price 50 ls Ellis Lewis S.M. Ellis Ellis Ellis Lewis 22d of Nov. 1814 many men Joseph Graffer Chapman’s Dr,, Darwins theory of the Modus Operandi of As_ _tringentia is that they stimulate the Absorbents to carry off the interstitial fluid and by that means produce a condensation of the simple solids Stimulants Dr. Chapman ranks among the stimulants emmen agogues diuretics emetics Cathartics erodents epispastia chalogogues &c. The primary action of Medicines upon the stomach & nerves among the class of emetics are those that increase the secretions of urine sweat promote expectoration absorption Emetics are generally administered in intermit -tent fevers to prepare the stomach for the re- ceptaion of tonics, barks, &c. When diarrhea depends upon a superabundance of Bile in Dyspepsia Hysteria ascites Cynenche Trachealis Emetics of use in haemophysis in Menorrhagia Administered in nauseating doses in Rheuma -tism when attended with intermittently by producing relaxation of the system. Chapman’s Lectures Dec,, 20th [18??] Diaphoretics those Chapman ranks as sudoriferous and diaphoretics the former promoting sensible perspiration or sweat the latter insensible All the diaphoretics operate either by increasing the force of the circulation or by exerting the action of the vessels on the surface the diaphoretics are deemed highly beneficial in most fever they operate by taking off the constrict tion of the surface in inflammatory fevers the diaphoretics not to be resort- ed to until the action is lessened in inflammatory fever the mildest to be employed. The beneficial effects of Diaphoretics in typhus. vvi. Dover’s powder formd of nitre ipecacuanha opium] Wine whey fumigations to the lower extremities to promote sweating Decm. the 27 1814 Chapman on emmenagogues Those are medicines that promote the menstrual discharge Dr. Chapman con- siders the uterus as a secretory organ and liable to the glandular diseases and suitable for the secretion of a fluid (the catamenia) that is different from blood among the first and one of the most powerful emmenagogues Chapman considers Polygala seneca or rattle snake root. a diffusible stimulant Chapman considers this as a most active medicine this to be made into a decoction of an ounce to a pint of water to be boiled one half and given to the amount of 4oz. in 24 hours The uterus next to the stomach exercises the nearest dominion over the animal economy. all diseases incident to the human frame as more or less aggravated by the permanent suppression of the senses 29th of Dec. 1814 After Seneca the next medicine that claims our attention is savine, this is singularly prone to produce hemmorrhagy particular ly of the uterus. this medicine produces a stimulus in which is especially directed to the uterus in amenorrhea or suppression of the menses it is evident it arises from an imperfection in the circulation of those parts it is in such cases sa- vin may be advantageously employed the dose to be given is 30 gr. of the substance in Powder. the essential oil of this plant is also a favorable way of administering it in the dose of 6 drops Chapman considers Rubia tinctorum as a medicine worthy the notice of practitioners given in the dose of 30 gr. Rosmarinus officinalis is considered by many writers an emmenagogue in the dose of half a pint of the strong infusion at bedtime [illegible] as possessing the stimulant properties may also be ranked Jan 3d 1815 In amenorrhea the next medicine that claims our attention is iron the rust of iron combined with barks and given in the form of an electuary but the neatest manner of administering it is in the form of cha- lybeate wine composed of the rust of iron one and a half ounce, gentian and orange peel 1oz. mixed with a quart of port wine given in the dose of a table spoon full two or three times a day this preparation as a tonic is considered by Chapman as of the first importance the myrrh is another med. not to be omitted in the treat ment of this disease particularly chorions or retention of the menses the form of ad- ministering this medicine is in combination with Zinc in the proportion of 1 gr of Zinc to 3gr of Myrrh to be adminis- tered 3 or 4 times a day frictions to the hypogastric region and a full and nourishing diet is found to contribute to the cure of the disease. Application of blisters to the inside of the thighs as high up as possible are of essential service in amenorrhea or suppressed menses the tincure can - is a useful remedy in some cases given in the dose of 15 drops 2 or 3 times a day it accelerates the pulse and causes a great flow of the urine Menstruation is sometimes per- formed with pain small portions being discharged this variety is called dysmenorrhea this form is united with increased action, bleeding the cold bath administered of camphor combined with opium 1gr opii oz of camphor sometimes in order to alleviate pain an ingection of opium Laudanum combined with castor oil January 30 1814 Chapman on anthelmintic anthelmintics are such medicines as are suited to destroy or expel worms from the alimentary canal the worms may be divided into two classes the round and the flat of the round class is the lumbricalis and ascarides of the flat is the taenia Every disease to which Children are incident are more or less aggravated from the irritation of worms in the alimentary canal the symptoms of worms in the intestinal canal is a fever flushings of the face pain of the bowels frequent attacks of diarrhea the breath common ly foetid sometimes a dry cough a frequent packing of the nose Among the most active remedies for worms is purges of calomel and aloes The next medicine that claims our attention is spigelia or pink root to be exhibited in powder or infusion the dried root to be given in powder to the extent 10gr evening and morning in the in- fusion an ounce of the root to be boiled in a pint of water one third and given to the extent of one ounce night & morning this medicine to be administered with caution as it is liable to bring on convul- sions and spasm after administering the pink root a sufficient length of time a cathartic to be exhibited the next an- thelmintic that claims our attention is the foetid hellebore the dried leaves given in powder to the extent of 10gr. I am next to say something of the as- carides known by a continual itching of the anus among the most powerful remedies is a combination of calomel and aloes exhibited as a purge 1 oz or two drams of aloes dissolved in a pint of milk form an excellent injection an infusion of tobacco but among the most efficacious remedies is an injection of a solution of a tablespoon full of salt in half a pint of water the most difficult of the worms to expel is the taenia the most efficacious remedy in this are purges of calomel the cowhage is another well known remedy the oil of terebinth 2 oz January 18th 1815 Chapman on Narcotics These are the medicines which di- minish the sensibility or irritability of the system and thereby the motions and power of motion in it they are sometimes called Soporific or Hypnotic medicines as they induce that remarkable cessation of sense and motion in which sleep consists we must conclude from our observations that the operation of those medicines is upon a matter in common with the whole nervous system From many phenomena it appears that the mobility of the nervous fluid may be more or less at different times and particularly that it may be affected on these restrict by external bodies applied to the nerves Such then we con- ceive to be the operation of Narcotic medicines that they diminish the mobility of the nervous Power. It is proper to observe that the effects of our narcotics appears first in those functions in which the mobility of the nervous fluid ad- mits the most readily of a change that is the animal functions in the cessation of which sleep consists Narcotics when first exhibited excite the functions both of body and mind the force and frequency of the pulse is increased this operation of narcotics it has been difficult to explain but it seems neccessa -ry to assign some other cause than the direct stimulant power of the substance applied and it appears to be that resist- ance and consequent activity Which the animal economy is suited to oppose to every application which has a tendency to hurt it this power is called the conservatrix et Medicatrix natural we therefore conclude upon the while that the operation of Narcotics is always directly sedatively Of the class of Narcotics the first medicine that claims our attention is opium in the employment of this medicine in intermittent fevers it should be ex- hibited about half an hour before the expected paroxysm the most useful preparation of opium is a Dover’s powder given in order to produce relaxation of the surface some writers assert the opium should never be employed in the plegmasiae when venesection is demanded as a general rule this is certainly a good one. Opium has a bad effect in the incipient pneumonia. when it is to be exhibited in this disease as in the middle stage as it always has a tendency to stop the excretion of mucus on the bronchia it should be given in combination with some expectorant [illegible] 2dr. of liquorice. 