V,'.V,V.VK. iV/.'.'.'/.v. ,'.\W/,V>V ' ■ ■ ■'.' '.•s/.'.Vrts.. »*£.'/.w.v.v.'.■,';,', -.-.'.'.'.-.'A/.- >//. '.:• *'////■/>'. //■'>'•'///* :«:W:%S....... H SCrfrs,.................. ^ \] No.3 iT/.£> L. c A PRIVATE TREATISE ON VENEREAIi DISEASE, GONORRHCEA, &c. &c. the private chest complete. tThe chest complete contains the book Jilted, in the lid,—the medicine for the Venereal disease,—the medicine for Gonorrhoea,—the Patent Syringe,— and ingredients for injections,—price $15. A smaller chest containing the medicine for Gon- orrhoea alone, together with the book, patent sy- ringe, $c, is $10; and one containing the medicine for Venereal alone, with the book, is $10. The book alone is $1. The whole is fitted in a little mahogany chest not larger than a small book, with lock and key, and is conveniently and privately forwarded in the form of a package to any part of the United Slates, the West Indies, or elsewhere. THE PATENT SYRINGE BAG. A. The bottle open. B. The pipe. C. The cap. D. The syringe filled. The. Injections are made by putting one of the powders into the bag, and filling it with water j the pipe is then screwed on, and over this cap, for the purpose of carrying it in the pocket. Entered according to an Act of Congress, in the year 1840, by Joseph Ralph, M. D. C. C. & E. Childs, Jon. Printers, 80 Vesey st. New York. A PRIVATE TREATISE ON VENEREAL DISEASE, IN TWO PARTS. The First on Gonorrhoea,—vulgarly called clap. The Second on Venereal, properly so called. Adapted to the use of every one, but more especi- ally designed for those whoa|e delicately circum- stanced and require a private as %ell as a speedy cure. . " . V BY JOSEPH'j^ALPH^.D. Graduate of the University of Edinburgh;—Member of the Royal College of Surgeons, London ;—and author of " The Family Physician." &c. &c. SECOND EDITION,—Greatly Enlarged. Sold by the author—Dr. Ralph—38 Courtland street, JV. Y.: who may also be consulted confidentially, by post or otherwise, on those various and delicate circumstances and dis- eases which relate especially to sexual weakness in either male or female. The consultation fee is five dollars, but this is not expected when the little chest, &c.—described in page 121 — is requested. we \4~Q INDEX. RW3p __ 1840 Introductory remarks,—which should be read by every one. Page. CHAP. I.—On Gonorrhoea,—Its nature, symptoms, progress, and consequences. - - 1 CHAP. II.—On certain diseases which resemble ■ Gonorrhoea in some respects, and are fre- quently mistaken for it, but which are totally distinct and different diseases. - 2 CHAP. III.—On the remedies in general use both in Gonorrhoea and venereal disease - 28 CHAP. IV.—On Gonorrhoea,—Its treatment and cure. 55 CHAP. V.—On Gleet,—Its nature and cure. - 68 CHAP. VI.—On Stricture,—Its symptoms, nature, consequences and cure. 77 CHAP. VII.—On Gonorrhoea in the eyes, and Gon- orrhoeal Rheumatism. - 105 CHAP. VIII.—On Gonorrhoea in Females. - « 114 CHAP. IX.—On venereal disease, properly so called,— Its distinguishing marks, its nature, pro- gress, and general principle of cure. - 123 CHAP. X.—On certam complaints which resemble venereal disease, and sometimes arise from sexual intercourse, but which, never- theless, are not venereal, nor can be treated .as such without the greatest dis- advantage. Persons affected with these complaints are often cruelly imposed on by advertising people. - 137 CHAP. XI.—On the use and abuse of Mercury, with rules for its proper management in the cure of venereal disease. - - - j 55 CHAP.—XII.—On venereal disease,—Its treatment and cure. - - t - 195 CI HAP- XIII —On venereal sore throat, CHAP. XIV.—On venereal blotches and eruptions on the skin. - 223 CHAP.—XV.—On Venereal in the Bones - 230 CHAP. XVI.—On the effects of Venereal on pos- terity, &c, 249 INTRODUCTORY. If it were only for the purpose of knowing as much of this disease as to be able to distinguish it from others, (for there are several diseases which resemble venereal in some respects, but are not so in reality;) or, in case it should be, to be enabled to fix upon the best and most convenient way of cure- ing it, instead of being harassed and deceived by a certain class of people, by whom the spirits and the health are loo often broken down and ruined, these alone would afford sufficient reasons for pub- lishing this little private volume. There is howe- ver another, and one of infinitely greater weight—the effect of this disease upon posterity. It is a fact which no intelligent Physician will deny, (nor, with ihe ex- ception only of a heartless, advertising quack, would any human being disregard) that, venereal disease, not properly cured, may lie so dormant and unsuspected in the constitution as to show it- self in no other way than in its fatal influence upon children. Now, to show my reader how he may detect the imposter who wishes to make-him believe he has the venereal disorder when he really has not: or, if he really have it, to enablejhim to fix upon the best, and most convenient, and private way of curing it, is the object of this little volume, and this I have attempted in the very plainest words and manner. For the purposes of clearness and convenience it appeared desirable to arrange it in chapters ; and here it is my intention to state the subjects of them, seve- rally, and just to mention some of the most important parts of each, so that, on running over these intro- vm. INTRODUCTORY. ductory pages, any one may fix at once on whatever may appear most useful to hirnself. The first chapter—is,, on the nature, symptoms, progress, and consequences of Gonorrhoea—vul- garly called clap. This should more especially be read by those who do not know that Gon- orrhoea and venerealj are two disiinct' and dif- ferent diseases, requiring very different modes of treatment. It will be also seen that Gon- orrhoea is sometimes a very difficult and tedious complaint to cure, requiring much skilful and pa- tient perseverance in the use of proper means ; at other times it will yield more kindly and quickly, al- most to any of the usual remedies. No doubt, most of the tedious cases met with are the consequence of taking certain pills and drops which are daily adver- tised ; and others, again, are owing to peculiarities of constitution—being unfavorable to a speedy cure ; but by far the greatest number of these bad cases arise from the want of knowing something of the nature and progress of the disease itself, so that the proper remedy should be taken at a proper period, and under certain circumstances only. These cir- cumstances therefore in this chapter are carefully pointed out. The second—is, on certain diseases which re- semble Gonorrhoea in some respects, and are fre- quently mistaken for it; but which, nevertheless, are totally distinct and different diseases. This is a subject of the deepest interest, particularly as there is a class of persons, who, either from ignorance or knavery, call every thing they see upon these organs venereal. It is not however, as I have there observed the being thus cajoled and put to inconvenience and' expense, whjch is the worst of this, but it often leads INTRODUCTORY. IX. to painful and most unfounded apprehensions and suspicions. I have known it to interrupt the happiness and even threaten the disunion of virtuous couples. The third chapter—is on the remedies in gene- ral use both for the cure of Gonorrhoea and vene- real disease. It seemed proper, before entering on the cure of these diseases, to explain the value and proper use of such remedies, especially as I have often found that many had been taking medicines in one of these complaints, which was intended for the other; and also, because the same medicine which is useful in one may be absolutely useless and injuri- ous in the constitution of an other. But here I cannot pass without a word or two upon a fact which I am certain will be granted by every thinking man,—I mean the absurdity and wickedness of selling any one a box of pills or bottle pf drops for the indiscriminatecure of these complaints, and under all the various circumstances which may attend them. These circumstances I have shown to be nume- rous and important, arising as they do from habits of life, age, sexes, and peculiar kinds of constitution. In fact, the circumstances which may at any time occur in the course of this disease, but which do not properly belong to it, are far more dangerous and distressing than the disease itself.—In this chapter, also, is the nature of injections,—their safety, effica- cy, and sometimes indispensable necessity, is ex- plained. I have also here described my pocket, gum elastic syringe,—contrived for the purpose of conve- nience and privacy—the value, simplicity, and con- venience of which can scarcely be conceived with- out referring to the plate, page 43. The fourth chapter.—This is on the cure of Gon- orrhoea.—The nature of Gonorrhoea and its reme- X. INTRODUCTORY. dies having been explained, its cure is now exceed- ingly easy to understand and manage. Not that it is necessary for every one to read these chapters severally, on the contrary, it is sufficient only to pe- ruse this single one on the cure of this complaint; most people however feel a pleasure in being ac- quainted with the principle on which their cure proceeds, as well as with the fact itself. The fifth chapter—is on Gleet—a consequence of a badly treated Gonorrhoea. On this subject the remarks as to whether a gleet retains the infec- tious nature of Gonorrhoea or no, are well worthy of attention, especially as some very erroneous notions are entertained upon it. Many a person has unintentionally involved others in this complaint in consequence of such errors. This indeed I have felt to be of so much consequence as to take the greatest pains to place it in its proper light; and, that I might put every one seriously on his guard I have given the opinion, and also the very words, of one of the greatest Surgeons in the world upon the subject—Sir Astley Cooper. The sixth chapter—is on stricture—a subject than which there is none of more importance in the whole range of venereal maladies. It is also one which affords the richest field for all imposters. Here you will find them persuading unsuspecting people to take their drops or pills, or some such thing, for months together, while every real Phy- sician absolutely knows that all the medicine in the world, alone, would never cure it. This every one will see immediately on reading the remarks upon the nature of stricture. Here also he will see that the discharge which now and then attends a stricture, may perhaps be stopped, to return again INTRODUCTORY. XI. on some occasion of excitement, but that this is a a very different thing from curing the disease; and that perhaps it is better not to stop it, for in this case a person is more completely off his guard, and ismore likely to remain unconscious of it, even for years, or or until some of its remoter consequences draw his attention to it. Many persons have been to me with these effects who never dreamed they arose from stricture until it was explained and its existence proved to them. I have therefore spared no pains to make the nature of a stricture understood, as well as the symptoms which attend it; and it gives me plea- sure here to add, that, although I consider stricture to be the most serious thing that can possibly befall an individual, yet the means of curing it are sim- ple, easy, safe and certain ; hundreds under my own immediate care can attest this truth, many of whom have been cured in as many weeks as it had existed years before. The eighth chapter—is on Gonorrhoea in females, in which every necessary direction is given to ena- ble them to curl this malady in a speedy and private manner. The ninth chapter—is on Venereal disease, pro- perly so called. The necessity of distinguishing this from Gonorrhoea, together with its general principle of cure, are here most clearly pointed out. Tlie tenth chapter—relates to certain disorders which resemble venereal disease, and sometimes arise from sexual intercourse, but which, neverthe- less, are not venereal, nor can be treated as such without the greatest disadvantage, &c. &c. It is impossible to mention any part of this chapter XII. INTRODUCTORY. as more interesting than another. The heading of it implies the nature of the remarks it may be ex- pected to contain, and these must be read in con- nexion to be understood and properly appreciated. This, indeed, is the case with regard to every following chapter on venereal disease. I propose therefore, with one exception, to do nothing more than merely state the subjects of them. The excep- tion I allude to is— The eleventh chapter—in which the use and abuse of Mercury, with rules for its proper man- agement in the cure of venereal disease is given with every possible degree of plainness. As in Gonorrhoea, so of venereal, after describing its nature, and the circumstances which distinguish it from disorders that resemble it, it seemed proper, before entering on its cure, first to explain parti- cularly the nature and properties of its peculiar remedy—Mercury. I will venture to say few per- sons will read this chapter without shuddering at the idea of taking Mercury from advertising quacks. Well may they disclaim, as many do, the use of Mercury in their pills and drops; this pretention however I will explain, for it will enable every one to judge exactly of its value. As may be seen, (page 131) it was once suppos- ed that venereal disease could not be cured effectu- ally without the aid of Mercury; later investigations however, proved it could be. This admitted, the question then was, which was the best—the most ex- pedient plan ? Now, this latter discovery consisted, not in any new or particular medicine or remedy whichroad, and which discharge but very little matter; whereas, in this, the discharge is copious, and there is no ulcer at all—it is rather an excoriation of the skin than an ulceration. Now it is a grievious thing for a man to be told he has got a Gonorrhoea, and be treated as such, under circumstances like these. The truth is, this case is nothing more than a little alteration in the secretion of certain glands situ- ated under the fore-skin, occurring frequently in those who neglect to wash these parts, particularly in hot weather; and its cure is easily accomplished, simply by washing often in the day with Gonlard's Lotion, (sugar of lead wash) or brandy and water or even plain cold water—taking, at the same time, a dose or two of cooling physic. The next of these diseases is of more importance-__ it is one which occurs in females, and often gives occasion to many painful and unfounded fears Gonorrhcea,—Disorders which resemble ii. 15 for it approaches, in appearance, much nearer to Gonorrhcea. It consists of,— Symptoms resembling Gonorrhoea, communica- ted by Females in whom no appearance of diseaes can be detected, or who have only those complaints which are considered innocent and common.—This is a disorder on which I am very anxious to be plain and thoroughly understood. It occurs often in those who have a discharge resembling what is called the :' Whites," or " Weakness." Now the Whites is a disorder to which many females, both married and single, are subject. The discharge of it varies in quantity and appearance ; it may be much or little ; clear, or opaque and milky; thin and watery, or thick and adhesive. In one or other of these forms, how- ever, varying from circumstances, the Whites may continue for many years, proving to be nothing more than a secretion of what is natural to these parts, but increased in quantity or altered as above described. The circumstances which originally cause, and which vary this disease, are many,—such as weakness of these organs,—too great fulness of their vessels,— having children fast,—or too great excitement of the parts and others. But. although this disease, the Whites, may, and most frequently does, remain for any length of time without producing any correspond- ing malady in the other sex, yet, on the other hand, it may, and sometimes does, become infectious,— communicating the like disease to another person. 16 Gonorrhcea,—Disorders which resemble it. Now, the object of this chapter is to show that it does so, as it were, spontaneously,—that is to say, without intercourse with other, or infectious persons. The opinion that disorder, giving rise to symptoms resembling Gonorrhcea, may arise spontaneously in women, may be inferred from the circumstance, that such symptoms, now and then, occur in men of the most unblemished character and truth, and who could have received it only from their wives,—per- sons, also, whose age, habits, and religion, place them beyond suspicion. With respect to the former of these instances, I should think but few can have seen much practice in surgery or medicine, without having met with cases that would puzzle him to account for on any other principle. I will, however, state the outline of some as they have occurred to me.—A gentleman applied to me, for instance, and said—Sir, I have some strange symptoms of disease about me; and such, indeed, that if it were not for my confidence in another party, I really should suspect to be the symp- toms of a Gonorrhoea,for I once contracted that disease and know something of its nature. Well, I said, what are the reasons which lead you to determine it is not a Gonorrhoea ? He replied, the party I refer to is a lady whose word I could not question; besides I have known her long, and am quite certain that no consideration in the word would allow her to expose Gonorrhcea,—Disorders which resemble it. 17 me to the possibility of such a malady. And further still, having mentioned these circumstances to her, she denied it firmly, and is desirous even that some one should see her—so perfectly unconscious is she of having any such disease. Now, my inter- views on these occasions have often lead to two remarks—the first, that the female had no single symptom of this disease whatever;—and the next, that she was in the habit of being visited by another, and that he likewise was perfectly free from every symptom. These are important facts to keep in mind by those who have to form opinions of the real nature of these cases. But in my Note Book I have a still more curious case, and which I think is worth relating more particularly. It is this. A gentleman who had formerly been my patient, consulted me on what we took to be a Gonorrhoea, and at the same time re- quested me to see the lady, whom he had known some time, and who assured him she was perfectly free from any such disease. I did so, and found it ex- actly as she had stated,—she had no one symptom,— not even of a Gleet. However, we treated his dis- ease as Gonorrhcea—and though the cure was tedious, he at length got well. But, some time after, he re- newed his visits to this lady, and was again attacked with a similar disease—symptoms which differed in no other respect from Gonorrhoea, than in their mild- ness. After this, however, he kept away for a con- 18 Gonorrhcea,—Disorders which resemble it. siderable length of time, and, although in this inter- val he had interviews with other females without disease, yet, in renewing once more his visits to this lady, he was again, for the third time, attacked with all the symptoms of a Gonorrhoea. I know it may be urged in all these cases, that they occurred in females of a certain character, and therefore they might have been old cases of Gonor- rhoea, degenerated into infectious Gleet,—a disease which continues almost indefinitely,—is not attended with pain,—and in which there is frequently but very little discharge—not more, indeed, than many women (and females of this description in particular) are subject to. But to this I cannot consent, for two reasons ;—first, because these cases sometimes occur in women who afford no reason for believing ever had a Gonorrhoea; and next, because, if they had been cases of protracted Gonorrhoea—or Gleet—they would be infectious to every one alike, or very gene- rally so. Now and then, we know, a person may- have an interview with a female who has a Gonor- rhoea, or infectious Gleet, and may escape ; but this is an exception to a very general rule—it does not often happen. Likewise, that one individual is more susceptible of infection than another;—but this also is very limited,—the rule being, and pretty uniform it is, that, in such cases, the disease communicates to all. Here, then, while a common Gonorrhcea will effect all that come within its reach, or pretty gene- Gonorrhoea,—Disorders which resemble it. 19 rally so, this mild disorder, while it will effect some, will as uniformly suffer others to escape. It there- fore affords a striking difference in its consequences, and from this we may infer there is also a difference in its nature. My design in this section of my little book is to exculpate innocent and virtuous women from un- deserved and injurious suspicions. And this I ap- prehend to be an object of immense importance;— for, within the limits of my own experience I have met with lamentable instances of unjust suspi- cion ; instances too in which I am morally certain there was not a particle of truth, and which suspi- cion never would have gained possession of the mind if the subject had been better understood. With this view of its importance, I therefore deem it proper to place this fact upon the best authority in medicine which can be adduced. Now, I have al- ready shown that symptoms resembling Gonarrhea have been communicated by females in whom no symptom of the disease existed, or was ever known to exist; but these females were not to be consider- ed exemplary specimens of moral character, and, farther, I have stated them upon my own experi- ence ; I will now, however show, that the same thing happens in females of the highest moral character, and will show it also on the very best of medical authority. Here I might refer to the great 20 Gonorrhoea—Disorders which resemble it. John Hunter, Abernelhy and a multitude of others ; but, in that highly esteemed and learned work— Good's Study of Medicine,—there is a paragraph so clear upon this subject, that I cannot do better than transcribe it. In the fifth volume, page the 81st, after speaking of other diseases attended with a mucous or purulent discharge, which are now and then contagious, or infectious,—such as Dys- entery, purulent opthalmia, and others,— he says,— "In like manner, Leucorrhoa (which is the medi- cal term for 'the whites' in females) as we have already observed, has sometimes seemed to be contagious; for I have occasionally found a kind of blennorrhea (Gonorrhoea or Clap) produced in men, accompanied with slight pain in the urethra, and some difficulty in making water, upon cohabi- tation with women, who, upon inspection, had no marks whatever of luodic blenorrhoa, or clap; and, in some instances, indeed, were wives and matrons of unimpeachable character." This, at any rate, will satisfy the mind that such a thing is possible. With respect to the question,—how can a harm- less secretion be changed into an infectious one, this I cannot answer any more than I can tell why the discharge from Dysentery, or opthalmia, or com- mon catarrh, which are generally harmless disor- ders should sometimes become contagious. The structure of the membrane which is the seat of the disease in all these maladies, is exactly the same as Gonorrhcea,—Disorders which resemble it. 21 that which is the seat of the disorder in Gonarrhcea. It may be, and often is, no doubt, from neglect of necessary washing; and to this the habit of irregu- lar intercourse may give a greater tendency, for it is not to be denied that such instances are much more frequently observed in women of bad habits and in constancy than in virtuous persons; but this by no means proves that these are cases of genuine Gonorrhcea, nor that they do not now and then oc- cur in persons of a strictly virtuous character. With regard to the treatment of this complaint, it is exactly that of Gonorrhoea, for which, see chap. 4 —on the treatment and cure of Gonorrhoea. (Note 1.) It therefore appears, that symptoms very much resembling Gonorrhcea, and which are infectious too, may be received by cohabiting with females who do not present the least appearance of that disease;— that, although these are more frequently observed in females of lax morality and habits than others, they are alos known to occur, occasionally, in women of exemplary character—even in wives and matrons Note 1.—On this subject it general principles chiefly re- may be remarked that the gulate the treatment of them treatment of Gonorrhcea is all;-the first directs what- very much the same as that ever abates inflammatory of other diseases affecting symptoms, if any such ex- similar membranes,—as m ist; the second, such reme- oontagious Dysenteryt Op- dies as supercede specific ac- thalmia, &c. There is no tions by setting up an action specific remedy in any of of their own—precisely as J. m —such as Mercury, for The Black Pill" does in the instance, in Venereal. Two cure of b onorrhcsa. 22 Gonorrhcea,—Disorders which resemble it. whose habits, age, and religion, place them beyond uncharitable suspicion ;—and that, these complaints are cured by the treatment proper in the milder forms of Gonorrhcea.—A third disorder which lesembles Gonorrhcea, is,— Stricture in the urinary passage.—This, up- on excitement, will sometimes produce discharge exceedingly resembling Gonorrhoea, but without the, usual degree of pain and inflammation attending that complaint. What a stricture is, I have taken pains to explain in the 6th chapter. Here it is need- ful only just to say, it is a contraction, or a diseased condition, of some part or other of the urinary pas- sage, generally the consequence of a badly treated Gonorrhcea, but which often continues for a time so free from pain or any inconvenience, that it is not suspected to exist, and is only brought to light by the occurrence of some sufficiently exciting cause. Now, the act of sexual intercourse is a sufficiently exciting cause, and hence the disorder now referred to is frequently observed to follow quickly after it. I have often been consulted by persons who have re- marked they are quite unfortunate, for they scarcely ever are exposed without contracting this disease ■ and, what to them is most remarkable, is, that others who have visited the same female have escaped.__ The fact is, that this is not a case of Gonorrhcea at all, but of Stricture; and their friends have not these symptoms, because they have no stricture.. Of Gonorrhoea—Disorders which resemble it. 23 course, if such a person go to an advertising Knave, he will tell him immediately he has got a Gonor- rhoea ; and what is still worse, the medicines he may give him will be very likely to remove the symptoms, so that he will get the credit of curing a Gonorrhcea, But, in truth, he will no more have cured a Gonor- rhoea than he will have cured a Cancer; for, with purgatives and a low diet this discharge generally ceases in a little while. It would therefore seem exceedingly desirable to have some plain and positive rule to judge by in cases like the present, and, fortu- nately I have one to furnish. This rule is founded on the time when such symptoms first appear after connexion. The discharge I am now speaking of, that is,when it is from stricture, first appears within twelve or four and twenty hours after such excitement,—a period shorter than is required in the quickest case of Gonorrhoea. Now, Gonorrhoea may be compared exactly to inoculation. There is always a process and a certain time required, in order to produce the inoculated malady. It is true that some inocula- tions produce their proper symptoms sooner and more regular than others ; but, the usual time pecu- liar to each is generally known, and, unless delayed or interrupted by some peculiar state of constitution, is pretty regular. The usual period for the produc- tion of the symptoms of a Gonorrhoea is the third day after exposure to it. This however, is some- times delayed for several days by the causes I have mentioned; and, sometimes too, it is a little quick- 24 Gonorrhcea,—Disorders which resemble it. ened, but, as to its appearing in twelve, or fous- and-twenty hours, that it never does, and never can do. This then I consider a valuable fact,—it forms the basis of an excellent rule in practice,—the use of which may be seen by the following.—To a person for instance, consulting me on Gonorrhcea, I gener- ally put this question first;—How long is it since you were exposed? Now, if he should say, why, it is very recent,—it was only last night, and I ob- served some symptoms of it in the morning; or, at any rate, if he should state that it is within twelve, or twenty-four-hours after an exposure, I suspect at once it cannot be a Gonorrhoea. I then enquire if he ever had a Gonorrhoea before, and if he state he has, my suspicions are confirmed, and I explain my reasons for them. This of course leads to an exam- ination by the bougie, and then the truth is ascer- tained beyond the possibility of doubt, and he obtains a permanent and perfect cure. But thejvalue of this true and faithful explanation is greater than at first it may appear to be ; for it does not only undeceive and save an individual from paying different per- sons for pretended cures of Gonorrhcea, but it also saves him from the consequences of occult or hid, den Stricture,—an evil which I deem by far more serious and distressing than any to be found in the whole range of Syphilitic malady. The object of this little section therefore, is to show, that, among other causes capable of giving rise to symptoms re- sembling Gonorrhoea, a hidden dormant Stricture Gonorrhoea,—Disorders which resemble it. 25 is one,—that this is to be suspected whenever such symptoms appear within twelve or four-and-twenly hours,—but that this is only to be known for fact, by passing the bougie. Its treatment consists in a little cooling physic, rest, and low diet; if this is not sufficient, the usual treatment for Gonorrhoea will stop the discharge, but the only proper and permanent cure is the cure of the Stricture.—The fourth and last of these disorders resembling Gonor* rhcea, is,— .1 discharge occuring in female children,—and which frequently creates distressing apprehensions in the mind of parents. It consists in a discharge of matter from the genital organs, attended with some slight degree of inflammation and uneasiness. But this complaint in children does not originate in the parts themselves, but in some distant part, such as the gums in teething ; or in the bowels from foul and irritating accumulations there. This latter is no uncommon cause of the complaint. We know that irritation in the bowels in children is readily transmitted to distant parts, and is the cause of va- rious maladies. If this irritation happen to fall up- on the head, it produces dropsy of the brain ; or if on other parts, then other diseases take place, as sore eyes, or running sores from behind the ears, a swelling of the neck and others ; so, if it happen to fall upon the mucous membrane of the female organs. it then produces the disease we.speak of. It is not, 26 Gonorrhoea—Disorders which resemble it. however, that this disease in itself is of so much consequence, as it is the fear and misconceptions it may lead to. Filled with apprehensions, for instance, a mother takes her little child to some physician, and if he happen to be unacquainted with its real na- ture, these apprehensions are confirmed. Then suspicion falls on some one of having taken impro- per liberties with her, and she is threatened to con- fess. Perhaps, from fear of punishment, she may say that some one has. This would be very unfor- tunate, for such is the violence of prejudice on these occasions, that it would be totally unavailing to af- firm the contrary. I have read, somewhere, of per- sons innocently hanged from a misconception of the nature of this malady. With regard to the treat- ment of it, this of course is founded on the view here given of its nature ; remove the cause,—that is, scarify the -gums if they aTe inflamed, and cleanse the bowels with an active purge or two. Nothing more is wanted except plentiful and frequent wash- ing with cold water, perhaps sometimes with the addition of a little alum or sugar of lead. The following then, is the substance of all that has been said upon this subject. That, there are four complaints which in some respects resemble Go- norrhoea and are frequently mistaken for it. 1st,—- The natural secretion of the parts, which, collect be- neath the foreskin and becoming acrid, inflame and and excoriate the penis, producing a discharge;-~ Gonorrhcea,—Disorders which resemble it. 27 ,this however, does not come from the urinary pas- sage, but from the surface of the skin, and may easi- ly be detected by comparing it with what is said on Gonorrhcea. 