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REMARKS
.               ON THE
t
STONE  AND  GRAVEL
    KIDNEYS, LIVER AND BLADDER,

          WITH AN ACCOUNT OB" THB

      DISCOVERY OF A SOLVENT REMEDY,

    NOW USED WITH UNIVZK3AL SUCCESS, AND COMMONLY KNOWN A3

DR. LEE'S  GRAVEL  SPECIFIC,


        BY SAMUEL H. P. LEE, M.D.,
MEMBER OV THE MEDICAL, SOCIETY OF CONNECTICUT.
•a,7 ^'■•■-
'r*M For Directions, see Pages 12,13, and 14.
          NEW  YORK:
OFFICE,  No. 2 5, BIBLE  HOUSE,
ENTRANCE FROM A8T0R PLACE 
•
11  r
WJ
a
*W. 
1
.  Oopy of a letter from Rev. H.  Croswell, to his friend,  in answer to
      his inquiries relative to  Doctor Lee, and his practice in Calculus
      Diseases, as exemplified in h is own case.

                                   New Haven, Ct., December 15th, 1854.
  Dear Friend & Brother :
 f   I was  yesterday favored with yours of the 12th inst., and take plea-
 sure in giving  you a prompt reply,  knowing  how to sympathize  with
  your good friend  who is suffering from  complaints* probably,  similar
■t  to my own.
     It is  now a year or more  since I commenced the use of Dr. Lee'a
 "Specific  which  he calls the "Lithontriptic Pills,"  designed for  the
  cure of Stone and Gravel in the Kidneys, Liver, and Bladder.
     The result has shown that my case  was one of long standing, and
  that secretions were uncommonly numerous, and large.
     Doctor Lee claims that his medicine acts  as a solvent, and  such it
  has proved in my ca$e under its operation.   I have passed large quan-
_  tities of  calculi  in fragments, plainly showing that  they  are parts of
  stones too large to be  voided whole ; they are disintegrated  by the
  action of the medicine, but still retain  enough of the original shape to
  show that they are parts of larger  stones.   Of this  calculous matter,
  I have passed enough to fill a common wine glass, and  yet  some small
  particles continue to pass, so that I do not  yet call myself well, especially
  as these  passages cause me much painful irritation;   but during all this
  process,  my general health has been improving, and  I look  with entire
  confidence to a complete and permanent cure:  I am  satisfied there are
t  no new formations.
    And now as to the doctor himself, he  is a man of science, and has
  always been a Physician of high reputation : he is now devoting himself
 exclusively to this class of diseases,  and has obtained celebrity  in this
  way.
    A letter directed to Dr. Samuel H. P.  Lee,  New York, will receive
 his prompt attention.
    He will also send his pamphlet and directions, and  if your friend can
 lie persuaded to begin and persevere, I doubt  not that he will receive
 immediate benefit, and eventual cure, as I think his case will  hardly
 prove as  obstinate as mine.     Yours  truly,
                                                 H. CROSWELL.
Tlie following letter from Rev. H. Croswell, was addressed to Dr. S. H.
    P. Lee, 25 Bible House, Xcw York.

                                   Jfcw Haven, Ct., February 16th, 1858.
My Dear Doctor :
   As I ascribe under God, the continuance of- my good health to the
regular, though moderate use  of your medicine, I must beg you to
send another bottle, in the usual way, by express.
   You will feel yourself at liberty  to  cite my case  as one, in which
your remedies have proved eminently successful.
   It was, as you will recollect, an  obstinate case, and seemed  at  first
to present formidable obstacles  to a cure.   But those obstacles finally 
2
yielded—and after the steady use of your medicine, to the amount ol
over twenty bottles, and the discharge of at  least half a  pint of the
fragments of disintegrated calculi, I found complete relief.   I am now
79 years of age, but I am still able to discharge all my pastoral dutios,
with very little inconvenience.
            Very gratefully and respectfully yours,

Dr. S. H. P. Lkb.                          HARRY  CROSWELL.
Ext r art from a letter from Abraham  Baldwin, Esq., dated at Newailc,
    Xe'w Jersey, September 22d, 1S57, addressed to Dr. <<?. //. P. L.e,
    25 Bible Rouse, K  Y.

Dear Sat:
   I now address you, confessing along neglected duty in not sending
a statement of the wonderful cure you effected on nie, four years last
July.   It is not because I have forgotten to do my duty, for £  have
thought of you many times, and have mentioned your  name by way
of recommendation.   Soon after my  recovery, I  moved into t ae State
of Ohio.
     ********

   I now inform you  that I have returned to Newark, New  Jersey, to
spend the remnant of my days, which cannot be  many, as I am in my
80th year.  You will  be informed how I came to apply to you, in my
certificate, which you will find enclosed, and if I live, I will do'mvself
the pleasure of calling on you.  Respectfully yours,

To Doctor Lee.                         ABRAHAM BALDWIN.

   In the fojegoing was enclosed the following  certificate,  with a  re-
quest to publish the same.
   " To all to whom this may concern, I do hereby certify, that in the
month of July, 1853, I had for some time been afflicted with a stoppage
of my urine; we were engaged in getting in hay. I over-exerted my-
self, the weather being very hot, and in consequence was afflicted with
a discharge of blood  from  the  bladder with my urine.   I was soon so
reduced that I made my arrangements to leave the world: my brother's
wife, standing at the bedside said, "if he lives till morning,  I will send
for Dr. Lee of New York.   I should have  been in my grave six years
ago, if it had not been for Dr. Lee."  (She was affected with stones in
the gall bladder, and  had been relieved by Dr. Lee.) She accordingly
sent for Dr. Lee, who seeing my state asked my  age, she told him 76;
he thought my age against my chances for  a recovery, but after  ex-
amining  the blood which  I  had  passed, he said, he thought,  if  my
strength would hold out for a day or  two longer,  he might help me: he
gent me some powders, which stopped the bleeding, and also a  bottle
of gravel pills, which effected a perfect cure; I am now 80 years old, and
enjov good health.
                    ABRAJLAM BALDWIN, Newark, Now Jersey." 
TO   THE   PUBLIC.
  Some twenty-five years ago, I prepared a compound vegetable Sol-
vent for a patient most severely afflicted with the Gravel and Stone in
the kidneys and  bladder, which effectually  and speedily performed  a
radical  cure.  Such was  the  powerful operation of its solvent  and
cleansing properties upon the renal'organs,  giving ease and comfort in
the most distressing paroxysms, and finding the same  happy effects in
every case and in numerous other cases, I adopted it in my nomencla-
ture of practice, for all calculous affections of the kidneys, bladder and
gall ducts, with equal and satisfactory success.  From that period to the
present time, I am  very frequently called upon for this medicine from
all parts of the world where Yankee Enterprise  has  invited those once
cured, who communicated the facts to their suffering neighbors.
  This Medicine  is now before the public, based  on the fairest prospect
of doing much good to suffering humanity.  Its distinguished merits over
every Lithontriptic I have ever known, warrant and  sustain my  firm
belief in its future celebrity—a celebrity not dependent upon  puffing
advertisements, but on the smiles of happy mortals, proclaiming to the
world a sovereign  remedy.  No one,  of any age, sex, or constitution,
however severely afflicted, or however long, need to despair of a cure—
or at least manifest relief.  A  short trial will convince  the most skepti-
cal of its powerful  influence, and insure a perseverance until a  radical
cure is effected.
  To Medical Practitioners, and more particularly to those who have for
many years found my Bilious Pills  a convenient  and  effectual cathartic
in their daily practice,  I venture to presume upon their disinterested
philanthropy,  and invite  their attention to the trial  of my Solvent
Lithontriptic, and can assure  them that their success wi'l exceed their
highest expectations.

         Votes of the Connecticut Medical Society.
At a meeting of the Fellows of the Connecticut Medical Convention
                          October, 1794.
  Voted, That the thanks of  this  Society be given to Dr.  Samuel H.
P. Lee, JVeut London, for his  ingenious answer to their second prize
question, upon Autumnal Bilious Fevers.

  At a meeting of the Fellows, &c, in May, 1797,
  Resolved,  That the thanks  of this Society be given to Samuel H.
P. Lee, JVew London, for his  answer  to their prize question—" What
is  the best  method of preventing Qutnsy, (Cynanehe Tonsillaris of
Dr. Cullen) after the inflamatory state is fully formed, from  termi-
nating in maturation and discharge ?" 
4
  The following  notice  appeared in the  JVew   York  Express,  in
October, 1840 :-*-
  " Infirmary for the Gravel.—Doct. S. H. P. Lee, for so many years
known as the discoverer of the  celebrated New Loncron Bilious Pills,
has removed  to this city and opened an Infirmary at No. 36 John street.
Dr. Lee is so  well known  through this country it is hardly necessary to
speak of him.  We have been acquainted with him for thirty years.  He
is a regular physician of established reputation—a gentleman of intelli-
gence and character. For a number of years he has been a successful
practioner for that disease, which is said to be so excruciatingly painful
and dangerous.  He has established himself here to extend his sphere of
usefulness,  and has exhibited to us a great number  of private letters
from highly respectable persons, who state that  they have been  entirely
cured under his treatment.  Dr. Lee is a gentleman in whom the public
may place entire confidence."—JV. Y. Express.
                From the JVew Era. July 22, 184L
  Dr. S. H. P. Lee.—The Courier and Enquirer says that this gentle-
man " has discovered one of the most important remedies in the Materia
Medica [alluding to his  remedies for the gravel], and  from our own
knowledge of its sure efficacy in  curing a disease, than  which there is
scarcely a more painful or more dangerous one in the long list of which
frail nature is afflicted,  we do the public more  benefit than we  can
possibly do him in making known the Bource where the malady can be
removed.  Dr. Lee is well known throughout the country in his general
character of an able and learned physician of long standing ; but he is
not so well known as he should be for his eminent success in the particu-
lar disease to which he  now devotes his attention.  An educated man
like him, who has ranked with the highest of his profession in his own
State for  years, and who, with the nice feelings of a gentleman and a
Bcholar, disdains the clap-traps of quacking, is not very likely to seek a
newspaper notoriety; but knowing him as we do, we have the right, we
think, to say what we have of him."—Editor JVew Era.
From the Pennsylvania Enquirer and Daily Courier of October 22,
                  1841, Published in Philadelphia.
  " A highly respectable citizen called upon us yesterday, and stated
that he had received much benefit from the remedy described below—
also that he had heard of its efficacy in several other cases, and requested
us to give it a place in our columns, not in any puffing spirit, but for the
benefit of suffering humanity.  The medicine, we learn, can  only  be
obtained in New York.
  " The Stone and Gravel.—Whoever can arrest the progress of these
dire foes to human health and happiness, must be deemed an eminent
benefactor to his species.  We understand, from authentic sources, that
Doct. S. H. P. Lee, who is a regular practitioner  of medicine, and has
long been of high standing in his  profession, has  effected many remark-
able cures in these distressing complaints, and never fails to afford early
or immediate relief.  We, therefore, but discharge a duty to humanity
in giving publicity to these facts, and cannot but think that other paper*
by so doing would confer a benefit on the community." 
5
  In the American Journal of the Medical Sciences, for October, 1844,
is a communication by John 0. Warren, M.  D., Professor of Anatomy
and Operative Surgery in Harvard University, Boston, on Lithotrity, in
which the Doctor mentions the case  of a lady in Boston who was cured
with Dr. Lee's Lithontriptic Pills.  See p.  306, in a note, as follows,
viz :—
  " In the case of another  lady, a patient of mine, who employed Dr.
Lee's Lithontriptic Pills, the patient was  relieved soon after she began
to  take them—was ultimately cured, and I believe now continues well
at  the end of a year.  The calculi consisted, in the case of this lady, of a
great number of Lobular Stones, each about double the size of a pea,
and composed of white carbonate of lime.  This lady had employed the
alkaline carbonates before  mentioned, and also sulphuric acid, without
benefit."
Extract from a Pamphlet edited by Mr. Charles Holt, on the  Yellow
                Fever in JVew London, Connecticut.
                     OF THE PHYSICIANS.
  " As during the ravages of this  terrible disorder, medical assistance
was  the greatest concern of the  people, it  may  not be improper to
mention their accommodation in that respect.  Early in the sickness, all
the physicians (but one, who was too much indisposed  to practice, and
another, Dr. Rawson, who was violently attacked by the Fever), deserted
the city, excepting Dr. Saml, H. P. Lee, to whose lot it fell, alone and
unassisted, to combat the fury of this  dreadful pestilence, and his con-
duct on the occasion was such as  will call the warmest sentiment of
gratitude and  esteem  from the  citizens of New London, as long as the
remembrance of the Yellow Fever  shall exist in their minds.  He cheer-
fully sustained the arduous task of  visiting and supplying with medicine
from thirty to fifty patients daily, notwithstanding the great fatigue and
danger of infection to which he peculiarly exposed himself.  How many
owe  their safety to his skill and assiduity it is impossible to know,but
iu all probability there are now many  enjoying the invaluable blessings
of life  and health, who, but for his benevolent care, would have been
tenants of the house  of  rest.  In  discharging the important duties to
which he so nobly devoted himself, he was seized with the prevailing
disorder, but after a struggle of a few  days, was happily preserved from
falling a sacrifice to his humanity."

From  the  Brooklyn  Annual  Visiter, published  by  Dr.  Martin  K.
                      Bridges, D. D. S., 184a
  Dr. S. H. P. Leb's Infirmary for the Gravel. 36 John St. N. Y.—
In the last year's edition of the Dental Mirror, we gave a brief notice
of Dr. Lee's Infirmary, Ac., as above.   It was from the purest motives
of benevolence and sympathy for those afflicted with this painful disease,
and  a desire that such might profit from the information given  by us,
that we gave place to the article at all.  We gave the noti«e then, as
now, without solicitation from any source whatever, and we take this
opportunity to repeat what we said  last year, viz :—Dr. Lee does not
need our  puffs or praise, and this  is not the object of this communica-
tion ; but it is to give information  that will lead to the speedy recovery 
6
of those afflioted with one of the most alarmingly painful diseases thai
human nature is subject to.  We speak from actual knowledge, having
used the medicine effectively in our own case.  But cases of a much
more  alarming character (where a perfect cure has been performed by
Dr. Lee's medicine), have come under our knowledge, and we unhesita
tingly give it as our opinion, that Dr. Lee's Lithontriptic, by the bless-
ing of Providence, will conquer the most obdurate case of Gravel that
can be found in our country.  We refer our readers to Miss Anna Mapes,
of New York, who was brought to the very brink of death in the mosl
emaciated state ;  after being  given up by everybody, she was miracu-
lously, as it were,  cured by Dr. Lee's Medicine in a few weeks.
                                              Martin K. Bridges.
  Brooklyn, Jan. 80/*, 1343.

