» ►Sflfrv V WBA H885) 1880 63580350R NLfi OSlb^TT 1 NATIONAL LIBRARY OF MEDICINE >< * ">7Z25jte ~j > -^ 3> • •>• » > *> ..» ;3s? =e^> "2. SURGEON GENERAL'S OFFICE LIBRARY, ANN*X Section — No. 113, W.D.S.G.O. NO.A11JA& 3—613 » ~> » :> > > > -> 2 "> > > ^> S£> . - * ^ T» ■ > > s>> .~>^ . ■> > * 5s> ~>^> . ^» . • ^ ■ -■> > J> >> 3T2> ^> ► 2> ^J> *> > ^>^X> > > >> >Z^-^f>> > s. »> >>- > i > ^a ">.» -■••>>• . >» ■> * > > 3__., > > >^> ■> > >^> ^>^>3C> i^S»^> -;^r^ > ^>J » J> £> ~I>^ ~> J> T5 o> ' > 7> ■ >* .^_ p» - —y „>*=> •> v> ~\>' > > ■> :> v»C^ E> T> >; iZ3 DUE TWO WEEKS FROM LAST DATE I MAR 3 tt** ^> * > • - -■ V2> _>► GPO 322808 , ,r>. > 1=1 >• ■ _■> ^s> i> > ,■'■ > •>» ^> >•> > -> :i> > ^ ^ —' » ^•^ ^* > >.» » > ■ ■ > > » » ^ > >1> > > ,5 "> v> ■> J t> } > > > ^> > > » -> > J> > J> > » ">• J> > > z» > j> > r» > 3 '^ ^ > - > » 2J- >> ~> > > >>: > > 5 ' "3JC ■■'>* MlrtfifififiililW^^ AA»' M' «of, "pain"], literally, "pain in the heart." The term is commonly ap- plied, however, to the uneasiness (heartburn) connected with indigestion, the seat of which is really in the stomach. Relieved by bicar- bonate of soda, bismuth, and guarded diet. (See Indigestion.) Carditis, inflammation of the heart. See Endocarditis and Pericarditis. Ca'ries, a term used to designate both open ulcer of bone and chronic ostitis or inflam- mation of the connective tissue of bone, with solution of the earthy part. It begins as an inflammation, accompanied by perios- titis, followed by exudation of new materials and softening. Sometimes the bone-cells are filled with a reddish fluid, and there are masses of tubercle. After caries has existed for some time the abscess bursts; its aper- ture remains open, discharging a fluid which contains particles of bone. If a probe be passed through this opening, it will be felt to sink into a soft, gritty substance; this is cari- ous bone. It is molecular death of bone, while necrosis is death of a large mass of bone. Caries usually selects the vertebrae, the bones of the wrist and foot, and the soft THE FAMILY PHYSICIAN. 15 ends of long bones forming joints. Carious vertebrae yield under the weight of the trunk, and the spine curves forward or to one side. In joints the part enlarges, the cartilages become affected, matter forms, and amputation of the limb or excision of the joint is frequently necessary. The causes of caries are constitutional, such as bad nutrition, syphilis, old age, and other depressing conditions. It may be accident- ally determined by any irritation, such as a blow or exposure to atmospheric changes. The treatment consists in supporting the patient by judicious change of air, by the use of tonics, such as cod-liver oil, which in scrofula appears to combat the constitutional predisposition. In those parts where the dis- eased bone can be reached it may be care- fully removed, so as to leave a healthy sur- face. Caries of the teeth is a very common dis- ease. It is believed to be caused by dyspep- sia and the use of too hot food and drink, but especially by neglect to clean the teeth after eating. Cat'alepsy [from the Gr. Kara, intensive, and laufidvu, to "take"], a condition in which a person becomes more or less com- pletely unconscious, but does not fall. If standing at the commencement, he remains so during the attack, the countenance re- taining the expression the patient wore at the outset. If the limbs of the patient be placed in a new position by attendants, the position is retained. This disease is a rare one, and indeed is probably not so much a peculiar disease as a symptom of other dis- eases. It has been observed in both sexes, and may occur in insane persons or in those suffering with chorea and other ner- vous affections. The attack is usually short, but may be indefinitely prolonged. Treat- ment must be addressed to the general con- dition. Catalepsy is so rare that its charac- ter is not well understood. Cat/aract [Gr. naTap'pdicTrjg, from Kara, "down," and priywui, to "break," so named because the ancients believed that a kind of veil fell down within the eye, obscuring vision], an opaque state of the crystalline lens of the eye, of its capsule, or both. Cataracts are thus lenticular, cap- sular, or lenticulo-capsular. Various other kinds are enumerated, such as the soft cat- aract, in which the lens is soft, and some- times even liquid ; the hard cataract, when the lens may be as hard as bone, with many of intermediate consistency. Lamellar cat- aract affects a limited part of one or more of the lamellae, or layers of the lens. " Gold-leaf cataract" is of a shining yellow, and con- tains cholesterine and crystalline degenera- tion-products. Cataract is generally white, but sometimes is brown, black, bluish, sil- very, etc. It sometimes has a pearly lustre. Cataract begins in a gradual impairment of vision, some months generally elapsing before sight is lost. The pupil is sensitive to light and atropia, vision being clearest when the pupil is large. There is no pain or intolerance of light. The patient sees as in a mist, but almost always can perceive at least the presence of light. The pupil on examination is seen to be opaque, but the eye is neither hardened nor softened, and the expression of the face is quite natural. One or both eyes may have cataract. It is most frequent in elderly persons, but may occur at any age; children are sometimes born with it. Medical treatment for cata- ract is useless, but the skilful surgeon can treat the disease often with the happiest results. The operation is either (1) extrac- tion of the lens and its capsule, (2) depres- sion or couching of the same, or (3) lacera- tion with appropriate instruments, with a view of inducing absorption of the diseased part. This last operation is the most com- mon, and often is the only one admissible. Great care should be taken for a long time to prevent inflammatory action. The place of the lens is supplied by a kind of specta- cles called cataract glasses. By these means the sight is often to a great degree restored. Catarrh/ [from the Gr. Kara, " down," and piu, to "flow"], in medical language is a condition characterized by hyperaemia (or congestion) of the blood-vessels of any mu- cous surface, with great increase of the prop- er secretion of the part. Thus, there may be catarrh of the nose, the throat, the air- passages, the bowels, the vagina, the blad- der, or the urethra; but in popular lan- guage " catarrh " designates either a " cold " in general, a " cold in the head," or a chron- ic catarrh of the posterior nares (nostrils) and throat. Catarrhs in general arise from exposure to cold and wet and to sudden atmospheric changes. They are most com- mon in persons who are ill-fed, and who are not accustomed to out-of-door exercise. The variety of catarrh known as a " cold "is by no means always easy of cure. The popu- lar belief that " a cold must have its run " has some foundation. Hot foot-baths, laxa- tives, sedatives, demulcents, mild stimulants, or diaphoretics may, however, prove useful in many cases. Judicious exercise, bathing, and life in the open air tend to overcome the morbid inclination to take cold from which some patients suffer. Chronic catarrh of the posterior nostrils is an obstinate dis- ease, best treated by systematic exercise and attention to other hygienic conditions, and by the use of salt water as a nasal douche. (See Nostrils, Diseases of.) 16 THE FAMILY PHYSICIAN. Chan'cre. See Syphilis. Chick/en-Pox, a contagious febrile dis- ease, chiefly of children, and bearing some resemblance to a very mild form of small- pox. Chicken-pox is distinguished by an eruption of vesicles or blebs, which rarely become pustular or yellow, and leave only a very slight incrustation, which falls off in a few days, without any permanent mark or pit as in smallpox. It is a disease of little or no danger, the fever being often hardly perceptible, and never lasting long. It usually occurs but once in any one patient. ChiFblain [Lat.pernio], one of the second- ary effects of cold and moisture upon the human system, principally affecting the feet, hands, nose, ears, etc. Chilblains are fre- quently chronic in their character. Mild cases are marked by swelling and redness of the affected part, accompanied by intol- erable itching. The more severe forms assume an ulcerated, and sometimes even a gangrenous, character. Those troubled with chilblains should carefully protect the feet and hands from cold, should wash the feet frequently and dry them very thorough- ly, and avoid going near a fire when they are very cold. Benzoated oxide-of-zinc ointment, citrine ointment, borax and sugar of lead in oil or glycerine, tincture of iodine, sulphurous acid solution, and various stim- ulant applications are all useful. The se- verer forms may need surgical treatment. Chlorosis [from the Gr. x^uf»k, "pale green"], a disease almost peculiar to young women and girls, and usually associated with other troubles peculiar to that time of life. It takes its name from a greenish- yellow tint of the skin which some patients exhibit. There is also great pallor and debility, often disturbance of the heart's action, breathlessness, and a variously per- verted and capricious appetite. The disease is characterized by a deficiency of the cell- elements of the blood. Most cases are read- ily curable by exercise, good air, proper food and clothing, and, above all, by iron, which is almost a specific in this disease. Cho/king, the obstruction of the pharynx or oesophagus, or more rarely of the larynx or trachea, by masses of food or other foreign bodies. Choking by obstruction of the pharynx or oesophagus is sometimes relieved by the operation of an emetic, sometimes by the use of gullet-forceps, of which there are many varieties, or by other appropriate instruments. CEsophagotomy, or cutting, has been resorted to, but this is one of the most formidable operations of surgery, and is not often necessary. When foreign bodies lodge in the larynx, aphonia, or loss of speech, is one of the symptoms. If the substance is in the windpipe or bronchi, the surgeon may often detect its presence by auscultation. The symptoms caused by foreign bodies in the oesophagus are often surprisingly like those which occur when similar bodies lodge in the air-pas- sages. These symptoms are various; there may be spasmodic coughing, redness of the face, ineffectual attempts to swallow, and great discharge of saliva, and generally there is great difficulty of breathing. Sur- gical aid should always be called. 'ChoFera [Gr., probably from x°^v, "bile"], a disease characterized by purg- ing and vomiting, followed by great pros- tration, and in many cases by fatal collapse. Comparatively mild cases occur with fre- quency even in temperate latitudes, and are known as sporadic cholera or cholera mor- bus ; and such cases, though very distress- ing, are seldom fatal, while the more severe or epidemic form (known as Asiatic chol- era) appears to arise in India, where it is endemic, and to be carried by ships, cara- vans, religious pilgrimages, etc. westward to Egypt, Persia, and Arabia, and thence to Europe and around the world by the regu- lar channels of commerce. The disease is probably of miasmatic origin, and local conditions may favor or check its local development; but whether the disease ought to be called contagious or not is one of the most warmly disputed points in medicine. It is certain that habitual per- sonal contact with the sick is often not fol- lowed by the disease. It is held by many that the disease is propagated by drinking- water ; by others, that its germs are taken up from the air the patient breathes. It is regarded by many as certain that the dis- ease is largely propagated from the stools or alvine discharges of the sick; and all such discharges should be treated with powerful disinfectants, and deposited, if possible, in places not frequented by those who are well; and especial care should be taken not to let them be thrown into vaults and privies in common use. Without describing the various stages of the fatal disease—the premonitory painless diarrhoea, the alarming and profuse purga- tion which follows, carrying off the fluids of the body, the profound collapse, the reaction, with the dangerous febrile condition which may follow—it is enough to say that treat- ment should be chiefly preventive. No diarrhoea in a cholera season should be ne- glected. Opiates will usually control the precursory diarrhoea. During the active stage of the disease cold compresses to the bowels are sometimes useful. The adminis- tration of diffusive stimulants in small doses during the stage of collapse should be per- sisted in. Friction by the hand may relieve THE FAMILY PHYSICIAN. 17 the spasm of the muscles. Great care should be taken for a long time lest a relapse should occur. The food of convalescents should be of the very lightest and blandest character for some days. ChoFera Infantum, or Acute Intestinal Catarrh/. This intense and dangerous form of infant diarrhoea is mostly found in hot climates, the hot season, and close air; more amongst the poor than the rich. The usual cause is improper feeding in hot weather. The former is a direct injury ; the latter, by debilitating the nervous system and lower- ing the functions of all the digestive organs, diminishes the general strength and power of endurance. Nursing infants are but sel- dom affected; many infants will recover from an attack by being returned to the mother's or nurse's breast. Still, an improper con- dition of breast-milk (an undue proportion of water, or fat, or caseine, or the admixture of medicinal agents taken by the mother or nurse, or a change produced by mental emo- tions in the latter) is known to be injurious. Weaned infants, however, and such as are brought up on artificial food, are mostly attacked. Artificial food is seldom identical, in its nutritive value, with mother's milk. Cow's milk contains less sugar and more butter and caseine than mother's milk, and requires cooking and skimming before being diluted with water (better still, barley-water). Vegetable food is dangerous unless carefully selected and prepared. Thus it is that the first passages in cholera infantum contain un- digested food of all sorts, particularly lumps of coagulated milk, which is also brought up by vomiting. Afterwards the passages are very thin, watery, of an acid or fetid smell, very copious and frequent; vomiting accom- panies this diarrhoea, more or less. Moan- ing and crying are soon replaced by debility, and even complete collapse; the body is rapidly deprived of a large portion of the water contained in it, and emaciates; the eyes lie deep in the orbits ; the sutures and fontanelles of the skull sink; the skin be- comes dry, the feet and hands cold, while the temperature of the trunk is rising; the face looks shrunk and senile; the pulse be- comes weak and frequent, the voice feeble, the expression of eyes and face listless, and stupor or coma or convulsions set in. Death is a frequent result. The principal preven- tive consists in supplying the well infant with proper artificial food when no breast- milk is available, and at regular times, and in attending to its general health. When the disease has made its appearance the principal means of checking it are the fol- lowing: during the first few (3-6-8) hours no food or drink ought to be given. The irritated stomach must be kept at rest; vomiting will cease on that condition only. After that time give a teaspoonful of ice- water or a small piece of ice (size of a bean), with or without a few drops of brandy, every five or ten minutes, as long as the tendency to vomit persists. When feeding is to be recommended, avoid milk (except breast- milk) in whatever form. Barley-water, oat- meal gruel (strained), in tea or tablespoonful doses, now and then, with the white of eggs (1-3 in twenty-four hours), will readily be taken and well digested. Many cases will get well with this dietetical treatment. At the same time the air must be kept as cool and fresh as possible, day and night. The infant will recover faster out of than in doors. The medicinal treatment, which is, under all circumstances, the domain of a physician, varies according to the nature of the case. Mercurial remedies (calomel) can be avoided. Subnitrate of bismuth, with opium in small doses, and preparations of chalk, nitrate of silver, astringents, such as tannic or gallic acids, catechu, are frequently resorted to, the latter principally in cases which threaten to become chronic. Cholera Morbus, acute gastro-intestinal catarrh in the adult. It is chiefly caused by errors of diet during the summer season, the stomach and intestines being irritated by indigestible food, acrid juices of fruits, or cold liquids at a time when the body is overheated. Vomiting, purging, paroxysms of painful colic, physical prostration, are the chief symptoms. Relief is obtained by ano- dynes, stimulants, warm enemata, and ex- ternal use of mustard draughts and hot water. Chores [Gr. x°Pe'ia, a "dance"], or St. Vitus's Dance, a disease characterized by irregular, involuntary, and often grotesque muscular action, without appreciable organic change in any tissue, and generally without pain or any known derangement of mental action or of sensation. It is most common in children after the second dentition and before puberty; much more common in girls than in boys; sometimes attacks pregnant women and other adults, though some cases once called adult chorea would now be recog- nized as locomotor ataxy, a very different disease. Chorea is sometimes hereditary, sometimes epidemic. Many writers have classed the dancing mania (the original " St. Vitus's dance"), tarantism, and the strange excesses of certain religionists (dervishes, French prophets, "jumpers," and " convul- sionists") all as varieties of chorea. Stam- mering has been called a chorea of the vocal organs. The disease is sometimes associated with rheumatism and with anaemia. Such complications should receive special treat- ment. The metallic tonics are generally 18 THE FAMILY PHYSICIAN. useful, and so are systematic gymnastics, life in the open air, and a kind and unob- trusive discipline, which shall teach the young patient the power of the will over the movements of the body. Club-Foot [Talipes). This deformity is mostly congenital, and usually affects both sides. The inner margin of the foot is ele- vated, the external one depressed and touches the ground. The deformity becomes more pronounced when the child begins to walk, sometimes to such an extent that the upper part of the foot takes the place of the sole. The leg becomes emaciated. A rational ex- planation is yielded by the consideration of the early condition of the foetus. The low- er extremities are first formed (about the end of the first month of pregnancy) on the anterior aspect of the abdomen of the foetus, under the skin, in such a manner that the knee-pit is looking towards the abdomen. In order to assume its normal shape the whole extremity, including the foot, has to turn round its axis. When this process, as far as the foot is concerned, remains incom- plete, club-foot is the result. Club-foot, when acquired after birth, results from par- alysis of the extensors of the foot. In that case the action of the flexors results in the same deformity. Mild cases require but little treatment. Manual stretching of the foot, proper bandaging, the application of a splint or plaster of Paris, are often suf- ficient. More serious cases require the cut- ting of one or more of the flexors (tendo achillis, plantar aponeurosis, anterior tibial muscles), with bandaging or the wearing of an appropriate apparatus (Scarpa's shoe). CoFic [Lat. colica; Fr. colique; from the Gr. KUAuidq, "pertaining to the colon"], a term applied to diseases attended with severe pain of" the abdomen; its supposed particu- lar connection with the large intestine is not always certain. The disease is caused, at least in part, by irregular contractions of the muscular coat of the intestines. This com- plaint arises from various causes and ex- hibits different symptoms. It is sometimes attended with constipation, and ceases when the regular action of the bowels is restored. A good remedy in such cases is a dose of castor oil (about one ounce for an adult), with twenty or twenty-five drops of laudanum. Warm baths and fomentations are often necessary. When colic resists mild and simple remedies, medical assistance should be procured, for colic is closely allied, as a symptom, to several severe and dangerous diseases. Painter's colic arises from the ab- sorption of lead into the system, and there- fore attacks persons employed in lead-mines or using preparations in which lead is used. This latter disease is often called colica Pic- tonum, or " colic of the Pictones," the latter being the ancient name of the inhabitants of Poitou, where this disease was once com- mon. (See Enteralgia ; also Biliary Colic and Renal (kidney) Colic under article Cal- culus.) Co'ma [Gr. nuua, " heavy sleep"], a medi- cal term signifying a state of lethargy or unnatural profound sleep. It occurs in apo- plexy, epilepsy, and other diseases of the brain. The patient is quite or nearly in- sensible to external impressions. Coma is also seen in narcotic poisoning. In the fatal forms the breathing is stertorous, the pupils of the eyes dilated, insensible to light, and immovable. Concussion [from the Lat. concutio, con- cussum, to " shake violently " (from con, in- tensive, and quatio, quassum, to "shake")], in surgery, the disturbance caused by a fall or blow. In all severe injuries a concussion or shock is caused to the nervous system, which may require the assiduous care of a physician. (See Shock.) Concussion of the Brain [Lat. commotio cerebri] sometimes causes alarming symp- toms, even to suppression of the functions of the brain, yet without any apparent or- ganic disease. Slight concussion of the brain (popularly called "stunning") causes vertigo, loss of memory, tinnitus aurium, and stupefaction; but these are temporary. When more severe, there is loss of sensation and volition, with vomiting, the patient be- ing apparently in a sound sleep, but without stertorous breathing. The pulse is variable, being more rapid and feeble than in com- pression of the brain; the extremities are cold. Little can be done until reaction oc- curs, when the case can be treated according to general principles. In some cases of con- cussion it is necessary to use local or general stimulants, but usually moderate heat ap- plied to the surface, abundant supplies of air, and proper adjustment of the injured parts are all that are required until con- sciousness is partly restored, when a small portion of wine or other stimulant may be useful. The effect of these should be care- fully noted, and the patient should be placed in a comfortable position in bed during the process. In all cases absolute rest is essen- tial. If the concussion has been severe, the patient is often not secure until a long time after, even though apparently well, for serious nervous lesions may be slowly de- veloped. Congenital Diseases. These must be dis- tinguished from hereditary diseases, which may show themselves either soon after birth or at some later period, and from malforma- tions of the infant, resulting from either an . arrest of development or a disease of the THE FAMILY PHYSICIAN. 19 foetus contracted during its intra-uterine life. Congenital diseases proper are—1st, transmitted from the diseased mother either before or during birth; 2d, acquired during birth, without a direct maternal influence; 3d, acquired shortly before birth. To the first class belong puerperal fever and pri- mary syphilitic and gonorrhoeal infection; to the second, asphyxia, atelectasis (unex- panded condition) of the lungs, and cephal- haematoma (sanguineous tumor upon the head); to the third, acute fatty degenera- tion of the foetus and newly born. Puerperal fever is transmitted from the mother; the blood of the babe is infected. The principal symptoms are high fever, abscesses in the subcutaneous tissue, particularly around the joints, erysipelas, and a severe form of jaun- dice. It terminates fatally within a limited number of days, rarely weeks. When the vagina of the mother is infected with syphi- litic ulceration, the child is subject to be attacked with a, primary ulceration. When it is the seat of gonorrhoeal discharge, it gives rise to the most dangerous forms of purulent inflammation of the eyelids, which, unless treated at once, is apt to result in blindness. The treatment consists in abso- lute cleanliness; the eyes must be opened frequently and washed out with water. Ice is applied constantly to the outside, and a solution of nitrate of silver to the inside of the eyelids. Asphyxia is mostly seen after protracted labor or abnormal presentation of the child, the breech or the feet being born before the head. The child is born almost or apparently lifeless, blue or pale, with no respiration and no pulsation of the heart. Artificial respiration is brought on by slapping the buttock of the babe, by al- ternately placing it in warm and cold water, by slapping its breast with a wet cloth, by swinging it forcibly in the air, by the appli- cation of an electro-magnetic current to its chest. When the surface is very blue a few drachms of blood may be allowed to flow from the untied umbilical cord. Atelectasis depends on an absence of the normal expan- sion of the lungs which follows the entrance of the air. The muscles of the chest may not be sufficiently developed, or their inner- vation may not be satisfactory from some disease of the brain, or the lungs may be inflamed or filled with mucus or some for- eign substance introduced into them during birth (blood, mucus, amniotic liquor, etc.). Emetics will empty the lungs (tickling of the fauces is sometimes sufficient), mustard plasters and the electrical current excite the nerves, and the above-mentioned methods of inducing respiration will restore the nor- mal action. Congestion [Lat. congestio, from con, j "together," gero, gestum, to "carry" or | "heap"], fulness of blood, or hyperaemia. Congestions are either active or passive. Active congestions are always essential ! parts of a further morbid process, such as inflammation. Passive congestions are often determined by some mechanical cause of obstructed or retarded circulation. Active congestions of the brain or lungs are in themselves very alarming symptoms of dis- ease ; while the passive congestions, result- ing from cirrhosis of the liver or from organic disease of the heart, are fruitful causes of local or general dropsies. Congestive Fever. See Intermittent Fever and Remittent Fever. Constipation [from the Lat. con, inten- sive, and stipo, to "stow," to "crowd," refer- ring to that state of the rectum in which it is impacted with fecal matter], a condition of the system marked by sluggish action of the bowels upon their contents, due either to diminished secretion of the juices of the mucous membrane or to a want of action of the muscular coat of the intestines. Seden- tary habits predispose to constipation, and so does too large a proportion of animal food. Brown bread, ripe fruits, fresh vegeta- bles, and active exercise tend to avert this disorder. An abdominal compress of cold water, covered with a flannel bandage, sometimes proves beneficial. For many cases the use of mild cathartics is necessary. They may be taken in proper doses for many years without bad effects. The use of nux vomica in small daily doses is often useful, and the same is true of belladonna in some constitutions. It is frequently ad- visable to employ enemata of warm or cold water, and also kneading or careful manip- ulation of the abdomen. But perhaps the most rational treatment is a careful read- justment of the diet and the adoption of active habits of life. Ill-chosen and ill- cooked food, perhaps the most frequent cause of intestinal troubles, should be espe- cially avoided. There is no doubt also that habitual constipation may in some instances be overcome by the persistent and system- atic attempt to perform the impaired func- tion at a regular time each day. Consumption [Lat. consumo, consumptum, to "wear away "], the popular name of vari- ous diseases characterized by a wasting of the body, such, for example, as " anaemia " (known as "consumption of the blood"), but applied especially to phthisis pulmonalis, a very common and very fatal disease of the lungs. It has long been taught, upon the authority of Laennec, Louis, and Andral, that the characteristic symptoms of pulmo- nary consumption depend upon the presence in the lung-tissue of a new growth, or neo- 20 THE FAMILY PHYSICIAN. plasm, called Tubercle (which see); but the studies of Virchow, Niemeyer, and other recent pathologists have demonstrated that cases of originally tuberculous consumption are quite rare, although they do occur, the presence of the tubercles giving rise to local pneumonic inflammation in their neighbor- hood ; while ordinary consumption is gener- ally characterized by (1) local consolidation, (2) cheesy degeneration of the solidified spot, and (3) destruction of the degenerated tissue and formation of a cavity. This is the direct result, in most cases, of a " catar- rhal" inflammation—that is, of an inflam- mation of an epithelial surface, such as lines the air-passages—the inflammation being associated with a free discharge of mucus from the surface of the membrane. Next, the air-vesicles of the lungs become filled by inhalation and by other means with the young cells of the secretion. If, as in non-fatal cases of ordinary pneumonia, these cells soon undergo liquefaction and absorption, the patient recovers. But if the accumulation of cells remains unabsorbed in the air-vesicles, it suffers a cheesy degen- eration, a sort of slow decay. It appears that an inflammatory process is set up around this caseous degenerate mass, and that the cheesy degeneration is soon present in the inflamed lung-tissue itself. After a time the degenerate mass may assume a more or less complete purulent form, and may be discharged by coughing. This, however, does not always happen. The mass may be absorbed, the pulmonary tis- sue become indurated and callous, without a trace of tubercle; the bronchial tubes may become dilated, and the disease, spread- ing slowly, may disorganize but not con- sume the lungs. This is a very common condition in old consumptive cases. Mean- while, the less changed bronchi near the seat of the disease pour forth a profuse catarrhal secretion, causing copious expec- toration. The pleura near the seat of the disease becomes thickened, and adheres by organized exudations to the wall of the chest. In the majority of cases these changes begin at the apex of one or both lungs. The first subjective symptoms are usually dull pains about the collar-bones, tightness across the chest, and there is frequently a dry, hacking cough in the morning and late at night. Headache, weariness, dyspepsia, and loss of appetite are often present. The pulse increases permanently, in most cases exceed- ing 90 or 100 beats in a minute. The rapid- ity of breathing is usually increased. An early symptom is a high evening tempera- ture—103° or 104° F. In the second stage night-sweats are often extremely severe, pus is freely expectorated, hectic fever is deci- dedly present, the pulse is more frequent. In the third stage, when considerable cavities often form in the lung, the preceding symp- toms are much intensified; colliquitive diarrhoea supervenes, and yet in many cases the patient continues serene and hopeful, and the mind is remarkably clear and active. The causes of consumption are very nume- rous. Niemeyer assigns the first place as a cause to that depraved, ill-nourished state (called the scrofulous diathesis) in which there is a tendency to the increased produc- tion of young cells. Any depressing circum- stance may tend to the establishment of consumption. An hereditary tendency is one of the most important of these circum- stances, but any depressed state of the parent, especially of the mother, whether consump- tion, starvation, anaemia, scrofula, or any other dyscrasia, appears to have a nearly equal effect on the offspring. Bowditch and others have shown that, other things being equal, it is most frequently observed in places where the air and soil are charged with moisture. Cold weather in itself appears to have little or no tendency to produce the disease, but a very changeable temperature is one of its most fruitful causes. There has been considerable discussion as to whether consumption is or is not a con- tagious disease; and facts are not wanting which appear to show a danger of infection, especially to those who take care of and intimately associate with consumptives. Another interesting question is whether consumption is ever caused or promoted by habitual drunkenness, either in the case of the drunkard or of his offspring. The best opinion among physicians appears to be that while in selected cases alcoholic stimulants may be useful adjuvants, the remedy is a dangerous one, since there is no doubt that many more consumptives are injured than are benefited by it. On the offspring of the consumptive the effect of hard drinking is confessedly deplorable. Over-study at school appears to develop the disease in some young people. Overwork, factory-life, the grinding of metals, cabinetmaking, and all kinds of dusty or sedentary work are undoubtedly prolific sources of the disease. Mental trouble, excessive care, too frequent child- bearing, and sexual excess are to be reckoned in the list of causes. Consumption fre- quently follows measles, typhoid fever, and whooping cough, not improbably resulting from the bronchitis which accompanies those diseases. It is also thought that pregnancy will check the disease in the female; and while there are numerous observations which go to show that for the time the disease is some- THE FAMILY PHYSICIAN. 21 times (but not always) held in abeyance, it is certain that this abeyance is often followed by a period of greatly increased activity; and the probability that a child born in such circumstances will be sickly and short-lived ought to prevent the resort to any such practice as a curative measure. The physical signs of consumption are those which are determined by inspection, palpation, auscultation, and percussion of the chest. Their relative importance can be appreciated by none except the well-trained and experienced diagnostician. The treatment of consumption cannot be di-eu^-ed except in the most general terms, for no disease is less amenable to mere routine treatment. Yet there is no reason- able question that, especially in its earlier stages, this disease is a curable one. One of the first requisites is the establishment, if possible, of normal nutrition—a process which is usually much impaired in those liable to this disease. The use of such tonics as quinia and strychnia in some conditions, the administration of cod-liver oil, either as food or for its assumed alterative powers, and judicious change of climate, are among the most useful measures. Alcoholic stimulants benefit some patients and injure others, and on the whole do more harm than good; the hypophosphite-; of soda and lime appear to cause increase of weight and diminution of cough and expectoration in many cases; thorough counter-irritation of the chest- walls is a very important adjuvant; the wearing of sufficient clothing to protect the body from sudden changes of temperature is not less important. Systematic, and even severe, physical labor benefits some patients, but others appear to be injured by any but the gentlest exercise. Special symptoms, like diarrhoea and night-sweats, will require palliative treatment. Life in the open air is advisable, except in wet and bleak weather. The dry air of the Western plains and of the Rocky Mountain region, the equable weather of Florida, and the dry, sandy soil and bal- samic exhalations of the great pine forests of the South, are believed to afford favorable conditions for recovery in many cases. Much depends on the peculiar history and tem- perament of individual cases, and the proper appreciation of these conditions is likely to tax the judgment of the ablest practitioner. Contu sion. See Wounds. ConvuFsions [from the Lat. convello, con- vulsum, to " pull violently "], an acute nervous affection occurring in paroxysms, during which the patient loses consciousness, the muscles of the body are spasmodically con- tracted, and the limbs first stiffened and twisted, then agitated by irregular involun- tary movements. The face is distorted, the eyeballs rolled upward, the teeth clenched, biting the tongue, which protrudes at the beginning of the attack. Respiration is ar- rested by the stiffening of the chest-muscles and by closure of the glottis; the patient grows black in the face, and froth oozes from the mouth, and sometimes from the nostrils; the veins of the neck swell. After some time the muscles relax again, respira- tion is restored, the agitation of the limbs ceases, the patient either returns entirely to consciousness or falls into a heavy sleep, which may last several hours. The appear- ance and the nature of the attack are the same in the convulsions of epilepsy and in the so-called eclamptic convulsions of chil- dren or of women in childbirth. They may result from any cause that first irritates and then suddenly abolishes the functions of the brain and spinal cord. Convulsions occur, therefore, in diseases of the nervous cen- tres; in diseases of other organs of the body, that transmit irritation to these centres; finally, in morbid conditions of the blood which interfere with their nutrition. Lender the first head may be mentioned congestion or anaemia (bloodlessness) of the brain, in- flammations, tumors, finally premature ossi- fication of the bones of the head, by which the brain becomes subject to abnormal pres- sure. In other cases more obscure there seems to exist in the brain and cord a con- genital susceptibility to irritation, and con- sequent exhaustion of functions, so that the most trifling circumstance may occasion a convulsion. It is then that are observed the convulsions of hysteria and of epilepsy. The latter is only distinguished by the con- stitutional tendency that persists during the intervals of the attacks, and suffices to cause their removal. The hysterical convulsion, however, offers some peculiarities, and con- sciousness, though perverted, is not abol- ished, the interference with respiration is less complete than in typical eclampsia, and leads to involuntary laughing and crying; there is no lividity of the face or frothing at the mouth; the return to consciousness is immediate, without the transition stage of heavy sleep. Neither the irregular con- vulsive movements of chorea ("St. Vitus's dance," "clonic" muscular contractions) nor the rigidity of tetanus ("tonic" mus- cular contractions) are sufficient to consti- tute a convulsion in which the two forms of muscular contraction are combined, the last occurring at the beginning, the first at the end of the attack. Convulsions dependent on transmitted ir- ritations occur principally in children. They may occur spontaneously, owing to a con- genital predisposition by which normal phys- iological processes become irritating, or they 22 THE FAMILY may be excited by inflammation of the gums in dentition, by indigestion, by worms, by the invasion of acute diseases, as pneu- monia or eruptive fevers; by some acci- dents, as extensive burns. Women in child- birth are liable to convulsions of a similar character, which may be excited by the mere act of parturition. This dangerous complication (puerperal eclampsia) is more frequently, however, associated with an al- teration of the blood that is liable to occur during pregnancy, and due to transient kid- ney disease (nephritis). The kidneys act imperfectly, and hence part of the elements of the urine that should be secreted by them are retained in the blood, poisoning it, while at the same time part of the albumen of the blood passes off in the urine. These con- vulsions are therefore called albuminuric or uraemic, and afford most striking illus- trations of the morbid influence of altered blood upon the nerve-centres. They occur also in genuine nephritis or Bright's disease, and in that which often complicates the sec- ond and third stages of scarlet fever. Vari- ous mineral or narcotic poisons introduced into the blood have a similar effect to urae- mia in causing convulsions. Any convulsion may prove fatal if the arrest of respiration be sufficiently pro- longed. The danger varies very much ac- cording to the cause, the uraemic convulsions of women in childbirth [puerperal eclampsia) being far the most frequently fatal. After them may be successively ranked—uraemic convulsions in primary nephritis, or that complicating scarlet fever, and those caused by narcotics (opium) or mineral poisons (lead). The treatment of convulsions may some- times be addressed exclusively to the cause, as in the last three cases just mentioned, where the danger of the paroxysm itself is known to be small. In the other cases, where life is liable to be endangered by the duration or rapid repetition of convul- sive attacks, these urgently demand relief. Means of relief are—1st, compression of the carotids; 2d, alcoholic stimulants ; 3d, vene- section ; 4th, chloral; 5th, chloroform ; 6th, anti-hysterical medicines ; 7th, warm baths; 8th, cold applications to head. Each is adapted to a special ■ case. Compression of the carotids has been used principally in idiopathic epilepsy (where, as said, the par- oxysm itself is often left without treatment). It is intended to relieve the congestion ex- isting at the base of the brain, and has sometimes proved successful. Cold appli- cations are used for the same purpose, and may be combined with the other methods of treatment. Stimulants are only used | where the convulsion results from haemor- j PHYSICIAN. rhage or inanition. Venesection may be required in cases of intense venous conges- tion of the brain, as indicated by extreme lividity of the face and distension of the veins of the neck. It is most often needed in puerperal convulsions. Large doses of chloral are especially useful for infantile convulsions, or for those of scarlet fever, or during the interval of attacks to prevent their renewal. Veratrum viride is a power- ful agent to lower the pulse and increase the force of the heart's impulse; hence it may be used in the same cases as venesection, to dissipate the stagnation of blood in the veins. The warm bath may be used in nearly all cases, except perhaps in puer- peral convulsions, where it may be con- tra-indicated by the difficulty and danger of moving the patient. An hysterical convulsion may be treated with the nervous stimulants formerly called antispasmodics, especially assafoetida, va- lerian, ether (internally). Corn [clavus), [from cornu, a "horn"], a horny accumulation of epidermic cells upon the surface of the human foot, produced by the pressure of the boot or shoe. Corns may be softened by hot water or poultices, and the horny part can be carefully removed with the knife. When painful, they may be generally much relieved by the occasion- al application of a solution of nitrate of silver. Various surgical appliances have been devised for the relief of corns, which when neglected may give rise to serious trouble. Corpulency. See Obesity. Cos'tiveness. See Constipation. Cough [Lat. tussis], a physiological act or operation, which consists in the sudden ex- pulsion of air from the lungs, at the begin- ning of which act the glottis is closed. Coughing is designed for the expulsion of foreign or secreted matters from the air- passages. It is largely a reflex action, gen- erally arising from local irritation. When the irritation is the result of disease, cough- ing may be a very important symptom. It is partly voluntary and partly involuntary. A cough may sometimes be relieved by ex- pectorant remedies, by mucilaginous diluent draughts, by warm foot-baths, by stimu- lants, and very often by small doses of opium or of other sedatives. CoxaFgia, or CoxFtis [morbus coxarius, " hip-joint disease"), a chronic inflammation of the hip-joint, which may begin either in the head of the thigh-bone or the socket of the hip-bone, or else in the membrane {sy- novial) that lines its cavity, but which finally extends to all its tissues, cartilages, liga- ments, and surrounding soft parts. Inflam- mation of the bones {osteitis), by far the THE FAMILY PHYSICIAN. 