2d,—A discharge more nearly still resembling Gonorrhoea, (and is infectious too,) is re- ceived by cohabiting with women in whom no symp- toms of this disease can be detected, and this, not only in women in whom exceptions might be taken to their habits and morality, but also in those of un- exampled moral character,—being wives and ma- trons, whose habits, age, and religion, place them at once beyond suspicion. 3d,—A discharge aris- ing from a dormant stricture which, upon excite- ment, now and then becomes the cause of similar symptoms,—is known chiefly by its quick appearance after sexual excitement;—-the proper and permanent cure of this, is the cure of the Stricture. 4th,—A discharge occurring in female children,—the result of distant irritation, chiefly of the gums in teething' and foul accumulations in the bowels. 28 Gonorrhcea,—Its Remedies. CHAPTER III. On the remedies in general use for .the cure of Gonorrhoea,—how far these are to be depended on,—to what particular cases they are suited,— and how to use them to the best advantage. The remedies for the cure of Gonorrhoea are very few in number and are pretty generally known. Not- withstanding this however, their real nature is but little understood, so that they are often misap- plied. They are, internal and external. Of the first, the Balsam of Copaiva—the Cubebs—and the Tur- pentines, are the chief; the external or local consist of Lotions, used as injections. These internal re- medies are vegetable productions, whose properties very much resemble one another. All of them im- part their virtues to the urine, which, being retained in the bladder, impress upon it their peculiar effect, and this again is transmitted to the part which is the seat of the disease—the urinary passage. On the other hand, Injections consist of certain suitable stimulants, which are applied by means of a little syringe, more immediately to the seat of this dis- ease. Both kinds are exceedingly valuable in their proper places, but they are also, both of them, either useless or dangerous if improperly used or misap- plied. The object of this chapter, therefore, is to explain their use and nature more particularly. Gonorrhcea,—Its Remedies. 29 It should be also stated, there are other reme- dies which are occasionally wanted in the cure of this complaint, but not always; these are, chiefly, the common remedies required to lessen pain and inflammation. Various things are used with such a view, but of such there are some which are far more suitable than others; a list of these therefore I will afterwards subjoin,—pointing out their proper use and dose, as well as make such other observa- tions on them as may seem required. I will begin with— The Balsam of Copaiva.—This, every body knows, is very often given for the cure of Gonorrhoea; indeed, this is so well known, that whoever discovers to another he has taken it, by the peculiar smell it gives the breath, is generally set down for one who is contaminated with Venereal malady. This how- ever is not the only objection to Balsam of Copaiva;— another is, its extreme offensiveness.to the taste ;— and a third, its offensiveness to the stomach, so that it is rejected by vomiting, or, if not rejected, it takes away the appetite and induces a degree of Nausea which can scarcely be endured. Indeed, it is a medicine, to some, so perfectly obnoxious that they cannot even think of the time of taking it without this Nausea or Vomiting. With respect to the two first of these objections however, (its offensive smell and taste) the latter of these may be avoided by taking it in Capsules—and the former partly so. These 30 Gonorrhcea,—Its Remedies. Capsules are made of little glutinous bags, which, being closed, contain a little of the Balsam. These little bags, when swallowed, are soon digested in the stomach, and thus the Balsam may be taken and its disgusting taste avoided. The peculiar smell imparted to the breath however is not got rid of by this means; for, especially when it disagrees, the stomach is continually expelling wind, and this af- fects the breath offensively and is equally betraying. But the most important of the objections to the Balsam of Copaiva (that of disagreeing with the Stomach and digestive organs) is not avoided by this ingenious way of giving it; for, when the Bal- sam disagrees, it does so whether it is tasted in the mouth or not. These things therefore, taken alto- gether, are gieat objections to the Balsam. But there are others still to be acquainted with. The first is, the fact, that there are many persons in whom the Balsam of Copaiva has no effect at all in curing this disease; and there are others where it will stop the discharge, so long as it is taken, but the moment it is laid aside, the running and disease returns. Now it is of no use for either of these to take the Balsam or to continue it alone, at any rate. If such were to take a ship load of this medicine,4t would never cure them. When the Balsam does good at all it does so very soon, by lessening the discharge. A good rule in taking the Balsam of Copaiva is, to watch its effect, and if it does not, within two days or three at farthest, very sensibly lessen the dis- Gonorrhoea,—Its Remedies. 31 charge, lay it aside, or add some other remedy to the treatment. There is also a time when the Balsam of Copaiva should not be given; this is when the inflammatory symptoms of a Gonorrhoea run high. We always look for more or less of these at the onset of this malady ; sometimes indeed they do not happen, but they should always be prepared for. It is with this view we always give an active purge or two, direct low diet, and rest, if it can be had, at the beginning of a Gonorrhoea. This sometimes prevents them altogether, and if not, it abates them. After an ac- tive purging medicine, therefore, if there is no great pain and heat in making water, you may begin with the Balsam; but, if there is, it should be delayed, however many days it may require to moderate these symptoms. Likewise, should you have commenced with the Balsam, and inflammatory symptoms at any time start up, lay it aside, and first abate them before you begin with it again.—I know that some begin with Balsam of Copaiva under any circumstances, and many times with strict impunity ; but I also know that when it has been given without attention to these circumstances, it has been followed by dis- tressing and even dangerous events—as inflamma- tion of the bladder, testicles, &c. 32 Gonorrhosa,—Its Remedies. But notwithstanding the truth of these remarks, the Balsam of Copaiva, where it agrees, and it is convenient to take it, is a remedy of considerable power in the. cure of Gonorrhoea. Sometimes it is trusted to alone, but then it must be taken for a length of time—for many weeks together. Let it be remembered, however, that, where it does do good, it does so quickly; perhaps in two days the discharge is lessened one half, and it then goes on "more grad- ually to diminish. But let it also be remembered, that in those cases where it is equal to the cure alone, that cure w^ould be effected in half, and less than half the time if given in connexion wTith local remedies—Injections, If the Balsam of Copaiva is fixed on as a remedy for Gonorrhoea, it should be given in the dose of about a tea-spoon full, in a little water or sugar, twice or thrice a day. With some it sets better on the stomach when made up in the form of mixture, the best prescription for which is given be- low—Note 2. If it happen to purge, omit it for a day Note 2.—Sir Astley Coop- er's favorite form for the Bal- sam of Copaiva was,—one ounce of the Balsam with one ounce of Mucilage of Gum Arabic, mixed in a bottle with four ounces of Camphor Ju- lep, of which a table-spoon full is to be taken twice or thrice a day. To some an ounce of any simple syrup, or Syrup of Ginger is an agree- able addition. It is very common to give the Balsam with an equal part of Sweet Spirit of Nitre, This however is not a good mixture—the Spirit of Nitre does no good and makes the Balsam very offensive t« some. Gonorrhoea,—/^ Remedies. 33 and take a dose of Rhubarb. If this will not do, give with each dose of it four or five drops of Lauda- num.—It should be continued for some time after the discharge has ceased, and then left off only by degrees. This is all that need be said about the Balsam of Copaiva,—the next of these remedies is— The Powdered Cubebs.— This is a species of mild aromatic pepper which is imported in large quantities from Java, and, as I understand, princi- pally for the cure of Gonorrhoea. It is an admi- rable remedy if properly availed of, and is free from the offensive smell of the Balsam of Copaiva; it is also a pleasant wholesome aromatic, and generally agrees with the stomach. Neither is there the same objection to giving it in the very onset of the disease (provided high inflammatory symptoms have not set in,) as there is to-the Balsam; indeed, such is its peculiar effect, that, if given freely and early, it sometimes supercedes these inflammatory symptoms altogether, and leads to a very speedy cure. If, bow- ever, inflammatory symptoms have already suddenly come on before you have had an opportunity of try- ing the Cubebs, it is then more safe and proper to reduce these symptoms by rest, purging, and diet, before you venture on this remedy. So also, if you had begun early with the Cubebs and such inflam- matory symptoms should happen to arise, let it be discontinued for a while, or until these symptoms 34 Gonorrhcea,—Its Remedies. have been abated by the means above referred to, and then resume the Cubebs. The best way of taking Cubebs is in the dose of a piled up table-spoon full, mixed in a tumbler of water, and repeated twice or thrice a day. It is of no use to take them in the dose of a tea-spoon full ai the time, as many do.—There is something also in the manner of mixing them. The best way is to all a tumbler half full of water, then put a table-spoon full of the Cubebs upon the water, and in a minute or so you will find they will have sunk from the surface to the bottom, and thus are equally diffused. If you adopt any other way of mixing them, they get in lumps,, which is very disagree- able. Should the Cubebs irritate the bowels as a purga- tive would do, this may be checked by adding five drops of Laudanum to eaeh dose; but if they only prove a little laxative, to this there is no objection. The virtue of the Cubebs should be separated by the kidnies and carried into the bladder, and of this you may always be assured when a peculiar smell is imparted to the urine,—a kind of violet smell,—not unlike that which the urine has on taking turpentine, or being exposed to a newly painted room. But, although I have said so much in favor of the> Cubebs, let it not be thought that they are to be de- Gonorrhoea,—Its Remedies. 35 pended on in every case. On the contrary, there are many individuals in whom they seem to have no good effect at all; and others in whom they will stop the discharge so long as they are continued, but the moment the remedy is laid aside, the disease returns. And what was said of the Balsam of Copaiva is also applicable to the Cubebs;—viz. when they do any good at all, they do it quickly; so that if you do not see the most decided advantage from their use in two or three days, but little or none is to be expected from them. The fact is, that many cases of Gonor- rhoea defy the virtues of internal medicines alone, and absolutely need the aid of local remedies. The inconvenience of its bulk is also another objection to the use of Cubebs.—This brings me to the subject of my favorite remedy,— The Black Pill.—The virtues of the Balsam of Copaiva and the Cubebs have now been fairly stated, and the objections to them shown. These objections are, first, to the Balsam, its smell, being peculiar strong and disagreeable—betraying the disease for which it is taken; also, its effect upon the stomach and the bowels, which is obnoxious and intolerable to many ; next, to the Cubebs, its bulky form—ren- dering it exceedingly inconvenient. To these again must be added, the uncertainty of their curative effect, for the influence of either of them alone is in many cases so small as to fail entirely in the cure of the disease. It therefore seemed desirable, if it 36 Gonorrhcea,—Its Remedies. could possibly be done, to extract the virtues of them both from their disagreeable and offensive parts and unite them in one compound. And more especially so, as it had been found, that, in those cases in which one of these medicines was not equal to the cure of this disease alone, yet, that when combined they frequently succeeded well. Modern Chemistry had also shown that the active properties of a vegetable medicine frequently resided in a very small portion of its bulk. The article Quinine, for instance, (taken from Peruvian Bark) is an example of this fact, for of this a quantity not larger than a pea is even more effectual in the cure of Ague, or any of those com- plaints for which the Bark is given, than a whole table-spoon full of the Bark itself. In this, after divers and repeated trials, I succeeded to my utmost wishes. At first I made this Extract in the form of Conserve, but, as some of my patients could not take a Conserve, and as, in very hot weather, it became too dry, I made it afterwards in Pills—which I call " The Black Pill." This medicine I have now used for three years, very extensively, and do not hesitate to say that it is by far the best internal medicine that can be taken for the cure of Gonor- rhoea. If contains the virtues of the Balsam, with- out its disgusting smell and taste; and of the Cubebs, without its inconvenient bulk; while, uni- ting the properties of both in one, it cures those cases which one of them alone so often proves un- equal to. Gonorrhcea,—Its Remedies. 37 Let it however be remembered, I do not recom- mend that the cure of Gonorrhoea should be trusted to internal remedies alone; certainly, the use of In- jections should co-operate,—the cure is then accom- plished in less than half the time, and far more safe and certain. But there are persons who are preju- diced against injections, and it is of great importance that such should have the best internal remedy. To such therefore the composition of " The Black Pill" is doubly valuable. I will only add upon this subject, that the same precautions that were enjoined on the Balsam and the Cubebs are requisite in the use of the Black Pill;— do not begin with them until high inflammatory symptoms, if any such exist, are abated by purgatives and low diet. The dose is five, or six, or more, three limes a day. They set agreeably on the stomach, and rather increase the appetite and strength than weaken either. Injections.—The use of these form an invaluable part of the treatment of Gonorrhoea,—it is applying the remedy to the disease itself—the advantage of which can scarcely be doubted. Yet there are some who are opposed to injections, simply, as it would seem, because they may be abused. But carry on this reasoning to other diseases—say Opthalmia, for instance. Internal remedies then, are very good in Opthalmia, and sometimes will cure it, but who would 38 Gonorrhcea,—Its Remedies. withhold the-use of Lotions and other applications to the eye itself, simply because they may be mis- used or abused. Is there a single medicine which may not be abused ? Quite the contrary, and the most valuable too are the most capable of such abuse. Oh, it is said, but they may cause a Stricture; and so may Lotions and Ointments put out the ey e; but, if properly used, they will save the eye, and cure its malady, and this in less than half the time it could be cured without them. Indeed there are many cases of the eye that cannot be cured at all without them, and so of Gonorrhoea. As to the idea of injec- tions causing Stricture, nothing can be more ridicu- lous ; for, on the contrary, they prevent them. The ultimate result of a Gonorrhoea, long continued, is Stricture. Gonorrhoea implies Chronic inflamma- tion,—this is its essential nature,—the ultimate ten- dency of which is to destroy the elastic principle with which the urethra is naturally endowed, and in this consists incipient Stricture. Whatever shortens the duration of Gonorrhoea, therefore, lessens the chance of Stricture. Now, Injections shorten the duration of Gonorrhoea; therefore, Injections prevent Stricture. If another argument were required, I might ad- duce the fact, that Injections are used and recom- mended by the greatest surgeons in the world. This however is quite unnecessary,—it is enough to state that, although internal remedies alone will sometimes Gonorrhoea,—Its Remedies. 39 cure a Gonorrhcea, yet they sometimes totally fail; also, that in those cases where internal remedies are sufficient to the cure alone, that cure can be accom- plished far more safely and certainly, and in less than half the time, if aided by Injections. It would therefore seem superfluous to say another word upon the utility of Injections,—it only now remains to show their proper use. Injections should not be used in the very early or inflammatory state of Gonorrhoea; and even when this is past, it is better to begin the cure with internal medicine, and continued this a day or two, before resorting to injections. After this you may use them safely and very advantageously,—few Gonorrhoea cases can long hold out against their proper use. Injections should not be used too strong. It is no disadvantage if it give a little tingling sensation, but if it amount to heating pain, its strength should be reduced by adding a greater portion of water to it. It is not proper however, on the contrary, to increase the strength of an injection to any great degree, but rather, if it seem to do no good, to change it for an- other. So, if any one which has been useful, but after a time should seem to lose its power, it would be better to change it for another than to increase its strength. Injections will sometimes lose their good effect, and for this reason several prescriptions are given for them. Indeed under any circum- 40 Gonorrhoea,—Its Remedies. stances it is better to change an Injection now and then—the part becomes accustomed to the pecu- liar stimulus of one alone if long continued,—the disease is sooner baffled and destroyed when one correcting stimulus is now and then exchanged for another. It is better therefore to change an in- jection; you may return if you please to the one you used at first, if that agreed, only change it now and then—keeping most to that which best agreed. Injections are chiefly mineral; there is a great variety of them, but they all act pretty much on the same principle; some however are better than others, and these are carefully selected in— note 3. I call them No. 1, 2, 3, and 4. The higher numbers may be a little the strongest, but it is not the strength, it is the effect of change, I lay the great- er stress upon; it is however always as well to be- gin with No. 1. Injections, to secure their great utility, require Note 3.—The best forms of grains of common alum dis- injecrions are the following, solved in a half pint vial of —at least they are the best water. that can be procured at any White IHtriol Injection.— apothecary's store. Sixteen grains of white vitri- Saturnine Injection.—For- ol dissolved in a half pint cf ty grains of Sugar of Lead water. dissolved in a half pint vial Blue Vitriol Injection__ of ram water. Eight grains of blue vitriol in Mum Injection.---Forty a half pint bottle of water- Gonorrhcea,—Its Remedies. 41 attention to the manner and frequency of using them. Many times I have heard it said, " The injection does no good," when I have found upon enquiry that it had not been made to enter the uri- nary passage. Of course it then must fail. To use an injection properly it must pass up a certain distance. No matter how much farther, but they must go up at least two inches, and it should be kept and retained there for -a minute or two, by pressing the top of the penis with the thumb and finger. The sensation an injection gives is quite enough to tell Avhether it has properly enter- ed—it is as if you wanted to pass out urine; but the proof of it is, that a teaspoon full or so squirts out again when you let go your thumb and finger.— With respect to the repetition of their use, this too is an important point,— much depends on their regular and frequent repetition. An injection should be used six or eight times in the four-and- twenty hours;—oftener if you please, if they do not irritate or pain, but certainly not less than I have stated. I know, that with the common syringe,1 this repetition of them was often quite impossible ; how could a person engaged in business and perhaps be- hind the counter for instance, retire often and pri- vately enough for such a purpose. And not only was a syringe to be carried in the pocket, but a bot- tle of injection too, and a cup to pour it out in. It was quite impossible for one in a hundred to comply with this as frequently as was required, and hence 42 Gonorrhcea,—Its Remedies. the use and value of injections was never properly ascertained. But these objections no longer now ex- ist, for with my patent pocket syringe next to be de- scribed, an injection may be used just as often as is needful and with perfect convenience and privacy. The Patent Syringe.—It is a little flat elastic bottle, holding two ounces, the neck of which is at- tached to a metallic ring. To this ring a little pipe is screwed, and over this again a little cap, so as to make it water-tight, and suited to the breeches pock- et. When you want to use the injection you have nothing more to do than unscrew the cap; and when you wish to refill it, put one of the papers of ingre- dients (Avhich are put up with the syringe) into the bottle by the ring, fill it with water, shake it, and the injection is made. Nothing can be more convenient and private ; but the woodcut on the following page will" show more clearly the use of this contrivance. Two of the patent syringes (in case one by any chance should break,) together with a set of the ingredients and a full quantity of the Black Pill, cfc. tf-c, are put up in a little chest, with lock and key,—having also the book fitted in the lid. This contains every thing necessary for the cure of Go- norrhoea, and is sent by Steam-Boat, or otherwise to any part of the United States. 7 he price is $10. A similar little chest containing every thing necessary for the cure of Venereal Disease, is also $10. But the complete chest, containing the medi- cines, $c, for both complaints,— Gonorrhoea and the Venereal—is $15. The book alone is $1. Gonorrhcea,—Its Remedies. 43 The Patent Syringe. A, the bottle open.—B, the pipe.—C, the cap.—D, the syr- inge filled. The preceding remarks relate exclusively to the remedies in general use for the cure of Gonorrhcea. But it was mentioned, there were other medicines now and then required, chiefly the common reme- dies in use for abating pain and inflammation. To make this little book complete, however, it is ne- cessary here to enumerate these and say a word or two upon the dose and proper use of each. Lotions.—These are often very useful, sometimes 44 Gonorrhcea,—Its Remedies. to assuage inflammation, and sometimes to assist the healing of ulcers,—for the manner of making and applying which, see note 4. Poultices.—Are more frequently required in vene- real disease than in Gonorrhoea—vide note 5. Cooling Emolient Drinks.—These are some- times very useful, and when they are required it is Note 4.—Sugar of Lead Lotion.—Sugar of Lead sixty grains to half a pint of water. some add a little vinegar.— The best way to use it, is to apply a fold or two of linen upon and around the part, and keep it wetted with it.— The part should be covered up as little as possible. Spirit Lotion.—One part of brandv and two of water, used as the above. Ulack Wash.---Is made with calomel and lime water, and is an admirable applica- tion in many sores, particu- larly those of a venereal character. To make lime water,—put a lump of lime as big as an egg into a gallon of water, stir it a little, and in an hour or two strain it off"the lime and keep it cork- ed. To a pint of lime water, add a drachm of calomel, and shake it well in the bot- tle, when mixed it will turn black. It is the black pow- der that is most useful, and to obtain that, hold a piece of linen to the mouth of a small bottle of the black wash and tu«i it downwards, some of the black powder will fall upon the lint which you then apply to the sore. Nitric acid Lotion.—From 30 to 50 drops of Nitric acid added to a quart of water.— excellent to some venereal sores. Note 5.—Common Poul- ice---Is best made with equal parts of crumb of bread and linseed meal boiled a few minutes ;n a sufficient quan- tity of water. It is one which will not dry and separate as bread and milk. i Grounds of Beer Poultice. —Made by using grounds of beer instead of water. Black Wash Poultice.— Crum of bread and linseed meal, with Black wash in- stead of water—used to spreading chancres. Carrot Poultice.—Boil the carrots well in but little wa- ter and mash them. It cor- rects the smell and agrees with many bad sores. Gonorrhcea,—Its Remedies. 45 important to know what are the best and Iioav to make them. But it sometimes happens, a person is so circumstanced that he cannot procure these—the request to have them prepared would lead to enqui- ries as to what they are wanted for. To such there- fore it will be satisfaction to know they can be donr without. In fact it is their diluting quality which is chiefly useful. The softening mucilagenous qual- ities of which they are composed, certainly has its use, but this is nothing compared with their diluting quality—depending entirely on the water on which they are dissolved. If therefore you take a watery drink of any kind, as common water, the end is answered—that is, if you take plentifully of it. From half a pint to a pint of water may be taken eight or" ten times a day—this is at the command of every one and it is of consequence to know it. A near ap- proach to these mucilagenous drinks however, can be easily and pleasantly made. Just take an ounce or more of gum arabic, in large lumps, in the waist- coat pocket, and consume it during the day ; put a lump in the mouth every now and then as you would do sugar candy ; it is a very pleasant thing and gives to the simple water drank the softening effects of the various drinks described in the following note 6. Note 6.—Barley Water.— three quarts of fresh water, To make this properly, take and boil it down to two a tea-cupful of pearl barley— quarts. Some add a few figs boil it a few minutes, then or a little liquorice root to- throw away this dirty water, ward the end of the boiling. and add to the pearl barley It may be repeated,—none of 46 Gonorrhcea—Its Remedies. Purgatives.—Next to bleeding, purgatives form the most active agent in reducing inflammation.— There is however, much in the selecting a proper purgative in particular diseases. The best that can be selected for the disease now in question, is the purgative Diuretic of my chest, next to be men- tioned ; but where this cannot be had, those men- tioned in note 7. may be substituted. these cooling, diluting fluids, can be taken to excess, in the early or inflammatory stage of Gonorrhcea ; and the oc- casion for taking them is just in proportion as the pain and heat in making water is great: when these have sub- sided, there use may be laid aside. Flaxseed Tea.—Take of bruised flaxseed, or linseed, (not linseed meal) two oun- ces, or two or th.ee table- spoonsful, (there is no occa- sion to be very exact in quan- tity) and put this to a quart of water, which is to stand simmering by the fire for an hour or two; then strain, and, if more agreeable, sweet- en it, and let at least this quantity be taken as com- mon drink during every 24 hours. Alkaline Drink.—Another excellent remedy to abate the pain and heat cf making wa- ter is the carbonate of pot- ash, or of soda. Procure an ounce of either of these, and dissolve one quarter of it in a qiiar of common tea, and take this quantity during the day. Soda water is also a good remedy, a glass may be taken three or four times a day. Note 7.—Epsom Salts— Is a good cooling purgative, an ounce is the usual dose, taken in water. This is the purgative that most people take on finding they have got a Go- norrhcea. It is not however the best; for much of that quantity of salts passes through the bladder- adding to the saline irritating quali- ty of the urine, and thereby increasing the scalding pain in urinating. It is better to take one of the rougher pur- ges below, but this will do if no other is at hand. It is not generally known that a very small quantity of Ep- som salts, if taken in a lar- ger quantity of water, will act more pleasantly, certain- ly, and effectually, than a larger dose in the usual quan- tity of water. A tea-spoon- ful for instance, in a tumbler of water, instead of an ouno« Gonorrhcea—Its Remedies. 47 The Purgative Diuretic Pill.—This is the pur- gative of my chest; it is the one I give generally and find it the most easy, comfortable and ef- ficient of any composition I ever met with. Five pills taken at bed time is the usual dose;—this ope- rates in the morning, and those Avho take it seldom fail to speak of its excellent effect. It may be taken also with great advantage in. almost any disorder in which a cleansing purge is necessary, particularly where the stools are of an unnatural color and arr offensive. Opium.—Is a valuable medicine under many cir- cumstances. The usual dose is one grain in the in a small tea-cupful of wa- ter. Also, by repeating this weaker solution.of salts, it is a very cooling and proper medicine in a hot and fever- ish state. But the best of all medicines for cooling, re- ducing, and preparing the system for a mercurial course, as in venereal dis- ease, is to combine Epsom 6alts with antimony, as in the following. Epsom Salts and Antimo- ny.---Add two ounces of Epsom salts and two grains of tartarized antimony to half a pint of hot water, and take a wine glass full of it two or three times a day, or as often as may be neces- sary to keep up a moderate degree of purging. Senna and Salts.—Is an excellent purgative medicine either alone or taken in the morning after a dose of Calo- mel the night before Take a handful or an ounce of senna leaves, and one ounce of Epsom salts, and add them to a little more than half a pint of boiling wa- ter, and when cold, strain it and take a tea-cupful for a dose. (A little bruised gin- ger would^warm and prevent its griping, which all purga- tives will sometimes do.) Jalap and Calomel.—Fif- teen grains of the former and five of the latter, taken in sugar or molasses. A lar- ger dose is sometimes given. Seidlitz Powders.—Is a pleasant way of taking a mud dose of Saline medicine. 48 Gonorrhoea,—Its Remedies. form of a pill; but it is given in different forms.— See note 8. Mercurial Medicine.—Of this there are many preparations, but for the most useful, safe, and con- venient of these—See note 9. Note 8.—Laudanum.—Of this the dose is from five to thirty, or fifty drops. Dover's^ Powder,—Is giv- en to assuage pain, it is a soothing and fever medicine —the dose is from two and a half to twenty grains. Note 9.—Mercuri(d Medi- cine.—Calomel and Opium.— Calomel sixty grains—Pow- dered opium fifteen grains —made into forty pills, of which two may' be taken every night, and sometimes one in the morning. The Blue Pill.—Is a mild and very excellent prepara- tion of Mercury, as well in other diseases as in venereal. The dose in the latter is ten grains at night and some- times five in the morning.— The dose however is regulat- ed by various circumstances, all of which are carefully re- ferred to in chapter nth— "On the management of mercury." Blue Ointment—Is anoth- er excellent form in which to exhibit mercury and is pre- ferred by some, eminent sur- geons, to any other; but the trouble and inconvenience, as well as the soiling of the linen it gives rise to, is an objection to its general use. When this is fixed on, from half a drachm to a drachm is nibbed into the thigh every night, and sometimes night and morning. But in the manner of using mercu- rial ointment I must be more particular. In the first place, it should be rub- bed in by the patient himself, but, if from debility or any cause he should not be able, then those who rub it in should have their hand guarded .with a bladder, and the best way to fix it is the following. Get a pigs' blad- der, and after being steep, ed in warm water turn it inside out; then soften it well with lard or sweet oil, and put it on the hand like a glove, ty- ing it round the waist with a piece of tape. Still it is bet- ter that a patient rub it in himself. Take therefore a quarter of the quantity to be used in the hollow of the hand and rub it briskly up and down the inside of the thigh till it has entered the Occasional Remedies. 