Ex Libris Jonathani Elmer Ipromet manu Jeripris Jonathn. Elmer’s A Course of Anatomical Lectures Delivered By Dr. William Shippen junr. Professor of Anatomy & Surgery in the College of Philadelphia Anno 1766 Quanta autem existerent consilii solertissimi indicia, su tota hominis fabrica perspecta foret? si corporis totius species et dignitas? Sensuum organa subtillissime fabricata, et aptissime locata. Synop: Meta: Anatomia fundamentum est Medicinae Anomal Anatomical Lectures Lecture 1st: Anatomy avatouia in Greek signifies cutting & by it antiently was meant only the dissecting of bodies, but at present it is implied in a more general sense. Anatomy in respect of its object is divided into human and comparative. Human Anatomy is that which is employed on the human body; and comparative Anatomy is that which is employed upon the bodies of other animals, these serving for the more accurate descriptions of several parts, and supplying the defects of human bodies. Anatomy from its various ends may be said to be of four kinds viz: Theological, Medical, Juridical, and Judicial. The The first consists in an acquaintance with the works of the creator in the human frame; according to Fontanel the study of Anatomy & Autonomy afford the strongest arguments against Atheism. Medical Anatomy is ultimately health, for the presentation of which, restoring it when impaired, by diseases, or even preventing their access, nothing surely is more necessary than a true knowledge of the structure of that frame so liable to be injured. Juridical Anatomy is the determining the causes of suspicious deaths, impotency, barrenness, the true times of pregnancy and delivery, the mortality of Wounds and a multitude of other causes of great importance to be adjusted in account of Judicature. Judicial Anatomy is the determining the cause and manner of the death of diseased persons from a subsequent dissection of the body body; this is of the utmost use in the practice of Physic. Upon the whole then the use of Anatomy in very great, nor is it confined to the bounds of Medicine alone; the Philosopher and Theologist, the Magistrate, Painter and Sculptor are in their respective employments more or less qualified in proportion to the progress they have made in this science; but the physician and Surgeon are the people to whom it is most immediately necessary and who without a perfect knowledge of it cannot do justice to the world in their professions. What the needle is to the mariner, Anatomy is to both these, and we may venture to say that without its assistance, they would be rather detrimental than beneficial to mankind. The Anatomy of the solid parts is by Heister called Osteology and that of the soft parts Sarcology, each of these are subdivided. Osteology or the anatomy of the Solid parts is divided into the anatomy of the Bones called Osteology; Chondrology or the anatomy of the Cartilages; and Syndesmology or the anatomy of the Ligaments. Sarcology or the anatomy of the soft parts is divided into Dermatology or the anatomy of the Teguments; Splanchnology or the anatomy of the Viscera; Myology or the anatomy of the Muscles; Neurology or the anatomy of the Nerves; Angiology or the anatomy of the Veins and Arteries and Adenology or the Doctrine of the Glands. In the human body as a complex hydraulic machine a double inquiry must be made 1st. Into the structure of the parts, this is called Anatomy, 2d. Their functions & the laws of their motion which is termed Physiology Lecture 2d. As the solids are formed out of one principal fluid chiefly, called the Blood it is proper to begin therewith. Of the Blood Blood in Scripture is called the life of the Animal; according to some it is the primum vivens ultemum moriens, its a heterogeneous mass, as is evident from the variety of ingredients of which it is made up, and the various forms it assumes in the animal machine. The blood is composed of three substances viz: Serum, Gravamentum & a coagulable Lymph: We shall consider these in three different manners; first when ocularly examined, 2d. Viewed with a Microscope, and B 3dly: The chemical Analysis thereof. Blood fresh drawn from a sound living animal, upon landing, part of it congeals into a hard coagulum suspended in a yellowish Serum, the upper surface being of a florid color while the bottom is black; the reason of the blood appearing bright and florid at the top is from its being in contact with the Air; this is confirmed by an experiment of Dr. Hunter’s who put a quantity of blood fresh drawn into a vial, & stopt it close; upon standing it all turned of an uniform black color, except a little spot upon the top with which a globule of Air had got in contact. Blood stirred round with a probe whilst Whilst warm, a fibrous elastic substance is obtained, which, put in water turns of a whitish color; this is the coagulable Lymph, is strongly elastic, & is the cause of cohesion in the particles of the Blood, as is evident from the extravasation of the blood after death by dissolution of the cohering particles. The coagulable Lymph is sometimes discharged from the Uterus and by Nurses taken for an Abortion; this error they are sometimes led into from a desire that it should be so. If spirits of Wine be added to Serum, or the same made boiling hot, it rises up, emits fumes, and turns into a coagulum similar to the White of an egg: the fibrous part of the blood is what forms Polypuses Polypuses concretions &c: Blood viewed by a microscope appears to consist of a number of globules, the larger ones being those that tinge it of a red color, &c: therefore chiefly make the crassamentum, are of a certain determinate magnitude being of the same bigness in all animals, in a Sheep as in an Ox, in an eel as in a man. These globules are composed of six smaller or ceruminous ones; and these ceruminous ones are composed of smaller or lymphatic ones; and it is probable there are still lower orders of globules of blood. These globules of blood are of a lenticular form and elastic the largest kind being less than the 1/3000 part of an inch Inch. the crassamentum is supposed to contain 1/3 of the mass and the Serum to make up the other 2/3. Blood chemically analyzed; upon distillation with a slow fire a quantity of Phlegm arises, with the fire increased next arises an Oil and a volatile Salt, the caput mortuum being a fixed alkali and a cretaceous Earth. The chemical proportions of the blood are by Dr. Martin & Boyle recvd. as follows viz: of Phlegm 5/6 of Oil 1/15, of Salt 1/25, of Air 1/20, & of Earth 1/75, part of the whole mass. The specific gravity of the blood to that of rain water is by Dr. Jurin and and Martin reckoned as follows, by Jurin as 1000 to 1054 by Martin as 1000 to 1056 or 1057 or as 10 to 19. The density of blood in living animals is to its density when reduced to the coldness of temperate Air as 134 to 135 or 992 1/2 to 1000. The color of blood is for the most part red, but redness is not a constituent quality in blood, for some Animals have white blood. In the human body the blood is redder & more florid in the Arteries than in the Veins, oweing to the action of the Lungs upon it, for by shaking fresh blood in a vial taken from a vein, it appears of the color of arterial blood. That the blood is is reder in the Arteries than in the Veins. Dr. Hunter proved by the following experiement: he opened the Thorax of a live Dog and kept his Lungs working with a pair of Bellows; and drew a spoonful of blood from each side of the Heart is, from the Vena Cava & Aorta the latter of which appeared the reddest. From the accurate experiements it is found that a cubic inch of rain Water weighs 253 1/3 grains, a cubic inch of warm blood 264 3/4 grains. An Ounce of Blood contains 1,813 Inches, an avoirdupois ounce weights 437 1/2 grains equal to 1,727 inches of water and 1,6526 of warm blood. Lect. *Among these we may reckon Boerhaave instit. vol. 2 the colour of the Arteries are of aligamentous substance and not muscular as is evident from their white appearance and their of elasticity both of which is contrary to the general characteristic of a muscle however we are informed that Dr. Cullen has lately discovered that there are muscular fiber in the coats of the arteries the action of which he thinks assists in propelling the blood onward. J. Cullen likewise says that there is a muscular coat to the arteries as well as Boerhaave & many others. &c physiology [illegible]. Lecture 3d. Of the Arteries & Veins An Artery is a strong, membranous, ramifying, elastic Tube, endowed with pulsation; arising from the left side of the Heart, and terminating in every part of the body. The Arteries are composed of three coats, tho’ some have reckoned four and some five.* The first external coat is very thin the fibres of x which going longitudinal & circular; the second coat is thickest and the fibres of it go in a circular direction; the 3d. coat is very compact and its inside very smooth and even, this smoothness and compactness of the inner coat serves two purposes. 1st. to allow the blood to to pass without hindrance & 2d. to prevent its exudation. The pulsatory motion of the Arteries is a dilatation and contraction of them; the former called Diastole, and the latter Systole, which precedes proceeds from the Heart, besides which they have a sort of aperistaltic motion, as is evident from an experiement of Dr. Hunter’s, who opened alive Dog and cutting off the mesenteric Artery, injected it wth. a warm milk, which he could plainly perceive the Artery to carry along wth. a vernicular motion; to confirm is the more he injected the mesenteric Vein but the milk went no farther than the & the force of the injecting propelled it. There are but two Arteries in the body viz: the pulmonic, which carries the blood through the small circulation, and the Aorta, which carries it to all the parts of the body. The coats of the Arteries are very elastic, and are furnished with blood vessels for their nourishment; the Arteries mostly and all except the Epigastric ramify at acute angles. The commonest diseases the Arteries are subject to, are, Aneurisms and Ossification. Aneurisms proceed from a preternatural dilatation of the coats of the Artery’s and are of two kinds 1st. When the blood is x it is sometimes found in young subjects and is oweing perhaps to a disposition of the constitution to form bony matter. is contained within the coats of the Artery. 2d. when the Artery is burst & the blood extravasated into a membranous bag. Ossification happens mostly to Old people from a weak & slow circulation of the Blood. x Veins are elastic, ramifying Tubes, like the Arteries; except smaller. their coats thinner, and without motion. Phisiologically speaking the Veins begin at the extremities of the Arteries, or more properly speaking they are a continuation of the Arteries reflected back toward their Origin the Heart; but anatomically speaking the Veins arise from the Heart. There There are 7 Veins in the body from which all the rest arise viz: The 2 Venae Cava ascendans and decendans; 4 pulmonary Veins (two from each lobe of the Lungs) and Vena Portarum. The veins are mostly ramified in the same manner as the Arteries, exct. the Vena Portae, and the cutaneous Veins of the extremities, & other parts. The veins of the extremities have valves, but not those of the Viscera; the reason of which is because there is no Muscles in the viscera; hence the use of those valves in the Veins of the extremities is to prevent the blood from going backward as well as x Bellini especially is of this opinion as well as for, to push it forward when the muscle is contracted and the Vein compressed. Of Venesection & Hemorrhages. In bleeding, the blood is supposed to x flow out faster at the orifice than it circulates in common, and to increase the circulation to the part, hence the doctrine of revulsion & derivation is easily understood; thus we find in a Cephalalgia bleeding in the foot causes a derivation to the feet and a revulsion from the Head &c: In Hemorrhages the antients used Ligatures round the joints, wc. stopping the return of of the blood to the Heart checked its impetus, but but by Venesection his ends are answered: e,g, supposing an Hemorrhage at the Nose, Lungs, Uterus &c: bleeding takes off the impetus of the blood & causes a revulsion, at the same time. Dr. Haller thinks this latter method much the [illegible] the Veins are some of them subject to Varices, which are an obstruction, or destruction of the valves thereof. The muscular coat of both the Arteries and Veins are somewhat subject to inflammation & suppuration, but not near so much as the other muscles of the body; this is very wisely adapted to their function, for suppuration of their coats would be attended with fatal consequences often. Lecture Lecture 4th. Of the Lymphatics. Lymphatic or absorbent vessels are those fine ramifying vessels which contain a clear diaphanous Liquor; they take their rise internally from the cavities, as the stomach, intestines, and externally from the surfaces of the skin. The antients supposed the Lymphatics were a continuation of the Arteries dividing them into three classes, sanguineous, venous, and Lymphatic, but, it has very lately been discovered that the Lymphatics are an entire system of vessels by themselves, having no affinity or communication with either the arteries or veins. this This is proved 1: by injections not passing into them from the arties 2: by the motion of the fluid in them and the valves they have; they are called absorbents from their office, which is to absorb the Lymph and other matters and carry it into the thoracic duct or Receptaculum Chyli; where they are all supposed to terminate. Those vessels called lacteals belong to this system; and called Lacteals only, from their carrying a milky chyle: their origin termination and course of their fluids being the same. That the lymphatics are absorbents is evident from their absorbing moist substances rubbed on the skin, as Mercury, Turpentine, Garlic &c: but in a more obvious manner in the venereal Disease, where absorbing D the virus they carry it to the adjacent Lymphatic Glands and cause them to tumify, hence Buboes &c: sometimes the virus causing the glands to tumify and inflame, constricts the vessels beyond the same and prevents the infection from going any farther; hence the cure of the venereal disease sometimes by the suppuration and discharge of a Bubo. Of the Glands. A Gland is a secretory Vessel — the antients called only those Glands which we feel hard movable kernels under the chin and other were until Malpighius by his microscope found the Liver and other substances to be of the same texture, and therefore termed them all Glandular. A A Gland he thought to be made up of little fine round bodies consisting of Follicles which contained the secreted fluid and between which was a parynchemical substance; but Ruysch by his injections found that the Glands were vascular or made up of fine vessels which has been further confirmed by later anatomists. The vessels of the Glands are Arteries, Veins, secretory and to some excretory Vessels Nerves & lymphatics Of Secretion Some have imagined that the secretions were performed by the diameters of the secretory vessels, supposing them to be of the size of the particles secreted; but this theory is subject to these two objections, viz: that the smaller particles will will go off with the larger ones and to the secretion be confounded and in a Jaundice, when once the Bile had got into the Blood it would continually remain [illegible] & the Jaundice could not be cured; others supposed a particular fermentation happened in the veneral glands, & from thence arose the difference in the veneral secreted fluids, and likewise was the cause of the secretion; this theory is liable to the same objections with the former, and therefore the most received opinion is, that the secretions depend upon the particular disposition of the vessels, to the particular fluid it is to secrete; hence arises these Axioms. 1st. That the secretions are carried on uniformly in a living sound Animal. 2d. One secretion increased another is diminished &c: Lect. Lecture 5th. Of the Muscles & Tendons. A Muscle is a fleshy, fibrous, [crossed out] substance, consisting of Veins, Arteries, & Nerves; besides fleshy fibers &c; having more nerves in proportion than another part of the body serving to give notice to the brain of any external stimulus or irritation. The redness of the muscles is not inherent in the fibres thereof, but only oweing to the blood contained in them, of which there is a great quantity, more than is sufficient for their nourishment and may possibly be subservient to their motion. A Tendon is a white compact fibrous unelastic substance. most muscles terminate in Tendons, and the Tendons are by some reckoned a continuation of the fibres of of the muscles to which they belong, only more compacted together so as not to admit the red globules of blood between their interstices: but Dr. Hunter thinks the fibres of the Tendons are not a continuation of those of the muscles, but distinct fibres someway cemented thereto. The muscular fibres are cemented together by the cellular membranes and an intervening glue, & serve for the moving of the solid parts of the body. The Tendons are for the better insertion of the muscles, and of great use in motion; eg: in the Perforans and Perforations of the hand, the muscle arises from the inferior part of the Humerus, and if that was continued down to its insertion muscular, it would render the hand troublesome some and unwieldy, whereas now, the Tendons, being compact & taking up but little space, remedy that inconvenience. Round many of the Joints as the Wrist Ancle &c: there is a capsular Ligament or Frenum which serves to keep these tendons in their right places, and facilitate their regular motion; likewise over some of the Muscles there is a tendinous expansion called Aponeurosis, of much the same use as the preceding Ligament. The muscles may be reckoned of three kinds first Oblong as those of the Arm, 2d. Convex as those of the Heart, Stomach, Bladder &c. 3d. mixt as those of the Abdomen the Pectoral muscles &c: Muscles have their names from their Origin, Insertion, Use Appearance &c: Lect Lecture 6th. Of the Nerves. The Nerves are now by every body allowed to be a system of the vessels, and they are a fasciculi of white fine fibres, arising from the Medulla Oblongata & Spinalis, egressing in pain. Over the Brain are the Meninges, or, 1st. The Dura Mater which is externally, & a thick vascular substance within this & adhesive to the Brain is, 2d. The Pia Mater, which is a thinner membrane; between these two, some anatomists reckon another membrane, extremely fine & reticular which they call Tunica Arachnoides. The Brain is divided into three portions called, Cerebrum, Cerebellum, and Medulla Oblongata, the latter being being continued thro’ the spine of the back is called Medulla Spinalis. The Brain is supposed to be vascular, & its substance of two cortex; external of an Ash color is called Corticalis; internal of a white color called Medullaris. The Nerves are of the same substance with the Brain, and are properly aportion thereof continued to all the parts of the body. The Nerves as they arise in pairs soon after decussate, or change sides as in the Optic Nerves, the left going to the right Eye, & the right to the left; hence a wound, on one side of the head affects the contrary of the body. The Nerves are distributed thro' the body in much the same manner as the Arteries; the one proceeding from the Brain the other from the Heart, but with this difference & difference, that the trunks of the Arteries grow less the more they are ramified together with the ramifications ad infinitum; but the capacity of a constituent Nerve never decreases they being imperceptible, but the number of the likes of the Fascicule decreases in proportion as the bundle ramifies, thus the cords of the Nerves wc. as they egress from the Brain contain an innumerable number of constituent Nerves, decrease in No. but not in capacity ad infinitum in proportion as they are ramified. The Nerves anastomose, but not in the same manner as the blood vessels do, by uniting their tubes but only by their coming in contact with each other; these anastomoses are called Plexuses. sometimes little knots appear in Nerves called Ganglions, some imagine these knots proceed from pressure & inflammation, but this cannot be as they are found found in the Viscera, & in a Foetus where no pressure could happen. Lancesi, reckons the use of these Ganglions is for an an additament to the Brain; because he says more nerves go from them than go to them, but from the substance of these knots not being the same wth. the brain, that cannot be. others think they serve to stop the nervous fluid from flying out at the end of the Tube without the impulse of the will by means of muscular fibres, they being only in those nerves destined for voluntary motion; this also appears to be false. The termination of the nerves is but little known, but supposed to be in every part of the body. The use of the Nerves is for sensation, motion, nutrition, &c: the Brain being called the sensorium Comune to wc. the Nerves carry all the sense communicated to them Voluntary Voluntary motion is acquired by experience, as is evident from a child whose will is frequently contrary to the Act performed. Of the cellular Membrane. The cellular membrane is of two kinds, the one adipose containing fat, the other reticular without fat; it is a net like substance, vascular, very thin and tender, consisting of many cells & its fibres very fine: the cellular membrane is continued throughout all the body, except some of the viscera & is called by some the membrana Musculorum Comunis. The cells of the reticular part of the cellular membrane communicate with each other, as is evident from an Anasarca which is a transudation of Phlegm into the cells, & so from the one to the other, as is evident from the Legs swelling by walking & subsiding when lying down x See the Londn: med: observations vol: 2 down; hence Eccymosis from a false Aneurism, Diaeresis, Contusion &c: by which the blood insinuates itself into the cellular membrane; hence also the great quantity of water evacuated from a scarification in an Anasarca. An Emphysema is a remarkable proof of the communication of these cells; this is caused by the air distending these cells & often happens from a fractured rib puncturing the Lungs by w.c the Air gets into this membrane; a remarkable instance of this happened in London, by w.c the patient swelled to that degree that his eyes could not be seen; Dr. Hunter x made a puncture at the Eye by w.c the air gushed out, & by puncturing & rubbing he was cured. Putrefaction will cause an Emphysema, from the fermentation generating air; hence hence a drowned person will after a while rise to the surface of the water. The fat contained in the adipose cells differs in different bodies; in a Foetus the fat is soft, and gelatinous; in children of a year or two old, the fat is chiefly next to skin; hence the fatness observed in children; & in adults the fat is solid and mostly internal. The cellular membrane serves for easy smooth motion, for a defence to the body, to keep the parts warm & preserve the figure of the body, & blunt acrimony. some animals we reckoned to be nourished in the Winter by their fat. Lecture 7th Of the Bones. Here we shall, 1st. describe the external conformation of the Bones, 2d. examine their internal structure, 3d. their connection, & 4th. Explain their use. A Bone is a hard fibrous compact substance. various Bones have various shapes & conformations, some are cylindrical & long, others flat, & broad, irregular &c: bones are said to be made up of Fibres forming Lamellae, fastened together by means of oblique or transverse fibres. Bones have processes and Cavities. Processes have different names from their different forms, & appearance: thus, a Condyle is an oblong process arising from the extremity of a bone; a Corone is an oblong process process terminating in a point; Spine is the sharp ridge of a Bone; Supercilia is a brim round a cavity; a protuberance is a rough process of a bone. Processes are of two kinds viz Apophysis, & Epiphysis; Apophysis is a process growing out from the body of a bone. Epiphysis is a process growing to the body of the bone, being originally separate therefrom by a different Ossification. The cavities in bones are of two kinds, one for Articulation, & the other for the lodgment of soft parts; cavities for Articulation are of three kinds, 1st. Round & deep called Catyloid, 2d. round but superficial called Glenoid, and 3d, deep & narrow called Alveoli, the Articulation of Bones is by Galen called [illegible] Joint & by him is reckoned of 2 kinds, 1st. With motion called called Diarthrosis. 2d, without motion called Synarthrosis; each of these are of 3 kinds. Diarthrosis, are. 1st: Enarthrosis, 2d: Arthrodia, 3d: Ginglymus. Synarthrosis are, 1st: Suture or Raphe, 2d: Harmonia, 3d: Gomphosis. The connection of bones is termed their Symphysis, & is of two kinds: the one wth. and the other without an intervening substance: the first is that of the Cranium by mutual Indentation. the second are of 3 kinds viz: Synchondrosis, Syneurosis & Sysarcosis. Periosteum is an elastic fine membrane, that covers the bones except at the joints teeth &c: its case is for the insertion of vessels, to strengthen the Epiphysis &c: the cylindric bones are all hollow, & so are most others & contain Marrow, the ends of the bones are cellular. F Lect. x see Edinburgh med: Essays. Lecture 8th Osteogonea. In a Foetus, the first months, there are no bones, nothing but a gelatinous fluid; then it gradually grows cartilaginous, & in time becomes boney; some imagine Bones are formed of Cartilages only by an expulsion of the redundant fluids; but Dr. Nisbet x says, & it is now general recd., that in Ossification, there is in the blood, or a fluid secreted therefrom, an ossifying juice; consisting of particles wc. are not apparent; that wherever nature designs an ossification between membranes, or a cartilage she occasions a more than ordinary afflux of fluid which distends so much the vessels wc. were before invisible as to make them capable of receiving the red globules of blood wc. is always to to be seen near to where ossification is begun. In this blood gritty particles are to be felt by the point of a knife, which have been formed by the attraction & cohesion of the particles of the ossifying juice obstructed along with the other grosser fluids in the beginning of the vessels, prepared to receive the influent juices. The membranes or cartilages some as alied between wc. or within wc. the bony particles are deposited or shoot; but without any any intermixture of the particles of the bone & cartilage, or continuation of the fibres of one substance to those of the other as is evident in bones made perfectly clean, the cartilage dropping from it as easy or easier than an acorn from its cup, & there is a smoothness of the parts of both cartilage and and Bone which show that there is no conjunction or union of the fibres of the two substances. While bones are increasing within Cartilages, the cartilages are extended & spread out, by wc., with the pressure they suffer & the great influx of various fluids, & the nutritious matter being kindred to flow freely into them, they decrease continually & at last may truly be void to be entirely destroyed. Bones digested in Acids for sometime grow flexible & gelatinous like a tendon, by which it appears the great quantity of Earth they contain makes them hard rigid. Bones are furnished with Arteries and Veins, as is evident from the drops of blood blood seen in sawing bones lengthwise, & upon their appearing tinged of a red color after the animal has eaten Madder. Dr. Havers divides the blood vessels into sanguiferous, & medullan the latter enter the bones mostly near their center in an oblique manner. Bones have Nerves as is evident from their exquisite sensibility where amputated, or exfoliated, & granules of flesh have sprouted out. Diseases of bones are 1st: a softness & rickety disposition. appearing generally from [illegible] to the 3d. year after birth, though the habit may continue thro' life. It seems to be owing to an Idiosyncrasy or a want of bony matter in the constitution. Sometimes it is said to arise from the pox & scurvy, but probably less frequent than from the other cause. We have the history of a species of Scurvy in France that affected the Bones & separated the Epiphysis. In Anson’s voyage we are told the Callus of bones wch. had been fractured & united again for may years were disposed by this Scurvy ~ Softness from a venereal Taint can be nothing more than a Caries of the bone. the disease first affecting the Periosteum & then communicating itself to ye. subject bone. As to softness from Idiosyncracy as its called; or from a particular state of the solids & fluids. Mr. Goodye furnishes us with a history of a woman whose bones without any apparent cause grew soft; her body shortened, & at last she died, & he found that he could easily cut through the limp bone & all. The academy of Paris give a more remarkable history of a woman whose bones were so soft that at length they had not solidity enough to gird the muscles action—no kind of a scorbutic or pocky taint could be observed. see Vanss 4h:423. Mr. Gooch had a case of this kind under his care, when the patient died he found the bones so soft that he split the thigh bone, the Tibia & bones of the foot the whole length very easily with his knife. Dr. Tilton of Dover relates the like Bones may likewise loose of their bulk like other parts from a loss of juices as in alveolar & vessels of old people. 2dly: Fractures. All bones have a tendency to unite again after being disjoined w:ch is effected by means of a Callus this was formerly supposed to be unorganized, but is now known to be vascular by injections & being tinged with madder. When a Callus is broke it will unite again only to the opinion of some authors. A pupil of Dr. Haller’s in a Thesis he wrote on the subject say that the Callus is first a bloody matter, then slimy, next gelatinous & then vessels from the bone & meditullium shoot out thro' it & ossifications begin directing themselves quaquavenum & thus the Callus Lecture 9th Of the Cartilages & Ligaments. Cartilages are compact, opaque, & a little elastic: of wc. there are 3 kinds, 1st: such as supply the place of bones as the Nose, Trachea Artena &c: these preserve the structure of the part & admit of motion. 2d. such as supply the place of bones before they are formed as in a Foetus. 3d. such as serve for the Articulation of bones. Cartilages differ from bones in not having Fibres nor blood vessels to be siphoned, tho’. they are imagined to be vascular; they serve at the Articulation by their smoothness to prevent abrasion; they won’t granulate nor exfoliate but may be corroded. Ligaments is compleat. sometimes the bones won’t unite but with great difficulty. 3dly: Caries. A caries in alone is similar to an ulcer in the flesh it has circulation but it is unsound & often shoots out irregularly as the fungus of an ulcer See more so in med:[illegible] 2:h:k0 [illegible] [4?377]. 4thly: Spina ventosa – this is a caries beginning on the inside of the bone & affecting it clear thro', hence Surgeons bow into the bone to let out the matter, but in general the limb is to be taken off. See Van Swieten 4 p 377 A node by some is said to be an Exostosis of the bone, but for the most part if not always it begins in the Periosteum. should be open'd before it affects the bone 5ly: Anchylosis is a stiff joint having little or no motion. from the bones running into each other & the cartilages being eroded. Van swieten vol 4 p 457 gives several curious cases of Anchylosis of all the joints in the Body. See also Le Bran’s Surgery. x where it covers the Cartilage. it is calld. Perichondrium the external lamina of the capsular ligament goes from the substance of one bone to the other over the articulation & is inserted beyond the Epiphysis &: Friction 6th. Exostosis is a tumefaction of a Bone or an excrescence growing out of the bone. It may proceed from a redundancy of ossifying particles in the system or in the part only from a morbid cause see Van swieten 4 p 424. See the case of 9: Scott of the Pennsylvania Hospital in my Adversar: med: See Cheselden p 5. Ligaments are firm, compact, unelastic, membranes; serving to connect the joints, prevent luxation &c: The Ligament, Bones, Cartilages, Tendons & Dura Mater are now reckoned none of them to have much sensibility in a natural state. v: Whytt & Haller The capsular ligaments are very strong & compact, & made up of hard Lamella, the inner lamella being a reflected membrane going over the head of the joint. cover the Cartilage x & so coming to join the external lamella, which is firmly inserted near the joint. These capsular ligaments forming a sac in wc. is contained, a mucilaginous liquor serving to lubricate the joint: for for in all Joints; for motion there are synovial glands which discharge the above synovia, this is subject to be disordered: 1st. to become thin & Icorous, 2d thick and inspissated &c: It is generally received of late, that the capsular ligament is lacerated in a Luxation of a joint unless from internal cause, or a relaxation; & violent extension is unnecessary in reduction of the same; no more being necessary than to bring the ends even, and then coax them into their proper places, & there keep them by proper dressings & bandage. For as particular description of the Bones vide Monro’s Osteology, and of the muscles Douglas’s Myographia Lect. 40th: In the Osteology we divided the body into three parts, viz: Head, Trunk, and Extremities; the Trunk of the Skeleton we subdivided into, the spine, Thorax, and Pelvis, but in a fresh subject we divide the Trunk differently, viz: into The Thorax, and Abdomen, or upper, & lower belly. The Viscera of the Thorax are only the Heart, and Lungs, & therefore not necessary to be subdivided. The Abdomen is separated from the Thorax by the Diaphragm. The Abdomen by reason of its largeness and the many Viscera contained therein, has been divided into several parts, by imaginary lines, for the readier knowing the particular situation of each Viscus. The divisions are as follows, 1st G 1st. That which lies under the Cartilage Xyphoides, is called Scrobiculus Cordis, 2d. From the Scrobiculus Cordis down to within 2 or 3 inches of the Umbilicus is called Regio Epigastrium, circumscribed, and on each side there of it is called Regio Hypochondrium. 3d. From the Regio Epigastrium to 2 or 3 fingers below the Umbilicus is called Regio Umbilicus, circumscribed, and each side Regio Lumborum, 4th. From the Umbilical Region to the Os Pubis is called Regio Hypogastrium, and on each side the Regio Hiaea 5th. The lowest part is called the Regio Pubis. As we are sometimes called to open the body of a deceased person before their friends, particularly if they died of a violent death; we should endeavor to to do it with regularity & decency. The antients opened the Abdomen by beginning at the Sternum & directing the knife along the False Ribs to the Loins, then along the spine of the Ilium to the Os Pubis; and laying the loose part over on the contrary side. Others begin at the Xephoid Cartilage & make a straight incision down to the Umbilicus, then dividing the incision directing one to the spine of the right, & the other to the spine of the left Ilium, and turning each part back. But the best method is to begin the incision at the Xephoid Cartilage and going straight down to the Olsa Pubis and then another transverse from the Navel to the Loins each way. The Thorax is opened by pushing off the Teguments & Cutting the Cartilages by the Sternum. Lect. All the internal superficies of the cavity of the Thorax, the ribs, cartilages of the ribs & convex side of the Diaphragm except where the pericardium lies in contact wth. it are lined with one continued, thin, nervous, very strong membrane, internally very smooth called Pleura. On the external superficies of this every where is the cellular membrane wc. in very fat animals is often so enlarged with fat as to lessen the capacity of the Thorax & these cause a shortness of breath. The Pleura when it gets round to the vertebra elevates itself perpendicularly lowd. frenum wc. with the one on the other side from a doable pleura called Mediastinum dorsale. The same duplication is made of the Sternum when it is called mediastinum pectorale. The pleura likewise covers all the muscular circumference of the diaphragm above the cellular membrane wc. arising up together with the orb of the septum from the back sternum, from the external membrane of the pericardium wc. is the third cavity of the Thorax in the middle between the 2 cavities of the pleura containing the Lungs & formed a conjunction of them This membrane of the pericardium is lined internally with a thin membrane wc. is a branch of the external membrane of the Heart. The great vessels from the Heart as they pass thro' the pericardium & go on beyond it or move also at above the cellular one from the external membrane of the pericardium. this membrane forming about to the pulmonary arteries & using wc. when they arise at the Lungs is expanded out & forms the extenal coat of the Lungs. Kaan de Perspi Hippocrat. Lect. 41st: Of the Pleura. The Pleura is a fine membrane, which lines all the cavity of the Thorax and is reflected back over the Lungs. There are two Pleura one on each side, like two bladders beginning as we may suppose at the sternum and going round within the Ribs to the Vertebra of the Back, then reflected back upon the outside of the Lung (making the coat of the Lungs) to the sternum; there running in or uniting with the first Fibres of the same and so on the other side; where the two Pleura meet at the sternum; they are not quite in contact with each other, but there is a small space left between which is filled up with cellular Membrane. Of Constat pulmo duplici vasorum genere, aerifero scilict & sanguifero. Aerifera omnia vasa ortum ducunt ex una trachea, quo mox a faucibus intitium capiens, ante oesophagum, descendit, thoracem post thymum intiat; post cavem descendentem & pericardii apicem, as quartam thoracis vertebram, qua est a superiore una tertia pars ipsius pulmonum longitusinis divaricatur. Hujus dein crura tendunt ad utrumque pulmonem, & statim dividuntur, in homine dextrum in tres, sinistrum in binos ramos, qui tune bronchia dicuntur, as totidem pulmonum lobos, quos ubi ingressa funt, disperguntur statim in ramos minores, & minores; qui omnes ad obtusum angulum, respectutrancorum, oviuntur. Remi autum majors ingressi pulmones, pro maxime parte, descendunt, pauci recti procedunt, ubi ingrediuntur; aliivero adscendunt aeriferorum truncorum, & horum ingressum est. quod prater Eustachium meminen observasse video. Ultimi Of the Lungs. The Lungs are Vascular Substances composed chiefly of Air Vessels, and Blood Vessels; the Air Vessels are Ramifications of the Trachea Arteria, and are called Bronchia; the blood Vessels are ramifications of the Vena and Arteria Pulmonalis; beside-which they have an Artery wc. serves to nourish them, called the Bronchial Artery coming from the Ascending Aorta together with Nerves and Lymphatics, and some say also Parenchyma which is perhaps no more than cellular Membrane. Some Anatomists suppose there are little follicles or cells at the extremity of the small Bronchial Vessels, which if there is are not discernable. Ultimi autem ramuli ommitunt cartilagineam indolem, & expanduntur in vesiculas oblongas, membranaceas, cavas, qua Malpighiana dicuntur, ox quibus fiunt area, & lobuli, qui tandem pulmonum lobos efficiunt. Comitantur aerifera hac vasa, in omni decurser, ad vesiculas usque, vasa Sanguifera, qua omnia oriuntur ex arteria pulmonali, qua cordis dextro ventriculs egressa, qua parte superiore ventriculs sinistro jungitur, adscendit, mox se incurrat, arcum facit, & sub aorta decumit. Descendit The inside of the Trachea arteria is lined with a membrane in which are small glands that secrete mucus for lubricating the its internal surfaces; in cold, this means is sucked into great quantity—sometimes inspissated is spit up very thick especially in the morning. Dissection has taught us that this membrane is the seat of that disease in children called the Hives & is found separated from the cartilages – nothing proves so useful in this disease as large doses of 8. I have known 10 g of calom: given to a child 2 years old produced 2 copious stools & disease immediately vanished The Lungs are divided into two Lobes, by means of the Mediastinum and Heart. The right Lobe is divided into three Lobuli by fissures; and the left Lobe is divided into two Lobuli. In a natural state, the Lungs are every were in contact with the Ribs, so that there is no vacuity left. The Trachea Arteria is composed of cartilaginous Rings, which behind are not quite shut but a small membrane between; each of the cartilages are connected likewise by membranes. The Lungs are liable to inflammation, and Ulceration. In inflammation of the Lungs we should use plentiful bleeding, oiluants, fomentations externally and the steams of warm liquors particularly Vinegar, into the Lungs thro' the mouth. x The ventricles are divided by a middle partition called Septum Cordis. Lect. 42d: Of the Hearts. The Heart is a strong muscular substance, situated obliquely to the left side, more than the right; part of the inferior and or Apex in contact with the Diaphragm, and pointing between the sixth and seventh Ribs on the left side; the Apex being likewise nigher the sternum than the Basis. The Heart is the Origin of the Veins and Arteries. There are four cavities in the Heart, two Auricles, and two Ventricles; x one right and one left, at the right Auricle the Vena Cava enters, and at the left: the Vena Pulmonalis; at the right Ventricle the Arteria Pulmonalis egresses, and the Aorta from the left. M x these cordae Tendineae arise from the Carnae Columnae. At the entrance of the Vena Cava into the right Auricle of the Heart are three Valves called Valvula nobilis, and about the middle of the Auricle there is a little knob called Carna Sesamoidea: At the entrance out of the right Auricle into the right Ventricle and two valves called Valvulae bicuspides, connected by sou:e small tendinous cords called Cordae Tendineae x; the internal part of this Ventricle is rough & muscular having many muscular Pillars, called Carnae Columnae which serves for to strengthen the motion of the Heart and to work the blood so as to prevent its concretion & forming Polypuses,- which however sometimes happens. After the blood has passed out of the right Ventricle into the pulmonary Artery it is prevented from returning by three valves Valves named Valvulae Semilunares. There are likewise Valves at the entrance between the left Auricle and Ventricle named Valvulae Mitrales fastened by the final Cordae Tendineaes on the left side of the Heart. The left Ventricle is larger and a stronger & much thicker muscular bag than the right Ventricle, its internal part tougher and the Carnae Columnae bigger. As the entrance out of the left Ventricle into the Aorta are likewise three Semilunar Valves. The Heart is contained in a strong Membranous bag called Pericardium the internal part of which bag is very smooth and lubricated with a juice that continually transudes through the same H. Same Dr. Plott in his History of Staffordshire attests of his own knowledge the case of one Mary Eagle who drew two quarts of milk from her breasts every day besides what her child sucked and that she could make two pounds of butter every week ever since she was brought to bed which was above five months when the Dr. saw her. Borellus in his Hist: & Absence: physioc-med: related an instance of the like native in one Mary Caron a Taylor’s wife of Bologna who afforded milk enough for two children & made Butter besides Biog Dictionary Led: Esq: Lect. 43d: Of the Diaphragm The Diaphragm is a large Muscle between the Thorax and Abdomen, the muscular fibres of which arise from the internal part of all the ribs below the sternum, and from the lower end of the sternum, these fibres terminate in a tendinous expansion which is nearly in the middle of the Diaphragm, and which is of an oblong figure coming very nigh the sternum upon which part the Apex of the Heart lies, and from thence turning down towards the Angle of the Ribs and is called the oval tendon of the Diaphragm the lower part of the Diaphragm is likewise muscular and on each side of the Vertebra are muscular Fibres sent Sent down some distance called the Crura of the Diaphragm, these terminate near the Origin of the Psoas muscles which arise at the internal part of the Vertebra of the Loins and pass out of the Abdomen at the Inguen to be inserted into the Os Femoris. it is by making way through these muscles that Abscesses of the Loins sometimes fall down to the Thigh and are opened and discharge their contents there. There a three Apertures thro' the Diaphragm, one of the right side of the Vertebra through which the Vena Cava goes, a second contiguous to the Vertebra inclining a little to the left thro' wc. goes the Aorta, a third over the Aorta & exactly over the Vertebrae through wc. the Oesophagus goes. Of Lecture 44th: Of Respiration Respiration is an alternate dilatation and contraction of the Thorax the former performed by Inspiration and the latter by Expiration. The parts subservient to Respiration are divided into Active and Passive The active parts are the Ribs, Sternum, Heart &c: acting upon the the passive which are the Lungs themselves. The dilatation of the Thorax happens both in length and diameter; in length by means of the Lungs pressing upon the Diaphragm and thereby rendering its convexity more plane, the diameter is increased by the motion of the intercostal muscles &c: Thus the capacity Capacity of the Thorax is increased and as there is no vacuum between the Lungs and ribs allowed of in a natural state, the capacity of the Lungs will also be increased and there will be a vacuity in the Lungs wc. nature not admitting of and by the pressure of the Atmosphere rushing through the Aspera Arteria they are soon filled with Air making Inspiration. The fresh Air that is drawn in by Inspiration stretching the Bronchiae and stimulating the same cause them to contract and expel the Air making Expiration, some Authors imagine these are small Muscles between Between the cartilaginous Rings of the Bronchiae which they call Musculi Mesenchrondroeci serving to contract the the same in Expiration. The uses of Respiration are four, 1st For the circulation of the Blood, thus in Inspiration the Lungs are distended and the fine contorsions of the Arteries are are elongated so as to allow, blood to pass through them whereas in a collapsed state the blood cannot pass through them. in Expiration the Lungs collapsing push the Blood through the Veins into the left Auricle of the Heart. 