L4-Slr /£43 ft^^^ik£;M:::^'1::":^^d:^.::«;-v SFNi&fe*;; f'#^ I ':i'-: "ft ■ *" ■■■•:,* ■"' * :■■■■ [Wfif^'ljfer!:r-t'¥jjl-»■ ■ - v-1" .••'te. ^j^feeri -,-;r.i-!.! !,titJ.ji^;^^a?3K:Vr." •;,.- :,.■km-.■.l^.y-y-V.-- ■ _'*•£• ,-jj-^- REMARKS STONE AND GRAVEL KIDNEYS AND BLADDER, WITH AN ACCOUNT OF THE \ 3 G 6 >y* ^ J*a v DISCOVERY OF A SOLVENT REMEDY, NOW USED WITH UNIVERSAL SUCCESS, AND COMMONLY KNOWN AS Bo 5L31IM ©3BAYHIL SPJEOH BY SAMUEL H. P.1EE, M.D. Member of the Medical Society of Connecticut. THIRD E DITION.... COPY RIGHT 1843. HT SECURED ACCORDING 1 TO LAW —'V^"-:** l- .^O^ WJ U2\r If 43 ^*m> TO THE PUBLIC. My name having been before the public for a number of years, as Author and sole preparer of the " New-Lon- don Bilious Pills, I trust an apology need not be made for its re-appearance with another offspring from my Medical-/SttM^io, when they are assured that I am forcibly pressed to do so by the repeated requests and solicitations of patients who have been cured of this distressing ma- lady, by the use of my Solvent Remedy, thereby evincing in them an honorable sympathy for the sufferings of others. The only objection, so long entertained, of giving to my medicine a public character is, the cupidity with which unprincipled panders seize upon every public medicine of repute, and with a base and fraudulent counterfeit, disap- point the public expectations, to the great injury of both the afflicted and the proprietor. But the public good de- mands this sacrifice, and I yield my scruples, believing that by affixing my written signature to each package, tho afflicted will be secured in the benefits of my genuine article. Some twenty years ago, I prepared a compound vege- table Solvent, for a patient most severely afflicted with the Gravel and Stone in the kidneys and bladder, which effec- tually and speedily performed a radical cure. Such was the powerful operation of its solvent and cleansing pro- perties upon the Renal organs, giving ease and comfort in the most distressing paroxysms, and finding the same hap- py effects in every case, and in numerous other cases, I adopted it in my nomenclature of practice, for all calcu- lous afflictions of the kidneys, bladder and gall ducts, with equal and satisfactory success. From that period to the present time, I am very frequen^lv,.called upon for this medicine, from all parts of the/wo^p,#where Yankee enter- prize have invited those once cured, who communicated the facts to their suffering neighbors. This Medicine is now before the public, based on the fairest prospect of doing much good to suffering huma- 4 nity. Its distinguished merits, over every Lithontriptic I have ever known, warrants and sustains my firm belief in its future celebrity—a celebrity not dependent on puff- ing advertisements, but in the smiles of happy mortals, proclaiming to the world a sovereign remedy. No one, of either sex, age, or constitution, however severely afflicted, or however long, need to despair of a cure—or at least manifest relief. A short trial will convince the most skep- tical of its powerful influence, and insure a perseverance until a radical cure is effected. To Medical Practitioners, and more particularly to those who have for many years found my Bilious Pills a conve- nient and effectual cathartic, in their daily practice, I ven- ture to presume upon their disinterested philanthropy, and invite their attention to the trial of my Solvent Lithon- triptic, and can assure them that their success Avill exceed their highest expectations. That the public may not hastily conclude that this dis- covery is a catchpenny affair, like too many of modern an- nouncement—and that I have not held my name and me- dical reputation so fragile as to patronize every new born panacea, I beg leave to submit to the reader the following testimonials of my medical character in early life, trusting that in my more advanced experience, I have not retro- graded in Medical knowledge and usefulness. " VOTES OF THE CONNECTICUT MEDICAL SOCIETY." At a meeting of the Fellows of the Connecticut Medical Convention, October, 1794, Voted, That the thanks of this Society be given to Doct. Samuel H. P. Lee, of New-London, for his ingenious an- swer to their second prize question, upon Autumnal Bilious Fevers. At a meeting of the Fellows, &c, in May, 1797, Resolved, That the thanks of this Society be given to Samuel H. P. Lee, New-London, for his answer to their prize question—" What is the best method of preventing Quincy, (Cynanchv^fynsillaris of Dr. Cullen,) after the inflammatory state is fmly formed, from terminating in mo- turation and discharge ?" 