a W(V.i''M' 1.V-t.%,.,h1v.l, • iiir.;-v;.i.y ,iiiW'M'*!iV'iij»«rii'';jViiifl k.'1.VVlT,>>Tn..rt.. li^iAfiirjrrtti-'lv . .**pff#p*..... {mivti riwW'iiii in ... ';iwtwmni*A:»inm>i' n\*. i KfiVti'i^Si^ntMft'niv'.'iiviHmtv ifi • jv i ., ■ «»<«■"• V :^"»^&*Hr ,.iy-»>5 MS Hi(t WITn-.M. ■ >Mi ■■■ "> wmw NATIONAL LIBRARY OF MEDICINE NLM 0D5b0527 3 v ARMY MEDICAL LIBRARY FOUNDED 1S36 WASHINGTON, D.C NLM005605273 „ ^Xa-^^v^^ DUE TWO WEEKS FROM LAST DATE r 9 6 VQ5? 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Y/oY/Y /f///Y JY//yYY/yY, )//yY//Y. ^t(MO(V(?d, ^/77yy/ yy yyyyy yyy//Yyy y/'//yyy /y yy/y/y yyyy /yy/'/yy //yy /'Yyyyyy //■>' yyyyyy //yyyy yyy y Yyy /yy y yy yyy/y yyyyy Y. yy yy// yy/y yy/ y/y y y yy yyy y yy/yyyy yyyy/^ •///////' ^yVyy/A/y/y. yA, -f.( (/yyyyy/yyy ' '/..JY/YsyrY/y ////. />!// DY MEDICAL INSTITUTE, LATE SURGEON OF THE U. 8. ARMY, IIC, ETC. " Canst thou not minister to a mind diseased, Raze out the written troubles of the brain, And with some sweet oblivions antidote Cleanse the stuffed bosom of that perilous stuff Which weighs upon the heart? " — Shakespeare. BOSTON, MASS.: PUBLISHED BY THE PEABODY MEDICAL INSTITUTE, No. 4 Bulfinch Street. 1878. WM l?7? Entered according to Act of Congress, in the year 1873, by ALBERT H. HAYES, In the Office of the Librarian of Congress at Washington. PREFACE. The author has long entertained the opinion that a, popular work on " Nervousness, or the Pathology of the Nerves, and Nervous Maladies," is a desideratum. Of technical works on this subject, intended for the medical profession, the name is legion But he knows of no popular treatise for the general and unprofessional reader. In the following pages he has endeavored to furnish such a work to the public. Having made the cure of Nervousness a spe- cialty throughout his entire professional course, and having had an enviable success in this specialty, he has, of course, drawn largely from his own experience in writing the following chapters. But he has had no hesitation in drawing on the experience of other practitioners as detailed in their writings, whether in the form of independent treatises, or as contributions to jom-nals of psycholog- ical medicine, whether published in English, French, or German. Tt has always been his maxim to supplement and fortify his own experience by that of others. Never was psychology, or the sci- ence of mind, pursued with more fruitful results than it now is, in connection with physiology. The Nerves and Brain, which are the organs of the mind, demand as much study as the mind itself. Psychology and Physiology now go hand in hand, and shed mu- tual light on each other. The subject of the Nerves, and their Dis- eases and Derangements, the writer unhesitatingly pronounces to be at this fast and eventful epoch, when'life is condensed, as it were, the most important in the whole range of medical pathology. Mind and body are such intimate companions, that they sympathize, so to speak, with each other perfectly. If one is sound and buoyant, the other is ordinarily in the same condition, and vice versa. If the nerves, which are the organs of the mind, are healthy and vig- 5SZIXY iv PREFACE. orous, the mind is bright and hopeful. On the contrary, if the nerves are jaded, diseased, and unstrung, the mind is in the same state. Mental pathology is necessarily a sad record of human wretchedness and woe ; for what torments are like those caused by " a mind diseased " ? It has been the writer's aim to make his work interesting, as well as instructive. He has dealt with nervous dis- ease in all its thousandfold and most perplexing forms and man- ifestations, and should know whereof he writes. Under the dread name of Nervous Disease, what an awful category of human ills is included ! Insanity ; suicide ; narcotism ; alcoholism ; epilepsy ; pa- ralysis ; softening of the brain; soul-crushing mental anxiety; " that strange melancholy," " which rejoiceth exceedingly, and is glad when it can find the grave," to quote from the Hebrew Scrip- tures ; that utter wreck of the will and helplessness, which is the result of self-abuse, and which is a cause of a majority of the cases of nervousness and general debility; all these momentous subjects, of course, are full}'' and popularly discussed in the following pages. One word before closing on the subject of special medical prac- tice. The special medical practitioner, who, confident in his power of dealing successfully with the particular class of diseases to which he devotes himself, seeks, by all legitimate and proper means, to bring himself and his skill to public notice, must calcu- late beforehand on incurring the occasional sneers and unkindly criticism of jealous professional brethren. If such things can even annoy him for a moment, he has mistaken his calling. A profes- sional man is either a public man, or he is nobody. If a physician has especial skill in treating, say, the diseases of the nervous sys- tem, the public want to know the fact, and ought to know it. In such a case, it is a duty to seek publicity, for it is a means of doino- good. The skilful, special practitioner will have triumphs enough, in the long run, over those who sneer. He will oftentimes find such reluctantly compelled to avail themselves, and their patieuts in extreme cases, of his superior skill in his own particular prov- ince. In such cases he gets his revenge by affording the desired relief. Peabody Medical Institute, July 30, 1873. PRESCRIPTIONS. The following Prescriptions have proved, by the most extensive experience, to be thoroughly efficacious in the treatment of the diseases the names of which are appended to them. They are written in English, Latin names and scientific terms being purposely avoided, and they can be obtained at all reliable drug-stores throughout the country. While the following formulae are of established merit, the reader should bear well in mind that it is important that they be only applied for the dise»ses for which they are recommended, hence the importance of a correct knowledge of their complaint before using tbem. Prescription No. 1. R Tinct. Musk, 5i. Tinct. Hops, Siii. Liq. Potassae, 3ii. lufus. Buchu, Svi. Mix: Three tablespoonfuls after meals. Very useful in Indigestion attended with Nervousness and Flatulence. Prescription No. 2. R Gum Arabic, 5i. Water, Oiss. Simple Syrup, 5ii. Mix: A wineglass frequently. In Stranyuary and Irritant Poisoning. Prescription No. 3. R Gum Arabic mixture, 5iss. Water, Siiiss. Syrup, 5ss. Mix: A tablespoonful frequently. In Bronchial Catarrh of Children. Prescription No. 4* R Gum Arabic mixture, 5ii. Water, Si v. Syrup Tolou. Orange Flower Water, aa3i. Mix: A tablespoonful every two hours. Excellent in Slight Colds. Prescription No. 5. R Vinegar, 3i. Water, 5xv. Sugar, 3ss. Mix: To be taken as a common drink. Very useful in Fevers to allay thirst. Prescription No. 6. R Distilled Vinegar, 3 ii. Syrup, 3ss. Water, gii. Mix: A fourth part every three hours. In Scarlatina (for a child of three years). Prescription No. 7. R Dilute Acetic Acid, 3i. Tinct. Jalap, ITlxv. Tinct. Orange Peel, 3i. Mix; ure Camphor, 3x. Mix: Make a draught to be taken 2 or 3 times a day. In Rheumatism in debilitated persons. Prescription No. 8. R Vinegar, 3ii- *' Ammonia Muriate, 3i. Honey, Siss. Water, gxii. Mix: Use as a gargle 3or 4 times daily. Good for a Sore Throat. Prescription No. 9. R Lemon Juice, 5n. Camphor Mixture, 5i. Mix: Make a draught, to be taken 3 times a day. In Acute Rheumatism. Prescription No. 10. R Recent Lemon Juice, 5i. Oil Sweet Almonds, 5iss Syrup Marshmallow, 3ss. Mix: A teaspoonful every 3 hours. In Obstinate Diarrhoea. R Prescription No. 11. Camphor Mixture, 5i. Spts. Ether Com p., S ii. Tinct. Cardamon Comp., 3iv. Spts. Anise, 3vi. Oil Carroway, Vt[x\\. Syr. Ginger, 3ii. Peppermint Water, Svss. Mix: Take two tablespoonfuls. For Troublesome Flatulence. PRESCRIPTIONS. Prescription No. 12. R Sulph. Morphia, grs. ii. Sulph. Soda, 3ii. • Syrup Simple, 3ii. Mix: Dose, i a small teaspoonful to an adult after each discharge. Invaluable in Dysentery. Prescription No. 13. R Liquid Tar. Powd. Alum, aa3v. Powd. Liquorice, q. s. Mix: Divide into 100 pills. Take from 6 to 10 every day. Excellent in Gonorrhoea. Prescription No. 14. R Camphor Mixture, Siss. Liquid.Acetate Ammonia, 3iv. Wine Antimony et Potassia Tart. drops xl. Tinct. Opium, drops xx. Mix: Take half of the quantity on retiring. Very beneficial in Acute Rheumatism. Prescription No. 15. R Antimony Potassia Tart., 1 gr. Saltpetre, 3ii. Almon I Mixture, Sxii. Tinct. Camphor Comp., 3ss. Mix: Dose, a tablespoonful every hour. Excellent Cough Mixture. Prescription No. 16. R Horse-radish Root. Contused Mustard Seed, aajiii. Warm Water, 01. Macerate for an hour, and strain. Colaturas, Svii. Spts. Ammonia Arom., 3iss. Spts. Pimentse, Siii. Mix: Two tablespoonfuls 3 times daily. Very useful in Paralysis. Prescription No. 17. R Tinct. Arnica. Tinct. Capsicum, aaSi. Chloroform, pure, 3ii. Tinct. Sapo et Opii, 3ii. Mix: and mark external use. Excellent in Bruises and Sprains. Prescription No. 18. R Ungt. Belladonna, Si. Powd. Camp., 3i. Mix: Mark external use. In Painful Cords or Piles. Prescription No. 19. R Bromide Potassa, 3iii. Ciunamon Water, Si. Mix: Dose, a teaspoonful as occasion may require. Useful in Headache, or to produce Sleep. Prescription No. 20. R Infusion Buchu, 5 vii. Tinct. Buchu. Tinct. Cubebs, aa 3iv. Mix: Dose. 2 tablespoonfuls 3 t raes a day. Useful in Kidney Difficulties. Prescription No. 21. R Fresh Milk, Oss. Lime Water, 3 i. Mix: Four tablespoonfuls is a dose. Useful in Sour Stomach. Prescription No. 22. R Tinct. Spanish Flies, drops ii. Tinct. Henbane, lTlv. Water, 3x. Mix: *Dose,tablespoonful every 2 hours. Useful in Inability to hold Urine, or Paralysis of the Bladder. Prescription No. 23. R Tinct. Spanish Flies. Tinct. Camphor Comp., aa 3i. Tinct. Cinchona Comp., 3x. Mix: Dose, thirty drops, gradually in- creased to a teaspoonful, 3 times a day. Beneficial in Whooping Cough. Prescription No. 24. R Acet. Spanish Flies, Sss. Aqua Cologne, Si. Aqua Rosae, Si. Mix: Make a wash. Rub on the head when the hair falls out. Prescription No. 25. R Powd. Red Pepper, 3 ii. Boiling Water, Oss. Mix: Strain, and when cool take a tea- spoonful 3 times a day. Useful in Malignant Sore Throat. Prescription No. 26. R Elix.Peruvian Bark with Protox. Iron, Sxii. Dose, a dessert-spoonful after meals. An Agreeable Tonic. Prescription No. 27. R Liquid Acetate Ammon., 3ii. Sweet Spirits Nitre, 3 Hi. Aqua Camphor, 3ss. Syr. Simplex, 3iv. Mix: Dose, a teaspoonful every 3 hours. Very beneficial at the commencement of Fevers. PRESCRIPTIONS. Prescription No. 28. R Powd. Peruvian Bark. Powd. Rhubarb, Turkish, aaSss. Carbonate Magnesia, 9i. Conf'ect. Aromat. 9ss. No. 1. Cinnamon Water, Siss. Mix: Make a draught. To be taken twice a day. Excellent Cathartic. Prescription No. 29. R Sulphate Magnesia, 3ii. No. 2. Fluid Ext. Senna, 3vii. Simple Syrup, Sii. Mix: Take all at one draught. An Excellent Physic. Prescription No. 30. R Bals. Copaiba. Liquid Potassae, aa3iii. Mucil. Gum Arabic, Si. Peppermint Water, Svi. Mix: A tablespoonful before meals. Excellent in first stages of Gonorrhoea. Prescription No. 31. R Ammoniated Tartrate of Iron, 3i. Water, Svss. Simple Syrup, Sss. Mix: Dose, tablespoonful 3 times a day. Beneficial in Bright's Disease. Prescription No. 32. R Ext. Henbane, 3ss. Valerianate Ferri, 3i. Mix: Divide in 30 pills; dose, 1 after meals. Excellent in Neuralgia. Prescription No. 33. R Bromide Ferri, 3i. Syrup Orange, Sss. Orange Water, Siss. Mix: Dose, teaspoonful every 6 hours. Useful in Secondary Syphilis. Prescription No. 34. R Sulph. Ferri, Si. Distilled Water, 3xvi. Mix: Make wash, apply on linen every 2 or 3 hours. Excellent in Erysipelas. Prescription No. 35. R Powd. Galls, 3i. Sulphate Copper, Bi. Lard, 3i. Mix: Make ointment, apply to the- affected part 3 times a day. For Ringworm. Prescription No. 36. R Extract Gentian. Sesquicarbonate Ammonia aa3i. Mix: Divide into 30 pills; dose two, 2 or 3 times daily. In Obstinate Heartburn. Prescription No. 37. R Glycerine. Rose Water, aaSii. Powd. Borax, V)ii. Mix: Apply at bedtime. An excellent application for Chapped Hands, Chilblains, and Sore Nipples. Prescription No. 38. R Ext. Henbane. Camphor. Ext. Hops, aa, grs. iii. Mix: Make 2 pills; take at bedtime. In simple Wakefulness. Prescription No. 39. R Tinct. Iodine Comp , 3i. Make external use; apply with a brush thrice daily. Excellent Application to Swollen Joints. Prescription No. 40. R Powd. Peruvian Bark, Red. Si. Lard, 3ii. Mix: Make ointment; use 3 times a day on linpn. The best Salve for Sores and Ulcers. Prescription No. 41. R Powd. Dovers, grs. xl. Hyd. Sub. Murias., grs. viii. Mix: Divide into 8 powders; 1 in every 3 hours if awake. Excellent in Pneumonia or Lung Fever. Prescription No. 42. R Powd. Ipecac Root, grs.iv. Mucilage Gum Arabic. Simple Syrup, aa3ii. Distilled Water, 3i. Saltpetre, grs. xv. Mix: Two teaspoonsfuls every 4 hours. In Measles of Infants. Prescription No. 43. R Dover's Powd. Hyd. Cum Creta, aa grs.i. Mix: To be taken at bedtime. Excellent in the Diarrhoza of Teething Infants. Prescription No. 44. R Ground Flaxseed, Siv. Ground Poppy Flowers, Si. Mix: Divide in 8 poultices; use a fresh one morning and evening. Excellent Poultice for a Felon. PRESCRIPTIONS. Prescription No. 45. R Tinct. Lobelia, Sss. Orange Water, 3H. Distilled Water, 3iv. Dose, a tablespoonful 3 times a Mix day, Beneficial in Asthma. R Prescription No. 46. Carbonate Magnesia, 9i. Tinct. Cardamon Comp., 3ii. Orange Water, Sss. Syrup, 3ii. Mix: Dose, a teaspoonful frequently during the day. Excellent in Colic of Infants. Prescription No. 47. R Cod Liver Oil, Siv. Emulsion Almonds, Si. Whiskey, 3 ii. Mix: Dose, a tablespoonful after meals. Very Beneficial in Consumption. Prescription No. 48. R Sweet Oil, Sviii. Arom. Spts. Ammonia, 3ii. Mix: Dose, 3 teaspoonfuls night and morning. Good to Expel and Destroy Worms. Prescription No. 49. R Citrate Iron et Quinine, 3 Hi. Sherry Wine, 3 vii. Mix: Dose, a teaspoonful before meals. An Excellent Tonic. Prescription No. 50. R Tinct. Peruvian Bark. Tinct. Gentian. Tinct. Cardamon, aaji. Essence Checkerberry, gtts.xxx. Mix: Dose, a teaspoonful before meals. Excellent in a Capricious Appetite. Prescription No. 51. R Wine of Ipecac, Si. Dose, a teaspoonful to children in con- vulsions. This is an invaluable rem- edy, and always safe to administer, care being taken not to strangulate the patient from inability to swallow. The reader must bear in mind that the use of the foregoing remedies is only for adults, and that the author has purposely refrained from giving any formulas for the diseases mentioned chiefly in this treatise, from the fact that nervous diseases are the most insidious, painful, and destructive that afflict the popula- tion of the earth, and the remedies therefore are most potential, and might Eroperly be classed as edge-tools in ,medicine. Apropos to this subject, I would ere quote the statement of the eminent Professor of Anatomy and Physiology at Harvard Medical College to the Fellows of the Massachusetts Medical Society, "that medicine as they practised it (that is, the physicians in general or family practice) did more harm than good; and if all the drugs they used were thrown into the sea, it would be all the better for their patients, but all the worse for the fishes." From the daily observations of the author he can fully corroborate the sentiments of this outspoken, truthful, and learned gentleman. Myriads of broken-down, wretched invalids are constantly crowding upon his attention, whose misery and wretchedness are owing whoily or in part to the ignorance of previous medical advisers, and he feels constrained to admonish invalids of this class to confide the treatment of their case to none except those who devote their whole energy and abilities to the treatment of nervous diseases, and who give undoubted evidence of their superior qualifications. CONTENTS. Chapter. Page. I. The Nerves and the Brain......1 II. Nervous Disorders and the Temperaments . . . 11 III. A Chief Cause of Nervous Derangement ... 24 IV. Patients with the Nervous Temperament ... 31 V. Convivial Habits and Nervousness .... 39 VI. Anxiety of Mind ........ 43 VII. Nervousness and Religious Excitement . . . 48 VIII. Illusions and Hallucinations......52 IX. Sleep and Sleeplessness .......66 X. Epilepsy..........74 XL The Suicidal Propensity.......78 XII. Treatment of the Insane.......89 XIII. Urinary Analysis, as a Detective of Disease . . 101 XIV. Various Urinary Deposits......114 XV. Pathology of the Nerves and Nervous Maladies . 124 XVI. A Few Hygienic Observations on Nervous Affections 132 XVII. A Curious Case of Supposed Demoniacal Possession . 140 XVIII. Hope and Confidence as Therapeutic Agents . . 146 XIX. Alcohol, Tobacco, Opium, Hacshish . . . .150 XX. Body vs. Mind.........158 XXI. General Paralysis........167 XXII. Dipsomania, or Drunken Insanity.....178 XXIII. Late Suppers and Dreams......1S3 XXIV. The Uses and Abuses of the Popular Nervines . . 189 » THE NERVES AND THE BRAIN. CHAPTER I. INTRODUCTORY AND GENERAL REMARKS. The barbarian, and the rude, ignorant European peasant, scarcely know that they have nerves. But civilization, cul- ture, and refined artificial modes of life bring the nerves into almost fearful prominence. Few who live in cities, or come in any way within the vortex of our social life, have escaped occasional attacks of nervousness.* Is nervousness, then, asks a distinguished English writer on the physiology and pathology of the nerves, an inevitable condition of civiliza- tion, a tax we must be content to pay for our advantages ; or can we free ourselves from its assaults without paying too great a price for the immunity ? What is the malady and its cause, that we may know what the cure must be? And, first, have the nerves really anything to do with it, or have they borne the blame while other portions of our organiza- tion have been at fault? When we are in that excitable, tremulous condition, in which there is a morbid anxiety to labor, with diminished power of performance ; when, without any definite ailment, wrc seem deadened in every faculty, while yet the least vexation is felt as an intolerable annoyance, — are we right in saying that it is especially the nervous * Vide Ilinton's works, whose admirable account of the nervous system has been summarized in the following chapter, — our limits forbidding extended and scientific details, which are always tedious and often unin- telligible to the general reader, for whom we write. 2 THE NERVES AND THE BRAIN. system that breaks down? In order to answer this question, we must get some definite idea of that complex machine, the Nervous System, as it exists in man. Beautiful and myste- rious as are its operations and results, its mode of action has been well ascertained, and is exceedingly simple. The ner- vous system is one of the chief characteristics of animal life, especially of the higher animals. By its means the various organs, which make up the body of an animal, arc blended into a whole; and thus the animal is a unit or individual, while the plant always remains a mere bundle of more or less similar parts. Through the nerves the body is acted upon by, and can react upon, objects that affect it from without, not only by a motion of the part immediately affected, but by the combined movement of many, and, it may be, distant organs. In this lies the primary need of a nervous system. It is in its sim- plest aspect merely a channel by which the affections of one portion of the body are enabled to call out the activity of another. Keeping this idea in mind, we shall find there is no difficulty in following, in their general principles, the structure or functions of the nervous system, even in its most highly developed and complicated forms. If we look at the human brain, we find that it consists mainly of a vast mass of fibres. Their number, tenuity, and variety of direc- tion are so great that no skill has hitherto availed to trace them in detail, though their course has been pretty gener- ally well made out. Emanating from the brain and spinal cord, long lines of fibres pass to each region of the body, and distribute themselves in a minute net-work, that, if we could see it by itself, would appear before us a perfect image of the body, all pure nerve. The fibres which constitute the chief mass of the nervous system are simple in their struc- ture, so far as the microscope can reveal it, and present a very curious analogy to a telegraphic ware. Like the latter, INTRODUCTORY. 3 each nervous fibre consists of a small central thread (or tube, perhaps, in the case of the nerve, though the tubular structure cannot be demonstrated), surrounded by a layer of a different substance. The central thread (or axis) is of a grayish color; the surrounding material is of a glassy appearance, soon becoming an opaque white after death, and giving then the characteristic white appearance to the nerves. The fibre, consisting of these two portions, is included in a sheath, which isolates it. If we roll up a wax candle in paper, that will give us a rough illustration of the nerve fibre. The paper is the external " sheath " ; the wrax is the intermediate white matter; the wick is the central axis. It is most natural to believe that the analogy suggested by this structure is a true one, and that the white substance acts the part of the gutta-percha round the electric wire, as an insu- lating medium for the currents which travel along the cen- tral portion. But this is not proved. Probably, owing to the minuteness of the parts, it is beyond the possibility of experimental proof. For in man two or three thousand of these fibres would occupy but an inch in their largest part. There is another kind of nervous matter, besides the fibres, and that consists of cells. The nerve fibres spmetimes run into them; sometimes they pass among them without ap- pearing to communicate. Cells of this kind form a thin layer over the surface of the brain, and its fibres for the most part have their origin from or among them. They also exist in large numbers in certain spots in the substance of the brain, and they are found within the spinal cord in its whole length. Wherever they are found they go by the name of gray matter, the nerve fibres being called the white matter. The fibres which constitute the nerves, strictly so called, are conductors, and they conduct to and from the cells. What, then, is the part played by the latter? But before answering this question, it is worth while to peruse 4 THE NERVES AND THE BRAIN. and note the extreme simplicity of form exhibited by this element of the nervous system. In the gray matter of the brain, wre have arrived at the very highest organic structure, the great achievement of the vital force, the texture in which bodily life culminates, and for the sake of which, we might almost say, all the other organs exist. And we find a structure of the very lowest form. Mere cells and granules —Nature's first and roughest work, her very starting-point in the organic kingdom — strewn in a mere mass, with no appreciable order, over the ends of a multitude of fibres, and loosely folded up, as it seems, for convenient storage ! This is what meets the eye. Is this the laboratory of reason, the birthplace of thought, the home of genius and imagination, the palace of the soul? Nay, is this even the source and spring of bodily order, the seat of government and control for the disorderly rabble of the muscles? Should we not have expected, when we came thus to the inmost shrine of life, and penetrated to the council-chamber of the mind, to find all that had before appeared of skilful architecture and elaborate machinery surpassed and thrown into the shade? But it is all cast away. Mechanical contrivances for mechanical effects ! Skil- ful grouping and complex organization there may be for the hand, eye, the tongue; for all parts and every function where the mind is not. But where the spirit comes, take all that scaffolding away ! The gray matter of the brain is very abundantly supplied with blood. What is the office of the cells or gray matter ? The spinal cord of man is a series of groups of cells, giving off nerves on each side, and connected by communicating fibres with each other, and with the larger groups in the brain, which also give off nerves to the nose and eye, the skin and muscles of the face, and other parts. Thus, in man and all animals alike, masses of gray matter the cells, are placed at the centre, and nerve fibres connect them with the organs of the body. It has been proved also INTRODUCTORY. 