1 dr of Antimonial wine of water 3oz. in parapneumonia after the inflammation has subsided 2dr of Nitric acid 8dr. of water and Laudanum in proportion in the dose of a table spoonful every hour in Rheumatism this medicine is not to be administered until the evacuating plan has been carried to a great extent opium exhibited alone never fails to aggravate all the symptoms of this disease in sec- ondary syphilis Opium combined with Mer cury is of the first importance opiates in retrocedent gout never fail to produce salutary effects in uterine flooding opium is of eminent service. in all the nervous affections some writers assert that this medicine is of service from any anon practice I can say but little in its favor Except in that variety called tetanus Opium exhibited in large doses may be found of benefit In the cure of Mania proceeding from drunkenness the opium exhibited in the doses of 4gr. with a cor- responding dose of Camphor will be found of eminent service given to the extent of 60 or 70 daily Next to opium as a diffusible stimulus and one of the most importance is the Volatile alkali this medicine is used in nervous affections during the first stage of syphilis of the inflammatory symptoms exist with delirium the volatile alkali has best be deferred until those symptoms have subsided the or- dinary dose is 5gr every 3 hours 1 dram of gum arabic 1dr of volatile alkali of water 5oz this med. is much employed in intermittent fever to be given before the accession of the hot stage in the Pyrosis or water brash this is an excellent remedy in that gastric affection of the stomach called the side head ash the ammonia given in moderate doses gives immediate relief January 25 1815 Camphor this substance is obtained from a tree called the laurus camphora what we employ is chiefly the growth of Japan its operation seems to be entirely sedative and we take its being of that kind of the stomach itself which occasions the indi gestion of food which is constantly observed after its exhibition in a large dose. in the exhibition of camphor the force and fre- quency of the pulse is not increased February 25 1815 Dorsey on the venereal the period at which this disease be- gan has been the subject of much dispute it has been supposed that Columbus’ followers brought it from Hispaniola to Europe Some authors declare that gonorr hoea never produce chancre Dorsey supposes this to be a doubtful position Women with gonorrhoea have been known to communicate chan- cre to the men Mr hunter made an experiment in which he made a puncture on the penis and introduced gonorr- hoeal matter a chancre was the result Experiments prove uncon- testably the matter of gonorrhoea to be only a modification of that of Chancre from facts brought forward I conclude that the matter of gonnorrhoea and chan cre are only modifications Dorsey on gonorrhoea in men the Urethra is the seat of the disease in woman the vagina and urethra in general two or three days elapse after contamination before the disease makes its appearance some times only a few hours before the discharge comes on inflammation supervenes attended with an itching of the glans penis which extends along the urethra a burning pain the glans penis inflamed and appears polished on the external surface after the inflammatory symptoms have run high chordee frequently recurs the matter discharged Dorsey Dorsey on inflammation Dorsey’s theory of inflammation the increased redness arises from the dilation of the small vessels which become sufficiently capacious to admit the red globules to admit the red globules in large quantities on the generation of new vessels the swelling seems to de pend on the dilatation of the vessels to the plethora state of the arteries and veins to the exudation of coagulating lymph in the cellular substance to the interruption of absorption. Treatment of Inflammation. By the Antiphlogistic Regimen Evacuate Bleeding near the part affected Blisters applied to the different parts purging nauseas doses of emetics The patient to have an abstemious diet Burns & Scalds Dorsey gives 3 different degrees the first is separation of the cuticle the 2d is ulceration the 3d mortification effects The 1st degree when of considerable extent is attended with great danger in the last state shiverings & hectic fever Treatment when inflammation runs high the antiphlogistic plan when there is danger of mortification strengthening medicine & stimulants the local applications are linen dipt in spirit of wine oil & lime water carbon the Basilic ointment. Dorsey disapproves of the use of cotton. Dorsey on wounds of the veins Wounds of the veins not attended with any serious consequences except from the hemorrhage the internal coat the seat of inflammation ad- hesions forming produced by bloodletting the wound not healing by the first intention Extravasation in the cellular texture Treatment in cases of slight inflamma- tion bringing the sides of the orifice in contact and compression applied immediately over it the application of Blisters The matter discharged in gonorrhoea is generally of a yellowish colour some- times mixed with blood inflammations sometimes attacks prepuce and occa- sions phymosis the inflammation begins at the glans penis and extends along the urethra sometimes the bladder and even the kidneys become July 12 1814 Chapman on tonics Those are medicines that exercise a wide dominion over the animal economy and as their excitement is gradual it goes off gradually and is not succeeded by increased debility the first and certainly the most important of those medi- cines that I shall mention is the Peruvian bark of which there are several species of which the yel- low is the best when obtained pure in the administration of bark in the intermittent fever the earlier it is given the bitter in order to pre- pare the system for the operation of the bark Cathartics and Emetics are to be administered to throw off peccant matter contained in the stomach or intestines besides this Evacuation venesection is sometimes imperiously demanded in intermit- tent fever before the exhibition of the bark it is supposed that during the cold stage congestions of the blood vessels of the liver and other viscera take place the bark to be discontinued during the accession of the hot stage the usual way of administering the bark is in powder the doses given are to in general are from one to two drams sometimes the great irritability of the stomach will not admit of the use of the bark even in the smallest dose the infusion given in conjunction with the polygala seneca may then be em- ployed with advantage the bark is inadmissible in the synocha on inflame- matory fever when the gout or Rheu- mastism takes on the intermittent form the bark may be employed with advantage in passive hae- morrhagy the following prescription is sometimes employed bark [illegible] ounce a Aqua Calus put 1 in dyspepsia the bark combined with preparations of iron is the remedy the bark consists of tannin gallic acid gum and resin the bark is generally given in substance or in some fluid milk is the best the infusion is made by putting one dram in a pt. of boiling water the dose is according to circumstances the decoction is made by boiling an hour and a half 2oz of the bark in a pint of water in a bottle put in wa- ter the dose is a wine glass full every 2 hours when it cannot be kept on the stomach the bark may be entangled in mucilage of starch and be given as an enema Feb. 17 and tranquilizing the stomach the decoction to be given to the extent of [illegible] an ounce. Colombo as a tonic next deserves our notice to be exhibited in Powder tincture and extract in the decoction the virtue being lost it should not be employed The next article I shall mention is the hiroma centaurium our forests supplies us with two kinds of bark the cornus florida on dog-wood and the common ned willow this is a valuable bark it grows exclusively in swamps the dog wood is used as a substitute for the peruvian bark to be exhibited in the same form and dose I next shall mention the prunus virginianis or common wild cherry tree of this country of late years the bark has acquired con- siderable reputation in curing intermittent and remittent fever I have also experienced its good effects in phthisis pulmonalis it will restrain diarrhea attending hectic fever in the exhibitions of the bark for the cure of intermittent fe- ver it is to be given in the form intermissions of paroxysm I shall next lay before you an account of the different preparations of iron those are certainly some of the most important articles of the Materia Medica in its operation iron evinces all the effects of a permanent tonic under the use of iron the color of the blood becomes more florid it invigorates the system it is In the discussion of the Metallic tonics the next that of- fers itself is copper as a medicine copper is not employed in the crude state the sulphate of copper or blue vitriol given in the dose of 1gr. is employed in intermittent fever 1gr dissolved in an oz of water forms an excellent injection in effect Cuprum ammoniacum is another preparation of copper to be employ ed in Epilepsy copper might be ad- vantageously employed in dropsy copper combined with acetic acid forms verdigris or the acetate of copper this forms an escharotic the preparations of zinc are emp loyed as a tonic the flowers of zinc to be employed in epilepsy the white vitriol in nervous and spasmodic af fections in epilepsy 2gr of the white vitriol 10gr valerian 13 of the Peruvian bark forms an excellent prescription as an injection in gonorrhoea 8gr. of the white vitriol 10gr of the sugar of lead a ounce of the gum arabae and 8oz of water the lapis calima nalis mixt with Armenian boles in equal proportions is an excellent ap- plication in the chafings and excori- ations of children I must next treat of this precious metals the first of which I shall mention is silver the only preparation employed in medicine I shall next speak of gold it may be employed in minute division in the form of an oxide and also the muriate of gold these preparations in said to cure warts chancres lues venera Among the acids the most important tonic is the sulphuric acid it is chiefly employed in the form of our Elixir vitriol it is employed in haemorrhagies externally applied of forms an escharotic In itch 1 ounce of the sulphuric acid to an ounce of lard of 1 ounce to a quart of water will cure the most invertible itch I shall next proceed to speak of arsenic this is never employ ed in its crude state when exposed to a high temperature it becomes oxidated the oxid made into pills the dose 1/8 or 1/8 of a grain Fowlers solution The most common way of exhibiting this medicine is in the form of Fowlers solution the dose from 10 to 15 drops or in the form of the arsenate of potash the dose from 1/8 to 1/10 of a grain I have always prescribed Fowlers solution when the arsenic is to be pre- scribed alone the oxid when employed in combination with some other article in intermittent