                         --------«*--------
A few Observations on the History  and Progress of  tha
                            Disease.
  Ever since the days of Hippocrates, medical men have been anxiously
looking for a solvent  for the  Gravel and Stone in the kidneys  and
bladder.  The ancients  investigated  the subject with great ardor—tried
m^ny experiments with such articles as were known to dissolve calculi
out of the body; but failing to reach such substance through the sangui-
ferous system, gave up the pursuit, and rested their  hopes upon the
future developments of medical science, fully  persuaded  that so formi
dable a disease must have an antagonistic remedy, with specific power*
to dislodge the system of such extraneous  particles.
  The Greek Physicians made some  progress in preventing, but none in
curing the disease.  They very properly conceived the idea, that a viti-
ated and deranged  digestion laid the  foundation for impurities in the
blood, which, in passing through the  emulgent  secretions, formed  a
viscid mucus, combining with the uric or ammoniated salts (as they con-
ceived), thereby generating earthy substances, and lodging in  the kid-
neys, and from their irritating surfaces forcing  their passage  through
the ureters into the bladder, there to accumulate into stone,  or, per-*
chance pass off by urine. During the early ages of Christianity, medical
men did not relax in their researches, but laid the foundation of a mora
rational system of Pathology, by the adoption of  articles taken into tha
stomach, having a direct action on the kidneys and emulgent secretory
organs.   Galen,,Paracelsus,  Helment  and others, up to  the time  of
Booerhave, exercised all their physiological powers  to  this object;  bul
their success was evanescent and unsatisfactory, and seemed to yield to
the induction of operative surgery,  among the improvements of which
Lithotomy  took the foremost rank  as a substitute  for Lithontriptics.
From the days of Booerhave to the present time, the science of medicine
has  undergone great and important changes, by the revolutions pro-
duced from chemical developments, and raised the  expectations of
many, that as the ancient doctrines  of earth, air, and water, long sup-
posed to be primary elements, has become merged in the discovery of
their heterogeneous combination, a  prejudice in favor  of chemical
remedies was introduced, which, by dissolving  calculous  concretions 
1
 sut  of  the  body, were  confidently expected to pass the barriers  of
 digestion, instead of entering the circulation  and the secretory vessels
 of the kidneys unchanged.  The Pathology of the disease, and  the phe-
 nomena of urinary calculi, examined by the new chemical tests, opened
 the flood-gates of genius, and the most  fanciful theories, founded on the
 doctrines of acids  and  alkalies,  prevailed.   Each administered those
 agents  beyond the compatibility of direct medicinal  influence, and so
 brought their practice into disrepute.  Most of their medicines being of
 a caustic and irritating nature, the delicate and sensitive membranes of
 the bladder suffered nearly as much from the morbid infiamation they
 produced, as from the mechanical action of the sharp points of gravel.
 Still the experiments went on, and the hopes and wishes  of the most
 zealous confidently expected  that some by lucky hit or accident (as most
 of the useful  discoveries in combined medication are obtained), a  sol-
 vent detergent adapted to the case would be produced, which genius
 and  chemical philosophy had failed to accomplish.
  An eminent French writer (Paris) says " The urine may be consid-
 ered as one of the most heterogeneous of animal fluids ;" and  this
 remark is verified by the fact, that from the elaborate  analysis of Berze-
 lius, he found this fluid holding in solution thirteen different substances.
 Hence the impracticability that a single agent could dissolve those extra-
 neous substances in the body.  Combinations, multiform  and antago-
 nistical in their vital  action,  were resorted to with no better  success;
 and  palliative remedies, with the quieting  powers of opium, were the
 only leading indications of the schools  of medicine for the last century
 in this disease.
  These remarks lead  me to announce to those suffering under this
 malady, that I have made a Pharmaceutical discovery, in the combina-
 tion of vegetable and chemical agents, which, when administered, dis-
 solves calculous concretions, and ejects them from the kidneys and blad-
 der in the urine, and also from the gall bladder and liver ducts.
  This  important and long-looked-for desideratum is now fully demon-
 strated, by a course of practice for many years unexampled  in  its suc-
 cess.  Among the numerous cases which  have been cured by this remedy,
 a number of the  certificates have been drawn up by the sufferers them-
 selves, and voluntarily communicated  for the benefit of the afflicted,
 supported by facts which cannot be controverted.
  Medical men may possibly doubt  the existence of  such  a  discovery,
and  exhaust  their argumentative  powers, under the banners of modern
chemistry, and arrive  at conclusions  apparently satisfactory.  But it is
ever to  be remembered, that theory  is one thing, and facts resulting
 from well-tried experience, another.   I  trnst  that no one who claims to
sympathize with his suffering patients, will yield to professional preju-
dices until he has tested the  powers of  my compound.  The  success of
this remedy authorizes and requires my exclusive attention to this dis-
ease.  The afflicted at a distance may consult me by letter (postage paid),
describing their cases from the commencement, giving  the leading symp-
toms which characterize the disease, the remedies used, state of  the consti-
tution  and condition of general  health, Sec., and immediate attention
will be given to all  such applications, if accompanied with  a fee of five
dollars, which will procure one bottle,  which will last thirty  days ; bul
if ten dollars be remitted, three bottles  will be sent. 
8
  Physiology and Patliolopy of the Kidneys and Urinary
                           Organs
  The subject of Calculous Diseases is one of the highest importance,
not only on account of the number and variety of the phenomena which
it embraces, but also on account of the pain and deep anxiety which the
patient suffers.  In the wide field  embraced under the term of Urinary
Diseases,  most striking aud important improvements have been/rf late
effected.   The recent discoveries in Animal  Chemistry, together with
the application of the science of  Histology, have  added largely to our
knowledge, both of the Physiology and Pathology of the Kidneys ; and
every step in advance has made the necessity  of studying the qualities
of the urine in almost every one of the diseases with which the  body is
afflicted, of paramount importance in forming  a correct diagnosis.
  The due discharge of the functions of the kidneys, is  essential to the
general well-being of the frame.  The slightest inefficiency in this respect
is felt injuriously somewhere, while serious lesion is fatal; and so on the
other hand, changes in the health  generally disturb, in a similar manner,
the functions of those organs which secrete and excrete the urine.  The
kidneys, then, maybe considered the barometers of health, and the urine
representing the quicksilver, requiring only a chemical and microscopic
eye for the detection of its degrees and kinds of  Pathological changes.
Professor Houston has very justly observed that the examples of derange-
ment of the kidney producing general derangement of health are numer-
ous,  and in all such it is chiefly by an examination of the urine that the
nature of  the lesion is to be ascertained.  Persons have  been long and
lingeringly ill; they have dropsies, shiverings, and convulsions, or even
madness, and sometimes all these affections together, and they have died;
nevertheless, neither during life-time, nor after  death, was the true nature
of their malady known,—they have  been reported as having  died  of
Liver Complaint, of  Cerebral Affections, or simply of Dropsy;  and no
doubt they were treated with a view to the cure of such supposed affec-
tions.  Many, in all ages, have lingered along and pined away thus, and
yet it is only within a few years past that a satisfactory solution of the
cause has been discovered.
  The profession are indebted to the perseverance and genius of Doctor
Bright, of England, for having traced  these  protracted conditions  of
illness, and those melancholy deaths, to their  true source, viz.:  a slow.
insidious,  and often  unappreciable degeneration  of the kidneys.  This
disease, although in itself but little striking, and therefore so loug passed
over unobserved, is nevertheless sufficiently decided to spoil the secretion
of the kidneys, and send one of its most poisonous excretions, the Urea,
which should be discharged with the urine,  back through the frame, poi-
soning the springs of life at their source, and thereby agitating and
paralyzing all the vital functions.  The Pathological condition of the
kidney characterizing such cases is  now well established, and the evi-
dence  during life of its presence, and the test of its existence at that
period while it is still curable, is a chemical one, viz.: Precipitation of
Albumen from the Urine.
  There are various deposits  or sediment found in the urine, the results
and the evidences of certain corresponding diseases, aud the exact nature
of which can easily be detected  by the microscope, often  a  matter of
importance in forming a direct diagnosis. 
9
  The urine in its natural state is composed of a number of ingredients,
(viz.),  Urea. Uric or Lithic Acid, Lithate of Ammonia,  Sulphate of
Soda,  Sulphate of Ammonia, Phosphate of Soda, Lime, Magnesia,
Animal Matter, Sfc, which are held in solution, so long as  they preserve
the natural temperature of the body; sometimes, however, it happens
that one or  more of  these  ingredients is  deposited in  a solid  form.
although the urine has undergone no change in its temperature, and even
while it remains in the bladder or some other of the urinary passages.
These deposits are sometimes in the form of small particles, or in larger
masses, the latter are called Calculi.  The urine contains  a large quan-
tity of Uric  or Lithic  Acid, whenever there is a superabundance  which
precipitates the Lithic Acid Sand, the  urine is bright and transparent
to the eye,  of a bright copperish color, resembling in appearance Madeira
wine.  In general, the patient is troubled with dyspepsia, and, sometimes,
the gout.   Many circumstances, says  Sir Benjamin Brodie, demonstrate
a close connection between this latter disease, the gout, and the forma-
tion of red sand in the urine.  The same peculiar state of the system
which  makes you subject to the one, also makes you subject to the other.
The red sand  is composed of fine pure Lithic Acid, whilst the chalk
Htones in gouty subjects are composed of the same  acid in combination
with Soda, and the sediment in the urine of gouty subjects  is the Lithate
of  Ammonia.   It is  the Lithate of Ammonia also which  forms  the
principal part of the sediment, deposited from the urine, in the chamber
vessel of persons laboring under dyspepsia, and some other bodily ailments,  j

                History of ILithic Acid Calculi.
   The prevailing opinion with respect to the formation of Lithic Acid
Calculi, is  that certain kinds of food, and particular constitutional pre-
disposition, and  atmospheric  influences  are supposed to generate a
Lithic Diathesis ; that state of the system, characterized by a tendency
to an increased secretion of Lithic Aoid from the Kidneys.  This Acid
and its Salts are apt to concrete in the Kidneys, or ureter, forming
Gravel or  larger masses, which by and by make their  escape into the
Bladder, forced  down  by the Urine,  (tearing and abrading  sometimes
the blood vessels,) and producing fits of Nephritic pain or Colic; some-
times  these small Calculi are retained in the Bladder, receiving a depo-
sition of fresh calculus matter from the urine, increasing in size, pro-
ducing much annoyance, inflammation, and pain in the Bladder, Urethra,
and Glans Penis, impairing the general health, and producing a Cha-
chectie state of the system, and a new Diathesis called  the Phosphatic,
in which there is an increased secretion  of Phosphates, which  deposit on
the nucleus already formed by the lithates.
   Some  medical writers hold  that the  Kidneys are mere machines to
separate from the blood those substances which are unfit for circulation,
and that when they become functionally disorganized, a train of second
tiry diseases sapervenes with morbid changes in the quality of the Urine,
and, if allowed to take their natural course, often terminate  in the  des-
 truction of the Bufferers; others again, rank them  as secretory organs.
 having a duty to perform of equal importance to that of the lungs.
 * The" mine, in a healthy  state, is a light amber color, in a morbid or
 ii«. ised state, it partakes of every shade and color—Red, Brown, Pink,
 and White—depositing a red brick dust or ash sediments,  and sometimes
                                   1* 
10
white as sea sand.  The Lithic Acid  in a poisonous element, amongst
this family of rebellious phosphates, and foremost  in the war of disor-
ganization of the kidneys aud kindred organs.  The functions of the
kidneys are impaired, and a train of secondary affections constitutes the
catalogue of diseases called Gravel and Stone, the miseries of which are
indescribable, and unless arrested in their career of mischief, end  in a
painful and desponding life of distress, until death closes the scene.
 Symptoms of Disorganization of Kidneys  from a Lithic
                         Acid Diathesis.
   The gravel in the kidneys and bladder is attended with a fixed pain in
the loins, numbness of the thighs, nausea, vomiting, and not unfrequently
with a slight suppression of urine.  As the gravel removes from the kid-
neys down into the ureters and bladder, it sometimes produces such acute
pains as to cause faintings and convulsions.  The patient, at times, can-
not bear any kind of rough motion, or great exercise, without enduring
great torture, a discharge of bloody urine, and some degree of temporary
suppression—pain in the neck of the bladder, tenesmus,  or griping and
itching of the Spincter Ani—cold chills, uneasy desponding feelings,
inaction and lassitude of the whole body, discharges  of bloody urine,
depositing a sediment of gravelly matter, sometimes red, at others of an
ash oolor, with a glairy mucus, covered with filaments  or stringy sub-
stances.
   These symptoms are  generally  aggravated by exercise, particularly
 j wding on horseback ; and from  a long continuance of pain, and from
that want of re3t which frequent returns of the  paroxysms are sure to
induce, the patient's state of health by degress becomes much impaired,
and unless some effectual means are now employed for removing the
cause, it commonly happens that his misery is only terminated by death,
or a life spent in misery and distress.
  In addition  to these symptoms, there is often a dull heavy uneasiness
in the small of the back and loins,  referable  to the neck of the bladder,
with frequent desire  to urinate, with  a small  stream, droppings and
total  suppressions.  Sometimes  the  stream passes in  a spiral form,
attended with great heat and anguish. The bowels are strongly inclined
to costiveness and  dyspepsia, muscular debility, emaciation,  loss of
appetite, palpitation  and  hypertrophy of the heart, swelled feet,
anasarca, dropsy, are often concomitant symptoms.

     Symptoms of Stone in the Kidneys and Bladder.
  The celebrated Doctors Prout, Wallaston, Brande, Marcet, Willis, Ma-
gendie, Telloly, Chrisiston, &c., &c, describe the formation of lithic acid
calculus in the kidneys as without any  premonitory symptoms of suffi-
cient consequence  to attract the  patient's notice.  Not unfrequently,
indeed, the patient does not suspect  that he labors under any kind of
disease, until he finds a small calculus expelled with  the urine.   At
other  times, however, the presence of a calculus in the kidney is indi-
cated by a pain in the corresponding  loin, extending from thence down-
wards towards the groin  and testicle, accompanied with a  sense of weight
in the loins, and occasionally with tenderness.  After exercise, the urine
is tinged with blood, sick stomach  and vomiting.  But all these symp-
toms are subject to great variation.  Sometimes  the pains are trifling 
11
at other  times very severe ;  or there may be much pain one  day, and
little or no pain at all another.   There is, howevet, more pain where the
calculus  is associated with a disorganized or diseased kidney than when?
the kidney is otherwise healthy.  Patients with enlarged prostate gland
are particularly liable to suffer from calculi in the bladder.   The tumoi
prevents the bladder being emptied without the aid of the catheter. Foi
the same reason, lithic acid sand, particles of phosphate of lime, or any
thing else which can form a nucleus, becomes the foundation of a stone
in the bludder.
  The Pathegnomonic  symptoms  of stone  in the bladder  are  so well
defined by Sir Benjamin Brodie  in his excellent  treaties  on urinarj
diseases  from lithic acid, that I refer  to it, with a single remark, how-
ever, that 1 have known many cases where these symptoms were illusive
—for on  sounding, no stone was found ; but such doubts can always  bo
solved by sounding.
  Again, there have been instances where very eminent surgeons hava
resorted  to the knife, under  these delusive signs, and found nothing bul
lithic acid sand  and the  phosphates, intermingled  with  mucus and
animal matter.
  That stone  in the bladder may be disintegrated  and dissolved in  iti
seat, by the use of Lithontriptics, through the secretory system, and  bj
injections through the urethra, is proved by such eminent authorities a»
Fourcroy and Vaquelin, in France; Berzelius, in Sweden; Willis and
Sir Benjamin Brodie, in  England ;  M. M. Bobiquet and Charles Petit,  of
Paris ; who have,  in different ways, performed the feat.
  The discovery of the alkaline properties of the Vichy waters of Lom-
bardy, has also furnished cases in  point, as verified in the case of M.  de
Longperier, in 1836, by  Doctor Petit, reported in that excellent work  on
urinary and calculous diseases,  by Robert  Willis,  M. D., of the Royal
College of Physicians, London.  See pages 177  to  181, Phila. edition,
1839.
  In the course of my  lithontriptic practice, during  the  last  twenty
years, cases of disintegration have frequently occurred,  manifested  by
copious discharges of fragmentary  and globular stones, from the size  of
a bean to a small  mustard seed, sometimes in very large quantities, and
whenever a previous sounding has been made, I have found a stone  aa
large as a waluut.  Such cases require a long and  steady perseverance
in the use of my solvent; not only months, but in cases where the stone
is composed of laminae combining  the  phosphates of lime and ammonia
with a lithic acid  nucleus, more than a  year is requisite to its disintegra-
tion.  In such instances, the reader should be aware of the importance
of unimpaired constitutional energies, and  sound organs, or otherwise
the patient might sink under the influence of secondary diseases, such as
dropsy, morbid affections of the  liver,  and other organs, associated with
symptoms of general constitutional disturbance, while, at the same time,
the stone  is  under the progress of disintegration, and  passing off in
lithiates  and granular particles.
  There  are various other modes of removing stone from  the bladder
Buch as  Lithotomy, or cutting—Lithotrity, or crushing  with  instru-
ments—or by  injecting a menstrua to  act directly on the surface of the
stone, in the bladder.
   It would be supererogatory in  me   to hazard my opinions  on ♦*= -- 
12
three modes of removing Vesical Calculi, when impacted in the bladder,
as such results are familiar to every medical man who reads the medical
literature of  the  day.   But I will venture  to assert that in many cases
of stone in the bladder, my Lithontriptic will, through the secretory sys-
tem, disintegrate  and dissolve into fragments and granular form, stones
of various size, more especially where the censtitutional powers are not
retrograde, or in  a sinking condition also.   I assert, that after the ope-
ration of Lithotomy or Lithotrity (for neither removes the remote
cause, to wit: the  Lithic Acid in the  blood),  my solvent prevents a
recurrence of  the disease, when taken daily for several months.
  In the course of twenty years past, I have had many, or rather several
who had passed through the  ordeal of both Lithotomy and Lithotrity,
when the disease had returned upon them, and instead of repeating those
operations, have relied on my Solvent with success.  Mr. Charles Mas-
sey, Jr.. of Philadelphia, was a case in  point—aged 60—had  a stone in
his bladder—was operated upon by crushing, with only  partial success—
suffered much from painful paroxysms at the neck of the bladder—com-
menced  a  course of my Lithontriptic, and in less  than two years
perfectly recovered, and passed the nucleus as large as a large bean—
since then is well and enjoying the best of health.  I am permitted to
refer any gentleman to him for  further particulars, who may request it.
  This medicine is also recommended in a variety of other complaints,
viz.: Sour Stomach, Gout. Rheumatism  of the Joints, Dyspepsia, Leuo-
chorrhea, or ( Whites in Females), Dropsy, Vomitings, Diseases of the
Heart, Liver, and general infirmity of Constitution,  which are secoudary
to granular degeneration of the Kidneys, also in infantile diseases, such
as painful micturition of Urine, Suppressions, &c.—Diabetes and diseases
of the Prostate Gland.
  Children under 10 years of age, should  take  half the quantity,  or
half sized pill  in same divisions of time.
Directions  for Using- Or. S.  H. 1*. Le>N lithontriptic Pills.
  Take a pill of the size of the sample pill in the bottle (ten or twelve
grains each), in the morning, on an  empty  stomach;  another before
dinner ; and another at bed-time;  washing it  down with  water or
tea.
  If the bowels are costive, first open them with any familiar purgative,
or with a dose of my genuine Bilious  Pills.   (If genuine, the envelope
direction paper will be signed at foot, with pen and ink, my proper sig-
nature, similar to the same  on each bottle of the Lithontriptic).
  A daily diet drink of Dandelion tea, made of the roots of the present
year's growth, as prepared  by the Shakers, about  the strength of  black
tee, as usually made ; which may be drank  at pleasure, equal to a pint
or more in twenty-four hours.
  The patient's diet may be continued as usual,  with the exception of
pickles, vinegar, cider,  sour wines,  lemonade, sour  apples,  &c.  But
cooked apples, cranberries, and sub-acid fruits may be eaten moderately,
r>ne or two hours after taking a pill.
  Honey may be used at pleasure.  Sugar and milk may be used in the
Daudelion tea. if liked.
  The Lithontriptic Pills should be continued as long as any symptoms
of the complaint are perceived ; it will not interfere with any out-door 
13
exposure, travelling, if able, or gentle exercise in suitable weather.  It
may be continued for months or years, according to the obstinacy of
kidney complaints,  or other organic affections, improving, the general
constitution at the same time.
  He should observe the same rules of diet and exercise that a temper-
ate habit would enjoin upon a healthy person.  Persons engaged in any
active employment on land or water, may use the medicine without any
ill effects.  Its salutary results are  soon  perceived by a passive amelio-
ration of all the  distressing symptoms, and a freedom of the secretory
evacuations; and it should be persevered in until the complaint entirely
disappears, and the urine has a natural  and healthy appearance.  To
dissolve the calculi or gall stones in the biliary ducts, known to exist by
the violent paroxysms of sharp, cutting, pungent pains at the pit of the
stomach, extending through the region  of the liver,  and vomitings,
accompanied with white or light-colored  stools, the medicine should be
continued two  to eight  months.  To prevent a recurrence of  the  gall-
stones, the Solvent should be continued, about two pills per day, for one
or two years in bad cases.
  But when the disease  is of long standing, or a large stone in the blad-
der or kidneys is  to be dissolved, it will take from five to twelve months.
The dose may be  increased in such case to equal four and even six pills
in 21 hours.  To make the cure permanent, and to restore the fraids and
secretory organs  to a healthy sound state, it would be advisable to con-
tinue the medicine, reduced in quantity to a pill per day, for weeks, or
months, according to the previous  violence of the disease.  This medi-
cine is also good in a variety of other complaints,  as sour stomach, gout,
rheumatism of  the  joints, dyspepsia, infantile diseases, such as cholera
infantum, heat  and excoriation of urine, strictures in the urinary passa-
ges, <fcc., &c.   Children  under ten years of age,  Bhould take  half the
quantity, or half sized pills, in the same divisions of time.
Rules to be observed while taking- Dr. lice's TIcdicine for
                     the Gravel and Stone.
  1st.  All other medicine of an alterative character, of any description
whatever, commonly used or recommended for the disease is strictly pro-
hibited ;  this prohibition however, is not meant to  include Anti-spasmo-
dics, or Cathartics, if from the violence of pain, or nervous  irritability,
or constipation of the bowels, remedies to remove either, such as Opium,
Morphine, or any customary active Cathartics to  open the  bowels, are
indicated.  AVhen purgatives are necessary, the gravel medicine should
be omitted during the operation, and resumed as soon as the bowels are
opened.
  2d. All Acids, such  as  Vinegar, Pickles, Cider,  sour Wines, sour
Dread, sour Fruits, Lemon Juice, sour Oranges, Apples, Lemonade, &c,
are to  be strictly avoided, as they will change the character of the medi«
cine in the stomach, and render its effect inoperative.
  3d. The  patient's diet and regimen may  be continued  as  usual, with
the exceptions of  acids as above.  If accustomed to Gin, Brandy, Ma-
deira,  Sherry,  or Port Wines, they may be continued moderately, if de-
sired.  All kinds of  food that  is  easy of digestion, either  animal  or
vegetable,  should  be   preferred.   Moderate  exercise  aud  atmosphcrio 
14
exposure, as usual, does not interfere with the action of the Solvent in
the system.
  4th.  The medicine should be taken from half an hour to an hour pre-
vious to eating any food.
  5th.  A patient perseverance in the use of the medicine, as long as any
symptoms of the disease exist, is recommended, the use of which is  al-
ways sure to improve tbe general health, appetite and digestion.
  6tb.  Honey may bo used freely in the tea, if desired.
  0&~ In all cases, I earnestly recommend cutaneous friction over the
whole surface of the body and limbs, with as stiff a brush or crash towel
as the delicate skin will bear wtihout laceration.   A hair brush is best,
used twice  a  day.  There is an  important sympathy between the sur-
face and internal organs, by  which a healthy action is given  to  the
whole secretory system.  It is a luxury even to the healthy, and will pre-
vent many secondary diseases in the kidney complaints.
                         Testimonials.