5 by the beautiful experiments of Sir Charles Bell that the nerve fibres are of two kinds : some conveying an influence from the organs to the centres, where the nerve cells are placed ; and others carrying back an influence from them to the organs. So these groups of cells evidently answer to the stations of the electric telegraph. They are the points at which the messages are received from one line and passed on along another. They are called ganglia in scientific lan- guage. But besides this the cells are the generators of the nervous power. For the living telegraph flashes along its wrires not only messages, but the force also which ensures them fulfilment. A nerve bears inward, say from the hand or foot, an impression, it may be of the slightest kind; but the cells are thrown into active change by this slight stimu- lus, and are thus able to send out a force along the nerves leading to large groups of muscles, and excite them all to vigorous motion. In the above we have merely aimed at giving a general account of the Nervous System. The nerves are the special vehicles of will and feeling, hence their derangement is most calamitous. By them we see, taste, smell, hear, and feel. By them we command our limbs with the aid of the muscles. Hence the terrible character of nervous disease and derange- ment, which strikes at the very source of all our pleasurable activity, enjoyment, and conscious life. Diseases of the brain, of the spinal cord, of the nerve cells and of the facial nerves, and cerebro-spinal disease, compose in general terms the terrible bead-roll of nervous disorders. Under these heads come insanity, softening of the brain, epilepsy, hydro- phobia, all kinds of paralysis, neuralgia ; in short, all morbid affections, which are specially characterized by pain and dethronement of the mind. Fortunately for suffering hu- manity, Dr. Hammond, in his great work on Diseases of the JScivous System, is strictly correct when he says, that " in no 6 THE NERVES AND THE BRAIN. department of medical science has progress been more de- cided during the last decade, than in nervous affections." The writer of this treatise, with a most ample and gratifying experience in the treatment and cure of nervous disorders, is able fully to indorse the above assertion. Whether or not he himself has in his professional career contributed to this progress in the means of ameliorating the acutest human suffering, it is for his multitudinous patients to say. At any rate, he is willing to abide by their verdict. Derangements of the nervous system are seen in the par- oxysms of asthma and the seizures of epilepsy, in both of which affections the muscles are thrown into excessive con- traction through a morbid condition of the spinal cord. Of a different order are the languor and feeling of utter disa- bility for muscular exertion which creep over us at times. These feelings show that the nerve centres which preside over muscular exertion have become oppressed and sluggish, likely enough through want of proper exercise. Of a differ- ent kind, again, are tremblings of the muscles, or involuntary jerks and twitchings, and, in brief, all that condition known by the expressive name of "fidgets." What is the source of this irritability, which renders it impossible to keep the muscles still? We can answer in general that irritability means weakness. A physician of eminence compares it to the whirling motion of the hands of a watch of Avhich the mainspring is broken. In our physical, as in our moral nature, strength is calm, patient, orderly ; weakness hurries, cannot be at rest, attempts too much. Strength in the living body is maintained by the full but natural exercise of each organ. The full access of all healthful stimuli to the skin, and through it to the nerves of sensation, is the first and chief condition of the healthful vigor of the nervous system. Among these invigorating influences, fresh air and puie INTRODUCTORY. 7 water hold the first place. The great and even wonderful advantages of cleanliness are partly referable to a skin healthily active, open to all the natural stimuli, and free from morbid irritation upon the nerve centres of which it is the appointed excitant. The state of general vigor which wre call " Tone " also depends upon the healthy action of these nervous centres. It consists in an habitual moderate contraction of the mus- cles, due to a constant stimulus exerted upon them by the spinal cord, and is valuable less for itself than as a sign of a sound nervous balance. Tone is maintained, partly by healthful impressions radiated upon the spinal cord, through the nerves from all parts of the body, and partly by the stimulus poured down upon it from the brain. So it is dis- turbed by whatever conveys irritating or depressing influ- ences in either direction. A single injudicious meal, a single sleepless night, a single passion or piece of bad news, will destroy it. On the other hand, a vivid hope, a cheerful resolve, an absorbing interest, will restore it as if by magic. For in man these lower officers in the nervous hierarchy draw their very breath according to the bidding of the higher powers. A chief condition of keeping the nerves and brain healthy is to keep them in full vigor and in natural alternations of activity and repose. Muscular exercise has a most bene- ficial effect on a depressed or irritable state of mind. The bodily movement, by affording an outlet to the activity of the spinal cord, withdraws a source of irritation from the brain, or it may relieve excitement of that organ by'carrying off its energy into a safe channel. We see evidence of the same law in the delightful effect of a cheerful walk, and in the demand for violent exertion, which is so frequent in insanity. The power of the brain over the vital condition of the body is exerted through a 0 THE NERVES AND THE BRAIN. . particular set of nerves, which have been called "the sympa- thetic system." They are somewhat smaller and simpler than the nerves of sensation and motion, with which, how- ever, they are intimately connected. They are distributed to the organs on which life depends (the lungs, heart, stom- ach, etc.), and to the blood-vessels all over the body. Thus the condition of the brain is necessarily the key to that of the wrhole body, and its influence is universally paramount, both directly by its power over the heart and breathing, and still more profoundly by its indirect control over the supply of blood. There is no mystery on the effects produced on health by excess of mental labor, or by long-continued cares, nor in the bodily torpor which attends a merely inactive mind. " Nervousness" naturally results from an overtaxed brain. The wonder is, not that it occurs so often, but that, amid the rude shock to which our life is subject, it is not more fre- quently experienced. If we would have our bodies healthy, our brains must be used, and used in orderly and vigorous ways. The torpid, unhealthy frame and languid circulation of the idiot are but an exaggerated instance of the unnat- ural torpor to* which he condemns himself, who wastes his life in indolence, or consumes it in dissipation. To him Nature, indeed, has been kinder than she has to the idiot — he does but abuse her bounty to become a worse enemy to himself. The perfect health of a man is not the same as that of an ox or horse. The preponderating capacity of his nervous part demands a corresponding life. But the very causes which make the proper exercise of the brain especially needful, render its excess especially baneful. The sicns of this excess, or excess combined with misdirection me t us on all hands: in weariness, despondency, disgust or causeless anger; in racking neuralgic pains, or o-radual INTRODUCTORY. 9, decay of vital power, or in the insidious threatenings of serious disease. How could these results be guarded against, we ask. The answer can be but one. Health can no more be obtained without its price than anything else. Nature has forever forbidden it. The flame of life can neither be fed nor renewed with stolen fire. The condition of rescue from overwork is rest and change, — fresh air, and the soothing influence of natural scenery, if they can be obtained. One word, before closing these somewhat general intro- ductory remarks, on the subject of cities, as our modern life is more and more concentrated in cities, which develop and intensify the nervous energy wonderfully, and by their man- ifold and constant excitements fearfully multiply nervous disease in all its forms. A distinguished author observes, that " the invention of towns were a pure gain to humanity, if due admixture of the country life can bo secured." And to obtain this advantage for our laboring populations is one of the great tasks of our age, and one of the great problems for managers of railroad corporations in particular. Our physi- ology teaches us that the vice and misery of our great towns can never be successfully combated in the strongholds which they have made their own, and fortified for generations,—the courts and alleys where the poisonous atmosphere combines with all hateful sights and sounds at once to deaden and irritate the nervous sensibility. From the continued breath- ing of a vitiated atmosphere inevitably arises either apathy or a craving for intoxicating drinks ; in all probability, each in turn. On the other hand, the splendor and allurements of city life constantly acting upon the senses, especially of the young and susceptible, ar3 calculated to produce nervous derangement, and prematurely use up those exposed to them. Indeed, modern civilization, with its splendid material tri- 10 THE NERVES AND THE BRAIN. *umphs and manifold devices for comfort, luxury, and sen- sual enjoyment, grows ever more and more trying to the nerves, and has rendered completely unfashionable the plain, frugal, ascetic life of our ancestors. Hence it is that the medical practitioner, who contributes by his skill and inge- nuity to restore a jaded and disordered nervous system, and check the spread of nervous affections, is emphatically a Public Benefactor. CHAPTER II. NERVOUS DISORDER AND THE TEMPERAMENTS. A careful examination of numerous cases of nervous dis- order has satisfied me that the study of the temperaments is absolutely necessary on the part of the physician who aims at even ordinary success in the treatment of disease. For instance, were we to treat four different persons, all suffering alike from the same nervous disorder, but all of them having different temperaments, writh precisely the same remedies, without taking into account the peculiarities of each, or the effect of these upon the constitution, as well as the nature of the disease,— we should be as little likely to succeed in effect- ing a cure as would the mariner in reaching his destination, who steered in a direct right line by compass for the point which he wished to reach, totally regardless of, nor making the slightest allowance for, leeway, current, or any other disturb- ing causes. It is therefore as indispensably necessary that the physician take into account, not merely the general nature and character of the disease, but also the various concomi- tant circumstances, before he incur either risk or responsibil- ity. It is the study of these circumstances, and the paying due attention to them, that constitute the accomplished and trustworthy physician; and those traits alone can ensure him success in practice. In the study of all disorders, we must take into account and carefully review both the history 12 NKRVOUS DISORDER AND THE TEMPERAMENTS. of the disease and the history of the case. The first makes us acquainted with all the general phenomena and tendencies of the disorder, while the second brings us into relation with all those specialties which require peculiar modifications of treatment. In the Nervous Temperament we find that the brain is large and well developed, and its energies and those of the nervous system are the most predominant, and take the lead over those of all the other organs. The features are Fig. 1. Nervous Temperament. sharp and prominent, the eye large and expressive • the mouth betokens intelligence, and frequently there is a full and intellectual forehead; the skin thin and transparent with flossy, silky hair; the muscles small but well marked with quick and active motions; the face generally pale, and frequently expressive of anxiety ; the brain and whole of the nervous system in a high state of activity. Such persons are for the most part quick and intelligent, and highly sensitive NERVOUS DISORDER AND THE TEMPERAMENTS. 13 to every kind of impression; and they are readily excited and easily depressed. At one time you may find them en- joying themselves to the fullest extent, and in a very short time after, perhaps in tears. The dispositions of persons in whom this temperament predominates, arc much modified by the circumstances in which they may happen to be placed. Confinement, especially if the occupation be sedentary, never fails to produce evil effects upon the constitution. Individ- uals of this temperament arc highly sensitive to all those agents which act upon the nervous sj^stem. Such persons require to be treated writh great care and delicacy. Fig. 2. Lymphatic Temperament. But in the Lymphatic Temperament, in which the abdomen is remarkably large and prominent; the brain dull and in- active ; the body round and soft; action slow and heavy ; skin muddy and flabby ; circulation weak and languid; mus- cles soft, flaccid, and feeble, with great aversion to either 14 NERVOUS DISORDER AND THE TEMPERAMENTS. mental or bodily exercise, — we find the energies of ever}' kind Arcry feeble, indeed almost dormant. Thus we see that persons of this temperament differ materially in these particulars from persons of the former. Indeed, so little excitable are people of the purely lymphatic tempera- ment, that it is not without the greatest difficulty they can be aroused, or induced to exert themselves in the smallest degree, while they are quickly exhausted when aroused to exertion. It is obvious that this inert temperament is not so liable to nervous derangement as the former, and when thus disordered, that it does not require the same delicate treatment as the other. Persons of the Sanguineous Temperament differ widely Fig. 3. Sanguineous Temperament. from those of the Lymphatic. In the former, the luno-s and heart are large, and the power of the latter oro-an is con- NERVOUS DISORDER AND THE TEMPERAMENTS. 15 spicuous, predominating over all other systems. The pulse is strong and regular; the veins turgid, full, and blue; the chest large ; the complexion fair and florid ; muscles firm; hair reddish, chestnut, or auburn. Impressions made on the nervous system are vivid; imagination luxuriant; temper passionate, but not vindictive ; and individuals of this class, though readily excited, are still easily appeased. Now were we to treat a patient of the sanguineous temperament, in the same wray that we should treat one of the lymphatic, suffering from the same disease under exactly similar circumstances, the consequences would be most deplorable. For instance, wine, spirits, and such stimulants would be wholly inadmis- sible in treating a patient of the sanguineous temperament, because in such an one the heart and arteries are already too prone to over-action. The use of stimulants by a patient of sanguineous temperament would almost to a certainty bring on inflammation ; or wre should by such means incur the risk of doing some violent injury to the heart or some other part of the nervous system. The Biliary Temperament, again, differs from the fore- going, thus briefly noticed. In persons of this tempera- ment, the liver is large, and its functions are readily called into activity, and there is a great tendency to a redundant secretion of bile. The pulse is stronger and more frequent than in the purely sanguineous; the veins are prominent, the sensibility acute, and there is great constitutional energy. The skin is generally dark or sallow, with occasionally a yellow tinge; hair black or dark brown, and often short and crisp ; the muscles firm, and well devel- oped ; temper abrupt, but not liable to such extremes of excitement as in those of the purely nervous ; the concep- tions are bold, while they themselves are inflexible in the pursuit of a project, nor are they so readily exhausted as persons of the nervous or other temperaments. In attaining 16 NERVOUS DISORDER AND THE TEMPERAMENTS. the object they wish, individuals of this temperament are dauntless and persevering to the last. In treating persons of biliary temperament, suffering from nervous affections, Fig. 4. Biliary Temperament. and m wnom the secretion of bile is somehow faulty, we must not turn our attention exclusively to the con- dition of the stomach and bowels, as the only cause of such disorders. It is true that too much food, or food of an indigestible nature, taken into the stomach may affect the liver, derange its functions, and so vitiate its secretion, and thus bring on a train of nervous symptoms. Still, such are not the sole causes of deranged bile ; and as the morbid effects cannot be relieved till we have ascertained and re- moved the cause, we must endeavor to discover this by inquiring most minutely into the history and all the circum- stances of the case as already explained. NERVOUS DISORDER AND THE TEMPERAMENTS. 17 The various passions, whether of a depressing or exhilarat- ing character, have great influence in inducing nervous dis- order. Sudden emotions, too, have the same effect; and the more sudden and violent, the greater their pernicious effects, not only upon the system at large, but upon the ner- vous portion in particular, — ranging from mere temporary trepidation or excitement, to the most inveterate mania or confirmed insanity. Thus jealousy, abused confidence, fear, sudden alarm, prolonged or continued apprehension, anxiety, grief, joy, unexpected good fortune, and similar emotions, exert, very frequently, a most dangerous influence. Such effects will violent emotions of this kind produce upon the nervous system, that the functions of different and distant parts become not only sensibly, but deeply implicated. Thus very strong impressions upon the mind with the concomitant conflict in the nervous system have so acted, even upon young persons, as to turn the hair gray in a single night; while in other cases the skin, instead of exuding the ordinary perspiration, has sweated blood. These results sometimes supervene so rapidly, and come on so, suddenly, as to wholly exempt them from any interference, and place them beyond all possible attempts at prevention or ar- rest. I am frequently called upon to prescribe for patients of biliary temperament suffering severely from nervous dis- order, which I have traced to deranged state of the stomach and bowels ; and these conditions were clearly referable to the abuse of purgative and mercurial medicines. Costive- ness by no means invariably indicates the necessity of re- course to opening or purgative medicines. Many persons live almost entirely upon food, nearly the whole of which is not only convertible, but actually converted into nutriment and completely assimilated, thus leaving little, or rather no residue, to pass off through the bowels. If, then, in such 2 18 NERVOUS DISORDER AXD THE TEMPERAMENTS. circumstances, it should be deemed advisable to move the bowels, the more rational plan wTould be to alter the nature of the diet, and substitute more of a vegetable, while we reduce in a corresponding degree the amount of the more concentrated and nutritious food. Vegetables contain less of the nutrient principles, and consequently leave a larger amount of residue, upon the expulsion of which superfluous material the action of the bowels may be more naturally and far more legitimately and advantageously employed, than in responding to the irritating influence of drastic purgatives. "It is in cases of this description," says Cowle, in his excel- lent work on the Physiology of Digestion, "that the physi- cian is more frequently consulted, and that he has the best opportunity of showing his discrimination and judgment. If he and the patient are satisfied with simply procuring relief, he has ready means at hand in any of the ordinary purgatives ; but if a cure is their object, they must go back to the root of the evil, and begin by restoring the digestive organs to health." Nervous disorder in biliary temperament is clearly traceable to the secretion of bile being vitiated or otherwise deranged. In laying down plans for locating such affections, wre must not only determine their nature, but inquire into and ascertain the cause, and remove this if pos- sible. If, for example, we should find, upon careful exam- ination, irregularity in diet to be the fundamental cause of the evil, which is frequently the case, we should most per- emptorily interdict all those kinds of food which either expe- rience or science has taught us tend to vitiate or derange the secretion of bile; such, for instance, as a too free use of porter, sugar, cream, butter, rich, fatty meats, ardent spirits wine, etc. These, it is well known, and chemistry confirms our experience, increase the quantity of bile to an amount far beyond what is required for the purposes of healthy NERVOUS DISORDER AND THE TEMPERAMENTS. 19 digestion; and, further, the most moderate experience has repeatedly shown that the superfluity often lays the foun- dation of some nervous disorder. I have also had many opportunities of witnessing the ill effects, on particular cases, of meat suppers taken late at night. This proves very injurious to persons of biliary tem- perament, by the formation of a large quantity of bile during the night, the individual frequently sleeping in a close, con- fined, ill-ventilated chamber, while at the same time respira- tory and circulating processes are slow and inactive. The quantity of oxygen necessary to enable the lungs to burn off the carbon being withheld through impurity and a defi- cient supply of air, as well as from other causes, the liver is called upon to assist in secreting the superfluous carbon under the form of bile. The person in consequence awakes stupid, unrefreshed, and for the most part with^a bad, oppressive headache. Indeed, so liable are biliary persons suffering from this form of nervous disorder to the consequences above stated, that I have repeatedly seen a severe attack of head- ache brought on by the patient retiring to repose in an ill- ventilated apartment, after taking a full meal. As a means of immediate relief under such circumstances, a saline purge is one of the most effectual, as it will drain the liver of its redundant bile, and thus afford instantaneous, but still only temporary relief. Permanent benefit must be sought for in avoiding the exciting cause, by the inhalation of pure, fresh air, friction and cleanliness of the skin,, and warm bathing, which will facilitate the exit of carbon and other impurities through the other channels, the lungs and skin. By such means, and avoiding late suppers, the liver will be relieved from the necessity of over-activity, and of forming a super- fluous quantity of bile ; and thus, the real cause of the dis- order bein^ removed, the morbid effects will naturally cease. Another fertile source of nervous diseases in bilious tern- 20 NERVOUS DISORDER AND THE TEMPERAMENTS. peraments, which formerly came under my observation more than at present, was the taking large quantities of Cod Liver Oil. It is well, before we indiscriminately prescribe fashionable remedies, to consider how they are likely to act. The Laplander, dwelling in the arctic regions, where it is intensely cold, and the atmosphere in an equal bulk contains a large quantity of oxygen, lives principally upon carbona- ceous substances, as train oil, blubber, and fat. But the Indian, who lives in the torrid zone, "where the atmosphere is rarefied, and for equal bulk contains but little oxygen, selects rice, vegetables, and other diet containing but little carbon, and it is found that such are best suited to the cir- cumstances under which he lives. For the same reason, Cod Liver Oil administered in summer, when it is hot and oppressive, more especially if given to a patient of a biliary temperament, will seldom fail to aggravate the disease it was given to cure. Nature evidently intended that the liver should free the blood from those principles which form the radical or constituents of the bile, and apply them, so elimi- nated, to perfect or complete the function of digestion. But if more bile is formed than is necessary to this end, the excess acts as an irritant to the bowels, and occasions what is com- monly called "bilious diarrhoea." If, however, on the other hand, the bile be scanty in quantity, as often occurs with persons who have resided long in tropical climates ; or suf- fered frequently and severely from agues; or who have indulged to a pernicious extent in a too free use of alcoholic liquors, in consequence of which the liver pours out fibrin which, acting as a ligature upon the portal vessels, impedes the flow of bile, —the consequence is that the bowels become constipated ; the stools clay-colored ; the powers of digestion greatly weakened, and otherwise impaired, attended with great loss of strength and flesh. The skin becomes rouo-h hard, and dry; the countenance assumes a sallow aspect, or NERVOUS DISORDER AND THE TEMPERAMENTS. 