49 Corrosive Sublimate.—This is a very active pre- paration of Mercury, and should be used only in urgent cases. There are forms of venereal disease however, which require a very quick effect of Mer- cury ; when it attacks the throat or nose for in- stance, in some constitutions, it spreads so rapidly, that, if we were to wait the slower operation of the milder mercurials, it would eat away the parts be- fore the Mercury could be brought to act upon it ; and it should be known, that, when the soft parts covering the roof of the mouth or the thin bones of the nose are once gone, they do not grow again— they are gone forever. It is therefore most desirable skin, when the hand will not pass so smoothly ; then take another quantity, and so on till it is all rubbed in. It is common for it to make the thigh a little sore, or to bring out a crop of pimples on it by rubbing; in this case change the thigh, and if the same thing happen again take the inside of the arm ; any part will do where the skin is thin. It is a good thing also to wash the old ointment off now and then with soap and water — the skin will take the oint- ment better for it. The rub- bing may be either night or morning. Throughout this course of rubbing, wear a flannel pair of drawers next the skin,—-the same pair the whole of the time. The Specific Pill.—But far better than the Calomel, the Blue Pill, "or the Blue ointment, is the compound called "The Specific Pill," which is contained in the chest for venereal. It is a mild mercurial, and one which always agrees. I have used it now for many years and can depend on the mercurial action of this med- icine better than any other. It is continually referred to in the pages of this little vol- ume. But, use what form of mercury you will, it is some- times quite necessary to have the aid of another, and then I prefer the Blue ointment in addition to my specific pills ; this necessity however, does not often occur. The usual dose of the " specific pill" is two at night and one in the morning. 50 Occasional Remedies. to have some remedy that will very quickly put a stop to its progress. When this is done, however, this active medicine should be laid aside, and the cure completed with a milder and safer preparation. It is not a remedy to be relied upon for the cure of this disorder, as it is to check and arrest it when the destruction of important parts are threatened, and this it will speedily do. An eighth, or at the ut- most, a quarter of a grain may be taken three or four times a day; but for the manner of taking it more particularly, see Note 10. Fumigating.Mercury.—This, like the corrosive Note 10.— Corrosive Subli- mate and Muriate of Ammo- nia, (Sal Ammoniac.)—Of each six grains—dissolve themin sixty drops of water, then add crumbs of bread enough to make into forty eight pills—One of which will contain an eighth of a grain, and may be taken two or three times a day. But if a larger quantity is to be made, the following prescrip- tion is better, as the crumb af bread would become too hard and perhaps would not dissolve, in the stomach.— Corrosive Sublimate twenty grains—starch half an ounce —Gum arabic, two drachms —water enough to make into a mass for one hundred and forty-four Pills-each of which will contain one eighth of a grain of Corrosive Sublimate. Some add one drachm of Opium to the mass—it pre- vents griping. The best time of taking them is after meal. If a liquid form is preferred —then'dissolve one grain of the Corrosive Sublimate and one grain of Muriate of Am- monia in four ounces of dis- tilled water—and take the eighth part (a table spoonful) for a dose. Any pleasant syrup may be added if agreea- ble. The Muriate of Ammo- nia makes it dissolve quicker in water. Avery excellent Tonic and anti-venereal medicine in scrophulous and weak con- stitutions is one grain of the Corrosive Sublimate to one ounce and a half of the Com- pound Tincture of Bark, of which one twelfth, or one eighth pa; t, taken m a glass of water twice a day Occasional Remedies. 51 sublimate, is chiefly valuable in cases of spreading venereal sores, particularly of the throat and roof of the mouth, and, when it has attacked these it is in- deed, a.valuable remedy. Its effect is much more speedily seen than that of the sublimate, but the manner of using it, hitherto, has involved so much trouble and impossibility of privacy, that, invaluable as it is, it has seldom been availed of. The prepa- ration used for this purpose is the Red Sulphuret of Mercury, (red cinnabar.)—The directions for using which, have been the following:—take a red-hot com- mon heater and place it on a brick;—then throw on this half a drachm of the red cinnabar, when fumes will instantly arise ; these are directed to the throat or nose by breathing in the fumes through an in- verted funnel held over them. In this manner fumes may be applied once or twice a day. This plan however, will instantly be seen to be quite impossible with many without betraying for what purpose it is done, and therefore the following con- trivance which I call a fumigating candle, will be estimated highly. Fumigating Candle.—For this contrivance I am indebted to a late work on "Venereal disease by Mr. Colles, an eminent surgeon of Dublin. This plan of fumigating by the burning of a candle is rather hinted than described, but its real value struck me so immediately, that I lost no time in putting it in practice, the result of which proved most satis- 52 Occasional Remedies. factory. The plan adopted is to combine the cinna- bar with wax, and make of this a candle of the com- mon size, an inch or two in length, divided by a line around it into four parts. With this there is nothing more to do than 10 light the candle and inhale the smoke arising from it, this contains the Mercury in sublimation,—a penetrating way of applying Mercu- ry to parts otherwise of difficult access, and which has a most immediate effect. It has also an excellent effect on the female genital organs, as well as on sores which frequently occur about the fundament. For this purpose the candle is placed in a cham- ber utensil, or night stool, over which the patient sits awhile. When the candle is burnt down to the line it is to be blown out. Each candle, an inch or two in length, contains four mercurial fumigations. It is a most convenient and speedy way of arrest- ing venereal in these parts. I have effectually stop- ped the progress of it in the throat in 12 hours; and have cured excressence and sores about the anus in as many days as they had existed months before. Bark.—Occasionally, in the treatment of Vene- real disease especially, it is necessary to support and re-invigorate the constitution. In cases of great weakness, or when a venereal sore takes on a spread- ing and unkindly character there is this occasion.— Nothing succeeds better in these instances than the Peruvian bark,—sometimes alone, but more general- Occaeional Remedies. 53 If combined with remedies such as are mentioned in note 11. SarsapariUa,—Is a well known valuable medi- cine in the treatment of Venereal disease. Not that every case of Venereal requires sarsapariUa,—far from it; but there are. states and conditions of the consti- tution exceedingly unfavorable to mercury, (the specific remedy) but which by its aid, are rendered capable of bearing mercury well. There are also conditions of the constitution in which it is advantageous to give the sarsapariUa and the mercury together,—the constitution bears the mercury better, and the disease is more com- pletely and more certainly cured thereby. It will be seen therefore, that the sarsapariUa is not given to cure the venereal,—it has not the power for this,—but it enables the constitution to bear the mercury which will, and this under such circum- stances which would render it dangerous to give, or to continue that remedy without it. It is true, venereal symptoms will disappear under a course of sarsapariUa alone, but they will return. This Note 11.—If the Bark alone is the following :-Decoction is given—a teaspoon full of of Bark, half a pint—Volatile the powder in a glass of Ammonia, two scruples- wine or wine and water, is a Compound Tincture of Bark proper dose—and repeated —Six drachms. Tincture of two or three times or oftener Opium, one drachm, of which in the day. Another way of a.wine glass is a dose, taken taking the bark—especially every third or fourth hour. jn unkindly spreading sores 54 Gonorrhcea,—Its Remedies. fact experience abundantly confirms. Innumera- ble cases are on record, where, under the sarsa- pariUa, the symptoms of venereal in the constitution have disappeared, and returned again and again, until at length a course of mercury has been entered on. when they have disappeared forever. Remember, therefore, sarsapariUa is not giv- en to cure venereal disease, but only to enable the constitution to bear that remedy which will ; also, that sarsapariUa is not required in many cases, but only in those of weak and irritable constitutions, or in those in whom mercury is found to disagree—render- ing the patient feverish and irritable. With respect to the manner of taking sarsapariUa. many preparations of it are in use; some of them are very troublesome, inconvenient, and expensive ; and it does not seem to me, that these latter have any great advantages above the former. The most simple, convenient, and least expensive is the pow- der ;—a good large tea-spoonful of which, in milk and water, I have found, as far as I could see, to answer all the valuable purposes of this medicine ; but in note 12, I wiU give the other forms, leav- ing it to circumstance or partiality to fix on either. Note 12.----The Powder in a tumbler of milk & water, of SarsapariUa, is taken in or in any thing more agreea- doses of a teaspoonful mixed hie-three or four times a day. Gonorrhoea—Treatment and Cure. 55 CHAPTER IV. On the Treatment and Cure of Gonorrhoea. It is reasonable to suppose that those who have read the preceding remarks on the ordinary reme- dies for Gonorrhcea, will prefer those I recom- mend to any others. These are put up together in a little chest—including my pocket syringe, on which Simple decoction of Sar- sapariUa,—may be made in this way. Boil two ounces of the sliced or bruised root in three pints of water till it is reduced to a pint and a half (which is a wine quart bottle), after boiling an hour or two, it is recommended to take it out of the water, and bruise it again in a mortar- then finish the boiling—strain it and fill a wine quart bottle with it. This quantity should be drank daily—half a pint at the time. As a larger quan- tity can be made with but little extra trouble, most will see the advantage of making two or three bottles at the time. Some make the proportions of the decoction stronger, but this I take to be the medium and the best. But there is an easier way of ma- king the simple decoction,—it is by boiling three drachms or the Extract of SarsapariUa for a few minutes in a pint and a half of water. The Compound Decoction of Sarsaparilla.-This is of the same nature as the famous Lisbon Diet Drink or Decoc- tion of the Woods, and is made by adding to the sim- le decoction a pint and a alf of the following ingre- dients ;—Guaiacum rasped, sassafras and liquorice root, of each two drachms, me- zereon root, one drachm : then boil them together for about ten minutes and strain again. Te be taken as the simple decoction. Syrup of SarsapariUa.— This, if you can get it good, and with a proper portion of the extract, is a pleasant way of taking it,—from half, to a full wine-glass may be taken in a tumbler of water, three times a day,—or it may be added to either of the decoc- tions to make them stronger. 56 Gonorrhcea—Treatment and Cure. so much convenience and utility depend. But beside being more convenient and certain, they will also be found cheaper in the end than procuring medi- cine from time to time at any apothecary's store.— In this chapter on the treatment and cure of Gonor- rhoea, therefore, I shall refer continuaUy to the reme- dies of my chest; but as this may not be in the possession of every one, I shall also refer to those other, though inferior remedies, already mentioned and described. A Gonorrhcea, as stated in the second chapter. commences with a discharge from the urinary pas- sage, attended more or less with pain and heat in making water. These symptoms generally appear in about two or three days from the period of expo- sure to it. There are also other circumstances which may or may not appear, and may be therefore called occasional symptoms; these are,—excessive pain in making water,—swelling of the foreskin,— swelling in the groin,—painful erections of the pe- nis,—and swelling of the testicles. Now, the treat- ment under all these circumstances must be consid- ered ; but it will add to the plainness of the subject if these be considered separately. I will therefore first describe the treatment of the simplest case of Gonorrhcea, and when that is done, will take those other circumstances—or occasional symptoms, in ro tation. Gonorrhcea,— Treatment and Cure. 57 In every case of Gonorrhcea there are two distinct and separate stages ;—the inflammatory or painful, with which it begins ;—and the specific, or that con- sisting in a continuation of infectious discharge, but without much pain and inflammation. It is true, that in some cases, the first, or inflam- matory stage is very slight, but there is always something of it, and though there may be scarcely any,rit is always right to guard against it. For this reason I recommend that in every case of Gonor- rhoea an active purgative should first be given. Take five or six of the purgative diuretics of the chest, or any other in note 7 you please. If the pills are taken at bed time, they will probably operate briskly in the morning, if not, repeat the dose. But if, not- withstanding their purgative effect, low diet, a free use of some cooling drink, (note 6 ,) and as much rest as you can command—the pain and heat in making water should come on, or, having already been complained of, should increase, it will be proper to repeat the purgative again, before ad- vancing further with any other remedy. This pain and heat, if at all considerable, must be abated first. I will suppose, however, that a purgative dose or two being taken, it is very moderate, or, if it had been pretty severe, abated, that now therefore is the time to commence with other remedies, to begin to lessen the discharge. Begin with the black pill, $8 Gonorrhcea,— Treatment and Cure. five or six of them three times a day. In a day or two it is probable the discharge will lessen ; but whether it do or not, provided the pain and heat in making water should not return, begin with the in- jections precisely as mentioned in page 37. There is no occasion to enlarge this little book by repeating these directions here,—they are given in the fuUest and plainest manner. At the same time continue the black pill. Under this plan, sooner or later (but remember it is not equally soon in every case) the discharge will cease entirely. When this happens leave off the pills, or take but half the dose a few- days more, then leave them off entirely. Next, begin to lessen in frequency the use of the injections, but do not leave them off too suddenly. One of these remedies (the injection or black pill) should be continued for 10 or 14 days after the dis- charge has disappeared. If the case should happen to be more tedious than common, the pill may be omitted—more than are contained in the chest need not be taken—the injections will finish the cure of it alone.—This is the treatment of Gonorrhcea in its simple and common form ; but, as I have said be- fore, there are other circumstances which may or may not occur, and which must now be mentioned separately. Before however finishing these remarks on the cure of Gonorrhcea,—it may be as well to say a word or two on the difference there is found in the Gonorrhcea,— Treatment and Cure. 59 time of curing this complaint in different individ- uals. Even under the same degree of active and judicious treatment, and this especially adapted to each peculiarity of constitution, the time required in one will be ten times longer than in another.— Neither is it always easy to foretel the individual in whom the cure will prove so tedious. The fact itself however, is noticed by every author* of experience, and it is well to know it, that such cases may be endured with patience and persever- ance. As an instance of good authority for this statement, I will here transcribe the words of Sir Astley Cooper on the subject:—he states,—" Go- " norrhcea sometimes continues for so long a time, " notwithstanding all the means which may be em- " ployed for its cure, as to be an opprobrium to our "art." Again, " Gonorrhcea is a disease which-very " often baffles the longest experience, and the great- " est professional skill." And, he remarks still fur- " ther on this subject,—" You will generally find the " cure of Gonorrhoea difficult in proportion as the " constitution of the patient is disposed to Scrophu- " lous affections. If a patient has pimples in his " face, enlargement of the glands of the neck, a thin " delicate skin and irritable fibre, you may expect to '' have great difficulty in curing him of Gonorrhoea," Now, if this be true (and no one of much experi- ence will doubt it) who ean wonder at the fre 60 Gonorrhcea,— Treatment and Cure. quent cases of misery, disappointment, Gleet, and Stricture, which result from trusting to that swarm of advertising people who fill our little daily papers; for, if Gonorrhoea may prove so difficult under men of so much faithfulness and skill, what can be ex- pected from persons of the description I allude to. There is however one advising hint I cannot forbear to give to those who are laboring under a long contin- ued Gonorrhoea;—be sure that the person whose care you are under is a man of integrity and skill; do not be dissatisfied merely because the case is tedious, but be satisfied its tediousness is not the consequence of ignorance. Neither pay the least attention to what you may have heard of his curing other persons ; for, as I have shown in a former chapter, Gonorrhcea is sometimes of most simple and easy cure, and many of these are not cases of Gonorrhoea at all, though they are sure to call them so. Nor, in your enquiries, should you ever trust to what they say about themselves. If it were not too serious a subject, it would be quite laughable to read the long imposing titles which some of those will give themselves ;—but rather enquire of some re- spectable physician as to who and what they are 1 —I do not hesitate to say, there are no two diseases in the whole range of medicine, which more truly require the assistance of a physician of integrity and skill; than Gonorrhcea and Venereal. I now pro- Gonorrhcea,— Treatment and Cure. 61 ceed to those other circumstances which occasionally occur in Gonorrhoea,—the first of which is,— Excessive pain and heat in making water.— This is nothing more than a higher degree of the first or inflammatory stage of Gonorrhcea which has been already noticed, but which must be subdu- ed before the remedies for stopping the discharge are entered on. The means for reducing inflamma- tion are,—purging, low diet, rest, and the freest use of diluting drinks, for which directions are given in note 6 and 7. You cannot make too free a use of dilutants. The burning pain arises from the saline nature of the urine passing over an inflamed and irritable passage. The urine is loaded with salts---it is like brine; if, therefore, you dilute it with perhaps a gallon or more of water, it is easy to imagine how its stimulating property must be diminished. Sooner or later, by the means above directed, this heat and pain will considerably abate, and then, and not till then, can you safely proceed to lessen the discharge. Swelling of the Foreskin.—The foreskin, called the prepuce, will often swell prodigiously, but this, of itself, is of very little consequence. A soft rag wet with brandy and water, simple water, or any cooling lotion, as in note 4, and wrapped about the part, together with a dose or two of purging pills. is all that is required. The rag should be wetted 62 Gonorrhcea,— Treatment and Cure. often. It is of some advantage too if the penis is kept upright, which can easUy be done by pinning or fastening it to a bandage around the waist. But this swelling sometimes is so great that the fore- skin cannot be pushed back from over the glans or head of the penis. This condition of it is called a phymosis, and, sometimes again, when it is push- ed back it cannot be drawn forward, and this is called a paraphymosis. Now, both these states are of great consequence, particularly the latter. The chief thing to look to in the first (the phymosis) is cleanliness, and here the patent syringe in the little case is of the ut- most use in washing out the humours that collect beneath the foreskin, and which, by becoming, acrid and offensive, increase the malady greatly.— It is necessary therefore to inject some proper fluid under the foreskin several times a day. Any thing that will wash away these humours is better than nothing, so that warm or even cold water may be used ; but the best thing for this purpose is a lotion made of no. 1, of the injection powders—for this is cooling and healing to the part as well as cleansing. The paraphymosis, is of still more consequence; indeed, you should loose no time in endeavoring to reduce it,—that is, to bring the foreskin forward again over the glans, or head of the penis. With this object you proceed in the following way. Take Gonorrhcea,— Treatment and Cure. 63 hold of the glans, which is always very much swelled, with the fingers and thumb, and steadily press it, gently increasing the pressure in order to squeeze back some of the stagnant blood and lessen its size. It is better if you first hold the hand in very cold water. Immediately after thus diminish- ing its size, apply the two thumbs to the glans, and grasping the foreskin with the fingers, steadily push back the glans while you pull the foreskin forward. A little force may be necessary, but you will almost always succeed; if not, the only thing a surgeon could do, would be to cut the skin on each tide, where it is the tightest, and then it will easUy pull over; this might be done with a sharp pen-knife or razor, after this apply a poultice. In both these cases, of course, it would be proper to live low, keep as quiet as you can, and to purge freely. Frequent and very painful erections of the pe- nis.—This is what the French people call Cordce, and a very painful thing it is. I have already pointed out its nature in page 7,—it occurs particularly at night—the penis often being quite crooked at these times. When cordee is disposed to come on, it cannot always be prevented entirely, but it can al- ways be relieved and rendered tolerable. Further a cordee once come on, it is often the last symptom to leave a patient. The best way to prevent a cordee from coming *H Gonorrhcea,— Treatment and Cure. is to prevent inflammation, by rest, purging, and low diet; the best way to relieve it when it has come on, is to take two or three of the anodyne pills in the little case, at bed-time, or those in note 13 be- low. After a few nights, see if you can leave them off, but if the pain come on again, return to them. With a view also of relieving the inflammation of the penis, on which this symptom depends, it is a good thing to emerse it in a basin of warm water for a quarter of an hour on going to bed, and after- wards to wet a soft rag with brandy, or vinegar and water, or common water, and wrap it round the penis. Some contrive to have a bottle of cold wa- ter near the bed, which they hold between their legs whenever it awakens them. Swelling of the glands of the Groin.----This is of less consequence in Gonorrhoea than in Venereal disease;—it is a very rare thing in a Gonorrhcea for these swellings to form into matter and break, as they do in Venereal. Brisk purging with the pills,—as much rest as possible,—and at night a rag wet with brandy and water or vinegar and water laid on them, is all that is required ; under this plan these swellings almost always subside. I have in- Note 13.—Those who have and ten of Opium in twenty not the little case, may imi- pills—of which take two or tate the anodyne pills in the three at bed time. If this following way. Get an cannot be done let thirty or apothecary to make up forty forty drops of Laudanum be grains of camphor—twenty taken in a little water. of the extract of Hyosciamus Gonorrhcea,—lis Treatment and Cure. 65 deed sometimes seen them form matter and break, but it has always been in scrofulous habits, and has been owing to the constitution rather than the Go- norrhoea. In such a case should tumours threat- en to form matter, leeches to it would be proper and desirable. Swelling of the Testicle.—When this complaint happens, it geneially begins about 10 or 14 days from the commencement of the discharge, but it may occur at any time. At first there is an uneasy feeling about the part which you riiight judge to be the situation of the neck of the bladder—just behind the Scrotum (the purse.) Then there is a swelling of the back part of one or of both the testicles, and when the inflammation proceeds into the substance of the testicles, there is great pain and fever. From the moment an inflamed testicle is threatened by these symptoms give up every means for the cure of Gonorrhoea and turn your whole attention to this single circumstance. In the cure of this affection, the first thing to be recommended (when it can be done) is rest, and resting on the bed is preferable to any other. The next, to support the testicles by means of a suspen- sory bandage.—If you have not this at hand, it may easily be contrived.—Make a bag of soft linen large enough to hold the swollen parts, and then sew or pin it to a bandage or pocket-handkerchief round 66 Gonorrhcea,—Its Treatment and Cure. the body. If the testicle is suffered to hang by k& own weight, this alone will prevent its cure and greatly augment the pain.—Next, take 5 or 6 purga- tive pills.—Frequent and repeated purging is a pow- powerful means of relieving this disease, arid this may be followed up either by repeating the pills, or doses of Epsom salts. Lotions also are of great use, and the best of all is the common evaporating spirit Lotion ;—it is made by mixing one part of brandy to two of water, and applied by keeping a soft rag and the suspensory bandage constantly wet- ted with it. Bleeding by leeches is exceedingly useful where the pain and inflammation are great. but many persons are placed in such circumstances as not to admit of their use. There is however another way of taking blood from the part which might be resorted to in very urgent cases, or might be practised at sea, where leeches are not always to be had;—it is as follows.—Stand before a warm fire and pull up the scrotum so as to put the skin on the stretch,—you will then see several veins of a blue color:—Take a lance or very sharp pointed pen-knife and puncture five or six of them ;—then, with a sponge and warm water bathe the part, and you will be able to get more blood than by leeches and with far less trouble and risk of exposure. The bleeding ceases on lying down, if not applying cold water will soon stop it. Sometimes, even under the best possible treatment, great pain and inflam- mation wiU continue and you are under the necessi- Gonorrhcea,—Its Treatment and Cure. 67 ty of taking opiates. Forty or fifty drops of lauda- num may be taken at bed time. The best form however, of opiate medicine is, if it can be procur ed—15 grains of Dovers powder, with two of Calo- mel at bed time. This is as far as I would advise any one to go on his own judgment. In very many cases these means will stop the progress of this symptom, and, indeed, remove it; but, on the other hand, there are some cases in which it will not,— the pain goes on and is attended with fever and perfect inability to go about. In this case I would advise, if possible, to call in the aid of medical as- sistance ; but, in many cases, this is quite impossi- ble,—you may be at sea, or in the country, or where you cannot command this assistance, and therefore I will pursue this subject and describe the best mea- sure to adopt in such a case in note 14. Note 14.—If rest, low diet, purgative medicine, lotions, said perhaps leeches to the part, do not succeed in lessen- ing the pain and inflamma- tion, then a very copious bleeding should be resorted to. Indeed bleeding would be proper in any case, but we do not always have recourse to it, hoping to succeed with the means before mentioned. From one to two pints of blood may be taken from the arm and repeated if not suc- cessful in allaying the pain, swelling, and fever. At the same time, large doses of Tartarized Antimony should betaken. Eight grains may be dissolved in half a pint of water, and an eighth part of this may be taken every second or third hour. This is a ljBge dose, at first it may vomit or purge, but this should be no objection to continuing it, unless the vo- miting should be excessive,— it wilf generally cease after a day or two- There is no medicine which has such power to subdue inflamma- tion, and especially inflam- mation of the Testicle, as Tartarized Antimony, and so important and so painful is this inflammation.that a little inconvenience or nausea and vomiting should not hinder 68 Gleet,—Its Nature. CHAPTER V. On the Nature and Cure of Gleet. A Gleet is almost always the consequence of a badly managed Gonorrhoea. Instead of following up the cure of that disease by the injections which are here so particularly dwelt on, the discharge is suffered to go on from month to month, and the effect of this is to entail a permanent weakness of the parts affected. from its use and benefit. If the pain should be very great, and prevent sleep at night—three or four of the anodyne pills may be taken at bed time,—or twenty grains of Dover's powder with two grains of calomel. If this is not at hand, forty or fifty drops of Laudanum may be substituted. Leeches are always of use—fifte#i or twenty on the part and after- wards cover with a warm poultice. At other times, if it ean be had, ice may be used. Sometimes cold applications will do when warm ones will not; at others warm will an- swer when cold will not. If »ne has been tried without success always try the other. When ice is used let it be powdered and put into a blad- der half full of water, and lay it on the inflamed and swollen testicle. It is astonishing how quickly this will some- times relieve the pain and in- flammation. There is a way of obtaining cold when yon cannot procure ice. Just mix equal parts of Sal ammo- niac, Saltpetre, and Glauber Salts, and put into a blad- der of water, instead of ice : as these dissolve much cold is produced. I have dwelt longer on this subject than on some, as it is a severe complaint. I have found it so in my practice. A sum- mary of the treatment of in- flamed testicle then is as fol- lows. Suspend the testicle,-- rest,—purge,—leech, — and apply cooling lotions. If pain, inflammation,and fever, still run on--Bleeding, Leech- es, Tartarized Antimony, and the application of cold. Gleet,—Its Nature. 69 It is important to understand the nature of this malady, as well as how to cure it, especially as a very serious error respecting its infectious nature, prevails with many. It is a very common thing to hear it said that a Gleet is not infectious; but this is very wrong, and often leads to terrible disasters;— virtuous and unsuspecting women are,unintention- ally involved in this complaint in consequence.—A person who is about to marry, for instance, may not have had Gonorrhcea for six or nine months, or longer; but a slight discharge—so slight indeed that he has scarcely observed it—may have continued all this time. But he does not dream of its infectious nature until the sadest consequences show them- selves. So also, unfortunately, does a similar cause of unhappiness frequently occur in those who have been abroad or from their family for a length of time. Indeed, the consequences of this error are so very serious that it merits any pains and trouble to set the matter in its own true light, and perhaps I cannot do this better than by giving a case or two as related by Sir Astley Cooper. On this subject, then, Sir Astley observes.