent ulcer, ii. 90; secondary syphilitic' sores, and their treatment, ii. 92; treat- ment of nodes, ii. 93; the friction-cure, ii. 95; proper mode of exhibiting mer- cury in the treatment of syphilis, ii. 103; possibility of infection from secondary syphilis, ii. 106; absorption of part of the dead bone in process of exfoliation, ii. 127; consequences of caries or necrosis in the mastoid process, ii. 132; necrosis of the vault of the skull, ii. 132; case of ex- tensive destruction of the vault of the skull, ii. 132; caries ofthe bones of the face, ii. 132; disease in bones from mer- cury and syphilis, ii. 133; inflammation and suppuration in the tooth-socket without caries, ii. 134; symptoms and treatment of sympathetic disease of the antrum, ii. 136; epulis, ii. 136; stopping a carious tooth, ii. 137; treat- ment of toothacH, ii. 138; hemorrhage consecutive to extraction of a tooth in cases of hemorrhagic diathesis, and its treatment by the actual cautery, ii. 141; case of consecutive hemorrhage, ii. 141; necessity for adopting preventive mea- sures immediately after the extraction of a tooth, when the hemorrhagic diathesis is known to exist, ii. 144; treatment of fistula of the parotid duct, ii. 149 ; biliary fistulae, ii. 151; case of artificial anus at the navel, ii. 157; of flow of colourless fluid from the navel, ii. 157; operation for rectal fistula, ii. 166; ligature of rec- tal fistula, ii. 169; incomplete internal urinary fistula, ii. 175 ; operation for the division of the stricture in great narrow- ing ofthe urethra, ii. 184; for recto-vesi- cal fistula, ii. 186; diagnosis of disloca- tions, ii. 201; dislocations from muscular action, ii. 201; reduction of dislocations, ii. 203; of old dislocations, and on the necessity of caution in practising exten- sion, ii. 201; recurrence of dislocations after reduction from exhaustion of the muscular power, ii. 205; auxiliary treat- ment in the reduction of dislocations, ii. 206; reduction of dislocation of the lower jaw, ii. 210; difficulty of keeping the dis- located scapular end of the clavicle re- duced, ii. 220; repeated dislocation ofthe femurin the same person, ii. 236; English practice in compound dislocations of the ankle, u. 251; reducing the dislocation of the astragalus, ii. 253; case of dislocation of the os calcis. ii. 255; on certain forms of raptares, ii. 259; presence of the sac in vesical and ccecal ruptures, ii. 259; causes of stricture in the body of the sac, ii. 260; hour-glass contraction of the hernial sac, ii. 261; occasional rupture of one side of . the first metatarsal bone, iii. 723 ; of thej other metatarsal bones, iii. 723; exarticu- j lation of ihe fingers, at their junction with the metacarpal bones, and at their own] joints, iii. 723; Dupuytren and Lisfrancj on exarticulation of the middle and ring| fingers, iii. 723 ; Barthelemy on the sec- tion ofthe palmar aponeurosis after exar- ticulation of the fingers from the meta- carpal bones, iii. 723 ; mode of operating! in exarticulation of the joints of the fin-j gers from each other, iii. 723; with two flaps, iii, 721; Lisfranc's flap operation, iii. 724: statistics of amputations, iii. 724; Immediate Amputation, iii- 724; im- portance of the question, iii. 724 ; South on the comparative danger of primary and secondary amputation in severe in- juries ofthe thigh, iii. 724; South's con- clusion in favour of primary amputation, iii 724; South on the minor danger in injuries of the leg or upper extremities, and the consequent propriety of imme- diate amputation, iii. 724; John Hunter's preference of secondary amputation, iii. 725 ; John Hunter's objections to primary amputation in severe injuries of the ex- tremities, iii. 725; Astley Cooper's opinion in favour of immediate amputation in such cases, the constitution then having but one shock to sustain, iii. 725 ; RutheT- ford Alcock on the difference ofthe shock to the constitution in such cases, when occurring in civil life, and on the field of battle, iii. 725; excision of the joints, iii. 726; first performed on the knee- joint, iii. 726; afterwards extended to the other joints, iii, 726; Filkin, Vigaroux, David, White, Bent, Orred, Park, Mo- reau, Graefe, and Davie's cases, iii. 726; Sabatier, Percy, Roux, Moreau, Larrey, Guthrie, Syme, Textor, and Jaeger on the excision of joints, iii. 726; Wachter, Vermandois, Kohler, and Chaussier's ex- periments, iii. 727; objections to this operation as compared with amputation, iii. 727; advantages of the operation principally referable to the joints of the upper extremities, iii. 727 ; not so great in operations on the other joints, iii. 727; statistics of Jaeger, Syme, and Moreau's cases, iii. 727; Crampton on the ex- cision of joints, iii 728; cases in which excision of the ends of bones is pre- ferable to amputation, iii. 728; contra- indications to the operation, iii. 729; mode ofoperating, iii. 729 ; direction and extent of the incision in the skin, iii. 729; ex- cision of the diseased bone, iii. 729; ex- tent of bone required to be removed, iii. 729 ; instruments for excising the ends of bones, iii. 730; arrest ofthe subsequent haemorrhage,iii. 730; dressingthe wound, iii. 730; after-treatment, iii. 730; untoward occurrences during the after-treatment, iii. 731; after-bleeding, iii. 731; abscesses, iii. 731; fistulous passages, iii. 731; necrosis of rare occurrence after this operation, iii. 731; after-treatment of the sawn ends of the bone, iii. 731; excision at the shoulder- joint, iii. 731; mode of operating in ex- cision ofthe head of the humerus, iii.732; C.White, Orred, Bent, Sabatier, Moreau, and Syme's modes of operating, iii. 732; motions of the arm subsequent to the ope- ration, iii. 732; excision of the elbow-joint, iii. 732; Moreau's mode of operating, iii. 733; Dupuytren and Syme's modes of operating, iii.733; Moreau on the division of the ulnar nerve in this operation, iii. 733; Dupuytren, Crampton, Jaeger, and Syme recommend its preservation, iii. 734; Jaeger's mode of operating, iii. 734; 920 ANALYTICAL INDEX. condition of the arm after excision of the elbow-joint,iii.734;Cramptonand Syme's cases, iii. 734 ; excision of the wrist-joint, iii. 734; Roux and Jaeger's modes of operating in excision of the lower ends of the radius and ulna, iii. 734; dressing the wound and after-treatment, iii. 735; Du- bled and Velpeau's operations, iii. 735; Butt's case of excision of part of the ne- crosed ulna, iii. 735 ; excision of the hip- joint, iii. 735; mode of operating, iii. 735; by a simple longitudinal cut, iii. 736; by the formation of a flap, iii. 736 ; by Tex- tor's oval cut,iii.736; dressing the wound, iii.736; White, Carmichael, Oppenheim, Hewson, Seutin, and Textor's cases, iii. 737; C. White on excision of the head of the femur, iii. 737; A. White and Fer- gusson's cases of excision of the head of the femur, iii. 738; excision of the knee- jaint, iii. 740; Moreau, Park, Mulder, Sanson, Begin, Jaeger,and Syme's modes of operating, iii. 740; Jaeger's operation preferred, iii. 740; Moreau, Park, and Jaeger on the mode of union after the operation, iii. 740; Syme on the treatment after the operation, iii. 741; A. White's case of compound dislocation of the femur behind the leg, iii. 741 ; excision of the ankle-joint, iii. 742; Moreau, Jaeger, Mulder, and Kerst's modes ofoperating, iii. 743; South on excision of the ankle- joint, iii. 743; dressing the wound, and after-treatment, iii. 743; excision of the joints of the metacarpus and metatarsus, iii. 744 ; mode of operating, iii. 744 ; af- ter-treatment, iii. 744 ; Textor, Kramer, Roux, and Fricke's cases, iii.744; excision of the lower jaw, iii. 745; cases requiring the operation, iii. 745; circumstances admitting a favourable result, iii. 745; priority of claim as originator of the operation, iii. 745; Tyrrell's case of ne- crosis of the lower jaw, iii. 745; excision if the middle of the lower jaw, iii. 746; mode of operating, iii. 746 ; retraction of the tongue, iii. 746 ; Dupuytren, Graefe, and Astley Cooper's cases, iii. 747; re- moving a portion of the side of the lower jaw without the condyle, iii. 747; mode of operating, iii. 748 ; Deadrick, Mott and Wardrop's cases, iii. 748; excision ofthe lower jaw withitscondyles,i\i.lAS; Mott, Schindler, von Graefe, Syme, Jaeger, and Cusack's modes of operating, iii. 749; Mott, von Graefe, Dzondi, Jaeger, and Schindler on the previous ligature of the carotid artery, iii. 750; White's case of excision of the lower jaw, iii. 750; Graefe and Mott's cases of exarticulation of one side of the lower jaw, iii. 751; Cusack on the non-necessity of tying the carotid artery prior to the operation, iii. 752; Cusack's cases of exarticulation of the lower jaw, iii. 752; Liston's mode of ope- rating, iii. 753; Perry's case of necrosis of the lower jaw, iii. 753 ; resection of the upper jaw, iii. 753; cases in which the operation is indicated, iii. 753; Dupuy- tren's cases of extirpation of the upper jaw doubted by Gensoul, iii. 754; Ako- luthus' case, iii.754; Dr.T. White's case of almost complete extirpation ofthe upper jaw, iii. 754; mode of operating, iii. 755; section of the skin and muscles, ac- cording to Gensoul and Dieffenbach, iii. 755; Lizars the first to recommend the entire removal of the upper jaw, iii. 755; his description of the proposed operation, iii. 755; Lizars' cases in which he at- tempted to perform the operation, but failed on account of the hemorrhage, iii. 756; Lizars' cases in which he performed the operation, iii. 756; Gensoul's case of extirpation of the superior maxillary bone, iii. 756; cutting away the diseased jaw, iii. 757; Heyfelder's operation for the resection of both jaws, iii. 758 ; Syme, Liston, and Fergusson's modes of ope- rating, iii. 758; O'Shaugnessy's case of removal ofthe upper jaw, iii. 759; Het- ling's case of osteosarcoma of the jaws, in which he removed part of the upper, and part of the lower jaw, iii. 760; Liston on the prospect of ultimate success in this operation in cases of malignant disease, iii. 761; dressing the wound, and after- treatment, iii. 761; dangerous symptoms which may occur after the operation, iii. 761; recurrence of the disease, iii. 761; resection of the scapula (blade-bone,) iii. 762; von Walther's mode of operating, iii. 762; Haymann's operation, iii. 762; Liston, Janson, Luke, Syme, and Travers' cases, inwhich resection ofthe scapulawas performed, iii. 762; James' case of tear- ing away the arm and scapula by ma- chinery, iii. 763; resection of clavicle (collar-bone,) iii. 763; cases requiring the operation, iii. 763; mode of operating, iii. 763; Cuming, Meyer, Roux, Warren, Mott, Travers, and Chaumet's cases in which resection of the clavicle was per- formed, iii. 764; resection ofthe scapula and clavicle together, iii. 764 ; Mussey, M'Clellan,Gilbert,and Fergusson's cases iii. 765; Fergusson's mode of operating, iii. 765; Gaetani Bey's case of resection of the scapula, and of the acromial end of the clavicle, iii. 766; resection of the ribs, iii. 766; mode of operating, iii. 766; in compound comminuted fracture, iii. 766; Textor and Warren's cases of re- section of a rib, iii. 766; Dixon's resec- ANALYTICAL INDEX. 921 tion of the cartilage of a rib, iii. 767; Roux's case of resection of rib on account of necrosis, iii. 767; resection of the fibula, iii. 767; Seutin and Malgaigne's cases, iii. 767; resection of other bones, iii. 767. Sutcliffe's performance of the Taliacotian operation, iii. 577. Sutton's, Dr. case of a foreign body re- maininga long while in the windpipe, iii. 112; case of ovarian dropsy, with dis- , charge of hair by the wound made in tap- ping, iii. 215. Swan's case of fracture of the neck of the femur within the capsule united by bone, i. 621; case of division of the peroneal nerve, iii. 636. Swediaur proposes the word Menorrhagia in lieu of gonorrhea, i. 174; objections to the use of corrosive sublimate in cases of syphilis in infants, ii. 106. Synovial membrane, inflammation of. See Inflammation of the joints. Syme on inversion of the foot in fracture of the neck of the femur, i. 618; distinguish ing character of caries,ii. 115; characters of caries, ii. 115; treatment of caries, ii. 119; case of destruction of the bones of the face, ii. 133; salivary calculi,ii. 150; prolapsus ani, ii. 398; characters of prolapsus ani, ii. 399; diagnosis between prolapsed rec- tum, and haemorrhoids and intus-suscep- tion, ii. 399 ; case of wry-neck, ii. 422 ; distorted position of the head caused by caries between the occiput and atlas liable to be mistaken for wry-neck from muscular contraction, ii. 422 ; wry-neck a cause of lateral curvature, ii. 431; sec- tion of muscles in spinal curvature, ii. 439; carotid aneurism, ii. 507; removal of internal piles by ligature, ii. 583; seat of stricture in the rectum, iii. 46; case of j subcutaneous section for foreign bodies in J joints, iii. 447; prefers Liston's flap-opera- j tion for the thigh, iii. 660; objects to am- putation through the shaft of the femur, and recommends amputation through the condyles, or trochanters, iii. 660; for- mation of conical stumps in flap-amputa- tions of the thigh, iii. 667 ; amputation through the epiphyses of the femur, iii. 668; mode of amputating at the ankle- joint, iii. 702; advantages of this opera- tion, iii. 702; excision of joints, iii. 726; statistics of cases, iii. 727; mode ofopera- ting in excision of the head of the hu- merus, iii. 732; in excision ofthe elbow- joint, iii. 733; recommends the non-divi- sion of the ulnar nerve in that operation, iii. 734; cases of excision of the elbow- ioint, iii. 734; mode of operating in ex- cision of the knee-joint, iii. 740; treat- Vol. in.