the arsenic is of the first importance when the intermittent borders on typhus or there is any dropsical symptoms the arsenic is not to be employed This medicine compared to the Peruvian bark is decidedly inferior In its operation arsenic is exceedingly prompt and if it should not show its good effects at the end of three days it should be discontinued it has been considered well adapted to acute Rheumatism associated with intermittent fever this medicine has been recommended in nervous diseases tetanus arising from wounds this medicine in the form of Fowlers solution combined with laudanum is recommended it is employed in healing obstinate ulcers by being given internally and applied to the ulcer Geranium maculatum or the spotted geranium grows spontaneously in all parts of Pennsylvania it is an excellent remedy in haemor -rhagy in chronic dysentery and Diarrhoea 1819 June 18th Received of Doctor Joseph Griffith Eight Dollars & Twenty four cents in full of ale demands [illegible] Thos. Garrett James Barton on stimulants Stimulants of use in all diseases of debility. Leeches ranks among the stimulants administered in tetanus in affections of the eustachian tube in congestions of the blood vessels of the head in amaurosis Dialagogues producing Salivation mercury the principal Salivant administered internally by be- ing taken into the circulation Mercury acts by chan- ging the action of the parts to which it is applied or by exciting a new action different from that created by the venereal virus received into the Circulation This is Hunters theory of the action of mercury Sallivation produced by fumigation the cinnabar of Mercury to be used for the purpose. In order to prepare the system for the action of Mercury the different Evacuants are to be employed viz. Bloodletting, purging, by stimulating sinapses & by putting the patient in the warm bath. Expectoration is produced by such medicines as promote the discharge from the lungs, the alliacea generally speaking are Expectorants Coffee in particular constitutions Bartons theory of gums being expectorant by rendering the discharge more tenacious the thinner parts are absorbed Emetics Ipecacuanha generally speaking has the Power of throwing off noxious substances intro- duced into the stomach, it generally operates in a short time. An application to the abdomen of a poultice of tobacco & vinegar produces immediate vomiting useful in throwing off Poisons Received in the stomach In inflammation of the abdominal viscera Emetics are Contraindicated. Action of Cathartics Cathartics increase the secretions of Bile of the Pancreas the small vessels that empty upon the inner surface intestines During the action of Cathartics irritability is increased & perception is more acute In different fevers Cathartics are of considerable benefit & also in apoplexy some of the Cathartics particularly Sulphur of use in haemorrhoidal affections in uterine haemorrhagy Diaphoretics Diaphoretics or sudorifics are such medicines as promote perspiration or increase the secretion by the skin They are of pecular benefit in the Rheumatism in retrocedent gout in the disease of diabetes in cases of Calculus. Diaphoretics generally speaking have more certain effects given in the morning Dover’s powders, formed of Ipecacuanha Opium & nitre. given in gout Emmenagogues are such med -icines as promote the menstrual discharge and are suited to most diseases of the uterus the whole class of Bitters rubia tinctorum the most stimulating are aristolochia ser -pentaria oil of Savine tincture of hellebore or Melampodium Valeriana officinalis from the Mineral kingdom the different prep -arations of Iron & those are all of great ability in obstruction or retention of the menses the Cold bath, frictions, Emetics & Cathartics are often of considerable service of the diuret ics, digitalis is the most powerful Emmenagogue. Emmenagogues are of most service ad- ministered a few days before the Catamenia are expected to make their appearance. Barton on the Practice Barton on fevers that all fevers are com prehended in one genus the symptoms attending fever is a sense of coldness especially on the extremities the coldness Barton’s Lectures. Nov. 29th 1814 The coldness to be considered as a sensation although there is in reality a slight diminution of heat especially on the Extremities this coldness generally comes on with a stupor a change in the circulate is a concomitant of fever a quickness of the pulse seldom under 92. the paroxysm of cold followed by that of heat Increase of heat not to be considered as a sensation as there is a preternatural heat at the time existing attended with a frequency of pulse the heat never ex -cedes 112 degrees debility the effects of all fevers a sediment found in the urine particularly in intermittents resembling brick dust this is what is called the lateritious sediment spontaneous sal -livation sometimes occur in fevers and its salutary effects Of Particular fevers. an intermittent fever consists of Paroxysms which are suc- ceded by apyrexia the different forms or va- rieties of intermittent fever are the quotidian tertian and quartan the double quotidian or that form in which there are 2 hot fits and thus Cold in the course of 24 hours this is to be rather considered as a Remittent the intermit- tent generally consists of 3 stages the Cold the hot and the sweating Death during the Continuance of the Cold stage seldom occurs Except in old persons there are 2 distinctions of intermittent the vernal and autumnal the vernal generally speaking attended with a phlogistic diathesis the autumnal at- tended with putrid symptoms and having more propensity to run into typhus Vernal in- termittent sometimes produce salutary effects on the system by removing nervous affections Rheumatism Gout and congestions of the viscera but it is agreed on all hands that they do more harm than good Bartons Lectures Dec.. the 1st 1814 favorable symptoms of intermittent fevers are spontaneous Sallivation Eruptions about the mouth affections of the Parotid gland cutaneous eruptions attended with itching. The unfavorable symptoms are a dryness of the skin diminution of the quantity of urine abscesses in the groin especially in the beginning Causes of fever Miasmata arising from putrid bodies Idio Miasmata exhalation of living Bodies Bartons Method of treating intermittent fevers In the Exhibition of barks they should be given in combination with a small por- tion of opium in order to prevent it from running off by stoll. a small porti- on of Calomel combined with the barks is in some cases of service. the External ap plication of bark to the abdomen in some cases of considerable benefit there are several barks though not so certain in their effects can be substituted for the Cinchona-officinalis viz. the salix-alba the cornus or common Dogwood the terra japonica a remedy in intermittents prep- arations from the Mineral kingdom vitra of album or white vitriol Flores Lince Blue vitriol of the preparations of iron the Carbonate of iron of service particularly in enfeebled Constitutions but of all the rest arsenic is of the most effectual service given in the form of the mineral solution in the dose of 5 drops but if it should not show its salutary effects at the end of 3 days the administration of it to be discontinued the arsenic to be exhibited only in such intermittents as are attended with an in- crease of arterial action of the saline preparation Alum in the most efficacious given in the dose of 3gr. 3 times in 24 hours Treatment the Exhibition of opium in the dose of 2gr. in order to prevent the chill application of blisters to the ancles and wrists sinapisms &c. this plan to be pursued of before the accession of the Cold stage. During the hot stage tonics is generally speaking hurtful by increasing the arterial action. this is most favorable time for the Exhibition of arsenic the acetate of lead may also given with advantage during the fit opium administered cautiously may shorten the fit alleviate head-ache and procure refreshing sleep Barton in most cases disapproves of the use of opium Neutral salts nitre combined with anti- monials in order to procure sweating Barton on continued fevers continued fevers may arise from marsh miasmata Idio miasmata or the exhalation of living Bodies a frequent cause of continued fever synocha typhus and synochus to be considered as one genus. Barton considers nervous fever as a term applicable to the typhus the Nervous system being much affected in most cases from the beginning the symptoms of typhus are small pulse and weak the urine in small quantity and turbid the typhus generally attended with but little increase of heat the symptoms go on gra dually increasing for several days when the patient is confined to bed with difficult breath -ing anxiety vertigo pain of the head a wrin ging of the ears pain about the temples the typhus and yellow fever may be considered as nearly of the same nature the most distinguishing mark is that in the latter acute inflammation of the eye generally takes place while in the former the inflammation is chronic as the symptoms advance great prostration of strength a sensation of pressure of the chest pains of the back and limbs the state of the tongue dry and covered with a crust resem -bling brick dust. resembling in colour red chalk with the skin in general parched petechia or eruptions of the skin of a purple colour it then assumes the name of spotted fever the breath the urine and the stools become foetid. The favorable symptoms are a gentle di- arrehoea a gentle diaphoresis abscesses in the groin and of the parotid gland. deafness when accompanying the last stage. unfavorable symptoms a violent diarrhea gangrenous patechia the eyes much inflamed the tongue covered with aphthae of a dark colour Sir John Pringle has taken notice of 3 stages of typhus fever Barton considers this as a necessary division. The first stage is when the symptoms go on gradually increasing before the patient is confined to bed. The 2nd stage when the symptoms have increased considerably patient confined to bed The third stage the pulse sinks very low attended with delirium pain of the head gangrenous patechia. Barton’s treatment of typhus fever Tartar emetic given in moderate doses arrests the progress of the disease, diaphoretic mild Cathartics, Castor oil in some stimulating vehicle, rheubarb a slight sallivation of beneficial effects. 