— u Gonorrhcea, when neglected, sinks into a Gleet, and :< is known by the change of the color of the dis- u charge, and the pain attending the inflammatory " stage ceasing. In this state, is the discharge in- u fectious or not ? I doubt myself whether a Gonor- " rhoea ever loses its power of causing infection as 70 Gleet,—Its Nature. " long as any discharge from the urethra remains, " and I will give you my reasons for this opinion. A " married gentleman went to Lisbon from this coun- " try, [England] and whUst at a distance from home, " departed, as too many do, from the path of virtue, " and went astray. The Portuguese lady with whom " he cohabited, gave him the Clap. He returned to " England, and, after the expiration of five months " and three days after first observing the Gonorrhcea, " he called on me, and asked whether he might re- " turn home with safety to his wife. He said he " had a little discharge, and wished to know, if, after " having had it five months and three days, it were "possible for it to be infectious. I replied—' Cer- " tainly not; you may go home—there is no danger " of your giving it to your wife.' He went home. tc and unfortunately gave his wife a severe Clap. I " attended both the parties afterwards, and was ex- " tremely sorry for what I had done ;—but I thought, " at the time I gave the advice, that a Gleet was not " infectious. But I think differently now,—and be- ' lieve that, after a continuance of several months, " the discharge is infectious." Another instance.—" A gentleman from the north " of England, and who had been recently married, " came to me, and said that he had communicated a " Gonorrhcea to his wife. Shocked at such an oc- " currence, I said, ' How could you think of acting ; i n such a manner V ' Why, sir,' said he,' for four- Gleet,—Its Nature. 71 ''" teen months prior to my marriage, I had a Gonor- '■'• rhoea; I made various attempts to get rid of it, and " had a variety of advice about it, but a yellow dis- " charge always continued. I was told by every " body that it was not infectious,—and not until after " such repeated assurances did I get married; the ': consequence, however, is, that my wife has a severe ': pain in making water, and a copious discharge.' I " visited her, and found her in this state; she was '"'• some time under treatment before she quite re- " covered. From what I have seen, I do hold that :' a medical man is not warranted in saying that a " discharge of a gleety kind is not infectious." On these two cases thus faithfully related, then, every person will be able to form his own opinion on the infectious nature of a Gleet; I think they are sufficient to make every reflecting conscientious per- son take care how he gives advice in such a case, particularly if his patient is a married man.—Indeed, it is from this error, or from a total indifference as to its consequence, that we have so many cases of Gonorrhoea,—they are twenty to one, compared with cases of VenereaL In fact, the common women of the town pay no attention to a Gleet. After the first or inflammatory symptoms of a Gonorrhoea have subsided, they mix with society as though nothing ailed them. In the patients of the Hospital called the " Lock," in London, for instance, nothing is more common than to see the Venereal and the Go- 72 Gleet,—Its Nature. norrhcea in the same female; but it is the Venereal which brings them there. As to the Gonorrhcea, or Gleet, they will tell you they have had that a long time, and thought nothing of it, but having got the Venereal, in the form of chancres, they became alarmed, and anxious to be cured. So also, when the Venereal is cured, they seldom stop in the Hos- pital for the cure of the Gonorrhcea, or Gleet, but go out again promiscuously in the town and spread the Gonorrhoea in every quarter. I do not however, after all, say, that every Gleet is infectious, but, they are so generally, and there is no mark whatever by which it can be said that this is infectious and that is not,—this can only be known by its consequences. How serious therefore to say to any one, especially to a married man, or one about to marry, that a Gleet is not infectious. But it is incumbent also to state, that there is a discharge from the urethra, in some measure resembling a Gleet, which is not infectious. A discharge of this harmless kind may proceed from two causes which may be easily understood. In the first place, it may proceed from a little abscess which occasionally forms # m the urinary passage, and breaks; and the other is, a discharge proceeding from a Stricture. Now, the nature of these two causes of discharge must be understood, and then a suspicious gleety disorder wiU be easily detected and distinguished from either of these. Gleet,—Its Nature. 73 First—With regard to the discharge from the little abscesses above-mentioned, it should be known, that, in the whole length of the urinary passage are situ- ated, here and there, little sacks for the purpose of secreting a lubricating fluid; these are called,—la- cuna. After a Gonorrhoea, these little lacunas are sometimes affected with common inflammation, which forms into abscesses, and when these burst and their contents are discharged, the running ceases. Now, the circumstance by which these abscesses may be distinguished from a Gleet, is this ;—the dis- charge from these lacunae stops entirely for a week or two, and then, when another breaks, it comes on again, suddenly, and again ceases as before; but the discharge from an infectious Gleet never stops;—it may increase, from excesses or irregularities of any kind; and it may decrease, so as to become very trifling,—but it never ceases altogether. This, there- fore, affords a good rule of judging between Gleet and a discharge from these abscesses in the urinary passage. And next,—With respect to the discharge arising from Stricture, this will be easily detected by con- sidering the symptoms proper to Stricture; and, should any doubt exist, this may easily be removed by the use of a Bougie. For the symptoms proper to Stricture, and for the use of the Bougie, the reader is referred to the next chapter, which treats expressly on those subjects. 74 Gleet,—Its Treatment and Cure. The Treatment and Cure.—A Gleet is a very troublesome disease to manage. If there were no other reason, I might safely infer this from the num- bers who come to me with this complaint, having had it on them, more or less, for a length of time. These patients generally state they have tried a great variety of means, and are quite disheartened. I can- not always learn particularly what these means have been, but two important things I do know; the first is, that whatever they have been, they have always failed; and the next, whatever has been the state and condition of their case, the means I am now about to mention have always succeeded. I think it right to premise these remarks because it may be thought the plan I recommend is very troublesome ; it may be so; but then, I would repeat, this plan succeeds when every other fails,—and I am quite sure no better can be availed of. In the first place then, begin with the Black Pill;— or, if prefered, either of the other remedies mentioned in chapter III. At the same time also begin with the Injection. Both the internal medicine and the Injection are to be used exactly as for Gonorrhcea. To save unnecessary repetition therefore, you are re- ferred to chapter IV, on the treatment of Gonorrhcea. But the most troublesome part of the treatment I recommend, is the use of the Bougie. Many per- sons, I know, may not be able to procure them, and Gleet,—Its Treatment and Cure. 75 ^ others may not like to venture on their use. It will be satisfactory therefore for such to hear that I do not consider the Bougie absolutely necessary, but only state, that, cases which have been very tedious and obstinate under every other-means, have got well very quickly when the use of the Bougie was added to them.—Instructions for the use of the Bou- gie I shall give in the next chapter, on Stricture; here I would observe only, that it is not required to begin with the small size, as in Stricture, but to select a medium or full sized Bougie, and pass it in the manner there directed every day; or, if it give un- easiness, (which is not usual) every other day, as long as the disease continues. It often happens there is a little increase of discharge on first using it, but this soon goes off. The stretching of the urinary passage by the bougie, and the stimulus thus afford- ed, expedites the cure of Gleet exceedingly. Those therefore who have been long tormented with this complaint should not think the trouble of the Bougie too much to get rid of it. When, however, it cannot be procured, or is exceedingly disagreeable, it may be dispensed with. There is another medicine sometimes taken for the cure of Gleet—the Cantharides, or Spanish Fly. I have sometimes given it, by way of change, in cases which have proved unusuaUy obstinate—see note 15. Note 15.—The best way to form of pills, which should take this medicine is in the contain one quarter or one 76 Gleet,—Its Treaiment and Cure. The following then is a summary of what has now been said on Gleet. It is a dischaige of a bluish or yellowish humor from the urinary passage—some- times clear—sometimes opaque;—there is no pain attending;—it is almost always the consequence of a badly treated Gonorrhoea. Its treatment is like that of Gonorrhcea, but the use of the Bougie is a valuable addition;—this however is not essential to its cure—it expedites it only. Another addition to the treatment is, the internal use of Cantharides, or Spanish Fly. half of a grain of the powder in each; one of these pills should be taken night and morning, and, after a little while, three times a day. It is better to make the cantha- ridas into pills with one or either of the thicker kinds of turpentine; the best of these is that called Chio turpentine. of which five grains should be allowed to each pill; if this size is two large, it may be made into two instead of one. It should be continued a considerable time to do any good. If it produce heat and frequency of making water, leave it off for a day or two, and take flaxseed tea, or bar- ley water. Stricture,—Its Symptoms. 77 CHAPTER VI. On Stricture,—its Symptoms, Nature, Consequen- ces, and Cure. When a person comes to me with a Gonorrhcea that has continued an unusual length of time,—up- wards of two months, for instance, I consider this to be a sufficient reason to suspect he may possibly have a Stricture, and that it is my duty to ascertain for fact whether it be so or not. Now, the early symptoms of Stricture are a scattering of the urine in making water, or a splitting of the stream, or a smaller stream of urine than formerly. If these or any one of them, is acknowledged, my suspicion is increased. But if he says he has not noticed these, I am stiU not certain he has no Stricture, for these, sometimes, particularly the smallness of the stream of urine, will come on so gradually that he may not have noticed it. Until the stream becomes remark- ably diminished, a patient is very apt to believe and say it flows as usual. I have had patients tell me this, when, on examining the passage, I have found a considerable Stricture, and then, reflecting on their former way of making water, they have acknowledged that the stream had become diminished. But, if still in doubt, there is another question I often put;—it is if they remember, when they have done making 78 Stricture,—Its Symptoms. water and have buttoned up their clothes, whether a single drop or two of urine ever passes afterwards, so as to wet the shirt a little. This is the very first of all the symptoms of a Stricture, and the answer to this question has frequently determined me, and correctly too, upon this subject. If, however, to all these questions a negative is given, so that he has neither a scattering of the urine, nor a diminished stream, nor a drop or two which passes after he thinks he has finished making water, then he has no Stricture, and you may boldly proceed to cure the disease on the principle of common Gleet. On the other hand, if be states he has these symp- toms, or any one of them, this will afford sufficient reason to suspect a Stricture, and no faithful physi- cian will proceed one step further without ascertain- ing for fact whether it be so or not. This can be done only by passing a bougie,—a safe and simple means in proper hands, but which will be mentioned more particularly presently. Nothing can better serve to distinguish the dis- engenuous, advertizing, boasting knave, from the good physician, than the difference of their conduct in the case of Stricture. The former Avill never trouble- himself or you with the sound of Stricture, but will sell you drops, or pills, or some such thin°- as long as you will take it, and in the end leave you in mental misery and incurable disease; the latter Stricture,—Its Symptoms. 79 will not rest until he has ascertained the case,—he will then explain its nature, show the utter inutility of medicine alone, and conduct you, by a rational, safe, and easy course of treatment, to a perfect cure. None but those who see it daily can form the least idea of the misery escaped by falling into the hands of such a man. But, so far I have spoken of Stricture only in its early stage,—at the time when its symptoms are so few and give so little inconvenience as to allow its existence to be overlooked ; in its advanced stage however, the symptoms are very numerous, and some of them most deeply interesting. The interesting nature of these symptoms arises from their remote- ness from the seat of the disease itself, so that when they present themselves, they are never once sus- pected to arise from Stricture, and, consequently, never get relieved. Many serious diseases, which, v from their having proved unyielding under a variety of modes of treatment, have been thought incurable, and have been so because they have arisen from Stric- ^ lure, which was never thought of.—As an instance;— a few months ago a captain of a merchant vessel from Havana, came to mc with a recent Gonorrhoea; but who, in a little while, I perceived had got a Stricture also, from a former Gonorrhoea. Of course I soon attacked the Stricture, but, as the cure of this proceeded, he told me with the greatest pleasure and surprise that his eyes were better. Now this was SO Stricture,—Its Symptoms. the first time he had spoken of his eyes, though I had noticed they were very red and irritable. He then told me that his eyes had been bad for years—that he almost always wore a shade, and that they were frequently so bad at sea that he could not open them at all in common day-light. This, therefore, was a case of Opthalmia from Stricture, but which had given him so little pain or inconvenience, until a fresh attack of Gonorrhoea occurred, that a Stricture was never once suspected. By the time the Stricture was cured, the eyes got well entirely, and I believe will never trouble him again. But this is nothing new in the treatment of Stricture; nothing is so common as to see complaints which had resisted every former mode of cure, particularly diseases of a dyspeptic nature, entirely disappear on the cure of Stricture. The symptoms denoting confirmed and longer standing cases, therefore,—indeed every thing relating to this subject, is deeply interesting. As I have said before, a contracted stream of urine, more or less, always attends a Stricture, but this creeps on so gradually, and with so little disturbance, that it often quite escapes the notice of the patient. But, as the narrowness of the strictured part increases however, this alteration or contraction draws atten- tion, for it becomes very small, or divides into two, or sprinkles on the ground; and, in very bad cases it passes only drop by drop, and that not without much straining. Sometimes it is necessary to make Stricture,—Its Symptoms. 81 a great effort at the beginning, and afterwards it will flow in a full enough stream; at other times the desire comes on so quickly that you cannot retain the urine for a moment. This is when the bladder par- ticipates in the disease. The bladder is always more or less disposed to this participation, so that many patients are obliged to get up in the night, or oftener than they were accustomed to do. In many cases of Stricture also, there is a dis- charge from the urinary passage, but this does not happen in every case. This discharge may.be only a little more of that mucus which is natural to the part, or it may be real pus or matter. Whatever it is, however, it varies from many circumstances of excitement. When the discharge is considerable, it is often taken for a Gonorrhcea, especially as this may be attended with burning pain in making water, and Cordee, all of which is very apt to follow the excitement of sexual intercourse. There are also various sensations and other symp- toms which may or may not occur. These are ex- ceedingly well enumerated by Mr. Bingham, of London,—a very sensible writer on Stricture,—from whose work I will transcribe the most important,— leaving out however all technical words. Nothing, correctly detailed, can be uninteresting to one afflict- ed with Stricture. 6 32 Stricture,—Its Symptoms. Mr. Bingham observes—" Various kinds of sen- " sations also, are produced in different degrees, by " Stricture in the urinary passage: as, an itching of " the penis or the parts about, and a fluttering or " pulsating sensation in some part of the passage; " numbness in the thighs is another symptom; as " are also a smarting or burning pain in the head of " the penis, and darting pains shooting to and fro " from the fundament to this part, or up to the back " and loins ; pain in the hip, down the thighs and on " the inside of the knees, frequently occurs from " Strictures in the urinary passage, and pain has " also been known in the sole of the foot from the "same cause." Again he observes—" Sexual intercourse is apt to "' aggravate the symptoms of Stricture whatever "they are. Sometimes this act is attended with "pain and inability to emit the semenal fluid; at " other times only part of it passes, and the remainder " steals away when the erection has ceased. Reten- " tion of urine has many times been brought on by "sexual connexion, in patients troubled with Stric- " ture." "The penis is variously affected by Stricture. " Sometimes the erections are excessively frequent "and troublesome, and these may or may not be " accompanied with semenal emissions during sleep; Stricture,—Its Symptoms. 83 " at other times the erections are weak and ineffi- " cient, and, occasionally, altogether wanting." " Sometimes swelling of one or more of the glands " in the groin, and enlargement of the testicle, indi- " cates the existence of Stricture in the urinary pas- " sage : and another symptom is, hardness to be felt " externally in the- situation of the Stricture. In- " fiammation and a gathering in that part of the " middle between the anus and the testicles are also " symptoms of the disease." " " It has been stated upon high authority, that " strictured patients cannot comfortably cross their " legs; but whenever I have had an opportunity to " notice this, there has been, beside the Stricture, " disease of the prostate gland," (a hardish body situ- ated at the entrance of the bladder, just where the urinary passage begins, and which is exceedingly liable to enlargement in elderly people) " or inflam- " mation about this part." The sympathy between the organs of generation and those of digestion is very great, giving rise to many remote affections of a dyspeptic nature. In other words, a stricture in the urethra is capable of disturbing the stomach, and through this medium, of inducing other and remote complaints, all of which therefore are correctly placed among the symptoms of stricture. These complaints are chiefly of a nervous 84 Stricture—Its Symptoms. character, as head-ache, low spirits, diminution of wonted clearness and energy of mind, and other hy- pochondriac feelings ; and so evidently are these the effect of stricture, that they cease as its cure pro- ceeds, while they resist every measure short of this. A knowledge of this fact is of great importance too, in the treatment of strictures, for, as a stricture in the urethra has so much influence on the stomach, in like manner the stomach influences the stricture. Now, we can at all times prescribe for these distur- bances, and hence the cure of stricture is so much expedited by attending to the stomach throughout its treatment. My own practice verifies this state- ment daily. Sores about the head of the penis and foreskin. much resembling Venereal and frequently mistaken for it, are also among the symptoms of stricture.— The late Mr. Abernethy in his work on Syphilis. has admirably shown this fact. To what he has stated I can also add my testimony, for instances have occured to me in which these sores have prov- ed unyielding under many surgeons and different modes of treatment, but which have got well speed- ily on treating them accordingly. Sores and other affections of the throat are some- times symptoms of stricture,—they occur on the same principle, viz :—the sympathy existing be- tween the organs of generation and the throat—so Stricture—Its Symptoms. 85 that disorder in one will produce disorder in the oth- er. Many curious.facts might be stated on this subject, but as I observed, being rather curious than of practical importance, I will state them in a note (16.) The last symptom I will mention, is a hardness and diseased condition of the testicle from stricture.— This indeed may arise from other things than stric- ture, but when it thus arises, and this I often find to be the case, it never can be cured but by the re- moval of the stricture. A summary then on the symptoms of stricture may be stated thus;—that, in the early stage, or when its progress has been slow or almost stationary for a length of time, the symptoms of it chiefly relate to the size of the stream of urine, or to the manner in which it passes; this however only affords a ground of suspicion of a stricture.—But, in more confirm Note 16.—The sympathies between the organs of gene- ration and the throat in both sexes are very striking. Not only is the beard upon the chin prevented if the testicles are removed before the age of puberty—but also the de- velopment of the throat is hindered, so that the voice fails to attain the deep and tenor tone of men. It i9 a curious fact, that, when the corresponding organ of the female is removed (as in the ovaria in spaded animals) the voice becomes deep and rough in women, and hair shoots out upon the lips and chin. Young women who have beards are generally less prolific than those who have none. Bingham mentions a case which came under his own knowledge, of a young lady who had a beard, but lost it after her marriage..— All this shows the intimate connection which exists be- tween these distant organs, and accounts for many mor- bid actions occuring in the throat simply from sympa- thizing with a stricture. 86 Stricture—Its Symptoms'. ed, or longer standing cases, the symptoms are much more numerous and important, as have been descri- bed ; still these alone do not prove the existence of it, for all these symptoms may arise from other cau- ses. It is therefore needful to have some other means of coming to the point, and this is amply furnished in the Bougie.—A bougie is a soft smooth instru- ment, which, if no stricture or disorder in the pas- sage hinder, can be passed without pain or incon- venience through the urinary passage to the bladder— —but which, if there be a stricture, stops and proves the fact. The Nature of Stricture.—This is easily explain- ed. The urinary passage is composed of a dense skin, having an elastic power, so that when the urine is forced into it by the bladder it enlarges to transmit the stream. Gonorrhoea, essentially, is a state of inflammation, and the effect of inflammation, when long continued, is to alter the natural condition of the part in which it may be seated. Now, in the present instance, it alters and destroys the elastic power with which the urinary passage is endowed, so that it no longer yields to the flow of urine as it ought to do, and hence the stream is lessened and its force diminished. Also, there are certain portions of the urinary pas- sage, it is well known, more liable to inflammation Stricture,—Its Nature. 87 than others, and, accordingly, Stricture is most fre- quently found to be seated in these very portions. Again, long-continued inflammation is known to thicken any partf in which it may be seated, and this is the case in Stricture. Beside the loss of its elas- tic yielding power, therefore, the passage also be- comes thick and callous; so hard and thickened u an old bad Stricture as to threaten an aclual oblitera- tion of the passage, for the urine passes in the smallest stream, and sometimes only drop by drop. On the nature of a Stricture also, it should further be observed, there is no natural cure for it. When a Stricture once begins it is sure to go on increasing, either rapidly or slowly. Fortunately, however, we have the means of curing it by art, as will presently be described.—Neither is it curable by medicine; all the medicine in the world, alone, would never cure a Stricture. On the nature of Stricture then, it may be said, it consists, at first, in a loss of the dilating power of the urinary passage, by which the stream is lessened; and next, in a thickening of the parts, by which the stream is constantly diminishing; and, that it is curable by art. The Consequences of a Stricture.—These are truly lamentable,—not only being distressing to en- 88 Stricture,—/** Consequences. dure, but, some of them totally incurable,—admitting only of relief. I speak however now of old bad cases such as have been suffered to run on for years, or badly treated. Beside those sympathetic disorders then which were noticed in speaking of the symptoms of a Stricture, there are consequences which are more immediately connected with it, and these I next propose to state. One of the first of these consequences is, the effect which straining has upon the bladder. The more resistance the Stricture offers to the flow of urine, of course the more exertion must the bladder make. This leads to a thickening of its coats and to other conditions of it which make it irritable and incapable of retaining but a very little urine, so that the calls are frequent and pressing,—disturbing sleep and rest. From the same cause also, the kidnies are very apt to be diseased. The next effect of so much straining is produced upon the passage itself, just behind the strictured part. The force of the urine, as may easily be im- agined, dilates the canal and forms a pouch or bag in which a portion of the urine lodges. But this, which always happens more or less, may lead to la- mentable consequences. In the first place it may render the passing of the bougie impossible ; for, when the pouch is large^ the orifice leading out of Stricture—Its Consequences. 89 it may not correspond exactly with that leading in- to it, so that the bougie may easily pass in, but not pass out or through it. And, in the next, the urine lodging here is very apt to irritate and produce dis- ease. Disease arising from this cause is of the most distressing and permanent kind ; matter forms in the subjacent structures and makes its way out, both by opening into the passage, and also by open- ing externally, ulcerating through the parts between the thighs. But the worst is, the passage it thus makes will not heal. It is difficult and sometimes quite impossible to prevent the urine passing through it. This is whatis called a sinus, or fistula in peri n&o. I scarcely know a more disagreeable and inconven- ient thing than a sinus in these parts,—the person is obliged, to squat down in making water to do it comfortably. But to form a true and clear concep- tion of this malady (and every one should do so, in order to avoid that class of people who produce it) it is necessary to see it in a plate, and with this view I have selected the one on the following page from one of the best and latest authors on the sub- ject, and from this it will be correctly judged how serious a thing it is to neglect a Stricture. Indeed, so true is this that a very eminent writer on this subject,—Sir Everard Home,—Surgeon to the late King of England, in his third volume, has a chapter upon,— Diseases of an incurable nature, the con- sequence of long-continued Stricture, before the proper means of removing it had been adopted. 90 Stricture,—Its Consequences. 2- o* 2. ^ c^ ° " J"* I: * = 5" " | ffl P » ."3 W O O M J> Ir^^I I ^ | h h | ^^>h 0 b oi^»»r»£0^t'tlinS G BJ r» to — ■ oa-j?« means,—if not, desist, and give an opiate, &c, as before directed. In some hours afterwards perhaps you may pass it easily. But there is another state of things for which the bougie is a remedy, beside a Stricture, and that is, a simple state of tenderness (without a Stricture) in some point or other of the passage. Being led to examine the passage from symptoms warranting the suspicion of a Stricture, it is found that the bougie passes perfectly well, so far as obstruction is con- 102 Stricture,—Its Cure. cerned, but, that in passing some certain point a great degree of pain is felt. This disorder is differ- ent from a Stricture, inasmuch as it consists merely in a morbid or increased degree of sensibility, but it is to be treated exactly as though it were a Stricture. Pass the bougie, a medium, or above a medium size, every day, or every other day, as the degree of irri- tation wiU admit, and keep the bowels and digestive organs in a regulated and healthy state. The effect of this treatment, very generally, is to lessen and ultimately remove this morbid sensibility. If there- fore, on every time of passing it, you find the pain and tenderness becomes less and less, you may de- pend upon a perfect cure, as well as the cessation of every symptom which originated from it. Thus have I finished the subject of dilatable Stricture,—its symptoms, nature, consequences, and cure. It is gratifying to have been able to point out ari easy and practical remedy for so formidable a dis- ease. But, this remedy has often been doubted by patients. They have said,—is it possible that an operation so simple can cure a disease so incurable and dangerous under any other means?—The best answer to this, it might be replied, is the daily occur- rence of the fact; but, as some may not have had an opportunity of witnessing an instance of it, and as the intelligent and discerning mind of others may require some explanation of the power by which it does so, I wiU endeavor to give this explanation iq Stricture,—Its Cure. 10 a note (17)—repeating however;—there is no other way of curing Stricture. With regard to the confirmed or callous Stricture, I will not go into the minutiae of its treatment, be- cause I do not consider that the cure of this should ever be undertaken by the patient. The object aimed at, however, is to promote absorption of the callous body, and for this purpose metalic bougies are more useful, and these should be continued in the part for Note 17.—Every part and structure of the body is en- dowed with its own peculiar power of action; also, every part is. endowed with a re- storing power, the activity of which is aroused by every deviation from the natural and healthy condition of a part. This is no fiction. In- deed every restoration from disease to health is an illus- tration as well as a proof of such a principle. Numerous as are the laws which regu- late and maintain the healthy actions of the body, these are not more numerous and im- portant than those which in- fluence and control its mor- bid actions. A Stricture is, essentially, a morbid action— a deviation from the healthy and natural condition of a part;—it has lost its natural powerof elasticity, and if that morbid action which destroy- ed this elasticity could be re- moved, the principle 1 allude to would instantly restore that power. Now, the.Bougie does this. The pressure and excitement of the bougie, upon this deli- cate structure, breaks up and destroys this morbid action, and the healthy one immedi- ately succeeds—the natural elasticity of the passage is restored. On the same principle also are the confirmed and callous strictures cured. Every part of the body is endowed with the principle of absorption. The bougie, in this case, not only destroys the morbid ac- tion essential to the Stricture, but powerfully excites the ac- tion of the absorbing vessels, which is the means of remo- ving that callosity. Indeed the cure of Stricture is affect- ed by the bougie on the same general principle on which every other disease is cured,— it interrupts or destroys a morbid action, when a healthy one succeeds. 