  The following certificates, among a great number of the same tenor,
were sent to me by the writers, with a desire that they  may  be  made
public for the benefit of mankind :
                                          New York, October 24,1829.
  It is with great pleasure, and a duty I owe to  the public welfare, that
I hereby acknowledge the great utility of Dr. S. H. P. Lee's celebrated
Pills, for the cure of the Stone and Gravel in the kidneys and bladder.
I have used them for some length of time in my practice, and am happy
to say have uniformly found them successful.  I may  also add the testi-
mony of many of our first Physicians  in this city, who have used them
in numerous instances, aud speak of them in (he highest terms.
  With  these facts to support their beneficial effects, I do with the ut-
most confidence recommend  them  to all those who  are afflicted with
these distressing complaints.    (Signed)          T. Jones, M.  D.
                                       New York City, October 20, 1929.
  I am fully satisfied from much experience in my practice, that Dr. S.
H. P. Lee's compound Pills for the Gravel and Stone, with  their conco-
mitant Nephritic  symptoms, are an invaluable medicine, and  infallible
in almost every case, by eradicating the Stone or Gravel from  the blad-
der, and so correcting the blood as to remove  the tendency of the kid-
neys and renal secretions to deposit calculi in the bladder—the cause of
Stone ; thereby avoiding  the severe operation of Lithotomy, or cutting
into the bladder.  I have used the medicine freely, and it has invariably
removed the complaints, affording ease and comfort to the patient.  The
article is worthy the attention of the public, particularly those who labor
under those distressing complaints, and in my opinion, is the nearest to
a perfect remedy  of any composition to be found in any Materia Medica
or medical writer.                     Jasper  C.  Foster, Surgeon.
  The writers of the following are grave, honest men, of the first stand-
ing for moral and religious integrity ; their object ?s the welfare of the
afflicted.   Those living in 1839 have informed me  they are entirely free
from the complaint. 
15
                                        Waterford, Conn., June 5,1S80.
  To whom it may concern.  This is to certify, that I have been troubled
with that distressing complaint, the Gravel, for twelve years—have had
many poor turns, so  that I  had to lay by all business   I was often
attacked with sharp, cutting, grinding pains  in  the kidneys, back  and
thighs, which are indescribable—after some hours, would seem to abate
for a time and then return, discharging thick bloody urine, with reddish
sediment, &c.  I had almost despaired of getting cured, especially when
I had the most excruciating pains imaginable—I tried  the Harlem Oil,
and  many other  remedies.   I  consulted physicians,  some  of  whom
informed  me there was no cure for it—I  took their medicines to no
effect.  At last I heard of a composition of Dr. S. II. P. Lee, of New
London,  formed  for this disease, which  I took for  three or four weeks,
and at the same time drank freely of dandelion tea as a common drink;
as it was inconvenient to get the tea at all times, I carried the dandelion
in my pocket and chewed it.   I got  entirely well of the gravel in a few
months—taking the compound, the parts healed, and I have no return ot
it since.   I therefore certify this for the benefit of others afflicted with
the same complaint.                               Oliver Maxson.
  Oct. 1839.   Mr. Maxson still enjoys perfect  health,  and  m?j be
inquired  of at his farm at Waterford.
                                      Waterford, Conn., April 80,1829.
  This may certify, that I was troubled with  the Gravel upwards  of
seven years, for which time I was unable to do much business, and had
not much hopes of ever being able to do any more.  I applied to several
physicians in New York, Baltimore, and many other places, of the first
standing for medical skill, but received  no benefit from their prescrip-
tions.  I happened,  by  chance, to  call on Dr. S.  H.  P.  Lee, of New
London,  Connecticut, and after taking his  Pills, prepared for that
disease, three weeks, by  taking three pills a day, viz : one pill morning,
noon and night, I was entirely cured of  that grievous complaint, and I
have not been troubled with it  since.   This was  about ten years ago,
and I have known a number of persons who have  informed me that the
Pills have cured them.   Having some of the medicine  left. I  gave the
same  to  a Mr. Chaplin, of Lebanon, Conn., who  informed me  that it
cured him and his'wife also, and, that if requested, he  would  certify to
the same for the public good.                      Isaac Rodgers.
  The  writer of  the above informed me,  in  1843, that  he  remained
entirely well.  He may be inquired of at 160 Duane street, New York.
                                          Waterford, Ct., Feb. 8, 1881.
Doctor S. H. P. Lee :
  Sir—About three years ago my son, Wm. R. Beebe, came to my house
from the State of Ohio.  He  informed me that he had been  troubled
with the  Gravel for many years, and had employed all  the  doctors in
that part of the country, but  could obtain  no relief, and said he could
not labor.  He came on to see his relatives once more, not expecting to
live long in that situation.  He took your Gravel Medicine for about
two weeks ; it brought away a large stone and  much gravel from him,
und  on continuing the medicine he passed another ; he  got entirely
well and returned home. I have received  letters from him  frequently 
16
lince •  he informs me that he has not been troubled with the complaint
since.'  I found that I was troubled with that complaint lately, without
knowing what was the matter with me.  I took your medicine about the
same  time  he did,  and  it  cured me entirely.  I  can  safely  recom-
mend them  to others, hoping that  this valuable  medicine  may  have a
general circulation for the good of mankind.
                                 I remain your friend,
                                                    Paul Bebee.
                                     Waterford, Conn. \%ih Oct., 1839.
  I hereby certify that I have for a short time made use of Doct. S. H.
P. Lee's Pills, prepared for the cure of the Gravel, and have obtained
help  by the use of the same, having been troubled with the complaint
for fifty years.  I am now eighty-eight years old.  Jeremiah Brown.
                                      Waterford, Conn., July 10, 1829.
  This may certify that I  have been  troubled with the Gravel from
infancy, and by taking some of Dr. Lee's Pills, prepared  for  that pur-
pose, have got well.                                Polly Dunbar.

  The  following Letters are published  by  the special request of the
writers:—
                              East Haddam, Conn., January 28d, 1840.
Doctor S. H. P. Lee :
  Dear Sir—For several years past I have  been  subject to frequent
attacks of the Gravel in the kidneys and bladder, so severe at times as
to confine me to my house and bed, and my general health has  been very
much impaired thereby.  The attacks would come on with a severe pain
in the small of my back, across my loins, with numbness in  my lower
limbs, accompanied with cold chills, and great irritability of the stomach
and in the neck of the bladder, with a constant inclination to void urine,
attended with great disability  to do so, and  which deposited a red
gravelly  sediment,  &c.  Having taken the prescriptions  given me by
different  physicians, and deriving only temporary relief,  I  began to
despair of ever getting entirely cured, until recently ;  having a severe
attack last summer, I applied to your son at Leesville to prescribe some-
thing to relieve me.  He informed  me, that when he was in practice, he
had  entirely removed this complaint  in several instances, with your
compound Gravel Specific.   He obtained some from you for me, and  I
continued to take it according to your directions, for three or four weeks
when all my distressing symptoms were entirely  removed,  and  my
general health began immediately  to improve, and it is now, sir, more
than six months, and I have had no return of the disease, and my health
generally has been better this winter than I have known it for several
years, which I impute entirely to the effects of your medicine.   Having
recently  read youT Treatise on the  Gravel, it gave me great pleasure to
find that you had taken a course by which the public  are to have  the
benefit of your medicine, and as I hare had an opportunity of testing its
curative  effects in  my own  case, I shall most cheerfully  recommend it to
ail those who are troubled with  this afflicting disease.
                   I am yours &t..                  Hyram Chase. 
17
                                      New London, February >8, 1840.
Doctor Lee :
  Sir—I have been afflicted with  the gravel from my infancy ; when a
child, I can remember having often had a flat iron applied to my back,
and other remedies for pains; at seventeen years of age, I was severely
troubled with sharp pains in the kidneys and across my back and down
my thighs, with great heat and numbness; I discharged great quantities
of a reddish gravel and bloody urine, attended with great pain and heat
at the neck of the bladder; my kidneys became  swelled, dropsical sym-
toms threatened me, my general health became bad, I had frequent sup-
pressions of urine, and was obliged to resort to the catheter, &c., and thus
afflicted, and by turns so severely as to be obliged  to take my bed, with
Bickness at my stomach and in great agony all  over,  I passed about 20
years of my life (with the exception of short intervals), without knowing
what it was to enjoy a whole day in health ; I had in the meantime taken
remedies from our physicians,  with only temporary  relief;  I went to
New York and Philadelphia, and consulted the best Doctor and Sur-
geons in those places; I was operated on for stone in the bladder by Dr.
Wistar, President of the  Medical College in Philadelphia, but he found
only gravel and I dragged on a miserable life,  overseeing my business
as well as I could, in great pain and distress, concluding there was no
cure for me, until last summer, when Capl. Oliver Maxson, of Waterford,
recommended  your Specific, which he said had entirely cured him.  I
took your Solvent according to directions, drinking daily the dandelion
tea, and in a short time began to perceive the effects on my kidneys and
bladder,  different from any remedy I ever took before.  My complaints
gave  way gradually.  I discharged large quantities of  sandy  gravel,
mucus, and muddy urine; my kidneys are now restored to a sound state,
the gravel has disappeared, and all my distressing  symptoms gone,
except an occasional stricture of the prostate gland,  by taking cold or
heavy strain ;  my general health was never so good as now ;  my nerves
are restored to natural firmness, and I can enjoy my nightly repose with
quiet and comfort; and as I impute entirely my present  good state of
health to the power of your medicine, I send you this statement of my
case, authorizing its publication for the benefit of the  afflicted.
         I am, sir, yours respectfully,               Jonathan Sizer.
                                New London, Conn., February 28, 1S41.
Doctor S.  H. P. Lee :
  Sir—I should feel myself ungrateful to you, and  guilty of a much
greater injury to mankind, if I were to withhold from the public the
extraordinary cure performed by your gravel Specific in my own case.
  I had been afflicted for four years with that tormenting disease, the
Gravel in the kidneys and  bladder attended with  sharp  grinding pains
across my loins, running to the neck of the bladder ;  at  times irregular
discharges of discolored and bloody urine—sometimes white and milky,
at others dark and  muddy; at  times totally suppressed, and when  dis-
charged would carry with  it large quantities of a reddish sediment of
particles of stone, accompanied  with  sickness at the stomach, vomiting,
chills, occasional fever, a sense of numbness down  my lower limbs^jvith
nervous irritation over the whole system.
  This train of symptoms so destroyed my constitution that I was obliged 
18
to give up my mercantile business, and seek relief as  I  best  could
While in this situation, and getting only temporary relief from my kind
physicians, I was told  of your medicine; but having little faith  in the
power of any medicine as an efficient remedy, I hesitated about  trying
it;  but the persuasion of friends induced me to give it a trial.   I com-
menced the use of it,  according to your directions, drinking  freely of
the  dandelion tea.   Before many days, I perceived  its  powerful  effects
on my kidneys, giving me  ease and comfort in passing water—discharg-
ing  large  quantities of gravel and mucus,  aud  by degrees my pain
began to lessen, and  all my distressing symptoms  to  subside,  and in
three or four weeks I could ride in an  easy sulky, by degrees  on  horse-
back, and  in a buggy  wagon, without  giving pain ; and  in eight weeks
I was entirely rid  of  all my gravel symptoms.  I now began to gain
flesh and strength, with a general  restoration  of  my whole system.  I
am  now in perfect health,  and  in the duties  of my office,  as Sheriff's
Deputy of this County ;  can endure as much fatigue, both by  night and
by day, as any man whatever -,  and for this groat blessing, under a kind
Providence, 1 am entirely indebted to your invaluable  discovery, and
hope, for the  benefit of  others  afflicted with the Gravel, that  you may
live to cure thousands, none of whom  can feel more grateful than your
friend and well-wisher,                          Thomas J.  AvEiir.
                                      Middletown, Conn, Sept. 28,1840.
Dr. Samuel IT. V. Lee, New York.
  Dear Sir—I received,  some time since, your package forwarded  by
Mr. Smith,  for which I am  greatly obliged.  I have given the medicine
a fair trial  in a severe case of the gravel, unaccompauicd by any other
medicine, and consider it one of the best preparations for the gravel that
I have ever used.   It acted promptly and decidedly in eliminating the
secretion of urine, and in removing whatever of obstructions existed at
the time.  The patient was a man about 70 years of age, in  whose case
the gravel had for several years been  a very troublesome symptom.  I
discontinued the medicines at his own  suggestion, and he affirmed that
he had no further use for  a remedy to restore the secretion of the urine,
or to remove any  obstruction in its passage.
  I am now trying in a case of  leucorrhcea (fluor albus, or whites), and
make no doubt but that it will succeed equally as well as in the gravel,
and cannot but hope it may answer a valuable purpose in  most of the
uterine and urinary difficulties  for which we are so frequently called
upon to prescribe.   I shall  most cheerfully do what I can to favor the
introduction of your remedy on account of its own merit.
                 Respectfully your obedient servant,
                                             Thomas Mlner, M. D,