23 most common origin of the disease in chil- dren, is chronic and insidious in its devel- opment, and is favored by the incomplete ossification and active nutrition of the bones in childhood. Inflammation of the lining membrane [synovitis) is the most frequent form of hip disease in adolescence, and then is often of rheumatic origin. Chronic in- fantile coxitis principally affects children between one and five years of age, and is often awakened by a fall or blow, especially when such accident occurs to children of a lymphatic or scrofulous constitution. The very first symptom is lameness, followed by pain, first felt in the knee, afterwards ex- cited in the joint itself by direct pressure, by motion'of the limb, or by the weight of the body resting upon it. To lessen this weight the patient rests on the ball of his toes, and drags the leg in walking, stiffly extending it. At this stage it is turned a little outward by spasmodic contraction of the muscles on the outer side of the joint. But very soon, in order to still further lessen the weight, the body bends over on the thigh, and the arm and lame part of the back, with the abdomen, are carried for- ward. When the patient lies down, there- fore, a space is left between the body and the bed, and if the spinal column be forcibly straightened out and the curve flattened, the thigh in turn is bent on the body by drag- ging of the muscle that runs from the spinal column to the head of the thigh-bone [psoas). Still, for the purpose of lessening weight, the hips are tilted towards the painful side, and appear oblique, while the leg is thus apparently lengthened. Behind, the nates are flattened. It soon becomes impossible to glide the head of the thigh-bone in its socket; the whole hip moves with every motion communicated to the leg. This sign is most characteristic of the confirmed disease; it is due first to the spasmodic rigid- ity of muscles—later to inflammatory ad- hesions. In the second stage liquid is poured out into the cavity of the joint to increase the space of this cavity, the thigh is more strongly bent on the body (flexed), and drawn inward (adducted), so that the foot crosses the opposite leg. The affected limb is therefore apparently shortened. A swell- ing appears in the groin and at the outer aspect of the thigh; the pain becomes in- tolerably severe; standing and walking are impossible. In the third stage the cavity fills with matter, the ligaments of the joint are re- laxed, abscesses form in the neighborhood, and all the soft parts are swollen by inflam- matory exudations. Dislocation occasion- ally though rarely occurs. More often the head of the thigh-bone separates from its shaft and adheres to the socket of the joint, while the socket itself is enlarged. The patient's strength is severely undermined, hectic fever sets in, the emaciation is ex- treme, and death may occur gradually from exhaustion, or more rapidly from acute ab- sorption of pus. The diagnosis of morbus coxarius is only difficult in the first stage. The lameness may simulate that of muscular paralysis, from which it is distinguished by the free- dom with which the head of the thigh-bone may be moved; or the pain in the knee may fix suspicion on the wrong joint; or the thigh may exactly imitate hysterical muscu- lar contraction; but in this affection-the limb relaxes completely under chloroform. The prognosis for spontaneous cure is always very unfavorable. After suppura- tion death may be caused by pyaemia, by exhaustion, by general tuberculosis, or by amyloid disease. Appropriate treatment of the first and second stages offers about 50 per cent, of recoveries; operative treatment of the third stage has so far cured about one-third of the cases submitted to it. In a large number of cases, although the in- flammation is arrested, and hence life is saved, the joint becomes permanently im- mobilized (ankylosis) by fibrous bands with- in and around its cavity, that hold the ar- ticular surfaces firmly together (false anky- losis). This result is to a certain extent favored by the treatment adopted for the cure of inflammation; it is important there- fore that the stiffened limb be left in the most favorable position for use—namely, extension. The treatment varies according to the stage of the disease. During the primary osteitis that so often precedes inflammation of the joint, and is indicated by the one symptom of lameness, constitutional treat- ment is to be adopted—cod-liver oil, iron, cinchona, nourishing food, fresh air, and salt-water bathing. As soon as the move- ments of the joint are compromised, local treatment becomes of primary importance. It aims—1st, to immobilize the joint, so as to prevent friction of the inflamed parts; 2d, to extend the limb, so as to separate as much as possible the folds of the lining membrane, to reduce to a minimum size the cavity of the joint, and thus favor the re- absorption of fluids; finally, to leave the limb in the best position for use should it become permanently stiffened. The limb can only be maintained in extension by a force sufficient to overcome the spasmodic muscular contractions. Many apparatuses are devised for this purpose, in which the limb is straightened out and fastened to an 24 THE FAMILY inflexible plane, and forcibly retained in this position by means either of a weight attached to the foot or a sliding screw at the knee. The simplest form of apparatus is made by swathing the limb in bandages stiffened by plaster of Paris or dextrine. These are only adapted to the earliest stage, or when cure is already progressing. It enables the patient to walk about. This facility is also afforded by steel apparatus that supports the limb at the waist and foot, and gradually extends it by continued trac- tion at the knee. In other cases the patient is kept in bed, the leg fastened to a simple long splint, with a cross-piece under the foot, to which is attached the weight. A large double gutter, in which were laid the entire pelvis and both lower extremities of the patient, was formerly famous, but is now seldom used. During the employment of such apparatus ice may be applied to the joint to subdue acute inflammation, occa- sionally blisters, where fluid has been rap- idly effused, more often pressure by means of elastic bands, a powerful means of pro- moting reabsorption. When suppuration has occurred within the joint, and especially when pus has dis- charged externally by one or more fistulae, it is necessary to amputate (resect) the head of the thigh-bone. Very extensive destruc- tion of the hip-bone and certain general dis- eases, amyloid disease or general tuberculo- sis, with uncontrollable diarrhoea, contra-in- dicate the operation. After it, death may result from such complications or from sur- gical fever (pyaemia, septicaemia). When successful, however, the patient is rescued from an otherwise certain death, and the joint recovers its integrity, ankylosis being much less frequent than after treatment by immobilizing apparatus. Creeping PaFsy. See Cp.uveilhier's Disease and Progressive Muscular Atrophy. Croup. All the forms of croup have one thing in common—viz. an obstruction (ca- tarrhal or inflammatory) in the interior of the larynx, particularly on the vocal chords. The milder form is called " false croup " or " pseudo croup." The larynx is reddened, its mucous membrane swelled, and its secre- tion of mucus usually increased. Thereby the passage of air through the larynx is im- peded, and spasmodic action of its muscular apparatus effected. It is frequently found in children who have before suffered from "colds," especially from catarrh of the throat and enlarged tonsils, and who have been too carefully kept from the contact with cold air and cold water. The attack of " pseudo croup " is sudden or preceded by nasal or bronchial catarrh. It takes place PHYSICIAN. after the child has been asleep for some hours. It wakes up about midnight with a barking cough, loud and laborious respira- tion, small and frequent pulse, and more or less fever. In bad cases the veins of the neck and face swell, the face is bloated and bluish, and suffocation appears imminent. This attack may last from half an hour to six hours. It terminates in perspiration, the cough becoming moister, the voice being hoarse, but may return in the next night. Some children are apt to have many attacks in the course of many years. There are no membranes in the throat, no glands swollen round the neck. A very severe attack re- quires an emetic (powdered ipecac, sulphate of zinc, sulphate of copper, turpeth mine- ral) ; milder attacks require very little or no treatment. Let the child drink a little hot milk at short intervals. It must not sleep longer than an hour at a time, and should take a drink on waking up. Put a mustard plaster round the neck, or apply cold water at short intervals. Where the throat is sore, ice-pills every five or ten minutes; where in- halation is very spasmodic, half a teaspoon- ful of paregoric (one dose) or one grain of Dover's powder. Treat the consecutive gen- eral catarrh for four or five days with uni- form warm (not hot) temperature of the room, warm water inhalations (kettle on the stove), small doses (hourly) of ipecac, or an antimonial preparation or muriate of am- monia. Where there is a chronic catarrh of the throat (dryness, redness, swelled ton- sils, hacking cough, snoring), a teaspoonful of glycerine as a preventive at bed-time. While this " pseudo croup," commonly called " croup," is a very mild disease—we have never seen a case terminating fatally— the other form, or "true croup," "mem- branous croup," is very dangerous. Under ordinary circumstances, and with a treat- ment exclusively medicinal, ninety out of a hundred die. It consists sometimes in sim- ple inflammatory swelling ("laryngitis"), but usually in the obstruction of the larynx by a deposit of a whitish, grayish, or (through admixture with a little blood) darker " croup- ous " or " diphtheritic " membrane. The de- posit may take place upon or into the normal tissue of the organ. It seldom originates in the larynx; sometimes ascends from the trachea; mostly descends from the throat, where it is discovered in one or more small spots or over a larger surface. In excep- tional cases it extends over the interior sur- face of the nose, and the mouth. Such de- posits may be known to exist for days; they will then descend, result in hoarseness, in- creasing to complete absence of voice (apho- nia), and in great difficulty of respiration, with final suffocation. When the deposits THE FAMILY PHYSICIAN. 2o cover the whole interior of the larynx, both inspiration and expiration are impeded, and aphonia is complete. When they result in serous (watery) swelling of the larynx (espe- cially the posterior insertion of the vocal chords) only, expiration is easier and the voice not entirely suppressed. The first stage is either that of throat diphtheria or of a simple catarrh only, which is attended with but little fever, and therefore little thought of. It may last a few days. In the second stage (twelve hours to fourteen days) the symptoms of obstruction show themselves; the voice is hoarse, and at last absent; respiration is slow, labored, and loud; the muscles of the neck and chest exerted to their utmost; the insertion of the diaphragm drawn in with every inspi- ration, deep grooves forming with every in- spiration above and below the clavicle, the child tossing about, supporting itself on its knees, and throwing the head backward. The lips begin to exhibit a bluish hue. This symptom (cyanosis) increases in the third stage, where the influence of the in- sufficient oxygenization of the blood is more visible in general paleness, bluishness, in sleepiness, in the frequent and irregular pulse, in the cool surface, convulsive twitch- ings, and loss of consciousness. Unfortu- nately, the latter symptom is not constant, many children dying with undisturbed in- tellect. Death is the result of direct suffo- cation, or the result of a complication of the disease with bronchitis or pneumonia. Me- dicinal treatment is very unsatisfactory. We seldom succeed in dissolving and re- moving the membranes. Nitrate-of-silver applications to the larynx have justly been discarded. Inhalation of diluted lime-wa- ter through an atomizer or of lactic acid in glycerine and water (1: 8-10) has proved successful in a few instances. Emetics are of use in such cases only where the mem- branes are known to be partially loosened (peculiar flapping sound in respiration), or when the presence of mucus, in addition to a membrane, proves dangerous. Ice-pills frequently, ice applications to the throat, moist air, 1-2 grains of chlorate of potassa in a teaspoonful of water every |—1 hour; inhalations of carbolic acid, either through an atomizer or sprinkled through the room; muriate of ammonia evaporated on a stove or hot coal,—all such means may be tried, but not to such an extent as to interfere with a copious supply of pure air, the effect of which may still be improved by inhala- tion of oxygen gas. Where the disease runs its course with fever, quinia, seldom aconite or veratrum. Most cases will resist treat- ment. Twenty or twenty-five per cent, will be saved by tracheotomy, an operation con- sisting in the artificial opening of the wind- pipe below the obstructed larynx. This opening in the trachea is kept patent by means of a silver or hard-rubber tube in- serted in it until the disease has disappeared from the larynx. The relief given by this operation is surprising, and although the mortality after its performance is still very great, death is almost always easier, result- ing more from exhaustion than from suffo- cation. Cruveilhier's Disease. See Progressive Muscular Atrophy. CystFtis [Gr. mnc, the bladder], inflam- mation of the bladder. It may be acute or chronic. It is more frequent in men than in women. It may be the result of blows, kicks, bruises, punctured or incised wounds. It also occurs from holding the urine too long, from urine which is irritating—either highly acid or very alkaline—or from the irritation of calculus and gravel in the bladder. In men it frequently results from gonorrhoea of the urinary passage; in old men, from enlarged prostate (neck of the bladder), causing constant detention of alkaline urine; and in women, from inflammations and diseases of the uterus and pelvic cel- lular tissue. The symptoms are chilliness, fever, nausea and vomiting, prostration of strength, pain and sense of heat over the bladder, constant desire to urinate, often with inability to do so, and the voiding of urine thick and creamy like pea-soup, which under the microscope is found to be full of mucous and pus cells, epithelial scales from the bladder, and frequently blood. The treatment consists in applying in some cases ice-packs over the bladder, in others hot poultices and fomentations sprinkled with laudanum, opiates and chloral by the mouth to allay pain, the free use of alkaline and demulcent drinks, and the withdrawal of the urine by the catheter twice daily if practicable, and washing out the bladder with tepid or cool water, medicated or carbol- ated. In chronic cystitis in men the urine must be regularly drawn and the bladder washed out. If stricture exist, it must be dilated or incised. In women an artificial opening into the vagina is sometimes made to cure the bladder by constant free drainage. Deaf'ness, loss or imperfection of hearing, may be congenital or acquired, permanent or temporary, complete or partial. It may be (1) " nervous;" (2) the result of local dis- ease or accident. (See Ear, Diseases of.) DelirFum Tre/mens [i. e. "trembling de- lirium"), a morbid affection caused by the action of alcoholic drinks, and often afflict- ing hard drinkers after severe accidents or attacks of acute disease. Delirium, tremb- ling and subsultus of the muscles and ten- 26 THE FAMILY PHYSICIAN. dons, wakefulness, and rapid pulse, are cha- racteristic symptoms. The patient sometimes suffers extremely from the most frightful ap- prehensions, and frequently thinks he sees grotesque and horrible objects. The tongue has a thick furry coat, the skin is generally cool and covered with sweat, and the patient gives forth a characteristic saccharine odor. The blood and fluids of the brain are loaded with alcohol, and often (especially in old patients) there are abundant degenerative changes in the brain, lungs, liver, etc. Death occurs in about one-sixth of the cases. The mortality appears to have been formerly much greater than at present. The treat- ment is various. Sleep may be induced by the use of chloral or bromide of potassium, and in long-continued cases opiates may be cautiously administered with the happiest results. Patients nearly always call for al- cohol in some form, but this desire should not, as a general rule, be gratified. The strength should be kept up by beef-tea, milk, raw eggs, etc. Cinchona bark or qui- nine should be given as a tonic, and chloral, bromides, and valerian to secure sleep and allay excitement. Dengue,* den'ga, a disease known by the names of dunga, dandy, breakbone fever, etc., an epidemic, seldom fatal, which has prevailed at different times in the southern parts of the U. S. and in the East and West Indies. Its symptoms are headache, fever, pain and swelling of the smaller joints, an eruption of the skin, and gouty pains which often cause lameness for a considerable time. It appears to be of a rheumatic character. Diabe'tes [Gr. SiajSr/r^g, from Sid, "through," and flaivu, to "go"], the name of two dis- eases characterized by the excessive excre- tion of urine; whence the name. Diabetes insipidus (now called Polyuria, which see) is distinguished from the other much more dangerous disease by the fact that the urine consists chiefly of water. It is neither fre- quent nor formidable. But Diabetes mellitus, sweet" or "honeyed diabetes" [Mellituria), is one of the most incurable and serious of diseases. The urine has its specific gravity greatly increased by the presence of diabetic sugar, a substance believed to be identical (in most cases) with liver-sugar, and very closely approaching grape-sugar in its com- position and reactions. In some cases it ap- pears to be muscle-sugar [inosite). The dis- ease is further characterized by indigestion, intense thirst, wasting, prostration of mind and body, and in many cases by degenerative changes in the tissues. Its causes are ob- scure and its treatment not well understood. * Dengue is the Spanish for " dandy " or " fop," and is applied to this disease on account of the re- markable stiffness of the patient's motions. Some cases are greatly benefited by opium and the use of strictly nitrogenous food, like bran or gluten bread and skim-milk. Tem- porary diabetes has been observed after the administration of woorari poison and other drugs. Diarrhce'a [didppoia, from did, "through," and piu, to " flow"], a disease characterized by frequent soft alvine discharges; acute or chronic intestinal catarrh. Many writers have drawn nice distinctions between the various assumed varieties of this disease, which indeed is very frequently a symptom rather than a distinct disease; but nearly every case is in reality due to inflammation or irritation of some part of the intestinal canal. Diarrhoea as a symptom of cholera, dysentery, typhoid fever, pulmonary con- sumption, and some forms of peritonitis, is treated of under these respective heads. When resulting from local or general disease of the alimentary canal, its symptoms and treatment vary greatly according to the age of the patient. In infants both its acute and chronic forms are very frequent and fatal. These cases often depend on im- proper food and clothing—less frequently upon disturbances caused by dentition than is generally supposed. These cases require, first, a careful attention to hygienic con- ditions. Flannels should be worn next to the skin. If a milk-diet should disagree, as it often does, finely-cut raw beef or strong broth may be given to the child. Medi- cation should generally be cautious, but active. Many children suffer or die from over-medication, and still more, probably, from lack of active treatment. If scy- balous masses of fecal matter exist in the bowels, they should be cleared out by cathar- tics, such as rhubarb, etc., with aromatics or castor oil. The proper use of astringents, tonics, and opiates in infantile diarrhoea is a matter requiring much discrimination. Chronic diarrhoea in the adult is an obsti- nate and rather common disease. A certain proportion of the cases are improved by iron, quinia, salicine, and other tonics. Change of climate, visits to mild saline chalybeate springs, sea-bathing, etc. are useful in many instances. Balsam of co- paiba relieves some patients with surprising readiness. Astringent remedies, as kino, catechu, and opiates, have much value as palliative, and sometimes as curative, agents. The " diarrhoea and cholera mixtures" for adults contain usually astringents, opiates, chloroform, capsicum, and camphor. In the simple acute diarrhoea of temperate climates adults previously well are in gen- eral promptly cured by these agents, ju- diciously administered. Diphtheria [from the Gr. 6iag, an " elephant," because it was fancied that the legs of those who suffered with it resembled those of an elephant], as at present used, designates the disease anciently known as elephantiasis Arabum, the " elephantiasis of the Arabians," so called to distinguish it from the elephantiasis Graicorum, the " ele- phantiasis of the Greeks," which was prob- ably identical with leprosy. Elephantiasis is rare in Europe and North America, though not unknown in either. It is endemic in the Levant and the East and West Indies. The foot and leg, or sometimes other parts, become greatly enlarged and enormously in- creased in density and hardness, the skin as- suming a remarkable roughness and usually a darkness of hue. The prognosis is usually grave, very few cases recovering, though many cases remain completely stationary after the disease is once established. In fatal cases suppuration and erysipelas are the active symptoms. The treatment is thus far unsatisfactory. The use of iron, iodine and quinia, with bandaging, is rec- ommended. Em bolism [Gr. EfifioAiofidg, from kv, " in," and (3dAAu, to "throw"], in pathology, is the presence of a clot [embolus) in the arteries or veins. Some writers also apply the name to the fixed venous clot [thrombus). Embolism in the brain is a recognized cause of hemiplegia and of an apoplectic form of seizure in many respects identical with the phenomena of true apoplexy or cerebral haemorrhage. An extensive embolism of the lungs may lead to sudden death; a smaller one may lead to local pneumonia, abscess, pyaemia, or gangrene. Embolism, though frequently fatal, is sometimes followed by recovery. Endocarditis [from endocardium and the termination -itis, denoting "inflammation"], an inflammation of the endocardium. It is generally of rheumatic character, and, though not often immediately fatal, it is a frequent cause of organic disease and de- formity of the heart and its valves. It is frequently associated with pericarditis, and its occurrence is one of the results always to be feared in rheumatic fever. It is usu- ally attended by pain or discomfort about the heart, and is detected by auscultation. It produces peculiar murmurs in the heart, the significance of which can only be ap- preciated by the trained physician. The disease is very intractable. Sedatives, such as hydrocyanic acid, belladonna, aconite, and digitalis, may be useful in acute stages! The alkaline treatment for rheumatism is often advantageous. Salicylic acid and salicylate of soda are the most recent and effectual remedies. Patients some- times, though not very frequently, entirely recover. EnteraFgia [from theGr. hrepov, the "in- testine," and dlyog, "pain"], a name given in some medical works to colic, especially of the form attended by spasmodic contrac- tions in the muscular coat of the intestine. The disease is best relieved by hot applica- tions, anodynes, hypodermic injection of morphine, and by the cautious use of chlor- oform. The tendency of late writers is to limit the use of the term enteralgia to cases of Neuralgia (which see) of the intes- tines. Enteritis [from theGr. IvrEpov, "bowel," "intestine," and the termination -itis, de- noting, in modern medical nomenclature, "inflammation"], an inflammation of the small intestines. Active inflammation of the bowels, in adults at least, is frequently confined to the peritoneal coat, and the dis- ease is hence called peritonitis. When the mucous coat of the bowels alone is actively involved, it is frequently a fatal disease in children, but in adults, with care, the ma- jority of cases recover. Catarrhal enteritis is benefited, and generally cured, by gentle purgation. But in active disease of this kind cathartics will often greatly aggravate the evil. Such cases are best treated by rest, opiates, poultices to the abdomen, and bland nourishment. " Typhlo-enteritis " or inflam- mation of the caecum, when caused by ab- scess or perforation of the appendix caeci is not unfrequently fatal; when otherwise caused, recovery is to be looked for. Epilepsy [Lat. epilepsia; Gr. iTtil^ia, from km, "upon," and Aau/3dvu, to "take," to "seize"], a disease of the nervous system, in which there are occasional seizures or fits of sudden and complete loss of conscious- ness, usually associated with convulsions which become clonic, and finally impede respiration. The attack may last from two to twenty minutes, and is followed by ex- haustion and sleep. In other cases, called petit mal (Fr. for "little sickness"), the loss of consciousness is but momentary, and there is no convulsion or falling down, as in ordi- nary attacks. It has been customary to say that this disease is merely functional, because in most cases there is little or no apparent organic change of the brain observable THE FAMILY PHYSICIAN. 31 after death; but the present opinion of pathologists appears to be that sufficiently careful observation will detect lesions, how- ever minute, sufficient to account for the symptoms. Dilatation of blood-vessels in the medulla oblongata is frequently ob- served. The disease itself is of a fright- ful character, apart from the unhappy effects it may produce upon the mind of the patient. When occurring in childhood, and espe- cially during the period of dentition, it may after a time be spontaneously cured. It is sometimes hereditary, and often is caused by various excesses, by blows on the head, or by excessive fright. The treatment during the paroxysm, if it be habitual, is simply to place the patient where he cannot hurt himself, to loosen his clothing, and give him plenty of fresb. air. Between the paroxysms the patient should avoid all excesses of eating, of drinking, or of any other kind. Systematic exercise, and even gymnastics, never carried so far as to produce much weariness, are often beneficial. Nutritious food, with avoidance of coffee, to- bacco, and stimulants, is usually advisable. Of medicines, the bromides of potassium and of ammonium are useful in warding off the attacks, and the continuous use of the bromides for a term of one or two years will effect a cure in many cases. Tonics, such as iron, arsenic, and quinia, are useful in spe- cial cases, but in others are apparently worse than useless. Notwithstanding the terrible effects of this disease upon the minds of many of its vic- tims, not a few distinguished men have been epileptics, as were Cambyses, Caesar, Mo- hammed, Petrarch, Henry IV. of England, Napoleon, and Byron. The ancients, it is said, sometimes called this disease morbus basilicus ("king's disease"), from the idea that great men were especially liable to it; and among its numerous names was morbus sacer (the "sacred disease"), because the gods were believed to have especial care over its victims. Epistax/is. See Nose-Bleed. Erysipelas [Gr. EpvainsTuig, probably from epvdpog, "red," and ireAog, akin to the Lat. pellis, "skin"], a disease probably of mias- matic origin, sometimes associated with a peculiar rose-colored eruption of the skin, whence the name. The inflammation at- tending this disease is of a peculiar low type which j# but little understood. It may ter- minate favorably by resolution, less favor- ably by abscess (which is apt to be diffuse— i. e. not limited to a single spot—and is then very dangerous), or the termination may be in gangrene and the death of the patient. The disease is very common in military hos- pitals, seating itself in wounds, when it proves frequently fatal. Erysipelatous dis- eases sometimes assume an infectious and almost an epidemic character. Puerperal fever, peritonitis, phlebitis, and a long cata- logue of diseases of low type are akin to erysipelas. Its infectious character is ad- mitted. The famous old " Dreadnaught" hospital-ship in the Thames became so poi- soned by it that she had to be destroyed. The best treatment is a sustaining one. Pure air, a milk diet, and the use of quinia and iron, with stimulants, are in general indi- cated. The sulphites and other disinfectant remedies may be employed. Externally, it is safest to use only the blandest applica- tions—carbolized lotions, lead and opium wash, etc. Eye, Diseases of. See articles Amaurosis, Granular Lids, Blindness, Cataract, Myopia, Squinting, Ophthalmia, Sight, Defects of, etc. Facial NeuraFgia, paroxysmal pain in the head and face. The cause of the neur- algia is a morbid state of the nervous cen- tre giving origin to the nerve (trigeminus); and this morbid state may itself be the re- sult of simple malnutrition (anaemia), of blood-poisoning (malaria), of inherited pre- disposition, of irritation of other sensitive nerves (bad teeth), tumors pressing on the nerve, and inflammation of the nerve itself. Remedies are anodynes and external use of hot water and soothing lotions. Fa/cial ParaFysis, a paralysis of the su- perficial muscles of the face, due to a loss of the motor property of the nerve supply- ing them—the seventh or facial nerve. The symptoms are loss of expression on the affected side of the face, a drawing of the mouth and features, generally to the opposite (healthy) side, inability to close the eyelids on the palsied side, slight impairment in articulation, owing to palsy of a part of the muscles of the tongue. When both sides of the face are palsied, the face appears like a smooth mask, the mouth (lips) is open, the eyes cannot be closed. The pathological conditions which produce this palsy may be disease of the cerebrum, pons Varolii, or of the medulla oblongata, pressure upon the nerve in the skull or in the canals in the petrous bone, injuries to the nerve in these locations or upon the face, or the sudden impact of cold air upon the face (draught). FainFing [Syncope), a more or less com- plete and sudden loss of sensation and of the power of motion, usually attended by feebleness of the circulation and respiration. Fainting is due to anaemia of the brain, its proximate cause; more remotely it may be caused by loss of blood, by profound emo- tional disturbance, or by heart disease. In 32 THE FAMILY PHYSICIAN. profound and protracted syncope there is danger of death by heart-clot. Fainting is to be treated by placing the patient on his back in a horizontal position, or with the head and chest slightly depressed below the level of the rest of the body; by admission of fresh air to the patient; and, in prolonged eases, by applying diffusive stimulants—as ammonia, camphor to the nostrils, alcoholic stimulants by the mouth and rectum, and resorting to artificial respiration and the electric battery. Fainting is seldom fatal, unless in cases of severe disease. FalFing of the Fun/dament. See Rec- tum, Diseases of (prolapse). FalFing of the Womb. See Prolapsus Uteri and Uterine Diseases. Far-Sighiedness. See Sight, Defects of. Fat'ty Degeneration, in pathology, a con- dition in which the minute structural ele- ments of the tissues of living organisms are gradually replaced by fat-globules. In man this diseased condition has been observed in nearly all the tissues, though some authorities state that the nerves and the red corpuscles of blood are not liable to this change. Fats, though always of organic origin, and often closely associated with living tissues, are never, it is believed, truly organized bodies; and consequently they are not regarded as ever truly vitalized, any more than are the water and the lime which are found in liv- ing organisms. In this view, fatty degen- eration is a molecular death of the tissues. In the liver at first it is merely an excess of the normal fatty element, which, however, encroaches upon the organized elements of those structures, and becomes a true fatty degeneration. It attacks the muscles, the heart, the bones, the brain (yellow soften- ing), the cornea [arcussenilis), and the kidney in many cases of so-called Bright's disease. Fa'vus [Lat. "honeycomb"], or Scald Head {i. e. "scabby head," from scall, a "scab"), a disease formerly known as tinea and porrigo, generally seated on the hairy part of the scalp, but sometimes attacking the roots of the nails and other parts. This disease is caused by a parasitic vegetation. These fungi are known as Achorion Schoen- leinii and Puccinia favi, but are now believed to be abberrant forms of the species known as the yeast-plant, Cryptococcus cerevisoz. Fa- vus is a contagious disease, best prevented by cleanliness, and best cured by carefully removing the hair and applying parasiticide medicines, such as have the power of de- stroying low organisms. Sulphurous and carbolic acids and weak solutions of corro- sive sublimate are the best applications. It leads to permanent baldness. Febric'ula [a diminutive of the Lat. febris, "fever"], or Ephem'eral Fever, a short fever- ish attack lasting from one day to a week, marked by a rapid pulse, a furred tongue, and often by a very considerable increase of heat and by headache. Persons suffering from febricula are said to be "threatened with a fever," and are too often improperly dosed. A warm bath, warm or cold water to drink as best suits the patient, the use of enemata if called for, and other simple treat- ment is sufficient, for the disease will pass away of itself if allowed to do so. It is often followed by an eruption or a stage of profuse sweating. Febricula may be asso- ciated with a severe cold, a profound emo- tional disturbance, or with some excess on the patient's part. It is especially common during epidemics of typhoid and typhus fevers. FeFon. See Whitlow. Fe/ver [Lat. febris, allied to ferveo, to "glow," to " be hot"]. In distinction from other diseases, which, however grave or extended, are confined to certain organs, fever may be said to be a perversion of all the physiological functions. Fever oc- curs in a great variety of forms and differ- ent degrees. The early symptoms are a sensation of general malaise, bodily and mental languor, headache, pains in the back and limbs, loss of appetite, accelerated pulse, and chill; af- ter a certain length of time a sensation of heat, not merely felt by the patient himself, but also by others. The skin feels hot and dry, the pulse remains quick, but is fuller, the respiration is hurried and irregular, the general restlessness becomes very great, the thirst intense, the appetite is wholly lost, the tongue is coated with a whitish film, the mucous membrane of the mouth and throat is dry, the urine is scanty, of a deeper color but clear, and of a greater specific gravity. After this stage of dry heat there is profuse sweating, the dryness of the mouth and the thirst diminish, the respiration becomes deeper, more regular, and less frequent, the pulse soft. Not all the symptoms just described must necessarily be present to pronounce a certain condition of the system as febrile in cha- racter. One symptom is never wanting in fever, which can be measured with mathematical exactitude, which always keeps in true re- lation to the degree of the fever: it is the increase of the temperature of the body as determined by the thermometer. It varies from 98.5° F. (normal temperature of the body) to 108° F., or a little more (37.5° to 42° C.). There is no more certain and trust- worthy guide to a correct judgment of the dangers threatening health and life from THE FAMILY PHYSICIAN. 33 fever than the thermometer, and it is now universally adopted by the medical profes- sion as a means of diagnosis and prognosis in levers. Fevers are idiopathic (primary) and symp- tomatic (secondary), idiopathic fevers are also called essential fevers. All zymotic fevers, be they contagious or miasmatic, belong to this class. Symptomatic fevers require a local disease as a preceding con- dition. Such are inflammatory, catarrhal, rheumatic, hectic fevers; also all fevers named after the organs whose diseased condition causes them—brain, lung, gastric, enteric fever. Contagious and infectious fevers are the result of peculiar substances, which get into the circulation either from the air we breathe or in food and drink. Secondary fevers are generated in a similar manner, the local diseases producing some substance which, absorbed, contaminates the blood in such a way that fever must follow. (The more important varieties of fever are described, with their treatment, under their alphabet- ical heads.) Fe'ver and A'gue. See Intermittent Fever. Fistula [Lat., a "pipe"], a term used in pathology to designate an abnormal canal, usually of small length and diameter, lead- ing from one organ to another (vesicovagi- nal fistula), or from some cavity of the body to the external world (gastric fistula, fistula in ano). Fistula is called (1) complete, when it has two orifices; (2) incomplete or blind, when it has only one; (3) external, when the opening is through the skin; (4) inter- nal, when it opens only into a cavity of the body. The two most prominent character- istics of a fistula are the constant discharge from it of a thin purulent fluid, with which the secretions of the organ affected are mix- ed, and the obstinacy with which it resists the healing process. This latter results from the nature of the wall of the fistula, which in recent cases is formed of soft, unhealthy granulation-cells which have no tendency to unite to form either cicatrix or cuticle. In older cases the walls consist principally of condensed connective tissue, inseparable from the surrounding parts. A fistula of long standing also exerts a change in the tissues through which it passes, these be- coming more dense, and finally indurated, and the integument around its orifice cal- lous and sometimes warty. Fistula is caused (1) by wounds which penetrate passages giving natural exit to the secretions, or those which follow a long and deviating course through many tissues; (2) by ulceration and the sloughing process; | (3) by abscess. The last is the most frequent cause. The passage of a bullet through any region of the body sometimes leaves a canal which fails to unite; and whenever a necrosis of bone occurs there are usually one or more tracks following a winding course from it to the outside of the body. These passages are often called fistulae, but the more appro- priate name for them is simis. Fistula commonly occurs in persons of an enfeebled constitution. Where it results from abscess it is more frequently the chronic than acute form which gives rise to it. Fis- tulae Were formerly supposed to furnish exit for morbid humors, and surgeons hesitated to attempt their cure. At the present time some surgeons refuse to operate on a fistula in ano in a patient having phthisis. The cure of fistula depends upon producing union of its walls through the agency of healthy granulation - cells. This may be brought about by stimulating applications, as the injection of nitrate of silver, corrosive sublimate, etc. in solution, or the applica- tion of the red-hot iron. Where the walls are old and indurated, it is necessary to dis- sect them out and remove them altogether, bringing the lips of the wound together by sutures. Fit. See Convulsions, Apoplexy, and Epilepsy. FlaFulence, the accumulation of gas, the product of fermented food, in the stomach, consequent upon indigestion (see Indiges- tion and Dyspepsia), or in the intestines, where it is detained by faeces. (See Con- stipation.) Flatulence causes gurgling or rumbling sounds in the bowels, and may be voided by belching of wind by the mouth or downward from the rectum. It is the fre- quent cause of colic or intestinal cramp. (See Enteralgia and Colic.) When hab- itually present, it dilates the bowels and creates a large abdomen. The appropriate remedies are those detailed in the treatment of indigestion and constipation. Flu'or AFbus. See Leucorrhcea. Frac/ture [Lat. fractura, from frango, fractum, to "break"]. In surgery, the term fracture is used to indicate a rupture, or solution of continuity, occurring in os- seous tissue, or in rare cases in cartilag- inous tissue partly ossified. By simple fracture is meant one in which no wound exists admitting air to the seat of frac- ture. A compound fracture is one in which such a wound does exist. A complicated fracture is one in which some other seri- ous injury is inflicted, at or near the site of the fracture, or in which, from the sit- uation of the rupture, the healing process cannot progress as favorably as is usual; 34 THE FAMILY PHYSICIAN. as when a large blood-vessel or nerve-trunk is torn by the broken bone, or when the fracture extends into a joint-cavity. A com- minuted fracture is one in which the bone is broken into several small pieces at the point of rupture, and is rarely produced except by direct violence, as by a blow or crushing force. A complete fracture is one in which the rupture extends through the whole thick- ness of the bone, while if only a portion of the fibres are broken, as sometimes hap- pens in children, the fracture is called in- complete, or the "green-stick fracture" of some writers, from its resemblance to the fracture produced by bending a stick of green wood until some of the fibres give way. The terms transverse, oblique, and lon- gitudinal refer to the direction of the rupture in relation to the long axis of the bone, the great majority of the fractures of the long bones belonging to the second class. The term stellate is applied to a series of fractures radiating from a centre, as seen sometimes in fracture of the skull from a wound pro- duced by a pointed instrument. Causes of Fracture.—These may be external, from violence adequate to break a normal bone, or internal, the bone being too fragile to resist ordinary forces. External causes embrace direct violence, where the rupturing force is applied opposite the point where the bone breaks (as a blow or crushing force which fractures the bone at the point of contact); and indirect violence, where the bone is bent beyond the power of its elasticity to restore itself, and gives way, usually at some distance from the point of application of the fracturing force (as when a fall upon the shoulder fractures the collar- bone). Muscular force is generally acknow- ledged as a cause of fractures, especially in particular situations—e. g. fracture of the point of the elbow or of the knee-pan. The internal or predisposing cause is a brittleness of the bones called " fragilitas ossium," which occurs sometimes in early or middle life as a result of disease (although it may occur in those otherwise healthy), and al- most universally in advanced life from the preponderance of earthy and deficiency of elastic matter. The signs of fracture are pain, swelling, and tenderness at the point of fracture, change in shape of the limb, false point of motion, and crepitation, though any, or even all, of these signs may be absent. The pain comes from laceration of some nerve-filaments and pressure upon others by the broken bone, or by the blood escaping from torn vessels, which gives rise to the swelling that occurs at first, the subsequent swelling being due to products of inflammation or of the reparative process. The change in shape is due partly to this swelling, and partly to displacement of the broken bones either by muscular action or by movements of the patient. The false point of motion comes of course from the want of continuity of the bone, and the crepitation is a fine gra- ting elicited when the ends of the broken bone are gently rubbed together, and which may be appreciated by the ear or touch. If the fracture be impacted—that is, if the broken ends are firmly locked together, as sometimes happens — none of these signs may be present in a marked degree, and some of them, such as crepitation and false motion, not at all. Fractures generally unite by the deposi- tion of bony material between and around the broken ends of the bone, forming an exception to the rule that prevails for most other structures, that union after rupture is effected by means of fibrous or connective tissue; and the reason is apparent, since fibrous tissue does not form a sufficiently rigid bond of union to enable the bone to perform its functions, as we see in cases of so- called "ununited fracture," when the union is of a fibrous nature. The union of a sim- ple fracture consists of two processes—one to accomplish a temporary purpose, the other for the permanent union ; the former to support and bind together the fragments, while the latter consolidates them. A few days after the fracture the bone, its perios- teum (membrane surrounding the bone), and the neighboring tissues pour out a quantity of plastic material around and be- tween the broken ends, which gradually hardens, and at the end of the fourth week consolidates the fragments. This is called the " provisional callus," and the hardening process continues until it is converted into bony tissue. The plastic material effused between the fragments is much slower in ossifying than that which is internal or ex- ternal to it; and this, which is destined to form the permanent bond of union, is called the " definitive callus." While the defini- tive callus is forming the provisional callus is gradually being absorbed; and finally, many months after the fracture, the provis- ional callus entirely disappears, and the fragments are united by the definitive callus alone, which is true bone; and the site of the fracture may be indicated only by a slight enlargement at that point. The union of compound fractures is entirely different. In these the provisional callus is almost or quite absent, and the definitive callus is formed by a process of granulation from the ends of the fragments, the granulations being gradually converted into bony tissue. It is a process requiring several months, or sometimes years, and is attended with a THE FAMILY PHYSICIAN. 