104 Stricture,—Its Cure. some hours at the time. The caustic bougie is alto- gether unfit for private use, and is only required id very peculiar circumstances, when it is a valuable means. Gonorrhcea,—In the Eyes. 105 CHAPTER VII. Gonorrhoea in the Eyes, and Gonorrhoea! Rheu- matism. This subject is introduced, not for the purpose of inducing a patient to undertake the cure of these complaints himself, but of apprizing him of their real nature and dangerous tendency, particularly the former, and urging him to lose no time in securing that surgical and prompt advice they need. Fortu- nately, these complaints are not of every day occur- rence. Now and then, however, a person who is under treatment for a Gonorrhcea will be suddenly seized with a most severe Opthalmia. This com- plaint runs on with great rapidity, and, if not speedily arrested, it accomplishes the total loss of sight. It begins with great severity of pain and a copious dis- charge of matter. In such a case there is not a mo- ment to be lost—the advice of a surgeon should be sought. But, as it is possible, and, especiaUy if the physician or surgeon have practised principaUy.in the country, that he may not have seen many cases of this kind; and also, for the benefit of those who may be at sea, and cannot obtain the advice and assistance of a surgeon; or, again, for those who may be obliged to wait some time for his arrival, I will give, in the 106 Gonorrhcea,—In the Eyes. form of a note below (18), an outline of the treatment which is recommended by the most experienced and competent men in Europe. Note 18.—In Mackenzie's Practical Treatment of the diseases of the Eye, he directs the following for this kind of opthalmia.—"Abstinence from all stimulants; blood- letting, both general and lo- cal; and the exhibition of purgatives, or emetic-purga- tives, and diaphoretics, are to be. had resource to in the early stage " The discharge is to be frequently and care- fully removed by injecting under the eyelidy, a lotion made with a grain of the mu- riate of Mercury to an ounce or more of water ; the globe of the eye is to be touchtd once or twice a day with a solution of Lunar Caustic— (four grains to an ounce of water; or, six grains of blue Vitriol to an ounce of water. These are to be used with a camel-hair pencil.) Also, the lids are to be kept from ad hering by anointing the edges of them with the red precipi- tate Ointment. "Counter- irritation ought to be employ- ed from the very first, by means of mustard poultices arid blisters to the nape of the neck, between the shoulders, or behind the ears." "If the pain of the eye is pulsative - or the parts around it are affected with pain coming on at night—Calomel and Opi- um should be given, so as to affect the mouth. Warm fer- mentations, the vapor of lau- danum, opiate friction of the head, and the like, will seem to moderate the pain; but our chief reliance must be placed on depletion, counter-irrita- tion, scarification, and smart- ing applications to the globe of the eye itself for removing the disease. Snipping out a portion of the chemosed membrane (the outer mem- brane of the eye, whose ves- sels are go i gedwith blood) so as to procure a considerable flow of blood, is highly ser- viceable." " Bleeding alone must not be depended on." "This inflammation," (says Mr. Barcet, another eminent and practical man) in the few instances that have come un- der my observation, is of the most violent and intractable description, and hasproduced the total aestruction of the organ of vision, in the space of two or three days, notwith- standing the most vigorous employment of general and topical bleeding, and other antiphlogistic means." To the truth of all this I can attest, upon the ground of my own observation and ex- perience, and I judge it there- fore exceedingly desirable that persons should be aware of the dangerous nature and rapidity of this complaint. that they may not be induced Gonorrhcea,—In the Eyes. 107 With respect to the manner in which the eyes become affected with Gonorrhoea, there has been a difference of opinion. Three explanations have been given of it. First, that it was owing to carelessness, such as inadvertently rubbing the eye with the fin- gers after handling the penis under the discharge of Gonorrhoea; next, that it was owing to the Gonor- rhcea affecting the constitution, when, like Rheuma- tism, it may change its seat from place to place; and thirdly, that it was the consequence of stopping the discharge of Gonorrhcea too suddenly. Respecting the two latter explanations, these cer- tainly are possible but very doubtful causes. With regard to the former, that is, innoculating the eyes by applying Gonorrhceal matter to them, this, beyond a doubt, has been known to be a cause. Formerly I was not so well aware of these facts, but I find they stand upon unquestionable authority, and in order that others may judge correctly and be careful on this point, I will relate an instance or two in a note (19). to trifle away the only chance to me from the country with of cure, for it is on the prompt violent Opthalmia. This pa- and decisive treatment in the tieht having Gonorrhoea, early stage alone that the in- while engaged in removing valuable sense of sight de- the discharge from the urina- pends. ry canal, a drop of the Gonor- rhceal fluid was by mischance Note 19.—Mackenzie, on thrown fairly in upon his left diseases of the Eye, page 344, eye, and excited the severe states—"A patient was bro't puro mucous opthalmia un> 108 Gonorrhoea,—In the Eyes. With respect to the question whether or no there are such diseases as Opthalmia from too suddenly stopping the discharge in Gonorrhoea; and Opthalmia arising from the constitution embued with Gonor- rhoeal disease, it is not necessary here to determine; many persons think there are, and I have no proof to offer that it is not so; moreover, the cases we occa- sionally meet with here and there in the various periodicals would seem to corroborate such opinion. As I have already said however, if there really be der which he was laboring. The Gonorrhoea still contin- ued when I saw him. The in- flammation of the eye subsi- ded under appropriate means, the eye cleared to a degree far beyond my expectations, and a c nsiderable share of vision was preserved." Mr. Allan relates the fol- lowing remarkable case. "A gentleman, aged 17 years, had had Gonorrhoea a few days, when violent inflammation of the eye, attended with a dischargesimdar to that from the urinary canal burst forth. The gonorrheal running from the penis continuing unaba- ted at the same time. In a few days his brother, aged 14—who never had had vene- real disease in any way but who slept in the same room, was attacked with a similar opthalmia in both eyes. In addition te my own attend- ance, Drs. Munn and Mr. Is Bell, of Edinburgh, were call- ed in, and notwithstanding every means that could be devised, the elder brother lost the sight of both his eyes, and the younger brother of one. No doubt the younger used the same towel, or wash-hand bason, or the like." Again, the very eminent and practical Astruc relates a case exceedingly in point. "A young man nad been in the habit every morning of bathing his eyes with his urine while it was yet warm, in order to strengthen his sight. Although he had con- tracted a Gonorrhoea, he did not abstain from this custom, apprehending no harm from it; but the urine partaking of the infectious matter, quickly communicated the same dis- ease to the mucous mem- brane which covers the eye and eyelids (the conjunctiva). The consequence was a se- vere opthalmia.attended with an acrid and involuntary dis- charge of tears and purulent matter, but which yielded to the same remedies which re- moved the Gonorrhcea," Gonorrhcea,—In the Eyes. 109 such cases they are very rare, and I have no doubt that many of those cases of Opthalmia, as well as Rheumatism, which are there related, have been diseases which happened to occur at a time when the patient was laboring under Gonorrhcea, and had really no other connexion than their accidentally occurring at the same time. But, as I have said, as some per- sons think otherwise I will give in the following note 20, (principally for the perusal of medical men) the peculiar treatment which such persons have adapted who have thus thought. Note 20. — Treatment of those cases of Opthalmia which are supposed to arise from too suddenly stopping the dis- charge.—Of course this kind of Opthalmia includes only that in which the discharge is stopped. On this subject Mr. Makenzie (page 376) ob~ serves—"The only point in which the treatment of this opthalmia differs from the former, is in the attempt, so much recommended by some authors, to restore the sup- pressed discharge of the ure- thra. This is to be done by introducing a bougie into the urethra, covered with some of the purulent discharge from the eye, or with Gonorrheal matter from another subject. Even the simple introduction of the bougie may perhaps produce the effect so much desired; for any stimulus ap- plied to the lining membrane c»f the urethra, provided it be of sufficient activity to deter- mine an irritation and a secre- tion of mucus, may produce a running similar to Gonor- lhea. If this plan is adopted the bougie must be retained in the urethra for several hours at the time, till the ef- fect is produced." With regard to the treatment of those cases of Opthalmia which are supposed to arise from the constitution being embued with Gonorrhaal dis- ease,—Scarcely any thine is recommended which diners from the treatment of a simi- lar state of opthalmia from cold or any common cause. . The discharge from the uri- nary passage may be present, or may not; and, it is worthy of remark, that when it has come on, not having been ooserved when the opthalmia began, in many cases, the occurrence of discharge from the urethra has made no dif- 110 Gonorrhcea,—In the Eyes. I fear I shall incur 1 this note to so great a ferencein the symptoms of the opthalmia. Notwithstanding this however, a celebrated writer upon Gonorrhoea— Swediaur—advises "theuse of the Bougie for a couple of hours," with the intention of bringing on discharge. This kind of opthalmia, too, is less severe than theformer, or that arising from matter applied immediately to the eye;—it is of a more chronic nature, and begins in the eye- lids in the form of little ulcers from which a yellowish mat- ter exudes; while in the for- mer kind, the whole surface of the globe of the eye and inner surface of the lids are affected with redness and swelling,—the matter dis- charged also is profuse and frequently acrid and excoria- ting to the outer lid and sur- rounding skin. Abernethy, in his Surgical Lectures, calls it irritable Opthalmia, and ascribes it to an irritable state of the con- stitution in which the bowels and digestive organs deeply participate. When this state of the constitution is brought on, either by the Gonorrhea, or the means adapted to cure it, he states that either this Opthalmia, or Rheumatism, may occur; or that they may both occur, alternating with each other, even alternating with the disease of the ure- thra, and that the proper way for having carried out 1, but the consequence of treating it, beside soothing applications to the eye, is to give five grains of blue pill every night and a dose of cas- tor oil in the morning, keep- ing the patient on a strict spare diet. In support of this opinion he gives the following case. A gentleman who had been anxiously endeavoring to get appointed commander of a frigate while in the country, at length received instruction from the admiralty to take command of a frigate then lying at Falmouth. He lost no time in placing himself in the mail coach for London. Just before he left Edinburgh he had caught a Gonorrhea. In January his eyes became inflamed; and when he reach- ed i ondon, he had a violent Opthalmia, with purulent dis- charge. He was in a dread- ful state both of body and mind, could not bear the light, and had great pain in his eyes. In this state he consulted Mr Abernethy. He stated also that when the discharge from the urethra stopped, the eyes became bnd, and when the eyes got well the Cionor- rhea returned. In this state Mr. Abernethy directed him to keep quiet in a darkened room, to wash his eyes fre- quently in the course of the day with tepid poppy water, to take five grains of blue pill every night, and a dose of Gonorrhcea,—Rheumatic. Ill of delay or any misconce] malady, especially that of castor oil next morning, and to live strictly low. " During the first six days he mended very slowlv, and not consi- derably. But on the seventh day, when Mr. A. called, he found the patient sitting up in his room, the window un- covered, and his eyes almost well Mr. A. expressed his surprise, and asked how this change had so suddenly hap- pened, to which he answered, that he had had a number of very copious stools in the night,and that his complaints had left him. It seemed to be a sort of critical secretion from the liver and the whole of the alimentary canal, fol- lowed by an almost immedi- ate removal of the irritable inflammation of the eye " Mr. Abernethy also takes occasion to warn persons against mistaking this Op- thalmia arising from an irri- table state of the constitution and digestive organs, for that following innoculation, or the immediate application of Go- norrheal matter to the eye, foT the means recommended for the first would add to the irritability and debility of the constitution, and increase the disorder. His words are, that, "if the surgeon is frightened at. this irritable opthalmia, supposing it to be one of the dreadful cases in which the eye is clapped, and proceeds to bleed and purge the patient jtion of the nature of this innoculating the eye with severely, he will only make the matter worse. Moderate bleeding," he says, "maybe useful, but the chief object is to attend to the patient's health. No means are so likely to be useful as setting the digestive organs to rights, and sending the patients to the country. On the treatment of Rheu- matism, from the same sup- posed Gonorrheal taint of the Constitution, but little can be recommended in addition to what is approved in Rheu- matism from other causes. The history of a case of this kind will best convey what is meant by this disease. Major---, aged 25, con- tracted Gonorrhea. In a fort- night he was seized with swelling of the testicle. When this abated pain and swelling of the right knee began; on travelling in an open carriage on the second day the other kneer foot, and joint of the great toe swelled. The pain was excrutiating He then came under the care of Sir Henry Halford, (the king's physician) but no treatment seemed to possess any power in removing the complaint. Now, in addition, his right eye was suddenly attacked by a very violent inflamma- tion which threatened de- struction to the organ. He I hen gave up medicine and 112 Gonorrhoea,—Rheumatic. Gonorrhoeal matter, is so dreadful that I cannot pos- sibly omit it. It need not however incommode the went into the country for the restoration of his health, and after being there for about three weeks, the Gonorrhea again increased without any abatement of the other symp- toms. The joints so stiff and swollen he could hardly crawl about Warm bath and a residence by sea were recom- mended. From the former he experienced little apparent benefit, but after a tedious convalescence of two years he found himself able to join his regiment in Spain.—He recovered the use of his limbs and had no return of his com- plaint though exposed to many hardships in the cam- paign of 1812, &c. bscurer forms of Venereal disease, should never undertake their management themselves, but, if possible, should consult the most experienced surgeon to be found. Mr. Colles, that practical and excellent author on Venereal disease so often alluded to in this little work, justly observes, there is no class of complaints which does not occasionally fail to present its dis- tinguishing characters, or, presents them so faintly as scarcely to be recognized. Now, it is just this that creates the difficulty; for, when a suspicious or irregular sore presents itself it is hard to tell whether it is one of these Venereal sores which has failed in exhibiting its distinguishing character, or one of a Pseudo-syphilatic kind. This bastard sort of Venereal we are now consider- ing is supposed to be a compound of Venereal disease, partially cured by mercury, blended with some other disorder of the constitution, such as Scrophula. The great source of this kind of disease is the use of mercury by unskilful people. Being known almost to every one that mercury will cure the Vene- real disease, persons of every grade of ignorance pre- sume on this and give it indiscriminately and ineffi- ciently. There is scarcely a shoeblack who will not prescribe it to his acquaintance if he is fool enough to take it, and hence, almost exclusively, that per- plexing host of pseudo-syphilitic maladies.. The Venereal,—Diseases mistaken for it. 153 fact is, although mercury is the safest and most cer- tain remedy for the cure of Venereal disease, there is no article in medicine which requires a more skilful and experienced mind in prescribing it; or, closer attention to the rules which wiU be given in the following chapter for its proper management. And it may.be further added, neither is there any one disorder which calls for profounder knowledge in every single department of medical education, than that for which mercury is so peculiarly the remedy—the Venereal disease. Who then can wonder that these perplexing and distructive cases should so frequently occur. Mercury, therefore, given ineffectually, fails in curing the Venereal disease;.in this case, after a time, it re-appears, and mercury is again resorted to. Still, however, given as before, the disease again appears, not perhaps exactly in the same form, for being interrupted thus repeatedly, it looses much of its external Venereal character, so that it is not so easy to tell whether it is Venereal or not. At length however these repeated ineffectual modes of giving mercury break down the constitution, and thus excite in it whatever malady it should be disposed to. This. very frequently, is some or other form of scrofula, and this disorder, scrofula, blending with Venereal, forma this Pseudo-Syphilis—appearing, sometimes in the bones, or in blotches on the skin, and sometimes in little ulcers on the penis. 154 Venereal,—Diseases mistaken for it. Now, in order to detect the nature of these sores. it is necessary to ponder well both over the history and the treatment of each case. It is of course essential to ascertain that there has been, at some time or other, real Venereal disease; and also, that mercury has been given for its cure. It is also ex- pedient to be certain they do not arise from stricture, for a person may have had Gonorrhoea and Venereal too, and, the Venereal being cured, these sores may arise from stricture, the result of the Gonorrhcea. With respect to the treatment of them, I can do little more than speak of this in general terms. It consists in giving very small doses of mercury and continuing it for a considerable length of time. This also is combined with such remedies as support or recruit the general health and strength,—such aa Bark, Quinine, or SarsapariUa. Change of air, espe- cially to the sea side, has been found exceedingly useful. Also, all that has been said on the utility of maintaining a regular and healthy state of the stomach and bowels in diseases generally, applies especially to this case. Indeed, I have known many obstinate disorders of the genital organs greatly bene- fitted or entirely cured simply by attending to this one object, and I should consider that that case wa9 under no unpromising course of cure which was under the simple treatment of the Rhubarb and Soda Mixture, together with the Blue Pill, as directed in * page 149, and continued for some months. In such Venereal,—Diseases mistaken for it. 155 a case the mixture might be omitted after a week or two, or only resorted to as the state of the bowels might require, while the blue pill should be continued regularly every other night. 156 Mercury,—Its use and abuse. CHAPTER XL On the use and abuse of Mercury, with rules for its proper management in the cure of Venereal. disease. This subject will be rendered plain and useful by arranging it in the following order.—How far is Meicury to be considered a specific for Venereal disease;—What is the general effects of Mercury on the constitution;—Is any preparation necessary for its safe and successful use;—What is meant by Salivation;—How far is salivation necessary for the cure of Venereal disease;—At what period of a mercurial course should salivation be produced ;— What is the best form of Mercury to use, and on what principle should the dose be regulated ;—How long should a course of Mercury be -continued;— What are the difficulties which now and then occur to interrupt a regular and satisfactory course of Mer- cuiy;—and, what are the bad effects which Mercury may possibly produce, denotingthat it disagrees and must be discontinued. These therefore will consti- tute the different sections of this chapter. How far Mercury is to be considered a specific for Venereal disease,—is a subject well worthy of consideration. Now, if by specific is meant a reme- Mercury,—Its use and abuse. 157 dy which always, without exception, and under every variety of circumstances, cures any particular dis- ease, then Mercury has no such claim, for there is no such remedy in nature.—The Peruvian Bark is said to be a specific for the Ague, but there are cases of ague continually occurring which the Bark will not cure; and beside, the Bark may be given so in- judiciously, and under circumstances so adverse to it. that, if given before these latter were removed, it would not only fail to cure the ague, but exasperate or make it fatal;—and this is just the case with re- gard to Mercury in Venereal disease. All that can be justly said of Mercury then is this,—that it so generally cures the Venereal disease as to be given for it with the greatest imaginable confidence; but, that there are cases (rare indeed to meet with) in which it seems to fail; and also, there are many occasional circumstances so adverse to its good effect as to require to be removed before it can be entered on, or persisted in, with safety ; and further still, that even then, and in all cases, Mercury is a safe and efficacious remedy, only when given in a certain ju- dicious way and manner. To give this remedy then in a safe and efficacious manner, it is necessary next to consider,— What is, the general effect of Mercury on the Constitution.—The general effect of Mercury is to excite the constitution; so much indeed is this the ease as to induce a fever, called Mercurial Fever, 158 Mercury,—//* use and abuse. This febrile state, however, in general, is but a slight disturbance, and does not interfere with the ordinary pursuits of business. But, it may however easily be imagined that the habit and constitution might be so excitable and full, as to be quickly thrown into a high degree of fever, and hence the necessity of preparation for a course of Mercury. And it should also be observed, that in this case, it would not only be to endure this higher degree of fever without occasion, but also to miss the object for which Mer- cury is taken, for these higher degrees of fever seem to prevent the curative effects of Mercury, so that, after a certain period, the disease is often seen to return, and this how long soever the Mercury may have been continued.—By preparing the constitution for the effect of Mercury, also, we succeed in curing the disease with much less of this remedy than otherwise would be required.—I feel I cannot lay too great a stress on the necessity of preparing the constitution for a course of Mercury, for I am per- suaded it is too little insisted upon, and that this is the cause of much unnecessary inconvenience as well as failure even in the cure of the disease.—It therefore becomes a proper enquiry,— What is the preparation necessary for the safe and successful use of Mercury.—In general, all that is required is to reduce the system mode- rately by repeated doses of some purging medi- cine, and to observe a lower diet. Of course th« Mercury,—Its use and abuse. 159 extent to which this should be carried should be de- termined by the healthful state and condition pre- sent. Persons wrho are most frequently the subject of this complaint are the young, the robust, and san- guine, and these always bear depleting weU; but even in the more delicate this preparatory measure should never be totally omitted. In these latter cases, for instance, I would recommend to take a purgative medicine for four or five days at any rate, but not in such a manner as to weaken and unfit for business. Almost any active purge will answer, but the best of all is that of Epsom Salts and Antimony. as directed in page 47; and. the next to this is the Senna and Salts; but even Epsom Salts alone will do. Of course it should be repeated once, or twice, 01 thriee in the day, just as it may prove active or otherwise. With the more robust however I would continue the purging longer, carry it on brisker, and the diet lower. In many of these latter cases also, perhaps in all of such, it would be advantageous to undergo a copious bleeding, but this is not insisted on, especially as such a measure might lead to un- wished-for inquiries and attention. Keeping this effect of Mercury in mind, we likewise see the propriety of avoiding labor and exertion, both of mind and body, as far, at least, as can be done conveniently. There is no doubt but it would be better for eveiy one, upon entering on a course of Mercury, to keep his room, as well as lower his diet, 160 Mercury,— Its use and abuse. and there are cases so bad and complicated as to render such a measure absolutely necessary ; but with the great majority of patients this is altogether out of the question, all that is required being that they keep as much as possible in the house in wet cold weather, particularly at night, and that they avoid unnecessary labor. I have thought it as well however just to state the fact, leaving it for every wie to do the best he can in this respect. Tiiis also seems the place to mention, thai a course of Mercury should-not be commenced while a person is laboring under other disorders; or, rather, that there are many complaints which require first to be removed, and others which should be remedied and relieved if possible. Inflammatory complaints of the chest, and Dysentery, and Diarrhoea, are of the former kind, while Consumption, Dyspepsia, and a general low emaciated condition, are examples of the latter. If, for instance, you were to begin and persist in a course of Mercury while there was pain in the side or chest, with a cough, or what is called Bron- chitis, it is ten to one if it did not convert this malady into incurable consumption. Such symptoms there- fore must be first removed by bleeding, blisters, &c.; and, if commenced while laboring under Dysentery, or Diarrhoea, the Mercury would increase such mala- dies, and never affect the constitution beneficially; (hese therefore also must be first removed by such medicines as Rhubarb and opiates, suitably repeat- Mercury,—Its use and abuse. 161 ed.—So also if Consumption or Dyspepsia were pre- sent, a watchful attention should be paid to the effect which Mercury might have upon these symptoms, so as to be ready to control or mitigate them. And, in the last case—a low emaciated nervous state of con- stitution—this should be recruited by such means as change of air, milk diet, SarsapariUa, and the like, before a course of Mercury could be entered on with safety and success. But, beside the general effect of Mercury on the constitution, and the necessity of preparation for. it, it has also a particular effect upon the salivary glands of the mouth, called Sali- vation. This shall therefore next be stated,— What is meant by Salivation.—When Mercury is given for the cure of Venereal disease, it is begun with in certain medium doses, and repeated daily, or night and morning, with the expectation that in a few days, it will produce a soreness of the gums; but, if this is not produced, nor any indications of it, then the dose is rendered larger, or some other pre- paration of the medicine is superadded, and thus it is increased, under certain limitations, until this soreness is produced.—But a simple soreness of the gums is not a salivation,—it is only the commence- ment of it, and, if the Mercury were left off as soon as this soreness should be first complained of, it is probable it would soon get well, when the diffi- culty of re-producing it might be great. At an* rate, it is not likely it would be done without a larger 162 Mercury,— Its use and abuse. quantity of Mercury than otherwise would be need- ed. It is therefore deemed expedient to continue with the Mercury, either in the same or smaUer doses until a moderate but perfect salivation is established.—Now, in a case of moderate but perfect salivation, we observe the following:—the gums are swollen and tender—inclined to separate from the teeth, and sometimes a little ulcerated; the cheeks also near the double teeth are inclined to ulcerate, and present a kind of leaden color ; further, there is always some degree of pain on eating solids, so that the softer articles of food are naturally selected; the spittle too has a disagieeable taste and smell, and is more or less increased in quantity, giving rise to fre- quent spitting, and, not unfrequently, it will drivel from the mouth at night while sleeping. All this however does not come to pass at once. The first symptom of a salivation is a disagreeable or coppery taste in the mouth, with a slight degree of swelling of the gums, but after this it may be several days, although full doses of Mercury are continued, before it completes this state. At the same time, nothing is more desirable than to secure this point, for then the danger of the disease, as well as the various untoward cirsumstances which frequently attend a course of Mercury, may be considered to have passed away, while the cure of the disease is safe and certain.—It is true, that, in many cases, if the Mercury were now to be entirely omitted, this tenderness might still increase for many days, and Mercury,—Its use and abuse. 163 at length attain to a fuU and satisfactory salivation; but which, it is still more probable, might die away and get quite well. On this account it is deemed advisable to continue on with Mercury, although at the risk of causing a greater degree of soreness of the mouth than might be wished for. Not that I approve of violent salivations; quite the contrary, as will presently be seen; but it is not an easy matter always to hit the exact degree we aim at. Perhaps there is no period in the Ireatment of Ve- nereal disease which requires more steadiness and caution than that between the first effect of Mercury on the gums and its full effect upon the salivary glands. While therefore it is wise to be firm in continuing on with Mercury under the complaint of soreness, it is necessary to be watchful of its more slow or rapid progress. If, for instance, this soreness of the gums were stationary, the dose should be increased;—if steadily advancing, it should be diminished; but if rapidly progressing, it should of course be omitted. The necessity of Salivation.—Having shown what Salivation is, and, withal, that it is an incon- venient thing, it seems proper next to enquire how far it is a necessary part of the treatment.—There are those who consider this effect as an essential point in the cure of Venereal disease by Mercury and who are not satisfied if it be not produced however much or long continued the Mercury may 164 Mercury,—Its use and abuse. have been. But this is going certainly too far, for I have met with many in whom it was found impos- sible to produce a salivation, and yet the disease was perfectly and permanently cured. Allowing this, however, there still remains no doubt but a saliva- tion marks the salutary influence of this medicine, and affords the only proof that it is acting favorably on the constitution and disease. And further "still, it is a fact, that among those in whom the disease returns after having taken Mercury, it is found that in a groat majority of such a salivation never was produced, or properly maintained. Witnout agree- ing therefore with those who consider a salivation to be absolutely necessary for the cure of the disease by Mercury, I do not scruple to recommend it as an important object. With respect to those cases in which it may be found impossible to produce a sali- vation, and the means to be pursued in such, these I shall notice when I come to the subject of pecu- liarities of constitution. At what period should Salivation be produ- ced.