A-A%:^A/A;iAA'A m^ ?h *$$®m^AAA ■■,: m< «&&** It-®-- llfi; IL-j;iwa!K:!>Aft;il!.!i!;.iril ARMED FORCES MEDICAL LIBRARY Washington, D. C. / VIEW OF THE NERVOUS TEMPERAMENT j BEING A PRACTICAL INQUIRY INTO THE INCREAS- ING PREVALENCE, PREVENTION, AND TREATMENT OF THOSE DISEASE'S COMMONLY CALLED NERVOUS, BILIOUS, STOMACH y LIVER COMPLAINTS; IJVJDIGES? .'J.Y; LOW SPIRITS, GOUT, iSc. BY THOMAS TROTTER, M. D. Late Physician to His Majesty's fleet under the com- mand of Admiral Earl Howe, k. g. ; and to the squa- drons commanded by Admiral Lord Brid- port, k. b. Admiral Earl St. Vincent, k. b. and the Hon. Admiral Cornwallis ; Member of the Royal Medical Society of Edinburgh ; an Honorary Member of the Royal Physical Soci- ety of Edinburgh, of the Medical Society of Aberdeen; and formerly Physician to the Royal Hospital at Haslar, Sec. Sec. Boundless intem/ierance In nature is a tyranny : it hathjbe~?n ., The untimely emptying of th^'/tapfCy throne, And fall of many kings. A■'' Shakespeare. TROY, K.Y+lJftfSrp PUBLISHED BY WRIGHT, GOODENOW, Sc STOCKWELLj AND FOR SALE AT THE RENSSELAER BOOK- STORE, Sc AT THEIR STORE IN BOSTON. 1808. DEDICATION. TO JAMES GREGORY, M. D. PROFESSOR OF THE PRACTICE OF MEDICINE 1U THE UNIVERSITY OF EDINBURGH, &C. &C. MY DEAR SIR, IN requesting the sanction of your name to the present work, with honest pride I acknow- ledge the many and great obligations you have conferred on the profession of medicine by your estimable talents ; but still more, by the manly spirit and dignified independence with which, on all occasions, you have defended its rights, and maintained its honours. At a time when avarice is making rapid advances to nar- row its benevolence, and a servile compliance with the frivolous forms of fashionable life is degrading its duties, it must be grateful to every generous mind, to behold a nobler exam- ^ ^ $ ^ ^ IV DEDICATION. pie from the practical chair of the University ' of Edinburgh. And should any merit be due to the following pages, it will be derived from the humble imitation of your zeal, integrity, and candour. Mankind have seldom been delighted with a picture of their infirmities; and the physician who warns his fellow mor- tals how to evade them, is liable to be consi- dered rather as an officious adviser, than a welcome monitor. But if it is true, as I have said, that nervous diseases make up two- thirds of the whole with which civilized soci- ety is infested, and are tending fast to abridge the physical strength and mental capacities of the human race, it must be the duty of some person to sound the alarm, and to announce the danger, however unprofitable the task. The work which I have now the honour to lay before the public, was written eighteen months ago : and though several authors have appeared on the same subject, since that time, I do not find my labours anticipated. The ground which I have taken in the discussion, is in many respects new. This View of the Nervous Temperament may therefore be con- sidered as the result of a more extensive field DEDICATION. V for experience, than generally falls to the lot of every physician ; for it has been acquired by attendance on some thousands of cases, in both sexes, under all the varieties of rank, employment, age, situation, climate, &c. I well remember, when I was young ia the profession, no diseases puzzled me so much as those of the nervous kind. I was every day committing blunders : in vain I had recourse to books, for books could not supply the deficiency, and I was frequently mortified with seeing my patients get worse under my treatment. Time, and much expe- rience, only, were capable of correcting my errours. What first gave my practice corsis- tency, was the careful study of the ner\ ous temperament; to mart: what were its original peculiarities; what its1* propensities ; *i,d by what causes its diseases /ere drawn forth. I am rather apt to believe, that most young men, in beginning their nodical caieer, run great hazard of mistak'n g thesr complaints ; as they only become apparent by a concourse of symptoms, that is exrremely irreguV.r and equivocal. An 1 I have know> more than one instance of nervous females having been VI DEDICATION. treated for typhus fever, to the great alarm of their families, when they were labouring un- der debility of body and mind, widely diffe- rent in nature ; and attended too by men who called themselves seniors in the practice. A prevailing contagion must be badly under- stood, when both physician and patient be- come dupes of such unnecessary fears. I am, therefore, in hopes that the method which I have taken in the following investigation, will somewhat contribute to familiarize the junior members of the profession with the genius of nervous disorders, and to guard them against mistakes in the treatment. But I have no hesitation in thinking, that my enquiry may be useful to general readers. We meet with numbers of persons in the world, who, though obstinate in refusing ad- vice for their own health, are nevertheless ve- ry ready to comply with every precept that may correct the hereditary predisposition to disease in their offspring. Much of my ani- madversions on these disorders, is with a view to the prevention ; and if parents and guardians will only Interest themselves in the business, my trouble cannot be in vain. It is DEDICATION. VII indeed a task, in the present stage of society, that well deserves the attention of every friend of his fellow-creatures, and his country. Great Britain has outstripped rival states in "her commercial greatness: let us therefore endeavour to preserve that ascendancy, which is so essential to our welfare in the convulsed condition of Europe, by the only means that can do it effectually. That is, by recurring to simplicity of living and manners, so as to check the increasing prevalence of nervous disorders; which, if not restrained soon, must inevitably sap our physical strength of constitution ; make us an easy conquest to our invaders ; and ultimately convert us into a nation of slaves and idiots. It has been customary with writers on these diseases, to illustrate their subject with the anatomy and physiology of the parts con- cerned. But I see no necessity for this in the present inquiry ; and my sheets have un- expectedly swelled to a size that precludes the introduction of such matter. I must therefore refer my young readers to Dr. Whytt on nervous disorders, and to the valu- able volume of Dr. Saunders on the liver, yiii DEDICATION. 4 for what they may not find explained in com- mon elementary treatises of anatomy and phy- siology. My plan is briefly this : a cursory view is given of the health of the savage state, in or- der that the contrast with civilized mankind may appear more striking. The inhabitants of a large town are next described ; which may be construed into a kind of medical anal- ysis of society; and this leads to an account of the remote causes, as found among refined modes of life and luxurious habits. A chap- ter follows on the influence which these disor- ders have on national character and domestick happiness. The history and progress of ner- vous diseases, with a general doctrine, or summary of the pathology, precede the pre-* vention and method of treatment. On the whole, there will be found little of what is called theor)', in this discussion : un- shackled by any attachment to system, and unseduced by the love of novelty, I have en- deavored to delineate the Nervous Tempera- ment, as I have seen it in actual practice, and in a large intercourse with mankind. But in treating of a class of diseases out of the usual DEDICATION. IX tract of enquiry, I am willing to confess, that many peculiarities may be-observed, and some obscurities detected. I will make no apolo- gies to my countrymen, for offering them my advice, on matters that so nearly concern their health : if the title of my book excites dislike, let them remember the perusal of it is volun- tary. Nor will I insult their discernment, by any fulsome justification of my own motives and disinterestedness. If I have acted the part of an honest man, that must answer for itself. But, sir, should you recognize any thing in these labors worthy of the medical school of Edinburgh, I shall be greatly overpaid. And as this may be the last time I shall appear be- fore the publick, as an author, gratitude com- pels me to thank the profession, both in this country and on the continent, for the kind re- ception of my former studies, and the nume- rous testimonies given in their favour. I remain, my dear sir, With the utmost regard, Your most faithful humble servant, T. TROTTER. Newcastle on Tyne, > Nov. 8, 1806. > INTRODUCTION. THE last century has been remarkable for the increase of a class of diseases, but little known in former times, and what had slightly engaged the study of physicians prior to that period. They have been designated in common language, by the terms, nervous, spasmodick, bilious, indigestion, stomach com- plaints, low spirits, vapours, Esfc. A gencrick definition of them, from their protean shape and multiform appearance, is almost imprac- ticable. They vary in every constitution j and assume, in the same person, at different times of life, an inconstant assemblage of symptoms. ^ In another work, when cursorily treating of these diseases, I have attempted to give a general character of them, and for want of a XII INTRODUCTION. better, I shall insert it here. " Nervous feel- " ings, nervous affections, or weak nerves, ** tho' scarcely to be resolved into technical " language1, or reduced to a generick defini- " tion, are in the present day terms much " employed by medical people, as well as " patients ; because the expression is known c* to comprehend what cannot be so well ex- " plained. An inaptitude to muscular action, " or some pain in exerting it; an irksome- " ness, or dislike to attend to business and " the common affairs of life ; a selfish desire " of engrossing the sympathy and attention " of others to the narration of their own suf- " ferings ; with fickleness and unsteadiness " of temper, even to irrascibility ; and ac- " companied more or less with dyspeptick " symptoms, are the leading characteristicks " of nervous disorders ; to be referred in ge- " neral, to debility, increased sensibility, or "■-torpor of the alimentary canal."* In the present day, this class of diseases forms by far the largest proportion of the whole, which come under the treatment of * Medicina Xcutica, vol. 3, Spasmodic^ Affections. INTRODUCTION. Xlll the physician. Sydenham, at the conclusion of the seventeenth century, computed fevers to constitute two-thirds of the diseases of mankind. But, at the beginning of the nine- teenth century, we do not hesitate to affirm, that nervous disorders have now taken the place of fevers, and may be justly reckoned two thirds of the whole, with which civilized society is afflicted. Dr. Cheyne, who wrote about 'the year 1733, in his work entitled the u English Malady," makes nervous disorders almost one third of the complaints of people of condition in England : from which we are led to believe they were then little known among the inferiour orders. But from caus- es, to be hereafter investigated, we shall find that nervous ailments are no longer confined to the better ranks in life, but rapidly extend- ing to the poorer classes. In this neighbour- hood, as far as I am able to judge from my own experience, they are by no means limited to the rich : and it affords a melanch -ly pic- ture of the health of the community, to ob- serve this proportion so very large. It is probable the other countries of Europe do not exhibit such general examples of these Xiy INTRODUCTION. diseases ; as many of their causes are to be traced to the peculiar situation of Britain ; its insular varieties of climate and atmosphere ; its political institutions and free government; and above every thing, its vast wealth, so diffused among all ranks of people. VIEW OF THE NERVOUS TEMPERAMENT, &c. &c. &c. CHAPTER I. The health of the savage state compared with modern times. THE savage and civilized states of man, as may be observed in the earliest ac- counts of history, have been marked by phy- sical traits of character, as well as moral: and though his diseases and his vices may be smaller in number in the one condition than in the other, they have nevertheless exhibited signs and dispositions peculiar to themselves. 16 Our rude ancestors, born and brought up in a hut or a hovel, almost naked from infancy to manhood, and constantly exposed to th* weather, whether employed in agriculture, tending herds and flocks, or the more labori- ous pursuits of hunting and fishing, had few bodily disorders. Death, under such modes of living, is to be considered as the decay of nature : some may fall by war, and a few by accidents ; but none are brought to the grave by excess or debauch. It is notorious that all the savage tribes of the new continent, when compared with European manners, are ob- served to be chaste, temperate, and abstemi- ous.* Tacitus, speaking of the manners of the Germans in his days, describes the convi- vial assemblies of that people, where drinking fermented liquors was carried to the most fe- rocious degree of ebriety ; but no where does he mention their diseases as having sprung from this cause. The favourite beverage among them was beer, which, when duly pre- pared, is a wholesome drink. But their man- ner of living must in a great measure have * The inhabitants of some of the South Sea isl- ands are examples to the contrary. 17 counteracted the effects of intoxication : such as the robust exercises, and their simple food, " consisting of wild apples, fresh venison, curds, and cream," and the like, none of M'hich were calculated to oppress the stomach and hurt digestion, as we observe among full livers in modern times. Indeed it is to be remarked every where, how much longer the laborious porter and drayman, who get often, drunk, will continue their career, than the less exercised gentleman : a proof that labour, by invigorating and hardening the body, makes it resist even the effects of debauch. How soon would the morning dram of a Billings- gate fish-wife destroy one of our high bred women of fashion I The virtue of chastity was-general among the Germans : matrimony, it is said, was se- verely kept; and the mixture of the sexes, before the body was full grown, was strictly prevented. Here was one of the strongest securities of health ; a3 a contrary practice in this age, i3 one of the great causes of bodily decay. We are also told, that the large limbs and muscular form of the parents, were ex- pressed in the shape of the children. Anc* B2 13 ther proof of bodily health was, that every mother was able to nurse her own child ; the opposite to this parental office, is one of the lamentable failings of modern constitutions. It was part of the matrimonial contract, for the wife to share with the husband his labours and dangers ; and to be his companion in peace and war. This custom, of course, pre- vented all the evils of a sedentary life. In a country that held the marriage vow so sacred, adultery was seldom found ; and it was consi- dered in so heinous a light, that neither beauty nor wealth could ever find the adulteress ano- ther spouse. Such was the healthful system of manners practised in the woods of Germa- ny, which were the cradle of those laws that now govern this land of freedom. The feudal system which succeeded to the age which Tacitus describes, and which spread over Europe, v/as highly favourable to vigour of body, and by consequence to health. The women were then accustomed to attend their husbands to the field, and to remain in sight of the battle ; not only with a view to load them with praises and caresses at the conclu- sion j but to remind them of the protection 10 due to wives and children. Courage and valour, with such incentives, would become invincible. All the pastimes and tournaments of those days, were only kinds of palaestrae for exercising the body so as to inure it to martial fatigues. The females were constant specta- tors of these tilts and feats, and their presence did not fail to animate the brave ; and it was the province of the fair to reward the victor, and confer the prize on the successful candi- date. Now in the woods of Germany, where mothers of families shared with their hus- bands all the toils and privations of the field, such complaints as bilious and nervous must have been unknown, because all the causes which render them prevalent in this age, did not then exist. They are the progeny of wealth, luxury, indolence, and intemperance, as they now appear. In the eighteenth chapter of Genesis, we meet with some fine proofs of the simplicity of living among the patriarchs, which may be called the earliest stage of civilized society. When Abraham entertained the three angels, in the plains of- Manure, he hastened towel- come them with all the tokens of a kind hos- 20 pitality. Sarah his wife kneaded three mea- sures of fine meal into cakes, and baked them upon the hearth. Abraham himself went to the herd, and fetched a calf, tender and good, and gave it unto a young man to dress it. And he took butter and milk, and the calf which he had dressed, and set it before them, and they did eat: and he stood by under a tree, as if to watch when they wanted any thing. Again, when Lot entertained two an- gels, it is said he made a feast, and baked un- leavened bread. These banquets for angels, so simply detailed in holy writ, would be con- sidered poor fare for the epicures and glut- tons of our times, who dine at a lord mayor's feast, if we are to judge from a list of dain- ties, just published, of one of these entertain- ments. We are farther told in the sacred vo- lume, that Boaz invited Ruth to come at meal time, and eat bread, and dip her morsel in the vinegar With the.reapers ; and he reached her parched corn to eat. Our present labourers in the harvest would be sadly pinched with hunger before they would content themselves with such simple fare. In the Iliad and Odyssey of Homer, we meet every where 2* accounts of the like simplicity of food and manners. When the foreign ambassadours* came to treat with the Roman consul Denta- tus, they found him at his farm dressing tur- nips : a species of amusement and economy that does not enter the budget of British statesmen. Where the earth is thinly peo- pled, and when commerce has made no pro- gress, mankind live chiefly in families ; and their habits and employments uniformly incul- cate temperance and sobriety. Society and population must be far advanced, before luxu- rious living, and vicious customs, attain such growth as to enervate the human frame. The nervous system, that organ of sensa- tion, amidst the untutored and illiterate inha- bitants of a forest, could receive none of those fine impressions, which, however they may polish the mind and enlarge its capacities, ne- ver fail to induce a delicacy of feeling, that disposes alike to more accute pain, as to more exquisite pleasure. The timid dispositions are apt to increase in proportion to delicacy of feeling and debility of frame. We see the truth of this fully exemplified, as we recede from the country to the town ; from the occu- 2i pntion of the husbandman and farmer, to that of the artisan and manufacturer; and from the rustick, exposed to all the vicissitudes of weather and season, to the recluse life of the citizen. The physician of a cultivated under- standing, who knows how to appreciate the resources of his art, in approaching the sick bed of any of these persons,would endeavour to investigate the marks and dispositions of body and mind, that give the peculiar cast of character to each, before he would attempt to prescribe for their diseases. He would not confound the complaint of the slim soft-fibred man-milliner, with that of the firm and brawny ploughman ; nor would he mistake the ner- vous cramp of the delicate lady, for the in- flammatory pleurisy of a nut-brown country girl. If both expressed pain on the same spot or organ, he would, in consideration of o- riginal temperament, along with the concourse of symptoms, resolve into first principles what belonged to each constitution ; and thus ana- lyze the morbid phenomena, so as to give a degree of certainty to his indications of cure, and a decision to his practice, that would insure success, if the. disease was at all remediable. 23 As the human being, in a state of progres- sive improvement and civilization, quits his earthern-floored, straw-clad cottage, on the skirts of the forest, or a creek of the ocean, where his time had been spent in hunting and fishing, for the town, where he is to turn him- self to trade and manufacture, he necessarily undergoes a prodigious change of circumstan- ces. He forsakes a' mode of life that had been presented to him by nature ; and in adopting a new situation he becomes the crea- ture of art. When occupied in hunting and Ashing for support, exposure to the external air in winter and summer, gradually endued him with such hardihood and torpor, as to make him proof against the extremes of either cold or beat. His diet, well suited for the purposes of nourishment, was sufficiently pa- latable, without any of those adventitious lux- uries which cookery supplies. His blood and juices were not, therefore, inflamed or vitiated "by highly seasoned dainties j and his sentient system, while it was fully excited for all the movements of vital energy, was never raised to excess by inordinate stimulation. By spending so large a portion of the day out of 24 floors, he enjoyed the full benefit of a pure and unpolluted atmosphere. The muscular parts of the body becoming thus firm and flex- ile from constant exercise, all his motions are performed with strength, ease, and agility. His walk is marked by stability, and his run- ning by swiftness. Having few avocations to engage his attention, he soon acquires un- common dexterity in all his gestures and ac- tions. He ascends the mountain and preci- pice, or climbs the tree and rock, with equal safety and speed : the arrow from his bow is discharged with force, and sure of its mark : the dart and the javelin are alike unerring in his hands. He manages his hook and tackle, as well as his skiff, with surprising knowledge and address ; and in the various attitudes of swimming he is accomplished, graceful and unrivalled. Though in his domestick trans- actions, he exemplifies all the relative duties of husband*, father, and son, he seems exempted from the turmoils and cares which these con- nections necessarily bring with them in civil- ized society. The child is early instructed to follow and imitate his parent in the sports and toils of the field, and soon learns to earn his 2J Own subsistence. No painful emotions for his success in a busy world, harass or perplex the minds of the father and mother, for it does not depend on uncertain patronage or capricious friendships. But the young savage considers it a par: of his filial engagements to share his board with his parents, when age and infirmity have unfitted them for labour. His passion for the sex is temperate, because it meets with no refined allurements, from dress, manners or fashion, to inflame it beyond bounds. Tacitus, speaking of the manners of the Germans, says : " They behave them- " selves with the strictest modesty, being de- " bauched with no alluring objects, with no "provocatives in banqueting." Revenge seems the only passion carried to extremes, to be attributed chiefly to a solitary life. When the savage makes love, he is almost sure of a return : he is neither perplexed with doubts nor fears, nor tantalized by false hopes and promises. The damsel of the forest is a stran- ger to those airs and duplicities^" the coquet and the prude, which characterise some of the sisterhood in every great town. Hence the uncivilized being is free from all those mental C 26 disquietudes, as well as bodily ailments, which - are frequently brought on in both sexes by disappointed love, and an ill-requited passion. Thus health and vigour of body, with insensi- bility or passive content of mind, are the inhe- ritance of the untutored savage ; and if his enjoyments are limited, his cares, his pains, and his diseases are also few. If then it is certain that the rude conditions of society furnish mankind with a hardihood of frame that is susceptible of few diseases ; let us examine man in the polished circle of life, occupied by pleasure, or busy in trade and manufacture. His modes of living are la every respect the reverse of the savage state : nis body and mind are enervated by debilita- ting powers, that render him unfit for labour or great privations j and his diseases acquire a more diversified train of phenomena. The husbandman, in point of constitution, may be considered as a medium between the two ex- tremes. By his active occupation, his labour and cxposurWHo the external air, he partakes of the strength of the barbarian ; and a cor- responding tone is given to his'nervous sys- tem : his mind is not debauched by efTemina- ar cy ; while his temperance and moderation se- cure him against the disorders which prevail in fashionable life. But as we pursue our enquiry among the inhabitants of large cities, we shall observe mankind divided into an immense variety of persons ; nil distinct by fortune, by business, and by modes of living ; and again, all these greatly influenced by original constitution and education. Among rusticks, and still more among savages, there is an universal sameness of character. For as the ambition or inge- nuity of man finds out for him new employ- ments ; these, while they draw forth latent ta- lents, call forth also new passions and desires ; so that however much he may be styled the creature of habit, he is in many respects the creator of his own temperament. The Indian, paddling in his canoe j or the Norwegian scul- ling his skiff, remain unchanged in their man- ners ; because they return at night to their ' family, and to intercourse with their kindred. But embark man at an early age in a large ship, such as an East or a West Indiaman, to traverse the deep as a navigator and seaman, and you soon find that he changes to a diffe- 28 rent species of being, and exhibits traits of a profession, of the most singular kind, which differ from all others.* This new occupation, while it distinguishes him from all the world beside, in gesture, manner, and address, be- stows also a new disposition on his morbid state. His diseases, therefore, show a parti- cular genuis and feature, such as are found only among his own class, and which spring from causes peculiar to the sea life, as scur- vy, &c. It has been remarked, by some acute poli- tical arithmeticians', particularly the famous; Gregory King, that the marriages in London and other Q-reat towns, produce fewer children than those in the country. The reasons for' this difference are very obvious ; he gives ex- amples of the fact, and then enumerates the causes, which are the following ;f * Compare the character which I have drawn of the British seaman, in my preliminary discourse, in the first volume of Mcdicina Miutica, with the Indian, in Robertson's or Raynal's History of America ; or with the Bond-street lounger, as pourtrayed in any modern comedy or novel. berkSESttaa,e.0Uti5al C™1"»™> (*« - Cham. 29 1. The more frequent fornications and adulteries. 2. A greater luxury and intemperance. 3. Greater intenseness to business. 4. Unhealthfuiness of the coal smoke. (He ought to have added, impure air, from hot and crowded rooms.) 5. Greater inequality of age between hus- bands and wives. All these causes, beside many others, still hold good in the present times. His first and fifth reasons require some explanation, which can be done best at this part of my work. It will be allowed on all hands, to be the inten- tion of nature, that years nearly equal should be joined in marriage ; and were mankind left to themselves this would be the case. But art and fashion have become dictators to mat- rimony in this venal age. The young man of the present day must begin the world for him- self; and, like a knight errant in romance, must fight his way to a fortune, before he dares to take a wife. It is too often the case, that the sordid parent winks at the son's indis- cretions with the ssx, rather than consent that he should marry the woman he loves, without C2 30 a rich dower. And while, by this growing custom, a certain number of defenceless fe- males are doomed to all the horrours of pros- titution, in order to gratify the passions of the young, and the avarice of the old, it is one grand step to the degeneracy of the species. It is thus the best years of manhood pass away before marriage is thought of: it then be- comes a convenience, more than an equal at- tachment of the parties ; and hence we fre- quently observe a difference of thirty years and upwards, when the lady may be said to be rather the mistress, than the wife of her hus- band. Amidst theee unnatural unions, it is pleasing to mention some exceptions. Many of the old noble families of the nation have, within these few years, married at the prime ©f life. And it is to be remarked, that these marriages have all been noted for happiness and reciprocal affection : the men being all distinguished by worth and sobriety ; as the ladies are by their virtues, accomplishments and beauty. When Gregory King made h't3 observa- tions, about the year 1696, London contained little more than qne half the inhabitants it 31 does at this day. Other great towns through- out the kingdom, have increased in like pro- portion. Now if such effects followed the city and town life in those times, how much greater must they be in the present. Certain it is, the physician of the seventeenth century had not the multitude of nervous cases to treat, which now occupy the profession. It is probable aho, as far as experience goes, that the proportion of marriages, without children, and the number of miscarriages in married life, are greatly increased ; and these are chiefly confined to the town lady, or at least to people of better condition. It was a remark of the sagacious King, that the system of ag-. riculture in his day, was advancing to dimi- nish the number of cottagers ; but to increase the village, and still more the town. If such was the case a hundred years ago, how much more reason must there be now for the obser- vation, when it is notorious, that some over- grown farmers possess capitals of twenty or thirty thousand pounds, and engross lands that formerly supported twenty or thirty fami- lies ? The middling class of countrymen are, by this practice, annihilated, forced to betake 32 themselves to trade, and there is no degree of rank left between the affluent farmer, and his menial servants : thus, ----a bold peasantry, their country's pride, When once destroy'd, can never be supplied, GOLDSMITH. The lying-in state exhibits some of the great disadvantages of refined life. To the delicate well bred woman, it is always attend- ed with danger ; and the diseases which im- mediately follow, even a fortunate delivery, are often fatal. The rude conditions are ex- empted from all these. The nervous system rendered strong and resisting, surmounts the various changes and evolutions of the birth, and subsequent lactation, without being much harassed or weakened in the struggle. Boun- tiful nature unfettered in her operations, and left to herself, easily accomplishes her pur- pose. The robust rustick therefore attends her husband in the field in a few days ; while the genteel lady is stretched on her couch, often a prey to some nervous affection, but always slow in convalescence. 33 Again, the wives of the countryman and savage seldom fail in being mothers of a nu- merous offspring. But sterility, or what is next to it, premature birth, are common evils in towns and cities. Ninety-nine cases of a- bortion, out of the hundred, may be imputed to a relaxed nervous frame ; either from here- ditary debility, an improper education in childhood, or other causes that are known to weaken the nervous system. Does not every woman known how quickly flights and alarms bring on miscarriages ? In a vigorous consti- tution, accompanied with a healthful set of nerves, such causes can do no harm ; but where the sensibility trembles at every breath, the state of pregnancy is attended with con* stant terrour and dread% CHAPTER II. The Medical description of the inhabitants of a town or city ; being an analysis of society. IN order to bring detached facts into a general view, I shall divide the inhabitants of a large town into the following classes, and give a concise history of each, so far as it may be necessary to shew how business, customs,. and manners, influence health. Class 1. Literary men. 2. Men of business. 3. The idle and dissipated. 4. The artificer and manufacturer. 5. Those employed in drudgery. 6. Persons returned from the colonies. 7. The female sex ;• consisting of the higher, middling, and lower orders of women. 1. Literary Men.—The philosopher and man of letters, who devote most of their time to study, must lead a sedentary life. The 35 person who thinks and reflects much, must retire ; and retirement necessarily abstracts from exercise and amusement. To be shut up in a close room, little exposed to a free and pure air out of doors, soon induces a sallow- ness of countenance ; and as want of exercise accompanies this confinement, the muscular power is diminished, the fleshy parts grow soft and flabby, and general debility is the consequence. Few men attached to literary pursuits are active, strong and athletick : as if study was incompatible with bodily exertion, -the gesture of a thoughtful man is always so- lemn ; and his pace and motions are measu- red and uniform when he walks abroad. The posture of the body in a studious man at his desk, is unfavourable to health. The lungs are seldom expanded by full inspiration ; and while the bronchial cells are not duly stimulated by the powerful influx of an oxygenized atmos- phere, the whole pulmonary organs lose their vigour, and the blood that floridity which is ne- cessary for vital energy & agio vvingcomplexion. All the secretions, and their excretories, fall into inaction from want of muscular motion. By little recreation, and no change of objects 3G to relieve the attention, the whole nervous system sinks into listlessness and inactivity* The mind itself, by pursuing one train of thought, and pouring too long over the same subject, becomes torpid to external agents ; and an undue mental exertion seems to sub- tract from the body much of that stimulation which is required for many operations in the animal economy, particularly what belongs to emotion and passion. The powers of diges- tion, with all the viscera subservient to them, partake in a particular manner of this derangement, and grow unequal to their office. The debility and inactivity which take place in the chylopoeitick organs, react on the ner- vous part of the frame ; and the faculties of intellect, as sympathizing in a great degree with all these highly sensible bowels, arc in- fluenced by the general disorder. Hence the numerous instances of dyspepsia, hypochon- driasis, and melancholia, in the literary cha- racter. But it is to be supposed, that all men who possess genius, and those ment;d qualifications which prompt them to literary attainments and pursuits, arc endued by nature with more than 37 tisnal sensibility of nervous system. And there are moral causes to which they are exi- sed beyond others, that may have a large share in the production of their indispositions. The man who studies and writes for his bread often depends on a precarious subsistance ; sometimes the cold charity of an insolent bookseller: a mind of fine feeling, under the pressure of these circumstances, must fre- quently undergo the most poignant sufferings. Such seem to be the chief causes which give a decided character to the predisposition & dis- eases of literary men. To this class properly beloiig all the learned professions ; and all those who cultivate the fine arts, either for a livelihood or amusement. 2. Men of business.