35 greatly increased amount of danger from exhaustion through long - continued sup- puration and absorption of purulent mate- rial. The difference in the mode of union seems to be due to the irritation produced by the air, or something conveyed by the air to the wound. The treatment of fractures consists essen- tially in restoring the fragments to their original position, and holding them there by some form of rigid apparatus which shall not cause discomfort or injury to the pa- tient. Of course general treatment is to be employed also if the circumstances require; but simple fracture in a healthy individual requires no special medication or system of dieting, as the old modes of practice were wont to inculcate. The rigid apparatus used to retain the fragments in their proper position is called a splint, which consists of two kinds—padded and moulded. If the splints are made of straight, inflexible ma- terial, they cannot be adapted to the irreg- ularities of the limb without more or less padding at certain points; while if made of material which at the time of its appli- cation is soft and pliable, it may be moulded to the shape of the limb, and, becoming hard and rigid, will serve to support and retain the fragments. Splints of the first variety are made of wood, sheet iron, tin, zinc, etc., while gutta-percha, felt, sole leather, starch, soluble glass, or plaster of Paris are used for the second class. Frac- tures sometimes fail to unite, and are called ununited fractures. This may be the con- sequence of faulty position of the fragments, or of something interposed between the broken ends, impeding union, but it more frequently arises from some constitutional defect. The location of the fracture may prevent union, especially if either fragment be poorly supplied with blood, as in certain fractures of the neck of the thigh-bone, which frequently unite only by fibrous tis- sue. Ununited fractures may often be made to unite by irritating the parts at the site of fracture, as by rubbing the bones to- gether, drilling them by means of a long needle, or by wiring the bones together. Frost-bite and Freezing are conditions caused by the action of cold upon the ani- mal economy. Frost-bite is local and par- tial—freezing is general and more or less complete. Severe frost-bite may lead to gangrene, but the milder forms often result in nothing worse than chilblains, which are very annoying, but not dangerous. General freezing, if rapid, may result in speedy death ; but more frequently the vital func- tions pass for a time into a state of abey- ance, which may last, it is said, for some days, and then be terminated by death. In recovering frozen and unconscious persons it is held that a very slow restoration of the normal temperature is safest, apparently be- cause sudden warmth arouses those dormant energies which demand immediate aeration of the blood, which failing, death at once ensues. Fu'runcle. See Boil. Gall Stones. See Calculus. Gan/grene [Gr. ydyypaiva], the death, or partial death, of an organ or any portion of the body. Debility from any cause, and especially from old age, is the great predis- posing agency. Among the exciting causes may be mentioned mechanioal injuries and obstruction either to the ingress of arterial blood to, or egress of venous blood from, a part. The' immediate cause of the death of a part is always the complete cessation of the capillary circulation in it. A distinc- tion is generally made into wet and dry gan- grene, according to the condition of the part affected. Another division is into constitu- tional and local. Gangrene usually begins with a diminution in the sensation and tem- perature of the part, the cuticle becomes detached, and a serous fluid is found beneath it. The limb crackles under the finger, owing to the presence of gases which are evolved by the decomposing tissues. These symptoms increase until all sensation is lost, and the part becomes colored greenish-black by the sulphuretted hydrogen set free during the process. The treatment must necessarily vary according to the cause. The system should be supported, and inflammation, if present, allayed. If there be any chance of saving the part, the temperature should be kept up by warm fomentations. GicFdiness! See Vertigo. Gleet, the chronic stage of urethritis, deeply seated and most difficult of cure. (See Gonorrhoea.) Goitre (gutter, the "throat"); synonyms, Bronchocele, Derbyshire Neck. This is an enlargement of the thyroid gland, which lies across the front of the windpipe. It probably originates in hypertrophy of the natural gland-structure, and the concurrent formation of cysts in tbe interstices of the gland-tissue. These cysts are of varying size, and generally contain a more or less solid glairy matter, blood, earthy concre- tions, etc. The disease has been supposed to be due to the drinking of snow-water, but it occurs where there is no snow. Al- though manifesting itself to a greater or less extent in all parts of the world, it is more prevalent in the chalky parts of Eng- land, especially Derbyshire and Nottingham, and in mountainous districts, among which may be named the Himalayas, Andes, Alps, the Tyrol, and the valley of the Rhone. It 36 THE FAMILY PHYSICIAN. is seen upon almost all cretins. Goitre is also a symptom of a peculiar affection known as Graves' or Basedow's Disease (which see), which consists, besides the enlargement of the thyroid gland, of an unusual promi- nence of the eyeballs and a very rapid ac- tion of the heart. This tumor, called ex- ophthalmic goitre, is not goitre at all, and usually disappears with the general disease. [Niemeyer). Unless it be very large, goitre causes but little inconvenience, but it often attains to such a size as to produce serious trouble by pressure on the neighboring im- portant parts—the large veins, trachea, oesophagus, etc. The treatment usually adopted is iodine, both applied externally and administered internally, to cause ab- sorption. Extirpation is sometimes per- formed. In India powerful mercurial in- unctions are successfully employed. Gonorrhoea [Gr. yovh, "semen," and />ew, to " flow," a misnomer], acute catarrh of the urethra, a disease which is usually of impure venereal origin. It is a painful disease, and may result in the chronic catarrh called gleet, or may lead to stricture, epididymitis, en- larged prostate, and other serious evils. Its treatment should be entrusted only to prac- titioners of the highest character. Quacks extort large sums of money from persons suffering from this disorder and its conse- quences. The most efficacious remedies are copaiba, cubebs, and sandalwood internally, and local injections of bismuth, sugar of lead, and sulphate of zinc in weak solution. (See Stricture and Gleet.) Gout [goutte, a "drop"], an inflammation of the fibrous and ligamentous parts of the joints, and is dependent upon mal-assimila- tion. It derives its name from having been thought to be produced by a liquid falling [goutte d goutte], "drop by drop," into the joints, and, although this theory has long since been proved to be erroneous, it still re- tains the name. We generally find an he- reditary predisposition to this affection. It can be traced through many generations, and is found in about two-thirds of the cases. Next frequently we find it in persons enjoy- ing the luxuries of the table, drinking wine and beer, and taking but little exercise. It was formerly considered a disease of high life, but is now just as common among the poorest people in England as among the rich. It was not so in Sydenham's time. The ballast-heavers of London have more gout than any other class in the world. They work in the water, and drink large quanti- ties of malt liquors daily. The principal change observed in the blood is a great excess of uric acid, and the deposit in the affected joints is made up almost entirely of urates. But " we neither know whether the uric-acid diathesis be the primary and chief anomaly in gout, and whether it be not accompanied by other and more import- ant changes in the composition of the blood, nor do we know the disturbances of nutrition by which one of the constant products of normal nutrition, uric acid, is formed in ex- cess." [Xiemcyer.) We have certain symp- toms premonitory to an attack of gout. The digestive apparatus is disturbed, and we find that the patient loses his appetite; he will also suffer from pain and a sense of weight or fulness in the region of the stomach, accom- panied by acid eructations, heartburn, irregu- larity of the bowels, and flatulence. Some- times he will vomit a phlegmy material. The patient now complains of a dull head- ache, and feels indisposed for any work, and becomes irascible. This last symptom is well known among the laity as a premonition of gout. The urine becomes highly con- centrated ; the specific gravity runs up to 1025-1030; it is of a deep amber or red color, and deposits on cooling large quantities of uric acid and the urates, which are com- monly known as the " brickdust deposit." This concentrated urine often causes a burn- ing and pain as it passes along the urethra, and has even been known to excite a muco- purulent discharge. Dr. Graves speaks of an unavoidable desire in these patients to grind the teeth, which is caused by painful sensations in the genital organs, and which seem to be relieved in no other way. To such an extent is this sometimes practised that we find gouty individuals with the teeth worn almost entirely away. The next symp- tom noticed is small sharp pains throughout the whole economy; this precedes the attack of gout but a few days. Now the attack begins, generally during the night, by a burning, piercing pain in the great toe, generally the metatarsophalangeal articula- tion. The patients have different modes of expressing this variety of pain—some sim- ulating it to the driving of a nail into the foot, others to the teeth of a dog crushing the bones or to having the toe squeezed in a vice. The patient tumbles and tosses from one side of the bed to the other, seeking a position in which he may get some rest; but this is denied by his visitor, who never lets go his grip for more than a couple of seconds at a time. At the end of three or four hours the pain has become almost intoler- able, and is so severe that the patient cannot bear even the weight of the bed-clothes upon the affected part. Towards morning the pain diminishes, and the patient breaks out in a perspiration and falls asleep. The following day the affected joints are found to be red and swollen, but the pain is a great relief from that of the previous night; they con- THE FAMILY PHYSICIAN. 37 tinue in this way until evening, when the scene of the previous night is re-enacted. After a week of this suffering the patient is generally temporarily freed from his trouble; the redness and swelling gradually subside, and the upper layer of the skin peels off and itches greatly. The patient now feels better than he did before the attack. After re- peated attacks the disease may degenerate into chronic gout, in which the attacks are quite frequent; there is a purplish appear- ance of the affected joints, and, owing to synovial effusions and deposits of lithate of soda, they are cedematous and deformed. Abscesses frequently form in or about the joints, and concretions of urate of soda may escape from them when opened. Nervous gout, also called atonic, anom- alous, or irregular gout, is a name given to a variety which occurs in persons of hered- itary gouty tendencies, in whom the debili- tated constitution is not in a condition to develop a normal attack of gout. It gener- ally occurs in nervous and poorly-nourished individuals, and appears as dyspepsia, cough, etc., accompanied by palpitation of the heart, irregular pulse, dizziness, syncope, etc. It is this variety which sometimes proves fatal. The only disease with which gout could be confounded is rheumatism, but it differs from it in the following points: " (1) Rheu- matism affects chiefly the young or middle- aged; gout, the elderly. (2) Rheumatism prefers the larger joints; gout, the smaller, and especially the feet and hands. (3) Gout is attended with more obvious disorder of the digestive organs; the pain is of a more burning character, and the swelling greater and more vividly red." The treatment may be divided into two stages—viz. that during the paroxysm, and that during the interval between the parox- ysms. Colchicum is the favorite drug used to cut short the attack. If the pain is ex- cessive it may be relieved by opiates. The bowels should be opened. Salicylic acid and salicylate of soda are beneficial. In the treatment during the interval between the paroxysms attention should be paid to the diet and regimen of the patient; he should take his meals regularly; should eat plenty of vegetables, meat but once a day, and should abstain from alcoholic drinks, especially ale and beer, and take a certain amount of exercise in the open air daily. The regular use of mild mineral waters, which are diuretic and laxative, tends to avert the attacks and to lessen or remove the constitutional taint. Particular attention should be taken to keep the bow- els regular. Granular Lids. See Ophthalmia. Grav'el, a disease manifested by the forma- tion of small concretions either in the kid- neys or bladder, and their expulsion with the urine. They are generally composed of some of the salts of urine, and are deposited either on account of being in abnormal abundance, or in consequence of the urine not being of the proper reaction to hold them in solution. When they form in the kidneys, they sometimes cause the most ex- cruciating pain when passing along the ure- ter to the bladder, giving rise to what is commonly known as renal colic. Gravel may be divided into three varieties, accord- ing to its composition—viz. (1) uric acid or red gravel (see Lithic-Acid Diathesis) ; (2) oxalate of lime (see Oxaluria) ; (3) phosphatic deposits (see Phosphatic Dia- thesis) . Other rare varieties are mentioned in the art. Calculus (which see). Graves' Disease. See Basedow's Dis- ease. Green Sick/ness. See Chlorosis. Grippe. See Ixfluenza. Gunshot Wounds, wounds produced by balls or other projectiles propelled by the force of an explosive, such as gunpowder, gun-cotton, or the like. They differ in some essential points from other wounds; they are generally accompanied by shock, and com- plicated by the presence of foreign bodies in the wound, such as the ball or projectile itself and pieces of clothing or accoutre- ments which the ball has carried with it and before it. Another element of their danger consists in the fact that they gen- erally occur in large numbers—i. e. in war —when the accumulation of a large num- ber of suppurating wounds gives rise to dangerous complications, such as erysipe- las, pyaemia, and hospital gangrene; add to that, that in protracted wars the constitution of the men has already suffered by camp- life, bad diet, and exposure, producing ty- phus, dysentery, scurvy, etc. When, after the discovery of gunpowder, gunshot wounds first became known, surgery being then in its infancy, these wounds were looked upon as the result of some supernatural and malif- icent agency, and were therefore often treat- ed by incantations and the like, or they were looked upon as poisoned either by the pow- der or the ball, and were treated with a view to destroy the poison—for instance, by pour- ing boiling oil into the wound. At the pres- ent day the treatment of gunshot wounds has become more simple and rational; even the extraction of the ball is no longer looked upon as of such absolute necessity as for- merly. Still, some erroneous notions have prevailed till very recently. Thus, it was maintained that the wound of exit of the ball was always larger than that of entrance 38 THE FAMILY PHYSICIAN. Recent investigations have shown that the above is not true, and that the wound of entrance is often larger than that of exit. Another mistaken idea has prevailed with regard to what was called the " wind of the ball." Recent investigations have proved that a spent round-shot may roll over a part of the body when it touches at an obtuse angle like a wheel, crushing every- thing beneath the skin, without breaking or wounding the skin itself. Taking a statistical view of gunshot wounds and their fatality on a large scale, we find that on an average the number of those killed outright on the field of battle to those wounded is about in the proportion of 1 to 5, and that of the wounded about 14 to 15 per cent, will die of their wounds. Thus, the number of killed in battle in the U. S. army during the civil war was 59,850. The number of gunshot wounds from May 1, 1861, to June 30, 1865, was 235,585; of the latter, 33,653, or 14.2 per cent., died of their wounds. The Confederate army lost 57,425 killed in battle, and had 227,871 wounded. Haematemesis [Gr.alfia, "blood," ande^ew, to " vomit"]. Vomiting of blood, or haemor- rhage, from the stomach, is the result chiefly of ulcer of the stomach, cancer of the stom- ach, or extreme inflammation or congestion of the stomach, as when caused by corrosive irritants, excess of alcoholic drinks, or the presence of serious disease of the liver. Htemorrhage from the stomach is to be dis- tinguished chiefly from bleeding from the lungs and bronchi. Blood from the stomach is vomited; it is preceded or accompanied by food, gastric mucus, and gastric juice; it is brought up with a sense of nausea and straining; it often is changed by digestive juice to a dark, coffee-ground appearance; usually there is a pain or burning sensa- tion over the pit of the stomach. Haemor- rhage from the stomach is treated by per- fect rest on the back, cold packs over the stomach, bits of ice swallowed, preventing the swallowing of food or drink for some time, feeding by the rectum or cautiously by the mouth. Opiates or other anodynes may be administered by the rectum or hy- podermically to check the tendency to vomit. Haemoptysis [Gr. alua, "blood," and TTTvaig, "spitting"], the expectoration of blood from the vessels of the lungs or from the mucous membrane of the thoracic air-passages. Haemoptysis occurs in pul- monary consumption, in heart disease, etc. It is sometimes vicarious in cases of sup- pressed menses. The significance of haem- optysis in any case can only be estimated by the trained diagnostician. The remedies usually administered for haemoptysis are di- lute sulphuric acid, ergot, gallic acid, lead- acetate, opium, turpentine, common salt, and other haemostatics. Perfect quiet of mind and body is to be sought. Ice to the chest and the swallowing of lumps of ice are often effective. HaenForrhage. See Bleeding. HaenForrhage from the Lungs. See Haem- optysis. HaenForrhage from the Stomach. See HvEMATEMESIS. HaenForrhoids. See Piles. Hair, Diseases of. See Baldness and Barber's Itch. Hay Asthma, Hay Fe'ver, or AutunFnal Catarrh', a disease recurring in certain in- dividuals at certain seasons every year, as in June (rose cold), in the hay-making sea- son (hay fever), or (in this country espe- cially) in the autumn, whence the name autumnal catarrh. It is a catarrhal affec- tion of the nasal (and sometimes of the bronchial) passages, often with some fever and more or less asthmatic spasm. Some- times incessant sneezing and coryza are the only prominent symptoms. It is not ob- served in very hot or very cold countries, on the sea, or at considerable heights in some mountain-regions. It is very probably caused by pollen from some plants, but it is by no means certain of what species they are. Removal from districts where the disease prevails is the only means of cure, but the usual palliatives may be employed. The insufflation of quinine, either in powder or a saturated solution, at the inception of the disease, is claimed to cut short the specific catarrh while yet limited to the nostrils and fauces. HeacFache (Cephalalgia) is of many kinds. It is often the result of indigestion, of ex- cess in eating or drinking, of malarial or other specific poison, of uterine disease, or of neuralgia. It is also a common symptom of many fevers and other acute diseases. If persistent headache be not relieved by a correction of the hygienic conditions as re- gards diet, clothing, exercise, etc., the case requires medical treatment, the character of which must depend upon the probable cause of the difficulty. Opiates, chloral, paul- linia, citrate of caffeine will deaden the pain; aconite, chloroform, and chloral cam- phor may be applied externally; aromatic spirits of ammonia, bicarbonate of soda, and laxatives are efficient when stomach disorder is the cause. Hearing, Defects7 of. See Deafness and Ear, Diseases of. HearFburn. See Cardialgia. Heart Diseases. Hypertrophy or en- largement of the heart is generally due to some obstacle to the circulation, re- THE FAMILY PHYSICIAN. 39 quiring increased strength of muscle to over- come it, as a diseased valve, or a tumor pressing upon a large artery, or a large or- gan so diseased that the circulation through it is seriously obstructed. It is produced by the mental emotions, which increase the force and frequency of heart-beats, as fre- quent anger and the anxieties that excite the heart. Its subjective manifestations are a strong impulse of the heart-beats and shortness of breath on exertion. The phy- sician discovers it by many signs, the chief of which is the extension of dulness on per- cussion to the left of the line of the healthy heart. The heart, once enlarged, never re- turns again to its original size, and alone it rarely causes death. This usually is the re- sult of secondary disorders, apoplexy or kid- ney disease, or it may wait for the intercur- rence of other entirely distinct diseases. Dilatation of the heart is an enlargement of its cavities. The left ventricle may be so dilated that its capacity is considerably greater than would be sufficient to contain the whole of a healthy heart. The dilata- tion may be in all of the four cavities, or may be confined to one. The ventricles are far more liable to dilatation than the aur- icles, and the left much more than the right. Dilatation and hypertrophy very commonly go together, so that eccentric hypertrophy or hypertrophy with dilatation, already ex- plained, associated with and caused by mor- bid changes in the shape and function of the valves, is the most common form of heart disease. The conditions of the heart may be regarded as alternately active and passive —active in systole, passive in diastole. If in the passive state, while the blood is flowing naturally into a heart-cavity, there is at the same time a reflux of blood into the same cavity in consequence of a defective valve, dilatation of that cavity will be sure to occur. The extended wall of such a cavity may not be thicker than it is in health, yet as it bounds a greater space it will require more material, and is hypertrophied by multipli- cation of the muscular fibres. In this state the heart has been known to weigh sixty ounces, or six times its natural _ weight. Hearts like these are enormitas cordis, or cor bovinum vel taurinum. They are almost al- ways found in persons who have had rheu- matism and heart disease in childhood, and have grown to manhood with a damaged heart. It is noticeable that children bear these cardiac affections better than adults. The body, as it grows, seems to accept and tolerate an amount of such disease that would overwhelm a grown-up person. When it begins thus early, it is usually carried to manhood, and often to advanced manhood. It is the repetition of the attack which is fatal in childhood. Dilatation with hyper- trophy is, after it reaches a certain stage of progress, attended by shortness of breath on exertion, sometimes palpitations, irregular heart-beating, and consequently irregular pulse. Its chief danger is, however, an induced or secondary Bright's disease, with dropsical swellings of the legs and body; without which the common forms of heart disease are not generally fatal. There is a form of dilatation of the heart in which there is not only no hypertrophy, but in which the walls of one or all the cavities gradually grow thinner and thinner by fatty degeneration and absorption of the muscu- lar tissue, till this tissue is almost wholly removed, and the walls are stretched and expanded in the effort to expel the blood from their cavities. But this is a rare dis- ease, and may be passed with the statement that it is possible. Simple atrophy of the heart, (diminished size and weight) occurs only with wasting diseases; it should not be regarded as a disease. Diseases of the Valves of the Heart.—En- docarditis, or inflammation of the lining membrane of the cavities of the heart, is a common attendant on acute rheumatic inflammation of the joints, but it may occur without rheumatism. This inflammation is one of the principal causes of derangement and imperfection in these essential append- ages of the heart. Thus, endocarditis ex- pends its force principally on those duplica- tions of the endocardium which constitute the valves. It deposits a new material be- tween their folds, and at first increases their thickness. A portion of this new material is converted into fibrous structure, and final- ly the fibres contract. The result is, that these valves become thick and unyielding, so that the semilunar cannot be applied to the arterial wall when the blood is forced into the aorta or pulmonary artery. The mitral and tricuspid grow stiff and hard, and do not fully give place to the blood passing from the auricle into the ventricle. Again, this new fibrous structure contracts and shortens the valves, so that their parts cannot meet properly and prevent the re- flux of the blood. So blood from the ven- tricles sent into the great arteries will flow back again into the heart, to be forced out again by new contraction. This is insuf- ficiency, or regurgitative disease of a valve; The stiff, unyielding state, when it obstructs the current, is called obstructive disease of the valve (stenosis). The valves are thickened also by the deposit between their folds of a yellowish substance, made up partly of small microscopic cells, and partly of fat-globules, called atheroma, one of the products, it is be- 40 THE FAMILY PHYSICIAN. lieved, of a slow or chronic inflammatory action. In time this atheromatous deposit is apt to be converted into, or rather is re- placed by, a hard calcareous material, or even organized bone-structure. In the same way the least organizable portion of the de- posit of acute inflammation (endocarditis) may slowly be replaced by the same mate- rial. This is the ossification of the valves. It is not a very frequent occurrence, and is limited usually to a small portion of a valve. But it does mischief, partly as an obstacle to the blood-current, but more by irritating these movable folds and keeping up chronic inflammation in them, and causing thicken- ing, inflexibility, and shortening (just de- scribed), or increasing them if they have already occurred. Rupture of the valves is possible. The aortic valve may yield in the bottom of one of its cups; or the marginal thread may separate from the deeper part of the cup; or the upper attachments of the cups to tbe aorta may give way; or the anterior leaf of the mitral valve may be perforated; or one or more of its tendinous cords may be broken. These accidents usually occur after the ruptured part has been weakened by the deposit in it of a plate of atheroma; yet they may yield without previous disease, but then always at the time of great exer- tion of muscular strength in lifting weights, running, jumping the rope, or the like. The reader may remember to have seen a few years ago a newspaper statement that a girl about twelve years old had been serious- ly injured by jumping the rope nearly 200 times without stopping. It was ascertained in that case that there was rupture at the mitral valve, probably of some of its tendin- ous cords. Vegetations on the Valves.—This is another of the results of inflammation. They are minute hard warts that are formed on the free surface of the aortic valve just below its thickened margin. These are chiefly important as being the occasion of the deposit of masses of the fibrin of the blood upon the valves, so producing large granu- lar-looking warts, which obstruct the out- flow from the ventricle. . Any roughening of a valve-surface by inflammatory or other disease, or by rupture, may cause the de- posit of these fibrinous concretions. When they occur they not only obstruct the flow of the blood, and partially disable the valves, but portions of them may be wash- ed off into the arterial current, and be car- ried into a distant organ, as the brain, spleen, or kidney; and one of these reach- ing an artery too small to receive it, it stops there, and cuts off the arterial blood from all portions of the organ usually supplied by the obstructed vessel. This mode of plugging up the arteries is called embolism ; the plug itself is an embolus. In the advanced stages of these diseases of the valves and muscular structure it is not difficult to arrive at the opinion that there is heart disease. Shortness of breath, induced by exercise, the strong heart-beat- ing, beating of the vessels in the neck, and, when the kidneys become diseased, the dropsies, the distress produced by lying down, tell the truth but too certainly. But they do not designate the particular form or forms of disease. This can only be learned by listening to the sounds produced by the action of the heart, and by actual measurement by percussion. Thus, in ad- dition to the two natural sounds remaining, from one to four new ones may be produced, called murmurs. If there is a murmur heard most distinctly under the breast-bone, where the third ribs are joined to it, and while the ventricle is contracting (in sys- tole), it is probable that there is obstructive valvular disease, either in the aorta or pul- monary artery, and the chances are thirty to one that it is in the former, for in this proportion at least is valvular disease found more frequently on the left than on the right side. Indeed, the grave valvular dis- eases of the right heart are almost always found to have occurred before birth. The aortic-valve murmurs are heard distinctly at the junction of the third costal cartilage of the left side with the breast-bone, as is also the pulmonary murmur, which is rare. If there is a murmur with and after the second, heard most distinctly at the same place, it indicates insufficiency—that is, re- gurgitation, as already explained. It will be remembered that the two hearts contract simultaneously, and that the two second sounds are simultaneous. If, then, the sec- ond sound on one side is silenced by deform- ity of the valve, the valve on the other side is, in all probability, normal, and produces its own normal second sound strongly enough to be heard. A murmur heard most distinctly in the left and lower part of the heart-region (towards the apex) is referred to a diseased mitral valve. If it is in systole, the valve is insufficient, and there is regurgitation from the left ven- tricle into the left auricle. If it is in " the period of repose "—that is, the period between the second natural sound of the heart and the recurring first — it will in- dicate an obstruction, from stiffness or other diseased change in the valve, to the flow from auricle to ventricle, for it is in this period that the auricle is emptying itself into the ventricle. There is nothing in the tone or other characters of these mur- THE FAMILY PHYSICIAN. 41 murs which indicates the character of the valve-change, except that a musical mur- mur is sometimes produced by the string left when the thicker border of an aortic cup is split off from the membrane below it, or a similar cord may be formed by rup- ture of the mitral valve. This must be learned, if it can be learned at all, from the general history and symptoms of each par- ticular case. With two exceptions, these murmurs are positive indications of change in the form, thickness, dimensions, or structure of these halves. There may be an anaemic murmur with the ventricular contraction at the aortic opening when the blood is thin, or does not contain its normal quantity of animalized elements—or, in other words, when it con- tains too much water (hydroozmia and chlo- rosis)—and there may be actual regurgita- tion, and the corresponding murmur at the mitral valve, caused by the irregular or im- f>erfect contraction of fleshy columns of the eft ventricle. The same rules are applicable to valvular diseases of the right heart, except that the murmurs of the tricuspid valve are heard at the junction of the sternum and fourth right rib, and those of the pulmonary artery at the junction of the left third rib with the same bone. These are the common forms of heart dis- ease; and there will be in this article no better place than here to say that the pop- ular opinion of their fatality is erroneous. Few persons can hear the announcement that they have disease of the heart, of whatever kind, without hearing in it the command, "Set thine house in order, for thou shaft surely die," and the general expectation is that the death will be sudden. It is true that there are sudden deaths from heart dis- ease even in persons who have not been ill enough to consult a physician. But these sudden deaths are exceptions. For one such, a quarter of a hundred live on until death comes through some disease which could not have been looked for, or the kidneys become involved in secondary Bright's dis- ease, and perhaps become the chief actor in the concluding scene. The writer dis- covered in a young lady thirty-four years ago mitral regurgitation and decided hyper- trophy of the heart. Now she is the mother of seven children, and, as far as her friends can judge, is in perfect health, except that she has shortness of breath at times. He examined a gentleman sixty-five years of age who had obstructive aortic disease and hypertrophy, in whom he traced the origin of the affection back to an attack of rheu- matism when the patient was fifteen years old; yet this gentleman had had the energy to amass for himself a fortune of a million of dollars, and to build up the fortunes of two brothers; and that too in the good old times of honest industry. He knows physi- cians who carry considerable heart disease for indefinite years through an active prac- tice. He knew one, an old gentlemen, who had the disease nearly all his life, and con- tinued his professional work till within a few days of his death. His heart weighed after death two pounds three ounces and two drams. The former possessor of the heart which weighed 57 ounces, referred to in this article, became diseased when he was six years old, and he died at twenty- eight, having been active as foreman in a large cotton-mill till four weeks before his death; and even then death was caused more by the kidneys than by the heart. These are not rare instances, but represent the important fact that these diseases, even when extreme, do not generally cause death without aid from another important organ ; and when moderate in degree, if the avoid- able causes of their increase are avoided, have, till the age of sixty and upward, but little influence in shortening life, except, again, with the concurrence of other and dangerous diseases. Pericarditis.—As the lining membrane of the cavities is subject to inflammation, so is the external covering. This and the lining of the fibrous pericardium are alike liable. They are indeed but one membrane. Peri- carditis and endocarditis often occur at the same time, being both produced by an ex- tension or migration of articular rheumatism, or rather by that same state of the system which causes the articular disease. Either of these diseases may accompany Bright's disease. Beyond the concurrence with these affections the causes of pericarditis are not well defined. The disease itself, as well as endocarditis, has only been intelligently ob- served during the present century. The changes produced by pericarditis are, first, an increase in the quantity of blood in the vessels of the membrane; second, absorption of the fluid which in health diminishes the friction between the heart and pericardium; third, the discharge from the engorged blood- vessels of the fluid portion of the blood (liquor sanguinis) in condition to form new tissue, false membrane, or of the more watery parts, known as serum. Both of these prod- ucts of this inflammation are commonly found, but the serum is usually much the most abundant and the most oppressive. When there is little serous fluid the disease may run its course with but little general disturbance; but when the quantity is large there is a rapid pulse, oppressed breathing, and a tendency to faint when sitting or standing. The pericardium is distended by 42 THE FAMILY PHYSICIAN. its watery contents, sometimes even to ten- sion ; then the normal dilatation of the heart-cavities becomes difficult. But this fluid is absorbed usually in about a week, and the pericardium comes back to its con- tact with the heart. The common opinion regarding the fibrinous coating produced by inflammation is that it receives blood-vessels, and remains for a time the medium of the union which almost always takes place be- tween the pericardium and the heart, after pericarditis; but according to some late German teachings it readily breaks up into granular and fatty matter, and is carried away by absorption; and they account for the adhesion by stating that the serous mem- brane is roughened during the inflammatory process by the production on its surface of many little granules or warts composed of fibrin, and that these mutually grow into the opposite surface, and so cause a blend- ing. There is produced by the dry condition of the membrane, caused by the first en- gorgement of the vessels, a distinct creaking or rubbing noise as the heart moves in the pericardium—a "to-and-fro" sound, in time with the pulse. This sound is renewed when the fibrinous exudation takes place, heard first in systole, and soon after in both con- traction and expansion of the heart. This may be interrupted when the serous effusion lifts the pericardium off from the heart, to be renewed again when the serum is ab- sorbed and contact is renewed. The adhe- sion above spoken of takes place soon after the renewal of contact, so that in this re- currence the friction-sound does not com- monly continue for more than a day. When the area of dulness on percussion is rapidly extended to the left of the heart and above the third rib, and this extension follows the friction-sound, it is produced by the serous effusion. The heart-sounds under these cir- cumstances become a little less distinct as the heart is buried in water. This is the condition indicated by the phrase "water on the heart," popularly supposed to be a common malady, but it is not found to exist in one in twenty of the cases in which it is suspected. Pus is not often found in the pericardium after inflammation. In chronic pericarditis, implying chronic distension of the heart-sac, the fluid causing the disten- sion is partly pus (sero-purulent). Chronic pericarditis is a grave disease; it is almost always fatal. In it the pericardium, in one case treated by the writer, was found to con- tain a gallon of sero-purulent fluid. Acute pericarditis is rarely fatal in the first attack. But in young persons subject to recurring rheumatism each return is more and more dangerous; even the third is not unfre- quently fatal. Pneumo-pericardium (air or gaseous matter in the pericardium).—A man amid the hor- rors of delirium tremens had a plate on which two teeth were set detached from his mouth, and he tried to swallow it, but it was stopped in the oesophagus (gullet) at a point just behind the heart. A projecting angle of the plate pierced the walls of the oesophagus and pericardium, and opened a passage by which the food and drink pass- ed directly into the latter. Air also entered the pericardial sac. With each contraction of the heart there was a splashing noise, such as is produced by the agitation of a bottle containing air and water. Cancerous disease sometimes produces a similar open- ing. Gaseous matter of some sort—perhaps carbonic acid gas—is in rare instances lib- erated in this sac, and, so far as is known to the writer, there is always fluid in the cavity at the same time. The splashing in con- traction of the heart is heard even a few inches from the body. The signs of this kind of pneumo-pericardium pass away as the signs of the pericarditis which it accom- panies disappear. The perforation of the pericardium with admission of air is almost always fatal, while the elimination of gas in the cavity is not generally attended with serious consequences. Carditis, or myocarditis, is an inflammation of the muscular structure of the heart. It is an occasional attendant of endocarditis or pe- ricarditis, or may occur independently. The symptoms are vague and uncertain, so that it is difficult, and often impossible, to recog- nize it during life. It is, then, chiefly known by certain conditions found after death. In limited portions of the left ventricle, or in the septum of the ventricles, the muscular fibres are broken up into fatty matter and fine granules, forming what is commonly called an abscess; indeed, real abscesses are seen when the cause of the carditis is septi- caemia (poisoning of the blood by decompos- ing animal matter), as in gangrene of the lungs. But what is more frequently met with is a cicatrix, one or more, showing that while the muscular element is broken down, its fibrous covering (perimysium) has in- creased in quantity, and forms a depressed cicatrix, the pyoid matter having been ab- sorbed and carried away. These cicatrices do not always restore the strength of the structure they replace. Hence, they some- times yield gradually, producing aneurism of the heart. Such is the current view of myocarditis, but the writer gravely doubts whether this kind of fatty degeneration of the cardiac muscle is the result of full in- flammatory action. The muscular fibres of the heart sometimes undergo a fatty degeneration, in which, with- THE FAMILY PHYSICIAN. 43 out change of size or change in the valves, little globules of oil have replaced the mus- cular substance. This degeneration weakens the heart, and causes it to act irregularly, changes its color from dark red to yellow' and materially diminishes its firmness. The disease is named, after the English surgeon who first described it, Quain's degeneration, or, better, Quain's disease. The same gentle- man has recently announced that there is an hypertrophy of the heart, which is caused by an increase of the fibrous structures of the organ, while the muscular elements remain unchanged. The admission of the existence of such a disease awaits further investigation. Should the observation be verified, we shall have to admit into medical nomenclature Quoin's hypertrophy. Fatty heart has long had a significance very different from that of " Quain's disease." There is always on the outer surface of the heart a limited amount of what is called adipose tissue, or, in common language, "fat." This tissue is composed of layers of cells almost large enough to be seen by the un- assisted eye, each having one or more capil- lary blood-vessels passing over and nearly around it. These cells contain oil, the quan- tity of which is large when a person is said to be "fat," or they are empty and small when he is pronounced to be " lean." This tis- sue is found under the skin in many parts of the body, but not in all, and in considerable quantity in the abdominal cavity. The por- tion of it that naturally belongs to the heart is small, and lies outside the muscular struc- ture, and within its external serous invest- ment (serous pericardium). The quantity of this is sometimes dangerously increased. It increases always at the expense of the muscle of the organ, so that the muscular wall be- comes thin at certain places; and as the adipose tissue has not the strength of mus- cular, which it has displaced, the heart-wall is weakened where it is most increased. The undiminished strength of the other portions of the wall of the same cavity will sometimes cause this weaker part to give way. Rupture of the heart occurs in the manner just described. It may occur also when the wall of either ventricle is weakened in one part only or principally. This may be the effect of a local development of Quain's dis- ease ; of an ulcer caused by the deposit of atheromatous matter on the outer surface, and its subsequent softening; of abscess and pseudo-abscess resulting from myocarditis, as above described; or from aneurism of the heart, in which an external tumor is formed by the internal pressure of the blood and the gradual yielding of a limited portion of the wall. Tli ere is then really a broken heart. When this rupture occurs, the blood pours through it, and soon fills the pericardial sac, and the heart-dilations are prevented. Such a sudden death is preceded by few symptoms, and sometimes by none. This occurrence is, however, rare. When it results from adipose degeneration, it is commonly found in the right ventricle; when from other causes of local weakness, it is usually found in the left. Heart- Clot.—-In rare instances the blood coagulates in the heart before death. This coagulation may be the cause of death, or the subject of it may survive for years. It may occur in the left ventricle, where it may be an inch or more in diameter, but being attached to the raised cross-muscles of this cavity, it does not obstruct the passage of the blood into the aorta. The fibrin which constitutes this mass is arranged in layers, and in most of the few instances that have been seen the central portion had already broken down into a yellowish fluid, which has been erroneously'taken for pus. Clots and fibrinous aggregations, formed in the heart-cavities during life, may be the cause of death, either suddenly.or remotely. The clots found after death usually fill one or more of the cavities, and are attached to the cavity-wall in all its circuit, or they are di- vided into two parts—one yellow or yellow- ish-white, glistening, and not wholly opaque; the other very dark, almost black. In hun- dreds of instances such coagulations as these have been regarded as ante-mortem clots, and the immediate cause of death. If a clot is formed before death, the heart must con- tract upon it at least once. One such con- traction is sure to separate it from its adhe- sion through a considerable portion of its circumference. The production of the light- yellow clot is only possible when the blood has been at rest long enough to allow its red corpuscles to sink in the fluid as far as this buffy portion extends; and the reason for its forming so considerable a portion of the whole coagulum is that the blood does not usually coagulate in the body till about six hours after death. Embolism and Thrombosis of the Coronary Arteries of the Heart.—The first of these terms refers to the fact that clot or fibrinous concretion may form in the heart, as already explained, and that a part or the whole of it may be detached and carried forward till it reaches an arterial division too small to receive it; it cannot go back, but must re- main there, preventing the circulation of arterial blood in the artery beyond it, till it is disintegrated and carried away. It is pos- sible that a portion of a fibrinous concre- tion on the valves or wall of the left ven- tricle, so detached, may enter one of the coronary arteries, and so obstruct it. But a section of the aortic valve covers the mouth 44 THE FAMILY PHYSICIAN. of each of these vessels during the contrac- tion of the ventricle, and they receive their blood in the reflux, after the closure of the valve; and the force that propels it is the elasticity of the aorta. This protected con- dition must render such an accident very rare. What we are more familiar with is thrombosis, or the coagulation of blood in the artery. This cuts off half of the supply of blood to the heart; a pretty rapidly in- creasing feebleness of the heart-action fol- lows, with a weak and slow pulse, great prostration of strength, extreme paleness of countenance, coldness of the feet and hands, and after these symptoms death occurs in ten to twenty hours in the ma- jority of the cases. Angina pectoris (breast-pang). See An- gina Pectoris. Deformities and Defects.