—This also is a point of some importance, for if it be produced too suddenly, it cannot be depended on, and there is a disadvantage if. delayed too long. The most favorable period at which a salivation can be produced is within the fourth and tenth day from the commencement of the course. To accomplish it, if po-rsible, within this period is an object even of anxiety, and to this end the dope is lo be promptly Mercury,—Its use and abuse. 165 and regularly augmented, as will presently be shown. What form of Mercury is the best to use, and on what principle should the dose be regulated. —The best of the preparations of Mercury perhaps is that in the form of ointment, (page 48) but there are many objections to the use of this, as have been already stated. Some form of mercurial medicine 10 be taken internally, is generally more convenient. Of this kind the Blue Pill, or Calomel, is in common use ; but, that which I prefer, and use myself almost exclusively, is The Specific Pill, (page 49). This is a mild, safe, convenient, and effectual form of mercurial medicine, of which a sufficient quantity to cure any case of Venereal disease, however long it has been standing, is put up in my little private chest, and which I frequently forward to the most distant States. With respect to the dose of mercu- rial medicine, this, as might be supposed, must vary under different circumstances, and must be dimin- ished or increased as it may be found to act on dif- ferent constitutions. There is however a general or ordinary dose to begin with; this, in a common case, and healthy person, if the ointment is used, 'is half a drachm to a drachm, every night; if it is the Blue Pill, ten grains divided into two pills; if Calomel. from two to three grains, made into a pill or powder ■ or, if it is " The Specific Pill,'1 of these, three are an ordinary commencing dose. They are to be taken 166 Mercury,—Its use and abuse. nightly. The great object, however, as I have said before, is so to increase or diminish the dose as to bring about a moderate but perfect salivation in a given time; and, to show how this is done, I will now suppose a case, and treat it exactly ,as I am in the practice of doing daily. I will suppose a healthy young man with a Vene- real sore (a chancre) on the penis, and that it has been there a week or two; also, that he has taken several doses of active purging medicine, and has put himself upon a lower diet. He now begins by taking three of " The Specific Pills" at bed time. These we do notexpect or wish to produce any effect at all at first; if however they should happen to purge, and continue to do so, this should be checked; it can be easily done by taking five or six drops of lauda- num, or a tea-spoonful of paragoric once or twice; or, if he should become costive, he might.obviate this by taking a seidhtz powder, or any laxative pill or medicine he choose. But, about the fourth day, it should be enquired if any effect upon. the mouth has been produced. Perhaps-there is none—no disagreeable taste or tenderness of the gums is yet complained of. This therefore gives occasion for an increase of the dose, and now four pills are given instead of three. Yet, having waited two days more, there still is no complaint. This would imply a degree of dullness of the constitution to the effect of Mercury, and would authorize its freer Mercury,—Its use and abuse, 167 ase. Accordingly, two pills would be directed to be taken in the morning in addition to four at night. This would make six specific pills in four-and-twenty hours, and should be considered an ordinary full dose of Mercury, It should be therefore watched more closely. But now however, perhaps in two days from the latter dose, making eight days from commencing, the gums become a little tender, and there is a coppery taste complained of. Now, this is the moment which demands judicious manage- ment.—If we were to stop the Mercury here, as I have observed before, the soreness of the gums might still go on and ultimately reach a state of perfect saliva- tion; more probably however it would not do so, but in two or three days would get quite well. In this case we should find it difficult to renew the soreness, nor could we do it without the use of much more Mercury than otherwise would have been required. Indeed it sometimes happens when this opportunity has once been suffered to escape, it cannot be pro- duced again without a fearful quantity of Mercury. Many content themselves with the simple quantity. they have used, instead of its peculiar effect, and thus become exposed to the horrors of a deep Venereal taint. But this is easily avoided. In the present case, after the eighth day, we find the gums a little swelled and sore, but not sufficiently, and therefore we continue on. Here it may be a question,—shall the same dose be given? When the dose under which the soreness happens is very large, is may be 168 Mercury,—Its use and abuse. diminished; but if in a day or two the soreness does not seem to be advancing, it must be increased again. In the present case the dose is large and may be di- minished. The two pills in the morning" are there- fore now omitted, and in a few days more a greater degree of swelling- of the gums, with an increased flow of spittal, now completes the salivation, when the medicine of course is omitted altogether. The accomplishment of salivation, especially if within the regular and proper time, may always be esteemed a source of satisfaction and congratulation. It is an inconvenient thing no doubt, but now the cure is completely in our hands, and with a little management, any considerable degree of inconve- nience may generally be avoided. It now becomes our chief concern to avoid an excess of soreness on the one hand, and prevent its getting totally well upon the other. Accord- ingly, we must omit the medicine,as long as cir- cumstances may permit. Sometimes a mild and salutary spitting will continue for ten or fourteen days without additional medicine; at others, not only will the spitting cease, but the mouth get well in three or four. Whenever the spitting cease en- tirely, and even when it rapidly abates, although the -mouth may yet be sore, the pills should be resumed, not however in the same full dose, but just in such as may be sufficient to re-excite the spitting and Mercury,—Its use and abuse. 169 maintain it. This is much more easily done if the medicine is resorted to before the mouth gets weU. It may be of use to mention here, that whenever the mouth gets well too soon, and there is a»difficulty in re-producing it, nothing will act so well as Calo- mel. Of this, three grains, with one of Cayenne pep- per, repeated twice or thrice a day for a day or two, will generally effect the object. Thus, by increasing or lessening the dose of pills, we endeavor to perpet- uate a moderate state of salivation for as long a period as the nature of the case demands, or as will pre- sently be determined on. It may be remarked I have been particular in de- fining the exact degree to which a salivation should be-carried; I have been so from observing that I was not sufficiently explicit on this subject in my last edition. Anxious that no one should suffer the least degree of unnecessary pain or inconvenience, it is possible I there leaned too much upon the cau- tious side. I have now however given my directions more decidedly, as well as my reasons for them. And now, the nature of a salivation and the necessity of it having been discussed, the question naturally fol- lows,— HOW LONG SHOULD MERCURY BE CONTINUED— This, as might be supposed, can be determined only by the circumstances of each case. There are how- 170 Mercury,—Its use and abuse. ever certain circumstances or conditions of the dis- ease which uniformly require a difference as it re- gards the period of a mercurial course. For instance, the circumstance of its being a recent or an old dis- ease,—the readiness and regularity with which a salivation is produced and kept up,—the kindly dis- appearing of every single symptom,—the circum- stance of having taken mercury ineffectually before, •—and the occurrence of any other diseases, blending with Venereal.—All of these require a difference as to the length of time that Mercury should be con- tinued, and therefore will properly form the basis of what I have to say upon the subject. 1st.— The circumstance of its being a recent or an old disease.—The shortest courses of Mercury, no doubt, are those required in chancres—the first form in which Venereal disease appears; and, as a general rule, the older the disease the longer the use of mercury is required.—Some forms of the disease however, it is considered, require more protracted courses, independently of the time it has existed ;— thus Venereal sore throat and eruptions of the skin require a longer course than chancre, and ulceration of the bones, longer than sore throat. It is quite impossible to fix the exact time required in any one of these, but, as a general rule, it may be said, that a chancre would require a four or six weeks course of Mercury; sore throat and eruptions of the skin Mercury,—Its use and abuse. 171 from six to seven weeks; and ulceration of the bones from eight to ten weeks. 2d.— The readiness and regularity with which a salivation is produced and kept up.—If there should be found an unusual difficnlty and delay in producing salivation, notwithstanding the dose be properly increased, so that salivation should not ap- pear for two or three weeks, then it would not be, safe to limit the course as has been suggested, but rather to reckon from a few days previous to the time'of salivation. So also if anything should occur to interrupt a course of Mercury, even if salivation had commenced, on a removal of that cause, that is to say, if any considerable interval had elapsed, the former time is not to be taken in the account, but the reckoning is to be made as though Mercury had not been given before at all. 3d.— The kindly disappearing of every single symptom.—Although I have given a general rule for the continuance of Mercury in every given case, yet it may happen that after this has been observed, and the disease apparantly been cured, there will remain one single symptom, demanding a further continuance of the remedy.—The most frequent cir- cumstance of this kind is a hardness remaining in the skin after the healing of a chancre. Now so sure as this is overlooked, or slighted, so sure are we exposed to the possibility, nay, to the probability 172 Mercury,—Its use and abuse. of a second appearance of the disorder. But on continuing the use of Mercury on this account it is not necessary to carry it on so far as to maintain a state of salivation. Indeed, unless the hardness be considerable, it is not necessary to continue it inter- nally at all. What is now required is merely to rub a portion of Mercurial ointment into the indurated part, once or twice a day, and continue to do so until it is absorbed and made to disappear entirely. Per- haps a portion of Mercurial or blue ointment, as it is called, not larger than a pea, well rubbed upon it with the finger until it is quite absorbed, and repeat- ed nightly or night and morning for a week or two may be sufficient; but, however long it may be re- quisite, let it be remembered, it must not be laid aside until this hardness entirely disappear. It will be seen I lay a stress upon this treatment, and I do so from observing that many persons*are in- clined to slight it. Having gone through the course prescribed, and feeling well, they do not like this further trouble. Bui what is the trouble of thia triffling attention to secure an object of such import- ance ; or even if it were ten times greater where is the remedy ! This hardness is the peculiar charac- teristic of a Venerial soie. In fact we are often obliged to wait for its formation, in doubtful cases, before we can tell whether an ulcer really be Ve- nereal Or not; how reasonable then to suppose that while any of it should remain, the essential nature of the disease should be unextinguished ; and, if so, Mercury,—Its use and abuse. 173 it will most assuredly appear again at some future time. I repeat, therefore, that while any degree of positive hardness after the healing of a Venereal sore upon the genital organs should remain, thin milder use of Mercury must not be laid aside. 4th.— The circumstance of having taken Mercu- ry ineffectually before.—It is well known that tha constitution does not bear a Mercurial course so well the second or the third time, as at first, espe- cially if it have been carried on severely. You can- not so easily nor so certainly produce a salivation; more time and larger doses are generally required ; and when it is considered that a second or third sa- livation should always be carried on a week or two longer than a first, it would seem that this circum- stance is the cause of a considerable protraction of a course of Mercury. 5th.— The occurrence of other diseases, blend- ing with Venereal.—This circumstance gives oc- casion for a longer course of Mercury than any other. The most common examples of this complex dis- ease, are those in which it becomes blended with scrofula. In this, the Venereal sore, completely merging into the character of scrofula, loses much of its own external form and appearance. Now it is well known that scrofulous constitutions do not bear the influence of full and decided doses of Mercury, but require that it be administered in small and cautions 171 Mercury,—Its use and abuse. doses. This therefore accounts for these longer courses in complex forms of Venereal. I am happy however to add, that Mercury, even in these worst of cases, if given thus judiciously, is attended with the happiest effect. But now, having shown the importance of saliva- tion and the extent to which it should be carried, it is next my duty to advert to certain circumstances which now and then occur and make it difficult to obtain this object. These I will mention in italics, and will explain the proper management of Mercury in each. In doing this, however, I must first ac- knowledge, that, for a more clear and definite view of the nature of these several difficulties than I once possessed, I am much indebted to that excellent author on Venereal, Dr. Colles of Dublin, whose very words, indeed, cm some occasions, I shall use myself. 6th.—A Dysenteric state of bowels.—This is no uncommon thing before a salivation is produced ; but whether it is before or after, it shows the Mer- cury is acting on the intestinal passage, rather than the salivary glands—the only proof of its favorable action or the disease itself. In this case, therefore, stop the Mercury a day or so, and take five grains of Rhubarb with ten drops of Laudanum for two or three times ; or, have a four ounce bottle of mixture made, of Tincture of Rhubarb half an ounce,—Tine Mercury,—Its use and abuse. 175 ture of opium eighty drops,—and peppermint, or any other water, enough to fill the bottle, of which take one quarter immediately after every Dysenteric stool. This very seldom fails" to quiet the bowels, but, if it do, an injection of thirty drops of Lauda- num in half a tea cup full of warm milk and water, and repeated perhaps once or twice, may be said to be a certain means, and those who happen to have my little patent syringe, contained in the chest for Gonorrhoea, will find this the most convenient, as well as expeditious mode of cure. The Dysentery being removed, of course the Mercurial medicine is to be resumed. 7th.—A state of soreness of the gums which is not followed by a salutary spitting.—It may hap- pen that about the usual time, a slight degree of soreness of the gums and smell of the breath occur ; and yet, although the Mercury is continued for sev- eral days, no increased flow of spittal is observed. If the gums are now examined it will be found they are not soft and swollen as in a regular saliva tion, but their edges are more inclined to ulcerate. Indeed, the ulceration of their edges is the only change they appear to have undergone. Such cases also are attended with too much fever. Now, if we were to go on with the same dose of Mercury, we should only increase the ulceration and the fever, without producing salivation. In this case therefore we do not increase the Mercury, but diminish it. 176 Mercury,—Its use and abuse. In fact, this condition is a proof of an over dose of Mercuiy. If therefore you were taking five pills at night, take now but two, and these only every other night. Also, if the "fever were considerable, lower the diet and drink freely of warm tea, or any thing that would induce a perspiration and abate the fever. You might further take thirty drops of antimonial wine, two or three times a day, as a fever medicine. By these means you will soon convert this spurious, into the true and genuine kind of salivation. 8th.— When the effect of Mercury falls upon the throat, rather than the salivary glands.—In this case the soreness is referred to the thrpat, and is commonly attributed to catching cold. On looking in the mouth a high degree of inflammatary redness and swelling is to be seen, particularly on that cur- tain-like part suspended from its arch and behind it. We see also upon the tonsils (two glandular bodies, situated, one on each side the back of the mouth) a superficial ulcer or two, covered with a whitish or greyish matter. Now, in this case, always stop the Mercury immediately. If you were to persist in it you would endanger the distruction of these parts. In the mean while the throat may be frequently gargled with port wine and water, to which a little honey and vinegar may be added. In a few days, either with or without the gargle, the throat will get decidedly easier and better, and then you are to re- sume the Mercury in smaller doses. By this treat- Mercury,—Its use and abuse. 177 ment, Dr. Colles observes, " I have seen in some of these cases, a regular salivation come on, but in a few others I could not succeed in producing this de- sirable result, the renewed action of Mercury pro- ducing the same condition of the throat; such cases, however, are conducted safely through the Mercu- rial course, by watching them closely, aud taking care that the inflammatory state should not be al- lowed to rise high." By this is he means, that the moment the inflammation raises high, the; Mercury should be omitted for a day or two and then resum- ed, to be again withdrawn on the recurrence of such a state. 4th.— The gums beginning to be affected at the proper time, but do not proceed to a salutary spit- ting, notwithstanding the medicine is continued.__ In ordinary cases the same dose of Mercury which produces a beginning tenderness of the gums, will, on continuing it, mature that state into a mild but perfect salivation; in some instances, however, it will fail to do so; neither in this case is there any disposition to ulcerate the gums, or to excite fever, the only thing remarkable being its stationary and limited effects. Here it is necessary to increase the dose ; but, as it is not usual for Mercury when it has gone so far, then to stop, it may happen that some other form of the medicine may suit that particular constitution better, and therefore the additions made may be in some other form of the medicine. Accord- 12 17S Mercury,—Tits use and abuse. ingly,iflhe pills have been taken, we may now use the Mercurial ointment,—continuing the same dose of the pills as before. Half a drachm of the ointment therefore may be now rubbed in at night, and this in two days more may be increased to a drachm, lessening this large dose of Mercury as we may see the mouth advancing towards a salivation. 5th.— When fever is produced instead of sali- vation.—This is still another and a very different effect, and also one which shows the Mercury is disagreeing and must be stopped. Here it pro- duces no effect upon the mouth or throat at all, but in a few days from its commencement, the skin be- comes hot, and the pulse quick, with much feverish restlessness. This feverish state, unaccompanied by any marks of salivation, is a proof that the Mercury given, whatever the dose may have been, is too much for the constitution. The course to pui- suethenis to omit the Mercury and use such means as are calculated to abate the fever; cool air, gentle purging, and any diaphoretic or fever medicine are calculated to effect this object. Then, after a little time, or when the strength has been recruited, the Mercury should be resumed in smaller doses, and repeated at longer intervals, (perhaps in half the usual dose) and this only every other night. It is also proper on recommencing Mercury to give twenty or thirty drops of antimonial wine two or three times a day, to keep the bowels open with an Mercury,—Its use and abuse. 179 occasional purgative, and, if convenient, to take a warm bath or twro. With these means you will be able gradually to/increase the dose of the Mercury and at length induce a favorable salivation. This fe- verish state, it should be observed, is not unfrequently the consequence of hastily plunging a patient into a Mercurial course without the preparation for it already insisted on, especiaUy in a young and vigor- ous person. But, in addition to the difficulties already men- tioned, there are others also arising from peculiai and very opposite constitutions,—the one being too sensible, the other too insensible to the effects of Mercury. 6th.—A Constitution too sensible to the effects of Mercury.—It will happen that some individuals will become salivated on taking one single dose ; but this is a kind of salivation that cannot be relied on. Without reasoning on the subject, which, indeed, would be to very little purpose, we must rely upon experience, and this teaches that those who become salivated on taking the first or second moderate dose of Mercury are not thereby exempted from future forms of Venereal disease ; it behooves therefore to enquire how such singular constitutions should be managed. The directions of Dr. Colles on this head are remarkably plain and correct. He says, "such a patient should be directed to keep very 180 Mercury,—Its use and abuse. " much out in the open air, to take a nutritious diet, " and two or three glasses of wine daily; the dose " of the medicine also should be reduced to one " fourth, and an interval of one, two, or even three " days left between each. When we have proceed- " ed thus for a little while, we may prescribe larger " doses, or shorten the periods between them, so as " to induce a salivation, which will then occur with- out any unfavorable symptom." The salivation thus produced must be maintained and regulated as has before been shown. But I cannot in this place forbear remarking, how correctly these means accord with the principles on which the utility of a prepa- ration for a Mercurial course was urged in a former part of this chapter. Was it, for instance, in order that Mercury should make its early and salutary im- pression on the mouth, that the preparatory means of purgatives, and low diet, and warm clothing were directed; so, when that effect should show itself too early, the opposite means are introduced, and, by cool air, a generous diet, and a little wine, this premature effect of Mercury is delayed and the constitution brought to bear the necessary quantity. I should not however have pointed ont this beauti- ful consistency, but for my solicitude to press upon the mind the utility of preparation for a course of Mercury,—persuaded as I am that its omission is a terrible evU, and that it is far from being suffi- ciently enforced. Mercury,—Its use and abuse. 181 7th.—A Constitution too insensible to Mercury. —This when it happens is a more perplexing case. It differs from all the preceeding. For instance, it presents neither ulceration of the gums, nor inflam- mation of the throat, nor fever. Indeed, its pecu^ liarity consists in presenting no effect at all.—It has been shown that in giving Mercury in this complaint, the object is to induce a salivation, and this within a certain time if possible. With this view a regu- lar system of enlargement of the dose is early acted on, that is to say, to a limited extent. Thus pro- ceeding, therefore, it generally happens, that after a second or third increase of the dose some effect upon the mouth wUl be discernable, but in this case there is none; nor is there any on the constitution, by which we might be warned it is acting in one way or another. It is frequently now supposed that it is the fault of the medicine—the particular prepa- ration that has been used—and therefore it is chang- ed, or some other is added to it, as calomel, or cor- rosive sublimate, but to no purpose. Others have gone on to increase the dose to an incredible, and I might add, dangerous extent—to the quantity of half an ounce of the ointment, for instance, every night and morning, together with large doses of calomel or Blue pill. But a frequent consequence of this has been, either an alarming degree of debil- ity and fever, or a violent salivation, suddenly com- ing on; and, what is still more melancholy to superadd, without curing the disease; for, after 182 Mercury,—Its use and abuse. these excessive salivations it is no uncommon thing to find the malady return. It is not a violent, but a moderate and gentle salivation that can safely be relied on for the cure of Venereal disease. Now the following is the most judicious course in such a case. After increasing the dose for thiee or four times, and perhaps adding some other form to that originally used, without the slight- est visible effect, except it may be some degree of wasting of flesh and strength, then stop it altogether. This advice is given on the supposition that the dose was larger than was suited to the constitution. It is a fact, however difficult to explain, that in some constitutions, small doses of Mercury will produce the best effect, when large ones exhibit no visible effect at all.—Neither must the Mercury be resumed for ten or fourteen days, or 'till it is sup- posed the influence of the former quantity has sub- sided and the strength has been recruited. Be- fore a second trial also the patient should be bled, and freely purged, and put upon a lower diet. The Mercury now being recommenced, perhaps in half the usual dose, a kindly salivation generally comes on. But, if that should not occur in ten or fourteen days, then the Mercury is to be increased in the ordinary way and manner, and this until it reach a full, or more than full and ordinary dose.— Six specific pills, with half a drachm of ointment every four and twenty hours, might be considered a Mercury,—Its use and abuse. 183 lull and liberal dose, and beyond this, it should not be increased with a view of bringing on a salivation at any rate. This course however should be con- tinued a week or two longer than the usual time, and then, although not so satisfactory as in an ordi- nary case of salivation, may be relied on as a per- fect cure. We have the best authorities for stating that there are constitutions which do not admit of salivation, but yet admit of the cure of Venereal disease by Mercury, cases of which they have given in detail. I do not scruple therefore to say, that cases of this kind, treated and tried with Mercury in -the manner here directed, are to be considered safe and secure, and that the failures in attempts at saliva- tion are owing to "peculiarity of constitution."— There is one thing in their treatment however, that would seem to merit more particular attention than in ordinary cases, and that is, the perfect disappear- ance of every symptom, particularly the hardness which is sometimes inclined to remain after the heal- ing of chancres. Let the Mercury therefore be con- tinued even for a little time longer than usual after the total disappearance of this symptom. Indeed, the perfect and total disappearance of this and every external symptom might be regarded as an addi- tional and valuable proof of the efficacy of the course. But there is still another class of circumstan- ces, or definite effects of Mercury, which show 184 Mercury,—Its use and abuse. it to be disagreeing and demand its immediate dis- continuance. These therefore must foUow in this enumeration. 8th.—r An unfavorable effect of Mercury on a" Chancre, or Bubo, or Ulcerated throat.—In gen- eral, soon after a Mercurial course of Mercury is commenced, the local or visible part, whether chan- cre, bubo, or sore throat, will begin to improve, and after a little further time, more or less rapidly pro- ceed to heal. Indeed, these changes are regarded as a general rule of judging whether the Mercury is acting favorably or no. It sometimes happens, however, that after a chancre or any other local symptom has been doing weU for a length of time, it suddenly alters, and becomes painful, inflamed, and spreading. Now this is the effect alluded to in this section and shows that Mercury is disagreeing. But this must carefully be distinguished from a slight and temporary change, occurring at an earlier period of the course. It is a fact that every one should be aware of, that a chancre will, almost always be a little painful and inflamed, and often spread a little, just at the time when Mercury is about to act upon the gums; but this, in a day or two, improves again. Very different, however, are the circumstances which denote that Mercury is disagreeing. It is then an unequivocal and increasing change for the worse, and, which is a point of great importance to obseive, it is after the Mercury has been proved to Mercury,—Its use and abuse. 185 be the proper remedy, by the previous improvement of the sores. In this latter case the chancre, from looking healthy, filling up, and without surrounding inflammation, on a sudden becomes painful, inflamed, and spreading; or, if a bubo,this, from being slightly tender, would become exquisitely painful and inflam- ed, with fever; or, if it were an ulcerated'throat, this would become inflamed and spread. Such changes indeed would unequivocally prove that Mercury was disagreeing and must be discontinued. 9th.—A Mercurial Rash, covering most part of the body.—This is another circumstance which requires the immediate discontinuance of Mercury. Sometimes, about the period when the gums begin to be affected, and when also there is generally some slight degree of fever, there appears, about the groin or between the thighs and scrotum, a patch of redness, or Rash, which, if not attended to, will soon become extended over the whole surface of the limbs and body. This Rash is not a very serious thing if early seen; but as it commences in parts which are likely to es- cape attention, and is not at first attended with much uneasiness, it is often overlooked a day or two, or until a high degree of pain or itching disturbs the rest and draws attention to it. On examination it then is found that the limbs and body are coveied with a continuous vivid redness, constituting, under 186 Mercury,—Its use and abuse. mismanagement, one of the more distressing and serious effects of Mercury. It does not seem to de- pend on any given quantity of the medicine, for it has been seen under very small as well as larger doses. There is however a particular period of a Mercurial course to which it is chiefly, if not entirely confined. This period is just when the Mercury is about to affect the gums, and when, as I have ob- served before, there is always some degree of fever present. When a spitting has commenced it never need be feared. And this remark indeed applies to most of the other untoward effects of Mercury ; when once the constitution is fairly under its influ- ence it is comparatively safe; and hence the great necessity of watchfulness at this particular period. It is on this account I always wish to see my patient every day or two, (if it can be done conveniently) from the time of commencing Mercury, until a spit- ling is established ; but where this cannot be com- plied with, I guard against these incidents by pro- viding this little book for their perusal.. Nothing can be more cruel, if not criminal, than to give a person Mercury and leave him ignorant of these possible effects, and the peculiar management they require. What then should be thought or said of those who advertise their drops or pills to cure Ve- nereal disease, and send away the unsuspecting pur- chaser without the least conception of these various incidental circumstances. Should such a rash as this appear, the following t Mercury,—Its use and abuse. 187 is the course to be pursued. Immediately stop the use of Mercury. If you were to continue it, one of the most distressing eruptive diseases, with great debili- ty, and even danger, would result. In lieu of this, give a cooling purgative medicine and repeat it so as to produce a moderate effect for two or three days together. If under this the eruption should in- crease, avail yourself of cool and even cold air ; also dress lightly.