2d. For sanguification by communicating the Blood making it more florid & denser 3. For cooling the blood 4th. For Vocification, exclusion of [illegible] &c: Of the Peritoneum This membrane is similar to the pleura, being smooth on one side & connected by cellular membrane on the other; it is reflected from the contained path to the containing. It makes a compleat bag 1st: covering the viscera by intimate connection, & then covering the abdominal muscles loosely on the inside. The peritoneum has been considered as a double membrane true or false, the last is no more than cellular membrane wch. connects the peritoneum to the external parts. We may conceive that all the viscera are behind or without the peritoneum, wch. running up on one side of a viscus is reflected back on another so as to form an almost compleat cover to each viscus separately, so that by a very nice dissection the peritoneum may be taken out in a compleat bladder having no perforation at all, leaving all the viscera undisturbed. Lecture 45th: Of the Stomach The stomach is a large muscular bag situate Obliquely from the Left Hypochondrium to the Epigastrium and serves for the reception of our food & digestion of the same, it has an upper & lower curvature called the lesser and greater curvatures of the stomach. There are two Orifices to the stomach; the superior one called the Cardia which enters it from the Oesophagus don't open at the fundus of the same but obliquely, at the side an inch or more from the end. Towards the inferior end the stomach grows smaller & turns up opening into the Duodenum by an Orifice called the Pylorus where there is J The Nerves of the stomach come from the par vagum. Is a partial kind of a valve which does not prevent the regurgitation of fluids into the stomach being only a thickness of the internal coat of the stomach. The stomach is furnished with Nerves and blood vessels. x Some Anatomists say there are small glands in the stomach, but if so they are not easily discovered, there is however a fluid discharged into the stomach from the extremities of the Arteries called the Gastric lymph from the gastros the Greek name for the stomach, there is likewise Lymphatics which absorb the redundant fluids & carrys it into the blood. The coats of the Stomach are three 1st. coming from the peritoneum and is called called the Peritoneal Coat. 2d. Muscular being composed of thin muscular fibres running longitudinal and transversely by which the capacity of the stomach is decreased the readier, to expel its contents. & 3d: Villous or internal Coat which is thin. Of the Intestines The first Intestine next the stomach is the Duodenum beginning at the Pylorus and ascending two or three Inches, has then two or three inflections pulsing down & across the Vertebrae — being all the way tied fast by a duplicature of the Peritoneum to the back, having no mesentery. The Ductus Choledocus & ductus Pancreaticus both enter the Duodenum several Several inches from the Pylorus, not both by one Orifice but by two very near together, next the Duodenum is the Jejunum, & then the Ilium which is the last of the small instestines. The coats of the Intestines are three the same as the Stomach, and in the small intestines are anular duplicatures of the internal Villous coat forming what is called Valvulae Coniventes which serve for two purposes, first to make the passage rough & prevent the Faeces, from passing on too fast and secondly to give more capacious origin. to the Lacteals The Ilium enters the Caecum not at the end but about an Inch there from obliquely the blind end only being Being called Caecum, where there is an appendage called Apendicula Vermiformis. At the entrance of the Ilium into the great Intestines, there is a Valve formed by the inner coat of the Colon & called Valvula Colli which in a sound state entirely prevents the regurgitation of the Faeces or any fluids passing, injected per Anum. The Colon runs up the right side then along under the stomach and down the left side, surrounding all the Abdomen, hence Clysters beside discharging the Faeces serve the purpose of a fomentation to the contents of the Abdomen. The Intestines are furnished with blood vessels from the two mesenteries except except the Rectum which receives its from the Hemorrhoidals. The Mesentery is a double membrane formed by a duplicature of the Peritoneum serving to connect the Intestines. & through which which the blood vessels go to be distributed to the Intestines, through it likewise goes the Lacteals which are fine Lymphatic or absorbent vessels arising from the villous coat of the Intestines and passing through the mesentery, they terminate in the Receptaculum Chyli, to be described hereafter, there is also a great number of Glands in the Mesentery through which the Chyle passes, and by which it is supposed to receive some alteration. These glands are very small. Lect. 46th Of the Lacteals & Thoracic Duct The Lacteals are an innumerable number of small vessels arising as before said from the villous coat of the Intestines & running through the mesentery in the duplicature of the same and through many fine glands and terminate in the Thoracic Duct serving to convey the Chyle The Thoracic Duct is a small canal running up the Vertebra of the Spine between the Aorta & Vena Azygos and under the Vena Cava until it gets above the Heart then it turns a little to the left and ascending empties itself in to the subclavian Vein. The lowest end of this Duct has been called Receptaculum Chyli but improperly as its no larger than the rest of the Duct neither do all the Lacteals enter there, but some higher Of Digestion Digestion is that change of the Aliments whereby they are filled for the nourishments of the body, this is different from the different juices mixed therewith and in the different parts of the body. The first change that happens to the Aliments is in the mouth by means of Mastication and mixing with the Saliva by which it is somewhat dissolved and fitted for more easy Deglutition Saliva is a clear mucous transparent fluid secreted by the Glands of the Mouth in the great plenty, and is of great use in digestion. After the Aliments is sufficiently masticated & mixed with the Saliva they are by the Tongue pressing against the roof of the Mouth forced into the Pharynx Pharynx and from thence through the Oesophagus into the Stomach. The Muscles employed in this act of deglutition are very many, serving chiefly to pull up the Oesophagus and to press the food down through the same, and we may very well conceive of the act of Deglutition by that of drawing a stocking on the Leg, part of the muscles drawing up the Oesophagus as we draw up a stocking upon the leg, and the rest pushing down its contents as we push down our leg into a stocking. The manner in which our food is digested in the stomach was by some of the Antients reckoned to proceed from heat K Heat, others reckoned it was performed by means of trituration, and others again from the different juices there mixed imagined it was performed by Fermentation, but modern Physiologists from many observations, think it is performed by all three jointly viz: Heat, friction and Fermentation. After the Aliments are sufficiently digested in the stomach, by the contraction thereof which is the beginning of the peristaltic motion of the Intestines, they are forced through the Pylorus into the Duodenum, where it continues some time and receives another change by having the Bile and pancreatic juices mixed therewith. The The Bile is an oily bitter, and attenuating substance endued also with a saponaceous virtue it will incorporate with Oils and when so mixed they are both soluble in water, it unites with salt forming a green color. by which it appears that the Bile is of great— use in attenuating the viscid part of the Aliments, and stimulating the— Intestines, the latter we are assured— of by this that Bile secreted and— discharged into the Intestines in too great a quantity causes a Diarrehea, and in a Jaundice where the Bile returns into the Blood and is not sent into the Intestines a Costiveness happens with while stools, and Boerhaave says Says the Gall of Animals is of use in this case to supply the want of Gall DeGraaf collected great quantities of the Pancreatic juice from Animals which he says is subacid it is reckoned to be somewhat of the nature of the Saliva, some reckoned it serves to sheath the Acrimony of the Bile but this in a natural state is not too Aerid These two fluids being mixed with the Aliments in the Duodenum the fluid and nutritious particles of the same are absorbed by the Lacteal vessels and by them carried into the Thoracic Duct to be conveyed into the Blood. These Lacteals are in all the intestines, but in the small ones in the Greatest Greatest plenty, That there are also Lacteals in the Colon seems evident 1st. From the rout the colon makes round the Abdomen, for if that is not for absorbing the particles that may chance to be not taken up by the vessels in the small Intestines why did it not go out strait like the Rectum and immediately terminate in Ans? 2. From persons being known to have lived a long time by Glysters, not being able to get any thing thro' the Oesophasgus, & it is known that they cannot pass by the Valve of the Colon. The contents of the Intestines are carried along by the Peristaltic motion thereof thereof. Vomiting is an inversion of the peristaltic motion and is performed by means of a deep inspiration which presses the Diaphragm against the stomach & a convulsive contraction of the stomach by which its contents are thrown up hence we learn that Emetics are good in Fluxes by inverting the peristaltic motion they stop the same. Of the Bile Bile is secreted in the Liver. It is 8 times as viscid as water. More subject to concrete than any other humour in the body. Its specific gravity to water is as 010 to 795. In a such quadrupeds & in the human species the bile is very bitter, but most so in carnivorous animals. Recent bile easily mixess with water. It mixes with oil by triture. Mixed with water it partakes of the property of Soap, dissolves oil so that it will mix with water & takes out grease spots. It dissolves resins & mixes with balsams. It dissolves Myrrh Bdellium & Wax like the yolk of an Egg, & is supposed to dissolve the Blood when mixed with it as in a Jaundice. The Ductus Choledochus may may be compressed & stopped by the Duodenum being distended with flatus. Eating Mushrooms has been known to distend the duodenum greatly & trangulate the ductus choledocus as it were with a ligature. It may also be obstructed by the contractions of the fibres of the intestine from stimuli as happens in the Colica pictonum, biliosa, inflammation of the duodenum, acrid purges, glass of Antimony & poisons. Hither we may refer the Jaundice in Infants which is removed by Rhubarb. Storck has seen the ductus choledochus obstructed with a cheesy coagulum. Hillary says this is frequent in the warm Islands. See Monro Ed: Ess: v. p 247 Baglivi prax: med: Haller tom: 6. p 590 x about 4 fingers breadth below the pylorus. Lect. 47th Of the Liver The Liver is a large Viscus situated immediately under the diaphragm mostly in the right Hypochondrium extending over the Stomach into the Epigastrium it is convex above and concave below suspended by three Ligaments one above to the Diaphragm one broad on the upper part of the round ligament from the Umbilicus which was the Umbilical Vessel in a foetus state. There are several fissures in the Liver 1st. Divide the great lobe from the lesser one. 2d. divides the Lobulee spigeli & the third where the Hepatic Vessels enter; The Vesica Fellis lies in a depness in between the two lobes of the Liver from where goes a duct remarkably contorted to appearance about two inches when it joins the hepatic duct, both of them united form the Ductus comunis Cholidochus which terminates in the Duodenum. x The Coat of the Liver comes from the L x sometimes called Tunica Glissoniana *The hepatic Artery divides a little before it enters the Liver one branch going to one lobe & the other to the other Lobe; it serves to nourish the liver & is said to secrete a small part of the Bile, some few of its evanescent frame has terminating in the pori biliarii as is proved by injections. The Peritoneum x beside which some Authors describe another coat wc. is scarce to be seen, The Gall Bladder has three coats 1st. from the Peritoneum, 2d: Muscular & The 3d. Villous, appearing like a honey comb inside. The Liver is furnished with Veins Arteries & Nerves. The Blood Vessels are the Hepatic * Artery & Veins & the Vena Porta. The Vena Porta is like an Artery first in its Office & 2dly. in the thickness of its coats; it arises from all the Viscera of the Abdomen terminating in the Liver and is supposed to carry the blood for the secretion of the bile, 1st. From the longness thereof & the smallness of the hepatic Artery. 2dly: By injections passing from it into the biliary Duets &c: It is certain however that the blood being carried into the Liver, part of it is converted x The general opinion of the ancient Anatomists was that the bile was conveyed into the Gall Bladder by little ducts running from the liver immediately into the bladder which they called ducti hepaticistics. Pechlin was the first who denied the existence of these ducts in the human body, then Ruysch, Cowper, Bidlow, Berger, Morgagni, Heister, Ludwig, Carsons, Lieutaud, Ceyer, & Cheselden. who says if a ligature be applied round the cystic duct, or if it be obstructed the gall bladder does not become turgid. Bohnius emptied the gall bladder of bile then tied a ligature round the cystic duct & upon examining the same several days afterwards found no bile in the cyst itself but the part of the duct between the ligature & liver was greatly distended. Bianchus & Haller have done the same. This clearly proves that there is no communication between the Liver & Gall bladder but by the cystic duct. What was supposed to be Hepatocystic ducts is demonstrated to be only blood vessels by Ruysch, Guntz, Haller Morgagni & others. converted into Bile & carried by the pori Biliarii which all meeting together form the hepatic duct though the hepatic duct to the cystic then regurgitates into the Gall Bladder; that the Bile regurgitates thus x into the reservoir is proved 1st. by there being no other passage though some supposed there was by little ducts wc. they called cysto hepatic ducts, but there is no such is evident from the injections not passing through that way into the Cyst, & in a Viper the Gall Bladder is vitiate some distance from the Liver. Horses & Deer have no Gall Bladder. That the Bile goes through the hepatic Cystic Ducts into the Gall Bladder is proved 2dly: by blowing into the hepatic duct the wind passes free into the cystic than through the ductus cholodochus. The remainder of the Blood is received by the Veins & carried back to the Heart Diseases x more frequently if not always the Jaundice arises from an obstruction of the Ductus communis Cholidocus An obstruction of the cystic duct alone will not occasion a Jaundice. Diseases of the Liver are: 1st. Hydatides these are of two sorts the first tumors composed of several lesser cysts filled with a gelatinous matter, the other a kind of vascular Cysts, the fluid circulating through it. 2d. Inflammation this is best relieved by plentiful bleeding warm relaxing and stimulating applications &c: It sometimes suppurates & even grows cancerous. 3d Scirrhi like other Glandular parts 4th. It gives origin to the Jaundice wc. proceeds from an obstruction in the Cystic x duct by wc. means the Bile is prevented from going into the Gall bladder and therefore returns into the Liver where it is absorbed by the Veins or lymphatic Vessels & carried into the blood & by that means tinges the shin, the cystic duct may be stopped by concretions tumors compressing the The same or more commonly by means of a stone lodged therein: a stone or concretion is best removed by Vomits which agitating the parts serves to remove it or by friction stimulating the same. Some have imagined that a Jaundice proceeds from a scirrhus Liver, but this is proved to not be the cause as no Jaundice can be unless the bile is absorbed after it is perfectly made Transient Jaundices sometimes happens to Children from a spasm of the Duodenum from acidities or otherwise hinders the Bile from passing therein & which is relieved as soon as the spasm is removed. Durable Jaundices happen when the Obstruction of the Cistic duct cannot be removed Lect. 40th: Pancreas is a long slender conglomerate Gland situate obliquely under the stomach between the spleen & Duodenum. each little x Haller supposes the pancreas secretes three times as much fluid as the salival Glands. * a costiveness and a pain in the region where this gland is seated is the common symptoms of its being obstructed. little acini or knot supposed to be the extremity of an Artery wound up in a knot and the whole vascular like the liver and all the other Glands of the body. from each acini goes a small excretion Duct which terminates in a larger duct in the middle of the Pancreas & called the pancreatic Duct & through which the pancreatic juice flows into the duodenum, the glands of the pancreas being the same with those that discharge the Saliva are supposed to secrete the same juice and for the same Use. x Diseases of the Pancreas are Inflammation, Cancer, & Schirri, which * are very difficult to be known until past cure they are however removed much in the same same manner as the same Diseases on other parts, Soap is a very good thing in this case which not only seen x This appears very reasonable though it was never taken notice of by any author before Mr. Monro. Is a good resolvent but supplies the place of this juice in digestion. Sometimes a Diarrhea happens in a Salivation and proceeds from a too great a secretion of the pancreatic juice which being the same with that of the saliva is supposed to be effected in the same manner with Mercury & is only to be removed by removing the cause. x Omentum is a fatty double membrane composed or formed by a duplicature of of the Peritoneum it has an appendage between the Liver & stomach called the Omentum minor & may be inflated. Uses of the Omentum are to lubricate & keep the Intestines warm, and it is supposed to supply oily particles to the Bile and also the blood. It is sometimes much distended with Fat and in very lean subjects quite reticular. Spleen Of the Spleen The Spleen is a roundish lobulated Gland situated in the left Hypochondrium it is furnished with blood Vessels and but very few Nerves. The Antients supposed its use was to counterbalance the Liver, others thought it contained a fluid called the Atrabilis, but the moderns mostly think that it is subservient to the Liver, it has been taken out of several animals without any apparent damage and is not therefore a vital viscera. It is subject to very few diseases, scarce ever being inflamed schirrius or cancerated, by reason of the fewness of the nerves, its only subject to a viscidity of its fluid and an enlargement therefrom. Lect. x The arteries generally divide into three branches and the vein into two before they enter the Kidneys. Lect. 49th Of the Kidneys The Kidneys are two Glandular bodies situate between the false ribs & Ilium. the situation of the right Kidney is somewhat lower than that of the left oweing to the Liver being on that side. The blood vessels of the Kidneys are an Artery and a Vein called Renales or Emulgents the right emulgent Artery is longer than the left & the left Vein than the right. These vessels enter at the Pelvis and are distributed through the same. x The external part of the Kidney is called Cortical the thickness of which is irregular and in this the Urine is secreted and emptied into little ducts in the inner part M x the pelvis is an enlargement or expansion of the of the upper part of the ureter where it enters the Kidney or rather where the united urinary Tubes regress out of it. part of the same, which is called the Mamillary part of the Kidneys. The little ducts into which the Urine is secreted are called Tubuli Urinarii and are in number about a dozen, these all unite in the Pelvis x forming the Ureter which is a membranous canal conveying the Urine from the Kidneys to the Vesica Urinaria. The Ureter as it enters the Pelvis of the Kidney divides into three parts one going towards each end and the other through the middle. The coats of the Kidneys are two, the first called Adipose and the second Membranaceous. There is an appendage to the Kidney called Glandula Renales or Gland Glandula Succentriari situate at the top of the Kidneys its particular use not known but supposed to be subservient to the Kidneys. Diseases of the Kidneys are, Inflammation, Diabetes from a too great laxness of the Vessels allowing the red particles of the blood to pass through them, gravel, Scirrhi &c: Lect. 50th: Of the Bladder The Bladder is a membraneous Bag situate in the Pelvis the upper part of which is covered with the Peritoneum but when it is very much distended it protrudes about an Inch above the Pelvis & being there covered with the Peritoneum Peritoneum & in this place is the upper Operation for the Stone performed by making an Incision into the Bladder without cutting the peritoneum the doing which would be of dangerous consequence. The coats of the Bladder are three, 1st: the common coat 2d: muscular and 3d: Villous, the muscular coat at the neck of the Bladder is thick & circular and is called Sphincter. The Ureters enter the Bladder one on each side about an Inch from the neck thereof by a small Orifice obliquely. The situation of the Bladder is between the Rectum & Olsa Pubis in men and between the Uterus & Pubis in women its use is a Reservoir to the Urine Parts of Generation Lect 51st 1st In a Male. These are the spermatic Cord, Testes Scrotum, Vesica Seminales, Prostate Gland, and Penis. The spermatic cord is composed of the spermatic Artery and Vein, Nerves, Lymphatics, & Vas deferens all included in acellular coat and some have supposed a muscular wc. they called Cremaster wc. is not visible except where it passes out of the Abdomen wc. it does in an oblique manner through the rings of the Abdomen, by which the Intestines and Omentum sometimes falls thro' forming an Herniae Inguinalis or Jerotalis along the side of the spermatic Cord The x Caput Gallinaginis The vas deferens empty themselves somewhat like the biliary ducts there being a passage from them immediately into the Urethra, but it commonly regurgitates into the Vesicula Seminales & there kept till used. Vesicula Seminales are two Glands situate under the neck of the Bladder, composed of little cells which communicate with each each other, being reservoirs for the semen, from each of these there goes a small duct which opens into the Urethra at the Caput Galaginis, x where is a large Gland called the Prostate Gland which secretes a fine mucus to defend the Urethra from the acrimony of the Urine. The Scrotum is composed of skin Cellular Membrane &c: next to which has been reckoned a muscle called the Dartos which is not to be discerned discerned, and the first obvious Coat is that wc. surrounds the Testicle much as the Pleura or Peritoneum does the contents within them this is called the Tunica Vaginalis propria Testes, and within that is a coat which adheres to the substance of the Testicle called the Tunica Albuginea, The substance of the Testicle is wholly Glandular, the spermatic Artery entering in at the side of the same and distributed through the same terminating in fine secretory ducts and these again in excretory ducts which uniting into one form the Vas deferens, The Epididymus is an Appendage to the Testicle formed by numerous convolutions of the excretory duct, reckoned 6 times as long as the Spermatic Cord. Lect. 52d: Parts of Generation in Females. These are either external or internal, the external are the Mons Veneris on which hair grows at a certain age Labia or External Lips of the Orifice at the upper part of wc. is a small body called the Clitoris under which in a small groove is the Iter ad Urinam thro' which the urine passes & into which the Catheter must be introduced in a suppression of Urine, & we should be well acquainted with this Orifice as the modesty of women often denies us a sight of the part, so that we must introduce the Catheter by feeling, at the lower part where the Labia unite is formed a Fraenum or Fushet or Foushette. x Iter externum ad Uterum Nymphae are two spongy bodies within the Labia within these in Virgins is a circular membrane called Hymen within these is the Iter externum ad Uterum x Vagina is a membranous substance furnished with rugae by wc. the Penis is more titillated in Coitus, there is likewise many small glands in the Vagina wc. secrete a liquor to lubricate the same and during the Venereal orgasm whether real or imaginary there is sometimes so much mucus secreted by these glands that it has been discharged, in great quantities so as to wet all the external parts, this by some is reckoned the Female semen. At the bottom of the Vagina is the Iter internum ad Uterum, the Os Uteri or Os Tincae. N Between x or young Puppy Between the Fushet and Anus, there is a seam called Perinaeum, this in difficult deliveries is sometimes lacerated by the largeness of the Foetus & it is necessary to prevent this accident for to support the Perinaeum with the hand while the Foetus advances Uterus is a small body situate obliquely between the Bladder & Rectum its coats size near half an Inch thick & its internal cavity very small; the Neck of the Uterus is full of rugae wc. serve to allow the same to dilate for the expulsion of the Foetus. The Os Tincae resembles the mouth of a Tench x situate at the bottom of the Vagina tho' not a continuation thereof the Vagina being inserted x An demande si le corps de la matrice etant renverse, & ayant tente inutiliment va induction, elle montroit quilque disposition a ve gangrener, e il conviendroit pour lors de l’eactirper, apris avoir porte une ligature le plus haut qu’il veroit possible. En parsil cas on ne devroit point balancer de faire cette operation pour empecker que la gangrene faisant du progres du cote des parties interieures, elle ne causat la mort a la malade. L'extirpation de la matrice, quoique rare, never sit point en cette occasion une operation temeraire, son succes etant prour a par plusieurs observations Verdeer's Anal: v: 22 p 66 Rousset, dans son Traite de Partes Caesares, dit qu'une femme a la suite de pluesieurs accouchemens laborieux, eut une precipitation de matrice qui ne pouvant etre inserted round the Os Tincae. From the Fundus of the Uterus there goes off nearly transversely on each side, a tube called the Fallopian Tubes lying loose & growing larger toward the further end wc. is fimbricated. The Uterus is suspended by the ligament lata & rotunda x Ovaria are two glandular bodies situate on each side of the Uterus inclosed in cellular membrane in each of these Ovaria are near 20 small Ova Of Generation This is perfomed per Coitus by the Male’s introducing his Penis into the Vagina, & perhaps into the Os Uteri tho' this is denied by some at which time the parts grow turgid by the venereal Orgasm the Os Tincae opens & receives the male Semen in which are Anamalcules, immediately attended. reduite, se gangrena, & tomba d’elle-meme. La femme ne daigna pas garder le lit, & elle Jouit d’une parfaite vante’ pendant trois ans, au bout desquels, etant morte d'uno fievre continue, louverture de fon corps fid voir que c’ etoit veritablement le corps de la matrice, qui par pourriture s’etoit s’epare de lui-meme Ibidem p168. afterwards the Os Tinca closes During the Orgasm the fallopian Tubes grow erect & the Timbria seize the Ovaria at wc. time some one or more of the Animalcule ascend through the Fallopian Tubes & enter the first ripe Ovum wc. has now burst the cellular membrane by its turgidity, then the Ovum is disengaged & carried by the Fallopian Tube into the Uterus, and the place where the Ovum was in the Ovarium is soon after filled up by a yellowish substance called Corpus Luteum, this I proved by opening a Bitch in the Hornes of the Uterus were 7 whelps in one three & the other four & in the Ovaria were the same number of Corpora Lutea, by alike experiment upon a Bitch opened while the Dog was fastened thereto, for dogs have no Vesicula Feminalis are obliged to remain fastened to the Bitch a a long time while the Semen is excreted and carried from the Testes by the Vas deferens into the Uterus I found that the semen was ejected immediately into the Uterus. Though the preceeding Hypothesis seems incredible and almost impossible, yet it answers all the Phenomena of Generation the best of any system yet advanced: however the subject is extremely intricate & no doubt is one of the Arcana natura which the omniscient Jehovah of his infinite goodness sees fit to hide from us. Lect: 53d. Of the Foetus its Nutrition &c. The Ovum of the female wc. is foecundated in the preceeding manner by the semen Masculinum is supposed to contact also the membranes that envelop the foetus with the Placenta, Umbilical Chord &c: The Ovum lies in the Uterus 9 months, but for the first two or three months the Placenta does not adhere to the Uterus The Chorionis the external coat of the Foetus it is a thick spongy membrane. The Amnios is within the Chorion it is very thin and smooth, between these two membranes some have described another called Alantois wch. includes the Urine of the foetus carried there from ye. bladder by the Urachus, this is found in some brutes but cannot be discerned in the human species The Placenta is made up of a congress of vessels. How does the Placenta adhere to the Uterus? How is the Foetus nourished? is it by the Mouth; the Umbilical Vein, or by both together? Does red blood go immediately from the uterine Vessels of the As first this want of Navel String, 2d: a diminution of the the Liquor Amnii, 3d. Mucus being found in the mouth & stomach & meconium &c: # 1st. A want of mouth or any passage into the chylopoetic organs, 2d a corruption of the Liquor Amnii 3d. That the liquor Amnii is an exudation from the foetus & consequently not fit for its nourishment &c: the mother through the Placenta to the Foetus & vice versa? from whence comes the Liqour of the Amnios? these are question, that have been differently solved by physiologists. Some have imagined that the placenta adheres to the Uterus by its vessels inosculating with those of the Uterus, others imagine there is no continuation of vessels by inosculation from the placenta to the Uterus, but that the placenta adheres thereto by a kind of cement; for (say they) if it adhered otherwise there must be a laceration (& consequently an inflammation & suppuration) wc. does not happen when it is bro.' away. As to the Nourishment of the foetus many have imagined that it rec'd. nourishment by the mouth & bring many arguments to prove it*, on the contrary others deny that the Foetus receives any nourishment by the mouth but wholly by the umbilical Chord - this is the most viewed Opinion, but for a particular acc't. of the Nutrition of the Foetus in Utero side Med: Essays of Edinburgh and Dr. Shippen’s Thesis for the connection of the Placenta to the Uterus A It was the rec'd. Opinion till of late by all who allowed the foetus to be nourished by the umbilical Chord that red blood was immediately conveyed from the mother to the foetus; Their arguments for it are 1st. that if the mother bleeds to death the Foetus will be deprived of blood also. 2d. Injections pass from the mother to the Foetus. 3d. that hemorrhages happen upon a separation of the placenta from the uterus. 4th that the umbilical Chord will bleed a great quantity when cut &c: but the most modern doctrine that now prevails & wc. answers all the phenomena best is that red blood does not pass immediately from the mother to the Foetus, for before the placenta adheres to the Uterus it certainly cannot, & then it must be nourished by absorption of the Placentine vessels as well before as after its adhersion to the Uterus; we have said before that the placenta does not adhere to the Uterus by inosculation of the Vessels, but by a slight cementation, thence we suppose that the the small ends of the placentine Vessels open into the mouths of the uterine ones, and as the mouths of the uterine Vessels are so large near the time of delivery as to admit a goose quill whereas the mouths of the placentine Vessels are so small as not to admit red blood its very probable there are many of the placentine vessels open into one of those of the uterus. These small placentine vasculae are part of them supposed to absorb the chylous & ferrous nutritious part of the blood in the uterine vessels which the placenta forms into red blood before it is conveyed to the Foetus; The manner how the placenta acts in forming this nutritious fluid into blood is unknown, but it is supposed to perform the office of Lungs in that particular. The placentine vessels having absorbed the nutritious particles of the mother’s blood and and the placenta formed it into red blood it is conveyed by the umbilical Vein into the Foetus, for its increase & nourishment, while the superfluous & unnutritious part is reconveyed by the umbilical Arteries into the placenta & is absorbed by the uterine Vessels and mixed with the blood of the mother; thus instead of a reciprocal circulation between the Foetus & Mother which was formerly Supposed, and is still by some, there is only a secretion of the fluids which pass from one to the other. The Arguments brought to Support this new doctrine are, 1st: That upon the mother’s bleeding to death, the Foetus will not be deprived of any of its blood this Dr. Shippen proved by an experiment he made in Edinburgh before Alexander Monro jun'r he bled a Bitch to death then opened her and took out her whelps which appeared to have lost not one drop of blood blood. 2d. That the umbilical Cord when cut will not bleed but very little, no more than the blood contained in the Placenta, this most Midwives know & it is mentioned by Smellie: but 3d. Lastly the greatest argument of all is that Injections cannot be made to pass from the placenta into the Vessels of the uterus nor vice versa tho' it has been repeatedly tried by the greatest Anatomists notwithstanding what has been said by some to the contrary. A Course of Bandages Bandages are very necessary to confine dressings upon any external part of the body, injured either by accident or by a necessary Operation. Lect: 54th: Bandages of the Head. 1st: Handkerchief doubled & made 3 square put round the head & tied behind 2d: Grand Covre Chef a large square handkerchief doubled to ab.t 2/3 the way & laid on the head the single part so as to reach the Nose, the double part the forehead, wc. double part being uppermost must be fastened under the Chin, the other then turned up & tied behind in the nape of Neck 3d: Poormans Bandage of Galen a piece of linen cut into 6 tails & laid on the top of the head, the middle tails fastened fastened under the Chin the hind ones before & the fore ones at last behind. 4th: Capaline a long doubleheaded bandage 4 or 5 fingers breadth wide to put round the head 5th: Uniting Bandage double headed & like the former with a slit near the middle to be applied to a wound of the forehead. 6th: Scapha for bleeding in the frontal vein going several times round the head at last the first end turned over & tied behind 7th: Kiaster double headed for bleeding in the Temporal Artery going several times round the head then twisted round to a hard knot over the Orifice & then part one end over the crown the other under the Chin and fastened. 8&9 Monos- & Bi-Ocular double headed the first covering one Eye the last both Eyes Lect. Lecture 55th: 10 Accipiter a T Bandage for the Nose going round & tail tied over the head. 11 A four tailed sling bandage for the upper Lip. 12 A four tailed sling bandage for the Chin the under half being the broadest. 13 Capistrum double headed bandage passing from under the Chin to top of the head then to neck & round to the Chin &c: 14. Divisive along double headed rowler to keep up the head. Bandages of the Trunk 15 Spica double headed for the shoulder 16 Star Bandage for a fracture of the Clavicle a single headed rowler & if necessary the Capaline may be applied with it for greater safety. 17 17 For the Thorax the Jenriette or Napkin & Scapulier the first going round the body the latter slit going over the head & fastened thereto. 18 Suspensor of Heliodorus for a diseased Breast a X bandage 19 For Paracentesis a broad flannel roller to go round & compress the Abdomen. Lecture 56th: 20 Spica Inguinis double headed for any disorder in the inguen. 21 T Bandage or Suspensor Scroti beside wc. there are several others of less note to these parts particularly the Truss Bandages of the Extremities 22 Deloer for the Wrist 23 Spica Pollicis for the thumb. 24 Gauntlet ~ } for the fingers 25 Denigantlet 26 26 Eight tailed bandage for a broken Patella &c: 27 For a simple Fracture Thypodesmus going round under the splints a single headed roler & Epidesmus going over the splints one roler very long may serve for both. 28 For a compound Fracture where there is a Wound &c: the 18 tailed bandage together with splints Tape &c: and lastly Junchs, Box, or Cradle &c: if it is one of the Legs. A Course of Operations Lecture 57th:~ Of Sutures There has been many sutures invented most of which are out of use. We ought to observe that a wound made longitudinally in the direction of the ~ Fibres requires no sutures be it ever so great, for by means of a bandage the sides of the Wound is easily brought together without suture. But a wound made obliquely or transversely requires a suture as no Bandage can be made to keep the wound together. The intention of Sutures is to bring the likes of a fresh wound in apposition, that the vessels may inosculate & heal by the first intention, the chief sutures are The Glovers stitch, The interrupted suture, The quilled suture, & the Gastroraphy, The Glovers stitch is performed with a strait needle & waxed thread single, turned over and over. The interrupted Suture is made with a crooked needle & single waxed thread the lips of the wound being brought together first make a stitch in the middle the Rule for which is to begin as far from the edge of the wound as the wound is deep making the needle come out at the bottom of the wound & continued thro' on the contrary side then tied not over the wound but on one side, then make two other stitches near each end wc. is mostly sufficient. Quilled Suture is made with a crooked needle as before with a double cord & tied at the end with a quill on each side the Wound. The The Gastroraphy is performed when the parietes of the Abdomen & Intestines are cut. The intestine is to be saved up with the Glovers stitch leaving a piece of the thread at each end to lie out of the wound of the Abdomen, then the Parietes is to be stitched with the interrupted Suture in a particular manner viz: on each end of a waxed cord must be put a crooked Needle, then take one needle & from within the wound push it out then take the other needle & do the same on the other side of the wound, bringing them together & tying the same, do so until you have as many stitches as you think is necessary Of Trepaning When it is necessary to perform this Operation we should consider first the places where the Trepan may be applied; there are 3 places where it is improper to apply it viz: to the Sagital Suture, the frontal Sinuses, & the Os Accipitis. In Operating, an Incision must be made of a good length through the scalp, the same opened & the Cranium scraped, than having fixed upon the place apply first the perforator & after that the Trepan secundum Artem. Of Fistula Lacrymalis This operation is performed when the ductus as Nasum is stopped & has formed in the Lacrymal Sac &c: Sometimes compression alone will cure this disease but when the Operation is necessary its performed by making an incision over the Sac at the bottom of the Orbit & half the length of the same, into the Sac & cleaning out out the matter & if necessary making an Aperture through the Os Unguis with a strong Probe or a Trocar into the Nose. Of the Polypus of the Nose This is an excrescence growing in the Nose in the Schneiderian Membrane, has different degrees of firmness, in a recent state it is very tender but by degrees grows harder until it gets to a great firmness; the best time for extracting it is when its so hard as not to break easily with the Forceps but not so hard as to adhere to the Schneiderian membrane too strongly. Its extracted by taking hold of it with the polypus Forceps & working it to one side and the other backwards & forwards &c: until it is loosened. Extirpating the Tonsils. This is best done by Ligature for fear of an Hamorrhage if the Tonsils are largest at the apex its an easy matter with proper Instruments to pass the Ligature round its basis & make it tight, but, it often happens that the Basis is largest in this case a ligature put round woud slip off therefore with a proper needle it must be run through the middle of the Tonsils & tied on each side cum node Chirurgica &c: Of Amputation Amputation is sometimes necessary but not near so often as has been thought; all agree that it is necessary in a Mortification, but then it must not be performed until the mortification is stopped & even new flesh begins to granulate. In Amputating the Leg we must stand between the legs that the saw may take the Fibula before the Tibia is quite cut off. we We first apply the Tourniquet to the thigh to stop the blood, then with a strait knife wc. is the best we make a circular incision with two cuts round the leg or thigh through the skin cellular membrane & fat about an Inch below where we intend to cut off the Bone, then an Assistant must pull up the skin as high as possible, after wc. the Operator must make a second Incision through the muscles to the bone then if it’s the leg or forearm the double edged scalpel must be run between the bones to cut the interosseous Ligament & Muscles, lastly the bone itself must be cut off with the saw. & then the Arteries taken up &c: The Fingers are Amputated contrary to all other parts at the Joins by cutting the flesh as before then stretching it up & with the scalpel beginning on the side take off the Joint. Of Empiema This is an operation for letting Pus Water or Blood out of the cavity of the Thorax, oftenest Pus, wc. comes from an inflammation & Suppuration, when this is in but small quantities, the Lungs by then great power of Absorption often carries it off by Expectoration as we see in Pleurisies; but when in great quantities the operation must be performed very carefully for fear of hurting the Lungs between the 6 & 7 or 7 & 8 Ribs with a common scalpel. Of Bubonocele This is the dangerousest operation in Surgery, & not to be performed but when absolutely necessary; when so it is done by making a long incision from above the rings of the abdominal Muscles almost to the bottom of the scrotum carefully in to the Intestine thro' the Peritoneum or Herniary Sac then dilate the passage by incision & carefully reduce the Intestine. Of Couching This Operation is performed for the removal of a Cataract or opacity of the crystaline Lens; there are two ways of doing it, the old way of depressing the Lens with a needle to the bottom of the Eye into the vitreous humor wc. is done by running the needle abt. 1/10 of an Inch below the Cornea into the posterior Chamber behind the Iris & depressing the Lens. The other method, wc. is the new way, much in vogue at present, & I think the best is to cut the Cornea & extract the the crystalline Lens. In the Old way the Lens is very apt to use after it has been depressed wc. makes this new way preferable; it is performed by a small knife with but one Edge wc. is to enter near the place where the Needle enters & pushed thro' into the anterior chamber above the Iris (taking care not to cut it) and out on the other side cutting half or better of the Cornea, then with the point of the knife cut the capsulae of the Lens & its easily pressed out. Of Lithotomy This Operation is performed for extracting a stone out of the Vesica Urinariae; there has been several methods invented to perform this operation but the Lateral Operation or that invented by Irene Jaques is the best & universally in use. We are not to operate until we are certain there is a stone in the Bladder & we can feel it by sounding & all the other Surgeons present. In Operating we first tye the patient on a Table of a sufficient height lying on his back by making a noose with a garter round the Wrist then making him take hold of the bottom of his foot with his hand putting the Garter round his Instep & hand in form of 8 a sufficient number of times, with an assistant to hold each knee then introduce the Staff into the bladder, letting a careful assistant hold the same bending the top a little towards the right Groin is as that the bend of the same may turn a little to the left then then the Operator setting down right before the Patient must with a sharp scalpel make an incision immediately upon the staff from the Base of the scrotum to beyond the anus abt. an Inch to the left of Cerines through the skin & fat, (this should be made thus large that we may get at any Artery if necessary) then make the incision shorter down to the staff when we feel the staff bare we must take the Gorget put the point of it into the Groove of the staff then take hold of the staff from your assistant & turn it over while you slip the Gorget along the groove into the bladder, then take out the staff, & introduce the Forceps upon the groove of the Gorget, when they are in the Bladder pull out the Gorget & gently feel for the stone, when you find it take care to get good hold of, it not being in too big a hurry; when you have it fast extract it. If the stone breaks take out what you can with the Forceps & the rest with a scoop. The wound must be drest gently wth. dry Lint. Med. Hist. MS. B 158 Of Tapping Of Injections The ancients used to employ only Ink for Injections (which answered the end but very poorly) until the time of Ruysch who made his injections of wax, some of wc. have since been improved; his method of Injection was as follows viz. He first laid open the hypogastrium & made two incisions about an Inch long into the Aorta & Vena Cava, then put the Subject in cold water several days pressing out the blood frequently. Next he put them in warm water several days more & put two tubes in the Artery one upwards & one downwards & fastened them tightly. His injection was only simple Suet calomel with Cinnabar in cold weather & in the Summer time he added a little white wax & injected it gently when warm into the vessels, then put the Subject into cold water till the injection was cold, then dried the preparation carefully or preserved it in spirits of wine Injections used by the modern are the follg: Corroding Injection of Dr. Nicholls Rx Wax 4 ounces Resin 3 ounces when melted add Turpentine Varnish 3 ounces Dr. Hunter's Corroding Injections Rx Wax 3 ounces Resin 3 ounces when melted add Venice Turpentine 11 ounces Another Rx Wax 4 ounces Resin 3 ounces when melted add Oil of Turpentine 2 ounces Another Rx Wax 4 ounces Resin 8 ounces or 10 ounces Tallow 3 ounces melt them together The Injection is known to be of a proper consistence by dropping some of it when melted in water & when thoroughly cold forming it into the shape of the Vessels if upon Landing it breaks it is too hard if it bends easily it is too soft & must be mended. Those Injections which have Turpentine Varnish, Venice Turpentine or Oil of Turpentine in them must be tried as above every time they are heated because in heating they loose of their volatile oil Of the Colours To the foregoing Injections such a quantity of colouring matter must be added as will give them a bright colour which must be determind by the Eye Colours generally used are Vermillion Kings Yellow, Blue Verditer & Flake White. Other colours may be used. They are generally to be mixed with the Injections when they are melted; but there are some objections to this rule in some of the colours particularly the blue Verditer & in some measure the Flake White for Navy both ferment when mixed with the foregoing Injections; to prevent which it is necessary to melt some of the Ingredients alone & add the colour to it before the other Ingredients are added. The following Experiments will particularize these Exceptions 1 Blue Verditer with Tallow alone causes no Fermentation 2 Blue Verditer with wax alone don’t Ferment 3d. Blue Verditer with Resin alone does ferment, therefore mix the blue Verditer with the Tallow or Wax alone or together & afterwards add the Resin which causes a small froathing If Turpentine Varnish, Venice Turpentine or Oil of Turpentine be used mix your colour first with the melted wax & then add either of these Ingredients with the Resin These observations are equally true of the Flake White When we make a white Injection instead of yellow Wax we use white. It would seem that we have not yet any Green Colour, but as blue & yellow make a Green the blue Verditer added to the yellow wax or Resin gives us a fine green Dr: Nicholls fine Injection Rx Hard Brown Varnish & hard White Varnish a 5 ounces Turpentine Varnish 2 ounces add the Colour & shake the Vial first putting some shot therein to make them mix. Either of the hard Varnishes will do as well as both adding the same proportion of Turpentine Varnish viz 1 to 5 Another Rx Hard Brown Varnish & hard White do. a 8 ounces Venice Turpentine 2 1/2 ounces mix these as the former If we neglect being nice in our proportions or from often heating these Injections become too hard or Brittle. We know when they are of a proper consistence by the following Experiment; Drop one drop of it upon cold water which will immediately diffuse itself over the whole surface when the spirit will be immediately attracted by the water & the gums with the Turpentine will be left swimming on it, if this will bear raising up without breaking it is of a proper consistence, but if it breaks its too hard & much be softened till it is properly tenacious Of Watery Injections Glue dissolved in water alone makes a good minute Injection; before it is dissolved by heating its necessary to steep it in water for 12 hours then boil it upon the fire till the whole is dissolved, afterwards strain it & drop some of it upon a cold stone or any cold substance to cool that you may know its consistence; when it is somewhat thicker than a common gelly it is of a proper consistence Isinglass & water prepared in the same manner as the preceding ~ makes an Injection similar to it Gum Arabic, Tragacanth, or any of mucilaginous Gum dissolved in Water to the consistence of Cream & strained as the preceeding make a very minute Injection As the Colours mix difficultly with with these watery Injections, they ought first to be mixed well with a little of the Injection & then the remainder added to it. Of Oily Injections We often make Injections of almost all Oils as Oil of Turpentine Hogs lard Tallow &c: The oil of Turpentine is rather too thin of itself but when added to two parts Tallow is a good Injection Butter or Hogs Lard make of themselves a pretty good Injection All fine Injections require more Colours than coarse ones, for as it is to run into much smaller vessels it of course becomes more & more transparent and therefore requires such a quantity of colour as to render it opaque even when it is most minutely separated on diffused within in very small vessels or on any surface Of Common Injections The corroding Injections are too hard for several purposes & the fine ones too soft therefore we need something between them, some of which must be softer than others The hardest is Rx Resin 3 ounces Tallow 2 ounces Wax 1/2 ounce Colour sufficient for an Injectn. is Rx Resin 2 ounces Tallow 2 ounces Colour sufficient for an Injection These are generally used when the part is intended to be dissected Varnishes Turpentine Varnish Yellow Resin 14 lbs Oil of Turpentine 16 lbs, boil the water out of the Resin & then add the Oil of Turpentine from the fire. White Hard Varnish Mastich & Gum Juniper a 1 grain Alcohol 8 grains ~ Brown Hard Varnish Shell Lac & Seed Lac a 1 1/2 grains Gum Juniper 1 1/2 grains Alcohol Galls. 