2d stage slight Bloodletting particularly when peritoneal inflammation exists Emetics of use in the 2d stage when attended with nausea to be exhibited in moderate doses opium when the disease is attended with delirium, subsultus tendinum & may be considered an excellent remedy Barton’s favorite medicine and one that he supposes to be peculiarly a -dapted to this disease is the volatile alkali or ammonia this medicine is adapted to an irritable state of the stomach. Camphor in Combination with opium Camphor externally ap- plied in petechiae or eruptions of the skin musk may be exhibited as a diaphoretic and anodyne with considerable advan- tage. when the breasts are very much af fected asafoetida of benefit in the dose of from 50 to 60gr. in the 24 hours. Peruvian Bark when the disease assumes an intermittent form port Wine of berry wine and injections of wine whey into the intestines When more powerful Stimulus are required Brandy of the most beneficial effects. tincture cantharides sometimes of marked advantage sinapisms or mustard plasters composed of 1 part of flour of Mustard 3 of flour and mixed with vinegar applied to the wrists and ancles affusion of cold water of benefit not to be applied in the sweat ing stage a solution of corrosive sublimate in brandy applied to the breast by means of sponges in difficult breathing. Dec. 20 1814 Barton on phlegmasia or Inflammatory diseases the general symp toms are pulse frequent strong and hard the urine of a reddish colour Treatment the Antiphlogistic plan Evacuations Bleeding purging diaphoretics Rheumatism Causes Miasmata application of cold when the body has been healed Rheu- matismus Metallicus or that arising from working different metals a frequent cause of acute Rheumatism is the sudden suppression of Evacuations particularly the flux of gonorrhoea this variety to be cured by renewing the discharge from the urethra. predisposing Causes violent exertion of muscles animal diet large evacuation the Pyrexia accompanying Rheumatism attended with an exacerbation in the evening Mild sweating commonly accompanies this disease. The Chronic Rheumatism Which when attended as it commonly is with but slight fever Barton styles Pyrexia subnulia. in the chronic the application of heat abating pain while in the acute it increases pain the pyrexia subnulia attended with a difficulty of mov- ing the limbs affected, Some writers as- cribe this disease to an acrimony of the fluids Barton admits of the prob- ability of this. Treatment of acute Rheumatism as this is attended with an inflammatory diathesis the antiphlogistic plan. vegetable diet Cathartics Diaphoretics Calomel in Combination with Jalah the saline purgatives are deemed highly efficacious Topical Bloodletting Barton prefers Cathartics as Bloodletting is liable to cause a Metastasis of the disease to the internal parts the Exhibition of Nitre is recommended in this dis ease in the dose of half a Drachm after Bloodletting a small dose of opium in order to alleviate pain a valuable diaphoretic in this disease is Dover’s powders formed of Opium Ipecacuanha & Nitre Mercurials by exerting a slight salivation prepare the constitution for the reception of medicines. Arsenic an important remedy in acute rheumatism this to be considered as specific. it is of peculiar benefit in rheumatism of the Chest the dose from 5 to 10 drops 3 times in 24 hours administration of bark during the apyrexia. Barton’s treatment of Anthrodynia or Chronic Rheumatism. this Dr.. Cullen supposes to depend upon an atony or loss of action in the muscular fibres and blood vessels. Guiacum combined with gum- arabae in water is considered as a valuable medicine. The volatile tincture this medicine acts as a purgative and mild diaphoretic the balsams produce salutary effects by their stimulating powers. a preparation of 1oz. of turpentine ½ oz. of sugar ½ oz of gum arabae yolk of an egg a table spoon full to be administered 4 times in 24 hours. the volatile alkali. Mustard seed not to be considered among those remedies of the least importance it operates as a diffusible stimulus. external appli- cations of Camphore frictions &c. Electricity of considerable benefit in Chronic rheumatism of the local ap- plications Blisters is the most valuable Decr.. 26th 1814 Barton on Nephritis or inflamma- of the kidney a disease attended with py- rexia. with pain in the region of the kidney the pain shooting along one or other of the ureters frequent passing of urine. this disease frequently attending gout and Rheumatism. the fever attending this disease of the nature of synocha vomiting attending the nephritis vera Remote Causes Falls or blows on the loins violent riding. Barton considers as a remote cause Aerids taken into the circulation and carried to the kidneys such as tincture Canth. digitalis etc. sometimes the sud- den retrocession of gout from the inferior Extremities The favorable symptoms in this disease a large discharge of ur- ine of a black colour Profuse Evacuations of the haemorrhoids vessels. Treatment Bleeding both general and topical Cathartics large quantities of mild drinks a watery infusion of the ura-ursi blis- ters applied over the region of the kidney Opium may sometimes be administered with advantage sinapisms to the lower Extremities when it arises from retrocedent gout Barton on Cystitis or inflammation of the bladder known by pain of the part this is gener ally attended with fever difficult frequent and painful making water the cause of this disease Barton principally ascribes to the excessive use of diuretics digitalis Cantharides etc. Treatment large and repeated bleedings fomentions of the part the temperate use of foxglove in ischemia or suppression of urine Decr. the 26 1814 Barton on hepatitis or inflammation of the Liver a disease attended with pyrexia pain in the right hypochondriac region generally obtuse difficulty of breathing distention of the right hypochondriac region a dry cough attending this dis- ease a yellowness of the shin frequently takes place the remote causes This disease is sometimes induced by Gold applied so as suddenly to check per- spiration fracture of the skull frequent by produces this disease Barton supposes this to be owing to the sympathy exist- ing between those parts This disease may terminate in three viz. resolution suppuration and gangrene when the disease terminates by resolution it is owing to a large evacu- ation of blood from some part or other the right nostril for instance when the dis- ease terminates by suppuration sometimes owing to adhesive inflammation having taken place between the liver and diaphragm abscesses have been formed and the pus has been discharged by the bronchia some times it is discharged by the biliary ducts Treatment bleeding largely and repeatedly of the symptoms should not abate applications of blisters to the part purgatives in this disease are important remedies Enemata afford considerable relief Digitalis of benefit in this disease Barton considers mercury as a medicine of the first importance this medicine by producing a slight salivation is attended with the most salutary effects this medi- cine not to be administered until the inflammatory symptoms have been subdued by evacuations. The bark has been found beneficial when the Pyrexia which is a concomitant of this disease assumes an intermittent form Decr. the 24 1814 Barton on Icterus or Jaundice this disease generally accompanied with fever attended with a yellow colour of the skin and eyes the urine of an observe red colour the variety of jaundice that de -pends upon a stone in the biliary passages known by an acute pain of the parts par- ticularly after eating this is the most frequent form Barton has however na- med several other varieties this disease is generally attended with a costive habit and the serum of the blood of a yellow colour The most frequent causes of this disease are obstructions in the biliary passages & the most frequent cause of those obstruct- tions are caculi in the biliary ducts this variety Barton designates by the term of icterus Calculosa jaundice may also arise from worms passing from the Duodenum to the biliary passages sometimes the disease arises from spasmodic constric- tions of the biliary passages when the disease arises from this cause it is irreg- ular in its symptoms. a jaundice may arise from the absorption of bile from the alimentary canal the bile may be forced into the extremities of the hepatic veins by a regurgitation and carried into the vena-cava Treatment Bleeding of considerable benefit when the patient experiences great pain and irritation of the parts from the pas- sage of a calculi Barton considers cathartics as of the first importance in this disease jalap combined with Calomel to be employed in this disease when it arises from worms in the biliary passages Emetics are found to relieve the symptoms Ipecacuanha to be preferred considerable benefit will sometimes be derived from putting the patient into the warm bath during the operation of the Emetic. Blisters applied to the region of the liver mercurials employed so as to produce a salivation in the form of Calomel has been found to contribute much to the cure of the disease Barton recommends in some cases the volatile alkali the muriatic acid has been employed by some practitioners and found to be of singular benefit Barton recommends Opium also the external application of laudanum to to the region of the liver Decr. the 29th 1814 Barton’s Lectures Phelgmasiae of the thoracic viscera On Pleurisy and Peripneumonia as these two varieties differ very little in their symp- toms and the treatment is nearly the same Barton considers it unnecessary to treat of them separately he has accordingly treated of them together at the same time attending to the symptoms by