—The growth of the heart may be arrested in any of the stages of foetal life. The most common of these defects is an open foramen ovale, permit- ting venous blood from the right auricle to mingle with the arterial in the left. This is produced when the current through the pul- monary artery is obstructed. This state of the heart is known as morbus cozruleus, or blue disease. The name, however, applies equally to other congenital defects that per- mit venous blood to pass into the left heart or into the aorta to circulate in the arteries, producing blueness of the skin. This color is not constant, except in a few, but is pro- duced by crying, a fit of coughing, excite- ment, or unusual physical exertion. It is not incompatible with a life of limited dura- tion, but is likely to be attended by dimin- ished growth of body, bodily and mental sluggishness, shortness of breath, palpita- tion at times, and occasional fainting. If the subject of any of these defects survive the first years of life, the defect alone will not probably be the immediate cause of death, but it will diminish the power of resisting a fever, a pneumonia, or any grave disease, and especially one that disturbs the balance of the two circulations. Less than ^ (4 per cent.) of all deaths are caused by all these agencies put to- gether; a very large proportion of the deaths so occurring are in persons of ad- vanced age; even when disease fastens on the heart, it does not, as a rule, preclude the hope and expectation of "length of days;" and counting, from youth to age, not one in a hundred persons has any kind of disease or defect of the heart. (See also articles a^x.emia, PaVLPITATion.) Hec/tic Fever [Gr. inrudg, from kljig, "habit"], a fever which is so continued as to constitute a habit (s^ig) of the body. Such fevers are probably always symptom- atic of some local or extended irritation. Thus, hectic attends pulmonary consump- tion, chronic pleurisy with extensive exuda- tions, peripheral caries of the bones, etc. Hectic, as it occurs in pulmonary consump- tion, is sometimes intermittent, with even- ing exacerbations; sometimes almost con- stant. The latter kind generally affords a bad augury, and it cannot in general be much relieved by treatment; but intermit- tent hectic may often be palliated, greatly to the patient's relief. Remedies are there- fore directed against the primary disease. Hemiplegia [from the Gr. y/ui-, "half," and nAriyr], a "stroke"], that kind of paral- ysis which affects only one side of the body; or if both sides are affected, it is from the occurrence, a very rare one, of double hemiplegia—that is, of two concurrent par- alytic strokes, one affecting each side. It manifests itself usually in the upper and lower extremities of one side, and in the parts of the head which are supplied by the fifth nerve. It may be the result of an apoplectic stroke, or of a slow effusion, or of the growth of a tumor within the brain. Owing to the decussation of the pyramids, the paralysis takes place usually on the side of the body opposite to the side of the brain in which the lesion has occurred. For ex- ample, if there be a tumor growing in the left hemisphere of the brain, the paralysis will, as a rule, be manifested in the right side of the body, because the nerve-fibres cross over from side to side near the base of the brain. But if the lesion occur below this crossing, there may be hemiplegia on the same side. Hemiplegia affects chiefly the nerves of motion, but affects more or less those of sensation also. Temporary attacks of hemiplegia are also observed in chorea, epilepsy, and hysteria. The treat- ment of hemiplegia varies with the condi- tion of the patient and the cause of the stroke. Generally, time and rest are im- portant to the relief of the patient. HepatFtis [Gr. yirap, the "liver"], an inflammation of the liver. Hepatitis is not a very common disease in any country. Several kinds are recognized: (1) Suppura- tive hepatitis, or abscess of the liver, some- times occurring in India, but rare in other countries. (2) Interstitial hepatitis, called, rather incorrectly, cirrhosis, known also as granular liver and gin-drinker's liver. It is incurable, and is probably always caused by the improper use of alcoholic drinks. It frequently leads to ascites or abdominal dropsy. (3) Portal phlebitis, or inflamma- tion of the portal vein, may occur. (4) Inflammatory disease of the liver is some- times a syphilitic complication. Each of the above-named conditions is a grave one, THE FAMILY PHYSICIAN. 4") and in few cases can treatment be of much avail. Her/nia [Lat.], the protrusion of a viscus from the cavity to which it normally be- longs ; but the term is generally used to express the protrusion of an abdominal vis- cus, as when we speak of other forms of hernia we express it thus: hernia cerebri, hernia corneae, etc. The predisposing cause of hernia is a weakness of some portion of the abdominal walls, and there are certain parts which are naturally weaker than others, as the inguinal, umbilical, and fem- oral regions. This weakness very often exists congenitally, and may be increased or produced by injury, disease, or pregnancy. Among the exciting causes may be men- tioned violent muscular exertion, jumping, straining from lifting heavy weights or at stool, playing on wind instruments, etc. The usual contents of a hernial sac is a por- tion of the small intestine or the omentum, but we may find portions of any of the vis- cera in it, especially when the abdominal walls are congenitally weak. The sac is formed of peritoneum, which is covered by the integument and subjacent fasciae. Hernia is generally divided in two ways : lst,according to its situation, as inguinal, fem- oral, umbilical, diaphragmatic; 2d, accord- ing to the condition of the protruded viscus, as reducible, irreducible, and strangulated. Reducible hernia is that variety in which the contents of the sac may be returned into its normal cavity without recourse to a sur- gical operation. It sometimes disappears spontaneously when the patient seeks the recumbent position, but more often needs a greater or less amount of pressure to be made in the proper direction. The reduc- tion is facilitated by raising the foot of the bed in which the patient reclines, and by the inhalation of ether or chloroform. The symptoms of it are—the appearance of a soft and compressible swelling at some por- tion of the abdominal wall, which increases when the patient stands up and diminishes when he lies down; by placing the hand upon the tumor and directing the patient to cough a distinct impulse is imparted. The treatment usually adopted consists of the reduction of the contents, and the appli- cation of a suitable truss to prevent the re- protrusion. If the patient is young, this method will effect a radical cure in time, but in the adult recourse must be had to an operation to effect this. Irreducible hernia differs from reducible in that the protruded viscus cannot be re- turned into its normal cavity. The general causes of it are adhesions between the sac and its contents, the growth of membranous bands across the sac, or enlargement of the contents. It is much more troublesome than the preceding variety; in the first place, it is much more inconvenient, and is always exposed to the danger of strangulation ; the patient suffers from indigestion, constipation, colic, flatulence, and dragging pains in the loins. The treatment of this variety must be generally palliative, and consists of the patient's avoidance of all violent exercise; regulation of the bowels, which should never be allowed to become confined; and the wearing of a truss to support and pro- tect the tumor. " Hernia is said to be strangulated when it is constricted in such a way that the con- tents of the protruded bowel cannot be pro- pelled onward, and the return of its venous blood is impeded." There is always more or less inflammation, caused by the con- striction. The causes of this condition are sudden enlargement of the contents of the sac by faeces or gas, or congestion or swell- ing of the neck of the sac. The symptoms are—pain, flatulence, a desire to go to stool, constipation, nausea, and vomiting, the vomited matter after a time becoming ster- coraceous. The tumor is hard, and cannot be replaced in the abdominal cavity, and there is very little impulse transmitted to the hand when the patient coughs. The pain in the tumor continues to increase, and extends over the whole of the abdo- men ; the countenance assumes an anxious expression ; the pulse becomes small and wiry, and the skin cold and clammy. Should the pain cease, and the tumor feel doughy and crepitate when handled, we may be sure that the intestine has mortified ; when this happens there is very little hope for the patient; in fact, the only chance for recov- ery now is by an artificial anus. The object of treatment is to return the intestine into its cavity. When this cannot be accom- plished by manipulation, or manipulation combined with warm baths and the admin- istration of ether—the patient having first been placed in such a position that all the parts in the neighborhood of the trouble shall be completely relaxed—recourse must immediately be had to an operation. This consists in enlarging the constricted por- tion, so as to allow of the return of the gut. It is done by cutting down to the sac, and either opening it and dividing the stricture, or dividing the stricture without opening the sac, or by merely incising the neck of the sac. Her'pes [from the Gr. kpnu, to "creep"], a name applied to several skin diseases, cha- racterized by the development of a series of vesicles or clusters of vesicles, which general- ly run a definite, self-limited course. By far the most important of these diseases is Her- 46 THE FAMILY PHYSICIAN. pes zoster, zona, or " shingles," as it is called. This may surround one thigh or one arm with a band of vesicles, or more frequently it starts from the backbone and follows an intercostal space half round the body. More rarely it goes half round the neck or half across the face. There is usually some neur- algic pain, and sometimes considerable fe- ver. The disease must depend upon some abnormality in the nervous action, as it fre- quently maps out upon the surface the part of the integument supplied by some one branch of a nerve. The vulgar have a great dread of "the shingles," and believe that when it so extends as to completely girdle the patient he will die. But, in the first place, it almost never does go more than half way around the body, and, what is more, there would be no danger if it should, for the disease is a self-limited or cyclical one, and the patient is sure to get well if let alone. Other forms of so-called herpes, such as H. circinatus, are caused by parasitic veg- etation, and should be treated with applica- tions of sulphurous acid and water or other parasiticide agents. Hic'cough, or Hic'cup [Lat. singultus], a clonic spasm of the diaphragm and of the glottis accompanied by a sharp sound, pro- duced by the rush of air into the larynx from without. It may attend an over-dis- tension of the stomach with food, and some- times accompanies intoxication. In young children it often is the forerunner of intes- tinal disturbances. When persistent, it is, in some diseases, such as low fevers, perito- nitis, and gangrene, a rather grave symptom. Lumps of ice frequently swallowed or small doses of antispasmodic medicines will usual- ly relieve obstinate hiccough. Hip-joint, Diseases of. See Coxalgia. Hives. See Nettle Rash. Hooping Cough. See Whooping Cough. House'maid's Knee (so called because it is said, though with little reason, to be most common among housemaids, who scrub stairs and floors upon their knees), an acute or chronic dropsical effusion into the bursa be- fore the knee-pan. It is easily diagnosti- cated, and does not communicate with the knee-joint proper. Acute cases may be cured by rest and the application of iodine, mercurials, and tight bandages; chronic ones, by compression with suitable splints, or even by evacuation and injection of iodine solution into the sac. HydaFid, a morbid growth characterized by the development of a cyst, which contains an aqueous and transparent fluid, in which floats a parasitic worm, generally the acepha- locyst. The term was formerly used to desig- nate any encysted tumor containing a trans- parent liquid, but is" now restricted to that form which encloses a parasite. The organs most commonly affected by this peculiar dis- ease are the uterus, ovaries, and liver; next frequently we find it in the breast and testi- cles, but rarely in other parts of the body. It generally appears as a round hard tumor, which occasions more or less pain and in- convenience ; this tumor is made up of hy- datids, although we sometimes have it occur- ring singly, when it will be proportionately large. Each parasite consists of a body and head; around the latter we find a row of teeth which are hook-like and sharp. The body is solid, and displays a number of ovoid bodies beneath its coat, which give it a speckled appearance. As the tumor in- creases in size, if it is near the surface, we can feel fluctuation; the pressure under the skin causes it to ulcerate, and the hydatids may thus perish. If they are situated in some internal organ, they may produce very serious complications, as peritonitis, osteitis, etc. The treatment consists in excision if they are sufficiently superficial, otherwise we can do nothing. Hydrocele [Lat. hydrocele; Gr. bdpoia'ftw, from Mup, "water," and afar/, " tumor"], an accumulation of water between the two serous coverings of the testicles or of the spermatic cord, known as the tunica vagina- lis. It may follow an inflammation of the testes, but generally follows strains. It may affect both sides at the same time, but usually we find the effusion on one side only. It forms a pear-shaped, painless tumor, which causes uneasiness to the patient only on ac- count of its size; it sometimes grows so large as to reach nearly down to the knees. Unless the sac in which the fluid is enclosed be abnormally thick and distended to its ut- most by the contained fluid, fluctuation can be felt. There is no impulse felt upon coughing. By stretching the integuments over the tumor, and placing a candle behind it in a dark room, the light will be trans- mitted ; this would not occur if the swelling were solid. Another test to determine the consistence of it is to plunge a needle into the mass, and see whether it falls over to one side and floats about, or retains the po- sition in which it was placed. The treat- ment of hydrocele may be divided into the palliative and the radical. The former con- sists in drawing off the effused fluid by the trocar and canula ; this relieves the patient for a longer or shorter time, but the sac is apt to fill again, when the operation has to be repeated. We find patients submitting to this operation from once to four times an- nually throughout their lives, rather than submit to a procedure which is perfectly harmless and would ensure their complete recovery. The radical cure is effected by THE FAMILY exciting an inflammation in the sac which shall cause the opposing surfaces to adhere, and thus obliterate the cavity and prevent further effusion. This is sometimes accom- plished by irritating the surfaces with the end of the canula before it is withdrawn, but this method is uncertain. Generally, it is done by injecting some stimulating fluid; for this it was customary to use port wine or zinc lotion, but more recently tincture of iodine seems to be the favorite. If there is much inflammation, cold applications locally and opium internally are the indications. Hydrocephalus [Gr. vSpoKE^alov, from v6up, "water," and KscpaAy, "head"], a drop- sical effusion of fluids into the interior of the skull, occupying one or more of the ven- tricles of the brain or the sub-meningeal space, or both. Acute hydrocephalus is ordinarily a symptom of Meningitis (which see), particularly of tubercular meningitis; but cases occur in which no tubercle can be discovered after death. The causes of chronic hydrocephalus are various. It is regarded as certain that arrest of development of the brain-substance, pressure upon the veins of Galen by masses of tubercle or cancer, and in fact any condition which obstructs the venous circulation in the brain, may lead to hydrocephalic effusion. The large majority of cases are congenital, and hydrocephalus must be set down as a disease (or symptom) belonging to infantile life; but cases occa- sionally occur in mature life or in old age. Dean Swift, after three years of illness, died with hydrocephalus, the result, doubtless, of organic brain-disease. The prognosis of chronic hydrocephalus is very grave. The child may live for many years, but (with rare exceptions) becomes idiotic, and in some cases is epileptic. The head becomes distended, the fontanels remain open, ossa triquetra form in the courses of the cranial sutures, and in some cases quarts of fluid are effused, consisting of water, with earthy salts and a little albumen; while in acute hydro- cephalus there is sometimes much albumen present, with some pus-corpuscles or a little blood. When the disease is detected early, mercurial inunctions, with the administra- tion of the iodides, may possibly afford bene- fit. Treatment by systematic compression or by tapping the skull (the latter operation to be followed by firm compression) has been tried in many cases, but the most common result has been the speedy death of the pa- tient, although in a few instances it would appear that more or less advantage has been obtained by these means. The term spurious hydrocephalus is sometimes applied to infan- tile typhoid or other enteric disease, the general symptoms of which may simulate those of acute meningitis. PHYSICIAN. 47 Hydrophobia (syns. Rabies, Rabies cani- na, Rabies contagiosa), [from the Greek Mop, "water," and $6jlog, "fear"] is a re- markable disease to which both the human species and probably all of the brute crea- tion are subject. We can discover only rare allusions to it previous to the Christian era. Such references, however, are sufficient to indicate that, although it may not have been so prevalent among the nations of antiquity as among those of more modern periods, yet it was in very ancient times recognized as a peculiar disorder infesting certain animals, and even man himself. There are two passages in Hippocrates which appear to indicate that he had ob- served its characteristic symptoms in man, but failed to regard it otherwise than as a variety of idiopathic phrenitis. His con- temporary, Democritus, however, who was a famous traveller, had probably encounter- ed the disease in foreign regions, as he was evidently well acquainted with its most striking peculiarities. We are informed by the distinguished physician Coelius Aure- lianus that Democritus, in a treatise upon opisthotonos, had described the affection in the human subject, admitting its origin from the bite of rabid animals, but considering it simply as a form of tetanus. Theocritus and Plato refer to madness among wolves. Aristotle, in his History of Animals, remarks that dogs are afflicted with madness, quinsy, and gout; that the first renders them furi- ous and inclined to bite other animals, which thereupon also become rabid; and that all animals except man are liable to be seized with and destroyed by the malady so engendered. In the early portion of the Christian era the allusions to this affection become more frequent. Virgil, in his Georgics, classes rabies among the distempers of cattle and sheep induced by a pestilential condition of the atmosphere. Ovid speaks of a rabid she-wolf and rabid centaurs (rabidi Bimem- bres), and Pliny of the bite of a mad dog. Horace employs the expression rabies canis. The disease is mentioned by Columella, a writer on husbandry in the first century, who alludes to an opinion common among shepherds that a dog may be ensured against rabies by biting off the last bone of its tail on the fortieth day after birth. This is still a popular superstition. Suetonius refers to wild animals affected with mad- ness (fera rabida). Dioscorides, in the time of Nero, appears to be the first who claims to have actually observed and treated the disease. Both he and Galen describe it as attacking animals and men, and agree in the opinion of its communicability from the former to the latter by contact of morbid 48 THE FAMILY PHYSICIAN. saliva with the second skin. But Galen, and Celsus as well, concern themselves rather with the prevention and treatment of hydrophobia than with its history and progress. AVccording to Plutarch, it was not until the time of Pompey the Great that the rabific poison first began to manifest itself among human beings. Coelius Aurelianus is the first to furnish an accurate detailed description of the affection in man, and of the various controversies regarding it. He called it passio hydrophobica. vEtius, a Mesopotamian doctor of the sixth century, is the first to furnish anything like an ac- curate description of rabies in dogs. A century later the physician Paulus JEgineta gives an excellent account of hydrophobia, dividing it into two varieties—viz. that aris- ing from inoculation, always fatal, and that due to nervous irritability, capable of cure. A similar distinction is now sometimes made, particularly by French authors. Rhazes affirms that a certain hydrophobic man barked by night like a dog and died, and that another when he beheld water was seized with trembling, extreme terror, and rigors. Avicenna, at the commencement of the eleventh century, describes hydropho- bia with considerable fulness, noticing several of its phenomena ignored by the Greek and Roman authors. He terms it simply canis rabidi morsus. In 102(5 an out- break of rabies among dogs is mentioned in the laws of Howel the Good. From that time it appears to have been well known in England, numerous specific remedies, charms, and incantations against it being recommended in old Anglo-Saxon manu- scripts still extant. On the continent of Europe the modern history of rabies is ob- scure until the thirteenth century. One of the earliest reports of scientific interest refers to wolves afflicted with the disease in Franconia, Germany, in 1271, where more than thirty shepherds and peasants fell vic- tims to their attacks. Since that period we find frequent mention of the affection as prevailing in an epizootic form in almost every country of Europe, but more particu- larly in the wooded districts of Germany, Switzerland, and France, appearing to at- tack principally wolves, dogs, and foxes. Vulpine madness, however, was not noticed until the beginning of the present century in Europe, although it had appeared in the neighborhood of Boston, U. S., in 1768. In 1770 rabies made its first appearance in the French West Indies, and in 1785 it became | extremely prevalent throughout the IT. S., and since that time the disease in both ani- mals and men has occupied a prominent lace in our medical literature. In Asia its istory, as we have seen, is very ancient. It has never appeared in Australia or New Zealand. The popular belief that hydrophobia is in all animals characterized by an abhorrence of icater was long since proved to be erro- neous. The mad dog laps it eagerly, and will not hesitate to swim in it when it obstructs his course. In the ease of man, however, the attempt to drink, or whatever is suggest- ive in any manner of that act, induces such dreadful spasms of the muscles of degluti- tion and respiration, with sense of suffoca- tion, that a horror of fluids, even though associated with intolerable thirst, may be truly regarded as one of the most promi- nent and characteristic features of the dis- ease. For these reasons a distinct term, rabies, has been employed by some writers to designate this affection as it prevails among the brute creation, the word hydro- phobia being restricted to the disorder as manifested in man. It is almost universally conceded that the introduction of a specific virus, from a rabid animal, into the system, through either an ac- tual wound, an abraded surface, or a delicate mucous membrane, is an essential preliminary to the development of this affection in man. But its origin among brutes has always been, and still is, a subject of much dis- cussion. Hydrophobia certainly infests, and by many is regarded as originating de novo among, certain Carnivora—viz. the dog, wolf, jackal, cat, skunk, and raccoon—while her- bivorous and other creatures, including man, contract it by inoculation alone. Of the various conditions asserted as favoring its spontaneous development in the canine race, few have even a probable foundation. They are principally repressed sexual desire, ex- tremes of atmospheric temperature, excite- ment of anger, want of water, and putrid or insufficient food. Still another presumed influence is the presence under the dog's tongue of a worm-like appendage, whose extirpation in puppyhood is considered an infallible preventive of the disease. This idea may doubtless be referred to a very ancient myth. Pliny speaks of it, terming the peculiar appendage lyssa. The Germans term it Tollwurm, or worm of madness, and among them it has long been a popular su- perstition. The practice of removing this so-called worm still exists in Thrace, Tur- key, Greece, Roumania, Moldo-Wallachia, Spain, and even in the Southern U. S. Its efficacy has been entirely disproved by sci- entific investigation, and the operation may be best characterized, in the expressive lan- guage of Dr. Johnson, as "a substance- nobody knows what, extracted—nobody knows why." The other presumed causes of spontaneous hydrophobia would appear THE FAMILY PHYSICIAN. 49 to be equally equivocal. Unsatisfied sala- city, putrid food, hunger, thirst, anger, and extremes of temperature are manifestly cir- cumstances which obtain among dogs quite generally throughout the world. But in some regions abounding in dogs hydropho- bia has always, so far as can be learned, been either totally unknown or extremely rare, while in others exempt from it for ages it has only recently appeared, and in most instances can be traced positively to importation. Such exemption has been par- ticularly noticed in various islands through- out the world and in isolated localities. It is related that Mr. Meynell, the most emin- ent English sportsman of the last century, preserved his kennel of hounds from hydro- phobia during many years by forcing every new dog to undergo a rigid quarantine of several months preparatory to his admission into the pack. Rabies canina prevails indifferently in all seasons. It seems quite well established that all creatures liable to contract the disease are also in a greater or less degree competent to transmit it, and we know of no animals ex- empt from it. It is true that herbivorous and ruminating beasts, owing to the forma- tion of their jaws and teeth, as well as to their seldom attempting to bite when rabid (sheep only excepted), rarely communicate the disease; and hence the belief, enter- tained for some time by such eminent men as Sir Astley Cooper and the veterinary professors Coleman and Renault, that the power to propagate the affection was con- fined to such animals as naturally employ their teeth for weapons of offence. The fallacy of this opinion has been proved by numerous unquestionable experiments, and it is now likewise conceded by the best au- thorities that the saliva of a hydrophobic human being is capable of inoculating the disease. The dog affords us the most frequent op- portunities for observing the phenomena of this redoubtable affection. Hydrophobia in the dog has been by some writers divided into two varieties, dumb and furious rabies, according as the animal is silent and un- demonstrative or noisy and fierce. Other authors recognize still a third variety, which they term tranquil rabies, where the animal is quiet, indifferent, and unaggres- sive. Virchow considers the different forms merely as prolonged conditions or stages, which, according to him, are—1st, the stage of melancholy; 2d, the irritable and furious; 3d, the paralytic stage. The disposition to bite is not apt to be exhibited until the af- fection is well established. The disease is first manifested by constant restlessness, un- easiness, and irritability of temper, the dog 4 of fondling or sociable disposition becom- ing snarly, morose, and shy, retiring under pieces of furniture, into dark corners, or the interior of its kennel, but not remain- ing long in any one spot, and being contin- ually engaged in licking, scratching, or rubbing some portion of its body. Costive- ness and vomiting are often present. The appetite becomes depraved. The counte- nance undergoes a marked change—assumes an appealing expression or becomes the very picture of ferocity. In the early stages the animal's attachment for its master appears greatly exaggerated, and as long as it re- tains its consciousness it will refrain from injuring him. Two early and characteristic signs of rabies are a peculiar delirium, causing the animal to snap at imaginary objects in the air, and a remarkable alter- ation in its voice, the bark ending very abruptly and singularly in a howl a fifth, sixth, or eighth higher than at the com- mencement. Sometimes it will utter a hoarse inward bark, rising slightly in tone at the close. Common symptoms are stra- bismus and twitchings of the face. In a couple of days the animal begins tp lose control of its voluntary muscles and ex- periences difficulty in eating and drinking. In the early stages frothy spume or slaver is generally seen dripping from its jaws, but this soon lessens in quantity and be- comes thick and glutinous, adhering to the corners of the mouth and fauces, and caus- ing intense desire to drink. It is now in- sensible to pain—will munch burning coals or even mutilate itself without apparent suffering. It exhibits an inclination to es- cape from home, to which it will sometimes return after many hours of absence. It is restless and savage, wandering about, at- tacking imaginary objects or venting its fury upon real ones. If confined, it gives utterance to the peculiar bark and howl described. When at large, however, it gives forth no warning noise, but seems only de- termined upon a straightforward trot. If interfered with, and more especially if struck, it will wreak its vengeance on the offender, but will seldom, as a rule, go out of its way to do a mischief, and if pursued will generally endeavor to escape. It does not continue its progress long, but becomes exhausted, and moves with unsteady, totter- ing gait, drooping tail, head toward the ground, mouth open, and protruded tongue of a lead-blue color; finally, paralysis en- sues, first of the hind quarters and then of the whole body, which is promptly followed by death. Its duration rarely exceeds ten days ; the ordinary time is from four to six days. Nothing has been positively deter- mined with regard to the interval elapsing 50 THE FAMILY PHYSICIAN. between the receipt of the injury and the appearance of rabies in the dog and other animals. It seldom, however, exceeds six months. Hydrophobia in our own species possesses a deep and melancholy interest on account of the peculiarity of its mysterious and often prolonged latency, the horrible in- tensity of its paroxysms, and its irresistible fatality. The virus of the rabid animal, when once its insidious operation has begun, defies the most consummate therapeutical skill. When the rabific poison has been deposited within the body no extraordinary appearances succeed about the point of re- ception, which seems to heal and cicatrize entirely in a natural manner. At that spot, however, the virus remains perdu until at some uncertain period it comes forth stealth- ily upon its deadly errand. The duration of this latency is no less variable in man than in the lower animals. According to Thamhayn's statistics of 220 cases of hydro- phobia in the human subject (in Schmidt's Jahrb'ucher, 1859), the period of incubation in 202 instances ranged from three days to six months. In 145, or the large majority, it extended to from four to thirteen weeks. One occurred after four years, and another after five and a half years. One of the earliest symptoms is usually a tingling sensation at the cicatrix, which sometimes opens and discharges a thin ichor- ous fluid. In a short time the person grows dejected, morose, taciturn, restless, and ir- ritable ; he seeks solitude and shuns bright and sudden light. Within a period varying from a few hours to several days the more serious and characteristic symptoms are de- veloped. The patient is sensible of a stiff- ness or tightness about the throat, and is troubled with some difficulty of swallowing, especially liquids. Deglutition soon becomes impossible unless attempted with the utmost resolution. The real paroxysms of the dis- ease then supervene: they are either spon- taneous or produced by anything suggestive in the slightest degree of the idea of drink- ing ; they are preceded by chills and tremors. During these attacks sensations of stricture about the throat and chest are experienced; the respiration is painful and embarrassed, and interrupted with sighs and sobs; in fact, there occur terribly violent spasms of the muscles of the throat, almost intercepting the entrance of air into the trachea. In the intervals between the paroxysms the pa- tient is sometimes calm and collected, retain- ing full consciousness and knowledge of his condition, but generally he exhibits more or less excitement and irregularity, and oc- casionally has fits like those of insanity. Frequently he is seized with a species of delirium; he seems to see about him swarms of flies ; he converses with imaginary per- sons or fancies himself in the midst of perils. When suddenly addressed, however, his hal- lucinations are for a time dispelled. Occa- sionally, in some of his fits of violence he will attempt to bite his attendants, will roar, howl, curse, and endeavor to destroy anything in his reach. He often seems con- scious of the approach of such attacks, and will beg to be restrained. Hyperaesthesia of the skin and acute sensibility of the nerves distributed to the other organs of the senses are usual. A very characteristic symptom is the copious secretion of a viscid, tenacious mucus in the fauces, which the patient con- stantly hawks up and spits out with vehe- mence in every direction, producing a sound sometimes imagined to resemble a dog's bark. The tongue is at first coated and red, afterwards dry and brown. Occasionally there is vomiting of a " coffee-ground" fluid. The pulse is quick and excited, becoming very frequent and feeble before death. The urine is high-colored and scanty. It gen- erally contains albumen, sometimes sugar. The temperature of the body is always ele- vated, which is coincident with rapid waste of tissue. Often within a few hours a plump and well-nourished patient grows shrunken and emaciated, and the face of youth is transformed into the shrivelled visage of old age. As the disease advances cerebral dis- order becomes more and more marked. The eyes are staring, bloodshot and always open, frequently with dilated pupil; the speech is abrupt, rapid, and incoherent, and at length there is confirmed delirium. Some- times remissions occur, and the patient eats, and even drinks, with great difficulty, how- ever. Towards the end such a remission, with complete subsidence of agony and agi- tation, is not uncommon. But this relaxa- tion is only a delusive calm, the prelude to dissolution, which is usually unattended with violent symptoms. Death ordinarily ensues from asphyxia. The duration of the dis- ease is generally from two to five days. It has been known to terminate within twenty- four hours, four of such cases being recorded by Thamhayn, while in a case mentioned by Tardieu life was prolonged for nine days. It is now quite generally admitted that although hydrophobia may be originally due to a blood-contamination, its action when developed is manifested exclusively through the nervous system, and principally that portion whose functions are governed by the medulla oblongata. In man the most careful examinations of those who have perished from hydrophobia have proved inconclusive as to the pathogeny THE FAMILY PHYSICIAN. 51 of the disease. In some instances the cere- brum, cerebellum, medulla oblongata, spinal cord, and eighth pair of nerves, in both origin and distribution, have been found apparently normal after the closest scrutiny with the naked eye as well as skilful micro- scopical investigation. Congestion, effusion of lymph, and even softening, have occa- sionally been observed in portions of the brain, medulla, or cord, but these and all other lesions thus far discovered in the body can only be regarded as results of the dread- ful disturbance in the nervous centres and respiratory and circulatory systems. Auten- reith, Brandreth, and Sallin have seen the nerves communicating with the cicatrix in- flamed. The distinctive character, however, of these disease-germs remains to be estab- lished. There is a special hysterical or mental hydrophobia, as Trousseau named it, induced by emotion on seeing hydrophobic patients, through fear of the disease after having been bitten, or even in very nervous people from simply hearing the description of a case. In this spurious hydrophobia there is only difficulty in swallowing, and no convulsions, scantiness of urine, or ele- vation of temperature. It is very rarely fatal. When once the rabific virus has declared its presence in the human system, all meas- ures hitherto adopted would appear unavail- ing to arrest its course. With our present knowledge the most satisfactory treatment after the disease has appeared consists in simply fulfilling rational indications—viz. by palliating the symptoms as far as possi- ble, excluding all controllable causes of mental and physical disturbance, and sup- porting the powers of the system with stim- ulants and appropriate alimentation. There is no doubt, however, that we have at our command effectual prophylactic means for destroying the poison, provided they be em- ployed within a reasonable time after the infliction of the injury. These precautions consist in the application of a ligature, if possible, to impede the circulation from the wound, in sucking the wound, and in its thorough cauterization, nitrate of silver be- ing the most valuable agent; but if this be not available, the hot iron, a burning coal, potassa fusa, or almost any acid may be used. Hypertrophy [Gr. vwep, "over," and rpov, "nourishment"], in pathology, the over- growth of any part or organ, or the dis- proportionately large size of such an organ. Hypertrophy is simple, homoeoplastic, het- eroplastic, or hyperplastic, these terms de- fining the character of the added material which gives the increased size. It may be caused—1st, by an increased exercise of the part, an exemplification of which we have in the blacksmith's arm; 2dly, by an in- creased supply of blood to a part, the part being healthy; 3dly, from some local de- rangement, as may be seen in exostoses, fatty tumors, etc. The treatment of hyper- trophy has been very unsatisfactory; in fact, we can do next to nothing for patients suffering from the first and second varieties. The third should be removed by the knife if any inconvenience is caused. Hypochondria (pi.), [Gr. rd vnoxdvdpia, the regions "under the cartilages"], in anatomy, the regions of the abdomen on either side of the epigastrium. The name is also given to the diseased condition of late more frequently called hypochondriasis by the medical profession. Hypochondriasis [so-called from the old belief that the hypochondria were the seats of the disease], a morbid state of mind, more common in men than in women, in which the patient imagines that he suffers from diseases which he does not possess, and in which he suffers from subjective sensations entirely unaccounted for by the objective signs of disease in his case. The disease itself is real. It may result from dyspepsia, from sexual excess, or from other causes in- terfering with the nutrition of the nerve- centres. The disease may amount to posi- tive insanity, and is then classed as melan- cholia. Medicine and hygienic regimen of- ten do but little good. Cheerful compan- ionship, fishing, hunting, and boating, long journeys, even the reading of well-selected novels—in fact, anything which will divert the mind from its habit of morbid self-ob- servation—will be found useful. Hyste/ria [from vartpa, the "womb"], a peculiar nervous affection which in former times was supposed to have had its seat in the womb, but at the present day Hasse's theory of its origin is generally received— viz. that it arises from a nutritive derange- ment of the general nervous system, both central and peripheral. This may be caused by any organ of the body being diseased, and there can be no doubt but that it is de- pendent most frequently upon disorders of the uterus and ovaries, simply because these affections produce a deeper impression upon the nervous system. This condition of the nervous system may also be produced by improper nourishment. There is a predis- position to the disease manifested. A tend- ency, either congenital or acquired, plays a much more important part in inducing this affection than all the causes enumerated. Hysteria generally attacks women from the age of puberty to the decline of men- struation. It is of rare occurrence among men, and in them is produced in "a manner 52 THE FAMILY PHYSICIAN. similar to that in which it is produced in the opposite sex. Hysteria may manifest itself in a great variety of ways; in fact, it simulates almost every known disease, and often with the greatest care the prac- titioner is unable to differentiate them. The most common form, however, is the hyster- ical fit. In some cases this consists merely of the twitching of the muscles of a par- ticular region, as of the face, arm, or leg. In other cases the whole body is affected at once. The patient generally laughs and cries alternately; this is due to spasm of the group of muscles which operate in producing these acts. Another very common accom- paniment of these paroxysms is the so-call- ed globus hystericus; this consists in the sen- sation as of a ball rising from the uterus and ascending through the abdominal and thoracic cavities to the throat, and is caused by a spasmodic contraction of the oesopha- gus. The patient may scream, tear her hair and clothes, and beat her breasts. In severe cases we sometimes have loss of conscious- ness and convulsions; when this occurs it is almost impossible to distinguish it from epi- lepsy. The fits usually terminate with the discharge of a large quantity of almost col- orless urine. Perhaps the next most com- mon manifestation of the disease is hyper- aesthesia, either general or localized, but most frequently the latter. Under this heading would come hysterical peritonitis, in which the patient will complain of great pain and tenderness over the region of the abdomen; she will jump and cry out upon the slightest touch. Accompanying this condition there will be a rapid pulse and increased temperature. The characteristic of the hysterical affection is that the pain is not aggravated upon deep pressure, and if you distract the patient's attention from her trouble you can very often knead the abdo- men without the least discomfort to her. The " stitch in the side " of young girls and women can generally be ascribed to hys- terical hyperaesthesia. The opposite con- dition, anaesthesia, may occur sometimes, to such an extent that the patient will allow your finger to be thrust into her eye or needles to be plunged deeply into the flesh without wincing. Hysterical hemiplegia and para- plegia very often occur. They are very per- plexing cases, and can hardly be differenti- ated by any but a careful and experienced ob- server. Paralysis of the muscular fibres of the bladder, or spasm of its sphincter, is sometimes simulated. Hysterical patients very often pretend that they are suffering intolerably from retention of urine, and can only be relieved by the introduction of the catheter several times a day; which, indeed, seems to be all that they desire. When such an affection is made out beyond a doubt to be feigned, it is best to leave the patient to her own resources. Even in cases where this has been done, the patients have been known to drink their own urine in order to carry out the deception. Gravel and stone in the bladder are other diseases simulated; the patient will put common gravel in the urine after it has been voided and pretend to have passed it, or she may even place sand in the urethra. Watson records a case in which a young woman made the surgeons in one of the London hospitals believe that she had stone in the bladder, and who act- ually submitted to be tied upon a table in the position usually adopted for operations for lithotomy, before a theatre full of stu- dents, before the deception was discovered. Hysteria very commonly mimics affections of the spine and joints. Patients have been known to have been kept on their backs for months, and even years, and to have had blisters, leeches, and issues almost constant- ly applied for supposed disease of the spine, which subsequently was ascertained to be purely nervous. So with hip-joint disease, etc. There are many hysterical affections re- ferred to the fauces—aphonia or loss of voice, mock laryngitis or pharyngitis, stricture of the oesophagus, and many curious sensations. One patient imagined that a number of tape- worms came up from her stomach to her throat, filled her ears, and came out upon her tongue. Every time she attempted to catch them with her finger they would dis- appear. This occurred several times a day, and it was impossible to persuade her that such a thing could not happen. Among the other more common affections simulated by hysteria are pleurisy, consumption, cough, hiccough, indigestion, in which the patient swallows a quantity of air, and then pre- tends to be suffering from tympanitis and eructations; vomiting also sometimes ac- companies this hysterical dyspepsia, simu- lating cancer of the stomach. Very often patients suffering from hysteria have a de- praved appetite; they eat very little of any- thing, especially at table, and will hardly touch meat at all, except it be a little ham; they will devour slate-pencils, wafers, chalk, pickles, lemons, and such out-of-the-way articles. Notwithstanding this mode of life, their health does not materially deteriorate. We next come to speak of the treatment. This may be divided into two modes—viz. that of the paroxysm, and that between the paroxysms. In the first stage the dress should be loosened and plenty of fresh air admitted into the room. Spectators should not remain in the room, and the attendants should maintain quiet and composure. Cold THE FAMILY PHYSICIAN. 