21 a general yellowness pervades the skin, and true or confirmed jaundice is the result. This is not unfrequently attended with the formation of gall-stones, which greatly aggravates the evil, and leads to very unfortunate consequences, an instance of which, of remarkable severity, lately fell under Fig. 5. my observation. In this case, upon dissection after death, the gall-bladder felt like an uniformly hard, solid mass, giv- ing the impression that its cavity was wholly occupied by a single calculus. Upon opening it, however, the cavity was found filled with a number of distinct small calculi, the sur- faces so moulded and fitted to each other as to appear to the touch a single solid mass. The appearance of the gall-blad- der (in this case) laid open and the calculi exposed is well shown in Figure 5. This patient used to suffer, at intervals, the most excruciating pain; especially during the passage of gall-stones into the intestines, which occasionally took place, and was usually attended with jaundice and other hepatic disorders. In such cases, strict attention to regimen and diet should 22 NERVOUS DISORDER AND THE TEMPERAMENTS. be enjoined; the food should be light but nutritious ; the patient should abstain from all rich and fat meats, pastry, doughy puddings, and, as far as possible, from spirituous and fermented liquors. By carefully observing and abiding by these rules, a person may live for many years, though he may have but little liver remaining. But if persons afflicted with serious disease of the liver will still persist in indulging in the pleasures of the table, and will continue to violate those rules laid down for their guidance, they will speedily bring existence to an end, and perish in the extreme of ema- ciation and misery. A gentleman consulted me four years ago, suffering very severely from an affection of the liver, and for which, for sev- eral years, he had been taking almost every kind of medicine, without much benefit. I had every reason to believe that the patient would never perfectly regain his health ; yet I felt sure that much relief might be derived from the proper use of warm baths with dry cupping, and the external use of nitro-muriatic acid; frictions to excite the skin : light, nutritious, unirritat- ing diet; the occasional use of a pill composed of aloes and rhubarb; horse exercise ; and a residence in a dry pure air, — were the means which seemed best suited to prolong life. He pursued the proposed plan for about five months ; and in a note which I received from him, in the interval, he states : " The action of my bowels is now regular and nearly natural and I very rarely experience the sickness after food; I solution in spirit, is here subjoined — is a urinary principle, Figure 12. excess or deficiency of Avhich in the urine is often connected with important nervous disorders. When urea is in excess, it often causes a great deal of irritation; there is a dull, heavy, dragging pain in the lower part of the back, Avhich is much increased by exertion. A very constant symptom, more especially in certain forms of excess of urea, is a frequent voiding of the urine. There is often a greater quantity voided than is consistent Avith health; but from the frequent calls, the quantity passed seems to the patient greatly to 116 VARIOUS URINARY DEPOSITS. exceed Avhat is natural. Hence this affection is, and has often been, confounded with diabetes, a disease of a very different nature. In speaking of the treatment of this affection, Dr. Prout very justly obserAres, and in practice I find his ArieAvs con- firmed, "That calomel, black doses, and saline purgatives are calculated to do infinite mischief, and will probably render a manageable disease perfectly unmanageable,"—hence the necessity of at once ascertaining the true nature of the dis- order. A patient lately consulted me, whose urine had for some time contained an excess of urea. He had been taking cal- © Figure 13. omel, Avhich, however, had not relieved him, and he Avas rec- ommended the daily use of fluid magnesia. Upon examining the urine under the microscope, I discov- ered crystals in beautiful tufts, which Avere at once copied by the artist, and the delineations (Fig. 13) are here subjoined Upon further inquiry, I found them to consist of urate of magnesia. This patient Avas much relieved by discontinuing the medicine,—paying strict attention to diet, and takino- small doses of oxide of silver. VARIOUS URINARY DEPOSITS. H< In certain forms of degeneration of the kidney — granular, for instance — the serum of the blood passes off by the kid- neys. Such urine is albuminous, coagulating by heat, more especially if a feAv drops of nitric acid be added. When albuminous urine depends upon granular kidney, it may be regarded as a fatal symptom. We must, hoAvever, be cau- tious in pronouncing such an unfavorable opinion. Not very long since I Avas called upon to visit a gentleman Avho Avas studying for the bar. For some time he had been suffering from scArerc nervous, aching pain in the back and loins. A medical gentleman, a friend of his, having discovered albu- men in the urine, pronounced him suffering from organic dis- ease of the kidneys. His friends became greatly alarmed, especially Avhen informed that nothing could be done to save the patient. At this juncture I saAV the case. The general appearance Avas not such as to excite in my mind the notion of organic disease. All those symptoms, — the swollen face and eyelids, the harsh, dry state of skin, the dull, stupid look and tendency to droAVsiness, —Avere not present in the slightest degree, nor Avas there the least indi- cation of any tendency to dropsy. I Avas, in consequence, induced to doubt that the kidneys had anything to do Avith the diseased condition of the urine. I therefore Avashed out the bladder Avith distilled Avater, by means of a double catheter; and then made him drink, in my presence, tAVo or three tumblers of filtered Avater. He Avas placed, on his bare feet, upon a cold marble slab, and in less than ten min- utes passed a considerable quantity of urine, Avhich, on ex- amination, afforded not a trace of albumen. This sufficiently proved that the kidneys Avere not the source of the albumen. Upon stricter inquiry it Avas found that the albumen Avas de- rived from the mucous coat of the bladder. It disappeared very shortly under the influence of the tincture of sesqui- chloride of iron, iu doses of tAvcnty drops three times a day. 118 VARIOUS URINARY DEPOSITS. I mention this case to show the necessity of caution, and the inconvenience Avhich may result from inferring degeneration of the kidneys merely because of a little albumen in the urine. Lithic or uric acid, of Avhich there is a diagram (Fig. 14) attached, is likewise a principle by Avhich the urine is des- tined to carry out certain effete matters from the system. It howTcver sometimes happens that more lithic acid is formed than is evacuated with the urine. The superabundance Figure 14. either is retained in the kidney, giving rise to the formation of renal calculi, or it remains in the blood, and occasions various forms of nervous disorder. It is Avell knoAvn that in rheumatism the blood comparatively abounds in lithic acid. Occasionally this acid, after remaining for some time in the kidney, passes into and remains in the bladder, form- ing a nucleus for further deposition, and vesical calculus is the result. One of my patients requested my attention to a poor man, a shoemaker, Avho had been suffering for thirteen years from a nervous affection, Avhich latterly had increased so much, and occasioned so great a degree of distress, that he could VARIOUS URINARY DEPOSITS. 119 hardly attend to his Avork. He had tried a variety of reme- dies, and consulted numerous practitioners, and various vieAvs Avere taken of the nature of the case. Having obtained several specimens of the urine, I found, upon examination, that it abounded in lithic acid, which Avas deposited in the crystalline form. The appearance of the acid, Avith the general circumstances of the case, induced me to suspect the existence of stone in the bladder, as the cause of the nervous symptoms from which he suffered. He came to Boston, and, on sounding, the existence of calculus was clearly and decidedly proved. There Avere a great number of very small calculi of the lithic kind, many of Avhich I succeeded in crushing. lie became impatient, hoAvever, it being inconvenient to him to be so much in Boston. He therefore determined upon going into the Boston Hospital to be cut for stone. The opera- tion Avas very skilfully performed, and the stones adroitly extracted from the bladder; but inflammation set in on the third day, of which the patient unfortunately died. When lithic acid deposits in the joints in the form named "chalk stones," there is much nervous irritation set up in the system; and patients of this class suffer so much from ner- vous derangement, that the most trifling incidents Avill throw them into a nervous paroxysm. These gouty concretions do not consist of chalk, but of urate of soda; and the diagram (Fig. 15) sIioavs the form of crystallization assumed by the uric acid Avhen liberated from its combination with the soda. When the lithic acid diathesis preArails, the digestive func- tions arc usually much out of order, and the patient complains of flatulence and great acidity of stomach, much increased by acescent fruits and vegetables, and indulgence in port wine. It is of the utmost importance that such derangements of the system should be speedily recognized. A few grains of 120 VARIOUS URINARY DEPOSITS. carbonate of potass taken three or four hours after dinner, and perseA'ered in for a short time, will remove a great deal Figure 15. of mischief, and prevent the formation of stone in the bladder, which cost the patient, Avhose case I have just mentioned, his life. Cystine, or Cystic oxide (see diagram, Fig. 16), is very Figure 16. rare, but Avhen it occurs is attended with severe nervous derangement. It Avas first described by Dr. Wollaston, and VARIOUS URINARY DEPOSITS. 121 afterwards by Marcet; and a very excellent account of the substance itself, and of the state of the urine in which cystine prevails, Avas published by my friend, Dr. Venables, some years ago, in the " American Journal of Medicine." Little or nothing has been added to Dr. Venables' excellent detail. Liebig has lately announced the existence of hippuric acid (Fig. 17), as a constituent of human urine. It is occa- Figure 17. sionally present in quantity in the urine of hysterical and nervous females, and in the urine of persons who have been compelled to live for some time upon a poor, low, and bad diet. Change of air, and good nutritious food, with tran- quillity of mind, will be found among the most effectual rem- edies. The earthy phosphates are constantly deposited from the urine of nervous patients, and many of the symptoms in such cases, are analogous to those Avhich occur in the lithic acid diathesis. The triple or ammonio-magnesian phosphate is delineated in Fig. 18. The deposition of the prismatic phosphate is generally 122 VARIOUS URINARY DEPOSITS. accompanied Avith severe pain in the back, much increased by any kind of exertion, especially if the lumbar and dorsal muscles are much or actively employed. We frequently find cutaneous eruptions upon different parts of the body associated, or in some way connected, with the deposition of the triple salt. " That tendency to a deposition of these earthy salts in the urine," says Dr. Prout, " is sometimes hereditary, there can be no doubt. Moreover, this tendency often assumes different forms in dif- Figure 18. ferent members of the same family, and even in the same individual at different periods of his life. Thus, Avhen one individual of a family has suffered from a deposition of the phosphates, another has suffered from gout, a second from asthma, a third from cutaneous disease. I have for some time attended a gentleman Avho has been suffering for many years from spasmodic asthma. The urine deposits the phosphates in great abundance. I have also attended the brother of this gentleman, likeAvise his nephew, and three of his children, all suffering from Avhat they name nervousness, which it is said runs in the family. No two, VARIOUS URINARY DEPOSITS. 123 hoAvever, suffer alike. The gentleman told me that he thought he should have lost his life in consequence of having. gone, on the recommendation of a physician, to a watering- place, and drank largely of an alkaline spring. He was reduced to such a degree, and his health so very much shat- tered, that many months elapsed before it was restored to its ordinary state. One can hardly reconcile the probability of such an error, had there been even but an imperfect analysis of the urine. There is scarcely a day passes that I have not applications from members of the profession requesting me to examine the uriue of their patients. This is very often accompanied Avith another, —that I Avould be so good as to forward, by return of post, a report, Avith a full account of the analysis. Perhaps the little attention bestowed upon inquiries of this sort, by gentlemen in general practice, will account for their not being aAvare that days are often necessary before the in- vestigation can be completed, and the analysis perfected. CHAPTER XV. PATHOLOGY OF THE NERVES AND NERVOUS MALADIES. The dominion of the nerves over the mental and physical actions of man is unbounded. The various workings of in- tellect, sensation, volition, motion, secretion, nutrition, — the essence of all these is nervous influence. There is no animal without nerves, but myriads without circulation of the blood. Blood and nerve are, hoAvever, about equally implicated in the phenomena of health and disease. When the nerves are powerfully affected, how quickly the heart is affected also ! Alarm and terror are mental impressions ; but hoAV instantaneously the heart is affected by undue enerva- tion is evidenced by palpitation, increase or arrest of cir- culation, by blush or pallor. The phenomena of mental disorders, or of a class of them, at least, are dependent on an abnormal supply of carbonized or oxygenized blood on the brain, or a deficiency of phosphorus. Excess of arterial or-venous blood will equally induce a train of morbid phe- nomena in the nerve, as in any other organic tissues of the body. There is indeed a marvellous connection betAveen the nervous and vascular systems throughout the animal frame. Too great action in the minute arteries, congestion in the veins, an ansemious or bloodless state of the vascular sys- tem of the brain, alike induce morbidly exalted and impaired conditions of the mental and cerebral functions; spectres, [124] PATHOLOGY OF THE NERVES. 125 delirium, insomnia or sleeplessness, amaurosis, stupor, coma ; violent involuntary actions, or paralysis of the volun- tary motions, etc. The higher the nervous energy, or the more vigorous the circulation of the blood, the greater the poAver of the A'ital tissues to resist contagious diseases. Hope AA'ill preserve the energy of the body under the most depressing influences, the most laborious exertions. The body cannot have rest or health till the mind be satisfied. The nerves are valuable servants, but they are despotic masters. Let them once get the Avhip-hand, and Avoe betide their slave. Noav, have we not an apology to make to them? We either coax and pet and indulge them as Ave do spoiled children, or Avork them to the utmost; and then Ave wonder that their evil qualities turn the tables on ourselves, and render us slaves to the tempter. Let us take a brief glance at those excited conditions of the mind Avhich are so often the spring of ner- vous maladies, real and imaginary. It is true we cannot always " Minister to a mind diseased, Pluck from the memory a rooted sorrow; " but, by a little self-denial, a sound mind (mens sana), to a degree at least, may be preserved to us. If, in the effort, even self-interest or self-gratification be sacrificed, the tran- sient tears of regret will, we may hope, be consecrated, and turned to those of joy and thankfulness, when the struggle is over. Intense impression on the mind is a subject full of inter- est. The illusions so often induced by it are contrasted in their influence o\ov the system. They may be consolatory, an agreeable and happy deception,- and should in some cases be even encouraged. We Avill glance at a story told by Kotzebue, the poet, in illustration. It was of a young lady Avhose lover died. His harp, on which he Ava's wont to 126 PATHOLOGY OF THE NERVES. accompany her, hung in her chamber. After a period of melancholy and grief, she touched the cords of her instru- ment ; the harp, tuned in accordance, responded. Surprise and terror Avere at first the consequences ; but these iioav yielded to a romantic melancholy, Avith a conA'iction that the spirit of her loA'-er swept the strings of the harp. Her music became her only consolation, until a scientific friend explained to her the principle of phonic harmonies. From that moment the illusion vanished, and she drooped and died. But if the impression be foreboding of misfortune, of course it should be removed if possible. We could cite many cases of those unhappy prognostics from dreams, and the prophecy or dread of the fortune-teller, regarding the termination of operations or of childbirth. Anxiety is pros- pective sorroAv, — its subjects A^arious. In that Avhich may be termed moral anxiety, as that of a Avife or a mother for the safety of her husband and her child, there is a sacred- ness Avhich excites our deepest sympathy. Others have a more unholy spring; a heart tainted with pride or avarice, those besetting sins Avhich so deform human nature, and to the pains of Avhich there is no end, —for pride and avarice are never satisfied, — there is no real meaning but a negative one in the Avord enough. These passions are the very bane of existence. Yet Iioav many, even of those wdio decry them, cherish the serpents in their bosom, trusting to honor or riches for sublunary happiness, forgetting the monitory lines of Yroung, — " Why all this toil for triumphs of an hour? What though we wade in wealth or soar in fame ? Earth's highest station ends in ' Here he lies '; And dust to dust concludes her noblest song." The feeling of anxiety is one continued heart-ache; it is the dread "of something worse tbmi the present. It is pro- PATHOLOGY OF THE NERVES. *■** gressive in its degree, and therefore more poignant than real sorrow or grief, Avhich is the pain of memory, and Avhich so constantly, from the mere elasticity of the mind, gradually fftdes and disappears. For the anxious heart there is often no relief, save from the eloquent lips of sympathetic friend- ship, or the consolation of religion. If it be not relieved, Ioav nervous fever Avill be the consequence, with remora of the circulation, inducing local congestions ; then, not only are the secretions diminished, but those which are formed are depraved and unhealthy. For so surely as the enliven- ing passions oxygenize the blood, do the depressing emo- tions accumulate carbon. By this poison a constant morbid and ineffective reaction is going on, Avhich wofully aggravates the original affection. Thus is established a train of ner- vous maladies, — neuralgia, hypochondriasis, melancholy, — inducing that corroding action in the brain, which, in the Avords of the son of Sirarh, "consumeth marroAV and bone." In the end, if the brain be long oppressed by its poison- blood, taidium vitce, or Aveariness of life, must be the result, the climax of which may be suicide. During this progress the system is in a state of universal malady, — all is going wrong. Circulation, digestion, assimilation, nutrition, the nurses of life, fail; absorption of fat succeeds, and atrophy is the result. In the anxious mother, the secretion of the milk is checked or depraved, by Avhich half-poisonous fluid the numerous convulsive and gastric diseases of infancy are brought on. The influence of anxiety also constantly lights up those latent germs of constitutional disease, which might never otherwise have been developed. The miliary tubercle of phthisis is thus excited to action, and youth and beauty, till then in seemingly blooming health, are at once doomed to decay and perish. But the great source of anxiety and its train of ills is to 128 PATHOLOGY OF THE NERVES. be sought in those ardent longings for Avorldly possessions, Avhich are the especial debasement of this age. But even the fullest measure of success in the insane struggle for opu- lence soon palls on the sense. When all earthly grandeur and power are at length attained, the proud and anxious possessor stalks through his gorgeously furnished halls, counts over his millions, and Avonders and deplores (that is, if he can moralize) that his heart "is not sufficiently capacious to enjoy all the splendor, and opportunities of gratification, Avhich it commands. We cannot " Through the loop-hole of retreat Look out upon the world," agitated as it is at this moment with the intense desire of gain, Avith the eager haste to be rich, without a thrill of pity and sympathy for the blind votaries of Mammon, Avho daily and hourly prostrate themselves before the golden image they have themselves set up ! Tranquillity of mind ! It Avere a miracle indeed if such a condition of brain could be preserved amid the tumult of a stock and share market and gold-board, in the face of desperate ventures, in Avhich mil- lions may be involved, and families reduced to irretrievable ruin, in the twinkling of an eye, as it Avere. And it Avere a vain effort to check the headlong course of one on Avhom the monomania of gaming has taken so deep a hold. Yet while Mammon thus reigns in every alley, the health of the body is sapped, the intellect is impaired and perverted, the condi- tion of its organ gradually destroyed, the earthly climax of AA'hich may be drivelling or raving insanity, or death, self- inflicted from the muzzle of the revolver in the grasp of des- peration. On the slaves of pleasure, anxiety is ever an attendant demon. True, the orgies of Bacchus and Yenus, during their intense excitement, droAvn the heart and mind in one voluptuous flood, Avhile the cup of Nepenthe or the lips > PATHOLOGY OF THE NERVES. 129 and arms of beauty throAv their spell over the senses ; but the deep anxiety of after-thought and feeling can never be com- pensated by a thousand-fold of such enjoyment. And is the penalty merely transient? Alas, it lasts a life-time ! It is deeply painful to reflect on the prolific springs of disorder from these slavish passions; the brain and heart are the especial organs into which their poison is infused. Either the intellect or the senses are reduced to a brutal apathy, or the sensitiveness (hyperesthesia) of the nervous system is so morbidly increased, that, on the slightest disappointment, or social competition even, the Avhole system is deranged, and there is no philosophy, no piety, to tranquillize a mind so subdued, for irreligion must be the predominant prin- ciple of such a life. Grief and its prototypes is another fertile source of deep or protracted neiwous maladies. The intense degree of grief is all-absorbing. The mind broods over the one subject of its Avoe, and so reluctant is it to admit another, that it is often annoyed by conversation of friends, or even impression on the senses. Hence, the deep mourner retires into lonely seclusion, and soon may be lighted a train of feelings as dis- tressing as they are obnoxious to remedy — melancholy. When this sad condition is the result of bodily causes, Ave can cure it; but Avhen it springs from moral causes, time, of course, is an element in the cure. But the maladie imagi- naire is mostly the result of mere corporal derangement and break-down. We will conclude our remarks on the pathol- ogy of nervous maladies by glancing at the hygiene best adapted to remedy them. (As for their medical treatment, Ave can best administer that directly and personally, rather than through the medium of a wrork on Nervous Affections. As has already been said, the resources of the Materia Medica for nervous maladies has been powerfully reinforced within the last ten years, by an entirely neA^ class of reme- 130 PATHOLOGY OF THE NERVES. dies, based on our greater knoAvledge of the nervous system and its action. The Avriter himself has introduced a new and most potent remedy.) If Ave believe in the irritation or disturbance of mind as a fertile source of the neuroses, or nervous affections, Ave may also belieA'o that the inducing a different state of mind Avill proATe a curative or preventive oftentimes,—at any rate, a great help to a cure. This state of mind Avould be the oppo- site of pride, envy, hatred, and sordid greed of gain, Avhich passions, as a great moralist remarks, have no holidays, — that Avhich we term repose, — contentment, tranquillity, happiness. By mental repose Ave do not mean the apathetic state of the thoughtless or the slothful; the dolce far niente of the useless do-nothing, is the mere scum on the surface of the cup of idleness Avhich contains a poisonous bitter in its dregs. Under the placid condition of mind, not only is the vis medicatrix alloAved to exert its potent influence, but the various functions of the body are almost ensured, or restored to their former integrity. " To laugh and grow fat" has become a piwerb. Yet, to ensure this happy mood, how manifold arc the precepts, —amusements and moderate occu- pation, and those most congenial to the disposition. But this mental election must not be negative ; the mind must be brought not only to forego those perilous pleasures of sense and of sensibility, to Avhich luxury and sloth are so naturally prone, but also to act on the subject of its thoughts, not with fatigue and labor, but Avith that degree of energy which will afford food for immediate reflection, and the memory of which will be the constant spring of tranquil satisfaction. "We should live pleasant," and regard cheer- fulness as a duty. To ensure this requires often a high degree of self-control, as Avell as the sympathy of friendship. The greatest caution in conversation is sometimes essential ; allusions to subjects Avhich are agreeable, congenial, and PATHOLOGY OF THE NERVES. 