NATIONAL LIBRARY OF MEDICINE NLM DD1D3S7D E % yy^-r'Q'C Surgeon General's Office £1 tjs * #fc cTWJ^ ##-, >•-■£,■>■, »..-/aatro t PRESENTED BY \l &r^- rri^-err-^ JgOOOOC ■ J U D OD'LC i+J -.C u j< NLM001035702 SIMILIA SIMILIBUS CURANTUR? ADDRESSED TO THE MEDICAL PROFESSION, BY CHARLES S. MACK, M. D. " It is better to debate a question without settling it, than to settle it without debate."—Joubert. BOSTON AND PROVIDENCE OTIS CLAPP & SON. 1888. V/BK MI53s /--'A, /v/c? -7//7 , >«-* s_ Copyright, 1888. CHARLES S. MACK, M. D. SIMILIA SIMILIBUS CURANTUR? I. I see nothing to accept or offer as positive, practical proof that similars cure; on the other hand I see nothing to accept or offer as positive, practical proof that they do not. Until one has seen such proof pro or con, he is obliged to hold in abeyance the question of fact, whether similars cure. A question of opinion, however, which he must practically answer each time he treats a patient is, Is it worth while in this case to try to cure with a similar? I hope that in the following pages some light will be thrown upon this question of opinion. When one states publicly what he thinks of homoeopathy it is important, to himself at least, that in doing so he be very accurate. I shall therefore offer no apology for stating here what is my personal position in this matter. My experience with homoeopathy has been very limited. A question which cannot be answered now is whether I shall ever be able to say that I know I have seen cures effected through similars. At present I cannot say this, and I suspect that the theoretical argument in favor of similia is 4 Similia Similibus Curantur ? stronger than any practical evidence of a positive nature in individual cases which is obtainable today that similars cure. I say of a positive nature: the difficulty is, of course, that of distinguishing between recovery or improvement which has occurred independent of any influence from the medi- cine used, and recovery or improvement in effecting which the medicine has been instrumental. This difficulty obtains whether the treatment whose usefulness we would estimate has been homoeopathic or non-homceopathic. I say, too, in individual cases: the question as to coincidence being less of an embarrassment in considering a number of cases than in considering a single one, absolutely accurate statistics of a large number of cases might afford valuable practical evidence for or against the efficiency1 of a homoeopathic drug to cure, but the difficulty of attaching proper weight to statistical evidence in medical questions must be recognized. In view of such difficulties one need feel no hesitation in ex- pressing an opinion while he is not prepared to adduce facts for the support of it. I think no practice is more useful 1 The question as to how much of a medicine should be given is aside from the subject of this paper. As a matter of fact, however, the attempt to cure with similars is usually made with small doses. If one is disposed to look upon the harmlessness of these doses as a practical argument in favor of homoeopathy, let him, nevertheless, bear in mind that the harmlessness of a given treatment may have absolutely nothing to do with the question as to its efficiency. Similia Similibus Curantur? 5 today than one which has regard to similia as the law of cure, but which is ready in the treatment of any case to do what may in that case promise more of usefulness than does an attempt to cure; and that no other practice offers to medical science such a prospect of future progress as does that which has regard to similia as the law of cure. Each of the words homoeopathy and cure has attaching to it various meanings, and I wish to specify in what sense the words are used in this paper. The principle expressed in the formula similia similibus curantur is what the word homoeopathy etymologically implies, and that principle is the subject of discussion in this paper. We shall use the word homoeopathy as simply implying a recognition of that principle as law. We shall use the word cure as synony- mous with the removal of disease by means which do not affect primarily a cause attacking man from without, but which do so modify the vital processes in a patient as to enable him to resist morbific influences. Cure thus de- fined does not necessarily involve the idea that a disease whose natural course is of definite duration shall, as a result of curative treatment, have its duration shortened. I am aware that there are those who, after long experience and very careful study, have come to believe that no such thing is possible as curative medicine. I think that such a conclusion is premature, if the theory of homoeopathy is correct. 6 Similia Similibus Curantur? In defining Poison Webster says, "The ancient Greeks " employed the same word both for a medicine and a poison ;" he says too, "According to the popular notion, those articles " only are poisonous, which are capable of producing morbid, " noxious, or dangerous effects, in comparatively small quanti- "ties; but there is no just foundation for such a distinction." Now, similia implies that any curative medicine is a poison — that if taken in sufficient quantity in health, it will produce morbid effects. The difficulty of inducing with drugs effects which resem- ble in any considerable degree those of many diseases with which we have to deal is not to be blinked, but I think that a difficulty equally great, and of much the same nature, must be met by any practice which attempts to cure other- wise than empirically. This point will be touched upon again : let us for the present observe simply that the theory of homoeopathy finds no obstacle here; the difficulty is a practical one, and while it may embarrass one in the treat- ment of some cases, perhaps very many cases, it need not, I think, deter him from regarding similia as law. Some cases may be incurable for aught similia says. There is no inconsistency in accepting the belief that in poisons we have curative medicines, and at the same time admitting that medicines may be useful which are not curative. If in anaemia the blood has not its normal amount of iron, and that deficiency can be supplied by Similia Similibus Curantur? 