5 A FEW OBSERVATIONS ON THE HISTORY AND PROGRESS OF THE DISEASE. Ever since the days of Hippocrates, medical men have been anxiously looking for a solvent for the Gravel and Stone in the kidneys and bladder; the ancients investi- gated the subject with great ardor—tried many experi- ments with such articles as were known, to dissolve Cal- culi out of the body, but failing to reach such substances through the sanguiferous system, gave up the pursuit, and rested their hopes upon the future developements of medi- cal science, fully persuaded that so formidable a disease must have an antagonist remedy, with specific powers to dislodge the system of such extraneous particles. The Greek physicians made some progress in prevent- ing, but none in curing the disease ; they very properly conceived the idea that a vitiated and deranged digestion laid the foundation for impurities in the blood, which in passing through the emulgent secretions, formed a viscid mucus, combining with the uric or ammoniated salts, aa they conceived, thereby generating earthy substances, and lodging in the kidneys, and from their irritating surfaces forcing their passage through the ureters in the bladder, there to accumulate into stone, or perchance pass off by urine. During the early ages of Christianity, medical men did not relax in their researches, and laid the foundation of a more rational system of Pathology, by the adoption of articles taken into the stomach, having a direct action on the kidneys and emulgent secretory organs. Galen, Para- celsus, Helment, and others, up to the time of Booerhave exercised all their physiological powers to this object, but their success was evanescent and unsatisfactory, and seemed to yield to the induction of operative surgery, among the improvements of which, Lithotomy took the foremost rank, as a substitute for Lithontriptics. From the days of Booer- have to the present time, the science of medicine has un- dergone great and important changes, by the revolutions produced from chemical developments, and raised the ex- pectations of many, that as the ancient doctrines of earth, air, and water, long supposed to be primary elements, has become merged in the discovery of their heterogemous combination, a prejudice in favor of chemical remedies was introduced, which by dissolving calculous concretions 6 out of the body, were confidently expected to pass the bar- riers of digestion, instead of entering the circulation, and the secretory vessels of the kidneys unchanged. The Pa- thology of the disease, and the phenomena of urinary calculi examined by the new chemical tests, opened the flood gates of genius, and the most fanciful theories, foud- ed on the doctrines of acids and alkilis prevailed. Each sect had their day, and the boldness with which they administered those agents, beyond the incompatibility of direct medicinal influence, brought their practice into dis- repute, and most of their medicines being of a caustic and irritating nature, the delicate and exquisitely sensible mem- branes of the bladder thereby suffered nearly as much from morbid inflammation produced, as from the mecha- nical action of the angular points of gravel. Still the experiments went on, and the hopes and wishes of the most zealous, confidently expected that some lucky hit or accident (as most of the useful discoveries in combined medication are obtained) a solvent detergent adapted to the case would be produced, which genius and chemical philo- sophy had failed to accomplish. An eminent French writer {Paris) says, " The urine may be considered as one of the most heterogenious of ani- mal fluids;" and this remark is verified by the fact, that from the elaborate analysis of Berzelius, he found this fluid holding in solution thirteen different substances ; hence the impracticability that a single agent could dissolve those extraneous substances in the body ; combinations, multi- form and antagonistical in their vital action, were resorted to with no better success, and palliative remedies with the quieting powers of opium, were the only leading indica- tions of the schools of medicine for the last century in this disease." These remarks lead me to announce to those suffering under this malady, that I have made a Pharmaceutical dis- covery, in the combination of vegetable and chemical agents, which, when administered, dissolves calculous concretions, and ejects them from the kidneys and bladder in the urine. This important and long looked for desideratum is now fully demonstrated, by a course of practice for many years, with unexampled success. Among the numerous cases which have been cured by this remedy, a number of the certificates have been drawn up by the sufferers them- 7 selves, and voluntarily communicated for the benefit of the afflicted, supported by facts which cannot be controverted. Medical men may possibly