—78 ment after the operation, iii. 741; mode of operating in excision of the lower jaw with the condyles, iii. 749; in resection of the upper jaw, iii. 758; case of resection of the scapula, iii. 762. Symond's, Dr. case of removal of the in- verted womb by ligature, ii. 388. Symphysiotomy, iii. 165. Syphilis ;—question of its identity with go- norrhea, i. 183; observations and experi- ments of Hernandez and Ricord, i. 183; Hunter on the identity ofthe two poisons, i. 184; accounts for the different effects of the same poison by the gonorrhea pro- ceeding from a secreting surface, and the chancre being formed on a non-secreting surface, i. 184; South on the frequency of the co-occurrence of chancre and gonor- rhea, i. 184; Benjamin Bell denies the identity of gonorrhea and syphilis, i. 185; Hernandez' experiments on the subject, i. 185; ulcers produced by in- oculating with gonorrheal virus not syphilitic, i. 186; Ricord's observations and experiments, i. 186; Ricord's in- ferences from the results of the inocu- lation with gonorrheal matter, i. 186; venereal ulcers, ii. 70 ; distinguished as primary and secondary, ii. 71; causes, ii. 71; South on the inappropriate use of the terms "venereal ulcer" and "chancre" as synonymous, ii. 71; John Hunter on the two modes in which the venereal poison affects the system, ii. 71 ; Law- rence on the progress of syphilis from one part ofthe body to another, ii. 72; the ope ration of the venereal contagion requires a peculiar delicate structure of the part af- fected, or a deprivation of its cuticle, i. 72; symptoms of chancre, ii. 72; characters of the pus secreted by venereal ulcers, ii. 72; John Hunter and Ricord on the period at which chancres appear after infection, ii. 72; John Hunter, on the symptoms of chancre, ii. 72; Lawrence on the pro- gress of ulceration in a syphilitic sore, ii. 72; Lawrence on the five kinds of syphilitic sores, ii. 73; the pus of the ulcer the special vehicle of the venereal contagion, ii. 73 ; Hunter's experiments by inoculating with the matter of gonor- rhea and chancre, ii. 73; Ricord on inoculation for the purpose of distin- guishing syphilitic sores, whether pri- mary or secondary, ii. 74 ; buboes the first symptoms of general syphilis, ii. 75; may be idiopathic, or sympathetic, ii. 75; symptoms, progress, and termina- tions, ii. 75; John Hunter on the true venereal buboes, ii. 75; Ricord on the seven kinds of buboes, ii. 75 ; Hunter and Ricord on the existence of syphilitic 922 ANALYTICAL INDEX. buboes without primary sore, ii. 76;'■ general syphilis attacks specially either, the skin, mucous membranes, or bones, ii. 77; John Hunter on the continu- ance of the constitutional irritation from lues, independent of continued absorp- tion, ii. 77; inflammation of the mucous membrane of the throat, ii. 77; symp- toms, appearances, and results, ii. 78; venereal eruptions, ii. 78; symptoms, ii. 78; Lawrence on the four kinds of syphilitic eruptions, ii. 78; herpetic) eruptions, rhagades, verrucae, and con- dylomata, ii. 79; John Hunter and Ri-j cord on the non-infectious character of the pus from a secondary syphilitic sore, ii. 79; symptoms and results of syphilis j in the bones, ii. 80; modifications of the! symptoms of syphilis, ii. 80; primary1 syphilitic ulcers no decided external character, ii. 81; Abernethy on pseudo- syphilis, ii. 81; Abernethy on the means of distinguishing between true and false syphilis, ii. 82; Carmichael's objections to the terms, syphilis, syphiloidal, and pseudo-syphilis, ii. 82; Carmichael bases his arrangement of venereal complaints] on the character of the eruption, ii. 82; Ricord on the causes of the varied ap- pearances of chancre or primary syphi-J tide sore, ii. 82; differences in secon- dary syphilis, ii. 84; prognosis, ii. 84; John Hunter on the relative rapidity of i cure of gonorrhea, chancre, and lues ve-| nerea, ii. 85; Abernethy on the. occa- sional spontaneous healing of chancre, ii. 85; John Hunter on the relapse of ulcers after chancres have cicatrized, ii. 85; treatment of syphilis with mercury, ii. 86; in treating chancre, an especial indication to prevent general syphilis, ii. 86; local treatment, ii. 86; Ricord on the destruction of the ulcer by the nitrate of silver, ii. 86, internal exhibition of mercury, ii. 86; Lawrence on the exhi- bition of mercury in cases of chancre, and on the rarity of the occurrence of secondary symptoms when mercury has been used, ii. 86; Lawrence on the ex- tent to which the use of mercury may be pushed, ii. 87; Green on the use of mer- cury in syphilis, and on the forms in which it should be employed, ii. 87; cir- cumstances requiring the local exhibition of corrosive sublimate; ii. 88; Delpech on frictions with the ung. hyd. cin. in primary syphilis, ii. 89; iSouth on the treatment of sloughing chancre, ii. 89 ; mercury not to be used either internally or externally under such circumstances, ii. 89; mercury should be exhibited for some time in smaller doses after the chancre has cicatrized, ii. 89; treatment of buboes, ii. 89; tendency of idiopathic buboes to suppurate, ii. 90; treatment of tfie remaining ulcer, ii. 90; treatment of the indurated bubo, ii. 90; mode of open- ing suppurating buboes, ii. 905 Fer- guson, Fricke, Reynaud, and Ricord on the treatment of buboes, ii. 90; South on the treatment of suppurating bubo, and of the subsequent ulcer, ii. 90; treatment of general syphilis by mercury, ii. 91; ex- ternal employment of mercury, when re- quired, ii. 91; sublimate baths, ii. 91; the internal exhibition of mercury pre- ferable in ordinary syphilis, ii. 91; local symptoms require special treatment, ii. 91; Rust's treatment of syphilitic ulce- ration of the throat and palate, ii. 91; treatment of syphilitic eruptions, ii. 92; treatment of the granulations by caustic or the knife, ii. 92; of syphilitic diseases of the bones, ii. 92; mercurial fumiga- tion in syphilitic ulceration of the tonsils and pharynx, ii. 92; South on secon- dary syphilitic sores and their treat- ment, ii. 92; South on the treatment of nodes, ii. 92; necessary to vary the mer- curial preparations in use according to constitution, and other circumstances, ii. 93; >'tarke on the phosphor, hydrarg. von Graefe on the iodide and bromide of mercury, and Mendaga and Parent on the hydrarg. cyan., ii. 93; salivation not necessary for the cure of the venereal disease, ii. 93; treatment of salivation, ii. 94; treatment of old cases of vene- real disease, ii. 94; Louvrier and Rust on the friction-cure, ii. 95; cases in which the friction-cure is indicated, ii. 95; cases in which it is contra-indicated, ii.95; South on the friction-cure, ii. 95; mode of em ploy ing it, ii. 95; Wedemeyer, Rust, and South on the number of times the frictions may require to be practised, ii. 96; the order in which the rubbings-in are to be conducted, ii. 96; symptoms which occur during this treatment, ii. 97; the Montpellier modification of the friction-cure condemned, ii. 97; treat- ment to be adopted, if the salivation or critical sweating be suddenly suspended, ii. 97; occurrence of spasmodic or ner- vous symptoms, ii. 97; subsequent treat- ment, ii. 97; Weinhold's mercurial cure, ii. 97; mode of employing it, ii. 98; Zittmann's decoction, ii. 98; mode of exhibiting it, ii. 98: formula for Zitt- mann's decoction, ii. 99 ; the Arabian treatment, ii. 99; Dzondi's treatment, ii. 100; the preference given to the use of Zittmann's decoction, ii. 100; treatment of syphilis without mercury, ii. 100; ANALYTICAL INDEX. 923 various modes of treating secondary symptoms without mercury, ii. 100; Pit- cairn, Chrestien, and Niel on gold and its preparations inprimaryand secondary syphilis, ii. 101; Ricord, Eusebede Salle, Lallemand, Biett,Pailland, Wallace, Dr. Williams, Judd, Tyrrell, Ebers, von Hasselberg, and Hacker on iodine and hydriodate of potash in gonorrhea and general syphilis, ii. 101; Forster on the cure of syphilis by the chloride of gold and soda, ii. 102; treatment of syphilis without mercury in England, ii. 102; Hill, Hennen, Rose, Guthrie, and Thom- son on the duration of the disease under this treatment, and on the subsequent occurrence of secondary symptoms, ii. 103; South on the proper mode of exhi- biting mercury in the treatment of sy- philis, ii. 103 ; objections to the treatment withoutand with mercury, ii. 103; syphilis in infants, ii. 103 ; causes of infection, ii. 104; Evanson and Maunsell on the com- munication of syphilis to the foetus in the womb, ii. 104; Huguier on the period at which syphilis shows itself after birth, ii. 104; infection of a child by a syphi- litic nurse, ii. 105; Dycktnan's assertion that the child may be infected by milk of a diseased nurse, ii. 105; Hunter, Law- rence, and Todd's cases of diseased chil- dren infecting the nurses, ii. 105; Colles doubts whether the child can infect the nurse, unless she have ulceration of the nipple, ii. 105; Evanson and Maunsell on the symptoms of syphilis in infants, ii. 106; Lawrence on syphilitic iritis, and ulceration about the anus in infants, ii. 106; prognosis, ii. 106; Evanson and Maunsell on the treatment of syphilis in infants, ii. 106; Swediaur and Bacot ob- ject to the use of corrrosive sublimate in such cases, ii. 106; Hey, Lawrence, Hunter, Ricord, and South on the possi- bility of infection from secondary syphilis, ii. 106. Taylor on the rarity of carbonate of lime calcoli, iii. 242; on calculi of children, iii. 248; hour-glass calculi, iii. 272. Teeth, caries of, ii. 133; extraction of, ii. 138; replacement of, iii. 596; supernu- merary, iii. 597. Telangiectasy, ii. 559; congenital, ii. 559; characters, ii. 559; fungous growths after rupture of the swelling, ii. 559; na- ture ofthe disease, ii. 559; complications, ii. 560; telangiectasis lipomatodes, ii. 560; causes, ii. 560; always a local disease, ii. 561 ; prognosis, ii. 561; treat- ment, 561; ii. by compression, ii. 561; Abernethy on compression, ii. 561; by extirpation with the knife, ii, 561; with the ligature, ii. 562; advantages of the ligature, ii. 562; Lawrence, Brodie, and South on the application of the ligature, ii. 562; destruction of teleangiectasy by caustic, ii. 563 ; South on caustic in te- leangiectasy, ii. 564 ; various remedies to induce inflammation and suppuration in the diseased growth, ii. 565; Pattison, Smith, and Tyrrell's cases, ii. 565; tying the principal trunk supplying the diseased growth, ii. 566; if the teleangiectasy be seated on the extremities, and incurable, amputation must be performed, ii. 566; Pauli on the tattooing of moles on the skin, ii. 566. Temporal artery, ligature of, ii. 515. Tessier proves that animals are subject to gangrene from the use of spurred rye, i. 75. Testicle, inflammation of, orchitis, hernia humoralis:—Benjamin Bell on alternate swelling of the testicle, i. 199 ; causes—gonorrhea as a cause, i. 199; epididymitis, i. 129; Hunter on the period when swelled testicle supervenes, i. 199; may be a symptom of general syphilis, i. 199; Hunter says swelling of the testicle is from sympathy, and not from syphilis, i. 199 ; Astley Cooper and Ricord describe syphilitic swelling ofthe testicle, i. 200; external injury, cold, and violent exertions may induce orchitis, i. 200; Hunter on gout as a cause, i. 200 ; Astley Cooper mentions enlargement of the prostate in old age, inflammation of the neck of the bladder, a stone passing through the ureter, or pressing on the commencement of the urethra, as causes of swelled testicle, i. 200; South on con- gestion of semen in the seminal tubes as a cause of orchitis, i. 200; symptoms and terminations of orchitis, i. 201; suppura- tion to be feared when the pain is throb- bing, i. 201 ; induration not an uncorn: mon termination, i. 201; gangrene rare, i. 201; Astley Cooper on the symptoms and progress of orchitis, i. 201; occa- Tait's case of ligature of both the external itiacs, ii. 537. Taliacotian operation, iii. 577. Tanchou's caustic-holder for stricture of the urethra, iii. 83. Taramelli's case of hernia of the vermi- form appendix, ii. 260. Tarsal bones, exarticulation of, iii. 703. Tarsus, fracture of, i. 639; dislocation of the bones of, ii, 251. Tavignot on the use of oil varnish on starch bandages in fractures in young children, i. 554; subcutaneous ligature ot the superficial arteries, ii. 503 ; treatment of spina bifida by closure of the sac, in. 190. 924 ANALYTICAL INDEX. sionally preceded by great irritation of the brain, i. 201; Sam's case of cerebral irritation preceding an attack of orchitis, consequent on gonorrhea, i. 201; subsi- dence of orchitis generally followed by a return of gonorrhea, i. 202; Astley Cooper on adhesion and thickening of the tunica vaginalis,!. 202 ; suppurative rare when the inflammation is sympathetic, i. 202; Astley Cooper on suppuration of the testicle, i. 202; bursting of the abscess sometimes followed by a fungous growth, i. 202; symptoms and progress of orchitis serve to distinguish it from any other disease, i. 202; S. Cooper's case of or- chitis, simulating strangulated rupture, i. 202; swelling ofthe testicle from blows takes place very rapidly, i. 202.; Astley Cooper and South on wasting of the tes- ticle, caused by inflammation, i. 202; Astley Cooper on the more frequent seat of the disease in the globus major, i. 202; treatment of orchitis, i. 203; South on the treatment, i. 203 ; treatment of suppura- tion and abscess of the testicle, i. 203; South on the treatment of fungus of the testicle, consecutive to abscess, i. 203; treatment of induration, i. 203; occasional termination of induration in sarcoma and scirrhus, i. 204; treatment of orchitis from cold or external injury, i. 204; Fricke on compression in orchitis,!. 