53 water may be dashed in the face; some- times it is necessary to continue doing this for quite a while (fifteen or twenty minutes), but the patients will generally succumb at last. Strong aqua-ammonia may be held to the nostrils. The bowels may be unloaded with an enema of soap and water, or, better, of mixtura assafoetida. Forcibly holding the patient's mouth and nose for a moment, thus suspending respiration, will often divert all the patient's energy to restore breathing, and at once break the attack. When great nervous excitement exists, chloral, bromides, opiates, valerian, musk, etc. may be given at short intervals. In the intervals between the paroxysms, or in the other forms of hys- teria, laxatives, tonics, and the correction of any diseased function should be our first care. Iron, in the form of the carbonate, Blancard's and Bland's pills, and the muri- ated tincture of iron, benefit most cases. Besides this, the patient may take assafoetida pills, infusion of quassia, cinchona bark, and quinia. Ichthyosis [Gr. Irfv:, a "fish ;" i. e. "fish- skin disease "J, a disease of the human sub- ject characterized by the presence of scaly growths in or upon the integument. Three distinct diseases have been called by this name: (1) Intra-uterine ichthyosis, in which the vernix caseosa, or glutinous secretion of the skin of the foetus, becomes hardened into a horny armor, crippling the development of the child and leading to its death. (2) True ichthyosis is a hypertrophy of the papillary layer of the skin and of the epider- mis. The patient is covered, as to a great part of the body and limbs, with unsightly scales of forms varying in different patients. This disease is thus far quite incurable. It is generally hereditary, but is not always so. Ichthyosis has been known to cover the skin of the knee after recovery from severe de- structive disease of the joint. Frequent bathing and anointing are useful, but never curative. (3) The so-called sebaceous ich- thyosis depends on excessive functional ac- tivity of the sebaceous glands, the secretion of which rapidly hardens into scales. This disease is often caused by some reflex dis- turbance, and is curable as a rule. IFeus [Gr. siledg, a " twisting;" Lat. vol- vulus or miserere mei], a very painful disease of the intestine, produced by mechanical obstruction, as by twisting, intussusception, or knotting of the entrail. Intense pain, per- sistent vomiting (sometimes stercoraceous), hiccough, etc. are characteristic symptoms. Intussusception, or the passage of a part of the intestine into the cavity of another part, is one of the most common conditions, as when the lower part of the small intestine is slipped down into the large intestine. The disease is very often fatal. Spontaneous re- duction of the displacement may occur; the intussuscepted part may slough away and an inflammatory process occur, resulting in re- covery ; dilatation of the bowels by the bel- lows may effect a cure. As a last resort, gas- trotomy may be tried with possible success. ImpetFgo [Lat. an " attack," from impeto, to " rush upon"], a skin disease, resembling eczema in being more or less diffuse inflam- mation, but resulting, unlike eczema, in pus- formation. The crusta lactea of young infants is one of its forms, which are rather numer- ous. True impetigo is not contagious. It frequently is cured by time alone, but if per- sistent should be treated with oxide-of-zinc ointment or some other mild stimulant. The so-called impetigo figurata is a distinct dis- ease, depending on the presence of Tricho- phyton tonsurans, a parasitic vegetation. Epi- lation of the part with irritant washes, as of corrosive sublimate, will cure the disease, which is truly contagious. Indigestion, or Dyspepsia [Gr. 6vg, "bad," and TriirTO), to "digest"]. Indigestion has many forms, and includes groups of symp- toms indicative of departure from one or many of the conditions of healthy digestion. The digestive process is complex, and is performed by the agency of the saliva, the gastric juice, and the intestinal, pancreatic, and biliary secretions. For the proper secre- tion of these several digestive fluids the blood must be in a healthy state, and be freely supplied to the glandular structure of the stomach and intestines. The innerva- tion essential to the digestive process de- mands moderation of mental activity, emo- tional tranquillity, vigor and healthful action of the nervous centres, especially of the sympathetic system. Tonicity of the mus- cular walls of the stomach and intestine is essential for the thorough contact and ad- mixture of food with the digestive fluids, for its transit through the intestinal tract, and for the regular evacuation from the bowels of undigested and excretory matter. Indigestion may be gastric or intestinal— often the two combined. It is either pri- mary—an essential disorder of the digestive apparatus—or secondary and symptomatic of disease in other organs. Obstruction of the circulation of the blood by chronic dis- ease of a large vascular organ—as the liver, spleen, or kidney—induces passive conges- tion of the mucous surfaces. Heart disease, rapidity of circulation, and elevation of temperature in fevers and febrile disorders cause gastro-intestinal engorgement, catarrh, and indigestion. When bile is imperfectly eliminated, when urea is imperfectly excre- ted by the kidneys, when fecal matter is retained and absorbed, the effete elements 54 THE FAMILY PHYSICIAN. circulating in the blood excite gastric or in- testinal or gastro-intestinal catarrh. Pri- mary or idiopathic indigestion includes all cases in which careful investigation has fail- ed to discover a dependency on other disease. It may be a simple functional disorder of digestion, or due to an organic cause in some part of the digestive tract. Functional dys- pepsia is termed atonic. Organic dyspepsia, if mild and due to temporary and slight lesions of the secretory surface, is termed irritative; if severe, it is designated chronic gastritis, a condition which by associated symptoms and physical exploration may be found to depend upon ulcer, cancer, or in- flammatory thickening. Atonic dyspepsia may be due to defective innervation—from continuous and exhaustive mental action; from emotional disturbances, as excitement, sorrow, fear; from prolonged exercise and fatigue; from dissipation. It may be caused by deficient supply and quality of the blood, inactive circulation from indolence and ne- glect of exercise, anaemia and impoverished blood from privation or recent sickness. De- ficient or perverted secretion of digestive fluids results. Reversely, digestion may be interfered with by excess of blood and gas- tric catarrh, when neglected cleanliness or chilling of the skin or cold extremities de- termines blood to internal parts. Obesity, indolence, general debility may lower the tonicity of the muscular structure of the stomach and intestines, and weaken the peri- staltic movements, causing failure in the contact of food with digestive fluids, and resulting in its accumulation and fermenta- tion. As a rule, however, nerve-force, blood- supply, and digestive apparatus are not pri- marily at fault, and are adequate to ordinary digestion, the majority of indigestions being the result of gross excesses of diet and vio- lations of hygienic law, excess of food, too frequent meals, rapid eating with incomplete mastication and insalivation, food unfit for digestion or improperly and insufficiently cooked, the habitual use of condiments, rendering the peptic glands dependent upon their stimulus, the imbibition in excess of liquids, as water, tea, or coffee, at meals, causing dilution of the gastric juice. Alco- holic stimulants create temporary and arti- ficial appetite, but soon destroy healthy di- gestion. Tea, coffee, and tobacco impair the innervation of the stomach. The chief symptoms of gastric indigestion are sense of fulness, weight, distress, and dull pain over the stomach, coated or irrita- ble tongue, foul breath, perverted appetite —usually poor in the morning, and often morbid and irregular—sometimes nausea and vomiting, eructations of gas, regurgita- tion of acid or alkaline liquids and of food, often constipation, and less often colicky pain, with irregularity and looseness. There may exist lassitude, mental inactivity, drow- siness, cranial oppression, headache, vertigo, sometimes clouded vision, diplopia or double vision, and numerous nervous symptoms and perversions of the senses may exist; short- ness of breath, sighing respiration, pnecor- dial distress, palpitation and irregular action of the heart. There may be poor circula- tion; relaxed and pallid or sallow surface and complexion; cold hands and feet; in women, menstrual disorders. With the more marked and aggravated symptoms there may be mental depression, anxiety, despondency, and apprehension, constituting hypochon- dria. A diagnosis of the form of dyspepsia is essential to a correct treatment. Atonic may be distinguished from irritative dyspep- sia by the following differences: In Irritative Dyspepsia. In Functional or Atonic Dyspepsia. 1. Deficiency or irregu- larity of appetite, absence of thirst. 2. Ingestion of food af- fords sense of com- fort for a time. 3. Food retained. 4. Condiments and stimulants craved, aid digestion, and cause sense of com- fort. 5. Languor and inapti- tude for exertion during digestion. 6. Tongue pale, broad, flabby, thinly fur- red. 7. Breath foul. 8. No fever. 9. Persons in general good health and flesh. 10. Constitutional symp- toms few. 1. Morbid craving for food, morbid thirst. 2. Ingestion of food causes distress. 3. Food often ejected when taken, or soon after. 4. Condiments and stimulants create or intensify distress. 5. Pain and mental dis- tress during diges- tion. 6. Tongue small, com- pact, red, with ele- vated papillae or sensitive abraded patches. 7. Breath may or may not be foul. 8. Often slight fever. 9. Reduced health, bad nutrition, and ema- ciation. 10. Variable general ef- fects. The symptoms of functional and irritative dyspepsia often coexist. In functional dys- pepsia the fermentation of food develops gases. Eructations may be of carbonic acid gas from acetous fermentation, of hydrogen and carbonic acid gas from decomposition of hydrocarbons or fatty food, or of sul- phuretted hydrogen from decomposition of nitrogenous substances, as meats, eggs. Of regurgitated liquids, the most common is a clear, opalescent, insipid, alkaline liquid, sometimes saltish or brackish, probably the accumulation in the oesophagus of saliva, and its frequent rising in the throat is known as waterbrash or pyrosis. In gastric catarrh gelatinous mucus may rise in the throat. The regurgitation of acid, acrid liquid causes sense of burning in the stomach, THE FAMILY PHYSICIAN. 55 beneath the sternum, and in the throat— technically, cardialgia, popularly termed heartburn. Such fluid is usually serum or sero-mucus, containing acetic or lactic acid. If brown, acrid, bitter, rancid, and offensive, it is due to the conversion of fatty food into butyric acid. Food may be regurgitated at various stages of its digestion. When food is ejected many hours after ingestion, it may present products of fermentation— sporules of Torula cerevisia;, or sporules ag- gregated into segmentated, cubical masses, known as Sarcinas ventriculi (sarcina, a "wool-pack"). Coffee-ground substance in ejecta is due to blood which has undergone gastric digestion, and indicates an abraded, ulcerated, bleeding surface. The accumu- lation of food and its ejection en masse hours after ingestion denote obstruction at the lower or pyloric orifice. The prevalent idea that gastric juice is often regurgitated is erroneous. Bile appears in regurgitated fluids seldom, and in vomited matter only after prolonged or violent emesis. In aged persons a steady progressive loss of appetite, progressive inanition and emaciation, and death from slow asthenia, without other symptoms of indigestion or evidence of disease in other organs, result from degen- eration of the gastric and intestinal tubules, the peptic glands. When fatty food passes in the faeces undigested, disease of the pan- creas may be suspected. Atonic dyspepsia predisposes to acute in- digestion, sub-acute gastritis, gastro-enteric catarrh—the cholera morbus of adults and cholera infantum of children — whenever exciting causes are superadded, as the im- bibition of cold water or eating acrid fruits, chilling of the heated body in summer. Indigestion may at first induce looseness of the bowels, irregular action, or diarrhoea, but ultimately produces constipation. In- digestion, by developing lactic acid in ex- cess, is the frequent cause of rheumatism. It is the source of the lithic-acid or gouty diathesis. Indigestion is the frequent cause of urinary precipitates. Imperfect digestion of nitrogenous food gives rise to oxalic acid, oxalate of lime in the urine, irritation and congestion of the kidneys and bladder. Indigestion in young and susceptible chil- dren and infants is the most frequent cause of convulsions and sudden febrile attacks. It may be the chief or only cause of chorea (St. Vitus's dance). Chronic irritative dys- pepsia is most often the result of alcoholic excess, less often of excessive errors of diet, or may be symptomatic of gastric ulcer, pyloric constriction, or malignant disease. In the treatment of indigestion regula- tion of diet alone often effects a cure. The diet should be nutritious, moderate in quan- tity, taken at regular intervals, and slowly eaten. The food at breakfast should be simple and laxative, at dinner substantial, at sup- per light. Of dishes there should be variety, yet simplicity, including animal food, vege- tables, and fruits in restricted quantities. Bread should be stale or aerated. Milk may be freely taken, corrected with soda or lime- water. Fatty food, grease, sugar, and pastry should be avoided. Artificial adjuvants to the diet, as Liebig's prepared food, Ridge's food, and malt extract, are of value. Drink of any kind at meals should be very limited. Attention to general regimen is essential. There must be outdoor exercise, freedom from mental stress, from physical fatigue, and dissipation in any form. By clothing, active friction, and judicious bathing the external circulation is kept vigorous. Tendency of the food to decom- pose demands correctives. For the acid stomach, bicarbonate of soda, the bicarbon- ate of potash, or lime-water; for alkaline fluid and gastric mucus, dilute mineral acids and acidulated drinks. Bismuth, either the subnitrate or subcarbonate, is the remedy for pyrosis. When the stomach fails to digest albuminoids, pepsine may be given. Pancreatine will aid the intestinal digestion of fat. Fermentation of food, with fetid products and foul breath, may be treated by the sulphite, bisulphite, or hyposulphite of soda, the sulpho - carbolate of soda; charcoal is also efficacious. In atony of the stomach, carminatives, as ginger, cal- amus, capsicum, and compound tincture of cardamum, stimulate glandular secretion; bitter vegetable tonics, chamomile, quassia, calumbo, gentian, wild-cherry bark, casca- rilla and cinchona barks, create appetite, and nux vomica increases the muscular tone and activity of the stomach and intestines and prevents flatulence. Quinine and fer- ruginous tonics, as the citrate of iron and quinine, the lacto-phosphate and carbonate of iron, and Blaud's pills produce general vigor, improve the blood, and aid digestion. Laxatives are essential when constipation exists; violent cathartics are to be avoided. Laxative food, as the coarse cereals and ripe fruit before breakfast, may be tried. Tamarinds and figs, St. Germain tea, senna, and magnesia may be used to stimulate the bowels to action. Often active exercise, walking, or horseback riding will suffice. Rubbing and kneading the bowels or the application of electricity to the abdominal muscles will cure obstinate constipation. Rhubarb, podophyllin, or dried ox-bile in small quantities may be needed to increase the secretion of bile, aloes to unload the rectum, belladonna and nux vomica to create permanent tonicity and regular action 56 THE FAMILY PHYSICIAN. of the bowels. A judicious combination of these remedies in a tonic-laxative pill may be taken until the stomach and intes- tines resume healthy and vigorous activity. Saline purges are to be avoided. But the milder mineral waters may be taken when acid indigestion is present or there is a per- sonal tendency to rheumatism or gout. InebrFety [Lat. inebriare, "to make drunk"], in the present acceptation of the term, is used to denote the diseased condition of the system produced by the habitual use of alcohol. Its synonyms are alcoholism, dipsomania, and oinomania. Al- cohol introduced into the circulation acts upon, and to a certain extent destroys, the red corpuscles of the blood, and thus, sec- ondarily, affects all the organs of the body. Its most common mode of introduction into the system is in the form of spirituous and fermented drinks; and in those addicted to its habitual use the principal lesions are chronic hyperaemia and subsequent soften- ing of the brain, cirrhosis and fatty degen- eration of the liver, fatty degeneration of the kidneys, and fatty degeneration of the heart. Formerly, inebriety was regarded as a crime, but within a few years science has shown it to be a disease, and institutions have been established for its treatment and cure. Statistics from these institutions have demonstrated—I. Inebriety is a disease, and is curable. II. Relapses may or may not occur. The patients in hospitals for the treatment of inebriates may be divided into three classes—viz. I. Those who by social indulgence, without hereditary taint, have become inebriates. These, as a class, are curable by the aid of an institution. II. Those in whom the disease is inherited, in which cases it manifests itself in paroxysms ("sprees") at variable intervals. These are more difficult to restore to health. III. Those who seem totally depraved in all their in- stincts, and exhibit no desire for restoration to health. These, as a class, are incurable, and should, for the protection of society, be placed under permanent restraint in insti- tutions distinct from those of a reformatory character. Carefully prepared reports from hospitals for inebriates show that a very large percentage (between 50 and 60) of the patients treated in them are restored permanently. (See Delirium Tremens, Dipsomania, Intoxication, Methoma- NIA.) Infantile ParaFysis, paralysis of a mus- cle, group of muscles, a limb or side, com- ing on suddenly in an infant or young child. It is due to congestion of the brain or spinal cord, often excited by the irritation of teeth- ing, indigestion, or constipation. Most cases are temporary, others leave squint, club-foot, paralysis, and shortening of a limb. The affected member must be exercised by knead- ing and electricity, to prevent its wasting while time permits the lesion of the nervous centre to be removed. Cod-liver oil, iron, tonics, and out-of-door life are the requi- sites. (See articles Club-Foot and Squint- ing.) Inflammation [Lat. inflammo, inflamma- tum, to " kindle," filamma, " flame"], a mor- bid process characterized by heat, redness, pain, and swelling. The predisposing cause may be anything which tends to influence injuriously the animal economy—plethora or anaemia. When a part has once been the seat of inflammation, it is very liable to be affected again under the slightest exciting cause. Age is a predisposing cause of in- flammation ; in infancy the parts most sub- ject to become inflamed are the bowels, pharynx, larynx, and brain, whereas dur- ing adult life these parts are seldom affect- ed, the favorite seat then being the lungs, heart, urinary apparatus, etc. Sex exerts a certain influence; a female is more apt to suffer from peritonitis, phlebitis, or cellu- litis in consequence of the parturient act. So the temperament, food, occupation, cli- mate, etc. all influence, to a greater or less extent, the susceptibility of the individual to be attacked by inflammation. The excit- ing causes may be divided into the consti- tutional and local; the former includes all those agents which are capable of rendering the blood impure, as poisonous gases, cold, heat, etc. The local cause is generally an injury of some kind, either chemical or me- chanical. Every vascular part may be the seat of inflammation, and usually in pro- portion to the amount of its vascularity. It also seems necessary that nerves should be present. Cartilage contains no nerves and but few vessels, and is therefore rarely the seat of inflammation. Epidermis, hair, and the nails are never inflamed, being destitute of blood-vessels, nerves, and lymphatics. Inflammation is generally divided into the acute and chronic varieties; the former runs a rapid course and is attended by well- marked symptoms—pain, heat, redness, and swelling. These have been given as the symptoms of inflammation from the time of Hippocrates. The swelling is caused by enlargement of the vessels, and more par- ticularly from serous effusion, which takes place into the adjacent tissues; at a later period we have plastic exudation, which in the end tends to lessen the size of a part. The redness is a leading feature, and is due to enlargement of the vessels and an in- crease of the coloring-matter of the blood. Pain is not essential to"the disease—pneu- monia and encephalitis are not painful dis- THE FAMILY PHYSICIAN. 57 eases—but external inflammations are al- ways attended with pain, which is due to pressure upon the ultimate.sensitive nervous filaments. Serous membranes stand next to fibrous structures of joints in the severity of inflammation, although we may have serous membranes inflamed without pain, as in puerperal peritonitis. The heat is a direct result of hyperaemia. It is chiefly felt in external inflammations; the part receives more blood, and. is consequently of a higher temperature, than the rest of the surface, but it never rises above the heat of the blood. Acute inflammation is always attended by more or less fever, which may be ushered in by a chill. The pulse runs up to 100-120, the respirations are increased in number to 25 or 30 per minute, and the temperature is raised to'102°-104° F.; the secretions are suppressed, and there is headache and some- times delirium. Many attempts have been made to ascertain the exact changes which take place in a part attacked by inflamma- tion by artificially producing an inflam- mation in the web of a frog's foot or the wing of a bat, and closely watching the changes under a powerful microscope; these observations have led to the following con- clusions : In inflammation the first change is in the ganglionic system of nerves, but of this system we know nothing except its effects. This nervous system influences the various determinations of blood, as seen in blushing and the local temporary engorge- ment of nervous women; as also conges- tions, which are not mechanical in their cause, but occur from a passive state of the vessels. Next we will notice the changes which are seen to occur in the blood-vessels. There is at first active congestion of the part, and this condition is caused by inter- nal or external irritation. Soon stagnation is observed to take place at points. In the natural state the red blood-corpuscles never touch the walls of the capillaries, but in inflammation this rule no longer obtains, and they begin to adhere to the walls and to each other. This is known as the stasis; as it increases the vessels continue to dilate, and very soon after the stasis is established the vessels begin to exude their contents, which make their appearance amongst the tissues. This exudation is not a coagula- tion of the blood as seen outside the body; it is serous at first, but is soon followed by an effusion of lymph or liquor sanguinis, which, according to the old theory, might be organized into false membrane or de- generate into pus, it depending on the tis- sues involved and the constitution of the patient. At the present time, however, Cohnheim's theory of the formation of pus is the one generally received—viz. that the corpuscles are identical with the white blood-corpuscles, which are exuded through the walls of the vessels. In process of time the false membrane becomes smooth. It has not yet been ascertained whether nerves are formed in the tissues or not. Two theo- ries are given to account for the formation of vessels in these new productions—viz. Vogel's and Hunter's. Vogel believes that he has seen the membrane itself produce the blood, and afterwards the vessels to con- tain this blood, and he says that finally these new vessels communicate with the old ones. Hunter believes that the new vessels are given off from the old ones. After ves- sels have been formed in these new tissues contraction commences, and both the mem- brane and the vessels become smaller and firmer. This contraction sometimes proves a serious matter, as in the contraction of bands around the intestines, especially in the neighborhood of the rectum; the effects of the contraction are also serious about the pericardium, causing at times hypertro- phy of the heart; the pleura suffers least from it. The duration and character of the in- flammation vary with the condition of the part affected and the constitution of the patient. When once fairly established, it may destroy life by exhaustion or by inter- fering with the function of some important organ, as the lungs or heart. It may also terminate in resolution, suppuration, or mortification. Resolution consists in the restoration of the affected part to its normal condition without suppuration having taken place. It is by far the most favorable ter- mination of inflammatory action. Sup- puration consists of the formation of a fluid called pus, as described above; it is a yel- lowish liquid, in which float numerous small round granular corpuscles. When the pus is thin, dirty, and acrid, it is called ichor. When suppuration continues for any length of time, it gives rise to a fever known as hectic fever. This is diurnal in character, commencing with a chill, followed by a fever, and then sweating. The chill lasts from half an hour to an hour, the fever from one to two hours. In a great many cases the three stages are not well marked, one, or even two, of them being oftentimes omitted. The inflammatory action may be so intense as to deprive the part of its proper supply of blood, and so cause ulcer- ation and mortification (see Gangrene); this condition is attended by a symptomatic typhoid fever, the symptoms of which are— dry tongue with sordes, trembling, restless- ness, delirium, muscae volitantes, pulse fee- ble, small, and frequent, involuntary evacua- tions. 58 THE FAMILY PHYSICLvN. Treatment of Inflammation.—We have local and constitutional means for combating this condition; sometimes one alone will do the work, but generally we employ them con- jointly. The first thing to be done is to re- move the cause, if discoverable; if not, the bowels should be freely moved once a day, and the skin and kidneys be made to act by the administration of diaphoretics and diu- retics. Careful attention should be paid to the diet and regimen of the patient, and heat and moisture applied to the inflamed part, either in the form of poultices or spon- gio-pyeline or the hot-water bath. If the patient be plethoric and the pulse hard and full, it will be a great benefit at times to bleed him. This practice has been much decried of late, but surgeons are not very averse to local blood-letting, which may be done by scarifications with a lancet, by wet or dry cupping, or leeches. It seems to afford instant relief to the patient by removing pressure and consequent irritation of the in- flamed part. Cold evaporating lotions con- tinuously applied are a great relief. They cause the capillaries to contract, and there- by diminish the afflux of blood. Inflammation of the Bow/els. See Peri- tonitis. Inflammation of the Brain. See Brain Fever and Meningitis. Inflammation of the KicFneys. See Bright's Disease and Renal Diseases. Inflammation of the Liv/er. See Hepa- titis. Inflammation of the Lungs. See Pneu- monia. Inflammatory RheiFmatism. See Rheu- matism. Influen/za [It.; as if produced by the in- fluence of the stars], an essential, infectious, epidemic febrile disease, characterized by a variable degree of constitutional disturbance, especially nervous depression, and having a local expression in irritation and catarrhal inflammation of the air-passages and their appendages. The name influenza" is Ital- ian, indicating " the influence " of a prevail- ing atmospheric cause. In France it is termed la grippe, from agripper, to " seize," indicating the sudden, precipitate onset of the epidemic and of the individual attack. It is also termed epidemic catarrh, epidemic bronchitis, and, better, epidemic catarrhal fever. It is described as first prevailing in Europe in the tenth century, and later in the years 1311,1387, and 1403. But its cer- tain and undoubted record begins with the epidemic of 1510. Since that time to the year 1875 there have been ninety-two epi- demics, of variable severity and at irregular intervals. These epidemics are singularly uniform in identity of characteristics and in obedience to law of origin and diffusion. The disease appears suddenly in the E. or N. E., usually in the N. of Europe, excep- tionally in the Indies or Northern Asia, and travels to the W. It travels in cycles, in- vading the whole of Northern Europe, of- ten extending to America, and exceptionally felt in the equatorial regions and the south- ern hemisphere. Unlike cholera, its diffu- sion does not depend on human commerce. Its progress is rapid, a great wave from E. to W. precipitating itself upon communities and countries with a suddenness warranting the names popularly applied to it—" light- ning catarrh," "he petit courrier," "la grippe." Less often it appears coincidently at places far removed, as at the Cape of Good Hope and London in 1836. In its zone of progress it often appears simultaneously at many isolated foci, from which it seems to radiate until disseminated over vast areas. Its influence is not confined to the continents, but is immediately exerted at mid-sea upon all who sail into the districts of atmospheric infection. Appearing in a community, it attacks a majority of its members, of both sexes, of all ages and social position, and with a rapidity precluding the idea of com- municability. No nationality is exempt, and as a rule only a fractional part of the population escapes its effects. It would ap- pear to attack preferably women, next adult males, and lastly children. In some epi- demics children are exempt. During the prevalence of influenza the animal vitality is lowered, the type of other diseases is mod- ified, assuming adynamic or typhoid forms, and tending to a greater general mortality. Influenza is not confined to man, but often extends its epidemic influences to the do- mesticated animals, especially the horse, and is known as the epizootic. In England the epidemics of 1728, 1732, 1733, 1737, 1743, 1803, 1831, and 1837 were accompanied by the epizootic among cows, horses, and dogs. The pestilential epizootic extending through- out the U. S. in 1872-73, attacking in New York 16,000 horses, was an epidemic of in- fluenza, prevailing with great severity. The influenza is first recorded in America in 1577. The chief epidemics in Europe have extended to this country. The most notice- able ones are that at the close of the war of 1812, those of 1843, of 1872, and the recent season 1874-75, in which pneumonia has existed as a frequent and fatal complication. Of the intimate nature of the subtle atmo- spheric or telluric cause of influenza nothing is definitely known. Schonbein regarded an excess of ozone in the air as producing bronchial irritation. Prout attributed the disease to selenuretted hydrogen. Much has been written of its concurrence with the ap- THE FAMILY PHYSICIAN. 59 pearance of comets and meteoric showers, and the opinion is in favor that electrical and magnetic disturbances of the atmosphere are related to the epidemics. The advocates of the " germ-theory of disease " regard in- fluenza as due to the wide dissemination, by air-currents, of animalculae or cryptogamic vegetable products—malarial emanations. Ehrenberg describes "dust-fog currents" in the higher strata of the atmosphere, from which many genera of animalcules may be collected. The epidemic of influenza occurs at all seasons of the year, often in the spring, and in both warm and cold, in dry and damp or foggy weather. The usual duration, in one locality, of an epidemic is from four to six weeks, exceptionally much longer. There may be local recurrences in the same season, but as a rule the victims of the first are ex- empt from the second attack. As regards the disease, it is thought that a specific poison is absorbed and circulates in the blood, irritating the nerve-centres, producing prostration and febrile disturb- ance, and causing hypersecretion and in- flammation of the mucous lining of the air- passages. The symptoms vary in severity in different epidemics and in individual cases. The onset is sudden, announced in severe cases by a marked rigor, more often by chill and shivering, alternating with flashes of heat. Then follow general lassi- tude, debility, nervous prostration, soreness and stiffness of the limbs, pains in the neck, back, and loins, headache, frontal oppres- sion, pain in the orbits, cheek-bones, and root of the nose, injection and sensitiveness of the eyes, with copious flow of tears—often heated, the " fiery tears " of the early records —sneezing and tingling, followed by watery and often acrid discharge from the nose, soreness of the tonsils, Eustachian tubes and ears, experienced in swallowing, hoarseness, a short, frequent, harassing cough, with slight expectoration, and a slight fever of the remittent form, having its exacerbation towards evening. The fever is seldom pro- nounced, but the restlessness, irritability, ex- haustion, and mental depression are marked, and usually disproportionate to the bronchial complication. In other cases there is sore- ness, tightness, and pain beneath the ster- num, dyspnoea, sense of suffocation, and danger of capillary bronchitis or pneumonia. These unfortunate complications are the chief causes of death from influenza, and occur mainly in the aged, in invalids, and in delicate children. The usual duration of mild cases is from three to five days, of grave cases from seven to ten days. The termination of the disease is often as sudden as its onset, and frequently occurs with a critical and profuse perspiration or diarrhoea. The mortality from uncomplicated influenza in healthy persons is very slight. Influenza has no pathology indicative of its specific nature, and presents only the lesions of the associated catarrh—tumefaction and redness of the mucous lining of the nose, the tear- duct, and eyelids, the frontal and maxillary sinuses, of the throat, Eustachian tube, and membrana tympani, of the larynx and bron- chial tubes, and the lesions of pneumonia when it exists. The majority of cases are mild and require no treatment. A purge at the outset may shorten their duration. More marked Cases require a preliminary purga- tive, a low diet, the avoidance of exposure to cold, resort to hot draughts, as of lemon- ade or elder-bloom tea, to stimulating foot- baths, to the use of Dover's powder, Tully's powder, spiritus Mindereri, or other reme- dies to secure free perspiration, and the re- lief of bronchial congestion by inhalation of steam, by ammonia, or by stimulating expectorants. Headache and distress in the nose and orbits, due to irritation of the Schneiderian membrane and its processes, may be relieved by the inunction of oil or grease or by the insufflation of warm ano- dyne solutions. Quinine in doses of five grains three times a day, if taken at the be- ginning, may cut short the attack. When the bronchitis tends to become capillary, quinine or tincture of bark is indicated to support the strength, ammonia to favor the liquidity and discharge of mucus, and the oil-silk jacket to favor free secretion. The extensions of pneumonia may be limited by arterial sedatives, carbonate of ammonia, quinine, and anodyne poultices or fomenta- tions. It is essential to proper treatment to remember that blood-infection is primary and bronchitis or pneumonia is secondary; the constitutional disease will admit of no depressing remedies, and the speedy termi- nation of the inflammatory complications will follow supporting measures. During epidemics of influenza the aged and feeble should keep within-doors in well-warmed rooms, and partake of quinine, ammonia, and guarded but nourishing diet, as meas- ures of prevention. IntenFperance. See Delirium Tremens, Dipsomania, Inebriety, Intoxication, and Methomania. IntermiFtent Fe'ver, Ague, Fever and Ague, an essential, periodic fever resulting from infection of the blood by malaria or marsh-miasm. Malaria emanates from de- composing vegetable matter exposed to the action of the air and the sun's heat. It exists in swampy districts and in low, damp, undrained places, upon the banks of rivers, upon inlets of salt water, where variable water-level and tides expose a saturated 60 THE FAMILY PHYSICIAN. soil to the atmosphere. Malaria is most concentrated and intermittent fever most prevalent and severe in the tropics, where vegetation is luxurious, and a soil enriched by decaying plants and falling foliage is subjected to the extreme influences of alter- nate seasons of rain and drought. In tem- perate regions it is present in new districts, disappearing as the land is populated, cul- tivated, and drained. It may appear in cities by the exposure of marshy subsoil when excavating to build, or by the escape of malarial air from defective street-sewers constructed in a swampy substratum or emptying on a malarial water-course, whose tidal changes dam back marsh-miasm, to escape in the various quarters from which the sewers extend. Intermittent fever occurs in paroxysms separated by intermissions or non-febrile periods. The paroxysms may recur daily, constituting the " quotidian " form, or on alternate days, the " tertian " form, since it recurs on the third day, in- cluding the previous attack. There is also a " quartan " form. Exceptionally, there may be a " double quotidian," with one strong and one mild attack each day; a " double tertian," with a daily onset, that of every second day being relatively weak ; a " double quartan," having two attacks in every three days. Febrile paroxysms usu- ally recur at a definite hour each day or alternate day. A recurrence of successive paroxysms at an earlier hour for each attack is termed " anticipating," and indicates an increasing malarial influence. When the paroxysms come at a later period, with suc- cessive attacks, it is termed " postponing " or " retarding," and indicates a subsidence of the malarial influence. Paroxysms may occur a few hours after exposure to malaria or after a period of incubation as long as two weeks. A paroxysm has three distinct periods or stages: (1) cold stage; (2) hot stage; (3) sweating stage. The average duration of the cold stage is one-half to three-quarters of an hour; it may be a few moments or two to three hours. It begins with shivering, chilliness in the loins, ex- tending to back and limbs, muscular tremor, the lips quiver, teeth chatter, and the whole body is shaken. The respiration is sighing, the pulse feeble, the face pale or livid, the nails livid, the fingers waxen and cold. The general surface is pale, cold, often shrivelled. The thermometer in the mouth or armpit, how- ever, reveals an increased temperature of the blood even in the cold stage, the blood having been expelled from the skin and ex- tremities by the involuntary contraction of the elastic tissues of the skin. During the first stage there is therefore a determination of blood to internal organs, which may be dangerously congested, constituting the " pernicious " or " congestive " forms. Headache, vomiting, tenderness over the liver and spleen, are symptomatic of such congestion. The transition from the cold to the hot stage is gradual; chilliness ceases, flashes of heat are felt, "the coldness melts away." The skin becomes hot and red, pulse full and bounding, the face flushed, headache increases, the temper- ature of the surface may be 105° or 106° F. The duration of the hot stage is from three to eight hours. The third or sweating stage at first is gradual; moisture appears on the face, soon on the trunk and extremities. Heat, headache, thirst, and restlessness sub- side, the temperature falls rapidly, the per- son is drowsy, falls into long and refreshing sleep, with profuse or slight sweating. The duration of this stage is from three to four hours. During the intermissions or apy- rexial periods there may be good health, or in graver cases impaired digestion, debili- ty, pallor, or sallow, cachectic complexion. Malaria impoverishes the red corpuscles and lessens the albumen of the blood. In- termittent fever tends to recur when incom- pletely cured, either in marked paroxysms or in less pronounced " latent," " masked," " concealed" forms, vague symptoms of chilliness and weariness known as " dumb ague," or in periodic neuralgia. The spleen is often permanently enlarged, and is termed " ague cake." The periodical recurrence of the paroxysms is due to successive efforts at elimination, the interval being the time required for the zymotic material of malaria to redevelop and impress the system. The paroxysms require no treatment other than warm drinks and blanketing during the cold stage, cooling drinks and sponging during the febrile or hot stage. The treat- ment for the prevention of the paroxysms is to be in the periods of intermission. The chief of remedies is the Peruvian or cincho- na bark, and the alkaloids derived from it. Quinine is mostly used in the form of the sulphate and bisulphate, less often the mu- riate. Cinchonine is an alkaloid resembling quinine, but less powerful. The mother- liquor from which these alkaloids are pre- cipitated is evaporated, and an impure, crude sediment, in part quinine and' cinchonine, and mainly quinidia and cinchonidia, or amorphous alkaloids, is obtained, and is much used—known as " chinoidine." Sali- cine, the alkaloid of willow bark, berber- ine, piperine, apiol, eucalyptus, and other vegetable substitutes are weaker and less efficacious than quinine. Crude or unbleach- ed quinine, an inexpensive article, has re- cently been ascertained to have the full effi- cacy. Quinine is given either in one full THE FAMILY PHYSICIAN. 