which you may distinguish them asunder; Peripneumonia attended with fever of the inflammatory kind, sy- nocha; the pain of the obtuse kind, the pulse soft, the face flushed, a sensation of the stricture of the breast. Pleurisy A fever of the inflammatory kind pungent pain of the side, dry cough; the pain in- creased by inspiration the pulse hard in all inflammations of the breast this disease may terminate in 3 different ways When the disease terminates by res- olution it is in consequence of a large Expectoration having taken place, or an Evacuation of blood from different parts may supply the place of an Expec- toration The Symptoms of suppuration having taken place is an abatement of pain dry cough sweatings of the head and neck difficulty of breathing continues when this pus is discharged into the cavity of the thorax it occasions Empyema the dis- ease sometimes terminates by a serous effusion into the cavity of the thorax constituting hydrothorax. Predisposing causes. among those may be named a laborious Exercise in the open air, a rheumatic habit the sudden application of Cold to the body when overheated Miasmatic Exhalation whatever heats and stimu- lates the system. The unfavorable symptoms in this dis- ease are a violent pyrexia from the first beginning a frequent and violent cough aggravate the symptoms and as a free discharge from the lungs is sufficient of- ten for the cure of this disease a dry cough may be reckoned among the unfavorable symp toms when a delirium comes on in the ear- ly part of the disease it denotes great danger when the disease continues beyond the 14th day it generally terminates by supparation Treatment The indications of cure in this disease is pre- cisely the same as in all inflammatory fevers the Antiphlogistic plan to be obser- ved in the management of this disease the first remedy to be employed is bleeding the necessity of Bloodletting in part may be superseded by the early application of blisters but bleeding largely and repeatedly is one of the most Effectual remedies immedi- ately after the application of a large blister to the thorax a second bleeding should be performed in order to counteract the slight irritation produced in the system and which is always a consequence of the application of blisters. Purging are remedies of the next importance the saline salts are in most cases preferable owing to their refrigerant nature sometimes more powerful Cathartics are necessary such as calomel combined with Jalap gamboge etc. Barton recommends digitalis in this disease its operation in reducing the arterial circulation it is of peculiar benefit when the disease is expelled to terminate in dropsical effusions. inhaling the steam of warm water impregnated with vinegar is sometimes of peculiar benefit in promoting expectoration Emetics can be advantageously employed in the variety of this disease called biliary pleumonia. barks employed when the pyrexia assumes an intermittent form. January the 2d 1814 Barton on Cynanche or inflamma tions of the fauces of which there are five species a Disease attended with Parusia not always of the inflammatory kind those five varieties are so nearly allied Dr. Barton thinks it unnecessary to trial of them separately Cynan- che parotidea principally affecting the ton sils and mucous membrane lining the fauces to be treated by astringent gargles principally a decoction of oak bark and allum when the inflammation extends over the contiguous parts and into the Eso- phagus it constitutes Cynanche pharyngea to be treated by evacuations bleeding Cathartics blistering etc. Cynanche parotidea attended with an external tumor of the par- otid gland. in this disease Metastasis sometimes takes place to the testicle in the male & to the mammae in the female it is attend ed with lassitude and anxiety for several days before the swelling commences a difficulty of moving the jaw before the tu- mor makes its appearance it is then at- tended with pyrexia when Metastasis takes place to the testicle there is an increase of pyrexia great pain of the parts this dis- ease is sometimes supposed to arise from marsh-Miasmata, Treatment When the disease tends to Metastasis blisters to be applied over the parotid gland Evacuations bleeding Cathartics etc. sometimes the fever attending this dis- ease assumes the form of typhus the pulse sinks and the patient becomes debilitated the plan of treatment is then to be changed. Cynanche trachealis sometimes termed trachilis a [illegible] name indicating that the trachea is principally affected this dis- ease is also called croup and sometimes lives Jan. 3rd 1815 a disease attended with difficult respiration shrill cough the fever attending it a true synocha, the voice much altered resembling the barking of a young dog, deglutition but little impeded. this disease comes on in the form of a catarrh and continues several days before the croup is formed the eyes are swelled denoting the difficulty of respiration and the face flushed in the course of this disease spontaneous vomiting occurs frequently but in general attended with good effects Among the Remote causes of this Disease Barton mentions cold and most Atmosphere Miasmatic exhalation Sometimes worms produce this disease by taking possession of the upper part of the Esophagus and neighboring parts and continued irritation Jan 3d 1814 Barton on the treatment of Cynanche trachealis in the treatment of this disease the first remedy to be resorted to in this dis- ease is bloodletting it is unequivacably a dis- ease of inflammation but bleeding is not always necessary Barton mentions cases in which the disease has done well without venesection haying been practised topical Scarifications blisters applied to the nape of the neck sinapisms applied to the neck Emetics in this disease are remedies of the first importance in true inflammatory croup the Emetics not to be exhibited until after one venesection has been practiced. The following are the emetics Chapman recommends in this disease Ipecacuanha com- bined with Calomel the calomel to operate as a purgative after the operation of the Emetic has ceased the antimonials Mustard etc. Among the medicines of not the least importance in this disease we must mention the alliaceous plants in the form of the juice or syrup which is rendered more efficacious by being combined with antimonials its operation as an Expectorant. In stagnant cases of this dis- ease Coffee is of eminent service Cynanche Maligna and Scarlatina those two diseases are nearly allied both in form and symptoms Barton differs from Cullen in this respect who consid- ers them distinct disease the Cynanche Maligna is an affection of the mucous membrane lining the tonsils and fauces attended with fever of the typhoid form Scarlatina-anginosa, from the first Beginning of this disease the patient Janr the 4th A 1814 appears to be dejected by the 2d day the fever increases with a difficulty of degluti- tion on the morning of the 3d or 4th day the patient’s face, neck, and breast, ap- pears preternaturally red the tendency to delirium is in proportion to the redness of the eye the pulse during the greater part of the disease is quick small and feeble. In no disease is the heat of the human body so much increa- sed sometimes being as high as 112° This disease affects us but once during our lives Barton considers the cynanche par- otidea as a modification of the Scarlatina Treatment of scarlatina in the first stage of this disease when it is attended with but little inflammation the Treatment is simple a light diet weak wine whey in mild Cathartics such as senna Castor oil in the first beginning of this disease an Emetic administered sometimes moderates the disease in a remarkable manner among the most valuable is the tur- bith mineral in the 2d stage blisters applied to the neck when the inflam mation runs high is considered of Emi- nent service the great heat of the skin imperiously calls for the affusion of cold water its efficacy is rendered more certain by being combined with vingar and applied by means of sponges anasarca accom- panying this disease call for diuretics at the decline of the disease Peruvian bark is found useful Dr.. James’ There are 6 different presentations the first when the child enters the cavity of the pelvis with the anterior fontanel to the right sacroiliac symphysis and the occiput to the left acetabulum. The second presentation is when the Child enters the cavity of the pelvis with the anterior fontanel to the left sacroiliac symphysis. The 3d presentation and the most difficult with the os frontis to the convexity of the sacrum. The 4th with the anterior fontanel just behind the Right acetabulum. the 5th presentation with the anterior fontanel to the left acetabulum, the 6th and last presentation and one of the most dif- ficult, is with the anterior fontanel to the Symphysis Pubis. There are 4 different stages of labour, the first is employed in opening and dilating the internal orifice of the womb the 2d in the passage of the child’s head through the bones. the 3d in dilating the external parts and the de- livery of the child. the 4th in throwing off the placenta January the 6 1814 Barton on the Exanthemata or erup tive diseases of the skin under this order the first disease I shall mention is the Mea- sles a contagious disease which almost univer- sally begins with a cold fit the cold suc- ceded by a hot stage attended with fever the eyes more or less inflamed with a fre quent discharge of tears attended with a coryza and running at the nose attended also with a dry cough the pyrexia con- siderable especially before the Eruption the Eruption making its appearance a- bout the 4th day from the first commencement of the Eruption fever the voice hoarse also accompanied by a drowsiness the eruption makes its first appearance on the hands and face and from thence ex- tends over the different parts of the Body 4 or 5 days on the 3d day the vivid redness of the spots is turned to a brownish red and in a day or two more the Eruption entirely disappears a branny desquama tion of the cuticle taking place sometimes the