—The subjects of this class are very numerous in all our great towns. It includes all those engaged in trade : many of them, no doubt, have much active bodily exercise ; but that part of them confined to the counting-house and shop, cannot be said to enjoy the advantages of air and activity, as requisite for vigour of body. The posture of leaning over a desk, contrancts the motion of the lungs, and impedes the functions of the D 1 38 stomach. These persons are commonly pale and sallow, soft fibred, and of a slender make. Not a few of them behind the counter, ap- proach in external form towards the female constitution j and they seem to borrow from their fair customers an effeminacy of manners, and a smallness of voice, that sometimes make their sex doubtful. Such degeneracies in corporeal structure, cannot fail of engendering a predisposition to diseases of the nervous kind. It is surprising to see and hear with what address and loquacity some of these little beings in London set off their wares ; as if there were a necessity for a vender of si^k and muslins to be soft as the commodity he deals in. You will*perceive them to wheedle the buyers of goods out of their money, by a kind of fascination. Yet it has often been matter of wonder to me, how a lady of spirit can lis- ten to the prattle of these manikins without disgust; more especially when it is consider- ed that they have supplanted the sex, in an employment which is their birth-right, and are devouring that bread which belongs to thousands of poor women, who are thereby consigned to a life of drudgery, if not of wretchedness. 39 But the mar; of business, in this commer- cial age, is not always to be estimated a cor- rect liver : luxury follows hard upon gain* However punctually the ledger may be kept in the fore part of the day, the tavern too often has its share of the evening. The per- son who has any thing to sell, very naturally praises the quality of his goods ; and as he has daily to dispose of the like assortment, he soon acquires a kind of phraseology and elo- quence in making a bargain. This sort of conversation is always enlivened by something to drink ; the vender knows well how liquor dilates the heart, so that if he can persuade his customer to drink a bottle of wine, he is almost sure of getting his price . This is what makes the trading towns so full of taverns : hence those frequent instances of nervous and bilious complaints which follow habitual ine- briation, to be daily met with in medical prac- tice. Mankind when in pursuit of money, do not give themselves much trouble about intellec- tual attainments. The man of business, how- ever fortunate he may have been in the acqui- sition of wealth, is therefore little fitted to 40 enjoy retirement ? for riches do not bring con- tent. When he comes to retire, he is of all men the least satisfied ; for his easy circum- stances become the root of all his evils j and from having no longer any motive for action, he falls a certain prey to low spirits. These are the persons in this age, when riches are so generally diffused, that makeup the bulk of hypochondriacks in this country. So certain it is, that happiness in this state of being, ra- ther consists in the pursuit, than in the pos=* session of our object. All those employed in the public offices of government, and in the houses of trading companies and banks, come within this class : they are all distinguished by a sedentary me- thod of life within doors ; and when they pass the middle age, are often troubled with indi- gestion and low spirits. 3. The idle and dissipated.—This is also a numerous class in every great town. These persons are the subjects of diseases which ori- ginate chiefly from excess and debauch ; and not unfrequently spectacles of misery the most humiliating to human nature. Such dis- orders appear especially in the prime of life ; 41 often in early youth ; and if they are not fatal before forty, they introduce premature senili- ty, decrepitude and fatuity. A large city or town may be truly called a hot-bed for the passions ; all the vices that more particularly enervate the constitution and injure health, can be there practised long without suspicion or restraint, and indulged to the utmost: thus the young and inexperienced are quickly ini- tiated into every fashionable folly, and a vor- tex of dissipation. The sexual appetite is prematurely excited by the numerous hordes of unfortunate women that are permitted to range the streets.. The powers of procreation are thus weakened beyond recovery, before the body has acquired its. full stability and growth j. and the vigour of constitution as well as the faculties of mind are shook to the very centre. When such debilitated beings have progeny, the sins of the father are visited up- on the children, and they appear a race of in- valids from- their birth.. But as there is a disease the peculiar scourge of unlawful embraces, so its effects on health are equally disgusting and dangerous. The inconsiderate young man who contracts d2 42 this complaint, from delicacy often conceals his misfortune till it has gained a degree of virulence not to be described. This distress is frequently aggravated by mental sensibility } and families and connections are at once in- volved in general calamity. In the advanced stage, hideous ' rroity of body is often the consequence ; bv in all the gradations of this infection, a long and rigorous course of mer- cury is the only remedy to be depended on.— Mercury, rendered anti-venereal and poiso- nous by oxydation with the different acids, is considered a certain cure for syphilis ; but its exhibition is sometimes fatal to the consti- tution, and constantly leaves behind it a weakened frame of nerves, and a disposition of stomach and bowels liable to spasmodick affections. All full livers and drunkards come within this class. Frequent surfeits from high-sea- soned food ; and frequent intoxication from vinous or spiritous potations, commit dreadful ravages on the human body and mind. It is a misfortune in polished society, that many indulge in these excesses without thinking they are doing wrong; and often sink into the 43 grave by diseases of their own creating, with- out being warned of their misconduct. The disgusting propensity to luxurious eating for- tunately is seldom the case with the fair sex ; but where it happens, a train of nervous and bilious complaints are more certainly the con- sequence. To devour a large quantity of food is only a bad habit; most persons could be nourished with h\^'^hat they feed on ; so that not only temperance as to quality, but ab* stemiousness as to quantity, is one of the gol- den rules of health. 4. The artificer and manufacturer.—The numbers of this class are daily increasing j the natural effect of the vast commercial wealth of the united kingdoms. The artisan and manufacturer arc not confined to the town ; for almost every village throughout the country possesses some branch of manufac- ture. Here again all the effects of a sedentary life appear, the uneasy posture and unwhole- some air. But many species of manufacture are unhealthful from noxious metalick fumes to which the Workmen are exposed, such fc9 those of mercury, lead, copper, &c. The ex- hausting heats of furnaces, smelting houses) 44 laboratories, ovens, boilers, Sec. in different kinds of employments, have their diseases ; but the most noxious are those which fix on the nervous system. Those trades also where the articles wrought give out considerable quantities of unrespira'de gases, from the de- composition of animal and vegetable matter, are insalubrious ; the workmen commonly look pale, sallow, and dejected. Such persons as are exposed to the heat of large fires in their labour, and undergo sudden changes of temperature, cannot fail of being soon exhausted in constitution. As far as I have obtained information, it does not appear they live long. Their profuse perspirations, induced by hard work, as well as by great heats, give most of them a propensity to drink- ing. Were they always to quench their thirst by water only, the excessive labour might be borne for a length of time ; but the strongest malt liquors, often mixed with spirits, are the common drinks of men employed near fires.. I do not find that the pitmen in the coal mines of this district aie liable to any particu- lar diseases ; when temperate in drinking, they commonly live to a great age.. 43 5. Those employed in drudgery—This class is composed of both sexes ; they grow strong and broad shouldered from labour, provided it is chiefly out of doors. But in this class we often observe many addicted to drunkenness ; and I much doubt if their work is ever so severe as to injure health, when they are re* gular livers.- It may hov/ever be considered a9*a factr substantiated by the daily experience of phy- sicians, that all the diseases which are caused by hard labor, poverty, and want, are much easier of cure, than those which arise from in- dolence, luxury, and debauch. A constitu- tion that has been weakened by subtraction of nourishment, may soon have its energies re- stored by suitable regimen, diet, and medi- cine : but the frame that has been wasted of its vital powers by excessive stimuli and de- bilitating pleasures, has seldom or never been brought to its former strength. 6. Persons returned from the colonies.—-It is very common in the present times, for men brought up to business, to spend a number of years in the colonies, till they are able to re- turn with fortunes. They may therefore be 46 considered as a distinct class in this enquiry.. These persons bring with them indelible marks of the effect of the climates they have lived in : dyspeptick complaints, and all their nervous accompaniments, are the never-failing diseases of this enervated people. The tropi- cal heat, and luxurious modes of living, are chiefly to be blamed in the production of such bilious and nervous ailments ; and they have usually taken so deep a root in the constitu- tion, that they are rather aggravated than re- lieved by our variable atmosphere. The fog- gy weather, and fickle temperature of Britain, keep the feeble nerves of these relaxed frames in a state of constant irritation. The diseases of tropical climates, but par- ticularly the fevers of some countries, weaken the nervous system, produce great mobility, and a disposition to spasmodick complaints. Hence the chylopoeitick viscera become the r.eat of so many painful affections ; and'th'j word bilious has grown a theme of constant conversation in England, as well as in the co- lonies. 7. The female sex.—Nature has endued the female constitution with greater delicay 47 and sensibility than the male, as destined for a different occupation in life. But fashionable manners have shamefully mistaken the pur- poses of nature ; and the modern system of education, for the fair sex, has been to refine on this tenderness of frame, and to induce a debility of body, from the cradle upwards, so as to make feeble woman rather a subject for medical disquisition, than the healthful com- panion of our cares. The medical literature of the present day, affords abundant, but me- lancholy proofs of the justness of this remark. Their whole tenor of living, and domestic eco- nomy, are at variance with health. The fe- male infant before she can well crawl along the floor, is taught some employment that will -encourage her to sit, to stoop, or to walk two- fold. That it should be rude for an innocent young girl to run about with h:jr brother, to partake of his sports, and to exercise herself with equal freedom, is a maxim only worthy of some insipid gossip, who has the emolu- ment of the family physician and apothecary solely in view. A man of fortune and wealth, when he builds a stable or a dog-kennel for his horses or hounds, takes care that these compa- 48 titons of his field-sports shall He duly preser- ved sound in wind and limb, by frequent exer- cise out of doors, when he does not hunt.— But in no part of his premises do you see a gymnasium for his children. It the inge- nious arts are chiefly to be valued as they in* crease the sum of human happiness, we thus make it a misfortune by having a house over our heads, though it may shelter us from the frost, the tempest and the rain ; for it too ok ten becomes the means of depriving us of health, when it prevents exercise and excludes pure air. But we indulge our boys to yoke their go-cart9, and to ride on long rods, while little miss must have her more delicate limbs crampt by sitting the whole day dressing a doll. Ancient custom has been pleaded in fa- vour of these amusements for boys, as we read in Horace : Vut it is no where recorded, that the infancy of Portia, Arria, and Agrippina was spent in fitting clothes for a joint-baby. All female employments that are perform- ed in the sitting posture, injure health ; and are hurtful in proportion to the early age in which they are begun. Few of the sex are entirely free from this habit. 49 Women of very moderate fortune, and the •wives and daughters of all reputable trades- men, in this country, maybe said to indulge in most of the follies of their superiors. They can have their hot close rooms, drink strong hyson, and keep late hours, as well as a dutch- ess. The female constitution, therefore, fur- nished by nature with peculiar delicacy and feeling, soft in its muscular fibre, and easily acted upon by stimuli, has all its native ten- derness increased by artificial refinements. Hence the diseases of which we now treat, are in a manner the inheritance of the fair sex ; when to these we superadd all the preposte- rous customs of fashionable life, need we won- der at the numerous instances of bad health and feeble existence so often to be met with among them ? One of the curses which was pronounced against some of the Jewish mothers, is unfor- tunately realized among many of our fair coun- try women.—u The tender and delicate wo- " man among you, which would not venture " to set the sole of her foot upon the ground, " for delicateness and tenderness, her eye " shall be evil towards the husband of her E 50 chain of feeling with one another, of a more exquisite kind than is to be found in any other part of the system, or from any other disease. The degree of the effect on these parts, will be in proportion to the sensibility of the temperament; and in many subjects we find hysterick fits, epilepsy, and other convul-' sions, tetanus, menorrhagia, amenorrhea, &c. take place in an instant, from mental sympa-- thy. One of the most common causes of nervous, bilious, and stomach complaints, is excessive or long protracted grief. Mothers who have lost children, particularly suffer un- der these painful affections. I believe the at- tachment of a mother to the infant, is by far €3 the strongest of all human passions. Medical attendants are in the daily practice of seeing these parental feelings, exemplified. We read in Tacitus of a Roman mother dying by the rack, rather than discover the place where her son was concealed, during the contest be- tween Otho and Vitellius. In some instances of maternal affliction, we have observed the faculties so powerfully oppressed by sorrow.; so absorbed in the contemplation of one ob- ject, that the mind appeared almost or wholly .unconscious of its own existance, and scarcely attended to a single external impression. In such cases the intervals of reason, or con- sciousness, were only to be marked by sighs, groans, and tears, as the expressions of grief. Shakespeare has beautifully painted this pas- sion, in the lamentation of Constance for her son, in King John : ■Grief fills the room up of my absent child, Lies in his bed, walks up and down with me, J'uts on his pretty looks, repeats his words, Remembers me of all his gracious parts,. Stuffs out his vacant garments with his form ; Then have I reason to be fond of grief ? O Lord I my boy, my Arthur, my fair son ! My life, my joy, my food, my all the world. 84 Some such expressions as these might have been uttered by the mother of Sisera, when she heard of his death, if it did not at once deprive her of life. The sacred histo- rian describes in such glowing language her expectation of his return, that he probably withheld the rest of the narrative, from find- ing terms unequal to express the struggle of maternal feelings, in the transition from hope to despair,* When David received the ac- count of Absalom's death, he appears to have been so overwhelmed by it, as to be insensible tp a victory that secured both his life and his crown. Was ever grief depicted in more plaintive measure than in his exclamation on *The mother of Sisera looked out at a window, and cried through the lattice, why is his chariot so long in coming ? Why tarry the wheels of his chariots ? Her wise ladies answered her ; yea, she returned answer to herself, Have they not sped ? * Have they not divided the prey, to every man a damsel or two ? To Sisera a prey of divers colours, a prey of divers colours of nee- dle-work, of divers colours of needle-work on both sides, meet tor the necks of them that take the spoils ? Judges, v. ^B-~S0. 85 this occasion ? 0 my son Absalom, my son, my son Absalom : would to God I had died for thee, 0 Absalom, my son, my son .'* We cannot contemplate such violent in- stances of natural affection without suspicion of health being injured thereby ; and though not immediately apparent, the effect will strike a quick observer in the event of disease. Next to these heart-rending emotions of parental sorrow, may be reckoned the effects of disappointed love, on the sensible female frame. In the male sex, the active pursuits of business or pleasure, more quckly supplant tender impressions : and men much sooner regain that mental tranquility which fits them for the busy scenes of life. This is not the case with the fair sex ; for the influence on both body and mind, seems to be in propor- tion to the concealed struggle of attachment. The heart obtains relief in pouring forth its complaint, and acquires resolution when this. is done : but the hidden passion burns the fiercer by being suppressed.'!; The separation * 2 Samuel, viii, 33. j--------She never told her love ; But let concealment, like a worm in the bud, H - ft 66 rof the parties, and long engagements that pro- crastinate marriage, are often fatal to health. The condition of mind, alternately, passed be- tween hopes and fears, is worse than certain disappointment; hence the state of suspence, to persons of nice sensibility, is always deem- ed the most tormenting. It is this conflict between attachment and -secrecy, that has often given birth to the em- phatick expression, " dying of a broken heart" But such afflictions of mind commonly, sooner or later, produce some disease of the nervous system, which quickly draws into consent the digestive organs, and others of equally acute sensibility. Hence a certain hue of the coun- tenance is said to mark a melancholy and des- pair, which is brought on by vitiated digestion and imperfect assimilation of the food. As the manners of the age must always .materially influence diseases of the nervous class, so among their moral causes ought to Prey on her damask cheek: She pined in thoughjt, And, with a green and yellow melancholy, She sat, like patience on a monument, Smiling at grief. Shades?. 87 be reckoned religious melancholy, and enthu- siasm ; jealousy, avarice, insatiable revenge, boundless ambition, envy, misfortunes in bu- siness, and some species of pride. All these, in their various operations on the human mind, excite extravagant hope, or abject depressions of spirit ; in the issue, harrass the nervous system; produce watchfulness, or unrefresh- ing sleep, engender tumultuous passions, im- pair the appetite, and disturb chylification. To these succeed spasmodick, bilious, and hypochondriacal complaints; all of which center in the organs that prepare and assimi- late the nourishment of the body. Some of the severest instances of these diseases, which have come under my care, were in officers ; men endued with acute sen- sibility of mind, of fine parts, and with high notions of honour. They had been long tan-< talized by promises of promotion, and lived to see unworthy favorites put over their heads. Similar cases are too often met with among other conditions of life; where worth, virtue, • and talents, must give place to wealth, servi- lity, and intrigue. The passion of novel reading is entitled to 8B- a place here. In the present age it is one of the great causes of nervous disorders. The mind that can amuse itself with the love-sick trash of most modern compositions of this kind, seeks enjoyment beneath the level of a rational being. It creates for itself an ideal world, on the loose descriptions of romantick love, that leave passion without any moral guide in the real occurrences of life. To the female mind, in particular, as being endued with finer feeling, this species of literary poi- son has been often fatal ; and some of the .most unfortunate of the sex have imputed their ruin chiefly to reading novels. How cautious then ought parents to be in gaurding against the introduction of these romances among their children ; so calculated to induce that morbid sensibility which is to be the bane of future happiness ; which to prevent is the task of a correct education ; which first engen- ders ardent passions, and then leaves the mind without power to resist or subdue them. It is lamentable that three-fourths of these pro- ductions come from the pens of women ; some of whom are known to have drank deep of the fountains of pleasure and adversity. 8S The drama is another hot-bed of thi3 dis- eased sensibility. It has been long ago re- marked, that few English comedies were suffi- ciently pure for the ear and eye of a chaste and virtuous woman. But if such scenes are to be found among them, the sentiments they ex- press cannot be much improved from the mouths of some first-rate actresses, who live openly as kept mistresses. We are very little obliged by the late importation of a few loose German plays on the English stage. They are the offspring of a new school, and commu- nicate poison in a new way ; such poison as has no antidote on the shelves of the apothe- cary.- 6. Intense study.—Severe mental applica- tion depresses the nervous power ; and whe- ther this arises from business or pleasure, the ultimate effect seems much the same. Intense thought appears to subtract a great share of excitement from many corporeal organs : when long continued, or often indulged, it leaves them in a state of direct debility. Ma- thematical studies are said to have this effect more than others ; and among some intimate friends I have known these effects. But it b H2 90 to be observed, that persons attached to the mathematical sciences, are commonly men of cool judgment, of deliberate modes of think- ing, not easily diverted from their pursuits, and rather of a torpid nervous system. Their complaints therefore assume much of a hypo- chondriacal cast. Among people of a more mobile habit, severe study excites in the first passages, a disposition to spasm and convul- sive motions, amounting frequently to what is called the hysterick affection, or globus hyste- ricus. The abdominal viscera particularly feel on these occasions : the strong exertions of the animal functions abstract or expend much of that energy or sensorial power, which ought to be alike diffused over the natural and vital actions. The appetite flags ; the bowels become slow ; flatulence and acidity super- vene from imperfect digestion ; the bile is se- creted in small quantity, and its flow into the duodenum often obstructed ; dyspnoea is a common attendant; syncope not unfrequently happens, and degection of spirits to such a de- gree, as to reduce the philosopher to an idiot. .Emaciation of body quickly follows this course of life j par.tly owing to vitiated sanguification, 91 but perhaps also from obstructions in the lacte- als and mesenterick glands. The pallid colour of a hard thinker, or severe student, may therefore be imputed to dyspepsia, or to de- oxygenized blood, from confinement within doors. Young men who are ardent in pursuit of knowledge, and greedy of literary fame, often lay the foundation for stomach com- plaints at the university, that are never after* wards to be overcome. Persons much attached to musick, as being furnished with acute nerves, and nice sensibi- lity, and of a sedentary turn, are often harras- sed by these diseases. This remark, indeed, applies to all who may be considered as vota- ries of the fine arts. Such people, whether male or female, have commonly a predisposi- tion to nervous disorders. I have met with many obstinate cases among schoolmasters ; in part to be attributed to confinement within doors, but chiefly to stu- dious habits. But what is still more strange, I have even known them among shepherds, a class of men enjoying the purest air, but be- coming nervous and hypochondriacal from an inactive solitary life, and a thoughtful mode of 92 3pending time, and reading abstruce subjects.- 7. Lactation or nursing. —»T'his office of the mother to the child, if the dictates of nature deserve attention, ought to be considered as a very salutary duty ; for if we look to the na- tural state of mankind, we find every mother able to perform it. The child-bearing part of life is usually healthy;.and weakly females have their health improved by becoming mo- thers. It must, therefore, be owing to some deviation from the established rules of the animal economy, that so many women are to' be found unequal to this task. It is the duty of the husband to encourage the wife in the exercise of this amiable attention to the infant; and if he prevents it, he rends asunder one of the strongest ties of human affection. Yet we often see mothers-so attached to the office of nurse, as to view the weaning of their child with horrour: such feelings dignify human nature ; what a pity there should be found ex- ceptions to their being general. It would appear to be the indication of na- ture, to suckle the infant till it is nine months eld, as corresponding with the time of gesta lion, At this age the child is capable of takinj °1 other nourishment for its support. But when the mother grows too delicate and weak for the office, it must be weaned sooner. The complaints which are brought on by long suck- ling, are much the same with those that follow frequent abortions, and immoderate or irregu- lar menstruation. They are all of the nervous class. As the regular peculiarity of the sex, is the best test of female health, so the vica- rious lactation may be considered as a relief to the other organs, and thus beneficial. But when continued too long, the general frame is debilitated, and particularly the uterine sys- tem. The strength of the woman is not re- duced by affording nourishment to the infant merely ; it is the sympathy which subsists be- tween the different organs that give birth to morbid feelings, and the stomach and intes- tinal canal v/ith many others are quickly drawn into consent. Mothers who trust their children to hired wet nurses, would do well to inform them- selves how far these women have weaned their own children with satisfaction. Few mothers, among the decent orders of women, can be supposed to leave their offspring without 94 regret; and it may happen that the health of the other infant is liable to suffer in the con- flict. Much pretended refinement often takes place about selecting a nurse free of disease : but what scrutiny can secure the suckling against the bad effects of her passions; these must frequently sow the seeds of future indis- position, that may not be discovered till too late. A mild and serene condition of mind must be a valuable ingredient in the character' of a nurse ; for which reason the nervous con-' stitution should be avoided. On the whole, a; hired nurse is only a lesser evil, that can by no means repay the offspring for the want o£ the mother's breast. But nursing mothers among the lower orders of women, if they remain with their families, are often badly nourished : and if they feed much on tea, are subject to that species of consumption that is denominated nervous. This is, in fact, a high degree of nervous exhaustion and debility, attendedswith many of the most painful symptoms.* To keep the * All wet nurses ought to abstain from tea. Next to' spirits and malt liquors, it is most hurtful to the suck- ting.. Q5 child at the breast for 18 months or two years, cannot be done without injury to the mother's health. Yet this practice is frequent, and must be considered as a sad alternative to pre- vent the quick increase of a family. 8. Miscarriages andpremature labours, &?c. Few mothers who have suffered mishaps dur- ing pregnancy, escape with impunity. All miscarriages are attended with some degree of danger, and much bad health is with justice imputed to them. The wife who has prospects of being a mother, must undergo much men- tal distress at being disappointed, independent of all personal hazard. This species of anxiety is one great cause of one.miscarriage being so apt to succeed another, as the mind is trem- blingly alive to every symptom that resembles :the former. This state naturally begets a nervous sensibility, which too often creates ^imaginary fears when there are none real. Long and severe labours, to which may be added some of the diseases of the puerperal season, are also to be considered as a frequent -source of nervous disorders. Large evacua- tions of blood at that period are known to in- duce the most violent hysterick paroxysms and 96 other convulsions ; hence these affections so commonly follow floodings during labour and after it. The changes which take place in the breast and womb after the birth, very materially affect the general system of nerves. These evolu- tions are marked by increased irritability, and fevers of the most acute kind are liable to supervene ; and point out the necessity of a soothing regimen, tranquility of mind, pure air, mild diet, open bowels, &c. If there is a hereditary predisposition, nervous ailments will, of course, more readily appear, and be aggravated by all improper treatment. 9. Climate.—In the description of the in- habitants of a large town, I have mentioned persons returned from the East and West In- dies. Such persons are remarkably subject to the diseases of which we now treat. The acute fevers of tropical-climates in a particular manner affect the stomach, bowels, and biliary secretion. The yellow fever of the West In- dies derives its name, and part of its charac- ter, from the excessive flow of bile ; which not only tinges the serum of the blood, the urine, and skin, but in a manner inundates 97 the intestines. No pain or tention in the region of the liver, accompanies this unusual secretion ; and the bile is taken up by the ab- sorbents, enters the circulation, and produces yellowness of the surface, without any obstruc- tion of the ducts as in jaundice, for the faeces are highly bilious. There seems to be little resemblance between this endemick of the West, and the hepatitis of the East Indies. I would therefore call it, as has been done by one of the best writers on the subject, Can- sos.* In the hepatitis, an excessive biliary secretion is not mentioned. The West India fever is always rapid in its progress ; but the liver disease of the East is often so chronick in its form, as to steal on imperceptibly for months, without pain sufficient to create unea- siness or alarm, though it may at last arrive at suppuration. They both affect chiefly young robust Europeans, new-comers, who live full, and drink freely of vinous liquors. The same modes of living, we know, create hepatick diseases in England ; and the analogy extends to other pampered animals, as the domestick, 1 Dr. Moseley en Diseases of the West Indies. i 98 fowl, turkey, and pig. Both diseases leave the digestive powers in a weakened condition; and there are few who do not complain of a degree of dyspepsia after these attacks. But in a multitude of cases where I have been con- sulted, by persons returned from India, it was doubtful to me, whether mercury exhibited aa a remedy, or the disease itself, were to be most blamed for the production of dyspeptick affection. As far as I have been able to learn, from both written or verbal accounts, this complaint, so frequent on the Coromandel coast, ought to be treated with large bleedings, and copious active purgatives, in the very first attack. The quantity of blood to be taken, I think, ought not to be regulated by rules laid down by systematick writers for the inflamma- tory fevers of this country ; if it is done at the proper period, it ought to be infinitely larger. If these evacuations have been neg- lected, or sparingly employed, suppuration, torpor, or infraction of the liver, to a certainty succeed, which render the use of mercury in- dispensible. Where the disease assumes at first the chronick form, mercury is considered the only remedy. The phrase, " chronick in- 99 flammation" is a new term in medicine, and I think an improper one here. The less active hepatitis is still a febrile disease, only less mark- ed ; for how can we suppose purulent matter to be generated without those distinguishing phe- nomena that are characteristick of it. The mer- cury in this case, I should suppose to act partly on the biliary pores and ducts, partly on the circulation of the liver, but chiefly on the ab- sorbents of that viscus. These effects from mercury being so well known, why contend for it as a specifck, in this oriental disease? It would therefore appear, that there is a peri- od in hepatitis, when it is indicated and safe ; and as its stimulant powers are so evident, that must be, when the symptoms of active inflam- mation have subsided. We thus see how fric- tions in some nervous constitutions, must be the most eligible way to direct this medicine, as some authors contend. Yet mercury, nev- ertheless, at all times has a manifest action immediately on the nervous system ; and if limits can be drawn to its exhibition in the different stages of hepatitis, care should be taken that the habit is not destroyed by it, and diseases worse than the original pne produced. 100 But if this treatment deserve all the encomi- ums which has been given it, how comes it that so many return to this country labouring under the liver complaint, as they call it, after having repeatedly undergone the mercurial course. The consequences of tropical fevers will, however, be in a great measure prevented as the effusion of cold water gets into universal practice ; and employed with the precaution? directed by two great physicians of the present day, my late lamented friend Dr. Currie, and my learned friend and neighbour Dr. Jackson of the army. In the acute hepatitis it promi- ses to be an effectual remedy. Much reason- ing has been employed on the cause and treat- ment of fever ; but no certain method of cure was ever given to mankind before the cold ef- fusion. We can now readily admit, that the sudden abstraction of a great quantity of heat, by the shock, as it is called, dissevers in an instant those associated actions which consti- tute the febrile phenomena ; or what is em- phatically said, to cut the fever off at once. The hepatitis of the East Indies, as affec- ting an organ so necessary to the cnimal eco- 101 nomy, may have thus a large share in tne duction of dyspeptick complaints. The effects of a warm climate on,the he- patkk system, and producing a redundancy of bile, admit of much speculation. A warm summer in this country has a similar effect ; in such a season, cholera and dysentery are common. Excessive heat may be regarded as it acts on the nervous and sanguiferous systems. It powerfully increases the sensibi- lity of every part; and renders the mind more susceptible of pleasurable sensations. The muscular fibre becomes more irritable ; and what are called spasmodick complaints, are more common in warm than in cold regions. Fevers also are more frequent than in Europe, in which the stomach is much diseased, and bilious vomiting, with a yellow tinge of the tunica adnata, are attendant symptoms. Inso- lation is the effect of the rays of the sun in a perpendicular direction, acting on the sensori~ urn commune. The last degree of debility, with bilious vomiting, indicates this affection ; just as we observe severe hurts or wounds of the head induce the same symptoms. Now we explain these symptoms from the nice con* i 2 102 sent of parts ; they prove the strong sympathy with which the chylopoeitick organs, by their office are linked with the functions of the brain. The excessive heat is an exhausting power, directly acting on the sensorium com- mune ; for compression of the brain, from blood or other causes, does not excite the same train of symptoms. We therefore draw the conclusion, that warm climates induce hepa- tic and stomach diseases, by primarily affecting the nervous system. As far as heat affects the circulation of the blood, it seems to have little effect in bringing on nervous irritability, and is of inferiour consideration in this inquiry. But while we blame the'heat of the climate for the production of nervous and bilious dis- eases among Europeans, we must also take into account their modes of living, so injurious to health. The most debilitating of all plea- sures, is by them indulged to excess ; and the passion seems to grow from what it feeds on. Highly seasoned food, the large use of vinous liquors, and licentious manners, carry luxury to its utmost pitch. The warmth of the cli- mate is, therefore, not to be singly blamed in engendering bilious aud dyspeptick com- plaints. 