61 dose of ten or more grains or in divided doses of five grains three times a day to break the paroxysms, and continued in smaller doses for many days to prevent their recurrence. Fowler's solution of arsenite of potash is second only to quinine in power. Nitric acid, sulphites of soda, ferrocyanide of iron, chloride of ammonium are also used. The patient may be more efficiently and permanently cured by combining chola- gogue cathartics, and subsequently employ- ing iron and tonics generally. The preven- tion of intermittent fever is to be sought by soil-drainage, by avoiding damp night air, and sleeping in closed rooms well above the ground. The sunflower freely planted ad- jacent to dwellings has been considered pro- tective by absorbing malaria, and more re- cently the Eucalyptus globulus, or Australian fever tree, has been extensively planted in Algiers, at the Cape of Good Hope, and in Cuba, and is asserted to lessen, or even eradi- cate, malaria by its presence. Intoxication [Lat. in, and toxicum, "poi- son "], the cumulative effect of an acro-nar- cotic poison on the nervous centres. The term is most commonly used to designate the condition of a person who has been brought under the influence of alcohol by successive imbibitions during a short space of time, but should not be confined exclu- sively to the poisoning by alcohol; opium, stramonium, cannabis indica, and all the poisons belonging to the above-mentioned class, will produce intoxication when taken in sufficient quantity. Intoxication may be divided into the acute, sub-acute, and chronic varieties. Acute intoxication is a disease very rarely seen, even by the physician. It is produced by drinking a large quantity of some spir- ituous liquor in a very short space of time. This is followed soon afterwards by sudden coma (loss of sense, sensation, and voluntary motion), which may be complete or incom- plete. We have present here the symptoms of coma—viz. stertorous respiration, dila- tation of pupils, frothing at the mouth, etc. Unless assistance speedily arrives these symptoms generally terminate in death in from half an hour to five or six hours. Every endeavor should be made to arouse the patient from his lethargic condition. An active emetic, as sulphate of zinc, may be administered, or, better still, the stomach- pump should be used to evacuate the stom- ach. Ammonia may be given as an anti- dote, and if the patient be able to swallow he should take large draughts of tea. The sub-acute form may be seen any and every day in the week. It is the ordinary form of intoxication indulged in by persons either voluntarily, for the pleasant and exhila- rating effect on the senses during one of its stages, or involuntarily, Jn consequence of a depraved appetite growing out of the former method. We see some men—and, unhappily, women also—who are seldom or never in a sober condition; others who im- bibe a little at all times, and get intoxicated whenever they are under undue excitement or depression ; and still others who " go on a burst" once every three, six, or twelve months, and in the mean time totally ab- stain from any of the intoxicants. To this class belong those individuals who inherit the tendency to inebriation. Alcohol, taken to a degree to produce sub-acute intoxica- tion, excites the vascular and nervous sys- tems ; all the secretions are at first arrested, and the temperature of the body is lowered, and not, as has been generally believed, in- creased. If taken by a person who is not accustomed to it, it occasions derangement of the stomach, and nausea and vomiting are the result. The principal effect, how- ever, is noticeable upon the nervous system. There is a general feeling of increased phys- ical power, and the mental faculties are ex- hilarated. The patient at first talks ration- ally, but is very verbose and grows confiden- tial. Incoherence follows upon this, and then delirium and sopor. The effect is also seen on the .cerebellum by the impairment of the power of co-ordination, causing at first the staggering gait, and ending in com- plete loss of muscular power. When this stage occurs the individual generally falls into a deep sleep, from which it is almost impossible to waken him. When conscious- ness is restored there is a feeling of depres- sion, which the patient seeks to relieve by a resort to stimulants. Little can be said of the palliative treatment of this variety of intoxication. With the exception of the employment of emetics to unload the stom- ach, and the administration of ammonia and tea as antidotes, the patient should be allowed to " sleep it off." (For the chronic effect of acro-narcotic poisons see Inebri- ety and Methomania.) Itch. See Scabies. Jail Fe'ver, a form of Typhus (which see). Jaun/dice. This is a greenish-yellow color of the skin which is produced by the presence of the coloring-matter of the bile in the blood. It is not a specific disease, as is gener- ally supposed by the laity, but a symptom, which, taken in connection with other symp- toms, points to the affection which gives rise to it. We might as well speak of vomiting, headache, etc. as diseases: they are not, but merely prominent symptoms of many varied morbid processes. If jaundice occurs in any great abundance, or persists for a length of time, we find all the secretions tinged with 02 THE FAMILY PHYSICIAN. the bile, the urine becomes saffron-colored, and the stools, being deprived of their coloring-matter, are whitish. We may have jaundice produced in two ways—either from suppression or retention of bile; the former is due to some disease of the liver which incapacitates it for performing its function; therefore the bile, which in the healthy state of the organ is constantly being filtered from the blood, accumulates in it. Jaundice from retention of bile is produced in this way: The bile, having been already formed, is prevented from making its way into the intestines by some obstruc- tion in the bile-ducts; it is therefore re- absorbed, and again makes its appearance in the blood. The obstruction to the ducts may be either external or internal. Exter- nally, we may have tumors of various kinds pressing on the ducts, as cancer of the pyloric end of the stomach, of the duodenum or the end of the pancreas, or a colon impacted with faeces. Internally the gall-duct may be plugged up by mucus, or, what is far more common, by a biliary calculus passing through it; this is accompanied by a great deal of pain; indeed, it is said to be the most severe pain that can be felt. Some idea of it may be had from a knowledge of the fact that the common bile-duct is very seldom larger than a goose-quill, and the stones which pass through it' are seldom smaller in diameter—sometimes attaining the size of a pigeon's egg. Accompanying the jaundice and pain in these cases we have nausea, vomiting, hiccough, flatulence, and in the intervals between the intensity of the pain the patient is exhausted and drowsy. There is generally much more pain felt by the passage of a calculus for the first time than subsequently, as the ducts are generally left distended for its successors. Besides the above forms of jaundice there is also a malignant form, which is analogous to typhoid, yellow, or remittent fever, and is marked by typhoid symptoms from the be- ginning of the attack, and is accompanied by haemorrhages from the mucous mem- branes and skin. It almost always ends fatally. In jaundice from suppression the urine only contains those ingredients of the bile which pre-exist in the blood—viz. the bile coloring-matter and cholesterine; in that from retention we also have the bile- salts which have been formed in the liver, and afterwards absorbed and eliminated by the kidneys. To determine the former, nitric acid is generally added; it produces a bright grass-green color with the coloring-matter of the bile. The bile-salts, however, can only be detected by Pettenkofer's test, which is as follows: To the suspected liquid add a few drops of a solution of cane-sugar, and I then slowly, drop by drop, sulphuric acid; [ at first a red color will be produced, which will afterwards change to a lake, and then to a deep purple. The technical name of jaundice is icterus, from the Greek name of the golden thrush, which, according to Pliny, when seen by a jaundiced person would die and the patient recover. Now, however, we treat the affec- tion more scientifically, looking to its origin. Where it is due to suppression little can be done except in cases of acute inflammation of the liver, but in those cases due to ob- struction there is more success with it. The indications are to improve the patient's gen- eral condition by a proper and nutritious diet. Fats of all kinds should be avoided, as they cannot be digested without the as- sistance of the bile. Next, we should attend to the constipation from which these patients almost invariably suffer; for this rhubarb, senna, and aloes are the favorites. Opiumi should be given to relieve the intense pain. After the removal of the obstruction we may hasten the disappearance of the jaundice, and the annoying itching which accom- panies it, by steam and alkaline baths. Joints, Diseases of. See Ankylosis, Hip- joint Disease, Synovitis, Housemaid's Knee. Kid'ney Diseases. See Renal Diseases. Laryngitis [from Gr. lapvys, "larynx"], an inflammation of the mucous membrane lining the larynx. It may be divided into acute and chronic forms. Acute laryngitis generally commences as an inflammation of the pharynx, which is afterwards com- municated to the larynx, although it does occur independently in the larynx itself. The cause is generally " a cold," or ex- posure to sudden changes of temperature, or it may be traumatic; and the symp- toms consist of hoarseness, a sensation of tickling and dryness in the throat, and more or less cough and expectoration. With ordinary care it subsides in a couple of days without any medical interference, or at most a warm bath followed by gentle diaphoresis. In very severe cases inhala- tions of infusion of hops may be used every two or three hours with decided advantage, but we should be very wary about making astringent local applications with a sponge or brush. Simple chronic catarrh of the larynx is usually a sequela of the acute form, or arises by extension of a similar inflammation of the pharynx and posterior nares. The symptoms are somewhat similar to those of the acute form, though not as well marked, and in addition there is an al- most constant hawking and hemming kept up by the patient to clear his throat from the continually accumulating mucus. In THE FAMILY PHYSICIAN. 63 the treatment of this, as in that of all in- flammations, the first indication is to re- move all irritation, and the patient should be cautioned against swallowing large masses of food at a time, or, what is a very com- mon practice in this country, partaking of very warm dishes, followed by large draughts of ice-water. All the food taken should be of equable medium temperature, neither too hot nor too cold, and the inhalation of hot and cold air and noxious vapors, dust, etc. should be avoided as much as possible. Besides all this, the general health should be by no means neglected, and local medica- tion seems to be very beneficial. Standard solutions of nitrate of silver, sulphate of copper, perchloride of iron, iodine, etc. are those most commonly used; they seem to produce a better result when changed from time to time, and the application should be made by means of a camel's-hair brush from twice to five or ,six times weekly. Laryngeal phthisis occurs in connection with pulmonary phthisis; the symptoms differ little from those of an ordinary la- ryngitis, but upon examination the carti- lages are found thickened, and often there is ulceration affecting both them and the cords. Syphilitic laryngitis exists as a manifestation of that dire affection, syph- ilis. It is principally from the previous history of the case and an exploration of the chest that we differentiate it from la- ryngeal phthisis. Sometimes the destruc- tion of tissue is appalling. In the latter two varieties the chief reliance must be placed on the constitutional treatment of the disease of which they are but symp- toms ; but still, local medication should not be ignored. In ulcerative laryngitis, from whatever cause, powdered iodoform seems to have the most beneficial effect. (See Throat Diseases.) Lead/-Poisoning, a diseased condition re- sulting from the presence of a considerable amount of lead in the system. This condi- tion is induced in various ways: (1) By the use of lead pipe for the conduction of drink- ing water. Happily, a large proportion of the waters used for drinking and cooking have not the power to take up lead in solu- tion, but there can be no doubt that a very great number of cases of lead-poisoning are induced in this way. (2) By the use of lead pipes in racking off wines, cider, and beer ; by the use of lead-lined chambers in soda- water apparatus and the like. It is very certain that the use of leaden siphons for drawing cider and vinegar from the cask is a very common practice among farmers and dealers in the FT. S.; and a dangerous, senseless, and even criminal, practice it un- doubtedly is. (3) By the use of lead paints; hence the name "painter's colic" applied to one symptom of lead-poisoning ; plumbers, type-setters, and operatives in white-lead works are often its victims. Symptoms.— These are (1) pain, often intense, in the ab- dominal region, with constipation, some- times, though rather rarely, accompanied by acute inflammatory symptoms; (2) a blue line visible on the gums near the roots of the teeth; the gums and teeth often foul and tender; the breath offensive, the mouth having a metallic taste; (3) sometimes icterus or jaundice—the skin dark rather than yellow; the patient usually looking pinched and haggard; (4) there is a certain proportion of cases which have "lead- palsy," affecting primarily the extensors of the wrist. This is the affection called "wrist-drop," though wrist-drop is some- times seen with no other indication of lead- poisoning. Lead rheumatism sometimes occurs, and disease of the brain from lead- poisoning, while delirium, convulsions, and coma are not unknown, but these forms are rare. Treatment.—Opium is the sheet-an- chor in ordinary lead-poisoning. It relieves the pain, and even at times the obstinate constipation of this disease. Cathartics are extremely useful, except when there is much tenderness of the bowels. In such cases their use should be deferred for a time. Iodide of potassium is prescribed in chronic cases, and is believed to assist in the elimin- ation of the metal. Sulphuric acid and the sulphates are administered with a view to precipitating lead from the circulation. Lep/rosy [Gr. Xerrpa, "leprosy"], "an in- curable constitutional disease of adult life, which is especially prevalent in tropical and sub-tropical climates." (Robert Liveling.) It may be divided into three forms, as fol- lows : "First. Macular leprosy, character- ized by an eruption on the skin, accom- panied by anaesthesia. Second. Anaesthetic leprosy, of which the chief features are anaesthesia and discolorations of the skin and atrophy of the muscles, with ulceration and mutilation of the hands and feet. The third form, or tuberculated leprosy, is cha- racterized by a bronzing and tuberculated thickening of the skin, especially of the face, ears, hands, and feet, followed by simi- lar changes in the mucous membrane of the upper part of the alimentary and respir- atory tracts, ending fatally in from two to fifteen years, by intercurrent disease in some vital organ." (Liveling.) Leprosy, or elephantiasis Grozcorum, is a disease which has been known and justly dreaded from the earliest ages. We find frequent mention of it in the Bible, but the disease as there spoken of evidently includ- ed many other skin affections, which at that 64 THE FAMILY PHYSICIAN. time they were unable to differentiate. The proof of this is that the cases are there men- tioned as having recovered, which we now know would have been impossible had they been true leprosy. The leper has always been an outcast from society, both on ac- count of the loathsomeness of his disease and the idea which has prevailed of its con- tagiousness. During the Middle Ages nu- merous leper-houses were established in various parts of Europe, where those suffer- ing from the disease were confined, and pro- hibited by law from appearing in the streets. Now, however, that it is known that the dis- ease can only be transmitted from parent to offspring, the laws are more lax on this point, and a leper-house is a thing seldom heard of. At the present time leprosy is most prevalent in Syria and Egypt, and the cases met with throughout Europe and America are rare. Almost every drug in the pharmacopoeia has been used in the treatment of this disease, but without avail, and now the treatment is principally palli- ative. Good food, clothing, and the pre- vention of marriage amongst lepers are the only means we possess to better their con- dition and decrease their number. Leucocythae'mia [Gr. Aevudg, "white," Kvrog, "cell," and dc/na, "blood"], or Leu- chaemia, a disease of the human subject, characterized by a very great excess of the white cells in the blood, and by a corre- sponding diminution of the proportion of red corpuscles. It is accompanied by en- largement of the spleen or of some of the lymphatic glands, or of both, and cases are reported accompanied by disease of the me- dullary mass in the bones, which mass takes on, or perhaps normally possesses, the lym- phatic function. In some cases the white blood-cells are not to be distinguished from the normal ones; in others they are smaller and accompanied by free nuclei and gran- ules. The liver is frequently enlarged. A haemorrhagic diathesis is often developed. The patient wastes away and becomes anae- mic. Of the causation* and cure of this disease nothing is known. It is always fatal, but often chronic. Leucorrhcea [Gr. Aevadg, "white," and 'peu, to "flow"], the "whites," a catarrhal flow from the vaginal or uterine mucous membranes. This disease is an exaggeration of the normal mucous secretion, and is often consequent upon a somewhat inflammatory condition of the mucous membranes. Rest, the use of iron and other tonics, and astrin- gent washes are often highly beneficial. Sometimes the catamenia assume a leucor- rhoeal character, especially towards the close. The cervix uteri is often involved in a sub- acute or chronic inflammation, which not unfrequently is best treated by local caustic or other applications. Lith/ic-Ac/id Diath/esis, a name given to that condition of the general system which favors the production of lithic acid or its salts in the urine. It has been, and still is by many, regarded as a peculiar diseased state in which the acid or its salts are pro- duced in the blood, and separated therefrom by the kidneys; but those taking an oppo- site view hold that the salts are formed in the urine, either in the pelvis of the kidney or the bladder, but always after it has been ex- creted ; also, that the peculiar condition of the system favoring it is one of mal-assimi- lation. Lithic or uric acid occurs in the urine as small crystals of an amber color, varying in diameter from ■5-03j31yt;li to x^th of an inch ; they are usually either lozenge or drum shaped. It may also exist in com- bination with ammonia, soda, or lime, form- ing the urates of those bases. The urates form the sediment generally found in the urine in nearly all acute inflammations, fe- vers, gout, rheumatism, diseases of the liver, etc., and they indicate a highly acid condi- tion of the fluid, by which they are precipi- tated from those substances which should hold them in solution. When deposited in any part of the urinary tract they may form into gravel or stone. (See Calculus.) Treat- ment should be corrective. The aliment has not been properly assimilated; in four cases out of five abuses at the table are the source of the trouble. Liver, Diseases of. See Ascites, Cal- culus, Colic, Gall-stones, Hepatitis, Jaundice. Lockjaw. See Tetanus. Locomotor Ataxia. See Tabes Dorsalis. Loss of Voice. See Aphonia and Throat, Diseases of. Lumba/go [Lat.], or Crick in the Back, is a sub-acute rheumatism, often very severe, and seated in the lumbar region. Strong liniments, rubbing with the hand, the ap- plication of the electrical brush, and cup- ping are all useful. Lung Fe'ver. See Pneumonia. Lu/pus [Lat., "wolf"], a disease of the human subject, most commonly attacking the face, and beginning in nodules in the skin. Sometimes this disease is observed in syphilitic or scrofulous patients, but in many cases no predisposing diathesis can be found. It usually attacks the young after puberty, and is rare after the age of forty. It is roughly divided into lupus exedens, or de- vouring lupus, and lupus non exedens, in which there is no ulceration; but in this last form there are sometimes neoplastic growths in the integument, which degener- ate and shrink away, horribly distorting the THE FAMILY PHYSICIAN. 65 face. There are many minor varieties known to the surgeon. True lupus, if neglected, becomes one of the most dreadful of dis- eases, destroying the tissues as completely, and often far more rapidly, than cancer. Happily, it is commonly a much less pain- ful disease, and it is so far local that if thor- oughly destroyed by caustics there is room for hope of permanent recovery. If the disease should return the application of the caustic must be repeated. Cod-liver oil, iodine applications, and general tonics are often useful. Mala'ria. See Intermittent Fever, Miasma, Remittent Fever. Malig/nant Diseases. See Cancer. Malig'nant Sore Throat. See Diphthe- ria. Malig'nant Pustule, a disease communi- cable from the lower animals to man (and especially from horned cattle), though some- times, apparently, originating in man with- out contagion. It is apparently the same as " black quarter " in neat cattle and " mur- rain " in sheep. It sometimes attacks those who handle the hides, and especially the hair, of the lower animals; and is believed to be sometimes propagated by insects, which, flying from the animal which is diseased, may alight upon some abrasion or pimple on the skin of a human subject, and thus transmit the disease. In its inception it resembles a boil, or sometimes a carbun- cle, seldom very painful; the pustule soon becomes the seat of gangrene, sometimes emitting a remarkable fetor; there is an intense fever, with profound septic symp- toms ; and unless active treatment be em- ployed death is certain to follow; which, indeed, is often the case with the best treat- ment. To be effectual the treatment should be undertaken early. But, unfortunately, it is often impossible to distinguish the disease early, unless it assumes a quasi-epidemic character, as sometimes happens. The use of powerful caustics upon the pustule, with general stimulants, tonics, and concentrated food, is sometimes effectual in saving life. Maras/mus, consumption of the bowels, abdominal phthisis, is a wasting disease of the entire body, dependent upon scrofulous or tubercular degeneration of the mesenteric glands. It is chiefly a disease of children, especially the bottle-fed, those in asylums, or illy cared for. It often coexists with the presence of tubercles in the lungs or tubercular meningitis, and frequently is de- veloped by the exhaustive influence of a difficult dentition or persistent summer diar- rhoea. The prognosis is always bad. The treatment is entirely nutritive. Fresh air, the seaside, abundance of pure milk, rich diet, cod-liver oil by the mouth and by in- unction, and tonics may save some cases. More often the emaciation is progressive, and the patient dies of exhaustion or in the coma and convulsions of associated brain trouble. The enlarged mesenteric glands can often be distinctly felt. Marks. See Birth-marks and N^evus. Mea/sles [Lat. morbilli], (Rubeola), the most frequent of the eruptive fevers. It is met with chiefly in the young (rarely in the first half year of life) and in such adults as have not contracted it in childhood. Most people are affected but once in a lifetime, but the cases of second, third, and even fourth attacks, are not uncommon. Its contagion is most effective about the time when the eruption first shows itself, but it remains active until the skin has been re- stored, by peeling (desquamation) and suc- cessive development, to its normal state. The eruption consists of small elevated reddish spots (like a raspberry), which merge into each other, and form discolora- tions of the size of a pea to that of a dime- piece, interrupted by normal white skin. In from eight to twelve days after contagion a number of premonitory symptoms develop, such as cough (loose or barking), languid eyes, nasal catarrh, headache, and fever. At the end of four days the eruption ap- pears, first on temples, forehead, and cheeks, progresses downward a day or two, and dis- appears in about four days. The skin will peel off in very small scales (not in flakes as in scarlet fever), and be in a normal condi- tion after a week. Meanwhile, the cough will become looser, the discharge from nose and bronchial tubes less, and fever subside. The large majority of cases run this mild and normal course with a very small mortality. But there are cases and epidemics accom- panied with great danger in consequence of complications. The main danger lies in the accompanying inflammation of the bron- chial tubes and lungs, which may prove fatal in a short time, or result in chronic inflammation and consumption. Besides these, inflammation of throat, ear (not so fre- quently as in scarlatina), eyes, and kidneys may remain behind. As these affections are very serious, every case, no matter how mild, ought to be seen once or twice by a physician. The usual treatment of mild cases consists in rest in bed from three to eight days, moderate darkness, and cool temperature (67-68° F.) of the room, cool- ing beverages. AVhere cough is obstinate a child of two years may take twenty-five drops of paregoric or one grain of Dover's powder at bed-time. In some cases there is a difficulty in regard to distinguishing measles from scarlet fever, especially where the former is also complicated with sore 66 THE FAMILY PHYSICIAN. throat of a simple or diphtheritic character. The ushering-in symptoms belonging to the respiratory organs, such as described above, are characteristic of measles, while scarlet- fever symptoms take hold of mouth, throat, and the digestive tubes in general. Meningi'tis [Lat. meninges, "membrane," and -itis, an affix denoting "inflamma- tion"], inflammation of the membranes which envelop the brain and spinal cord, termed cerebral, spinal, and cerebro-spinal meningitis according as the inflammatory process is limited to the region of the cere- brum or brain, the region of the cord, or involves the investments of both. Acute cerebral meningitis results from injuries of the head, as fractures and diseases of the cranial bones, inflammation and suppura- tion of the middle and internal ear, from excessive mental labor, from perverted states of the blood, as in typhus fever and acute rheumatism. Sub-acute or secondary men- ingitis, of less intensity, occurs in many of the febrile diseases. The tubercular men- ingitis of children is the result of mal- nutrition of the blood or of actual tubercle of the brain. Spinal meningitis most often follows injury or disease of the vertebrae, less frequently is excited by rheumatic, gouty, and tubercular blood states. It may occur, as among soldiers in the field, from exposure in sleeping on the ground. Cer- ebro-spinal meningitis is usually epidemic, and is but one manifestation of a malignant febrile disease, the cerebro-spinal or spotted fever. Acute meningitis is treated locally by cold applications and counter-irritants, internally by remedies reducing the action of the heart. In secondary meningitis we treat the primary disease, the exciting cause. Tubercular meningitis requires im- proved hygiene, diet, tonics, and altera- tives. Cerebro-spinal meningitis requires nourishing diet, tonics, and stimulants to resist the degenerated blood state, and opium is pre-eminent in curative effects. (See Brain Fever.) Menta'gra. See Barber's Itch. Methomania [from the Gr. yidv, "wine," and y.avia, "mania"], irresistible desire or morbid craving for intoxicating substances. (See Dipsomania, Inebriety.) Mias/ma [Gr. /niaaua, "stain," from fiialvsiv, to "contaminate"], an emanation, especially that from the earth in low marshy districts, which is capable of penetrating the human system, and producing therein certain mani- festations of disease. It probably consists of cryptogamic growths, the product of veget- able fermentation. It is never generated un- less the average temperature of the day is 60° F., and sometimes a much higher tempera- ture is required, as in yellow fever, which never occurs below 80° F. Another thing necessary for its production is moisture, hence we do not find it in dry or sandy regions. Besides these, it is essential that there should be vegetation; accordingly, we find it in the extensive marshes of warm latitudes, and not in high and cold regions. Exceptions to this rule may be found in the Dismal Swamp and in the bogs of Ireland, which do not produce it. New alluvial soils, when there is a subsoil of clay, are espe- cially adapted to its production. Miasmatic diseases may and do occur where miasm is not produced, as it may be carried from one place to another by rivers, and it seems to be more prevalent on the eastern than on the western bank. It is also found at the mouths of rivers. The drying up of an in- undation is apt to reproduce it where it has previously existed. It is formed about mea- dows that have been flooded for the purpose of cultivation. A wet season followed by dry weather is eminently productive of it, but a continuous wet season not so. In miasmatic regions turning up the soil will give rise to this poison in great abundance. In the excavation of the Erie Canal the fever was renewed in regions where it had ceased. Mill-ponds when low produce miasm. It can be conveyed by the wind over level surfaces for several miles. The circumstances which are unfavorable to the production of miasm are—1st, high lat- itudes and altitudes. Mountain-regions are generally free from this disease. Primitive forests are little subject to miasmatic affec- tions, but whether this is due to the shade or to absorption by the leaves is not known. Free ventilation diminishes the danger, and the more stagnant the air the more concen- trated will be the poison. Obstacles may be interposed to cut off the miasm. A screen of trees will very often preserve a house from malarious influence; this is true also of hills. Inundation appears to drown it out for a time, but as soon as the water disappears it returns. Cultivation of the soil while continued will drive away the miasm. The drainage of marshes is a pro- tective measure, although it requires some years to exhaust it. This is very strikingly illustrated in the drainage of large cities. Cold has the power of destroying it, and when miasmatic diseases occur in winter they are due to exposure during the pre- vious season. Certain plants growing in the marshes have the power of destroying it. Night adds to the power of the poison —day dissipates it. No point in the his- tory of miasm is probably better settled than this. It is known to be more active on the ground than on neighboring ele- i vations, and the upper stories of a house THE FAMILY PHYSICIAN. 67 are safer than the lower. Many persons suffer from miasm without having fever; these persons lack mental and physical power; the countenance is pale, and the period of life is shortened. The influence of the poison may be seen even in animals which are fat enough, but certain diseases of the viscera appear when they are pre- pared for market. Miasmatic fevers may return any number of times. Quinine will both cure and prevent them. (See Inter- mittent Fever.) Menierre's Disease. See Ear, Diseases of. Milk Fever, a name applied by midwives to a short febrile attack which sometimes attends the beginning of the milk-secreting process, a few days after childbirth. It is sometimes ushered in by profound and rather alarming chills, but is unimportant except as sometimes simulating the onset of puerperal fever, for which it is occasion- ally mistaken. Farmers and veterinarians apply the name to puerperal peritonitis of the lower animals, and to a severe form of cerebro-spinal meningitis which sometimes attacks cows after calving. The last-men- tioned disease is treated by cathartics, mer- cury, aconite, and heat to the spine; the former, by opium, aconite, mercury, and hot abdominal fomentations. Milk Leg. See Phlebitis. Mortification. See Gangrene. Mouth, Diseases of. Inflammation of the mouth is designated stomatitis. Simple sto- matitis or catarrh of the mouth results from the irritation of decayed teeth, of hot or cold food or drinks, of chemical or medicinal ir- ritants, and by using tobacco and pipes. It occurs in infants during dentition; they may cease to nurse, and the irritation of the sen- sitive nerves of the mouth may cause reflex spasm or convulsions. Its symptoms are a sense of burning, tenderness, tension, foul taste, the adherence of viscid mucus, and a diffuse redness. The treatment comprises the frequent cleansing of the mouth by cold water, alkaline gargles, as of carbonate of soda, and the correction of the known cause. Ulcerative stomatitis appears in points upon the tongue, the interior of the lips and cheeks, where mucous glands have been obstructed, swollen, and ulcerated, or in- flamed in the courses of catarrhal stoma- titis. Aphthae, or croupous stomatitis, pre- sent small white spots with red borders, known as canker, and erroneously termed blisters or vesicles. They contain no fluid. The white spot is a, fibrinous patch of in- flammatory exudation upon the mucous membrane. This soon is thrown off, leav- ing a painful excoriation. Aphthae occur most often among* teething children who are poorly nourished. The spots may be numerous and isolated, or coalesce in irreg- ular patches. Their treatment is by diet, correcting indigestion, and chlorate of pot- ash as a specific. Diphtheritic stomatitis or cancrum oris, sloughing inflammation of the mouth, results from salivation and from defective hygiene in asylums for orphans and foundlings or among soldiers in barracks. With modern hygiene it has become infre- quently contagious or epidemic. The first appearance of diphtheritic matter should be cleared away, chlorate of potash hero- ically employed, the patches cauterized with nitrate of silver, and the strength vigorously sustained. Scurvy causes stomatitis of vari- able severity. Nursing children contract primary syphilitic ulcers of the mouth from infected mothers or wet-nurses. Muguet or thrush, erroneously termed aphthae, is a para- sitic disease. It occurs in infants during the first month of life, and in adults only preceding death by slow, exhaustive disease. In these two states the mouth is much opened to the air, which dries secretion, and mastication is slow. The parasitic plant Oidium albicans gains entrance and attachment. It develops at first in white frosty patches on the tongue and sides and roof of the mouth. It consists of round spores and delicate filaments. Later, the patches are thick, curd-like, and yellow, due to fatty degeneration. The deposits should be removed and the exposed sur- faces kept clean and bathed with a solu- tion of sulphite of soda. Mumps [Dutch mumms]. This is one of the infectious and contagious diseases, and belongs to the same class with whooping cough, measles, scarlatina, etc. It is often met with when the two latter are prevailing. In some localities with a moist and cold climate it is very frequent (endemic). The principal sufferers are cbildren (mostly male) of from seven to fourteen years, but adults are not exempt. Its period of pre- paratory development (incubation) lasts from one to three weeks; its principal symp- toms are—moderate fever; pain on pressure over the region of the parotid gland, mostly of the left side (but of the opposite side also, and sometimes of both) in front of and below the ear; considerable swelling of that region and the whole cheek and chin; difficulty in deglutition and respiration, cor- responding Avith the amount of swelling; change of the voice; fulness of the head; and dizziness. In many cases the spleen and numerous lymphatic glands are also tumefied. In men the testicles and seminal glands, in women the ovaries, may also swell, and catarrh of the mucous membranes of the eyelids, nose, and mouth is not un- | frequent. The disease lasts from a few days 6s THE FAMILY PHYSICIAN. to a week; the swelling will subside grad- ually ; in some cases, bowever, the parts remain large and hard; in a few an abscess will form. The treatment is simple. Reg- ulate the diet, give less meat, more milk, gruel, fruit; vegetable acids (lemonade) or dilute muriatic acid (ten to fifteen drops in a tumblerful of water) as a beverage, mild purgatives (Rochelle salts, seidlitz powder, cream of tartar). The best local applica- tions are raw cotton and cold water; warm water or poultices only when an abscess has commenced to form. No internal treatment except quinine when the fever is high, and iodide of potassium when induration re- mains behind. It is understood, however, that such treatment ought to be under the superintendence of a physician. MyelFtis [Gr. pvEA6g, "marrow"], inflam- mation of the substance of the spinal cord. At the beginning of this century nearly all affections of the spinal marrow were classi- fied under the title myelitis, but some prog- ress has been made in separating these va- rious diseases. Our knowledge is, however, as yet very imperfect, and in the classifica- tion offered below there are doubtless some errors. Forms of myelitis may be best class- ified, according to the product of the in- flammatory process, into softening myelitis, purulent myelitis, hyperplastic myelitis, and degenerative myelitis, (a.) The first of these forms, softening myelitis, is closely allied to non-inflammatory softening (from throm- bosis, embolism, etc.), and it is probable that future researches will reduce the fre- quency of its recurrences. After death a small part of the spinal cord, usually a seg- ment involving all its columns and the gray matter, is found softer than usual, or even in a semi-fluid state, reddish or reddish-yel- low in color, sometimes white or yellowish. The substance of the spinal marrow is dis- integrated, and a microscopic examination shows the presence of altered nerve-fibres and cells, granular bodies, fatty detritus. The symptoms during the life of the patient consist in impairment or loss of the power of motion and of sensibility in all parts of the body below the softened spot. For ex- ample, a focus of myelitis in the middle dorsal region will cause paralysis of the lower limbs (paraplegia) and of the blad- der and lower bowel; a focus in the upper cervical region will produce palsy of the entire body except the diaphragm. The symptoms may be developed rapidly, with pain and spasm, loss of function being com- j plete in a few days, or during many months the patient complains of increasing numb- ness, loss of sensibility and power. The prognosis i^ worse in proportion to the acute- j ness and to the higher location of the focus. ] Treatment occasionally arrests the disease, but probably never cures it. (b.) Suppura- tive myelitis is exceedingly rare, and we do not know any symptoms which can serve to distinguish it from any acute myelitis. The purulent matter is collected in the shape of small abscesses, or purulent elements are found diffused among the nervous fibres and cells, (c.) Hyperplastic myelitis is relative- ly common, and is that which gives rise to the various forms of "sclerosis." The in- itial lesion in these cases is increased activ- ity and volume of the neuroglia or frame- work of the spinal cord, with consequent wasting of the nervous anatomical elements. Later, products of degeneration appear in the shape of granular and amyloid bodies. The affected portion of the spinal cord is found hardened, like boiled white of egg or soft cartilage; it is grayish or yellowish in color, and presents a translucent instead of the normal dead-white appearance. The microscope shows increased neuroglia, dis- integrating nerve-fibres and cells, granular bodies (especially around the blood-vessels), and amyloid bodies. Sclerosis of the spinal cord may be classified, according to its dis- tribution in the organ, into (1) striped scle- rosis, which may extend upward and down- ward in any of the columns—in the posterior columns producing the disease clinically known as locomotor ataxia; in the anterior or antero - lateral columns produce para- plegia, with loss of motion alone or chiefly; in the lateral part of the antero-lateral col- umns giving rise to contracture of the limbs. There may be (2) a limited sclerosis, involv- ing the several columns and the gray matter at any part of the spinal cord, producing a chronic paraplegia; and (3) nodular (or in- sular) sclerosis, sclerose en plaques, in which the disease affects a number of spots upon or in the spinal cord (and brain), the nod- ules being distributed in a wholly irregular manner. The symptoms produced by nodu- lar sclerosis are very irregular, depending upon the location of the first and of the largest nodules; there are observed loss of power and sensibility (rare) in the limbs, mental and sensorial symptoms, (d.) De- generative myelitis includes two principal forms: (1) a parenchymatous inflammatory (?) change in nerve-fibres or ganglion-cells; and (2) the changes which occur in the spinal cord in consequence of a lesion in the brain or in the spinal cord. Finder the first head are to be classed those changes in the anterior horns of the spinal cord which give rise to paralysis accompanied by wast- ing of the affected muscles, or to wasting of the muscles primarily; acute, sub-acute, and chronic spinal paralysis (infantile spinal paralysis, spinal paralysis with atrophy in THE FAMILY PHYSICIAN. 6(J the adult), progressive muscular atrophy, labio-glasso-pharyngeal palsy. The lesion consists in a clouding and granular disin- tegration of the ganglion-cells of the ante- rior horns, with some as yet ill-understood change in the substance in which they are imbedded. Occasionally this lesion involves the greater part of the anterior horns in a longitudinal way, and soon leads to death by asphyxia (acute ascending palsy). In some of these forms sensibility is relatively little impaired, in others not at all. The de- generative myelitis which is caused by some other lesion of the nervous centres consists in wasting of the nerve-fibres and the deposit of numerous amyloid and granular bodies. Myopia [Gr. pwj,tn "close," and ui/;, the "eye"], short-sightedness, due to excessive convexity of the cornea or to convergence of the visual axes of the eyes. It is pro- duced by excessive use and straining of the eyes, or impaired health and nervous excit- ability, which disorder the motor muscles of the eye, and the "accommodation" or tension of the eyeball, determining the convexity of the cornea. But the bad habit of holding books or other objects too near the eye, especially with children at school and with artisans, is the most frequent cause. It is to be remedied' by disuse or rest of the eye, corrected habits, and appro- priate glasses. (See Sight, Defects of.) Near-SighFedness. See Myopia. Nae'vus, points or patches of variable size on various parts of the surface of the body, of blue or purplish venous hue. These are often congenital, and are termed birth-marks, and frequently have a fanciful resemblance to persons or objects which appeared to or alarmed the mother previous to the child's birth. Such marks often present only dis- coloration, due to a venous capillary net- work, without vessels of perceptible size. Naevi, as a rule, are perceptibly vascular and elevated; they can be emptied of their blood by pressure with the finger, and again fill when the pressure is withdrawn. Naevi are treated by puncture with the white-hot needle, by caustics, compression, electroly- sis, styptic injections, and excision. Necro'sis [Gr. vinpuoic, a "killing"], the death of a large piece of bone or of a whole bone in the living subject, as distinguish- ed from caries, the ulceration or molecular death of bone. Necrosis may result from in- jury, from periostitis, from phosphorus- poisoning, and from syphilis. It may be superficial, central, or total. Necrosis almost always calls for surgical interference for its complete cure. The dead bone finally sep- arates as a sequestrum from the living bone, and until it is quite detached it is worse than useless to attempt to operate. The sequestrum is usually enclosed in a case of new bone, which must be cut through before the removal can take place. If the patient be young and otherwise healthy, the removal of the sequestrum is usually followed by re- covery. In all cases a generous diet, with appropriate tonic treatment, is called for. ' Nerv'ous Diseases, affections of the ner- vous systems, which are either organic or functional; i. e. diseases produced or accom- panied by an anatomical alteration which can be recognized with the naked eye or the microscope, and such as are caused by mor- bid states not accompanied by any such alterations. It is, however, probable that intimate chemical changes, not to be recog- nized with our present means of observation, occur in organs which are " functionally " diseased. The growth of physiological and psychological knowledge in the last few years has caused mental affections to be classed with nervous diseases. Besides these there are the following principal morbid states (many of which are treated of separ- ately in this work under appropriate head- ings) : anaemia, hyperaemia, mal-nutrition of the great nervous centres; hysteria, spinal irritation, epilepsy, chorea, neuralgia, teta- nus, catalepsy; inflammations of the brain, spinal cord, and nerves (and their enve- lopes); tumors and injuries of the same; apoplexy. It should be borne in mind that many nervous diseases, so called, are only expressions of general pathological states or sympathetic reactions to local morbid states of non-nervous organs. It has been taught that certain nervous diseases, such as insan- ity, hysteria, epilepsy, etc., become more fre- quent with increasing civilization. This is not fully established, and yet there can be no doubt that the strains of social life, the strug- gle for existence, the enormous striving of ambition, the intemperate use of sensual grat- ifications, cause the above diseases in a more or less direct manner. Nervous diseases—or, more exactly speaking, the liability to nerv- ous disease—are very easily transmitted from parents to their children, this being most strikingly shown in insanity, hysteria, epi- lepsy, neuralgia, apoplexy. An important factor in the development of nervous dis- eases is wrong education, the cultivation of the mental powers during the age of growth, not enough rest, and insufficient (especially fatty) food being allowed. The evil effects of school-life are seen in both sexes, though perhaps more often in the female. Mens sana in corpore sano is not a mere adage, but a physiological truth. (See articles on special nervous diseases, viz., Apoplexy, Brain Fever, Catalepsy, Chorea, Concussion of the Brain, Cruveilhier's Disease, Delirium Tremens, Duchenne's Dis- 70 THE FAMILY PHYSICIAN. ease, Epilepsy, Facial Neuralgia, Fa- cial Paralysis, Hemiplegia, Hydro- phobia, Hysteria, Infantile Paraly- sis, Lead-Poisoxing, Meningitis, Meth- omania, Myelitis, Neuralgia, Neu- ritis, Paralysis, Paralysis Agitans, Paraplegia, Progressive Muscular Atrophy, St. Vitus's Dance, Scriven- er's Palsy, Spinal Diseases, Stupor, Sunstroke, Tabes Dorsalis (locomotor ataxia), Tetanus, Vertigo.) Nettle-Rash, or Hives [Lat. urticaria], con- sists of elevations of the skin of the size of a pea or a bean, or larger. These elevations are usually white, or white with a red centre, or white with a red margin, or red or white with a small vesicle in the centre. The dis- ease is of an acute character; the elevations spring up quite suddenly, and disappear after hours or days. Frequently they re- turn ; some people do not get rid of the pre- disposition to them for many years. The anatomical condition of the skin is that of an inflammation with effusion. The cause of this is either external or internal. Ex- ternal causes are contact Avith nettles, the influence of insects, a hot bath, the sun. In predisposed persons gentle pressure with the finger, friction, or slight irritation, suffice to produce it. Internal causes are such as irritate the nerves of the digestive organs, the genito-urinary organs, or the blood-ves- sels ; certain articles of food, such as cham- pagne, beer, sausage, strawberries, raspber- ries, currants, oysters; medicines, such as quinine or cod-liver oil. A general irrita- bility of the nervous system may produce it. Not infrequently, therefore, it sets in with fever, sometimes with a chill, always with burning and itching. The treatment is sim- ple, but not always efficient. Locally, the use of glycerine, cold-cream, mild solutions of carbolic acid in water. The diet must be regulated—no coffee, spice, beer, not much meat. The stomach must be improved by alterative treatment or bismuth or muriatic acid, according to circumstances. Mild pur- gatives will be beneficial. NeuraFgia [Gr. vevpov, "nerve," and dlyog, "pain"]. Pain in the course of a nerve is a symptom of many morbid conditions. The track and distribution of a cerebral, spinal, or visceral nerve may be the seat of the pain, which is sharp, occurs in par- oxysms repeated at intervals of a few seconds or a day, the pain between the aroxysms disappearing or being replaced y soreness or dull pain. The suffering is often very intense. One curious feature of neuralgic pain is its occurrence on one side of the body only at any one time. Usually no redness or inflammation is visible in the affected region, though an exception to this I rule is observed in neuralgia of the face, during attacks of which the eye is red and lachrymose. The parts which are the seat of pain are usually over-sensitive during the paroxysms, and numb between them; there may even be loss of sensibility. Along the track of the affected nerve one or more ten- der points are usually found. Neuralgias are divided (1) on the basis of their distri- bution, (2) on the basis of their causes. The former, or topographical classification, includes the following varieties among others: facial, occipital, brachial, inter- costal neuralgia, sciatica. According to the second or aetiological classification, there are—malarial, gouty, anaemic, hys- terical neuralgias; neuralgias from injuries to nerves, from inflammation of nerves, and from disease of the nervous centres. Be- sides, in the present state of science, there are cases of neuralgia for which no cause can be made out—idiopathic neuralgia. The rational treatment of neuralgia con- sists in treating the pathological' states which cause it. For the immediate relief of neuralgic pain the best remedies are (1) the external application of the hot-water bag, chloral-camphor, oil of peppermint, aconitine ointment, and lotions containing aconite, opium, and chloroform, and in some cases local leeching or blistering; (2) the internal administration of anodynes, as chloral, opium, belladonna. Electric cur- rents give immediate relief in many cases. IMeurFtis [Gr. vsvpov, "nerve"], inflamma- tion of nerves. Neuritis may be localized, but tends to extend above and below the starting-point; it may lead to myelitis. Peri-neuritis is that form of inflammation of nerves in which the general sheath of the nerve and the circumjacent connective tissue are the seat of trouble. The nerve appears to the naked eye larger, reddened, oedematous, and may be unnaturally fixed in its bed of connective tissue. The causes of peri-neuritis are partly unknown; cold may cause it, as well as injuries, and it is possible that the gouty disposition produces it. The symptoms of neuritis are pain, numb- ness, loss of function, expressed by paralysis and anaesthesia. Nose-Bleed (technically, Epistaxis). It is usually due to a ruptured vessel of small size on the mucous surfaces of the nostrils. It may occur where the nostrils have been thinned or eroded by the bad habit of pick- ing the nose, by the erosion of the surface > by catarrhal ulceration, or by a determination j of blood to the head, inducing rupture of a vessel. The hitter occurrence is the result of a too full habit, an excited circulation as in active children, or from excitement, vio- lent exercise, or overheating by the sun, and THE FAMILY PHYSICIAN. 