131 consolatory to the invalid, should be adopted, both in con- versation and reading ; and objects of beauty and of interest should as much as possible be presented to the mind ; for it has been observed Iioav influential are odor and color and form in mitigation of more decided maladies. Of the antipa- thies of smell and taste Ave have known very curious instances in nervous patients. The olfactory nerves may become so acutely sensitive as to be oppressed by even grateful odors, • so that the poet scarcely exaggerates Avhen he says, — " And quick effluvia darting to the brain, Die of a rose in aromatic pain." The morbid eccentricities of touch or feeling are among the most painful maladies of the neuroses. They are eminently characteristic of hysteria. A lady, Avho Avas for several years under the writer's care for phthisis, Avas occasionally affected with intense hyperesthesia (excessive sensitiveness) of the skin. During this state, a feather dropped on her person Avould instantly produce such intense agony as to • draAV forth a shrill and prolonged scream. But to resume our remarks on the hygiene for shattered nerves. We fear that the lesson which we are endeavoring to inculcate is not so easy in this excited, artificial age. We have, in truth, so multiplied our Avants, that we become restless, if we do not accomplish all the mind can conceive. Like Ariel, Ave wTould put a girdle round the globe in forty minutes or seconds. The age is a nervous one, and hence the desirability — to the Avorld-worn, jaded man — of repose, and the exceeding need of procuring it. CHAPTER XVI. A FEW HYGIENIC OBSERVATIONS ON NERVOUS AFFECTIONS. In regard to nervous patients, Brown-Sequard insists that " A serious aim in the daily occupations is of the greatest value, and for many persons, quite essential to prevent or to check nervous disturbances. The applications of this princi- ple are, of course, he says, very difficult, and often impossi- ble, in certain neuroses; but in those cases in which any kind of serious work, either mental or physical, but not too fatiguing or exciting, is liked by the patient, he should be induced to do it. In cases of hypochondria, of hysteria, of chorea, or even of epilepsy, a great benefit can be derived from a serious employment of the mental and physical activ- ity of the sufferer. How often have I not seen young epilep- tics kept in idleness (alas ! by medical advice), and having gained more or less of the vices it leads to, improve rapidly from having their minds occupied at regular hours, in nearly the same way as healthy people of their age. The second principle of moral treatment is, that we must, in the interest of our nervous patients, as much as, if not more than in our own, give them confidence and hope in the treatment we rec- ommend. In hysterical and all nervous complaints allied with it, and also in hypochondria, a great hope of cure will do much to work out the cure. No doubt you Avill say, But how can vou give hope ? I answer that the best means for " ■ [132] OBSERArATIONS ON NERVOUS AFFECTIONS. l133 that purpose is to have hope ourselves, and to express our hope Avith the accent of conviction. And, as you Avould ask hoAV can Ave command hope in ourselves ? I ansAver that the very knoAvledge of the truth of the principle I am now speaking of, is enough to render one hopeful. I need not now repeat that I am noAV only speaking of those nervous diseases in AArhich the power of the mind upon the body is so great, that under the influence of an emotion, or another moral cause, a sudden or almost sudden cure is not very rare." * It has repeatedly occurred to me to see patients who stated that they had been for years in the habit of taking large quantities of opening medicines to keep up the due action of the bowels, but still without the slightest advantage or even effecting the purpose ; yet have I seen these persons derive infinitely more benefit, in a few weeks, from a few "globules," and strictly attending to the admirable dietetic rules prescribed by Hahnemann, viz. giving up the use of wine, spirits, and all such stimulants, than could possibly have been derived from the adoption of all the routine disci- pline so commonly insisted on. It may be said, and I have no doubt Avith a great deal of truth, that the abstaining from the use of Avine and ardent spirits, with the strict .attention to diet, etc., were really the means of cure; and that the minute doses of medicine in the globules were merely incen- tives to regimen, but in every other particular wholly inert. Upon this, however, as a purely practical man, I need only observe, that it matters but very little to the patient by what means his health has been restored, so that he perfectly regain it; nor can it interest him much what particular plan of treatment has been the truly efficacious one in curing his disorder. But if patients will not be satisfied Avithout tak- ing large quantities of medicine, they may as Avell be grati- * Lectures on the Diagnosis and Treatment of Functional Nervous Affec- tions. By C. E. Brown-Sequard. 134 OBSERVATIONS ON NERVOUS AFFECTIONS. fied and amused Avith globules, or something at least equally harmless, so that they may sustain no injury, Avhile pursuing a rational mode of living, and one conducive to health. Again, I have seen similar benefit, in habitual and obstinate constipation of the bowels, and indeed confirmed ill health, from a feAV months' Avell-regulatcd hydropathic treatment; and such patients have really obtained inconceiArably more advantage from strict observance of these rules, and due attention to diet, air, and exercise, than had accrued from the prolonged adoption of the plans recommended by the most judicious and skilful allopathic practitioners. In such cases, regimen seems to have been an important element of suc- cess. It has been already observed that the dietetic and sanitary measures inculcated by homoeopathy ; the invigorat- ing influence of hydropathy; and the various means at the . disposal of and resorted to by the allopathist, may, Avhen prop- erly applied, prove of the greatest benefit; but on the con- trary, if indiscriminately adopted or injudiciously used, they may prove not only inert, but often Arery injurious. It must therefore be apparent that, as already observed, before Ave can determine Avith any prospect of success on the treatment of disease, Ave must diligently inquire into the nature of the case, so as to ascertain the cause and remove it; for if this be alloAved to continue in operation, it will be vain to expect that the effects will cease,—still less be permanently re- moved. But let us suppose that we should prove successful in checking or suppressing the effects, as may sometimes hap- pen, Avithout subduing the cause, Ave should only aggravate the mischief, and induce confirmed derangement in the sys- tem, the cause of which perhaps no subsequent efforts would be sufficient thoroughly to eradicate. Possibly this may be rendered more intelligible by the folioAving illustration. Purging, for instance, may be occasioned by cold applied OBSERVATIONS ON NERVOUS AFFECTIONS. 135 to the skin while it is hot and perspiring; the perspiration being suddenly and over-precipitately checked, purging is set up on the part of nature to compensate the suppressed action of the skin, and thereby relieve, at least in part, the system by the removal of noxious principles. Any similar derangement of the boAvels may arise from taking too much food into the stomach. Here, then, Ave find the same effect — relaxation of the boAvels — produced by two causes differ- ing altogether in their nature and mode of action. Were we to treat the disorder of the boAvels, so occasioned, by the same means, Ave should most assuredly fail of success, the causes in each being so Arery different; and therefore the treatment should be varied, and suited to the peculiar circumstances of each case. Instead of checking the purging in the first instance, by administering astringents, absorb- ents, etc., the AA'arm bath and the administration of* medi- cines, calculated to restore the suppressed or suspended action of the skin, Avill be more in accordance Avith the true princi- ples of treatment. But, in the second case, in which too much food, or of an indigestible nature, has been the cause of the derangement, the appropriate treatment Avill be its immediate evacuation by an emetic or a suitable laxative. A very frequent cause of nervous affections is, intense or unsea- sonable application of the mind, as in reading Avhile at din- ner. By this untimely exercise of the brain, the blood is diverted from its proper course — viz. the stomach — at a time when it 'is particularly required there to enable the vis- cus to secrete and supply a sufficiency of gastric juice. Such patients cannot be benefited except they alter their habits, because so long as they force the current of blood towards the brain, Avhen the vital fluid is required elseAvhere for the purpose of digestion, this function Avill be impaired, and but very imperfectly performed, and nervous derangement will continue to result. 136 OBSERVATIONS OX NERVOUS AFFECTIONS. Another and very common cause of nervous disorder I have found to prevail much amongst gentlemen engaged the AAdiole day in the city, and Avho seldom take any food till they return home to a six-o'clock dinner. They then indulge too freely in the pleasures of the table, and burden the stomach Avith more food than there is gastric juice to dissohre ; con- sequently a considerable portion of the food remains undi- gested, and, undergoing spontaneous decomposition, gives rise to the evolution of different gases in large quantities in the stomach, painfully distending the organ, and causing belching, acidity, acrid eructations, hiccup, etc. Unless Ave remove the cause by a more suitable mode of living, the effects Avill not cease. Medicines may relieve, but Avill not cure the patient. Nervous disorder proceeding from another and very differ- ent cause, frequently falls under my notice. The affection is attended Avith Auolent nervous headache, severe palpita- tions of the heart, Avith a sense of sinking and exhaustion. It occurs in persons who are engaged for many hours during the day in active exercise of both mind and body, and Avho at certain seasons cannot spare time for refreshment till a very late hour, when the energies of the frame have become, as it Avere, completely exhausted. But even at this late period they are frequently disturbed and called aAvay, before they have had time to finish their repast. Under such cir- cumstances, the frame is enfeebled and overpoAvered before any opportunity for refreshment presents itself, the stomach naturally participates in the general debility, and in conse- quence becomes unequal to healthy digestion. Hence, such individuals emaciate, become feeble, and ultimately are pros- trated both in mind and body. In such cases medicine is of little or no use; nothing but a more rational mode of livino- can restore such persons to health and strength. Indeed it is surprising to see hoAV speedily they recoArer, Avhen, by OBSERVATIONS ON NERVOUS AFFECTIONS. 137 altering their mode of life, the cause of disorder has been removed. Analogies draAvn from the inferior animals often lead us to the knowledge of the true principles of cure. Experience has taught the groom the evil consequences that result from feeding the horse immediately after severe exercise ; and phys- iology unfolds to us the rationale. The blood requisite to enable the stomach to form and secrete a sufficient quantity of gastric juice for the purpose of digestion, has not yet reverted from the muscles, whither the current of blood had been more abundantly directed, to increase the muscular energies and activity, and proportion them to the exertions they were called upon to make while under the stimulus of severe exercise. Hence it is necessary to alloAv the animal sufficient time for repose, that the muscular system may relapse into its ordinary state of quiescence. The animal may then be fed, not only with safety, but with advantage ; the stimulus which the food creates brings an increased afflux of blood to the, stomach; gastric juice is secreted more copiously, and poured in sufficient quantity into the cavity of the viscus, and, acting with energy upon the food, it is readily dissolved, and prepared for its final formation into nourishment. The same laws hold good Avith respect to man; and thus it is that analogies often lead to the adoption of true principles, as well as to their explanation. "Nervousness," says Dr. Trail, "is as much distinguished from all other maladies by mental perversity, as it is by bodily infirmity. Without being criminal or addicted to any particular vices, nervous persons are ill-tempered, peevish, jealous, passionate, and always unreliable. They are un- trustworthy, not because of dishonest motives, but because of uuo-overnable impulses. They are unreliable, not because of intentional Avrong, but because of fickleness of disposition and feebleness of will power. They are very selfish, and 138 OBSERVATIONS ON NERVOUS AFFECTIONS. sometimes mean, not because they lack benevolent emotions and a right conscience, but because their outward conduct expresses their internal conditions. Cure them of their ner- vousness, and they may become agreeable, generous, truth- ful, and faithful, as they have been before. But everything has a cause, and so has nervousness. It has many causes, as many as individuals have unhygienic habits. All personal habits that are unwholesome conduce to it. But in all cases there is some local point of irritation" or obstruction, perhaps trivial in itself, from which the whole trouble proceeds. A person may be very weak, as in cholera or paralysis, with- out being nervous." "He maybe dangerously sick, as of fever, and no one accuse him of nervousness. But if the blood is congested in some part or organ, no matter where nor from what cause, to the extent of disturbing the equilibrium of the circulation, yet not sufficient to occasion acute disease, the person so affected will inevitably have a more or less aggravated form of nervousness. And this fact explains why so many persons are more or less nervous, and why this ailment is peculiar to high civilization." Among the more prominent special causes are too much night work, wTant of sleep, great mental anxiety, indigestible viands, narcotic stimulants, as alcohol and tobacco, late sup- pers, and sedentary habits. Any cause, also, that impairs the vitality and drains the vital fluids, as running sores, fre- quent bleedings, chronic diarrhoea, will result in nervousness. A very torpid liver, a very inactive skin, and prolonged constipation, never fail to occasion severe and obstinate forms of nervousness. Obstruction, therefore, beino- the primary and predisposing cause, and unbalanced circulation the proximate condition, the remedial plan is self-evident. Promote circulation to the Avhole surface as much as possible by occasional bathing, and daily frictions with dry towels ; OBSERVATIONS ON NERVOUS AFFECTIONS. 139 use only plain and simple viands, so that the internal viscera may be unloaded; and exercise as much as possible, within the limits of fatigue. Sleep all you can, avoid all convert sation concerning your manifold miseries, and in due time this nervousness will disappear. Great numbers of men in the vortex of city life seem to suppose that they can indulge constantly and with impunity in sensual excesses, and especially the abuse of Avines and liquors, of good cheer, of venereal pleasures, and intellectual excesses, represented particularly by prolonged watchings and preoccupations with business enterprises, works, etc. But sooner or later all such find their mistake in shattered and disordered nervous systems. The writer has by his remedies enabled hundreds of persons guilty of such habitual excesses and violation of the plainest hygienic laws to escape the consequences of their folly. But he has done it by his insisting, when his reme- dies had done their perfect Avork in restoring the nerves to their wonted healthful action, upon an entire abandonment of previous bad habits and practices, so that the effects of his medicine might be reinforced by a proper regimen and life. CHAPTER XVII. A CURIOUS CASE OF SUPPOSED DEMONIAC POSSESSION. I could very easily fill a dozen chapters with interesting narratives of the manifold illusions, delusions, and hallucina- tions AAdiich I have had to deal with in treating a vast num- ber of nervous cases. These various instances of the maladie imaginaire have been, of course, the results of a disturbed condition of the functions of the brain and nervous system. Several years ago a patient was under my treat- ment, who Avas thoroughly convinced that he was possessed by unclean or evil spirits. This person was a gentleman of uncommon intellectual power and culture, and on all other subjects, except that of his own demoniacal possession, was sensible, rational, and intelligent. On his first visit at my office, he placed in my hands a lengthy account of his sup- posed affliction. It was addressed to me, and Avas in the form of a letter. It is too long for the limits of this volume entire, but I will give the most interesting portions of it, merely prefacing it with the remark that the writer Avas ulti- mately cured of his most uncomfortable monomania, and now looks back upon it with almost the curiosity of a disinter- ested third person. The epistle is subjoined. " Dear Doctor : "It was my intention, some time since, to have Avritten you a short account of the sufferings I have experienced for [140] SUPPOSED DEMONIAC POSSESSION. 141 several years past, from the possession of evil spirits; but in consequence of having been constantly pitied and smiled at, and having met with no one Avho would sympathize with me, Avhenever I have broached such a notion, and instanced myself as a proof of the existence of such spirits, I had almost come to the conclusion not to Avrite at all. Unac- quainted as I am with theological discussion, and Avholly unused to argumentative composition, I am at a loss in Avhat manner to set about an explanation on the subject required." (Here the writer gives a sketch of his life. It seems that he was living Avith his wife and several fine children in the city of New York, engaged in professional pursuits, Avhich yielded him a lucrative income at the time he was attacked by the singular monomania.) "The profits from my profession," he writes, " still continuing on the increase, I at this period entered into some money speculations, which caused me a little anxiety and some pecuniary embarrassment, but I retained all my usual buoyancy of spirit. It was then Avhile taking a quiet walk one evening, far from the busy hum of men, I heard the sound of voices near me, speaking of me. I looked in every direction, but could not discover any one. I got over some banks, thinking that, probably, the persons might have been concealed from vieAv by them; but no human creatures were there. I Avalked away from the spot, still the voices pursued me. I mixed Avith the thickest of the throng in the metropolis; the voices still continued to haunt me, and the words then uttered Avere 'Who is he? — do you knoAV who he is?' The response was, ' He is Satan's oavii.' These words seemed continuously to proceed from the persons I passed. I crossed and re-crossed the streets ; still the same voices followed me. Every one appeared to ask the same or a like question, and there Avas a similar reply. Other queries and ansAvers succeeded to these relat- ing to my walking,—for my pace was very rapid, as I 142 SUPPOSED DEMONIAC POSSESSION. trusted to escape the notice or recognition of the passers-by; but the " Devil's Own " was either whispered or shouted to me, apparently by almost every one; and those from whom the sounds did not emanate, appeared hastily to get out of my way, or, in my imagination, shrunk from me Avith looks expressive of surprise. No doubt, hoAvever, that my strides were those of a possessed person, and caused those I met or overtook to make ample space for me. "The whole night did I thus perambulate NeAv York and its environs, occasionally dozing, as I stood still for a few minutes; and in this manner I tAvice accomplished the cir- cuit of the great city, vainly hoping that daylight Avould end my illusion. Such hope was indeed vain, and I must men- tion, that not merely the " Devil's Own " was sounded in my ears, but observations and conversations relating to me inces- santly occurred. Yet was I perfec^y in my senses. I Avent to the place in which the sounds first reached me, and exam- ined it and the neighborhood minutely; of course I could not discover any human power to account for them. I then began to think of spiritualism, on which I had thought little before, as an explanation of the strange phenomena. . . . The voices loudly and clamorously spoke of all my misdeeds, and taxed me with sins of which I had not been guilty. And I Avas dared to meet the parties Avho charged me Avith such and Avith other crimes. I did accordingly go to a friend of mine, Avho is now dead, and told him I had been affected, and that I wished him to be present to hear the voices, if he could, and the charges to be made against me, Avhich I Avas to deny, or to admit, as the circumstances might be. Sev- eral voices then made various accusations against me, and I appeared to be put on a regular trial. I replied to the, charges by my thoughts, without speaking, but occasionally my tongue could not refrain from moving Avithin my lips, to express my thoughts Avithout, hoAvever, giving utterance to them. SUPPOSED DEMONIAC POSSESSION. 143 " One of the voices Avas remarkably clear and loud. It appeared to be that of a being of authority in conversation with another, and although slightly favorable in his expres- sions of my good conduct throughout life, yet strong and severe Avere his animadversions on my bad thoughts and actions. And here everything I had said or done, or omitted, Avas elucidated instantly ; hidden motives and thoughts and actions Ave re unravelled, to my great astonishment, and my heart and brain seemed completely laid open. All Avas written doAvn or directed so to be, and the next day Avas appointed for a further examination. I asked my friend repeatedly during this trial if he heard any voices. He told me he did not. I mentioned Avhat Avas now and then said to me, and of me. I smiled at myself, for I kneAV I Avas only in a room, and that it Avas impossible for any Avorldly being to speak or communicate Avith me except my friend. I looked at him — he Avas deeply engaged in Avriting; could there be any ventriloquism in the case ? I knew that my friend Avas not thus gifted; besides, the voices Avere Avith me before I saAV him that day. What could have occasioned the sensation of sound I had experienced ; the direct appeal to my heart and brain ? I Avas entirely in my senses, and reasoned on the absurdity of my harboring any opinion contrary to my own received notion of the ordinary laws of nature. I began to think of spiritualism—of clairvoyance. . . . The more I thought, the less could I account for the extraordinary ordeal to which I Avas subjected. I did not believe in evil spirits. ... I did not believe in the commonly received notions of hell-fire, and flames had no terrors for me, nor have they noAV. . . . The next day I Avent prepared for another examination, but I Avas not again put on trial. The parties seemed partly satisfied Avith my mental engagement of com- pensation, as far as I had the ability, of any persons I might have injured in thought, word, or deed. ... I returned; 144 SUPPOSED DEMONIAC POSSESSION. still the voices folioAved me. . . . In the day-time I did not feel the annoyance so much, but in the stillness of night, the torments I endured Avere unutterable — indescribable. The hellish sounds, the dreadful impieties that were spoken of, that Avere foisted on me. . . . When I attempted to pray, I could not, for the jeering and laughter. . . . For change of scene, and hoping I could get rid of the voices, I Avent tAvice abroad. I tried all kinds of amusements, and also the effect of living very Avell, thinking my nerves might be improved by a still more generous regimen than I had ever been accustomed to. These having no effect, I had myself cupped, and entirely altered my diet, living chiefly on vegetables, and avoiding all vinous or spirituous liquors. Nothing, hoAvever, made any difference in my sensations. The sounds accompanied me everywhere, and I still contin- ued the prey of evil spirits. I could plainly distinguish about seven voices : two of them struck me as the voices of females ; one of them sometimes spoke in over-soothing, complaisant accents to me, but these Ave re generally used to turn me into ridicule afteiwards. . . . It is now lhre years and four months that I have had this singular Arisita- tion from God, and although I have no faith in dreams, yet most singularly I dreamt of my father's death about the time it occurred, and I have not dreamt of him since, until the beginning of this month of September, Avhen I dreamt that I saAV him interceding with God for the suspension of my sufferings from evil spirits, and, strange to say, I expe- rienced for a time relief from their presence and perse- cutions. . . . Suffice it to say that the Avriter finally became a firm believer in evil or unclean spirits, and their power to haunt or possess man. He concluded his singular communication to me, Avhich is very long, in the foliowinor words : " It strikes me that many persons, Avho are consid- ered and pronounced deranged, are, really, instead, possessed SUPPOSED DEMONIAC POSSESSION. 145 by evil spirits. It may be said that I may myself be in a state of derangement. To this I Avould oppose these; facts — that I do not pretend to having had any ocular demonstration of any spirit, nor have I had any distorted visions or ideas. I haAre not spoken incoherently, nor have I acted contrary to rationality ; but I have ahvays been blessed Avith my senses, notAvithstanding this heavy calamity of evil possession Avith which it has pleased God to visit me. . . . " I am, sir, your obedient servant, When the Avriter of the above singular account came under my treatment, he had only occasional and greatly mitigated attacks from his imaginary infernal tormentors. In fact, the case had ceased to be very distressing, notwithstanding the patient had become a firm believer in demoniacal influences. He Avas a sceptic, in the height of his monomania and suffer- ing. It perhaps should be remarked that the gentleman Avas the son of Avhat is called an Eurasian; that is, his grand- father Avas English and his grandmother an East Indian lady, Avhich fact accounted for certain psychological peculiarities as Avell as peculiarities of temperament. I easily reinforced the happy effects Avhich the lapse of years had begun to have on this patient's most delicate and excitable nervous system, with a class of remedies specially adapted to such a case, which Avas marked by a morbid condition of the auricular nerve. The patient was completely cured under my treat- ment, and I finally succeeded in demonstrating to him that demoniacal possession was nothing more nor less than one of the forms of nervous malady. The belief in possession by unclean spirits Avas natural enough in ages of ignorance and superstition, when the mysteries and peculiarities of the nervous system Avere not in the least understood, and per- sonal agencies Avere supposed to account for everything. CHAPTER XVIII. HOPE AND CONFIDENCE AS THERAPEUTICAL AGENTS. The physician who cannot inspire hope and confidence in his patient, might as well understand that he has mistaken his calling; and just in proportion as the medical man is able to excite these two exhilarating, buoyant, and curative emotions in the breasts of those Avhom he treats, just in that propor- tion ordinarily Avill be his success. In treating diseases of the melancholic-nerArous class, especially, the physician Avithout self-reliance cannot hope to beget reliance in his patient. A third thing, says old Burton, in his famous book on Melan- choly, to be required in a patient, is confidence, to be of good cheer, and have sure hope that his physician can help him. Galen, the old Greek physician, holds confidence and hope to be more good than physic. He cures most, in Avhom most are confident. The great success of another old Greek physician, Hippocrates, was accounted for on the ground that the common people had a most strong conceit of his worth. The young student of medicine is told in Faust, " If you on yourself rely, Others on you will place reliance." It is Avonderful the healing effect which a hopeful, confi- dent state of mind in the patient has upon his disease. But when one considers the intimate connection of mind and [146] HOPE AND CONFIDENCE AS THERAPEUTICAL AGENTS. 