1.03 If persons who live in this way, remain in a tropical country till they pass the meridian of life, and then return to Britain, they seldom enjoy good health. The cause of this is ob- vious. They ought therefore, if convenient, to pass their first winters in some of the sou- thern provinces of France, or in Spain, or Portugal; and thus accommodate the consti- tution gradually to the great change of tempe- rature. i Some districts of country that are low, swampy, and subject to fogs, commonly disa- gree with nervous and bilious people. And those seasons, when the weather is variable, and liable to sudden transitions, are also hurt- ful. Many of their symptoms, particularly depression of spirits, increase under a cloudy atmosphere ; hence the glooms of November are proverbial for having this effect. 10. Medicines.—All nervous persons are uncommonly fond of drugs ; and they are the chief consumers of advertised remedies, which they conceal from their medical friends. Among some well-meaning people, this inor- dinate desire for medicine has frequently be- come of itself a disease. With many of them 104 physick, to be useful, must be clothed in mys- tery ; and the moment a discovery is made of the composition, the confidence is lost. Me- dical attendants have too often brought this punishment on themselves. Were they unani- mous in combatting the prejudices of mankind, by candour and openness of conduct, by a fair avowal of the imperfections of their art, and the honest confession that articles of Materia Medica, form but a small portion of its re- sources, they would not so frequently see their commands disregarded, or learn that their compounds have been thrown Out of a window. This is the only way in which I can account for so many persons of good sense and discernment, consigning themselves and fami- lies into the hands of impudent and illiterate quacks. It was the saying of a very sagacious pro- fessor of medicine to his pupils, " young gen- tlemen, if your medicines should do no good, take care that they do no harm."* When ac- tive medicines are long continued, and do not • The first Dr. Rutherford, professor of medicine in the University of Edinburgh. 10J cure, it is very likely they may do mischief. But the remedy that cures one disease, if inju- diciously administered, not unfrequently pre- disposes the body, and paves the way to ano- ther malady. I shall begin with Emeticks.—The exhibition of emeticks is often taken out of the hands of the medical profession ; and every good woman thinks herself competent to direct a vomit. Some people with delicate stomachs are in the habit of taking these articles, for every uneasy state of that organ, which is construed into.a foul stomach. But nothing can more certainly tend to weaken, nay paralyze that viscus. The operation itself is painful and unnatural ; for the act of vomiting, is to invert and evacu- ate the contents of the stomach the wrong way. This cannot be done without medicines that are first highly stimulating : they pass through the stimulant stage of the process first; and when that is over, the fibres of the stomach being exhausted for a time, sickness is the consequence and vomiting succeeds it. This nausea is sometimes so severe as to oc- casion fainting, and even convulsions ; and the frequency of the pulse during the opera- 106 tion is often so reduced as to give serioue cause of alarm ; and is at all times slower till the sickness is overcome. Such are the symp- toms to be marked during the emetick effects of tartarized antimony, vitriolated zinck, vitri- olated mercury, ipecacuanha, squill, &c. If therefore, this operation is too frequently re- sorted to, what is to be expected but a weak- ened, mobile or torpid condition of the sto- mach, and every organ that fills a link in the great chain of sympathy with it ? The hurtful effect is also much increased by the copious draughts of warm water, taken to encourage the vomiting. At the time that James's Powders were in general use, and when families were in the practice of taking that medicine as a preven- tive of fever, at stated periods, weakness of stomach and indigestion were often traced to this cause. Ignorant people are apt to consi- der many complaints where the pulse is quick, as fevers, and fly to improper remedies. But antimonial emeticks require the ut- most caution in the exhibition to nervous people, and all who possess irritable bowels ; •uch as dyspeptick and gouty ; severe cramps, 107 hystericks and diarrhsea, too commonly fol- low. They likewise encourage eructation, and by inverting the gullets of some people, a kind of ruminating of the food takes place, a habit very disagreeable and disgusting.— When we reflect what a small portion of anti- monial preparation is required to excite vomi- ting, we must be convinced of its uncommon activity, and that it acts immediately on the nerves of the stomach. The same guarded practice applies to all the metalick oxides, when used as emeticks. What may at season- able times be a valuable remedy, may thus, by being improperly directed, have the most baneful effects. Nervous patients are parti- cularly subject to a kind of rising in the car- dia, or upper orifice, a sort of inverted motion in some of the muscular fibres, with disten- tion, flatulence, and acidity, that create vast sickness. But to have recourse to vomits for relief, would only aggravate the complaint. These persons are also more easily affected by disagreeable objects, and bad smells, than. others, which harrass them not a little. As they grow acquainted with this frailty of their stomachs, they will rather study to avoid the 108 causes, than trust to any article of medicine for relief. When constant vomiting has been brought on, in nervous stomachs, by whatever means, no complaint is more difficult to be re- strained : some afflicting cases of this kind have come within my knowledge, in young persons, part of which terminated fatally. Purgatives.—This class of medicines, like the preceding, are too often directed by improper judges of their fitness. But the greatest harm is done in infancy and child- hood, when parents run to the aid of physick for every trifling complaint, but chiefly for cutaneous affections. It is immediately deci- ded that these spots are owing to bad humours and foulness of the blood, and must be carried off by a purge. Such reasoning as this for- merly prevailed among medical people ; we cannot therefore be surprised that persons not in the profession Should still retain a little of the old leaven. Purgative medicines differ extremely from one another; and if it is a nice point in medical practice to suit the purge to the nature of the complaint and pe- culiarity of constitution, it must be oftea dangerous to trust them in common hands. I 109 was once called to visit a farmer who had ta- ken two ounces of saltpetre, instead of Glau- ber's salt. I found him in extreme pain about the stomach, with ghastly looks, an intermit- ting pulse, and cold sweats. A few minutes longer would have been too late to save him : by drinking plentifully of warm milk and wa- ter, and a brisk emetick, he was recovered. But I have known similar cases prove fatal. Confinement within doors, a uniform mode of living, and sedentary habits, are so com- monly met with among persons of the nervous temperament, that a constipated state of body is a general condition of their disease. Hence the frequent recourse to medicine for opening the bowels. Some of the most drastick pur- gatives, such as aloes and scammony, come at last to be in common use with them. This custom soon begets a habit; when the bowels are brought to that torpour and inactivity as never to be moved without the aid of a drug. The sensibility of the intestines is thus, by de- grees worn out; the lacteals which take up the food, the mucous glands and exhalants that pour forth fluids, as well as the nerves and nvisouhr fibres, grow torpid : the consequence K. 116 is the loss of the peristaltick power, and the bowels are apt to run into inverted motion, and spasmodick constriction,till a fatal cholick, an intusception, iliack passion, or cramp, close the scene. Painful diseases of the rectum, schirrus, hemorrhoidal tumours, and .fistula, too often render life miserable, from this ill- conducted practice. * But if mercury, in the form of calomel, or any other preparation of that metal, makes part of these habitual purges, the consequences are always to be dreaded. Calomel is a favo- rite article with some physicians, as a purga- tive and from the minuteness of its dose, very desirable to the patient. It also operates quickly and briskly ; which with nervous and dyspeptick subjects, is matter of great satis- faction ; for their odd ■feelings and singular sensations within, give the suspicion that they are full of obstructions and cannot he suffi- ciently evacuated. Yet such instances of slow bowels are not to be considered as depending altogether on a local affection. They are join- ed with a general state of the body, and only to be radically cured by correcting the original evil. Thus a long walk out of doors, and a lit fittle active exercise and recreation ; will effect sometimes what large doses of medicine are unable to perform. But mercury is the most dangerous of all frequent purges ; it sooner exhausts the irri- tability and vital power of the intestines, thaa any other metalick oxide, except arsenick. It never fails in the end to add to the disease : it is peculiarly contra-indicated in the nervous temperament, fronv the mobile disposition of nerve ; and its action on the bowels, very much resembles a state of dysentery, by pro- ducing the most violent gripes and tenesmus. It thus frequently brings on prolapsus ani, a complaint to which weak bowels are liable, and especially women, who have experienced hard labours, and borne a number of children. Many volumes have been written on disea- ses, supposed to have originated from the use of mercury, when given for the cure of lues venerea : yet, strange to relate, its most com- mon consequences, dyspeptick and nervous affections are scarcely mentioned.* I firmly * A little tract, " On the Use and Abuse of Mer- cury," has just been published by Dr. Wilson; in 112 believe all the derangements which it occa- sions in the body, are small when compared with the injury to the nervous system and di- gestive powers. Some physicians and sur- geons even fly, in common cases, to one of its most dangerous preparations, hydrar. mur, and seem to overlook it3 ultimate effects on the constitution. It has often been my lot to witness these effects in the practice of others : for of ffty thousand cases of the venereal dis- ease, which I have attended, I am convinced that not one of the number ever required this acrid mercurial. Haemoptysis, ending in phthisis, was a frequent sequel to-this treat- ment. It is well known that miners and worker* of this metal in the various arts, are, after a certain time subject to the most violent ner- vous afflictions, such as cholicks, epilepsies, which he particularly notices its hurtful effects on the stomach and intestines. I am glad to observe, that his remarks are very much like my own. This essay ap- pears to be only a prelude to more extensive disquisii tions on the subject.; which I hope the learned author vill follow up with his accustomed ability. * 113 cramps, tremours, &c. and the last stage of these is palsy, in its most hideous form. In the silver mines of Spain, in South America, where mercury is employed to separate the gold, the poor slaves seldom live three years, from being exposed so much to its fumes. Hence to be sent to the mines, implies the last degree of human punishment. As the lues venerea extends in society, and the exhibition of mercury for its cure becomes every day more familiar with medical people, there is danger they forget they have in their hands one of the most active mineral poisons, and extend its use to all those diseases that resist other remedies. In the hands of the ignorant and indolent of the profession, it has done in- calculable mischief. The ignorant man is neither capable of selecting its proper prepa- rations for particular conditions of body, nor of knowing when it is forbid ; and he is una- able to discern when it has done harm. The indolent among us, who give themselves no care about the investigation of a distemper, cannot be fit persons to prescribe an article that, injudiciously given, may destroy life. This remark does not merely apply to the k 2 114 vender of advertised remedies ; it compre- hends many in private life, who, from defi- cient education, are not entitled to more confi- dence than the itinerant tribe. But there is a form of the diseases of which we now treat, in which mercury is said to act with undeniable efficacy ; namely, in what are called bilious complaints. The term belongs to common language j as such, I have adopted it in my title ; but it is not correct in a medical nomenclature. Some members of the profession, to improve our vernacular idiom, have thought proper to give these ailments the name of liver complaints, as that organ is said to be their seat; but equally undefined in a scientifick view as stomach com- plaints, so long applied to diseases of the di- gestive powers. The phrase bilious derives its origin from that tinge of the skin so often observed in dyspeptick persons, who also oc- casionally pass bile both upwards and down- wards. Now bile, appearing in these forms, being a natural secretion made by the liver, is to be considered as the effect, rather than the direct cause of indisposition. In the present day, a dyspeptick person no sooner complain* 115 of pain in the right hypchondrium, than the liver is said to be diseased ; and a bilious suf- fusion of the surface* is considered an infalli- ble symptom of the same viscus being affec- ted ; and the mercurial process is immediately commenced. It is disgusting to hear this phraseology so common in the mouths of me-. dical people. It is well known that jaundice itself is even common enough during the mercurial treatment of lues venerea. We shall learn from a description of the nervous temperament, that persons subject to indigestion, to frequent discharges of bile, and spasmodick affections of the chylopoeitick or- gans, are endued with uncommon delicacy and irritability of the first passages ; and that this state is generally attended with great debility. Such a condition of the muscular fibres, in the osophagus, stomach and bowels, with all the canals which pour fluids into them, naturally makes the whole subject to reversed motions, irregular contractions, increased sensibility in one part, and deficient power, or torpour in another. The state of the liver itself will partake of all these irregularities. Its secre- tion will sometimes be suspended, sometimes 116 deficient. It will suffer stagnation in the bili- ary pores, and in all its ducts. Even when it flows freely into the duodenum, it will at one place be collected in greater quantity than at another; sometimes retained, and at others flowing profusely ; and the slow or quicker -motion of the bowels, will exhibit a proof of mis inconstant passage of the bile in the alvine discharge ; in its colour, its consistence, and fcetor ; while transient jaundice will also ap- pear. The ducts may also be obstructed by bilia- ry calculi, over which mercury has no power. Indeed dyspeptick persons are very subject to these concretions, which are probably owing to some disposition in the bile itself. These commotions will frequently bring on epileptick and hysterick convulsions, violent cramps, and death. The mind strongly sym- pathises ; it is irritable, irresolute, timid, des- ponding, and suffers *more or less such de- rangement in its relation of things, and in its perceptions, as amounts to a degree of deli- rium. This constitutes what, in common language, some persons call a bilious or ner- vous attack* 117 Thi3 being our explanation of the biliary affection of the nervous temperament, it must be straining facts to the utmost, to find any analogy between it and the hepatitis of the eastern hemisphere. How indeed can any qualified observer of the phenomena of dis- ease, compare the full robust habit of a young European, on the coast of Coromandel, with the weakly and delicate nervous lady of out climate ? Yet the analogy, monstrous as it is, in the practice of some physicians, has been said to be correct ; and dyspeptick and hys- terical females, have on the faith of this doc- trine, been tortured with mercurial courses, till their very teeth have been in hazard of dropping from their sockets ; and this plan of treatment sometimes repeated, as the symp- toms were found to recur. I hold it as an unquestionable fact, that a peculiar predisposition attends both diseases j and that local causes excite both. It appears from many particular symptoms, that a direct- ly opposite state of the body prevails in the two complaints. How then can the same me- dicine be indicated in both ? The icterus is not characteristick of hepatitis; nor is the ca- 118 pricious disposition of the bowels, and the mental disquietudes of nervous affection, ever included in the account of its symptoms.-— The analogy therefore between the hepatitis and the dyspepsia of the nervous tempera- ment, has no foundation in pathology, and leads to no rational method of cure. That the liver may be enlarged in these diseases, as well as from hepatitis, I readily admit: but such enlargement must be brought on in a ve- ry different manner. It must be chiefly ow- ing to the debility of the hepatick nerves ; by which means a torpor or kind of paralysis takes place ; effusion of some kind may then happen in the parenchyma of the river, which the lymphaticks are not able to carry off.— What are called tubercles of the liver, are most likely enlarged lymphatick glands and vessels ; this may be another cause of increa- sed size. But it is probable also, that the se- creted bile itself is frequently the cause of the great bulk, from torpor of the pari biliari and ducts. I believe however in dyspeptick ha- bits, that such increased size of the liver is a rare disease ; and when it does happen, it ought to be considered a3 an effect, not a pri-- 1.19 mery cause of indisposition. If therefore,,. there is much nervous predisposition, mercu- ry must do a great deal of harm, and add to the mischief. Some persons have an opinion, that mer- cury acts immediately on bilious affection, in- dependent of evacuation ; but this is fanciful. A purge, in which calomel is combined with a cathartick, as it excites the duodenum in its passage, it also urges into action the different ducts which open into it; and the last evacua-^ tions of a mercurial purge, are commonly bi- lious. This increased action may, by sympa- thy go farther ; the pori biliari may feel it, and perhaps the whole viscus* Thus the li- ver maybe purged, and excited to healthful action. But what one dose or two may effect, a third and fourth may destroy ; and by know- ing the constitution of the patient, we shall know when to stop. And as cramps and spasms, of the most painful kind, are part of these diseases, so mercurial purges, as I have often seen, run great hazard of bringing them on. But there are many purgative articles, that in these cases, have all the good effects of mercury, without the deleterious ones ; and 120 they ought to be preferred. Very active ex- ercise will also, in many instances supersede the use of medicine ; so great is the power of agitating the abdominal viscera, in promot- ing the due flow of bile. The hepatitis of the East Indies has been long considered a serious disease, and often fatal ; and as it has seldom yielded to a mild treatment, the exhibition of mercury is justi- . fied. But it cannot be denied, although this ts.t -^medicine is chiefly to be depended on, that e- ven in India it has done infinite harm to the constitution. I therefore embrace the oppor- tunity of quoting the following passage from the Edinburgh JN^edical and Surgical Journal, No. viii. p. 503. It is given without the wri-^ ter's name, but the cautions which it inculcates are of such great value in practice, that even anonymous authority renders it respectable. Extract of a letter from a surgeon on the Madras establishment, dated the 22d Octo- ber, 1805.—" My last letter from —gave " me sad accounts of his health. He is suf- " fering much from excessive use of mercu- " ry ; and has had, he says, spasms of the dia- " phragm, and excruciating pains in his skin, ' 121 « Jen?*, W head. It may be news to you, " that mercury in this country, when given in " too large quantity, causes sufferings more " dreadful than the disease for which it is a " specific, and experienced surgeons are cau- 44 tious never to exceed in its employment. " You ask me if the erythema mercuriale is " frequent with us ? Very lately a brother sur- " geon here had a case of it in his hospital " which terminated fatally ; and with the na- " tives who never can be made to clothe " themselves sufficiently, or almost at all, " when under the use and influence of mercu- " ry, this disease occurs frequently, and often " proves destructive." If such are the effects of mercury in robust constitutions, and in a climate peculiarly fa- vourable to its administration, what severities are we not to expect in weak nervous bowels, and in a condition of atmosphere, that in de- spite of every precaution, so often throws its activity on the.first passages ? It is to be hop- ed the advice given in this extract will not be lost on physicians and surgeons, in England, who are so apt to resolve every pathological L 122 difficulty, into a liver complaint; and pour in mercury ad infinitum. Mercury as a cathartick acts best in con- junction with jalap : a pill containing three grains of the latter to one sixth of a grain of the former, purges moderately in a hale state of body. I maybe told in contradiction to this, that a dram of calomel has been given to a child ; and half an ounce to an adult, in a few days, without any bad effect. But, be- cause these patients were not destroyed, is the heedless administration of so active a me- dicine to be justified by such proofs ? I havfe seen persons survive large doses of corrosive sublimate mercury and arsenick ; yet no judi- cious physician will compare these recoveries with the limited doses of either article, adapt- ed to the nature of temperament, and diseased 'state of his patient. Mercury being a medicine given in ajgreat variety of preparations, has long been the chief ingredient in quack remedies. It is thus vended under the form of tincture, drop, pow- der, pill, &c. And article of materia medica possessing such activity in some conditions of the living system, may be capable of producing 123 great and salutary changes. But in effecting these, certain premises and indications are to be attended to, to justify the exhibition : and the physician who does not give himself the trouble to consider these circumstances, may perform the. part of an executioner. Mercury being particularly hurtful where the stomach and bowels are very irritable, is forbid in gout and in the nervous. In those persons, fric- tions of the ointment lessen the danger. Hence it is improper in women and children ; in those subject to epilepsy, or other convul- sions ; and in every oner who may be liable to spasmodick complaints of anyform. In states of torpour and strength, it can be given with more safety : it i9 supposed to be the best re- medy in glandular obstruction, if the attendant debility does not contra-indicate its use. But it is top often to be observed, that those who make most free with the exhibition of mercury, are the least qualified to guard against its bad effects in improper cases. I resided a few years ago in a naval sea- port, where I was often consulted for stomach and nervous complaints, by ladies, the wives and relatives of officers, and my other friends 124 in the public service. Many of these female had been residents in warm climates. The great resemblance which the cases had to one another, excited no small degree of surprize at first, till I learned they had been all subjected to a similar mode of treatment. In shorf, they had been patients of a physician of exten- sive practice in the neighborhood, who pre- scribed mercury for every disease. INIost cf these women, among whom were some of great mental and personal accomplishments, had been kept for months or weeks under the influence of the medicine ; with their throats, mouths, and tongues so swoln and excoriated, and the teeth so loose, as to confine them to a diet of slops. Those who had no stomach complaints when they began this treatment, found them come on after it ; and such as had been nervous and dyspeptick before, felt all their ailments aggravated. This physician not satisfied with the milder preparations, made a common remedy of hydrar. mur. A practice not unlike to what I have just related, made some noise in our navy during the late war. A physician on a foreign sta- tion, took it into his head that all modem dis- 125 eases originated from Syphilis. It was in vain that officers and seamen pleaded innocence : if they were unconscious of receiving infection themselves, they wTere told it must come from their parents, sometimes to many generations back. Few men could answer for their purity on these occasions : a mercurial course was therefore directed ; not for days or weeks, but for years ; for there was no safety but in continuing it at intervals through life. A medicine of the kind, employed on such terms, could not fail to do harm : some of the most unfortunate stomach affections which ever came under my care, owed their cause to this treatment; a few valuable men were brought to the grave by it, in the circle of my own ac- quaintance, where I suspected a schirrous py- lorus. Mercury exhibited in quantity, either by the mouth or by friction, very quickly excites an artificial fever, ushered in by chills, shiver- ing, and a hot stage. The pulse becomes frequent, at first full, but latteily weaker and quicker: want of appetite, nausea, and often vomiting, commence ; restlessness and night sweats supervene ; the body bears the cold ?ir L 2 126 ill; head-ache ; foetid breath ; the bowels are commonly oppressed with flatulence, severe twitches, purging, tenesmus, and even bloody stools ; to these symptoms, debility and ema- ciation succeed; the tongue, mouth and throat, inflame, swell, grow painful, and ulcerate, and the saliva is poured forth in a continual stream. During the effects of mercury on the body, the mind becomes irritable and unequal, but generally low spirited ; and after some- time, exhibits all those feelings, usually called nervous, inducing the hysterick affection, con- vulsions, and frequently the epileptick parox- ysm itself. It is therefore plain, that in the nervous temperament, all the phenomena now described, must appear with greater violence, as is observed in children and women, and in all who have weak bowels. The constitutions of children, in point of debility and irritability, approach to the female habit of body : the nervous power is liable to irregular motions ; easily affected by stimuli, and prone to convulsions. Hence mercury is apt to have dangerous effects upon them. With some medical people, as well as parents, this medicine is much employed as a vermi- 127 fuge : it has the advantage of being easily dis- guised, and if joined with a purgative, acts very briskly, and commonly brings away ma- ny of those vermin. But worms being only the consequence of a weak condition of bow- els, mercury, instead of correcting the cause, tends still more to debilitate the first passages when continued long, and lays the foundation for much ill health. I shall touch on this part further, in the treatment, as being intimately connected with my inquiry. In the mean time, I cannot sufficiently reprobate the con- duct of some persons in high life, who permit their names to be published in the handbills and advertisements of an illiterate quack, whose worm medicine is known to be mercu- ry, and liable to be given in very unequal do- ses, from the nature of the composition. About twenty years ago, two children of a friend of mine, took calomel from the family apothecary, for worms. The exact dose in which it was given I do not recollect; but the motions which it produced were innumerable. The family, during this process, were all at once alarmed, by the singular noise which the children made in their throats, with an unusual I 123 change of countenance and cast of the eyes ; which were quicklv followed by violent agita- tions and contortions of body, and lastly con- vulsions. In a few day3 these odd complaints disappeared, as the effects of the mercury abated: but the apothecary thought proper to repeat the calomel, obstinately contending that the fits were mere affectation, and not to be imputed to the medicine. The same effects however appeared after the second exhibition ; the evacuations were not less profuse and debi- litating, and the convulsions more frequent and severe. The moment one child was seized, the other was affected in like manner : so cer- tain was this kind of nervous sympathy, that there was a necessity for separating them, that they might not see or hear one another, and the fits went gradually off. One of them, a young lady, has been long a martyr to the most painful nervous eomplaints; and I can* not help thinking that much of this indisposi- tion was brought on by this vermifuge pro- cess. This mineral, after long use, besides ex- hausting the nervous energy, is known to af- fect the bones, and render them friable, just 129 as thev are found in rickets and old' age. A poison so subtle and active, thus consumes the vigour of body, and brings on premature senility. Those hidious effects are most pro- bably produced by the mercurial oxide first depraving the digestive powers, preventing assimilation of the chyle, and vitiating sangui- fication. On the whole, while mercury is capable of great good in the hands of the sagacious physician, when indiscriminately used by the ignorant of the profession it must do incalculable mischief. Bitters and aromaticks.—These arti- cles, when well timed, and directed with judge- ment, are valuable medicines in treating the diseases now under discussion. But like many of the other good things in life, are too often misapplied, and thus tend to confirm what they were meant to remove. I here use the term bitters in a greater latitude than is commonly done by writers on the materia medica, and include the celebrated Peruvian bark, and those substances which are allied to it, either in their effects or sensible qualities. Their office is to strengthen and stimulate. The cinchona (bark) itself is a medicine, now 130 a days in such general use, that there are few diseases to be met with in this country, w here it is not given at one period or another ; and it is to be found in every family medicine chest. An article possessing so much active quality in the human body, as to be capabU of suspending a severe ague fit, cannot be deemed a passive remedy, or what ought to be trusted in every person's hands. The phar- macutical treatment of cinchona is also wor- thy of consideration. I refer the reader to the comparable work, called the New Edinburgh ispensatory, by Dr. Duncan, junior. When July prepared, and suited to the condition of the stomach, its powers are invaluable; where- as administered in an improper form, it may have most baneful effects. It is recommended by some authors in doses so large, that in our practice were never seen expedient, or the stomach capable of retaining them. It is therefore to be suspected, that in certain dis- eases, pain, sickness, and vomiting super- vene its use, and that the effects of oppression about the stomach after a large dose, have not unfrequently brought on such a degree of tor- pour, as to terminate in death. On the coast 131 of Africa, where intermittents assume a more aggravated form than ever seen in Europe, I always found, upon an avarage, six drams of the powder given in eight doses, for four hours before the accession of the cold stage, at half an hour's interval, have more effect than eighteen drams given in twenty-four hours before the .fit. This was a great saving of the medicine, which is worthy of attention by naval or military surgeons on foreign sta- tions. Nothing in the practice of physick can be more irksome than to see a poor patient strug- gling to get over his bitter potion ; it ought at least to caution the physician against an unne- cessary allowance of medicine, for it must often defeat its purpose. When convalescent myself of fever in the West Indies, I was or- dered a dose of bark every hour; but such was my aversion to the medicine, and such the irritable state of my stomach, that the fourth dose always brought on sickness and vomiting, t>y which the whole was disgorged. I tried from day to day, to go on with my quantum; it was all in vain ; and at last the very sight of •bark made me sick. If such a school cannot 132 teach a physician sympathy, I know not how it is to be done. Those articles, more strictly called bitters, require still more caution in the exhibition, as possessing the power of exhausting the excita- bility of the stomach by long use. They im- pede fermentation in the prima via;, and cor- rect acidity ; these they effect chemically. When long continued, as in the history of the Portland powder for gout, they are said to produce palsy and dropsy, and every species of nervous debility. There must therefore be a period when the good effects cease, and which careful observers will mark. If bark and bitters are medicated by alcohol, in the form of tincture, it is obvious the hurtful effects, after a certain time, must be inevita- ble. The aromatic substances, among which may be reckoned all the spices and volatile oils used in either diet or medicine, by repetition become hurtful to the stomach, whether as condiments, with food, or to cover the disa- greeable flavour of some articles. These sub- stances have, therefore, a limited time to do good, that their use may not become habitual. 155 There is always something wrong in those stomachs which hanker after hot ingredients : when these persons are served with watery preparations of medicine, they complain that they are too cold, and disagree with them ; but the moment a spiritous tincture is substi- tuted, there is little danger of its being refused. It is the duty of every honest physician to re- sist those cravings of his patient, and to endea- vour all in his power to correct hurtful pro- pensities. Vegetable Acids.—It is a well known fact, how much these acids weaken the or- gans of digestion. They are often drank clandestinely by corpulent young womert, to correct obesity, that they may preserve their shape. This is always accomplished at the expence of health : cramps and pains of the stomach, morbid acidity, and eructations, bowel complaints, sallowness of complexion, nervous head-aches, fainting fits, amenorrhea, fluor albus, strangury, See. follow this prac- tice, and death frequently happens. All per- sons subject to indigestion, the gouty and hysterical, know well from experience, the bad effects of native vegetable acids. They M 134 may be supposed to act directly on the fibre* of the stomach : but if they act chemically on the gastrick juice and bile, they cannot fail of vitiating the chyle, preventing the assimila* tion of the different intestinal juices, and thus depraving the nourishment. But it may also be supposed, if not in some degree certified, that in passing the glands of the mesentery, they cause obstruction and enlargement of these, give a disposition to scrophula, and otherwise injure the whole habit. Vegetable acids have thus a directly opposite tendency to the mineral acids, such as the sulphurick, muriatick, and nitrick, all of which have a share of reputation, in states of weakened dU gestion, Narcoticks.—These include ardent spl* rits, opium, and all those articles commonly called anodynes, hypnoticks, paregoricks, &c. such as lactuca, bang, belladonna, hyosciamus, laurus cerasus, cicuta, &c. Of the effects of ardent spirits, in producing stomach and ner- vous complaints, I have treated largely in my Essay on Drunkenness, to which I refer the reader.* All the articles now enumerated, * Second Edition. London, 1PG5. 