doubt the existence of such a discovery and exhaust their argumentative powers, un- der the banners of modern chemistry, and arrive at con- clusions apparently satisfactory. But it is ever to be remembered, that theory is one thing, and facts resulting from well tried experience, is another. I trust that no one who claims to sympathize with his suffering patients, will yield to professional prejudices until he has tested the powers of my compound. To such whose liberality is open to conviction, I tender my services and medicine for their personal observation. The success of this remedy authorizes and requires my exclusive attention to this dis- ease. The afflicted at a distance may consult me by let- ter, (postage paid) describing their case from its com- mencement, giving the leading symptoms which charac- terise the disease, the remedies used, state of the consti- tution and condition of general health, &c, and imme- diate attention will be given to all such applications if accompanied with a fee of Five Dollars, which will pro- cure medicine enough to cure a case of moderate severity. Resident patients will be charged according to the severity of the disease, and ability to pay, subject however to their voluntary approval. The poor, on recommendation in writing by the clergy or civil authority, Gratis. Saml. H. P. Lee, M. C. M. S. ON THE STONE AND GRAVEL, OR LITHIASIS. Particles of stone, or earthy, gravelly concretions, are known to float in the circulating fluids of the human body, and to form into concrete masses, in many of the secre- tory organs, more especially in those applicable to the secretion of Urine. The causes which produce the deposition of these par- ticles in the kidnies, bladder, gall ducts, &c, &c, are variously accounted for by medical writers ; but as all classes of people, ages and sexes, whether living in luxury and plenty, or in the humble walks of poverty, are liable to the disease, it would be difficult to point out any parti- cular regimen of diet, or habits of life conducive to its appearance. It is sufficient that calculous diseases exist, 8 and much more frequently than is generally supposed; my present purpose is merely to describe its character, and present the remedy. SYMPTOMS. The gravel in the kidneys and bladder, is attended with a fixed pain in the loins, numbness of the thighs, nausea, vomiting, and not unfrequently with a slight suppression of urine. As the gravel removes from the kidneys down into the ureters and bladder, it sometimes produces such acute pains as to create faintings and convulsions. The patient, at times, cannot bear any kind of rough motion or great exercise, without enduring great torture, a dis- charge of bloody urine, and some degree of temporary suppression—pain in the neck of the bladder, tenesmus, or griping and itching of the Sphincter Ani—cold chills, uneasy desponding feelings, inaction and lassitude of the whole body, discharges of bloody urine, depositing a se- diment of gravelly matter, sometimes red, at others of an ash color, with a glairy mucus covered with Aliments or stringy substances. These symptoms are generally aggravated by exercise, particularly by riding on horseback ; and from a long continuance of pain, and from that want of rest which frequent returns of the paroxysms are sure to induce, the patient's state of health by degrees becomes much im- paired, and unless some effectual means are now employed for removing the cause, it commonly happens tnat his misery is only terminated by death, or a life spent in mi- sery and distress. DIRECTIONS. If a patient, when about to commence the use of this Solvent Medicine, happens to have a constipation of the bowels, or is very costive, he would do well to take a ca- thartic of some opening medicine, such as Castor Oil, or any purge he is familiar with, to prepare the lacteals for an active absorption. His diet and daily drinks need not be changed or altered, except in avoiding the use of fermented liquors, and wines abounding with tartar, and all acids. If in the daily habit of using much liquid drinks, he will do well to substitute those for a decoction of the dandelion which may be made agreeable by sweetening, to the ex- tent of from a pint to a quart in a day, to aid the medi- 9 cine in its effects on the absorbent and secretory organs, especially those leading directly from the stomach to the kidneys. If the dandelion cannot conveniently be ob- tained, (it can always be obtained at the Druggists from the Shakers) then soft water, either rain or spring, or any water free from mineral impregnation, maybe used. This medicine will not interfere with any out-door exposure, such as easy travelling, or gentle, regular exercise. He should observe the