147 body, the mystery is solved. Reputation and wide-spread notoriety are valuable to a physician, because they give him a power and sort of magical influence over the mind of his patient. This influence, too, may be given by personal qual- ities, such as appearance, etc. There is a certain genius for the cure of disease, and an intuitive insight into the ills to which flesh is heir, which some men possess, and wdiich are more valuable than the fruits of the profoundest study. A perusal of the lives of eminent physicians Avill convince one of the fact, or an acquaintance with one of these natural con- querors of disease. Their presence inspires a certain con- fidence in the patient, a sort of magnetic influence, which reinforces the medicines administered, and causes the happi- est effects. Professional jealousy and rivalry may cause these born physicians to be denounced as quacks and empirics, but the public cannot be diverted from recourse to such. Per- sonal power, a strong will, is as necessary in a conqueror of disease, as of armies. In nervous-melancholic maladies, the first thing Avhich the physician has to contend against in his patient, is a fearful depression and downheartedness. Out of this abyss of despair he must be able by his will to lift the victim of nervous malady who has recourse to him. For the victims of nervous disease dwell, as it Avere, "in a land of darkness, as darkness itself; and of the shadow of death . . . and Avhere the light is as darkness." To quote from quaint old Burton again : " Of those diverse gifts which our Apostle Paul saith God hath bestoAved on man, this of physic is not the least, but most necessary, and especially conducing to the good of mankind. Next, there- fore, to God, in all our extremities ('for of the most high cometh healing'), we must seek to and rely upon the physi- cian, who is ManusDei (the hand of God), and to whom he hath given knowledge, that he might be glorified in his wondrous works. With such doth he heal men, and take 148 HOPE AND CONFIDENCE AS THERAPEUTICAL AGENTS. away their pains. When thou hast need of him, let him not go from thee. When Ave have now got a skilful, an honest physician to our mind, if his patient will not be con- formable, and content to be ruled by him, all his endeavors wall come to no good end. Many things are necessarily to be observed and continued on the patient's behalf: first, that he be not too niggardly miserable of his purse, or think it too much he bestows upon himself, and, to save charges, endanger his health. The Abderites, Avhen they sent for Hippocrates, promised him what reward he Avould, "all the gold they had, if all the city were gold he should have it." Naaman the Syrian, Avhen he Avent into Israel to Eiisha to be cured of his leprosy, took with him ten talents of silver, six thousand pieces of gold, and ten changes of raiment." We are not sure but that Burton's Anatomy of Melancholy is not even yet the best treatise on Nervousness and Nervous Maladies, quaint as it is. "Melancholy," he says, "is either in disposition or habit. In disposition is that transitory mel- ancholy, which goes and comes upon every small occasion of sorrow, need, sickness, trouble, fear, grief, passion, or perturbation of the mind; any manner of care, discontent, or thought Avhich causeth anguish, dulness, heaviness, and vexation of spirit; any ways opposite to pleasure, mirth, joy, delight, causing frowardness in us, or a dislike. In which equivocal and improper sense, Ave call him melan- choly, that is, dull, sad, sour, lumpish, ill-disposed, solitary, any way moved, or displeased. And from these melan- choly dispositions, no man living is free; no stoic, none so wise, none so happy, none so patient, so generous, so godly, so divine, that can vindicate himself. Melancholy in this sense is the character of mortality. The name is imposed from the matter, and the disease denominated from the ma- terial cause, Ariz. black bile." Among the causes of melan- choly he includes the imagination, which, he says, as it is HOPE AND CONFIDENCE AS THERAPEUTICAL AGENTS. 149 eminent in all, so most especially it rageth in melancholy persons. . . . This Ave see verified in sleepers, AArho by reason of humors and concourse of vapors troubling the phantasy, Avill give many times absurd and prodigious things, and in such as are troubled with incubus (night- mare), if they lie on their backs, they suppose a hag rides and sits hard upon them, that they are almost stifled for Avant of breath. . . . This is also, evident in such as walk at night in their sleep and do strange feats. . . . All ecstacies are referable to this force of imagination, such as lie Avhole days together in a trance ; as that priest Avhom Celsus speaks of, that could separate himself from his senses when he list, and lie like a dead man void of life and sense. . . . Many times such men, Avhen they come to themselves, tell strange things of heaven and hell, what visions they have seen. . . . The like effects, almost, are seen in such as are aAvake; hoAV many chimeras, antics, golden moun- tains, and castles in the air, do they build unto them- selves ? " CHAPTER XIX. ALCOnOL, TOBACCO, OPIUM, HACSHISH, LEAD. It is through the nerves that the five dread agents enu- merated at the head of this chapter have their fearful hold upon humanity. These five agents are continually making war upon the healthy equilibrium of the nervous system, and through that deteriorating the race. The symptoms of alcoholic poisoning are those of alternate excitement and depression. Partial paralyses are but the precursors of more grave affections, which terminate finally in general paralysis, deterioration, and ultimate loss of intelligence. A. French Avriter maintains that insanity is merely the last degree of degeneracy. In the first generation you have immorality, depravity, alcoholic excess, brutish disposition ; in the second, hereditary drunkenness, maniacal accessions, and general paralysis ; in the third, sobriety, hypochondriac and maniacal tendencies, systematic ideas of persecutions and homicidal impulses; in the fourth, Aveak intelligence originally, access of mania, stupor, transition to idiocy; finally, extinction of the race. M. Morel, the French writer, already alluded to, asks, in his work on the " De- generacy of the Human Race," what may be the part which tobacco plays in the production of degeneration? And admitting even that its degenerative action is an ascer- tained fact, how far Avould it be good medical hygiene to [150] ALCOHOL, TOBACCO, OPIUM, HACSHISH, LEAD. 151 attack the usage of tobacco, which has become for all nations not only a habit but an imperious necessity, to be satisfied at any risk? I have no intention, he says, of attacking its use, and this for many motives : first, it is far from being proved that the habit of smoking, in moderation, is in atiy Avay injurious; and, secondly, it would not be without dan- ger to iiwoke the force of an absolute legislation against a habit passed into such an irresistible necessity. Medical men engaged in the investigation and treatment of the dis- eases of the brain and disorders of the mind, occasionally have brought under their notice cases of severe nervous dis- order and mental impairment, clearly traceable to an exces- sive and immoderate use of tobacco. Shattered nervous system, premature loss of mental vigor, impaired memory, mental alienation, arc too often the Avell-defined result of excessive tobacco-smoking. These are facts that cannot be ignored when considering the question. If society Avere in a more natural condition, or one more in accordance Avith the most obvious rules of hygiene, it is highly probable that no poisonous agent, whether narcotic or stimulant, would be habitually desirable or alloAvable. It would not be easy to define accurately what is a natural state of society ; but it is easy to say what is not. For instance, it is not natural for man to pass his life underground, as in mines ; to be exposed, in addition to the ordinary atmospheric changes, to those of moisture and cold, in connection with sieges and the life of armies in active service, and to migra- tions from mild to extreme climates and new conditions of existence ; to be immersed perpetually in poisonous or irri- tating vapors, as in various branches of art or industry; to be suffering the extremes of misery, privation, and heredi- tary disease. It does not appear improbable that in the war- fare Avith evil influences Avhich man is constantly called upon to AA^age, that within moderation the use of tobacco may have 152 ALCOHOL, TOBACCO, OPIUM, HACSHISII, LEAD. as beneficial effect in enabling him to resist successfully some of these influences, as any other prophylactic agency may have in other cases. It may be injurious to the normal con- stitution normally treated, but may it not avert or resist the abnormal consequences of a different condition ? In other words, the use of tobacco in moderation, and under circum- stances of great hardship and privation, is upheld by many men of high scientific attainments and sound judgment, as not only not injurious, but beneficial. Then, again, it is said by high authorities, that cases of general paralysis and soft- ening of the brain are fearfully multiplied by tobacco-smok- ing. As for opium, that is an agent whose effect upon the nervous system is of an appalling character. The use of this seductive drug is enormous. The Indian hemp or Hacshish forms the basis of most of the intoxicating prepa- rations in Egypt, Syria, and most Oriental countries. The leaArcs arc smoked alone or mixed Avith tobacco. Besides the habitual hallucinations Avhich the extract of Indian hemp produces in some individuals, its prolonged usage induces incurable dementia. There is reason to belkwe that such is the case in many persons met Avith in the cities of Egypt, who are venerated as holy men (santons) by the people, but who are merely fallen into a state of dementia from the use of hacshish. To return to tobacco for a moment. A dis- tinguished English physician avers his belief that cases of general paralysis are more frequent in England than they used to be, and he suspects that smoking tobacco is one of the causes of that increase. He further believes that if the habit of smoking advances in England as it has done for the last ten years, that the English character will lose that com- bination of energy and solidity that has hitherto distin- guished it, and that England will sink in the scale of nations. Tobacco is reprobated because it produces insanity, paralysis, consumption, laryngitis, tonsillitis, short sight, emaciation, ALCOHOL, TOBACCO, OPIUM, HACSHISH, LEAD. 153 dyspepsia, and an infinity of minor disorders. It is upheld because it is pleasant; because it is a valuable therapeutic and hygienic agent, a preservative against cold and starva- tion, a substitute for food, a solace to the Aveary, Avhether of mind or body. One Avriter attempts to settle its value by an appeal to final causes, asking, "Why was tobacco created, if not to be smoked ? " perhaps overlooking the fact that the Same trenchant argument applies to every vice. Another writer says, if the evil ended with the individual Avho, by the indulgence of a pernicious custom, injures his own health and impairs his faculties of mind and body, he might be left to his enjoyment, his fool's paradise unmolested. This, how- ever, is not the case. In no instance is the sin of the father more strikingly visited upon the children than in the sin of tobacco-smoking. The enervation, the hypochondriasis, the hysteria, the insanity, the dwarfish deformities, the con- sumption, the suffering lives and early deaths of the children of inveterate smokers, bear ample testimony to the feebleness and unsoundness of the constitution transmitted by this per- nicious habit. This is the age of narcotics and narcotism, and they undoubtedly have much to do Avith the marked in- crease in the number of cases of disease of the brain and nervous system. We think the fact is indisputable. Phy- sicians Avho have favorable opportunities of investigating this subject, not only agree in opinion that such diseases are of more frequent occurrence, but that a certain unfavorable (but in its incipient stage certainly not incurable) type of cerebral disorganization develops itself in the present age at a much earlier period than formerly. Softening of the brain, for example, now manifests itself at the early age of thirty and thirty-five! It is indeed lamentable that the brain and mind should yield to the influence of certain nox- ious moral and physical agents, at a time of life when the intellect ought to be in an active and vigorous condition of exercise and health. 154 ALCOHOL, TOBACCO, OPIUM, HACSHISH, LEAD. Speaking of the immense use of narcotics, let us take China, Avhose habit of opium-smoking has invaded Europe and our Pacific slope. Neither tobacco nor Indian hemp (norperhaps alcohol) compares Avith opiums either in the con- stitutional result, or in the difficulty of breaking the habit. China presents a curious spectacle of moral disease. Three hundred millions of individuals united under one absolute government, speaking the same language and having • identi- cal religious notions, present to us the sad spectacle of a people menaced, as to its dearest interests, by the most fatal and degrading habit that it is possible to conceive — that of smoking opium. The effects of this habit, immediate and remote, are thus described: "The first impression is a feel- ing of content and slight excitement, manifested by loquacity and involuntary laughter. Sometimes there are fits of anger. Soon the eyes become brilliant, and the respiration and circulation are quickened and excited. At this stage of the nervous exaltation, the smoker feels a peculiar comfort, and the temperature is augmented. The impressions are lively, and the imagination wanders into strange illusions. Now we observe a phenomenon frequently remarked in men- tal alienation. Facts and ideas, long forgotten, present themselves to the mind in all their original freshness. The future appears all bright, and every happiness ever AArished for appears realized by the smoker. If he continues smok- ing, exaltation gives place to depression and utter prostra- tion. The action of the senses is suspended. He hears nothing ; he becomes silent; his face becomes pale, his tongue hangs out; a cold sweat inundates the Avhole body ; and insensibility supervenes, often lasting for several hours. The awakening is what might be expected after such a debauch." Except some feAv smokers, who, thanks to an exceptional organization, can restrain themselves Avithin the bounds of moderation, all the others attain rapidly a fatal termination, ALCOHOL, TOBACCO, OPIUM, HACSHISH, LEAD. 155 having passed in quick succession the stages of idleness, debauch, misery, the ruin of their physical strength, and the utter degradation of their moral and intellectual faculties. Nothing can cure an advanced smoker of opium. Another poisonous agent Avhich Avages Avar upon human- ity and conduces to degeneracy, is lead. There are analo- gies betAveen lead colic, and partial lead paralysis, and alcoholic poisoning. There is, in the commencement, trem- bling, Aveakness, and paralysis of the loAver extremities, and diminution of the general sensibility. Soon there are twitchings and cramps, dizziness, fantastic dreams and hal- lucinations ; and these are exactly the symptoms of the anaesthetic form of alcoholic poisoning. These are the symptoms inseparable from all chronic poisonings; and more than that, they are the essential signs which announce, by their duration and their constant progress, that the indi- vidual is smitten in the most important functions, and is tending to degenerate transformation more and more radi- cal. Those A\rho present the first signs of the action of the poison of lead, as the blue line in the gums, and the yellow tinge of skin, appear for a time to be quite Avell; all the func- tions are correctly performed ; the subject complains of no pain, and folio avs his employment as usual. The nervous lesions which ultimately occur assume all forms of delirium, coma, epilepsy, etc., sometimes after several attacks of colic, sometimes unpreceded by it. After the occurrence of these, especially the epileptic seizure, the reason is never sound again. In lead poisoning, the individuals affected are too feAv, comparatively, and the fatal termination too sudden, to permit any Arery definite calculation as to the effect finally upon the race. But the effects which the use of alcohol, tobacco, and opium, Avide-spread as it is and has been, has had upon the Nervous System of the Race, both directly and by transmission, must defy calculation. What a sum- 156 ALCOHOL, TOBACCO, OPIUM, HACSHISH, LEAD. total of degeneracy and degradation, both moral and physi- cal, have these mighty agents of nervous elevation and depression caused! What wonder that general paralysis and softening of the brain are becoming the most frequent diseases mentioned in the death-list! No one is ignorant that many organic dispositions in the human race are trans- missible from one generation to another; but it is not gen- erally known hoAV far this principle extends. It is believed in general that form and appearance are transmissible, but it goes much further than this. It is ascertained that all mor- bid dispositions, all pathological predispositions, are inherit- able from parents to children, as avc.11 those belonging to the organs of vegetative as of animal life. The predisposi- tion to nervous maladies, to epilepsy, to mania, is transmissi- ble as well as that of gout, rheumatism, scrofula, etc. Now the predispositions have not constantly existed in all preced- ing generations, but have been acquired by some part of the ancestry, and handed down to the descendants, the morbid taint becoming moro and more pronounced in every genera- tion. Whatever may be the form of the physical degradation, and Avhatever the nature of the lesions experienced by the individual, Avhether arising from alcohol, opium, or other causes, it is not necessarily the same typical form, nor the same lesions, Avhich are to be expected in his descendants. The deviation from the normal type of humanity sIioavs itself in succeeding generations, by internal and external signs perhaps much more alarming: since they represent enfee- bled faculties, an addiction to the Avorst tendencies, and the limitation of intellectual life to a certain period, beyond Avhich the individual is no longer in condition to fulfil the functions of humanity. In contemplating successive generations under these unhappy conditions, Ave observe a series of manifold nervous phenomena having in general a convulsive type ; and forming those pallid, suffering, and morbid temperaments, ALCOHOL, TOBACCO, OPIUM, HACSHISH, LEAD. 157 as well as those incredible moral perversities and intel- lectual aberrations, which, by their nature and frequency, justly astonish those Avho have not watched intently the for- mation of such degenerate races. As long ago as the last part of the eighteenth century, the abuse of alcoholic liquors in SAveden had produced a degeneracy in stature and physi- cal strength among the people of that country. In this country, at the present time, the annual list of the victims of alcoholism is enormous. The moral effect of the use of opium in China is marked. It is almost impossible to imag- ine, says Hue, the readiness Avith Avhich the Chinese commit suicide. The merest trifle, or a Avord, induces them to hang or droAvn themselves, the favorite modes of suicide. Mental aberration, serious as it is in any point of view, in this light becomes doubly so, when it is not merely an individual affec- tion, but the fatal climax, and as it were resume of a long line of individual and hereditary affections. It is easy to con- ceive how, from one generation to another, the moral and physical condition is greatly deteriorated, when what was the habit merely of one generation, became an instinct and impulse in the next; when, added to the hereditary taint, was the force of example positively, and negatively the absence of all instruction and useful education; when to the disease of the mind already existing, either actually or potentially, was systematically denied the exercise of the commonest rules of hygiene or therapeutics, and the ordinary restraints of morals and religion. In cases representing so deplorable an ancestry as this, medicine will do little in altering the condi- tion of the individual, Avhich may be considered virtually beyond cure ; but there remains a noble part to play in the enunciation of principles Avhich, when carried out, wall tend to the removal of those causes to which so many of these evils are attributable. CHAPTER XX. BODY VS. MIND. It is a curious and interesting study to trace the variety of opinions Avhich have been held concerning the respective existence and the mutual relations of the Body and the Mind, — opinions which have, in turn, taken up every position between the absolute non-existence of Mind, save as a form or function of Matter, on the one hand; and, on the other, the merely phenomenal existence of Matter dependent upon the variations of a sentient or thinking immaterial existence, — the Mind. The scientists now generally maintain that Mind is a result of organization. But for ages the belief has been that man is a compound being, consisting of a material man, the Body, and an immaterial active principle, the intelligent Mind. Those that maintain this doctrine are now called animists, from anima, the soul. In the old gentile nations the body was carefully trained along with the mind. But under the peculiar vieAvs of Christianity, Avhen it Avas introduced into the world, the body became gradually neglected and despised, though this result was naturally of tardy growth. Chris- tianity was not at the start muscular, as the phrase noAv is. The Christian doctrine of immortality, though a belief in immortality Avas not peculiar to Christianity, gaAre to the mind, or spirit, which was supposed to be the deathless prin- [158] BODY VS. MIND. 159 ciple in man, a supremacy over the body in the estimation of believers Body and Mind began henceforth to be held, by philosopher and Christian, to have separate and antagonistic interests. To the former, the body was a clog, an impedi- ment to the acquisition of knoAAdedge, a something perpetu- ally interfering, by its pains, its sorrows, and its imperfections, with the clear vieAvs of truth Avhich he supposed the unencum- bered soul Avould obtain,—constantly distracting the atten- tion by its material relations and requirements, — ever of the earth, earthly,—tending to its own source, bending and drag- ging the soul along Avith it. To the Christian, the body Avas sin incarnate, the source of all evil and temptation, the bar- rier betAveen the soul and heaven. In the early centuries of our era, the body seemed to be of ever less and less estima- tion. There is something even amusing in the excess of contempt in Avhich it Avas held and the abuse heaped upon it. A prison-house, a cage, aweary load of mortality, — these were by comparison complimentary terms. One old ascetic Christian writer, a saint of course, calls the body " an ill-sav- ored sink," " a begrimed, pestiferous Avorkshop," " a lump of flesh, Avhioh mouldereth away and draweth near to corruption while Ave speak of it. " The torments of the body Avere so utterly despised as to be scarcely considered personal matters. In fine, the body Avas considered the source of all evil, and, as such, Avorthy of no consideration. The saints and philosophers held that these our mortal members do pro- duce the effect of fear, desire, joy, and sorroAv, in our bodies ; from Avhich four passions the whole inundation of man's enormities have their source and spring. One old sect of religionists held that the body Avas so evil, that its crea- tion cannot be ascribed to the same author as that of the soul. They held all flesh the Avork of the Devil. In their opinion the oreat object of the government of the God of light was to deliver the captive souls of men from their corporeal 160 BODY VS. MIND. prisons. Of course these folks must have regarded a skilful physician as a servant of the Evil One, because he cured the body of disease, and prolonged its existence. Thus did theology cause an antagonism, a division of in- terests, so to speak, between the material and the immaterial elements of man's nature,—one Avhich in various forms, in accordance Avith the spirit of the times, has been propagated even until the present; iioav one and noAV the other being held in paramount esteem, in accordance with the demands necessary to be made upon their functions. Here, brain has been had in honor; there, thews and sineAvs. But the pres- ent is essentially an iron and a practical age ; both strong limbs and thoughtful minds are in requisition; and the spirit of the age is in nothing more manifest than in the manifold attempts, by the spread of national education and the increased attention to the sanitary condition of the masses, to balance the interests of these hitherto conflicting elements. The present prime minister of Great Britain, Mr. Gladstone, about half a generation ago, said, "There