2 clean the Gums from dirt & bruise them pretty small then put them in the spirits & dissolve them in a Sand heat The Spirit of Sea Salt is the corrosion commonly used by Anatomists The part to be Injected must be macerated in water blood warm 2 or 3 days so as to relax the vessels & soak out all the blood in them, then having a proper sized Syringe with pipes of different sizes, fit one of the pipes into the vessel & fasten it well with a ligature bringing the ligature round the cross piece to secure it the latter. The part to be injected lying in the warm water & the Syringe and Injection being warm, the Syringe is to filled with the Injection, the end of it put into the pipe & kept fast & the Embolus of the Syringe pressed gently down with the breast till the part is sufficiently injected or the syringe when it is to be filled and emptied as before if necessary ~ Med. Hist. MS B 158 Med. Hist. MS. B 158 Ex Libris Jonathani Elmer Ipromet manu Jeripris Jonathn. Elmer’s A Course of Anatomical Lectures Delivered By Dr. William Shippen junr. Professor of Anatomy & Surgery in the College of Philadelphia Anno 1766 Quanta autem existerent consilii solertissimi indicia, su tota hominis fabrica perspecta foret? si corporis totius species et dignitas? Sensuum organa subtillissime fabricata, et aptissime locata. Synop: Meta: Anatomia fundamentum est Medicinae Anomal Anatomical Lectures Lecture 1st: Anatomy avatouia in Greek signifies cutting & by it antiently was meant only the dissecting of bodies, but at present it is implied in a more general sense. Anatomy in respect of its object is divided into human and comparative. Human Anatomy is that which is employed on the human body; and comparative Anatomy is that which is employed upon the bodies of other animals, these serving for the more accurate descriptions of several parts, and supplying the defects of human bodies. Anatomy from its various ends may be said to be of four kinds viz: Theological, Medical, Juridical, and Judicial. The The first consists in an acquaintance with the works of the creator in the human frame; according to Fontanel the study of Anatomy & Autonomy afford the strongest arguments against Atheism. Medical Anatomy is ultimately health, for the presentation of which, restoring it when impaired, by diseases, or even preventing their access, nothing surely is more necessary than a true knowledge of the structure of that frame so liable to be injured. Juridical Anatomy is the determining the causes of suspicious deaths, impotency, barrenness, the true times of pregnancy and delivery, the mortality of Wounds and a multitude of other causes of great importance to be adjusted in account of Judicature. Judicial Anatomy is the determining the cause and manner of the death of diseased persons from a subsequent dissection of the body body; this is of the utmost use in the practice of Physic. Upon the whole then the use of Anatomy in very great, nor is it confined to the bounds of Medicine alone; the Philosopher and Theologist, the Magistrate, Painter and Sculptor are in their respective employments more or less qualified in proportion to the progress they have made in this science; but the physician and Surgeon are the people to whom it is most immediately necessary and who without a perfect knowledge of it cannot do justice to the world in their professions. What the needle is to the mariner, Anatomy is to both these, and we may venture to say that without its assistance, they would be rather detrimental than beneficial to mankind. The Anatomy of the solid parts is by Heister called Osteology and that of the soft parts Sarcology, each of these are subdivided. Osteology or the anatomy of the Solid parts is divided into the anatomy of the Bones called Osteology; Chondrology or the anatomy of the Cartilages; and Syndesmology or the anatomy of the Ligaments. Sarcology or the anatomy of the soft parts is divided into Dermatology or the anatomy of the Teguments; Splanchnology or the anatomy of the Viscera; Myology or the anatomy of the Muscles; Neurology or the anatomy of the Nerves; Angiology or the anatomy of the Veins and Arteries and Adenology or the Doctrine of the Glands. In the human body as a complex hydraulic machine a double inquiry must be made 1st. Into the structure of the parts, this is called Anatomy, 2d. Their functions & the laws of their motion which is termed Physiology Lecture 2d. As the solids are formed out of one principal fluid chiefly, called the Blood it is proper to begin therewith. Of the Blood Blood in Scripture is called the life of the Animal; according to some it is the primum vivens ultemum moriens, its a heterogeneous mass, as is evident from the variety of ingredients of which it is made up, and the various forms it assumes in the animal machine. The blood is composed of three substances viz: Serum, Gravamentum & a coagulable Lymph: We shall consider these in three different manners; first when ocularly examined, 2d. Viewed with a Microscope, and B 3dly: The chemical Analysis thereof. Blood fresh drawn from a sound living animal, upon landing, part of it congeals into a hard coagulum suspended in a yellowish Serum, the upper surface being of a florid color while the bottom is black; the reason of the blood appearing bright and florid at the top is from its being in contact with the Air; this is confirmed by an experiment of Dr. Hunter’s who put a quantity of blood fresh drawn into a vial, & stopt it close; upon standing it all turned of an uniform black color, except a little spot upon the top with which a globule of Air had got in contact. Blood stirred round with a probe whilst Whilst warm, a fibrous elastic substance is obtained, which, put in water turns of a whitish color; this is the coagulable Lymph, is strongly elastic, & is the cause of cohesion in the particles of the Blood, as is evident from the extravasation of the blood after death by dissolution of the cohering particles. The coagulable Lymph is sometimes discharged from the Uterus and by Nurses taken for an Abortion; this error they are sometimes led into from a desire that it should be so. If spirits of Wine be added to Serum, or the same made boiling hot, it rises up, emits fumes, and turns into a coagulum similar to the White of an egg: the fibrous part of the blood is what forms Polypuses Polypuses concretions &c: Blood viewed by a microscope appears to consist of a number of globules, the larger ones being those that tinge it of a red color, &c: therefore chiefly make the crassamentum, are of a certain determinate magnitude being of the same bigness in all animals, in a Sheep as in an Ox, in an eel as in a man. These globules are composed of six smaller or ceruminous ones; and these ceruminous ones are composed of smaller or lymphatic ones; and it is probable there are still lower orders of globules of blood. These globules of blood are of a lenticular form and elastic the largest kind being less than the 1/3000 part of an inch Inch. the crassamentum is supposed to contain 1/3 of the mass and the Serum to make up the other 2/3. Blood chemically analyzed; upon distillation with a slow fire a quantity of Phlegm arises, with the fire increased next arises an Oil and a volatile Salt, the caput mortuum being a fixed alkali and a cretaceous Earth. The chemical proportions of the blood are by Dr. Martin & Boyle recvd. as follows viz: of Phlegm 5/6 of Oil 1/15, of Salt 1/25, of Air 1/20, & of Earth 1/75, part of the whole mass. The specific gravity of the blood to that of rain water is by Dr. Jurin and and Martin reckoned as follows, by Jurin as 1000 to 1054 by Martin as 1000 to 1056 or 1057 or as 10 to 19. The density of blood in living animals is to its density when reduced to the coldness of temperate Air as 134 to 135 or 992 1/2 to 1000. The color of blood is for the most part red, but redness is not a constituent quality in blood, for some Animals have white blood. In the human body the blood is redder & more florid in the Arteries than in the Veins, oweing to the action of the Lungs upon it, for by shaking fresh blood in a vial taken from a vein, it appears of the color of arterial blood. That the blood is is reder in the Arteries than in the Veins. Dr. Hunter proved by the following experiement: he opened the Thorax of a live Dog and kept his Lungs working with a pair of Bellows; and drew a spoonful of blood from each side of the Heart is, from the Vena Cava & Aorta the latter of which appeared the reddest. From the accurate experiements it is found that a cubic inch of rain Water weighs 253 1/3 grains, a cubic inch of warm blood 264 3/4 grains. An Ounce of Blood contains 1,813 Inches, an avoirdupois ounce weights 437 1/2 grains equal to 1,727 inches of water and 1,6526 of warm blood. Lect. *Among these we may reckon Boerhaave instit. vol. 2 the colour of the Arteries are of aligamentous substance and not muscular as is evident from their white appearance and their of elasticity both of which is contrary to the general characteristic of a muscle however we are informed that Dr. Cullen has lately discovered that there are muscular fiber in the coats of the arteries the action of which he thinks assists in propelling the blood onward. J. Cullen likewise says that there is a muscular coat to the arteries as well as Boerhaave & many others. &c physiology [illegible]. Lecture 3d. Of the Arteries & Veins An Artery is a strong, membranous, ramifying, elastic Tube, endowed with pulsation; arising from the left side of the Heart, and terminating in every part of the body. The Arteries are composed of three coats, tho’ some have reckoned four and some five.* The first external coat is very thin the fibres of x which going longitudinal & circular; the second coat is thickest and the fibres of it go in a circular direction; the 3d. coat is very compact and its inside very smooth and even, this smoothness and compactness of the inner coat serves two purposes. 1st. to allow the blood to to pass without hindrance & 2d. to prevent its exudation. The pulsatory motion of the Arteries is a dilatation and contraction of them; the former called Diastole, and the latter Systole, which precedes proceeds from the Heart, besides which they have a sort of aperistaltic motion, as is evident from an experiement of Dr. Hunter’s, who opened alive Dog and cutting off the mesenteric Artery, injected it wth. a warm milk, which he could plainly perceive the Artery to carry along wth. a vernicular motion; to confirm is the more he injected the mesenteric Vein but the milk went no farther than the & the force of the injecting propelled it. There are but two Arteries in the body viz: the pulmonic, which carries the blood through the small circulation, and the Aorta, which carries it to all the parts of the body. The coats of the Arteries are very elastic, and are furnished with blood vessels for their nourishment; the Arteries mostly and all except the Epigastric ramify at acute angles. The commonest diseases the Arteries are subject to, are, Aneurisms and Ossification. Aneurisms proceed from a preternatural dilatation of the coats of the Artery’s and are of two kinds 1st. When the blood is x it is sometimes found in young subjects and is oweing perhaps to a disposition of the constitution to form bony matter. is contained within the coats of the Artery. 2d. when the Artery is burst & the blood extravasated into a membranous bag. Ossification happens mostly to Old people from a weak & slow circulation of the Blood. x Veins are elastic, ramifying Tubes, like the Arteries; except smaller. their coats thinner, and without motion. Phisiologically speaking the Veins begin at the extremities of the Arteries, or more properly speaking they are a continuation of the Arteries reflected back toward their Origin the Heart; but anatomically speaking the Veins arise from the Heart. There There are 7 Veins in the body from which all the rest arise viz: The 2 Venae Cava ascendans and decendans; 4 pulmonary Veins (two from each lobe of the Lungs) and Vena Portarum. The veins are mostly ramified in the same manner as the Arteries, exct. the Vena Portae, and the cutaneous Veins of the extremities, & other parts. The veins of the extremities have valves, but not those of the Viscera; the reason of which is because there is no Muscles in the viscera; hence the use of those valves in the Veins of the extremities is to prevent the blood from going backward as well as x Bellini especially is of this opinion as well as for, to push it forward when the muscle is contracted and the Vein compressed. Of Venesection & Hemorrhages. In bleeding, the blood is supposed to x flow out faster at the orifice than it circulates in common, and to increase the circulation to the part, hence the doctrine of revulsion & derivation is easily understood; thus we find in a Cephalalgia bleeding in the foot causes a derivation to the feet and a revulsion from the Head &c: In Hemorrhages the antients used Ligatures round the joints, wc. stopping the return of of the blood to the Heart checked its impetus, but but by Venesection his ends are answered: e,g, supposing an Hemorrhage at the Nose, Lungs, Uterus &c: bleeding takes off the impetus of the blood & causes a revulsion, at the same time. Dr. Haller thinks this latter method much the [illegible] the Veins are some of them subject to Varices, which are an obstruction, or destruction of the valves thereof. The muscular coat of both the Arteries and Veins are somewhat subject to inflammation & suppuration, but not near so much as the other muscles of the body; this is very wisely adapted to their function, for suppuration of their coats would be attended with fatal consequences often. Lecture Lecture 4th. Of the Lymphatics. Lymphatic or absorbent vessels are those fine ramifying vessels which contain a clear diaphanous Liquor; they take their rise internally from the cavities, as the stomach, intestines, and externally from the surfaces of the skin. The antients supposed the Lymphatics were a continuation of the Arteries dividing them into three classes, sanguineous, venous, and Lymphatic, but, it has very lately been discovered that the Lymphatics are an entire system of vessels by themselves, having no affinity or communication with either the arteries or veins. this This is proved 1: by injections not passing into them from the arties 2: by the motion of the fluid in them and the valves they have; they are called absorbents from their office, which is to absorb the Lymph and other matters and carry it into the thoracic duct or Receptaculum Chyli; where they are all supposed to terminate. Those vessels called lacteals belong to this system; and called Lacteals only, from their carrying a milky chyle: their origin termination and course of their fluids being the same. That the lymphatics are absorbents is evident from their absorbing moist substances rubbed on the skin, as Mercury, Turpentine, Garlic &c: but in a more obvious manner in the venereal Disease, where absorbing D the virus they carry it to the adjacent Lymphatic Glands and cause them to tumify, hence Buboes &c: sometimes the virus causing the glands to tumify and inflame, constricts the vessels beyond the same and prevents the infection from going any farther; hence the cure of the venereal disease sometimes by the suppuration and discharge of a Bubo. Of the Glands. A Gland is a secretory Vessel — the antients called only those Glands which we feel hard movable kernels under the chin and other were until Malpighius by his microscope found the Liver and other substances to be of the same texture, and therefore termed them all Glandular. A A Gland he thought to be made up of little fine round bodies consisting of Follicles which contained the secreted fluid and between which was a parynchemical substance; but Ruysch by his injections found that the Glands were vascular or made up of fine vessels which has been further confirmed by later anatomists. The vessels of the Glands are Arteries, Veins, secretory and to some excretory Vessels Nerves & lymphatics Of Secretion Some have imagined that the secretions were performed by the diameters of the secretory vessels, supposing them to be of the size of the particles secreted; but this theory is subject to these two objections, viz: that the smaller particles will will go off with the larger ones and to the secretion be confounded and in a Jaundice, when once the Bile had got into the Blood it would continually remain [illegible] & the Jaundice could not be cured; others supposed a particular fermentation happened in the veneral glands, & from thence arose the difference in the veneral secreted fluids, and likewise was the cause of the secretion; this theory is liable to the same objections with the former, and therefore the most received opinion is, that the secretions depend upon the particular disposition of the vessels, to the particular fluid it is to secrete; hence arises these Axioms. 1st. That the secretions are carried on uniformly in a living sound Animal. 2d. One secretion increased another is diminished &c: Lect. Lecture 5th. Of the Muscles & Tendons. A Muscle is a fleshy, fibrous, [crossed out] substance, consisting of Veins, Arteries, & Nerves; besides fleshy fibers &c; having more nerves in proportion than another part of the body serving to give notice to the brain of any external stimulus or irritation. The redness of the muscles is not inherent in the fibres thereof, but only oweing to the blood contained in them, of which there is a great quantity, more than is sufficient for their nourishment and may possibly be subservient to their motion. A Tendon is a white compact fibrous unelastic substance. most muscles terminate in Tendons, and the Tendons are by some reckoned a continuation of the fibres of of the muscles to which they belong, only more compacted together so as not to admit the red globules of blood between their interstices: but Dr. Hunter thinks the fibres of the Tendons are not a continuation of those of the muscles, but distinct fibres someway cemented thereto. The muscular fibres are cemented together by the cellular membranes and an intervening glue, & serve for the moving of the solid parts of the body. The Tendons are for the better insertion of the muscles, and of great use in motion; eg: in the Perforans and Perforations of the hand, the muscle arises from the inferior part of the Humerus, and if that was continued down to its insertion muscular, it would render the hand troublesome some and unwieldy, whereas now, the Tendons, being compact & taking up but little space, remedy that inconvenience. Round many of the Joints as the Wrist Ancle &c: there is a capsular Ligament or Frenum which serves to keep these tendons in their right places, and facilitate their regular motion; likewise over some of the Muscles there is a tendinous expansion called Aponeurosis, of much the same use as the preceding Ligament. The muscles may be reckoned of three kinds first Oblong as those of the Arm, 2d. Convex as those of the Heart, Stomach, Bladder &c. 3d. mixt as those of the Abdomen the Pectoral muscles &c: Muscles have their names from their Origin, Insertion, Use Appearance &c: Lect Lecture 6th. Of the Nerves. The Nerves are now by every body allowed to be a system of the vessels, and they are a fasciculi of white fine fibres, arising from the Medulla Oblongata & Spinalis, egressing in pain. Over the Brain are the Meninges, or, 1st. The Dura Mater which is externally, & a thick vascular substance within this & adhesive to the Brain is, 2d. The Pia Mater, which is a thinner membrane; between these two, some anatomists reckon another membrane, extremely fine & reticular which they call Tunica Arachnoides. The Brain is divided into three portions called, Cerebrum, Cerebellum, and Medulla Oblongata, the latter being being continued thro’ the spine of the back is called Medulla Spinalis. The Brain is supposed to be vascular, & its substance of two cortex; external of an Ash color is called Corticalis; internal of a white color called Medullaris. The Nerves are of the same substance with the Brain, and are properly aportion thereof continued to all the parts of the body. The Nerves as they arise in pairs soon after decussate, or change sides as in the Optic Nerves, the left going to the right Eye, & the right to the left; hence a wound, on one side of the head affects the contrary of the body. The Nerves are distributed thro' the body in much the same manner as the Arteries; the one proceeding from the Brain the other from the Heart, but with this difference & difference, that the trunks of the Arteries grow less the more they are ramified together with the ramifications ad infinitum; but the capacity of a constituent Nerve never decreases they being imperceptible, but the number of the likes of the Fascicule decreases in proportion as the bundle ramifies, thus the cords of the Nerves wc. as they egress from the Brain contain an innumerable number of constituent Nerves, decrease in No. but not in capacity ad infinitum in proportion as they are ramified. The Nerves anastomose, but not in the same manner as the blood vessels do, by uniting their tubes but only by their coming in contact with each other; these anastomoses are called Plexuses. sometimes little knots appear in Nerves called Ganglions, some imagine these knots proceed from pressure & inflammation, but this cannot be as they are found found in the Viscera, & in a Foetus where no pressure could happen. Lancesi, reckons the use of these Ganglions is for an an additament to the Brain; because he says more nerves go from them than go to them, but from the substance of these knots not being the same wth. the brain, that cannot be. others think they serve to stop the nervous fluid from flying out at the end of the Tube without the impulse of the will by means of muscular fibres, they being only in those nerves destined for voluntary motion; this also appears to be false. The termination of the nerves is but little known, but supposed to be in every part of the body. The use of the Nerves is for sensation, motion, nutrition, &c: the Brain being called the sensorium Comune to wc. the Nerves carry all the sense communicated to them Voluntary Voluntary motion is acquired by experience, as is evident from a child whose will is frequently contrary to the Act performed. Of the cellular Membrane. The cellular membrane is of two kinds, the one adipose containing fat, the other reticular without fat; it is a net like substance, vascular, very thin and tender, consisting of many cells & its fibres very fine: the cellular membrane is continued throughout all the body, except some of the viscera & is called by some the membrana Musculorum Comunis. The cells of the reticular part of the cellular membrane communicate with each other, as is evident from an Anasarca which is a transudation of Phlegm into the cells, & so from the one to the other, as is evident from the Legs swelling by walking & subsiding when lying down x See the Londn: med: observations vol: 2 down; hence Eccymosis from a false Aneurism, Diaeresis, Contusion &c: by which the blood insinuates itself into the cellular membrane; hence also the great quantity of water evacuated from a scarification in an Anasarca. An Emphysema is a remarkable proof of the communication of these cells; this is caused by the air distending these cells & often happens from a fractured rib puncturing the Lungs by w.c the Air gets into this membrane; a remarkable instance of this happened in London, by w.c the patient swelled to that degree that his eyes could not be seen; Dr. Hunter x made a puncture at the Eye by w.c the air gushed out, & by puncturing & rubbing he was cured. Putrefaction will cause an Emphysema, from the fermentation generating air; hence hence a drowned person will after a while rise to the surface of the water. The fat contained in the adipose cells differs in different bodies; in a Foetus the fat is soft, and gelatinous; in children of a year or two old, the fat is chiefly next to skin; hence the fatness observed in children; & in adults the fat is solid and mostly internal. The cellular membrane serves for easy smooth motion, for a defence to the body, to keep the parts warm & preserve the figure of the body, & blunt acrimony. some animals we reckoned to be nourished in the Winter by their fat. Lecture 7th Of the Bones. Here we shall, 1st. describe the external conformation of the Bones, 2d. examine their internal structure, 3d. their connection, & 4th. Explain their use. A Bone is a hard fibrous compact substance. various Bones have various shapes & conformations, some are cylindrical & long, others flat, & broad, irregular &c: bones are said to be made up of Fibres forming Lamellae, fastened together by means of oblique or transverse fibres. Bones have processes and Cavities. Processes have different names from their different forms, & appearance: thus, a Condyle is an oblong process arising from the extremity of a bone; a Corone is an oblong process process terminating in a point; Spine is the sharp ridge of a Bone; Supercilia is a brim round a cavity; a protuberance is a rough process of a bone. Processes are of two kinds viz Apophysis, & Epiphysis; Apophysis is a process growing out from the body of a bone. Epiphysis is a process growing to the body of the bone, being originally separate therefrom by a different Ossification. The cavities in bones are of two kinds, one for Articulation, & the other for the lodgment of soft parts; cavities for Articulation are of three kinds, 1st. Round & deep called Catyloid, 2d. round but superficial called Glenoid, and 3d, deep & narrow called Alveoli, the Articulation of Bones is by Galen called [illegible] Joint & by him is reckoned of 2 kinds, 1st. With motion called called Diarthrosis. 2d, without motion called Synarthrosis; each of these are of 3 kinds. Diarthrosis, are. 1st: Enarthrosis, 2d: Arthrodia, 3d: Ginglymus. Synarthrosis are, 1st: Suture or Raphe, 2d: Harmonia, 3d: Gomphosis. The connection of bones is termed their Symphysis, & is of two kinds: the one wth. and the other without an intervening substance: the first is that of the Cranium by mutual Indentation. the second are of 3 kinds viz: Synchondrosis, Syneurosis & Sysarcosis. Periosteum is an elastic fine membrane, that covers the bones except at the joints teeth &c: its case is for the insertion of vessels, to strengthen the Epiphysis &c: the cylindric bones are all hollow, & so are most others & contain Marrow, the ends of the bones are cellular. F Lect. x see Edinburgh med: Essays. Lecture 8th Osteogonea. In a Foetus, the first months, there are no bones, nothing but a gelatinous fluid; then it gradually grows cartilaginous, & in time becomes boney; some imagine Bones are formed of Cartilages only by an expulsion of the redundant fluids; but Dr. Nisbet x says, & it is now general recd., that in Ossification, there is in the blood, or a fluid secreted therefrom, an ossifying juice; consisting of particles wc. are not apparent; that wherever nature designs an ossification between membranes, or a cartilage she occasions a more than ordinary afflux of fluid which distends so much the vessels wc. were before invisible as to make them capable of receiving the red globules of blood wc. is always to to be seen near to where ossification is begun. In this blood gritty particles are to be felt by the point of a knife, which have been formed by the attraction & cohesion of the particles of the ossifying juice obstructed along with the other grosser fluids in the beginning of the vessels, prepared to receive the influent juices. The membranes or cartilages some as alied between wc. or within wc. the bony particles are deposited or shoot; but without any any intermixture of the particles of the bone & cartilage, or continuation of the fibres of one substance to those of the other as is evident in bones made perfectly clean, the cartilage dropping from it as easy or easier than an acorn from its cup, & there is a smoothness of the parts of both cartilage and and Bone which show that there is no conjunction or union of the fibres of the two substances. While bones are increasing within Cartilages, the cartilages are extended & spread out, by wc., with the pressure they suffer & the great influx of various fluids, & the nutritious matter being kindred to flow freely into them, they decrease continually & at last may truly be void to be entirely destroyed. Bones digested in Acids for sometime grow flexible & gelatinous like a tendon, by which it appears the great quantity of Earth they contain makes them hard rigid. Bones are furnished with Arteries and Veins, as is evident from the drops of blood blood seen in sawing bones lengthwise, & upon their appearing tinged of a red color after the animal has eaten Madder. Dr. Havers divides the blood vessels into sanguiferous, & medullan the latter enter the bones mostly near their center in an oblique manner. Bones have Nerves as is evident from their exquisite sensibility where amputated, or exfoliated, & granules of flesh have sprouted out. Diseases of bones are 1st: a softness & rickety disposition. appearing generally from [illegible] to the 3d. year after birth, though the habit may continue thro' life. It seems to be owing to an Idiosyncrasy or a want of bony matter in the constitution. Sometimes it is said to arise from the pox & scurvy, but probably less frequent than from the other cause. We have the history of a species of Scurvy in France that affected the Bones & separated the Epiphysis. In Anson’s voyage we are told the Callus of bones wch. had been fractured & united again for may years were disposed by this Scurvy ~ Softness from a venereal Taint can be nothing more than a Caries of the bone. the disease first affecting the Periosteum & then communicating itself to ye. subject bone. As to softness from Idiosyncracy as its called; or from a particular state of the solids & fluids. Mr. Goodye furnishes us with a history of a woman whose bones without any apparent cause grew soft; her body shortened, & at last she died, & he found that he could easily cut through the limp bone & all. The academy of Paris give a more remarkable history of a woman whose bones were so soft that at length they had not solidity enough to gird the muscles action—no kind of a scorbutic or pocky taint could be observed. see Vanss 4h:423. Mr. Gooch had a case of this kind under his care, when the patient died he found the bones so soft that he split the thigh bone, the Tibia & bones of the foot the whole length very easily with his knife. Dr. Tilton of Dover relates the like Bones may likewise loose of their bulk like other parts from a loss of juices as in alveolar & vessels of old people. 2dly: Fractures. All bones have a tendency to unite again after being disjoined w:ch is effected by means of a Callus this was formerly supposed to be unorganized, but is now known to be vascular by injections & being tinged with madder. When a Callus is broke it will unite again only to the opinion of some authors. A pupil of Dr. Haller’s in a Thesis he wrote on the subject say that the Callus is first a bloody matter, then slimy, next gelatinous & then vessels from the bone & meditullium shoot out thro' it & ossifications begin directing themselves quaquavenum & thus the Callus Lecture 9th Of the Cartilages & Ligaments. Cartilages are compact, opaque, & a little elastic: of wc. there are 3 kinds, 1st: such as supply the place of bones as the Nose, Trachea Artena &c: these preserve the structure of the part & admit of motion. 2d. such as supply the place of bones before they are formed as in a Foetus. 3d. such as serve for the Articulation of bones. Cartilages differ from bones in not having Fibres nor blood vessels to be siphoned, tho’. they are imagined to be vascular; they serve at the Articulation by their smoothness to prevent abrasion; they won’t granulate nor exfoliate but may be corroded. Ligaments is compleat. sometimes the bones won’t unite but with great difficulty. 3dly: Caries. A caries in alone is similar to an ulcer in the flesh it has circulation but it is unsound & often shoots out irregularly as the fungus of an ulcer See more so in med:[illegible] 2:h:k0 [illegible] [4?377]. 4thly: Spina ventosa – this is a caries beginning on the inside of the bone & affecting it clear thro', hence Surgeons bow into the bone to let out the matter, but in general the limb is to be taken off. See Van Swieten 4 p 377 A node by some is said to be an Exostosis of the bone, but for the most part if not always it begins in the Periosteum. should be open'd before it affects the bone 5ly: Anchylosis is a stiff joint having little or no motion. from the bones running into each other & the cartilages being eroded. Van swieten vol 4 p 457 gives several curious cases of Anchylosis of all the joints in the Body. See also Le Bran’s Surgery. x where it covers the Cartilage. it is calld. Perichondrium the external lamina of the capsular ligament goes from the substance of one bone to the other over the articulation & is inserted beyond the Epiphysis &: Friction 6th. Exostosis is a tumefaction of a Bone or an excrescence growing out of the bone. It may proceed from a redundancy of ossifying particles in the system or in the part only from a morbid cause see Van swieten 4 p 424. See the case of 9: Scott of the Pennsylvania Hospital in my Adversar: med: See Cheselden p 5. Ligaments are firm, compact, unelastic, membranes; serving to connect the joints, prevent luxation &c: The Ligament, Bones, Cartilages, Tendons & Dura Mater are now reckoned none of them to have much sensibility in a natural state. v: Whytt & Haller The capsular ligaments are very strong & compact, & made up of hard Lamella, the inner lamella being a reflected membrane going over the head of the joint. cover the Cartilage x & so coming to join the external lamella, which is firmly inserted near the joint. These capsular ligaments forming a sac in wc. is contained, a mucilaginous liquor serving to lubricate the joint: for for in all Joints; for motion there are synovial glands which discharge the above synovia, this is subject to be disordered: 1st. to become thin & Icorous, 2d thick and inspissated &c: It is generally received of late, that the capsular ligament is lacerated in a Luxation of a joint unless from internal cause, or a relaxation; & violent extension is unnecessary in reduction of the same; no more being necessary than to bring the ends even, and then coax them into their proper places, & there keep them by proper dressings & bandage. For as particular description of the Bones vide Monro’s Osteology, and of the muscles Douglas’s Myographia Lect. 40th: In the Osteology we divided the body into three parts, viz: Head, Trunk, and Extremities; the Trunk of the Skeleton we subdivided into, the spine, Thorax, and Pelvis, but in a fresh subject we divide the Trunk differently, viz: into The Thorax, and Abdomen, or upper, & lower belly. The Viscera of the Thorax are only the Heart, and Lungs, & therefore not necessary to be subdivided. The Abdomen is separated from the Thorax by the Diaphragm. The Abdomen by reason of its largeness and the many Viscera contained therein, has been divided into several parts, by imaginary lines, for the readier knowing the particular situation of each Viscus. The divisions are as follows, 1st G 1st. That which lies under the Cartilage Xyphoides, is called Scrobiculus Cordis, 2d. From the Scrobiculus Cordis down to within 2 or 3 inches of the Umbilicus is called Regio Epigastrium, circumscribed, and on each side there of it is called Regio Hypochondrium. 3d. From the Regio Epigastrium to 2 or 3 fingers below the Umbilicus is called Regio Umbilicus, circumscribed, and each side Regio Lumborum, 4th. From the Umbilical Region to the Os Pubis is called Regio Hypogastrium, and on each side the Regio Hiaea 5th. The lowest part is called the Regio Pubis. As we are sometimes called to open the body of a deceased person before their friends, particularly if they died of a violent death; we should endeavor to to do it with regularity & decency. The antients opened the Abdomen by beginning at the Sternum & directing the knife along the False Ribs to the Loins, then along the spine of the Ilium to the Os Pubis; and laying the loose part over on the contrary side. Others begin at the Xephoid Cartilage & make a straight incision down to the Umbilicus, then dividing the incision directing one to the spine of the right, & the other to the spine of the left Ilium, and turning each part back. But the best method is to begin the incision at the Xephoid Cartilage and going straight down to the Olsa Pubis and then another transverse from the Navel to the Loins each way. The Thorax is opened by pushing off the Teguments & Cutting the Cartilages by the Sternum. Lect. All the internal superficies of the cavity of the Thorax, the ribs, cartilages of the ribs & convex side of the Diaphragm except where the pericardium lies in contact wth. it are lined with one continued, thin, nervous, very strong membrane, internally very smooth called Pleura. On the external superficies of this every where is the cellular membrane wc. in very fat animals is often so enlarged with fat as to lessen the capacity of the Thorax & these cause a shortness of breath. The Pleura when it gets round to the vertebra elevates itself perpendicularly lowd. frenum wc. with the one on the other side from a doable pleura called Mediastinum dorsale. The same duplication is made of the Sternum when it is called mediastinum pectorale. The pleura likewise covers all the muscular circumference of the diaphragm above the cellular membrane wc. arising up together with the orb of the septum from the back sternum, from the external membrane of the pericardium wc. is the third cavity of the Thorax in the middle between the 2 cavities of the pleura containing the Lungs & formed a conjunction of them This membrane of the pericardium is lined internally with a thin membrane wc. is a branch of the external membrane of the Heart. The great vessels from the Heart as they pass thro' the pericardium & go on beyond it or move also at above the cellular one from the external membrane of the pericardium. this membrane forming about to the pulmonary arteries & using wc. when they arise at the Lungs is expanded out & forms the extenal coat of the Lungs. Kaan de Perspi Hippocrat. Lect. 41st: Of the Pleura. The Pleura is a fine membrane, which lines all the cavity of the Thorax and is reflected back over the Lungs. There are two Pleura one on each side, like two bladders beginning as we may suppose at the sternum and going round within the Ribs to the Vertebra of the Back, then reflected back upon the outside of the Lung (making the coat of the Lungs) to the sternum; there running in or uniting with the first Fibres of the same and so on the other side; where the two Pleura meet at the sternum; they are not quite in contact with each other, but there is a small space left between which is filled up with cellular Membrane. Of Constat pulmo duplici vasorum genere, aerifero scilict & sanguifero. Aerifera omnia vasa ortum ducunt ex una trachea, quo mox a faucibus intitium capiens, ante oesophagum, descendit, thoracem post thymum intiat; post cavem descendentem & pericardii apicem, as quartam thoracis vertebram, qua est a superiore una tertia pars ipsius pulmonum longitusinis divaricatur. Hujus dein crura tendunt ad utrumque pulmonem, & statim dividuntur, in homine dextrum in tres, sinistrum in binos ramos, qui tune bronchia dicuntur, as totidem pulmonum lobos, quos ubi ingressa funt, disperguntur statim in ramos minores, & minores; qui omnes ad obtusum angulum, respectutrancorum, oviuntur. Remi autum majors ingressi pulmones, pro maxime parte, descendunt, pauci recti procedunt, ubi ingrediuntur; aliivero adscendunt aeriferorum truncorum, & horum ingressum est. quod prater Eustachium meminen observasse video. Ultimi Of the Lungs. The Lungs are Vascular Substances composed chiefly of Air Vessels, and Blood Vessels; the Air Vessels are Ramifications of the Trachea Arteria, and are called Bronchia; the blood Vessels are ramifications of the Vena and Arteria Pulmonalis; beside-which they have an Artery wc. serves to nourish them, called the Bronchial Artery coming from the Ascending Aorta together with Nerves and Lymphatics, and some say also Parenchyma which is perhaps no more than cellular Membrane. Some Anatomists suppose there are little follicles or cells at the extremity of the small Bronchial Vessels, which if there is are not discernable. Ultimi autem ramuli ommitunt cartilagineam indolem, & expanduntur in vesiculas oblongas, membranaceas, cavas, qua Malpighiana dicuntur, ox quibus fiunt area, & lobuli, qui tandem pulmonum lobos efficiunt. Comitantur aerifera hac vasa, in omni decurser, ad vesiculas usque, vasa Sanguifera, qua omnia oriuntur ex arteria pulmonali, qua cordis dextro ventriculs egressa, qua parte superiore ventriculs sinistro jungitur, adscendit, mox se incurrat, arcum facit, & sub aorta decumit. Descendit The inside of the Trachea arteria is lined with a membrane in which are small glands that secrete mucus for lubricating the its internal surfaces; in cold, this means is sucked into great quantity—sometimes inspissated is spit up very thick especially in the morning. Dissection has taught us that this membrane is the seat of that disease in children called the Hives & is found separated from the cartilages – nothing proves so useful in this disease as large doses of 8. I have known 10 g of calom: given to a child 2 years old produced 2 copious stools & disease immediately vanished The Lungs are divided into two Lobes, by means of the Mediastinum and Heart. The right Lobe is divided into three Lobuli by fissures; and the left Lobe is divided into two Lobuli. In a natural state, the Lungs are every were in contact with the Ribs, so that there is no vacuity left. The Trachea Arteria is composed of cartilaginous Rings, which behind are not quite shut but a small membrane between; each of the cartilages are connected likewise by membranes. The Lungs are liable to inflammation, and Ulceration. In inflammation of the Lungs we should use plentiful bleeding, oiluants, fomentations externally and the steams of warm liquors particularly Vinegar, into the Lungs thro' the mouth. x The ventricles are divided by a middle partition called Septum Cordis. Lect. 42d: Of the Hearts. The Heart is a strong muscular substance, situated obliquely to the left side, more than the right; part of the inferior and or Apex in contact with the Diaphragm, and pointing between the sixth and seventh Ribs on the left side; the Apex being likewise nigher the sternum than the Basis. The Heart is the Origin of the Veins and Arteries. There are four cavities in the Heart, two Auricles, and two Ventricles; x one right and one left, at the right Auricle the Vena Cava enters, and at the left: the Vena Pulmonalis; at the right Ventricle the Arteria Pulmonalis egresses, and the Aorta from the left. M x these cordae Tendineae arise from the Carnae Columnae. At the entrance of the Vena Cava into the right Auricle of the Heart are three Valves called Valvula nobilis, and about the middle of the Auricle there is a little knob called Carna Sesamoidea: At the entrance out of the right Auricle into the right Ventricle and two valves called Valvulae bicuspides, connected by sou:e small tendinous cords called Cordae Tendineae x; the internal part of this Ventricle is rough & muscular having many muscular Pillars, called Carnae Columnae which serves for to strengthen the motion of the Heart and to work the blood so as to prevent its concretion & forming Polypuses,- which however sometimes happens. After the blood has passed out of the right Ventricle into the pulmonary Artery it is prevented from returning by three valves Valves named Valvulae Semilunares. There are likewise Valves at the entrance between the left Auricle and Ventricle named Valvulae Mitrales fastened by the final Cordae Tendineaes on the left side of the Heart. The left Ventricle is larger and a stronger & much thicker muscular bag than the right Ventricle, its internal part tougher and the Carnae Columnae bigger. As the entrance out of the left Ventricle into the Aorta are likewise three Semilunar Valves. The Heart is contained in a strong Membranous bag called Pericardium the internal part of which bag is very smooth and lubricated with a juice that continually transudes through the same H. Same Dr. Plott in his History of Staffordshire attests of his own knowledge the case of one Mary Eagle who drew two quarts of milk from her breasts every day besides what her child sucked and that she could make two pounds of butter every week ever since she was brought to bed which was above five months when the Dr. saw her. Borellus in his Hist: & Absence: physioc-med: related an instance of the like native in one Mary Caron a Taylor’s wife of Bologna who afforded milk enough for two children & made Butter besides Biog Dictionary Led: Esq: Lect. 43d: Of the Diaphragm The Diaphragm is a large Muscle between the Thorax and Abdomen, the muscular fibres of which arise from the internal part of all the ribs below the sternum, and from the lower end of the sternum, these fibres terminate in a tendinous expansion which is nearly in the middle of the Diaphragm, and which is of an oblong figure coming very nigh the sternum upon which part the Apex of the Heart lies, and from thence turning down towards the Angle of the Ribs and is called the oval tendon of the Diaphragm the lower part of the Diaphragm is likewise muscular and on each side of the Vertebra are muscular Fibres sent Sent down some distance called the Crura of the Diaphragm, these terminate near the Origin of the Psoas muscles which arise at the internal part of the Vertebra of the Loins and pass out of the Abdomen at the Inguen to be inserted into the Os Femoris. it is by making way through these muscles that Abscesses of the Loins sometimes fall down to the Thigh and are opened and discharge their contents there. There a three Apertures thro' the Diaphragm, one of the right side of the Vertebra through which the Vena Cava goes, a second contiguous to the Vertebra inclining a little to the left thro' wc. goes the Aorta, a third over the Aorta & exactly over the Vertebrae through wc. the Oesophagus goes. Of Lecture 44th: Of Respiration Respiration is an alternate dilatation and contraction of the Thorax the former performed by Inspiration and the latter by Expiration. The parts subservient to Respiration are divided into Active and Passive The active parts are the Ribs, Sternum, Heart &c: acting upon the the passive which are the Lungs themselves. The dilatation of the Thorax happens both in length and diameter; in length by means of the Lungs pressing upon the Diaphragm and thereby rendering its convexity more plane, the diameter is increased by the motion of the intercostal muscles &c: Thus the capacity Capacity of the Thorax is increased and as there is no vacuum between the Lungs and ribs allowed of in a natural state, the capacity of the Lungs will also be increased and there will be a vacuity in the Lungs wc. nature not admitting of and by the pressure of the Atmosphere rushing through the Aspera Arteria they are soon filled with Air making Inspiration. The fresh Air that is drawn in by Inspiration stretching the Bronchiae and stimulating the same cause them to contract and expel the Air making Expiration, some Authors imagine these are small Muscles between Between the cartilaginous Rings of the Bronchiae which they call Musculi Mesenchrondroeci serving to contract the the same in Expiration. The uses of Respiration are four, 1st For the circulation of the Blood, thus in Inspiration the Lungs are distended and the fine contorsions of the Arteries are are elongated so as to allow, blood to pass through them whereas in a collapsed state the blood cannot pass through them. in Expiration the Lungs collapsing push the Blood through the Veins into the left Auricle of the Heart. 