               The Extraordinary Case of Mr. Pool.
                                          New London, July 13, 1840.
Doctor Samuel H. P. Lee :
   Dear Sir—I consider it my duty to my fellow creatures, and to you
in particular, to  make known my case to the world, for the benefit of
those who are suffering with the Gravel and  stoue in the  kidneys and
bladder.
   I was first attacked when I was about six years old, with pains across 
19
the small of the back, with spasm down to the neck of the bladder and
along the urethra, frequent suppressions of urine, heat and inflammation
of the bladder, and  constant inclination to pass my urine,  sometimes
every half hour, high colored and bloody.  Hot applications, such aa
hot bricks,  burning brands quenched in water, were often applied to my
back and loins, to promote urine and prevent convulsions.  I had much
sickness at stomach  and vomitings, head ache, loss of appetite, great
weakness, and the above symptoms were always aggravated after taking
cold.  Such were my sufferings, with short  intervals of ease, for about
sixteen years, during which time I was able to attend to some business:
my gravel complaint varying in violence, under the use of  medicines,
but no abatement of my gravel disease.  About two years  ago,  after
taking a heavy cold, I was brought very low, and  entirely prostrated,
with sharp, cutting,  grinding pains in  my kidneys, a dead numbness
down my hips, thighs and lower limbs—urine thick, bloody, mixed with
mucus and  matter very offensive, as if from ulcers; constant and painful
desire to pass water, say from  twenty to thirty  times of a night, for  a
week together; my spasm so severe as to require watchers  to prevent
my tearing myself, from excessive agony, some discharges of small stone
and gravel in bloody urine.  My doctors gave me Carb. Soda, Uva-ursi,
Liquor Potass, Balsam Copaiva, Tincture of Iron, the plant called Buchu,
Black Drop, half an  ounce a night, besides a whole ounce of Elixir of
Opium, sometimes two ounces, also  two ounces of Morphine  in twenty-
four hours  ; one day  I was in such distress that I took an ounce of  Mor-
phine in two hours.
  From December 1838, to October 1839,1 was confined most of the time
to my bed, not being able to sit up more than one hour in twenty-four,
with severe pains, loss of appetite and strength,  sickness at stomach and
same difficulties, with increased heat and inflammation of  the bladder,
taking daily an  ounce of Morphine, but no abatement  of  my gravel
Byniptoms.   My kind and attentive physicians having done everything
that their  medical skill  could devise,  I despaired of ever  being any
better, not expecting to live but a short time.
  In this situation, I was advised  by my friends, and one of my doctors
in particular, knowing its composition, to try your Gravel Specific, as a
forlorn hope, and accordingly placed myself under your especial charge,
on  the 30th October, 1839.  In  three or four days I began  to feel the
effects of your medicine operating upon  my kidneys, giving me ease and
comfort, lessening all my pains, passing and changing the color of my
urine, discharging it more freely, and with it tea spoonfuls of stone and
gravel, from the size of a small pea to small sand, of a light color, some
of it reddish, with sharp  points like broken glass; the milky, purulent
and stringy appearances of  my urine  gradually disappeared, my urine
became pure, free, and no oftencr than in  health, and after constantly
taking your medicine till about the  1st of March, 1840, I  became so
much better as to take exercise in the open air, and continued gaining
my general health, and as my pains gave way, reduced the Morphine to
a trifle, my appetite returned, the sickness at stomach gone, my kidneys
became sound and healthy,  so that I  could lie on one side  as well the
other, which I had not done  for years ; and  now at this present time, I
am entirely free from all  my gravel symptoms; I can lie in bed all night,
am gaining flesh rapidly, and daily growing stronger, and able to do anj 
20
easy work; my kidneys will  bear any pressure, and  my  nerves are
getting regular and strong; I can truly say that I am now in the enjoy
ment of health such as I never before experienced.  Thanks be to Him
who maketh and cureth the disease of the body, and many thanks to you,
by whose medicine I am cured, and I hope all who are afflicted will avail
themselves of your medicine, which I fully believe will always cure the
Gravel in its worst state.
        I am your greatly obliged and faithful friend,
                                                 Jacob  G. Pool.
New London, July 15, 1840.—We, the subscribers, 'hereby certify that
    the above named Jacob G. Pool is a native of this  city, of good
    moral character, and unimpeachable integrity, and the fullest reli-
    liancc may be placed upon his declarations as set forth in his letter
    above.  Many of us were personally acquainted with his sufferings,
    and know that his description is not exaggerated.
                   B. C. Baxter, Druggist,
                   Hon. Elias Perkins,
                   Col. Increase Wilson,
                   Rev. Joseph Hurlbut,
                   Capt. Ebenezer Way,
                   Charles A. Lewis, Esq.,
                   Gen. H. Burbeck,
                   David Coit, Sec, Union Ins. Com.,
                   Hon. John P. Trott,
                   Hon. Francis Allyn, Mayor of City,
                   N. S. Perkins, M. D.
                   Havens <fc Smith, Merchants,
                   Samuel Chany, Esq.,
              /     Rev. Squire B. Hascall,
                   C. J. Allen, Esq., Postmaster.
Extract of a letter from Doctor Isaac G. Porter, dated JVew London,
                    Connecticut, May 4, 1840.
  In reply to your  note of this morning, requesting my opinion of the
safety and efficiency of your medicine for the cure of Lithiasis, or Gravel,
it gives me pleasure to say that I regard it as avaluable remedial agent,
in a large proportion of the  cases of that disease, having witnessed its
beneficial effects, not only upon persons under your care, but also in my
own practice.
  That its efficiency, as  contrasted with ordinary  medication, is owing
chiefly to its  power as a combination, that it is a happy grouping of
medicines, individually calculated to be useful in  the Lithie-Acid Dia-
thesis, and like other combinations, accomplishes  its object with  more
facility and efficiency than would be done by using the same articles
separately, and in succession.                Isaac G. Porter, M. D.
The  case  of John Pierce, Esq., (an officer in the New York Custom
  House),  residing at 88  Warren strest, Brooklyn, JV. Y., in a letter
  to Miss  F. H. of Boston, in answer to the following letter of inquiry,
  Sir—I take the liberty to address to you a letter  of inquiry.   My
mother is  suffering extremely with stone in the bladder ; and  having 
I
21
failed to obtain relief from the skill of our most distinguished medical
men, and having learned that  in a similar case you used the medicine
prepared by Dr. S. H. P. Lee, and  found  benefit from it, is induced to
ask your opinion of its merits.  Will you  have the goodness to state to
me what advancement the disease had made in your case; if it had
really amounted to stone in the bladder, and if you are  really relieved
from its distressing consequences.  Dr. Lee, of Boston (a son of Dr. S.
II. P. Lee), has referred us to you to satisfy my mother's doubts, for  she
is entirely skeptical.  She is now confined to her bed, and has  not  left
her  room for  nine  weeks.  Much  of the time her  sufferings have been
almost insupportable, and I am satisfied if she does not Boon obtain relief
we must ere long be called to the saddest parting earth can witness.
Will you have the goodness to give an early reply.  Please address to
the care of G. IL, Boston,     I am, very respectfully,         F. H.
  Boston, Jan. 18, 1811.

  [Mrs. H*****, whose case is mentioned above, had several attempts
made to break up the stone in her bladder, by Lithotrity, by an eminent
Surgeon, who  was unsuccessful.  The Surgeon recommended her to rely
entirely on Dr. Lee's Solvent,  which she took for six or eight mouths,
and the stone passed off in  Granular Phosphates, and she entirely
recovered, and now enjoys excellent health.   She was under the care of
Doctor Lee, of Boston, No. 18 Hay ward Place.]

                                        Brooklyn, N. Y., Jan. 21, 1841.
To Miss F. H. Boston.
  I  received your  letter of inquiry [dated  the 18th inst.]  yesterday
evening ; and  in reply will stale briefly that I have suffered with gravel
and stone in the bladder  about  18 years, so much so that life was a
burden  to  me;  not a day or night passed but what I had more or less
pain and suffering.  I sought and tried  all  the medicine that was recom-
mended for the gravel, but it all. amounted to nothing more than tempo-
rary relief.  Last winter (1839-40) I was taken down violently with  the
above disease, and through the providence  of GOD, I was informed of the
wonderful cures that had been  performed by Dr. Lee's Gravel Medicine;
I immediately sent  to my friend C. E. Lester, Esq., the collector of  the
customs of the port of New London, and he immediately forwarded it to
me, and its healing power has restored me to health.   I will state accord-
ing to your request, that I have had pass me, since  I commenced taking
Dr. Lee's Medicine, upwards of thirty very sharp and rough stones, the
most of them as  large  as large peas, besides great  quantities of coarse
brown gravel.   This medicine operates upon the kidneys and ]>tod<ler> so
as to dissolve  and bring  away all  those hard substances, and finally to
cure the disease.                                          ,  ..
  Do not hesitate one moment  about taking the medicine ; for it one
word from me could induce your poor mother to take it as I have done,
'* would give  me  great  comfort as I  know it  must cure her ;  quite a
number of our most distinguished  doctors in New York  have used Dr.
Lee's Gravel Medicine, and recommend it highly.
  Excuse this  hasty letter, as I have but a short time before the mad
closes.             Yours, with much respect,
                       John Pierce, 88 Warren St., Brooklyn, N. Y. 
22
 The case of Henry Luce, Esq., as described in his letter  addressed to
  the same person in Boston, who wrote to him as well as Mr. Pierce
  for information.
                             New York [Howard's Hotel], Jan. 22d, 1341.
To  Miss F. H., Boston.
  I received your favor of the 20th inst., asking my opinion of Dr. Lee's
medicine for the cure of stone in the " bladder ;" not being a medical
man, I can only give you an opinion founded on experience in my own
&ase. Having suffered so severely from the effects of instruments and
injections into my bladder, which nearly destroyed me, and being at this
time so providentially recovered, and in a fair prospect of a radical cure,
under the medicine and attendance of Dr. Lee, that it gives me pleasure
to give you all the aid in my power.
  It would be supererogatory in me to say, whether I had a stone in my
bladder or  not, when even doctors differ in opinion on that point, by a
Bounding process  with instruments—but I do  know that after I came
under the care of Dr. Lee, and had taken his solvent a few days, I began
to discharge  quantities of gravel,  small stone, and  pulverized dust,
mixed with muddy mucus, ropy, stringy animal matter, very  offensive,
accompanied sometimes with blood—and that I continued to amend very
rapidly, my pains  in the kidneys and urethra abating—the inflammation
of the bladder [occasioned, I  have  no doubt,  by the twenty  odd ope-
rations of sounding and  injection] subsiding—my hectic  fever, which
had been consuming my flesh for weeks, was reduced from 128 strokes
of pulse to 70 in a minute; my stomach, from loathing and  rejecting
everything, began to retain light food, and now I can eat and digest the
food of a healthy person; my urine improved in color and substance, free
and without any difficulty; my appetite good (too good) ; the tender sore-
ness, everywhere gone ; in short I not only feel like a new  man, but all
the  inmates of the  hotel, since  my return to the  parlor, are remarking
on my wonderful recovery thus  far, and I feel that my perfect restoration
to health is near at hand.  It is about four years since I was first attacked
with calculi, and I have had only  temporary relief from the waters  of
Saratoga aud warm climates; but my complaint this fall', after taking a
great ccld,  completely prostrated  me.  I came to New York, and put
myself under a physician the  28th of Nov., who attended me with his
instruments and injections into the bladder, until I could  endure it  no
longer.  He then told me " I could not be cured," and could not expect
to live but a short time.  At this critical moment, viz : the 23d of Decem-
ber, I was advised to send for Dr. Lee. His skill and Lithontriptic have
restored me already to better health  than I have enjoyed for five or six
years.  I am in daily use of his solvent and dandelion tea, and shall
continue them a month or two longer to divert my Bystem from any cal-
culous tendency, and  I feel  confident that my complaint is conquered.  I
sincerely hope that your suffering parent will commence  immediately
and give the  medicine a  fair trial, and persevere in it to  a final cure,
which I trust is in store for  her afflicted family.
                 Very respectfully, your most obedient servant.
                                                    Henry Luce. 
TS
Copy of a letter from James Lea. Esq., Merchant (of the firm of Pan
  ne'll <fc Lea), Petersburgh, Va., to  Doct.  S. H. P. Lee, JVew  York
  The eminent respectability and standing of the writer will give
  importance to this letter, and consolation to the afflicted, and to the
  community at large interesting intelligence.
                                        Peterdtmrgh, Va., Dee. 6,1841.
Doct. S. H. P. Lee :
  Dear Sir—I  have neglected writing you, perhaps longer than I should
have done, and certainly longer  than I intended; but  I hope you will
not attribute the delay to any want of respect on my part, but to its true
cause—improper neglect and delay, which should not have occurred,
considering the great obligation I necessarily feel under  towards you
from  the great benefits I have derived from the use of your valuable
remedy for the Stone and Gravel.
  You recollect it was the latter part of March last, when I first had the
happiness to become acquainted with you, and was at that time confined
to my room in  New York (Howard's Hotel), from a painful attack of
that most painful of all diseases, the Gravel, or affection of the kidneys,
from which my sufferings have been great beyond description.  My first
attack of that disease was about six years ago, during which time, up to
the period 1 became acquainted with you, I was subject to violent par-
oxysms every two or three months—sometimes oftener, and for which I
had tried the prescriptions  of the most eminent  physicians within ray
reach, and from which I do not know that I derived any permanent bene-
fit—nothing more than temporary relief; and more than nine months ago
I was fully under the impression that I must fall a victim to the disease,
and that in a very short time as the attacks became more frequent, and
were attended with additional pain and suffering, and the usual remedies
affording relief were longer in producing that  effect.  In about four
weeks after I  commenced taking your remedy,  I began to pass gravel
freely, in particles of the size of fine gunpowder to that of a number
over that, which I continued to do daily for six or eight weeks, without
pain or difficulty ; and it is almost incredible the  quantity that I passed
during that period—I Bhould think at least half  a  pint.   My health is
now good, and I think  I  am pretty much if not  entirely relieved from
the disease, although I still occasionally pass small particles of gravel,
 Jind continue occasionally the use of your invaluable remedy, whenever
I feel anything like the old symptoms about the kiduey region.
  For several  years previous to the use^ of your  remedy, I experienced
nearly all the time an unpleasant sensation about the kidney region, and
weakness in the email part of the back ; and when I  would stoop for any
purpose and remain in that position, even for a  short time, for instance
 in  washing my face, when I would again straighten myself it would  be
 attended with  considerable  pain.  These unpleasant and painful sensa-
 tions I have got entirely rid of, and have no attack and but little suffer-
 ing from the disease since your remedy began to  operate.  I have taken
 much trouble to recommend the use of it to others similarly affected with
 myself and I believe it has invariably been attended with the most bene-
 ficial results, where  the  instructions have been attended  to strictly.  J
 could say much more, but you may think I have already been too prolu
 on the subject. I can say for myself truly and with feelings of gratitude,
 that your remedy with  me, has had the  most  happy  effect, and has 
24
relieved me from a painful and afflicting disease, from which I despaired
of relief.                         Yours truly,
                                                     James Lea.
A,  Medical Case of Gravel.—Kidneys in a very advanced 6tate of
  granular disorganization ;  Anasarcal Dropsy, and a train of complex
  and secondary diseases ; Blood highly charged with Urea ; Lithic Dia-
  thesis; Hypertrophy  of  the Heart; Incipient  disease of the Liver,
  &c.; treated successfully at the New York  Gravel Infirmary, No. 36
  John street, with Dr. S. H.  P. Lee's Lithontriptic.
                               Shrewsbury, New Jersey, July 81, 1842.
To Dr. S. H. P. Lee, New York.
  Dear Sir—The sympathy which I  feel for suffering humanity, whose
lot it is to be afflicted with one of the most excruciating maladies mortal
flesh is heir to—the Gravel and Stone in the Kidneys and Bladder—and
to express my gratitude to  you for my recovery  [under Providence]
from that disease in its very worst form, by your medical course, induces
me to address  you with the  history  of my case, aud to request you to
make  it public for the  benefit of the afflicted ; not in a puffing spirit
merely to benefit you, or for the vanity of appearing in print myself, but
from a moral sense of duty towards my suffering fellow creatures.
  In 1838 I began to complain of lassitude and weakness in my limbs
and great depression of spirits.  This was soon followed by a continual
fixed pain  across the small of my back—so severe at times that I could
not put on my coat.  In December, 1840, I began to discharge, with my
urine, bloody mucus mixed with sand, gravel and pebble stones as large
as heads of great pins, with white matter like  pus, very  offensive,
attended with a desire to urinate from 30 to 40 times in 24 hours, accom-
panied with nausea at the stomach  and vomitings, a bad appetite  and
obstinate costive bowels.  In a short time I was obliged to give up labor
entirely; my strong and hale constitution ran down rapidly, I became
depressed and weak, and was obliged to lie in bed much of my time;  a
dull, hanging pain, extending from my back to the shoulders,  head, eye-
balls and limbs.  All these symptoms gradually increasing until the fol-
lowing June, when I became much  swollen in my flesh, over my body
and limbs.  Indentations with the thumb would remain long.  My pains
by turns sharp and severe, with great exhaustion and short breathing, so
that I was sometimes thought to be dying. Under  this state of things I
had the best medical attendance, my kind physicians told me my case
was the worst kind of Gravel disease, attended with consequent disease
of the organs and secretions generally, and usual remedies used without
any abatement of my disease.  I was now advised to consult the Doctors
in New York, and was accordingly brought there in the summer of 1841,
and applied to Dr. Parker, who, on a close examination, pronounced my
disease to  be the Gravel, attended with a diseased Liver, Dropsy. Rheu-
matism and Heart Affection.  At this time,  besides the constant dis-
charges from my kidneys and bladder, I had a swelling on my right side
just below the short ribs, which  on  rubbing or pressing would make  a
noise on my liver like the gurgling of a frog, or wind  and  water, my
heart would palpitate, and my breathing being short, would make such
a commotion in my breast that the striking pulsations were visible acrosa
the room ; my discharges now were to an almost  incredible extent from 
25
the bladder, like  bloody mucns mixed with  brown mud.  and I was  sc
universally swelled that my clothes could not be worn.  Doctor Parker,
with great candor and delicacy, said he felt it his duty to  tell me that I
was incurable, and advised me to return home and  await the result with
resignation ; I did so, and remained without any more doctoring, except
those remedies in  common use, about three weeks, and grew  gradually
worse.
  Unwilling still  to give up  all hopes of relief (for it was only tempo-
rary relief that I hopped or expected  while  I did live), I was recom-
mended to auother eminent doctor in  New York, Doctor Freeman, who
-attended me some  two or three weeks, with some improvement in my short
breathing and  costiveness ; but my Gravel and kidney disease, with the
pains and discharges, gradually grew worse. My kind and  estimable
doctor now told me frankly that my case was so doufctful and unyielding
that he advised me to retun/home;  but at  this juncture your treatise
was put into my hands by Mr. Isaac Rogers, of the Washington Market,
in New York.  I put it into Dr. Freeman's hands and asked his opinion,
whether I should apply to you; he advised me to do so; and Mr. Rogers
having informed me that you had cured him of the Gravel some 20 years
ago, and urging me to call upon you, I laid  aside  my incredulity, for I
was now in almost hopeless despair, and applied to you on the 2nd of
September, 1841.   I  took your medicines and directions  and returned
home, and began upon the course the  3d, and continued most persever-
ingly,  under a gradual  mitigation of all my various symptoms.   For
some  time my urinary discharges were muddy and like coffee grounds,
with the passing of small gravel, very hard, from the smallest size  to
the  bigness of  the head of a great pin.  At length the urine became of
a lighter color, the swelling in my right side disappeared ;  my dropsical
swellings subsided ; my  stomach affection went off,  and  my appetite
began to be good, and my bowels in a healthy condition.   I constantly
grew better, and continued your medicine until the  middle  of May, 1842,
when I found myself so well, and free from every symptom  of complaint,
except muscular weakness, that I began to labor ;  and am now able  to
do nearly as much labor  as any well man.   My urine is perfectly healthy,
clear, and free and natural, and I can  ride without any pain or uneasi-
ness ; and my general health and appearance  is so changed that my
neighbors salute me as one raised from the dead.
            I am your greatly obliged and faithful friend.
                                               Samuel C. Stout.