still remains in some quarters a vulgar notion that there is a nat- ural antagonism betAveen corporeal and mental excellence. I trust that corporal education will never be forgotten ; that the pursuit of manly sports Avill ahvays receive the counte- nance and encouragement, not only of the boys Avho engage in them, but of the masters who are responsible for the welfare of those boys." These Avere memorable words at the time they were uttered, and produced an effect which is perceptible on both sides of the water, especially in our colleges and schools. Noav, our leading clergymen are foremost as hunters and fishers and rovers of the forest and lake. Fifteen years ao-o, before the revolution in regard to gymnastics in our institu- tions of learning had fully taken place, the " London Times " said, " It Avas a great point in ancient philosophy, the value it BODY VS. MIND. iDl attached to the body, and the proper training of it, the pres- ervation of its health, strength, and all its proper poAvers. Ancient philosophy did not despise the body, did not regard it as a mere husk and outside of human nature, or treat it as a despicable and absolutely vile thing; it regarded the body as a true part of human nature, deserving of proper deference, for the failure of Avhich it Avas sure to retaliate upon the Avhole man. Hence the gymnastics of the Greeks, which were not only fostered by the boxers and Avrestlers, but went on under the solemn sanction of sages. There is a distinction betAveen ancient and modern thought on this subject, and the ancient has certainly the advantage over the modern in this particu- lar point — at least over the modern before the latest im- provements. It has been too much the fashion Avith us to decry the body, to talk it doAvn, to speak scornfully of it in every possible Avay, to be always comparing it Avith the mind for the sole purpose of showing how vile and Avorthless it is in comparison, — a mode of speaking Avhich if it be abstractly true, may be indulged in such a degree as to involve a prac- tical untruth. . . . After all our sublime abuse of the body, a body man has, and that body is part of himself; and if he is not fair to it, he himself Avill be the sufferer. The Avhole man will be the sufferer, — not the corporeal man only, but the intellectual man as Avell. If the body is thoroughly out of condition, the mind will suffer. It may sIioav a morbid enlargement of one faculty or another, but the direct- ing principle — that Avhich alone can apply any faculty or knowledge to a good purpose, can regulate its use and check its extravagances — is Aveakened and reduced. Hoav miser- able is the spectacle of morbid learning, with its buried hoards, and its voracious, insatiable appetite for acquisition, united Avith the judgment of a child ! Such study does, hi short, leave men children with remarkable memories and 162 BODY VS. MIND. acquisitive poAvers, who knoAV as much history, philosophy, and poetry as Avould make a learned man, but Avho are not a bit nearer being men in consequence, because they simply knoAV by rote Avhat they know, — they do not understand their oavii knoAvledge. This is to a considerable extent the case with all morbid learning, where the general intelligence has not been cultivated, — Avhich general intelligence depends on the soundness and health of the whole man, body and mind too. The picture of a Kirke White dying at the age of tAventy-one of nocturnal study, Avet towels round heated temples, Avant of sleep, Avant of exorcise, want of air, want of everything Avhich Nature intended for the body, is not only melancholy because it is connected Avith an early death : it is melancholy, also, on account of the certain effect which Avould have followed such a course unchecked if he had lived. We see, Avhen Ave look down the A'ista of such a life, an en- feebled and a prostrated man, very fit to be made a lion of, like a clever child, and to be patted on the head by patrons and patronesses of genius, but Avithout the proper intellect and judgment of a man. Hoav sad even is the spectacle of that giant of German learning, Neander, lying his Avhole length on the floor among his books, absorbing recondite matter till the stupor of repletion comes over him, forgetful of time and place, not knoAving Avhere he is, on earth or in the moon, led like a child by his sister to the lecture-room when the lecture hour came, and led away home again, Avhen it is over. Is this humanity, we ask, as Providence designed us to be ? Is it legitimate, rational human nature? It can hardly be called so. We must not let the mind feed itself by the ruin of the body. The mind has no right to this indulgence, this dissi- pation and whole-length abandonment to its cravings, any more than the body has to sensual indulgence. This mental drain, the noxious stimulant Avhich produces this overgroAvth of mind, is as contrary to nature as the coarser stimulant BODY VS. MIND. 163 which unduly excites the body. The mind should be a good, strong, healthy feeder, but not a glutton. We have no right to despise the body, or to speak of it only and exclusively as something which is Aule in comparison Avith the mind. This language Avill lead astray; it will make ardent, ambitious student youth neglect health, and abandon themselves to the process of acquisition at the cost of body, and ultimately of mind too. Do not use too unsparingly the motive of ambi- tion in dealing with youth. It is a motive Avhich is perfectly honest and natural Avithin proper limits, but when pushed to excess it produces a feeble, sickly, unmanly groAvth of char- acter; it creates that whole brood of fantastic theorists, sentimentalists, and speculators, which in art, science, and theology alike, are the seducers and the corrupters of man- kind. Nowadays there is happily no danger of neglect of the body. The mind is iioav studied in connection Avith the nervous system. Brain and mind are now used convertibly. The brain proper is the one organ which increases from the fish to man in proportion to the intelligence. It is iioav rec- ognized that without a healthy body the mind cannot be healthy or sane. Within'a feAv years past we have seen the students of our oldest university contending with those of an English university, not in scholarship', but in the purely physical art of rowing. It is scarcely necessary to allude even slightly to the proof that the brain is the material organ (and the only one) through which the mind acts, and communicates with the external world,—this is generally aeknoAvledged. It is less understood that the brain, as an organ, is subject to precisely the same laAvs, chemical, dynamic, and automatic, as other organs and tissues. It is also not disputed that every action of the body is attended by the phenomenon of nutri- tion, including the decomposition of some of the' old tissue, and the supply of its place by new particles; and that the 164 BODY VS. MIND. evidences of such decompositions in the blood and the excre- tions are in exact ratio to the energy and and continuity of such actions. But although the laws of nutrition are in as active operation in the brain as in any part of the system, Ave find it at first difficult to realize the fact so well established by undisputed physiological testimony, that these acts of nutrition are in their essence the necessary conditions of every act of intelligence, perception, or volition ; that, like all other tissues actively concerned in the vital operations, nervous matter is subject to a waste or disintegration, Avhich bears an exact pro- portion to the activity of its operations ; or, in other Avords, that every act of the nervous system involves the death and decay of a certain amount of nervous matter, the replacement of Avhich Avill be requisite in order to maintain the system in a fit state for action ;* in short, that every idea, every emotion, every act of volition, and every perception, however passive or fleeting, is necessarily attended by a waste and decay of a certain portion of brain tissue. Carpenter says, " In the healthy state of the body, when the exertion of the nervous system by day does not exceed that which the repose of the night may compensate, it is maintained in a condition which fits it for moderate constant exercise ; but unusual demands upon its powers — whether by the long-continued and severe ex- ercise of the intellect, by excitement of the emotions, or by the combination of both in that state of anxiety which the circumstances of man's condition too frequently induce — produce an unusual waste, which requires for the res- toration of its powers prolonged repose." It is certainly inexplicable how matter and mind can act and react one upon another; the mystery is acknowledged by all to be past finding out, and will probably ever remain so ; the co-ordinate phenomena, however, are open to investio-ation, and it is clearly ascertained that to certain mental condi- * Carpenter. BODY VS. MIND. 165 tions a certain state of the material organ is attached; and for certain mental acts, certain chemical changes in this organ are requisite. A German physiologist says, " With- out phosphorus, Avithout thought. A due supply of arterial blood is requisite for the proper action of the mind. Loss of consciousness folio avs abstraction of this stimulus. The quality of the blood circulating through the brain also influ- ences the development of ideas ; if it be deficient in oxy- gen, delirium of course follows. The digestion of food introduces a quantity of imperfectly assimilated material into the circulation; until this new material has undergone the necessary changes, and while certain matters, altogether unfit for nutrition, are mingled with it, it is not adapted to excite those states of the brain which are necessary for the proper manifestation of mind; and as it is conveyed to that organ by the circulation, it produces an injurious change in it, and impedes or destroys the mental functions. Hence the indisposition to mental labor experienced by some persons after meals."* The same effects are produced in a more marked degree by Avine, spirituous liquids, narcotics, and the presence of bile or urea in the blood. The organic affec- tions of the brain necessarily and obviously modify the men- tal conditions, not only by destroying the efficiency of a certain portion of the tissue, but by interfering Avith the due per- formance of the organic changes in the other parts. 'All this is sufficiently comprehensible, that the organ being deranged is no longer capable of performing the behests of the mind. It is much less so how the derangement of the immaterial essence can effect the organic structure; yet the fact is indis- putable-. The simplest illustration may be dnvwn from an occurrence not unfrequent in ordinary experience. A per- son in perfect health receives a letter containing, perhaps, some fatal neAVs; he drops down, smitten with appolexy, and after * Miiller, 166 BODY VS. MIND. death it is found that the cerebral tissue is torn by an effu- sion of blood into its substance. Joyous emotion may jaro- duce the same or analogous result. A young Frenchman recehred a complimentary letter from the Directory; he wTas struck motionless, and his head immediately became affected in a manner from AAdiich he never recovered. The paleness of the skin, and Aveakness of the circulation accompanying the depressing emotions ; blushing, and other determination of blood ; excitement of the arterial action, under the influence of anger and the allied passions, — all illustrate powerfully and sufficiently the force of mind. Enough has been said to show the powerful influence which states of mind have upon the body. CHAPTER XXI. GENERAL PARALYSIS. A preliminary idea of the nature of the affection of which we speak may be obtained by a glance over the various names by Avhich it has been known. It has been called general paralysis of the insane, paralytic insanity. Incomplete and progressive paralysis, from its symptoms and its connection Avith mental disorder, from its usual pathological characteris- tics it has been termed sIoav or chronic meningitis, and men- ingo-cerebritis. It is a disease which may be briefly said to be characterized by disorder of the intellectual and volitional poAvers, —not ahvays, or even generally, in strict proportion one to the other. The mental affection is usually of the expansive character, attended by exaggerated notions of the Avealth, position, or personal qualifications of the subject, terminating in dementia, or total eclipse of the mind. The physical disorder consists in a progressive Aveakness and un- certainty of action of the voluntary muscular system gener- ally ; in a majority of cases, beginning Avith the muscles of the tongue, and those connected with articulation, so that stammering is very often the first symptom of the invasion of this affection. In a patient who has evinced any tendency to mental derangement, there can be few symptoms of more serious import than this, —a tendency to stammer, or a diffi- culty of pronunciation of certain words; it may be appre- [167] 168 GENERAL PARALYSIS. hended with a great amount of certainty that general paral- ysis is imminent, and that death, soon or late, wall folloAV as the almost necessary result, let the physical health have been up to that time ever so good. It may be expected that very soon the tongue and the muscles of the face Avill act irregu- larly and tremulously, and that this feebleness and uncer- tainty of function Avill extend to the entire locomotive system, sometimes attacking first the inferior and sometimes the supe- rior extremities. The term " general paralysis " is, hoAvever, someAvhat deceptive, as not indicative of the absolute phe- nomena of the disease in its progress. It is not until the latest stages that the paralysis becomes truly general, and no voluntary power is left, not even of the sphincters. But it is in so fir general that it is not hemiplegian or paraplegia, nor local paralysis, differing from all these essentially, inas- much as all the muscles of the body are indiscriminately liable to be attacked, and sooner or later are so affected. It is rather singular that a disease so well marked in its phenomena, and so serious in its results, should only have attracted attention in so comparatively late a period of medical history. Many of our hospitals for the insane simply refuse admission to patients affected with paralysis, as being incurable. This is a highly important subject, and why ? it is getting to be, even numerically, very prominent in the causes of death affecting our bills of mortality, much more so than has hitherto been suspected. There are forcible reasons, in a scientific point of vieAv, Avhy it is deserving of special attention. The physical causes of insanity are hitherto involved in great uncertainty. Some pathologists go so far as to assert that in a majority of changes cases of simple derangement of intellect, no morbid condition of the nervous centres can be detected, and that in a majority of the remainder, such changes are too unimportant and too undefined and unspecific to be considered as causes. Others aver that they have never examined the brain of a GENERAL PARALYSIS. 169 patient avIio has died insane., without detecting some morbid alteration of the brain or its membranes ; and these authorities are certainly amongst those Avho have had opportunities, not by units or tens, but by hundreds of cases. Again, others affirm that the Ausible and palpable changes are certainly in many cases deficient, but would, doubtless, be revealed were our means of investigation by the microscope and by chemical analysis more perfect. And, in addition to all this variety of opinion, it has to be taken into account that Avhat- ever may have been the proximate cause of the mental affec- tion, certain additional, physical changes must have taken place in order to cause death; and there is the superadded difficulty of deciding what has dethroned reason, and Avhat has destroyed life. In short, we are still ignorant of Avhat may cause mental aberration, and what is its essential, mate- rial element; nor have we as yet obtained any certain start- ing-point, any positive data Avhereon to found a clearly inductive system of research. One of the principally con- tested points concerning this affection is, whether it is essen- tially connected or not with mental disorder, for it appears to occur sometimes entirely independent of mental affection ; sometimes to supervene upon it; and sometimes to precede it by months, or perhaps years. The causes of general paralysis are immediate and predisposing. The former are such in gen- eral as produced prolonged over-excitement of the brain, — sensual excesses, especially the abuse of intoxicating drinks, over-feeding, sexual indulgence, and intellectual excesses, accompanied by prolonged vigil. The predisposing causes may be considered to be such as belong to insanity and brain affection generally ; the disease moreover attacks men much more frequently than Avomen, and both chiefly between the ages of thirty and forty-five years. The symptoms of gen- eral paralysis (of the insane) consist of a non-febrile lesion of the intelligence, the sensibility, and voluntary motion. 170 GENERAL PARALYSIS. The intelligence is constantly affected from the commence- ment of the malady. Sometimes only observed as a feeble- ness of memory or judgment; and most frequently, as mania with the delirium of grandeur and poAver; sometimes as melancholia, and sometimes again, as simple dementia from the outset, a condition into which all the previous forms have a tendency to merge, as the disease makes progress. What- ever may be the original specific type of the mental affection, the faculties are observed to be enfeebled progressively even during the excitement of the opening delirium ; and this goes on until the last phase is characterized by the utter extinction of all intelligence. The alteration consists in progressh'-e weakness of the voluntary movements, commencing by trem- bling of the muscles of the tongue and mouth, by a more or less marked difficulty in the pronunciation of Avords, and afterwards by hesitation in walking and uncertainty in stand- ing, with trembling and weakness of the hands and arms. The loss of muscular power extends often, and especially in the later stages, to the sphincters of the bladder and anus. When arrived at the extreme, the loss of power condemns the sufferer to absolute immobility and muteness. The loss of sensibility has not been studied with the s,ame amount of care and attention as has been bestowed on that of motion and intelligence. Yet it is ascertained that the general sensibil- ity is notably diminished, and the sense of touch greatly deteriorated. The sight and hearing partake in some meas- ure in the general dulness of sense. The seat of the malady is in the cortical layer of the cerebral hemispheres. The progress of the development of this affection has certain characters which are special* to it, as relating to the connec- tion and succession of the symptoms, and the termination of the disease. Impairment of the memory and judgment is evident from the first, and continues always increasing until their entire abolition. One of the most special and distinctive GENERAL PARALYSIS. 171 as well as most serious characters of general paralysis is that it terminates constantly by death. As we proceed, we may find some exceptions to this in the general paralysis occurring independent of mental disease, but most observers agree, that Avhen once general paralysis has appeared, even slightly, in an insane person, there may possibly be a remission of symptoms even for a considerable period, but there can be or rather has been hitherto no cure, — death is imminent and certain, although at a very uncertain period. Perhaps the average duration may be from two to three years. It is very common before the close of life to observe gangrenous sloughs in all parts of the body that are exposed to pressure ; the phenomena of life are merely vegetative for some time before dissolution. It is very common to see patients who have gradually fallen into dementia without presenting any of the symptoms of reaction or delirium, or in whom these have been extremely slight and subordinate. As this decay of the intelligence is established, Ave notice at first slight, and then more marked signs of paralysis; and shortly we have developed a paralytic insanity so marked, that none can mis- take it. By the side of this numerous group there is another Avhich is yet more so, especially amongst men. The patient beo-ins by presenting the signs of an excitement more or less lively ; he moves about perpetually, and cannot remain still for a moment. At the same time he forms large projects, buys all manner of objects, gets angry when opposed, and cannot sleep. To this state succeeds a complete maniacal delirium, Avith predominance of ambitious ideas, and a special muscular agitation quite distinct from that of ordinary name. At the same time, if Ave are in the habit of attentively observ- ing such patients, Ave shall detect a little hesitation in the pronunciation of certain words. Such are in the two groups which are at present designated under one name, that of insane paralysis. These symptoms are assuredly very much 172 GENERAL PARALYSIS. opposed. In the one case we see debility, inaction, and the slow extinction of the cerebral functions ; in the other, force, violence, and an increase of physical and intellectual activity. Authors have related a few cases of recovery, even after the patients had presented the gravest symptoms of paralysis; and that although these facts may be considered exceptional, they are doubtless of the highest significance. Observation 1st,—Mania for some months, Avith predominance of ambi- tious delirium; very marked symptoms of paralysis, with difficulty of walking and standing. Stammering not present, but some hesitation occasionally before a word. Formation of gangrenous sloughs, followed by recovery, Avhich lasted twenty-five years. Observation 2d, — M----, aged forty- one, had some insane relations, and became melancholic him- self after some domestic trouble. He had some epileptic attacks; the speech became imperfect, and one arm Aveak. After his entry into the asylum, he was in continual agitation and had the delirium of grandeur and riches fully developed. Pupils unequal, tongue furred, pulse accelerated. The sen- sibility became very much diminished, and the paralysis extended to sphincters. He could not Avalk nor write his name ; there appeared a great number of sloughs on the body, some apparently Avithout cause, some where his agitation had bruised the skin. After attaining almost the lowest state of paralysis, he began to recover, — as it is stated not by means of therapeutic agency, — and both his reason and his bodily poAvers returned. He was alive and Avell when the account was Avritten, ten years afterAvards. (From the " American Journal of Medical Science.") Ob- servation 3d,—General paralysis, apparently of the worst kind; symptoms of the last period. Acute oedema of one leg, with gangrene. Rapid recovery which is known to have lasted six years. Observation 4th, — Acute mania, with ten- dency to ambitious ideas; feebleness of the memory, uncer- GENERAL PARALYSE. 173 tain walk. Eruption of boils Avith abundant suppuration, embarrassment of speech ; recovery. Duration of the malady, one year. Duration of the recovery, five years. Sudden death from cerebral haemorrhage. The fifth case recovered after an abscess of the liver ; the sixth after a purulent dis- charge from the ears ; and the eighth after an amputation, fol- lowed by profuse suppuration. In all these cases the paralysis was so far advanced as to be unmistakable ; the authorities from Avhom they are quoted are unimpeachable. We must therefore admit the possibility of paralytic ambitious mania being cured. As for remedies : moderate local bleedings, says Pinel, at the outset only, and when there are signs of congestion, — issues at the base of brain, repeated vesications over the scalp — general affusions, and ' revulsives from the intestines and extremities, are the principal means to be used. There are well authenticated cases of recovery. I am convinced, says Pinel, that general paralysis is not a disease especially appertaining to the insane ; that it is not a form of insanity ; that it does not necessarily and fatally induce it; that it is an affection independent of this latter, so long as the alteration which produces it does not extend to that portion of the molecular structure of the brain, which presides over intelligence ; and I believe that this portion of the brain may escape lesion during the whole period of life. The question of the essential nature of general paralysis has perhaps been complicated more than by any other con- sideration, by that of the Arariety of manners in Avhich it makes its first appearance. We Avill briefly sketch three. General paralysis presents itself in four forms, two of Avhich are marked by bodily disorder, and tAvo by mental. 1. The paralytic variety. This is the most insidious of all the forms in Avhich this fearful disease appears, and has perhaps given rise to more contest as to its nature than any other. For some time the only disorder appears to the ordinary observer 174 GENERAL PARALYSIS. to be one of the motor functions exclusively. The patient himself perceives that his actions become irregular, trembling, and Avanting in precision. He lets fall objects which he holds in his hands, and cannot perform any acts which require delicacy of manipulation ; writing, drawing, or playing on any instrument becomes difficult. He stumbles against the slightest obstacle, and Avalks with a jerk ; he is more quickly fatigued than formerly, and all his motions lack co-ordina- tion. All this, which comes on very slowly and impercepti- bly, is accompanied from the outset by a peculiar hesitation and embarrassment of the articulation, or stammering. Ordi- narily there is a slight pain in the head, and dizziness, an unequal dilatation of the pupils and not unfrequently genital impotence, with occasional incontinence of urine. During this period the patient is conscious of his failing strength, and troubles himself about it. He appears at first to enjoy the full exercise of his faculties ; but although in some rare cases it is not possible to detect any intellectual Aveakness, in general the practised observer will recognize some indication of this. There is an undefined alteration of character or disposition, a mobility of temperament that scarcely admits of descrip- tion, the performance of odd, bizarre acts that pass for eccentricity, a tendency to make mistake in his usual employ- ment, a slight weakness of memory for recent events, and, what is the most serious symptom of all, a combination of a marked hypochondriac tendency, with a general feeling and expression of satisfaction and pleasure, the sure forerun- ner to an outbreak of the expansive ambitious maniacal delirium, Avhich is not then long delayed. 