7 administering iron, well and good; but, though that iron is called medicine and not food, administering it is certainly a very different matter from prescribing a poison which we hope will by modifying the processes of the vital powers be an instrument of cure.2 Chemically acting upon the con- tents of the alimentary canal, or, by means concerning which similia says nothing, removing parasites which have been introduced into that canal from the outside world is no more prohibited by similia than is mechanically remov- ing from the surface of the body parasites or dust which have adhered to it in its contact with its surroundings. Under the same category come the cleansing of wounds and the killing of germs which have been introduced into them from without. Similia does not prohibit stimulating 2 If the view supported by Dr. Richard Hughes is correct, the action of a medicine useful only in supplying to the system an element which is present in health and absent in disease does not fall under any law distinct from the laws of dieteties. [See his Manual of Pharmacodynamics, Fourth Edition, page 339.] Drugs useful in some such way as this may be indefinitely many,—preparations of lime or phosphorus may be among them: quinine may be one. [See "A contribution toward our knowledge of the pathological changes in the fluorescence of the tissues," by Edward Rhoads, M. D., and Wm. Pepper, M. D., in the Pennsylvania Hospital Reports, Vol. 1, (1868) in which paper are recorded some observations upon effects of quinine sulphate.] If there is a curative medicine for such cases, it will so modify the processes of the vital powers that the deficiency, which is an effect of abnormal processes, will not persist. 8 Similia Similibus Curantur? a patient through the duration of an acute disease. It does not prohibit the use of palliatives : it says nothing about them. It does not say that morphine may not be used to relieve one from pain in any part of his body, any more than it says that ether may not be used to render him in- sensible for a surgical operation. It simply does not recognize this treatment as curative, and no more is it. These statements have been made, and these illustrations used almost ad nauseam, but no consideration of the claims of similia as law is complete which does not define accurately the borders of that field within which similia proposes to establish its claims. The question may be raised, In removing a parasite from the alimentary canal do I not cure my patient ? No, you do not, if you use the word cure with the meaning we have fixed upon as that which it shall have in this paper. Cura- tive treatment does not affect primarily a cause attacking man from without. Your treatment is most useful, but it is prophylactic, not curative. In removing the parasite you remove the cause of whatever disturbance your patient's health has been suffering, and what would, had it persisted, have caused prolonged disturbance : it is probable that when this cause is removed his health will be reestablished without any curative treatment. Mutatis mutandis, the same may be said of local treatment in other parasitic diseases, of antiseptic treatment in wounds, etc. Similia Similibus Curantur? 9 In defining the meaning which cure should have in this paper I have not, of course, intended to repudiate accepted definitions of that word, and under some of those definitions treatment which removes parasites, or effects ends analogous to such removal is curative : indeed the etymological mean- ing of cure does not preclude palliation or even hygiene and nursing from recognition as curative treatment, but I find no impropriety in limiting the meaning which cure shall have while considering the claims of similia, as we have limited that field outside of which similia has no claims to assert. Both Webster and Worcester authorize applying the word cure to persons or to diseases. One hears advocates of similia say that treatment under that law is a treatment of patients, and not of diseases. The idea is, I think, pre- cisely correct. This treatment does not attempt to directly destroy those morbific agents which affect man from with- out,—when that can be done it is on principles other than the one of which similia speaks : what it does attempt is to effect a cure by so modifying the processes of the vital powers that they shall resist morbific influences. Whether in every case disease has its cause in the external world of nature need not be discussed here. Where such cause exhists it bears to the disease either the relation which the intestinal parasite does to the illness which his presence occasions, or that which an infectious germ does 10 Similia Similibus Curantur? to the disease to which it gives rise : the direct removal of that cause when practicable is prophylactic, and may leave the patient in circumstances to recover. Until that cause is discovered in the case of a given disease — and a fair question is whether all diseases have such a cause in the external world — or where the removal of that cause is im- practicable, or where one is already infected in such a way that the removal of that cause will not relieve him, is it not reasonable to try to cure under guidance of similia ? II. It is conceivable that pure empiricism, /.