2d. For sanguification by communicating the Blood making it more florid & denser 3. For cooling the blood 4th. For Vocification, exclusion of [illegible] &c: Of the Peritoneum This membrane is similar to the pleura, being smooth on one side & connected by cellular membrane on the other; it is reflected from the contained path to the containing. It makes a compleat bag 1st: covering the viscera by intimate connection, & then covering the abdominal muscles loosely on the inside. The peritoneum has been considered as a double membrane true or false, the last is no more than cellular membrane wch. connects the peritoneum to the external parts. We may conceive that all the viscera are behind or without the peritoneum, wch. running up on one side of a viscus is reflected back on another so as to form an almost compleat cover to each viscus separately, so that by a very nice dissection the peritoneum may be taken out in a compleat bladder having no perforation at all, leaving all the viscera undisturbed. Lecture 45th: Of the Stomach The stomach is a large muscular bag situate Obliquely from the Left Hypochondrium to the Epigastrium and serves for the reception of our food & digestion of the same, it has an upper & lower curvature called the lesser and greater curvatures of the stomach. There are two Orifices to the stomach; the superior one called the Cardia which enters it from the Oesophagus don't open at the fundus of the same but obliquely, at the side an inch or more from the end. Towards the inferior end the stomach grows smaller & turns up opening into the Duodenum by an Orifice called the Pylorus where there is J The Nerves of the stomach come from the par vagum. Is a partial kind of a valve which does not prevent the regurgitation of fluids into the stomach being only a thickness of the internal coat of the stomach. The stomach is furnished with Nerves and blood vessels. x Some Anatomists say there are small glands in the stomach, but if so they are not easily discovered, there is however a fluid discharged into the stomach from the extremities of the Arteries called the Gastric lymph from the gastros the Greek name for the stomach, there is likewise Lymphatics which absorb the redundant fluids & carrys it into the blood. The coats of the Stomach are three 1st. coming from the peritoneum and is called called the Peritoneal Coat. 2d. Muscular being composed of thin muscular fibres running longitudinal and transversely by which the capacity of the stomach is decreased the readier, to expel its contents. & 3d: Villous or internal Coat which is thin. Of the Intestines The first Intestine next the stomach is the Duodenum beginning at the Pylorus and ascending two or three Inches, has then two or three inflections pulsing down & across the Vertebrae — being all the way tied fast by a duplicature of the Peritoneum to the back, having no mesentery. The Ductus Choledocus & ductus Pancreaticus both enter the Duodenum several Several inches from the Pylorus, not both by one Orifice but by two very near together, next the Duodenum is the Jejunum, & then the Ilium which is the last of the small instestines. The coats of the Intestines are three the same as the Stomach, and in the small intestines are anular duplicatures of the internal Villous coat forming what is called Valvulae Coniventes which serve for two purposes, first to make the passage rough & prevent the Faeces, from passing on too fast and secondly to give more capacious origin. to the Lacteals The Ilium enters the Caecum not at the end but about an Inch there from obliquely the blind end only being Being called Caecum, where there is an appendage called Apendicula Vermiformis. At the entrance of the Ilium into the great Intestines, there is a Valve formed by the inner coat of the Colon & called Valvula Colli which in a sound state entirely prevents the regurgitation of the Faeces or any fluids passing, injected per Anum. The Colon runs up the right side then along under the stomach and down the left side, surrounding all the Abdomen, hence Clysters beside discharging the Faeces serve the purpose of a fomentation to the contents of the Abdomen. The Intestines are furnished with blood vessels from the two mesenteries except except the Rectum which receives its from the Hemorrhoidals. The Mesentery is a double membrane formed by a duplicature of the Peritoneum serving to connect the Intestines. & through which which the blood vessels go to be distributed to the Intestines, through it likewise goes the Lacteals which are fine Lymphatic or absorbent vessels arising from the villous coat of the Intestines and passing through the mesentery, they terminate in the Receptaculum Chyli, to be described hereafter, there is also a great number of Glands in the Mesentery through which the Chyle passes, and by which it is supposed to receive some alteration. These glands are very small. Lect. 46th Of the Lacteals & Thoracic Duct The Lacteals are an innumerable number of small vessels arising as before said from the villous coat of the Intestines & running through the mesentery in the duplicature of the same and through many fine glands and terminate in the Thoracic Duct serving to convey the Chyle The Thoracic Duct is a small canal running up the Vertebra of the Spine between the Aorta & Vena Azygos and under the Vena Cava until it gets above the Heart then it turns a little to the left and ascending empties itself in to the subclavian Vein. The lowest end of this Duct has been called Receptaculum Chyli but improperly as its no larger than the rest of the Duct neither do all the Lacteals enter there, but some higher Of Digestion Digestion is that change of the Aliments whereby they are filled for the nourishments of the body, this is different from the different juices mixed therewith and in the different parts of the body. The first change that happens to the Aliments is in the mouth by means of Mastication and mixing with the Saliva by which it is somewhat dissolved and fitted for more easy Deglutition Saliva is a clear mucous transparent fluid secreted by the Glands of the Mouth in the great plenty, and is of great use in digestion. After the Aliments is sufficiently masticated & mixed with the Saliva they are by the Tongue pressing against the roof of the Mouth forced into the Pharynx Pharynx and from thence through the Oesophagus into the Stomach. The Muscles employed in this act of deglutition are very many, serving chiefly to pull up the Oesophagus and to press the food down through the same, and we may very well conceive of the act of Deglutition by that of drawing a stocking on the Leg, part of the muscles drawing up the Oesophagus as we draw up a stocking upon the leg, and the rest pushing down its contents as we push down our leg into a stocking. The manner in which our food is digested in the stomach was by some of the Antients reckoned to proceed from heat K Heat, others reckoned it was performed by means of trituration, and others again from the different juices there mixed imagined it was performed by Fermentation, but modern Physiologists from many observations, think it is performed by all three jointly viz: Heat, friction and Fermentation. After the Aliments are sufficiently digested in the stomach, by the contraction thereof which is the beginning of the peristaltic motion of the Intestines, they are forced through the Pylorus into the Duodenum, where it continues some time and receives another change by having the Bile and pancreatic juices mixed therewith. The The Bile is an oily bitter, and attenuating substance endued also with a saponaceous virtue it will incorporate with Oils and when so mixed they are both soluble in water, it unites with salt forming a green color. by which it appears that the Bile is of great— use in attenuating the viscid part of the Aliments, and stimulating the— Intestines, the latter we are assured— of by this that Bile secreted and— discharged into the Intestines in too great a quantity causes a Diarrehea, and in a Jaundice where the Bile returns into the Blood and is not sent into the Intestines a Costiveness happens with while stools, and Boerhaave says Says the Gall of Animals is of use in this case to supply the want of Gall DeGraaf collected great quantities of the Pancreatic juice from Animals which he says is subacid it is reckoned to be somewhat of the nature of the Saliva, some reckoned it serves to sheath the Acrimony of the Bile but this in a natural state is not too Aerid These two fluids being mixed with the Aliments in the Duodenum the fluid and nutritious particles of the same are absorbed by the Lacteal vessels and by them carried into the Thoracic Duct to be conveyed into the Blood. These Lacteals are in all the intestines, but in the small ones in the Greatest Greatest plenty, That there are also Lacteals in the Colon seems evident 1st. From the rout the colon makes round the Abdomen, for if that is not for absorbing the particles that may chance to be not taken up by the vessels in the small Intestines why did it not go out strait like the Rectum and immediately terminate in Ans? 2. From persons being known to have lived a long time by Glysters, not being able to get any thing thro' the Oesophasgus, & it is known that they cannot pass by the Valve of the Colon. The contents of the Intestines are carried along by the Peristaltic motion thereof thereof. Vomiting is an inversion of the peristaltic motion and is performed by means of a deep inspiration which presses the Diaphragm against the stomach & a convulsive contraction of the stomach by which its contents are thrown up hence we learn that Emetics are good in Fluxes by inverting the peristaltic motion they stop the same. Of the Bile Bile is secreted in the Liver. It is 8 times as viscid as water. More subject to concrete than any other humour in the body. Its specific gravity to water is as 010 to 795. In a such quadrupeds & in the human species the bile is very bitter, but most so in carnivorous animals. Recent bile easily mixess with water. It mixes with oil by triture. Mixed with water it partakes of the property of Soap, dissolves oil so that it will mix with water & takes out grease spots. It dissolves resins & mixes with balsams. It dissolves Myrrh Bdellium & Wax like the yolk of an Egg, & is supposed to dissolve the Blood when mixed with it as in a Jaundice. The Ductus Choledochus may may be compressed & stopped by the Duodenum being distended with flatus. Eating Mushrooms has been known to distend the duodenum greatly & trangulate the ductus choledocus as it were with a ligature. It may also be obstructed by the contractions of the fibres of the intestine from stimuli as happens in the Colica pictonum, biliosa, inflammation of the duodenum, acrid purges, glass of Antimony & poisons. Hither we may refer the Jaundice in Infants which is removed by Rhubarb. Storck has seen the ductus choledochus obstructed with a cheesy coagulum. Hillary says this is frequent in the warm Islands. See Monro Ed: Ess: v. p 247 Baglivi prax: med: Haller tom: 6. p 590 x about 4 fingers breadth below the pylorus. Lect. 47th Of the Liver The Liver is a large Viscus situated immediately under the diaphragm mostly in the right Hypochondrium extending over the Stomach into the Epigastrium it is convex above and concave below suspended by three Ligaments one above to the Diaphragm one broad on the upper part of the round ligament from the Umbilicus which was the Umbilical Vessel in a foetus state. There are several fissures in the Liver 1st. Divide the great lobe from the lesser one. 2d. divides the Lobulee spigeli & the third where the Hepatic Vessels enter; The Vesica Fellis lies in a depness in between the two lobes of the Liver from where goes a duct remarkably contorted to appearance about two inches when it joins the hepatic duct, both of them united form the Ductus comunis Cholidochus which terminates in the Duodenum. x The Coat of the Liver comes from the L x sometimes called Tunica Glissoniana *The hepatic Artery divides a little before it enters the Liver one branch going to one lobe & the other to the other Lobe; it serves to nourish the liver & is said to secrete a small part of the Bile, some few of its evanescent frame has terminating in the pori biliarii as is proved by injections. The Peritoneum x beside which some Authors describe another coat wc. is scarce to be seen, The Gall Bladder has three coats 1st. from the Peritoneum, 2d: Muscular & The 3d. Villous, appearing like a honey comb inside. The Liver is furnished with Veins Arteries & Nerves. The Blood Vessels are the Hepatic * Artery & Veins & the Vena Porta. The Vena Porta is like an Artery first in its Office & 2dly. in the thickness of its coats; it arises from all the Viscera of the Abdomen terminating in the Liver and is supposed to carry the blood for the secretion of the bile, 1st. From the longness thereof & the smallness of the hepatic Artery. 2dly: By injections passing from it into the biliary Duets &c: It is certain however that the blood being carried into the Liver, part of it is converted x The general opinion of the ancient Anatomists was that the bile was conveyed into the Gall Bladder by little ducts running from the liver immediately into the bladder which they called ducti hepaticistics. Pechlin was the first who denied the existence of these ducts in the human body, then Ruysch, Cowper, Bidlow, Berger, Morgagni, Heister, Ludwig, Carsons, Lieutaud, Ceyer, & Cheselden. who says if a ligature be applied round the cystic duct, or if it be obstructed the gall bladder does not become turgid. Bohnius emptied the gall bladder of bile then tied a ligature round the cystic duct & upon examining the same several days afterwards found no bile in the cyst itself but the part of the duct between the ligature & liver was greatly distended. Bianchus & Haller have done the same. This clearly proves that there is no communication between the Liver & Gall bladder but by the cystic duct. What was supposed to be Hepatocystic ducts is demonstrated to be only blood vessels by Ruysch, Guntz, Haller Morgagni & others. converted into Bile & carried by the pori Biliarii which all meeting together form the hepatic duct though the hepatic duct to the cystic then regurgitates into the Gall Bladder; that the Bile regurgitates thus x into the reservoir is proved 1st. by there being no other passage though some supposed there was by little ducts wc. they called cysto hepatic ducts, but there is no such is evident from the injections not passing through that way into the Cyst, & in a Viper the Gall Bladder is vitiate some distance from the Liver. Horses & Deer have no Gall Bladder. That the Bile goes through the hepatic Cystic Ducts into the Gall Bladder is proved 2dly: by blowing into the hepatic duct the wind passes free into the cystic than through the ductus cholodochus. The remainder of the Blood is received by the Veins & carried back to the Heart Diseases x more frequently if not always the Jaundice arises from an obstruction of the Ductus communis Cholidocus An obstruction of the cystic duct alone will not occasion a Jaundice. Diseases of the Liver are: 1st. Hydatides these are of two sorts the first tumors composed of several lesser cysts filled with a gelatinous matter, the other a kind of vascular Cysts, the fluid circulating through it. 2d. Inflammation this is best relieved by plentiful bleeding warm relaxing and stimulating applications &c: It sometimes suppurates & even grows cancerous. 3d Scirrhi like other Glandular parts 4th. It gives origin to the Jaundice wc. proceeds from an obstruction in the Cystic x duct by wc. means the Bile is prevented from going into the Gall bladder and therefore returns into the Liver where it is absorbed by the Veins or lymphatic Vessels & carried into the blood & by that means tinges the shin, the cystic duct may be stopped by concretions tumors compressing the The same or more commonly by means of a stone lodged therein: a stone or concretion is best removed by Vomits which agitating the parts serves to remove it or by friction stimulating the same. Some have imagined that a Jaundice proceeds from a scirrhus Liver, but this is proved to not be the cause as no Jaundice can be unless the bile is absorbed after it is perfectly made Transient Jaundices sometimes happens to Children from a spasm of the Duodenum from acidities or otherwise hinders the Bile from passing therein & which is relieved as soon as the spasm is removed. Durable Jaundices happen when the Obstruction of the Cistic duct cannot be removed Lect. 40th: Pancreas is a long slender conglomerate Gland situate obliquely under the stomach between the spleen & Duodenum. each little x Haller supposes the pancreas secretes three times as much fluid as the salival Glands. * a costiveness and a pain in the region where this gland is seated is the common symptoms of its being obstructed. little acini or knot supposed to be the extremity of an Artery wound up in a knot and the whole vascular like the liver and all the other Glands of the body. from each acini goes a small excretion Duct which terminates in a larger duct in the middle of the Pancreas & called the pancreatic Duct & through which the pancreatic juice flows into the duodenum, the glands of the pancreas being the same with those that discharge the Saliva are supposed to secrete the same juice and for the same Use. x Diseases of the Pancreas are Inflammation, Cancer, & Schirri, which * are very difficult to be known until past cure they are however removed much in the same same manner as the same Diseases on other parts, Soap is a very good thing in this case which not only seen x This appears very reasonable though it was never taken notice of by any author before Mr. Monro. Is a good resolvent but supplies the place of this juice in digestion. Sometimes a Diarrhea happens in a Salivation and proceeds from a too great a secretion of the pancreatic juice which being the same with that of the saliva is supposed to be effected in the same manner with Mercury & is only to be removed by removing the cause. x Omentum is a fatty double membrane composed or formed by a duplicature of of the Peritoneum it has an appendage between the Liver & stomach called the Omentum minor & may be inflated. Uses of the Omentum are to lubricate & keep the Intestines warm, and it is supposed to supply oily particles to the Bile and also the blood. It is sometimes much distended with Fat and in very lean subjects quite reticular. Spleen Of the Spleen The Spleen is a roundish lobulated Gland situated in the left Hypochondrium it is furnished with blood Vessels and but very few Nerves. The Antients supposed its use was to counterbalance the Liver, others thought it contained a fluid called the Atrabilis, but the moderns mostly think that it is subservient to the Liver, it has been taken out of several animals without any apparent damage and is not therefore a vital viscera. It is subject to very few diseases, scarce ever being inflamed schirrius or cancerated, by reason of the fewness of the nerves, its only subject to a viscidity of its fluid and an enlargement therefrom. Lect. x The arteries generally divide into three branches and the vein into two before they enter the Kidneys. Lect. 49th Of the Kidneys The Kidneys are two Glandular bodies situate between the false ribs & Ilium. the situation of the right Kidney is somewhat lower than that of the left oweing to the Liver being on that side. The blood vessels of the Kidneys are an Artery and a Vein called Renales or Emulgents the right emulgent Artery is longer than the left & the left Vein than the right. These vessels enter at the Pelvis and are distributed through the same. x The external part of the Kidney is called Cortical the thickness of which is irregular and in this the Urine is secreted and emptied into little ducts in the inner part M x the pelvis is an enlargement or expansion of the of the upper part of the ureter where it enters the Kidney or rather where the united urinary Tubes regress out of it. part of the same, which is called the Mamillary part of the Kidneys. The little ducts into which the Urine is secreted are called Tubuli Urinarii and are in number about a dozen, these all unite in the Pelvis x forming the Ureter which is a membranous canal conveying the Urine from the Kidneys to the Vesica Urinaria. The Ureter as it enters the Pelvis of the Kidney divides into three parts one going towards each end and the other through the middle. The coats of the Kidneys are two, the first called Adipose and the second Membranaceous. There is an appendage to the Kidney called Glandula Renales or Gland Glandula Succentriari situate at the top of the Kidneys its particular use not known but supposed to be subservient to the Kidneys. Diseases of the Kidneys are, Inflammation, Diabetes from a too great laxness of the Vessels allowing the red particles of the blood to pass through them, gravel, Scirrhi &c: Lect. 50th: Of the Bladder The Bladder is a membraneous Bag situate in the Pelvis the upper part of which is covered with the Peritoneum but when it is very much distended it protrudes about an Inch above the Pelvis & being there covered with the Peritoneum Peritoneum & in this place is the upper Operation for the Stone performed by making an Incision into the Bladder without cutting the peritoneum the doing which would be of dangerous consequence. The coats of the Bladder are three, 1st: the common coat 2d: muscular and 3d: Villous, the muscular coat at the neck of the Bladder is thick & circular and is called Sphincter. The Ureters enter the Bladder one on each side about an Inch from the neck thereof by a small Orifice obliquely. The situation of the Bladder is between the Rectum & Olsa Pubis in men and between the Uterus & Pubis in women its use is a Reservoir to the Urine Parts of Generation Lect 51st 1st In a Male. These are the spermatic Cord, Testes Scrotum, Vesica Seminales, Prostate Gland, and Penis. The spermatic cord is composed of the spermatic Artery and Vein, Nerves, Lymphatics, & Vas deferens all included in acellular coat and some have supposed a muscular wc. they called Cremaster wc. is not visible except where it passes out of the Abdomen wc. it does in an oblique manner through the rings of the Abdomen, by which the Intestines and Omentum sometimes falls thro' forming an Herniae Inguinalis or Jerotalis along the side of the spermatic Cord The x Caput Gallinaginis The vas deferens empty themselves somewhat like the biliary ducts there being a passage from them immediately into the Urethra, but it commonly regurgitates into the Vesicula Seminales & there kept till used. Vesicula Seminales are two Glands situate under the neck of the Bladder, composed of little cells which communicate with each each other, being reservoirs for the semen, from each of these there goes a small duct which opens into the Urethra at the Caput Galaginis, x where is a large Gland called the Prostate Gland which secretes a fine mucus to defend the Urethra from the acrimony of the Urine. The Scrotum is composed of skin Cellular Membrane &c: next to which has been reckoned a muscle called the Dartos which is not to be discerned discerned, and the first obvious Coat is that wc. surrounds the Testicle much as the Pleura or Peritoneum does the contents within them this is called the Tunica Vaginalis propria Testes, and within that is a coat which adheres to the substance of the Testicle called the Tunica Albuginea, The substance of the Testicle is wholly Glandular, the spermatic Artery entering in at the side of the same and distributed through the same terminating in fine secretory ducts and these again in excretory ducts which uniting into one form the Vas deferens, The Epididymus is an Appendage to the Testicle formed by numerous convolutions of the excretory duct, reckoned 6 times as long as the Spermatic Cord. Lect. 52d: Parts of Generation in Females. These are either external or internal, the external are the Mons Veneris on which hair grows at a certain age Labia or External Lips of the Orifice at the upper part of wc. is a small body called the Clitoris under which in a small groove is the Iter ad Urinam thro' which the urine passes & into which the Catheter must be introduced in a suppression of Urine, & we should be well acquainted with this Orifice as the modesty of women often denies us a sight of the part, so that we must introduce the Catheter by feeling, at the lower part where the Labia unite is formed a Fraenum or Fushet or Foushette. x Iter externum ad Uterum Nymphae are two spongy bodies within the Labia within these in Virgins is a circular membrane called Hymen within these is the Iter externum ad Uterum x Vagina is a membranous substance furnished with rugae by wc. the Penis is more titillated in Coitus, there is likewise many small glands in the Vagina wc. secrete a liquor to lubricate the same and during the Venereal orgasm whether real or imaginary there is sometimes so much mucus secreted by these glands that it has been discharged, in great quantities so as to wet all the external parts, this by some is reckoned the Female semen. At the bottom of the Vagina is the Iter internum ad Uterum, the Os Uteri or Os Tincae. N Between x or young Puppy Between the Fushet and Anus, there is a seam called Perinaeum, this in difficult deliveries is sometimes lacerated by the largeness of the Foetus & it is necessary to prevent this accident for to support the Perinaeum with the hand while the Foetus advances Uterus is a small body situate obliquely between the Bladder & Rectum its coats size near half an Inch thick & its internal cavity very small; the Neck of the Uterus is full of rugae wc. serve to allow the same to dilate for the expulsion of the Foetus. The Os Tincae resembles the mouth of a Tench x situate at the bottom of the Vagina tho' not a continuation thereof the Vagina being inserted x An demande si le corps de la matrice etant renverse, & ayant tente inutiliment va induction, elle montroit quilque disposition a ve gangrener, e il conviendroit pour lors de l’eactirper, apris avoir porte une ligature le plus haut qu’il veroit possible. En parsil cas on ne devroit point balancer de faire cette operation pour empecker que la gangrene faisant du progres du cote des parties interieures, elle ne causat la mort a la malade. L'extirpation de la matrice, quoique rare, never sit point en cette occasion une operation temeraire, son succes etant prour a par plusieurs observations Verdeer's Anal: v: 22 p 66 Rousset, dans son Traite de Partes Caesares, dit qu'une femme a la suite de pluesieurs accouchemens laborieux, eut une precipitation de matrice qui ne pouvant etre inserted round the Os Tincae. From the Fundus of the Uterus there goes off nearly transversely on each side, a tube called the Fallopian Tubes lying loose & growing larger toward the further end wc. is fimbricated. The Uterus is suspended by the ligament lata & rotunda x Ovaria are two glandular bodies situate on each side of the Uterus inclosed in cellular membrane in each of these Ovaria are near 20 small Ova Of Generation This is perfomed per Coitus by the Male’s introducing his Penis into the Vagina, & perhaps into the Os Uteri tho' this is denied by some at which time the parts grow turgid by the venereal Orgasm the Os Tincae opens & receives the male Semen in which are Anamalcules, immediately attended. reduite, se gangrena, & tomba d’elle-meme. La femme ne daigna pas garder le lit, & elle Jouit d’une parfaite vante’ pendant trois ans, au bout desquels, etant morte d'uno fievre continue, louverture de fon corps fid voir que c’ etoit veritablement le corps de la matrice, qui par pourriture s’etoit s’epare de lui-meme Ibidem p168. afterwards the Os Tinca closes During the Orgasm the fallopian Tubes grow erect & the Timbria seize the Ovaria at wc. time some one or more of the Animalcule ascend through the Fallopian Tubes & enter the first ripe Ovum wc. has now burst the cellular membrane by its turgidity, then the Ovum is disengaged & carried by the Fallopian Tube into the Uterus, and the place where the Ovum was in the Ovarium is soon after filled up by a yellowish substance called Corpus Luteum, this I proved by opening a Bitch in the Hornes of the Uterus were 7 whelps in one three & the other four & in the Ovaria were the same number of Corpora Lutea, by alike experiment upon a Bitch opened while the Dog was fastened thereto, for dogs have no Vesicula Feminalis are obliged to remain fastened to the Bitch a a long time while the Semen is excreted and carried from the Testes by the Vas deferens into the Uterus I found that the semen was ejected immediately into the Uterus. Though the preceeding Hypothesis seems incredible and almost impossible, yet it answers all the Phenomena of Generation the best of any system yet advanced: however the subject is extremely intricate & no doubt is one of the Arcana natura which the omniscient Jehovah of his infinite goodness sees fit to hide from us. Lect: 53d. Of the Foetus its Nutrition &c. The Ovum of the female wc. is foecundated in the preceeding manner by the semen Masculinum is supposed to contact also the membranes that envelop the foetus with the Placenta, Umbilical Chord &c: The Ovum lies in the Uterus 9 months, but for the first two or three months the Placenta does not adhere to the Uterus The Chorionis the external coat of the Foetus it is a thick spongy membrane. The Amnios is within the Chorion it is very thin and smooth, between these two membranes some have described another called Alantois wch. includes the Urine of the foetus carried there from ye. bladder by the Urachus, this is found in some brutes but cannot be discerned in the human species The Placenta is made up of a congress of vessels. How does the Placenta adhere to the Uterus? How is the Foetus nourished? is it by the Mouth; the Umbilical Vein, or by both together? Does red blood go immediately from the uterine Vessels of the As first this want of Navel String, 2d: a diminution of the the Liquor Amnii, 3d. Mucus being found in the mouth & stomach & meconium &c: # 1st. A want of mouth or any passage into the chylopoetic organs, 2d a corruption of the Liquor Amnii 3d. That the liquor Amnii is an exudation from the foetus & consequently not fit for its nourishment &c: the mother through the Placenta to the Foetus & vice versa? from whence comes the Liqour of the Amnios? these are question, that have been differently solved by physiologists. Some have imagined that the placenta adheres to the Uterus by its vessels inosculating with those of the Uterus, others imagine there is no continuation of vessels by inosculation from the placenta to the Uterus, but that the placenta adheres thereto by a kind of cement; for (say they) if it adhered otherwise there must be a laceration (& consequently an inflammation & suppuration) wc. does not happen when it is bro.' away. As to the Nourishment of the foetus many have imagined that it rec'd. nourishment by the mouth & bring many arguments to prove it*, on the contrary others deny that the Foetus receives any nourishment by the mouth but wholly by the umbilical Chord - this is the most viewed Opinion, but for a particular acc't. of the Nutrition of the Foetus in Utero side Med: Essays of Edinburgh and Dr. Shippen’s Thesis for the connection of the Placenta to the Uterus A It was the rec'd. Opinion till of late by all who allowed the foetus to be nourished by the umbilical Chord that red blood was immediately conveyed from the mother to the foetus; Their arguments for it are 1st. that if the mother bleeds to death the Foetus will be deprived of blood also. 2d. Injections pass from the mother to the Foetus. 3d. that hemorrhages happen upon a separation of the placenta from the uterus. 4th that the umbilical Chord will bleed a great quantity when cut &c: but the most modern doctrine that now prevails & wc. answers all the phenomena best is that red blood does not pass immediately from the mother to the Foetus, for before the placenta adheres to the Uterus it certainly cannot, & then it must be nourished by absorption of the Placentine vessels as well before as after its adhersion to the Uterus; we have said before that the placenta does not adhere to the Uterus by inosculation of the Vessels, but by a slight cementation, thence we suppose that the the small ends of the placentine Vessels open into the mouths of the uterine ones, and as the mouths of the uterine Vessels are so large near the time of delivery as to admit a goose quill whereas the mouths of the placentine Vessels are so small as not to admit red blood its very probable there are many of the placentine vessels open into one of those of the uterus. These small placentine vasculae are part of them supposed to absorb the chylous & ferrous nutritious part of the blood in the uterine vessels which the placenta forms into red blood before it is conveyed to the Foetus; The manner how the placenta acts in forming this nutritious fluid into blood is unknown, but it is supposed to perform the office of Lungs in that particular. The placentine vessels having absorbed the nutritious particles of the mother’s blood and and the placenta formed it into red blood it is conveyed by the umbilical Vein into the Foetus, for its increase & nourishment, while the superfluous & unnutritious part is reconveyed by the umbilical Arteries into the placenta & is absorbed by the uterine Vessels and mixed with the blood of the mother; thus instead of a reciprocal circulation between the Foetus & Mother which was formerly Supposed, and is still by some, there is only a secretion of the fluids which pass from one to the other. The Arguments brought to Support this new doctrine are, 1st: That upon the mother’s bleeding to death, the Foetus will not be deprived of any of its blood this Dr. Shippen proved by an experiment he made in Edinburgh before Alexander Monro jun'r he bled a Bitch to death then opened her and took out her whelps which appeared to have lost not one drop of blood blood. 2d. That the umbilical Cord when cut will not bleed but very little, no more than the blood contained in the Placenta, this most Midwives know & it is mentioned by Smellie: but 3d. Lastly the greatest argument of all is that Injections cannot be made to pass from the placenta into the Vessels of the uterus nor vice versa tho' it has been repeatedly tried by the greatest Anatomists notwithstanding what has been said by some to the contrary. A Course of Bandages Bandages are very necessary to confine dressings upon any external part of the body, injured either by accident or by a necessary Operation. Lect: 54th: Bandages of the Head. 1st: Handkerchief doubled & made 3 square put round the head & tied behind 2d: Grand Covre Chef a large square handkerchief doubled to ab.t 2/3 the way & laid on the head the single part so as to reach the Nose, the double part the forehead, wc. double part being uppermost must be fastened under the Chin, the other then turned up & tied behind in the nape of Neck 3d: Poormans Bandage of Galen a piece of linen cut into 6 tails & laid on the top of the head, the middle tails fastened fastened under the Chin the hind ones before & the fore ones at last behind. 4th: Capaline a long doubleheaded bandage 4 or 5 fingers breadth wide to put round the head 5th: Uniting Bandage double headed & like the former with a slit near the middle to be applied to a wound of the forehead. 6th: Scapha for bleeding in the frontal vein going several times round the head at last the first end turned over & tied behind 7th: Kiaster double headed for bleeding in the Temporal Artery going several times round the head then twisted round to a hard knot over the Orifice & then part one end over the crown the other under the Chin and fastened. 8&9 Monos- & Bi-Ocular double headed the first covering one Eye the last both Eyes Lect. Lecture 55th: 10 Accipiter a T Bandage for the Nose going round & tail tied over the head. 11 A four tailed sling bandage for the upper Lip. 12 A four tailed sling bandage for the Chin the under half being the broadest. 13 Capistrum double headed bandage passing from under the Chin to top of the head then to neck & round to the Chin &c: 14. Divisive along double headed rowler to keep up the head. Bandages of the Trunk 15 Spica double headed for the shoulder 16 Star Bandage for a fracture of the Clavicle a single headed rowler & if necessary the Capaline may be applied with it for greater safety. 17 17 For the Thorax the Jenriette or Napkin & Scapulier the first going round the body the latter slit going over the head & fastened thereto. 18 Suspensor of Heliodorus for a diseased Breast a X bandage 19 For Paracentesis a broad flannel roller to go round & compress the Abdomen. Lecture 56th: 20 Spica Inguinis double headed for any disorder in the inguen. 21 T Bandage or Suspensor Scroti beside wc. there are several others of less note to these parts particularly the Truss Bandages of the Extremities 22 Deloer for the Wrist 23 Spica Pollicis for the thumb. 24 Gauntlet ~ } for the fingers 25 Denigantlet 26 26 Eight tailed bandage for a broken Patella &c: 27 For a simple Fracture Thypodesmus going round under the splints a single headed roler & Epidesmus going over the splints one roler very long may serve for both. 28 For a compound Fracture where there is a Wound &c: the 18 tailed bandage together with splints Tape &c: and lastly Junchs, Box, or Cradle &c: if it is one of the Legs. A Course of Operations Lecture 57th:~ Of Sutures There has been many sutures invented most of which are out of use. We ought to observe that a wound made longitudinally in the direction of the ~ Fibres requires no sutures be it ever so great, for by means of a bandage the sides of the Wound is easily brought together without suture. But a wound made obliquely or transversely requires a suture as no Bandage can be made to keep the wound together. The intention of Sutures is to bring the likes of a fresh wound in apposition, that the vessels may inosculate & heal by the first intention, the chief sutures are The Glovers stitch, The interrupted suture, The quilled suture, & the Gastroraphy, The Glovers stitch is performed with a strait needle & waxed thread single, turned over and over. The interrupted Suture is made with a crooked needle & single waxed thread the lips of the wound being brought together first make a stitch in the middle the Rule for which is to begin as far from the edge of the wound as the wound is deep making the needle come out at the bottom of the wound & continued thro' on the contrary side then tied not over the wound but on one side, then make two other stitches near each end wc. is mostly sufficient. Quilled Suture is made with a crooked needle as before with a double cord & tied at the end with a quill on each side the Wound. The The Gastroraphy is performed when the parietes of the Abdomen & Intestines are cut. The intestine is to be saved up with the Glovers stitch leaving a piece of the thread at each end to lie out of the wound of the Abdomen, then the Parietes is to be stitched with the interrupted Suture in a particular manner viz: on each end of a waxed cord must be put a crooked Needle, then take one needle & from within the wound push it out then take the other needle & do the same on the other side of the wound, bringing them together & tying the same, do so until you have as many stitches as you think is necessary Of Trepaning When it is necessary to perform this Operation we should consider first the places where the Trepan may be applied; there are 3 places where it is improper to apply it viz: to the Sagital Suture, the frontal Sinuses, & the Os Accipitis. In Operating, an Incision must be made of a good length through the scalp, the same opened & the Cranium scraped, than having fixed upon the place apply first the perforator & after that the Trepan secundum Artem. Of Fistula Lacrymalis This operation is performed when the ductus as Nasum is stopped & has formed in the Lacrymal Sac &c: Sometimes compression alone will cure this disease but when the Operation is necessary its performed by making an incision over the Sac at the bottom of the Orbit & half the length of the same, into the Sac & cleaning out out the matter & if necessary making an Aperture through the Os Unguis with a strong Probe or a Trocar into the Nose. Of the Polypus of the Nose This is an excrescence growing in the Nose in the Schneiderian Membrane, has different degrees of firmness, in a recent state it is very tender but by degrees grows harder until it gets to a great firmness; the best time for extracting it is when its so hard as not to break easily with the Forceps but not so hard as to adhere to the Schneiderian membrane too strongly. Its extracted by taking hold of it with the polypus Forceps & working it to one side and the other backwards & forwards &c: until it is loosened. Extirpating the Tonsils. This is best done by Ligature for fear of an Hamorrhage if the Tonsils are largest at the apex its an easy matter with proper Instruments to pass the Ligature round its basis & make it tight, but, it often happens that the Basis is largest in this case a ligature put round woud slip off therefore with a proper needle it must be run through the middle of the Tonsils & tied on each side cum node Chirurgica &c: Of Amputation Amputation is sometimes necessary but not near so often as has been thought; all agree that it is necessary in a Mortification, but then it must not be performed until the mortification is stopped & even new flesh begins to granulate. In Amputating the Leg we must stand between the legs that the saw may take the Fibula before the Tibia is quite cut off. we We first apply the Tourniquet to the thigh to stop the blood, then with a strait knife wc. is the best we make a circular incision with two cuts round the leg or thigh through the skin cellular membrane & fat about an Inch below where we intend to cut off the Bone, then an Assistant must pull up the skin as high as possible, after wc. the Operator must make a second Incision through the muscles to the bone then if it’s the leg or forearm the double edged scalpel must be run between the bones to cut the interosseous Ligament & Muscles, lastly the bone itself must be cut off with the saw. & then the Arteries taken up &c: The Fingers are Amputated contrary to all other parts at the Joins by cutting the flesh as before then stretching it up & with the scalpel beginning on the side take off the Joint. Of Empiema This is an operation for letting Pus Water or Blood out of the cavity of the Thorax, oftenest Pus, wc. comes from an inflammation & Suppuration, when this is in but small quantities, the Lungs by then great power of Absorption often carries it off by Expectoration as we see in Pleurisies; but when in great quantities the operation must be performed very carefully for fear of hurting the Lungs between the 6 & 7 or 7 & 8 Ribs with a common scalpel. Of Bubonocele This is the dangerousest operation in Surgery, & not to be performed but when absolutely necessary; when so it is done by making a long incision from above the rings of the abdominal Muscles almost to the bottom of the scrotum carefully in to the Intestine thro' the Peritoneum or Herniary Sac then dilate the passage by incision & carefully reduce the Intestine. Of Couching This Operation is performed for the removal of a Cataract or opacity of the crystaline Lens; there are two ways of doing it, the old way of depressing the Lens with a needle to the bottom of the Eye into the vitreous humor wc. is done by running the needle abt. 1/10 of an Inch below the Cornea into the posterior Chamber behind the Iris & depressing the Lens. The other method, wc. is the new way, much in vogue at present, & I think the best is to cut the Cornea & extract the the crystalline Lens. In the Old way the Lens is very apt to use after it has been depressed wc. makes this new way preferable; it is performed by a small knife with but one Edge wc. is to enter near the place where the Needle enters & pushed thro' into the anterior chamber above the Iris (taking care not to cut it) and out on the other side cutting half or better of the Cornea, then with the point of the knife cut the capsulae of the Lens & its easily pressed out. Of Lithotomy This Operation is performed for extracting a stone out of the Vesica Urinariae; there has been several methods invented to perform this operation but the Lateral Operation or that invented by Irene Jaques is the best & universally in use. We are not to operate until we are certain there is a stone in the Bladder & we can feel it by sounding & all the other Surgeons present. In Operating we first tye the patient on a Table of a sufficient height lying on his back by making a noose with a garter round the Wrist then making him take hold of the bottom of his foot with his hand putting the Garter round his Instep & hand in form of 8 a sufficient number of times, with an assistant to hold each knee then introduce the Staff into the bladder, letting a careful assistant hold the same bending the top a little towards the right Groin is as that the bend of the same may turn a little to the left then then the Operator setting down right before the Patient must with a sharp scalpel make an incision immediately upon the staff from the Base of the scrotum to beyond the anus abt. an Inch to the left of Cerines through the skin & fat, (this should be made thus large that we may get at any Artery if necessary) then make the incision shorter down to the staff when we feel the staff bare we must take the Gorget put the point of it into the Groove of the staff then take hold of the staff from your assistant & turn it over while you slip the Gorget along the groove into the bladder, then take out the staff, & introduce the Forceps upon the groove of the Gorget, when they are in the Bladder pull out the Gorget & gently feel for the stone, when you find it take care to get good hold of, it not being in too big a hurry; when you have it fast extract it. If the stone breaks take out what you can with the Forceps & the rest with a scoop. The wound must be drest gently wth. dry Lint. Med. Hist. MS. B 158 Of Tapping Of Injections The ancients used to employ only Ink for Injections (which answered the end but very poorly) until the time of Ruysch who made his injections of wax, some of wc. have since been improved; his method of Injection was as follows viz. He first laid open the hypogastrium & made two incisions about an Inch long into the Aorta & Vena Cava, then put the Subject in cold water several days pressing out the blood frequently. Next he put them in warm water several days more & put two tubes in the Artery one upwards & one downwards & fastened them tightly. His injection was only simple Suet calomel with Cinnabar in cold weather & in the Summer time he added a little white wax & injected it gently when warm into the vessels, then put the Subject into cold water till the injection was cold, then dried the preparation carefully or preserved it in spirits of wine Injections used by the modern are the follg: Corroding Injection of Dr. Nicholls Rx Wax 4 ounces Resin 3 ounces when melted add Turpentine Varnish 3 ounces Dr. Hunter's Corroding Injections Rx Wax 3 ounces Resin 3 ounces when melted add Venice Turpentine 11 ounces Another Rx Wax 4 ounces Resin 3 ounces when melted add Oil of Turpentine 2 ounces Another Rx Wax 4 ounces Resin 8 ounces or 10 ounces Tallow 3 ounces melt them together The Injection is known to be of a proper consistence by dropping some of it when melted in water & when thoroughly cold forming it into the shape of the Vessels if upon Landing it breaks it is too hard if it bends easily it is too soft & must be mended. Those Injections which have Turpentine Varnish, Venice Turpentine or Oil of Turpentine in them must be tried as above every time they are heated because in heating they loose of their volatile oil Of the Colours To the foregoing Injections such a quantity of colouring matter must be added as will give them a bright colour which must be determind by the Eye Colours generally used are Vermillion Kings Yellow, Blue Verditer & Flake White. Other colours may be used. They are generally to be mixed with the Injections when they are melted; but there are some objections to this rule in some of the colours particularly the blue Verditer & in some measure the Flake White for Navy both ferment when mixed with the foregoing Injections; to prevent which it is necessary to melt some of the Ingredients alone & add the colour to it before the other Ingredients are added. The following Experiments will particularize these Exceptions 1 Blue Verditer with Tallow alone causes no Fermentation 2 Blue Verditer with wax alone don’t Ferment 3d. Blue Verditer with Resin alone does ferment, therefore mix the blue Verditer with the Tallow or Wax alone or together & afterwards add the Resin which causes a small froathing If Turpentine Varnish, Venice Turpentine or Oil of Turpentine be used mix your colour first with the melted wax & then add either of these Ingredients with the Resin These observations are equally true of the Flake White When we make a white Injection instead of yellow Wax we use white. It would seem that we have not yet any Green Colour, but as blue & yellow make a Green the blue Verditer added to the yellow wax or Resin gives us a fine green Dr: Nicholls fine Injection Rx Hard Brown Varnish & hard White Varnish a 5 ounces Turpentine Varnish 2 ounces add the Colour & shake the Vial first putting some shot therein to make them mix. Either of the hard Varnishes will do as well as both adding the same proportion of Turpentine Varnish viz 1 to 5 Another Rx Hard Brown Varnish & hard White do. a 8 ounces Venice Turpentine 2 1/2 ounces mix these as the former If we neglect being nice in our proportions or from often heating these Injections become too hard or Brittle. We know when they are of a proper consistence by the following Experiment; Drop one drop of it upon cold water which will immediately diffuse itself over the whole surface when the spirit will be immediately attracted by the water & the gums with the Turpentine will be left swimming on it, if this will bear raising up without breaking it is of a proper consistence, but if it breaks its too hard & much be softened till it is properly tenacious Of Watery Injections Glue dissolved in water alone makes a good minute Injection; before it is dissolved by heating its necessary to steep it in water for 12 hours then boil it upon the fire till the whole is dissolved, afterwards strain it & drop some of it upon a cold stone or any cold substance to cool that you may know its consistence; when it is somewhat thicker than a common gelly it is of a proper consistence Isinglass & water prepared in the same manner as the preceding ~ makes an Injection similar to it Gum Arabic, Tragacanth, or any of mucilaginous Gum dissolved in Water to the consistence of Cream & strained as the preceeding make a very minute Injection As the Colours mix difficultly with with these watery Injections, they ought first to be mixed well with a little of the Injection & then the remainder added to it. Of Oily Injections We often make Injections of almost all Oils as Oil of Turpentine Hogs lard Tallow &c: The oil of Turpentine is rather too thin of itself but when added to two parts Tallow is a good Injection Butter or Hogs Lard make of themselves a pretty good Injection All fine Injections require more Colours than coarse ones, for as it is to run into much smaller vessels it of course becomes more & more transparent and therefore requires such a quantity of colour as to render it opaque even when it is most minutely separated on diffused within in very small vessels or on any surface Of Common Injections The corroding Injections are too hard for several purposes & the fine ones too soft therefore we need something between them, some of which must be softer than others The hardest is Rx Resin 3 ounces Tallow 2 ounces Wax 1/2 ounce Colour sufficient for an Injectn. is Rx Resin 2 ounces Tallow 2 ounces Colour sufficient for an Injection These are generally used when the part is intended to be dissected Varnishes Turpentine Varnish Yellow Resin 14 lbs Oil of Turpentine 16 lbs, boil the water out of the Resin & then add the Oil of Turpentine from the fire. White Hard Varnish Mastich & Gum Juniper a 1 grain Alcohol 8 grains ~ Brown Hard Varnish Shell Lac & Seed Lac a 1 1/2 grains Gum Juniper 1 1/2 grains Alcohol Galls. 