133 act very much alike on the human body. Is small quantities, they induce vigor, activity and strength, and an increase of muscular pow- er throughout the frame ; at the same time are felt serenity, pleasure and courage of mind. In larger doses they bring on sleep, stupor and delirium ; and when carried to the utmost, quantity, insensibility, apoplexy and death. It is of little moment in this inquiry, whether narcoticks ought to be considered as directly or indirectly sedative. They are forbid in all inflammatory diseases, where they certainly do harm in the first stage : they generally occasion constipation but hyoscia- mus has a laxative quality. When long conti- nued, they are known to weaken the nervous system in a surprising degree ; disposing to amentia, epilepsy, palsy, tremours, convul- sions, melancholy, madness, &c. No sub- stances in nature more certainly injure the powers of digestion, and bring on all the se- vere symptoms of nervous infirmity. This effect of narcoticks, is most likely primarily derived from the nerves of the stomach, with which they come first in contact, and thence extended to the other viscera. Where there 136 is a predisposition, or hereditary nervous temperament, or gout, the permanent use of them is still more quickly hurtful : in such states of the body, they ought, like vinous spi- rits, never to be prescribed but from neces- sity. 'Opium, the noblest attribute of medicine, so calculated by its powers to sweeten life, and suspend pain, when all earthly comforts avail nothing, has its limits in doing good. It is a misfortune when it comes to be dispensed by injudicious hands; for it is often prescri- bed by the most ignorant, in diseases where it is forbid. The bodily complaints of the hu- man race, when enervated by luxury and re- finement, seem to produce more acute pain, at least the temperate man is observed to bear sickness with more patience and resignation, than those accustomed to indulgence. The spirits are apt to flag, as if the mind had no resting place. Opium alone gives relief, though it must feed the disease. Such per- sons seem to compound with their physician for sound nights and days of ease ; and if he does not comply, he must be changed. Hard is the task imposed on the medical attendant; 137 he must obey, or starve. The night draught thus becomes familiar in the family : the ser- vant goes to the apothecary for it with as little ceremony as he buys kitchen silt. He sees the shop boy count the drops into the phial, and when he gets home, narrates the composi- tion of the placebo to the cook and the nurse- maid. Not a domestick in the house but soon learns what a fine thing laudanum is ;— and master swears he can get no rest without it. If such things did not exist, how comes it that seven young women in this neighbor- hood, within the last three years, should have known that a large dose of this tincture will kill. Two of the number effected their pur- pose. I was called to visit another in con- junction with Mr. Elliot: she had swallowed t twelve drams of laudanum ; but I arrived be- fore it had been twenty minutes in her sto- mach, and by plentiful dilution with vinegar and water, followed by an active emetick, the bad effects were prevented. I remained in the house till I was certain that every drop of the opium was discharged, and she did well. It appeared that these poor girls had become M 2 138 the dupes of designing men, and called for death to end their sufferings. Thus the dose of opium concludes what was begun in the circulating library. A little more secrecy and discretion are certainly wanting in the ge- neral use of this dangerous narcotick. But there is reason to believe, that even medical men themselves, have of late, entered too easily into the indiscriminate use of opium. He must be a short-sighted physi- cian that does not calculate upon the ultimate effects of his prescription : it is a weak ex- cuse for getting quit of the importunities of a patient, by complying with an improper re- quest, that may afford* temporary ease, at the expence of permanent health. In the nervous temperament it is particularly hurtful. I am acquainted with numbers of ladies that feel such horror at taking it, as nothing can equal; and in every illness they may labour under, constantly warn the medical visitor about gi- ving it, as no disguise can make it agreeable to them. But, when opium happens to be soothing to weak nerved people, from their quick sensations, it is apt to be the more craved for, and converted into habit. The 139 langour and dejection which follow its opera- tion pave the way for the repetition of the dose, till general debility succeeds. In such constitutions, the exhibition of opium ought never to take place on slight occasions. Mid- wives, nurses, and other persons out of the medical profession, who dispense laudanum at random, ought to be solemnly warned against it. The opium-eaters in Turkey, are the most pitiable objects in society. Their squalid looks and emaciated bodies, after a long course of this narcotick, evince how fatal its use is to the digestive organs, and how it prevents the due assimilation of nourishment. On dissection, the same effects appear in the stomach, liver, and bowels, which follow a long course of ardent spirits. Like the dram drinker also, when deprived of his wonted cordial, they are languid, faintish, low-spirited, nervous, and feeble. Their limbs totter under them ; their heads and hands tremble, and the very wind is in danger of oversetting them. Their facul- ties seem exhausted, the memory fails, and the only remnant of intellect which they pos- sess, appears in the frightful accounts which 140 they give of their horrors, and the hypochon- driacal glooms with which they are infested. No form of disease exhibits existence under a more^deplorable shape than the opium eater and dram drinker. There is great reason for suspicion, that this drug is daily getting more iqto use as a cordial, and privately consumed by numbers of persons. It is well adapted, fiom its preparation in tincture, to be carried about, and drank at pleasure. Its exhilirating quality creates a momentary heaven for minds who find nothing but guilt and despair in their own reflections: hence it has grown so general in fashionable circles. I am also of opinion that many sudden deaths are in the present times, occasioned by this drug, without excit- ing the least suspicion of its being taken. Those who accustonMhemselves to the narco- tick article called bang, in the East Indies and in the Turkish dominions, are said to perish under diseases similar to those of the opium eater. Tobacco is another narcotic in common use. Persons who are in the habit of chewing, snuffing, or smoking this Indian leaf, are not aware, that a few grains of it taken into the 141 storciack, cause sudden death. Nay, the smoke of it injected' into the rectum, has fre- quently proved fatal. It powerfully acts on the nervous system, destroys the sensibility of the stomach; and it is observed that those who devour it in great quantity, die of apoplexy, palsy, and dropsy. v Poisons.—All kinds of poison, so called, whether taken from the animal, vegetable, or mineral kingdom, if not immediately fatal, weaken or destroy the functions of the sto- mach, derange the nervous system, and bring on nervous diseases ; so certainly are the di- gestive organs the first to suffer, and stand from their office as centinels of life. Bleeding.—Numbers of persons labour- ing under nervous debilities, attribute the first appearance of their malady to large bleedings, or evacuations of blood from other causes. No fact is better known to the medical ob- server than that frequent convulsions are a common consequence of the large loss of blood. The nice connection between the cir- culating and nervous systems, cannot be well explained, but they act reciprocally on one an- other. It is equally clearly ascertained, that 142 men or women of the nervous temperament,, bear the loss of blood ill. Indeed it seldom or never happens, that their diseases indicate the practice: when done, it has commonly been through the ignorance of some stupid attendant. Abortions, and severe floodings after child-birth, are often traced as the be- ginning of painful and lingering nervous af- fections, that sometimes remain for life. Reflections on Medicines.—Physicians having wisely drawn the line between medi- cine and diet, the former can only be indicated in some of the diseased conditions of the body. There are a multitude of articles in materia medica, beyond what I have thought proper to animadvert on here, possessing equal activity to those enumerated. Some of these may be supposed to have a chemical agency on both the solids and fluids; while others appear to act more immediately on our sentient parts. It is evident, then, from the most ac- curate observations, that such substances ought to be exhibited with great caution, and their operations watched with the most punc- tual attention. Many of the metallick salts, the mineral acids, all the alcalis, some of the 143 tieutral salts, and many simple remedies taken from the vegetable kingdom, are of this des- cription. The nicest study of the physician must be that at the bed side of his patient; in observing the phenomena of disease; de- veloping the genius of a distemper ; unfolding peculiarities of constitution ; selecting medi- cines for these indications of cure, and dis- cerning [their action and appreciating their power, that he may be enabled to proceed on the same plan of treatment, or adopt another* Nature has endowed so few minds with that „ superior intelligence of being equal to this task, that we cannot be surprized when told, that medicine is still in many respects "a conjectural art." Where men do not all possess the came sagacity, cultivated talents, and ex- tensive acquirements, they must think and reason differently, on subjects which bear no resemblance to other human pursuits ; and concerning which no appeal can be made, without overstepping the bounds which divine Providence has prescribed for the ingenuity of mankind. 144 CHAPTER IV. Influence cf these diseases on the character of nations, and on Jomeitick happiness, IT is a fact fully confirmed in the history of mankind, that a similarity-of manners has ma'*.Led all nations, in their progress from riidtness to refinement; in their rise and in their decline. An infant state is commonly poor : but from intercourse with its neigh- tours, it learns the advantages of a change of produce and commodities ; and this traffick soon gives spring to ingenuity, and birth to adventure. Amidst its articles of utility, it also imports some that are showy and elegant: the arts of inventing new sources of gain, be- ing natural to the human mind, gradually ex- tend ; till luxury in all its shapes, appears in the manners amusements, and government of every commer ial people The ai ms of impe- rial Rome si ued the world ; and made that city the emj-.-ium of wealth and grandeur, 145 drawn from all other nations. Luxury, crimes and irreligion, were soon the consequences of power over-grown, and riches unbounded. And this haughty, wicked people, when they had lost their moral virtue and dignity, and with these, their physical strength, became a prey to barbarous hordes ; who, undebauched by refined pleasures, found the enervated Ro- mans an easy conquest. Let Great Britain look to this example. The East and West In- dies at this moment, are St theatre of oppres- sion and slavery, to gorge her with commer- cial wealth ; and a district of Africa, larger than Europe, is made a field of blood, to pur- chase the natives for cultivating her colonies, whose produce only tends to weaken "her man- ly character, and overwhelm her with nervous infirmities ! The rise and fall of a large commercial town, may be taken as an example of a nation. From a few fishermen's huts, on some river or arm of the sea, it gradually extends and improves, till the exchange for business, and the theatre for amusement, become its orna- ments. A narrow port is by degrees, widen- ed into a capacious harbour: and the ware- 146 Louse, manufactory, and shop, increase in pro- portion, till wealth and elegance dazzle in eve- ry lane and alley. The coffee-house, the inn, and the tavern, grow necessary appendages to business and pleasure : the morning begins with a bargain, and the evening closes with a banquet. Then the rout commences, to teach the young the arts of gaming ; and the mid- night masquerade initiates them into the wiles of intrigue. The riot disturbs sleep; the drunkard is seen staggering home, in dan- ger of robbery and death ; and the woman of the town, deserted by her destroyer, is seek- ing reprisals, and looking for prey in the streets. Now the hospital and bedlam appear :>n the suburbs ; the first to receive the poor, sick, and lame ; and the other to confine the more wretched in mind. The physician and apothecary are seen gliding in their chariot3, v, ith retinues sometimes not much like men %vho are conversant with human affliction, and enriched by the luxuries and vices of their fellow mortals. Morals and health are alike committed in this vortex of wealth and dissi- pation. The industrious man who began the voild with a capital of fifty pounds, who ros« ur at five, and went to bed at nine, who dined on a plain joint and pudding, and drank nothing stronger than table beer, does not find a for- tune of fifty thousand pounds exempt him from gout and nervous torments. A crowd- ed population multiplies all contagious mala- dies, but especially fevers of the worst kind. Fashionable pleasures such as towns only ex- emplify, are a fruitful source of weakness and pain: and drunkenness and mercurial cour- ses, of themselves, produce more wretched- ness and disorders, than the whole natural in- firmities of life. Under these circumstances, the human frame must degenerate in both bo- dy and mind, as we see in modern Egypt, Turkey and Italy. Thus flourishes the com- mercial town or state, till its wealth and effe- minacy weigh it down ; when it falls like Tyre or Alexandria, like Corinth and Car- thage, to be a retreat to robbers, and a den to wild beasts. As we analyze the manners of society, and scrutinize those causes which lead to the dis- eases of which we treat, we observe their ope- ration and influence to be very general, and daily increasing. Commercial Britain, en- 143 riched by manufacture and colonial wealth, when compared with her barbarous state does not exhibit a nobler spirit of independence, or show more fortitude in opposing French inva- sion, than what was done nineteen hundred years ago, by our forefathers, in repelling the Roman legions. Our invaders were then obliged to build strong walls and ramparts to shelter them from the Britons :* but modern Britons have erected Martello towers, projec- ted the inundation of Essex, and hoarded up the current gold coin, as tokens of being afraid of the French. These alarms are to be consi- dered as so many symptoms of a nervous tem- perament appearing in our national character. Britain had no ships to oppose the landing of Julius Caesar ; but at this moment she has a navy capable of fighting the whole fleets of Europe united ; yet she trembles at a flotilla of cock-boats. It is that puddle of corrup- tion, the Stock Exchange; that Delphi of Plutus, where stock-brokers pay their vows, and expound prophecies, that has filled th; nation with degenerate fears, apprehension, * The walls of Adrian and Severus. 149 and hypochondriackism. Europe has been saved by the British navy from the fangs of French tyranny ; yet shameful to be told, af- ter the fleets of France have been annihilated, we are now to be assailed by three thousand wherries, manned with blue devils.* If I am altogether correct in saying, that the nervous temperament is hereditary, and therefore the diseases which depend upon it, liable to be extended to the offspring, they must multiply in prodigious proportion. They appear in the present age to have acquired that growth, which nothing but a general re- volution in all ranks of society can check. I may be told that these diseases are not very dangerous, and very seldom produce death ; * The gentlemen of the Stock Exchange, as they dcuomitate themselves, are projecting great things from the conquest of Buenoes Ayres. Spain, humbled, degraded, pillaged, by an imperial cut-throat, is almost blotted out of the map of Europe ; which she owes to the gold and silver brought from the new world. Yet these gentlemen seem to entertain no fears for the like fate happening to Great Britain. Such is the patriot- ism of money lenders! N 2 150 and it may be added, the bills of mortality do not justify my conclusions. These argu- ments are easily answered. It is true, death is seldom put down to nervous disorders : but if constant pain, mental disquietude, and ap- prehension of dying, are to be considered as evils in this stage of existence, then are ner- vous afflictions to be held as the chief cause of them. And it is to be remembered, that the most frightful part of the catalogue of dis- eases, such as apoplexy, palsy, madness, me- lancholy, epilepsy, convulsions, cholick, ili- ack, passion, atrophy and dropsy, are often ushered in by nervous affection, before they assume their own character and shape. Phy- sickal strength of body cannot be long pre- served under enervating modes of living: the stature and the mind must both diminish and degenerate. The poet says, fortes creantur fortibus et bonis; and very aptly adds, ----nee imbellem feroces, Progenerant aquilx columbam. Hor. V An eminent senator, Sir John Sinclair, has lately made some noble attempts to rcge- 151 nerate the physical strength of the country, by recalling mankind to agricultural life. His institution of a society for that purpose, under the authority of parliament, has alread}? had considerable effect. Many noblemen and gen- tlemen, of great landed property, have second- ed these patriotick views, and turned their at- tention to this national object: a spirit of im- provement has appeared in every county, and is daily increasing. No man who possesses the smallest spark of love for his country, but must wish full success to the undertaking. No truth in political economy is better proved, than that a nation of sedentary people, can never be a nation of heroes. We might in- deed preserve all our manufacturing establish- ments, and most of the fine arts, during the degeneracy of physical courage: but could an army of man-milliners defend the British islands against the ruffians of Bonaparte ?* The puny inhabitants of Italy and Indostan, are finer spinners of silk and cotton than Eng- lishmen, because they are strangers to all the masculine virtues. Let us therefore beware * Non Ids juventus crta parentibus, &c. Hor. 152 Tiow we extol too much the effeminate labours of the spindle and the loom. A commercial people merely, can never be an independent nation. They owe to foreigners the consump- tion of their manufactures ; and when these chuse to do without them, or to buy them else- where, such a people must become bankrupts in finance. The glory and security of the United Kingdom, must be to blend these pur- suits, agriculture and commerce, in the na- tional character. From the imperfect state of the medical histories, which have come to us, from the early ages of the world, we are left much in the dark, how far luxurious living and effemi- nate customs, affected the health of nations. We are told of their vices and debaucheries arising to excess ; and these seem to have ge- nerally been forerunners of their fall and de- cline. When the form of republican govern- ment in Rome, yielded to the tyranny of the Csesars, with it the republican virtues gave way to the vices of courts ; and the Romans soon after lost their character for military prowess. It is therefore but fair to infer, that the faculties of soul, and the vigour of body, 150 underwent immediate changes ; and that a train of diseases, of a peculiar cast, sprung up among this debased people. Hence the mo- dern enervated inhabitant of Italy must be very unlike the ancient warlike Roman. The youth of the one is spent in learning musick, painting and frippery: the other was early trained to bear fatigue, hunger, thirst, run- ning, leaping, swimming, &c. Diseases of the same class, could not therefore exist, in. constitutions so different in habit and predis- position. The rural life also occupied a con- siderable portion of time with the Roman worthies of the old republick. All the Latin classicks abound with beautiful eulogies on rustick manners, scenery, and recreation, par- ticularly Virgil, Horace, and Pliny the youn- ger. The greatest man whom modern ages have produced, George Washington, Esq. was of this school. How much nobler was it to retire from the command of a victorious army, after securing the independence of his coun- try, for the study of nature in his own farm, than to live in a city to learn excise laws, and squeeze taxes from industry, to pay profligate favourites, and unprofitable wars. How mean J5-i and contemptible the upstart emperour of France appears, when compared with this tru- ly christian hero, the friend and admiration of human kind ! The diseases of a labouring and active pea- santry, or of those of any condition of man- kind, exposed to the weather in all seasons, arc almost confined to the inflammatory class ; such as pleurisy, acute rheumatism, catarrh, cynanche, Sec. These depend on a vigorous vital power, a rigid fibre, and a florid dense blood : they are a directly opposite state of the system to what predisposes to nervous dis- eases. No kind of diet comes wrong to the stomach of a hale rustick ; the unleavened fc.« rinacious meal, or a draught of imperfectly fermented malt liquor, that would throw the dyspeptick and bilious citizen into a cholick, he takes down with impunity. He is also ca- pable of braving fatigue, privation of food and sleep, and tvery other hardship, in a manner that would soon destroy the town inhabitant. A nation that cannot recruit its soldiers from a robust and hardy peasantry, can never bring 155 into the field an army able to endure the tolls and adventures of actual war.* Amidst the general effeminacy of manners, that is rapidly consuming the manly spirit and l-hysical strength of this age, and what may ultimately annihilate all that is great in the character of Britons, it is somewhat consoling to observe, that the seamen of the navy, that bulwark of our liberties, will be the last of the community to feel the .effect of those enerva- ting customs. The naval officer and seaman embark in their profession while boys, before they can be acquainted with the softening arts of the day. Hardship, danger, and privation, are the lot of naval service.; to brave the wea- •iher, the season, and climate, is their delight and their duty ; which, fortunately for their country, grow into habit. Hence they have little enjoyment among the common amuse- ments of society; and feel that kind of life hang heavy upon them, that gives no birth to action and enterprize. It is true a species of nervous disease did make its appearance du- * See Dr. Robert Jackson, the army physician, , s ■tiiiri subject. 155 iing the late war. It occurred among both officers and men ; but was by no means a ge- neral malady.* The hard duty of a stupid blockade, had a chief share in its production. Statesmen, I believe, seldom or never read the medical history of fleets and armies. They are afraid that such gloomy narratives would alarm conscience, and bring on fits of hypOchondriackism.f Yet by these means, they might be made wiser ministers, if not bet- ter men. The practice of blockade has crept much into our naval system of late ; yet it was abhorred by Howe and Nelson, as inconsistent * Med. Nautica, vol. 2. f The fate of the cow-pock inoculation in this coun- try, is a proof of the indifference of politicians to the y.iv icvcvnent of the health and si.fcty of the communi- ty. It has been said, that the late minister refused to become a member of the society for encouraging vacci- nation : and his predecessor, the son of a j hysician, opposed the ^ift of 20,000! to the immortal ruthmir of this matchless discovery, so that the grant vas only 10,0001. The preccr.t ministers, it is to be hoped, will retrieve the credit of the nation, by bestowing the me- rited honours ar.d rewards due to Dr. Jenner. See also the fate of this dLcnyery in a branch of publick service. Med. ¥d'i:. vol. J. 15,' with the genius of our seamanship. But, tho' it may be conducted with ease in the equal weather between the tropicks, it can never be effective in the stormy seasons of European seas. Such a mode of service is calculated to please underwriters and stock brokers ; but it can never be acceptable to the officer and sea- man. A-duty so severe, without variety to give spring to adventure, benumbs the facul- ties, exhausts the bodily powers, and in habits predisposed, brings on nervous irritability that shortens the span of life. It has been gravely asserted, and with much probability of truth, that during the reign of terrour in France, in the late revolu- tion, a period marked by fury and blood be- yond whatever was known in a civilized coun- try, all diseases, usually called nervous, low spirits, or hypochondriackism, quickly disap- peared. These diseases are so nearly connec- ted with the tenor of the mind, that great com- motions in the moral world, may both induce and remove them. But if, as we contend, they are chiefly the offspring of a life of sloth and inaction, violent popular tumults, that rouse anarch}' and ferocious passions, and let loose o !58 the furies among mankind, cannot fail of ma- king strong impressions on the timid and des- ponding. AH physicians conversant with these distempers, are aware that a correspon- ding train of thought attends the bodily disor- der ; and that it is a preliminary step to the cure, to infuse activity of mind, so as to force new ideas on the patient. We have heard of a fit of the gout being instantly cured by the alarm of fire ; and the person confined, throw- ing his crutches away to escape from the dan- ger. Nervous persons in different families, have been suddenly relieved by unexpected good fortune coming upon their near relatives j and the indisposition has again recurred by the return of a fresh disaster. The South Sea scheme of 1720, that bub- ble of commercial speculation, gives a curious example of the English character. It was re- marked at that time, that more instances of madness appeared, than at any former period. In short, numbers became maniacks, from the sudden wealth which fell to them; these were probably of the nervous temperament. The transition was too great and quick for the sensibility of particular constitutions. This 159 scheme having soon-failed, it is likely that hypochondriackism and low spirits, would succeed to an equally sudden reverse of for- tune ; but of this we are not told. A naval officer, while abroad in the late war, received a letter from his sister, telling him, that his ticket in the lottery had come up a prize of 20,000/. He was so elated with the news, that he became instantly delirious ; leaped from a wardroom window into the sea, and was drowned. The Athenian soldier, who ran to the city covered with dust and blood, to announce the victory of Marathon, was so overpowered at the event, that he could only call out, " Rejoice with the victors" and immediately expired. In like manner the Roman mother died suddenly, on hearing that her son had survived the battle of Cannae. It is probable all these persons were of the nervous temperament, from being subject to such violent emotions. Bad news, such as the death of wives and husbands, or children, however suddenly told, or happening unex- pectedly, do .iot seem to operate like excessive joy. Grief is slow in producing derangement of mind ; and is nearer to what we call the 160 mild delirium: while the frenzy of joy par- takes more of the delirium ferox. I have ob- served something like temporary insanity, in several officers, who had, at once been ele- vated from extreme poverty to a fortune, by prize-money. Men who have been wealthy and afterwards reduced to indigence, often sink into despondency and low spirits. But it is also true, that persons who have,unex- pectedly received great riches or legacies, are apt to turn hypochondriackal, by being lulled into ease and security, and having no longer cause for action and enterprize. I have known habitual drunkenness in a family, that brought on some of the most afflicting nervous symp- toms, completely overcome on a signal mis- fortune befalling a brother ; and nothing be- yond water used afterwards. Such a fact totally disproves the reasoning of those physi- cians, who tell us it is dangerous to subtract the stimulus all at once. The mind that is stabL-, by a firm nervous system, is little shook by the incidents of life : whereas the fickle constitution of nerves bears unequally every vicissitude ; but sustains sorrow and disap- pointment, better than joy and good fortune- 161 Thus the moral propensities are to be learned from the physickal habit; and the peculiar genius of diseases, unfolded by the passions of the individual. The nervous temperament, abstractly con- sidered, is often the seat of dispositions, that appear in two extremes ; and giving birth to passions of the most opposite kind. Under the government of a bad heart, it is fero- ciously cruel, or abjectly timid. When men possessing those traits of character, happen to be armed with power, they become the scourges and butchers of mankind. Such, we suspect to have been the temperament of all those tyrants, whose reigns have been marked by murder and outrage in the history of na- tions. The present ruler of a neighbouring people, appears to be a man answering to this description. Pie is said to be subject, at times, to the deepest hypochondriackal glooms; and while under their influence, his temper exem- plifies more of the demon than the human be- ing. Jealous of his personal safety, even to timidity, because he is aware that his plans of ambition are to be effected by bloodj and ac- complished by perfidy, he knows that he can- o 2 162 not be beloved. Through slaughter and fraud, he has waded to a throne : and his obtaining the sceptre, was the signal to shut the gates of mercy against his species. A stranger to every domestick enjoyment ; unsusceptible of the tender passion ; and aloof from all the temperate and soothing pleasures, which sweeten the slumbers of a good man in power and prosperity, this arch tyrant is said nev r to sleep two nights in the same bed, from the dread of assassination. When any sudden disaster befals his projects, without a single virtue to cheer reflection, he becomes his own tormentor: his bowels are wrung with spasms; the biliary ducts partake of the commotion ; and a jaundiced hue of the eye, indicates to the spectator, the features of some devil that has usurped the human form. Under this sombre cast of countenance, his vindictive passions brood over crimes, and hatch plots, that he may find victims to glut his desire for blood. In such moods, he sends to the guillo- tine, incarcerates, or proscribes the devoted loyalists of France ; anticipates in their fate the doom of Englishmen ; and feels in minia- ture that gratification, which he longs to ex- 163 perience by the invasion of Great Britain. Historv tells us of bad men that were born with teeth in their jaws, and of others, whose hearts were found hairy: such relations are amiable, if they even arose from the folly of superstition, as they imply the hidqpusness and detestation of vice. And future ages may inquire with avidity, for the puysiologickal structure of that breast that was so superla- tively steeled, and possessed passions so tran- scendently cruel above what is recorded of the common destroyers'of mankind. But it must be unfortunate for any nation to be governed by a man of capricious tem- per, even though his passions are gentle and mild. A nervous statesman could not easily divest his publick measures of some portion of his constitutional dispositions. He would at times view things through a false medium : and by judging from mistaken premises, would conduct the business of government with im- becility and supineness, and bring it into con- tempt. Every plan he devised, would partake of the mood he happened to be in at the mo- ment : it would be liable to defeat, and exposed to opposition ; in hazard of being divulged 164 before execution, and open to derision. The morbid sensibility of a deluded hypochondri- ack, might alarm a people by imaginary dan- gers : and in the season of disaster, might bring ruin on affairs by irresolution and des- pondency. By such men nations have beeu plunged into unnecessary wars ; and inglo- rious peace concluded, when advantageous terms might have been obtained. Men endued with an exquisitely nervous temperament, ought to be banished from the councils of all sovereigns, however respectable their talents ; for consistency and fortitude^ire incompatible with their physickal character. In the medical profession, the nervous temperament might also so affect the practice of the physician, as to render it feeble, fluctuat- ing and irresolute. Diseases often take most unaccountable turns, not to be foreseen or prevented by human abilities. Such sudden changes not only require firmness of mind and address, on the part of the attending physi- cian; but his conduct and example may so affect the patient, as to bring on a fatal des- pondency. Hence the value of confidence in the medical friend. To a sick person, who 165 things himself in danger, nothing is-so dis- tressing, as to behold fear and distrust in the countenance and deportment of his medical director: a nervous frame is therefore very inadequate to some situations of this office. But in the. comrnon transactions of life* nervous people are difficult to be managed. Their tempers are fickle, their spirits unequal, and their attachments equivocal. In business they are indecisive, unsteady, and impractica- ble. Their friendships are often puerilish, and their resentments unmanly. Amidst do- mestick connections, they are apt to teaze their relatives by the observance of trifles ; while concerns of importance are frequently degraded by an ill-timed levity. Much of their time therefore is spent in making conces- sions to others for the inordinate ebullitions of passion ; or in torturing themselves by groundless fears, or imaginary affronts. At one moment you find them obsequious and compliant, grateful for correction, and gentle on being reminded of their duty. But this even tenour seldom lasts long ; and they grow impatient of contradiction, and furious from restraint. These transitions are commonly 155 sudden ; the same wavering and capricious principle of action appears to direct alike the healthful and the morbid state. We behold them one day taking leave of their friends, with all the solemnity and earnestness of dy- ing men ; and in imagination suffering worse than death : while on the next, they will be seen plunged into dissipation, fascinated with pleasure, and attending every fashionable a- musement. On the other hand, the nervous tempera- ment is often found to be the soil of numerous virtues : the noblest feelings are cherished here. Sensibility to excess marks the consti- tution ; and affliction cannot address it with- out meeting its sympathy. It is this degree of feeling that too often makes it the sport and victim of passion. It loves and hates beyond bound. Hence those corroding sorrows, which sometimes overtake the most tender of all attachments, and which ultimately bring the possessor to the grave. In adverse cir- cumstances nervous people easily despond ; and sink under misfortunes, which if opposed by patience and firmness might be happily overcome. In this temperament of the sen- 167 tient system, a genius for the elegant arts chiefly originates. The poet, painter, and musician, may be justly styled genus irritable vatum. We here meet with the whole eccen- tricities of superiour endowments, often blen- ded with the most abject pursuits : sublimity and debasement frequently mixed in the same character. Cheyne, in his English Malady, facetiously remarks : " I seldom ever observ- " ed a heavy, dull, earthy, clod-pated clown, " much troubled with nervous disorders, or " at least, not to any eminent degree ; and I " scarcely believe the thing possible, from the 14 animal economy and the present laws of na- " ture___p. 180. On the whole, the influence of these dis- eases is often great on national character and domestick happiness. When wealth and lux- ury arrive at a certain pitch in any country, mankind cannot remain long stationary in mental qualifications or corporeal strength. Domestick peace is first invaded by asperity of temper and turbulent passions. Vices and diseases are close attendants on riches and high living. All these gradually extend among the community ; and the circle widens, 168 till it engulphs a whole people ; when polished society may be said to bring on its own dotage, and to dig its own grave ! 