  Wo, the subscribers, hereby certify that the above named Samuel  C.
Stout is a native of this village (Shrewsbury), of good moral character.
and unimpeachable integrity  ; and the fullest reliance may  be placed
upon his declarations as set forth in his letter above ; many of us were
personally acquainted with his sufferings, and know that his description
Is not exaggerated.
                               I. R. Clark, Minister of the  Gospel,
                               Goodenough Truax,
                               Elhanan Stout.
                               Benjamin Harris,
                               Elhanan H. Stout,
                               Milton  Ely,
                        2 
26
A Severe Case of Gravel.—Very advanced disorganization of bott
  Kidneys ; Granular Elimination of Calculi, accompanied with Hamia
  turia and Mucophosphatic discharges ;  derangement of the digestive
  organs, nausea, costiveness, abdominal  and nephritic pains, oedema
  tous swelling of the feet and legs,  frequent micturation of urine, pulse
  90 to 100 and feeble,  great prostration of muscular strength, great
  exhaustion of fibrin of the blood, pallid  countenance and tongue ; and
  other secondary affections incident to an exhausted constitution, &c,
  &c.  Cured  by a  course of Dr. Lee's Lithontriptic, as may be seeu
  from the following letter from  the Patient.

Doctor S. H. P. Lee,           }              West Farms, Nov., 1842.
         No. 36 John St., N. Y. ( "
  Sir—Having recovered unexpectedly from that dreadful disease the
Gravel, by your invaluable medicine, I fVel a desire that every person
laboring  under the same disease should avail themselves of it.  If you
have any patients that are despouding, tell them not to be discouraged
in the  least—only persevere,  liiform them of my case.   There was no
person bronght nearer the grave  with any disease, that ever  recovered,
than I  have been with that ; and  it is your medicine, and  that alone, in
the  hands of Him that can kill and  make alive again, that has restored
me  to my usual health.
                I am your greatly obliged and sincere friend,
                                                    Anna Mapes.

                                            Neic York, Nov. IS, 1842.
  The above letter having been exhibited  to me, from Miss Mapes, I beg
leave to state that  I am  personally acquainted with her, and know her
to be a lady of good character  and integrity, and  the fullest reliauce
may be placed upon her statement.
                                    W. Beach, M. D., 223 Bowery.
  gSt' Further information touching this extraordinary  recovery may
be obtained by calling on Dr. W. Beach, 223 Bowery ; Benjamin Mapes,
No. 130 Monroe Street; or at Dr. Lee's Infirmary, 36 John Street.

          Extract of a Letter from the Rev. Mr. Wood.
                             Middletown, Orange Co., N. Y. Nov. 29,1842.
To Dr. Samuel H. P. Lee :
  My Dear Friend—I have now used your Lithontriptic Medicine two
months, agreeably to directions  ; since taking them all  the distressing
symptoms have ceased.  1 have  no pain in the bladder, and none in the
ureters.   The  secretiou of urine  is in a proper quantity, and as far as  I
can see,  natural and right. The irritation  of body with which I  /vas
afflicted  is gone.  My flesh and  strength  have greatly  increased.   My
appetite  is now uniformly  good.  I have no acute  pain  anywhere.  A
slight weakness in the small of  my back, of which  I should  scarcely be
conscious, if I had not once passed a small stone, is the only thing which
reminds  me that there is probably in my kidneys a tendency to gravel.
   Your medicine is the only thing I have taken, and am confident it  is
 the best  remedy known for my disease.   I am  most  thankful  to GOD for
 your acquaintance, and for your medicine, with a thousand thanks for its
 great good to me.  I wish you to send me two more bottles. 
27
  I ought to say to you that I had not enjoyed a day of comfort for two
years, until I used this remedy.  Such was the constant uneasiness about
my whole system, and the distressing pains about the neck of the bladder,
the derangement of the whole urinary system, that I never supposed my
health could be again so  good as it now is.  Indeed, I  am uow strong
and competent to perform my parochial duties all day as I  ever was:
but the fears induced by such a miserable disease breaking in upon the
constitution are such  as would make a hypochondriac of any but a
Christian, and  he would  need much  grace  when  cured not to have
apprehensions still.
  The child of Mr. Edward  Stewart, which was brought to your office
last August in such  a  miserable condition, is, and has been for  a long
time,  to appearance,  enjoying perfect health.
    I am, with great  respect and thankfulness, sincerely yours,
                 Daniel P. Wood, Pastor of the Presbyterian Church.
                                            New York, Jan. 10, 1848.
Dr. S H. P. Lee, 36 John street :
  Prompted by a spirit of gratitude, for the cure you  have effected in
my case, I  send you  these few lines, hoping it  may be  the means of
inducing others similarly  afflicted to avail  themselves of the means
which have proved so efficacious to me.
  It is now four years siuce I was first afflicted with the Gravel.   I have
been attended by four physicians, and grew worse under their treatment;
their prescriptions proving merely palliative.  In fact, your predeces-
sors did not seem to understand my case, calling it everything  but  the
right name—such as Kidney Disease, Rheumatism, Dyspepsia,  Catarrh
of the Bladder, Nervous Irritability, and Inflammation.
  I have taken four bottles of your Lithontriptic medicine, and followed
your directions strictly about five  months, and I trust I cau say it has
effected a  radical cure.  My general health is restored, and my local
disease has entirely disappeared.
  If my testimony in behalf of your skill in this distressing disease shall
contribute  to lead  others  to avail themselves of it, I shall be much
gratified.
    I remain, with sentiments of regard and respect,
                Margaret D.  Lloyd, 16 Stanton St., or 3 Prince St.
                                    West Springfield, Mass. Jan. 1,1848.
Doct S. II. P. Lee :
  Sir—I take this opportunity  to communicate  to  you  (through  the
blessing of GOD  aud your instrumentality) my perfect restoration to
health, after suffering for eight  years all the  miseries of that dreadful
disease, the Gravel.  As you know all the particulars of my case. I givo
you my name to make use of for the public good, as you shall see fit,
simply adding, that I do  believe, and my frieuds all say the same, thai
I must have been in my grave  ere this, or possibly had a painful  life
prolonged without even one day free from pain, had I not taken youi
invaluable  Lithontriptic ; and I  do  not hesitate  to  say, candidly aud
frankly, that I have not a doubt but your medicine will cure even  thi
most severe aase.           Yours, gratefully and respectfully,
                                               Fanny C. Morgan. 
28
Extract of a Letter from a gentleman to Commodore Cunningham
         (sitting on a Court Martial in J\*ew York) dated
                                       Norfolk, Va., October Sd, 1342. _
  Dear Sir—I am extremely obliged to you lor Doctor S. H. P. Lee'a
pamphlet and certificates, sent on by Mr. Hopkins and  Com. Wilkinson,
all of which I have read, relating to the cures performed by Dr. Lee in
cases of Gravel and kidney diseases.
  I will give you the history of my disease, which you will oblige me by
showing to Dr. Lee, and if he thinks his medicines are proper in my case,
I will thank you to get him to send on the medicines by the next Satur-
day Norfolk Packet, and  I  will direct  our House in New York to call
and pay him for them.
  About seven years ago, in travelling from this place to  New York,
(the rivers  being closed with ice) I was forced to take the  land route
from Annapolis, Md., through Maryland and Pennsylvania to New York;
there  being much snow on  the  ground, I  caught a very violent cold.
After getting  to the  city, for about two days I was busily engaged in
purchasing  goods, and  about the evening of the second or  third day,
after coming down a long flight of stairs (the rooms above being  occu-
pied by an importer), I felt  something give way about the region of the
kidneys, which produced considerable weakness and some pain.   1 soon
after went to my hotel, and  at bed-time, in taking up a chamber to uri-
nate I passed a great deal of blood, accompanied with pain; I sent for a
physician, but in the meantime the pain  became almost distracting, occa-
sioned, as he said, by the passing of some substance through  the ureter
from the kidney to the bladder.   I was several hours in passing—mean-
time I was kept in a vessel of water as hot as I could bear it—that caus-
iug a relaxing of the parts, and in some degree lessening the pain, which
was nevertheless excruciating in the extreme.  I was sick for some weeks
in New York, and my physician, who  attended  me, then told me that it
was more than probable  that I would  be periodically  affected in like
manner, which I have found to my cost has been truly verified.   I have
not since that time passed  any blood,  but if I take any very active or
fatiguing exercise—if imprudent in diet—if 1 take cold, I am soon after
taken with great weakness and pain in the small of my back, and begin
to pass a great deal of matter or pus, occasionally with blood in it, which
causes a most fiery burning through the urethra and the penis, with a
desire  every half hour or so to pass water, and which does not exceed,
very frequently, more than a few drops in passing it.  The burning
is so intense that it is  scarcely bearable*  It will remain on me until I
find temporary relief from my physician, and probably in less than two
or three weeks will return  again as bad as ever.  This burning is so
xeverely painful, that  it affects my spirits, produces lassitude, and a
iisposition to be alone and away from everybody.
   Dr. Higgins thinks that the kidneys are inflamed, and that the inflam-
mation produces an abcess, which in its discharges (the  matter beinii
Acrid)  causes the canal to become raw, thereby producing the most \\<y
lent burning.  The pain is  exceedingly severe  at the  extremity of the
glans penis. One thing is certain, my kidneys are much affected—I have
much  pain and weakness in the small of my back, a violent  burning
(when affected in passing urine), and the passage of a large quantity of
corrupt matter causing pain in the urethra. 
29
  And now. my friend, if on showing this hasty account of my diseasa
to Dr. Lee, he thinks he can do anything for me, for : am rapidly wear-
ing out, and must ere  long give  up  all that life can give, you wili
please get him to forward  the remedy as above, to  care of Messrs Paul
<fc Pegrain, Norfolk, Va.
                     I remain your friend, truly,
                                             Edward S. Pegram.
  In this  case, the medicine was sent immediately, agreeably  to  the
writer's request, and the result may be seen by his letter, under data
March  16th, 1843.
  N. B. February 20th, 1849—Mr. Pegram, at the Oity Hotel, in New
York, informed me he was in perfect health, and entirely free from  the
disease which is described above.
Extract of a Letter from the same to Dr. Lee, dated March 16, 1843.
  I commenced taking your medicine in October last agreeably to direc-
tions, first preparing the system by a cathartic of your Bilious Pills;
and I am pleased to say, that before I had been taking the Lithontriptic
one week, the beneficial  effects were most manifest;  and after pursuing
the course recommended by you, three or four months, I have not  been
confined to my house  a  single day from my kidney affections since. I
believe, judging from my own situation, that you  have discovered a
specific  for all kidney or gravel affections,  and do  most  confidently
recommend it to all persons afflicted with those most painful  diseases.
                               I am, yours most sincerely,
                                              Edward S. Pegram.
                   A  Severe Case of Gravel.
Advanced disorganization of the Kidneys and Urinary Organs, Func
  tional derangement of the Secretory System, and its attendant conse-
  quences,  Universal Dropsy,  &c.,  &c.   In a  Letter  from Captain
  Nathan Davis.
                                            New York, May 22,1848.
Dr. S. H. P. Lee :
  Dear Str—I consider it to be my duty to communicate to the world
the extraordinary recovery in my case, so unexpectedly to all my friends
and acquaintances.   But  for your invaluable remedy for  the Gravel, I
must, in all human probability have been, ere this, consigned  to the
grave ;  it is for the benefit of  sufferers that I now make  the following
statement:—
  In the year 1830 I was  attacked with  pains in the small of my back,
shooting to the hips and bladder, with frequent and painful inclination
to urinate.   These attacks would occur once in a month or two, or every
time I  took cold;  my urine  would deposit mucus matter and a red,
gravelly sediment, sometimes bloody, with sharp grinding pains at the
neck of the bladder, attended  with sickness at the stomach, and great
depression of spirits.  About six years ago, all those symptoms became
aggravated with  occasional  suppression of urine, and I was obliged to
use the catheter to draw off my urine ;  costiveness of my bowels, weak
ness in the small of my back, and pains in stooping,  with  deranged
digestion and gradual swelling of my feet and legs, seemed to baffle the 
30
remedies prescribed for me by. my physicians : I gradually grew worse,
with turns of great suffering  and misery, until last August, when I wa»
compelled to quit business, and was constantly attended by an eraine.nl.
physician. Dr. K----, until the last week in January, when all my com-
plaints had arrived to a condition that threatened the extinction of life
at every hour ;  I had not been able to lie down for near two months-
dropsical affections had made  6uch advances, together with the pains in
my kidneys and at the  neck of the bladder, that.I could get no sleep,
only by being supported by my watchers in a recumbent position in an
easy chair ; and such were the universal swellings of my body and limbs,
that four inches above  my knees the circumference of  my thighs mea-
sured thirty-two inches, and the skin was ready to burst in many places ;
there was such  an effusion of water in my chest that my breathing was
the most difficult and distressing;  pay pulse  became irregular, and my
heart would palpitate as if compressed  on all sides ; my stomach and
bowels seemed to lose all power,  and I was very costive, and my abdo-
men swelled enormously—my pulse became weak and  quick—my head
light and distressed, and in this  condition death seemed almost desirj
able. My physician, who had been very kind and  attentive, now gave
up all hopes, and left me, supposing I could not live many hours.  lie
Baid no more could be done.  In  this  situation I was  advised by Mrs.
Ashby, No. 220 Washington Street, and Mr. Isaac Rogers, who resides at
346  Greenwich Street, to  send for you.  On the first of February you
first visited  me. and found my friends around me,  who thought I was
dying—I was at the worst, and could scarcely speak in whispers—you
commenced  giving me  your invaluable  Lithontriptic and cathartics to
^radicate the water, and although the evacuations were very large and
exhausting,  the Gravel Pills  seemed to  give me  new and reviving feel-
ings ; I began to mend  and get relief—my legs burst open and discharged
freely ; and my urine became more free and less bloody, the purulent
offensive matter in it  became less, and  my appetite  returned, and in
three weeks there was such an abatement of all my alarming symptoms,
that I  could lie on  a bed without suffocation, the first time for three
months.  1 continued to mend rapidly, and  could then walk about my
chamber; and  but for a tightness in my breast, I became comfortable.
By the middle and latter part of March, my dropsical  swellings nearly
subsided, my legs discharged freely, and my urine began to  be natural
and free.  I continued from  that time to this present date to recover
from all my complaints—the  dropsical  swellings have  all  disappeared,
and my legs healed, the flesh solid and natural;  my urinary discharges
natural and regular, my appetite good, my general health better than it
was fifteen  years  ago  ; indeed, I consider myself almost miraculously
snatched from the  grave, and it is with feelings of  gratitude, that  your
remedy, with me, has had  the most  happy effect in relieving me from a
disease from which 1 or my friends despaired of relief even, much  more
Df a recovery.  I am fifty years of age.  I ought to mention that soon
after you began to visit me, Dr. Beakley, at  the Astor House, called to
see me  with you, and gave me great encouragement as to your Gravel
Medicine, he having taken it  with good effect in his own case.
                   I remain your most obliged friend,
                                        Nathan Davis,
                            Corner of Greenwich and Vesey Streets. 
31
  We,  the  undersigned, were eye-witnesses to the  sufferings of Capt
Nathan Davis, as related in  the  foregoing letter, addressed to Dr. S. H
P. Lee, and we consider his recovery as almost miraculous.
                Theophilus Civill, No. 92 North Moore Street,
                Samuel S. Sweet, 279 Greenwich,
                Cornelius White, 98 Vesey,
                S. H. Johnson, 98 Vesey.
                Gilbert C. Baylis, 131 Prospect St., Brooklyn,
                Wm. Van Pelt, 98 Vesey,
                Francis Andrews, 214 Fulton,
                Abraham  Cotrell, 127 Suffolk,
                Reese & Miles, 260 Fulton,
                Wm. H. Jacobs. 250 Fulton,
                Isaac Rogers,  346 Greenwich,
                Henry Wright, 94 Vesey,
                John C. Buck, 76 Nassau St., Brooklyn,
                John Tenbrook, 108 Forsyth,
                Theodore S. Parker, 39 Jay,
                James Van Gelder, 240 Washington,
                Peter Spader, 44 Bedford,
                Allen Johnson, 56 Laight,
                John Ball, 104 Barclay,
                John C. House, 75 Barclay,
                John Forsyth, 227 Washington,
                W. H. Miller, 185 Pearl,
                Stephen Haley, Jr„ 203 Duane,
                R. N. Eldridge, 220  Washington,
                Joseph B. Guyre, 575 Broadway,
                Robert Wilson, Rockland County,
                Thokne Walling, 243 Washington,
                Jesse Crandall,  311 Grenwich,
                John Conner, 233 Greenwich.