—Keep to put in the open air and ventilate your chamber as far as the weather may permit. With respect to the eruption itself, any thing that cools and affords comfort may be availed 'of; this is sometimes accomplished by wetting clothes with cold water and applying them ; at others, by dusting the part with common starch or oatmeal; if the skin become excoriated, as it sometimes will, then some stiff ointment to prevent the linen stick- ing to the part is good—such as equal parts of bees- wax and suet melted together and spread on cloth. The shirt and sheets have sometimes been spread over with this composition. In this place however I am more anxious to prevent the malady by showing when the Mercury should be stopped, than to direct about its cure.—When it disappears, the Mercury must be resumed, in small doses, paying particular atten- tion to coolness. It will also be expedient frequently to watch the skin, particularly those parts which fold and lie together, as between the thighs, and oroin; and should any thing of this kind again ap- pear, withhold the mercury for a day or two again, IS8 Mercury,—Its use and abuse. to recommence it as it fades away again. By this attention to the skin, even in cases where it thus returns, it may be kept so limited, as to allow of the perfect cure of the venerial disease by mercury. 10th.—Red pimples on the wrist.—This is very much of the nature of the former,—it makes its ap- pearance at the same period of time (just as the mercury is about to effect the constitution) and re- quires the same positive discontinuance of the medicine. It differs only in appearing, not in the form of a rash, but in little pimples, and beginning, not in the groin or folds of the skin, but on the wrist and back of the hand and fingers. Such pa- tients generally think they have got the itch, and, indeed, it is often taken for it by others. It is men- tioned, however, separately, as it forms another po- sitive rule for discontinuing mercury, for being so unlike the former it might not be regarded as a dis- order equaUy requiring a discontinuance of the medicine. A few days employed in gentle purging and low diet is generally sufficient for its cure. 11th.—An excoriation of the skin in certain parts of the body.—This differs from the former two in beginning, not with a rash, nor with pimples, but in a simple excoriation, as if the patient had been chaffed. The parts more usually thus effected are also those between the thighs, or scrotum, or groin. If this be noticed on the onset it will consist Mercury,—Its use and abuse. 189 simply in excoriation, limited to the angular fold of the part, but if overlooked it will spread extensively, and give out a copious discharge of very offensive humor. Now, if this were nothing really but a little chafe, it would be indeed a very trifling matter, but it is found a very different thing, and if not attended to at first, will become a very painful and distressing malady. There is no such thing as sleep at night, neither can you move one limb upon another with- out agonizing pain, and this too, may continue many days, perhaps weeks together. Under this effect of mercury, the first thing, as before, should be the discontinuance of the medicine; and the next, some soothing application to the part. Opiates are found to be of very little use, nor does purging afford any great relief. The chief resource for ease in this complaint is a suitable application to the part itself. As a remedy of this kind, a powder composed of equal parts of " Lapis Calamindris" and of Starch, finely powdered, is the best. This should be put into a muslin bag, the part well dusted and covered with it, and then a fold of soft old linen nicely laid upon it, between the two surfaces of the skin. An- other thing which has been found to answer an ex- cellent purpose is the Black wash, (page 44); lint, kept wet with this lotion should be applied to the parts affected as above discribed. This effect of mercury is supposed to be the conse- quence of giving it in too large a dose, and therefor, in 190 Mercury,— Its use and abuse. reassuming the'mercury, it must be given in a smaller dose ,and, steadily, but cautiously increased. There is however one general remark to make upon the sub- ject of resuming mercury—it is, that when it is to be given again, it should be resorted to as soon as the circumstance on account of which it was omitted, has abated. If it were delayed a longer time than this, the other and necessary effects of mercury would also die away, so that a greater length of time, and a greater quantity of mercury would be required to re-produce them. 12th.— The effects of Mercury when it disa- grees icith the Constitution generally.—Of all the untoward effects of mercury, this is the most worthy of attention. Heretofore I have spoken of this medicine only when it has exerted an injurious effect on some particular part, shown by inflamation, fever, and affections of the skins; but now we come to speak of its effects when exerted in- juriously on the constitution generally—when it may be looked on as a kind of poison. However excellent and valuable a medicine mer- cury is, it must be acknowledged, that, if misman- aged, or misapplied, it may be turned to very bad account. But this in fact is saying nothing more than what relates to every valuable remedy. Indeed, the more valuable a remedy, when properly used the more dangerous when ignorantly abused. With- Mercury,—Its use and abuse. 191 out attempting to describe the pecuhar nature of the constitution with which mercury disagrees, I will merely detail the symptoms by which it may be known. In a case where mercury disagrees, about the time when it might be expected to show itself upon the mouth, a remarkable degree of general prostra- tion is complained of, with a sense of anxiety and palpitation of the heart; there is also frequent sigh- ing, partial or universal trembling, occasional vomit- ing, a pale contracted countenance, and a general sense of coldness. All these circumstances, to one acquainted with the laws of physical vitality, would argue a great reduction of its power. Indeed, every one would be aware of this, but still might not be quite aware that they arose from mercury, and therefore, might not so promptly discontinue it. My present object therefore is to state this fact so clearly that those who have this little book can scareely overlook or slight it. Not that this is a common effect of mercury by any means; on the contrary, it is exceedingly uncommon ; still it is pro- per that every one who undertakss the use of mer- cury should be acquainted with it, though it were only as a possibility. It is not in the active and pecu- liar effect of any medicine,but in the ignorance of such that the danger lies. With respect to what should be done under circumstances of this kind the first thing of course is to omit the mercury. Even the 192 Mercury,—Its use and abuse. dress and bed clothes might be changed lest they should contain any portion of it. Next, he should be careful to avoid the least exertion, such as even rising suddenly, or getting out of bed without assis- tance. Cordials in small but frequent quantities should be allowed; but above all, exposure in the horizontal posture, and in the free and open air, both day and night, should be rigidly insisted on. If this treatment prove successful, mercury must not again be had recourse to for three or four weeks at least, and not then if the health and strength be not re- stored. If however it be determined on, give it in :he following cautious manner:—Begin with doses very small, and interpose a gentle purgative about every second day. Be careful also that he take daily, but gently, exercise in the open air. If by this means the salivary glands should be affected and a spitting follow, the danger may be considered passed, and the cure as certain as though nothing of this kind had happened. With this I finish what I had to say upon the use and abuse of mercury, having also mentioned with especial care, every difficulty that can possibly at- tend it. For the latter, however, I am aware I shall be blamed by some, on the ground that many of these evils are of rare occurrence, and therefore that I am creating unnecessary fears. But to this I would reply, that many consult me from a distance; others, who are not, within the reach of Physicians Mercury,—Its use and abuse. 193 who have seen much practice in this complaint; and not a few obtain my little private chest on going to sea, and of necessity rely upon it in every time of need. What therefore could such do in the event of any of these untoward effects of Mercury. I grant most cheerfully that many of these evils are of rare occurrence, and that the management of Mercury in the cure of this disease is easily ren- dered safe and certain; but to this end the rules which are here given should be carefully considered, and especially should every possible untoward effect be known and rightly managed. With what pre- tentions to propriety or justice then could I have put this little volume into the hands of such, and omit to mention any single one of these effects. Indeed, there is no part of this little book from which I anti- pate more usefulness, or derive more conscious sa- tisfaction, than from this very chapter. With this feeling, therefore, I will endeavor to present these difficulties in a still more clear and useful manner in the following kind of table:— A CONDENCED VIEW OF THE DIFFICULTIES WHICH NOW AND THEN ATTEND A COURSE OF MERCURY. 1st. A Dysenteric state of the bowels, showing that the Mercury is acting on the intestiral pas- sage, rather than on the gums. 2d. A state of ulceration of the gums instead of a swelling and salutary spitting. 194 Mercury,—Its use and abuse. 3d. The effect of Mercury falling on the throat and curtain of the mouth, producing a high de- gree of redness, and whitish looking sores, like thrush. 4th- The gums beginning to be affected in the proper manner, but not proceeding to an increas- ed flow of spittal, notwithstanding the medicineis continued. 5th. When a feverish state of body is produced in lieu of salivation. 6th. A constitution too sensible to the effects of Mercury. 7th. A constitution too insensible to Mercury. 8th. When Mercury produces an unfavorable effect upon a chancre, a bubo, or an ulcerated sore throat. 9th. When Mercury produces Rash upon the limbs and body. 10th. When it produces pimples on the wrist like the itch. 11th. When it produces excoriation of the skin in those parts which fold together, as the groin, scrotum, cj-c. 12th. When it seems to disagree mith the con- stitution generally. These, together with the symptoms which denote their coming on and the proper management of each, have been carefully pointed out. Venereal,--iis Treatment and Cure. 195 CHAPTER XII. On the Treatment of Venereal Disease. A Chancre (a Venereal sore on some part or other of the genital organs) is the most common form of the disease we have to treat, and is the way in which every other form begins. The following is a definition of Chancre :—" A sore of a somewhat circular form, excavated, with matter adhering to its surface, and icith a thickened edge and base."— You must not however expect every chancre to ex- hibit all these points of character; sometimes they do not appear for many days, so that a real Venereal sore may look just like any other sore or abration of the skin ; and sometimes some of these particu- lars do not appear at all. If there is' any doubt about the matter, however, you must refer to Chapter X, "upon diseases resembling Venereal, &c." In a case of recent chancre, the first thing I always do myself is to pinch it up between my thumb and finger, and if I feel a hardness and thick- ening around and underneath it, the question with me is settled—I know it to be a chancre. But, re- member, if this hardness and thickening should not be felt, yon are not immediately to conclude it is not a chancre; for, as I have just now said, this hardness may be delayed in forming. 196 Venereal,—Its Treatment and Cure. Being satisfied however that you have a chancre, what then is'the first thing to be done? Now this naturally leads to a word or two upon the use of caustic. The application of caustic to a recent chancre has been recommended on the principle of destroying its specific action before it has attained a certain matu- rity, by which it can contaminate the system. But this I have always considered a very dangerous speculation. If wre knew for fact that the matter secreted by a recent chancre, at any certain early period, was not infectious, then indeed it would be highly advantageous to cauterize; but this, as far as I kndw, is not ascertained. Neither does analogy sanc- tion such a theory. The case of small pox or vacci- nation may be considered analogous ; here, a poison being innoculated, a pimple forms containing matter; but after the formatjoion this pustule, if it were cauterized, or even removed entirely, this would not protect the constitution. Neither would it in the case of chancre. And here again, in the case of chancre, the Venereal action has gone still further,—it has not only gone so far as to produce a pimple or pustule, but this has broken, and an ulcer, secreting matter, is presented. If, indeed, a part innoculated with Vene- real matter were cauterized or cut out immediately, like the bitten part of a mad dog, before it had insti- tuted any action at all, it might be then depended on; but, as this cannot be, (for we cannot tell that a Venereal,—Its Treatment and Cure. 197 part has been affected with Venereal, until it is shown by ulceration or a pimple), and further, as we have no means of judging whether there is any period at which the matter of the pustule or ulcer is not in- fectious, so we have no ground on which we can rely that the constitution will not be afterwards af- fected, though the chancre be early and perfectly destroyed by caustic. I would not say that in no case whatever is the constitution thus protected, but I would ask, who would choose to risk his own upon this peradventure ? I hold therefore that it is ex- ceedingly speculative and unwise to depend on caus- tic for the cure of chancre.—And this too is exactly in accordance with the opinion of Sir Astley Cooper. After dissuading from the use of caustic, for other reasons, Sir Astley adds, that if caustic should be used, there being no certainty in this means of cure, a course of Mercury must still be entered on, as if no caustic had been used at all. alsHeo then goes on to show the folly of this practice by relating the con- sequences of a case which occurred in a particular friend of his, and which I will give in his own words below (note 23). Note 23.—The case of Sir plication of caustic: I laughed Jlstley Cooper's friend who at him for being so foolisli: the undertook to cure himself by caustic produced a slough, caustic. He states«"A young h^1 cu''ed the chancre, and I person with whom I was in- thought nothing more of the timate whilst I lived with mv ™mj a?C?'- Sometime af- old master, got a chancre, temards I-^mt^ him in the which, to use his own expres- u°u"try!, and asked him how sion. he burned out by the ap- he was ? Fery well now," 198 Venereal,—Its Treatment and Cure. Notwithstanding these facts and reasons against the use of caustic for the cure of chancre, hoAVever, there still are those who practice it. Most of such persons, no doubt, are totally ignorant of its conse- quences ; but there are also those whose opinions are entitled to the highest deference, and who, under certain limited cirrumstances, advocate the use of caustic. Among these, an eminent surgeon in France who has had for many years the'unusual advantages afforded by a large Venereal hospital, he replied, "but I have been in a,nne scrape; I was en- gaged when I left town, to a young bady, the nuptials were to have been soon celebrated, and the business of life com- menced." I involuntarily &*smiled, but he said, "Not quite so merry: when I got. into the country, I had what I conceived at the time was only a huskiness of the throa t, which I had caught from cold. My throat becoming more painful, I looked ihio the glass, and perceived that I had a large sore on the ton- sils, decidedly syphilitic. You may conceive howl felt; I wrote to the lady that I was unwell, who, exceedingly hurt at such news, came and nursed me while I underwent a course of mercurial treat- ment, (.she being perfectly unconscious of the cause of my complaint,) by which meanfe I was quite restored, and the marriage ceremony was celebrated." The fol- lowing remarks of Sir Astley are so much to this point that I must conclude with them. He then goes on—" It was a proper punishment for his fol- ly. The application of caus- tic to a chancre does not ren- der a Rerson safe from its eHccts, for, if the sore be a chancre, the syphilitic poison must have been admitted into the constitution. I will tell you what treatment you should pursue : as soon as a patient applies to you tor this complaint, you should ask him if he wishes to be, pro- perly cured at once, by a sim- ple mercurial treatment, or have the chancre cured with- out it, and run the risk of having secondary symptoms occurring at a future period. His answer will be—for God's sake, give me what is proper now for my cure, without submitting me to the chance of being laid up a second time with this complaint." Venereal,—Its Treatment and Cure. 199 has lately recommended it, and has endeavored to point out the particular circumstances under which it may or may not be had recourse to. Happy indeed should I be to be made acquainted with any particu- lar circumstance, on which, being prese*nt, I could rely with confidence for the cure of Venereal disease by caustic; but, after what I have seen and known, it must be a pretty good and solid kind of evidence that would get my consent to a dependence upon caustic inFany well marked case of chancre. There is one thing at any rate which should be observed upon this subject:—it is, that it is onTjrm the case of recent chancre it can be reasonably thought of by any class. After it has existed, for instance, some weeks, by which time it will have acquired the peculiar hardness of its edge and basis, it is of course out of the question altogether. The Treatment of Chancre,—is commenced by preparing the constitution for the use of Mercury. Purging, a low diet, and as much quietness or free- dom from excessive bodily labor as he can command, is recommended. Salts, or almost any purging me- dicine will do, but the Antimonial Mixture (page 47) is the best. If any further hints respecting prepa- ration are required, these will be found in page 158. About a week is usual! y occupied in this way, but this is not considered lost; for, during this purging treat- ment the disorder cannot make advancement, while 200 Venereal,—Its Treatment and Cure. its effect will be to lessen the quantity of Mercury required, and shorten the period of the course. From the commencement of this treatment apply nothing to the chancre, (unless it is in a state of unusual pain and inflammation) but lint, wetted with cold water, if it is any where underneath the foreskin; or spread with spermaceti, or any simple cerate, if it is exter- nal, on the prepuice or the penis. You therefore now begin with Mercury.—Begin with three " Specific Pills." and repeat them every night. You need not look for any sensible effect from these at first; if any should occur, as purging or costiveness, these may be corrected as pointed out in page 166. But on the fourth or fifth day, per- haps some tenderness of the gums, or coppery taste — Sn the mouth, may be complained of; if not, increase the dose to four at night. In two days further, should no effect be felt upon the mouth, take in addition, two pills in the morning. This would bring the dose to six pills in the four-and-twenty hours. This being an ordinary full dose, may be continued a few days more. But if this, in three days further, making the 9th, were to be followed by no soreness of the gums, nor any bad effects, (for which refer to page 174) then add to this treatment from half a drachm to a drachm of mercurial ointment, in the manner described page 48, and continue it for four or five days more. If still no soreness of the gums should be produced, you then are to consider it a Venereal,—Its Treatment and Cure. 201 case in which the constitution is peculiarly insensible to Mercury, and treat it as directed in page 181. Above however I have described a case which very seldom happens. In general, long before this dose of Mercury is attained to, the gums become a little tender and the taste is coppery. Whenever this occurs a spitting may be looked for. To en- courage this, the dose must be continued, perhaps a few days more, but when the gums are further swol- len, and perhaps a little ulcerated, and the flow of spittal is increased—then stop the medicine. The object now will be to keep this soreness within tole- rable bounds. On the one hand, then, you must not let it get quite well, nor, on the other, make it too sore, and this you can easily accomplish by omitting repeorating the medicine, or by diminishing or in- creasing the dose as you see fit. If the present ten- der state of the gums and spitting should continue, which it frequently will do for eight or ten days, you may omit the medicine for this time, or give it in smaller doses. A better practice however, and one which I adopt myself, is to wait a few days only, and then renew the medicine in the same full dose, and not diminish it again, unless from an increasing soreness of the mouth, I see it necessary. Thus I avoid a very common error,—that of allowing the mouth to get too well. What I mean by too well is, a total absence of swelling and tenderness; I do not take the spitting into the account;—this may 202 Venereal,—Its Treatment and Cure. cease while the efficacy of the medicine is secured, but if the swelling and tenderness also cease, we have no proof that the Mercury is acting with its full effect. Thus we proceed for a period of four to five weeks from the time of beginning with the Mercury. During this period, we seldom have occasion to apply any thing but lint and cold water, or sim- ple cerate, to the chancre itself. If the patient is particularly anxious to heal the chancre, the black wash (page 44) is as good a thing as can be used. But it is better not to hasten its healing, but rather allow this to depend on the medicine taken for the cure of the disease. It is astonishing to see the immediate and beautiful effect of the Mercury upon a Venereal sore, as soon as the constitution acknow- ledges the general influence of the medicine by a tenderness of the gums. Just at the time when this is about to happen, however, the chancre, for a day or two, may appear a little worse and feel a little ^ painful, but as soon as the tenderness advances, it suddenly improves, looks red and healthy, and more or less rapidly fills up and heals. In general, before this course of Mercury is com- pleted, the chancre will have healed, leaving nothing but the color,—no hardness to tell where it had been seated; but sometimes an ulcer will remain unheal- ed. In this case, however, it is no longer a Venereal Venereal,—Tte Treatment and Cure. 20;-! ulcer, requiring the further use of Mercury, but a common indolent sore, requiring only common stim- ulating applications. Spontaneous sores of this kind, which, by ignorant or designing people are always called Venereal, frequently occur upon these parts. but there is nothing of Venereal in them. The best way to treat such sores has been pointed out, (page 148) but I will here repeat it in a word or two. Take white vitriol in powder on your damped finger, and hold it to them for a minute or two, then dress them with lint wetted with cold water, or spread with simple cerate. The powder may»be repeated every other day. Or, touch them with the Blue Vitriol, or with the Lunar Caustic, every'other day, dressing them as before every night and morning. But the chancre may have healed, and left a hard- ness where the ulcer had been seated.—Now this, of all things, is what I wish to draw attention to. It has been particularly noticed in page 172, but here too I will repeat, it never must be overlooked. You need not however continue the Mercury internally, but apply mercurial ointment to the part.—A quan- tity a little larger than a pea should be well rubbed into it night and morning, until it is removed. Rub the ointment into it with the finger until it is quite absorbed, and repeat it, however long it may be needed, until this hardness is perfectly removed. And now, the course of Mercury being quite com- 204 Venereal,—Its Treatment and Cure. pleted, and every symptom perfectly removed, many people are anxious about the Mercury—to get it out of the system, as they call it, but this is quite su- perfluous. It is far better to let the Mercury pass off itself, which it always naturally does in a little time. All that is required is to take a little more than common care against catching cold. 11 is a fact that Mercury leaves a person rather more suscepti- ble of cold for a week or two, on which account, if exposure to wet cold weather could be avoided, it should be done ; but, if not, it can safely be encoun- tered by clothing suitably and warm. If however any remarkable degree of nervous weakness, or Dyspepsia, or irregularity of bowels should be left, these would be best removed by the strengthening laxative pills, No. 2. Indeed nothing will be found more useful and restorative in a con- stitution weakened and exhausted from any cause, than these restorative aperients. They should be taken once a day, immediately after a meal, either breakfast, dinner or supper, and in such a dose as just to keep the bowels a little more relaxed than natural. Generally, however, it is seen that a course of Mercury, given and conducted in the manner here described, leaves a constitution better than it found it. But, the treatment and cure of a common simple case of chancre having now been shown, it is neces- Venereal,—Its Treatment and Cure. 205 sary here to state, that there are certain circumstan- * ces frequently starting up which demand particular at- tention. These I will proceed to mention, severally, and begin with, An inflamed and irritable Chancre.—This is sometimes seen in a very high degree, and, if Mer- cury were given before it were reduced, it would endanger even the very member itself. Naturally and properly, pain and inflammation do not belong to chancre, and if any be present, it is owing to ac- cidental causes. Many bring these on by habits of irregularity, excitement, and intemperance, and in others they will spring from a full and plethoric habit. When a chancre is highly inflamed, the skin around it is of a fiery red color, the parts are swol- len, and the chancre very sore and spreading. Never give Mercury in such a state as this. The best means of removing this high degree of inflammation are those made use of in preparing for a course of Mercury, so that here they answer a twofold purpose. Especially is it advantageous, if possible, to rest. Indeed, in some cases the conse- quences are so threatening and dangerous that every consideration of secrecy must be laid aside and ab- solute rest in bed enjoined. More generally how- ever, smart and repeated purging with the antimonial saline, or senna and salts, (page 47) with low diet and partial rest, together, if the patient be fuU habit 206 Venereal,—As Treatment and Cure. ed, with a copious bleeding, will be sufficient. At the same time, a soft bandage, constantly wetted with a cooling lotion should be applied. It may take many days before this inflammatory state be thoroughly subdued, but however long it be, Mer- cury must not be given until it is removed. With respect to the irritable chancre, this may be said to be the case when it is exquisitely painful, of a dark color, and evidently spreading. To this, other applications are lequired. Lint soaked in the black wash, or in tincture of myrrh, or tincture of opium, should be applied, and over this a poultice of grounds of beer, or a plaster of simple cerate.—Also, bark, ammonia, and opium should be given freely. These and the doses of them will be seen in chapter 3d, "on remedies," page 53. But I need not here do more than merely mention them, for in such a case I should certainly advise that medical aid be sought. Venereal Bubo.—This is a swelling in one or more of the glands of the groin, seldom more than one, and is frequently observed in connexion Avith a chancre. There is always some degree of pain and stiffness with it, but if this be only moderate, no application will be needed. The mercurial treat- ment is to proceed exactly as though there was no swelling, and as soon as the constitution is affected, the pain will lessen and the swelling gradually de- Venereal,—Its Treatment and Cure. 207 cline. But if the pain and throbbing of the bubo should be very great, with inflammatory redness, and some fever, then the use of Mercury must be delay- ed, or, if commenced, omitted, while attempts are made to reduce this inflammation. These attempts are made by such means as are proper in other in- flammatory affections, and which have just been mentioned, viz.—rest, purgatives, and low diet. To the part itself, any thing which will abate the pain is proper. The cooling lotion mentioned under "reme- dies," or one made with weak brandy and water, is often very useful. Many apply leeches with very good effect, and after these a common poultice. Also an opiate, or Dover's powder, should be taken to assuage the pain at night. All these, and the doses of them, are carefully mentioned in the chapter upon reme- dies.—if; notwithstanding all these means, the swell- ing still goes on to suppurate, that is, to form an abscess, it should be opened and treated in the com- mon way.—Let it only be remembered that Mercury is not to be given while matter seems to be forming, nor even after it is opened, until the pain and in- flammation have subsided. After this, the mercurial course is to be continued as though it had not hap- pened. It should be also hinted that these abscesses are not always found to heal so quickly as chancres, but will often continue for many weeks after the Vene- real disease is cured. Neither is the hardness or 208 Venereal,—Its Treatment and Cure. scar, which they are very apt to leave, to be regarded in the same light as the hardness of a chancre. In fact, these bubos seldom go on to form an abscess but in constitutions that are not exactly healthy, such as those embued with scrofula, or affected from derangement of the organs of digestion, and therefore require means calculated to correct this state and to improve the general health and strength, as Quinine or Bark, with the strengthening laxative piUs, No. 2. A£ to such things as panaceas, and the like, this is al- together peifect quackery.—Endeavor to recruit the strength by rational means,—as a suitable and rather generous diet—the regulation of the bowels and di- gestive organs with the restorative aperient pill, and, adding to these a moderate share of patience, nothing need be feared,—time will remove the remaining hardness. Inflammatory Swelling of the Foreskin.—If a chancre becomes inflamed and irritable from any cause, it is likely to induce a swelling of the foreskin to such an extent as to prevent its being pushed back over the head of the penis, or, if pushed back, it cannot be drawn forward again. (The former of these cases is called a phymosis, the latter, a para- phymosis,—words however I will not use, if I can help it). Both these states are attended with dis- agreeable consequences. In the first, the sore or chancre cannot be kept clean, nor can the discharge attending escape,—it therefore becomes irritating Venereal,—Its Treatment and Cure. 209 :nd thus adds to the inflammation of the parts : and in the other, the penis itself being swollen, the. foreskin acts the part of a tight ligature behind the head of the penis, preventing the return of the blood from it, on which account it swells still more, looks purple or blackish, and, not unffequently, mortifies and comes off. It is therefore particularly necessary to point out what to do in each of these cases. In the first place, then, never begin with Mercury Avhen the foreskin or head of the penis is thus swollen or inflamed; if it should have been commenced, leave it off if these should happen to come on. I have often said already, never give Mercury in any case of high inflammatory local disease. This is the principle to act on, for it might happen that the foreskin might not admit of pushing back, and yet no high inflammatory symp- toms might be present,—no high degree of redness, nor excessive pain, nor feverish complaint: in this case the Mercury should not be discontinued, for, as it proceeds to exert its benign effect, the chancre beneath the foreskin will heal, and all will be re- stored to order and a natural condition. But the particular treatment of this case consists in local management. One of the first things is to wash away the matter from beneath the foreskin, and to keep the chancre clean. For this purpose the patent syringe contained in the chest for Gonorrhcea is admirably suited, but those who have not this 210 Venereal,—Its Treatment and Cure. apparatus must procure a common syringe. Warm; water, or soap and water, will answer one good purpose—the removal of irritating humors, and will also sooth the parts. It can scarcely be used too thoroughly. Throw up the water with sufficient force to distend the skin, and hold it in a little wrhile. In short, do it in any way which you may suppose best suited to wash away the matter. It should be repeated night and morning for the sake of cleansing, but if its soothing effect should also seem to benefit, it may be repeated oftener. But,beside the cleansing effect of warm water,a heal- ing one may be also superadded. Nothing in gene- ral answers this purpose so well as the Black Wash, (page 44). It may be used warm if convenient, but this is not essential.