204; South on the treatment by compression, i. 204; mode of application of compres sion, i. 204; South on the application of compression i. 205; subsequent treat- ment, i. 205; South on the results of com- pression,!.205; South's case of metastasis of gonorrhea and inflammation of the tes- ticle to the brain, i. 206; great care re- quired in the application of the plasters for compression, i. 207; the advantages of compression, according to Fripke, i. 207; wounds of, and of the spermatic cord, i. 536; treatment of the accompanying inflammation, i. 536; if the testicle be destroyed, either by the injury or the sub- sequent suppuration, it must be removed, i. 536; wounds ofthe oord, involving the nerves and vessels of the testicle, cause its shrivelling or deeay, i. 536 ; South's case of tapping a hydrocele, with sup- posed wound ofthe testicle, i. 536. Testicle, cancer of, iii. 547; sarcocele, iii. 547; cystie swelling of, iii. 553; hyda- tids of, iii. 553; fungus of, iii. 554; scrofulous swellings of, iii. 554 ; syphi- litic swellings of, iii. 554; medullary fungus of, iii. 554; extirpation of, iii. 556 ; undescended testicle, and its treat- ment, iii. 557. Tetanus, i. 414 ; varieties, i. 415; Travers on traumatic tetanus, i. 415; Travers on the period of accession ofthe disease after the receipt of the injury, i. 415 ; Dr. Ro- bison's case, i. 415; Brodie, Sir James M'Grigor, and Blane on the period of accession of tetanus after the receipt of the injury, i. 415; three stages of tetanus, i. 416; symptoms, i. 416; Lawrence and Abernethy on a costive state of the sys- tem preceding tetanus, i. 416; Hunter on the cause of death in, i. 416; state of the intellect in, i. 417; Samuel Cooper's case of chronic tetahus of five weeks'duration, i. 417; proximate cause, i. 417; Froriep, Friedrich, Curling, South, and Lawrence on the proximate cause, i, 417; remote oauses, i. 417 ; John Hunter, Travers, arid Samuel Cooper on the causes, i. 418; Dr. Bardsley on the diagnosis of tetanus from hydrophobia, i. 418; prognosis always extremely unfavourable, i. 418; Dr. O'Beirne and Hennen on its fatal character, i. 419; South on the favourable termination of cases which pass over the seventh day, i.,419; treatment, i. 419; Larrey and Dupuytren on amputation in, i. 419 ; general treatment, i. 419; Klein and Treswart on the use of prussic acid in, i. 419; Smith on colchicum in, i. 419; South on long and free incisions on either side of the spine, and cauterizing the wounds, i. 420; exhibition of opium in, i. 420; South on the treatment of, i. 420. Textor on dislocation of the head of the thigh-bone downwards and inwards in hip-disease, i. 287; case of reduction of the consecutive dislocation^ i. 297; on the arrest of haemorrhage by nature, i. 329; effects of torsion, i. 343; dressing the wound after the operation for rectal fistula, ii. 167; ligature of the femoral below Poupart's ligament, ii. 539; cutting away the tunica vaginalis, iii. 230; mode of amputating the thigh with a flap from the outer side, iii. 660; from the inner side, iii. 660; mode of operating in exarticu- lation of the fore-arm at the elbow, iii. 719; excision of joints, iii. 726; case of excision of the head of the femur, iii. 737; of excision of the head of a meta- carpal bone, and of the os magnum, iii. 744 ; of resection of a rib, iii. 766. Theden's apparatus for fracture of the neck of the femur, i. 623; ligature of the her- nial sac for its radical cure, ii. 283* Thevenin on dilatation of the stricture in strangulated hernia without cutting,ii.298 Thierry on torsion of arteries, i. 341, ii. 501; mode of practising torsion, i. 342. Thigh, artificial, iii. 594; amputating through, iii. 656; exarticulation of at the hip-joint, iii. 688. ANALYTICAL INDEX. 925 Thilenius' case of reduction of the con- secutive dislocation in hip disease, i. 297; division of the tendo Achillis in club-foot, ii. 457. Thomson's, Dr., observations on the varia- tion of the current of the blood through the capillaries, resulting from the appli- cation of different substances, i. 38; mor- tification from the use of spurred rye, i. 74; objections to John Hunter's views on " quick union," i. 319; splitting ofthe ball in gun-shot wounds by the sharp edge of a bone, i. 374; sabre-wounds of the head, i. 427; sabre-cuts of the head and neck, and the infrequenpy of hernia cerebri, i. 428; amaurosis and inflamma- tion of the eye caused by the passage of a ball through or near the organ, i. 470; duration of syphilis under the non-mer- curial treatment, and subsequent occur- rence of secondary symptoms, ii. 103. Thomson, H., on the protraction of the period of incubation in hydrophobia, i. 404; case of amputation at the hip-joint, iii. 689. Throat, polypus of, iii. 477. Thumb, exarticulation of the metacarpal bone of, iii. 721. Thune on the causes of splay-foot, ii. 457; primitive and secondary valgus, ii. 457. Thyroid rupture, ii. 353. —----gland, inflammation of, iii. 385. ------artery, superior, ligature of, iii. 389. ------------inferior, ligature of, iii. 393. Tibia, fracture of, i. 636. Tibial ariery, anterior, aneurism of, ii. 543; ligature of, ii. 544; posterior, aneurism of, ii. 544; ligature of, ii. 544. Tiedkmann on the high bifurcation of the brachial artery, ii. 529. Tinea capitis and its varieties, ii. 60. Titley's, Dr., case of sarcomatous tumor of the scrotum, iii. 449. Todd, Dr., considers there is a difference between temporary and articular carti- lage, i. 250. Todd's case of a syphilitic child infecting its grandmother, i. 105. Toes, union of, ii. 509 ; supernumerary, in. 597; amputation of, iii. 686; exarticula- tion of, iii. 709. .,. Tongue, unnatural adherence of, in. &*$ enlargement of, iii. 382; cancer of, m. 520; removal of by ligature, in. 520; ex- tirpation of, iii. 521. Tooth-ache, ii. 134. Tonsils,inflammation of, quinsy:—symp- toms, i. 158; causes and terminations, i. 159; abscess, i. 159; Dr. Tweedie on enlargement of, i. 159; Guersent's cases of gangrene of, i. 159; treatment, ,.159; Drf W'atson on the local treatment, u 160; Hercy's inhaler, i. 160; scarifica- tions, i. 160; danger of wounding the carotid, or a branch, i. 160; Watson's cases, i. 160; South's recommendation of the actual cautery in case an arterial branch were wounded, i. 160; astringent gargles to be used on the subsidence of the inflammation, i. 160; opening the abscess with a guarded bistoury or the pharyngotome, i. 160; treatment after the pus has been evacuated, i. 160; in rare cases the abscess becomes external under the jaw, i. 160 ; Allan Burns on the spon- taneous bursting of the abscess, i. 161 ; attended with much danger, i. 161; de- tails of a case in which the trachea was deluged with purulent matter, and death by suffocation ensued, i. 161; Burns' advice in such cases to tap the abscess with trocar and canula, i. 161; in most cases of tonsillar abscess the action of emetics will cause its rupture; if not, it must be opened, i. 161; Burns' directions for opening a tonsillar abscess, i. 161; South's, i. 161; cases of fatal haemorrhage consecutive to opening a tonsillar ab- scess, mentioned by Portal, Allan Burns, Tyrrell, and Brodie, i. 162; Lawrence's case of alarming haemorrhage from punc- turing an immature tonsillar abscess, i. 162; hardening of the tonsils,!. 162; Else denies the existence of the so-called scirrhus ofthe throat,!. 162; Dr. Twee- die ascribes suoh cases to hypertrophy and induration alone, i. 162; roughness of the voice and deafness caused by en- larged tonsils, i. 162; South on the treat- ment of enlarged tonsils, i. 163; Allan Burns on the formation of calculi in the tonsils, i. 163; partial extirpation of en- larged tonsils, i. 163; description ofthe operation, i. 163; ligature ofthe tonsils* or the application of caustic not to be preferred to their removal by the knife, i. 164; various modes of effecting their removal by cutting, tearing out, tying, or by destroying with caustic, i. 164; the operation by cutting performed by Cel- sus, Richter, and Moscati, i. 164; that of tearing out the tonsils by Celsus and Fabricius ab Aquapendente, i. 164 ; tying the tonsils by Guillemeau, Sharp, Che- selden, Bibrach, Siebold, Bell, Cheva- lier, and Hard, i. 164; cauterizing the tonsils with red-hot iron or caustic by Severinus and Wieseman, i. 165; Else's objection to excision, especially in chil- dren, on account of the haemorrhage, i. 165; prefers Cheselden's operation, i. 165; Physick's guillotine instrument for amputating the tonsils, i. 165; Simpson's adaptation of Thorbern's sta- 926 ANALYTICAL INDEX. phylotome for the same operation, i. 165; the operation performed in the United States with scissors in prefer- ence to the knife, i. 165; Gibson's for- ceps, i. 165; South on this operation, i. 165; means of stopping the haemor- rhage,!. 166: Lawrence and Callaway on the haemorrhage following extirpation, i. 166; Shaw's case of extirpation follow- ed by superficial slough, alarming haemor- rhage, and ligature ofthe carotid, i. 166; relaxation of the uvula, i. 166; extirpa- tion ofthe uvula, i. 166; Bennati recom- mends cauterization with nitrate of silver, i. 167; Paulus iEgineta cauterizing it with the aid of the staphylokauston, i. 167; Pare used the ligature, i. 167; Ast- ley Cooper and South's opinion against the operation, i. 167. Torsion of arteries, i. 341. Tournel's case of dislocation ofthe scapu- lar end of the clavicle downwards, ii. 219. Toynbee on the synovial membrane, i. 236; non-vascularity of cartilage, i. 250; development of, i. 250; supply of nutri- ent fluid to articular cartilages, i. 250; vessels by which articular cartilages are nourished, i. 251; description of the canals in adult cartilage, i. 252; re- moval of the articular cartilage in old age, i. 268. Trachea, foreign bodies in, iii. 109, Tracheotomy, iii. 177, Transfusion, iii, 625. Travers on the cause of pain in inflamma- tion, i. 36; remarks that pain is not neces- sarily an attendant on inflammation, i.: 37; redness in inflammation, i. 37; in- crease of heat in inflammation, i. 37; experiments of Dr. John Thomson re- peated by, i. 40; oscillation attending the | recovery of the circulation in inflamma- tion, i. 41; effusion of serum, i. 45; lining membrane of an abscess, i. 49; i the circumstances which determine anj abscess to the surface, i. 49; purpose, which the formation of pus serves in the economy, i. 51; constitution of pus, i. 54;' process of ulceration, i. 64; objection to! the terms mortification and sphacelus, i.J 66; acute gangrene, i. 67; deep and ex- tensive effusions and injuries of nerves j causes of mortification, i. 68; chronic I gangrene, i, 72; severe phlebitis, i. 93; primary symptoms of gonorrhea, i. 176 ; gonorrheal sores, and their consequences, i. 187; secondary symptoms of gonor- rheal sores, i. 187; paronychia affecting the tendons, i. 216; the blood as a me- dium of organized adhesion in wounds, i, 320; formation of new vessels, i. 323; filling up a gaping wound, i. 324; case of wound of the posterior tibial artery, i. 338; traumatic tetanus, i 415 ; period of the accession of the disease after the re- ceipt of the injury, i. 415; causes of tetanus, i. 418; case of suicidal wound of the lingual or facial artery near its origin, with unsuccessful ligature of the common carotid, i. 474; effects of injury of the abdomen, i. 502; wounds of the abdomen, i. 503; case of wounded intes- tine, i, 507; wounds of the intestines communicating directly with the surface, i. 508 ; varieties of wounds of the intes- tines, i. 508; experiments on wounded intestine, i. 511; objections to returning a wounded intestine without suture into the abdomen, i. 514; withdrawal of the suture after union has taken place, i. 514; directions for stitching a wounded intes- tine, i. 514; reparation by artificial con- nexion of the divided parts of a wounded intestine, i. 516 ; treatment of wounded intestine, without feculent discharge or prolapse, i. 517 ; spontaneous reparation in wounded intestine, i. 517; effusion into the cavity of {he abdomen in cases of penetrating wounds, i. 518 ; impedi- ments to effusion of the intestinal con- tents in wounds of the bowels, i. 518; case in which he applied a ligature round the wound of a protruded stomach, i. 522; combined effects of mercury and syphilis in the production of the mercu- rial disease, ii. 109; cachexia mercurialis, ii. 110; nature of strangulation in rup- tures, ii. 269; effects produced by the ligature on the arterial coats, ii. 492; case of ligature of the carotid, ii. 508 ; treat- ment of branching aneurism, ii. 554; case of suppuration of the bursa of the knee-cap, iii. 181; treatment of hydrocele by puncture, iii. 224; case of impaction of calculus in the ureter, iii. 270; of se- condary haemorrhage after lithotomy, iii. 335 ; of calculus in the urethra, iii. 362; of stone broken up under the use of a constitutional stone-solvent, iii. 367 ; on the genus carcinoma, iii. 455; occasional inertness of scirrhus during life, iii. 509; resemblance of chimney-sweep's cancer to lupus, iii. 560; case of resection of the scapula, iii. 762; of resection ofthe cla- vicle, iii. 761. Travers', jun., case of dislocation into the ischiatic notch in a boy five years old, ii. 202; case of a foreign body in the wind- pipe for a long time, iii. 112. Trepanning, ) the operations of. See Trephining, ) Wounds ofthe Head. Treswart on the exhibition of prussic acid in tetanus, i. 419, ANALYTICAL INDEX. 927 Troccon's mode of operating in exarticu-1- lation of the four metacarpal bones, iii. 722. Troja on incipient production of new bone after necrosis, ii. 127. Trolliet considers the mucus from the inflamed mucous membrane ofthe bronchi in hydrophobia to be the vehicle of the poison, i. 401. Trousseau on tracheotomy in croup, iii. 115. Tubercle in bone, iii. 416. Tumours, adipose, iii. 426 ; encysted, iii. 429; atheromatous, iii. 433; sebaceous,iii. 434; sarcomatous, iii. 448; lardaceous, iii. 450. Tunaley's case of a bristle in the oesopha- gus, iii. 98. Turchetti's cases of malignant pustule, described by him as anthrax, i. 80. Tweedie, Dr. on enlargement of the ton- sils, i. 159; ascribes cases of the so-called scirrhus of the tonsils to hypertrophy and induration alone, i. 162. Tympanitis, iii. 218. Tyrrell's case of fatal haemorrhage con- secutive to opening a tonsillar abscess, i. 162; of protracted gleet, i. 195; distinc- tion between gonorrheal gleet, and gl eet from stricture, i. 195; diagnosis between inflammation and hysterical affections of the joints, i. 277; adhesive plaster, i. 361; case of wounded intestine, i. 507; of tre- panning the spine, i. 590; hydriodate of potash in general syphilis, ii. 101; case of compound dislocation of the sternal end ofthe clavicle backwards.ii. 218; of hook- foot, arising from an accident, ii. 461; of the existence of several aneurisms in the same person, ii. 477; of teleangiectasy treated by injecting a solution of alum, ii. 565; of a broken piece of catheter in the bladder, iii. 135; section of the prostate in the operation for stone, iii. 320; case of inhealing of a metallic frame to remedy a sunken nose, iii. 592; of excision of part of the hand, iii. 722; of necrosis of the lower jaw, iii. 745. Ulceration:—causes, i. 61; Hunter on ulcerative inflammation, i. 61; ulcerative j absorption, or absorption with suppura- tion, i. 63; progressive absorption, i. 63; Travers on the process of ulcera- tion, i. 64; ulceration of the synovial membrane, i. 339. _ Ulcers in general:—definition of, n. 41; causes, internal and external, n. 41 ?j division of ulcers into simple and com- plicated, ii. 41; subdivisions of compli- cated ulcers, ii. 41; reaction of ulcers on the organism, ii. 41; prognosis, n. 41 ;| treatment, ii. 42; three stages of the pro- gress of ulcers towards healing, ii. 42; symptoms