2 clean the Gums from dirt & bruise them pretty small then put them in the spirits & dissolve them in a Sand heat The Spirit of Sea Salt is the corrosion commonly used by Anatomists The part to be Injected must be macerated in water blood warm 2 or 3 days so as to relax the vessels & soak out all the blood in them, then having a proper sized Syringe with pipes of different sizes, fit one of the pipes into the vessel & fasten it well with a ligature bringing the ligature round the cross piece to secure it the latter. The part to be injected lying in the warm water & the Syringe and Injection being warm, the Syringe is to filled with the Injection, the end of it put into the pipe & kept fast & the Embolus of the Syringe pressed gently down with the breast till the part is sufficiently injected or the syringe when it is to be filled and emptied as before if necessary ~ Med. Hist. MS B 158 Med. Hist. MS. B 158 Ex Libris Jonathani Elmer Ipromet manu Jeripris Jonathn. Elmer’s A Course of Anatomical Lectures Delivered By Dr. William Shippen junr. Professor of Anatomy & Surgery in the College of Philadelphia Anno 1766 Quanta autem existerent consilii solertissimi indicia, su tota hominis fabrica perspecta foret? si corporis totius species et dignitas? Sensuum organa subtillissime fabricata, et aptissime locata. Synop: Meta: Anatomia fundamentum est Medicinae Anomal Anatomical Lectures Lecture 1st: Anatomy avatouia in Greek signifies cutting & by it antiently was meant only the dissecting of bodies, but at present it is implied in a more general sense. Anatomy in respect of its object is divided into human and comparative. Human Anatomy is that which is employed on the human body; and comparative Anatomy is that which is employed upon the bodies of other animals, these serving for the more accurate descriptions of several parts, and supplying the defects of human bodies. Anatomy from its various ends may be said to be of four kinds viz: Theological, Medical, Juridical, and Judicial. The The first consists in an acquaintance with the works of the creator in the human frame; according to Fontanel the study of Anatomy & Autonomy afford the strongest arguments against Atheism. Medical Anatomy is ultimately health, for the presentation of which, restoring it when impaired, by diseases, or even preventing their access, nothing surely is more necessary than a true knowledge of the structure of that frame so liable to be injured. Juridical Anatomy is the determining the causes of suspicious deaths, impotency, barrenness, the true times of pregnancy and delivery, the mortality of Wounds and a multitude of other causes of great importance to be adjusted in account of Judicature. Judicial Anatomy is the determining the cause and manner of the death of diseased persons from a subsequent dissection of the body body; this is of the utmost use in the practice of Physic. Upon the whole then the use of Anatomy in very great, nor is it confined to the bounds of Medicine alone; the Philosopher and Theologist, the Magistrate, Painter and Sculptor are in their respective employments more or less qualified in proportion to the progress they have made in this science; but the physician and Surgeon are the people to whom it is most immediately necessary and who without a perfect knowledge of it cannot do justice to the world in their professions. What the needle is to the mariner, Anatomy is to both these, and we may venture to say that without its assistance, they would be rather detrimental than beneficial to mankind. The Anatomy of the solid parts is by Heister called Osteology and that of the soft parts Sarcology, each of these are subdivided. Osteology or the anatomy of the Solid parts is divided into the anatomy of the Bones called Osteology; Chondrology or the anatomy of the Cartilages; and Syndesmology or the anatomy of the Ligaments. Sarcology or the anatomy of the soft parts is divided into Dermatology or the anatomy of the Teguments; Splanchnology or the anatomy of the Viscera; Myology or the anatomy of the Muscles; Neurology or the anatomy of the Nerves; Angiology or the anatomy of the Veins and Arteries and Adenology or the Doctrine of the Glands. In the human body as a complex hydraulic machine a double inquiry must be made 1st. Into the structure of the parts, this is called Anatomy, 2d. Their functions & the laws of their motion which is termed Physiology Lecture 2d. As the solids are formed out of one principal fluid chiefly, called the Blood it is proper to begin therewith. Of the Blood Blood in Scripture is called the life of the Animal; according to some it is the primum vivens ultemum moriens, its a heterogeneous mass, as is evident from the variety of ingredients of which it is made up, and the various forms it assumes in the animal machine. The blood is composed of three substances viz: Serum, Gravamentum & a coagulable Lymph: We shall consider these in three different manners; first when ocularly examined, 2d. Viewed with a Microscope, and B 3dly: The chemical Analysis thereof. Blood fresh drawn from a sound living animal, upon landing, part of it congeals into a hard coagulum suspended in a yellowish Serum, the upper surface being of a florid color while the bottom is black; the reason of the blood appearing bright and florid at the top is from its being in contact with the Air; this is confirmed by an experiment of Dr. Hunter’s who put a quantity of blood fresh drawn into a vial, & stopt it close; upon standing it all turned of an uniform black color, except a little spot upon the top with which a globule of Air had got in contact. Blood stirred round with a probe whilst Whilst warm, a fibrous elastic substance is obtained, which, put in water turns of a whitish color; this is the coagulable Lymph, is strongly elastic, & is the cause of cohesion in the particles of the Blood, as is evident from the extravasation of the blood after death by dissolution of the cohering particles. The coagulable Lymph is sometimes discharged from the Uterus and by Nurses taken for an Abortion; this error they are sometimes led into from a desire that it should be so. If spirits of Wine be added to Serum, or the same made boiling hot, it rises up, emits fumes, and turns into a coagulum similar to the White of an egg: the fibrous part of the blood is what forms Polypuses Polypuses concretions &c: Blood viewed by a microscope appears to consist of a number of globules, the larger ones being those that tinge it of a red color, &c: therefore chiefly make the crassamentum, are of a certain determinate magnitude being of the same bigness in all animals, in a Sheep as in an Ox, in an eel as in a man. These globules are composed of six smaller or ceruminous ones; and these ceruminous ones are composed of smaller or lymphatic ones; and it is probable there are still lower orders of globules of blood. These globules of blood are of a lenticular form and elastic the largest kind being less than the 1/3000 part of an inch Inch. the crassamentum is supposed to contain 1/3 of the mass and the Serum to make up the other 2/3. Blood chemically analyzed; upon distillation with a slow fire a quantity of Phlegm arises, with the fire increased next arises an Oil and a volatile Salt, the caput mortuum being a fixed alkali and a cretaceous Earth. The chemical proportions of the blood are by Dr. Martin & Boyle recvd. as follows viz: of Phlegm 5/6 of Oil 1/15, of Salt 1/25, of Air 1/20, & of Earth 1/75, part of the whole mass. The specific gravity of the blood to that of rain water is by Dr. Jurin and and Martin reckoned as follows, by Jurin as 1000 to 1054 by Martin as 1000 to 1056 or 1057 or as 10 to 19. The density of blood in living animals is to its density when reduced to the coldness of temperate Air as 134 to 135 or 992 1/2 to 1000. The color of blood is for the most part red, but redness is not a constituent quality in blood, for some Animals have white blood. In the human body the blood is redder & more florid in the Arteries than in the Veins, oweing to the action of the Lungs upon it, for by shaking fresh blood in a vial taken from a vein, it appears of the color of arterial blood. That the blood is is reder in the Arteries than in the Veins. Dr. Hunter proved by the following experiement: he opened the Thorax of a live Dog and kept his Lungs working with a pair of Bellows; and drew a spoonful of blood from each side of the Heart is, from the Vena Cava & Aorta the latter of which appeared the reddest. From the accurate experiements it is found that a cubic inch of rain Water weighs 253 1/3 grains, a cubic inch of warm blood 264 3/4 grains. An Ounce of Blood contains 1,813 Inches, an avoirdupois ounce weights 437 1/2 grains equal to 1,727 inches of water and 1,6526 of warm blood. Lect. *Among these we may reckon Boerhaave instit. vol. 2 the colour of the Arteries are of aligamentous substance and not muscular as is evident from their white appearance and their of elasticity both of which is contrary to the general characteristic of a muscle however we are informed that Dr. Cullen has lately discovered that there are muscular fiber in the coats of the arteries the action of which he thinks assists in propelling the blood onward. J. Cullen likewise says that there is a muscular coat to the arteries as well as Boerhaave & many others. &c physiology [illegible]. Lecture 3d. Of the Arteries & Veins An Artery is a strong, membranous, ramifying, elastic Tube, endowed with pulsation; arising from the left side of the Heart, and terminating in every part of the body. The Arteries are composed of three coats, tho’ some have reckoned four and some five.* The first external coat is very thin the fibres of x which going longitudinal & circular; the second coat is thickest and the fibres of it go in a circular direction; the 3d. coat is very compact and its inside very smooth and even, this smoothness and compactness of the inner coat serves two purposes. 1st. to allow the blood to to pass without hindrance & 2d. to prevent its exudation. The pulsatory motion of the Arteries is a dilatation and contraction of them; the former called Diastole, and the latter Systole, which precedes proceeds from the Heart, besides which they have a sort of aperistaltic motion, as is evident from an experiement of Dr. Hunter’s, who opened alive Dog and cutting off the mesenteric Artery, injected it wth. a warm milk, which he could plainly perceive the Artery to carry along wth. a vernicular motion; to confirm is the more he injected the mesenteric Vein but the milk went no farther than the & the force of the injecting propelled it. There are but two Arteries in the body viz: the pulmonic, which carries the blood through the small circulation, and the Aorta, which carries it to all the parts of the body. The coats of the Arteries are very elastic, and are furnished with blood vessels for their nourishment; the Arteries mostly and all except the Epigastric ramify at acute angles. The commonest diseases the Arteries are subject to, are, Aneurisms and Ossification. Aneurisms proceed from a preternatural dilatation of the coats of the Artery’s and are of two kinds 1st. When the blood is x it is sometimes found in young subjects and is oweing perhaps to a disposition of the constitution to form bony matter. is contained within the coats of the Artery. 2d. when the Artery is burst & the blood extravasated into a membranous bag. Ossification happens mostly to Old people from a weak & slow circulation of the Blood. x Veins are elastic, ramifying Tubes, like the Arteries; except smaller. their coats thinner, and without motion. Phisiologically speaking the Veins begin at the extremities of the Arteries, or more properly speaking they are a continuation of the Arteries reflected back toward their Origin the Heart; but anatomically speaking the Veins arise from the Heart. There There are 7 Veins in the body from which all the rest arise viz: The 2 Venae Cava ascendans and decendans; 4 pulmonary Veins (two from each lobe of the Lungs) and Vena Portarum. The veins are mostly ramified in the same manner as the Arteries, exct. the Vena Portae, and the cutaneous Veins of the extremities, & other parts. The veins of the extremities have valves, but not those of the Viscera; the reason of which is because there is no Muscles in the viscera; hence the use of those valves in the Veins of the extremities is to prevent the blood from going backward as well as x Bellini especially is of this opinion as well as for, to push it forward when the muscle is contracted and the Vein compressed. Of Venesection & Hemorrhages. In bleeding, the blood is supposed to x flow out faster at the orifice than it circulates in common, and to increase the circulation to the part, hence the doctrine of revulsion & derivation is easily understood; thus we find in a Cephalalgia bleeding in the foot causes a derivation to the feet and a revulsion from the Head &c: In Hemorrhages the antients used Ligatures round the joints, wc. stopping the return of of the blood to the Heart checked its impetus, but but by Venesection his ends are answered: e,g, supposing an Hemorrhage at the Nose, Lungs, Uterus &c: bleeding takes off the impetus of the blood & causes a revulsion, at the same time. Dr. Haller thinks this latter method much the [illegible] the Veins are some of them subject to Varices, which are an obstruction, or destruction of the valves thereof. The muscular coat of both the Arteries and Veins are somewhat subject to inflammation & suppuration, but not near so much as the other muscles of the body; this is very wisely adapted to their function, for suppuration of their coats would be attended with fatal consequences often. Lecture Lecture 4th. Of the Lymphatics. Lymphatic or absorbent vessels are those fine ramifying vessels which contain a clear diaphanous Liquor; they take their rise internally from the cavities, as the stomach, intestines, and externally from the surfaces of the skin. The antients supposed the Lymphatics were a continuation of the Arteries dividing them into three classes, sanguineous, venous, and Lymphatic, but, it has very lately been discovered that the Lymphatics are an entire system of vessels by themselves, having no affinity or communication with either the arteries or veins. this This is proved 1: by injections not passing into them from the arties 2: by the motion of the fluid in them and the valves they have; they are called absorbents from their office, which is to absorb the Lymph and other matters and carry it into the thoracic duct or Receptaculum Chyli; where they are all supposed to terminate. Those vessels called lacteals belong to this system; and called Lacteals only, from their carrying a milky chyle: their origin termination and course of their fluids being the same. That the lymphatics are absorbents is evident from their absorbing moist substances rubbed on the skin, as Mercury, Turpentine, Garlic &c: but in a more obvious manner in the venereal Disease, where absorbing D the virus they carry it to the adjacent Lymphatic Glands and cause them to tumify, hence Buboes &c: sometimes the virus causing the glands to tumify and inflame, constricts the vessels beyond the same and prevents the infection from going any farther; hence the cure of the venereal disease sometimes by the suppuration and discharge of a Bubo. Of the Glands. A Gland is a secretory Vessel — the antients called only those Glands which we feel hard movable kernels under the chin and other were until Malpighius by his microscope found the Liver and other substances to be of the same texture, and therefore termed them all Glandular. A A Gland he thought to be made up of little fine round bodies consisting of Follicles which contained the secreted fluid and between which was a parynchemical substance; but Ruysch by his injections found that the Glands were vascular or made up of fine vessels which has been further confirmed by later anatomists. The vessels of the Glands are Arteries, Veins, secretory and to some excretory Vessels Nerves & lymphatics Of Secretion Some have imagined that the secretions were performed by the diameters of the secretory vessels, supposing them to be of the size of the particles secreted; but this theory is subject to these two objections, viz: that the smaller particles will will go off with the larger ones and to the secretion be confounded and in a Jaundice, when once the Bile had got into the Blood it would continually remain [illegible] & the Jaundice could not be cured; others supposed a particular fermentation happened in the veneral glands, & from thence arose the difference in the veneral secreted fluids, and likewise was the cause of the secretion; this theory is liable to the same objections with the former, and therefore the most received opinion is, that the secretions depend upon the particular disposition of the vessels, to the particular fluid it is to secrete; hence arises these Axioms. 1st. That the secretions are carried on uniformly in a living sound Animal. 2d. One secretion increased another is diminished &c: Lect. Lecture 5th. Of the Muscles & Tendons. A Muscle is a fleshy, fibrous, [crossed out] substance, consisting of Veins, Arteries, & Nerves; besides fleshy fibers &c; having more nerves in proportion than another part of the body serving to give notice to the brain of any external stimulus or irritation. The redness of the muscles is not inherent in the fibres thereof, but only oweing to the blood contained in them, of which there is a great quantity, more than is sufficient for their nourishment and may possibly be subservient to their motion. A Tendon is a white compact fibrous unelastic substance. most muscles terminate in Tendons, and the Tendons are by some reckoned a continuation of the fibres of of the muscles to which they belong, only more compacted together so as not to admit the red globules of blood between their interstices: but Dr. Hunter thinks the fibres of the Tendons are not a continuation of those of the muscles, but distinct fibres someway cemented thereto. The muscular fibres are cemented together by the cellular membranes and an intervening glue, & serve for the moving of the solid parts of the body. The Tendons are for the better insertion of the muscles, and of great use in motion; eg: in the Perforans and Perforations of the hand, the muscle arises from the inferior part of the Humerus, and if that was continued down to its insertion muscular, it would render the hand troublesome some and unwieldy, whereas now, the Tendons, being compact & taking up but little space, remedy that inconvenience. Round many of the Joints as the Wrist Ancle &c: there is a capsular Ligament or Frenum which serves to keep these tendons in their right places, and facilitate their regular motion; likewise over some of the Muscles there is a tendinous expansion called Aponeurosis, of much the same use as the preceding Ligament. The muscles may be reckoned of three kinds first Oblong as those of the Arm, 2d. Convex as those of the Heart, Stomach, Bladder &c. 3d. mixt as those of the Abdomen the Pectoral muscles &c: Muscles have their names from their Origin, Insertion, Use Appearance &c: Lect Lecture 6th. Of the Nerves. The Nerves are now by every body allowed to be a system of the vessels, and they are a fasciculi of white fine fibres, arising from the Medulla Oblongata & Spinalis, egressing in pain. Over the Brain are the Meninges, or, 1st. The Dura Mater which is externally, & a thick vascular substance within this & adhesive to the Brain is, 2d. The Pia Mater, which is a thinner membrane; between these two, some anatomists reckon another membrane, extremely fine & reticular which they call Tunica Arachnoides. The Brain is divided into three portions called, Cerebrum, Cerebellum, and Medulla Oblongata, the latter being being continued thro’ the spine of the back is called Medulla Spinalis. The Brain is supposed to be vascular, & its substance of two cortex; external of an Ash color is called Corticalis; internal of a white color called Medullaris. The Nerves are of the same substance with the Brain, and are properly aportion thereof continued to all the parts of the body. The Nerves as they arise in pairs soon after decussate, or change sides as in the Optic Nerves, the left going to the right Eye, & the right to the left; hence a wound, on one side of the head affects the contrary of the body. The Nerves are distributed thro' the body in much the same manner as the Arteries; the one proceeding from the Brain the other from the Heart, but with this difference & difference, that the trunks of the Arteries grow less the more they are ramified together with the ramifications ad infinitum; but the capacity of a constituent Nerve never decreases they being imperceptible, but the number of the likes of the Fascicule decreases in proportion as the bundle ramifies, thus the cords of the Nerves wc. as they egress from the Brain contain an innumerable number of constituent Nerves, decrease in No. but not in capacity ad infinitum in proportion as they are ramified. The Nerves anastomose, but not in the same manner as the blood vessels do, by uniting their tubes but only by their coming in contact with each other; these anastomoses are called Plexuses. sometimes little knots appear in Nerves called Ganglions, some imagine these knots proceed from pressure & inflammation, but this cannot be as they are found found in the Viscera, & in a Foetus where no pressure could happen. Lancesi, reckons the use of these Ganglions is for an an additament to the Brain; because he says more nerves go from them than go to them, but from the substance of these knots not being the same wth. the brain, that cannot be. others think they serve to stop the nervous fluid from flying out at the end of the Tube without the impulse of the will by means of muscular fibres, they being only in those nerves destined for voluntary motion; this also appears to be false. The termination of the nerves is but little known, but supposed to be in every part of the body. The use of the Nerves is for sensation, motion, nutrition, &c: the Brain being called the sensorium Comune to wc. the Nerves carry all the sense communicated to them Voluntary Voluntary motion is acquired by experience, as is evident from a child whose will is frequently contrary to the Act performed. Of the cellular Membrane. The cellular membrane is of two kinds, the one adipose containing fat, the other reticular without fat; it is a net like substance, vascular, very thin and tender, consisting of many cells & its fibres very fine: the cellular membrane is continued throughout all the body, except some of the viscera & is called by some the membrana Musculorum Comunis. The cells of the reticular part of the cellular membrane communicate with each other, as is evident from an Anasarca which is a transudation of Phlegm into the cells, & so from the one to the other, as is evident from the Legs swelling by walking & subsiding when lying down x See the Londn: med: observations vol: 2 down; hence Eccymosis from a false Aneurism, Diaeresis, Contusion &c: by which the blood insinuates itself into the cellular membrane; hence also the great quantity of water evacuated from a scarification in an Anasarca. An Emphysema is a remarkable proof of the communication of these cells; this is caused by the air distending these cells & often happens from a fractured rib puncturing the Lungs by w.c the Air gets into this membrane; a remarkable instance of this happened in London, by w.c the patient swelled to that degree that his eyes could not be seen; Dr. Hunter x made a puncture at the Eye by w.c the air gushed out, & by puncturing & rubbing he was cured. Putrefaction will cause an Emphysema, from the fermentation generating air; hence hence a drowned person will after a while rise to the surface of the water. The fat contained in the adipose cells differs in different bodies; in a Foetus the fat is soft, and gelatinous; in children of a year or two old, the fat is chiefly next to skin; hence the fatness observed in children; & in adults the fat is solid and mostly internal. The cellular membrane serves for easy smooth motion, for a defence to the body, to keep the parts warm & preserve the figure of the body, & blunt acrimony. some animals we reckoned to be nourished in the Winter by their fat. Lecture 7th Of the Bones. Here we shall, 1st. describe the external conformation of the Bones, 2d. examine their internal structure, 3d. their connection, & 4th. Explain their use. A Bone is a hard fibrous compact substance. various Bones have various shapes & conformations, some are cylindrical & long, others flat, & broad, irregular &c: bones are said to be made up of Fibres forming Lamellae, fastened together by means of oblique or transverse fibres. Bones have processes and Cavities. Processes have different names from their different forms, & appearance: thus, a Condyle is an oblong process arising from the extremity of a bone; a Corone is an oblong process process terminating in a point; Spine is the sharp ridge of a Bone; Supercilia is a brim round a cavity; a protuberance is a rough process of a bone. Processes are of two kinds viz Apophysis, & Epiphysis; Apophysis is a process growing out from the body of a bone. Epiphysis is a process growing to the body of the bone, being originally separate therefrom by a different Ossification. The cavities in bones are of two kinds, one for Articulation, & the other for the lodgment of soft parts; cavities for Articulation are of three kinds, 1st. Round & deep called Catyloid, 2d. round but superficial called Glenoid, and 3d, deep & narrow called Alveoli, the Articulation of Bones is by Galen called [illegible] Joint & by him is reckoned of 2 kinds, 1st. With motion called called Diarthrosis. 2d, without motion called Synarthrosis; each of these are of 3 kinds. Diarthrosis, are. 1st: Enarthrosis, 2d: Arthrodia, 3d: Ginglymus. Synarthrosis are, 1st: Suture or Raphe, 2d: Harmonia, 3d: Gomphosis. The connection of bones is termed their Symphysis, & is of two kinds: the one wth. and the other without an intervening substance: the first is that of the Cranium by mutual Indentation. the second are of 3 kinds viz: Synchondrosis, Syneurosis & Sysarcosis. Periosteum is an elastic fine membrane, that covers the bones except at the joints teeth &c: its case is for the insertion of vessels, to strengthen the Epiphysis &c: the cylindric bones are all hollow, & so are most others & contain Marrow, the ends of the bones are cellular. F Lect. x see Edinburgh med: Essays. Lecture 8th Osteogonea. In a Foetus, the first months, there are no bones, nothing but a gelatinous fluid; then it gradually grows cartilaginous, & in time becomes boney; some imagine Bones are formed of Cartilages only by an expulsion of the redundant fluids; but Dr. Nisbet x says, & it is now general recd., that in Ossification, there is in the blood, or a fluid secreted therefrom, an ossifying juice; consisting of particles wc. are not apparent; that wherever nature designs an ossification between membranes, or a cartilage she occasions a more than ordinary afflux of fluid which distends so much the vessels wc. were before invisible as to make them capable of receiving the red globules of blood wc. is always to to be seen near to where ossification is begun. In this blood gritty particles are to be felt by the point of a knife, which have been formed by the attraction & cohesion of the particles of the ossifying juice obstructed along with the other grosser fluids in the beginning of the vessels, prepared to receive the influent juices. The membranes or cartilages some as alied between wc. or within wc. the bony particles are deposited or shoot; but without any any intermixture of the particles of the bone & cartilage, or continuation of the fibres of one substance to those of the other as is evident in bones made perfectly clean, the cartilage dropping from it as easy or easier than an acorn from its cup, & there is a smoothness of the parts of both cartilage and and Bone which show that there is no conjunction or union of the fibres of the two substances. While bones are increasing within Cartilages, the cartilages are extended & spread out, by wc., with the pressure they suffer & the great influx of various fluids, & the nutritious matter being kindred to flow freely into them, they decrease continually & at last may truly be void to be entirely destroyed. Bones digested in Acids for sometime grow flexible & gelatinous like a tendon, by which it appears the great quantity of Earth they contain makes them hard rigid. Bones are furnished with Arteries and Veins, as is evident from the drops of blood blood seen in sawing bones lengthwise, & upon their appearing tinged of a red color after the animal has eaten Madder. Dr. Havers divides the blood vessels into sanguiferous, & medullan the latter enter the bones mostly near their center in an oblique manner. Bones have Nerves as is evident from their exquisite sensibility where amputated, or exfoliated, & granules of flesh have sprouted out. Diseases of bones are 1st: a softness & rickety disposition. appearing generally from [illegible] to the 3d. year after birth, though the habit may continue thro' life. It seems to be owing to an Idiosyncrasy or a want of bony matter in the constitution. Sometimes it is said to arise from the pox & scurvy, but probably less frequent than from the other cause. We have the history of a species of Scurvy in France that affected the Bones & separated the Epiphysis. In Anson’s voyage we are told the Callus of bones wch. had been fractured & united again for may years were disposed by this Scurvy ~ Softness from a venereal Taint can be nothing more than a Caries of the bone. the disease first affecting the Periosteum & then communicating itself to ye. subject bone. As to softness from Idiosyncracy as its called; or from a particular state of the solids & fluids. Mr. Goodye furnishes us with a history of a woman whose bones without any apparent cause grew soft; her body shortened, & at last she died, & he found that he could easily cut through the limp bone & all. The academy of Paris give a more remarkable history of a woman whose bones were so soft that at length they had not solidity enough to gird the muscles action—no kind of a scorbutic or pocky taint could be observed. see Vanss 4h:423. Mr. Gooch had a case of this kind under his care, when the patient died he found the bones so soft that he split the thigh bone, the Tibia & bones of the foot the whole length very easily with his knife. Dr. Tilton of Dover relates the like Bones may likewise loose of their bulk like other parts from a loss of juices as in alveolar & vessels of old people. 2dly: Fractures. All bones have a tendency to unite again after being disjoined w:ch is effected by means of a Callus this was formerly supposed to be unorganized, but is now known to be vascular by injections & being tinged with madder. When a Callus is broke it will unite again only to the opinion of some authors. A pupil of Dr. Haller’s in a Thesis he wrote on the subject say that the Callus is first a bloody matter, then slimy, next gelatinous & then vessels from the bone & meditullium shoot out thro' it & ossifications begin directing themselves quaquavenum & thus the Callus Lecture 9th Of the Cartilages & Ligaments. Cartilages are compact, opaque, & a little elastic: of wc. there are 3 kinds, 1st: such as supply the place of bones as the Nose, Trachea Artena &c: these preserve the structure of the part & admit of motion. 2d. such as supply the place of bones before they are formed as in a Foetus. 3d. such as serve for the Articulation of bones. Cartilages differ from bones in not having Fibres nor blood vessels to be siphoned, tho’. they are imagined to be vascular; they serve at the Articulation by their smoothness to prevent abrasion; they won’t granulate nor exfoliate but may be corroded. Ligaments is compleat. sometimes the bones won’t unite but with great difficulty. 3dly: Caries. A caries in alone is similar to an ulcer in the flesh it has circulation but it is unsound & often shoots out irregularly as the fungus of an ulcer See more so in med:[illegible] 2:h:k0 [illegible] [4?377]. 4thly: Spina ventosa – this is a caries beginning on the inside of the bone & affecting it clear thro', hence Surgeons bow into the bone to let out the matter, but in general the limb is to be taken off. See Van Swieten 4 p 377 A node by some is said to be an Exostosis of the bone, but for the most part if not always it begins in the Periosteum. should be open'd before it affects the bone 5ly: Anchylosis is a stiff joint having little or no motion. from the bones running into each other & the cartilages being eroded. Van swieten vol 4 p 457 gives several curious cases of Anchylosis of all the joints in the Body. See also Le Bran’s Surgery. x where it covers the Cartilage. it is calld. Perichondrium the external lamina of the capsular ligament goes from the substance of one bone to the other over the articulation & is inserted beyond the Epiphysis &: Friction 6th. Exostosis is a tumefaction of a Bone or an excrescence growing out of the bone. It may proceed from a redundancy of ossifying particles in the system or in the part only from a morbid cause see Van swieten 4 p 424. See the case of 9: Scott of the Pennsylvania Hospital in my Adversar: med: See Cheselden p 5. Ligaments are firm, compact, unelastic, membranes; serving to connect the joints, prevent luxation &c: The Ligament, Bones, Cartilages, Tendons & Dura Mater are now reckoned none of them to have much sensibility in a natural state. v: Whytt & Haller The capsular ligaments are very strong & compact, & made up of hard Lamella, the inner lamella being a reflected membrane going over the head of the joint. cover the Cartilage x & so coming to join the external lamella, which is firmly inserted near the joint. These capsular ligaments forming a sac in wc. is contained, a mucilaginous liquor serving to lubricate the joint: for for in all Joints; for motion there are synovial glands which discharge the above synovia, this is subject to be disordered: 1st. to become thin & Icorous, 2d thick and inspissated &c: It is generally received of late, that the capsular ligament is lacerated in a Luxation of a joint unless from internal cause, or a relaxation; & violent extension is unnecessary in reduction of the same; no more being necessary than to bring the ends even, and then coax them into their proper places, & there keep them by proper dressings & bandage. For as particular description of the Bones vide Monro’s Osteology, and of the muscles Douglas’s Myographia Lect. 40th: In the Osteology we divided the body into three parts, viz: Head, Trunk, and Extremities; the Trunk of the Skeleton we subdivided into, the spine, Thorax, and Pelvis, but in a fresh subject we divide the Trunk differently, viz: into The Thorax, and Abdomen, or upper, & lower belly. The Viscera of the Thorax are only the Heart, and Lungs, & therefore not necessary to be subdivided. The Abdomen is separated from the Thorax by the Diaphragm. The Abdomen by reason of its largeness and the many Viscera contained therein, has been divided into several parts, by imaginary lines, for the readier knowing the particular situation of each Viscus. The divisions are as follows, 1st G 1st. That which lies under the Cartilage Xyphoides, is called Scrobiculus Cordis, 2d. From the Scrobiculus Cordis down to within 2 or 3 inches of the Umbilicus is called Regio Epigastrium, circumscribed, and on each side there of it is called Regio Hypochondrium. 3d. From the Regio Epigastrium to 2 or 3 fingers below the Umbilicus is called Regio Umbilicus, circumscribed, and each side Regio Lumborum, 4th. From the Umbilical Region to the Os Pubis is called Regio Hypogastrium, and on each side the Regio Hiaea 5th. The lowest part is called the Regio Pubis. As we are sometimes called to open the body of a deceased person before their friends, particularly if they died of a violent death; we should endeavor to to do it with regularity & decency. The antients opened the Abdomen by beginning at the Sternum & directing the knife along the False Ribs to the Loins, then along the spine of the Ilium to the Os Pubis; and laying the loose part over on the contrary side. Others begin at the Xephoid Cartilage & make a straight incision down to the Umbilicus, then dividing the incision directing one to the spine of the right, & the other to the spine of the left Ilium, and turning each part back. But the best method is to begin the incision at the Xephoid Cartilage and going straight down to the Olsa Pubis and then another transverse from the Navel to the Loins each way. The Thorax is opened by pushing off the Teguments & Cutting the Cartilages by the Sternum. Lect. All the internal superficies of the cavity of the Thorax, the ribs, cartilages of the ribs & convex side of the Diaphragm except where the pericardium lies in contact wth. it are lined with one continued, thin, nervous, very strong membrane, internally very smooth called Pleura. On the external superficies of this every where is the cellular membrane wc. in very fat animals is often so enlarged with fat as to lessen the capacity of the Thorax & these cause a shortness of breath. The Pleura when it gets round to the vertebra elevates itself perpendicularly lowd. frenum wc. with the one on the other side from a doable pleura called Mediastinum dorsale. The same duplication is made of the Sternum when it is called mediastinum pectorale. The pleura likewise covers all the muscular circumference of the diaphragm above the cellular membrane wc. arising up together with the orb of the septum from the back sternum, from the external membrane of the pericardium wc. is the third cavity of the Thorax in the middle between the 2 cavities of the pleura containing the Lungs & formed a conjunction of them This membrane of the pericardium is lined internally with a thin membrane wc. is a branch of the external membrane of the Heart. The great vessels from the Heart as they pass thro' the pericardium & go on beyond it or move also at above the cellular one from the external membrane of the pericardium. this membrane forming about to the pulmonary arteries & using wc. when they arise at the Lungs is expanded out & forms the extenal coat of the Lungs. Kaan de Perspi Hippocrat. Lect. 41st: Of the Pleura. The Pleura is a fine membrane, which lines all the cavity of the Thorax and is reflected back over the Lungs. There are two Pleura one on each side, like two bladders beginning as we may suppose at the sternum and going round within the Ribs to the Vertebra of the Back, then reflected back upon the outside of the Lung (making the coat of the Lungs) to the sternum; there running in or uniting with the first Fibres of the same and so on the other side; where the two Pleura meet at the sternum; they are not quite in contact with each other, but there is a small space left between which is filled up with cellular Membrane. Of Constat pulmo duplici vasorum genere, aerifero scilict & sanguifero. Aerifera omnia vasa ortum ducunt ex una trachea, quo mox a faucibus intitium capiens, ante oesophagum, descendit, thoracem post thymum intiat; post cavem descendentem & pericardii apicem, as quartam thoracis vertebram, qua est a superiore una tertia pars ipsius pulmonum longitusinis divaricatur. Hujus dein crura tendunt ad utrumque pulmonem, & statim dividuntur, in homine dextrum in tres, sinistrum in binos ramos, qui tune bronchia dicuntur, as totidem pulmonum lobos, quos ubi ingressa funt, disperguntur statim in ramos minores, & minores; qui omnes ad obtusum angulum, respectutrancorum, oviuntur. Remi autum majors ingressi pulmones, pro maxime parte, descendunt, pauci recti procedunt, ubi ingrediuntur; aliivero adscendunt aeriferorum truncorum, & horum ingressum est. quod prater Eustachium meminen observasse video. Ultimi Of the Lungs. The Lungs are Vascular Substances composed chiefly of Air Vessels, and Blood Vessels; the Air Vessels are Ramifications of the Trachea Arteria, and are called Bronchia; the blood Vessels are ramifications of the Vena and Arteria Pulmonalis; beside-which they have an Artery wc. serves to nourish them, called the Bronchial Artery coming from the Ascending Aorta together with Nerves and Lymphatics, and some say also Parenchyma which is perhaps no more than cellular Membrane. Some Anatomists suppose there are little follicles or cells at the extremity of the small Bronchial Vessels, which if there is are not discernable. Ultimi autem ramuli ommitunt cartilagineam indolem, & expanduntur in vesiculas oblongas, membranaceas, cavas, qua Malpighiana dicuntur, ox quibus fiunt area, & lobuli, qui tandem pulmonum lobos efficiunt. Comitantur aerifera hac vasa, in omni decurser, ad vesiculas usque, vasa Sanguifera, qua omnia oriuntur ex arteria pulmonali, qua cordis dextro ventriculs egressa, qua parte superiore ventriculs sinistro jungitur, adscendit, mox se incurrat, arcum facit, & sub aorta decumit. Descendit The inside of the Trachea arteria is lined with a membrane in which are small glands that secrete mucus for lubricating the its internal surfaces; in cold, this means is sucked into great quantity—sometimes inspissated is spit up very thick especially in the morning. Dissection has taught us that this membrane is the seat of that disease in children called the Hives & is found separated from the cartilages – nothing proves so useful in this disease as large doses of 8. I have known 10 g of calom: given to a child 2 years old produced 2 copious stools & disease immediately vanished The Lungs are divided into two Lobes, by means of the Mediastinum and Heart. The right Lobe is divided into three Lobuli by fissures; and the left Lobe is divided into two Lobuli. In a natural state, the Lungs are every were in contact with the Ribs, so that there is no vacuity left. The Trachea Arteria is composed of cartilaginous Rings, which behind are not quite shut but a small membrane between; each of the cartilages are connected likewise by membranes. The Lungs are liable to inflammation, and Ulceration. In inflammation of the Lungs we should use plentiful bleeding, oiluants, fomentations externally and the steams of warm liquors particularly Vinegar, into the Lungs thro' the mouth. x The ventricles are divided by a middle partition called Septum Cordis. Lect. 42d: Of the Hearts. The Heart is a strong muscular substance, situated obliquely to the left side, more than the right; part of the inferior and or Apex in contact with the Diaphragm, and pointing between the sixth and seventh Ribs on the left side; the Apex being likewise nigher the sternum than the Basis. The Heart is the Origin of the Veins and Arteries. There are four cavities in the Heart, two Auricles, and two Ventricles; x one right and one left, at the right Auricle the Vena Cava enters, and at the left: the Vena Pulmonalis; at the right Ventricle the Arteria Pulmonalis egresses, and the Aorta from the left. M x these cordae Tendineae arise from the Carnae Columnae. At the entrance of the Vena Cava into the right Auricle of the Heart are three Valves called Valvula nobilis, and about the middle of the Auricle there is a little knob called Carna Sesamoidea: At the entrance out of the right Auricle into the right Ventricle and two valves called Valvulae bicuspides, connected by sou:e small tendinous cords called Cordae Tendineae x; the internal part of this Ventricle is rough & muscular having many muscular Pillars, called Carnae Columnae which serves for to strengthen the motion of the Heart and to work the blood so as to prevent its concretion & forming Polypuses,- which however sometimes happens. After the blood has passed out of the right Ventricle into the pulmonary Artery it is prevented from returning by three valves Valves named Valvulae Semilunares. There are likewise Valves at the entrance between the left Auricle and Ventricle named Valvulae Mitrales fastened by the final Cordae Tendineaes on the left side of the Heart. The left Ventricle is larger and a stronger & much thicker muscular bag than the right Ventricle, its internal part tougher and the Carnae Columnae bigger. As the entrance out of the left Ventricle into the Aorta are likewise three Semilunar Valves. The Heart is contained in a strong Membranous bag called Pericardium the internal part of which bag is very smooth and lubricated with a juice that continually transudes through the same H. Same Dr. Plott in his History of Staffordshire attests of his own knowledge the case of one Mary Eagle who drew two quarts of milk from her breasts every day besides what her child sucked and that she could make two pounds of butter every week ever since she was brought to bed which was above five months when the Dr. saw her. Borellus in his Hist: & Absence: physioc-med: related an instance of the like native in one Mary Caron a Taylor’s wife of Bologna who afforded milk enough for two children & made Butter besides Biog Dictionary Led: Esq: Lect. 43d: Of the Diaphragm The Diaphragm is a large Muscle between the Thorax and Abdomen, the muscular fibres of which arise from the internal part of all the ribs below the sternum, and from the lower end of the sternum, these fibres terminate in a tendinous expansion which is nearly in the middle of the Diaphragm, and which is of an oblong figure coming very nigh the sternum upon which part the Apex of the Heart lies, and from thence turning down towards the Angle of the Ribs and is called the oval tendon of the Diaphragm the lower part of the Diaphragm is likewise muscular and on each side of the Vertebra are muscular Fibres sent Sent down some distance called the Crura of the Diaphragm, these terminate near the Origin of the Psoas muscles which arise at the internal part of the Vertebra of the Loins and pass out of the Abdomen at the Inguen to be inserted into the Os Femoris. it is by making way through these muscles that Abscesses of the Loins sometimes fall down to the Thigh and are opened and discharge their contents there. There a three Apertures thro' the Diaphragm, one of the right side of the Vertebra through which the Vena Cava goes, a second contiguous to the Vertebra inclining a little to the left thro' wc. goes the Aorta, a third over the Aorta & exactly over the Vertebrae through wc. the Oesophagus goes. Of Lecture 44th: Of Respiration Respiration is an alternate dilatation and contraction of the Thorax the former performed by Inspiration and the latter by Expiration. The parts subservient to Respiration are divided into Active and Passive The active parts are the Ribs, Sternum, Heart &c: acting upon the the passive which are the Lungs themselves. The dilatation of the Thorax happens both in length and diameter; in length by means of the Lungs pressing upon the Diaphragm and thereby rendering its convexity more plane, the diameter is increased by the motion of the intercostal muscles &c: Thus the capacity Capacity of the Thorax is increased and as there is no vacuum between the Lungs and ribs allowed of in a natural state, the capacity of the Lungs will also be increased and there will be a vacuity in the Lungs wc. nature not admitting of and by the pressure of the Atmosphere rushing through the Aspera Arteria they are soon filled with Air making Inspiration. The fresh Air that is drawn in by Inspiration stretching the Bronchiae and stimulating the same cause them to contract and expel the Air making Expiration, some Authors imagine these are small Muscles between Between the cartilaginous Rings of the Bronchiae which they call Musculi Mesenchrondroeci serving to contract the the same in Expiration. The uses of Respiration are four, 1st For the circulation of the Blood, thus in Inspiration the Lungs are distended and the fine contorsions of the Arteries are are elongated so as to allow, blood to pass through them whereas in a collapsed state the blood cannot pass through them. in Expiration the Lungs collapsing push the Blood through the Veins into the left Auricle of the Heart. 