2. The congestive variety in this form, the physical symptoms again predomi- nate over the psychical. The predominant character is one of transient and recurrent congestion of the brain with or Avith- out loss of consciousness, ordinarily slight, though some- times very severe, simulating apoplexy or epilepsy, and GENERAL PARALYSIS. 175 giving rise to the opinion that the subsequent paralysis has been caused by one of these affections. This form of conges- tion is distinguished from the ordinary apoplectic form, by leaving more serious and persistent traces in the moral and physical nature. The speech remains for a longtime disor- dered, the movements of the limbs become difficult, and sometimes there is even incomplete hemiplegia, which dimin- ishes and disappears sloAvly, to return perhaps after the next congestion. The intelligence is affected after each attack, as Avell as the motive poAvers ; but if there be any consider- able interval, both orders of phenomena partially disappear, and the patient is restored to a comparatively healthy condi- tion; apparently, immediately after the attack Ave may detect a considerable feebleness of memory and the other faculties ; but in time the intellect appears to resume its ac- tivity. After several attacks, hoAvever, both the physical and intellectual nature is found to be unmistakably deteriorated, and dementia, accompanied by various forms of delirium, supervenes. In short, like the last form, the malady assumes the ordinary aspect of " general paralysis of the insane." Melancholic Variety. —In this form the psychical disorder first attracts the attention. It is only in comparatively rare instances that the physician sees the first stage of the malady ; but in inquiring into the history of paralytics, he Avill not unfrequently find that the first phenomenon that attracted attention Avas a state of marked moral and physical Aveak- ness or depression, Avith lowness of spirits, and incapacity, real or supposed, for any form of action; presenting every appearance of hypochondriacal melancholia. Even at this period there may sometimes be detected slight disorders of mobility, as stammering or hesitation in speech, or feebleness and trembling of the limbs. But these symptoms are over- looked, the melancholia absorbing the Avhole attention. The melancholic period may be very short, or it may have 176 GENERAL PARALYSIS. lasted some time ; but in all cases that are paralytic it disap- pears gradually, to give place to the normal condition. But this is very transitory; almost as soon as the signs of mel- ancholia begin to disappear, the attentive observer may detect frequently the symptoms of an opposed condition. The patient experiences a sensation of exaggerated comfort; he Avas never so well in his life, body or mind ; he begins to be unnaturally active, moving incessantly ; he forms projects of Avhich he Avould never have thought before, perhaps not absurd, and altogether out of accordance Avith his fortune or profession, but still quite opposed to his previous habits and tastes. He then either passes gradually into the true expan- sive delirium, or a fierce mania Avith predominance of am- bitious ideas breaks out suddenly, after Avhich his history is the same as that of the next variety. The expansive Variety. —This is the most frequent form of the debut of general paralysis ; and from the marked char- acter of the symptoms clearly requiring immediate attention, it is more frequently noticed in its earlier stages than any of the others, and on this account has been erroneously supposed absolutely essential to the character of general paralysis. Those paralytics who present themselves from the outset with the expansive form of delirium, have been ordinarily men of active minds and habits, enterprising, rash, and gen- erally of irritable, violent character, with much generosity. The expansive delirium is an exaggeration of this character; and so gradually does it sometimes* sweep on, that the mo- ment of actual outbreak is difficult of detection. The patient appears at first to be simply more active, more rash, more irritable, and by fits and starts more generous and lavish in his expenditure than before. By and by all this passes clearly beyond the normal state. The subject is in perpetual motion, takes no rest, cannot sleep, feels an exag- gerated sense of poAver and general well-being, and conceives GENERAL PARALYSIS. 177 projects of the most stupendous character, that must be at once carried out, all of Avhich, if not quite irrational, are opposed utterly to his previous habits and tastes. He adopts excesses which are not habitual to him, passes an irregular and disorderly life, and commits acts which greatly astonish his friends, such as undressing in society, sleeping in the fields, and out of his own house, and perhaps committing petty thefts without any motive. He is possessed of bound- less Avealth or poAver with Avhich he will perform the most unheard-of deeds. He Avill give away his property, and if he has none he will profess to do so. He is endoAved with supernatural attributes, he is God's vicegerent upon earth, he is some mighty potentate. Acting upon some of these convictions, he commits an offence against society, himself, or property, which demands his seclusion, when the true nature of the case is readily recognized. CHAPTER XXII. DIPSOMANIA, OR DRUNKEN INSANITY. This is a learned word Avhich signifies an insane thirst, a moral insanity in regard to Avines and liquors. A man is a drunkard who gets drunk at the festive board, who seeks occasions for getting conveniently drunk without interfering with his ordinary occupation, who takes a feAv days drinking at a time when he has plenty of money, and returns to his duties and employments when he has finished his superfluous cash and his "bender" or "spree," as it is called. Some men, on the other hand, get systematically and regularly drunk every day after dinner, some every night before going to bed, and will perform their daily duties Avith propriety and efficiency. Obviously they do not come under the head of insane drinkers, for they exercise a certain amount of self- control, a sufficient amount of restraint upon their appetites, not to alloAV the quantity Avhich they drink to affect their aptitude for business, or driving a good bargain. The prin- cipal feature of this disease — that of insane drinking, or dipsomania — is, on the other hand, the absence or loss of the poAver of self-control or self-regulation. Persons affected Avith this form of moral insanity do not drink from the pleas- ure which the social board affords, but, on the contrary, will not unfrequently preserve a certain amount of decorum while in company. Neither do they drink for the pleasure [178] DIPSOMANIA, OR DRUNKEN INSANITY. 179 which the Avine gives them ; they will drink any kind of intox- icating stuff. Nor do they drink at a convenient time and place, and only occasionally ; they drink as often as they can, and as much as they can ; their craving for stimulants is inces- sant and uncontrollable; no considerations of self-respect, no regard to public opinion, or common decency, or domestic ties, or religion, or the certainty of impending ruin, degra- dation, or even the fear of death, can prevent their drinking till they can drink no longer. Such persons Avill often deplore their fatuity, their inability to control their appetites, and will say with tears in their eyes, as some have done, that if hell Avere yawning at one side of them, and a bottle of brandy standing at the other, they would drink, although the next moment they Avere to be thrown into the bottomless abyss. In a word, such persons drink because they cannot help it, and if they really cannot help it, they must be reo-arded as no longer responsible agents, — as, therefore, insane, and proper objects for being restrained and protected against themselves. The loss of self-control is, indeed, the most essential condition of almost all cases of insanity. The most constant symptoms of insanity are those referable to altered affections, perverted desires, and morbid propen- sities. In almost all cases of this variety of moral insanity there is a total disregard for truth. Such persons are singu- larly mendacious. They Avill resort to every possible device to procure stimulants, to excuse their conduct, to deceive their friends and medical attendant, will display an ingenuity and fertility in deceit which is truly marvellous. They Avill become faint, or be in agony with the toothache, or tic, or cramp in the stomach, or colic, etc., and represent them- selves at death's door in order to get brandy, wine, or opium administered. They will pawn every available article of dress or furniture or jewelry. They will borrow from all and sundry. They will get whiskey smuggled home Avith 180 DIPSOMANIA, OR DRUNKEN INSANITY. their clothes from the tailor or laundress. They will evade the most vigilant surveillance, and tell the most deliber- ate falsehoods in their attempts to deceive, solemnly appeal- ing to God for their truth. When shut off from the ordi- nary sources of stimulation, they will sometimes resort to almost anything to relieve their craving. I have known a young and delicate lady, after being prevented getting Avine or spirits, and deprived of lavender wTater and eau de Cologne, take creosote, vinegar, tobacco. Again, such persons will insist on a total denial of their habits of over-indulgence. They wall very frequently disavow most solemnly having ever exceeded the bounds of strict tem- perance in their use of stimulants ; and, if admitting at all that they have ever been the worse for drink, they will blame some other person or circumstance as the cause of it. Accompanying this disregard of truth, there are often other indications of moral perversion in the insane drunkard, such as extreme licentiousness, or a propensity to theft. The disease is frequently hereditary; and it will be found, on inquiry, that a grandfather, or father or mother, or one or more brothers, have died of delirium tremens, orhaveother- Avise shoAvn the fatal propensity. The constancy with which the hereditary predisposition to this disease is transmitted is most remarkable, and, in a vast majority of cases, can be traced either through the the maternal or paternal side of the family. To illustrate the truth of these remarks, I have ana- lyzed the records of eighty-six of the cases of this form of moral insanity which I have had under my care, of AA7hich tAventy were females and sixty-six males. Of the former one half presented natural peculiarities in their mental constitu- tion, being either of Aveak minds, of very violent and uncon- trollable passions, or subject to hysterical attacks of great violence, combined in some instances with great moral depravity. Of the males, thirty, or nearly one half, were DIPSOMANIA, OR DRUNKEN INSANITY. 181 naturally of Aveak mind, or presented some mental peculiar- ity, such as silly vanity, general depravity of disposition, and, in some cases, considerable talent, but combined Avith eccentricity. In regard to hereditary predisposition, it is difficult generally to trace this in a public hospital, partly because many cases come in without any information regard- ing them at all, and partly because the friends, Avhen they have friends, are generally very solicitous to deny or conceal the existence of an hereditary taint in the family. Of this malady there are three divisions, the acute, the periodic, and the chronic. Under the head of acute, I would include all those cases of uncontrollable drinking Avhich occur to persons of previously temperate or regular habits, but in Avhom this insane craving has been generated under the influence of some accidental cause, — such as the noArelty and excitement of a new sphere of duty, and the temptations of neAV asso- ciates and habits, all combining to lead to intemperance ; or the depressing effects of some overAvhelming calamity, or of some debilitating accident, or disease, or other agency. It is Avell known that the use of stimulants, begun or indulged in under any of these circumstances, has gradually merged in many instances into an inordinate and uncontrollable craAano-, and an insatiable and destructive use of them. Cases of this kind, if taken in time and treated judiciously and firmly, are generally curable Avithout recourse to any step for depriving the patient of his personal freedom. Periodic or recurrent attacks of this disease are generally dependent upon some constitutional or hereditary peculiarity. Some- times they occur at the critical age in females, and preserve a periodic form coinciding with the menstrual period. Some- times they arise from injuries of the head. Cases of this kind are less easily treated than the acute, particularly Avhere there is a hereditary predisposition. They hardly justify confinement. The uncontrollable impulse will come at 182 DIPSOMANIA, OR DRUNKEN INSANITY. its accustomed time. Nor does this form of the disease inter- fere materially, in many cases, with the duties of life. Many individuals have distinguished themselves in literature or in professional or mercantile life, who have been known for a long term of years to retire periodically into the pri- vacy of their oavii chamber, and, after indulging this morbid appetite to satiety for a week or two, in their voluntary seclusion, to reappear again on the stage of life, and pur- sue their usual avocations with credit and success. Such cases are perhaps rare, and more frequently it happens that the periodic or recurrent form gradually degenerates into the chronicWariety of the disease, the intervals becoming shorter and the attacks longer, until the intervals cease altogether, and a chronic disease or* a fatal issue ensues. It is the chronic form of this disease which is the least curable and most troublesome to manage. Hero the craving for stimu- lants, brought on perhaps by indulgence and irregular habits operating upon a constitution hereditarily predisposed, becomes constant, insatiable, and incontrollable ; and the daily or hourly indulgence suffers only now and then a tem- porary check by illness caused by it, by attacks of delirium tremens, or outbursts of mania. I believe it is agreed by all parties, that this form of the disease can only be treated effectually by prolonged and complete abstinence from all stimulants. CHAPTER XXIII. LATE SUPPERS AND DREAMS. We have alluded to the subject of the effect of late suppers on the nervous system already. A late supper is an unwhole- some meal from whatever point looked at. The influence both of food and drink on the mind is acknowledged. A man may be said to think according as he eats and drinks. Every- thing Avhich affects the circulation of the blood, or which in- creases or diminishes the nervous force, may and does interfere Avith, modify, or stimulate the action of the mental faculties. Dreams merely indicate a disturbed condition of the stomach or brain. I can best illustrate this subject by relating some curious dreams in point, dreams Avhich have been occasioned by food Avhich has disagreed Avith the digestive organs, or Avhich have exercised a peculiar influence upon the nervous system, or Avhich have been induced by food taken at an improper time, or which have happened when sleep has been indulged in immediately after taking food. It is a curious fact that not only the kind of food may determine the events of a dream, but often, also, that the pur- suits of the dreamer will tend to give his dreams some spec- ialty. For example, we knew a medical man who after attending a lecture Avas very hungry, and, contrary to his usual practice, ate a hearty supper of rich fish with a stuffino- composed of liver mixed Avith savory herbs and spices, and [183J 184 LATE SUPPERS AND DREAMS. some stimulating sauce. When he Avent to bed he had a rather dry and feverish skin, but he soon fell asleep and dreamt the following curious adventure : He said, "that he thought he AA^as travelling in a very hot country, Avhich abounded with a number of poisonous serpents, particularly the ' cobra di capella,' and that, having the opportunity to dissect some of them, he seemingly did so Avithout harm to himself, until he proposed shoAving the structure of the secretory glands, Avhich generated the poison. These he traced to the loAver surface of the tbngue, and when in the act of carefully pressing these glands to ascertain the color of the deadly fluid, a little of it squirted into his face and caused him great pain. The sense of his dangerous position awToke-kun,and he was highly gratified to find merely a little eruption on his nose and face, evidently caused by the rich food of which he had partaken the previous night," and he added that indigestion Avas iiwariably relieved in his own case by eruptions on the skin. We select another instance to prove that particular food not only gives the. specialty of the dream, but also iu this case revived impressions of the past, and gave them all the vividness of reality. The person said, " The other liio-ht I Avas very hungry and Avas induced to eat supper, and added to the outrage of partaking of cold roast beef, the folly of eating about a dozen pickled onions. But as I felt very com- fortable and had a long Avay to walk, there was not any mis- giving that for so doing any great punishment Avould result. By the time I reached home it Avas at least two if not three hours after taking the uiiAvholesome meal, and soon after- wards I went to bed. I felt someAvhat uneasy, but it Avas not long before I fell asleep. Soon afterwards I dreamt that for some offence of etiquette I was doomed to eat ' sour-crout.' Noav it so happened that this kind of pickled cabbage ahvays caused me most painful nausea even Avhen smellino- it LATE SUPPERS AND DREAMS. 185 so that I had never been prevailed upon to taste k. Never- theless, in the vision, it seemed that great pains and penal- ties aAvaited me, unless I abided by the unchangeable fiat of the judges. 'I fancied myself brought into a large room in the centre of Avhich Avas the reeking crout, and Avhat with its acid fumes and its fatty smell I was almost overpowered, and I experienced a sense of nausea and disgust. Still I made the effort to eat, but every mouthful which I endeavored to swallow was immediately rejected, and the painful and sick- ening sensation increased at every attempt to retain the abominable stuff. My situation was indeed pitiable; and the perspiration trickled doAvn me, from the agony I experi- enced. It Avas a battle betAveen sour-crout and the stomach, and the struggle Avas desperate; but the stomach conquered, and I aAvoke. My mouth was filled Avith acidity and the disagreeable taste of the onions, which together rendered my sensations most unpleasant. This condition of the mouth had evidently suggested the dream, and an early* antipathy for fermented sour cabbage was reproduced with as much vividness as if the crout had been positively served up, and coercion had been used to enforce it being eaten." This individual was advanced in life and had not seen or smelt the sour-crout since his boyhood, yet its odor appeared as disagreeble to him in his dreams as it would have been in his wakeful moments. Here is a somewhat funny dream which occurred during not a late supper, but an after-dinner nap. A gentleman fond of good living, aat1io invariably did justice to his meals, one day had dined at home Avith his family, aud being very hungry, he had despatched slice after slice of some roast or boiled mutton, declaring that he had never eaten a more delicious, juicy, tender specimen of mutton ; and as a proof of his sincerity, he refused all the et-ceteras of a wealthy citizen's dinner meal. After dinner he took his usual short siesta. He had been but a short time asleep, 186 LATE SUPPERS AND DREAMS. when he began to laugh, and that so heartily, that it was con- tagious, and the risible chorus soon awoke him. Imme- diately all asked him Avhat he had dreampt about that had so tickled his fancy. " Well," he replied, " I thought that I was at a public dining-table, at which there were many stran- gers. The tables Avere Avell supplied Avith fish, meats, and vegetables of all kinds in season, and I myself only partook of mutton. But what tickled my fancy in the first instance was, that I oArerheard the Avaiters speak of the different vis- itors, giving each the name of the ' dainty dish ' he or she had preferred. There were Mr. Fish, Mrs. Steak, Miss SteAv, Lady Cabbage, Mr. Rice, Miss Duck, Old Squire Bread, and numerous others distinguished by what they most enjoyed. I thought it curious that I had not been mentioned, and prob- ably I should not have been, had not one of the ladies asked my name, ' O, ' said the domestic addressed, ' you mean Old Mutton.' This audible reply was not considered rude, as he had feigned deafness. He thus became the topic of conversation. ' Old Mutton is a curious, eccentric person- age,' observed a sly fellow, who with a most beAvitching lisp proposed Old Mutton's health and ' let him know our admira- tion is excited,'said the speaker, 'because he sticks so loAr- ingly to his family connections, and gives them the preference, as Ave all have witnessed.' All the company rose simul- taneously, and turned towards me, then Avith mock gravity boAA^ed, saying, ' Old Mutton's good health.' Whilst a feAv, not improved in their manners by Avhat they had drunk, shouted out, ' Here's to jolly Old Mutton.' Then I opened my eyes and stared at them, and thus addressed the com- pany: 'Thank you, my innocent lambs, but you bleat most discordantly.' The surprise that Avas depicted on every face looked most ridiculous, and I continued in a strain of badi- nage. * Well, you pretty innocent, Avool-covered creatures, I am very glad you are not foxes, or else " Old Mutton," LATE SUPPERS AND DREAMS. 187 " Jolly Old Mutton," would have had little chance of saving himself from your chops ! " All this and much more had taken place during a doze of a few minutes. Here is another amusing dream, suggested by the nerves of taste Avhich occurred to a lady, a friend of the writer, and which furnishes some speculative thoughts to the psychologist. Mrs. —had a slight cough, and one of her daughters brought her some barley-sugar to suck when in the act of lying dovai, or in case the cough disturbed her during the night. She had on the occasion avc are about to relate, taken a piece of this SAveet medicine into her mouth, and soon afterwards fell asleep AAdth the confection undissolved. She dreamt that she Avas a very little girl, and that she Avas spending the even- ing in a juvenile party, at which, besides tarts and jellies, there was added an abundance of sweet-meats of the most delicious kinds. She felt superlatively happy, and, Avhat contributed to ensure this satisfactory state, all her early associates wrere present. These friends of her childhood appeared the same laughing girls and boys, and Avere appar- ently undisturbed by care or annoyance of any kind. Yet she seemed to have some undercurrent of misgiving, for many of these spectra had been dead for years, and others she had not seen since their school days, Avhen she herself Avas but a little girl. But these reflections did not affect her; for she fancied herself entering into all kinds of childish sports and pastimes wdth all the glee imaginable, and so she continued to laugh Avith those around her until she aAvoke with a smile on her features ; and so brief Avas the Avhole period of the dream that her daughter had not left the bed- side, for she had not been asleep more than a few moments. The explanation is, that as she Avas going to sleep the passing idea occurred : "lam like a little child, to go to bed with SAveet-meats." This suggested to her mind the train of pleasing thoughts. For when the world was closed on her 188 LATE SUPPERS AND DREAMS. unconscious senses, the soul thus untrammelled revived the scenes of her juvenile days, and called forth from the shadowy past her former associates, companions who had been forgotten during her maturity, with its hopes and fears. CHAPTER XXIV. THE USES AND ABUSES OF THE POPULAR NERAaNES. Particular kinds of remedies and medici • s, like other things, are at particular times all the rage, and are supposed during their brief period of popularity to be absolute cura- tives for the particular class of affections and ailments for which they are designed. Of course in this high-pressure age, wahen nervous affections and nervous diseases of all descriptions arc the preAralcnt ills of the flesh, at least among all those classes Avho employ head-Avork, Avhether professional, literary, or mercantile, nervous remedies are in especial demand. The danger is that Avhen a particular remedy becomes thus popular, it Avill be used in excess, and so, in the end, prove detrimental. For instance, there Avas a time Avhen prepara- tions of mercury were all the rage, and when it Avas supposed that such preparations were actual panaceas or cure-alls. The consequence Avas that mercury was not only used prop- erly, but misused and abused, until it has become a synonyme of all that is deadly as a medical prescription. So with bleeding, it was regarded as such a sovereign remedy at one time, that a physician who visited a patient without his lan- cet, Avas thought to be Avithout the means at his command to properly practise his profession. And cupping Avas practised to such an extent, that the last dregs of the cup of human [189J 190 USES AND ABUSES OF POPULAR NERVINES. life Avere in danger of being drained. So hydropathy had its run, andAvas esteemed at one time a sovereign remedy. So at the present time, which may be called the era of nervous diseases, there are certain fashionable nervines which are mis- used and which are abused to full as great if not to a greater extent than calomel, phlebotomy, and the cold-water pack used to be. The Avriter has recently had a nervous patient Avho, by the excessive use of belladonna (deadly nightshade) injudiciously prescribed by a friend, evidently Avith the best intentions, became so addicted to the inordinate use of the drug, as a nervous remedy, as to induce amaurosis and come near a total loss of eyesight. It is well known that chloral is a poAverful hypnotic (or sleep producer), and wakefulness being one of the most distressing symptoms and incidents of nervous diseases, this remedy Avas naturally hailed as almost a benison from heaven, and became in literary and fashionable circles, in all cases Avhere, either through ill health or over-indulgence, the nerves Avere unstrung, a universal resort as a prescription. The consequence was that the patients using this powerful remedy, not taking into consid- eration the reaction Avhich inevitably follows, became inca- pable of any but an unnatural, artificially induced sleep, AA'hich only continued during the effect of the druo\ Iu short, healthful, ordinary slumber became an utter stranger to their pilloAvs, while phantasies and disturbing visions of all kinds continually haunted their nocturnal hours. There is another class of nervines, which have come into great use and celebrity Avithin the past ten years, Avhich deserve espe- cial mention and consideration. I allude to the multitudi- nous salts of potassium, prominent amongst Avhich are the bromides and iodides. This class of nervine remedies has of late been considered the great resource in the treatment of nervous affections, particularly in cases of cerebral congestion or irritation of the base of the brain and spinal column, USES AND ABUSES OF POPULAR NERVINES. 