169 CHAPTER V. History and progress cf these diseases, A METHODICAL history of these dis- eases, at least a narrative of the symptoms as they appear in succession, is almost impossi- ble. They assume such variety in form and manner, in different persons, that we look in vain for regular order. The only thing cer- tain and peculiar in their character, is predis- position ; which may be divided into heredita- ry and acquired. 1. By hereditary predisposition is to be understood, an original conformation of body, transmitted from the parent to the offspring ; by reason of which, when particular exciting causes are applied, a similar train of morbid phenomena takes place. A predisposition may therefore appear long before any symptom of actual disease has shewn itself: as in the phthi- sicnlly disposed, a person will be easily affec- ted by weather and sudden changes of tempe- r 170 rature ; and on slight occasions, liable to cough, hoarseness, tightness or stitches of the breast, &c. The hereditary disposition to the diseases in question, may be marked in the first stages of infancy in many cases; in others not to a later period., or till particular causes bring forth the latent peculiarity. The child born of nervous parents, that is to say, per- sons of weak digestive organs, and irritable nervous system, subject to bilious and spas- modick complaints, &c. will at the breast, be very liable to bowel affections, such as cardial- gia, flatulence, constipation, or diarrhoea, gripes, yellow gum or jaundice, &c. These will be apt to come on from slight occasions* as when the milk of the nurse is affected, ei- ther by her passions or improprieties of diet, or when any thing has entered its food that is difficult of solution in the stomach. These causes will-frequently operate with such effect, and to such a degree, as to induce convulsions and death. As the child grows up, the tendency to these complaints will be more perceptible on slight deviations from its regular modes of living. If it meets with badly fermented 171 bread, heavy pudding, eats too freely of fruit, sweetmeats, pye-crust, all kinds of pastry, pound cake ; or drinks of cyder, perry, beer, wine, punch, &c. the stomach and bowels will be quickly disordered. At the same time, a peevishness and fretfulness of temper will ap- pear, extreme irritability, want of sleep, sleep disturbed, with other nervous symptomsjtillthe offending cause has been corrected in the firaC passages. In some of the diseases of infancy, such a child will suffer more than other children. At the teething period, it will be more likely to be seized with bowel disorders and convul- sions : in the eruptive fever of the small pox, it will be more prone to these fits : and in the hooping cough, as being a spasmodick disease, the nervous infant will be a severe sufferer. Frights of all kinds, that ruffle the temper, and impatience under bodily pain, will be attended with irritable passions. Worms are the con- sequence of weak bowels and disordered di- gestion ; a child of this description will, there- fore be much troubled with worms, and gene- rally their most troublesome symptoms.— These symptoms will sometimes put on all 172 the appearance of a confirmed hydrccephalut interims, even to the last degree of strabismus* I have seen so many instances of recovery from this apparently hopeless state,that I am disposed to refer the whole to their intestinal vermin, or to some aggravated attack of sto- mach affection, depending on original nervous predisposition. At the age of puberty, if a female, it will be liable to be affected with that disease usu- ally called chlorosis ; which, besides so many symptoms of dyspepsia, combines with it the emansio mensium. The chorea, or St. Vitus's dance, also appears about this age : and in nu» merous cases which I have seen of both com- plaints, I am disposed to think, that they never occur without manifest predisposition, and are therefore to be considered rather as symptoms of the nervous temperament, than as distinct diseases. The changes which bow take place in the constitution, conjoined to the quick growth of the body at the same time, will ren- der this a most critical period. At this sea- son, the nervous woman is first affected with hystericks ; these added to many painful symptoms of increased irritability, will be agt 173 to recur at distinct intervals, through life, par- ticularly if unmarried. Extreme delicacy of stomach, dyspeptick affections, and what arc called bilious, dysuria, leucorrhcea, hemicra- rvia, &c. with other nervous signs, will be the lot of this hereditary predisposition. The female that is born of gouty parents, comes entirely within this description. The fact is notorious, that what is called regular gout, or gout shewing itself in the extremities of the body, seldom attacks the fair sex : and when it happens the woman is marked by a more masculine form, or other external signs indicating this peculiarity. But even this will not explain why the female is so seldom affec- ted with arthritick inflammation. Something may perhaps be sought in the generative fa- culty : the castrates are said to be exempt from gout : regular gout is very rare before the age of puberty ; and all the women whom I have known subject to inflammatory gout, except one, had never borne children. Gout, in all its shapes, is preceded by stomach affec- tion j so also is the period. Again, the sto- mach recovers as the pain and inflammation fix in the joints; and if they prematurely re* p2 174 cede, the affection of stomach returns. It i j the same with the period: when one goes on properly, the other declines in due time : and if cold, passions of the mind, or other causes, bring on a sudden stoppage, all the complaint* of the digestive powers instantly recur. But as the dyspeptick symptoms which at- tend gout, are so much alike in both sexec, making allowance for the greater sensibility of the female, they strongly support the idea>, that the chylopoeietick viscera are the original seat of this disease ; and these the primary symptoms of gouty diathesis. The child* therefore who is born of arthritick parents^ has in its constitution what may be called the predisposition to nervous and bilious diseases* In infancy it is prone to all stomach and bowel complaints from slight causes, as have been described, and these will be its attendants through life. Even the man of the gouty fa- mily will not be exempt from this disposition to be dyspeptick and bilious, on every kind of excess or improper indulgence. In both sex- es, they show a stronger tendency, as they ap- pear early ; for that proves a weaker structure of the digestive powers, and greater dcbiluy m of frame ; just as gout is to be more dreaded in proportion to its attack at an early age. Thus the youngest votaries of Venus and Bac- chus will run greater hazards of immature gout, and premature decrepitude as a conse- quence. 1. The other division of predisposition to these diseases, is the acquired predisposition i or what may be brought on by causes which especially weaken the frame of nerves, and the chylopoeietkk organs. This predisposition may take root, even during the earliest stages of infancy, in children born of the healthiest parents. The effects of the milk of an un- wholesome nurse often lay this foundation. It may happen where the child is not suffi- ciently nourished ; where the nurse is much affected with the disorders herself: if she drinks too freely of spiritous or fermented li- quors, or is in the habit of taking opium, or other drugs. Bad lodgings ; impure air „ hot rooms ; chills from exposure to cold ;. wash- ing the infant in water too cold or too hot j want of cleanliness ; dosing it with hot things, whether spirits or aromaticks ; frequent opi- ates in any form to make it sleep ; deficient 176 exercise J sweetmeats ; frequent recourse to medicines, such as emeticks and purgatives, but particularly calomel : and if these articles are often repeated at any stage of childhood, without competently prescribed, they must infallibly debilitate the stomach and bowel*, and induce the diseases in question. To all these causes may be added, the effect which the furious passions of some women have on the infant they suckle. But even children at an early age, are not beyond the reach of mo- ral causes, particularly females, and these will often operate with great force on sensible minds. The girl whose health has been thus ruin- ed, by improper nursing in infancy, or bad treatment in childhood, will be apt to suffer at puberty, and at the change of life. At the for- mer period, violent hysterick and chloretick affections will commence, end health w^l be precarious for a length of time. Such a wo- man will be generally liable to sterility from constitutional infirmities ; to abortion in the early months, and to premature binhs : these will often happen from slight causes j and much danger will be encountered duriDg far- 177 turition and in' the puerperal state. Other diseases of equal delicacj', which are too often the bane of female life, will be the portion of such a woman. These girls acquire an inac- tive sedentary turn in early age, which is sel* dom overcome ; they seem to vegetate, rather than live, and but rarely reach to fifty years. When women of this kind of habit suckle their own offspring, or that of others, they much injure the health of the infant as well as them* selves: such children commonly die in great proportion under two years ; and if they sur* vrve that age, it is with indellible marks of a puny and vitiated constitution. Among the poor in large towns, the proportion of deaths in infancy is great, chiefly owing to vicious nursing; and much caused by that nervous weakness brought onby the use of tea and spiritous liquors^ The acquired predisposition is also the fre- quent effect of preceding diseases and confine- ment ; such as typhusrfever, and all the fevers of tropickal climates. \Luxurious living, and highly seasoned food, that weaken and exhaust the digestive powers : excess of animal plea- sure ; courses ©f active medicines long eon- 178 tinned; suckling the babe till weakness and emaciation take place; severe labours ; hae- morrhages ; disappointed love, revenge or ambition; confinement in impure air; want of exercise; intense thought; long protracted grief; frights; a long state of suspense in waiting the decision of some important event; the improper use of opium ; spiritous liquors, and other narcoticks ; poisons of every kind in small doses ; and in short, whatever greatly disturbs or debilitates the whole nervous sys- term and abdominal viscera. Wounds and injuries of the head, concus- sions of the brain, and whatever may induce effusion and compression, so as to weaken the organs of sense and motion, or render them unequal in their action, sometimes bring on a nervous temperament, or at least pave the way to these diseases. These incidents are com- mon enough among our seamen and soldiers, and now and then to be met with in private life.* • Convulsions in the form of epileptick fits, artu common enough after organick lesions of the brain-. They have been frequently relieved by the trepan, 1T9 Having now fully described the nature of predisposition under these forms, we are pre- pared to relate, what, in common language, /goes by the name of a nervous complaint, or a bilious attack; expressions frequently heard among all kinds of people. But without pre- disposition ia some degree, it is to be presum- ed, that no person has at once been severely afflicted with these diseases. The two kinds of predisposition which have been investi- gated, constitute what modern physicians have called the Nervous Temperament, for it is not mentioned by old writers. A person subject to.nervous or bilious com- plaints, has commonly some warning of an aggravation of the symptoms, or of an attack. Some uneven tenour of the spirits ; something to ruffle the temper or passions; or some irre- gularity in diet, most frequently precedes them. In the sex, these complaints, for the most part, commence near the period, and when not severe, decline with it. A frequent desire of micturition, or a profuse discharge of limpid urine very often ushers in the attack, in both sexes. The patient himself finds it difficult to d«« IjSi) tcribe his uneasy sensations, for want of lan- guage : he knows not with what symptom to begin, though he will answer the questions of the physician with sufficient correctness. The physician therefore, finds advantage in putting emeries to the patient, as a few leading ones will often rave both much embarrassment and conversation. The mind is irritable, fickle and apprehensive; at one moment, tenacious of impressions, suspicious and jealous of con- tradiction : at another, hurrying from one thing to another.; grave and gay by turns; with fits of crying, laughing and incoherent talking ; but seldom indulging in conversation that is unconnected with the consultation. The desire for food commonly fails; an un- pleasant taste is perceived, which excites fre- quent spitting; sickness at stomach sometimes comes on very suddenly, with vomiting of green sour mucus, or of bilious matter- What is thrown up is often found so acrid and corrosive as to excoriate the throat and mouth, and slightly tinge silver; the fauces and tongue have been blistered from this cause, so as to appear full of pimples, or little ulcers, that render mastication of the food painful, ta1 tmd deglutition impracticable. The bowels are generally irregular, either constipated or the contrary, and oppressed with flatulence. Acidity, eructations, and dyspncea, spasmo- dick twitches about the breast, back and loins, accompanying these feelings. It is often sur- prizing to see the degree of inflation of the stomach at this time ; coming on suddenly, and remaining for hours. The skin is dry, and constricted, or in profuse sweats ; the whole surface of the body unusually cold, or uncommonly hot by turns ; with vertigo, tre- mours, risings in the gullet, and vast depres- sion of spirits. The patients are extremely sensible to the changes of weather, and bear easterly winds ill. The countenance is commonly downcast and sallow ; and the white of the eye exhibits, more or less, a bilious tinge. Few dyspep- ticjc persons have at all times a clear com- plexion ; indeed the looks are a sure criterion to judge of the habit. This suffusion of bile, sometimes amounts \p real jaundice, transito- ry, or more p that is to correct the predisposition. I have also seen a considerable number of cases of nervous affection, with all the signs which are said to'mark angina pectoris. This 189 ffomplaint has been thought to accompany par- ticular organick affections of the heart, and large blood vessels ; some of these I have seen, and they proved fatal. Of this kind was the case of the late captain Fisher, of the Pow- erful. But these organick derangements could not be the cause of the symptoms, in ca- ses which quickly recovered under appropriate treatment. Two of these I have met with in Newcastle. I cannot therefore help being of opinion that the anomolous form of the dis- eases, under discussion, renders it very proba- ble, that they have often given cause for unne- cessary alarm, as resembling what has been styled angina pectoris. It is not easy to combat the fancies and ap- prehensions of nervous people, when under strong paroxysms of their disease ; while these last, they are to be considered as aliena- tions of mind, and treated accordingly. In some situations of this kind, the flatu- lence is unusually troublesome, and so fluctua- ting in its movements over the abdomen, that the sensation of air or wind rising upwards to the brain, is among the most solemn beliefs of the patient. This fanciful idea has given birth 190 to the phrase vapours, a name for weak nerves* These vapours are therefore said to generate every thing in the brain that is terriflck or ri- diculous. Hence blue-devils, ghosts, and hob' goblins, have been conjured up to the affright- ed imagination of the patient; and bad men are said to suffer under their influence, tor- ments compared with the pains of heU : so faithful and certain are the admonitions of conscience ! Sleep disturbed and harrassed by dreams of the most frightful sort, such as falling down precipices, suffering shipwreck, being devoured by wild beasts, are common enough on these unhappy occasions. Some histories of the effects of vapours, are as old as the days of Galen. Arc noct-ambuli of the nervous temperament ? Another train of tormenting symptoms, are those head-aches which accompany ner- vous disorders'. Some times only one side of the head is affected, and the pain receives the name of hemicrania: when it is in the fore- head, and gives the sensation of a nail being driven into tht bone, it has been called clavua hystericus, as being peculiar to the hysterical. But this last kind of pain is not more peculiar 191 to women than the globus ; males are also sub- ject to it. A nervous head-ache in the occi- put, is often attended with a sense of coldness ; as if very cold water, or a current of cold air, was poured upon the part. Vertigo, to such a degree as to make the patient fall down, dim- ness of sight, tinnitus aurium, partial or total deafness are associated with these complaints. These head-aches frequently seize persons at regular intervals, and have obtained the name of periodical head-aches. Accessions and in- termissions of pain that acquire regular move- ments, must depend on some important law of the system ; and here they are probably direc- ted by the digestive process. To this class of symptoms may also be re- ferred that singular and obstinate pain of the face, called dolor facet, or tic doloreux, by the French. Tt is said to have been once cured by Dr. Haighton, of London, by dividing a branch of the fifth pair of nerves, which was supposed to be the seat of the pain. But me- dicine must become a bloody art indeed, if the organs of sense and motion are to become sub- jects of surgical operations. Flatulence, con- stipation and nervous feelings, are known to 192 be attendants of this pain: it affects chiefly women, and those above thirty ; but it is not confined to a particular spot of the face. It is doubtful to me, whether this tormenting af- fection is ever met with but in the nervous constitution ; at least in such only has it come under my observation. I cannot therefore see any reason for considering it a distinct disease; for it has always been relieved by the general method of cure, though it is apt to return. Pains, cramps, and contractions of the joints and muscular parts, are not uncommon symptoms : but the most painful are those of the calves of the legs and soles of the feet. I have a patient now, a man of large size, who is drawn to the one side, and the muscles of the abdomen contracted into irregular lumps. This man is strongly affected with hypochon- driackism ; is jealous of his safety, and asks my servants if they ever hear their master speak of him.* He inherits the temperament from his mother. * This poor fellow,' who lives 30 miles from New- castle, lately asked me by letter, whether I thought he ought to go into a lunatick hospital, as he considered himself insane. 193 Persons subject to these diseases are Very liable, in advanced life, to hemorrhoidal tu- mours, andprocedentia recti; which at times are most afflicting symptoms, as they prevent all kinds of motion or exercise. These are too often the unfortunate consequences of frequent purgatives, especially of the mer- curial and aloetick kind ; which tend most to weaken the bowels and bring on a constant tenesmus. It is the nature of these diseases to invert the regular economy of both body and mind. We therefore frequently hear patients express sensations, as if they had no bowels, and all was vacuum within them. So sensible are they at times to arterial pulsation, that they say they have pulses all over ; and count the strokes of the heart without applying the fin- gers to any artery. When dyspnoea, with cough and hoarse- ness, is present, it is of considerable impor- tance to distinguish how far these form a part of nervous indisposition, for phthisis frequent- ly supervenes without much cause of suspi- cion. When irregularity of the period accom- ] panies these pectoral symptoms, they become R 194 still more equivocal. Even the expectorated matter only helps to create doubts. But there is a kind of cough, that has not inaptly been called nervous cough, which consists of a short hick, something approaching to a hoop, and >not attended with much fixed pain of the breast : nor does the difficulty of breathing which accompanies the nervous cough, give the sensation of so much fulness of the chest, or oppression ; but rather a feeling that the cells of the lungs refuse to admit the air. The nervous cough is also more affected by the passions than that of phthisickal persons. The family predisposition will enable the physician. to form a correct prognosis on most of these. occasions. I have seen some obstinate hiccups, in both flexes, in these diseases, that resisted every thing that could be thought of; nor did they intermit, for some weeks, except during sleep. Hydrophobia has been met with in these diseases, and where the dread of swallowing liquids was little short of what has been ob- served in canine madness, I believe in all situations where deglutition is difficult, when cot owing to mec.hanickal compression, it is 19o found more painful to swallow liquids than solids. The hydrophobia of Rabies, is to be considered as a nervous symptom, expressive of the inverted action of the osophagus and muscles of the pharynx. The dread of water is therefore to be explained, from the im- pression which the mind receives on looking at the water, as associated with the act of swallowing it under the reversed motion of the muscular fibres which perform deglutition.. It must be nearly allied to the globus hysteri* cus. It is strange that anatomists should look to the pharynx and gullet, for the seat of hy- drophobia ; which must be imputed to the sensorium commune, and is not to be detected by dissection. I have, however, frequently known the throat so contracted, and the tongue so cumbersome in the mouth, that nothing tut slops was taken down for months, under nervous indisposition. The state of the pulse in these disorders, is as variable and inconstant as all the other- sensations of the patient. It is sometimes regular and equal, in conditions of great pain and suffering: and at other times, is found uncommonly qukk, unequal, irregular and 196 intermitting, when the symptoms are very moderate. It may be presumed, from these affections being primarily seated in the ner- vous system, they only affect the vital functions at intervals. I have certainly known the pulse remain with little variation from health, in some fatal cases, till within a few hours of dis- solution. Yet nervous persons in general, have a quick pulse ; and in some instances it has been noticed at 200 in a minute. Their senses being all uncommonly acute, a sudden noise or start, quickens the pulse, and pro- duces palpitation in an instant. But the most formidable aspect which these diseases assume, is when they have lasted so long, as to bring on fatuity, or imbecility of mind, melancholy and madness. Among drunkards in particular, these kinds of termi- nation are very common; and we impute them to the disorganization of the brain it- self.* For in these cases, whatever causes an increased determination of the blood to the • See the account of the dissection of cnebriates, where the cerebrum was found diseased. Essay on Drunkenness, 2d Edition. 197 head, increases the delirium; this is observed particularly with regard to ardent spirit and opium. But nervous people commonly die of apoplexy, palsy, atrophy, dropsy or con- vulsions. I have forborne to mention many of those idle stories, which some authors take delight in telling, as the effect of extravagant illusions of fancy, which nervous people are said to be subject to. I hold their whole complaints to have a real existence : and from whatever Cause pain may arise, it is the province of the physician to employ his art to subdue it; not to ruffle an irritable mind by unseasonable lev- ity, or expose a morbid sensibility to insult and reproach. Dissections have not forwarded our know- ledge of these diseases : and indeed when we consider the nature of their symptoms, symp- toms flying from one organ to another in an instant, and thought succeeding thought with the rapidity of lightning, we are the more in- clined to think that inspection of dead bodies will not improve our method of cure. It i3 true, that the stomach, liver, pyrolus, intes- tines, mesentery, kidneys and bladder, and R2 198 the uterine orguus in females, have at times been found diseased: but such deviations from the healthy state, must:n general be secondary symptoms, the effect not the cause of these ailments. In the transitory jaundice of dys- pepticks ; or in the migrating cramps, globus, or strangury of the hysterick affection, what physician would look to organick lesions for their seat ? Persons are known to die of the most dreadful symptoms of these disorders, where nothing could be discovered by the knife :* which with all other circumstances attending them, confirm the belief, that their pathology is to be sought for in the nervous system; which will be our next.task to investi- gate. • Whytt on nervous diseases. 199 CHAPTER VI. The general doctrine of these diseases, THE most prominent parts of the charac- ter of these diseases are, that they occur chiefly under peculiar modes of living; are hereditary, and affect, in a particular manner, the organs subservient to the preparation of nourishment. It appears from what has been said in the preceding chapters of this work, that they are unknown in the savage state ; but rarely met with among rusticks ; and are to be found in abundance in large towns, or wherever luxu- rious habits have displaced simplicity of liv» ing. They are so far to be classed among mental disorders, that a disposition of mind, not easily to be defined, attends every degree and stage of them ; beginning with uncom- mon sensibility to all impressions ; peevish- ness of temper; irresolution of conduct; sudden^ transitions from sadness to joy, and 200 the contrary ; silent or loquacious ; officiou3ly busy, or extremely indolent; irrascible ; false perceptions ; wavering judgment; melancho- ly ; madness: exhibiting in the whole, signs of deranged sensation. These diseases receive a stronger tincture from the manners of the age, than any others to which the human frame is li'abte : and when they appear in great numbers, as in the pre- sent day, they form an epoch in the physickal and moral history of society; so wide is their range, so important their influence on the state and condition of mankind. I have seldom known any of those persons denominated Quakers, to have been severely troubled with1 nervous complaints. This testimony is at least honourable to these people ; and some proof of the good moral conduct and sobriety which prevail among them* The causes which produce nervous disea- ses, may be divided into two kinds, namely, those which arise from the mind ; and those which arise from the body. Of the first kind, are all the disorders of the passions : of the second kind, all those causes which affect par- ticular organs of the body, that by their office, 120 are intimately connected with the nervous system. Many of these causes, of both the mental and corporeal class, act for a length of time before they bring forth actual disease ; but this mode of operation would seem to hap- pen only where there was no predisposition.— They may therefore be said first to create pre- disposition, and when this is sufficiently done, a train of symptoms appears which constitutes real disease. To predisposition, whether hereditary or acquired, I give the name of nervous tempera- ment, which is now to be considered as a per- manent state of body, that cannot be easily changed, and will commonly remain for life. This temperament is to be observed in diffe- rent shades and gradations, mixed with the other temperaments ; but where it is exqui- sitely formed, it is know by the following signs : a sensible, irritable, and mobile condi- tion of nerves ; by which different organs of the body, from slight causes, are urged into vio- lent and involuntary action; and their motions and sympathy often reversed; giving birth to false perceptions and erroneous judgment; and sometimes accompanied with pain oftheaccutest 203 kind. This temperament is said to bear ail evacuations ill, especially the loss of blood ; and also is easily injured by medicines of the rougher class ; it is not very liable to diseases of the inflammatory kind.* It is evident, from the history of these dis- eases, that where the nervous temperament prevails, all the causes which operate upon it,. bring forth motions and sensations very diffe- rent from what is found in a healthful struc- ture of nerves, in persons Who are without the predisposition. This is more exemplified in What may be called the mental causes, than in the corporeal.- The moral evils of life are ve- ry much of a relative nature ; their effects de- pend, in a great measure, on our capacity of feeling, for receiving them ; or the fortitude which we are able to oppose to them. Thus, one man is condemned for sinking under ad- versity, as a proof of deficient virtue and spi- rit ; while another is extolled for his courage, as a token that he possesses nobleness of mind. Yet the physickal trait of their tempe- raments, will best decide with impartiality op *Gregorii med. ther. conspect. vol. iL chap. xxhi. 203 their respective merits. The first may be a weak nerved being, and a good man ; and the other, under apparent resolution of soul, may possess nothing beyond want of feeling. But this even applies to the corporeal cau- ses. Let the two persons start together, to drink a bottle of ardent spirit in the twenty- four hours, for life. The nervous man will, most likely, .find his frame shook to pieces at the end of two weeks, or as mapy months y—■ while the other will continue his potation for as many years. When the first dies, of weak ,nerves and tuberculous liver, at the end of three months, the other may still remaia strong and hale. It may now be said that the first was a drunkard, and died felo do se: but the survivour will have a chance of preserving his reputation for sobriety. Of so much im- portance is the study of temperament in judg- ing of the causes of these diseases- The living body possesses the faculty, if I mav so call it, of receiving impressions, and retaining them, even to the hazard of its de- struction. All predispositions are of this kind. When a person subject to gout, undergoes a long mercurial course for the cure of syphi- 204 lis, he may not be always warned of the in- crease of predisposition, which he will infalli- bly acquire by this process : though he may be duly told of the necessity for mercury to sub- due the other disease. And if it were left to his choice, he would still prefer the antisyphi- litick regimen, and make the best he could of his gouty diathesis. If besides, he is attach- ed to the bottle, or has contracted the habit of taking opium jn large doses to ease his griping pains, he is going fast on to give the final blow to health ; and the last degree of this, is the completion of predisposition, or constant gout and nervous affliction. So that predisposition, in its various stages, is the medium between health and disease. A gentleman subject to gout, weak nerves, and all their horrours, con- sulted me some time ago. He look his wine freely, and an opiate eveij ni^ht at bed-time. The last, he said, w~s to ease his spasms, and to give him rest. He was also of extremely slow bowels. I warned him of the dangerous habit he had got into ; and in order to save the remainder of his constitution, recom- mended him to give up his bottle and his lau- danum immediately. But the conflict was too 205 great for his fortitude ; he did not call upon me a second time. This man, I dare say, was both able and willing to pay a physician, pro- vided he could find one to his mind. That society must be undergoing the last degree of vitiation, where the faculty of medicine re- ceives gold, and returns poison. All those passions of the mind, which have been narrated among the causes, act imme- diately on the nervous system; whence a train of sympathetick affections instantly com- mence throughout the whole body, but espe- cially in the chylopoeietick organs. And again, those causes which induce nervous dis- orders through the body, affect first the diges- tive and assimilating powers ; and are from them reflected on the nervous system, whence commences a train of inverted sympathies and false perceptions, which show how far the mental part of us is concerned in this general tumult of sensation and motion. Why a station so exalted in the animal eco- nomy was given to the chylopoeietick viscera, we can only account for from the pre-eminence they occupy in preparing the nourishment of the whole system. The appetite for food, the s 206 digestion of it, chylification, sanguification, and the nutriment derived therefrom, are a- mong the most wonderful operations of nature. One of the first instincts of our existence is the desire for food. Nay it is probably the firs*, and coeval with the rudiments of the foetus. Some peculiar inherent power, not to be expres- sed by abstract terms, enables the vivified germ to draw nourishment from its nidus, the fluid which surrounds it. Every particle of the nu- tritive juices, elaborated by the maternal pro- cess, is attracted by the congenial sympathies of the embryo. These juices hold in solution what is to be the future solid, such as cellular mem- brane, muscle, tendon, bone, and nerve itself. The nervous system, or sensorium, must be the basis and the prime director of this crea- tive process, till the human form in all its parts is fully evolved. The circulation of the blood, from the mother to the foetus, now commen- ces, and continues the supply, though not by a direct continuity of vessels. And the placen- ta, by oxygenizing the fcetal blood, supplies the the place of the future lungs. When the re- quired bulk is completed, the infant, endued with peculiar instinct, urges the womb to ex- aor pel it, which terminates in the birth. The nourishment which the child received from its mother before birth, is now to be prepared in part by its own organs. I say in part, be- cause milk is a substance half animalized, and nearly ready for assimilation. We thus comprehend three stages in ani- mal existence, where the manner of receiving nourishment is varied. The first stage is li- mited to that early condition of the germ, be- fore the circulation of red blood can be distin- guished. The second stage commences with the circulation of red blood, and terminates with the birth. The third stage begins with the birth, when the nourishment of the body is to be prepared by the chylopoeietick viscera, which continues through life. The human stomach is an organ endued by nature, with the most complex properties of any in the body ; and forming a centre of sym- pathy between our corporeal and mental parts, of more exquisite qualifications than even the brain itself. Yet the knife and eye of the ana- tomist do not discover the whole important station it holds in the economy : we must look to the living sytem for thoie nice connections 208 of cause and effect, and that source of asso- ciation, which give it a relationship to so many organs, both in the healthy and diseased state. There are few diseases in which it does not participate : even slight blows upon it have proved fatal ; but its wounds are to a certain- ly mortal. In all those disorders whose seat is the nervous system, it particularly suffers. In fevers of every description the stomach is peculiarly affected ; and till the febrile move- ments decline, the functions of this viscus arc suspended. An organ intended for such important pur- poses in the animal economy, must receive from the hand of Nature singular tokens of her favour. Hence we find ail those viscera, which assist in preparing the chyle, and what is called the assimilation of the food, joined in a circle of nervous communication, of which the stomach is the centre. One portion of nerve is distributed over the whole ; so that while they are all employed in one purpose, disorder cannot take place in any one of them, without the whole being thrown into confu- sion. Anatomists have discovered an unusual 209 share of nerves about the upper orifice of the stomach ; from which it was thought by some philosophers to be the seat of the souL These nerves of the stomach are derived from the par vagum, or eighth pair, which communicates with the great intercostal or sympathetick ; and by it, is connected with al- most every other nerve of the body. The semilunar ganglion of the great sympathetick, supplies particularly the liver; %ftll bladder and ducts; duodenum; pancreas; spleen; jejunum ; ileum ; and part of the colon, &c.» the renal glands, kidneys, ureters, and blad- der ; the womb, ovaria, testes, &c. are all supplied by the same nerve; and joined by others from the lumbar vertebra?. The mus- cles of the pharynx, and trachea, those of the neck and.lower extremities, are even connect- ed by branches of this nerve. The lungs, heart, and diaphragm, being all furnished with nerves, which communicate with the great sympathetick, it would appear, that this nerve is the grand link or chain, which con- nects the vital, animal, and natural functions with one another. When the great sympathetick enjoys its s2 210 full health, all the organs to which it is distri- buted will be found performing their different offices with vigour, accompanied with plea- surable sensation. When the stomach has been replenished by a full meal, after tome time, sleep supervenes, which is easy and sound ; and with this commences the process of digestion; the solution and expulsion of the food from the stomach ; its mixture after- wards with bile, pancreatick juice, and intes- tinal mucus. Every pore, vessel, duct, or gland, that is engaged in that great business, contributes a share of soothing influence to the dormant animal functions ; and the tempe- rate man awakes refreshed and invigorated in body, with faculties equally clear and reno- vated. But the dyspeptick stomach exhibits a very different train of phenomena. After the repast, sleep scarcely closes the eye-lids of the nervous man ; a croud of unpleasing ideas disturbs the mind; flatulence, acidity and bor- borrigmi, torment the body ; digestion goes on imperfectly ; and he wakes low, languid, and unrecruited; sick at stomach, and with- out appetite for breakfast. The pathology of these diseases is there- fore to be chiefly sought in the functions of 211 this nervous communication ; and most of the symptoms to be referred to the same. Thus in a dyspeptick condition of stomach, such as attends nervous complaints, it is not the mus- cular fibre alone of that organ that is to be considered as diseased ; but every gland and pore, exhalent or follicle, that separates either gastrick juice or mucus ; and consequently all the fluids are poured forth in a vitiated state. The appetite will then be irregular, some- times suppressed, sometimes voracious ; the acidity will increase so as to become painful; the food will remain undigested, and uneasi- ness, and inflation of stomach will succeed. Other viscera will, by consent of nerves, be also deranged in their respective offices. The pancreas, its juice and duct are affected. The liver will secrete the bile in quantity and qua- lity, both different from its healthy state ; and the ducts will be irregular in conveying it forward. The peristaltick motion of the in- testines will be inverted and inconstant; and constipation or diarrhoea be the consequence. Even the kidneys, more remotely connected, will discover indisposition, by the urine being voided turbid or pale, in spare or profuse quantity; sometimes with pain in the loins, ureters, bladder, testes, or mammae. Those uneasy sensations which rise to the throat, and there give the idea of strangulation, often at- tend the stomach affection. The lungs expand with difficulty, the breast labours, the heart palpitates, the eyes grow dim, a giddiness comes on, confusion of thought and insensibi- lity commence,- and the patient often falls down convulsed.