disease passes off without an eruption this Dr. Rush calls the internal measles when the measles occur in the spring in adults it predis- poses the system to violent attacks of the dysentery during the ensuing summer and autumn when the patient has an attack of the measles without the coryza and Eruptions he is liable to a vi violent attack of the true measles at a future period of life. Among the favorable symptoms of this disease is a mild diarrhea a moist skin, haemorrhagy from the nose an early Expectoration The unfavorable symptoms wasting sweats deep redness of the skin pain of the head and eyes after the Eruption The history of this disease show it to be of a phlogistic diathesis in the treatment therefore the first remedy and one which is strongly indicated is bloodletting large ly and repeatedly especially in those who are liable to attacks of pneumonia great oppression of the breast calls for im- mediate venesection Bleeding in the first beginning of this disease often brings out the Eruption much sooner than what it otherwise would have happened when the cough in measles is much aggravated an opiate exhibited when there in no contraindication will be found of Eminent service in allaying the cough Blisters are remedies of no small importance in measles applied to the chest sinapisms also to different parts are sometimes ben- eficial purging in this disease unless the inflammatory symptoms had best be omitted Cold applied to the surface of the body unless there is a tendency to [crossed out] phthisis pulmonalis is sometimes found of service but the avoiding the extremes of ei- ther heat or cold will be found best January the 9th 1814. Barton on small pox this disease is cal- led variola by classical writers a disease at- tended with fever commencing with some sym- ptoms of a cold stage which is soon succeeded by a hot stage and on the 3d day an Eruption which continues until the 5th day and on the 8th day goes off leaving small pits or depres- sions the symptoms of this disease are various attended with considerable pain of the Epigas- tric region great lassitude the pulse quick the fever when the disease has been commu- nicated by maculation generally makes its appearance on the 8th day when in the cas- ual way not until the 11th about the time the pustules begin to crust on the surface the patient may be considered in the great- est danger this disease sometimes brings on phthisis pulmonalis in those that are predisposed to it There are two varieties of this disease the confluent and the distinct the nearer the dis- ease approaches to the distinct form the less danger is there to be apprehended Slight Epileptic fits are reckoned among the favorable symptoms it is admitted on all hands that the disease is lighter in Children than with adults among the unfavorable symptoms are severe pains in any part the fever of the fever of the typhoid form the pustules filled with a bloody ichorous matter; a shortness of breathing may be reckoned among the most unfavorable symptoms January 18th 1814 Barton on the phthisis pulmonalis or pulmonary consumption. a disease attended with great Emaciation & hectic fever cough and purulent expec- toration the disease comes on gradually with blue colour of the cheeks yellow colour of the tunica adnata dyspnoea particularly when employed in mount- ain ascent a sensation of stricture of the breast a discharge from the lungs of pus mixed with blood the patient experiencing pain on lying on the side. The blood drawn in this disease exhibits the buffy coat so distinguishable in the phlegmasia the strength gradually declines the hectic fever does not long continue before debilitating sweats comes on particularly in the evening the urine high colour- ed with a branny sediment a continual di- latation of the pupils is an attendant of this disease the face pale in this disease but [crossed out] during the exacerbations a florid red and an almost circumscribed spot appears on each cheek. In the early part of the disease the pa- tient is generally of a costive habit but to- ward the latter part of the disease it is at- tended with constant diarrhea. an An ulcer of the lungs is one of the most frequent causes of this disease although hae- moptisis may terminate in this disease but it frequently occurs and terminates fa- vorably particularly in those that have not a predisposition to the disease Tubercles are reckoned among the most frequent causes of this disease ulceration is sometimes the consequence of the rupture of vessels in the substance of the lungs after pus is formed the patient is affected with cold shiverings the cough continues the same sometimes the matter is discharged into the cavity of the thorax constituting Empyema sometimes when the disease depends upon a vomica it terminates favorably the vomica bursting and the matter discharged by the mouth by this we see that the recovery from vomica is by no means rare inflammation of the liver some- times causes this disease owing to the sympathy existing between those parts or adhesions forming betwixt the liver and diaphragm the matter dis- charged into the cavity of the thorax causes or produces this disease a long existing sy- philis may produce all the phenomena of the true phthisis pulmonalis even in those that are not predisposed to it Flax dressers stone cutters and Millers are liable to pulmonary complaints pertus- sis or Whooping cough may be considered a frequent cause of this disease Barton considers it a difficult question to decide whether this disease is infectious or not Many respectable authors assert that a predisposition to this disease may be it is contagious [crossed out] discovered by an acute sensibility frequent haemorrhages from the nose in early life a slender habit with long neck Superficial blue veins frequent hoarseness on exposure to cold. phthisis pulmonalis may be considered a disease incident to northern climes very few cases occurring in the southern states Treatment &c this may be considered one of the most dif- ficult diseases we have to deal with if any disease may be considered incurable it is phthisis pulmonalis this disease requires very different methods of treatment it is our duty to watch with attention the approach of this disease and prevent it from gaining ground or it will inevita- bly prove mortal we should not consider our patient safe as long as there is a vestige of pain or any of the symptoms remaining as catarrh may be considered a frequent remote cause of this disease it should always be attended to especially in those who have a predisposition to phthisis pulmonalis and the proper methods of treat ment should be rigorously observed. Opiates Anthiphogistic regimen &c. When the disease arises from catarrh the diet and employment of the necessary exercise change of climate &c. should be attended to Mercurials employed with a view to excite salivation is sometimes considered of service Barton says he can say nothing in favor of mercury from his own experience I have found it of less service than Ipecacuanha low diet and the vitriolic acid Barton considers Mercury as deserving of a trial Arsenic [crossed out] in the min- eral solution given in the dose of 4 or 5 drops 3 or 4 times a day this medicine useful in solving tubercles an abstemious diet is recommended in all cases Much has been said of the advantages attending a free use of milk in the incip- ient phthisis pulmonlais the prejudices in favor of asses milk like a great mem- ber more of our prejudices is without foundation. Milk is in many cases too nutritious a diet to be employed unless sufficiently diluted or in the form of run- net whey slight bloodletting by leeches Digitalis is recommended by some authors It may always be found useful by les- sening arterial action and serve as an auxiliary for the lancet blisters will always be found remedies of the first importance by averting the progress of the disease the discharge to be kept up by cabbage leaf the blisters to be applied over the cavity of the thorax it is on all hands agreed that the antimonials are not calculated for this disease the vitriolic so- lution of great utility in all cases of pthisis pulmonalis of all the Emetics Ipecacuanha is among the most important I have been in the habit of using sacca rum saturni in haemoptises and I be- lieve I have reaped advantage from it tar water of benefit in alleviating pain January 20 1815 Barton on the Scrophula or king’s evil tumors or swellings of the conglobate glands particularly of the neck and also swellings of the upper lip always indicate a serophulous habit it seems to be the prevailing opinion that this disease arises from languor of the ab- sorbent system and from which arises the swell ling of the upper lip and under the eyes a proof now well established is that this disease is not contagious and from its disagreeable nature is certainly a consolation as this disease evidently arises from a weak- ness and flaccidity of the system among the first remedies for this disease we should place that large assortment of medicines called tonics or robo- rants the bark claims our first attention the native alder given very largely internally and bathing the ulcers with the warm infusion the acids are among the rem- edies of the first importance in this disease Bronchocele or in vulgar language called guitar this disease particularly affects us about the age of Puberty it is an affective of the thyroid gland it is generally noticed by a thickening of the parts this disease is peculiarly incident to the western parts of the union particularly the parts con- tiguous to the lakes in South America it is extremely common common particularly in moist tracts of Country it has been generally supposed to be an endemic in those tracts of country in which the water is impregnated with a calca- reous matter this disease has been ascribed by some writers to the frequent use of snow water this hypothesis at first view appears plausible owing to the disease be- ing so frequent in the alpine Countries of Europe where the mountains are covered with external snows. Women are infinitely more subject