same rules of diet and exercise that a temperate habit would enjoin upon a healthy person. Per- sons engaged in any active employment on land or water, may use the medicine without any ill effects. Its salu- tary results are soon perceived by a passive amelioration of all his distressing symptoms and a freedom of the se- cretory evacuations, and should be persevered in until the complaint enthely disappears, and the urine has a natural and healthy appearance. To dissolve the calculi, or gall stones in the biliary ducts, known to exist by the violent paroxisms of sharp, cutting, pungent pains, at the pit of the stomach, extending through the region of the liver, with vomitings accompanied with white or light colored stools, the medicine should be continued two or three months, omitting five or six days at intervals, once in three weeks. During such intervals, a dose of two or three of my genuine Bilious Pills (to be genuine, the enve- lope upon each box must have the same " written signa- ture'''' that is attached to this icork) would aid the Solvent in its action upon the gall stones by stimulating the ducts, and thereby facilitate their passage into the duodenum, relieving the patient immediately. To prevent a recur- rence of the gall stones, the Solvent should be continued, about one pill per day, for one or two months, in bad cases. Dose.—Take a pill of this compound [per sample] morning and evening, upon an empty stomach, for three or four days ; then take three times a day, morning noon and night. Thus continue until a cure is effected, which will generally be accomplished in three or four weeks, in ordinary cases; but when the disease is of long standing, or a large stone in the bladder or kidneys is to be dis- solved it will take from five to twelve months. To make the cure permanent, and to restore the fluids and secre- tory organs to a healthy sound state, it would be advisable 10 to continue the medicine, reduced in quantity to a pill per day, and every other day, for weeks, or months, accord- ing to the previous violence of the disease. This medi- cine is also good in a variety of other complaints, as sour eructations, or sour stomach, gout, rheumatism of the joints, dyspepsia, infantile diseases, such as cholera infan- tum, heat and excoriation of urine, strictures in the uri- nary passages, &c, &c. Children under ten years of age, should take half the quantity, or half sized pills, in the same divisions of time. RULES TO BE OBSERVED WHILE TAKING DR. LEe's MEDI- CINES FOR THE GRAVEL AND STONE. 1st. All other medicine of an alterative character, of any description whatever, commonly used or recommended for the disease, is strictly prohibited ; this prohibition how- ever, is not meant to include Anti-spasmodics, or Cathar- tics, if from the violence of pain, or nervous irritability, or constipation of the bowels, remedies to remove either, such as Opium, Morphine, or any customary active Ca- thartics to open the bowels, are indicated ; when purga- tives are necessary, the gravel medicine should be omitted during the operation, and resumed as soon as the bowels are opened. 2d. All acids, such as Vinegar, Pickles, Cider, sour Wines, sour Bread, sour Fruits, Lemon Juice, sour Oran- ges, Apples, Lemonade, &c, are to be strictly avoided, as they will change the character of the medicine in the stomach, and render its effects inoperative. 3d. The patient's diet and regimen may be continued as usual with the exception of acids as above. If accus- tomed to Gin, Brandy, Madeira, Sherry or Port Wines, they may be continued moderately, if desired. All kinds of food that is easy of digestion, either animal or vegeta- ble, should be preferred ; moderate exercise and atmos- pheric exposure, as usual, does not interfere with the ac- tion of the Solvent in the system. 4th. The medicine should be taken from half an hour to an hour previous to eating any food. 5th. A patient perseverance in the use of the medicine, as long as any symptoms of the disease exist, is recom- mended, the use of which is always sure to improve the general health, appetite and digestion. 6th. Honey may be used freely in the tea if desired. 