and treatment of an inflamed ulcer, ii. 42; of the erethetic ulcer, ii. 43; of the torpid ulcer, ii. 43 ; symptoms, appearances, and treatment of the foul or gangrenous ulcer, ii. 43 ; Percy, La- barraque, Lisfranc, Lemaire, Ekl, Kli- matis, Biett, Cloquet, Cullerier, Boulay, and Pigne on the solution of the chlo- ride of lime in foul, gangrenous, and tor- pid ulcers, ii. 44; symptoms and treat- ment of .the callous ulcer, ii. 44 ; of the cedematous ulcer, ii. 44; of the fungous ulcer, ii. 44; of varicose ulcer, ii. 45; issues required if the ulcers are of long standing, ii. 46; atonic ulcers, ii. 46; causes, situation, and symptoms, ii. 46; prognosis, ii. 47; treatment, ii. 47 ; ap- plication of sticking-plaster, ii. 47 ; Un- derwood and Boyer allow the patient to walk while wearing the sticking-plaster, ii. 47; local application of aromatic and astringent remedies, ii. 47; Rust's treat- ment of chronic ulcers of the foot by the hunger-cure, ii. 48; South on the appli- cations of strips of plaster in the treat- ment of ulcers, ii. 48; general treatment, ii. 48; prevention of relapses, ii. 48; scorbutic ulcers, ii. 48; causes and symp- toms, ii. 49; characters, ii. 49; occa- sional causes of scurvy, ii. 49; Bateman on purpura haemorrhagic, or land scurvy, ii. 49; general and local treatment, ii. 50; scrofulous ulcers, ii. 50; causes, ii. 50; indications of the scrofulous dispo- sition, ii. 51; diseases dependant on scro- fula, ii. 51; characters of scrofulous sores, ii. 51; treatment of the sores must be constitutional, ii. 51; occasional dis- appearance of scrofula at puberty, or during the first pregnancy, ii. 51; gene- ral treatment of scrofula, ii. 51 ; local treatment of glandular swellings and scrofulous ulcers, ii. 52; local treatment of the ulcers when torpid, ii. 52; use of iodine and cod-liver oil, ii. 52; Lugol on iodine in scrofula, ii. 52; Lugol's formulae for the exhibition of iodine, ii. 52; exhi- bition of cod-liver oil, ii. 52; Negrier on fresh walnut leaves and their decoction in scrofula, ii. 53; Pollini's decoction, ii. 53; Russell and Burns on the treatment of scrofulous ulcers, ii. 53; South on the iodide of postassium and cod-liver oil in scrofula, ii. 53 ; scrofulous inflammation of the upper lip, nose, and cheeks, and its treatment, ii. 54; gouty ulcers, ii. 54; causes and characters, ii. 54; situation and diagnosis, ii. 54; the treatment of these ulcers, requires greatcare, for fearof metastasis, ii. 55; general treatment, ii. 928 ANALYTICAL INDEX. 55; wine of colchicum seeds the most efficacious remedy in gouty and rheumatic affections, ii. 55; Lewin's experiments on colchicum as a cause of an increased production of uric acid in the urine, ii. 55; local treatment, ii. 55 ; earthy mat- ters deposited in gout, ii. 55 ; impeti- ginous ulcers, ii. 56; varieties, ii. 56 ; to be considered as symptoms of chronic eruption of the skin, ii. 56; causes of chronic eruptions, ii. 56; subdivisons of impetiginous ulcers, ii. 56; treatment, general and local, ii. 56; herpetic ulcers, ii. 57; characters, ii. 57; varieties of herpes, ii. 57 ; characters of herpes exe- dens or lupus, ii. 58; proximate cause, ii. 58 ; hereditary disposition to herpes, ii. 58 ; remote causes, ii. 58; complications with scrofula, syphilis and gout, ii. 58; danger of the repulsion or imperfect development of herpes, ii. 58; Veiel's division of herpes, ii. 58; treatment of herpetic ulcers, ii. 59; anti-herpetic medicines, ii. 59; external treatment, ii. 59; scalled head or tinea capitis, ii. 60; symptoms and characters of scalled head, ii. 60; characters of tinea favosa, ii. 60; of tinea granulata, ii. 61; of tinea fur- furacea, ii. 61; of tinea asbestina, ii. 61; of tinea muciflua, ii. 61; consequences of long-cpntinued scalled head, ii. 61 ; proximate and occasional causes, ii. 61; sudden suppression of sealled head some-j times dangerous, ii. 62; treatment, ii. j 62; local treatment, ii. 62; milk crust or crusla lactea, ii. 62; characters, ii. 62; of crusta serpiginosa, ii. 63 ; causes of crusta lactea, ii. 63; crusta serpiginosa always consequent on complication of crusta lactea with syphilis or herpes, ii. 63 ; Autenrieth's opinion that crusta serpiginosa is connected with itch, ii. 63; local and general treatment of crusta lactea, ii. 63; of crusta serpi- ginosa, ii. 63; von Wedekind on the treatment of crusta lactea, ii. 63; itch, scabies or psora, ii. 64; characters, ii. 64; characters and causes of itch ulcers, ii. 64; Krause on the existence of itch without eruption, ii. 64; cause of itch, ii. 64; the itch-mite, ii. 65; symptoms of scabies spuria, ii. 65; Wichmann, Bateman, Baker, Canton, Alibert, Lugol, Renucci, Albin Gras, and Eble on the ex- istence of the itch-mite or acarus scabiei, ii. 65; Eble's observations on the acarus, | ii. 65; Emery and Aube on the contagion of itch, dependent on the itch-mite, ii. 65, 66; the inoculation of itch by trans- planting the acarus, ii. 66; Mouffet, Avenzoar, Joubert, Linnaeus, Dr. Adams, and Hyacinth Cestoni on the acarus sca- biei, ii. 66; Gale's experiment with the itch-mite, ii. 66; consequences of neglect- ed itch, ii. 66 ; simple and complicated itch, ii. 66; treatment of simple itch, ii. 66; objections to greasy applications in the treatment of itch, ii. 67; Horn's lini- ment, ii. 67; Fischer on the applica- tion of smear, black, or green soap, ii. 67; mode of using it, ii. 67; symptoms, which occur during this treatment, ii. 68 ; treatmeht of itch by Graf, Vezin, and Pentzlin, ii. 68 ; treatment of itch by liquid sulphuret of Jime in the Bel- gian army, ii. 69; treatment of com- plicated itch, ii. 69; of itch-ulcers, ii. 69; of suppressed itch, ii. 70; venereal ulcers, ii. 70; distinguished as primary and secondary, ii. 70; causes, ii. 70; South on the inappropriate use of the terms "venereal ulcer," and "chancre" as synonymous, ii. 71; John Hunter on the two modes in which the venereal poison affects the system, ii. 71; Law- rence on the progress of syphilis from one part of the body to another, ii. 71; the operation of the venereal contagion requires a peculiar delicate structure of the part affected, or a deprivation of its cuticle, ii. 71; symptoms of chancre, ii. 71; characters of the pus secreted by venereal ulcers, ii. 72; John Hunter and Ricord on the period at which chancres appear after infection, ii. 72; John Hunter on the symptoms of chancre, ii. 72 ; Lawrence on the progress of ulcera- tion in a syphilitic sore, ii. 72; Lawrence on the Ave kinds of syphilitic sores, ii. 73; the pus of the ulcer the special vehicle of the venereal contagion, ii. 73 ; Hunter's experiments by inoculating with the matter of gonorrhea and chancre, ii. 73 ; Ricord on inoculation for the pur- pose of distinguishing syphilitic sores, whether primary or secondary, ii. 74; buboes the first symptoms of general syphilis, ii. 75; may be idiopathic, or sympathetic, ii. 75; symptoms, progress, and terminations, ii. 75; John Hunter on the true venereal buboes, ii. 75 ; Ricord on the seven kinds of buboes, ii. 75; Hunter and Ricord on the existence of syphilitic buboes, without primary sore, ii. 76; general syphilis attacks specially either the skin, mucous membranes, or bones, ii. 77; John Hunter on the con- tinuance of the constitutional irritation from lues, independent of continued ab- sorption, ii. 77; inflammation of the mu- cous membrane of the throat, ii. 77; symptoms, appearances, and results, ii. 78; venereal eruptions, ii. 78 ; symp- toms, ii. 78; Lawrence on the four kinds ANALYTICAL INDEX. 929 of syphilitic eruptions, ii. 78; herpetic eruptions, rhagades, veruccae, and con- dylomata, ii. 79; John Hunter and Ricord on the non-infectious character of the pus from a secondary syphilitic sore, ii.79, 80; symptoms and results of syphilis in the bones, ii. 80; modifications of the symp- toms of syphilis, ii. 81; primary syphi- litic ulcers no decided external character, ii. 81; Abernethy on pseudo-syphilis, ii. 81; Abernethy on the means of dis- tinguishing between true and false syphi- lis, ii. 82; Carmichael's objections to the terms syphilis, syphiloidal, and pseudo- syphilis, ii. 82; Carmichael bases his arrangement of venereal complaints on the character of the eruption, ii. 82 ; Ricord on the causes of the varied ap- pearances of chancre or primary syphi- litic sore, ii. 82; differences in secon- dary syphilis, ii. 84; prognosis, ii. 85 ; John Hunter on the relative rapidity of cure of gonorrhea, chancre, and lues ve- nerea, ii. 85; Abernethy on the occa- sional spontaneous healing of chancre, ii. 85; John Hunter on the relapse of ulcers after chancres have cicatrized, ii. 85; treatment of syphilis with mercury, ii, 86; in treating chancre, an especial indication to prevent general syphilis, ii. 86 ; local treatment, iL 86; Ricord on the destruc- tion of the ulcer by the nitrate of silver, ii. 86 ; internal exhibition of mercury, ii. 86; Lawrence on the exhibition of mer- cury in cases of chancre, and on the rarity of the occurrence of secondary symptoms when mercury has been used, ii. 86 ; Lawrence on the extent to which the use of mercury may be pushed, ii. 87 ; Green on the use of mercury in syphilis, and on the forms in which it should be employed, ii. 87 ; circumstances requiring the local exhibition of corrosive sublimate, ii. 88; Delpech on frictions with the ung. hyd. cin. in primary syphilis, ii. 89; South on the treatment of sloughing chancre, ii. 89 ; mercury not to be used either inter- nally or externally under such circum-j stances, ii. 89; mercury should be ex-i hibited for some time in smaller doses after the chancre has cicatrized, ii. 89; treatment of buboes, ii. 89; tendency of idiopathic buboes to suppurate, ii. 90 ; treatment of the remaining ulcer, ii. 90; | treatment of the indurated bubo, ii. 90 ;j mode of opening suppurating buboes, n.j 90; Ferguson, Fricke, Reynaud, and Ricord on the treatment of buboes, ii. 90 ; South on the treatment of suppurating bubo, and of the subsequent ulcer, ii. 90; treatment of general syphilis by mercury, ii. 91; external employment of mercury, i when required, ii. 91; sublimate baths, ii. 91; the internal exhibition of mercury preferable in ordinary syphilis, ii. 91 ; local symptoms require special treatment, ii. 91 ; Rust's treatment of syphilitic ulceration of the throat and palate, ii. 91 ; treatment of syphilitic eruptions, ii. 92 ; treatment of the granulations by caustic or the knife, ii. 92 ; of syphilitic disease of the bones, ii. 92; mercurial fumiga- tion in syphilitic ulceration of the tonsils and pharynx, ii. 92 ; South on secondary syphilitic sores and their treatment, ii. 92 ; South on the treatment of nodes, ii. 93; necessary to vary the mercurial preparations in use according to consti- tution and other circumstances, ii. 93 ; Starke on the phosphor, hydrarg., von Graefe on the iodide and bromide of mer- cury, and Mendaga and Parent on the hydrarg. cyan., ii. 93; salivation not necessary for the cure of the venereal disease, ii. 94 ; treatment of salivation, ii. 94 ; treatment of old cases of venereal disease, ii. 94 ; Louvrierand Rust on the friction-cure, ii. 94 ; cases in which the friction-cure is indicated, ii. 95 ; cases in which it is contra-indicated, ii. 95 ; South on the friction-cure, ii. 95; mode of em- ploying it, ii. 95; Wedemeyer, Rust, and South on the number of times the frictions may require to be practised, ii. 96; the order in which the rubbings-in are to be conducted, ii. 96; symptoms which occur during this treatment, ii. 97 ; the Montpellier modification of the friction-cure condemned, ii. 97; treat- ment to be adopted, if the salivation or critical sweating b§ suddenly suspended, ii. 97; occurrence of spasmodic or ner- vous symptoms, ii. 97 ; subsequent treat- ment, ii. 97 ; Weinhold's mercurial cure, ii. 97; mode of employing it, ii. 98; Zittmann's decoction, ii. 98; mode of exhibiting it, ii. 98 ; formula for Zitt- mann's decoction, ii. 98; the Arabian treatment, ii. 99; Dzondi's treatment, ii. 99; the preference given to the use of Zittmann's decoction, ii. 100; treatment of syphilis without mercury, ii. 100; va- rious modes of treating secondary symp- toms without mercury, ii. 100 ; Pitcairn, Chrestien, and Niel on gold and its pre- parations in primary and secondary sy- philis, ii. 101; Ricord, Eusebe de Salle, Lallemand, Biett, Paillaud, Wallace, Dr. Williams, Judd, Tyrrell, Ebers, von Has- selberg, and Hacker on iodine and hy- riodate of potash in gonorrhea and general syphilis, ii. 101; Forster on the cure of syphilis by the chloride of gold and soda, ii. 102; treatment of syphilis without 930 ANALYTICAL INDEX. mercury in England, ii. 102 ; Hill, Hen- nen, Rose, Guthrie,and Thomson on the duration of the disease under this treat- ment, and on the subsequent occurrence of secondary symptoms, ii. 103; South on the proper mode of exhibiting mercury in the treatment of syphilis, ii. 103 ; objec- tions to the treatment without and with mercury, ii. 103; syphilis in infants, ii. 104; causes of infection, ii. 104 ; Evan- son and Maunsell on the communica- tion of syphilis to the foetus in the womb,ii. 104 ; Huguier on the period at which syphilis shows itself after birth, ii. 104; infection of the child by a syphi- litic nurse, ii. 105; Dyckman's assertion that the child may be infected by the milk of a diseased nurse, ii. 105 ; Hunter, Lawrence, and Todd's cases of diseased children infecting the nurses, ii. 105; Colles doubts whether the child can infect the nurse, unless she have ulceration of the nipple,ii. 105; Evansonand Maunsell on the symptoms of syphilis in infants, ii. 106; Lawrence on syphilitic iritis, and ulceration about the anus in infants, ii. 106; prognosis, ii. 106; Evanson and Maunsell on the treatment of syphilis in infants, ii. 106; Swediaurand Bacot ob- ject to the use of corrosive sublimate in such cases, ii.106; Hey, Lawrence, Hun- ter, Ricord, and South on the possibility of infection from secondary syphilis, ii. 106. Ulna, fracture of, i. 612; dislocation of, ii. 229. Ulnar artery, ligature of, ii. 530. Ullsamer on endemic prolapse ofthe womb from the use of the labour-chair, ii. 375. Umbilical rupture, ii. 343. Underwood on the treatment of ulcers by sticking-plaster, ii. 48. Urban's opinion that there is a circlet of small vesicles round the wound or scar in hydrophobia, i. 405. Ureter, stone in the, iii. 269. Urethra,Inflammation