to this disease than men. January 23 1815 Barton on the rachets or rickets this disease may be supposed to arise from a deficiency of the earthly matter in bones in the treatment of this disease is attended with great dif- faculty if suffered to run on too long the first remedies in this disease is that large assortment of medicines called tonics this class can be used with the greatest advantage the cold bath can be employed with the greatest advantage as a preventative the total exemption of our Indians from this disease is to be ascribed to their frequent use of the Cold bath The Peruvian bark has acquired great reputation in this disease among the rest of our remedies for this disease we must not omit mentioning the salix alba as a substitute for the Peruvian bark or bathing in a strong decoction of the salix alba with water is considered an excellent remedy the various preparations of Iron are considered of importance in this disease blisters have been too little employed in this disease to be applied in the beginning of the disease Cathartics and di- uretics have been employed with various success in this disease January 23 1815 Barton on dysentery this disease in the Nosology should be placed immediately after the fevers and Exanthemata this the same causes which produce this disease produces the fevers A contagious disease attended with fever tenesmus and fre- quent going to stool with a discharge of mucus sometimes mixed with blood when mucus alone it consti tutes the dysenteria alba or what may be called the true catarrh of the intestines sometimes the disease comes on with the ordinary symptoms of intermittent fever. sometimes the dis- ease comes on with a diarrhea it is attended with loss of appetite the patient not unfrequently throws up a quanti- biliary Matter it is generally attend -ed with fever of the intermittent kind But sometimes of the typhoid form the fever very when the fever attending this disease is of the inflammatory kind and is not treated with suitable remedies a gangrene rapidly comes on the matter voided is of a foetid smell when the natural faeces appear owing to the operation of Cathartics or some other means they are in the form of Scybala when these scybala have been voided it procures a remissi- on of the symptoms one symptom of this disease which we must not omit mentioning is that when any thing has been swallowed the patient feels an immediate in- clination to go to stool as if the food had passed immediately through the intestines this is owing to the very irritable state of the intes- tines the d causes of dysentery differ very little from that of fevers and in enumerating the causes of one disease you do of the other wise. marsh Miasmata Idio Miasmata and the like by in attention to cleanliness this disease may be rendered highly Destructive Barton contrary to the greater number of Writers pre tends to deny that this disease is con tagious I believe the proximate of dysen tery is a preternatural constriction – of the colon Dysentery is sometimes entirely a local disease but this in general is not the case some have considered obstruc- tion of perspiration as a proximate cause in the dissections of bodies who have died of this disease the diameter of the vessels of the liver are uniform- ly increased and abscesses are often found in this important organ Treatment perhaps no disease requires such a variety of remedies as this one but when it is complicated as it often is with all the symptoms of inflammatory fever venesection is not to be deferred In general the primary indication for the cure of this disease is that class of remedies called Cathartics and those of the most benefit are the Oleum ricini flowers of sulfur Calomel Another very useful Cathartic in this disease is the vitriolic solution of those by Enemata or glysters of various kinds of singular benefit in this dis- ease Emetics are another class of rem- edies not to be dispensed with in the treatment of this disease Ipecacuanha In whatever way this medicine op- erates it is certainly of the first importance to be given in combination with a small quantity of opium this to be given in the Dysenteria Cruentes Or that variety attended with a discharge of blood Opium in this disease is of considerable benefit I know not of a single case in which I had to re- gret the free use of opium the patient previously to be evacuated by Cathartics Practitioners have found considerable benefit resulting from the free use of blisters to be applied over the abdomen a slight salivation by mercury is sometimes of utility the Mercury to be given with caution sometimes the Exhibition of Mer- cury brings on a mortal haemorrhagy from the intestines if it does not show its good effects in a short time its Exhibition to be discontinued when the pyrexia attention & this disease assumes the typhoid form Cathartics to be adminis- tered with caution owing to the debility which they produce anodyne and cor- dial Medicines in this case are to be resorted to James After Dysentary the next medicine that claims our attention disease that comes under consideration is diarrhea attended with frequent stools and sometimes with pyrexia there are several varieties of this disease vvs. diarrhea Mucosa Diarrhoea biliosa besides more too tedious to mention the same causes which produce dysentery may also produce this disease Treatment when the pulse is [crossed out] frequent bleeding is to be resorted to with advantage among the remedies in this disease we must not omit mentioning Astringents the of which class the most important is the terra japonica or kino a decoction of galls ½ oz of the best galls to a pint of water brandy 2 gill to be added Emetics are sometimes found of infinite advantage Absorbents are sometimes useful auxilia ry medicines in this disease such as the Magnesia lime water the operation of those medicines are to counteract acidity prevailing in the intestines What I have said of the use of blisters in the dysentery is also app- licable to diarrhoea January 26th 1814 Barton on Cholera Morbus This disease is attended with vomiting and purging of bilious matter it is truly a febrile disease in United States it is almost entirely to the summer season the disease for the most part makes its attack suddenly the patient suddenly attacked with violent vom- iting and purging at first the pulse is full and strong but soon becomes low the patient debilitated Treatment the most success- ful practice consists in giving mild tepid drinks viz. weak chicken broth warm water &c. After the intestines has been washed out Opium is to be given Enemata an infusion of linseed is found of ben- efit in some cases we must have immediate recourse to opium at other times stimulants are to be resorted to such as sinapisms in ma- ny cases of Cholera Morbus the warm bath is to be employed in no disease are stimulants called for work more energy if the patient be of a full habit and the pulse strong we are to employ the lancet this will sometimes restr- ain vomiting in the intermittent Cholera Morbus bark is to be employed another variety of this disease which is called Cholera Infantum and which is confined to Infants differs but little in its symptoms and in the treatment from Cholera Morbus the principal symptoms are preternat ural heat of the head attended with de- lirium and sometimes mania which is manifested in some instances by the child attempting to bite the nurse in the cure of this disease mild tepid drinks are to be employed when the stools are very foetid mild cathartics and the early ad- Acetate of lead given to the extent of 2oz 3gr in a day ministration of opium will be found of ben- efit application of brandy to the abdomen the warm bath stringents &c. are of great benefit January 27th 1814 Barton on dropsy by dropsy we mean an effusion of serous fluid into the different cavities of the body a disease for the most part attended with fever and of which there are several varieties the first of which is Hydroce- phalus. or dropsy of the brain Hydrothorax or dropsy of the Chest Ascites or dropsy of the Abdomen Hydrocele or dropsy of the testicle and Anasarca or dropsy of the Cellular Membrane. The first of which I shall treat of is Hydrocephalus or attended with a swelling of the head a collection of water principally in the ventricles fever pains of the head dilatation of the pupil the patient drowsy the appetite impaired the pulse in the early stage does not appear much altered the face flushed par- ticularly one side February 14 1815 Barton on haemorrhagies a disease attended with pyrexia and profuse discharge of blood of which there are several species the of which I shall mention is Epistaxis or bleeding from the nose this disease in children may be supposed to arise from pleth ora of the arterial system in old peo ple it may arise from a contrary cause this disease in general an- nounces itself by the following symp toms throbbing pains of the head flushings of the face the belly is almost universally costive the next bleeding I shall mention is haemoptysis attended with [crossed out] difficult breathing and cough the haemoptysis often succeed Epistaxis when this has ceased to recur this disease may be considered hereditary it generally comes on with a pain of the thorax great heat of the chest flushings of the face &c. announce the approach of a discharge of blood from the lungs the next species of haemorrhagy I shall mention and certainly one of the most dis- tressing is haemorrhoids or piles the first symptoms of this disease is pain about the loins and anus and attended with discharge of blood and sometimes mucus from the rectum besides those already enumerated is Hematuria or discharge of blood from the urinary organs Haemata- mesis or discharge of blood from the stomach this sometimes may arise from blood sent by the liver through ductus communis into the duodenum and discharged by the oesophagus Melaena or a discharge of bloody matter of the consistence of Molasses from the stomach or intestines In the Treatment of haemorrhage blisters and setons are of the first importance in haemorrhagies purges