11 TESTIMONIALS. The following certificates, among a great number of the same tenor, were sent to me by the writers, with a desire that they be made public for the benefit of mankind: New-York, October, 34,1829. it is with great pleasure, and a duty I owe to the public welfare, that I hereby acknowledge the great utility of Doct. S. H. P. Lee's celebrated Pills for the cure of the Stone and Gravel in the kidneys and bladder. I have used them for some length of time m my practice, and am happy to say, have uniformly found them successful. I may add also, the testimony of many of our first Physicians in this city, who have used them in numerous instances, and speak of them in the highest terms." "With these facts to support their beneficial effects, I do with the utmost confi- dence recommend them to all those who are afflicted with these distressing com- plaints. (Signed) T. JONES, M. D." " New-York City, October 20,1829. " I am fully satisfied from much experience in my practice, that Dr. S. H.P. Lee'9 compound Pills, for the Gravel and Stone, with its concomitant Nephritic symptoms, are an invaluable medicine, and infallible in almost every case, by eradicating the Stone or Gravel from the bladder, and so correcting the blood as to remove the ten- dency of the kidneys and Renal secretions to deposit calculi in the bladder, the cause of Stone ; thereby avoiding the severe operation of Lithotamy, or cutting into the bladder. I have used the medicine freely and it has invariably removed the complaints, affording ease and comfort to the patient. The article is worthy the attention of the public, particularly those who labor under thdse destressing complaints, and, in my opinion, is the nearest to a perfect remedy of any composi- tion to be found in any Materia Medica or medical writer. JASPER C. FOSTER, Surgeon." The writers of the following are grave honest men, of the first standing for moral and religious integrity ; their object is the welfare of the afflicted. Those now living in 1839, have informed me that they are entirely free from the complaint. Waterford, Conn. June 5, 1830. " To whom it may concern. This is to certify, that I have been troubled with that distressing complaint, the Gravel, for twelve years—have had many poor turns, so that I had to lay by all business. I was often attacked with sharp, cutting, grinding pains in the kidneys, back and thighs, which are indescribable—after some hours, would seem to abate for a time and then return, discharging thick bloody urine, with redish sediment, &c. I had almost dispaired of getting cured, especially when I had the most excruciating pains imaginable—I tried the Harlaem Oil, and many other remedies. I consulted physicians, some of whom informed me there was no cure for it—I took their medicines to no effect. At last I heard of a composition of Doct. S. H. P. Lee of New London, formed for this disease, which I took for three or four weeks, and at the same time drank freely of dandelion tea as a common drink; as it was inconvenient to get the tea at all times, 1 carried the dandelion in my pocket and chewed it. I got entirely well of the gravel in a few months—taking the compound, the parts healed, and I have had no return of it since. I therefore certifv this for the benefit of others afflicted with the same complaint. OLIVER MAXSON. Oct. 1839 Mr. Maxson still enjoys perfect health, and may be inquired of at his farm in Waterford. Waterfoed, Conn. April 30,1829. " This may certify, that 1 was troubled with the Gravel upwards of seven years, for which time I was unable to do much business, and had not much hopes of ever being able to do anymore. I applied to several physicians in New-York, Baltimore, and many other places, of the first standing for medical skill, but received no bene- fit from their prescriptions. I happened, by chance, to call on Doet. S. H. P. Lee, of Ni-w-London, Connecticut, and after taking his Pills, prepared for that disease, three 12 weeks, by taking three pills a day, viz : one pill morning, noon and night, I was entirely cured of that grievous complaint, and I have not been troubled with it since. This was about ten years ago, and I have known a number of persons, who have informed me that the pills have cured them. Having some of the medicine left I gave the same to a Mr. Champlin of Lebanon, Ct. who informed me that it cured him and his wife also, and, that if requested, he would certify to the same for the public good. ISAAC f£D£ER^- The writer of the above informs me now, in 1843, that he remains entirely well. He may be inquired of at 160 Duane street, New York. Waterford, Ct., February 3, 1831. Doct. S. H. P. Lee—Sir—About three years ago my son, Win. R. Beebe, came to my house from the State of Ohio. He informed me that he had been troubled with the Gravel for many years, and had employed all the Doctors in that part of the country, but could obtain no relief, and said as he could not labor, he came on to see his relatives once more, not expecting to live long in that situation. He took jour gravel medicine for about two weeks: it brought away a large stone and much gravel from him, and on continuing the medicine, he passed another ; he got entirely well and returned home. I have received letters from him since frequently; he informs me that he has not been