71 of hypertrophy and dilatation of the heart. Nose-bleed also results from blows on the nose. It occurs in typhoid fever and other low diseases, where the blood is depraved. Nose-bleed is to be checked by rest on the back, cold to the nose, the use of cold water, tannin and cotton in the nostrils; when severe a physician should be called to plug the nostrils from the mouth. Nostrils, Diseases of. The nostrils or nares are divided into the anterior nares, which can be seen by external inspection of the openings of the nose, and the pos- terior nares, to be seen only by aid of small circular mirrors placed in the back of the throat to reflect light, admitted through the mouth, to the nasal cavities above. The most common of their diseases is catarrh. Nasal catarrh is produced by cold air, by insufflating dust, or by irritants. It is the beginning of many cases of laryngitis and bronchitis. It is the chief catarrhal condi- tion in influenza, in which disease catarrh extends through the nasal ducts to the eyes, the Eustachian tubes to the ears, and into the frontal sinuses. Simple recent nasal catarrh produces a watery, alkaline serum. When more pronounced the catarrhal flow is less serous, contains mucous corpuscles, and is viscid or even tenacious—is yellowish and purulent in color. Chronic catarrh may result in constriction of the anterior nares, in the development of exuberant granulations, and polypus. In the posterior nares, by extension to the throat, it more often results in permanent or obstinate naso- pharyngeal catarrh. Such chronic catarrh may give rise only to habitual coughing and hawking of mucus, but it often impairs the hearing by tumefaction at the aperture of the Eustachian ducts or by extension to the middle ear. Nasal polypus is an attached tumor in the nostrils, originally a small pro- jecting mass of granulations or enlarged glandular tissue. When chronic nasal ca- tarrh has resulted in ulceration and death of the cartilages or bones of the nose, the discharge is often offensive, and is known as ozaena. Close examination will discover particles of necrosed matter. Ozaena is more often the result of nasal catarrh in strumous, tubercular, and syphilitic persons. Epistaxis or Nose-Bleed (which see) is the result of local causes, as irritating or pick- ing the nostrils; it is a frequent occurrence in persons having disease of the mitral valve of the heart; it is a symptom peculiar to typhoid fever; it is often due to excessive exercise and to excitement. The catarrhal diseases of the nostrils are treated by topical applications, inhalations, and sprays. Ozae- na demands the insufflation or injection of antiseptic washes or the surgical removal of dead bone. Polypus is removed by cut- ting or tearing. Nose-bleed is checked by cold applications on the nose, by plugging the nostril with lint, or the introduction of styptics, as tannic acid, pernitrate and per- sulphate of iron. In extensive bleeding from the nose the nostrils have to be plugged from behind. Obes/ity [Lat. obesitas; synonyms, Poly- sarcia, Corpulence], an abnormal deposit of adipose tissue under the integument and around the viscera. The amount of adipose tissue in the organism may be considerably augmented without giving rise to any incon- venience on the part of the individual in the way of encumbering his movements or interfering with the functions of the viscera, etc.; but such a condition would not come within the scope of this article. It is still a condition of health, and the term obesity should only be applied to those cases where the deposit of fat is so great as to incommode the patient. Of the causes of obesity we may mention, first, hereditary susceptibility. It is not at all uncommon to meet certain families in which most of the members are corpulent, and sometimes the tendency to become so may be traced through several successive generations. Inactivity and se- dentary occupations exert a very material influence over the production of fat, es- pecially when combined with a rich diet. In women the predisposition to corpulence exists in the first years of child-bearing, and again after the " change of life;" in men, between the ages of forty and sixty. The exciting cause is generally found to 'be mal- assimilation, due to some derangement of the digestive organs. We mostly find it in individuals who indulge in a rich diet, and especially if it contains fatty matters. Ar- ticles abounding in sugar and starch and alcoholic and malt liquors seem to favor the production of fat to no inconsiderable ex- tent. The symptoms of obesity may be enumerated as follows: Diminution of men- tal and bodily activity, impeded action of the viscera, the organs of respiration, circu- lation, and digestion. The slightest exer- tion will bring on panting; the blood is comparatively deficient in quality and quan- tity, and, as a result, the muscles become ; weak and flabby. The countenance becomes | bloated and sallow, and the patients are j liable to suffer from a variety of affections which depend on mal-assimilation, as gout, rheumatism, etc. Often fatty degeneration of the heart or liver coexists, and we then have the symptoms of these maladies super- added. Mr. Harvey has shown, in his late work on corpulence, that the senses of hear- ing, taste, smell, or sight are often absent altogether or blunted to a very annoying 72 THE FAMILY PHYSICIAN. extent in corpulent persons. In the treat- ment of obesity alkalies internally and al- kaline baths have long occupied a promi- nent place, and even at the present advanced stage of medical science we hear physicians daily prescribing small doses of soda, po- tassa, etc. with a view to procure a saponi- fication of the fat in the interior of the body. Such a course of treatment is simply ridiculous. If a jockey wishes to " condi- tion" a horse that has acquired too great a deposit of adipose tissue, the course he adopts is a well-known one, and is pursued also by professional pedestrians, gymnasts, etc. It consists of a regulated diet and sys- tematic exercise in the open air. The case of corpulence treated successfully which has gained the greatest notoriety is that of Mr. Banting. He adopted a regular course of dieting, in which there was an absence of fatty, starchy, and saccharine matters. This should be rigidly adhered to, and in addi- tion no alcoholic or malt liquors should be partaken of whatever. Both body and mind should be exercised daily. Odontalgia. See Toothache. OphthaPmia [Gr. bscopy). The movements of the vocal cords are displayed best by phonating a (eh). All of these several connecting parts of the throat are richly supplied with blood-vessels, lined by a mucous membrane, secreting mucus. They are therefore liable to hypersecretion of mucus, or catarrh, which may be acute, subacute, or chronic; to active and passive congestions, inducing redness, heat, and swelling; to active inflammations, with for- mation of submucous abscess, erosion of the epithelial covering of the mucous membrane, or ulceration and sloughing of its deeper layers. Such destruction of soft tissue may induce necrosis of the underlying hard struc- tures, the nasal and laryngeal cartilages. Inflammation may terminate in an exuda- tion, developing organized membranes, as those of croup and diphtheria. Repeated congestions and inflammations tend to en- gorge and hypertrophy the structures of the mucous membrane and glandular bodies em- bedded in it. The papillae of the back of the throat and of the columns of the fauces are very often thus enlarged. The surface is seen to be studded with prominent ovoid papules or tubercles, a condition known as ' clergyman's sore throat," and technically as " papular pharyngitis." Polypoid growths of variable size develop in the nares, pharynx, and on and around the vocal cords—prod- ucts of papular growth and of granulation process. A most alarming and critical condition is acute oedema of the glottis. The secretion of the region of the larynx being suddenly checked, as by cold, or the seat of sudden determination of blood, serum transudes from the overloaded blood-vessels into the loose submucous connective tissue, and cre- ates a sudden dropsy and tumefaction. The distended, swollen structures overlap the opening of the glottis, and occupy the ven- tricles of the larynx, preventing inspiration, and threaten immediate death by suffoca- tion. The laryngoscopic mirror definitely locates the seat of these dropsical sacs, and is the sure guide to efficient scarification and evacuation of their contained fluid. The vocal cords may be affected by spasms, producing hoarseness, aphonia, and labored respiration, in which case the mirror detects the unusual approximation and irregular action of the cords, and excludes the pres- ence of more serious inorganic disease. One of the vocal cords may be found par- alyzed, inactive, and relaxed, while the other remains normal. Such paralysis of a cord may be due to vocal inflammation or abnormal growth, or may depend upon le- sions of the recurrent nerves in the neck, or again, coexisting with paralysis of one-half of the body, depend on a lesion of the brain —softening, embolism, apoplexy. Ulcera- tion or inflammation may so seriously dam- age the vocal cords that cicatricial or scar- like tissues are formed, tending to contract and harden; in time the chink of the glottis becomes contracted and narrow — termed "stenosis of the larynx." The aperture being no longer adequate for the ingress or egress of air, gradual suffocation must ensue unless surgical relief is afforded. Extensive destruction of the vocal cords often occurs from syphilis and epithelial cancer. The more accurate diagnosis of throat diseases, and intelligent study and classi- fication by aid of laryngoscopy, have led to corresponding progress in treatment. Ap- plications are no longer applied at random by probangs, uncertain of the condition that exists and of the parts which are reached. Remedies are applied with accuracy by va- rious methods, with definite regard for the indications of each case. Astringents—as cold water, alum, tannin, tincture of iron, and solutions of nitrate of silver—are em- ployed to contract blood-vessels, lessen con- gestions and relaxations of surfaces. Caus- tics are used to remove papular and granular developments, and induce absorption of hy- pertrophied structure. Local applications are made to heal ulcers. Inflammation is checked, limited, and cured by warm solu- tions and vapors impregnated with salts of soda, ammonia, and potash, or in other cases by cold gargles or spray. The salines tend to increase and liquefy the secretions of the throat; resin oil and astringent agents lessen them; carbolic acid, chlorine, etc. disinfect them when septic. Anodynes are given to allay pain, either by the stomach or locally. Electricity is applicable directly to the par- alyzed vocal cord. The knife is constantly of service in treating throat diseases, for the excision of the tonsils and uvula, opening abscesses, the incision of hard papules, pre- ceding use of caustics, removal of polypi, the scarification of oedema of the glottis, and for the operations of tracheotomy and laryn- go - tracheotomy, whenever, by congestion, inflammation, ulceration, stenosis, tumors, cancer, sudden oedema, croupous or diphthe- ritic membrane, or whatsoever obstruction, the larynx is closed to the passage of air and death is imminent by suffocation. ThronFbus [Gr. 6p6u[Jog, a " clot"], in pa- THE FAMILY PHYSICIAN. 113 thology, designates the fixed venous blood- clot Thrombus often accompanies phlebitis. It is conceded that dilatation or contraction of a vessel or great weakness of the heart's action, may favor the formation of thrombus. Thrombi are liable to putrefactive changes, whence follow metastatic abscesses and a long train of deplorable consequences. When thrombus exists, a rich diet, tonics, and pure air afford the only prospect of recovery. Thrush. See Mouth, Diseases of. Tic Douloureux. See Neuralgia. Tongue, Diseases of. The tongue may be inflamed from various causes, as hot drinks and irritants. It is often the seat of apthae, ulcers, "cancers," the result of catarrh of the mouth. The "coated tongue" may be due to a relaxed, flaccid, and pale condition of the papillae, and when notice- ably coated has an accumulated stratum of thickened saliva and rapidly exfoliated epi- thelial cells; the yellow color the result of the fatty metamorphosis which the cast-off cells speedily undergo. When the stomach is in- flamed or irritable, the papillae of the tongue will often appear as distinct points. The tongue is occasionally attacked by epithelial cancer. Ranula is a cystic tumor beneath the tongue, due to occlusion of some one of the sali- vary ducts. When any part of the tongue is the seat of motor paralysis, loss of sensation or taste, the part so deprived may be experi- mentally defined, and a study of the nerve- supply of the tongue will point to the part of the brain in which the lesion exists. Ex- ceptionally, in infants the "fraenum" or fib- rous cord beneath the tongue is too short; the "tongue-tied" infant cannot nurse well, and when older speaks imperfectly; the cure is by cutting. Tonsillitis. See Quinsy. Tooth/ache may be due to diseases of the dentine of the tooth itself—caries, ostitis, exostosis; to congestive inflammation or disease of the nerve in the tooth; to inflam- mation of the gums and alveolar processes or bony sockets of the teeth, with or with- out more general disease of the upper or lower jaw, as when fractured or affected by scrofula, syphilis, or phosphorus; to simple nervous debility or disorder, as from emo- tional causes, excitement, fatigue; to gen- eral blood states, as in invalids from any cause, especially phthisis, anaemia, and ma- laria. The cause of toothache should, if possible, be discovered. It is usually due to diseased teeth, which should be filled or extracted. Abscess of the gums should be incised. When purely neuralgic, improved diet, out-of-door life, and tonics are indi- cated. Malaria demands quinine; anaemia, iron; struma, cod-liver oil. The nervous cases yield to opiates, sedatives, and ner- vines. For the immediate relief of tooth- ache local leeching, cupping, poulticing, fomenting, lotions of chloroform, lauda- num, and aconite, embrocations of oil of peppermint and chloral camphor, and the use of opiates, chloral-bromides by the mouth, are useful measures. ToxicoFogy [Gr. to^ikov, "poison," and Aoyog, " discourse," a treatise on poison]. Poi- sons are classified with reference to their source, as (1) animal, (2) vegetable, (3) mineral, and also with reference to their method of action: (1) corrosive and irritant poisons, such as corrode or inflame the stomach; (2) narcotic and sedative poisons, which, being absorbed by the mucous mem- brane, enter the blood and act on the nerve- centres. The corrosive poisons are—1. Acids —oxalic, hydrochloric, sulphuric, nitric. 2. Strong alkalies—ammonia, caustic potassa, and soda; alkaline earths—baryta and lime. 3. Metallic and other bases and their salts— corrosive sublimate, arsenic, sulphate of cop- per, tartar emetic, acetate of lead (sugar of lead), sulphates of iron and zinc, nitrate of silver, phosphorus, iodine, creasote, carbolic acid. The narcotic and sedative poisons are chiefly opium, belladonna, stramonium, hyoscyamus, aconite, digitalis, veratrum, tobacco, lobelia. Chloral hydrate is anaes- thetic and depressant in large doses. Hy- drocyanic acid depresses the heart or is im- mediately fatal. Strychnia and nux vomica act specifically on the nervous system, causing muscular rigidity and spasmodic contrac- tions. Poisons are often taken with suicidal intent, by accident, as by children or by adults erroneously as medicine or drink, and when carelessly dispensed by druggists, as oxalic acid instead of salts, morphia or strychnia instead of quinine. The symptoms of poi- sons are chiefly extreme disturbance of the stomach, the breathing, and the pulse, often with impairment of sight and great bodily weakness, pallor, and cold surfaces. Corro- sives and irritants cause burning pain in the stomach. Antidotes for poisons should be given im- mediately, while waiting the arrival of a physician. For poisoning by acids give alka- lies, solutions of soda, potassa, lime, ammo- nia ; afterwards white of eggs and sweet oil to soothe the stomach; for poisoning by alkalies give dilute acids, as vinegar or lemon-juice, and olive oil, which unites with the alkalies to form a soap and renders them inert; for corrosive sublimate, white of eggs and wheat flour; for arsenic, the hydrated peroxide of iron, kept by most druggists and many physi- cians. It can be made by adding aqua am- monia to liquor ferri-persulphatis, or even to common tincture of iron; the resulting pre- cipitate is to be used in tablespoonful doses. 114 THE FAMILY PHYSICIAN. The new dialyzed iron is a ready and efficient antidote ; magnesia may be used if no other remedy is obtainable. For sulphate of copper, white of eggs, milk, flour; for tartar emetic, oak-bark, tannin; later, opium to allay pain in the stomach. For sugar of lead (acetate of lead), sulphate of magnesia, making an inert sulphate of lead in the stomach and system; for sulphate of iron (copperas) and sulphate of zinc, bicarbonate of soda, freely given ; for nitrate of silver, common salt, free- ly given, converting it to chloride of silver; for phosphorus, a mustard emetic; later, opium and ice to quiet the stomach; for iodine, boiled starch; for creasote and carbolic acid, olive oil and white of eggs. In opium poi- soning, (opium, laudanum, morphine, pare- goric), emetics, as sulphate of zinc or cop- per, the stomach-pump, frequent draughts of strong coffee, constant exercise, as walk- ing to prevent sleep, belladonna by the mouth, atropine hypodermically, and the electric battery to the diaphragm and chest to keep up breathing ; for belladonna, opium ; for stramonium, hyoscyamus, aconite, digitalis, veratrum, tobacco, and lobelia, alcohol freely, to restore the pulse ; for chloral hydrate, alco- hol and the electric current. Hydrocyanic acid is usually instantly fatal; in small doses it depresses the pulse, and alcohol is the rem- edy. Poisoning by wild fruit and berries is usually due to the sedative effect of their juices, and demands vomiting, and alcohol to sustain the heart; so also in poisoning by the flesh of pigeons or game which has fed on wild berries. Strychnia (and nux vomica) i poisoning requires inhalations of chloroform and chloral by the mouth or hypodermically. TrichFna Spiralis, a parasitic nematoid worm infesting the muscular tissue of the {)ig, the rat, and some other animals, and iable to occur also in man. As commonly found, this worm is a quiescent encysted parasite, occupying, often in great numbers, the tissue of the voluntary muscles. The cysts are oval in form, more or less shuttle- shaped or pointed at the two extremities, lying between and parallel with the muscu- lar fibres, about u\jth of an inch long and Tcuth of an inch wide. 'When of recent origin, they are quite transparent and color- less, and hardly discernible by the naked eye; after a certain period they become partly opaque from the deposit of calca- reous matter, and are then visible as minute whitish specks scattered through the muscu- lar tissue. The worm lies perfectly free in the cavity of the cyst, coiled upon itself in a spiral manner, from which circumstance its specific name is derived. When stretched out it is of a tapering, cylindrical form ^th of an inch long, jjsjjth of an inch thick in its widest portion. Its posterior extremity is blunt and rounded, but the anterior half of the body tapers gradually from behind forward, and is comparatively slender. The mouth and anus are situated respectively at the anterior and posterior extremities, and the intestine runs in a direct line from one to the other. The sexes are separate, differ- ent individuals being either male or female, but the sexual organs are incompletely de- veloped, and do not exhibit any functional activity. The worm often moves distinctly while still in the cavity of the cyst, the movements consisting of occasional slug- gish, partial flexion and extension of the two extremities. In this imperfect and practically sexless condition the parasite may continue for an indefinite time, retain- ing its vitality, but undergoing no percepti- ble change. When, however, a portion of trichinous flesh is devoured in the raw state by man or certain kinds of inferior animals, the muscular tissue and the encysting cap- sules are liquefied by digestion, and the worms are set free in the cavity of the in- testine. Here they at once increase in size, and in about two days become developed into mature and sexually perfect trichinae. The sexes are now readily distinguishable from each other. The male is ^th of an inch long, with a folded spermatic tube occupying the posterior half of the body, and terminating externally at the anus, where it is provided with two projecting conical copulatory appendages. The female is half as long again as the male, and nearly the whole of its posterior two-thirds is oc- cupied by the ovarian tube, which contains the eggs, and which terminates in an exter- nal orifice or vulva, at the anterior fifth of the body. At this time fecundation takes place by union of the sexes, and the female, at the end of seven days from the introduc- tion of the trichinous food, begins to pro- duce living embryos, which are discharged successively from the vulva into the sur- rounding cavity of the intestine. The pro- duction of these embryos is very abundant. According to Pagenstecher, it is often pos- sible to count 500 or 600 at one time, fully formed or in process of development, in the body of a mature female; and as the gene- rative act continues for at least a week or ten days, it is possible that each female trichina gives birth in the intestine to 1000 or 2000 living young. The embryos, when discharged from the body of the female, are rather less than vjfojth of an inch in length, nearly straight, and tapering somewhat toward the anterior extremity. They immediately begin to pen- etrate the walls of the intestine and disperse themselves over the body. They have been found under these circumstances in the sub- THE FAMILY PHYSICIAN. 115 stance of the intestinal walls, in the mes- entery, the diaphragm, the peritoneal and pleural cavities, and thence outwardly in all the voluntary muscles of the trunk and limbs. Their passage takes place quite rap- idly, as they may be found in the diaphragm of the rabbit on the eighth to the thirteenth day after feeding with trichinous food, and on the fifteenth or sixteenth day in the mus- cles generally. On their first arrival in the muscular tissue they are apparently quite free, and capable of moving slowly from one point to another; but they soon afterward become enveloped in a closed capsule or cyst, and there grow to a larger size. As they increase in length within the confined space of the cyst, they become gradually coiled up, thus assuming the spiral form characteristic of the encysted worm. They are then shut off from immediate contact with the surrounding tissues, and pass at once into the quiescent condition. This process of the development of adult trichinae in the intestine and the dispersion of their young throughout the system pro- duces in man and animals a severe and often fatal illness, known as trichinosis. Its earli- est symptoms are those of intestinal irrita- tion, caused by the growth and activity of the ingested worms — namely, abdominal pains, nausea, vomiting, and diarrhoea. There is also fever and loss of appetite. Then fol- lows an oedematous swelling of the face, body, and limbs, with muscular pains and tenderness, especially on motion ; so that the patient lies helpless, with the arms and legs in a semiflexed position, and any attempt at either active or passive movement causes suffering. This corresponds with the period of dispersion of the embryonic worms and their establishment in the muscular tissue. There is also marked difficulty of chewing and swallowing, owing to the invasion of trichinae into the corresponding muscles; hoarseness or loss of voice, due to their pres- ence in the laryngeal muscles; and even in some cases serious disturbance of respiration, from a similar affection of the diaphragm and the intercostals. The fecundity of the adult worms, and the abundant emigration of their embryos into the muscular system, are fully sufficient to account for these symp- toms. In man, after death from trichinosis, there have been found in the same subject in the gastrocnemius muscle of the leg 30,000 young trichinae to the cubic inch; in the biceps muscle of the arm, nearly 70,000; and in the deltoid muscle at the shoulder, over 90,000 in the same space. The severity of the disease, other things being equal, is in direct proportion to the quantity of trichinous food ingested and the number of living para- sites which it contained. In severe cases death may take place within the first two days, from the intensity of the diarrhoea and febrile disturbance. More commonly, the fatal termination occurs in the fourth or fifth week. If the patient survive this period, the chances of recovery are much increased, as the parasites have then become encapsuled and are passing into a state of quiesence. When this is accomplished, the morbid symp- toms gradually subside, and the patient is restored to a comparatively healthy condi- tion. The encysted trichinae, however, re- main imbedded in the muscular tissue for very long periods, and it is not known whether they ever entirely disappear. They have been found in a man eighteen years after the attack produced by their invasion. The source of this infection for man is almost invariably trichinous pork; for al- though the rabbit, the cat, the rat, the mouse, j the sheep, and the calf are all susceptible to the disease, as proved experimentally by feeding them with trichinous flesh, yet in the sheep and calf it is only exceptionally I produced under these circumstances, and never shows itself spontaneously either in them or in the rabbit. It could not be pro- duced in any of the birds experimented on by Pagenstecher—namely, the common fowl, the turkey, the pigeon, and the goose—nor in frogs or newts, nor in several species of invertebrates. The only animals in which it occurs spontaneously and frequently are the rat and the pig; and the latter has been the source of infection for man in every in- stance thus far known. The disease, as af- fecting the human subject, is most frequent in Germany, owing to the habit among cer- tain parts of the population of eating ham, sausages, and even fresh pork, in an uncooked condition. Within twelve years after the first recognized case, which happened in Dresden in 1860, there were eleven recorded well-marked local epidemics, of which the most disastrous was that at Hedersleben in 1865, where, out of 2000 inhabitants, over 300 were taken sick and 101 died. In the U. S. it is rare, occurring mainly in isolated cases or among members of a single family who have partaken of the same food. The danger of infection by trichinosis con- sists in taking as food pork which is imper- fectly cooked. The fat of pork is not inju- rious in this respect, as the adipose tissue never contains trichinae. But the muscular flesh in any of its varieties, as fresh pork, ham, sausages, or the lean parts of bacon, is liable to produce the disease. The pig from which the meat is taken may have long since recovered from the original attack, present- ing a perfectly healthy appearance when brought to the slaughter-house, and the parasitic cysts are usually too minute and 116 THE FAMILY PHYSICIAN. transparent to attract the attention of the butcher or the provision-dealer. Neither pickling nor smoking, as ordinarily practised, will destroy the vitality of the trichinae, and they may be found still living in ham or bacon cured by either process. The only protection is that afforded by thorough cook- ing. The trichinae are killed by a tempera- ture of 160° F., and meat which has been subjected for a short time to this tempera- ture is harmless. Care must be taken, how- ever, that all parts of the meat used be heated to the requisite point, otherwise it is as dan- gerous as if the whole of it were taken raw. A ham, if boiled for a short time, may be raised to a much higher temperature than 160° on the outside, while its internal parts are still below that point; and fresh pork which has been roasted or broiled may be thoroughly cooked externally, but still red and juicy within. The only safe rule to fol- low is that the fresh meat should be broiled or roasted until its color is changed through- out, and that for hams the boiling should be continued until the internal parts are perceptibly softened as well as the exterior. Since, in some instances, trichinae have been found in pigs slaughtered for the market in so large a proportion as 1 in 50, these pre- cautions are indispensable for protection from the disease. A further consideration of importance re- lates to the source of infection for the pig itself. Since this is practically the only animal from which man contracts the dis- ease, if trichinosis could be prevented or extirpated in the pig, the human subject would also be free from it. But as the en- cysted muscular parasite, whether in man, the pig, or the rat, is always quiescent and sexually unproductive, it is not fully evi- dent how the continuation of its species is provided for. No doubt rats are often con- taminated by each other, since they are well known to eat each other's flesh when de- prived of ordinary supplies of food; and the cat is naturally infected by devouring rats and mice. But as the pig neither feeds upon human flesh nor habitually upon rats, it is not easy to see why the affection should be so frequent among swine, or how it is perpetuated and transmitted from one to the other. There are probably two modes in which this takes places : First, nearly all slaughter-houses are the abundant resort of rats, which feed upon the refuse material, and thus after'a time often become trichi- nous. During the first period of intestinal irritation in these animals some of the adult worms may be discharged with the evacu- ations, and accidentally mingled with the food of the remaining pigs. It is possible, also, that pigs may occasionally seize and devour rats dead or dying from trichinosis. Secondly, the waste bits of flesh and the general debris of slaughter-houses are some- times, when removed by washing, allowed to run into the feeding-troughs ; and lastly, the flesh of a pig dead from incidental causes, and therefore not considered as fit for the market, may be used as food for the re- mainder of the drove. In some or all of these ways a certain number of swine may be annually contaminated, and thus serve to perpetuate the disease. The methods, accordingly, which are most likely to reduce its frequency, and, if possible, to extermi- nate it altogether, are—first, the maintenance in slaughter-houses of extreme cleanliness, no waste material being permitted to re- main over night to serve as an attraction for rats, nor allowed to mingle with the food of the remaining pigs; and secondly, swine should never be fed with the flesh of one of their own species which has died from in- jury or disease. Trichinia'sis, or Trichinosis, a disease induced by eating the trichinous flesh of swine. (See Trichina spiralis.) Tu/bercle [Lat. tuberculum], a name ap- plied to certain diseased and degenerative products in the animal body, and chiefly interesting in its relation to pulmonary phthisis or consumption. In the remote periods of medicine persons dying of con- sumption were known to have in their lungs yellow masses of cheesy consistency. These were rudely designated tubercle. By Stark in 1785, by Matthew Baillie in 1794, and Boyle in 1810, a new body was described, termed miliary tubercle; this minute body, about the size of a millet-seed, of gray color, semi-translucent, and of gelatinous consistency, has come to be regarded as true tubercle. The miliary or true tubercle is therefore to be looked for in the acute tu- berculosis of children, in tubercular inflam- mation of the brain, pleura, peritoneum, and wherever in a consumptive and tainted constitution acute marasmus supervenes. The yellow masses, now known as crude tubercle, have been resolved by the micro- scope into wasted, shrivelled cells and fatty granules, which give the homogeneous cheesy consistency. Hence, so-called " yellow tu- bercle" may be the second and advanced stage of true tubercle, or the " fatty degen- erative," retrograde stage of innocuous 'ma- terial in the body, as when acute inflamma- tion has given rise to plastic lymph, which fails to organize. Under such circumstances, in a person hitherto healthy, with no tuber- cular tendency, an unfortunate inflamma- tory attack may lead to deposits which be- come fatty or " cheesy," and these caseous masses liquefy or soften, forming cavities. THE FAMILY PHYSICIAN. 117 It is, then, the tendency of abnormal de- posits, whether true tubercle or simple cheesy matter, to compress the healthy tissues and cause their waste, and to soften and form cavities, that leads to consumption and death. Yellow tubercle is most liable to develop, following acute sickness, in those who are delicate and ill-nourished. The relation of miliary or true tubercle to the scrofulous or strumous diathesis is unsettled, the opinion steadily gaining that " scrofula is the soil in which tubercle grows." Buhl, Sehuppel, and others claim that tubercle develops upon the minute lymphatics which permeate all the structures of the body. (See Consumption and Scrofula.) Tubercular Meningitis. See Meningitis. Tu/mor [Lat., a "swelling"], in patholo- gy, is defined by Boyer as "any preter- natural eminence on any part of the body," but in a narrower sense swellings which are the recognized results of inflammation and extravasation are excluded, Tumors are primarily divided into two great classes, malignant and non-malignant tumors. To the first belong all the numerous varieties of cancer, epithelioma, and the various can- croid diseases. (See Cancer.) To the second class (benign tumors) belong a vast number of varieties, the classification of which is difficult. A convenient mode is that which classes them according to the tissue of which they are composed. They may be arranged as follows: (1) Fibrous, fibroid, and connective tissue tumor, fibro- ma ; (2) fatty tumor, lipoma; (3) cartilage tumor, chondroma; (4) bone tumor, osteoma, exostosis; (5) muscle tumor, myoma; (6) nerve tumor, neuroma ; (7) erectile, cavern- ous, or blood tumor, angioma; (8.) the so- called sarcoma, or flesh tumor, which, according to Billroth, consists of develop- mental connective tissue which does not become perfect bone-cartilage or other tis- sue, but undergoes some one or more of several peculiar degenerative changes; many varieties are noted: (9) lymphoma, or hypertrophy of the lymphatic and other ductless glands; (10) papilloma, or hyper- trophy of skin elements; (11) cystoma, hollow or cystic tumor, containing a fluid or semi-fluid mass. It may be observed that many tumors combine the characters of two or more of the above classes, and also that, according to a prevalent doctrine, many apparently benign tumors approximate and may finally take on malignant characters. typhoid Fe'ver. See Typhus and Ty- phoid Fevers. Ty'phus and Ty'phoid Fevers [lyphusfaom Gr. rv(pog, "stupor;" typhoid, from Gr. rvyog, "stupor," and eldog, "form"], two idiopathic or essential continued fevers, by some au- thorities regarded as a greater and lesser degree of one common disease, but by a majority of physicians conceded to be dis tinct diseases with certain resemblances. Typhus is the more acute, virulent, and fatal, the more sudden and pronounced in its onset, rapid in its course, and in cases of recovery terminating promptly by a crisis. Typhoid is insidious in its development, less abrupt in its onset, slower in the develop- ment of its symptoms, which are less acute, and terminates by a prolonged and gradual convalescence. Typhus is known as ship- fever, jail-fever, camp-fever, etc., being the product of vast aggregations of humanity under unhygienic conditions, especially de- ficient ventilation; so that the rebreathing of air loaded with emanations from crowded living beings is its chief cause. With the sanitary reform of barracks, ships, prisons, etc. it has been reduced to a minimum. Typhoid fever is far more prevalent, occur- ring in all countries, among all classes of society, in isolated and healthy country vil- lages as well as in the larger towns and cities. It has variable degrees of severity, and a variable predominance of different classes of symptoms in different persons and seasons. It may be induced by purely ex- ternal causes, as by bad ventilation, sewer- gas, exhalations of decomposing matter in cellars or near houses, privies, and especially the contamination of drinking water, as when springs or wells receive by percolation the surface-water from outbuildings. In other cases typhoid fever would seem to have a purely intrinsic origin, the morbific matter being collected within the person's system by deficient elimination. Thus, it is induced in persons of nervous temperament by prolonged and excessive mental or bodily effort, care, exposure, fatigue, and privation of food. The nervous type is then developed, justifying the German designation of "nerv- ous fever," since the depressed nervous sys- tem suspends the nutritive processes of the body, and effete matter becomes present in excess of the nutritive supply. Typhoid fever is also known as adynamic and asthenic fever, indicating the peculiar exhaustion characterizing it; pythogenic fever (Gr. ■Kvdog, "filth," and ysvao), to "generate"). In typhoid fever the Peyer's glands of the small intestine are invariably swollen, infil- trated with typhoid matter, and often ulcer- ated or sloughed out; hence from this specific lesion the disease is also called enteric fever, abdominal typhus, and ileo- typhus. Typhus fever has an average dura- tion of two weeks, characterized by initial chill, active delirium, contracted pupil, dark- coated tongue, dusky suffusion of the face, a i high temperature, a rapid and feeble pulse, 118 THE FAMILY PHYSICIAN. and often weak heart-sounds. The body- heat rises steadily, remains constant at its height, when at the end of the second week speedy recovery ensues, with profuse per- spiration, or the case becomes more serious or fatal. Exceptionally, the relapse is ter- minated by a crisis as late as the end of the third week. Typhoid is of longer duration —at least three full weeks of the active fever, and several weeks of gradual conva- lescence. During a week to ten days ante- cedent to the actual attack the specific poison or materies morbi is incubating, and the pa- tient is languid, feeble, and depressed. It is ushered in by headache, chill or chilli- ness, and elevated temperature; later, follow muttering delirium, semi-consciousness or "coma-vigil," wild excitement and tossing of the body, picking of the bedclothes ; the face is suffused and blank, the tongue coated; the teeth may have "sordes," a de- posit of blackened and dry saliva; the abdomen is tender on pressure, tumefied, and emits a drum-like sound when per- cussed ; the bowels are often loose, the stools being " ochre-colored," and often found to contain the shreds or entire body of slough- ing intestinal glands ; in the second week in many cases minute spots appear on the lower part of the chest and upper part of the abdomen, coming in crops of twelve or more, each crop lasting about three days. The temperature, as shown by the medical thermometer, has a peculiar and almost diagnostic course in typhoid fever. There is after the initial rise an ascent for four or five days of about 2° F. each evening, and a descent in the morning of 1° F., making a dailv gain of 1° F. Thus, the temperature reaches 103°, 104°, 105° F.; it then remains nearly constant for several days, when to- ward the end of the second week it has a gradual descent in the same manner of a degree daily ; during convalescence there is a marked daily variation of temperature, resembling intermittent fever—an evidence of the debilitated and susceptible state of the convalescent, and of the periodic efforts of the recuperating system to cast off mor- bific matter. The modern treatment of typhus and typhoid may be summed up chiefly as good nursing, fresh air, food, and support by tonics and stimulants. Cold water may be of the greatest value, either sponging, the cold pack, affusion, or immer- sion, to reduce the unusually high and dan- gerous temperature of the body. (See arti- cle Fever.) UFcer and Ulceration [Gr. eAmg; Lat. ul- cus], the process of molecular death or dis- integration occurring on the surfaces of the body at points where nutrition is low in eonsequence of local irritation or injury or defective circulation and bad states of the blood. Localized inflammation is often the determining cause of an ulcer, by locally oc- cluding the capillaries and arresting or weak- ening local circulation and nutrition ; thus, the canker is often an ulcer in the mouth due to stomatitis ; the ulcerated tonsil has been previously inflamed, either acute or chronic. Sluggish venous circulation often causes ul- cers, as ulcers upon the legs from varicose veins or weak circulation of the aged ; ulcers upon haemorrhoids or varicosity of the anus. When wounds have failed to heal promptly, their border and surface may take on the ulcerative process, and become bathed with a weak watery serum containing black gran- ular detritus. The presence of foreign sub- stances, as a splinter in the flesh or dead bone in a limb, creates secondary ulcers. Pressure and constant irritation are causes, as upon the feet from ill-fitting boots, and bed-sores from long lying. Lowered nerve- tone and depressed temperature favor ulcer- ation, the paralyzed limb easily ulcerating. Ulcers are classed as—(1) Simple or healthy ulcers, if the term is not a misnomer—that is, ulcers having a healthful tendency to heal. (2) Weak ulcers, lacking the florid color and healing tendency of the first class; they often result from the debilitated health of the sub- ject. (3) Indolent ulcers; often all recupera- tive power is lost; usually the border is thick- ened and elevated, and may be indurated. (4) Irritable ulcers are painful, and may bleed upon touch. (5) Inflamed ulcers. Ulcers are liable to become inflamed upon slight local irritation or derangement of the blood, use of alcohol, and exposure to cold. (6) Sloughing ulcers, conditions often following the inflamed ulcer or very low states of health. (7) Serpiginous ulcers, when some specific vice of the blood gives it a tendency to spread, and it pursues a tortuous, serpen- tine course. (8) Specific ulcers, with under- mined edges, due to primary deposits be- neath the skin, which soften and discharge upon the surface. The simple ulcer needs simply to be kept clean and protected by any bland cooling lotion or ointment; the weak and indolent requires stimulating applications; the indu- rated often requires the incision of its thick- ened borders or removal by strapping with plaster; the elastic bandage will effect a speedy cure in many cases; the inflamed ulcer calls for cold and evaporating lotions—the slough- ing for antiseptics. In all forms the diet must be rich, the appetite maintained by tonics, and the blood enriched by iron and often alteratives. UmbiFical Hernia. See Hernia. IFrinary CaFculi and Deposits. Deposits. —Urine in disease often deposits on stand- THE FAMILY PHYSICIAN. 