* There is not a muscle or organ of the body that receives a single ten- dril of this sympathetick nerve, without par- taking more or less, in these diseased feelings* But there are not two people who feel ex- actly alike, in a disordered condition of sto- mach ; and this difference depends on causes so various, that the idiosyncrasy, or peculiarity of constitution, in every individual, must be sought for before it can be explained. Early habits, pursuits in life, modes of living, mo- ral character, preceding diseases, amusements, professions, seasons, climate, &c. must all be taken into the account. Thus one person suffers by severe and obstinate head-aches ; * Hystericus, and epilepsy, cr falling sickness. 213 another is prone to hysterick or epileptick fits ; some are afflicted with cramps and spasms of stomach, others by acidity and flatulence. The liver and biliary ducts, with deficient secretion of bile, its increased quantity, or obstruction from spasm, mucus or gall-stones, and suffusion of the skin, are peculiar to one constitution : while bowel complaints, nephri- tick pains, urinary calculi, and strangury, ha- rass another. Nervous females particularly suffer at the period; in all irregularities of it, from whatever cause ; and in the puerperat state. Some persons sink more under dejec- tion of spirits ; while others exhibit sudden vicissitudes from high to low, and the con- trary. Temporary insanity is more frequent with women than men ; and it attends some of them during every pregnancy. Yet I hold all these, and many other shades of nervous indisposition, to be still one and the same dis- ease. Nay, we frequently observe the family peculiarity to be hereditary; and often dis- tinguished by external signs, as the child hap- pens to be like the father or mother. The nervous power, in some persons, is precipitate in its movements, tumultuous and convulsive, 214' and gives a hurry to all their actions. Other* again appear more sluggish and deliberate, where the nervous power is more torpid ; but it is at the same time liable to inconstancy when under the influence of different pas- sions. We know so little of the nature of the ner- vous power, that we can only judge of the moral causes of nervous indisposition, from their effects. Some of the passions have re- ceived the name of exciting, and others that $f depressing; but their effects on the nervous temperament, seem much alike. The chief of the passions, such as anger, joy, grief, fear, ho. destroy appetite, disturb digestion, pre- vent sleep, make the breast labour, and the heart palpitate ; render the mind fickle, timid, incapable of judging accurately, &c. Here is no proof that any of these passions weaken the nervous system; they only dissever that combination, or association of ideas, which impresses the mind with pleasing objects ; and which dissevermcnt to the mind is painful, and throws all the more sensible organs of the body into immediate disorder. The mind and body being connected by the nervous sys- •215 iem, the same train of symptoms appear, when ■those causes are applied to the body, which -first affect the chylopoeietick viscera ; such as a mercurial course, or a debauch with ardent spirit or opium. Now, what can be the reason, that these passions, or the articles just men- tioned, have such extraordinary action on ner- vous people, while on others they have no such effect? I would explaiu the fact in this man- ner : the hereditary temperament is supposed to inherit all the bad impressions of its pro- genitor, hoarded as it were in the structure of its nerves : in like manner the acquired tem- perament retains, or records as it may be termed, all the effects of vicious indulgence. So that when any fresh gust of passion arises, or any luxurious stimulus is applied to any portion of the sympathetick nerve, these ac- cumulate the quantum of predisposition ; and a nervous fit, or a bilious attack, is the imme- diate consequence of every new trouble of mind, and of every recent debauch of the bo- dy. Thus the habit may become so complete- ly nervous, or in other words, the predisposi- tion may arrive at that height, that the facul- ties of the soul will be worn out, and fatuity 226 take place; and the body will be so enervated as to be in a state of constant pain, tremour or convulsion. Such cases, in no small numbers, are certainly to be seen every day, by medical observers who possess discernment to appre- ciate experience. The operation of ardent spirit, which in- cludes wine and all fermented liquors, and opium, if not all narcoticks whatever, is much alike on the animal economy. They assail in the first place, the nervous system, and all other effects are secondary. The nerves of the stomach feel the first injury : but so inti- mately are these nerves connected with the whole that supply the chylopoeietick viscera, that they are instantly drawn into consent. The stomach, intestines, pancreas, liver and ducts, become thickened, and grow-torpid by long indulgence in these articles, and unequal to their functions. But it will not be doubted by any person who has attentively watched the effects of opium and ardent spirit, that all the early symptoms of indisposition which they create, are purely nervous, and extended bv sympathy. I was formerly of opinion, that the enlarged liver v/as owing to the constring- 217 ing power of the alkohol being spread from the duodenum to that viscus through the ducts. But this explanation is not satisfactory : and opium and other narcoticks, cannot act by hardening the fibre or animal solid. The hepatick system must be injured by nervous com- munication and sympathy with the stomach. But if it is common in a severe disease, and after long continuance, for the liver of dvspep- ticks to be found sometimes enlarged, where no vinous stimulus had been used, such a case must have been of nervous origin to a certain- ty ; and from this we have a right to conclude, that the diseased liver of drunkards is almost always of this kind. When the hepatick nerves are rendered weak, mobile, or torpid, by the excessive use of alkohol, it necessarily fol- lows that this debility is extended to the whole substance of the liver. There is no proof that an inflammatory stage and fever, are always the consequence ; on the contrary, I believe inflammation seldom happens. The hepatick system of inebriates does not appear injured till a very considerable degree of debility has taken place throughout the body : there is a general derangement before this assumes any T 218 signal mark of disease ; and many of the worst symptoms are often present, when no- thing beyond nervous affection can be suspect- ed. Jaundice has too frequently been deemed a sign of enlarged liver: but it so happens that the jaundice of nervous people has little connection with the liver.* The irritable, or torpid state of the duodenum and ducts, just as the nervous power happens to be deranged in them at the time, is the most common cause of biliary obstruction, and consequent jaun- dice. Nay, the appearancevof jaundice must often be a proof that the secreting oflice of the liver is perfect. JDuring the inverted mo- tion of the muscular fibres of the intestines., so peculiar to the nervous temperament, the opening of the duct that conveys the bile, from its singular form, must be very liable to obstruction. And this is thought to be the most common cause of icterus. * Within these four years, of rich and poor who have consulted me, not less than 50 cases of supposed diseased liver, were of the number. Yet the treatment proved that no fixed hepatick affection was present. Many of these had their complaints aggravated by the previous -use of mercury. 219 But if the torpid and enlarged liver is thur proved to arise from nervous debility, must not the cure turn upon an invigorating plan I The first step to this must be to remove the causes which brought it on ; in the drunkard, let the bottle be laid aside entirely; let such mental and corporeal stimuli be used as have a restorative quality ; and health must return^ if it can be brought about by human means. But these principles apply with still more force where biliary obstructions infest the fe- male constitution. The irritable nervous sys- tem, and delicate bowels of most women, ought to make medical people consider well before they attempt violent remedies, to over- come obstruction. The true method of cure in weakened females, must be to strengthen the whole chylopoeietic viscera, by such medi- cines as communicate permanent energy to the nervous system : to obviate slow bowels or diarrhoea, to correct acidity and flatulence ; to attend to the quality and quantity of the food ; to regulate the passions ; to observe strict rules of air and exercise ; to avoid cau- tiously every excess in stimulation, whether mental or corporeal: in short, to reverse all 220 established habits, and to force a new train of actions upon the temperament. I speak from much experience on this subject: and it is ad- mitted by the advocates for the mercurial course, that they have no certainty of the sup- posed liver affection being removed ; but their patients are at intervals returning to the medi- cine ; and we have known some instances where ladies of the nervous temperament were taken very unexpectedly out of their hands, by what was called the cramp of the stomach ; a symptom that sometimes follows with a quick pace the exhibition of mercury. These gen- tlemen must have often met with obstruction and suppression of urine among nervous pa- tients ; yet it does not appear that they consi- der calomel the best relief to the kidneys and bladder. In fact, in most cases, of both jaun- di«e and ischuria, we are to look to nervous sympathy for their cause ; for they commence and disappear in general so suddenly, that local causes can scarcely be suspected. We might as well dissect the top of the osophagus for the cause of globus hysterickus, as attempt to fix the pathology of these versatile move aunts in the secreting or other organs ; or 221 inspect the brain of a hypochondriack for the picture of his blue devils. The migratory pow- er which these affections possess, of travers- ing every part of the body, is the inscruta- ble idiosyncracy of the Nervous Tempera- ment. A physician of our acquaintance, for many years was subject to dyspepsia, and conceived that he had a diseased liver, as he termed it. For twenty years he took calomel in large doses very frequently ; and all this time with a manifest increase of his complaint. The bowels however came to that torpid state, as to resist every common laxative ; and he at last got to the enormous quantity of thirty grains of calomel for a dose. I speak fromr his own authority. He became weak and emaciated, and at times suffered great pain ; and sunk under the debility, which was to a certainty produced by the mercurial poison ; for when the body was opened no liver disease appeared ! About eight months ago a medical gentle-- man consulted me for various nervous and dyspeptick complaints. He said his liver was affected; and he had taken calomel, at in- T2 222 tervals, by the advice of a neighbouring phy- sician, for the last twelve years. He had a slight bilious look, and evidently possessed hereditary predisposition ; was rather thin and the bowels in a very irregular state. I recom- mended the usual strengthening plan, with horse exercise, and abstinence from vinous liquors, and opium, which he used freely. In a few weeks he got well, and recovered his flesh. In four months he felt some return of his indisposition, and resorted again to his calomel. 3ut his bowels became more un- easy, and he felt a constant tenesmus. He came again to me, and he suspected when I saw him, an incipient ascites ; nothing how- ever appeared outwardly. I repeated my for- mer cautions to him about the use of mercury, for I looked upon it as the chief cause of his sufferings. He took the advice of two emi- nent physicians, at some distance from his home; and they prescribed mercury. He began the plan recommended, and died in a few weeks; in my opinion, with a constitu- tion destroyed by this medicine. The mistaken pathology of these diseases, it thus appeais, had given birth to this un- 223 warrantable use of mercury. Such cases can- not be made too publick, in order to caution inconsiderate people against the indiscriminate administration of medicine, so capable of doing harm : the bowels of these gentlemen were evidently reduced by it to a state of palsy. But however afflicting the condition to which the body is often brought by nervous infirmity, the mental indisposition is the cause of greater misery. To enumerate all the de- grees of deranged intellect in these diseases, would be a difficult and useless task. They comprehend all that is extravagant in delusion, or absurd in fiction. The acute, but too of- ten false perceptions of nervous people, are an apology for some of the stories we hear of ap- paritions, of magick and of witchcraft, that have at different times imposed on the credul- ity of mankind. Their deluded and vivid imaginations are capable of believing any thing : and instances of supposed supernatural agency, conceived in a dream, have often made such strong impressions on the mind, as to be attended by consequences of great im- portance, not only to the individual, but to 224 the community. All jugglers and mounte- banks find these persons an easy prey. The imposter Mesmer, who, about twenty-three years ago, exhibited his talents in ani mal mag- netism, by exercising nervous people at a kind of ordeal which he had invented, found them answer all the purposes of his deceptions ;< and many well informed men believed firmly in the truth of his doctrines. Yet the effects which were produced, were plainly owing to sympathy, and the power of imagination;. just as we observe one nervous lady fall into a hysterick by looking at another in a fit; or like the two children mentioned before.* The temper of mind with nervous people, renders them very prone to what is called re- verie. In the sunshine of their sensations, much of the rime passes in contemplating ima- ginary pleasures; or what in common lan- guage is called, building castles in the air* And when they are roused from this fool's pa- radise, they are very apt to fall into the other extreme of low spirits and apprehensions. So * See the report of the Examiners appointed by the Ring of Eranee. 225 certainly does a corresponding train of thought follow every odd feeling, in these whimsical disorders. In the introductory part of thrslnquiry, we have given a cursory view of the savage state, so as to shew how favourable it is to vigour and health of body. We there observe man to pass through existence, with wants so few, that he overcomes them by his individual ex- ertions. The spot that gave him birth bounds his travels ; and his knowledge is confined to the customs of his own tribe; so that if he ha3 little call for bodily labour, he has still less for mental acquirements. His diseases are on- ly the infirmities and decay of nature ; but of the whole catalogue of ills which infest mortal life, he is least in danger of being afflicted with those of the nervous class. But how different is man in the civilized world ! He is obliged to undergo a kind of training how to live ; to instruct him in what he owes to himself, and what to society. Where the savage feels one want, the civilized being has a thousand. Devoted either to love or ambition, these impress all his actions with extraordinary vehemence, perseverance, and 226 enterprize. He is no sooner brought into the world, Than he is taught to admire every thing that dazzles, glitters, or makes a no'i3e. His very employment is play ; and all his toys are either shining or sonorous. Flattery is the first expression addressed to dawning intelli- gence : he is called pretty to make him a cox- comb ; named good till he becomes a hypo- crite ; and learns to act the tyrant by seeing every person afraid to disoblige him. Every thing within his view is calculated to prompt his desires and provoke his passions ; no anti- dote is opposed to suppress the one or to mo- rate the other : and he finds example every Where at variance with precept. If he is born the son of a rich man, he is still more unfortu- nate ; as he will be caressed by more syco- phants, and exposed to greater temptations : and to be born a prince, is to be the most unfortunate of mankind. The more complicated and various the pleasures and business, which man is to pur- sue in life, he will be the more liable to defeat and disappointment ; and the more ardent his passions, they will the sooner terminate in ex-- haustion and disgust. The busy scene, there*- 527 fore, leads quickest to satiety : the retired cir- cle preserves the longest enjoyment. So tha* thousands of human beings walk the round of gaiety and dissipation, for the certain reward of nervous debility. It is only at a particular stage of refinement, that these diseases receive their birth : and when they exceed the sum of other disorders in a nation, they afford sure tokens, that that people is passing fast into do- tage, and even under apparent prosperity ver- ging to decline. They multiply in prodigious proportion : for besides the hereditary predis- position whfch taints the offspring, they ar« daily gaining ground from acquired infirmi- ties. When we thus contemplate with a phy- losophick eye, the rise and progress of a na- tion, we observe a kind of phjsickal necessity for the regeneration of mankind. A people, polished and improved to the utmost, cannot •remain long stationary ; it must degenerate in body and mind. It must fall into slavery un- der some powerful invader; or sink by some convulsion of nature ; and with all the arts and elegancies of life, return to the barbarism of its aborigines. Such a change of condition brings man back to pastoral and agricultural 228 habits ; with which' his sinews will be newly strung, and his vigour of body renovated. And with these acquisitions of corporeal re- production, the faculties of mind in a latent state, will accumulate those powers and excel- lencies, that in a future period will exalt hu- man nature to civilized perfection, though still to be exposed in its turn to a similar decline. Although much stress has been laid on the imperfect state of the digestive and assimila- ting powers in these diseases, yet we often find a considerable degree of obesity present, wher« the symptoms of indigestion prevail. But obesity is seldom a proof of strength ; perhaps it oftener accompanies weakness. And the indolent inactive life so often led by nervous people, must favour the deposition of fat. A spare thin habit, is however a more frequent attendant on dyspeptick constitu- tions. The food may not only be badly pre- pared in the stomach, or vitiated by imperfect bile and pancreatick juice ; the lacteals and mesenterick glands must also be diseased, sometimes impermiable, and perhaps ulcera- ted. The quick evolution of acidity, in some of these cases, is surprising ; it is no sooner 229 corrected by alkalies or carbonate of lime, than fresh quantities are felt. There is even reason to believe that some of the intestinal secretions are so depraved at times, as to be- come acid immediately, the accumulation is so rapid. The simple deficiency of bile can- not account for this, unless the bile also loses its alkaline properties, which I rather suspect it does in part. Acidity is not always accompanied with flatulence. The last symptom is peculiar to some constitutions ; and it is most troublesome where sedentary habits are carried to excess, as in some females. The uncommon quantity of air extricated in the process of digestion sometimes, would make us suspect a large proportion of the food or water to undergo chemical decomposition. Some active exer- cise, or quick agitation of the body, affords the most certain relief. The frequent micturition, and strangury, which attend nervous indiges- tion, prevail most when the stomach is loaded with acidity, and this points out the method of cure. I have not made any experiments on the urine in these cases ; but it is likely that the urick acid must, appear in large proportion at that time. u 230 All derangements of the uterine system exemplify in the most striking manner the strong sympathy between the chylopoeietick viscera and these organs. This is observed particularly at the age of puberty ; at the peri- od ; at the beginning of pregnancy;* in the puerperal state; in suckling the infant too long; * Many of my contemporaries at Edinburgh \\\\\ recollect a case mentioned by Dr. Cullen, in his lec- tures on the practice of physick, that strongly proves the power of association during gestation. A lady in a hopeful way, found it necessary to have her robe made easier, and sent for her mantau-maker. But in standing up to be measured, she grew so sick, that it was accomplished with great difficulty. The gown was brought home ; and in attempting to try it on, the lady became so squeamish, that the mantau-maker was obliged to desist, and leave her work to another time. A few days afterwards, another attempt was made to try it on ; but now the very sight of the gown brought on sickness. It was determined to take the gown away, and to hang it up in a dark closet, not to be seen. Even this prtcaution did not avail; the lady could not look at the closet, or pass near it, without feeling immediate bickness. It was therefore carried out of the house : aad this extraordinary association remained till tie lady got her bed. 251 at the change of life ; in all conditions that af- fect the passions ; and more or less in every complaint to which the female may be exposed. It must therefore be of great importance in practice, that the physician should inform himself well, with respect to predisposition and temperament. We thus see on what irra- tional grounds the use of a class of medicines called emenagogues, was founded ; and how necessary it must be in uterine obstructions, to attend to the influence of that chain of sym- pathies on which they chiefly depend. How far the class of nervous diseases is connected with gout, may, perhaps, require much future experience to determine. But as far as the inflammatory symptoms are not con- cerned, the two affections appear to be the same. They both depend on hereditary or acquired predisposition : the causes which pro- duce them are entirely alike : these are chiefly luxurious habits and the debilitating pleasures : all the dyspeptick ailments of the nervous frame, appear in the arthritick constitution. Every derangement of the biliary secretions, partakes in each, of a similar disposition ; the state of the intestinal canal is subject to the 232 like capricious vicissitudes in both; and also the urinary organs. The irritable feelings, and hallucinations of mind, with which both subjects are affected, have an exact resem- blance. And we observe, that the prevention and treatment of nervous indisposition and gout, are to be conducted on the same prin- ciples. No fact in medicine appears more clear* than that the female of every gouty family, inherits in a high degree, the nervous tempe- rament ; and is liable from the general causes mentioned before, to suffer all the infirmities to which that temperament paves the way. This is exemplified by the exhibition of mer- cury and antimony; in the use of narcoticks, particularly tea, opium, and vinous spirit ; in every improper indulgence in food or drink, and in the government of the passions. Gouty constitutions are known to be parti- cularly liable to urinary calculi. The urick acid, which has been found to form so large a portion of these concretions, is most likely evolved during the depraved digestion and assimilation of the nourishment; and after- wards separated by the kidneys, and lodged 233 there, or in the bladder. It would be worth while to make experiments on the morbid acidity of a dyspeptick stomach, for there is great reason to think that it does not differ essentially from the urick acid. All the alka-% lies are given v Lh advantage in these kinds of urinary calculi ; and it is fair to allow their chief effect to be in correcting the acid in the first passages. From what has been said, I shall hope to be justified in not attempting to divide these diseases into genera and species, which have little foundation in nature, and are of no utility in a practical view. Combined in the defini- tion of Nervous Temperament, they bear a near analogy and connection to one another. We thus observe, the person who in youth, possesses a mobile condition of nervous sys- tem, with a temper of mind depending on that, making him fickle, volatile, passionate, will in the advance of life, be les3 irritable ; but will still preserve so many traits of original charac- ter of habit, as still to justify the term. The dyspeptick infirmities will also undergo modi- fication, in proportion to the manner of living and moral habits. Hence melancholy and u2 234 hypochondriackism seldom appear before the meridian, but more commonly not till later in life. On the whole then, it is fair to conclude, that the pathology of these diseases is to be sought in the deranged sensations, and invert- ed sympathies of the great sympathetick nerve ; and in the irregular action of all those organs to which it is distributed, The causes therefore, whether moral or physickal, exert their influence on this portion of the nervous system ; whose office directs the most im- portant operations in the animal economy ; and binds together in one great circle of feel- ing, actions and motions both distant and op- posite. Hence a concourse of symptoms of the most extraordinary kind, that invert the usual functions of so many viscera ; suspend their powers, or give to them new movements ; by which means a train of false perceptions occupies the mind ; and ideas the most mon- strous and incongruous, supplant for a while, all rational thought. In this reciprocal action between body and mind, in whatever part of the circle disease commences, it is quickly communicated to all the others. For as bowel 235 complaints speedily affect the mind and depress the spirits ; so all violent emotions, in their I turn, induce affections of the chylopoeietick viscera, and raise such commotion throughout the sensitive system, as to bestow the nervous character on these diseases. 236 CHAPTER VII. Prevention and treatment. IN giving a title to this chapter, I have been cautious in holding out too much confi- dence in medicine. The word cure, implies a certain and perfect recovery, without danger of the disease returning, a circumstance very doubtful here. But according to what is meant by treatment, I only lay down rules to regulate the practice, so far as experience ha3 approved. This has been the conduct usually observed with my own patients : and as so much depends on their own discretion, it puts them on their guard, and reminds them how far they are to calculate on permanent health. It has been unfortunate for the medical profession, as well as patients themselves, that persons labouring under nervous disorders, have too much expected from the prescription of the physician, and the shop of the apotheca- ry, what is only to be obtained from their own 23? caution and circumspection. We thus find most of them ready, and greedy to swallow every medicine that is recommended ; but stubborn and untractable in all that relates to breaking in upon established habits and cus- toms ; whether of luxurious living, depraved appetites, indolence of body or mind, or vi- cious indulgence of any kind inconsistent with health. Many of these habits, it is true, are so far interwoven with the constitution/as to make some changes almost impracticable : but as indisposition is so frequently brought on, or aggravated, by the improper conduct of the patients themselves, the physician cannot be too much on his guard, in demonstrating to them all that belongs to their own government and demeanor. The medical adviser there- fore, who observes the most disinterestedness towards his friends, will often be the first man to be dismissed ; while the selfish dissembler, however ignorant, will become a favourite, and engross the emolument. On such an oc- casion, the virtuous mind of a liberal physi- cian, will know where to look for approbation. This branch of medical practice has com- monly been reckoned one of the most lucra- 238 tive ; for the subjects of it are generally found among the affluent: they are also seldom without some complaint that requires assist- ance ; and they measure their comforts too often, by the quantity of medicine that is serv- ed up. Nervous people are moreover, en- dued with acute feelings ; liable to act from the first impression and impulse, and easily deceived by the designing and interested. And should they fall into the hands of a gos- siping physician, or a wheedling apothecary, these personages become a kind of appendage to their establishment, if not fixtures in their houses. Being singular in the selection of friends, they seldom mix in company; seden- tary from habit, they go little abroad ; their amusements and recreations are thus limited, and such as possess the talent of bring- ing news, and telling a story, are at all times welcome guests. But as the tale of their own complaints engrosses so much of their conversation, a medical gossip, before all others, is the most acceptable. Neverthe- less, let the nervous and valetudinary beware how they trust their health and their purse in such hands. 239 The prevention of all diseases depends on a knowledge of their remote causes. If in the former part of this inquiry, it has been found necessary to contrast the health of the savage state with that of the civilized con- dition of mankind, for the purpose of tra- cing causes from their origin, it does not fol- low in prescribing regulations to the nervous and infirm, that we are to imitate the robust exercises of the barbarian, for the sake of strengthening the body ; or to yield up the re- finements of education and polished society, in order to subdue sensibility of mind. The lesson is only so far in point, as it tends to confirm general truths by an appeal to facts, or to illustrate a precept by showing an example. In the present diseases, according to the history given, we admit a predisposition of bo- dy, without which, it is probable, they never appear. This predisposition may be either hereditary or acquired; to both we give the name of nervous temperament. What there- fore relates to correcting and preventing pre- disposition, must begin with the earliest sta- ges of infancy, and includes the whole rules of nursing and rearing children. 240 Man is so much the creature of habit and imitation, particularly with what belongs to his food, air, exercise, and cloathing, that he may be moulded into any form we please. Nature has wisely provided milk for the infant, as best adapted to the delicate digestive organs and weak frame of early existence. This kind of food ought to be continued as long as it is ca- pable of giving due support to the body. The mother, if possible, ought to suckle the child till it is nine months old; when cow's milk may be substituted. And it is worthy of re- mark, that the fodder of the cow very much affects the milk, such as grains and turnips, so much in use near great towns. The first article makes the milk disposed to acescency ; and the turnips impregnate it with a disagree- able flavour, which comes from an oil in the tops and rind. Such qualities are hurtful to the stomachs of infants : and grass and hay are the natural food of this useful animal. A child that is to be brought up by the pan and spoon, an it is called, it is obvious, ought to have the milk in the best perfection. This is a practice which I am sorry to observe is sometimes too lightly given into, in faoiilies. 