The following letter from William Tyack, Esq., Port Warden, in answer
   to inquiries touching the  above case, will be interesting to those who
   arc acquainted with this well known  philanthropist.
                                            New York, May 27,1843.
Doctor S. H. P. Lee :
   Sib—On the 31st day of Jan. last, at two o'clock in the morning. I was
calkd  up to witness the departure from this mortal life of Capt.. Nathan
Davis. The messenger said, come quickly, he is dying!   I found him to
all appearance, a dying man ; his  disease was the  dropsy,  originating
from the  Gravel and disease of the  Kidneys ;  he was  sitting in an easy
chair supported by the watchers, not having lain down for over sixty
days and nights ;  I having  visited  him several times every  twenty-four
hours during this period ; he had no use of his hands or feet, no pulse
visible ; his chest was filled  nearly to suffocation by water, his breathing
was short, and kis distress and groans I cannot describe—his extremities
were cold and  benumbed, legs and thighs, and  the whole body swelled
enormously ;  his legs burst open in several places—I applied  warm appli-
cations and stimulants  until the arrival of the family physician, who
attended promptly notwithstanding the severity of the  night, and no 
32
gentleman in the profession stands more deservedly high.  He  arrived
at 4 o'clock, and after examination of his patient, and approving what I
had done, said he deemed it his painful duty to inform Mrs. Davis, that
her  husband was fast approaching the fatal hour which must separate
them ; that he could not survive past  nine o'clock, and  that I might con-
tinue as I had done, according to my judgment and his wants; I con-
tinued the applications; yet there appeared no hope.   At this  critical
hour we were informed of the extraordinary success which had attended
your practice in these dangerous  diseases; your immediate arrival and
commencement in this case, and the success attending it, was so fortunate
and  rapid, that in less than forty  days, he was able to  lie down  in bed ;
and  at this present time, although continuing to take your invaluable
Gravel Medicine, as a restorer of his constitution, he is able to be about
his usual business, enjoying good aud  better health than I have seen him
for many years.  I have visited many of the hospitals in this my native
country, and also many in Europe, South America, and the West Indies,
not as a medical man, but as a citizen of the American Republic, who
deems it not only a privilege, but a duty, to gain all the information in
his power to  save from the grave any of the human family who may
need his feeble aid in time of distress.   I have seen the sick and dying in
all situations, but I must in candor  say, that in this instance of Capt,
Davis, I consider his recovery as the most extraordinary I ever witnessed.
              William Tyack, 240 Washington Street,
                                Master Warden, Port of New York.
            Case of Hematuria  from Calculi.
  Miss S----, of  Boston 38 years old, cachetic habit, was attacked in
the month of  May, 1840, with a discharge of blood from the urinary
organs, attended with a pain and a sense of weight in the region of the
kidneys and bladder, preceded by a  frequent inclination to  micturition
which followed her up every few days, till the month of August.  From
the month of  August to the 26th  of October, 1840, the disease became
aggravated with daily and  constant discharges of blood with the urine.
The catamenia had ceased.  She  had been complaining for five years,
more or less, with a pain in her side, heat and burning in the stomach,
palpitation and costiveness.  She applied to the Gravel Infirmary on the
26th October, 1840, and was put on a course of Dr. S. HP. Lee's Solvent,
which immediately gave her relief,  and after taking this remedy five
weeks, the causes of irritation were  removed, and the system brought
round to a state of healthy action.  She is now, andhas been ever since,
in the enjoyment of good health.  Reference to  this person can be had
by applying to the Gravel  Infirmary, No. 18 Hayward Place, Boston.
             Case of Irritability of the It ladder.
Miss----, of Boston, had suffered for seven years with an irritability
of the bladder, accompanied with frequent and difficult micturition,
from fifteen to twenty times of a night, and a great frequency during
the day, with pains and spasms in the region of the bladder, depositing
large quantities  of mucus, of the consistency of jelly, mixed with the
uriuc.  The cause was supposed to be a stone in the bladder.  The blad-
der was sounded a few years ago, but no stone was found.  She under-
went a great variety of medical treatment for several years ;  two issues 
oJ
were made in the region of the  bladder, which were continued open sis
months, but derived no relief.  The general system had become derar-ged
She commenced the use  of Dr. Lee's Solvent in January, 1841, and
began  immediately to obtain relief, and by a steady perseverance n
the use of it  eight months, with  an intermission of two months, *b»
gained health, flesh and strength.
A case of Stone in the bladder, of an interesting boy, six years of age
  cured by Dr. S. H. P. Lee. of New York, with his Lithontriptic medi
  cine, as related  in  the following Letter from the Rev. N. A. Pratl
  residing in Georgia.
                                  RosweU, Cobb Co., Ga., Nov. 18, 1844.
Doctor Lee :
  Dear Sir—Your letter of the 1st inst., is before me.  I proceed to givd
you a concise history of the case of my little son.  Symptoms of gravel
or stone  were discovered in him at a very early age.  Before he wan
nine months  old, he was subject to fainting paroxysms, induced appa-
rently by pain ; but where,  or of what character the pain was, we could
not ascertain in one  so young.  At  the  age  of  thirteen or  fourteen
months, he passed bloody urine, which revealed  to us the alarming fact
that he was afflicted with the gravel or stone.
  His paroxysms of pain, however, as he advanced in age and size, were
not distressing.  They did not interfere with  his appetite or general
health, but still he  gave frequent evidence that the disease was there.
  When he was about three years old, I  took  him to Gwinett Co., to
Doctor Wildman, a distinguished surgeon  and lithotomist, who sounded
him, and  pronounced the stone in the bladder as large as a chestnut.  He
said that as the pain was not troublesome,  and as the boy was quite  fat,
it would  not be best to have the operation performed under a year ; but
that sooner or later it must be done.  During this year, his pains became
more frequent, and he became  somewhat reduced,  though still his gene-
ral health was good, and his pains were generally relieved by a tepid
bath.   It was the winter after he was sounded, that is, the winter of 1841
and '42, that  I saw and stated his case to you.  In January or February,
1812, we  commenced your Lithontriptic under great disadvantage, as we
were compelled to dissolve  the pill in honey, being unable to induce him
to swallow it whole ; when the  first bottle was gone,  it was some months
before we could get another,  and when the second was used  it was a
whole year before  we  could procure  a supply.  That which you sent,
you remember, remained at Savannah twelve  months before we could
near what had become of it.   It was  not  till December,  1843, that wo
began to use your medicine to any advantage, aud  according to your
directions.  From the time we got a supply, we gave him two or three
pills a day, until March, 1844, when he passed a  stone as large as a
bean.
  1 did not weigh it at the time, but months afterwards it weighed about
eight grains.  It was then very dry.  Some weeks  previous to the pass-
ing of this stone his pains were at times distressing.   We were compelled
to resort to  the  use of laudanum and  morphine for relief, and during
the whole day when it was discharged, his pains were excruciating, and
when it was passed, his eyes sparkled, and he said in raptures, " Mother
ant you  glad.'"
                                2* 
34
  YK conttu.ied the medicine, in smaller quantities, for a few weeks, and
then Jisconunued  it altogether; since which time  he has not had the
slightest symptoms of  the disease.  He is  cured!   He is now a lively,
healthy boy.'                                   •
  I would strongly recommend  to any one, old or young, afflicted with
this painful complaint,  to make  a faithful trial of your medicine before
submitting to the dangerous operation of the knife.
  For  myself, I am thankful that I was directed to you;  and my little
oov will remember Dr.  Lee as long as he lives.
  Vou are at liberty, my dear sir, to make what use you please of the
foregoing statement.        Very respectfully, yours,
                                              Nathl. A. Pratt.*
  To Dr. Samuel H. P. Lee, 78 Nassau Street, New York.
   * Reference to Dr. Lines Pratt, No. 50 East-Broadway,  and 109 Henry
 Street, New York.

   The case of Mrs. S., of Essex, Middlesex  County, Conn.  Vesicular
 Calculi and Stone in the Bladder, with its train of constitutional distur-
 bances,  such as nervous and  muscular debility,  morbid  secretions,
 cachexy, kidney disorganization, lithic"diathesis, <fcc.. &c.  In her letter,
 she states as follows:
                                            Fssea, Ct., Aug. 25th, 1845.
 Doct. S. II. P.  Lee:
   Sir,—I received your letter, requesting a short history of my disease,
 the effect of your  treatmeut, and the state of my health at the present
 time.
   I was first affected with great weakness in the lower part of my bowels,
 attended with considerable  pain and great pressure, some  pain in  my
 back directly opposite, accompanied with an almost constant discharge
 of thick mucus, very offensive, which debilitated me so as to confine me
 to my bed.   I applied to different physicians, who seemed  to  agree in
 the opinion that my disease  was an irritation  of the bladder, the urethra
 being much swollen,  causing  great  pain  at  every  discharge.   The
 extreme pressure I suffered they supposed to be the falling of the womb.
 After prescribing various remedies, which I strictly  attended to without
 effect, I was advised to try your medicine, which I accordingly did, and
 after taking one bottle of your Lithontriptic  I became discouraged,
 thinking it did me no good; but my  father being anxious for me to
 resume it, and perceiving upon close examination of my urine  particles
 of sand and gravel, which convinced my physicians that it was entirely
 calculous, they advised me  to put myself under  your care immediately,
 which I accordingly did. and commenced again  taking  your medicine,
 and after taking four bottles without relief  I considered my case  hope-
" less, and was on  the point of giving it up again ; but I had commenced
 on the fifth bottle when I discharged, after the  most excruciating pain
 and agony, the large stone  I sent you.*  Since that time, my health  has
 been better than for two years past; I can now walk, ride, and attend to
 my domestic concerns without any of that pain or pressure, or any thing
 of the kind that I formerly  suffered.
   Nothing now prevents my enjoying good health, excepting an  impaired
 constitution, which I think might have been prevented, had I resorted 
33
to your Solvent Medicine sooner ; I still continue taking your medicine
occasionally, and shall pay a strict regard to myself and your medicine ;
and 1 would recommend  to all similarly affected to resort to this same
remedy, and persevere in it, for I am convinced that nothing else has
saved my life, and restored me to my present state of health.
                  Yours respectfully,                    H. Smith.
  "This  stone  may be seen at Dr. Lee's  Infirmary Office, 78 Nassau
Street.  It measures one inch in length, and three-eighths in breadth.
Extract of a Letter from the Hon. Roger M. Sherman, L. L. D., Chief
  Justice of the Superior Court of Connecticut.
                                             Fairfield, Ct., Jan. 1848.
  My Dear Sir,—I received your letter of the 30th ult., by last evening's
mail,  inquiring as to the state of my  health and  the influence of  the
medical course I am now pursuing under your advice.
  I am happy to have it in my power  to say, that although my disease
still coutinues,  yet its severities are greatly mitigated, and I am con-
stantly but gradually convalescing.  These  results  I  attribute to your
medicine,  and have flattering hopes that, by perseverance, I shall ulti-
mately experience a cure.
  I subjoin  my  check for ten dollars, for  which  please send me twc
bottles more, by  the captain of one of our Southport Packets.
                           Yours, very respectfully,
                                             Roger M.  Sherman.
The  case  of Benjamin Buck, Esq., of Baltimore, an eminent Shipping
  Merchant.  Albuminous Urine, Lithic Diathesis, Granular Elminations,
  and Disorganization of the Kidneys, with great constitutional distur-
  bance.
                                            Baltimore, Dec. ZUt, 1841.
Doctor Samuel H. P. Lee, New York :
  Dear Sir,—On the 2nd inst., I received and commenced your Gravel
Medicine according to the directions in your pamphlet; I am happy to
inform you that I am  as different a man in point of feelings as it is possi-
ble to conceive, and my friends say in appearance also. I have entirely
lost  all pain in the bladder, and  pass my urine better than I have been
able  to do for twenty years, during which  time I have been suffering with
this  most  distressing  of all  complaints, the gravel; my pains were at
the neck of the bladder, sometimes almost past endurance, attended with
stricture and a constant disposition to make  water,  sometimes ten  or
twelve times an hour; my urine  thick  and muddy, high colored, with
stringy subtances, with deposits adhering  to the chamber like brickdust;
sometimes I was dyspeptic,  the disease  varying  in violence.  The last
two  or  three months, I have been confined  to  my house almost all thu
time, under treatment of our best physicians, without benefit.  I have
Buffered much from  suppression of urine, when I took cold,  and from
despondency and general weakness.
  1 assure you nothing would afford  me  more pleasure than now to be
able  to bear testimony to the astonishing  benefits resulting from the use
of your Lithontriptic  Medicine in  my case, and I consider it a Providen-
tial  interposition  that I was directed and advised to apply to you ; and 
36
you are at liberty to make use of my name for the benefit d tl"» dieted,
and I shall feel it a pleasure if it will benefit you.
  May  you  long live to be the  happy instrument  in  relieving pro«
suffering humanity of such distressing afflictions is the prayer of
                Your most obed't. servant,
                                Benjamin Buck, 75 Smith's Wharf.
 Extract of a letter from a lady, dated Liverpool, England, March 3
            1841 (32 Percy Street) to a lady in  this city.
  Please say to Dr. Lee, that his  Lithontriptic Medicine, for Nephritis
Complaints, has been of the greatest service to me, and that  I owe verj
much of my preseut health to him, whose acquaintance I shall always ba
happy to have  made.  I wish the Doctor would send me, through Messrs
Goodhue & Co., four  bottles more, to care of Baring, Brothers, & Co.
Liverpool.

         Copy of a letter from Doctor Long, to Doctor Lee.
                                            Springfield, Oct. 18, 1845.
  Dear Sir—I have the satisfaction of  informing you that the Lithon-
triptic succeeds well in both cases I wrote to you about.  The man, Mr.
Lathrop, is quite  free from pains, and can earn his living, doing  light
work, and the daughter has began to work in the mills.  I think both will
be cured.  They are very grateful for your kindness, in reducing your
prices to their means, and  I  am so well satisfied  of its utility  in both
these cases, that I have concluded to  advance for them, and to continue
him especially under your treatment, until the lithic diathesis is destroyed.
I send you  herewith the money for three bottles for them, and also pay-
ment for one bottle fot myself to experiment upon.
                     Yours truly,             Lawson Long, M. D.
  Henry S. Lee, M. D., Boston.