119 ing various kinds of sediments, which differ in properties and composition according to the causes which induce their formation. Both morphological and chemical bodies are thus separated. The former class in- cludes such substances as blood, pus, and mucus-corpuscles, epithelial scales, sperma- tozoa, etc.; to the latter class belong urates, uric acid, phosphates, calcic oxalates and carbonates, hippuric acid, cystine, leucine, xanthine, tyrosine, etc. These deposits form light flocculent powders or compact grains (gravel), or they collect in larger con- cretions, forming calculi. The most com- mon sediments contain uric acid. This often separates in a free state, forming red gravel, or it is deposited in the form of am- nionic or sodie urates, which sometimes ap- pear in perfectly healthy urine. A crystal- line or amorphous deposit, consisting of ammonio-magnesic phosphate, forms what is known as white gravel. Calculi in the Bladder.—These vary greatly in size and composition, and are frequently composed of concentric layers of different composition, arranged around a clot of blood or a foreign substance as a nucleus : the exterior layer is often phosphatic, but never uric, in character. The most typical forms have the following composition: Uric. .... 92.8 .... 3.2 1.0 .... 3.0 Phosphatic. ... 9.77 Ammonio-magnesic phosphate.... , 34.74 38.35 3.14 2.55 .. 6.87 Oxalic. .... 63.5 , 6.2 .... 30.3 As a rule, the oxalic calculi are the hardest, the phosphatic being the softest. The fol- lowing are the best characterized forms of calculi: Uric add calculi, of a brownish-red color and smooth surface. When heated they fuse, and emit a peculiar odor, leaving but a little ash. They give the reactions for uric acid. Ammonic urate calculus is rare in occurrence. It is more easily soluble in water than the preceding, and dissolves in hot po- tassa solution, witb evolution of ammonia. Caldc oxalate constitutes the mulberry calcu- lus, which has a dark-brown color and is very hard. When heated before the blow-pipe. it first blackens, then burns to a white ash consisting of calcic carbonate. It dissolves in hydrochloric and in nitric acids, but not in acetic acid. Calcic phosphate forms the bone earth calculus (08P2Ca3), which is of rare occurrence, and often consists of lam- inae of crystals radiating from a nucleus. It is of a light-brown color, dissolves in hydrochloric acid, but is infusible before the blow-pipe. Ammonia - magnesic phosphate, or triple phosphate calculus (08PAIg_,Am2), is white and brittle; fuses with difficulty, emitting an ammoniacal odor, and readily dissolves in acids. Fusible calculus, which ap- pears to be a mixture of the two preceding varieties, forms white friable masses which often acquire a large size. It fuses readily, and is easily soluble in acids. Xanthine calculi are of a pale-brown color, have a lamellar fracture and a polished surface, which acquires a high lustre when rubbed. They dissolve in potash solution and in nitric acid, but very sparingly in hydro- chloric acid. Cystine calculi are semi-trans- parent, and have a dark-yellow color and a crystalline texture. The last two forms are of unfrequent occurrence. Compound cal- culi, consisting of a succession of laminae composed of several of the foregoing vari- eties, also occur. (See article Calculus or Stone.) IFrine, Retention of. See Eetention of Urine. IFterine Diseases. Diseases of the womb or uterus, so-called " female diseases," are comparatively infrequent in the women of aboriginal and savage tribes, and in civ- ilized races among the women of rural dis- tricts who labor, are much in the open air, and free from artificial and effeminate habits of dress and living. For the most part they exist in delicate women, those whose health is impaired by some other and primary dis- ease, and relatively more often in women resident in great cities. The predisposing causes of a majority of all uterine diseases are the constant recurrence during the great- er part of adult life of the menstrual period, the complications and sequelae of child-bear- ing, and the intimate nervous and vascular sympathy connecting the uterus with every part of a Avoman's organism. Uterine dis- eases comprise also the derangements of the appendages of the uterus—the ovaries, va- gina, and peri-uterine connective tissue and ligaments which maintain the organ nor- mally in situ. The uterus is subject to con- gestion and to inflammation from many causes, as suppressed menstruation, catching cold, falls, blows upon the abdomen. Con- gestion and inflammation are indicated by a sense of fulness, weight, warmth, and pain, with tenderness on pressure in the lower part of the abdomen, especially in standing or walking; and relieved by lying down. The disease may be limited to the inner 120 THE FAMILY PHYSICIAN. mucous membrane, to the body of the organ, or the exterior investing loose tissue, or rare- ly involve all. The term metritis denotes inflammation of the body proper of the organ, endo-metritis of the mucous interior, peri-metritis of the surrounding elastic tis- sues which fill the cavity of the pelvis. This tissue, when extensively inflamed, is often infiltrated with new plastic matter, the prod- uct of the vascular engorgement, and this, becoming set, " fixes " the uterus for a time, so that it is rigid and immovable—a con- dition termed pelvic cellulitis and peri-uter- ine cellulitis. This loose tissue is occasion- ally the seat of profuse haemorrhage from a ruptured vessel, as in lifting, jumping, or falling. The effused blood remains fluid or semi-fluid, and gravitates in the pelvis; this blood-tumor, termed " pelvic haematocele," often presents in the vagina. The normal uterus is a symmetrical organ, with a straight axis, and the cavity of its body and neck slightly open; its normal position is that of slight anteversion, or upright, and from above inclining slightly backward. But attacks of congestion and inflammation change its shape, size, sym- metry, and position. Thus, either from ex- ternal pressure or adhesions, or from soften- ing or thickening of its own walls, it may be drawn down—either backward, forward, or to either side; the organ as a whole may be tilted, giving rise to " version;" or the body may be bent on the neck, a condition termed " flexion." According to the direc- tion which the displacement or deformity of the uterus takes, we have anteversion, re- troversion, right and left lateral version, and anteflexion, retroflexion, and right and left lateral flexion. Flexions of the uterus are a common cause of " dysmenorrhoea," or difficult menstruation, since by the bending of the uterus its canal is bent and constrict- ed, and the free escape of menstrual blood is prevented; this flexion of the uterine canal is also a cause of sterility, since sem- inal elements cannot enter the organ and produce conception. Whenever the uterus is enlarged, as by congestion or inflamma- tion, is the seat of a polypus or tumor, or is pressed down by growths in the cavity of the abdomen, and also whenever in debili- tated persons its ligaments and outside sup- ports are weakened and relaxed, it tends to gravitate below its natural position in the pelvis, and even to project from the body. This "falling of the womb" is termed "pro- lapse," and, when extreme, "procidentia." The lower end of the uterus, the neck or cervix, is often ulcerated as the result of congestion, inflammation, contact of its end with the floor of the pelvis, and the irrita- tion of the acrid mucus discharged in endo- metritis. Tumors may develop within the cavity of the uterus, in the substance of its walls, or upon its outer surface, either be- neath its serous covering or loosely attached by pedicles. The uterus is occasionally the seat of cancer, and chiefly at the climacteric period or " change of life." The ovaries— whose functional work, the production and periodic discharge of the ovules, is the para- mount physical feature of woman's sex—are subject to attacks of congestion, inflamma- tion, haemorrhage, and intense neuralgia. The fibrous framework of these organs may increase and develop fibrous tumors; but especially frequent and important are " ova- rian cysts " or " ovarian dropsy." The ovisac becomes distended with fluid in order to rupture and eject the ovule; it then, again, is filled by the serum of the coagulated blood from the haemorrhage consequent upon the rupture. The ovisac is liable to fill, and by a process of vascular activity and growth in its wall becomes a cyst of greater or less size: cysts may be present of small size and in numbers never attracting attention, or, reversely, grow either by secretion or drop- sical transudation to contain ten, twenty, sixty, or more pounds of serous fluid. Such ovarian cysts may be single sacs, or divided by partitions into compartments. The broad ligaments on either side of the uterus less often are the seat of dropsical cysts devel- oped between their folds. The vagina, the intervening passage which connects the sur- face of the body with the womb within, is the frequent seat of catarrhal inflammations, in which mucus is more or less profusely secreted, causing a discharge termed " leu- corrhoea" (Gr. Aevnog, "white" (matter), and pElv, to " flow "). It may also be acutely in- flamed, " vaginitis;" the seat of ulcers, and also of spasm, witb or without pain, a con- dition termed " vaginismus." This passage is, very exceptionally, anatomically defec- tive, being wholly or partially wanting or constricted. Most common of all uterine diseases are merely functional derangements or irregularities of menstruation. By amen- orrhoea is understood absence of menstru- ation ; dysmenorrhoea is characterized by pain, sickness, and deficient flow at the period; and menorrhagia is a prolonged and excessive menstrual flow, or persistent loss of blood from the uterus, as when can- cer or polypus exists. In the treatment and cure of uterine diseases correct diagnosis is essential at the outset. True, most of them are benefited by use of general tonics, by rest, corrected habits, and by supporting the abdominal viscera; but many are not even alleviated by these general measures. Physi- cal exploration, both manual and by aid of the speculum, will often reveal an unsuspect- THE FAMILY PHYSICIAN. 121 ed disease, and point to the special topical treatment or surgical procedure which is the essential means of cure. Vaccination [Lat. vacca, a "cow"], the in- oculation of the human being with vaccine or cowpox, to protect against smallpox or variola. Jenner discovered vaccination in 1796. He had previously observed that milkmaids who contracted the pustules of cowpox in their hands while milking cows affected with vaccinia did not have small- pox. He further demonstrated that vaccine virus, when "humanized"—i. e. transmitted from arm to arm through many persons— preserves its protective efficacy against small- pox. Vaccination has replaced inoculation (with virus of smallpox), and is now gener- ally practised in all civilized countries. In many it is obligatory; in England every in- fant must be vaccinated before three years old. Vaccination has had the result (1) to reduce the prevalence of smallpox to a mini- mum. In centuries past a majority of per- sons had it, and 30,000 persons have died in one year of it in Great Britain; now but a few hundred. (2) To diminish the danger of individual attacks, as the type of the dis- ease has been rendered mild by hereditary influence of vaccination. Exceptionally, the disease attacks the vaccinated, but in a mild form, varioloid. There is no danger of transmitting disease by vaccination (1st) if only cowpox, which has never entered the human body, be used; (2d) if in using human- ized virus—i. e. taken from a child's arm or the scat)—healthy children only are used as agents of transfer; and even in doubtful eases if only vaccine lymph, free from blood, is taken. Vaccination is usually performed on the arm, at the insertion of the deltoid muscle. The Spanish vaccinate girls on the leg, to avoid the scar on the arm. Vaccina- tion should be carefully performed with a clean lancet or needle. The vaccination matures on the eighth day—a circle of white vesicles with a red congested base or areola. Jenner said it looked like pearls on a rose- leaf. After the eighth day there may be much swelling and soreness, and a scab forms, to drop off on the twenty-fourth day. Vac- cination had better be done by a physician, and never near the joints, as serious results follow from inflammation. Vaccination should be repeated once in seven years until mid-life. Physicians, nurses, and other ex- posed persons should be vaccinated more often. When a person has been directly exposed an immediate vaccination antici- pates smallpox, as that disease has twelve to fourteen days for incubation. Varicose Veins, relaxation of the coats of the superficial veins, with increased cali- bre, occurring most frequently in the lower extremities. Gravitation, the weight of the venous blood-column above, and the difficulty of the ascent of blood from the feet to the body, determine the greater frequency of the disease in the veins of the legs. Varicose veins are common in aged men, the result of senile degeneration of the various tissues, including attenuation of the coats of vessels; less often it occurs in mid-life to robust men of the gouty habit, and who by vocation are constantly standing; walking does not favor the condition, since the movements of the superficial muscles and tension of the in- tegument help to lift the blood upward. Even in youth violent exercise, as in the gymnasium, by unduly taxing the tension of the vascular system, causes a breaking down of the valves in the veins and venous dilatation or varicosity. In women the chief and not unfrequent cause is pregnancy. Wo- men who have borne several children will often have marked varicose veins, the result of the pressure of the gravid uterus upon the veins in the pelvic cavity, and conse- quent detention of the venous blood in the lower extremities. Varicose veins occur ex- ceptionally in other parts of the body—upon the scalp and side of the neck, and upon the abdomen in the region of the groin. Vari- cocele in the male is a local varicosity of the spermatic veins. Haemorrhoids or piles are due to repeated passive congestions of the haemorrhoidal veins at the verge of the anus; obstruction to the portal circulation is the primary cause, but if of frequent recurrence and long standing the veins become varicose. Varicose veins, as seen in the lower extremi- ties, are increased in diameter with inequali- ties of calibre, and present nodular enlarge- ments or pouches at intervals; there are greater relaxations at the site of former valves or at the points of division of veins. The veins are also tortuous, since the longitudinal fibres of the coat are relaxed no less than the circular; the tortuosity accommodates the increased length of the vessel and favors the ascent of the blood. Varicose veins when appearing do not necessarily indicate debility or degeneration, but should warn the patient at once to abandon vocations in- volving violent exertion, to habitually regu- late the diet and bowels, and neutralize and remove any rheumatic or gouty vice. The varicose limb may be benefited by daily friction, cold effusion, and salt bathing. But the extension of the disease is best checked, and the best prospect of cure ensured, by constant external support. This is secured by uniform bandaging, or by wearing an elastic stocking or laced leg-corset. The elastic stocking, made of rubber webbing, is of the greatest value to those who can afford the silk and rubber webbing and 122 THE FAMU/ keep them constantly renewed when stretched by wear. The inferior stocking by stretching at points leaves bands of circular constric- tion which aggravate the disease rather than give the intended benefit. The cheapest and most efficient appliance is a case or corset of strong jean fitted to the shape of the limb and lacing up in front. Varicose veins are radically cured by ligation and by hypoder- mic injection of a drop of liquor ferri-per- nitratis within the vein. The latter method, carefully performed, may afford permanent relief, with the precaution to tightly band- age the part for several hours to prevent blood-clots from reaching the heart. Arsen- ical preparations act well on varicose veins. Varioloid. See Smallpox and Vacci- nation. Vene/real Diseases. See Blenorrhcea, Chancre, Gleet, Gonorrhoea, Stric- ture, Syphilis. Ven'om [Lat. venenum], the poisons elabo- rated by healthy animals as distinguished from virus, the virulent liquid product of disease in animals or man. Some insect stings are virulent, though as a rule they are mild and relieved by simple measures. Bees and wasps as a rule leave their sting- in the wound they inflict; this should be extracted, the wound protected from the air or bathed in cooling and stimulating evapo- rating lotions; ammonia is a useful applica- tion. The scorpion is dangerously venom- ous in the tropical regions of the Indies and Africa, but in the milder climates it inhabits does little harm. Contrary to the fabulous accounts of the tarantula venom, it rarely causes death, and seldom causes alarming symptoms. In all countries there are ven- omous serpents, their number diminishing with increase of population and high culti- vation of soil. Islands are comparatively free. Ireland is said to be quite free, and England has but one, the viper. The chief venomous serpents of the U. S. are the rat- tlesnake, moccasin, and adder. The phoora of India and the cobra are exceedingly vir- ulent. The venom of serpents is elaborated in special glandular apparatus adjacent to the mouth, stored in a sac or canal, and reserved for sudden voluntary ejection as a part of the reptile's means of self-defence. The effect of the poison upon man may be immediate, rapid, and speedily fatal, or slow and incomplete. The venom, which prob- ably has definite living germs, a contagium vivum, is believed to rapidly multiply itself in the blood, and quickly pervades the en- tire body, vitiating the red corpuscles and the nutrition of the tissues. In some cases the nerve-centres are primarily attacked, various nervous phenomena being speedily followed by paralysis of the medulla ob- PHYSICTAN. I longata, and death. More often a definite period, short or long, intervenes before death. A prickling, burning pain is felt in the wound, increases to intensity, and extends to adja- cent parts. The limb or part swells and in- flames (phlebitis), and as a result of ob- structed circulation the part becomes speed- ily a'dematous or dropsical, and assumes a variety of changed colors from disturbed circulation and the decomposed state of the blood—from dark red to livid white, to blue, purple, mottled, and leaden hue. The limb may become cold, and, if life is not destroy- ed, in time slough away. These changes may extend over the entire body. The mind is anxious, depressed, often deranged. Breath- ing is embarrassed, there is profuse sweating, vomiting, and jaundice, and death occurs by paralysis of the nerve-centres or exhaustion. Venomous wounds should at once be I cleansed, encouraged to bleed freely by suc- tion or excision, a ligature speedily placed on the limb, or the part sedulously rubbed toward the wound and away from the centre of circulation, to evacuate all contaminated blood. Bold and thorough cauterization is of value. Strength is to be kept up by the heroic use of alcohol, ammonia, and other stimulants. (See Poison of Serpents.) | Ver'mifuges [Lat. vermis, "worm," and fugare, to "cause to flee"], also termed Anthelmintics [Gr. avri, "against," and I eAyivg, " worm "], also Helminthagogues [Gr. EAuivg, " worm," and ayuv, to " lead" or "expel"], remedies intended to remove ! worms from the stomach and intestines, and prevent their recurrence by the destruction of their germs. Properly they are fco be distinguished as vermicides, or those which kill the worms, and vermifuges, those rem- edies which by moving the bowels violently j or by their rough or irritating qualities dis- i lodge and bring away the entozoa alive. | The remedy that is destructive to the worm | must at the same time be innocuous as re- gards the patient, and not injurious to the alimentary tract. Remedies which simply stupefy or destroy the worm must be follow- ed by the exhibition of an efficient purga- tive to remove the destroyed parasite, as well as to demonstrate the success of their action. Pink-root (Spigelia marilandica) is well known, and for children much used in I the form of fluid extract of spigelia and | senna. The oil of wormseed (Chenopodium anthelminticum) is employed, as is Spigelia, I against round worms. For the same pur- | pose, and preferable, is santonine, the acid extract of Santonica or Levant wormseed i (Artemisia contra). It is pleasantly admin- i istered in flavored lozenges; may be given at night, followed by cathartics in the morn- | ing. Cowhage (Mucuna pruriens) is less THE FAMILY PHYSICIAN. 123 used than formerly. Thread-worms are usu- ally in the lower bowel, and easily removed by enemata of salt and water, aloes in milk, or any irritating or astringent material in solution. The removal of tapeworm is often difficult. Remedies should, as a rule, be preceded by free evacuation of the stom- ach and bowels by cathartics, and little food taken at the time. The best opportunity is thus given to dislodge the head, which ad- heres by tentacles or hooklets; for, though many yards of the worm be evacuated, ex- cept the head be obtained there is no cure. The chief remedies for tapeworm are pump- kin-seeds broken up and given in an electu- ary of sugar or emulsion of water or milk, followed by a purge; turpentine in emulsion of acacia mucilage and castor oil; decoction of pomegranate; the oil of male fern (Filix mas); and, preferably, kousso (the flowers and fruit of Braycra anthelmintica, a tree of Abyssinia). It is efficient, yet safe to the patient, and gives little inconvenience. Each morning half an ounce of the powdered flow- ers is taken in water, or 20 to 40 grains of the active extract, kousine, may be taken in a wafer. No purge is necessary; watery stools are produced, and the worm is dis- charged dead. (See Anthelmintics.) Ver/tigo [Lat.], a subjective or apparent impairment of the equilibrium of the body. It assumes two principal forms: In one it ap- pears to the subject as if the objects in his vicinity were whirling about him; in the other, he fancies that he is forced to fall in some definite direction, forward, backward, or to either side. Vertigo is rarely if ever con- tinuous, bjut occurs in paroxysms provoked by some appreciable cause, as changing pos- ture, eating, using the eyes, etc. The sub- jects of vertigo often stagger or fall in con- sequence of the sensation of motion. Ver- tigo is sometimes the expression of disease of the brain, or of interference with the circulation of blood in that organ, but more usually it is a sympathetic disorder, caused by indigestion, anaemia, sudden impairment of parallelism between the two eyes, disease of the internal organs of hearing, etc. Ver- tigo may be artificially produced by the ad- ministration of stimulants (alcohol), and by the application of galvanism to the head in a transverse direction or to the superior ganglion of the cervical sympathetic nerve. A variety of subjective unsteadiness, with- out definite direction to the apparent move- ment, is better designated as dizziness. Temporary relief is given by alcoholic stimulants, ammonia, musk. The proper management of vertigo consists in the treatment of the disease causing it. VPrus [Lat.], animal fluids produced in diseased conditions or by morbid processes, and capable of developing disease when transmitted to other animal bodies. Thus, man may be inoculated by the virus of hu- man origin, smallpox, syphilis, etc., vac- cinia of the cow, glanders of the horse, and rabies canina or hydrophobia. A minute amount of the virus gaining access to the body is sufficient, by self-multiplication, to infect the entire volume of the blood and contaminate every part of the body. Pecu- liar cells or germs, having temporary vital- ity and tendency to reproduce themselves (contagium. virum), constitute the active ele- ments of all viruses. Having gained entrance to the system, they for a time seem dormant, but are really multiplying, and this period is well designated as one of "incubation." Thus, smallpox appears twelve or more days after admission of virus, vaccinia within a week, hydrophobia on an average forty days. There are no specifics against the effects of viruses when once in the system. Hygienic and supporting measures may prepare the body to meet those effects and pass safely through. (See also Venom.) Vision, Defects' of. See Sight, Defects of. Voice, Loss of. See Aphonia and Throat, Diseases of. VonFiting [Lat. vomo, -Hum, to "throw up;" see Indigestion]. Vomiting is a reflex contraction of the muscular coats of the stomach, ejecting its contents. It is an involuntary and spasmodic act. Vom- iting may be the result of disease of the brain, of the pneumogastric nerve, of the walls of the stomach, of catarrh or inflammation of its mucous lining; it may be the result of indigestible food, bile or mucus in the cavity of the sto- mach, or a sympathetic reflex result of disease in other organs, as the uterus, ova- ries, or liver. The vomiting of pregnancy and of uterine or ovarian disease, the pecu- liar morning nausea and vomiting of Bright's disease of the kidneys, bilious vomiting, vomiting of gastric catarrh, and the vom- iting at the onset of acute fevers and erup- tive diseases of children, and vomiting from surgical causes, as fracture at the base of the skull, concussion and inflammation of the brain, are to be distinguished, each from the other, in some instances by peculiar features of the act of vomiting, but more often by observation of the associated symp- toms. (See Stomach, Diseases of.) At the onset of vomiting the face may be deathly pale; the surface becomes cool and bathed with clammy sweat; the pulse small and feeble; and great prostration re- sults. In some instances faintness occurs, or even fatal syncope. An occasional acci- dent during vomiting is the impaction of 124 THE FA MIL solid food or artificial teeth in the larynx, causing suffocation. Robust persons, but little depressed by vomiting, become red in the face during the effort, and later are cool and slightly pale. The clothes should be loose when vomiting, fresh air in the room, water at hand for cold affusion to the face if needed. Stimulants may be needed to counteract collapse. Ice, carbonic-acid water, creosote, oxalate of cerium, dilute hydrocyanic acid, are useful remedies. VonFiting of Blood. See HyEMATEME- SIS. Warts, or VerriFc* [Lat. verruca, a "wart"], are developed by hypertrophy, abnormal growth, of the papillae of the skin. They may be round and ovoid or conical, thread-like, or broad and flat. The so-called "seeds" or points of a dry wart correspond to the number of papillae which have become elongated and thickened. Each papilla of the skin has an independ- ent supply of blood by a little loop of capil- lary blood-vessels at its base. Hence, mere removal of the wart is followed by its renewal from the well-nourished base and remaining cells which have transmitted the tendency to excessive growth. Cases are often cited of warts communicated by the blood from other warts, but the best author- ities deny them. Warts occur chiefly in children, between the second and fourteenth year; their cause is uncertain. Their dura- tion is indefinite ; they sometimes disappear suddenly, probably by contraction of the vas- cular papillary base and casting off of the su- perabundant dry cells. When they are kept free from handling or irritation, the diet is corrected, and alteratives are given, they may slowly disappear. The common treat- ment is to snip them off and touch the base with nitric acid, glacial acetic acid, or lunar caustic; saturation with tincture of thujar or thuya (arbor vitse) daily has the effect to speedily remove them in many cases. Wa'terbrash. See Pyrosis and Indi- gestion. Water on the Brain. See Hydroceph- alus. Wax'y Degeneration, a diseased condition of the tissues of the living body, in which parts of organs are changed into the sub- stance known as lardaceine, or "animal amyloid," a peculiar albuminoid substance which some have tried to identify with the glycogene of the liver. Though an albumi- noid, it has reactions somewhat like those of starch. It takes a deep-brown red from iodine, dissolves in warm water, cannot be melted, swells but does not dissolve in sul- phuric acid, and does not dissolve in ether. It is apparently isomeric with albumen (Friedrich and Kekule). It has often been PHYSICIAN. confounded with true starch, with which it is sometimes associated. Organs seriously affected by waxy degeneration, when cut, have a half-transparent look. It has been detected in the brain, nerves, spleen, liver, kidneys, muscles, arteries, bones, glands, adventitious tissues, cancers, and in various other situations. Rickets, syphilis, pulmo- nary consumption, diabetes, chronic kidney disease, and malarial and mercurial poison- ing are among the conditions with which it is associated. It is seldom or never detect- ed during life. The treatment naturally is for the disease with which it is associated. Some cases of obscure and undiagnosticated ill-health doubtless arise from this degener- ation. Not much that is definite can as yet be said of the causes and treatment. In suspected cases the patient is to be put into the best hygienic conditions, and untoward symptoms should receive attention. Wen [Ang.-Sax. wenn], a cystic tumor oc- curring upon the surface of the body, espe- cially frequent on the scalp. It originates by the occlusion of a follicle of the skin or scalp, and the subsequent slow accumulation of sebaceous matter secreted by the lining of the steadily-increasing cyst. The tumor, therefore, is round and symmetrical, and, causing a distension of the overlying skin or scalp, is smooth and shiny. It may be j soft, semi-solid, or indurated, according as its contained sebaceous matter is fluid, rich in pultaceous fatty granules, or has had its fluid elements absorbed, leaving only inspis- sated and calcific substance. The wen is a harmless, non-malignant tumor. Whether single or present in large numbers, its re- moval is easy and harmless. The overlying tissues are to be incised, without cutting into the wen, when with the handle of a scalpel or a small ivory paper-cutter the round, ball-like cyst may be pried or peeled out. If the cyst has been cut into and the cheesy contents evacuated, the membranous sac must be seized with forceps and gently drawn out, for if left it will refill. Once properly removed, it cannot return. (See Tumor.) Whites. See Leucorrhcea and Uterine Diseases. WhiFlow, better known as Felon, a pain- ful inflammation of the fingers and toes, more often affecting the last joint of the fingers. The felon may arise from a local bruise; more often it is the result of dis- turbed and deteriorated states of the blood. From the latter causes a number of felons may develop successively. A point of local tenderness and hardness is observed; swell- ing and induration increase, with persistent, deep-seated pain, at first dull, later more! severe, with sense of tension, and ultimately THE FAMILY PHYSICIAN. 125 lancinating and throbbing. The felon in- volves the periosteum, or fibrous sheath of the bone, and the unusual pain attending this condition is due to the dense and un- yielding structure of the part and the de- generation of the inflammatory exudation into pus. The periosteum is usually sep- arated from the bone by the burrowing pus, giving rise to the sense of tension; the bone, so deprived of its sheath and nutritive vessels, is liable to die, dead bone being a frequent sequel of felon. The constitutional disturbance is marked, the result of great suffering, the local injury, and the absorp- tion of pent-up pus into the blood. When detected early, a felon may sometimes be dissipated by an ice-pack or by a small blis- ter ; more often it will progress. Early and efficient incision of the point of induration may avert further suffering and prevent the formation of much pus. Poulticing is a slower and painful way of bringing the pus to the surface; it should be evacuated with the knife as soon as detected. Dead bone and stiff joints need never follow felon if opened early. In severe cases anodynes may be needed to secure sleep and allay pain; quinine to sustain strength; and sulphites to correct the blood in recurring felon. Whoop/ing Cough, a disease generally oc- curring but once in the life of an individual, and usually during infancy or childhood, is characterized by paroxysms of convulsive coughing, followed by a long ringing in- spiration, whence the name. It is the chin- cough of early English physicians, the per- tussis of Sydenham, and the coqueluche of French authorities, and was formerly con- founded with the catarrhal affections, which it much resembles in its symptoms and earlier diagnosis. It consists of two ele- ments—a general bronchial catarrh and a peculiar hyperaesthesia or morbid sensitive- ness of the air - passages, manifested by paroxysms of protracted coughing, termi- nated by a whoop. The simple disease is rarely if ever fatal, but when complicated with pulmonary or cerebral disease it is ex- tremely dangerous. Whooping cough de- mands care in diet, warm clothing, avoid- ance of exposure to cold and damp, sus- taining remedies when the strength flags, and the use of antispasmodic and sedative remedies to allay the paroxysms of cough- ing. Chloral and bromides are efficient. Quinine in small doses may be given throughout the attack. WonFen, Diseases of. See Uterine Diseases. Worms. See articles on Anthelmintics, Ascaris, Tapeworm, Vermifuges. Wounds. Wounds are classified accord- ing to the nature of the injury, as (1) punc- tured wounds, made with pointed instru- ments ; (2) incised wounds, produced by cutting instruments or sharp edges; (3) lacerated wounds, in which the borders of the wound are irregular, ragged, and torn, and the result of great force, dull instru- ments, or tearing; (4) poisoned wounds, in which either an animal venom or virus or some impure, poisonous, or irritating mat- ter has gained entrance to the injured tissues and contaminated the blood; (5) gunshot wounds, which as a rule are penetrating and may be lacerated, but are peculiar from other wounds, owing to the character of the missile, the shock they give to the part and to the nervous system, and the grave com- plications to which they are liable. (6) Contusions and " contused wounds" are also classed with wounds, but the contusion is not properly a wound, since there is no actual solution of continuity of the flesh, unless it be an abrasion of the skin; and a contused wound is simply a punctured, in- cised, or lacerated wound whose borders and adjacent tissue are severely contused. The tissues at the seat of a contusion are often seriously injured, many minute blood- vessels are ruptured, and the escaped blood, settling in the tissues, causes an " ecchy- mosis," a black or blue-black mottling of the part. As the blood is decomposed and slowly absorbed, this color changes to black- ish-green, greenish-yellow, dark leather- color, and lighter shades till it disappears. In other contusions there is subcutaneous laceration of tissues, or such shock to their vitality that they speedily disintegrate, and the devitalized part sloughs in a mass or be- comes the seat of ulcers. Punctured wounds are relatively the most serious class, for they are often poisoned by the entrance, if not of venom or virus, of foreign matter, as rust, dust, splinters, clothing, etc., which cause suppuration at the bottom of the deep puncture, and lead to grave inflammation, erysipelas, and contamination of the blood by retained unhealthy pus. The punctured wound is to be well washed, cleansed of all blood-clots and dirt, and if deep or in the vicinity of dense fibrous tissue, as in the hand or foot, or near joints, must be freely cut and converted into an incised wound. Incised wounds heal in several ways. They heal most promptly and simply when per- fectly smooth, clean cuts, free from clotted blood, and in the flesh of persons in perfect health. Thus, a clean cut, whose borders do not gape or separate, may, if instantly closed and sealed from the air by plaster or collodion, heal in a few hours, and ap- proximately warrant the designation "im- mediate union." More often a day or two is required; the wound, being cleansed of 126 THE FAMILY PHYSICIAN. clots or foreign matter, is exposed for a moment to the air, and closed either by ad- hesive plaster or stitches of silk or silver wire. The opposed surfaces are glazed over by a film of coagulated nutritive fluid ex- uded from the blood, and this, filling the interspace, agglutinates the walls of the wound and organizes a firm " scar" or cicatrix of fibrous tissue. This scar, if a mere line, may soon disappear by absorp- tion and the part seem again perfect. Such speedy healing is termed " union by first intention " or " primary union." When a wound has been lacerated, or a considerable area of tissue has been removed, the deficit has to be made up by a slower process of new tissue-growth; new cells develop, one by one, in superimposed strata, until the level of the surface is reached, when the skin begins to heal and shoot over the raw area. This is the process of " healing by granulation," far slower than the others, and, if the wound be large, a severe tax upon the strength and health of the patient. In lacerated wounds the more ragged points if left will be destroyed by ulceration or sloughing before the wound can begin to heal, and the delay often converts the wound into a suppurating, weak, and indolent ulcer; therefore, it is better, in cases of ulceration, to remove the irregularities and convert them into incised wounds, either straight ! or irregular, which can be brought together and heal. When an incised wound has J failed of union by " first intention," its j walls become granular; they may be ap- proximated, and soon unite, constituting the j process of " union by second intention." In the granulation the growth of tissue I may become exuberant and rise above the J surrounding healing parts on the healthy, intact surface. Such excess of granulation is popularly termed " proud flesh." It must be reduced by use of astringents or com- pression, or destroyed by caustics, and the site stimulated to a healthier action. Poi- soned wounds (see article Venom) as a rule, should be laid freely open by incision, treated by disinfectant lotions, and the gen- eral strength of the patient sustained by diet, tonics, and stimulants. Contusions often call for stimulating lotions, as turpen- tine and oil, to counteract the shock of the part, and hot cloths to maintain the tem- perature and restore the circulation when cold. The healing of a wound is facilitated by pure air, regular hours for sleep, plain but rich diet, and abstinence from alcohol. The "antiseptic method" of healing wounds consists in using Lister's spray of carbolic acid or thymol at the time of the incision, or of keeping the parts constantly disin- j fected by carbolic wash or antiseptic cotton. ! Writer's Cramp. See Scrivener's Pal- sy. Yel'low Fe/ver, so called because of the peculiar yellow tinge of the skin charac- terizing it, and for the same reason techni- cally designated typhus icterode, icterus be- , ing the classical name of "yellow jaun- dice." It is not a form of typhus fever, but resembles it in the prostration, blood- disorganization, and softening of internal organs which are features in both. Yellow fever prevails chiefly in tropical and warm climates. When occurring in temperate or cold zones it has been imported in the course of commercial travel. It is indige- nous chiefly in the West Indies, upper coasts of South America, the borders of the Gulf of Mexico, and the Southern U. S, It oc- curs in isolated, sporadic cases at all seasons in seaports, to which it has been transported in ships. Rigid quarantine of all ships coming from yellow-fever localities, and their fumigation before disembarking pas- sengers and cargo, have averted the epi- demics formerly so frequent. It is gener- ally conceded that there is a specific mor- bific element, a portable fomites or fermen- tative substance, which propagates this dis- ease. This maferies morbi, when imported and let loose, will prove innocuous unless the weather be warm or mild and the air moist. It rarely develops when the mer- cury is below 70° F., and frost or freezing weather effectually terminates its career. Insalubrious, damp, low, and filthy locali- ties are more likely to be its points of suc- cessful lodgment, as when emigrants from yellow-fever ports, on landing, go to the dense and uncleanly tenement districts of the larger cities. But in the same way it may be carried into the healthiest resi- dences. It is thus the poison is imported and carried directly to certain points which become foci of the disease, from which, un- less brought under immediate and rigid sanitary surveillance, it radiates with more or less havoc. By the intercourse of busi- ness and personal visits it may be carried from the infected localities to other points, which in turn become foci of contagion. But there is no general atmospheric con- tamination, no infection, no contagion ne- cessarily, except as the air vitiated by the breath, vomit, and stools of the patient is inspired. Yellow fever is not now regarded, as formerly, a fever of malarial origin, allied to intermittent and remittent. It prevails on the coasts and in large cities, sparing the contiguous country, which is often swampy and afflicted severely by malaria. The ne- groes of the South, although susceptible to malaria, enjoy a relative immunity from yellow fever. Yellow fever haa no perio- THE FAMILY PHYSICIAN. 127 dicity—that is, alternations of febrile periods and remissions; from the onset of the at- tack to its termination it is a continuous fever. Quinine and other antimalarial rem- edies do not control it, or especially relieve it beyond their general tonic effect. Yellow fever has no definite duration of its period of incubation or formation. In some cases, for two or three days or more, there will be general lassitude, loss of appetite, and sense of debility. In graver cases the attack may be precipitate and speedily fatal; reversely, there are "walking cases," in which, with jaundice and even mental disturbance, the muscular power is retained. There is usu- ally an initial chill, some headache, and slight increase of temperature. Exception- ally, the thermometer in the mouth or ax- illa will register a high degree, as in other fevers—103°, 104°, 105° F.—but more often the body-heat is but little elevated, and in some cases is lowered. The pulse is but little accelerated. The stomach is irritable at an early date, due to the poisonous influ- ence of bile in the blood upon the origin of the pneumogastric nerve, as well as by sym- pathy with the congested liver. The mind may be mildly or actively delirious. The skin grows yellow, and, when vomiting causes exhaustion and wasting, is often shrivelled. The blood has become seri- ously impaired by the morbific poison, and its decomposed and watery elements tend to transude the coats of the vessels. Hence, with the effects of vomiting, vessels in the congested stomach are unloaded, and the already disorganized blood, being further perverted by the action of gastric juice, presents a coffee-ground, or again a tar-like, appearance, known as "black vomit." This is regarded as a critical or even fatal sign ; and with reason, since it is an evidence of serious destruction of red blood-cells. Ex- haustion and collapse are the result of such conditions unless stimulating and sustain- ing treatment is assiduously adhered to. The average duration is a week, and cases vary in character from a mild fever, with gastric disorder, to a malignant and incura- ble typhus icterode. There is no specific treatment. No depressing remedies should be employed. Cold and evaporating lotions to the head may prevent brain symptoms; ice, effervescing waters or champagne in small quantity, and other remedies for com- posing the stomach, are valuable. Carbo- nate of ammonia may help to oxygenate the blood. But "the Spanish method"— quiet, discreet nursing, warm drinks, and blanketing, and, later, abundant nutrition —is found to be the most successful means of cure. The mortality varies with the character of the epidemic, the class of per- sons it has attacked, their hygienic sur- roundings, and the discretion with which cases are treated; it may be as low as 5 or as high as 75 per cent. Zymo'sis. See Zymotic Diseases. ZymoFic Diseases [Gr. fi^ow, to "fer- ment"], those diseases which, gaining ac- cess to the human system, whether by infec- tion or contagion, through a small amount of materies morbi or causative germ-matter, thereafter develop or multiply this substance in the blood, each for a definite period of in- cubation, at the end of which the disease man- ifests itself. Thus, smallpox has a latent or incubating or formative period of twelve to fourteen days; typhoid fever has a forma- tive period of seven to ten days, measles of eight to twelve days. During these periods of latency, zymosis, or multiplication of the disease-germ in the blood and throughout the body, is thought to progress. v?.. :• c< c ■ tr c Cr. c:< c c <: , < c c. c c <* ' C c c <-_■ a <..-.{ : « ^ <^ ' C■ c■ • is. c f <* c c CC < <-, • < . c c f c • < c c ^ C < r ^ «C C v Co y; c *:. C c: . C, c c ' « c X.' 'C^.c <_ < -, E «C ■«- c c'. «c dc. .r •c cc: c c • < 5" c««: .c . c Cj. C C Cli cs. 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