of:—Gonorrhea; causes, i. 174; symptoms and progress, i. 175; chordee, i. 175; balanitis, i. 176; phymosis, i. 176; paraphymosis, i. 176; Hunter and Astley Cooper on the period when gonorrhea first shows itself after infection, i. 176; Astley Cooper, Hunter, and Travers on the primary symptoms, i. 176; Hunter on the specific extent of the inflammation, i. 176; Hunter and Astley Cooper on the actual seat of the discharge, i. 177; Cooper on the post- mortem appearances, i 177; Hunter on the small swellings which are noticed ex- ternally near the urethra, i. 177; Hunter on the size and form of the stream of urine, 177; Hunter and Cooper on the occurrence of haemorrhage in severe go- norrhea, i. 177; in rare cases the corpus spongiosum is ruptured, i. 178; Macmur- do's case of rupture of a vessel in the penis during coition, i. 178; Hunter on inflammatory and spasmodic chordee, i. 178; Abernethy on permanent chordee from the inflammation having extended to the corpus spongiosum, i. 178; Hunter on the extent of local irritation, i. 178; South on retention of urine in severe gonorrhea, i. 178; Hunter on the exten- sion of the inflammation to the bladder, and the consequent inability of that viscus to retain its contents, i. 178; the consti- tution rarely primarily affected, i. 179; Hunter's case of fever preceding gonor- rhea, i. 179; continuance of the symp- toms, i. 179; gleet, i. 179; Astley Cooper on the influence of constitutional causes on gonorrhea, i. 179; consequences of gonorrhea, i. 179 ; seat of, in the female, i. 179; its propagation to the rectum, i. 180; distinguishing characters from leu- eorrhea, i. 180; Ricord on acute urethritis in the female, i. 180; Ricord on utero- vaginal gonorrhea, i. 180; Hunter on the extension of the inflammation to the bladder in the female, i. 180; doubts its extension to the ovaries, i. 180; Ricord regards ovaritis as a complication of go- norrhea, i. 180; swelling and infiltration of the external parts, considered by Ri- cord a kind of phymosis or paraphymosis, i.180; abscesses in the labia or nymphae, i. 180; Hunter and Ricord on abscesses complicating gonorrhea, i. 180; distinc- tion between gonorrhea and leucorrhea not easy, i. 180; Dr. Locock on leucor- rhea, i. 180 ; characters of the secretion, i. 180; Locock and Jewel on the distin- guishing signs between leucorrhea and gonorrhea, i. 181; pudendal discharges in female infants, i. 181; Locock on the pudendal discharges during dentition, i. 181; Dr. Percival, Dr. Ferriar, Dr. Mack- intosh, Kinder Wood, and Capuron on an epidemic vaginal catarrh, i. 182; varieties of gonorrhea, i. 182; Lawrence's divi- sion into gonorrhea benigna and gonor- rhea virulenta, i. 182 ; Hunter oh gonor- rhea from simple causes, i. 182; Sir Fverard Home on the internal use of ar- senic and ginger as a cause of gonorrhea, i. 182; simple gonorrhea originating in leucorrhea in the female, i. 182; Hun- ter's case, i. 182; South on gonorrhea virulenta a constitutional disease in cer- tain persons, i. 183; Lawrence's opinion, i. 183; Abernethy on gonorrhea viru- ANALYTICAL INDEX. 931 lenta, i. 183; question of identity be- tween gonorrhea and syphilis, i. 183; ob- servations and experiments of Hernandez and Ricord, i. 183; Becket's memoran- dum respecting gonorrhea, i. 183; John of Gatesden's Rosa Anglicana, i. 183; John of Arden mentions the chaudi- pisse, i. 184 ; the supposed origin of sy- philis on the discovery of America, or at the siege of Naples, i. 184; South's opinion that syphilis was known to John of Arden, and perhaps to John of Gates- den, i. 184; Hunter on the identity of the two poisons, i. 184; accounts for the two different effects of the same poison, by the gonorrhea preceding from a secre- ting surface, while the chancre is formed on a non-secreting surface, i. 184 ; South on the frequency of the co-occur- rence of chancre and gonorrhea, i. 184 ; Bell denies the identity of gonorrhea and syphilis, i. 185; Hernandez's expe- riments on the subject, i. 185 ; the ulcers produced by inoculating with gonorrheal virus are not syphilitic, i. 186; Ricord's observations and experiments, i. 186; Ricord's inferences from the results, of the inoculation with gonorrheal matter, i. 186; the opinion that gonorrhea is un- attended by ulceration contraverted by Ricord, i. 186; Travers on gonorrheal sores and their consequences, i. 187; Travers on the secondary symptoms of the gonorrheal sore, i. 187; South on the gonorrheal sore throat, i. 188; diagnosis of the several kinds of gonorrhea, i, 188; the swelling of the testicle, and of the inguinal glands and prostate, sympa- thetic not syphilitic, i. 188; Hunter on the sympathetic swellings in gonorrhea, i. 188; Cooper on the sympathetic bubo of gonorrhea, i. 188; in all suspicious cases of discharge from the male or fe- male genitals, if the disease be syphilitic, the speculum will show it in the female, and inoculation with the matter will indi- cate it in the male, i. 189; Ricord on the examination of public prostitutes, i. 189; treatment, 189 ; Hunter on the duration and spontaneous cure of gonorrhea, i. 190; treatment, i. 190; employment of stimulating injections, i. 190; John of Arden's prescription, i. 190; Beckett's prescription, i. 190; Abernethy's objec- tion to any attempt to check gonorrhea, i. 191; recommends a soothing practice, i. 191; South's treatment, i. 191; Carmi- chael's injection of a strong solution of nitrate of silver, i. 191; Ricord's treat- ment by the direct application of the nitrate of silver, i. 191; Astley Cooper s treatment, i. 191 ; observes that gonor- rhea is difficult to cure in strumous sub- jects, i. 192; treatment of hordee, i. 192; means to check haemorrhage, if it occur, i. 192; South's treatment of pain- ful erections and chordee, i. 192; Astley Cooper, Ricord, and Hunter on the reme- dies for chordee, i. 192 ; South, Hunter, and Ricord on the treatment and arrest of haemorrhage from the urethra, i. 192 ; subsequent treatment of gonorrhea, i. 193 ; treatment of the syphilitic form of gonorrhea, i. 193; treatment of gonor- rhea in women, i. 193; South and Ricord on its treatment in women, i. 193; use of stimulating injections in some cases objectionable, i. 193; Home's cases in which the use of stimulating injections caused the sides of the vagina to unite together by the adhesive inflammation, i. 193; Ricord's treatment of severe cases by the introduction of a plug of lint dip- ped in an emollient narcotic liquid, i. 193; his treatment of obstinate cases by filling the vagina with dry lint, i. 193; ulcerations and papulous granulations to be cauterized, i. 193; Ricord on ulce- rations of the mucous membrane of the womb, i. 193; vegetations in the interior of the urethra to be destroyed by incision or cauterization, i. 194; Ricord on gonor- rhea in the female urethra, i. 194; treat- ment of gleet, i. 191; South and Astley Cooper on gleet, i. 194 ; Astley Cooper, Hunter and South on the infectious na- ture of gleet, i. 194; Tyrrell's case of protracted gleet, i. 195; Tyrrell on the distinction between gonorrheal gleet, and gleet from stricture, i. 195; Astley Cooper on the distinction between gonor- rhea and gleet, and abscess of the la- cunae, i. 195 ; Astley Cooper on the treat- ment of gleet, i. 195; constitutional treat- ment, i. 195; Ricord on inoculation with gonorrhea to cure gleet, i. 195; South's condemnation of that practice, i. 196; use of cubebs, i. 196; Delpech's condemnation of cubebs, i. 196; symp- toms produced by the exhibition of cu- bebs, i. 196; Delpech has shown that cubebs do not cause inflammation of the testicles, i. 197; Delpech's treatment of gonorrhea, i. 197; Velpeau, Michaelis, Richon, and De Salle on the treatment of gonorrhea, i. 197; Astley Cooper on the use of cubebs in gonorrhea, i. 197 ; South on cubebs and copaiba in gonorrhea, i. 198; external gonorrhea, balanitis, i. 198; causes and symptoms, i. 198; Hun- ter and South on balanitis, i. 198; treat- ment, i. 198; Ricord and South on the treatment, i. 199 ; gonorrhea ofthe nose, i. 199; Benjamin Bell's cases, i. 199; 932 ANALYTICAL INDEX. treatment of gonorrhea, dependent on a gouty or herpetic disease, i. 199. Urethra, rupture of, i. 535. See Wounds ofthe Penis. Urethra, Stricture of, iii. 63; stricture of the urethra of more frequent occur- rence than in any other outlet, iii. 63; symptoms, iii. 63; Brodie on incon- tinence of urine in stricture, iii. 64; extravasation of urine from rupture or sloughing of the urethra behind the stric- ture, iii. 64; Brodie on extravasation of urine from ruptured urethra in stricture, iii. 64; Brodie on abscesses communi- cating with the bladder in old cases of, stricture, iii. 64; changes in the urethra in old strictures, and the attendant symp- toms, iii 64; Brodie on the complication of stricture with enlarged prostate, iii. j 65; Brodie's case of enlargement of the urethra from stricture, iii, 65; Brodie on the formation of cysts of the urethral mu- cous membrane in stricture, iii. 65; Bro- die on the occurrence of rigors and fever; in cases of stricture, iii. 66; causes of stricture, iii. 66 ; Brodie on the existence! in old strictures of an indurated mass1 at the lower portion of the penis, iii. 66; seat and characters of stricture, iii. 67; Hunter's description of three forms of stricture, iii. 67; Brodie on the original! seat of stricture, iii. 68; diseases liable) to be confounded with stricture, iii. 68; diagnosis, iii. 68; prognosis, iii. 68; treatment, iii. 69; mode of determining the seat of the stricture, iii. 69; Brodie on the use of a full-sized bougie on de- termining the seat of the stricture, iii. 70; preparation of common bougies, iii. 70; Astley Cooper, Abernethy and Bro- die on passing the bougie, iii. 73; Astley Cooper and Abernethy on the use of metallic bougies, iii. 73; Brodie on the treatment of stricture with bougies, and on their applicability to the respec- tive kinds of stricture, ii. 74; Brodie's directions for the introduction of the1 bougie, iii. 74; South on the danger of i using plaster bougies, iii. 74; South onj the introduction of the bougie, iii. 74; South on the general treatment of stric- ture, iii. 75 ; the time the bougie should ' be left in the urethra, and ihe frequency of its introduction, iii. 75 ; precautions to be taken when the instrument is left in the urethra, iii. 76; gradual increase in the size of the instrument used, iii. 76; Arnott's oil-silk tube, iii. 76; action of the bougie, iii. 77; symptoms occasion- ally produced by it, iii. 77; Astley Cooper and Abernethy on haemorrhage from the urethra after passing the bougie, iii. 77; Astley Cooper and South on the practice to be adopted when a laceration of the urethra by the bougie is suspected, iii. 77; destruction of the stricture by caustic, iii. 78; by ulceration to be rejected as dangerous, iii. 78; Brodie on the destruc- tion of stricture by ulceration, iii. 78; cauterizing a stricture from before back- wards, iii. 78; preparation of armed bougies, iii. 78; Hunter, Home, and Whately on the use of the armed bougie, iii. 79; objections to this mode of cauteri- zation, iii. 79; cauterizing the walls of the stricture, iii. 79; Whately and Arnott on cauterizing the walls of the stricture, iii. 79; use of bougies armed with caus- tic potash, iii. 80; Whately and Lawrence on the use of bougies armed with caustic potash, iii. 80; Ducamp's mode of cauterizing the urethra, iii. 81; subse- quent treatment, iii. 81; Ducamp's mode of dilating the urethra after cauterization, iii. 81 ; Ducamp's caution respecting the use of caustic, iii. 82; Lallemand, Sega- bas, and Tanchou's causlic-holders, iii. 83 ; relative advantages of the treatment by bougies and by caustic, iii. 83; Ast- ley Cooper, Brodie, Lawrence and South on the use of the armed bougie, iii. 84; cutting into the stricture, and subsequent dilatation, iii. 85; Jameson's treatment of stricture, iii. 85 ; formation of false passages, iii. 86; treatment, iii. 86; South on the treatment of false passages, iii. 86; congenital closure of the urethra. iii. 86; treatment, iii. 86. Urethra, calculus in the, iii. 363. Urinary fistula, ii. 174. Urine, retention of, iii. 125. Urethroplasty, ii. 179. Uvula, relaxation of, i. 166; extirpation of, i. 167. Vaccination or inoculation with cow pock, iii. 621 ; definition, iii. 621 ; use of the lymph, iii. 622; Dr. Gregory on the origin of vaccination, iii. 622 ; Dr. Jen- ner's discovery, iii. 622; Cline, the first experimenter, iii. 622; Dr. Gregory on the preservation of vaccine lymph for transmission, iii. 622 ; Gregory on the pe- riod at which lymph should be taken for vaccination, iii. 623 ; vaccination an ope- ration without danger, iii. 623 ; mode of vaccinating from a fresh pustule, iii. 623 ; Dr. Gregory on the operation of vacci- nation, iii. 623 ; vaccination with dry matter, iii. 623 ; appearances after effec- tual vaccination, iii. 623 ; Gregory on the appearances after effectual vaccination, iii. 624; irregularities in the course of the vaccine vesicle, iii. 624; Gregory ANALYTICAL INDEX. 933 on the insusceptibility of some consti- tutions to the vaccine virus, iii. 624; after-treatment, iii. 625 ; Gregory on the appearance of vaccine lichen, iii. 625. Vagina, wounds of, i. 533; prolapse of, ii. 389 ; closure, and narrowing of, iii. 87; polypus of, iii. 494. Vaginal rupture, ii. 353. Valentin on the exudation-corpuscles, i. 45 ; microscopic characters of pus, i. 46; microscopic results of suppuration, i. 49; mode of amputating by the circular in- cision, iii. 640. Valgus, ii. 456. Valsalva on the lengthening of the limb in hip-disease, i. 285. Varicose aneurism, ii. 549. Varix, aneurismal, ii. 546. Varices:—definition, ii. 567; characters, ii. 567; Brodie on the effects of inflam- mation on the blood in veins,' ii. 568; Hodgson and Petit on the coagula in vari- cose veins, ii. 568 ; causes, ii. 568; Dr. Baillie's case of obliterated vena cava in- ferior, ii. 569 ; Brodie's case of varicose veins ofthe fore-arm, ii. 569 ; Cline'scase of obliteration of the inferior vena cava, ii. 569; Brodie's cases of varicose veins ofthe arm and chest from compression of the subclavian veins, ii. 569 ; Petit and Velpeau's cases of varices in the upper extremities, ii. 570; South and Cline's eases of varix of the deep-seated veins, ii 570; treatment, ii. 570; Brodie on the application of adhesive plasters in the treatment, ii. 570 ; radical cure, ii. 571 ; Gottschalk on the treatment of varix, ii. 571; puncture with a lancet, ii. 571; in- cision, ii. 571; extirpation, ii. 571; ap- plication of the ligature, ii. 572; Ricord on the application of the ligature, ii. 572; Sir E. Home and South on the ligature of the saphena for varix, ii. 572; Solera's operation by cutting through the vein above and below, ii. 572; Brodie on the subcutaneous division of the vein, ii. 572; application of the actual or potential cautery, ii. 573; Bonnet, von Froriep, Mayo, and Brodie on the application of caustic, ii. 573; introduction of needles through the walls of a vein, ii. 573 ; modes of operating, ii. 573; Velpeau on the introduction of needles, ii. 574 ^la- teral compression of the vein, ii. 574; occasional consequences of operations on varicose veins, ii. 575; varicocele or cirsocele, ii. 575; definition and charac- ters ofthe disease, ii. 575; Breschet and South on spermatocele, ii. 575 ; causes of, ii. 575; Morgagni, Astley Cooper and Lenoir on the causes of, ii. 577; Vol iii.