                              Bedford Cowity, Virginia, April 8th, 1845.
Doctor  Samuel H. P. Lee :
  Dear  Sir—I feel it to be a duty which I owe, not only to you, but to
those who may be so unfortunate as to be afflicted with those most dis-
tressing complaints, the  Stone  and Gravel, to state the happy effects
which I  have experienced from the use of your Gravel Specific.  I  am
now seventy-six years of age, and, notwithstanding my general health
has been good, I have for the last twelve  or fourteen years been severely
afflicted with the stone and  gravel.  Upwards  of 12 months ago,  I heard
of your  '• discovery of a solvent remedy " for those painful diseases, and
having tried various remedies, and several  seasons at  our Springs,  with-
out experiencing more than temporary relief, I determined to give your
medicine a trial.  I accordingly tried  one bottle, and commenced the use
of it about twelve months since,  and I can confidently say, after using a
second bottle, that I am perfectly cured.  I experienced immediate  relief
from the commencement of taking  it, and in a short time it brought  away
  entities of sand and pieces of  stone ; and after  having waited a suffi-
»Wnt length of time to see whether there  would be any return of my dis-
ease, I think I may say that I have sufficiently tested its virtues to say
ttiat your Specific has  entirely cured me ; and although I feel confident 
37
that a cure has been effected in my case, I intend  to keep a constant
supply of the Specific by me.  Nothing would  induce me to be without
it.                               Your obedient servant,
                                              Joseph Slaughter.
  To Samuel H. P. Lee, 78 Nassau Street, New York.
                              Fryburgh, Oxford Co., Me., March 18,1845.
Doctor Samuel H. P. Lee :
  Dear Sir—Having been in the practice of Medicine in this town and
vicinity for more than twenty years, and  seen many cases of Stone and
Gravel in the kidneys and bladder, and some of them  terminate fatally ;
and having for several years past seen the wonderful operation of your
Lithontriptic in those cases,  even  on  my  own patients, I am induced to
write  to you in behalf of a patient now under my care, in an adjoining
town  (Denmark).   For several years past  he has been afflicted withDysu-
ria, and for months has been confined to his  bed with stone and  gravel,
enduring the most excruciating  pain in the kidneys and penis in voiding
his urine, which, for many weeks, has not passed without introducing the
catheter.
  When I  first called to see him, I recommended, as the only remedy
which promised the  least hope  of success, your solvent for gravel, and
procured about one-third of a  bottle  of  a man (who  had used it by my
recommendation successfully), and he has already been much relieved
by this small portion of  the remedy, and now passes urine without the
catheter, and with  much less pain than before taking it.  This is a well-
marked case of Lithiasis of the lithic species.  I wish you to send me a
bottle of your valuable Lithontriptic for him, directed as above.
  You know nothing of me,  of  course. John S. Barrows, Esq., who has
had two bottles of your medicine, and has been perfectly cured by it, is
a relative of mine.  You can inquire of Thomas Fessenden, Counsellor-
at-Law, No. 16 Wall Street,  in your city, of my character and standing
in Maine.
      With much respect, I  am your friend and obedient servant,
                                            Bcel Barrows, M. D.
Extract from a letter of Dr. Barrows, dated Fryburgh, Me.,  March
          20th, 1851, addressed to Dr. Henry S. Lee, £osto?i.
  "I  procured from your father  and yourself several quantities of his
Lithontriptic medicine, 'some years  since,  and used it successfully in
every instance.  There is a patient of mine now suffering severely with
LithiaBis, which  would, I think, be removed  by the application of his
valuable solvent.  Please send me some by Express, &c."
The Case of Mr. Morrell B.  Spaulding, Merchant, JVo. 15  South
                         Street, JVew York.
                                           New York, Dec. 22rf, 1845.
Doct. S. H. P. Lee :
  Dear Sir—I received your note, requesting a short statement  of my
case, and cure under your treatment, to be inserted in a new edition of
your treatise on calculous diseases, &c., «!fec.
  If all your  cases of severity have terminated as successfully  nnder
your Lithontriptic practice, as mine has, and were to be inserted in your 
38
book, it would, I think, become a volume of ponderous size.  Althougl
I have a repugnance to appearing in print in a medical way, yet I feel it
to be a duty 1 owe to you, and to my fellow sufferers with  the Gravel,
especially to such as are skeptical  on  the  subject of a remedy for this
distressing and desponding disease--a skepticism founded on the common
opinion of medical men that there  is " no  cure "—to make known for
their benefit my  aggravated case and  cure  by your invaluable remedy,
without which, in all probability, I should be now either suffering most
grievously or gone to the silent grave.
  About seven years ago, I was attacked with a derangement of my kid-
neys and their relative organs, followed by the usual symptoms of gravel
with severe pains from my  kidneys  to the neck of the bladder, with dis-
colored, muddy, and sometimes  bloody urine, with painful and frequent
inclinations in discharging it.   1 had frequent deposits of red sediment,
combined  with mucus and pus,  burning heat in the prostate gland, with
chills and sometimes lingering fevers, with furred tongue, costive  bowels,
and great weakness, so  as at times to  render me unfit to attend to busi-
ness.  My general health and constitution gave way, my spirits  became
depressed, and after trying every remedy usually given for the  Gravel
without relief, I was advised to place my case in your hands.  I did so,
and after taking  nine Bottles of your solvent, and observing the direc-
tions  and rules in your book, I  found myself  in  twelve mouths a well
man, and  free from all my old  complaints of  the kidney  and urinary
organs ; and  next  to all due thankfulness to the Supreme Being, I feel
under everlasting obligations to you.
  If any  are suffering, and are disbelievers in a perfect remedy for
Gravel and the painful symptoms attendant upon such diseases, tell them
to call on me for my sympathy and advice.
                       I  am, very truly, your obliged friend,
                                          MORRELL B. SPAULDING.
                        Clappville, Worcester Co., Mast., October 5,1341.
To Henry S. Lee. M. IX, Boston :
  Dear Sir—Agreeably to your request, and in accordance with my own
feeliugs, I take the first opportunity to give you a brief history  of my
case, from its commencement, during its progress, and its termination.
  About twelve years ago I used to suffer with a dull pain across the
email of my back and  in my kidneys,  but nothing  serious was  appre-
hended.  This  continued until August, 1834, when I was taken sick, and
owing, as I supposed, to my taking  exercise  too soon, I had a relapse,
which brought me very low, after which  I never recovered my health.  In
the Spring of 1835, there was a tumor made its appearance at the  pit of
my stomach, about the size of a hen's egg, accompanied with sickness at
the stomach, and with sharp  pricking pains in the lower limbs.   I con-
sulted  several  physicians of  the highest standing in this county; some
were for cutting it out,  whilst others disapproved.  This tumor occupied
its station and size about one  year, when  it very suddenly disappeared,
and seemed  to affect my whole system, for I was  troubled with severe
pain  across the back and around the bowels, with increased numbness in
my limbs.   This pain was so severe and my strength  so prostrated I was
unable to dress or undress myself, lie down or get up without assistance,
and I was unable to leave my room in the morning without going double 
39
i ilh aiy hands on my knees.  At this time, one limb had become about
&/ree inches shorter than the other.  In this  condition I remained for
months.  In 1837, my physician considered my disorder to be the scrofu-
lous humor, and put me on a course of cicuta pills and iodine for four
months;  during this time  I frequently passed in my water a substance
like powdered brick.  In September, 1837,  a tumor made its appearance
on my side near the point of the hip bone, on the same side of the shorter
limb, which continued to grow for about six weeks, when it was opened,
and discharged a large quantity of thick matter, and it continued to leak
nearly twelve  months.  During this  period of time. I was better than
before, but soon after my side healed  I had more trouble with my water,
wliie.h came on by degrees ; and I then continued to suffer more or less
from  this time until March, 1841.  At times, the  pain was  almost
beyond endurance, sharp, cutting, grinding pains in  my kidneys, and  a
dead numbness down my thighs and lower  limbs, with spasms, heat, and
burning in the neck of the bladder, and along the urethra, accompanied
with a frequent suppression of,  and  constant  inclination to pass my
urine—sometimes every fifteen minutes, and with it bloody  stringy
mucus—some mornings  there would  be half  a pint of it settle to the
bottom of the vessel.
  In this condition, I applied to some of the  most skilful physicians in
the State, who did everything in their power to relieve me. to no effect;
and  although they  could  not help me, still by their kindness they are
endeared  to me through life.  Finding myself growing from  bad to
worse, I then applied to a Thomsonian  doctor, who is in high standing
in this county, but  he declined  to  have anything to do with my case.  I
then gave up all  hopes of a  cure, until  some time in the  month of
February last I  accidentally saw your circular, containing an  account
of the discovery of a medicine for the Stone and Gravel by Doct. S. H.
P. Lee, of New London, Conn., to  which was annexed the case of Jacob
G. Pool, and his cure by the use of Dr. Lee's Solvent.   On reading this
letter. I,  for the first time, thought that  the Gravel was my complaint,
and the sole cause of so much constitutional disturbance in my system ;
this conclusion was  so firmly fixed upon  my mind, by the description of
my case in Mr. Pool's letter, that  I immediately wrote to you. with the
st.tement that  his  letter was the  best description I could give of my
own case.
  On the l.r)th of February, 1841. I commenced the use of the Solvent,
following your directions, "in a very short time I began to feel a grinding
sort of pain in my kidneys, with sickness  in  the stomach, which continued
for a few days,  when the sickness left me.  I continued about the same,
as I supposed, until I had  taken up one bottle of the  Solvent, when I
wrote my second letter, and stated my case and the effects of the Solvent,
with a request for  you to send me  another bottle, if you thought  it
would help me.  You immediately sent me  another, and wrote me, '• that
by a steady adherence to your prescriptions,  the causes of irritation in
my system would be removed, aud  relief obtained," and encouraged me
topeis-vere.  As soon as I received the second bottle, I commenced upon
it again, although  I must confess with but very little faith, as I thought
I had already taken medicine enough to  kill or cure almost any man.  I
recommenced by taking a cathartic to remove my-eostiveness, and the
next morning  I  had one of my most severe paius and spasms, the most 
40
»evere that I have ever had ; no one present thought I could survive it.
It lasted me nearly two hours, when the pain left me, and I hope forever,
as I have never had one since.
   I have continued the Solvent from that time to the present, stopping
five or six days between each bottle, except  once, when I was without
the medicine six weeks.  While taking the second and third bottles, I
p*assed great quantities of thick, ropy matter, with fine, gravel-like sand,
of a dark ash color.  I have  been gaining my health steadily, though
slowly, from the time I commenced with the Solvent.  My pains are
mitigated aud almost entirely gone, my water clear, and less frequency
in passing, which was from ten to twenty times in a night, down to three,
two, and even one, now.   I have been for some time past able to work
moderately almost every day, and I expect in a very short time to bo
restored to perfect health.
                     Yours, with the greatest respect,
                                         Sylvester S. Learned.
  To Dr. Henry S- Lee, Gravel Infirmary, 18 Hayward Place, Boston.
                Letter from Solomon S. Palmer, Esq.
                                             New York, Dee. 24,1845.
   Dear Sir,—Being cured of the Gravel by your incomparable Lithon
 triptic, and feeling a deep sympathy  for those who may  be suffering
 under this most distressing disease, I consider it to be a duty no less due
 to suffering humanity than to your well-deserved fame, to communicate
 to the world briefly, my case.
   About  two  years ago, I was attacked with violent pains in my back,
 extending from my kidneys, through  the abdomen, to the  neck of the
 bladder, succeeded by great derangement of the urinary organs, and all
 the usual symptoms of Gravel, of the most aggravated character, such as
 suppressions, discolored and bloody urine, pains and numbness of my
 limbs, deposits of sand of all colors, &c, &c.  This state of things affected
 my constitution, and I lost flesh, and my spirits became depressed, my
 bowels costive, and my appetite bad.
   I began with your Lithontriptic  in  January, 1844, and continued it
 until  December  following, taking eight bottles.  My  disease was  so
 obstinate that  at times I became nearly discouraged, but believing that
 no other remedy would help me, I persevered, and all my disease gradually
 subsided, until I recovered perfectly,  and I am now enjoying first rate
health and spirits.
                           Yours respectfully,
                                        Solomon S.  Palmer,
                                                54 William Street
   To Dr. S. H. P. Lee, 78 Nassau Street.
              Case of Richard A. Elmer, Post Master,
                                      Ridgebury, Orange Co., N. Y., I
                                                April 15, 1847.    f
S. U. P. Lee, M. D., 36 Nassau Street, New York:
  Dear Sir,—Being cured of that most tormenting disease the Gravel
and Diseased Kidneys, by your invaluable  Lithontriptic, and feeling
great sympathy for the thousands of my fellow beings who are sufferin»
in like  manner, and who never heard of your name and fame (for I sco 
41
you don't compromise your  medical reputaton by newspaper advertise-
ments), still 1 think  it my duty  to address you, and, through you, to
inform suffering humanity that there  is (contrary to prevailing prejudices,
even among many of your  profession),  a sovereign  remedy  in your
Lithontriptic, which I verily believe will, in all cases, give relief" and
radically  cure where cure is possible.                                 ,
  As you well know, my own case was one of great severity.   My kidneys
seemed to be the suffering organs,  with the usual derangement of the
urinary.secretions.  My whole system suffered ; I  was rapidly running
down, after a seven  years'  endurance  of a complication  of  diseases,
(secondary, I think, from my kidney affection).  I had  been uDder the
treatment of seven different  physicians ; and after a faithful trial with
them all—to no benefit, save sometimes a palliative relief which was
more than counterbalanced by the ill effects of repeated blood-letting,
blisters, leeching, cupping, and last, not  least of my torments, setons,
lacerating the flesh, depriving me of the  power of locomotion and neces-
sary exercise—I  found myself in July, 1844, worse than ever.   While in
this situation, I had placed in my hands one of your treatises and reports
of cases ; and, as drowning persons catch at straws, I availed myself of
a bottle of your  Lithontriptic—(at that time it was with the greatest
difficulty  I could walk from Broadway to No. 36 John street, where your
office then  was)—and commenced taking the medicine immediately,  I
confess with faint hopes, for my skepticism was based upon  past experi'
ence.  After taking two or three bottles, with some improvement, I saw
the Rev. Mr. Wood, of Middletown, whom you had cured of Gravel some
two years before—and he advised me to persevere faithfully, and I did
so,  gradually improving until I had exhausted fourteen bottles, which
entirely restored my kidneys, and removed all those symptoms consequent
upon my  kidney affection ;  for which I feel most thankful to God and
your invaluable Lithontriptic.
  Now  sir, I have penned this letter, not  at your request—for you never
asked me for it—but in response to my  sympathy  for those  who are
Buffering  under  this direful malady, hoping you will invite  respectable
editors  to give it an insertion in their news columns,  and believing they
will do the public more benefit than  the"y can possibly do you in making
known the source where the malady  can be removed.
                        I am, yours, respectfully,
                                          Richard A. Elmer, P. M.
                 Copy of a Letter from James Stikeraan, Esq.
                      Port Richmond, Staten Jdand, N. Y., August 1,1848.
Doctor P. H. P. Lee, 73 Nassau Street, N. Y.
  Deak Sir—I feel it a duty I owe you and my fellow beings who are suffering witk
that terrible disease, the GRAVEL, to give you a statement of my case, hoping it may
be the means of giving relief to others, for I have no doubt thousands fall a victim to
it without knowing what their disease was.
  In the spring of 1851,1 was attacked with a severe pain  in the right kidney, lassi-
tude, bloating, faintness, loss of appetite, lowness of spirits, and shooting pains in tho
bladder, excruciating  pains  when passing  my urine; at times almost unendurable,
extending round my body and to the neck of the bladder, with frequent desire to pass
it—at times very slow,  and mixed with mucus and gravelly sediment, causing sharp and
pricking pains in the bladder and urethra, especially after taking cold.
  I continued in that state until the winter of 1S42-8, when my urine passed at night
without my being conscious of it.  I applied to three doctors, at different times who
irave me Balsam Copivi, Opium, Camphor and Tonics, from which I derived no  bene-
fit.  I then tried Harlem Oil  for six months but got no better.  I  then gave up all
hopes of ever getting well.  Mv bowels were so disordered that I could not void urine 
42
 with jut having a passag*.  I continued getting worse until 1S47, when I heard of one
 of your patients, on wnom I called, and from his statement I was induced to call on
 you; and it was you, sir, who told me for the first time, that I was troubled with the
 Gravel and Kidney disease.
  I began taking your Lithontriptic Pills the last of April, from which I soon got relief,
 and alter taking five bottles of your invaluable medicine, I have the pleasure of iuform-
 ing you that I am perfectly well, and now feel ten years younger than when you first
"aw  me.
  To you, sir, I offer my sincere thanks for your kind and gentlemanly treatment, and
 remain,                 Respectfully yours,                     Jambs Stikeman.
                                               New York, February  26, 1849.
Dr. S. II. P. Lee :
  For many years previous to taking your LithontripWc  I was troubled with dull pains
in the small of my back, at times severe pains in the bladder (particularly after taking
cold) and great difficulty in breathing.  My physicians had treated me for the asthma,
but I obtained no relief.  In 1846 I called on you, stated my case, and  was informed by
you that I was troubled with  Gravel.  I commenced  taking your Lithontriptic, and
after  continuing it about three  months,  entirely  recovered.   I  am now enjoying
excellent health.                   Respectfully  ycurs,
                                          W. 11. Tollman, 4 Thames St., Printer.
Extract of Letters from Charles Massey, Jr., Esq., Merchant, one of the firm of Ayre
  & Massey, No. 2S South Wharves, Philadelphia, after taking the Lithontriptic for
  stone in the bladder, which it disintegrated, alluded to at page 12, 4c.

                                                  Philadelphia, July 18,1844.
Esteemed Friend.
  Doct. S. H. P. Lee—Will you be good enough to send me a bottle of your Solvent,
for my own use, as I wish  to keep it by me, and I occasionally take a pill, and  drink
dandelion tea, although I have had no return of my complaint, and feel entirely well,
and have been so upwards of a year pant.  Enclosed is a five dollar note.  Please send
It by Adams' Express.                                                C. M. Jr.

                                                  Philadelphia, Jan. 19,1846.
  Esteemed Friend—I wish you to send me by Adams' Express, one bottle  of your
Lithontriptic, which I want for a friend of mine, for which I enclose a five dollar note
of the Commercial Bank of this city—direct as usual.
  J am perfectly well, and hope you enjoy good health.  With sincere regard,
                 I am yours, &c,                          Charles Massey, Jr.
Extract of a Letter from Francis Jame£ Robinson, Merchant, in Washington, Georgia,
      after having used the Lithontriptic some six months, dated April 29, 1S42.

  I can feel that the calculous formations in my bladder are gradually and perceptibly
less and  less—the heaviness formerly felt  is greatly lessened, and  I am enabled to
take easy exercise on horseback, without the consequences formerly felt; three years
since, a ride of one  mile would  cause a flow of bloody urine—now a ride of thirty
miles a day does not cause a drop to flow—your Lithontriptic  has performed wonders
with me, I assure you ;  without considering the good to my corporeal system,  it  has
awakened new feelings, raised new hopes, and almost produced a new being.
                       With feelings of gratitude, I remain yours, &c,
                                                      Francis James Robinsok.
Copy of a Letter from Doctor D.  N. Robinson, who purchases and  administers  the
                          Lithontriptic in his practice.