191 and in gastralgia ana dyspepsia or inflammation of the stom- ach, either acute or chronic. Every patient suffering from hysteria, alcoholism or delirium tremens, melancholy, de- spondency, or venereal excesses, has been liberally dosed with bromide of potassium. While I do not wish it to be inferred that I entirely ignore this class of nervous remedies, or deny their utility and beneficial effects Avhen judiciously administered, I still must insist that these remedies should never be administered alone, or in quantities Avhich may be well termed excessive, as the invariable result of such im- proper administration is a depression of the nervous system, from AArhich the patient seldom if ever rallies. Furthermore, it is a well-known therapeutical fact that bromide of potas- sium produces a permanent aneemia (or absence of blood) in the brain throughout the Avhole capillary and arterial cir- culation. Consequently, as must be evident eYen to the un- professional reader, if its use be continued the result is con- tinued until the brain, deprived of nutrition, loses its tonicity, and softening is the inevitable consequence. No more terrible affliction, of course, can befall a human being than this. Henceforth he Avanders about a lack-lustre idiot, until death comes to his relief, much, also, to the relief of his friends. In 1812 aconite was introduced as a nervous sedative by Sir Benjamin Brodie. The peculiar action of this drug upon the nervous fibre is due to the alkaloid, Avhich does produce a very rapid and tranquillizing effect on the brain, at the same time also producing a very depressing effect on the heart and circulation. In other words, the brief beneficial effect of the administration of the drug in quieting the brain is secured at the expense of the permanent depression of the nervous system. The administration of this drug, when persisted in, is almost sure to produce apoplexy. Where there is too much tone, excessive tension of the nerves is a result, and when there is too much depression, effusion is 192 USES AND ABUSES OF POPULAR NERVINES. pretty sure to follow. Even the small doses of this drug prescribed by homoeopathic physicians finally induce the same results as in a more heroic practice. I wall close this cursory discussion of the merits and demerits of some of the popular nervines by a word or two about the most com- mon and popular of all the nervines (for a nervine it is to all intents and purposes, and not by any means perfectly harmless), to wit: Tea, one of the chief constituents of this beverage "which cheers but not inebriates," is tannin, a substance so poAverfully astringent as to produce derangement of the liver and all the excretory organs. Hence the exces- sive use of tea is oftentimes at the bottom of the complete derangement of these organs. As a result, come spleen, melancholia, and nervous derangement. As for the other nervines, such as valerian, morphine, lactucarium, hyoscy- amus, etc., they all have their devotees, and are too well known, both in their curative and pernicious effects, to need special notice. Suffice it to say that all the nervines are necessarily perilous agents, except in the hands of a skilful practitioner, who has made nervous affections a life-lono- study and specialty of treatment. INSTRUCTIONS TO PATIENTS. Dr. Hayes, having for many years devoted his attention to the treatment and cure of diseases of the Nervous System described in the preceding pages, may be personally consulted, together with Dr. Parker, his assistant and former pupil, from nine in the morning until six in the evening, daily, Sundays excepted, at his office, No. 4 Bulflnch St., Boston, Mass. Cases can be treated by correspondence when a personal interview is im- possible, providing the patients will minutely detail all of their bodily infir- mities and mental disturbances, written in a simple and natural style, and in accordance with the unerring dictates of their own feelings. One personal interview, however, even with patients resident at a distance, is highly de- sirable Avhen practicable, and will more than repay the patient the expense and trouble of a visit to Boston. The advantages of such a visit are apparent and manifold. A single visit in most cases will enable the Doctor to form an accurate opinion and note particulars which might be lost sight of in mere correspondence, particularly when a microscopic and chemical examination of the urine is absolutely necessary. Patients not Resident in "the City, Who wish to transact their business through the mail, or by express, can have their necessary remedies sent to any address, or left at any railway station or coach office in the United States or Canadas until called for, care- fully packed and securely sealed. All communications must contain the usual consultation fee of five dol- lars ; otherwise no notice will be taken of their application. A distinct name and address is necessary. Money can be forwarded by enclosing bank notes in a registered letter, to ensure their safety, by Postal order, drafts on New York or Boston banks, or by express. The entire correspondence of the Institution comes under the personal inspection of Dr. Hayes, whether addressed to the Peabody Medical Insti- tute Dr. "W. H. Parker, his assistant, or himself. [193] TESTIMONIALS. By way of conclusion to this volume, the author is gratified to be able to place before his multitudinous readers a number of cer- tificates and testimonials of his success in the cure of nervous diseases from grateful patients residing in different parts of the country. These testimonials have been unsolicited, and are such tributes as would be flattering even to the most distinguished mem- bers of the medical profession. Naturally enough, patients who have been cured of the most depressive class of ailments and ills to which flesh is heir, are somewhat warm in their expressions of gratitude towards their medical benefactor. The writer could fill a volume with authentic testimonials of a similar nature. Man}- of these testimonials are from prominent and influential persons in the various localities in which they reside, — from persons, in short, in all avocations of life. AN ALMOST HOPELESS CASE OF NERVOUS DISEASE. Perfect Cure. — A Grateful Testimonial. Boston, May, 1873. In June of the year 1865 the undersigned went to California and took charge of a large mining interest, in which his own fortunes, as well as those of several friends, were largely involved. The interest was in litiga- tion, and for a year and a half was under the constant strain of intense mental anxiety, to say nothing of incessant bodily activity. My manage- ment was successful; but at the end of a year and a half I found myself [195] 196 TESTIMONIALS. completely prostrated and broken down by excessive mental and bodily exertion. I was, in fact, the subject of one of the most serious forms of nervous disease, caused, I was told by the medical authorities, by conges- tion of the base of the brain. To be thus suddenly arrested in the very midst of a lucrative and most promising enterprise, just when I had reached blue water, as it were, and all difficulties had been overcome, and doubts of success had been dispelled, — to be arrested, I say, at such an interesting juncture by an alarming ner- vous affection, which completely incapacitated me for any mental or bodily exertion whatever, was sufficiently discouraging and disheartening. It was like drowning, not only in sight of land, but with one's clutch on the shore.. It was useless to struggle. I was obliged to succumb; and, by advice of my friends, I went reluctantly east to Philadelphia, where I was placed under the care of a most prominent physician. At this time my memory failed me, and I had lost the perceptions of taste, touch, and smell. My left side was paralyzed. I was constantly tormented by hallucinations and gloomy forebodings as well as by incessant pain, so that a nurse at my side was a necessity that could not be dispensed with by night or day. As I showed no symptoms of recovery, I was taken to Saratoga, that a physician resident there, who was somewhat celebrated for his treatment of nervous affections, might be consulted. Perhaps also it was thought that the mineral waters might be beneficial. I remained six months at Saratoga, not only without amendment of my health, but I had grown worse instead of better. Matters had now become so serious that immediate recourse to the best medical advice and ability to be found in the city of New York was deemed the best step. I was soon under the care of the most noted specialist in nervous disease in the commercial metropolis. After a course of treatment in which electricity formed a prominent feature, my friends were notified that my case was hopeless. There was life left in me, it is true, but the verdict was that there was no hope. Henceforth I was to be a burden to myself and my friends, until death came to my relief. At this critical point an eastern gentleman, who had business with one of my friends in New York, happened to be informed of my hopeless con- dition. He called to see me, and strongly advised that I should be taken to Boston for a personal interview with Dr. Hayes, the consulting physician of the Peabody Medical Institute in that city. He was told that I had been taken from place to place for medical treatment several times already with- out receiving the least advantage, and that another removal to a distant point would probably result in another failure to obtain relief, and would therefore be worse than useless. But the eastern gentleman, being of a sanguine temperament, would not give my case up so, and finally prevailed upon those who had me in charge to take me to Boston. TESTIMONIALS. 197 Alexander E. Raitt. 198 TESTIMONIALS. After a careful examination of my case, Dr. Hayes said that he could afford me partial relief, but he did not speak encouragingly in regard to a permanent cure. Under no circumstances the doctor informed me could I expect much mitigation of my sufferings from his treatment in a less time than at the end of six weeks. Even partial relief was worth more than a six months' stay in Boston, to say nothing of six weeks. Suffice it to say that I found myself at once subjected to a new treatment, entirely different from anything which I had experienced at the hands of my previous med- ical advisers. It began to tell on my shattered nerves at once, working like a charm. At the end of two weeks the gentleman, who had originally advised my recourse to the doctor, called to see me in my new quarters, and under my new treatment. Sensation had already begun to return to my left side. I was recovering the use of my lost senses, and warmth and motion were taking the place of partial paralysis. The gentleman gave me a L>ak, which said louder than words — "I told you there was hope and cure for you." In fact I felt health dawning anew in me. AA'ith returning strength came hope and confidence, which reinforced the treatment and medicine wonderfully. The doctor acknowledged that he had underestimated the recuperative power of my system. At the end of the six weeks, Avhich he had mentioned as the earliest date of even a partial recovery, he assured me of a perfect cure. His assur- ances were made good by the event. I am at the date of this writing a well man, and have been for several years. Indeed my present occupation requires vigorous health, and I am fully equal to it.' I frequently indulge in gymnastic exercises, and am noted for muscular strength. During my illness my weight, which is now from 175 to 200, fell to 120 pounds. I am induced to write this letter by a sense of duty to others who are suffering as I suffered. It was this sense of duty, combined with a feeling of intense personal regard for my healer and benefactor, Dr. Hayes, which has prompted me unsolicited to pen these lines as a guide to all prostrated with severe nervous disease. I refer to Adjutant-General Cunningham and Judge Abbott, who are personal acquaintances. Alexander E. Raitt. Suffolk, ss. August 1G, 1873. Then personally appeared the above-named Alexander E. Raitt, and made oath that the above statement by him subscribed is true. Before me, T. P. Nuttek, Justice of the Peace. TESTIMONIALS. 199 East Woodstock, Conn., March 8, 1873. To whom it may concern: In the year 1871, my nervous system and phys- ical powers became so reduced by an unnatural drain, and my mind so dis- eased, that my people deemed it necessary, for my protection as well as their own, to send me to the Insane Asylum at AVorcester. I was admitted Edward L. Morse. to the asylum Sept. 12, 1871, and during the many weeks I was confined there, I grew worse, day by day, until it seemed as though I should become a raving maniac, unless I could get relief, which I was sure I could never obtain in that institution. The last of November I managed to escape, and by some mysterious providence I was led to the Peabody Medical Institute, Boston. Dr. Hayes, 200 TESTIMONIALS. the chief consulting physician, and his assistant, Dr. Parker, immediately interested themselves in my case; and after a most thorough and rigid ex- amination, they pronounced my case curable. This I could not realize or believe, my mind being so much diseased; but my father was subsequently convinced of Dr. Hayes's great skill in such cases as mine, and also of the honorable business principles that governed the management of the Pea- body Medical Institute in every particular. He, therefore, at once placed me under the treatment of Dr. Hayes and his assistant. The proper rem- edies were furnished me, and I returned home with my father, where I have remained in safety ever since, visiting the doctor occasionally. The results have been an astonishing change in my condition for the better. I have now been taking Dr. Hayes's remedies for a little more than a year, and con- sider the good results but little less than miraculous. I do not take med- icine now, nor do I need any. When I was forced, or rather entrapped, into the insane asylum, the doctors there pronounced me incurable, — and I think I was incurable at their hands. If this testimonial, which I feel it is my duty to give, should fall under the notice of any sufferer from nervous disease in any shape or form, or from the diseases described in Dr. Hayes's " Science of Life "; or should this be seen by the friends of such a sufferer, I would conscientiously and earnestly recommend them to the author of this book, Dr. Hayes, as a skilful physi- cian and an honorable gentleman. Nor can I do less ; and should any poor, suffering fellow-being wish to make further inquiry, I will with delight give them all the information in my power< Edward L. Morse. Suffolk, ss. March 8, 1873. Subscribed and sworn to before me, Joseph Bennett, Justice of the Peace. Sprlngfield, Illinois, May 9, 1873. Dr. Hayes : Having been under your treatment for the past three months for epilepsy, I take pleasure in saying, in gratitude for kind and skilful attention, that I have derived such essential and marked benefit from your skilful practice as to make me certain that I am cured; at any rate the symptoms of the disease have entirely disappeared, I feel confident not to return. J. S. K. When a person is cured of a disease which, though not generally deemed incurable, is yet manageable only by the most skilful treatment and pecu- liar remedies, it is his duty to those similarly affected to make it known. TESTIMONIALS. 201 For a long period I suffered from chorea or St. Vitus' dance. The action of my brain was disordered and my mind was decidedly impaired. My feel- ings were easily excited and my temper was fretful and irritable. Hallu- nications of sight and* hearing also troubled me. My sleep was disturbed by disagreeable dreams. These mental troubles were accompanied by the usual disorderly muscular contractions. Acting on the advice of a friend who some years ago was cured by your treatment of a like disease, I too placed myself under your care, and after two weeks of constant treatment was radically cured, and the constitutional disturbances entirely disap- peared. I am confident that others similiarly affected with myself, by placing themselves under your care, and following your advice, will be rewarded with like benefit. G. W. P. Richmond, Va., March 3, 1873. Dr. Hayes : Dear Sir: — Gratitude to you for a perfect restoration to health, society, and business, leads me to write you this letter, hoping that you will make it public, so that others similarly affected with myself may know to whom to have recourse for relief. Owing to youthful indiscretions and excesses, I was a sufferer from constant depression of spirits and mental anxiety of the most disheartening nature. Life was a burden and I found myself the vic- tim of hypochondriasis in the very prime of manhood. I found myself also contemplating death as the only refuge from the deep gloom which clouded my life and prospects. At this critical time I was directed to you, and in a few weeks, under your advice and remedies, I became well again, with the buoyancy of spirits natural to health and mental and bodily vigor. J. T. S. Hartford, Conn., Jan. 27, 1873. Fitchburg, Dec. 29, 1872. To the Public: For the good of those affected with paralysis agitatus, or shaking palsy, I am pleased to state that Dr. Hayes radically cured this affection in myself, it being the result of an exhausting disease from which I had suffered. F. N. B. Springfikld, Mass., June 7, 1872. Dr. Hayes: Dear Sir: — Under your skilful treatment and remedies, and by strictly conforming to your advice, and the hygiene recommended by you, I was completely rescued from the horrors of a shattered nervous system, and 202 TESTIMONIALS. made once more capable of complete self-control, so far. as the accursed habits are concerned which drove me almost to suicide. Gratefully yours, A. P. Toronto, Canada West, April 3, 1873. Dr. Hayes: Dear Sir: — I was attacked with what was undoubtedly incipient soften- ing of the brain. Good luck led me to have recourse to you. The terrible infliction was arrested by your remedies, and I am now enjoying good health, and have the use of my mental faculties. It is due to you and the public that I should thus signalize your skilful and successful treatment of my case. R. D. Buffalo, N. Y., Feb. 12, 1872. Friend Hayes : Arduous and unremitted professional labors for a course of years, almost Without recreation, had reduced me to such a state of nervous depression that I was rapidly nearing the dread goal of insanity and complete mental imbecility when I put myself under your treatment. That I have escaped the calamity of a permanently deranged mind, I owe to your remedies, and to the regimen which you advised. Gratefully yours, C E. L. Worcester, Mass., June, 1873. Dr. Hayes: It is with feelings of intense gratitude that I find myself, through the use of your remedies, once more capable of sound, natural sleep. Previously to my application to you for relief, my memory had become impaired. I could not sleep; or if I did, I awoke in a state of excitement and alarm, sometimes in horror. I could not get any sleep for hours after I went to bed. At length this constant insomnia, or wakefulness, reached a point where relief had become an absolute necessity. I could no longer endure the dreadful illusions, hallucinations, and nocturnal visions which haunted what should have been hours of repose, but were not. Learning of your skill and success in the treatment of nervous affections, I had recourse to you, feeling that your advice was a last resort. Nor did it fail me. A few weeks of conformity to your directions, with the use of your prescriptions, have restored me to perfect health. E. W. B. TESTIMONIALS. 203 Dr. Hayes : Dear Sir: — I take great pleasure in saying that your professional efforts in my case of paralysis of the left arm resulted in a permanent cure, and were in the highest degree satisfactory. I am yours, very truly, R. H. W. Syracuse, N. Y. Dr. A. H. Hayes : Dear Sir: — For several years I was the victim of alcoholism, which had been originally induced by convivial habits, and the temptations set before me by the society of numerous and hospitable friends. Almost before I was aware of it, owing to a singularly sensitive and impressible nervous system, I found myself tormented by all the distressing and appalling symptoms and incidents of the above disease. I would have given all I possessed on earth to be relieved from the sufferings aud nervous agitation which ensued. I feel that it is to you I owe my final extrication from the gulf of despair, in which a disposition naturally social and too easily yielding to convivial temptations had involved me. Please accept my grate- ful acknowledgments for the thorough relief which your skill has afforded me. S. R. C. Haverhill, N. H. Dear Doctor: After having been extricacted from a gulf, into which one has been plunged by his own youthful follies, and the excessive indulgence of his passions and appetites, it is not pleasant to recur to the misery and despair which you have alleviated in my case. But I should be wanting to myself, to you, and to society, if I was altogether silent after having been the sub- ject of your skill and care, until I have been relieved of the consequences of my follies. You have given me back the manhood which I had lost and forfeited. Why should I indulge in the gloomy details of my case with which you are so well acquainted, and which others reduced to a a like strait can readily imagine ? Suffice it to say that I am cured, and sit clothed and in my right mind. With the utmost esteem I subscribe myself, Yours ever, J. W. W. Boston, July 15, 1873. West Chelmsford, Feb. 25, 1873. Doctor Hayes: Dear Sir: — Yours of yesterday is at hand and with pleasure I would has- ten to reply. When I first visited you one year ago last January (1872), I 204 TESTIMONIALS. was a used-up man, both mentally and physically, and it was with much pain and suffering that I performed my daily labor, and my nervous system was in a very bad condition. It was with much difficulty that I could sit still and read a paper in the evening, and it was a common occurrence to lie awake in bed until eleven, twelve, one, and two o'clock in the morning, and then I would sometimes get up and stand on a stone doorstep, or go out into the snow barefooted and get chilled so that my nerves would get quieted down so that I could sleep. My head also troubled me very much. But now, by the blessing of God and your very skilful treatment, I feel like a new man. I can now sit and read without suffering from nervousness, and to use an old saying, "I can sleep like a pig." I often say to my wife that I never enjoyed sleep so well in all my life as at the present time. And in every respect I can truthfully say I am a hundred per cent better than I was one year ago, and a more healthy man than I was fifteen years age. I would most earnestly recommend you to all suffering from nervous disease as a true gentleman and a skilful physician. Most respectfully subscribed, A. W. Parkhurst. Commonwealth of Massachusetts. ) Middlesex, ss. $ Chelmsford, April 7, 1873. Personally appeared A. W. Parkhurst and made oath to the within state- ment. Before me, Jonas J. Hoyt,, Justice of the Peace. Foxboro', July 14, 1873. Dr. Hayes: Dear Sir: — Words will never express my gratitude to you for the help you have rendered. I feel as though I was a new man. I did not gain flesh while in the shop; have been out a week and gained four pounds, and am in most excellent spirits. I have medicine enough to last four davs, please send another supply on receipt of this. Yours truly, Fred N. B. TIONAL LIBRARY OF MEDICINE NLM DD5bD5E7 3 Mra NLM005605273