—79 consequences, ii. 577; treatment, ii. 577; operations for the radical cure, ii. 577; Charles Bell and Delpech on the ligature of the spermatic veins, ii. 578; Maunoir on the ligature of the spermatic artery, ii. 578; Fricke, Kuh, Davat, Franc, Ray- naud, Wormald, A. Cooper, Lehmann, and Breschet's operations, ii. 578; esti- mate ofthe relative value of these opera- tions, ii. 579; mode of performing Bres- chet's operation, ii. 579; after-treatment, ii. 580; haemorrhoids or piles, ii. 581; definition and varieties, ii. 581; situation and consequences, ii. 581; Bushe on the local symptoms of piles, ii. 582; Bushe on the effects of the loss of blood from piles, ii. 582 ; causes, ii. 582; treatment, ii. 582; extirpation, ii. 583 ; Rousseau and Delpech's mode of extir- pating piles, ii. 583,584; Copeland, Bro- die, Bushe, and Syme on the removal of internal piles by ligature, ii. 584; Petit, Kirby, and Brodie's cases in which se- vere symptoms followed the use of the ligature for piles, ii. 584; Copeland and Brodie on the application of the ligature, ii. 584 ; extirpation of degene- rated piles, ii. 585; consecutive haemor- rhage, symptoms and treatment, ii. 585; Bushe on the treatment ofthe consecutive haemorrhage, ii. 585; Cline, Cooper, and Brodie on excision of piles, ii. 586. Varus, ii. 445. Veiel's division of herpes, ii. 58. Veitch's mode of amputating at the hip- joint by the circular cut, iii. 689. Velpeau's treatmentof erysipelas by mode- rate compression, i. 125; on pressure in the treatment of burns, i. 134 ; considers it best adapted to cases of burn in the third and fourth degrees, but also appli- cable to those ofthe second, i. 135: mode of applying compression, i. 135; advan- tages of this plan of treatment, i. 135 ; treatment of gonorrhea, i. 197; of com- plete anchylosis, i. 275; on the three ope- rations for the relief of bony anchylosis, i. 275; consequences of the adhesion ofthe knee-pan to the condyles ofthe femur, i. 275; objections to the use of Louvrier's apparatus, i. 276; torsion of arteries, i. 276; treatment of artificial anus connected with the caecum, ii. 161; case of simple dislocation of the sternal end of the cla- vicle inwards and backwards, ii. 218; primitive direction of dislocation of the humerus, ii. 221; operation for prolapsus uteri, ii. 379; modification of Hey's opt- ration for prolapse of the rectum, ii. 40c; acupuncture of the artery in aneurism, ii. 503; ligature of the external maxillary 934 ANALYTICAL INDEX. or facial, ii. 514; case of varix in the upper extremity, ii. 570; introduction of needles in the treatment of varix, ii. 574; injections of iodine in hydrarthrus, iii. 183; hydrocele caused by gonorrhea, iii. 222; mode of amputating at the knee with the circular cut, iii. 700; at the ankle-joint, iii. 700; mode of operating in exarticulation of the fore-arm at the elbow, iii. 719; operation in excision ofthe wrist, iii. 735. Venesection, iii. 608. Ventral rupture, ii. 348. Verdier's artery-compressor, i. 331. Vering's objection to the union of pene- trating wound ofthe chest, i. 493. Vermandois on the lengthening of the limb in hip-disease, i. 285; excision of the carious head of the femur in hip-disease, i. 300; experiments on the excision of joints, iii. 727. Vertebral artery, ligature of, ii. 526. Vertebrae, fractures and dislocations of, i. 582; dislocations of, ii. 111. Vesico-vaginal fistula, ii. 188. Vezin on the treatment of itch, ii. 68. Viborg on the treatment of salivary fistula, ii. 147. Vidal's proposal to occlude the vulva in complete destruction of the vagina and wall of the bladder, ii. 197; surgical treat- ment of dislocation of the thumb from the metacarpal bone, ii. 235; cause of the difficulty experienced in reducing this dislocation, ii. 235 ; operation for the di- vision ofthe inner fold of the prepuce, iii. 58. Vigaroux's case of excision of a joint, iii. 726. Vignolo on simultaneous dislocation of the radius forwards, and of the ulna back- wards, ii. 232. Viguerin's mode of treating congenital hy- drocele, iii. 231. Villaume on dislocation of the upper end ofthe radius forwards, ii. 231. Villerme on the reunion of fractures, i. 548 ; double formation of bony substance in fracture, i. 549; production of callus, i. 549. Vincent's fatal case of viper-bite, i. 389; case of calculi in the perineum, iii. 365; of calculi between the prepuce and glans penis, iii. 366. Voelter on the use of the suture in vesico- vaginal fistula, ii. 190. Vogel on the phenomena of inflammation under the microscope, i. 41; formation of pus, i. 46; effects of the resorption of pus, i. 48; noma, i. 75 ; essential element of medullary fungns, iii. 460; blood-fun- gus, iii. 460. Vohler's mode of amputating at the hip- joint with two flaps, iii. 696. Voillemier's case of dislocation of the wrist, ii. 233; diagnostic signs of disloca- tion of the wrist, and fracture of the lower end ofthe radius, ii. 233. Volpi has not found benefit from the actual cautery, when the first symptoms of hip- disease occurred at the knee and not at the hip, i. 294 ; case of reduction of the consecutive dislocation in hip-disease, i. 297; apparatus for fracture of the neck of the femur, i. 624. Wachter's experiments on the excision of joints, iii. 727. Wagner's Dr., cases of malignant pustule, produced by contact and by eating the flesh of diseased animals, i. 80. Wallace, Dr., on hydriodate of potash in syphilis, iii. 201. Wallner's treatment of fracture of the lower jaw, i. 580. Walshe, Dr., on the genus carcinoma, iii. 455. Walther's, von, plan of opening a cold abscess with a seton, i. 105; treatment of fistulous passages, i. 108; seat of boils originally in the sebaceous glands of the skin, i. 150; incisions in carbuncle, i. 155; after-management of ligatures on arteries, i. 338; symptoms of laceration of the brain, i. 451; employs trepanning in injuries of the head only when secondary symptoms of irritation and pressure require it, i. 454; objection to dressing the wound after the operation for rectal fistula, ii. 167; simultaneous dislocation of both inferior oblique pro- cesses of one of the cervical vertebrae, ii. 212; nature of strangulation in ruptures, ii. 269; incision of the hernial sac, and the introduction of lint-tents for its radi- cal cure, ii. 283; formation of urinary calculi, iii. 237; origin of oxalic acid in the urine, iii. 244; fungus of the dura mater, iii. 420; objections to operating for fungus of the dura mater, iii. 424; dif- ference between fungus haematodes and sarcoma medullare, iii. 459; ligature of the spermatic artery in sarcocele, iii. 555; case of excision of the cervix uteri pre- ceded by excising the pubic arch, iii. 567; management of the periosteum in amputations, iii. 642; mode of ampu- tating at the hip-joint with two flaps, iii. 692; mode of operating in partial ampu- tation of the foot preferred, iii. 705; in am, ul.i tion at the shoulder-joint by an ANALYTICAL INDEX. 935 upper and an under flap, iii. 712; in ex- articulation of both middle met acarpal bones, iii. 722; case of excision of part of the hand, iii. 722; mode of operating in resection of the scapula, iii. 762. Wantzel on the causes of club-foot, ii. 446. Ward's, Dr., application of flour in the treatment of burns, i. 132; mode of appli- cation, i. 132 ; objection to liquid appli- cations, i. 132; modus operandi of the flour, i. 133. Wardenburg's apparatus for fractures of the olecranon, i. 614. Wardrop on ingrowing ofthe nail, i. 222; on onychia maligna, i. 226; evulsion of the nail in the treatment of that disease, i. 227; internal treatment in onychia maligna, i. 227; Brasdor's operation, ii. 504; treatment of branching aneurism, ii. 554; proposal to bleed a patient to fainting, and operate during the syncope, iii. 603; case of excision of part of the lower jaw without the condyle, iii. 748. Warner's case of abscess mistaken for aneurism, ii. 474. Warren's, Dr., plan for bringing the edges of the cleft together in staphyloraphy, ii. 32; operation when the cleft is very large and complicated, ii. 33; treatment to be adopted when air enters a vein during an operation, iii. 604; case of re- section of the clavicle, iii. 764 ; of a rib, iii. 766; employment of ether by inha- lation prior to the performance of im- portant surgical operations, iii. 767. Warts, iii. 400. Wasserfuhr's operation and apparatus for re-breaking a badly-united bone, i. 576. Watson, Dr., on the local treatment of quinsy, i. 160; cases in which the carotid artery or a branch was wounded in scari- fying the tonsils, i. 160; difference be- tween synovial inflammation and inflam- mation of the ligaments, i. 241; objec- tions to Marochetti's views respecting hydrophobia, i. 414; cases of hemor- rhage during the operation of tapping, iii. 208. Wattmann's treatment of fractured clavicle, i. 603; method of replacement of the dis- located femur, ii. 239; operation on the humerus in anchylosis of the elbow, iii. 19. Weber's experiments show that the head of the thigh-bone is retained in its socket by atmospheric pressure, i. 285; of great importance in reference to diseases of the hip-joint, i. 285; on the production of callus, i. 550. Webster's case of dislocation of the ribs, ii. 216. Weckert's apparatus for fracture of the neck of the femur, i. 624, Wkdekind, von, on the treatment of crusta lactea, ii. 63. Wedemeyer on the number of times fric- tions with ung. hydrarg. may require to be practised in syphilis, ii. 96; case in which the aneurism burst after the liga- ture of the femoral, and amputation was performed, ii. 497. Weidmann's apparatus for ligaturing com- plete rectal fistula, ii. 169. Weilinger on the use of caustic to de- stroy the ends of broken bone in false joints, ii. 17. Weinhold on the introduction of the seton in false joints, ii. 20; mercurial cure in syphilis, ii. 98; cloacae in necrosis, ii. 127; case of old dislocation of the hu- merus, to reduce which the tendon of the pectoralis major was divided, ii 226; operations in diseases of the maxillary cavity, iii. 485. Welbank on sloughing phagedena, i. 84; case of part of a vertebra and rib in the rectum, iii. 108. Wells', Dr. case of epilepsy consequent on fissure of the skull, relieved by the tre- phine, i. 458; of an aneurism bursting into another artery, ii. 471. Wend on the treatment of abscesses at the hip, i. 298. Wenzel's diagnostic sign for vertebral caries, i. 311; on extirpation ofthe womb, iii. 568. Wernecke's plan for bringing the edges of the cleft together in staphyloraphy, ii. 32; instrument for drawing the knots. ii.32; operation for considerable narrow- ing ofthe mouth, iii. 24. Wernherr on morbus coxae senilis, i. 289. West on the extirpation of the ovary, iii. 210; case of extirpation of ovarian cyst, iii. 211. Wetzlar on the formation of urinary cal- culi, iii. 237 ; treatment of uric acid gra- vel, iii. 259. Whately on the use of the armed bougie in stricture of the urethra, iii. 79 ; cau- terizing the walls of the stricture, iii. 80; use of bougies armed with caustic pot- ash, iii. 80. White's operation for resection of the ca- rious head of the femur in hip disease, i. 300; case of cure of ununited fraeture, ii. 18; compensating collateral branches af- ter ligature of the brachial, ii. 532; ope- ration for ligature of the internal iliac, ii. 534 ; seat of stricture in the rectum, iii. 46; case of foreign body in the vagina, 936 ANALYTICAL INDEX. the bladder injured, and formation of a calculus, iii. 249; amputation just above the ankle, iii. 674; operations for the ex- cision of joints, iii. 726; case of excision of the head of the femur, iii. 737; of compound dislocation ofthe femur behind the leg, iii. 741; of excision ofthe lower jaw, iii. 750. White, C. on sawing off the ends of the broken bone in false joint, ii. 18; mode ofoperating in excision ofthe head of the humerus, iii. 732; excision of the head of the femur, iii. 737. ------'s, Dr. case of almost complete ex- tirpation ofthe upper jaw, iii. 754, White swelling, i. 304. Whitlow, i. 215. Wickham on inflammation ofthe ligaments, i. 231; disease ofthe cellular membrane of the joints, i. 234; case of synovial in- flammation terminating in ulceration, i. 239; of trepanning the spine, i. 590 ; of urinary calculus enclosed in a bag of lymph encrusted with calcareous matter, iii. 274; of bronchocele, which ultimately enlarged, after the ligature ofthe superior thyroid, iii. 393. Wickmann on the existence of the acarus scabiei, ii. 67. Wieseman on cauterizing the tonsils with the red-hot iron or caustic, i. 165, Willan, Dr. on eczema rubrum, ii. 109. Wilhelm on the nature of strangulation in rupture, ii. 629; mode of amputating by the circular incision, iii. 640. Williams', Dr. stimulant plan of treat- ment in simple erysipelas, i. 123; on hydriodate of potash in syphilis, ii. 101. Williams' experiments and conclusions on the condition of the lungs when the chest is opened, i. 482. Willis, Dr. on the formation of urinary calculi, iii. "237. Wilson on inflammation of cartilage, i. 254; the ulcerative absorption of carti- lage, i. 254; on sebaceous tumors, iii, 436; case of division of a nerve wounded in bleeding, iii. 636. Wilson's, Erasmus, statistical account of human horns, iii. 404; growth of horns from a previously obstructed follicle, iii. 405. Winslow on increased pressure and the supine posture in