                                    Brownsville, Pennsylvania,  Sept. 15,1S46.
  Dear Sir—I have the pleasure to inform you, that both Mr. Hough  arid Mr. Palmer
consider themselves cured.
  I enclose  twenty dollars and request you  to send me as many bottles as you can
afford for  that amount, with pamphlets, &c.   Please write  me immediately after des-
paicliing the medicine, as there is a gentleman now taking it who will soon need a
further supply.  With best wishes for your health and happiness, I remain, dear sir,
                      Your obedient servant,             D. N. IIomnson, M. D. 
43
             Copy of a Letter from Judge Nbelb, of Alexandria, D. C
                                           Alexandria, D. C, March 3d, 1S47.
Doctor S. IT. P. Lee :                            .
  My Dear Sir—I enclose you three dollars, for a very poor and suffering fellow being,
for  a bottle of your Lithontriptic.   You will, I have  no doubt, disregard the  little
difference under circumstances of the case.  Please forward by Express.  The man is
named Carwood, a  poor mechanic of this city.  The doctors liere have done  theiW
utmost for him witlwut effect.
  I am happy to  be enabled to tell  you that  I  am  now in fine health.  To  Dr. Lee,
under God's mercy, I am indebted therefor.
                                  Ever your assured friend,          Chr. Nesle.
 A  ease  of  Gravel and Lithic Acid Diathesis, with Pulmonary Cough, Ilectic Fever,
   Night Sweats, and Muco Purulent Expectoration.  Given over as a hopeless case of
   Consumption.
   Mrs. Harrison, aged 88, residing at No. 55 Bedford Street, New York, in June, 1848,
 was first visited by Dr. S. H. P. Lee—she was confined  to  her  room and bed, sitting
 up in an easy chair, only about an hour daily ;  entirely emaciated, and so weak  as to
 be helped from bed to chair by her nurse; pulse from 100 to 12U—great night sweats—
» cough constant and severe—with pains in  the breast and back—chills every afternoon
 —appetite  declining—bowels costive—menstruation ceased  nine months  previous—
 youngest child ten years old. Her expectoration was copious, white and yellow, some-
 times ropy and  tenacious, and very offensive: on  further examination it was  found
 that she had been troubled for years with a train of kidney and urinary complaints,
 such as pains  in the back over the kidneys, extending to the  neck of the bladder, with
 frequent inclination  to pass her  urine, sometimes with difficulty, and soreness, and
 smarting—sometimes a little bloody—high colored, and on standing in the chamber
 would deposit a red and pink colored sediment, which adhered to the vessel—her urine
 acid—her  feet became  (Edematous—injections were resorted to to open the bowels,
 being too weak for cathartics;  her respiration short and  rather difficult, except in a
 recumbent position ; she had been attended by physicians of  high repute to no benefit,
 who gave up the case as hopeless.
    Doct. Lee, on receiving the  Pathognomonic symptoms of  her case, was of opinion
 that the primary cause of all originated in her kidneys, from a lithic acid diathesis of
 long standing, and that her pulmonary affections were secondary; that her only chance
 of  recovery was by treating the complaint as such, and rely  on the remaining consti-
 tional powers of her system to rally in her favor.  As drowning persons will catch at
 straws, she seemed to partake  of  a faint hope though skeptical, and wished to com-
 mence the Doctor's Lithontriptic at once.  She did so, and  after a week or ten days' us^
 of it, she seemed only to  hold her own, but she did not retrograde.  The opium she had
  been taking was reduced gradually to none,  after which, there was gradually perceived
  symptoms of  improvement—in six weeks there  was a  manifest abatement of  all  her
  symptoms, her cough and night sweats were  rapidly on the decline.  Her urine more
  [fee from  sediment and  mucus—pain less severe—micturition  less frequent—appetite
  improving—strength, both muscular and vascular, gaining—she now could walk about
  the room without assistance;  the  swelling of  feet abated.  On the 31st of August Dr.
  Lee visited her, and found her greatly improved in every respect.  She had now taken
  two entire bottles of his  Lithontriptic; her countenance began to give a healthy bloom
  —her appetite quite renovated, digestion  improved—cough less troublesome, expecto-
  ration  diminished—fever entirely subsided—pulse down to  SO;  she has gamed some
  flesh; her spirits buoyant and happy.
    Nov. 21.—Dr. Lee found her steadily and regularly convalescing, with a general ame-
  lioration of all her symptoms : gaining flesh, cough nearly well, expectoration reduced,
  appetite good, strength so improved as to walk around  a square, urine still turbid, ana
  considerable discharges of gravel; she has now taken  five bottles of Lithontriptic;
  still continues her extract of Taraxicum and Lithontriptic pill three times a day.
    April 11, W4— She is now so well as to ride to Doctor Lee's Infirmary Office ; con-
  stantly Improving, and has gained much  flesh; has a healthy countenance, and enjoys
  the pleasures of life, without annoyance from her old kidney complaints; continues the
  Lithontriptic daily.                           ,   . .,       ...  T..,___,,.:^,:„  ov,.
     April 21, 1S45.—Continues to improve under the daily use of the L.thontiipt.c  Nie
  has  now taken eleven bottles, and all  her complaints are nearly obliterated.  She still
  ha.  a weakness at the kidney region, but so slight as hardly  to be n»t«^r*e'",°"!j:
  lies  are regular; appetite good, countenance improved, thinks she  has gained upwaids
  of tl"rty pounds of flesh ; continues the Lithontriptic, because it regulates  her nervous
       m"d she always feel better when  she takes it.   She  is now so recoveredI as  to
  attend to her to household affairs, and walks and rides, and exercises with impunity. 
44
  Dec 4,1S47.—Continues well and enjoys excellent health ;  nothing has occurred in
this case worth noticing, except that she had a  fine healthy child, now six or eight
months old, and during parturition  and birth sickness was remarkably well.   She
continued  taking the Lithontrlpticduring the whole  time.
  Sept., 1648.—Continues well, and had much fatigue and anxiety, in consequence of a
long fit of sickness of her husband, Mr. H----, who still is confined to his house.
  The subject of the above case now resides at No. 36 Jones Street, New York.
A case of Stone in  the  Bladder, disintegrated by a long use of Dr. Lee's Lithontriptic,
  in a Lady of great respectability in Boston, communicated by Henry S. Lee, M. D.,
  member of the Massachusetts Medical Society.
                                                        Boston, April 21, 1S42.
  Dear Sir—Agreeably to your request, I send you a brief statement of Mrs. H---:—'a
case.
  Mrs. II----,  of Boston, aged 55 years, has been complaining for several years, mora
or less, of her right side and kidney.  Some three years ago, she passed a Renal Cal-
culus. During the summer of 1840, she complained of great uneasiness and pain in
the same kidney; at times  the paroxysms were very severe—in the latter part of the
month of October, of the same year, she had one of her paroxysms, and resorted to the
warm bath, and while in the bath she  felt distinctly something drop into her bladder;
ten days afterwards she passed a calculus of an oval shape, 7-3 of  an inch long, and
4-S of an inch in diameter, composed of the Triple Phosphates.  She was immediately1
afterwards sounded, and a calculus, about the size of a horse chestnut, was found in the
bladder—LWwtrity was then decided upon ; piepatory to this operation, she underwent
ueveral operations of sounding and injection, which produced so much irritation in the
bladder and in her general system, that the operation of Lithotrity was postponed, and the
Mineral Acids were administered.  Under this treatment  the disease became more
aggravated, the stomach very irritable, with a general prostration of the  whole system.
She had now been confined for five weeks to her room, and for ten days to her bed, when
the treatment was changed, and she was put upon Dr. Lee's Lithontriptic.  The irrita-
tion was immediately allayed, and large quantities of the Phosphates in the granular
and pulverulent form were eliminated from her.  In three or four days from the time
she commenced  on the Solvent she  was able  to  leave her room, her appetite was
restored, and in the course of two weeks all the symptoms of stone had ceased.  She
then submitted to Lithotrity (after a few preparatory operations of sounding) which was
abandoned after an unsuccessful attempt of three-quarters of an hour of searching the
bladder, leaving her with violent pains, inflammation, spasms in the bladder, and great
prostration of  the  whole system.  Under the use of  the Solvent and anodynes she
recovered again in the course of six weeks,  when she submitted again, and repeatedly
afterwards, to Lithotrity, from three to five minutes each time, with  the like success,
until, in the month of May last, they were partially successful  in seizing and clipping
off a few pieces of the stone.  But the subsequent attempts being unsuccessful, the ope-
ration was finally abandoned, and the patient  ordered to resume Dr.  Lee's Solvent.
During this period the patient was confined  nine months to  her  room, and underwent
many operations of sounding and attempts at Lithotrity.  Under  the  steady use of
the Solvent she has recovered her health and flesh  and since July last she has Lad no
symptoms of stone, enjoys her rides, walks, and attends to her domestic duties as well
as ever, and still continues in good health,  with the exception of an occasional feeling
of uneasiness in her right side, when she resorts to the occasional use of the Solvent for
relief, &c.                           Yours, &c,
                                      Henry S. Lee, M. D., No. 1 Franklin Street.
  To Dr. S. H.  P. Lee, 7S Nassau Street, New York.
         Case of Gravel and Kidney Disease mistaken for Spinal Affection.
  In 1S42. Col. R----, aged about 80, was attacked with severe pains in the back and
loins, attended with some fever and great prostration of strength—he was in a few
days confined to his house and room—an eminent physician was called in, who attended
him daily, and finding his complaint increasing in severity, called another distinguUhed
medical gentleman in consultation—the obstinacy of the disease and increasing suffer-
ings of the patient induced his physicians to  treat  the case  as a severe " Spinal
Affection."  He was mercurialized,  blistered, cupped, leeched, and last of all had a
seton put into his back, all of which prostrated him so that he could not move or leave
his bed, only by being lifted in  a  sheet from one bed to another.  His constitutional
powers, naturally good, seemed to be giving away to emaciation and functional derange-
ment of the secretory system;  his urine was highly albuminous, and of the color of
Port wine, with lithic deposits—frequent m'cturition,  attended with pain and distress
through the whole column of ureters and urethras. His medical  attendants, despair-
ing of  arresting the progress of his complaints, honorably consented to resign him to 
45
the care and treatment of Dr.  S. II. P. Lee, whose Diagnosis of the  case was, that
instead of any spinal disease,  its origin was in the kidneys, with probably a renal
calculi unpaged  in  the  pelvis of that organ; Dr.-Lee commenced his Lithontriptic
course immediately;  withdrew the seton, and  healed the wounds as soon  as possible.
At this period, he had  not been removed from his bed  for a week, and had watchen
every nijjjit.  His attentive and faithful nurse fed him like an infant; in a few days he
began to have less pains, and to manifest  symptoms  of convalescence—he continued
gradually to improve in every respect^he could now be  moved  from one  bed to
another; and at length to sit up, and with the arm of his nurse at length to walk across
the room—he now employed a pair of crutches, and thereby soon recovered his loco-
motive faculties.  His convalescence continued regularly, under the daily use, three
times a day, of the Lithontriptic, and  in about six or eight months was  well enough to
travel, and attend to business at his store.   He continues to enjoy excellent health at
this time, in  1848, and keeps the Lithontriptic, by him, and occasionally  takes it as
a preventive to a lithic diathesis.
  %W This case affords some very important reflections for medical men, who are so
unfortunate as to diagnose diseases upon mistaken grounds.
  Renal or Nephritic pains so  nearly resemble Lumbago and Rheumatic affections of
the back, that  other concurrent symptoms must be taken  into consideration before
the pathology of the disease is  in question, the urine should be chemically examined
at once with litmus, which if it reddens, and the urine is  of  a turbid or high  Port
wine color,  attended with frequent  micturition and sedimentary  albuminous depo-
sits, or any of these phenomena are manifest, it may be safely concluded that  tne dis-
ease is seated in the kidneys, and that there is a  calculus making  its way out of the
pelvis of one or both kidneys, and traversing the ureter to the bladder.
  The  symptoms, unler  these  circumstances, continue with  slight remissions and
exacerbations until relief is obtained by disintegration or such dilatation of the canal
as to permit its egress into the bjadder.   As we have not space here to dilate on this
subject, the reader is advised to peruse the  valuable and scientific work on Nephritic
and Urinary diseases by Robert Willis, M. D.,  London, of the Royal College of Physi-
cians; American  Edition, Philadelphia,  1839, chapter eight, page 150. Also, Sir B.
Brody, and Chrisiston, on the same subjects.
The case of Charles B. Morris, Esq., of North Carolina, a gentleman of respectability,
  and an officer in the Treasury Department, &c.,&c.

                                Smithville, Brunswick County, NorOi Carolina, I
                                                    October't&d, 1S43.          f
Doct. Saml. H. P. Lee :
  Dear Sir—I received your letter, dated Sept. 2Sth, 1S48, and also the medicine you
were kind enough to send me, to the care of R. W. Brown, Esq., saying you would like
to hear from me, after taking one bottle of your medicine, describing my case.
  When I commenced taking your Lithontriptic, my urine was very thick and muddy,
of an ash color, and had a bad smell; when it stood in the mug all night, one fourth of
it appeared to be a thick yellow slime, and  next above that looked like lime and water
stirred together, attended with a  continual desire to make water, and after thirty or
forty times trial through the  night, I would  not pass  more than a gill, accompanied
with all the pain that it was possible to live under; but in a day or two the inflamma-
tion at the  neck of the bladder would seem to subside a little, and then the urine would
pass from me as fast as it came  into the bladder; and thus I was afflicted either one
way or the other, for four or  five years.  I have had, in that time, some of our best
doctors, but they did not relieve me, or seem to know my case.   Their medicine was of
little or no  benefit to me ; s.»me of them tried the bougie, which only brought on a bleed-
ing and discharge of purulent matter; which has continued ever since, until I used
your medicine, and am now almost relieved  from pain in  making water; but  still  I
have to get up nine or ten times through the night, and have a disagreeable sensation,
when I make water, at the prostate gland; it throbs, and jumps, and beats; the doctors
here say it  is spasmodic ; this was never the case until after I used the bougies. My
bowels, at times, are very costive; I have great soreness across  my lower abdomen,
small of my  back,  and through  the  groins, my spirits much depressed,  and my
nervous system unhinged.  I think I continue to improve under your treatment, and
have a hope of  my recovery, and have now commenced  taking the third bottle. You
will please send me another package, like unto the first, of three bottles, to the care of
Mr. It. W.  Brown, at Wilmington, N. C, for which you have, inclosed, fifteen dollars.
Please ship it by one of the packets  that come to  .Mr. Brown, and  drop me a lin»
acknowledging the receipt of this, and much obligs    Your obedient servant, 
46
                                                 New York, April 21th, 1849.
  This day, being in New York, I called to see Doct. S. H. P. Lee, for the purpose of
Baying to him that his valuable Gravel and Kidney Lithontriptic Medicine has, I believe,
made a complete cure of me.  I can truly say, that I feel no symptom whatever of the
disease I labored under last year, and for which I beg that be will accept my grateful
thanks, as 1 am certain that, under Providence, he was the means of saving mv life.
                                                           Charles 1). Morris.
        Letters and Extracts of Letters sent to Doctor Lee for Publication.
The following Letter is from Rev. Horace Seaver, a Baptist Clergyman, and agent for
  the American and Foreign Bible Society.
                                                  Boston, Mass., May 80,1852.
To Doctor S. II. P. Lee, 78 Nassau Street, N. Y.
  Dear Sir—Having myself been, in years past, severely afflicted with the Gravel,
accompanied with  great derangement of the Urinary Secretions, and having taken
several bottles of your invaluable Litliontriptic, which, with God's blessing, has effected
an entire cure of the dreadful complaint, I feel a sympathy for suffering humanity, and
a desire to give my testimony to the efficacy of your medicine and to express my entire
confidence in its power to overcome and completely remove the disease, which, in my
case, had become very distressing.  It was  common for  me to pass away stones, Ac,
Ac, varying from the size of a mustard-seed to that of a beet-seed, besides sediment
resembling pounded  brick, attended with very severe  and excruciating pains.   I  am
now entirely relieved ; and have made  this communication—not only as due to you,
but for the good of any who  may be suffering from the effects of the same disease.
Should you think proper to publish this among the many testimonials  already in your
possession, you are at liberty to do so.                     Yours, truly,
                                                              Horace Seaver.
                                               Annapolis, Md., Nov. 17, 1851.
Doctors. H. P. Lee:
  Dear Sir—Please  send me three bottles more of your very valuable Lithontripic,
for it has nearly made a cure of me.  When I commenced  taking  it I was almost a
Bkeleton ; I now weigh  one hundred  and fifty pounds.   I have received so much benefit
from your medicine, that I am  determined to keep it up a long time.  The pain about
the region of the kidneys has nearly left  me.  1 have gained in flesh, strength, and
indeed every way, since I have been able to take the medicine in full doses.
                   Sincerely yours,                           Edward Dorset.
TERMS.
  Five dollars per bottle in advance, which will last about 80 days ; or $10 for a pack-
age of three bottles, which will last for a course of three months.
                       BRANCH INSTITUTE.

        There is  a Branch of this Institute, in Boston, under the charge of

                            HENRY S. LEE, M. D.
   Member of the Massachusetts Medical Society, and Boston Medical Association.


  N. B.—Doctor Henry S. Lee confines his practice in Boston, and all New England, to
Calculous and Chronic Diseases, such as Stone and Gravel in the Kidneys and Bladder;
Kidney  Disease, with its train  of secondary affections, such as Dropsy, Dyspepsia,
Chronic Rheumatism, Diseases and Hypertrophy of the Heart, Liver and Mesenteric
Glands, and general Infirmities of the Constitution;  also Gout, Strictures, and Diseases
of the Prostate Gland; and all Urinary Difficulties in males and female* ; Womb Diffi-
culties,  Fluor Albus,  or Whites, &c, Ac.  Persons in the country can consult him by
letter (post paid), or personally at his office in Boston.  His  references, In Boston, are
among the most distinguished citizens and Medical Practioners. 
47
REFERENCES.
DAVID AUSTIN, 24 William Street^-31 Union Place.
JOHN ACKEN, New Brunswick, N. J.
JAMES BROWN, Banker, 59 Wall Street.
BEWALL BENS'»M !»1 Sixth Street.
CHARLES BURilELL, Broker, 14 Wall Street.
DR. BAXTER, New London, Conn.
HOMER BOSTWICK, M. D.,504 Broadway.
R. VV. BROWN, Merchant, Wilmington, N. C.
J. BARBER, Merchant, Auburn, N. Y.
THOS. BULL, Jr., Secretary Manhattan Ins. Co., 51 Wall Street
J. BEAKLEY, M. D., New York House Hotel, Broadway.
JAMES BRACKET!'. Attorney-at-Law, Cherry Valley, N. Y.
SUMNER BULL, Saybrook, Connecticut.
WM. B CROSBY, 12 Rutgers Place.
OSCAR COLES, 91  West  Street, N  Y.
HENRY L. CHAMPLAIN, Essex, Conn.
HON. WM. B. CAMPBELL, M. C, Tennesseo.
JOHN P. COFFIN, 87 Maiden  Lane, N. Y.
ROGER  COIT, Cincinnati, Ohio.
JOSEPH R. CHANDLER, Editor U. S. Gazette.
I. CLARK, M. D., Manayunk, Philada.
AARON CLARK, Ex-Mayor of New York.
NICHOLAS DEVOROUX, Utica.
ALFRED  EDWARDS, Buffalo.
R. T. DORLAN, Troy.
JOSIAH DORMUS, Jamacia, L. I.
EDWARD C. DELEVAN, Albany.
PEl'ER EDES, 89 Front Street.
THEOPHS. F1TLER, Kensington, Philada.
C. 11. DE LA FIGANIERE, Minisiter Plenipotentiary fjr Portugal,
     Georgetown, D. C.
ROWFRT H. FOX, cor. Broad and Beaver Streets, N. Y
ALi'KKD FREEMAN, M.  D., 21S East Broadway.
WM. C. GIBBS, Ex-Governor, Newport, It. I.
JUDGE DAVENPORT, Hopkintou, Mass.
DOCTOR FORD, Hyannis, Mass.
WIN8LOW LEWIS, Boston, Mass.
JOHN C. GREEN, 72 South Street, N. Y.
WM. P. GREEN, Providence, It. I.
HON. WM. L. GOGGIN,  M. C, Virginia.
SYLVESTER GREEN, Herkimer.
AARON GRISWOLD, Clyde,  N. Y.
HON. SAMUEL D. HUBBARD, M. C, Middletown, Conn
JOHN HARRIS,  Fort Miller, Saratoga County.
J. F. HEINITSH, M. D., Lancaster, Pa.
WOLCOTT HUNTINGTON, Norwich, Conn.
JOSEPH HUDSON, IS Warren  Street.
IRAD HAWLEY, 21 Rutgers Place.
VINCENT HOLCOMBE, M. D.,  West Granville, Mass.
EDWARD INGRAHAM, Saybrook, Conn.
FRANCIS HART, 117 Liberty Street.
JOHN S. LOTT, Jamacia, L. I.
LEWIS G. MORRIS, Fordham, N.  Y.
THOS. MARFAN, Astor House,
WM. V. MANY, Albany.
THOS. MINER, M. D„ Hartford,Conn.
SAMUEL MeCLELLAN, M. D.,  Nassau, Rensselaer Co., N. Y.
A. M. MERCHANT, Sec. N. Y. F. Ins. Co., 22  Pike Street, N. T.
CHARLES MASSEV, 28 South Wharves, Philada.
B. F. NOURSE, Bangor, Maine, Collector, Apalachicola.
JUDGE CHARLES NEAL, Alexandria, D. C.
ISAAC OTIS, New York City, Prest. Bank. 
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