—As a healing, cooling thing, the powder No. 1, as used for Gonorrhoea, is found an excellent injection, while the other numbers are valu- able when any kind of gentle stimulant is required. At the same time, and especially when the inflam- matory redness is considerable, cooling lotions (page 44) should be applied,—wetting a strip of linen with them and rolling it round the penis. Of course, rest, purging, and low diet, are of great importance. It is a good thing to keep the penis from hanging down if possible. I will only add, that I have seen the ap- plication of a few leeches to the inflamed and swol- len foreskin of the most signal service. Venereal,—Its Treatment and Cure. 211 With respect to the treatment of the other case— the foreskin pushed back and remaining fixed—the same, general plan which has just been pointed out is equally applicable, with the addition however of the means to be adopted to bring the foreskin for- ward again; but these, having been already given on this case in Gonorrhoea, (page 62) they can be re- ferred to. I must also further add, that in this case, being much more dangerous than the former, and, especially, as it now and then requires a little inci- sion of the skin to liberate and relieve the head of the penis, I would always recommend that a surgeon be consulted. Venereal Warts.—These sometimes follow after chancre, as well as after Gonorrhoea, and are called Venereal, though they frequently have nothing of Venereal in their nature. It is a curious thing how- ever'that they sometimes secret a humor which communicates the same to others. Thus persons having them have married, and after a time the wife has had a similar production. And these sometimes increase to a great extent in women,—they have been known to occupy a considerable space in the female passage, giving rise to much confusion and inconvenience. These warty excrescences are either hard or soft. The mildest remedy to the soft ones is the white wash,—pieces of linen dipt in this and kept applied 212 Venereal,—Its Treatment and Cure. by bandaging or otherwise. A better thing however is to touch them with a drop or two of the muriated Tincture of Steel, for two oi three days together. Mercurial ointment, applied on lint, will also cure them. The hard warts should first be poulticed and then touched daily, or every other day, with blue Vitriol, or Lunar Caustic. If they have any kind of neck, the most expeditious way of cure is to snip them off with a pair of scissors, and afterwards touch the part with caustic. On looking over what has now been said upon this subject, there yet seems one remark to make upon the use of Mercury in the cure of Chancre. It re- lates, especially, to when it should be discontinued.— I have said, that Mercury never should be com- menced when a chancre is attended with high in- flammatory symptoms; I now would add that it should never be continued, but immediately discon- tinued, whenever such appearances occur in the pro- gress of its cure. It generally happens that when a chancre or any Venereal symptom does well with Mercury, it goes on progressively to improve until the cure is perfectly accomplished; but, if instead of this, after improving for a time it suddenly changes in its appearance, and inflames and spreads, depend upon it Mercury is disagreeing, and it would be in vain and dangerous to expect it would re-as Venereal,—Its Treatment and Cure. 213 sume a healing state under the continuance of Mer- cury.—Either the Mercury is acting too powerfully on the system, or the Venereal nature of the disease is cured, and Mercury is no longer needed; at any rate it is disagreeing, and must now be discontinued. 214 Venereal,—Sore Throat. CHAPTER XIII. On Venereal Sore Throat. It has been observed that chancre is the form of the disease in which Venereal first appears, and is therefore called its primary form; and that when a chancre is only healed and the disorder not eradi- cated from the constitution, in a certain time, it ap- pears again, not however as at first, on the organs of generation, but in some other part, and this is called its constitutional or secondary form. The secondary symptoms of Venereal disease may appear almost on any part of the body, but they far more frequently first appear in the throat or on the skin than any other. In ordinary cases there is but little pain attending the accession of Venereal sore throat. A person per- haps feels a little huskiness, which he may attribute to catching cold, but this increasing, he is led to examine it in the glass, when he is surprised to see an ulcer there. The most frequent situation of this ulcer is the tonsil glands. These are two roundish bodies on each side of the back part of the mouth, between that curtain-like fold which is suspended from the roof. It will be observed that this divides as it descends, and at the bottom. Venereal,—Sore Throat. 215 between this division, the tonsil glands are situated. Now, on one or both of these, which are also swollen and red-looking, an ulcer will be seen. It looks as if a part of its substance had been dug out—the edges overhanging—the ulcer also looking foul, with a yellowish thick matter tightly adhering to it. There is generally some pain felt, particularly on swallow- ing the spittle, and also running upwards towards the ear. and sometimes down the neck even to the shoulders. This is a true picture of a genuine Venereal ulcer in the throat; it may however differ materially and yet be venereal. But an ulcer in the throat ever so exactly corresponding with this picture, must not, on account of its appearance alone, be called venereal,—it cannot safely and certainly be called so, unless its history be traced to some abso- lute prior venereal affection. With regard to the treatment of Venereal sore throat, nothing more can be said than has been di- rected for the cure of chancre, except that the Mer- cury should be continued a week or two longer. The same preparation for a Mercurial course is ne- cessary, as well as the same occasion to discontinue it in the event of high inflammatoiy symptoms and appearances. In general the action of Mercury should.be kept up for eight or nine weeks, in Vene- real sore throat. If any one should be induced to make it shorter, in consequence of the kindly heelin°- of the sore, in all probability, after a few weeks, it would 216 VENEREAL,T- in the throat, a little lint, roll- rounding parts, which woulu ed pretty firmly in the eve of a §lve unnecessary pain and silver probe is to be dipped suffering. into the liquid, and this gent- Venereal,—Sore Throat. 219 night. There are milder applications which it would be as well to mention also, (note 25) 2nd. An ulcer on the back of the throat below the level of the tongue.—When we do not discover a sore above, Ave should see if there is one below the level of the root of the tongue. If there be an ulcer here it is most desirable to ascertain it, for in this place it is very apt to creep lower still and fix on the top of the wind pipe, which of all places is most dangerous and fatal. An ulcer low down in the back of the throat has this peculiarity—it is shallow at its upper edge, but deep at its lower part, A pret- ty sure sign of an ulcer in such a place is, that on eating, a morsel seems to stop at a certain point and can only be got rid of by taking a sip of any liquid. An ulcer discovered in this situation is best treat- Note 25.— A Solution of Lunar Caustic.---Lunar Caustic twenty grains, to water one ounce is a good proportion The Honey of Verdigris— Is another. The Tincture of Benzoes, is still a milder one — When caustic applications are made to.ulcers on the roof of the mouth, they should be made to the edges only, not in the centre, for here the soft parts are so thin that an ul- cer soon exposes the bone, and the caustic application had better not touch the bone. The various things now mentioned may be applied by a piece of lint secured on a probe, or by a camel's hair pencil cut short and stubby — the mouth and throat be- ing washed afterwards with simple water. These toge- ther with the fumigations, page 51, comprehend"all that is useful or necessary as topical remedies for venereal sore throat. 220 Venereal,—Sore Throat. ed by the application of the Muriate of Antimony, as before described. 3d. An ulcer situated at the lower part of the curtain-like fold of the mouth, just as it termi- nates in the base of the tongue.—An ulcer in this place is attended with pain on swallowing, as well as pain shooting upon one side of the head and face ; it is also complained of on pressing down the tongue. This sore is exquisitely sensible, and which sensi- bility should be destroyed by touching it with the Muriate of Antimony, or a strong solution of lunar caustic. 4th.—An ulcer situated high up on the roof of the mouth, behind the curtain, and which cannot be brought into view by any means.—An ulcer is judged to be situated in this part by the voice, which is nasal, and there is not only pain on swallowing, but the person is teased with the frequent desire to draw down the mucus from the nose, which also when coughed up is found tinged with blood. This case too is one which requires the appli- cation of some causlic to allay its extreme sen sibility before the slower and curative operation of Mercury can exert its influence upon it. It is done by a. piece of lint dipped in a strong solution of caustic, and well secured upon the eye of a probe, which is bent up or curved so as to reach it. Venereal,—Sore Throat, 22* The sores I have now described are so many spe- cimens of well marked venereal ulcers. But it should be known that venereal ulcerations in the throat are occasionally seen to differ greatly from these ap- pearances. They are made to do so partly from the improper use of Mercury, and partly from the influence which a scrofulous constitution has upon them. To describe all these differences would be almost impossible as well as useless. The fact itself, however, should be known. But there is one particular state of the throat which it may be as well to mention, being of fre- quent occurrence, which gives rise to much per- plexing and unfounded apprehensions. It has nothing at all to do with venereal, for it frequently occurs in those who never had this malady, yet when it happens to occur in those who have once had the disorder, it is difficult to divest their minds of the fear that it is a remainder of it. This state consists of a thin covering of a whitish or yellowish hardened mucus on the back part of the throat. It is more troublesome and harder in the morning than afterwards in the day, for then much of it will be removed by swallowing and talking. Although this is a very obstinate affection and wUl sometimes continue to give trouble for years, and not improve by any means employed yet it is not dangerous—it is only troublesome. To ascertain the present disease, it is only necessa- 222 Venereal,'—Sore Throat. ry to rub off a portion of the mucus with a bit of lint wrapped round a probe and we shall see there is no ulceration,—the parts beneath only look a little rougher and dryer than natural. It is sometimes benefited by gargling with sea water, or by sea- bathing. Further, there are certain affections of the throat and mouth, which sometimes appear after the perfect cure of the venereal disease by Mercury, and which seem to be the effect of Mercury; and what is very singular is, these affections never appear when Mer- cury is given for any other malady ; it seems there- fore that they are the combined effect of Mercury, with the former, but now cured, venereal disorder. it would only be to harass the mind to say any thing more than merely mention that such may hap- pen. With respect tovenereal ulcers in the mouth, it i* only necessary to say that these mar appear on the gums as well as on the tongue, and on any part of it. These however require no other treatment than a Mercural course as recommended for chancre, to- gether with such local applications as have been mentioned, the necessity of employing which, be- ing determined by their rapidity or the pain, de- manding a more immediate relief than the slower process of salivation would afford. Venereal,— Blotches, Scabs, $c. 223 CHAPTER XIV. On Venereal Blotches, cfc. This consitutional or secondary form of venereal disease, I have placed in order after venereal sore throat, but it should be remarked that the two very often appear together, and sometimes the eruptions will appear first in order, or without the sore throat at all. The word blotches is very often used to express venereal disease affecting the skin ; but it is very far from being confined to blotches or copper color spots; indeed there is scarcely a single order of cutaneous eruption which venereal does not now and then assume, so that it may appear in the form of specs, blotches, pimples, vesicles, postules, turners, branny spots or patches, scabby sores, or open ulcera- tion. It would be quite impossible to give a par- ticular and distinct description of all the various forms of venereal disease upon the skin. In fact their is nothing in the appearance of these eruptions, con- sidered in themselves, that can in any safe and cer- tain manner establish the opinion that they are ve- nereal. This the most distinguished Surgeons art aware of, and in order to form their judgment upon any given case, they always have resource to the 224 Venereal,—Blotches, Scabs, §c, history of the disease, considering especially the man- ner in which Mercury has been given, and observing also, whether there is any other symptoms connected with them of a suspicious or venereal character. This, therefore, shall be the manner in which I will now endeavor to assist my reader in judging of his own or any other case. But first it should be known of these eruptions, that, although there is great variety in the appear- ance of them, there are certain forms wrhich much more frequently appear than others, and there are certain changes which all are more or less disposed to undergo. Perhaps the most frequent form is a branny or scaly appearance, occurring especially in the palm of the hands, or on the head, or the margin of the hair. The next to this in frequency may be that of copper colored blotches, which in time be- come scabby, particularly about the forehead. A Rash, not unlike the measles, is another not uncom- mon form—covering sometimes only a small part, and at others the whole surface of the limbs and body. Pimples and little pustules containg matter might next be mentioned. Venereal eruptions also are disposedjto change in their appearance. If they are allowed to subside spontaneously, which they generally do after some few weeks, at least to some degree, the form in which they re-appear is pretty much the same; but Venereal,— Blotches, Scabs, $c. 225 if Mercury has been given (not however in away to effect a cure,) its re appearance is most fre- . quently in some different form. For instance, if the eruption had been in little pimples, it may now be in little postules containing matter; or if it had been in branny scales, it may be next in larger patches or in scabs. Further, there is a re- markable tendency in all venereal eruptions to be- come scabby and incrust;—thus pimples and scales at length assume a scabby covering, and those which begin in pustules, and naturally terminate in scabs, become exceedingly thick and crusty, form- ing elevations on the skin. There is a period at which venereal eruptions na- turally and spontaneously abate or disappear and re-appear. This is very apt to deceive, as to the ef- ficacy of useless medicines. Frequently such things as panaceas, or other useless things are taken, and if the disorder happens to abate, it is supposed that these are curing it; this however at length turns out to be complete deception. The re-appearance of venereal eruption, atso, as well as its first appearance, is always preceded more or less, with some general feelings of disorder ■ as head ache, or pain in the bones and lassitude which are relieved as the eruption advances. On the going off, and perfectcureof venereal erup- 226 Venereal,—Blotches, Scabs, §c. tion by Mercury, it frequently happens that some spots of discoloration of the skin remain for a long while after the absolute cure of the disease. These time only will remove ; any further use of Mercury on this account, or any applications to them would be useless, and indeed, far worse than useless. Before the means of cure are entered on, it still remains to say a word or two to assist in ascertain- ing whether an eruption really be venereal or not. Many persons, both from far and near, come to me with one single question. After stating a few preliminaries, and showing some specimen of disease, they ask—"isthis venereal?" To this I frequently reply, " I cannot say this moment, but I'll soon find out." I then begin to enter on the history of the symptoms, and see to what I can fairly trace them back. Perhaps it will come out, as it often does,"that the person never had venereal at all, but only Gonorrhcea (vulgarly called Clap)—this of course is satisfactory, and I say at once—" It is not /" Gon- orrhoea never causes eruptions of this kind ;—the remedies which are often used in this complaint may produce eruptions, which however are very different. But supposing it is fairly traced to a venereal affec- tion, and that Mercury has been taken, the next en- quiry is—as to the manner in which it had been Venereal,—Blotches, Scabs, $c. 227 taken; and here I generally find a satisfactory an- swer. Few, very few, indeed, I may say none of those who come to me with secondary forms of venereal disease are found to have taken Mercury in the man- ner directed in the chapter on " The use of Mercury " &c. The most part have never taken it so as to affect the gums at all,—others, have left it off the moment the first tenderness was felt, and those in whom it brought about a salutary spitting, continued it for a period well known to be too short to effect a perfect cure. But, suppose again we cannot be so well assured that Mercury was taken ineffectually. In this case - we naturally look with more anxiety for any other symptom. Now, the one most frequently occur- ring in connexion with venereal disorder is sore throat, and if this appears at the same time and in a way resembling what has been said upon this sub- ject in another place, it will afford a strong corrobo- ration of the fact. The time, too, which may have elapsed from the period of taking Mercury for its cure, is another thing which throws some light upon the subject. Although there is a general interval between the ap- parent cure of chancre or a venereal eruption and the re-appearance of the disease, which may be stated to be fiom eight to ten or twelve weeks, and 228 Venereal,—Blotches, Scabs, $c although this period may be extended even for some weeks more, yet, if an interval of six months for in- stance should occur from the last appearance of venereal symptoms, I should consider this longer in- terval as affording a strong presumption of the per- fect cure of the complaint, whatever eruption or circumstance should follow. After these remarks then, it is presumed, no person would conclude of any disorder he might have upon his skin, or face, that it was of a venereal nature, without considering—first, that he must really have been once the subject of this malady;— next, that the course of Mercury he had undergone had not been satisfactory, at least, not so according to the rules prescribed in this little volume for its management;—and last, that the interval between the former disorder and the present symptoms, is one at least of three or four months. And now, on the subject of the treatment of ve- nereal eruption, I can really say nothing in addition to what has been said on the cure of chancre, only that, as in the case of sore throat, it is to be continu- ed two or three weeks longer than in the cure of chancre. There is one hint however I will give upon this subject. Do not allow the early and kindly disappearing of the eruption to lull you into a false security that the disease is cured, so as to Venereal,—Blotches, Scabs, $c. 229 induce you to shorten the course on this account. There is no form of venereal which so quick- ly yields to the influence of Mercury as some of these eruptions. 230 Venereal,—In the Bones, $c. CAAPTER XVI. Veneral Disease in the Bones, &c. This disorder does not usually appear in the bones • until after it has attacked the throat or skin; but it does sometimes occur soon after the healing of a chancre, without a previous affection of the throat. The parts more frequently the seat of this disease are the hard portions of the long bones—those par- ticularly which are least covered with flesh, as the shins, the bones of the fore-arm and the forehead. The softer parts or extremities of the long bones, as well as the small ones of the hands and feet, are but rarely affected, and then only when the disease has continued along time and the constitution has been distressed with various ineffectual remedies and at- tempts to cure it.' Our business therefore will be to consider it chiefly in its earlier and more common form—that of lumps or tumors on the hard bones, called nodes. Venereal Nodes are attended generally with se- vere pain—remarkable for coming on in the evening and continuing until an early hour in the morning, say till 3 or 4 o'clock, when it abates considerably «o as scarcely to be complained of in the day; as Venereal,— In the Bones, &c. 231 evening approaches however, it returns to its ac- customed or increased severity. But it should be also known, least in any case its absence should mislead in jndging of its nature, that, now and then, the formation of a venereal node is attended with but little pain; also in some instances, anode will commence with a feeling of softness in the swelling, with much pain, but which after a few days becomes hard with scarcely any pain. Nodes are disposed to suppuration—that is, to form into an abscess and break; but this they proceed to very slowly. A node once formed will often re- main for many months without the least change— no discoloration of the skin or feeling of matter; more frequently however, they slowly proceed to suppurate. When nodes proceed thus far the bone itself partakes of the disease, and is along while in getting well. I should also observe that anode, at first, is nothing* mote than an inflammatory state of the membrane which covers the bone, causing the affusion of a little fluid. The treatment of venereal nodes differs in nowise from that of other venereal affections. The Mercurial course however should be continued longer. The constitution, also, in this form of the disease, is fre- quently found to be reduced, and to need the assis- 232 Venereal,—In the Bones, $c. tance which sarsapariUa gives to enable it to endure the Mercury thus long continued. The compound decoction (page 54) is therefore often given with the Mercury,—half a pint, twice or three times a day. Also in consequence of the severity of pain, any means calculated to relieve it before the mercury can be brought to act upon the malady should be adopted. With this view, nothing is so beneficial as a blister applied immediately over it. Do not be induced to open a node because it fluctuates and you are sure of its containing matter. A blister is the proper thing to be applied in this case, which should be repeated in four or five days. Under this plan the matter is generally absorbed and thus a most tedious healing process is avoided. Even when the skin which co- vers it is very thin aud red, a blister will frequently succeed. When a venereal node is cured, the swelling and hardness generally disappears ; but on the contrary sometimes the swelling will remain after the disease is perfectly extinguished,—to be removed only by slow degrees, or even not at all. Thus the cure of venereal disorder in the bones consists in continuing a course of Mercury for a longer period, frequently in conjunction with sarsa- pariUa, and in means adapted for the more immedi- ate relief of pain and suffering—repeated blistering. Rheumatic pains, or those occasioned by the im- Venereal,—In the Bones, $c. 233 proper use of Mercury, must carefully be distinguish- ed from veneral. Those who have been affected once with this complaint are very apt to fear that any pains they afterwards may have must be vene- real. They are further led to this conclusion by re- membering their former pains came on at night. But, although venereal pains are remarkable for their severity at night this is not peculiar to venereal. Rheumatic and other nervous pains are generally worse at night than in the day; a better rule to judge by is the situation of the pain. A venereal sufferer will direct you to the middle of the bones, as the shin or fore-arm ; or to some particular spot on the head or forehead, and if you gently press your hand along the part a roundish swelling will be felt, generally hard and painful to the touch, while those who have Rheumatic or Mercurial pains, complain of pain all over; especially about the chest and arms and down the legs and joints. These are not vene- real. Such patients get better in summer. They should be directed to live temperately and wear warm clothing. The compound sarsapariUa (page 54) is valuable in such cases. Dovers powder at bed time also will afford relief. The bones of the nose and those which form the roof of the mouth, also merit particular notice here. I might have included what I have to say on this subject in the chapter on venereal sore throat, for the disease in these bones often begins with a 234 Venereal,—In the Bones, $c. sore on the soft parts covering the roof of the mouth ; but as it sometimes commences also with little scab- by pustules which appear above the angle of the nose and upper lip or cheek, and sometimes on the mem- brane lining the bones themselves, it comes better in this place. The sores in a venereal affection of the throat most generally appear upon the tonsil glands, but they are sometimes seen upon the roof of the mouth, and those beginning on the tonsils may spread up- wards to this part. It is important therefore to watch these sores, particularly when on the roof of the mouth, for if they spread, the soft parts here be- ing very thin, the bone is soon exposed and so dis- eased as to form an artificial opening between the. nose and mouth. This is always a very serious thing, for the voice is rendered nasal by it, and if it be of any size, a portion of the food on eating is pressed through it, out upon the face. The treatment of an ulcer in the roof of the mouth does not differ from one on the tonsils, ex- cept it should become inflamed on spreading. Ve- nereal sores wherever seated, so long as nothing ac- cidentally occurs to make them otherwise, are very slow in spreading and are attended with very little pain or surrounding redness ; whenever any thing of this kind happens, depend upon it there is some- thing wrong. Venereal,—In the Bones, cfc. 235 Generally, when a venereal ulcer in the throat is doing^ well, soon after the commencement of Mer- cury, the sore will begin to improve, that is, from looking foul and covered with a yellowish mat- ter, it will become cleaner, and little elevated points of .-edness will be seen upon it;—these are healthy granulations, and the.surest presage of its cure. And if this favorable change should not occur before, it is sure to happen as soon as the con- stitution is fully under the influence of the reme- dy-shown by the swelling of the gums and spit- ting. A venereal ulcer in the throat therefore shuold be treated exactly as a chancre, and so long as it does not get worse this treatment should be pursued in the confident expectation of amendment as soon as the. Mercury is brought to act upon the gums and salivary glands. But if, instead of this a venereal sore throat is going wrong and threatens to involve the bones, there are three things which should be considered before we can safely determine what to do;—these are, whether it is cured by an inflammatory effect of mer- cury, instead of the proper one ;—or whether it is a more than usually lapid and spreading venereal sore requiring a quicker effect of Mercury ;—or, whether —its venereal nature being cured, it is not now a Mercurial, instead of a venereal sore. An inflammatory sore throat, the effect of Mer- cury, I have already spoken of, (page 76) In that 236 Venereal,—In the Bones, fyc. case however, there was no previous sore, but little superficial whitish spots, like thrush, appearing upon inflamed and reddened parts. Here, on the con* trary, a sore is first observed, and this, from being very little painful, and having scarcely any redness round it, suddenly becomes exceedingly painful, with high inflammatory redness extensively diffus- ed. Now these inflammatory symptoms may fairly be attributed to the Mercury and we therefore dis^ continue it, at the same time the usual means for abating inflammation should be adopted—purging, low diet, and rest. If any other remedies were re- quired thse would be, bleeding, and antimonial pur- ges, for which see page 47, when the inflammation has abated, the Mercury should be resumed in smaller doses, but increased as might seem necessary. A rapidly spreading Venereal Sore Throat,— is a very serious thing.—I have stated that this is not the natural course of this disease, and when it happens it implies the existence of something very wrong. The cause most frequently observed in cases of this kind is a disordered or weakened state of con- stitution, generally rendered so by habits of irregu- larity, or an unsuccessful and injudicious use of Mercury. The previous treatment therefore should be a subject of consideration, and if Mercury has been taken, it should be ascertained, as near as can Venereal,—In the Bones, $c. 237 be, to what extent. If, upon inquiry, it should seem that the spreading character of these sores com- menced while under the free use of Mercury, it should be discontinued, at least, for a time; or, if Mercury should not have been commenced, it should now be entered on, and in such a way as to bring the constitution within its influence in the shortest time. But in every case the state of the constitu- tion will demand particular attention, whether it be, with a view of recruiting from the effects of irregu- larities, or of Mercury, or, with a view of enabling it to bear that quick and decided influence of this medicine which may now be meditated. Here then we are accustomed to look to the SarsapariUa with much confidence and pleasure. The SarsapariUa is a medicine peculiarly adapted to these cases, inasmuch as it has the following three distinct effects;—it is the best medicine that can be taken to renovate a constitution, depraved and weak- ened from any cause, especially from Mercury;—it has also the power of arresting the progress of Ve- nereal disease, though not of curing it;—and it has the peculiar effect of enabling the constitution to bear that quick effect and quantity of Mercury which it could not bear without it.—In every case of Ve- nereal sore throat, which did not seem to be doing well, whether it was deemed expedient to increase the dose of Mercury, or to diminish it, or to delay its use, I should always advise that sarsapariUa be 238 Venereal,—In the Bones, $c. immediately commenced with. As to the best or most convenient form to take it in, this may be seen page 55.