2d. For sanguification by communicating the Blood making it more florid & denser 3. For cooling the blood 4th. For Vocification, exclusion of [illegible] &c: Of the Peritoneum This membrane is similar to the pleura, being smooth on one side & connected by cellular membrane on the other; it is reflected from the contained path to the containing. It makes a compleat bag 1st: covering the viscera by intimate connection, & then covering the abdominal muscles loosely on the inside. The peritoneum has been considered as a double membrane true or false, the last is no more than cellular membrane wch. connects the peritoneum to the external parts. We may conceive that all the viscera are behind or without the peritoneum, wch. running up on one side of a viscus is reflected back on another so as to form an almost compleat cover to each viscus separately, so that by a very nice dissection the peritoneum may be taken out in a compleat bladder having no perforation at all, leaving all the viscera undisturbed. Lecture 45th: Of the Stomach The stomach is a large muscular bag situate Obliquely from the Left Hypochondrium to the Epigastrium and serves for the reception of our food & digestion of the same, it has an upper & lower curvature called the lesser and greater curvatures of the stomach. There are two Orifices to the stomach; the superior one called the Cardia which enters it from the Oesophagus don't open at the fundus of the same but obliquely, at the side an inch or more from the end. Towards the inferior end the stomach grows smaller & turns up opening into the Duodenum by an Orifice called the Pylorus where there is J The Nerves of the stomach come from the par vagum. Is a partial kind of a valve which does not prevent the regurgitation of fluids into the stomach being only a thickness of the internal coat of the stomach. The stomach is furnished with Nerves and blood vessels. x Some Anatomists say there are small glands in the stomach, but if so they are not easily discovered, there is however a fluid discharged into the stomach from the extremities of the Arteries called the Gastric lymph from the gastros the Greek name for the stomach, there is likewise Lymphatics which absorb the redundant fluids & carrys it into the blood. The coats of the Stomach are three 1st. coming from the peritoneum and is called called the Peritoneal Coat. 2d. Muscular being composed of thin muscular fibres running longitudinal and transversely by which the capacity of the stomach is decreased the readier, to expel its contents. & 3d: Villous or internal Coat which is thin. Of the Intestines The first Intestine next the stomach is the Duodenum beginning at the Pylorus and ascending two or three Inches, has then two or three inflections pulsing down & across the Vertebrae — being all the way tied fast by a duplicature of the Peritoneum to the back, having no mesentery. The Ductus Choledocus & ductus Pancreaticus both enter the Duodenum several Several inches from the Pylorus, not both by one Orifice but by two very near together, next the Duodenum is the Jejunum, & then the Ilium which is the last of the small instestines. The coats of the Intestines are three the same as the Stomach, and in the small intestines are anular duplicatures of the internal Villous coat forming what is called Valvulae Coniventes which serve for two purposes, first to make the passage rough & prevent the Faeces, from passing on too fast and secondly to give more capacious origin. to the Lacteals The Ilium enters the Caecum not at the end but about an Inch there from obliquely the blind end only being Being called Caecum, where there is an appendage called Apendicula Vermiformis. At the entrance of the Ilium into the great Intestines, there is a Valve formed by the inner coat of the Colon & called Valvula Colli which in a sound state entirely prevents the regurgitation of the Faeces or any fluids passing, injected per Anum. The Colon runs up the right side then along under the stomach and down the left side, surrounding all the Abdomen, hence Clysters beside discharging the Faeces serve the purpose of a fomentation to the contents of the Abdomen. The Intestines are furnished with blood vessels from the two mesenteries except except the Rectum which receives its from the Hemorrhoidals. The Mesentery is a double membrane formed by a duplicature of the Peritoneum serving to connect the Intestines. & through which which the blood vessels go to be distributed to the Intestines, through it likewise goes the Lacteals which are fine Lymphatic or absorbent vessels arising from the villous coat of the Intestines and passing through the mesentery, they terminate in the Receptaculum Chyli, to be described hereafter, there is also a great number of Glands in the Mesentery through which the Chyle passes, and by which it is supposed to receive some alteration. These glands are very small. Lect. 46th Of the Lacteals & Thoracic Duct The Lacteals are an innumerable number of small vessels arising as before said from the villous coat of the Intestines & running through the mesentery in the duplicature of the same and through many fine glands and terminate in the Thoracic Duct serving to convey the Chyle The Thoracic Duct is a small canal running up the Vertebra of the Spine between the Aorta & Vena Azygos and under the Vena Cava until it gets above the Heart then it turns a little to the left and ascending empties itself in to the subclavian Vein. The lowest end of this Duct has been called Receptaculum Chyli but improperly as its no larger than the rest of the Duct neither do all the Lacteals enter there, but some higher Of Digestion Digestion is that change of the Aliments whereby they are filled for the nourishments of the body, this is different from the different juices mixed therewith and in the different parts of the body. The first change that happens to the Aliments is in the mouth by means of Mastication and mixing with the Saliva by which it is somewhat dissolved and fitted for more easy Deglutition Saliva is a clear mucous transparent fluid secreted by the Glands of the Mouth in the great plenty, and is of great use in digestion. After the Aliments is sufficiently masticated & mixed with the Saliva they are by the Tongue pressing against the roof of the Mouth forced into the Pharynx Pharynx and from thence through the Oesophagus into the Stomach. The Muscles employed in this act of deglutition are very many, serving chiefly to pull up the Oesophagus and to press the food down through the same, and we may very well conceive of the act of Deglutition by that of drawing a stocking on the Leg, part of the muscles drawing up the Oesophagus as we draw up a stocking upon the leg, and the rest pushing down its contents as we push down our leg into a stocking. The manner in which our food is digested in the stomach was by some of the Antients reckoned to proceed from heat K Heat, others reckoned it was performed by means of trituration, and others again from the different juices there mixed imagined it was performed by Fermentation, but modern Physiologists from many observations, think it is performed by all three jointly viz: Heat, friction and Fermentation. After the Aliments are sufficiently digested in the stomach, by the contraction thereof which is the beginning of the peristaltic motion of the Intestines, they are forced through the Pylorus into the Duodenum, where it continues some time and receives another change by having the Bile and pancreatic juices mixed therewith. The The Bile is an oily bitter, and attenuating substance endued also with a saponaceous virtue it will incorporate with Oils and when so mixed they are both soluble in water, it unites with salt forming a green color. by which it appears that the Bile is of great— use in attenuating the viscid part of the Aliments, and stimulating the— Intestines, the latter we are assured— of by this that Bile secreted and— discharged into the Intestines in too great a quantity causes a Diarrehea, and in a Jaundice where the Bile returns into the Blood and is not sent into the Intestines a Costiveness happens with while stools, and Boerhaave says Says the Gall of Animals is of use in this case to supply the want of Gall DeGraaf collected great quantities of the Pancreatic juice from Animals which he says is subacid it is reckoned to be somewhat of the nature of the Saliva, some reckoned it serves to sheath the Acrimony of the Bile but this in a natural state is not too Aerid These two fluids being mixed with the Aliments in the Duodenum the fluid and nutritious particles of the same are absorbed by the Lacteal vessels and by them carried into the Thoracic Duct to be conveyed into the Blood. These Lacteals are in all the intestines, but in the small ones in the Greatest Greatest plenty, That there are also Lacteals in the Colon seems evident 1st. From the rout the colon makes round the Abdomen, for if that is not for absorbing the particles that may chance to be not taken up by the vessels in the small Intestines why did it not go out strait like the Rectum and immediately terminate in Ans? 2. From persons being known to have lived a long time by Glysters, not being able to get any thing thro' the Oesophasgus, & it is known that they cannot pass by the Valve of the Colon. The contents of the Intestines are carried along by the Peristaltic motion thereof thereof. Vomiting is an inversion of the peristaltic motion and is performed by means of a deep inspiration which presses the Diaphragm against the stomach & a convulsive contraction of the stomach by which its contents are thrown up hence we learn that Emetics are good in Fluxes by inverting the peristaltic motion they stop the same. Of the Bile Bile is secreted in the Liver. It is 8 times as viscid as water. More subject to concrete than any other humour in the body. Its specific gravity to water is as 010 to 795. In a such quadrupeds & in the human species the bile is very bitter, but most so in carnivorous animals. Recent bile easily mixess with water. It mixes with oil by triture. Mixed with water it partakes of the property of Soap, dissolves oil so that it will mix with water & takes out grease spots. It dissolves resins & mixes with balsams. It dissolves Myrrh Bdellium & Wax like the yolk of an Egg, & is supposed to dissolve the Blood when mixed with it as in a Jaundice. The Ductus Choledochus may may be compressed & stopped by the Duodenum being distended with flatus. Eating Mushrooms has been known to distend the duodenum greatly & trangulate the ductus choledocus as it were with a ligature. It may also be obstructed by the contractions of the fibres of the intestine from stimuli as happens in the Colica pictonum, biliosa, inflammation of the duodenum, acrid purges, glass of Antimony & poisons. Hither we may refer the Jaundice in Infants which is removed by Rhubarb. Storck has seen the ductus choledochus obstructed with a cheesy coagulum. Hillary says this is frequent in the warm Islands. See Monro Ed: Ess: v. p 247 Baglivi prax: med: Haller tom: 6. p 590 x about 4 fingers breadth below the pylorus. Lect. 47th Of the Liver The Liver is a large Viscus situated immediately under the diaphragm mostly in the right Hypochondrium extending over the Stomach into the Epigastrium it is convex above and concave below suspended by three Ligaments one above to the Diaphragm one broad on the upper part of the round ligament from the Umbilicus which was the Umbilical Vessel in a foetus state. There are several fissures in the Liver 1st. Divide the great lobe from the lesser one. 2d. divides the Lobulee spigeli & the third where the Hepatic Vessels enter; The Vesica Fellis lies in a depness in between the two lobes of the Liver from where goes a duct remarkably contorted to appearance about two inches when it joins the hepatic duct, both of them united form the Ductus comunis Cholidochus which terminates in the Duodenum. x The Coat of the Liver comes from the L x sometimes called Tunica Glissoniana *The hepatic Artery divides a little before it enters the Liver one branch going to one lobe & the other to the other Lobe; it serves to nourish the liver & is said to secrete a small part of the Bile, some few of its evanescent frame has terminating in the pori biliarii as is proved by injections. The Peritoneum x beside which some Authors describe another coat wc. is scarce to be seen, The Gall Bladder has three coats 1st. from the Peritoneum, 2d: Muscular & The 3d. Villous, appearing like a honey comb inside. The Liver is furnished with Veins Arteries & Nerves. The Blood Vessels are the Hepatic * Artery & Veins & the Vena Porta. The Vena Porta is like an Artery first in its Office & 2dly. in the thickness of its coats; it arises from all the Viscera of the Abdomen terminating in the Liver and is supposed to carry the blood for the secretion of the bile, 1st. From the longness thereof & the smallness of the hepatic Artery. 2dly: By injections passing from it into the biliary Duets &c: It is certain however that the blood being carried into the Liver, part of it is converted x The general opinion of the ancient Anatomists was that the bile was conveyed into the Gall Bladder by little ducts running from the liver immediately into the bladder which they called ducti hepaticistics. Pechlin was the first who denied the existence of these ducts in the human body, then Ruysch, Cowper, Bidlow, Berger, Morgagni, Heister, Ludwig, Carsons, Lieutaud, Ceyer, & Cheselden. who says if a ligature be applied round the cystic duct, or if it be obstructed the gall bladder does not become turgid. Bohnius emptied the gall bladder of bile then tied a ligature round the cystic duct & upon examining the same several days afterwards found no bile in the cyst itself but the part of the duct between the ligature & liver was greatly distended. Bianchus & Haller have done the same. This clearly proves that there is no communication between the Liver & Gall bladder but by the cystic duct. What was supposed to be Hepatocystic ducts is demonstrated to be only blood vessels by Ruysch, Guntz, Haller Morgagni & others. converted into Bile & carried by the pori Biliarii which all meeting together form the hepatic duct though the hepatic duct to the cystic then regurgitates into the Gall Bladder; that the Bile regurgitates thus x into the reservoir is proved 1st. by there being no other passage though some supposed there was by little ducts wc. they called cysto hepatic ducts, but there is no such is evident from the injections not passing through that way into the Cyst, & in a Viper the Gall Bladder is vitiate some distance from the Liver. Horses & Deer have no Gall Bladder. That the Bile goes through the hepatic Cystic Ducts into the Gall Bladder is proved 2dly: by blowing into the hepatic duct the wind passes free into the cystic than through the ductus cholodochus. The remainder of the Blood is received by the Veins & carried back to the Heart Diseases x more frequently if not always the Jaundice arises from an obstruction of the Ductus communis Cholidocus An obstruction of the cystic duct alone will not occasion a Jaundice. Diseases of the Liver are: 1st. Hydatides these are of two sorts the first tumors composed of several lesser cysts filled with a gelatinous matter, the other a kind of vascular Cysts, the fluid circulating through it. 2d. Inflammation this is best relieved by plentiful bleeding warm relaxing and stimulating applications &c: It sometimes suppurates & even grows cancerous. 3d Scirrhi like other Glandular parts 4th. It gives origin to the Jaundice wc. proceeds from an obstruction in the Cystic x duct by wc. means the Bile is prevented from going into the Gall bladder and therefore returns into the Liver where it is absorbed by the Veins or lymphatic Vessels & carried into the blood & by that means tinges the shin, the cystic duct may be stopped by concretions tumors compressing the The same or more commonly by means of a stone lodged therein: a stone or concretion is best removed by Vomits which agitating the parts serves to remove it or by friction stimulating the same. Some have imagined that a Jaundice proceeds from a scirrhus Liver, but this is proved to not be the cause as no Jaundice can be unless the bile is absorbed after it is perfectly made Transient Jaundices sometimes happens to Children from a spasm of the Duodenum from acidities or otherwise hinders the Bile from passing therein & which is relieved as soon as the spasm is removed. Durable Jaundices happen when the Obstruction of the Cistic duct cannot be removed Lect. 40th: Pancreas is a long slender conglomerate Gland situate obliquely under the stomach between the spleen & Duodenum. each little x Haller supposes the pancreas secretes three times as much fluid as the salival Glands. * a costiveness and a pain in the region where this gland is seated is the common symptoms of its being obstructed. little acini or knot supposed to be the extremity of an Artery wound up in a knot and the whole vascular like the liver and all the other Glands of the body. from each acini goes a small excretion Duct which terminates in a larger duct in the middle of the Pancreas & called the pancreatic Duct & through which the pancreatic juice flows into the duodenum, the glands of the pancreas being the same with those that discharge the Saliva are supposed to secrete the same juice and for the same Use. x Diseases of the Pancreas are Inflammation, Cancer, & Schirri, which * are very difficult to be known until past cure they are however removed much in the same same manner as the same Diseases on other parts, Soap is a very good thing in this case which not only seen x This appears very reasonable though it was never taken notice of by any author before Mr. Monro. Is a good resolvent but supplies the place of this juice in digestion. Sometimes a Diarrhea happens in a Salivation and proceeds from a too great a secretion of the pancreatic juice which being the same with that of the saliva is supposed to be effected in the same manner with Mercury & is only to be removed by removing the cause. x Omentum is a fatty double membrane composed or formed by a duplicature of of the Peritoneum it has an appendage between the Liver & stomach called the Omentum minor & may be inflated. Uses of the Omentum are to lubricate & keep the Intestines warm, and it is supposed to supply oily particles to the Bile and also the blood. It is sometimes much distended with Fat and in very lean subjects quite reticular. Spleen Of the Spleen The Spleen is a roundish lobulated Gland situated in the left Hypochondrium it is furnished with blood Vessels and but very few Nerves. The Antients supposed its use was to counterbalance the Liver, others thought it contained a fluid called the Atrabilis, but the moderns mostly think that it is subservient to the Liver, it has been taken out of several animals without any apparent damage and is not therefore a vital viscera. It is subject to very few diseases, scarce ever being inflamed schirrius or cancerated, by reason of the fewness of the nerves, its only subject to a viscidity of its fluid and an enlargement therefrom. Lect. x The arteries generally divide into three branches and the vein into two before they enter the Kidneys. Lect. 49th Of the Kidneys The Kidneys are two Glandular bodies situate between the false ribs & Ilium. the situation of the right Kidney is somewhat lower than that of the left oweing to the Liver being on that side. The blood vessels of the Kidneys are an Artery and a Vein called Renales or Emulgents the right emulgent Artery is longer than the left & the left Vein than the right. These vessels enter at the Pelvis and are distributed through the same. x The external part of the Kidney is called Cortical the thickness of which is irregular and in this the Urine is secreted and emptied into little ducts in the inner part M x the pelvis is an enlargement or expansion of the of the upper part of the ureter where it enters the Kidney or rather where the united urinary Tubes regress out of it. part of the same, which is called the Mamillary part of the Kidneys. The little ducts into which the Urine is secreted are called Tubuli Urinarii and are in number about a dozen, these all unite in the Pelvis x forming the Ureter which is a membranous canal conveying the Urine from the Kidneys to the Vesica Urinaria. The Ureter as it enters the Pelvis of the Kidney divides into three parts one going towards each end and the other through the middle. The coats of the Kidneys are two, the first called Adipose and the second Membranaceous. There is an appendage to the Kidney called Glandula Renales or Gland Glandula Succentriari situate at the top of the Kidneys its particular use not known but supposed to be subservient to the Kidneys. Diseases of the Kidneys are, Inflammation, Diabetes from a too great laxness of the Vessels allowing the red particles of the blood to pass through them, gravel, Scirrhi &c: Lect. 50th: Of the Bladder The Bladder is a membraneous Bag situate in the Pelvis the upper part of which is covered with the Peritoneum but when it is very much distended it protrudes about an Inch above the Pelvis & being there covered with the Peritoneum Peritoneum & in this place is the upper Operation for the Stone performed by making an Incision into the Bladder without cutting the peritoneum the doing which would be of dangerous consequence. The coats of the Bladder are three, 1st: the common coat 2d: muscular and 3d: Villous, the muscular coat at the neck of the Bladder is thick & circular and is called Sphincter. The Ureters enter the Bladder one on each side about an Inch from the neck thereof by a small Orifice obliquely. The situation of the Bladder is between the Rectum & Olsa Pubis in men and between the Uterus & Pubis in women its use is a Reservoir to the Urine Parts of Generation Lect 51st 1st In a Male. These are the spermatic Cord, Testes Scrotum, Vesica Seminales, Prostate Gland, and Penis. The spermatic cord is composed of the spermatic Artery and Vein, Nerves, Lymphatics, & Vas deferens all included in acellular coat and some have supposed a muscular wc. they called Cremaster wc. is not visible except where it passes out of the Abdomen wc. it does in an oblique manner through the rings of the Abdomen, by which the Intestines and Omentum sometimes falls thro' forming an Herniae Inguinalis or Jerotalis along the side of the spermatic Cord The x Caput Gallinaginis The vas deferens empty themselves somewhat like the biliary ducts there being a passage from them immediately into the Urethra, but it commonly regurgitates into the Vesicula Seminales & there kept till used. Vesicula Seminales are two Glands situate under the neck of the Bladder, composed of little cells which communicate with each each other, being reservoirs for the semen, from each of these there goes a small duct which opens into the Urethra at the Caput Galaginis, x where is a large Gland called the Prostate Gland which secretes a fine mucus to defend the Urethra from the acrimony of the Urine. The Scrotum is composed of skin Cellular Membrane &c: next to which has been reckoned a muscle called the Dartos which is not to be discerned discerned, and the first obvious Coat is that wc. surrounds the Testicle much as the Pleura or Peritoneum does the contents within them this is called the Tunica Vaginalis propria Testes, and within that is a coat which adheres to the substance of the Testicle called the Tunica Albuginea, The substance of the Testicle is wholly Glandular, the spermatic Artery entering in at the side of the same and distributed through the same terminating in fine secretory ducts and these again in excretory ducts which uniting into one form the Vas deferens, The Epididymus is an Appendage to the Testicle formed by numerous convolutions of the excretory duct, reckoned 6 times as long as the Spermatic Cord. Lect. 52d: Parts of Generation in Females. These are either external or internal, the external are the Mons Veneris on which hair grows at a certain age Labia or External Lips of the Orifice at the upper part of wc. is a small body called the Clitoris under which in a small groove is the Iter ad Urinam thro' which the urine passes & into which the Catheter must be introduced in a suppression of Urine, & we should be well acquainted with this Orifice as the modesty of women often denies us a sight of the part, so that we must introduce the Catheter by feeling, at the lower part where the Labia unite is formed a Fraenum or Fushet or Foushette. x Iter externum ad Uterum Nymphae are two spongy bodies within the Labia within these in Virgins is a circular membrane called Hymen within these is the Iter externum ad Uterum x Vagina is a membranous substance furnished with rugae by wc. the Penis is more titillated in Coitus, there is likewise many small glands in the Vagina wc. secrete a liquor to lubricate the same and during the Venereal orgasm whether real or imaginary there is sometimes so much mucus secreted by these glands that it has been discharged, in great quantities so as to wet all the external parts, this by some is reckoned the Female semen. At the bottom of the Vagina is the Iter internum ad Uterum, the Os Uteri or Os Tincae. N Between x or young Puppy Between the Fushet and Anus, there is a seam called Perinaeum, this in difficult deliveries is sometimes lacerated by the largeness of the Foetus & it is necessary to prevent this accident for to support the Perinaeum with the hand while the Foetus advances Uterus is a small body situate obliquely between the Bladder & Rectum its coats size near half an Inch thick & its internal cavity very small; the Neck of the Uterus is full of rugae wc. serve to allow the same to dilate for the expulsion of the Foetus. The Os Tincae resembles the mouth of a Tench x situate at the bottom of the Vagina tho' not a continuation thereof the Vagina being inserted x An demande si le corps de la matrice etant renverse, & ayant tente inutiliment va induction, elle montroit quilque disposition a ve gangrener, e il conviendroit pour lors de l’eactirper, apris avoir porte une ligature le plus haut qu’il veroit possible. En parsil cas on ne devroit point balancer de faire cette operation pour empecker que la gangrene faisant du progres du cote des parties interieures, elle ne causat la mort a la malade. L'extirpation de la matrice, quoique rare, never sit point en cette occasion une operation temeraire, son succes etant prour a par plusieurs observations Verdeer's Anal: v: 22 p 66 Rousset, dans son Traite de Partes Caesares, dit qu'une femme a la suite de pluesieurs accouchemens laborieux, eut une precipitation de matrice qui ne pouvant etre inserted round the Os Tincae. From the Fundus of the Uterus there goes off nearly transversely on each side, a tube called the Fallopian Tubes lying loose & growing larger toward the further end wc. is fimbricated. The Uterus is suspended by the ligament lata & rotunda x Ovaria are two glandular bodies situate on each side of the Uterus inclosed in cellular membrane in each of these Ovaria are near 20 small Ova Of Generation This is perfomed per Coitus by the Male’s introducing his Penis into the Vagina, & perhaps into the Os Uteri tho' this is denied by some at which time the parts grow turgid by the venereal Orgasm the Os Tincae opens & receives the male Semen in which are Anamalcules, immediately attended. reduite, se gangrena, & tomba d’elle-meme. La femme ne daigna pas garder le lit, & elle Jouit d’une parfaite vante’ pendant trois ans, au bout desquels, etant morte d'uno fievre continue, louverture de fon corps fid voir que c’ etoit veritablement le corps de la matrice, qui par pourriture s’etoit s’epare de lui-meme Ibidem p168. afterwards the Os Tinca closes During the Orgasm the fallopian Tubes grow erect & the Timbria seize the Ovaria at wc. time some one or more of the Animalcule ascend through the Fallopian Tubes & enter the first ripe Ovum wc. has now burst the cellular membrane by its turgidity, then the Ovum is disengaged & carried by the Fallopian Tube into the Uterus, and the place where the Ovum was in the Ovarium is soon after filled up by a yellowish substance called Corpus Luteum, this I proved by opening a Bitch in the Hornes of the Uterus were 7 whelps in one three & the other four & in the Ovaria were the same number of Corpora Lutea, by alike experiment upon a Bitch opened while the Dog was fastened thereto, for dogs have no Vesicula Feminalis are obliged to remain fastened to the Bitch a a long time while the Semen is excreted and carried from the Testes by the Vas deferens into the Uterus I found that the semen was ejected immediately into the Uterus. Though the preceeding Hypothesis seems incredible and almost impossible, yet it answers all the Phenomena of Generation the best of any system yet advanced: however the subject is extremely intricate & no doubt is one of the Arcana natura which the omniscient Jehovah of his infinite goodness sees fit to hide from us. Lect: 53d. Of the Foetus its Nutrition &c. The Ovum of the female wc. is foecundated in the preceeding manner by the semen Masculinum is supposed to contact also the membranes that envelop the foetus with the Placenta, Umbilical Chord &c: The Ovum lies in the Uterus 9 months, but for the first two or three months the Placenta does not adhere to the Uterus The Chorionis the external coat of the Foetus it is a thick spongy membrane. The Amnios is within the Chorion it is very thin and smooth, between these two membranes some have described another called Alantois wch. includes the Urine of the foetus carried there from ye. bladder by the Urachus, this is found in some brutes but cannot be discerned in the human species The Placenta is made up of a congress of vessels. How does the Placenta adhere to the Uterus? How is the Foetus nourished? is it by the Mouth; the Umbilical Vein, or by both together? Does red blood go immediately from the uterine Vessels of the As first this want of Navel String, 2d: a diminution of the the Liquor Amnii, 3d. Mucus being found in the mouth & stomach & meconium &c: # 1st. A want of mouth or any passage into the chylopoetic organs, 2d a corruption of the Liquor Amnii 3d. That the liquor Amnii is an exudation from the foetus & consequently not fit for its nourishment &c: the mother through the Placenta to the Foetus & vice versa? from whence comes the Liqour of the Amnios? these are question, that have been differently solved by physiologists. Some have imagined that the placenta adheres to the Uterus by its vessels inosculating with those of the Uterus, others imagine there is no continuation of vessels by inosculation from the placenta to the Uterus, but that the placenta adheres thereto by a kind of cement; for (say they) if it adhered otherwise there must be a laceration (& consequently an inflammation & suppuration) wc. does not happen when it is bro.' away. As to the Nourishment of the foetus many have imagined that it rec'd. nourishment by the mouth & bring many arguments to prove it*, on the contrary others deny that the Foetus receives any nourishment by the mouth but wholly by the umbilical Chord - this is the most viewed Opinion, but for a particular acc't. of the Nutrition of the Foetus in Utero side Med: Essays of Edinburgh and Dr. Shippen’s Thesis for the connection of the Placenta to the Uterus A It was the rec'd. Opinion till of late by all who allowed the foetus to be nourished by the umbilical Chord that red blood was immediately conveyed from the mother to the foetus; Their arguments for it are 1st. that if the mother bleeds to death the Foetus will be deprived of blood also. 2d. Injections pass from the mother to the Foetus. 3d. that hemorrhages happen upon a separation of the placenta from the uterus. 4th that the umbilical Chord will bleed a great quantity when cut &c: but the most modern doctrine that now prevails & wc. answers all the phenomena best is that red blood does not pass immediately from the mother to the Foetus, for before the placenta adheres to the Uterus it certainly cannot, & then it must be nourished by absorption of the Placentine vessels as well before as after its adhersion to the Uterus; we have said before that the placenta does not adhere to the Uterus by inosculation of the Vessels, but by a slight cementation, thence we suppose that the the small ends of the placentine Vessels open into the mouths of the uterine ones, and as the mouths of the uterine Vessels are so large near the time of delivery as to admit a goose quill whereas the mouths of the placentine Vessels are so small as not to admit red blood its very probable there are many of the placentine vessels open into one of those of the uterus. These small placentine vasculae are part of them supposed to absorb the chylous & ferrous nutritious part of the blood in the uterine vessels which the placenta forms into red blood before it is conveyed to the Foetus; The manner how the placenta acts in forming this nutritious fluid into blood is unknown, but it is supposed to perform the office of Lungs in that particular. The placentine vessels having absorbed the nutritious particles of the mother’s blood and and the placenta formed it into red blood it is conveyed by the umbilical Vein into the Foetus, for its increase & nourishment, while the superfluous & unnutritious part is reconveyed by the umbilical Arteries into the placenta & is absorbed by the uterine Vessels and mixed with the blood of the mother; thus instead of a reciprocal circulation between the Foetus & Mother which was formerly Supposed, and is still by some, there is only a secretion of the fluids which pass from one to the other. The Arguments brought to Support this new doctrine are, 1st: That upon the mother’s bleeding to death, the Foetus will not be deprived of any of its blood this Dr. Shippen proved by an experiment he made in Edinburgh before Alexander Monro jun'r he bled a Bitch to death then opened her and took out her whelps which appeared to have lost not one drop of blood blood. 2d. That the umbilical Cord when cut will not bleed but very little, no more than the blood contained in the Placenta, this most Midwives know & it is mentioned by Smellie: but 3d. Lastly the greatest argument of all is that Injections cannot be made to pass from the placenta into the Vessels of the uterus nor vice versa tho' it has been repeatedly tried by the greatest Anatomists notwithstanding what has been said by some to the contrary. A Course of Bandages Bandages are very necessary to confine dressings upon any external part of the body, injured either by accident or by a necessary Operation. Lect: 54th: Bandages of the Head. 1st: Handkerchief doubled & made 3 square put round the head & tied behind 2d: Grand Covre Chef a large square handkerchief doubled to ab.t 2/3 the way & laid on the head the single part so as to reach the Nose, the double part the forehead, wc. double part being uppermost must be fastened under the Chin, the other then turned up & tied behind in the nape of Neck 3d: Poormans Bandage of Galen a piece of linen cut into 6 tails & laid on the top of the head, the middle tails fastened fastened under the Chin the hind ones before & the fore ones at last behind. 4th: Capaline a long doubleheaded bandage 4 or 5 fingers breadth wide to put round the head 5th: Uniting Bandage double headed & like the former with a slit near the middle to be applied to a wound of the forehead. 6th: Scapha for bleeding in the frontal vein going several times round the head at last the first end turned over & tied behind 7th: Kiaster double headed for bleeding in the Temporal Artery going several times round the head then twisted round to a hard knot over the Orifice & then part one end over the crown the other under the Chin and fastened. 8&9 Monos- & Bi-Ocular double headed the first covering one Eye the last both Eyes Lect. Lecture 55th: 10 Accipiter a T Bandage for the Nose going round & tail tied over the head. 11 A four tailed sling bandage for the upper Lip. 12 A four tailed sling bandage for the Chin the under half being the broadest. 13 Capistrum double headed bandage passing from under the Chin to top of the head then to neck & round to the Chin &c: 14. Divisive along double headed rowler to keep up the head. Bandages of the Trunk 15 Spica double headed for the shoulder 16 Star Bandage for a fracture of the Clavicle a single headed rowler & if necessary the Capaline may be applied with it for greater safety. 17 17 For the Thorax the Jenriette or Napkin & Scapulier the first going round the body the latter slit going over the head & fastened thereto. 18 Suspensor of Heliodorus for a diseased Breast a X bandage 19 For Paracentesis a broad flannel roller to go round & compress the Abdomen. Lecture 56th: 20 Spica Inguinis double headed for any disorder in the inguen. 21 T Bandage or Suspensor Scroti beside wc. there are several others of less note to these parts particularly the Truss Bandages of the Extremities 22 Deloer for the Wrist 23 Spica Pollicis for the thumb. 24 Gauntlet ~ } for the fingers 25 Denigantlet 26 26 Eight tailed bandage for a broken Patella &c: 27 For a simple Fracture Thypodesmus going round under the splints a single headed roler & Epidesmus going over the splints one roler very long may serve for both. 28 For a compound Fracture where there is a Wound &c: the 18 tailed bandage together with splints Tape &c: and lastly Junchs, Box, or Cradle &c: if it is one of the Legs. A Course of Operations Lecture 57th:~ Of Sutures There has been many sutures invented most of which are out of use. We ought to observe that a wound made longitudinally in the direction of the ~ Fibres requires no sutures be it ever so great, for by means of a bandage the sides of the Wound is easily brought together without suture. But a wound made obliquely or transversely requires a suture as no Bandage can be made to keep the wound together. The intention of Sutures is to bring the likes of a fresh wound in apposition, that the vessels may inosculate & heal by the first intention, the chief sutures are The Glovers stitch, The interrupted suture, The quilled suture, & the Gastroraphy, The Glovers stitch is performed with a strait needle & waxed thread single, turned over and over. The interrupted Suture is made with a crooked needle & single waxed thread the lips of the wound being brought together first make a stitch in the middle the Rule for which is to begin as far from the edge of the wound as the wound is deep making the needle come out at the bottom of the wound & continued thro' on the contrary side then tied not over the wound but on one side, then make two other stitches near each end wc. is mostly sufficient. Quilled Suture is made with a crooked needle as before with a double cord & tied at the end with a quill on each side the Wound. The The Gastroraphy is performed when the parietes of the Abdomen & Intestines are cut. The intestine is to be saved up with the Glovers stitch leaving a piece of the thread at each end to lie out of the wound of the Abdomen, then the Parietes is to be stitched with the interrupted Suture in a particular manner viz: on each end of a waxed cord must be put a crooked Needle, then take one needle & from within the wound push it out then take the other needle & do the same on the other side of the wound, bringing them together & tying the same, do so until you have as many stitches as you think is necessary Of Trepaning When it is necessary to perform this Operation we should consider first the places where the Trepan may be applied; there are 3 places where it is improper to apply it viz: to the Sagital Suture, the frontal Sinuses, & the Os Accipitis. In Operating, an Incision must be made of a good length through the scalp, the same opened & the Cranium scraped, than having fixed upon the place apply first the perforator & after that the Trepan secundum Artem. Of Fistula Lacrymalis This operation is performed when the ductus as Nasum is stopped & has formed in the Lacrymal Sac &c: Sometimes compression alone will cure this disease but when the Operation is necessary its performed by making an incision over the Sac at the bottom of the Orbit & half the length of the same, into the Sac & cleaning out out the matter & if necessary making an Aperture through the Os Unguis with a strong Probe or a Trocar into the Nose. Of the Polypus of the Nose This is an excrescence growing in the Nose in the Schneiderian Membrane, has different degrees of firmness, in a recent state it is very tender but by degrees grows harder until it gets to a great firmness; the best time for extracting it is when its so hard as not to break easily with the Forceps but not so hard as to adhere to the Schneiderian membrane too strongly. Its extracted by taking hold of it with the polypus Forceps & working it to one side and the other backwards & forwards &c: until it is loosened. Extirpating the Tonsils. This is best done by Ligature for fear of an Hamorrhage if the Tonsils are largest at the apex its an easy matter with proper Instruments to pass the Ligature round its basis & make it tight, but, it often happens that the Basis is largest in this case a ligature put round woud slip off therefore with a proper needle it must be run through the middle of the Tonsils & tied on each side cum node Chirurgica &c: Of Amputation Amputation is sometimes necessary but not near so often as has been thought; all agree that it is necessary in a Mortification, but then it must not be performed until the mortification is stopped & even new flesh begins to granulate. In Amputating the Leg we must stand between the legs that the saw may take the Fibula before the Tibia is quite cut off. we We first apply the Tourniquet to the thigh to stop the blood, then with a strait knife wc. is the best we make a circular incision with two cuts round the leg or thigh through the skin cellular membrane & fat about an Inch below where we intend to cut off the Bone, then an Assistant must pull up the skin as high as possible, after wc. the Operator must make a second Incision through the muscles to the bone then if it’s the leg or forearm the double edged scalpel must be run between the bones to cut the interosseous Ligament & Muscles, lastly the bone itself must be cut off with the saw. & then the Arteries taken up &c: The Fingers are Amputated contrary to all other parts at the Joins by cutting the flesh as before then stretching it up & with the scalpel beginning on the side take off the Joint. Of Empiema This is an operation for letting Pus Water or Blood out of the cavity of the Thorax, oftenest Pus, wc. comes from an inflammation & Suppuration, when this is in but small quantities, the Lungs by then great power of Absorption often carries it off by Expectoration as we see in Pleurisies; but when in great quantities the operation must be performed very carefully for fear of hurting the Lungs between the 6 & 7 or 7 & 8 Ribs with a common scalpel. Of Bubonocele This is the dangerousest operation in Surgery, & not to be performed but when absolutely necessary; when so it is done by making a long incision from above the rings of the abdominal Muscles almost to the bottom of the scrotum carefully in to the Intestine thro' the Peritoneum or Herniary Sac then dilate the passage by incision & carefully reduce the Intestine. Of Couching This Operation is performed for the removal of a Cataract or opacity of the crystaline Lens; there are two ways of doing it, the old way of depressing the Lens with a needle to the bottom of the Eye into the vitreous humor wc. is done by running the needle abt. 1/10 of an Inch below the Cornea into the posterior Chamber behind the Iris & depressing the Lens. The other method, wc. is the new way, much in vogue at present, & I think the best is to cut the Cornea & extract the the crystalline Lens. In the Old way the Lens is very apt to use after it has been depressed wc. makes this new way preferable; it is performed by a small knife with but one Edge wc. is to enter near the place where the Needle enters & pushed thro' into the anterior chamber above the Iris (taking care not to cut it) and out on the other side cutting half or better of the Cornea, then with the point of the knife cut the capsulae of the Lens & its easily pressed out. Of Lithotomy This Operation is performed for extracting a stone out of the Vesica Urinariae; there has been several methods invented to perform this operation but the Lateral Operation or that invented by Irene Jaques is the best & universally in use. We are not to operate until we are certain there is a stone in the Bladder & we can feel it by sounding & all the other Surgeons present. In Operating we first tye the patient on a Table of a sufficient height lying on his back by making a noose with a garter round the Wrist then making him take hold of the bottom of his foot with his hand putting the Garter round his Instep & hand in form of 8 a sufficient number of times, with an assistant to hold each knee then introduce the Staff into the bladder, letting a careful assistant hold the same bending the top a little towards the right Groin is as that the bend of the same may turn a little to the left then then the Operator setting down right before the Patient must with a sharp scalpel make an incision immediately upon the staff from the Base of the scrotum to beyond the anus abt. an Inch to the left of Cerines through the skin & fat, (this should be made thus large that we may get at any Artery if necessary) then make the incision shorter down to the staff when we feel the staff bare we must take the Gorget put the point of it into the Groove of the staff then take hold of the staff from your assistant & turn it over while you slip the Gorget along the groove into the bladder, then take out the staff, & introduce the Forceps upon the groove of the Gorget, when they are in the Bladder pull out the Gorget & gently feel for the stone, when you find it take care to get good hold of, it not being in too big a hurry; when you have it fast extract it. If the stone breaks take out what you can with the Forceps & the rest with a scoop. The wound must be drest gently wth. dry Lint. Med. Hist. MS. B 158 Of Tapping Of Injections The ancients used to employ only Ink for Injections (which answered the end but very poorly) until the time of Ruysch who made his injections of wax, some of wc. have since been improved; his method of Injection was as follows viz. He first laid open the hypogastrium & made two incisions about an Inch long into the Aorta & Vena Cava, then put the Subject in cold water several days pressing out the blood frequently. Next he put them in warm water several days more & put two tubes in the Artery one upwards & one downwards & fastened them tightly. His injection was only simple Suet calomel with Cinnabar in cold weather & in the Summer time he added a little white wax & injected it gently when warm into the vessels, then put the Subject into cold water till the injection was cold, then dried the preparation carefully or preserved it in spirits of wine Injections used by the modern are the follg: Corroding Injection of Dr. Nicholls Rx Wax 4 ounces Resin 3 ounces when melted add Turpentine Varnish 3 ounces Dr. Hunter's Corroding Injections Rx Wax 3 ounces Resin 3 ounces when melted add Venice Turpentine 11 ounces Another Rx Wax 4 ounces Resin 3 ounces when melted add Oil of Turpentine 2 ounces Another Rx Wax 4 ounces Resin 8 ounces or 10 ounces Tallow 3 ounces melt them together The Injection is known to be of a proper consistence by dropping some of it when melted in water & when thoroughly cold forming it into the shape of the Vessels if upon Landing it breaks it is too hard if it bends easily it is too soft & must be mended. Those Injections which have Turpentine Varnish, Venice Turpentine or Oil of Turpentine in them must be tried as above every time they are heated because in heating they loose of their volatile oil Of the Colours To the foregoing Injections such a quantity of colouring matter must be added as will give them a bright colour which must be determind by the Eye Colours generally used are Vermillion Kings Yellow, Blue Verditer & Flake White. Other colours may be used. They are generally to be mixed with the Injections when they are melted; but there are some objections to this rule in some of the colours particularly the blue Verditer & in some measure the Flake White for Navy both ferment when mixed with the foregoing Injections; to prevent which it is necessary to melt some of the Ingredients alone & add the colour to it before the other Ingredients are added. The following Experiments will particularize these Exceptions 1 Blue Verditer with Tallow alone causes no Fermentation 2 Blue Verditer with wax alone don’t Ferment 3d. Blue Verditer with Resin alone does ferment, therefore mix the blue Verditer with the Tallow or Wax alone or together & afterwards add the Resin which causes a small froathing If Turpentine Varnish, Venice Turpentine or Oil of Turpentine be used mix your colour first with the melted wax & then add either of these Ingredients with the Resin These observations are equally true of the Flake White When we make a white Injection instead of yellow Wax we use white. It would seem that we have not yet any Green Colour, but as blue & yellow make a Green the blue Verditer added to the yellow wax or Resin gives us a fine green Dr: Nicholls fine Injection Rx Hard Brown Varnish & hard White Varnish a 5 ounces Turpentine Varnish 2 ounces add the Colour & shake the Vial first putting some shot therein to make them mix. Either of the hard Varnishes will do as well as both adding the same proportion of Turpentine Varnish viz 1 to 5 Another Rx Hard Brown Varnish & hard White do. a 8 ounces Venice Turpentine 2 1/2 ounces mix these as the former If we neglect being nice in our proportions or from often heating these Injections become too hard or Brittle. We know when they are of a proper consistence by the following Experiment; Drop one drop of it upon cold water which will immediately diffuse itself over the whole surface when the spirit will be immediately attracted by the water & the gums with the Turpentine will be left swimming on it, if this will bear raising up without breaking it is of a proper consistence, but if it breaks its too hard & much be softened till it is properly tenacious Of Watery Injections Glue dissolved in water alone makes a good minute Injection; before it is dissolved by heating its necessary to steep it in water for 12 hours then boil it upon the fire till the whole is dissolved, afterwards strain it & drop some of it upon a cold stone or any cold substance to cool that you may know its consistence; when it is somewhat thicker than a common gelly it is of a proper consistence Isinglass & water prepared in the same manner as the preceding ~ makes an Injection similar to it Gum Arabic, Tragacanth, or any of mucilaginous Gum dissolved in Water to the consistence of Cream & strained as the preceeding make a very minute Injection As the Colours mix difficultly with with these watery Injections, they ought first to be mixed well with a little of the Injection & then the remainder added to it. Of Oily Injections We often make Injections of almost all Oils as Oil of Turpentine Hogs lard Tallow &c: The oil of Turpentine is rather too thin of itself but when added to two parts Tallow is a good Injection Butter or Hogs Lard make of themselves a pretty good Injection All fine Injections require more Colours than coarse ones, for as it is to run into much smaller vessels it of course becomes more & more transparent and therefore requires such a quantity of colour as to render it opaque even when it is most minutely separated on diffused within in very small vessels or on any surface Of Common Injections The corroding Injections are too hard for several purposes & the fine ones too soft therefore we need something between them, some of which must be softer than others The hardest is Rx Resin 3 ounces Tallow 2 ounces Wax 1/2 ounce Colour sufficient for an Injectn. is Rx Resin 2 ounces Tallow 2 ounces Colour sufficient for an Injection These are generally used when the part is intended to be dissected Varnishes Turpentine Varnish Yellow Resin 14 lbs Oil of Turpentine 16 lbs, boil the water out of the Resin & then add the Oil of Turpentine from the fire. White Hard Varnish Mastich & Gum Juniper a 1 grain Alcohol 8 grains ~ Brown Hard Varnish Shell Lac & Seed Lac a 1 1/2 grains Gum Juniper 1 1/2 grains Alcohol Galls. 