the radical cure of hernia, ii. 282. Winter's, von, case of reduction of the consecutive dislocation in hip-disease, i. 297; directions for wounded arteries, i. 333. Wiseman on incisions in carbuncle, i. 156; immediate amputation in gun-shot wounds, i. 380; spina ventosa, iii. 414. Wolf on twisting round of the patella, ii. 246. Wolf's Laud, case of extirpation of the cancerous womb, iii. 569. Wolff's case of imperforate anus, iii. 34. Womb, abscess of, i. 532 ; prolapse of, ii. 369; closure and narrowing of the mouth of, iii. 90; polypus of, iii. 486 ; cancer of, iii, 561 ; extirpation of the neck of, iii. 566; ofthe whole organ, iii. 569. Womb, Changed direction of, ii. 406; changes of direction to which the womb is subject, ii. 407 ; retroversion, ii. 407 ; Dr. Rigby on retroversion in the unimpreg- nated state, ii. 407 ; Dr. Blundell on the local symptoms caused by retroversion, ii. 407; predisposing and occasional causes, ii, 407 ; symptoms of the chronic inflammation which precedes retrover- sion, ii. 407 ; symptoms of retroversion, ii. 408; Mende on the seeming retro- version at the later periods of pregnancy, ii. 408 ; Blundell on partial retention of urine in retroversion, ii. 408 ; Lacroix on the nervous symptoms attending sudden retroversion, ii. 409 ; situation of the womb as ascertained by vaginal examina- tion, ii. 409; Rigby on examination by the vagina and rectum, and by the uterine sound in retroflexion, ii. 409 ; symptoms of retroversion, ii. 410 ; Rigby on the symptoms of, ii. 410; prognosis, ii. 411; Blundell on the prognosis in, ii. 411; treatment, ii. 411; catheterism, ii. 411 ; exhibition of enemata, ii. 411; reduction of the retroverted womb, ii. 411; Bell- anger and Hal pin on the reduction, ii. 412; Jourel and Baynham's cases of puncturing the womb in, ii. 412 ; the replacement of the retroverted womb per vaginvm preferable, ii. 413 ; treatment in women not pregnant, ii. 413 ; after-treat- ment, ii. 414 ; Rigby on the mechanical support to the womb requisite after re- duction, ii. 414; anteversion ofthe womb, ii. 414; causes and symptoms, ii. 414; Blundell, John Burns, Boivin, Duges, and Gray on anteversion, ii. 415; treat- ment, ii. 416 ; Boivin and Duges' cases of spontaneous cure, ii. 416; Godefrey's cases cured by position, ii. 416; antro- version of the womb in the unimpregnated state, ii. 416; causes, ii. 417; reduction, ii. 417 ; Gray on Hull's'utero-abdbminal supporter, ii. 417. Wtomb, wounds of, i. 529 :—the unimpreg- nated womb not easily wounded, i. 529 ; danger of injury to the impregnated womb, i. 529; if the wound in the womb be so large, that the foetus is partially or ANALYTICAL INDEX. 937 wholly in the abdomen, it must be ex- tracted, i. 529 ; Duparque on the fibrous and cartilaginous resistance ofthe tissue of the womb, i. 529; Latour and Du- parcque's cases of accumulation of blood in the womb, i. 530; Duparcque on rup- ture ofthe womb during pregnancy, i. 530; Duparcque on the danger and immediate treatment of rupture, i. 530; Powell's case of rupture not fatal, i, 531; Dr. Rigby and Dr. Merrem on wounds ofthe uterus as predisposing to rupture in sub- sequent labours, i. 531 ; Birch's case- of fatal rupture, subsequently to one previ- ously recovered from, i. 531 ; Merrem's explanation of this, i. 531 ; Duparcque on partial rupture of, from a collection of fluid in its parietes, i. 532; Morere and Duparcque's cases of abscessof the womb, i. 532 ; rupture of the impregnated womb from external violence, i. 532; Naegele's jun. case of womb in the eighth month of pregnancy ruptured by external vio- lence, i. 532 ; Duparcque on punctures or narrow lacerations ofthe womb, i. 533; Planchon's case of fatal punctured wound, i. 533 ; Deneux and Schmucker's cases of wounds, i. 533 ; wounds and ruptures ofthe vagina, i. 533 ; causes, i. 533 ; con^- sequences, i. 533 ; South on rupture of the perineum, i. 533. Wood, Dr. on the chemical and microscopie characters of pus, i. 46. Wood, Kinder, on an epidemic vaginal catarrh, i. 182; operation of excising a portion of the tunica vaginalis in hydro- cele, iii. 225. Woolaston's, Dr. C. cases of gangrene, i. 75. Wormald's operation for varicocele, ii. 329; Wounds :—definition of, i. 317; varieties of, i. 317 ; South on the German distinction between incised wounds, i. 318; wounds distinguished as simple and'complicated, i. 318 ; also according to their direction and depth, i. 318; also by the nature of the divided parts, i. 318; symptoms, i. 318 ; consequences of, i. 318; inflamma- tion and sympathetic fever, i. 319; ner- vous symptoms attending wounds, and their causes, i. 319 ; Hunter and Meckel on the three kinds of union of divided' parts,—quick union, by adhesion, and by granulation, i..319; Hunter on quick. union, i. 319; objected to by Dr. John Thomson, i. 320 ; Astley Cooper on the union of wounds, i. 320 ; Travers on the blood as a medium of organized adhesion. in, i. 320 ; quick union, i. 320 ; South on the meaning of " quick union, 1.321, Hunter on the adhesive inflammation in 79 connexion with wounds, i. 321 ;. Astley Cooper on adhesive inflammation, i. 321; Dr. Bennett and Wharton Jones on the process of union by adhesion, i. 321,322 £ Lawrence's objection to the term "inflam- mation" in reference to union by adhe- sion, i. 323; Bennett on the formation of new vessels, i. 323; opinions of John Hunter, Schwann, Doellinger,. Kalten- brunner, Pockels, Liston, Travers, Hasse, Henle, Skoda, and Kolletschka, i. 323; union by granulation, i.. 323; nature of the cicatrix, i. 323 ; Jbhn Hunter on sup- puration and. granulation as leading to cicatrization, i. 324; Travers on the filling- up a gaping wound, i. 324; Bennett on the process of granulation and cicatrization, i. 325; Wharton Jones on healing by the second intention or granulation, i. 326 ; points to be noticed in the prognosis, i. 326; treatment i. 327; examination of wounds, i. 327; treatment of the bleeding, i. 327; mode of arresting haemorrhage adopted by na- ture, i. 327; changes in the blood-clot in the canal of the artery, i. 327 ; Petit, Morand, Sharp, Gooch, Kirkland, Pou- teau, John Bell, Textor, and Hummel on the arrest of haemorrhage by nature, i. 329; wounds of arteries and their conse- quences, 329; closure of slight and lon- gitudinal wounds, i. 329 ; Saviard, Petit, and Scarpa on the healing of wounds of, i. 330 ; means of arresting haemorrhage, i. 330; compression, i. 330 ; Ehrlich's com- pressor, i. 330; the tourniquet, i. 330;; different kinds of tourniquets, i. 330; mode of applying the tourniquet, i. 331 ; South on the application of, i. 331; the artery-compressors of Langenbeck, Ver- dier, Mohrenheim, Dahl, Wegenhausen, Moore,Graefe, Scultetus, Heister, Dionis, Plattnen Brambilla, Desault, Liber, Ayres, Bell,Chabert, Lampe, Faulquier, Schindler, Hesselbach, and Joachim, i. 331 ; Carlisle's tourniquet, and its mode of application, i- 332; the ring tourni- quet, i. 332; Oke's arch tourniquet, i„ 332; use of the compressor cannot be persisted in sufficiently long, i. 332 ; treat- ment of wounds after the bleeding has ceased, i. 332; von Winter's directioi s for wounded arteries, i. 333; immediate or direct compression, i. 333; South on the treatment of protracted oozing of blood; ii 333 ; pressure on the meningeal artery inadmissible and not requisite, i. 333; Abernethy's case of wounded me- ningeal artery*, i. 333; South on the treat- ment of epistaxis, i. 334; South on wounds-of the pudic artery, and artery 93 S ANALYTICAL INDEX. of the bulb during the lateral operation for the stone, i 334 ; South on the treat- ment of wounded arteries in the thick fleshy parts of the hand or foot, i, 334; ligature of arteries, i. 335; experiments of Jones, Crampton, and Scarpa on the ligature of, i. 335; South's experiment on the carotid of a dog, i. 335 ; difference of opinion, as to the action of the ligature, i. 335; English surgeons so apply the liga- ture, as to divide the inner arterial coat, i. 336 ; Cline's experiment with the broad ligature, i. 336; Scarpa's experiment with the ligature and cylinder of linen, i. 336; Manec, Dupuytren, and Roux on the in- troduction of a piece of bougie into an ossified artery after amputation, i. 336; experience in favour of the simple pound ligature, i. 336; application of the liga- ture, i. 336 ; varieties of forceps for hold- ing the artery, i. 336; South on the appli-. cation of the ligature, i. 337; treatment of a retracted artery, i* 337 ; South on the ligature of large arteries above and below the wound, i. 337; South on the necessity for cutting down upon a wounded vessel on the sound side of a limb, if nearer the 3rtery than is the part wounded, i. 338; Travers' case of wound of the posterior tibial, i. 338; after-management of the ligature, i. 338; Lawrence, Hennen, Del- pech, Walther, Haire, Guthrie, and South on the after-management of, i. 338, 339 ; Dr. M'Sweeny on the silk-worm gut ligature, i. 339; Physick on the animal ligature, i, 339; Astley Cooper on the catgut ligature, i. 339; length of time be- fore the separation of a ligature, i. 340; Callaway a^id Guthrie's cases, i. 340; severe pain caused by attempts to take away the ligature, a nerve being included in the noose, i. 340; Chopart's case, i. 340; Lord Nelson's case, i. 340; second-. ary haemorrhage on the separation ofthe ligature, i. 340; Green's case of se- condary-haemorrhage after ligature of the subclavian, i. 340; South's opinion that the ligature should be allowed to come away, as the result of the suppu- tingprocess, i. 340; Seuth on the manage- ment of a long-retained ligature, i. 340; torsion or twisting of arteries, i. 341; Galen, Amussat,Thierry, Liber,Velpeau, Fricke, and Dieffenbach on torsion, i. 341; changes produced by, i. 341 ; John Hunter on the suppression of haemorrhage, i. 341; Palmer on torsion, i. 342; Amus- sat, Thierry, and Fricke on the mode of practising torsion, i. 342; Dieffenbach's torsion-forceps, i. 342; Kluge's torsion- . apparatus,,i. 342; advantages of torsion, i. 343; Dupuytren, Loreh, Textor, Fricke, Elston, and Bramberger on the effects of, i. 343, 344; Dieffenbach, Dupuytren, and Chelius' objections to, i. 344 ; South on, i. 344; Feme and Astley Cooper's cases of accidental torsion, i. 344; cases in which torsion is preferable, i. 344; Kohler and Fricke on the torsion of bony vessels, i. 344; Stilling on the interweaving of arteries, i. 344 ; use of astringent styp- tics, i. 345; effects of cauterization on wounded vessels, i. 346; occurrence and management of secondary haemorrhage, i. 346; circumstance favouring the oc- currence of secondary haemorrhage, i. 346; Cline's, jun. cases of after-bleeding, in which the actual cautery was employed, i. 347; Cline's, jun. clinical observations, on after-haemorrhage, and on the use of the actual cautery in such cases, i. 347; Cline's, jun. experiments on arteries, i. 351; South on the treatment of bleeding ossified arteries, i. 352; bleeding from wounded veins, i. 352; indications of venous haemorrhage, i. 352; bleeding from the smaller veins usually stops of itself, from the large ones, such as the internal jugular, the subclavian, and the femoral,is soon fatal, i. 352; compression usually employed to arrest venous hae- morrhage, the ligature rarely, i. 352; dis- advantages of the ligature, i. 352; South on venous bleeding in operations, i. 353; South's case of fetal venous bleeding during amputation of the breast, i. 353; Green's case of ligature of the external jugular vein, i. 353; use of the ligature by Celsus, i. 353; Thomas Gale and Pare on the use of the ligature for wound- ed vessels, i. 354, 355; invention ofthe tenaculum by Bromfield, i. 355; removal of foreign bodies from wounds, i. 355; great care required- in doing, so, i. 356; condition ofthe wound a guide as to the treatment, whether for quick union, or by suppuration and- granulation, i. 356; the cleaner the wound, the more is it disposed for quick union, i. 356; slight bruises may admit of quick union, but those with the greatest degree of- bruising and tearing do not, i.356; simultaneous injury of the bone-does not counter-indicate union, i. 356;. deleterious matter in the wound counter-indicates union* i. 356; treatment of-a wound to induce union, i. 357; Hun- ter, on the means for keeping the lips of a wound in apposition, k 357; position of the wounded parts, i. 357; uniting bandages, i. 357; application of the band- age, i. 358; South on the use of bandages for wounds, i. 358; application of stick- ANALYTICAL INDEX. 