241 I have weighed its merits fully, in rearing my only child^n this way, to fulfil the wishes of an affectionate mother. But, though my dar- ling boy has surmounted his loss with the best possible health, I would not recommend this mode of nursing on any terms, if it can be avoided. Nothing can compensate for the want of the breast to the infant. About the third month, a little pounded biscuit, pre- viously softened with a little boiling water, may be added to give the milk consistence : and from the beginning, as much brown sugar may be mixed, as to give it the sweetness of mother's milk. Sugar, it ought to be remem- bered, is a bad ingredient in the diet of in- fants. The infant may be confined to milk for the first year; when a mess of chicken, veal, or mutton broth, may be given once a day, taking care to add nothing of the aromatick kind. If however the infant is much harrassed with aci- dity, animal broths, such as gravy soups, are not only the best substitutes, but the best me- dicine. After two years, the diet may be ex- tended to a little solid animal food, some kinds of fish and eggs, but still with a large propor- w 242 Cionof milk. All pastry must be carefully shun- ned : sweetmeats of every sort are hurtful : every made dish, into which seasonings and sauces are put, ought to be avoided, as being a chief cause of stomach affections. All beer3, ales, wines, and spirits, are excluded from this anti-dyspeptick regimen. Puddings made of rice, or light bread, may be allowed.; but those of unfermented flour, have all the disad- vantages of pastry. Cheese is gross food for children.: and butter should be sparingly used. Vegetables may be eaten with animal food ; the child being allowed sufficient exercise out of doors, will always find them easy of diges- tion. The object to be kept in view, in re- commending for infancy and childhood, a diet sufficiently nourishing and easy of digestion, but at the same time, mild and bland, is, that the appetite may become accustomed to no high-seasoned or luscious dishes ; or the sto- mach inured to any hot or stimulating article. Were these rules strictly attended to in families su'oject to gout and nervous diseases, many scenes of misery and affliction might be prevented. It is a fact, to be daily observed, that the offsprings of these families, arc, cf all 243 mankind, the most liable to fall into habitual drunkenness, and the love of luxurious feast- ing. Their feelings and sensations are of that acute kind, that they easily receive the im- pression of stimulating articles, and are quick- ly susceptible of the pleasure of taking them down. • Tea and coffee are excluded from this diet, as possessing a narcotick quality : milk is the best breakfast, but those who may incline for more variety, may use cocoa. Cocoa is 3 mild, wholesome, nutritive food, and after a little perseverance very grateful to most peo- ple, and easy of digestion. From what has been just delivered on the diet most proper for infants and children, grown-up persons will see reasons, why they should prefer a similar conduct in the choice of their food. This is indeed a serious evil with most nervous and bilious people : they commonly indulge in high seasoned dishes, and use great quantities of hot sauces or pep- pers, for the purpose, as it is thought, of over? coming the flatulent propensity of their sto- machs. I have before condemned this cus? fom : where flatulence prevails, the stomach 244 should select plain fare, and that in small quantity ; and after a short rest take some ac- tive exercise, which will afford certain relief. The value of air and exercise to health, is amply pointed out in the preceding parts of this work : attention to them ought to begin with early infancy. The child must be exer- cised in the open air, that is ever to attain due srength or stability of frame. The most spa- cious and well ventilated room cannot supply the want of the external atmosphere. A de- gree of vigor and fortitude of mind is insensi- bly acquired by being exposed to the weather ; while listlessness and depression of spirits as constantly follow confinement within doors. Much of this mental exhiliration must be de- rived from the objects which refresh the eyes. The sedentary life falls more to the lot of the girl than the boy ; and is too often encouraged by those preposterous modes of education to which young females are exposed : but cer- tainly a sedentary life may be considered as the chief cause of female ill-health. I have heard a mother boast of her daughter being attended by five masters, in different branches of education, in the day, besides her task ia 245 the boarding school. What human body or mind, at the age of fifteen, is equal to such a trammel of study ? Let the discerning mo- ther therefore, reflect in time, on the magni- tude of the fault, if she bestows her daughter with a sickly constitution as a dower, on her husband. Can any evil in this world be worse than constant bad health ? How melancholy is the state of that family that is daily beset by an attending physicLn and apothecary; continually served with medicine ; and a large proportion of income annually consumed la support of its physical retinue ! Among children descended of nervous and bilious parents, it is a caution worthy of every well informed physician, to be guarded in the use of emeticks, purgatives, opiates, and worm medicines. The last articles require particu- lar animadversion. The fathers and mothers of such families, have too often been in the habit of using medical prescriptions on every slight occasion : and very naturally think a similar practice necessary for the health of their children. Worms can only be consider- ed as the consequence of a weak condition of bowels ; so that their prevention and cure in w 2 246 children, must turn on strengthening the vis- cera, and expelling the vermin. A brisk pur- gative is commonly employed for dislodging worms, and calomel has been the chief ingre- dient. But calomel ought never to be given alone ; it is best to join it with jalap or rhu- barb ; though these articles by themselves are sufficiently powerful. I usually give mag. uff. with the jalap or rhubarb, with a view to the dyspeptick state of the stomach ; and follow this purge with gentle doses of bark, colomba, or any other suitable bitter. Nothing answers better than the sem. santon. or common wormseed. With all these I combine magnes. ust. or cret. prepar, as the bowels happen to be slow or quick. Some chalybeate, such as the red oxide, carbonas ferri, or lematura, may also be advantageously added. When these have been taken for eight or ten days, the brisk purge may be repeated. This plan may be continued for two or three weeks at a time : it will invigourate the digestive powers, and the general habit: and while it enables the bowels to expel the worms, it will prevent their generation by removing the cause. No- thing can be more cruel than forcing the bow- 247 els of children by drastick purgatives to evacu- ate worms ; the most active will sometimes fail in doing this ; whereas the invigourating method is sure and safe, and cures radically. What other precautions are necessary for the health of children, will appear sufficiently plain from what has been said on the causes of these diseases. These causes must be avoi- ded, to insure success. The inhabitants of towns ought if possible, to place their children in the country for the benefit of education. It is not merely the pure air, and space for re- creation and exercise, that a country situation affords, which make it preferable ; other con- siderations of equal weight, are to be taken into the account. The habits which we are now combating, are the vices of artificial life. And the love of nature is one of the best les- sons to a young scholar ; it checks every ex- cess, and prescribes nothing unwholesome to either body or mind. To see the grass spring, the plant shoot, and the flower blossom, are among the finest objects for contemplation. What ingenuous youth ever heard the bird sing, the lamb bleat, or the heifer low, but warmed with emotions of a superiour kind. 248 The beauties of landscape, more than any thing we view, purify the heart, refine the taste, and warm the feelings. All is cheerful, active, and healthful, because all is natural and innocent. Youth is the season of life to leain with advantage the value of nature's produc- tions, and picturesque scenery. If neglected then, the soil will groan under less amiable productions. To what an unfortunate change the present fashions are conforming mankind. The country houses of our nobility and gentry are empty till July. Thus the spring months, that season of joy throughout creation, passes unobserved by the affluent and gay. The souls of human beings in this age of art, would seem to wish the sun to be darkened ; they find no pleasure but in the light of a lamp or a flambeau. I feel for the rising generation, when I consider the effects of these over- grown follies upon unexperienced minds. With respect to the prevention of these dis- eases, in grown up people, or what is the same thing, correcting the predisposition, no task in medicine has more difficulties to surmount* It is not that it is impracticable ; but the pa- tients themselves, are seldom willing to sub- 249 mit to a code of rules for the direction of their health, and view with jealousy and pain every precept that is to subtract from their plea- sures. What reward can encourage the sloth- ful to activity ? Who can teach the voracious glutton moderation in eating ? Or what elo- quence can persuade the habitual inebriate to forsake his bottle ? Nay how difficult the task, to draw the nervous female from her tea! Where the predisposition is not hereditary, some of the causes which have been assigned, will generally be found to have brought it on. If these causes have been owing to any indis- cretion of the patients themselves, to counter- act them, will be difficult in proportion to their inveteracy ; and the desires and passions which give them effect. A habit is to break up, without which there are no hopes of relief. Every nervous person has some favourite pleasure to indulge. Articles of materia me- dica avail little, unless the patient forms the resolution to obey the injunctions of his phy- sician. To begin new modes of living ; to go to bed soon and rise early ; to drink water in- stead of wine ; to labour and toil, and be ex- 250 posed to the weather after years spent in luxu- ry and sloth, are changes not likely to be heard with satisfaction, far less to be practised with perseverance, by an enervated voluptua- ry. Yet changes equally great must be effect- ed, or there can be no recovery. The treatment of these diseases is a part of the physician's duty, that differs much from the experience necessary to direct with suc- cess, the practice in most other distempers. For, however well he may be informed by preparatory studies, and however stored with the resources of his profession, something will still be wanting to insure a decisive method of cure, which even the sick-bed cannot sup- ply. This is the knowledge of character and of mankind, which can only be learned by quick discrimination, and correct observations formed in the busy world. The living man seen in his varied pursuits, can alone bestow that knowledge on the physician. Fcr this very reason, there are no disorders that so puzzle and confound the young and inexpe- rienced ; and none so liable to «be misunder- stood by the ignorant, or plodding part of the profession. 25! The old maxim contraria contrariis medeti- ter, is better exemplified here, than in most other diseases. To change a state of body in- duced by long customs of living, or derived from nature itself, must be entered upon with •fortitude and resolution. But e\en where no improper habits have been formed, changes and variations of regimen that powerfully im- press the nervous system, and call forth active passions of a different kind, will often be ne- cessary to health. To the inhabitant cf a town, a country life rd the most salutary recreations. But that this change of scene should operate with - ter, with some salt of a purgative quality, as that of Cheltenham, in certain nervous and dyspeptick habits they are peculiarly useful. Where occasional icteritial symptoms prevail, from obstruction of the biliary ducts, whether from spasm, mucus, or other causes, which retard the peristaltick motion of the intestines by the bile being deficient,, such combinations of iron and purgative salt, have the best e£- iects ; as the laxative power of the one does not interrupt the invigourating quality of the other. Iron dissolved in water by the chem- istry of Nature, seems to act more powerfully by its extreme diffusion : and as in this state of solution, it is capable of circulating through the minutest vessels, its stimulant and strengthen- ing powers are exerted on the remotest parts of the system. Much of the operation of chajyheates may be by chemical union with the fluids of the body, but there can be little doubt that they also directly stimulate and ex- cite the nervous substance. In those persons where cold extremities and pale complexion indicate a languid circulation and poor blood, *. i O besides weak digestion, chalybeate waters of- ten perform wonders. But where there is much colour on the surface, and a florid blood, I think them improper. There are however many cases of nervous indisposition, for which the waters impregnated with the sulphurated hydrogenous gas, and a neutral salt, are to be preferred : such are those of Harrogate and Moffat. Where cutaneous eruptions or defaedations, are troublesome, or apt to alternate with the dyspeptick and bilious symptoms, these hepatised, or sulphurous wa- ters, seem the fittest. They may also, at the same time, be used as a warm bath ; and their efficacy in this way is known to be considera- ble. These cutaneous diseases are probably much owing to the inactivity or torpor of the absorbents, and perspiratory vessels on the surface of the body, over which this kind of water has a manifest stimulant power. I have often seen similar good effects from a pres- cription imitating the composition of these waters.* * Since writing this paragraph, I have perused a very sensible pamphlet, by Mr. Peacock, surgeon in 277 But while I fully admit the medicinal ef- fects of mineral waters in these diseases, I must still reserve a share of the credit to the relaxation and amusement that are to be met with, at these healthy and fashionable resorts of company. Taken together, and properly employed, they form a most important part in our preventive practice. I know not what would become of numbers of families in this country, were it not for the enjoyment which is obtained, once in the year, at some popular watering place. The time of leaving home is wished for with impatience ; and the avoca- tions and engagements which delight them abroad, make up the chief theme of conver- sation till the season returns. Darlington, announcing the discovery of a sulphurous water, at Dinsdale, in the county of D irham. This water, from the analysis given, contains a very large proportion of sulphurated hydrogenous gas : and its efficacy on the usual complaints, for which this kind of water is employed, has been confirmed by many trials. This little work contains many able and pertinent re- marks on cutaneous disorders ; and some striking facts, on their alternating with nervous and stomach affections. May, 1806. z 278 Nervous people ought to clothe rather warm, and guard against variable weather. If they are accustomed to flannel next the sur- face of the body, it must be often shifted: and the body ought to be wet-spunged, or sprink- led with cold water every morning, then wiped dry with a hard towel. Persons who practise this mode of lavation daily, know that cheer- ful spirits, an agreeable warmth, keen appetite and easy digestion succeed it. And when through indolence or forgetfulness they hap- pen to leave it off, their dyspeptick disposition loon gains ground. The feet of some nervous people are very liable to be cold; but this oc curs mostly with such as use no exercise ; for the sitting posture checks the circulation m the lower extremities, and also disposes them to swell. Stockings made of lamb's wool, laced stockings, or at least flannel socks, elastick gaiters, and hair or cork soles, make the pro- per defence in winter, for the heels and teet; and while they prevent chilblains in frost, they insure the pleasure of recreation out of doors, when the ground is damp. But where one person receives an injury to health from damp ground and thick fogs, a thousand perish by loitering within doors to avoid them. ^79 To such of the nervous temperament, as complain much of head-ache and virtigo, in full habits, with frequent heat and coldness of the head, accompanied with drowsiness and stupour; these symptoms in advanced life, are always to be dreaded. They particularly attack drunkards and great eaters, who are corpulent, have large heads and short necks. Persons of this description must correct their modes of living, if they wish to avoid a sudden death. Low diet, with entire abstinence from spiritous and fermented liquors, and much ac- tive exercise, is the best regimen for health. Bleeding, cupping, and leeching the temples, are sometimes required : but these can only be considered as temporary remedies, for fre- quenting blood-letting favours fullness of the vessels. The state of the bowels must be lax ; the sleeping room airy and cool ; suppers must be avoided ; the sleep should not be long, and violent passions of the mind must be guarded against. Where nervous diseases have been brought on by affections of the mind, misfortunes in life, or affliction of any sort, it is obvious they must be considered as partaking more of § 2S0 mental disorder. Change of scene in these cases, is commonly the first step to the cure: as by removing the distance of all objects that have a tendencv to refresh the memory, or cause association of ideas, that bring up gloomy reflections, you weaken the chain of sympathy, till it is gradually broken. It is the duty of relations had others, who may be in- liinately acquainted with the patient, to inform the physbiar. minutely of every circumstance ; for it must be in vain to prescribe for a mental disease, v.here we are kept in the dark con- cerning the cause. Every such case mu*t have its appropriate management, both on the part of the medical attendant and inmates. Such hallucinations of mind are always to be re- garded as threatening insanity or idiotism; and without a careful investigation of the an- tecedents, no physician can direct the treat- ment to advantage, or pronounce the issue. It happens too often, that the early signs of mental disquietude, which discover themselves first by peevishness of temper, and irritable feelings, have been misconstrued by relations: and a degree of harshness sometimes has been exercised upon the patient from a disbelief of 281 his disorder, and not foreseeing to what it was tending. The subject in all respects requires infinite address on the part of the physician : for petulent meddlers are more difficult to be managed than the deranged patient. To treat this stage of a serious malady with doubts of its existence would be deliberate cruelty. To mock their fears, however false, bespeaks cold- ness of affection ; and I have often seen it bring on intemperate sallies of rage; flattery answers better, for they have less jealousy where there is no attempt at disputing they are right. But there are moral and physical causes prompting these feelings, with an impulse not to be resisted : and while the mind is occupied with such sensations, it is in vain to persuade the patient that they have no reality. When people with low spirits are to be cheered and recruited by "conversation, it ought always to be conducted with delicacy; and this can ne- ver be duly managed but by a person of intel- ligence. If the mind, at any time is ruffled by neglect, where it expected sympathy, we run the hazard of seeing the whole regimen of health given up, and all confidence of at- tendance lost for ever. And when medicine is z2 282 directed, every argument must be employed to inspire hope of its virtues, and the certainty of its doing good. Here, as in maniacal cases, subjection and restraint have been frequently carried too far ; and the patients have been driven to despair, and ended their torments by suicide, rather than submit to the lash of their keepers. If insanity is purely a mental alien- ation, the method of cure must turn chiefly on a mode of discipline addressed to the weaken- ed powers of intellect. Such persons ought never to be left alone ; their train of thought should be constantly interrupted; for by in- dulgence it acquires growth and retention. I do not see how corporal punishment can be admitted, where the reasoning faculties have ceas-ed to exercise their authority, and where the living soul is not conscious of moral obli- gation. A physician who has to direct the treatment of maniacks, must live among them, that he may learn the genius of every indivi- dual case, if his discipline is to conduce to their recovery. There are certain forms and customs of living, practised by men who are commonly deemed models of temperance, , The striking CS3 part of a regular life, is an exact and correct division of time. Every hour of the day has its appropriate task ; and pleasure and dissipa- tion never supplant business and duty. The temperate man goes to bed before a late hour, and uniformly rises early. Hence early hours are another term for a regular and temperate mode of living: as the contrary bespeaks a life of frivolity and insignificance. Can any hu- man being be in pursuit of noble and elevated honours, who is found in bed at eight or nine in the morning ? Such a man never yet in the world, acquired the title of either good or great. It is therefore one of the most unpar- donable neglects of a family, where parents give the example of late hours to their children. What an insult to nature, to allow the sun to shine six hours above the horizon, before get- ting up ! Late hours at night, and long in bed in the morning, are among the nursing mothers of nervous complaints. A permanent and perfect cure is never to be accomplished, with- out forsaking these slothful habits: and to dis- card them is always a part of my discipline. The diet of a temperate man, or such as wish to be free from nervous and bilious com- 2*84 plaints, is plain food, and that in moderate quantity. A person ought to rise from table, cheerful, active, and refreshed with what he has eaten ; not oppressed, drowsy or unfit for motion. Where great quantities of strong malt liquor, or wine, are taken with dinner, the stomach becomes the more overloaded ; and sleep is called for, to be relieved from the burthen, as an instinct of nature. An appetite not accustomed to high seasoned dishes, or savoury meat, selects for itself what is whole- some and easy of digestion. Beef or mutton are better than veal or lamb; roasted meat not overdone is preferable to boiled; but broths not too rich or superseasoned with spi- ces, ought to be a daily part of every tempe- rate dinner. Nervous people complain of broths distending the stomach and occasioning flatulence ; but this is the language of sloth ; motion and exercise soon correct this kind of uneasiness ; and when the stomach has been accustomed to broths, no such effects can be perceived. The legumina, such as peas and beans, must be sparingly used at all times; they load the bowels and render them slow j and raw vegetables, as sallad and cucumber, . 285 are also improper. But pot vegetables in mo- derate quantity, are all mild and wholesome to be used with meat." Fish and poultry with- out rich sauces, may be allowed : and game on the same terms. All kinds of pastry and pye- crust are difficult of digestion, and prone to fermentation and acidity ; they lie heavy on the stomach, according to the common phrase: and bread, rice and custard puddings, are the only articles of that class that should be eaten, Sound biscuit, and light well fermented bread are to be used ; leavened bread, or bread ba- ked without yeast, ia weak stomachs, pro- duces acidity, heart-burn and flatulence. Co- coa or milk, forms the mildest fare for break- fast, which ought to be taken soon after rising, A very light meat supper is often necessary to amuse digestion : but gruels, sago, arrow-root, and such like, are improper, they run into fer- mentation, and partake of the unfermented farinacea. Water, or toast and water, is the best drink with meals; and milk and water at other times: cyder, perry, beer or porter, create distention, flatulence and heart-burn. The quantity of wine at, or after dinner, should be 286 s.nal!, and that diluted with water : Madeira when genuine, is the purest wine, and best suited to a gouty or dyspeptick stomach. Shrub, sherbet, punch, and every thing into i which an unfermented acid enters, are impro- per drinks : liquors, and spirits of every de- scription, are to be considered as Syrens, that charm the road to destruction, and ought to be rigidly abstained from. Nervous persons do best to dine off a few dishes ; and those of the simplest kind ; two or three articles at most should bound their repast. They are, of all mankind the most liable to surfeits ; and when they reflect, that the very weakest parts of their constitutions, are the digestive organs, they must either be sparing in their good things at table, or expect to be punished for their indiscretions. There arc iew of the number, who have not had ex- perience of this truth. Having recommended a milk breakfast, I am aware that many objections will be oppo- sed to it. I have been often told the stomach could not bear it. If a physician is pliant enough to yield to such excuses, he runs a poor chance of doing any good in these disor- 287 ders. This is the common language of per- sons who have worn out the excitability of their stomachs, by strong green tea and other improprieties of diet. The soft bland milk does not convey to them that warmth which they have been accustomed to receive from more stimulating fare. But let them be en- couraged to persevere ; and as this alteration of breakfast is only a part of a greater rever- sion in modes of living, it will not fail in the end to be agreeable. I must on that account caution them against any mixture of spirit, or even spice in their milk. But if the acidity af rwards should be troublesome, they may with ease correct it by calcined magnesia, or fifteen grains of prepared powder of chalk, as the bowels may be slow or otherwise. To young women of all rank-, the milk breakfast is peculiarly adapted ; and I have the authori- ty of Sydenham, that it is the best food for the gouty. From the experience which I have had, in some thousand of these cases, under all the Variety in which they usually appear, I freely give it as my opinion, that the only means of cwer lie in a total abstinence from every 288 species of spirit or fermented liquor ; from every thing that bears any analogy to them, such as tea, coffee, opium, and all other narco- ticks ; and to regulate the diet, cloathing, air, exercise, and passions, as becomes a rational being. The improper use of these articles being the chief cause of nervous indisposition, it follows that no recovery can be perfect, till they are in toto discontinued. Attention to the state of the bowels forms an important part of the prevention : but if due regard is had to air, exercise, and diet, even habitual constipation may be overcome. What relates to its relief otherwise, will be noticed in the proper place ; but if the food can be so regulated as to supercede medicine, it is an important point gained. The whole of the precepts which have been delivered, as the means of prevention against this singular train of diseases, it will be readily perceived, turn upon a reversed mode of living, or changes opposed to former habits ; and to bring our patients back to a simple regimen of food, air, exercise, &c. Our plans compre- hend no favourite theories, nor any intricate doctrines ; they aim at being natural, simple, and easy to be understood. 28£> Some striking instances of the beneficial effects of these rules, when entered upon with a determined spirit, have been proved in my own practice. A few years ago, when it was my good fortune to be honoured with unboun- ded confidence by the naval service, I was consulted by some particular friends of great affluence, on the bad health of their wives, who, to the regret of all connected, had never been in that happy way, " Which ladies wi$h to be, who love their lords." These ladies, after being married for several years, without having children, devotees of fashionable life, and a prey to painful nervous disorders, are now the mothers of healthy boys and girls, and enjoy the best health imagina- ble. All these happy changes were effeced by little assistance from medical prescription ; they were brought about by reversed modes of living. A few visits to their town friends, and an equal number to a provincial assembly, are all that these once gay parties now see of the fashionable world. What married woman could refuse to quit a life of late hours, insipi- 2 A 290 dity, and dissipation, for such tokens of happi- ness and health ? Change of climate is one of those means of relief in nervous cases, that may sometimes be resorted to with great advantage. There are nervous persons who are most sensibly af- fected by variable weather ; where the transi- tions are quick, particularly from settled and clear, to damp and foggy. The human nerves in such patients are like barometers : it is thus the fall of the year, in November and Decem- ber, is proverbial for lowness of spirits and melancholy, A residence in Italy, or the south of France, for some time, may therefore be useful to such as can afford it. But it must be remembered, if these persons return to Britain wiihout having made great changes in the dis- cipline of health, they must expect fresh at- tacks of their complaints, A climate not too warm, where the atmosphere is clear, and the temperature equal, or not liable to extremes, is chiefly to be preferred by such people. Here again the change of scene may have a powerful influence on the mind. From the effects which these diseases are known to produce on the spirits, there is a mo* 29X ral regimen, as it may be called, necessary for our patients, and which must remain with themselves. The person who is subject to nervous affections, can seldom promise him- self long equality of health and spirits : these vicissitudes must often happen, from causes which neither could be foreseen nor prevented, and sometimes when least to be suspected. The mind however is not slways prepared to combat sensations that impress it with ideas of dissolution ; otherwise it could not so fully believe in imaginary horrours. It is a singu- lar fact, that even men whom I have known, renowned for valour and personal courage, and who have been familiar with danger, should sometimes be found among the number of those who conceive such dread from indis- cribable feelings, and torture themselves with a phantom. When these hallucinations come to be removed, they can condemn the imbe- cility that created their fears ; yet neverthe- less on a next attack their apprehensions are renewed as strong as ever. The judgment being thus perverted for the time, the false per- ception is to be considered as a degree of deli- rium and temporary insanity. When the pa- 292 tient perceives the first approach of these odd feelings, he ought to turn his atteption instant- ly, to the recollection of such scenes and ob- • jects, as he has been accustomed to contem- plate with much pleasure, and review with sa- tisfaction : there let him rivet his memory, and if he can raise it to extacy, he will infalli- bly subdue the morbid associations, and the frightful images which they present to the mind. This kind of mental controul will be difficult at first ; but we have known patients who became quite adepts in the practice of it, and secured themselves from many painful Struggles. It so unfortunately happens in these moments, that bad actions and subjects of affliction are most apt to occupy the memo- ry : hence it is that wicked men are said to have suffered the pains of hell in this world. Some nervous people, in this state of derange- ment, have so magnified their own guilt, as to make formal confessions of crimes they never had the most distant idea of committing. If when in company, and any thing hap- pens to be said, which brings to recollection any distressing circumstance, the nervous in- valid, must either retire, or the conversation 293 must be changed. And such of them as live much alone, must endeavour to regulate their train of thinking, so as to turn it quickly, the moment any thing disagreeable is called up to memory. I once witnessed a very affecting scene of this sort: a gentleman in company repeated a line from Cato, " Welcome my son ; there lay him down, my friends." A lady in the room, who had lost an only son ten years before, was immediately thrown in- to violent hystericks, that had nearly proved fatal. The habit of breaking up these associ- ations gives a new relish to life ; while the want of resolution makes nervous people so frequently their own tormentors. And when they acquire this manner of self-government, if I may so speak, it is surprising what confi- dence it gives to the mind.* * For the following anecdote of Dr. Cullen, I am obliged to the late Mr. Whale, rector of the grammar school of Kelso, an eminent scholar, who had lived in Hamilton, where Dr. Cullen once practised. Dr. Cul- len was subject to gout, and possessed thereby the pre- 2 A 2 294 As mankind in these diseases, are so often the authors of their own misery, compunctious visitings of nature must frequently recur. In such conditions of affliction, I do not see that it is at all out of character for the physician to administer even what is called spiritual com- fort. A medical friend who may know the value of religious duties in his own life, can- hot be an intrusive monitour at a time when distress opens the avenues to the human heart; and when his professional visits necessarily attach confidence, which cannot be reposed in a stranger, and who may be less conversant in disposition to nervous affection, and often suffered from demisaio animi. He had a severe attack of low spirits, perhaps brought on by narrow circumstances, and great application to business and study ; when he was surprised in his lackadasicat mood, by a friend coming in—" I am very ill indeed," said the doctor. The gentleman endeavoured to divert him from his glooms : Do you never build castles in the air, by way of amusement, Doctor ? " O no, I have not even strength for that." Did you never imagine yourself a great general, leading victorious armies to battle, and enjoying a triumph ? " No, by----! not evea ia imagination did I ever fancy myself a soldier l'[ 295 those failings that sometimes bend the strong- est. There are also certain delicate situations with low spirited people, that make a formal visit from a clergyman impracticable, however much it may be wished for otherwise. I be- lieve it is a common remark of the profession, that on the sick-bed, we observe more forti- tude of mind among women, than is to be found among men. We must attribute this excellence in the sex to superiour virtue'; and to their being educated more in domestick life, where religious and moral habits take deeper root, by being less corrupted from intercourse with the world. Persons liable to these diseases, must be cautious how they plunge themselves into any affairs or business, where crosses or disap- pointments may irritate the temper. As they are commonly subject to sudden gusts of pas- sion, a prudent and guarded command over them, is the only security for tranquility of mind, and a smooth passage through life. The nervous frame must, therefore, trust to self-regulation, in a great measure, for exemp- tion from many painful affections, over which the powers of medicine have no controul. 296 Having thus finished the means of preven- tion for nervous diseases ; or what may be called the mode for correcting the predisposi- tion, it will readily appear that the whole of our precepts have an equal ■application against the arthritick diathesis. If gout can be pre- vented at all, it must be by a rigid adherence to simplicity of living ; whether in air, exer- cise, food, cloathing, passions of the mind, &c. and to avoid all excesses and debilitating plea- sures which are known to enervate the general frame, or weaken the chylopoeietick organs. I know of no distinction that can be drawn be- tween the habits of body that give birth to gout and nervous diseases, beyond what has been said in the preceding part of this work ; and it appears that the most successful prevention of both, will much depend on its being enforced from the birth, and continued through life. The gouty constitution is certainly injured by every excess of stimulus, like the nervous tem- perament, but particularly narcoticks of all de- scriptions. If any fact more than another has been proved in my own practice, it is that spi- ritous liquors, and all wines, with tea, opium, mercurial courses, and the sexual indiscre- 297 tions, are the chief causes of the acquired predisposition that equally engenders both these diseases. I come now to the treatment, that may be called more strictly medical. And it is to be remembered, that the whole of the precepts, which have been delivered under the preven- tion, are to be duly attended to during the use of medicine ; for unless regard is paid to them, articles of Materia Medica are not only of no avail, but may sometimes do much harm. Though I repose due confidence in medi- cine, when well timed, it is to be observed, that here the practice i^Hrected against a dis- eased state of sensation and motion, brought on by causes which exert a peculiar influence on the nervous system: causes which invert all the regular operations of a most complica- ted set of organs ; and in the cure of which the common resources of our art seem to lose their usual power. Those cflfctoms and habits which form as it were a part of Nature in the 298 living body, are to be counteracted by rever- sions in diet, air, exercise, and even mental regimen, great in proportion to the morbid af- fections they are intended to overcome. In the body we observe symptoms, that counter- feit every other disease, forming a part of this assemblage ; and in the intellectual functions we find disproportionate emotions and the most extravagant illusions. The indications of treatment may be divi- ded into two heads : I. To strengthen the constitution. II. To palliate particular symptoms. 