2 clean the Gums from dirt & bruise them pretty small then put them in the spirits & dissolve them in a Sand heat The Spirit of Sea Salt is the corrosion commonly used by Anatomists The part to be Injected must be macerated in water blood warm 2 or 3 days so as to relax the vessels & soak out all the blood in them, then having a proper sized Syringe with pipes of different sizes, fit one of the pipes into the vessel & fasten it well with a ligature bringing the ligature round the cross piece to secure it the latter. The part to be injected lying in the warm water & the Syringe and Injection being warm, the Syringe is to filled with the Injection, the end of it put into the pipe & kept fast & the Embolus of the Syringe pressed gently down with the breast till the part is sufficiently injected or the syringe when it is to be filled and emptied as before if necessary ~ Med. Hist. MS B 158 Med. Hist. MS. B 158 Ex Libris Jonathani Elmer Ipromet manu Jeripris Jonathn. Elmer’s A Course of Anatomical Lectures Delivered By Dr. William Shippen junr. Professor of Anatomy & Surgery in the College of Philadelphia Anno 1766 Quanta autem existerent consilii solertissimi indicia, su tota hominis fabrica perspecta foret? si corporis totius species et dignitas? Sensuum organa subtillissime fabricata, et aptissime locata. Synop: Meta: Anatomia fundamentum est Medicinae Anomal Anatomical Lectures Lecture 1st: Anatomy avatouia in Greek signifies cutting & by it antiently was meant only the dissecting of bodies, but at present it is implied in a more general sense. Anatomy in respect of its object is divided into human and comparative. Human Anatomy is that which is employed on the human body; and comparative Anatomy is that which is employed upon the bodies of other animals, these serving for the more accurate descriptions of several parts, and supplying the defects of human bodies. Anatomy from its various ends may be said to be of four kinds viz: Theological, Medical, Juridical, and Judicial. The The first consists in an acquaintance with the works of the creator in the human frame; according to Fontanel the study of Anatomy & Autonomy afford the strongest arguments against Atheism. Medical Anatomy is ultimately health, for the presentation of which, restoring it when impaired, by diseases, or even preventing their access, nothing surely is more necessary than a true knowledge of the structure of that frame so liable to be injured. Juridical Anatomy is the determining the causes of suspicious deaths, impotency, barrenness, the true times of pregnancy and delivery, the mortality of Wounds and a multitude of other causes of great importance to be adjusted in account of Judicature. Judicial Anatomy is the determining the cause and manner of the death of diseased persons from a subsequent dissection of the body body; this is of the utmost use in the practice of Physic. Upon the whole then the use of Anatomy in very great, nor is it confined to the bounds of Medicine alone; the Philosopher and Theologist, the Magistrate, Painter and Sculptor are in their respective employments more or less qualified in proportion to the progress they have made in this science; but the physician and Surgeon are the people to whom it is most immediately necessary and who without a perfect knowledge of it cannot do justice to the world in their professions. What the needle is to the mariner, Anatomy is to both these, and we may venture to say that without its assistance, they would be rather detrimental than beneficial to mankind. The Anatomy of the solid parts is by Heister called Osteology and that of the soft parts Sarcology, each of these are subdivided. Osteology or the anatomy of the Solid parts is divided into the anatomy of the Bones called Osteology; Chondrology or the anatomy of the Cartilages; and Syndesmology or the anatomy of the Ligaments. Sarcology or the anatomy of the soft parts is divided into Dermatology or the anatomy of the Teguments; Splanchnology or the anatomy of the Viscera; Myology or the anatomy of the Muscles; Neurology or the anatomy of the Nerves; Angiology or the anatomy of the Veins and Arteries and Adenology or the Doctrine of the Glands. In the human body as a complex hydraulic machine a double inquiry must be made 1st. Into the structure of the parts, this is called Anatomy, 2d. Their functions & the laws of their motion which is termed Physiology Lecture 2d. As the solids are formed out of one principal fluid chiefly, called the Blood it is proper to begin therewith. Of the Blood Blood in Scripture is called the life of the Animal; according to some it is the primum vivens ultemum moriens, its a heterogeneous mass, as is evident from the variety of ingredients of which it is made up, and the various forms it assumes in the animal machine. The blood is composed of three substances viz: Serum, Gravamentum & a coagulable Lymph: We shall consider these in three different manners; first when ocularly examined, 2d. Viewed with a Microscope, and B 3dly: The chemical Analysis thereof. Blood fresh drawn from a sound living animal, upon landing, part of it congeals into a hard coagulum suspended in a yellowish Serum, the upper surface being of a florid color while the bottom is black; the reason of the blood appearing bright and florid at the top is from its being in contact with the Air; this is confirmed by an experiment of Dr. Hunter’s who put a quantity of blood fresh drawn into a vial, & stopt it close; upon standing it all turned of an uniform black color, except a little spot upon the top with which a globule of Air had got in contact. Blood stirred round with a probe whilst Whilst warm, a fibrous elastic substance is obtained, which, put in water turns of a whitish color; this is the coagulable Lymph, is strongly elastic, & is the cause of cohesion in the particles of the Blood, as is evident from the extravasation of the blood after death by dissolution of the cohering particles. The coagulable Lymph is sometimes discharged from the Uterus and by Nurses taken for an Abortion; this error they are sometimes led into from a desire that it should be so. If spirits of Wine be added to Serum, or the same made boiling hot, it rises up, emits fumes, and turns into a coagulum similar to the White of an egg: the fibrous part of the blood is what forms Polypuses Polypuses concretions &c: Blood viewed by a microscope appears to consist of a number of globules, the larger ones being those that tinge it of a red color, &c: therefore chiefly make the crassamentum, are of a certain determinate magnitude being of the same bigness in all animals, in a Sheep as in an Ox, in an eel as in a man. These globules are composed of six smaller or ceruminous ones; and these ceruminous ones are composed of smaller or lymphatic ones; and it is probable there are still lower orders of globules of blood. These globules of blood are of a lenticular form and elastic the largest kind being less than the 1/3000 part of an inch Inch. the crassamentum is supposed to contain 1/3 of the mass and the Serum to make up the other 2/3. Blood chemically analyzed; upon distillation with a slow fire a quantity of Phlegm arises, with the fire increased next arises an Oil and a volatile Salt, the caput mortuum being a fixed alkali and a cretaceous Earth. The chemical proportions of the blood are by Dr. Martin & Boyle recvd. as follows viz: of Phlegm 5/6 of Oil 1/15, of Salt 1/25, of Air 1/20, & of Earth 1/75, part of the whole mass. The specific gravity of the blood to that of rain water is by Dr. Jurin and and Martin reckoned as follows, by Jurin as 1000 to 1054 by Martin as 1000 to 1056 or 1057 or as 10 to 19. The density of blood in living animals is to its density when reduced to the coldness of temperate Air as 134 to 135 or 992 1/2 to 1000. The color of blood is for the most part red, but redness is not a constituent quality in blood, for some Animals have white blood. In the human body the blood is redder & more florid in the Arteries than in the Veins, oweing to the action of the Lungs upon it, for by shaking fresh blood in a vial taken from a vein, it appears of the color of arterial blood. That the blood is is reder in the Arteries than in the Veins. Dr. Hunter proved by the following experiement: he opened the Thorax of a live Dog and kept his Lungs working with a pair of Bellows; and drew a spoonful of blood from each side of the Heart is, from the Vena Cava & Aorta the latter of which appeared the reddest. From the accurate experiements it is found that a cubic inch of rain Water weighs 253 1/3 grains, a cubic inch of warm blood 264 3/4 grains. An Ounce of Blood contains 1,813 Inches, an avoirdupois ounce weights 437 1/2 grains equal to 1,727 inches of water and 1,6526 of warm blood. Lect. *Among these we may reckon Boerhaave instit. vol. 2 the colour of the Arteries are of aligamentous substance and not muscular as is evident from their white appearance and their of elasticity both of which is contrary to the general characteristic of a muscle however we are informed that Dr. Cullen has lately discovered that there are muscular fiber in the coats of the arteries the action of which he thinks assists in propelling the blood onward. J. Cullen likewise says that there is a muscular coat to the arteries as well as Boerhaave & many others. &c physiology [illegible]. Lecture 3d. Of the Arteries & Veins An Artery is a strong, membranous, ramifying, elastic Tube, endowed with pulsation; arising from the left side of the Heart, and terminating in every part of the body. The Arteries are composed of three coats, tho’ some have reckoned four and some five.* The first external coat is very thin the fibres of x which going longitudinal & circular; the second coat is thickest and the fibres of it go in a circular direction; the 3d. coat is very compact and its inside very smooth and even, this smoothness and compactness of the inner coat serves two purposes. 1st. to allow the blood to to pass without hindrance & 2d. to prevent its exudation. The pulsatory motion of the Arteries is a dilatation and contraction of them; the former called Diastole, and the latter Systole, which precedes proceeds from the Heart, besides which they have a sort of aperistaltic motion, as is evident from an experiement of Dr. Hunter’s, who opened alive Dog and cutting off the mesenteric Artery, injected it wth. a warm milk, which he could plainly perceive the Artery to carry along wth. a vernicular motion; to confirm is the more he injected the mesenteric Vein but the milk went no farther than the & the force of the injecting propelled it. There are but two Arteries in the body viz: the pulmonic, which carries the blood through the small circulation, and the Aorta, which carries it to all the parts of the body. The coats of the Arteries are very elastic, and are furnished with blood vessels for their nourishment; the Arteries mostly and all except the Epigastric ramify at acute angles. The commonest diseases the Arteries are subject to, are, Aneurisms and Ossification. Aneurisms proceed from a preternatural dilatation of the coats of the Artery’s and are of two kinds 1st. When the blood is x it is sometimes found in young subjects and is oweing perhaps to a disposition of the constitution to form bony matter. is contained within the coats of the Artery. 2d. when the Artery is burst & the blood extravasated into a membranous bag. Ossification happens mostly to Old people from a weak & slow circulation of the Blood. x Veins are elastic, ramifying Tubes, like the Arteries; except smaller. their coats thinner, and without motion. Phisiologically speaking the Veins begin at the extremities of the Arteries, or more properly speaking they are a continuation of the Arteries reflected back toward their Origin the Heart; but anatomically speaking the Veins arise from the Heart. There There are 7 Veins in the body from which all the rest arise viz: The 2 Venae Cava ascendans and decendans; 4 pulmonary Veins (two from each lobe of the Lungs) and Vena Portarum. The veins are mostly ramified in the same manner as the Arteries, exct. the Vena Portae, and the cutaneous Veins of the extremities, & other parts. The veins of the extremities have valves, but not those of the Viscera; the reason of which is because there is no Muscles in the viscera; hence the use of those valves in the Veins of the extremities is to prevent the blood from going backward as well as x Bellini especially is of this opinion as well as for, to push it forward when the muscle is contracted and the Vein compressed. Of Venesection & Hemorrhages. In bleeding, the blood is supposed to x flow out faster at the orifice than it circulates in common, and to increase the circulation to the part, hence the doctrine of revulsion & derivation is easily understood; thus we find in a Cephalalgia bleeding in the foot causes a derivation to the feet and a revulsion from the Head &c: In Hemorrhages the antients used Ligatures round the joints, wc. stopping the return of of the blood to the Heart checked its impetus, but but by Venesection his ends are answered: e,g, supposing an Hemorrhage at the Nose, Lungs, Uterus &c: bleeding takes off the impetus of the blood & causes a revulsion, at the same time. Dr. Haller thinks this latter method much the [illegible] the Veins are some of them subject to Varices, which are an obstruction, or destruction of the valves thereof. The muscular coat of both the Arteries and Veins are somewhat subject to inflammation & suppuration, but not near so much as the other muscles of the body; this is very wisely adapted to their function, for suppuration of their coats would be attended with fatal consequences often. Lecture Lecture 4th. Of the Lymphatics. Lymphatic or absorbent vessels are those fine ramifying vessels which contain a clear diaphanous Liquor; they take their rise internally from the cavities, as the stomach, intestines, and externally from the surfaces of the skin. The antients supposed the Lymphatics were a continuation of the Arteries dividing them into three classes, sanguineous, venous, and Lymphatic, but, it has very lately been discovered that the Lymphatics are an entire system of vessels by themselves, having no affinity or communication with either the arteries or veins. this This is proved 1: by injections not passing into them from the arties 2: by the motion of the fluid in them and the valves they have; they are called absorbents from their office, which is to absorb the Lymph and other matters and carry it into the thoracic duct or Receptaculum Chyli; where they are all supposed to terminate. Those vessels called lacteals belong to this system; and called Lacteals only, from their carrying a milky chyle: their origin termination and course of their fluids being the same. That the lymphatics are absorbents is evident from their absorbing moist substances rubbed on the skin, as Mercury, Turpentine, Garlic &c: but in a more obvious manner in the venereal Disease, where absorbing D the virus they carry it to the adjacent Lymphatic Glands and cause them to tumify, hence Buboes &c: sometimes the virus causing the glands to tumify and inflame, constricts the vessels beyond the same and prevents the infection from going any farther; hence the cure of the venereal disease sometimes by the suppuration and discharge of a Bubo. Of the Glands. A Gland is a secretory Vessel — the antients called only those Glands which we feel hard movable kernels under the chin and other were until Malpighius by his microscope found the Liver and other substances to be of the same texture, and therefore termed them all Glandular. A A Gland he thought to be made up of little fine round bodies consisting of Follicles which contained the secreted fluid and between which was a parynchemical substance; but Ruysch by his injections found that the Glands were vascular or made up of fine vessels which has been further confirmed by later anatomists. The vessels of the Glands are Arteries, Veins, secretory and to some excretory Vessels Nerves & lymphatics Of Secretion Some have imagined that the secretions were performed by the diameters of the secretory vessels, supposing them to be of the size of the particles secreted; but this theory is subject to these two objections, viz: that the smaller particles will will go off with the larger ones and to the secretion be confounded and in a Jaundice, when once the Bile had got into the Blood it would continually remain [illegible] & the Jaundice could not be cured; others supposed a particular fermentation happened in the veneral glands, & from thence arose the difference in the veneral secreted fluids, and likewise was the cause of the secretion; this theory is liable to the same objections with the former, and therefore the most received opinion is, that the secretions depend upon the particular disposition of the vessels, to the particular fluid it is to secrete; hence arises these Axioms. 1st. That the secretions are carried on uniformly in a living sound Animal. 2d. One secretion increased another is diminished &c: Lect. Lecture 5th. Of the Muscles & Tendons. A Muscle is a fleshy, fibrous, [crossed out] substance, consisting of Veins, Arteries, & Nerves; besides fleshy fibers &c; having more nerves in proportion than another part of the body serving to give notice to the brain of any external stimulus or irritation. The redness of the muscles is not inherent in the fibres thereof, but only oweing to the blood contained in them, of which there is a great quantity, more than is sufficient for their nourishment and may possibly be subservient to their motion. A Tendon is a white compact fibrous unelastic substance. most muscles terminate in Tendons, and the Tendons are by some reckoned a continuation of the fibres of of the muscles to which they belong, only more compacted together so as not to admit the red globules of blood between their interstices: but Dr. Hunter thinks the fibres of the Tendons are not a continuation of those of the muscles, but distinct fibres someway cemented thereto. The muscular fibres are cemented together by the cellular membranes and an intervening glue, & serve for the moving of the solid parts of the body. The Tendons are for the better insertion of the muscles, and of great use in motion; eg: in the Perforans and Perforations of the hand, the muscle arises from the inferior part of the Humerus, and if that was continued down to its insertion muscular, it would render the hand troublesome some and unwieldy, whereas now, the Tendons, being compact & taking up but little space, remedy that inconvenience. Round many of the Joints as the Wrist Ancle &c: there is a capsular Ligament or Frenum which serves to keep these tendons in their right places, and facilitate their regular motion; likewise over some of the Muscles there is a tendinous expansion called Aponeurosis, of much the same use as the preceding Ligament. The muscles may be reckoned of three kinds first Oblong as those of the Arm, 2d. Convex as those of the Heart, Stomach, Bladder &c. 3d. mixt as those of the Abdomen the Pectoral muscles &c: Muscles have their names from their Origin, Insertion, Use Appearance &c: Lect Lecture 6th. Of the Nerves. The Nerves are now by every body allowed to be a system of the vessels, and they are a fasciculi of white fine fibres, arising from the Medulla Oblongata & Spinalis, egressing in pain. Over the Brain are the Meninges, or, 1st. The Dura Mater which is externally, & a thick vascular substance within this & adhesive to the Brain is, 2d. The Pia Mater, which is a thinner membrane; between these two, some anatomists reckon another membrane, extremely fine & reticular which they call Tunica Arachnoides. The Brain is divided into three portions called, Cerebrum, Cerebellum, and Medulla Oblongata, the latter being being continued thro’ the spine of the back is called Medulla Spinalis. The Brain is supposed to be vascular, & its substance of two cortex; external of an Ash color is called Corticalis; internal of a white color called Medullaris. The Nerves are of the same substance with the Brain, and are properly aportion thereof continued to all the parts of the body. The Nerves as they arise in pairs soon after decussate, or change sides as in the Optic Nerves, the left going to the right Eye, & the right to the left; hence a wound, on one side of the head affects the contrary of the body. The Nerves are distributed thro' the body in much the same manner as the Arteries; the one proceeding from the Brain the other from the Heart, but with this difference & difference, that the trunks of the Arteries grow less the more they are ramified together with the ramifications ad infinitum; but the capacity of a constituent Nerve never decreases they being imperceptible, but the number of the likes of the Fascicule decreases in proportion as the bundle ramifies, thus the cords of the Nerves wc. as they egress from the Brain contain an innumerable number of constituent Nerves, decrease in No. but not in capacity ad infinitum in proportion as they are ramified. The Nerves anastomose, but not in the same manner as the blood vessels do, by uniting their tubes but only by their coming in contact with each other; these anastomoses are called Plexuses. sometimes little knots appear in Nerves called Ganglions, some imagine these knots proceed from pressure & inflammation, but this cannot be as they are found found in the Viscera, & in a Foetus where no pressure could happen. Lancesi, reckons the use of these Ganglions is for an an additament to the Brain; because he says more nerves go from them than go to them, but from the substance of these knots not being the same wth. the brain, that cannot be. others think they serve to stop the nervous fluid from flying out at the end of the Tube without the impulse of the will by means of muscular fibres, they being only in those nerves destined for voluntary motion; this also appears to be false. The termination of the nerves is but little known, but supposed to be in every part of the body. The use of the Nerves is for sensation, motion, nutrition, &c: the Brain being called the sensorium Comune to wc. the Nerves carry all the sense communicated to them Voluntary Voluntary motion is acquired by experience, as is evident from a child whose will is frequently contrary to the Act performed. Of the cellular Membrane. The cellular membrane is of two kinds, the one adipose containing fat, the other reticular without fat; it is a net like substance, vascular, very thin and tender, consisting of many cells & its fibres very fine: the cellular membrane is continued throughout all the body, except some of the viscera & is called by some the membrana Musculorum Comunis. The cells of the reticular part of the cellular membrane communicate with each other, as is evident from an Anasarca which is a transudation of Phlegm into the cells, & so from the one to the other, as is evident from the Legs swelling by walking & subsiding when lying down x See the Londn: med: observations vol: 2 down; hence Eccymosis from a false Aneurism, Diaeresis, Contusion &c: by which the blood insinuates itself into the cellular membrane; hence also the great quantity of water evacuated from a scarification in an Anasarca. An Emphysema is a remarkable proof of the communication of these cells; this is caused by the air distending these cells & often happens from a fractured rib puncturing the Lungs by w.c the Air gets into this membrane; a remarkable instance of this happened in London, by w.c the patient swelled to that degree that his eyes could not be seen; Dr. Hunter x made a puncture at the Eye by w.c the air gushed out, & by puncturing & rubbing he was cured. Putrefaction will cause an Emphysema, from the fermentation generating air; hence hence a drowned person will after a while rise to the surface of the water. The fat contained in the adipose cells differs in different bodies; in a Foetus the fat is soft, and gelatinous; in children of a year or two old, the fat is chiefly next to skin; hence the fatness observed in children; & in adults the fat is solid and mostly internal. The cellular membrane serves for easy smooth motion, for a defence to the body, to keep the parts warm & preserve the figure of the body, & blunt acrimony. some animals we reckoned to be nourished in the Winter by their fat. Lecture 7th Of the Bones. Here we shall, 1st. describe the external conformation of the Bones, 2d. examine their internal structure, 3d. their connection, & 4th. Explain their use. A Bone is a hard fibrous compact substance. various Bones have various shapes & conformations, some are cylindrical & long, others flat, & broad, irregular &c: bones are said to be made up of Fibres forming Lamellae, fastened together by means of oblique or transverse fibres. Bones have processes and Cavities. Processes have different names from their different forms, & appearance: thus, a Condyle is an oblong process arising from the extremity of a bone; a Corone is an oblong process process terminating in a point; Spine is the sharp ridge of a Bone; Supercilia is a brim round a cavity; a protuberance is a rough process of a bone. Processes are of two kinds viz Apophysis, & Epiphysis; Apophysis is a process growing out from the body of a bone. Epiphysis is a process growing to the body of the bone, being originally separate therefrom by a different Ossification. The cavities in bones are of two kinds, one for Articulation, & the other for the lodgment of soft parts; cavities for Articulation are of three kinds, 1st. Round & deep called Catyloid, 2d. round but superficial called Glenoid, and 3d, deep & narrow called Alveoli, the Articulation of Bones is by Galen called [illegible] Joint & by him is reckoned of 2 kinds, 1st. With motion called called Diarthrosis. 2d, without motion called Synarthrosis; each of these are of 3 kinds. Diarthrosis, are. 1st: Enarthrosis, 2d: Arthrodia, 3d: Ginglymus. Synarthrosis are, 1st: Suture or Raphe, 2d: Harmonia, 3d: Gomphosis. The connection of bones is termed their Symphysis, & is of two kinds: the one wth. and the other without an intervening substance: the first is that of the Cranium by mutual Indentation. the second are of 3 kinds viz: Synchondrosis, Syneurosis & Sysarcosis. Periosteum is an elastic fine membrane, that covers the bones except at the joints teeth &c: its case is for the insertion of vessels, to strengthen the Epiphysis &c: the cylindric bones are all hollow, & so are most others & contain Marrow, the ends of the bones are cellular. F Lect. x see Edinburgh med: Essays. Lecture 8th Osteogonea. In a Foetus, the first months, there are no bones, nothing but a gelatinous fluid; then it gradually grows cartilaginous, & in time becomes boney; some imagine Bones are formed of Cartilages only by an expulsion of the redundant fluids; but Dr. Nisbet x says, & it is now general recd., that in Ossification, there is in the blood, or a fluid secreted therefrom, an ossifying juice; consisting of particles wc. are not apparent; that wherever nature designs an ossification between membranes, or a cartilage she occasions a more than ordinary afflux of fluid which distends so much the vessels wc. were before invisible as to make them capable of receiving the red globules of blood wc. is always to to be seen near to where ossification is begun. In this blood gritty particles are to be felt by the point of a knife, which have been formed by the attraction & cohesion of the particles of the ossifying juice obstructed along with the other grosser fluids in the beginning of the vessels, prepared to receive the influent juices. The membranes or cartilages some as alied between wc. or within wc. the bony particles are deposited or shoot; but without any any intermixture of the particles of the bone & cartilage, or continuation of the fibres of one substance to those of the other as is evident in bones made perfectly clean, the cartilage dropping from it as easy or easier than an acorn from its cup, & there is a smoothness of the parts of both cartilage and and Bone which show that there is no conjunction or union of the fibres of the two substances. While bones are increasing within Cartilages, the cartilages are extended & spread out, by wc., with the pressure they suffer & the great influx of various fluids, & the nutritious matter being kindred to flow freely into them, they decrease continually & at last may truly be void to be entirely destroyed. Bones digested in Acids for sometime grow flexible & gelatinous like a tendon, by which it appears the great quantity of Earth they contain makes them hard rigid. Bones are furnished with Arteries and Veins, as is evident from the drops of blood blood seen in sawing bones lengthwise, & upon their appearing tinged of a red color after the animal has eaten Madder. Dr. Havers divides the blood vessels into sanguiferous, & medullan the latter enter the bones mostly near their center in an oblique manner. Bones have Nerves as is evident from their exquisite sensibility where amputated, or exfoliated, & granules of flesh have sprouted out. Diseases of bones are 1st: a softness & rickety disposition. appearing generally from [illegible] to the 3d. year after birth, though the habit may continue thro' life. It seems to be owing to an Idiosyncrasy or a want of bony matter in the constitution. Sometimes it is said to arise from the pox & scurvy, but probably less frequent than from the other cause. We have the history of a species of Scurvy in France that affected the Bones & separated the Epiphysis. In Anson’s voyage we are told the Callus of bones wch. had been fractured & united again for may years were disposed by this Scurvy ~ Softness from a venereal Taint can be nothing more than a Caries of the bone. the disease first affecting the Periosteum & then communicating itself to ye. subject bone. As to softness from Idiosyncracy as its called; or from a particular state of the solids & fluids. Mr. Goodye furnishes us with a history of a woman whose bones without any apparent cause grew soft; her body shortened, & at last she died, & he found that he could easily cut through the limp bone & all. The academy of Paris give a more remarkable history of a woman whose bones were so soft that at length they had not solidity enough to gird the muscles action—no kind of a scorbutic or pocky taint could be observed. see Vanss 4h:423. Mr. Gooch had a case of this kind under his care, when the patient died he found the bones so soft that he split the thigh bone, the Tibia & bones of the foot the whole length very easily with his knife. Dr. Tilton of Dover relates the like Bones may likewise loose of their bulk like other parts from a loss of juices as in alveolar & vessels of old people. 2dly: Fractures. All bones have a tendency to unite again after being disjoined w:ch is effected by means of a Callus this was formerly supposed to be unorganized, but is now known to be vascular by injections & being tinged with madder. When a Callus is broke it will unite again only to the opinion of some authors. A pupil of Dr. Haller’s in a Thesis he wrote on the subject say that the Callus is first a bloody matter, then slimy, next gelatinous & then vessels from the bone & meditullium shoot out thro' it & ossifications begin directing themselves quaquavenum & thus the Callus Lecture 9th Of the Cartilages & Ligaments. Cartilages are compact, opaque, & a little elastic: of wc. there are 3 kinds, 1st: such as supply the place of bones as the Nose, Trachea Artena &c: these preserve the structure of the part & admit of motion. 2d. such as supply the place of bones before they are formed as in a Foetus. 3d. such as serve for the Articulation of bones. Cartilages differ from bones in not having Fibres nor blood vessels to be siphoned, tho’. they are imagined to be vascular; they serve at the Articulation by their smoothness to prevent abrasion; they won’t granulate nor exfoliate but may be corroded. Ligaments is compleat. sometimes the bones won’t unite but with great difficulty. 3dly: Caries. A caries in alone is similar to an ulcer in the flesh it has circulation but it is unsound & often shoots out irregularly as the fungus of an ulcer See more so in med:[illegible] 2:h:k0 [illegible] [4?377]. 4thly: Spina ventosa – this is a caries beginning on the inside of the bone & affecting it clear thro', hence Surgeons bow into the bone to let out the matter, but in general the limb is to be taken off. See Van Swieten 4 p 377 A node by some is said to be an Exostosis of the bone, but for the most part if not always it begins in the Periosteum. should be open'd before it affects the bone 5ly: Anchylosis is a stiff joint having little or no motion. from the bones running into each other & the cartilages being eroded. Van swieten vol 4 p 457 gives several curious cases of Anchylosis of all the joints in the Body. See also Le Bran’s Surgery. x where it covers the Cartilage. it is calld. Perichondrium the external lamina of the capsular ligament goes from the substance of one bone to the other over the articulation & is inserted beyond the Epiphysis &: Friction 6th. Exostosis is a tumefaction of a Bone or an excrescence growing out of the bone. It may proceed from a redundancy of ossifying particles in the system or in the part only from a morbid cause see Van swieten 4 p 424. See the case of 9: Scott of the Pennsylvania Hospital in my Adversar: med: See Cheselden p 5. Ligaments are firm, compact, unelastic, membranes; serving to connect the joints, prevent luxation &c: The Ligament, Bones, Cartilages, Tendons & Dura Mater are now reckoned none of them to have much sensibility in a natural state. v: Whytt & Haller The capsular ligaments are very strong & compact, & made up of hard Lamella, the inner lamella being a reflected membrane going over the head of the joint. cover the Cartilage x & so coming to join the external lamella, which is firmly inserted near the joint. These capsular ligaments forming a sac in wc. is contained, a mucilaginous liquor serving to lubricate the joint: for for in all Joints; for motion there are synovial glands which discharge the above synovia, this is subject to be disordered: 1st. to become thin & Icorous, 2d thick and inspissated &c: It is generally received of late, that the capsular ligament is lacerated in a Luxation of a joint unless from internal cause, or a relaxation; & violent extension is unnecessary in reduction of the same; no more being necessary than to bring the ends even, and then coax them into their proper places, & there keep them by proper dressings & bandage. For as particular description of the Bones vide Monro’s Osteology, and of the muscles Douglas’s Myographia Lect. 40th: In the Osteology we divided the body into three parts, viz: Head, Trunk, and Extremities; the Trunk of the Skeleton we subdivided into, the spine, Thorax, and Pelvis, but in a fresh subject we divide the Trunk differently, viz: into The Thorax, and Abdomen, or upper, & lower belly. The Viscera of the Thorax are only the Heart, and Lungs, & therefore not necessary to be subdivided. The Abdomen is separated from the Thorax by the Diaphragm. The Abdomen by reason of its largeness and the many Viscera contained therein, has been divided into several parts, by imaginary lines, for the readier knowing the particular situation of each Viscus. The divisions are as follows, 1st G 1st. That which lies under the Cartilage Xyphoides, is called Scrobiculus Cordis, 2d. From the Scrobiculus Cordis down to within 2 or 3 inches of the Umbilicus is called Regio Epigastrium, circumscribed, and on each side there of it is called Regio Hypochondrium. 3d. From the Regio Epigastrium to 2 or 3 fingers below the Umbilicus is called Regio Umbilicus, circumscribed, and each side Regio Lumborum, 4th. From the Umbilical Region to the Os Pubis is called Regio Hypogastrium, and on each side the Regio Hiaea 5th. The lowest part is called the Regio Pubis. As we are sometimes called to open the body of a deceased person before their friends, particularly if they died of a violent death; we should endeavor to to do it with regularity & decency. The antients opened the Abdomen by beginning at the Sternum & directing the knife along the False Ribs to the Loins, then along the spine of the Ilium to the Os Pubis; and laying the loose part over on the contrary side. Others begin at the Xephoid Cartilage & make a straight incision down to the Umbilicus, then dividing the incision directing one to the spine of the right, & the other to the spine of the left Ilium, and turning each part back. But the best method is to begin the incision at the Xephoid Cartilage and going straight down to the Olsa Pubis and then another transverse from the Navel to the Loins each way. The Thorax is opened by pushing off the Teguments & Cutting the Cartilages by the Sternum. Lect. All the internal superficies of the cavity of the Thorax, the ribs, cartilages of the ribs & convex side of the Diaphragm except where the pericardium lies in contact wth. it are lined with one continued, thin, nervous, very strong membrane, internally very smooth called Pleura. On the external superficies of this every where is the cellular membrane wc. in very fat animals is often so enlarged with fat as to lessen the capacity of the Thorax & these cause a shortness of breath. The Pleura when it gets round to the vertebra elevates itself perpendicularly lowd. frenum wc. with the one on the other side from a doable pleura called Mediastinum dorsale. The same duplication is made of the Sternum when it is called mediastinum pectorale. The pleura likewise covers all the muscular circumference of the diaphragm above the cellular membrane wc. arising up together with the orb of the septum from the back sternum, from the external membrane of the pericardium wc. is the third cavity of the Thorax in the middle between the 2 cavities of the pleura containing the Lungs & formed a conjunction of them This membrane of the pericardium is lined internally with a thin membrane wc. is a branch of the external membrane of the Heart. The great vessels from the Heart as they pass thro' the pericardium & go on beyond it or move also at above the cellular one from the external membrane of the pericardium. this membrane forming about to the pulmonary arteries & using wc. when they arise at the Lungs is expanded out & forms the extenal coat of the Lungs. Kaan de Perspi Hippocrat. Lect. 41st: Of the Pleura. The Pleura is a fine membrane, which lines all the cavity of the Thorax and is reflected back over the Lungs. There are two Pleura one on each side, like two bladders beginning as we may suppose at the sternum and going round within the Ribs to the Vertebra of the Back, then reflected back upon the outside of the Lung (making the coat of the Lungs) to the sternum; there running in or uniting with the first Fibres of the same and so on the other side; where the two Pleura meet at the sternum; they are not quite in contact with each other, but there is a small space left between which is filled up with cellular Membrane. Of Constat pulmo duplici vasorum genere, aerifero scilict & sanguifero. Aerifera omnia vasa ortum ducunt ex una trachea, quo mox a faucibus intitium capiens, ante oesophagum, descendit, thoracem post thymum intiat; post cavem descendentem & pericardii apicem, as quartam thoracis vertebram, qua est a superiore una tertia pars ipsius pulmonum longitusinis divaricatur. Hujus dein crura tendunt ad utrumque pulmonem, & statim dividuntur, in homine dextrum in tres, sinistrum in binos ramos, qui tune bronchia dicuntur, as totidem pulmonum lobos, quos ubi ingressa funt, disperguntur statim in ramos minores, & minores; qui omnes ad obtusum angulum, respectutrancorum, oviuntur. Remi autum majors ingressi pulmones, pro maxime parte, descendunt, pauci recti procedunt, ubi ingrediuntur; aliivero adscendunt aeriferorum truncorum, & horum ingressum est. quod prater Eustachium meminen observasse video. Ultimi Of the Lungs. The Lungs are Vascular Substances composed chiefly of Air Vessels, and Blood Vessels; the Air Vessels are Ramifications of the Trachea Arteria, and are called Bronchia; the blood Vessels are ramifications of the Vena and Arteria Pulmonalis; beside-which they have an Artery wc. serves to nourish them, called the Bronchial Artery coming from the Ascending Aorta together with Nerves and Lymphatics, and some say also Parenchyma which is perhaps no more than cellular Membrane. Some Anatomists suppose there are little follicles or cells at the extremity of the small Bronchial Vessels, which if there is are not discernable. Ultimi autem ramuli ommitunt cartilagineam indolem, & expanduntur in vesiculas oblongas, membranaceas, cavas, qua Malpighiana dicuntur, ox quibus fiunt area, & lobuli, qui tandem pulmonum lobos efficiunt. Comitantur aerifera hac vasa, in omni decurser, ad vesiculas usque, vasa Sanguifera, qua omnia oriuntur ex arteria pulmonali, qua cordis dextro ventriculs egressa, qua parte superiore ventriculs sinistro jungitur, adscendit, mox se incurrat, arcum facit, & sub aorta decumit. Descendit The inside of the Trachea arteria is lined with a membrane in which are small glands that secrete mucus for lubricating the its internal surfaces; in cold, this means is sucked into great quantity—sometimes inspissated is spit up very thick especially in the morning. Dissection has taught us that this membrane is the seat of that disease in children called the Hives & is found separated from the cartilages – nothing proves so useful in this disease as large doses of 8. I have known 10 g of calom: given to a child 2 years old produced 2 copious stools & disease immediately vanished The Lungs are divided into two Lobes, by means of the Mediastinum and Heart. The right Lobe is divided into three Lobuli by fissures; and the left Lobe is divided into two Lobuli. In a natural state, the Lungs are every were in contact with the Ribs, so that there is no vacuity left. The Trachea Arteria is composed of cartilaginous Rings, which behind are not quite shut but a small membrane between; each of the cartilages are connected likewise by membranes. The Lungs are liable to inflammation, and Ulceration. In inflammation of the Lungs we should use plentiful bleeding, oiluants, fomentations externally and the steams of warm liquors particularly Vinegar, into the Lungs thro' the mouth. x The ventricles are divided by a middle partition called Septum Cordis. Lect. 42d: Of the Hearts. The Heart is a strong muscular substance, situated obliquely to the left side, more than the right; part of the inferior and or Apex in contact with the Diaphragm, and pointing between the sixth and seventh Ribs on the left side; the Apex being likewise nigher the sternum than the Basis. The Heart is the Origin of the Veins and Arteries. There are four cavities in the Heart, two Auricles, and two Ventricles; x one right and one left, at the right Auricle the Vena Cava enters, and at the left: the Vena Pulmonalis; at the right Ventricle the Arteria Pulmonalis egresses, and the Aorta from the left. M x these cordae Tendineae arise from the Carnae Columnae. At the entrance of the Vena Cava into the right Auricle of the Heart are three Valves called Valvula nobilis, and about the middle of the Auricle there is a little knob called Carna Sesamoidea: At the entrance out of the right Auricle into the right Ventricle and two valves called Valvulae bicuspides, connected by sou:e small tendinous cords called Cordae Tendineae x; the internal part of this Ventricle is rough & muscular having many muscular Pillars, called Carnae Columnae which serves for to strengthen the motion of the Heart and to work the blood so as to prevent its concretion & forming Polypuses,- which however sometimes happens. After the blood has passed out of the right Ventricle into the pulmonary Artery it is prevented from returning by three valves Valves named Valvulae Semilunares. There are likewise Valves at the entrance between the left Auricle and Ventricle named Valvulae Mitrales fastened by the final Cordae Tendineaes on the left side of the Heart. The left Ventricle is larger and a stronger & much thicker muscular bag than the right Ventricle, its internal part tougher and the Carnae Columnae bigger. As the entrance out of the left Ventricle into the Aorta are likewise three Semilunar Valves. The Heart is contained in a strong Membranous bag called Pericardium the internal part of which bag is very smooth and lubricated with a juice that continually transudes through the same H. Same Dr. Plott in his History of Staffordshire attests of his own knowledge the case of one Mary Eagle who drew two quarts of milk from her breasts every day besides what her child sucked and that she could make two pounds of butter every week ever since she was brought to bed which was above five months when the Dr. saw her. Borellus in his Hist: & Absence: physioc-med: related an instance of the like native in one Mary Caron a Taylor’s wife of Bologna who afforded milk enough for two children & made Butter besides Biog Dictionary Led: Esq: Lect. 43d: Of the Diaphragm The Diaphragm is a large Muscle between the Thorax and Abdomen, the muscular fibres of which arise from the internal part of all the ribs below the sternum, and from the lower end of the sternum, these fibres terminate in a tendinous expansion which is nearly in the middle of the Diaphragm, and which is of an oblong figure coming very nigh the sternum upon which part the Apex of the Heart lies, and from thence turning down towards the Angle of the Ribs and is called the oval tendon of the Diaphragm the lower part of the Diaphragm is likewise muscular and on each side of the Vertebra are muscular Fibres sent Sent down some distance called the Crura of the Diaphragm, these terminate near the Origin of the Psoas muscles which arise at the internal part of the Vertebra of the Loins and pass out of the Abdomen at the Inguen to be inserted into the Os Femoris. it is by making way through these muscles that Abscesses of the Loins sometimes fall down to the Thigh and are opened and discharge their contents there. There a three Apertures thro' the Diaphragm, one of the right side of the Vertebra through which the Vena Cava goes, a second contiguous to the Vertebra inclining a little to the left thro' wc. goes the Aorta, a third over the Aorta & exactly over the Vertebrae through wc. the Oesophagus goes. Of Lecture 44th: Of Respiration Respiration is an alternate dilatation and contraction of the Thorax the former performed by Inspiration and the latter by Expiration. The parts subservient to Respiration are divided into Active and Passive The active parts are the Ribs, Sternum, Heart &c: acting upon the the passive which are the Lungs themselves. The dilatation of the Thorax happens both in length and diameter; in length by means of the Lungs pressing upon the Diaphragm and thereby rendering its convexity more plane, the diameter is increased by the motion of the intercostal muscles &c: Thus the capacity Capacity of the Thorax is increased and as there is no vacuum between the Lungs and ribs allowed of in a natural state, the capacity of the Lungs will also be increased and there will be a vacuity in the Lungs wc. nature not admitting of and by the pressure of the Atmosphere rushing through the Aspera Arteria they are soon filled with Air making Inspiration. The fresh Air that is drawn in by Inspiration stretching the Bronchiae and stimulating the same cause them to contract and expel the Air making Expiration, some Authors imagine these are small Muscles between Between the cartilaginous Rings of the Bronchiae which they call Musculi Mesenchrondroeci serving to contract the the same in Expiration. The uses of Respiration are four, 1st For the circulation of the Blood, thus in Inspiration the Lungs are distended and the fine contorsions of the Arteries are are elongated so as to allow, blood to pass through them whereas in a collapsed state the blood cannot pass through them. in Expiration the Lungs collapsing push the Blood through the Veins into the left Auricle of the Heart. 