troubled with the complaint since. I found that I was trou- bled with that complaint lately, without knowing what was the matter with me. I took your medicine about the same time he did, and it cured me entirely. I can 6afely recommend them to others, hoping that this valuable medicine may have a general circulation, for the good of mankind. I remain your friend, PAUL BEEBE. Waterford, Conn. 13th Oct. 1829. I hereby certify that I have for a short time, made use of Doct. S. H. P. Lee's Pills, prepared for the cure of the Gravel, and have obtained help by the use of the same, having been troubled with the complaint for fifty years. I am now eighty-eight years old. JEREMIAH BROWN. Waterford, Conn. July 10,1829. This may certify, that I have been troubled with the Gravel from infancy, and by taking some of Dr. Lee's Pills prepared for that purpose, have got well. POLLY DUNBAR, New-London, Ct. Oct. 20, 1818. " I hereby certify, that for many years I was afflicted with the stone and gravel. I had severe pains in my back, hips and loins. I passed a great quantity of a redish, brick colored sand, and sometimes little stones of a yellow cast, and very rough. Sometimes I was much troubled in passing my urine, and then it would be bloody and mixed with white glary matter : sometimes a sickness at my stomach, and a loss of appetite would follow the excessive pain, and when I labored hard all day at caulking under a ship's bottom, I was generally worse at night. I suffered severely for many years, although I took medicines from several doctors, which sometimes would relieve me for a few hours, and then return again as bad as ever. I gave up ever being cured, until a friend told me to apply to Doct. S. H. P. Lee, who he said had cured him of the same complaint. I did so, and took his Gravel Pills about four or five weeks, and was entirely cured. While Iwas taking the Gravel Pills, I passed several stones, one of which measured three-fourths of an inch in length. I have had no return of the disease for several years, and am as well as I ever was in my life- NICHOLAS DARROW. The following Letters are published by the special re- quest of the writers :— ^ „ „ East-Haddam, Conn. January 23d, 1840. Doctor S. H. P. Lee : Dear Sir,—For several years past, I have been subject to frequent attacks of the jvEj' lnlhe kidnevs and bladder, so severe at times, as to confine me to my house and bed, and my general health has been very much impaired thereby. The attacks would come on with a severe pain in the small of my back, across' my loins with numbness in my lower limbs, accompanied with cold chills, and great irritability of the stomach, and in the neck of the bladder, with a constant inclination to void 13 urine, attended frequently, with a disability to do so, and which deposited a red gravelly sediment, &c. Having taken the prescriptions given me by different Physi- cians, and deriving only temporary relief, I began to despair of ever getting entirely cured until recently ; having a severe attack last summer, I applied to your son at Leesville, to prescribe something to relieve me. He informed me, that when he was in Practice, he had entirely removed this complaint in several instances, with your compound Gravel Specific. He obtained some from you for me, and I contin- ued to take it according to your directions for three or four weeks, when all my dis- tressing symptoms were entirely removed, and my general health began immediately to improve, and it is now sir, more than six months, and I have had no return of the disease, and my health generally, has been better this winter, than I have known it for several years, which I impute entirely to the effects of your medicine. Having recently read your treatise, on the Gravel, it gave me pleasure to find that you had taken a course, by which the public are to have the benefit of your medicine, and as I have had an opportunity of testing its curative effects, in my own case, 1 shall most cheerfully recommend it to all those who are troubled with this afflicting dis- ease. I am yours, &c. HYRAM CHACE. New-London, February 28,1840. DR. LEE—Sir,—I have been afflicted with the gravel from my infancy ; when a child, I can remember having often a hot Flat-iron applied to my back, and other remedies for pains ; at seventeen years of age, I was severely troubled with sharp pains in the Kidnies, and across my back, and down my thighs, with great heat and numbness : I discharged great quantities of a reddish Gravel and bloody urine, at- tended with great pain and heat at the neck of the bladder ; my Kidnies became swelled, dropsical symptoms threatened ine, my general health became bad, I had frequent suppressions of urine, and was obliged to resort to a Catheter,