939 ing-plaster to keep the lips of wounds in apposition, i. 358; Gale on dressing wounds, i. 358; John Hunter on the use of sticking-plaster or the dry suture for wounds, i. 359; Tyrrell and Liston's plasters, i. 359; cases in which the suture should be used, i. 359; J'ohn Hunter on the use of sutures, i. 360; South on the advantages and disadvantages of sutures, i. 360; South on the number of sutures to be used, and the mode of their applica- tion^.361; Dieffenbach's thin insect-pins and the twisted suture, i. 361; varieties of suture, i. 361; application of the in- terrupted suture, i. 361; Gale on the application of the interrupted suture, i. 362; the quill suture, i. 362; dressing the wound after the application of su- tures, i. 362; subsequent treatment, i, 362; treatment of a wound healing by suppuration and granulation, i. 363; South's objections to stuffing a wound which must heal by suppuration, i. 364; incised wounds, i. 364 ; longitudinal and transverse wound* of tendons, i. 364; mode of union of transverse wounds, i. 364; treatment of wounded tendons, i. 364; Ever's apparatus for divided and ruptured tendons of the hand and fingers, i. 364 ; effects of the division of a large nerve, i. 361; South on the regeneration of nerves, and- the recovery of their funo- tion after division, i. 364; Haighton's experiments on the division of both pneumo-gastric nerves, i. 365; Meyer on the application of nitric acid to the scar of nerves, i. 365; Larrey on the union of the nerves of a stump in loops, i. 365; treatment of flap wounds, i. 365"; re- union of separated parts, i.,365; punctured wounds, i. 366; definition, i. 366; treat- ment, i. 366; punctured wounds of parts of tough structure, or surrounded by un- yielding aponeuroses, i. 367; punctures of tendons, ii 367; of nerves, i. 367; treatment of punctured wounds of nerves, i. 367; of punctured vessels* i. 367; en- largement of a punctured wound only necessary for the removal of"foreign bo- dies, to arrest hemorrhage, or to relieve strangulation in parts of an unyielding texture, i. 367; the introduction of a seton to be practised only when the walls of this fistulous-passage are callous, i. 367; lacerated and contused wounds, i. 367; definition and character, i, 367; union to be attempted only in wounds without much bruising or tearing, i. 368; gene- rally heal by suppuration and granula- tion, i. 368; treatment, i. 368; removal of foreign bodies, i. 368; South on the tearing or stripping down of large pieces of skin, i. 368; South on torn wounds of the scalp, i. 368; South on the slough- ing which generally follows extensive laceration of the skin of the limbs, i. 368; bruises with-extravasationof blood, i. 369; treatment, i. 369; if a large artery be wounded, it may be necessary to expose it, and take it up, i. 369; if suppuration take plaee in the swelling, it must be treated as an abscess, i. 369; South on extensive ecchymosis, and the means of diagnosis, when an artery of any material size is wounded, i. 369; treatment of the swelling, i. 369; danger of gangrene when a large artery has been wounded, from the distention of the soft parts, i. 369; gun-shot wounds, i. 369; definition, L 370; John Hunter on gun-shot wounds, i. 370; Dupuytren on the effects of gun-shot, i. 370; Du- puytren's case of a person killed by a gun loaded with powder only, i. 371; South's cases of severe injury from small shot, i. 371; pain and haemorrhage at- tendant on a gun-shot-wound, i. 371; form of the wound, i, 372; shock from the wound, i. 372; subsequent symptoms, i. 372; Guthrie on the pain attending gun- shot wounds, i. 372; Guthrie on the at- tendant haemorrhage, i. 372; Guthrie and Hennen on tire shock caused by a gun- shot wound, i. 372, 373^; Hunter on the character of gun-shot wounds, i. 373; H. Larrey's cases of regular-shaped'gun-shot wounds, i. 373; direction of the shot, i. 373; general kinds of injury from shot wounds, i. 374; division of shot wounds into simple and complicated, i. 374; Rust and' Busch*s explanation of wounds from the wind of the ball, i. 374; Hennen on severe bruising from shot, i. 374; Guthrie on the appearances caused by the passage of a ball, i. 374; Dr. Thompson and Du- puytren on the splitting of the ball by the sharp edge of a bone, i. 374,375; Guthrie on the resistance offered to the passage of the ball by bone or an elastic body, L 375; shot wounds generally complicated by foreign bodies in their cavity. i. 375; prognosis, i. 375; indications of treatment, i. 375-; circumstances under which the enlargement- of the wound1 may be neces- sary, i. 375*; Hennenon the treatment of wounds by a ball in the fleshy part of the arm, thigh, or buttock, i. 376; general and'local treatment, i. 376; occurrence of suppuration, l 376; of secondary haemor- rhage, i. 376; Guthrie, Samuel Cooper, and1 Dupuytren on. secondary haemor- rhage, i. 376, 377; local and general treat- 940 ANALYTICAL INDEX. mentduring the suppuration, i. 377; Hen- nen and Dr. Arthur on the use of the seton to bring away separated pieces of bone, i. 377; Staff-Surgeon Boggie's cases,i. 377; treatment of shot wound complicated with j fracture, i. 377; Hennen on the occur-) rence of necrosis -in gun-shot injuries of | bones, i. 378; bleeding from the whole! surface of the wound in long-continued | suppuration, i. 378; the circumstances in gun-shot wounds requiring amputation on the spot, i. 378; Hennen on the nature of the injuries in gun-shot wounds requiring amputation, i. 379; amputation,under the circumstances mentioned, should be per- formed early, i 380; Wiseman, Le Dran, I and Ranby on immediate amputation, i.| 380; Faure on the propriety of delay-j ing the operation, i. 381; Bilguer's ob- jections to amputation altogether, i. 381; Hunter's objections to primary amputa- tion, i. 381; Hennen, Pitcairn, Gunning, and Guthrie on immediate amputation,] i. 381; Guthrie's reasons for an early per- formance ofthe operation, i. 382; symp-| toms which may require the performance of amputation at a time more or less pos- terior to the date of the injury, i. 383; poisoned wounds, i. 383; definition, i. 384; dissection-wounds, i. 384; symp- toms and treatment, i. 384 ; cause of the symptoms after injuries in dissection, i.l 384; South objects to the application of] caustic in dissection-wounds, i. 385; J. Shaw on dissection-wounds and their treatment, i. 385; Basedow considers dissection-wounds agree with malignant pustule, i. 385; South and Lawrence on the absorption of poisonous matter in dis- j section-wounds, i. 385; details of Dr. Pen's case, i. 386; South on the mosti dangerous punctures, those received in! cases of simple or puerperal peritonitis, i. 386; South on the consequences of dis- section-wounds, i. 386; stings of bees, wasps, &c, i. 387; Dr. Gibson and Law- rence on the fatal effects of the stings of bees and wasps, i. 387; Dr. Moseiey's case of scorpion-sting, i. 387; Allan, Curling, Kirby,and Spence on theeffects ofthe scorpion-sting, i. 387; bites of the1 gnat, mosquito, harvest bug, bete-rouge, and American tick, i. 388 ;- Dr.. Moseley on the chigoe, i. 388; symptoms follow- ing the bite of a viper, i. 389; local and general treatment, i. 389 ; Pennock and , Rodrigues on the effects of cupping- glasses in viper-bites, i. 389; Fontana on{ the effects of viper-bites, i. 389; Vincent's I case, i. 389; South on viper-bites, and their treatment*, i. 389*; ©r. Mead on. viper's fat a local remedy in viper's bite, i. 390; Celsus, Astley Cooper, and Home on the application of a ligature above the bite, i. 390; suction of venomous bites, i. 390; Celsus' observation on the inno- cuous qualities of the poison of serpents when introduced into the mouth, con- firmed by Russel, i. 390; Dr. Mead's case of the bite of a rattlesnake, i. 390; Sir David Barry on the application of the cupping-glass over snake-bites, i. 391; Dr. Mead's experiments on viper- poison, i. 391 ; snake-bites and their treatment, i. 391; Dr. Barton on the symptoms produced by the bite of the rattlesnake, i. 392; Professor Owen's case of viper's bite, i. 392; Home's case of bite of the rattlesnake, i. 392; Dr. Russell on the symptoms produced by the bite of a cobra de capello, i. 394; Russell's eases of fatal snake-bite, i. 395 ; Barton on the treatment of rattle- snake-bites, i 395; Russell on the treat- ment of snake-bites injlndia with theTan- jore pill, i. 395; Ireland on the use of arsenic in the bites of the great lance- headed viper of Martinique, i. 396 ; Rus- sell on the physical qualities of snake-poi- son, i. 396; Barton on the employment of the ligature in snake-bites, i. 396; bite of a rabid beast, 396; bite of beasts much excited, or when disturbed during copula- tion, may produce canine madness, i. 397; cause of dog-madness, i. 397; spontaneous development of hydrophobia in man,i.397; signs of incipient madness in the dog, i. 397; Hertwig on canine madness, i. 397; progress of the disease, i. 398; signs of dumb-madness in the dog, i. 398; Youatt on rabies in the dog, i, 398; Youatt on the peculiar bark of the mad-dog, i. 399; Youatt on the saliva of the mad-dog, i. 400; Youatt on the condition of the lum- bar portion of the spinal cord in rabies, and dumb-madness in the dog, i. 400; Youatt on a peculiar paralysis of the muscles of the tongue and jaws occasion- ally occurring in mad dogs, i. 400; Youatt on the insensibility to pain in mad- dogs, i. 400; Youatt on the diagnosis between pain in the ear in canker and in hydrophobia in the dog, i. 401; Youatt on the period of incubation of rabies in the dog, i. 401; Hertwig's experiments show that the saliva is the vehicle ofthe mad poison, i. 401; Trolliet considers the mucus from the inflamed mucous mem- brane of the bronchi the vehicle of the poison, i. 401; Hertwig's experiments also show the contagion to be in the blood of the mad beast, i. 401; Youatt ANALYTICAL INDEX. 941 excision, i. 411; South on excision of the scar, i. 412; internal prophylactics of hydrophobia, i. 412; plan of treatment recommended by Wendl, i. 412; Brera and von Schallein's treatment, i. 412; Marochetti on the presence of pustules under the tongue after the bite of a mad animal, i. 413; Marochetti's plan oftreat- ment, i. 413; Watson's objections to Ma- rochetti's views, i. 414; general treat- ment, i. 414. Wright, Dr. on ligature of the external iliac, ii. 538; case in which he performed the operation of lithectasy, iii. 376. Wright on amputation just above the ankle, iii. 674. Wrist, fracture ofthe bones of, i. 615; dis- location of, ii. 232; exarticulation of the hand at, iii. 721; excision of, iii. 734. Wry neck, ii. 421. Wutzer on the use of the suture in vesico- vaginal fistula, ii. 192; puncture of the bladder above the pubes after this opera- tion, ii. 194; after-treatment, ii. 195; on congenital dislocation of the knee, ii. 248; modification of Gerdy's operation for the radical cure of rupture, ii. 284. excision, i. 411; South on excision of the scar, i. 412; internal prophylactics of hydrophobia, i. 412; plan of treatment recommended by Wendl, i. 412; Brera and von Schallein's treatment, i. 412; Marochetti on the presence of pustules under the tongue after the bite of a mad animal, i. 413; Marochetti's plan oftreat- ment, i. 413; Watson's objections to Ma- rochetti's views, i. 414; general treat- ment, i. 414. Wright, Dr. on ligature of the external iliac, ii. 538; case in which he performed the operation of lithectasy, iii. 376. Wright on amputation just above the ankle, iii. 674. Wrist, fracture ofthe bones of, i. 615; dis- location of, ii. 232; exarticulation of the hand at, iii. 721; excision of, iii. 734. Wry neck, ii. 421. Wutzer on the use of the suture in vesico- vaginal fistula, ii. 192; puncture of the bladder above the pubes after this opera- tion, ii. 194; after-treatment, ii. 195; on congenital dislocation of the knee, ii. 248; modification of Gerdy's operation for the radical cure of rupture, ii. 284. Youatt on rabies in the dog, i. 398; on the peculiar bark of the mad dog, i. 399 ; on the saliva of the mad dog, i. 400 ; on the condition of the lumbar portion of the spinal cord in rabies and dumb madness in the dog, i. 400; on a peculiar paralysis of the muscles of the tongue and jaws occasionally occurring in mad dogs, i. 400; on the insensibility to pain, i. 400; on the diagnosis between pain in the ear in canker and in hydrophobia in dogs, i. 401 ; on the period of incubation of rabies in the dog, i. 401; on the appearances on dissection, i. 401; caution against suffer- ing dogs to lick the face or hands, or any other part of the body, i. 403; on the peculiar delirium in hydrophobia, i. 407; on the tenacity of the human saliva in hydrophobia, i. 407; objections to the excision of the bitten parts, i. 410. Young, Dr., on the genus carcinoma, iii. 455. on the appearances on dissection in the doof, i. 401 ; Yrouatt's caution against suffering dogs to lick the face, or hands, or any other part of the body, i. 403; Lawrence's details of the Hon. Mrs. Duff's case, i. 403; Lawrence on the communication of hydrophobia from one human being to another, or from man to beasts, i. 403;'Magendie and Breschet's experiment, i. 403 ; period of incubation of hydrophobia in man, i. 403; Galen, Mead, and Hale Thomson on the pro- tracted period of incubation of hydro- phobia, i. 404; Dr. Bardsley's case of the disease twelve years after the bite had been inflicted, i. 404; his opinion that the disease was not hydrophobia, i. 404; sup- ports his view by the opinions of Darwin, Haygarth, and R. Pearson, i. 404; Elliot- son on the period of incubation, i. 404 ; Dick on the nature of the disease in hy- drophobia, i. 405; symptoms of incipient hydrophobia, i. 405; Urban's opinion that there is a circlet of small vesicles around the wound or scar, i. 405; general symptoms, i. 406; Elliotson on the symp- toms of, i. 406 ; Elliotson on the diagno- sis between true and spurious hydropho- bia, and inflammation of the pharynx, i. 406; disposition of hydrophobic patients to bite doubted by South, i. 406; Powell and Magendie's cases, i. 407; Cline, jun. on the dispositionof hydrophobic animals to use their weapons of offence, i. 407; Elliotson on a general morbid irritability in hydrophobia, i. 407; Youatt on the peculiar delirium in, i. 407; Bardsley and Babington's cases, illustrative of this delirium, i. 407; Lawrence on the pecu- liar delirium of hydrophobia, i. 407; Youatt on the tenacity of the human saliva in, i. 407; Elliotson on the dura- tion of the disease, i. 407; Mead on the increase of muscular strength in hydro- phobia, i. 408; Elliotson on abortive hy- drophobia, i. 408; Dr. Bardsley on the stages of hydrophobia, i. 408 ; Marcet, Babington, and Callisen on the premoni- tory pains of, i. 408; post-mortem appear- ances, i. 409; Locher on vesicles of the spleen in hydrophobia in dogs, i. 409; the post-mortem appearances in Elliotson's case, i. 409; proximate cause, i. 409; Harder on the action of the poison on the system, i. 409; Langenbeck on hydro- phobia as caused by a qualitative altera- tion of the Wood by the poison, i. 410; prognosis, i. 410; treatment of the bite, i. 410; Youatt*s objections, to excision of the bitten parts, i. 410; South on ex- cision, i. 411; Cline's directions for the Young on compression in scirrhus, iii. 511. Zang on laying open a cold abscess lon- gitudinally, i. 105; on the more general application of the trephine, i. 454; on suture of urethral fistula, ii. 178 ; on the treatment of recto-urethral and recto-vesi- cal fistulae, ii. 185; on ligature of the common carotid, ii. 509 ; mode of ampu- 942 ANALYTICAL INDEX. tating the thigh with the flap from the inner side, iii. 660. Zeiss on the introduction of'charpie under the edge of the nail, and on the use of foot-baths in treating ingrowing of the nail, i. 223 ; on the operation for removing the diseased nail, i. 223; case of ligature of the carotid, ii. 508. Zeller's operation for united fingers and toes, iii. 17. Zembsch's opinion on the lymph-swelling, i. 61. Zimmermann on the elimination of the molecular fibrin, i. 43. Zink on the situation and direction of sco- liosis, ii. 433. Zittmann's decoction in the treatment of syphilis, ii. 100 ; formula for it, ii. 100; mode of employing it, ii. 100. THE END. i MAY 20 1960