2d. For sanguification by communicating the Blood making it more florid & denser 3. For cooling the blood 4th. For Vocification, exclusion of [illegible] &c: Of the Peritoneum This membrane is similar to the pleura, being smooth on one side & connected by cellular membrane on the other; it is reflected from the contained path to the containing. It makes a compleat bag 1st: covering the viscera by intimate connection, & then covering the abdominal muscles loosely on the inside. The peritoneum has been considered as a double membrane true or false, the last is no more than cellular membrane wch. connects the peritoneum to the external parts. We may conceive that all the viscera are behind or without the peritoneum, wch. running up on one side of a viscus is reflected back on another so as to form an almost compleat cover to each viscus separately, so that by a very nice dissection the peritoneum may be taken out in a compleat bladder having no perforation at all, leaving all the viscera undisturbed. Lecture 45th: Of the Stomach The stomach is a large muscular bag situate Obliquely from the Left Hypochondrium to the Epigastrium and serves for the reception of our food & digestion of the same, it has an upper & lower curvature called the lesser and greater curvatures of the stomach. There are two Orifices to the stomach; the superior one called the Cardia which enters it from the Oesophagus don't open at the fundus of the same but obliquely, at the side an inch or more from the end. Towards the inferior end the stomach grows smaller & turns up opening into the Duodenum by an Orifice called the Pylorus where there is J The Nerves of the stomach come from the par vagum. Is a partial kind of a valve which does not prevent the regurgitation of fluids into the stomach being only a thickness of the internal coat of the stomach. The stomach is furnished with Nerves and blood vessels. x Some Anatomists say there are small glands in the stomach, but if so they are not easily discovered, there is however a fluid discharged into the stomach from the extremities of the Arteries called the Gastric lymph from the gastros the Greek name for the stomach, there is likewise Lymphatics which absorb the redundant fluids & carrys it into the blood. The coats of the Stomach are three 1st. coming from the peritoneum and is called called the Peritoneal Coat. 2d. Muscular being composed of thin muscular fibres running longitudinal and transversely by which the capacity of the stomach is decreased the readier, to expel its contents. & 3d: Villous or internal Coat which is thin. Of the Intestines The first Intestine next the stomach is the Duodenum beginning at the Pylorus and ascending two or three Inches, has then two or three inflections pulsing down & across the Vertebrae — being all the way tied fast by a duplicature of the Peritoneum to the back, having no mesentery. The Ductus Choledocus & ductus Pancreaticus both enter the Duodenum several Several inches from the Pylorus, not both by one Orifice but by two very near together, next the Duodenum is the Jejunum, & then the Ilium which is the last of the small instestines. The coats of the Intestines are three the same as the Stomach, and in the small intestines are anular duplicatures of the internal Villous coat forming what is called Valvulae Coniventes which serve for two purposes, first to make the passage rough & prevent the Faeces, from passing on too fast and secondly to give more capacious origin. to the Lacteals The Ilium enters the Caecum not at the end but about an Inch there from obliquely the blind end only being Being called Caecum, where there is an appendage called Apendicula Vermiformis. At the entrance of the Ilium into the great Intestines, there is a Valve formed by the inner coat of the Colon & called Valvula Colli which in a sound state entirely prevents the regurgitation of the Faeces or any fluids passing, injected per Anum. The Colon runs up the right side then along under the stomach and down the left side, surrounding all the Abdomen, hence Clysters beside discharging the Faeces serve the purpose of a fomentation to the contents of the Abdomen. The Intestines are furnished with blood vessels from the two mesenteries except except the Rectum which receives its from the Hemorrhoidals. The Mesentery is a double membrane formed by a duplicature of the Peritoneum serving to connect the Intestines. & through which which the blood vessels go to be distributed to the Intestines, through it likewise goes the Lacteals which are fine Lymphatic or absorbent vessels arising from the villous coat of the Intestines and passing through the mesentery, they terminate in the Receptaculum Chyli, to be described hereafter, there is also a great number of Glands in the Mesentery through which the Chyle passes, and by which it is supposed to receive some alteration. These glands are very small. Lect. 46th Of the Lacteals & Thoracic Duct The Lacteals are an innumerable number of small vessels arising as before said from the villous coat of the Intestines & running through the mesentery in the duplicature of the same and through many fine glands and terminate in the Thoracic Duct serving to convey the Chyle The Thoracic Duct is a small canal running up the Vertebra of the Spine between the Aorta & Vena Azygos and under the Vena Cava until it gets above the Heart then it turns a little to the left and ascending empties itself in to the subclavian Vein. The lowest end of this Duct has been called Receptaculum Chyli but improperly as its no larger than the rest of the Duct neither do all the Lacteals enter there, but some higher Of Digestion Digestion is that change of the Aliments whereby they are filled for the nourishments of the body, this is different from the different juices mixed therewith and in the different parts of the body. The first change that happens to the Aliments is in the mouth by means of Mastication and mixing with the Saliva by which it is somewhat dissolved and fitted for more easy Deglutition Saliva is a clear mucous transparent fluid secreted by the Glands of the Mouth in the great plenty, and is of great use in digestion. After the Aliments is sufficiently masticated & mixed with the Saliva they are by the Tongue pressing against the roof of the Mouth forced into the Pharynx Pharynx and from thence through the Oesophagus into the Stomach. The Muscles employed in this act of deglutition are very many, serving chiefly to pull up the Oesophagus and to press the food down through the same, and we may very well conceive of the act of Deglutition by that of drawing a stocking on the Leg, part of the muscles drawing up the Oesophagus as we draw up a stocking upon the leg, and the rest pushing down its contents as we push down our leg into a stocking. The manner in which our food is digested in the stomach was by some of the Antients reckoned to proceed from heat K Heat, others reckoned it was performed by means of trituration, and others again from the different juices there mixed imagined it was performed by Fermentation, but modern Physiologists from many observations, think it is performed by all three jointly viz: Heat, friction and Fermentation. After the Aliments are sufficiently digested in the stomach, by the contraction thereof which is the beginning of the peristaltic motion of the Intestines, they are forced through the Pylorus into the Duodenum, where it continues some time and receives another change by having the Bile and pancreatic juices mixed therewith. The The Bile is an oily bitter, and attenuating substance endued also with a saponaceous virtue it will incorporate with Oils and when so mixed they are both soluble in water, it unites with salt forming a green color. by which it appears that the Bile is of great— use in attenuating the viscid part of the Aliments, and stimulating the— Intestines, the latter we are assured— of by this that Bile secreted and— discharged into the Intestines in too great a quantity causes a Diarrehea, and in a Jaundice where the Bile returns into the Blood and is not sent into the Intestines a Costiveness happens with while stools, and Boerhaave says Says the Gall of Animals is of use in this case to supply the want of Gall DeGraaf collected great quantities of the Pancreatic juice from Animals which he says is subacid it is reckoned to be somewhat of the nature of the Saliva, some reckoned it serves to sheath the Acrimony of the Bile but this in a natural state is not too Aerid These two fluids being mixed with the Aliments in the Duodenum the fluid and nutritious particles of the same are absorbed by the Lacteal vessels and by them carried into the Thoracic Duct to be conveyed into the Blood. These Lacteals are in all the intestines, but in the small ones in the Greatest Greatest plenty, That there are also Lacteals in the Colon seems evident 1st. From the rout the colon makes round the Abdomen, for if that is not for absorbing the particles that may chance to be not taken up by the vessels in the small Intestines why did it not go out strait like the Rectum and immediately terminate in Ans? 2. From persons being known to have lived a long time by Glysters, not being able to get any thing thro' the Oesophasgus, & it is known that they cannot pass by the Valve of the Colon. The contents of the Intestines are carried along by the Peristaltic motion thereof thereof. Vomiting is an inversion of the peristaltic motion and is performed by means of a deep inspiration which presses the Diaphragm against the stomach & a convulsive contraction of the stomach by which its contents are thrown up hence we learn that Emetics are good in Fluxes by inverting the peristaltic motion they stop the same. Of the Bile Bile is secreted in the Liver. It is 8 times as viscid as water. More subject to concrete than any other humour in the body. Its specific gravity to water is as 010 to 795. In a such quadrupeds & in the human species the bile is very bitter, but most so in carnivorous animals. Recent bile easily mixess with water. It mixes with oil by triture. Mixed with water it partakes of the property of Soap, dissolves oil so that it will mix with water & takes out grease spots. It dissolves resins & mixes with balsams. It dissolves Myrrh Bdellium & Wax like the yolk of an Egg, & is supposed to dissolve the Blood when mixed with it as in a Jaundice. The Ductus Choledochus may may be compressed & stopped by the Duodenum being distended with flatus. Eating Mushrooms has been known to distend the duodenum greatly & trangulate the ductus choledocus as it were with a ligature. It may also be obstructed by the contractions of the fibres of the intestine from stimuli as happens in the Colica pictonum, biliosa, inflammation of the duodenum, acrid purges, glass of Antimony & poisons. Hither we may refer the Jaundice in Infants which is removed by Rhubarb. Storck has seen the ductus choledochus obstructed with a cheesy coagulum. Hillary says this is frequent in the warm Islands. See Monro Ed: Ess: v. p 247 Baglivi prax: med: Haller tom: 6. p 590 x about 4 fingers breadth below the pylorus. Lect. 47th Of the Liver The Liver is a large Viscus situated immediately under the diaphragm mostly in the right Hypochondrium extending over the Stomach into the Epigastrium it is convex above and concave below suspended by three Ligaments one above to the Diaphragm one broad on the upper part of the round ligament from the Umbilicus which was the Umbilical Vessel in a foetus state. There are several fissures in the Liver 1st. Divide the great lobe from the lesser one. 2d. divides the Lobulee spigeli & the third where the Hepatic Vessels enter; The Vesica Fellis lies in a depness in between the two lobes of the Liver from where goes a duct remarkably contorted to appearance about two inches when it joins the hepatic duct, both of them united form the Ductus comunis Cholidochus which terminates in the Duodenum. x The Coat of the Liver comes from the L x sometimes called Tunica Glissoniana *The hepatic Artery divides a little before it enters the Liver one branch going to one lobe & the other to the other Lobe; it serves to nourish the liver & is said to secrete a small part of the Bile, some few of its evanescent frame has terminating in the pori biliarii as is proved by injections. The Peritoneum x beside which some Authors describe another coat wc. is scarce to be seen, The Gall Bladder has three coats 1st. from the Peritoneum, 2d: Muscular & The 3d. Villous, appearing like a honey comb inside. The Liver is furnished with Veins Arteries & Nerves. The Blood Vessels are the Hepatic * Artery & Veins & the Vena Porta. The Vena Porta is like an Artery first in its Office & 2dly. in the thickness of its coats; it arises from all the Viscera of the Abdomen terminating in the Liver and is supposed to carry the blood for the secretion of the bile, 1st. From the longness thereof & the smallness of the hepatic Artery. 2dly: By injections passing from it into the biliary Duets &c: It is certain however that the blood being carried into the Liver, part of it is converted x The general opinion of the ancient Anatomists was that the bile was conveyed into the Gall Bladder by little ducts running from the liver immediately into the bladder which they called ducti hepaticistics. Pechlin was the first who denied the existence of these ducts in the human body, then Ruysch, Cowper, Bidlow, Berger, Morgagni, Heister, Ludwig, Carsons, Lieutaud, Ceyer, & Cheselden. who says if a ligature be applied round the cystic duct, or if it be obstructed the gall bladder does not become turgid. Bohnius emptied the gall bladder of bile then tied a ligature round the cystic duct & upon examining the same several days afterwards found no bile in the cyst itself but the part of the duct between the ligature & liver was greatly distended. Bianchus & Haller have done the same. This clearly proves that there is no communication between the Liver & Gall bladder but by the cystic duct. What was supposed to be Hepatocystic ducts is demonstrated to be only blood vessels by Ruysch, Guntz, Haller Morgagni & others. converted into Bile & carried by the pori Biliarii which all meeting together form the hepatic duct though the hepatic duct to the cystic then regurgitates into the Gall Bladder; that the Bile regurgitates thus x into the reservoir is proved 1st. by there being no other passage though some supposed there was by little ducts wc. they called cysto hepatic ducts, but there is no such is evident from the injections not passing through that way into the Cyst, & in a Viper the Gall Bladder is vitiate some distance from the Liver. Horses & Deer have no Gall Bladder. That the Bile goes through the hepatic Cystic Ducts into the Gall Bladder is proved 2dly: by blowing into the hepatic duct the wind passes free into the cystic than through the ductus cholodochus. The remainder of the Blood is received by the Veins & carried back to the Heart Diseases x more frequently if not always the Jaundice arises from an obstruction of the Ductus communis Cholidocus An obstruction of the cystic duct alone will not occasion a Jaundice. Diseases of the Liver are: 1st. Hydatides these are of two sorts the first tumors composed of several lesser cysts filled with a gelatinous matter, the other a kind of vascular Cysts, the fluid circulating through it. 2d. Inflammation this is best relieved by plentiful bleeding warm relaxing and stimulating applications &c: It sometimes suppurates & even grows cancerous. 3d Scirrhi like other Glandular parts 4th. It gives origin to the Jaundice wc. proceeds from an obstruction in the Cystic x duct by wc. means the Bile is prevented from going into the Gall bladder and therefore returns into the Liver where it is absorbed by the Veins or lymphatic Vessels & carried into the blood & by that means tinges the shin, the cystic duct may be stopped by concretions tumors compressing the The same or more commonly by means of a stone lodged therein: a stone or concretion is best removed by Vomits which agitating the parts serves to remove it or by friction stimulating the same. Some have imagined that a Jaundice proceeds from a scirrhus Liver, but this is proved to not be the cause as no Jaundice can be unless the bile is absorbed after it is perfectly made Transient Jaundices sometimes happens to Children from a spasm of the Duodenum from acidities or otherwise hinders the Bile from passing therein & which is relieved as soon as the spasm is removed. Durable Jaundices happen when the Obstruction of the Cistic duct cannot be removed Lect. 40th: Pancreas is a long slender conglomerate Gland situate obliquely under the stomach between the spleen & Duodenum. each little x Haller supposes the pancreas secretes three times as much fluid as the salival Glands. * a costiveness and a pain in the region where this gland is seated is the common symptoms of its being obstructed. little acini or knot supposed to be the extremity of an Artery wound up in a knot and the whole vascular like the liver and all the other Glands of the body. from each acini goes a small excretion Duct which terminates in a larger duct in the middle of the Pancreas & called the pancreatic Duct & through which the pancreatic juice flows into the duodenum, the glands of the pancreas being the same with those that discharge the Saliva are supposed to secrete the same juice and for the same Use. x Diseases of the Pancreas are Inflammation, Cancer, & Schirri, which * are very difficult to be known until past cure they are however removed much in the same same manner as the same Diseases on other parts, Soap is a very good thing in this case which not only seen x This appears very reasonable though it was never taken notice of by any author before Mr. Monro. Is a good resolvent but supplies the place of this juice in digestion. Sometimes a Diarrhea happens in a Salivation and proceeds from a too great a secretion of the pancreatic juice which being the same with that of the saliva is supposed to be effected in the same manner with Mercury & is only to be removed by removing the cause. x Omentum is a fatty double membrane composed or formed by a duplicature of of the Peritoneum it has an appendage between the Liver & stomach called the Omentum minor & may be inflated. Uses of the Omentum are to lubricate & keep the Intestines warm, and it is supposed to supply oily particles to the Bile and also the blood. It is sometimes much distended with Fat and in very lean subjects quite reticular. Spleen Of the Spleen The Spleen is a roundish lobulated Gland situated in the left Hypochondrium it is furnished with blood Vessels and but very few Nerves. The Antients supposed its use was to counterbalance the Liver, others thought it contained a fluid called the Atrabilis, but the moderns mostly think that it is subservient to the Liver, it has been taken out of several animals without any apparent damage and is not therefore a vital viscera. It is subject to very few diseases, scarce ever being inflamed schirrius or cancerated, by reason of the fewness of the nerves, its only subject to a viscidity of its fluid and an enlargement therefrom. Lect. x The arteries generally divide into three branches and the vein into two before they enter the Kidneys. Lect. 49th Of the Kidneys The Kidneys are two Glandular bodies situate between the false ribs & Ilium. the situation of the right Kidney is somewhat lower than that of the left oweing to the Liver being on that side. The blood vessels of the Kidneys are an Artery and a Vein called Renales or Emulgents the right emulgent Artery is longer than the left & the left Vein than the right. These vessels enter at the Pelvis and are distributed through the same. x The external part of the Kidney is called Cortical the thickness of which is irregular and in this the Urine is secreted and emptied into little ducts in the inner part M x the pelvis is an enlargement or expansion of the of the upper part of the ureter where it enters the Kidney or rather where the united urinary Tubes regress out of it. part of the same, which is called the Mamillary part of the Kidneys. The little ducts into which the Urine is secreted are called Tubuli Urinarii and are in number about a dozen, these all unite in the Pelvis x forming the Ureter which is a membranous canal conveying the Urine from the Kidneys to the Vesica Urinaria. The Ureter as it enters the Pelvis of the Kidney divides into three parts one going towards each end and the other through the middle. The coats of the Kidneys are two, the first called Adipose and the second Membranaceous. There is an appendage to the Kidney called Glandula Renales or Gland Glandula Succentriari situate at the top of the Kidneys its particular use not known but supposed to be subservient to the Kidneys. Diseases of the Kidneys are, Inflammation, Diabetes from a too great laxness of the Vessels allowing the red particles of the blood to pass through them, gravel, Scirrhi &c: Lect. 50th: Of the Bladder The Bladder is a membraneous Bag situate in the Pelvis the upper part of which is covered with the Peritoneum but when it is very much distended it protrudes about an Inch above the Pelvis & being there covered with the Peritoneum Peritoneum & in this place is the upper Operation for the Stone performed by making an Incision into the Bladder without cutting the peritoneum the doing which would be of dangerous consequence. The coats of the Bladder are three, 1st: the common coat 2d: muscular and 3d: Villous, the muscular coat at the neck of the Bladder is thick & circular and is called Sphincter. The Ureters enter the Bladder one on each side about an Inch from the neck thereof by a small Orifice obliquely. The situation of the Bladder is between the Rectum & Olsa Pubis in men and between the Uterus & Pubis in women its use is a Reservoir to the Urine Parts of Generation Lect 51st 1st In a Male. These are the spermatic Cord, Testes Scrotum, Vesica Seminales, Prostate Gland, and Penis. The spermatic cord is composed of the spermatic Artery and Vein, Nerves, Lymphatics, & Vas deferens all included in acellular coat and some have supposed a muscular wc. they called Cremaster wc. is not visible except where it passes out of the Abdomen wc. it does in an oblique manner through the rings of the Abdomen, by which the Intestines and Omentum sometimes falls thro' forming an Herniae Inguinalis or Jerotalis along the side of the spermatic Cord The x Caput Gallinaginis The vas deferens empty themselves somewhat like the biliary ducts there being a passage from them immediately into the Urethra, but it commonly regurgitates into the Vesicula Seminales & there kept till used. Vesicula Seminales are two Glands situate under the neck of the Bladder, composed of little cells which communicate with each each other, being reservoirs for the semen, from each of these there goes a small duct which opens into the Urethra at the Caput Galaginis, x where is a large Gland called the Prostate Gland which secretes a fine mucus to defend the Urethra from the acrimony of the Urine. The Scrotum is composed of skin Cellular Membrane &c: next to which has been reckoned a muscle called the Dartos which is not to be discerned discerned, and the first obvious Coat is that wc. surrounds the Testicle much as the Pleura or Peritoneum does the contents within them this is called the Tunica Vaginalis propria Testes, and within that is a coat which adheres to the substance of the Testicle called the Tunica Albuginea, The substance of the Testicle is wholly Glandular, the spermatic Artery entering in at the side of the same and distributed through the same terminating in fine secretory ducts and these again in excretory ducts which uniting into one form the Vas deferens, The Epididymus is an Appendage to the Testicle formed by numerous convolutions of the excretory duct, reckoned 6 times as long as the Spermatic Cord. Lect. 52d: Parts of Generation in Females. These are either external or internal, the external are the Mons Veneris on which hair grows at a certain age Labia or External Lips of the Orifice at the upper part of wc. is a small body called the Clitoris under which in a small groove is the Iter ad Urinam thro' which the urine passes & into which the Catheter must be introduced in a suppression of Urine, & we should be well acquainted with this Orifice as the modesty of women often denies us a sight of the part, so that we must introduce the Catheter by feeling, at the lower part where the Labia unite is formed a Fraenum or Fushet or Foushette. x Iter externum ad Uterum Nymphae are two spongy bodies within the Labia within these in Virgins is a circular membrane called Hymen within these is the Iter externum ad Uterum x Vagina is a membranous substance furnished with rugae by wc. the Penis is more titillated in Coitus, there is likewise many small glands in the Vagina wc. secrete a liquor to lubricate the same and during the Venereal orgasm whether real or imaginary there is sometimes so much mucus secreted by these glands that it has been discharged, in great quantities so as to wet all the external parts, this by some is reckoned the Female semen. At the bottom of the Vagina is the Iter internum ad Uterum, the Os Uteri or Os Tincae. N Between x or young Puppy Between the Fushet and Anus, there is a seam called Perinaeum, this in difficult deliveries is sometimes lacerated by the largeness of the Foetus & it is necessary to prevent this accident for to support the Perinaeum with the hand while the Foetus advances Uterus is a small body situate obliquely between the Bladder & Rectum its coats size near half an Inch thick & its internal cavity very small; the Neck of the Uterus is full of rugae wc. serve to allow the same to dilate for the expulsion of the Foetus. The Os Tincae resembles the mouth of a Tench x situate at the bottom of the Vagina tho' not a continuation thereof the Vagina being inserted x An demande si le corps de la matrice etant renverse, & ayant tente inutiliment va induction, elle montroit quilque disposition a ve gangrener, e il conviendroit pour lors de l’eactirper, apris avoir porte une ligature le plus haut qu’il veroit possible. En parsil cas on ne devroit point balancer de faire cette operation pour empecker que la gangrene faisant du progres du cote des parties interieures, elle ne causat la mort a la malade. L'extirpation de la matrice, quoique rare, never sit point en cette occasion une operation temeraire, son succes etant prour a par plusieurs observations Verdeer's Anal: v: 22 p 66 Rousset, dans son Traite de Partes Caesares, dit qu'une femme a la suite de pluesieurs accouchemens laborieux, eut une precipitation de matrice qui ne pouvant etre inserted round the Os Tincae. From the Fundus of the Uterus there goes off nearly transversely on each side, a tube called the Fallopian Tubes lying loose & growing larger toward the further end wc. is fimbricated. The Uterus is suspended by the ligament lata & rotunda x Ovaria are two glandular bodies situate on each side of the Uterus inclosed in cellular membrane in each of these Ovaria are near 20 small Ova Of Generation This is perfomed per Coitus by the Male’s introducing his Penis into the Vagina, & perhaps into the Os Uteri tho' this is denied by some at which time the parts grow turgid by the venereal Orgasm the Os Tincae opens & receives the male Semen in which are Anamalcules, immediately attended. reduite, se gangrena, & tomba d’elle-meme. La femme ne daigna pas garder le lit, & elle Jouit d’une parfaite vante’ pendant trois ans, au bout desquels, etant morte d'uno fievre continue, louverture de fon corps fid voir que c’ etoit veritablement le corps de la matrice, qui par pourriture s’etoit s’epare de lui-meme Ibidem p168. afterwards the Os Tinca closes During the Orgasm the fallopian Tubes grow erect & the Timbria seize the Ovaria at wc. time some one or more of the Animalcule ascend through the Fallopian Tubes & enter the first ripe Ovum wc. has now burst the cellular membrane by its turgidity, then the Ovum is disengaged & carried by the Fallopian Tube into the Uterus, and the place where the Ovum was in the Ovarium is soon after filled up by a yellowish substance called Corpus Luteum, this I proved by opening a Bitch in the Hornes of the Uterus were 7 whelps in one three & the other four & in the Ovaria were the same number of Corpora Lutea, by alike experiment upon a Bitch opened while the Dog was fastened thereto, for dogs have no Vesicula Feminalis are obliged to remain fastened to the Bitch a a long time while the Semen is excreted and carried from the Testes by the Vas deferens into the Uterus I found that the semen was ejected immediately into the Uterus. Though the preceeding Hypothesis seems incredible and almost impossible, yet it answers all the Phenomena of Generation the best of any system yet advanced: however the subject is extremely intricate & no doubt is one of the Arcana natura which the omniscient Jehovah of his infinite goodness sees fit to hide from us. Lect: 53d. Of the Foetus its Nutrition &c. The Ovum of the female wc. is foecundated in the preceeding manner by the semen Masculinum is supposed to contact also the membranes that envelop the foetus with the Placenta, Umbilical Chord &c: The Ovum lies in the Uterus 9 months, but for the first two or three months the Placenta does not adhere to the Uterus The Chorionis the external coat of the Foetus it is a thick spongy membrane. The Amnios is within the Chorion it is very thin and smooth, between these two membranes some have described another called Alantois wch. includes the Urine of the foetus carried there from ye. bladder by the Urachus, this is found in some brutes but cannot be discerned in the human species The Placenta is made up of a congress of vessels. How does the Placenta adhere to the Uterus? How is the Foetus nourished? is it by the Mouth; the Umbilical Vein, or by both together? Does red blood go immediately from the uterine Vessels of the As first this want of Navel String, 2d: a diminution of the the Liquor Amnii, 3d. Mucus being found in the mouth & stomach & meconium &c: # 1st. A want of mouth or any passage into the chylopoetic organs, 2d a corruption of the Liquor Amnii 3d. That the liquor Amnii is an exudation from the foetus & consequently not fit for its nourishment &c: the mother through the Placenta to the Foetus & vice versa? from whence comes the Liqour of the Amnios? these are question, that have been differently solved by physiologists. Some have imagined that the placenta adheres to the Uterus by its vessels inosculating with those of the Uterus, others imagine there is no continuation of vessels by inosculation from the placenta to the Uterus, but that the placenta adheres thereto by a kind of cement; for (say they) if it adhered otherwise there must be a laceration (& consequently an inflammation & suppuration) wc. does not happen when it is bro.' away. As to the Nourishment of the foetus many have imagined that it rec'd. nourishment by the mouth & bring many arguments to prove it*, on the contrary others deny that the Foetus receives any nourishment by the mouth but wholly by the umbilical Chord - this is the most viewed Opinion, but for a particular acc't. of the Nutrition of the Foetus in Utero side Med: Essays of Edinburgh and Dr. Shippen’s Thesis for the connection of the Placenta to the Uterus A It was the rec'd. Opinion till of late by all who allowed the foetus to be nourished by the umbilical Chord that red blood was immediately conveyed from the mother to the foetus; Their arguments for it are 1st. that if the mother bleeds to death the Foetus will be deprived of blood also. 2d. Injections pass from the mother to the Foetus. 3d. that hemorrhages happen upon a separation of the placenta from the uterus. 4th that the umbilical Chord will bleed a great quantity when cut &c: but the most modern doctrine that now prevails & wc. answers all the phenomena best is that red blood does not pass immediately from the mother to the Foetus, for before the placenta adheres to the Uterus it certainly cannot, & then it must be nourished by absorption of the Placentine vessels as well before as after its adhersion to the Uterus; we have said before that the placenta does not adhere to the Uterus by inosculation of the Vessels, but by a slight cementation, thence we suppose that the the small ends of the placentine Vessels open into the mouths of the uterine ones, and as the mouths of the uterine Vessels are so large near the time of delivery as to admit a goose quill whereas the mouths of the placentine Vessels are so small as not to admit red blood its very probable there are many of the placentine vessels open into one of those of the uterus. These small placentine vasculae are part of them supposed to absorb the chylous & ferrous nutritious part of the blood in the uterine vessels which the placenta forms into red blood before it is conveyed to the Foetus; The manner how the placenta acts in forming this nutritious fluid into blood is unknown, but it is supposed to perform the office of Lungs in that particular. The placentine vessels having absorbed the nutritious particles of the mother’s blood and and the placenta formed it into red blood it is conveyed by the umbilical Vein into the Foetus, for its increase & nourishment, while the superfluous & unnutritious part is reconveyed by the umbilical Arteries into the placenta & is absorbed by the uterine Vessels and mixed with the blood of the mother; thus instead of a reciprocal circulation between the Foetus & Mother which was formerly Supposed, and is still by some, there is only a secretion of the fluids which pass from one to the other. The Arguments brought to Support this new doctrine are, 1st: That upon the mother’s bleeding to death, the Foetus will not be deprived of any of its blood this Dr. Shippen proved by an experiment he made in Edinburgh before Alexander Monro jun'r he bled a Bitch to death then opened her and took out her whelps which appeared to have lost not one drop of blood blood. 2d. That the umbilical Cord when cut will not bleed but very little, no more than the blood contained in the Placenta, this most Midwives know & it is mentioned by Smellie: but 3d. Lastly the greatest argument of all is that Injections cannot be made to pass from the placenta into the Vessels of the uterus nor vice versa tho' it has been repeatedly tried by the greatest Anatomists notwithstanding what has been said by some to the contrary. A Course of Bandages Bandages are very necessary to confine dressings upon any external part of the body, injured either by accident or by a necessary Operation. Lect: 54th: Bandages of the Head. 1st: Handkerchief doubled & made 3 square put round the head & tied behind 2d: Grand Covre Chef a large square handkerchief doubled to ab.t 2/3 the way & laid on the head the single part so as to reach the Nose, the double part the forehead, wc. double part being uppermost must be fastened under the Chin, the other then turned up & tied behind in the nape of Neck 3d: Poormans Bandage of Galen a piece of linen cut into 6 tails & laid on the top of the head, the middle tails fastened fastened under the Chin the hind ones before & the fore ones at last behind. 4th: Capaline a long doubleheaded bandage 4 or 5 fingers breadth wide to put round the head 5th: Uniting Bandage double headed & like the former with a slit near the middle to be applied to a wound of the forehead. 6th: Scapha for bleeding in the frontal vein going several times round the head at last the first end turned over & tied behind 7th: Kiaster double headed for bleeding in the Temporal Artery going several times round the head then twisted round to a hard knot over the Orifice & then part one end over the crown the other under the Chin and fastened. 8&9 Monos- & Bi-Ocular double headed the first covering one Eye the last both Eyes Lect. Lecture 55th: 10 Accipiter a T Bandage for the Nose going round & tail tied over the head. 11 A four tailed sling bandage for the upper Lip. 12 A four tailed sling bandage for the Chin the under half being the broadest. 13 Capistrum double headed bandage passing from under the Chin to top of the head then to neck & round to the Chin &c: 14. Divisive along double headed rowler to keep up the head. Bandages of the Trunk 15 Spica double headed for the shoulder 16 Star Bandage for a fracture of the Clavicle a single headed rowler & if necessary the Capaline may be applied with it for greater safety. 17 17 For the Thorax the Jenriette or Napkin & Scapulier the first going round the body the latter slit going over the head & fastened thereto. 18 Suspensor of Heliodorus for a diseased Breast a X bandage 19 For Paracentesis a broad flannel roller to go round & compress the Abdomen. Lecture 56th: 20 Spica Inguinis double headed for any disorder in the inguen. 21 T Bandage or Suspensor Scroti beside wc. there are several others of less note to these parts particularly the Truss Bandages of the Extremities 22 Deloer for the Wrist 23 Spica Pollicis for the thumb. 24 Gauntlet ~ } for the fingers 25 Denigantlet 26 26 Eight tailed bandage for a broken Patella &c: 27 For a simple Fracture Thypodesmus going round under the splints a single headed roler & Epidesmus going over the splints one roler very long may serve for both. 28 For a compound Fracture where there is a Wound &c: the 18 tailed bandage together with splints Tape &c: and lastly Junchs, Box, or Cradle &c: if it is one of the Legs. A Course of Operations Lecture 57th:~ Of Sutures There has been many sutures invented most of which are out of use. We ought to observe that a wound made longitudinally in the direction of the ~ Fibres requires no sutures be it ever so great, for by means of a bandage the sides of the Wound is easily brought together without suture. But a wound made obliquely or transversely requires a suture as no Bandage can be made to keep the wound together. The intention of Sutures is to bring the likes of a fresh wound in apposition, that the vessels may inosculate & heal by the first intention, the chief sutures are The Glovers stitch, The interrupted suture, The quilled suture, & the Gastroraphy, The Glovers stitch is performed with a strait needle & waxed thread single, turned over and over. The interrupted Suture is made with a crooked needle & single waxed thread the lips of the wound being brought together first make a stitch in the middle the Rule for which is to begin as far from the edge of the wound as the wound is deep making the needle come out at the bottom of the wound & continued thro' on the contrary side then tied not over the wound but on one side, then make two other stitches near each end wc. is mostly sufficient. Quilled Suture is made with a crooked needle as before with a double cord & tied at the end with a quill on each side the Wound. The The Gastroraphy is performed when the parietes of the Abdomen & Intestines are cut. The intestine is to be saved up with the Glovers stitch leaving a piece of the thread at each end to lie out of the wound of the Abdomen, then the Parietes is to be stitched with the interrupted Suture in a particular manner viz: on each end of a waxed cord must be put a crooked Needle, then take one needle & from within the wound push it out then take the other needle & do the same on the other side of the wound, bringing them together & tying the same, do so until you have as many stitches as you think is necessary Of Trepaning When it is necessary to perform this Operation we should consider first the places where the Trepan may be applied; there are 3 places where it is improper to apply it viz: to the Sagital Suture, the frontal Sinuses, & the Os Accipitis. In Operating, an Incision must be made of a good length through the scalp, the same opened & the Cranium scraped, than having fixed upon the place apply first the perforator & after that the Trepan secundum Artem. Of Fistula Lacrymalis This operation is performed when the ductus as Nasum is stopped & has formed in the Lacrymal Sac &c: Sometimes compression alone will cure this disease but when the Operation is necessary its performed by making an incision over the Sac at the bottom of the Orbit & half the length of the same, into the Sac & cleaning out out the matter & if necessary making an Aperture through the Os Unguis with a strong Probe or a Trocar into the Nose. Of the Polypus of the Nose This is an excrescence growing in the Nose in the Schneiderian Membrane, has different degrees of firmness, in a recent state it is very tender but by degrees grows harder until it gets to a great firmness; the best time for extracting it is when its so hard as not to break easily with the Forceps but not so hard as to adhere to the Schneiderian membrane too strongly. Its extracted by taking hold of it with the polypus Forceps & working it to one side and the other backwards & forwards &c: until it is loosened. Extirpating the Tonsils. This is best done by Ligature for fear of an Hamorrhage if the Tonsils are largest at the apex its an easy matter with proper Instruments to pass the Ligature round its basis & make it tight, but, it often happens that the Basis is largest in this case a ligature put round woud slip off therefore with a proper needle it must be run through the middle of the Tonsils & tied on each side cum node Chirurgica &c: Of Amputation Amputation is sometimes necessary but not near so often as has been thought; all agree that it is necessary in a Mortification, but then it must not be performed until the mortification is stopped & even new flesh begins to granulate. In Amputating the Leg we must stand between the legs that the saw may take the Fibula before the Tibia is quite cut off. we We first apply the Tourniquet to the thigh to stop the blood, then with a strait knife wc. is the best we make a circular incision with two cuts round the leg or thigh through the skin cellular membrane & fat about an Inch below where we intend to cut off the Bone, then an Assistant must pull up the skin as high as possible, after wc. the Operator must make a second Incision through the muscles to the bone then if it’s the leg or forearm the double edged scalpel must be run between the bones to cut the interosseous Ligament & Muscles, lastly the bone itself must be cut off with the saw. & then the Arteries taken up &c: The Fingers are Amputated contrary to all other parts at the Joins by cutting the flesh as before then stretching it up & with the scalpel beginning on the side take off the Joint. Of Empiema This is an operation for letting Pus Water or Blood out of the cavity of the Thorax, oftenest Pus, wc. comes from an inflammation & Suppuration, when this is in but small quantities, the Lungs by then great power of Absorption often carries it off by Expectoration as we see in Pleurisies; but when in great quantities the operation must be performed very carefully for fear of hurting the Lungs between the 6 & 7 or 7 & 8 Ribs with a common scalpel. Of Bubonocele This is the dangerousest operation in Surgery, & not to be performed but when absolutely necessary; when so it is done by making a long incision from above the rings of the abdominal Muscles almost to the bottom of the scrotum carefully in to the Intestine thro' the Peritoneum or Herniary Sac then dilate the passage by incision & carefully reduce the Intestine. Of Couching This Operation is performed for the removal of a Cataract or opacity of the crystaline Lens; there are two ways of doing it, the old way of depressing the Lens with a needle to the bottom of the Eye into the vitreous humor wc. is done by running the needle abt. 1/10 of an Inch below the Cornea into the posterior Chamber behind the Iris & depressing the Lens. The other method, wc. is the new way, much in vogue at present, & I think the best is to cut the Cornea & extract the the crystalline Lens. In the Old way the Lens is very apt to use after it has been depressed wc. makes this new way preferable; it is performed by a small knife with but one Edge wc. is to enter near the place where the Needle enters & pushed thro' into the anterior chamber above the Iris (taking care not to cut it) and out on the other side cutting half or better of the Cornea, then with the point of the knife cut the capsulae of the Lens & its easily pressed out. Of Lithotomy This Operation is performed for extracting a stone out of the Vesica Urinariae; there has been several methods invented to perform this operation but the Lateral Operation or that invented by Irene Jaques is the best & universally in use. We are not to operate until we are certain there is a stone in the Bladder & we can feel it by sounding & all the other Surgeons present. In Operating we first tye the patient on a Table of a sufficient height lying on his back by making a noose with a garter round the Wrist then making him take hold of the bottom of his foot with his hand putting the Garter round his Instep & hand in form of 8 a sufficient number of times, with an assistant to hold each knee then introduce the Staff into the bladder, letting a careful assistant hold the same bending the top a little towards the right Groin is as that the bend of the same may turn a little to the left then then the Operator setting down right before the Patient must with a sharp scalpel make an incision immediately upon the staff from the Base of the scrotum to beyond the anus abt. an Inch to the left of Cerines through the skin & fat, (this should be made thus large that we may get at any Artery if necessary) then make the incision shorter down to the staff when we feel the staff bare we must take the Gorget put the point of it into the Groove of the staff then take hold of the staff from your assistant & turn it over while you slip the Gorget along the groove into the bladder, then take out the staff, & introduce the Forceps upon the groove of the Gorget, when they are in the Bladder pull out the Gorget & gently feel for the stone, when you find it take care to get good hold of, it not being in too big a hurry; when you have it fast extract it. If the stone breaks take out what you can with the Forceps & the rest with a scoop. The wound must be drest gently wth. dry Lint. Med. Hist. MS. B 158 Of Tapping Of Injections The ancients used to employ only Ink for Injections (which answered the end but very poorly) until the time of Ruysch who made his injections of wax, some of wc. have since been improved; his method of Injection was as follows viz. He first laid open the hypogastrium & made two incisions about an Inch long into the Aorta & Vena Cava, then put the Subject in cold water several days pressing out the blood frequently. Next he put them in warm water several days more & put two tubes in the Artery one upwards & one downwards & fastened them tightly. His injection was only simple Suet calomel with Cinnabar in cold weather & in the Summer time he added a little white wax & injected it gently when warm into the vessels, then put the Subject into cold water till the injection was cold, then dried the preparation carefully or preserved it in spirits of wine Injections used by the modern are the follg: Corroding Injection of Dr. Nicholls Rx Wax 4 ounces Resin 3 ounces when melted add Turpentine Varnish 3 ounces Dr. Hunter's Corroding Injections Rx Wax 3 ounces Resin 3 ounces when melted add Venice Turpentine 11 ounces Another Rx Wax 4 ounces Resin 3 ounces when melted add Oil of Turpentine 2 ounces Another Rx Wax 4 ounces Resin 8 ounces or 10 ounces Tallow 3 ounces melt them together The Injection is known to be of a proper consistence by dropping some of it when melted in water & when thoroughly cold forming it into the shape of the Vessels if upon Landing it breaks it is too hard if it bends easily it is too soft & must be mended. Those Injections which have Turpentine Varnish, Venice Turpentine or Oil of Turpentine in them must be tried as above every time they are heated because in heating they loose of their volatile oil Of the Colours To the foregoing Injections such a quantity of colouring matter must be added as will give them a bright colour which must be determind by the Eye Colours generally used are Vermillion Kings Yellow, Blue Verditer & Flake White. Other colours may be used. They are generally to be mixed with the Injections when they are melted; but there are some objections to this rule in some of the colours particularly the blue Verditer & in some measure the Flake White for Navy both ferment when mixed with the foregoing Injections; to prevent which it is necessary to melt some of the Ingredients alone & add the colour to it before the other Ingredients are added. The following Experiments will particularize these Exceptions 1 Blue Verditer with Tallow alone causes no Fermentation 2 Blue Verditer with wax alone don’t Ferment 3d. Blue Verditer with Resin alone does ferment, therefore mix the blue Verditer with the Tallow or Wax alone or together & afterwards add the Resin which causes a small froathing If Turpentine Varnish, Venice Turpentine or Oil of Turpentine be used mix your colour first with the melted wax & then add either of these Ingredients with the Resin These observations are equally true of the Flake White When we make a white Injection instead of yellow Wax we use white. It would seem that we have not yet any Green Colour, but as blue & yellow make a Green the blue Verditer added to the yellow wax or Resin gives us a fine green Dr: Nicholls fine Injection Rx Hard Brown Varnish & hard White Varnish a 5 ounces Turpentine Varnish 2 ounces add the Colour & shake the Vial first putting some shot therein to make them mix. Either of the hard Varnishes will do as well as both adding the same proportion of Turpentine Varnish viz 1 to 5 Another Rx Hard Brown Varnish & hard White do. a 8 ounces Venice Turpentine 2 1/2 ounces mix these as the former If we neglect being nice in our proportions or from often heating these Injections become too hard or Brittle. We know when they are of a proper consistence by the following Experiment; Drop one drop of it upon cold water which will immediately diffuse itself over the whole surface when the spirit will be immediately attracted by the water & the gums with the Turpentine will be left swimming on it, if this will bear raising up without breaking it is of a proper consistence, but if it breaks its too hard & much be softened till it is properly tenacious Of Watery Injections Glue dissolved in water alone makes a good minute Injection; before it is dissolved by heating its necessary to steep it in water for 12 hours then boil it upon the fire till the whole is dissolved, afterwards strain it & drop some of it upon a cold stone or any cold substance to cool that you may know its consistence; when it is somewhat thicker than a common gelly it is of a proper consistence Isinglass & water prepared in the same manner as the preceding ~ makes an Injection similar to it Gum Arabic, Tragacanth, or any of mucilaginous Gum dissolved in Water to the consistence of Cream & strained as the preceeding make a very minute Injection As the Colours mix difficultly with with these watery Injections, they ought first to be mixed well with a little of the Injection & then the remainder added to it. Of Oily Injections We often make Injections of almost all Oils as Oil of Turpentine Hogs lard Tallow &c: The oil of Turpentine is rather too thin of itself but when added to two parts Tallow is a good Injection Butter or Hogs Lard make of themselves a pretty good Injection All fine Injections require more Colours than coarse ones, for as it is to run into much smaller vessels it of course becomes more & more transparent and therefore requires such a quantity of colour as to render it opaque even when it is most minutely separated on diffused within in very small vessels or on any surface Of Common Injections The corroding Injections are too hard for several purposes & the fine ones too soft therefore we need something between them, some of which must be softer than others The hardest is Rx Resin 3 ounces Tallow 2 ounces Wax 1/2 ounce Colour sufficient for an Injectn. is Rx Resin 2 ounces Tallow 2 ounces Colour sufficient for an Injection These are generally used when the part is intended to be dissected Varnishes Turpentine Varnish Yellow Resin 14 lbs Oil of Turpentine 16 lbs, boil the water out of the Resin & then add the Oil of Turpentine from the fire. White Hard Varnish Mastich & Gum Juniper a 1 grain Alcohol 8 grains ~ Brown Hard Varnish Shell Lac & Seed Lac a 1 1/2 grains Gum Juniper 1 1/2 grains Alcohol Galls. 2 clean the Gums from dirt & bruise them pretty small then put them in the spirits & dissolve them in a Sand heat The Spirit of Sea Salt is the corrosion commonly used by Anatomists The part to be Injected must be macerated in water blood warm 2 or 3 days so as to relax the vessels & soak out all the blood in them, then having a proper sized Syringe with pipes of different sizes, fit one of the pipes into the vessel & fasten it well with a ligature bringing the ligature round the cross piece to secure it the latter. The part to be injected lying in the warm water & the Syringe and Injection being warm, the Syringe is to filled with the Injection, the end of it put into the pipe & kept fast & the Embolus of the Syringe pressed gently down with the breast till the part is sufficiently injected or the syringe when it is to be filled and emptied as before if necessary ~ Med. Hist. MS B 158 Med. Hist. MS. B 158