are next to be reckoned remedies of the least importance in this disease Allum Combined with Opium is of the considerable benefit The neutral salts nitre &c. is of considerable efficacy I should suppose Antimony to be of service in uterine haemorrhagy from the great benefit derived from its use in dysentery Ipecacuanha is considered by some writers as an reme- dy of absolute specific in this disease the med.. to be given to the extent of 1 In haemorrhoides the opium is not to be employed owing to its constipating qualities the saccharum saturna given to the extent of 5 6 or 7 gr is a remedy of singular benefit in Epistaxis as well haemoptisis and uterine haemorrhagy I have found it of importance to combine with it a small portion of Ipecacuanha applications of cold is sometimes of Eminent service Barton is great he is good and wise In him America’s richest prize He teaches us full of times to save our fellow creatures from an untimely grave He teaches us ‘gainst sickness to guard Surely he deserves the heaven’s richest reward Februa 19 1815 Barton on the Neuroses or order of spasms the first disease I shall treat of under this head is tetanus of which authors mention four different species Opisthotonos Emprosthotonos this seldom occur- -ring Pleurothrotonos and trismus or locked jaw tetanus is generally attended with universal rigidity of the muscles tetanus may arise from different causes wounds verminose affections Cold appli ed when the body is overheated also tetanus Arthritieus or the disease arising from retro- cedent gout generally tetanus may be defin’d a disease affecting the muscles the de- velopement of which is gradual the intellect in general is but little impaired the bowels for the most part obstinately constipated the dis ease is divided into two different varieties the tetanus symptomaticus and the tetanus Idiopathicus the former arising from wounds Cold &c. tetanus often comes on after a wound has healed favorably tetanus may arise from the bite of different venomous serpents in the treatment of this disease Opium is the first Medicine that claims our [crossed out] [illegible] attention This is certainly one the most im- portant remedies employed in this dis ease it should be given on the first appearance of the disease in small and frequent doses some authors rec- ommend the Exhibition in the liquid form frictions with laudanum is also found beneficial in the employment of opium in tetanus it should not only be given largely by the mouth but also in the form of Enema a tincture formed of the seed of the datura stramonium is sometimes found of singular ben- efit a decoction of tobacco in the form of an injection is recommended in re- curring to the use of this article It should be employed with great caution musk is recommended by some authors allied to those articles are those stimulant remedies Aether wine vitriolic acid the bark is recommended recommended by some authors it is certainly ben- eficial in the tetanus complicated with intermittent fever an Electuary formed of Mustard is of eminent service given in large doses it is proper that I should say something concerning the use of Mercury Dr Barton admits of the propriety of giving it Calomel to purge he mentions this as a preventative after wounds it must be given to excite the Mercurial flow Dr Barton mentions a case that he cured after coming on by Mer- cury he says upon the whole it is an efficacious remedy the cold bath may sometimes be resorted to with children in the convulsions this remedy to be employed with great caution the warm bath is highly recommended by most writers it is certainly not so dan- gerous as the cold bath. Barton mentions a case that he which he cured by bleeding he says he is far from considering there is any inflammatory ten- dency in this disease trismus has been known to disappear on the appearance of the hae- morrhoidal flux as the bowels are obstinately costive mild and in some cases drastic purgatives are to be employed Dr Barton mentions a case that he cured by cathartics Calomel and jalap this shows the antispasmodic power of Cathartics February 23rd 1815 I go on to speak of other diseases near- by allied to tetanus the first of which I shall mention is Epilepsy this and convulsions is so nearly allied that the treatment is nearly the same in this disease there is a violent convulsion of the muscles followed by sleep this disease a- rises from various causes Ep- ilepsy differs from convulsions in some respects Epilepsy may cer- tainly be classed among the her- editary diseases Epilepsy may be brought on by terror pressure of the brain also produces it I go on to speak of the remedies employed in Epilepsy physicians have been much divided concerning the propriety of bloodletting the prudent practitioner will have recourse to bloodletting but it should not be employed largely blisters and sinapisms are of Eminent service in the periodical Epilepsy purges are always to be employed particularly when the disease arises in Children from worms an Emetic given an hour before the accession of the expected but will sometimes be of benefit Theoretically viewing the subject one should expect benefit from the free the free use of foxglove when the dis- ease arises from plethora the opium is a remedy not to be omitted in the treatment of this disease and [illegible] all others it is certainly the one to be most relied on the powdered seed of the Datura stramonium given in the dose of 6 grains twice in 24 hours will be found an all important remedy the external application of tobacco to the scrobiculus cordis bark combined with the Chalybeates is a remedy of no mean value the root of the wild valerian employed in decoction Infusion Extract and the powder the powder is the most general way of giving the dose is to be increased according to circumstances from 1 to 2 or 3z when given in the form of powder to be combined with bark Among the Metallic remedies in this disease the most important is the cuprum ammoniacum this being a powerful medicine it should be begun in small doses from 1/4 1/6 or 1/8 of a grain if it creates nausea it should be combined with ginger Epilepsy has been cured by salli- vation brought on by Mercury this to be employed with caution until it brings on ardor urina a solution of white vitriol and sugar of lead will be found an excellent injection if not sufficiently irrita- ting it should combined with Corrosive Sublimate I now proceed to the consideration of Chancre the first observation is those with short prepuces are not so liable to chancre in men the fraenum prepuce and glans is the most frequent seat of the disease in Woman the vagina and labia of the chancre germs on the glans or prepuce the inflam- mation runs high When the chancre is seated at the angle of the fraenum of it should not be destroyed it should be divided by the knife to prevent matter from being confin’d phymosis and paraphymosis is consequences of Chancre Mercury is certainly a specific in the cure of chancre the chancre may also be cured by re- moving it with the knife or the caustic the best is to avail ourselves both of local and general remedies application of lunar caustic is preferable to excision after the first sloughs off the application to be Renewed among the local applica- tions the Mercurial ointments are the best they quickly create a new action of the parts lotions of blue and white vitriol are the best of there is a tendency to inflamma tion rid precipitate should be sprin- kled over the chancre the blue pill will be found an excellent substitute for the Calomel of this should not agree with the stomach and the intestines you may also make use of frictions on the inside of the thigh this will expedite salivation there is no test of the operation of mercury except it produces sallivation March the 3d 1815 Dorsey on the Buboe Buboes are swellings of the lymphatic glands and are a consequence of the Venereal poison buboes begin with a pain and small tumor in the groin the color of the skin remarkably florid in the cure resolution if possible must be effected the most favorable way of administering the Mercury is to rub it on the inside of the thigh all the remedies for inflammation are to be employed leeches are to be applied to the tumor but in spite of every exertion sometimes suppuration will be the result if this should be the case a small open- ing should be made with a lancet and the caustic should be applied to destroy the skin and make the opening large repeated application of blisters and the antiphlogistic plan followed up will sometimes occasion the absorption of the pus if the con stitution suffers bark should be employ ed there is a scrofulous habit 1/8 of a grain of the corrosive sublimate and 8 grains of cicuta given 3 times a day will be found beneficial Indent Jan This indenture made this tenth day of July AD 1815 between Joseph Griffith of Charlestown Township Chester George Weaver JH Thomas Sam Nixon George Weaver this will I Favourite of Joseph if thing then Lewis Gloria thing things thing things things tings things things J Joseph Griffith things things Sam Nixon thing things things things In the Lues venerea the tonsils are first found inflamed and ulcers form on the fauces in order its dis- criminate betwixt the venereal and common sore throat or the exructation of coagulable lymph on the fauces in the you must observe in the former the ulcers have the appearance of being scooped out right of the substance sometimes Lues comes out in blotches on the skin the mercury to be exhibited as in the chancre sometimes the blotches produce ulcers the red precipitate is then to be sprinkled over them the diet need not be restricted The same treatment as in the first stage is to be follow- ed up in the second In nodes no local treatment is neces- sary the general treatment will suffice Dorsey Dorsey [illegible] [illegible] [illegible] [illegible] B Barton James Griffith Joseph Griffith Joseph Griffith James Stephen Ellis Ellis Lewis N W Mixer Jos Stephen Burson [illegible] Ellis Lewis MD Book March the 29th 1815 Med. Hist. MS. B 85 [illegible] 4444 8888 [illegible]