1. To presricbe for a class of diseases so variable in appearance, and equivocal in their smyptoms, requires a full share of experience and discernment, and not a little patience in actual attendance. The physician must often take a very circuitous route to put questions to his patients, that he may learn the real genius of the distemper. He must in many cases be guarded in his inquiries, lest he excite fears and suspicions in the, irritable mind, which is observant of every trifle, jealous of a whisper, and when once aJfermed, however falsely, not easily quieted again. 299 I have generally found it the best way to be candid and open in my opinions with nervours people. It is th^'conduct which will insure most satisfaction in the end, whatever tempo- rary embarrassment it may occasion. And I have never found it improper to inform them of every article of medicine prescribed, and to explain the effect I expected from it. By these means they will not be taken by surprize ; for if they find themselves deceivflH once, their confidence will not be easily regained. This demeanour becomes the more necessary, as they are very apt to listen to stories of won- derful cures, and to pore over medical books, that they may compare the opinion of their physician with what they imbibe there. In the treatment, it is always to be consi- dered, how far these diseases are the primary complaint, or idiopathick; or how far symp- tomatick, and excited by another disorder. Wherever the body has been reduced to great debiniy, the leading features of a nervous temperament when present will appear : and the method of cure for the original disease, must conjoin with it the appropriate treatment of nervous affection. Many females, with a 300 delicate and irritable nervous system, at the period, experience more or less of these com- plaints ; and they subside with it. If they were even severe for the time, we are ac- quainted with the reason : and it would be im- proper to harrass the patient with quantities of medicine for symptoms, that we know must decline in a clay or two, perhaps in as many hours. Similar cautions must be used, when from any cause the menses cease, and severe nervous affections supervene. This may hap- pen from pregnancy ; and the treatment must be guarded accordingly ; for all the signs of breeding are from sympathy between the ute- rine system, and the chylopoeietick organs. The lying-in state, even under the most fortu- nate circumstances, will, for the same reasons, be often marked by a recurrence of nervous complaints. In such situations it is impossi- ble to lay down rules, as the practice must va- ry according to the peculiarities attending, whether from severe and lingering labours ; excessive flooding; puerperal fever; impro- prieties of diet or regimen; passions of the mind ; milk fever ; diseases of the breast, &c. all of which will bring forth nervous affectiona 301 of the most afflicting kind, such as frequent syncope, cramps, convulsions, delirium, &c. I was lately called to visit a woman, where the midwife had taken away sixteen ounces of blood, under the idea that a pain of the side was a pleurisy: delirium commenced imme- diately, with violent convulsions ; and the pa- tient died in forty-eight hours from the bleed- ing. In no conditions of a diseased state of body, are mistakes of the nature of a com- plaint, so liable to lead to fatal consequences as in the puerperal patient. Married women who have never borne children, it is said, are more liable than mo- thers to these diseases. The nervous female commonly finds her health improved when she becomes a parent; from which it may be fairly inferred that the child-bearing period is fa- vourable to the constitution. Every intelli- gent mind knows well, whatever cares a fami- ly may bring with it, they are more than over- balanced by the sweet solicitudes of affection which spring from them. Hence every wife wishes to be a mother: the want of children thus grows to a misfortune, and those motives i for energv of mind are neglected. But if this 2 B 302 misfortune has been owing to nervous indispo- sition, brought on by any cause which has been assigned in these pages, if it is at all re- mediable, the means are obvious and easy to be employed. When these diseases appear about the age of puberty, at a season when delicate changes take place in the system, we are then aware of the event, and can calculate upon their de- cline. Their appearance at this time of life, is marked by a singular train of phenomena, all depending on a mobile condition of nervous power, as the body acquires the possession of new passions and faculties. The generick names of chorea and chlorosis, have been given to these diseases; but I hold them nothing more than traits of the nervous temperament, Chorea or St, Vitus^s dance, commonly begins some years before the age of puberty; and in both sexes it seems to decline as soon as the body has acquired its stability, and the sexual organs are fairly evolved. It consists of invo- luntary motions of the extremities, and some- times of the muscles of the face, appearing like antick tricks and gesticulations ; but there is also more or less of dyspepsia. I have seen 503 some instances where convulsions and deliri- um of a singular kind attended this disease. The predominant symptoms of chlorosis are muscular debility, sallow skin, indicating deficient oxygen in the blood, and great de- rangement of the chylopcsietick organs, with other symptoms of dyspepsia and nervous af- fection. Thejre is commonly a desire for eat- ing dust, chalk or lime, and probably depend- ing on excessive acidity in the first passages. As this complaint chiefly appears about the age of puberty, it has justly been considered as having some connection with the evolution of the uterine system: and years of bad health sometimes follow, before the meustrual dis- charge is duly established. With this all the dyspeptick symptoms disappear ; the mamma? swell, and the countenance resumes its rosy colour; the body recovers its muscular strength, and the shape is moulded into all the softness of form and beauty. But at the same time, it ought to be remembered, that the male constitution, at puberty, is also frequent- ly subject to chlorotick indisposition. As cho- rea and chlorosis, indicate the presence of the nervous temperament, I have nothing particu- 304 lar to offer on their treatment; it falls entirely in with our general plan. These complaints are another confirmation of that intimate sym- pathy which subsists between the sexual or« gans, and the chylopoeietick viscera. There can be nothing strange in these symptoms ap- pearing in an aggravated form at this age, where the nervous power is very mobile ; for we find other symptoms sometimes at an ear- lier period, that are usually considered as the disease of riper years, namely, the fluor albus. I have at this moment two children of seven years of age, now convalescent of that com- plaint, with all ihe signs of hereditary ner- vous predisposition. In directing forms of medicine for our patients, there is one rule must be carefully attended to, not to sicken the stomach by be- ginning with a large dose. If the digestive organs in their deranged state are incapable of acting on the food, how much more may they be oppressed by a nauseous medicine. This article, as well as the diet, must undergo the digestive process, if it is to be useful ; and it is the business of pharmacy so to prepare it, that it may best answer this purpose. It is not 305 that a medicine is to be sweetened to cover its bad taste, or warmed with spirits, that it may afford a grateful stimulus to an exhausted sto- mach : it must be exhibited in a state where its powers may be most effectually exerted on the nerves of that organ ; or so easy of decom- position, as to combine readily with the ani- mal fluids, and yield its qualities to be convey- ed by the circulation to remote parts. t Cincho- na, or Peruvian bark, so often prescribed in nervous and dyspeptick cases, has been some- times given to the amount of two ounces/in substance in twenty-four hours ; and because the stomach did not reject this enormous load by vomiting, it has been triumphantly ex- claimed, that large doses only could do good. Such a quantity could only produce torpour and insensibility ; its active qualities could not be exerted as a medicine on the gastrick nerves, for what solvent in the stomach could effect its decomposition. For my own part, I have never met with patients who could retain such quantities of bark. It appears to me much more rational to begin with small doses, and to watch its effects. Hence we learn that de- coction and infusion will sometimes succeed, 2b2 30G when the powder has failed. These forms seem to derive still further power, by being conjoined with some of the alkilies, the carbo- nate of lime, (chalk,) or magnes. ust. all of which not only increase its activity, but make it to sit easy on the stomach. The pharma- ceutical treatment of most of the bitters more or less resembles that of cinchona. It is sometimes necessary to premise ai>o* mitor purge, or both, before the use of strength- ening remedies, as the stom ach and bowels in their irreguiar state are often loaded with phlegm and mucus to a surprising degree. Besides, the capricious flow of the bile into the duodenum, is often the means of render- ing different portions of the intestinal tube tor- pid, or irritable, as it happens ; and an active purgative will always have considerable effect in restoring the equal motion of the bowels. As an emetick I prefer the ipecacuanha, to be assisted by a weak infusion of camomile. As a gentle purgative I prefer rhubarb ; and when a quicker one is required, I employ pulv. jalap. With each of these I uniformly combine mag- nes. ust. kali or soda. These not only correct acidity, in the first passages, but also render 507 the active part of the other articles more c'e'f* tain in their operation; they also become sol-» vents of the animal mucus so often accumula* ted there. After the pfimaevise are thus cleared, wc may with safety begin the corroborant medi- cines; being always cautious in selecting and combining them with such stimulant and ad- juvant ingredients, as may make them easy to the stomach, and adapted to the constitution. It is impossible to lay down rules for what is to be directed by experience in every indivi- dual case : but it will often happen, that the same article which does harm under one for* mula, will be eminently useful in another. And in suiting the medicine to the exact con- dition of the stomach, the success of the prac- tice will be more or less complete. The phy- sician will but too often find reason for remon- strating with his patient on neglecting his in- junctions, whether in air, diet, or exercise : a watchful eye must therefore be kept over the regimen, that medicine may not fall into un- merited discredit. The strengthening medicines which have been chiefly employed in these diseases, are 308 iron, Peruvian bark, and bitters; but zinck, copper, and even silver and lead have been used. And the mineral acids, the sulphurick, nitrick and muriatick, have on some occasions been deservedly praised in many dyspeptick stomachs. Iron very properly is considered as the first article in this class. Its reputation is ve- ry ancient, and physicians have been uniform in extolling its powers -r they are certainly in some shades of these diseases truly wonderful- There are few of our patients whose habits of body contra-indicate its exhibition ; but it is eommonly forbid where there is much strength and tension of muscular fibre, and a florid dense blood. Such a state of body is seldom met with among the nervous, bilious and dys- peptick ; but we have frequently been obliged to lay aside the use of chalybeates for the very reason just assigned. Sydenham, who seldom erred in practice, preferred iron in its metalick or oxide state, to all its other preparations. I can readily join in the praise which the English Hippocrates pronounced on this celebrated strengthener -r but there are certainly conditions of the sys- 309 tern in nervous diseases, where some of its sa' line combinations are to be preferred. In! some female habits where there is vast dispo- sition to acidity of stomach, the limatura ferri, and carbonas ferri, will act most powerfully. And there is reason to suppose, that this very acidity of the primse via?, further oxydates the metal ; by that means destroys itself, and leaves the iron in a more active state to strengthen the fibre, or to mix with the blood, and exert its efficacy on the whole circulation. But in cases where there is little or no acidity in the first passages, the muriated tincture of iron, and vitriolated iron, have appeared to me to have manifest advantage. Again, in cases where there is much torpor, or as you may call it, sluggishness of fibre, and coldness of constitution, with acescency, then the ferruni ammonicale, or the tincture made from it, are of superiour efficacy. Some of the most for* tunate recoveries which ever occurred under my own prescription, were effected by the fer- rum ammonicale. In these cases, violent pain of the gastrick region, occasional jaundice, fla- tulent cholick, shifting spasms of the whole abdomen, vast acidity, vertigo and head-ach, 310 &c. were the predominant symptoms. Yet most of these cases were reduced to the last degree of debility when I first saw them. Certainly in stomach and bilious complaints under extreme weakness, very unexpected re- turns to health sometimes take place by a fortunate change of medicine. It must there- fore be a point of nice discrimination in the practice, to suit the preparation of this metal, to the exact disposition of the disease, and the idiosyncrasy of constitution. When I employ chalybeates of any des- cription, it is usual with me to precede their use, for a few days, with some preparation of bark or bitters ; and to continue them for two or three week^s with the ferruginous medicine. After a short interval they may be again re* newe'd, as circumstances require. In this manner the two articles will effect what nei- ther of them can do*alone. But I am of opi- nion, with many other physicians, that ferru- ginous medicines of all kinds, ought to be con- tinued for a length of time, if full benefit is to be derived from them. Even where the good effects are early apparent, they must not be too soon laid aside : from three to six months are 311 often required to insure all the good that may be obtained. All the different forms of iron are apt to make the bowels slow ; which with some patients is a constant objection to their employment. Even the sagacious Sydenham went so far as to say that laxatives ought not to be given during their use, as weakening their efficacy. It is however to be remember- ed, the diet of Englishmen in his days, was not so full and pampering as in the present times. This opinion of Sydenham has howe- ver had very little weight with me : I not on- ly interpose laxatives during the use of iron, but sometimes order a smart purge at inter- vals ; and so far am I from thinking that it weakens the power of the other medicine, I have always thought it necessary for securing its best eflicacyi The office of the intestines must be preserved regular in such patients, if any good is to be done. The kali tartar, is perhaps the best purgative article at this sea- son ; and it may have some action on the cha- lybeate that we cannot well explain. If, how- ever, our regimen of air and exercise is strictly complied with, there will be the less ne- cessity for forcing the bowels with medicine. ?i*! When iron is adapted to the case, the good effects are first observed, in the decline of the dyspeptick feelings : the calls of appetite be- come more frequent; the food digests with more ease, and acidity and flatulence cease to be painful. At this time the colour of the face improves, and grows florid; and the skin from being sallow and dry, becomes better coloured, soft, and perspirable; the al.vine faeces are commonly tinged during the use of iron,. With these changes, strength of body and alacrity of mind soon appear. In delicate females, some weakening sexual symptoms quickly decline. The indisputable good effects, which have so often resulted from a trial of Bath zvaters, in many varieties of these diseases, render it almost certain, that these have been produced by the ferruginous principle which they pos- sess ; but which is only effectual at the foun- tain, as it soon precipitates, and cannot be pre- served. As we perceive this metal when arti- ficially managed, to effect surprising changes in the animal economy, it is but fair to allow, that much more may be expected from the fine chemistry of nature. It is in vain to de- 313 vry this, because the Bath water contains an extremely minute portion of iron, discovered on analysis : the effect must rest on the acti- vity of the ingredient, whether in the state of oxide or not, not on its quantity. The sensi- ble qualities of the water, when drank on the spot, are highly ferruginous ; and the stimu- lant power is so perceptible, that in some ha- bits of body, it is dangerous ; inducing tempo- rary fever and vertigo, and in some instances apoplexy. The torpid habit is, therefore, most relieved by them ; persons worn down by the diseases and excesses of tropical cli- mates ; and those debilitated by luxurious and hard living at home. The regular hours, cor- rect manners, and elegant pleasures of the company at this fashionable place of resort, become the best antidotes in life, against li- centious drunkenness : no wonder then the enervated debauchee should return healthy, and sometimes reformed, from a course of Bath waters. But when nervous, bilious, and dyspeptick complaints depend, as they often do, on a gouty diathesis, Bath waters are a sovereign remedy. The energy which they quickly impart to the chylopceietick organs, is 314 soon extended over the whole frame ; and all those anomalous symptoms, usually called fly- ing gout, seem to rally to a point, and cease when the affection comes to be fixed in the ex- tremeties. I am thus induced to mention these salutary springs, under the method of treatment. With respect to the effects of the prepara- tions of zinck, copper, silver, and lead, which have been tried in these diseases, excepting the first, I have little experience of them. I have frequently combined the oxide of zinck with carbonas ferri, and other forms of iron, certainly with great effect; but not more than what is daily seen of iron by itself. A farmer lately brought his son to me, who by the de- scription, had been subject for six weeks to fits three or four times in the day, that were epileptick. He said he was returning at night to his father's house, and in a thunder storm was struck down by lightning. He was an hour and half in getting home, though not more than a mile from the place ; and being insensible did not know where he was till mor- ning. I found he had an hereditary nervous temperament, and many severe dyspeptick 315 symptoms. I ordered iron, ainck, and cincho- na, in the form of electuary. After the three first doses, the convulsions ceased : but he took his medicine only a fortnight, and the fits returned. He refused to go on with it, and I saw him no more. In this case I was guided in the practice by the dyspeptick stomach and predisposition. Of the cuprum, argentum, et plumbum, I have no experience. The iron is my grand safety. I fancy the resources of materia medica are sufficiently abundant at present ; the best physician must be he who can best select, and best prepare what we now possess. The cinchona, or Peruvian bark, stands foremost in our list of medicines taken from the vegetable kingdom. No article of materia medica has acquired equal reputation ; but it is the fate of this medicine, to be often dispen- sed from the hands of ignorant people, where neither the disease, nor the nature of the barfc, are understood ; and it must frequently do harm. Some attention ought certainly to h% paid to the manner in which it can be exhibit- ed with most effect. The powder has been said to be the most effectual form, but there 316 are many stomachs that cannot bear it in sub* stance. If, therefore, small doses do not sit easy, the infusion or decoction must be tried ; and it is the best way to begin even these in small quantity. To exhibit the bark in tinc- ture in these complaints, is an inconsistency in practice : it is no doubt very grau-fu! to some stomachs, but let us remember we are pouring into the body one of those narcoticks, that is daily bringing nervous afflictions upon thou- sands. It is, however, sometimes necessary to add a small proportion, to preserve the wa- tery preparation from spoiling. It frequently happens that bark acts purgatively, and passes rapidly through the bowels ; and laudanum has been the common corrector of its purgative quality. But I object to opium in any form, in these diseases, unless we are compelled by urgent pain. I have always found creta pre- parata, sufficient for this purpose: for it would appear that this effect of bark is chiefly to be met with in those subject to great acidity. I even find it necessary to combine ammonia with bark ; as bbth chalk, magnesia, and the fixed alkalies, are sometimes incapable of subduing the vast acidity in the first' passages ; and I 317 think this is frequently one of the best addi- tions to the other. In my own practice I have long considered these anti-acids when well timed, as the cause of my success. With re- spect to aromaticks, as adjuvants to either the bark or bitters, their good effects are very doubtful with me. I wish to exclude from medicine, as well as diet, every thing that is warming ; and I have a strong suspicion that aromaticks invert the action of the fibres of the cardia, or upper orifice, and thereby occasion belching, which is falsely said to be useful. When the extract of bark is genuine and recently prepared, it will be found in some ca- ses, to succeed, where milder forms of the medicine have failed. I have given it in both pill.and solution with great effect. I combine the pill with a third of gently calcined soda ; and I think, by thus converting the extract in- to a kind of soap, the solution of it in the sto- mach is more certain and equal, and the effect much increased. This form of pill answers very well with all the bitter extracts, such as gentian, chammomiie, &c. The distilled wa- ter of peppermint forms a good vehicle for the solution, and the extract mixes perfectly when 2c2 318 a due quantity of kali prepar. is triturated with it. When bark or bitters produce constipation, laxatives may be aptly joined with them. I prefer rhubarb and jalap, though I have no ob- jection to kali tartar. Next in power to cinchona I reckon angus- tura bark. This article has not been long in use in this country j it is certainly a valuable addition to materia medica. It is a rougher medicine than the bark ; and ought to be given in smaller doses ; and in those stomachs where it sits easy, it acts powerfully in subdu- ing dyspeptick symptoms. It may therefore be proper to begin with infusion and decoction, joining to them magnesia ust. and the alkalies, as in the pharmaceutical treatment of bark* Angustura, from its astringency, is more apt to bring on constipation than bark, so that some of the milder laxatives such as kali tar- tar, may be advantageously taken with it: and for this reason it is better adapted to those pases of nervous affection, where ft laxity of bowels forms part of the disease. It is also an excellent anthelmintick, and may be given to children subject to worms, in the morning fas- 319 ting, triturated with magnesia and soda, prece* ded and followed by a brisk purge as directed before* The gentian root is perhaps one of the best pure bitters in 'this class of diseases. The compound infusion of the Pharmacopeia Lon- dinensis, is the most advantageous form to employ it, to which may be added magnes. ust* carbonate of lime, or the alkalies. When bit- ters are first tried they are apt to sicken some stomachs : but this should be remedied by les- sening the dose. It is true that a pill of ex- tract of gentian and soda, as directed before, is more easily taken ; but I think by this change we lose considerably in the value of the medi- cine. All bitters seem to act most powerfully when largely diffused ; where there is much acidity as the effect of fermentation of the food, with great flatulence from the same cause, they produce very sudden relief. It is known that bitters chemically check the fer»- mentation by some antizymick power, and cor- rect acidity by the same means. I never perr mit the use of any of them beyond sixteen days at a time. Colomba root has become a favourite medi- 320 cine in these diseases, with a number of physi- cians in this country. It is certainly a very agreeable bitter, but I think in effect less than gentian. It has been said to be particularly- useful in bilious cases ; but ff does not appear even in tha^t trait of the nervous temperament, that it surpasses other bitters, however suc- cessfully given, where there is much uneasi- ness from* indigestion, acid eructations, and distension. I would recommend the same pharmaceutical treatment of colomba, as men- tioned of gentian. Chamomile, santonicum, wormwood, quassia, he, are all of the bitter class, and resemble one another in virtue. It is certainly an object in practice to chuse the most powerful, which is gentian. A very valuable addition is now made to this class by the salix latifolia, which answers well in de- coction to be taken with any of the ferrugi- nous preparations. Articles of the growth of our own soil ought to be encouraged by all me- dical people. See an ingenious Essay on this medicine, by Mr. Wilkinson, of Sunderland. 2. I come now to the second head of treat- ment, viz. To palliate particular symptoms. This is sometimes a difficult task in these dis- 321 ' eases ; as what tends most to give immediate ease, is what must inevitably have the effect of increasing the predisposition, and endanger- ing the return of the cofnplaint in a more ag- gravated form. Such I conceive to be the ef- fects of ardent spirit, opium, and all other narcoticks. Tu a person who reflects proper- ly on the horrid effects of dram-drinking, no- thing can be so disgusting as to see spirits swallowed in an undiluted state. It is there- fore my solemn opinion, that they ought never to be resorted to on trifling occasions j for when often repeated, even in the hands of the most cautious, they cannot fall of injuring the stomach. They moreover undermine health by favouring the attachment to spirituous li- quors. And such is the effect of opium, that many women subject to hysteria, are very apt to be seized with a fit, whenever they take a dose of laudanum. I have known numberless instances of this kind ; even epilepsy is some- times the consequence. Other women I am acquainted with, who never can use opium in any form, without a temporary delirium of the most disagreeable kind, and followed by sickness at stomach still more distressing* 322 These extraordinary effects chiefly arise from great mobility of nervous system. Too much caution cannot therefore be bestowed, to avoid temporary palliatives, that must ultimately produce permanent pain. In the course of my passage through the world, I have at different times known some fashionable women in high life, of the nervous temperament, who had got into the baneful habit of using opium as a cordial. Some of them were so familiar with it, as to carry a vial of laudanum constantly with them : a long evening could not be passed abroad with- out retiring to repeat the dose. The conse- quence of all this, as must be readily imagined, was continual bad health. Though none of these ladies were beyond middle age, yet they had all the looks of old women. It must be a grievous stain on the medical character, if such habits took their beginning fiom any in- considerate practice of a medical attendant. I am afraid the profession is not free from this imputation. A man who carries for ever on his face the sleek simper of artful insignifi- cance ; who has a bow and a smile ready for tvery person that addresses him, will be very 323 apt to accommodate his prescription to a fa* shionable folly. The first step to health is to avoid the cause of disease. But there are some physicians who contend that it is hurtful for habitual drunkards to leave off the bottle at once. Were the habit of dram-drinking a salutary practice, there might be some truth in this dictatorial prescript* But as ardent spirit is a strong poison to both soul and body, and forms no part of that nourishment which can be con- verted into animal matter, I have never been able, after the most unwearied application in the exercise of my profession, to find a single fact in support of a doctrine so destructive to moral and physical health. Whenever I have known habitual ebriety completely overcome, it has been where all species of liquors were given up in totofrom the first. The most painful symptoms which attend nervous indisposition, are those cramps and spasms, which particularly affect the stomach, bowels, kidneys, ureters and bladder. In the female subject they are most apt to occur at the period; and often commence in an instant. Such women ought to be carefvil about the *24 ♦tateof the bowels and stomach at that time, with respect to the kinds of food and the al- vine discharge; so as to obviate acidity, fla- tulence, &c. the painful companions of that state. The amenorrhea, or suppression, from whatever cause, is also remarkable for the recurrence of these symptoms, which are seldom fully relieved till regularity is restored. The condition of mind is worthy of great at- tention at that time ; for every ruffle of passion creates mischief. The warm gums, as they have been called, have been long in use for these troublesome pains and other nervous affections. They have been administered in the form of pill and tincture; not without some confidence being given to their unpleasant flavour, a singular way of prejudging the effects of a medicine. In nothing have I been more disappointed, than in the foeted gums; and where they have been apparently useful, it was probably from the spirit taken with them. Like aromaticks, they cause eructation, which is said to be a good effect; though with me an opinion that they invert the fibres of the cardia, which is improper. Asafociida is the foremost of this I 32£ list; but it ought to be remembered, that its tincture in the modern pharmacopeias, is made with alcohol; and a teaspoonful or two, how- ever diluted, comes to be a tolerable dram. Here the alliaceous flavour is very strong and impregnates the breath. In the form of ene- ma I have however known the asafcetida very Useful. Castor, ol. animale, and musk, are prescribed for the same purpose as asafcetida : but though they may possess a stimulant pow- er, it is very trifling and transitory; they are moreover, apf to disorder the stomach and bring on vomiting. Camphor and ammonia are of much greater value in nervous pains ; and their effects more permanent. ./Ether is also a common remedy, and when joined with opium and ammonia, of great service. This is a judicious mode for exhibiting laudanum, for a smaller quantity is required than when given alone. Valerian is another of the foetid tribe, frequently ordered in large quantity, to the manifest injury of the stomach. I believe it to be a very inert stimulant. As opium is known to produce a slow state of bowels, ext. hyosciami nigri, which has a laxative quality, was long ago recommended by Dr. Whytt in 2d 326 these disorders. We certainly by this change get quit of some of the bad effects of the opium ; but hyoseiamus extract must be re- cently prepared to be active ; and there is some difficulty in ascertaining the dose at once. But when pain and restlessness come to be urgent, and where common harmless re- medies fail, there is no resource besides opium% We know its sovereign powers as an anodyne, And we must compound with its bad effects in the best manner we can. We ought to combine it with such articles as co-operate with it, such as aether and ammonia, and the best vehicle is the mist, camphor of the dis- pensatory. But it often happens that the sto- mach rejects the liquid medicine, and the dry opium may be substituted, I prefer the mode by enema; and we may combine diluted spirit, or some of the stronger white wines with it, such as Madeira or Sherry, to great advantage, J have never been disappointed with a clyster of this sort. This also in a great measure paevents sickness at stomach afterwards. Some other symptoms which come on sud- denly in nervous cases, such as vertigo and head-ache, palpitation and faintness, do not 32? admit of such easy relief. They commonly attend some disordered state of the stomach and bowels, and to these the medical regimen must be directed.* The hysterick and epi- * I was lately consulted in a remarkable case of palpitation, in a girl of eight years old. The motion was so violent it could be seen at a considerable dis- tance, and it was constant, though somewhat increased by violent exercise. It appeared hopeless from the idea of organick affection in the heart: but the girl was in general bad health, and of a strongly marked nervous temperament. I therefore directed my advice to correct the predisposition, which was chiefly to the relief of the stomach. The next time I saw her the complexion was entirely changed ; she was grown flo- rid and beautiful, and full in flesh. I now think ex- treme irritability in the heart, with nervous weakness, was the whole disease. Similar cases have come un- der my observation, but none so violent as this: yet it is surprising to see to what a height this symptom will arrive in female habits. An appeal to the ruling tem- perament must therefore always be a safe resource to the physician. On the same principles, I have just dismissed, cured, a case of epilepsy, in a youth of six- teen, an apprentice in this town, which threatened to be permanent. He had no fit after he began his medi- cines. But in order to make great changes in his modes of living, I ordered him to the country, with many alterations in diet, 8cc, during the treatment. 328 4 leptick paroxysms, are convulsions tha/ some- times give alarm of their approach ; but at other times their attack is instant. We cer- tainly possess no medicine that either prevents or shortens these convulsions. I have seen epilepsy checked by the ligature round the thigh, when the sense of the aura, as it is called, was ascending the thigh : but in other cases the ligature did not check the aura, or prevent the fit. The only treatment which 1 can recommend here is the whole rules of pre- vention ; which improve the health, by abridg- ing the predisposition. If as I contend, epi- lepsy is the offspring of the nervous tempe- rament, the force of that must be lessened ; and all cures of this convulsion by any particu- lar article, can have no real existence. Acidity and flatulence being two of the most painful symptoms attending these disea- ses, the common correctors are well known ; they ought to be obviated as much as possible by diet, which has been sufficiently explained. The aerated soda water has now become a fashionable morning draught for the cure of acidity, after a debauch of wine. It is really to be met with in coffee-houses, as if it had ne- 329 . ver been manufactured by the apothecary, and it is humiliating to the physical vigour of Bri- tons to see such degeneracy ; a medicine con- verted into a tavern beverage ! But it is worth mentioning, that a long use of this water hurts the stomach and kidneys, and produces very serious cutaneous diseases, so as to in- jure the skin. I must beg leave to caution persons subject to nervous and stomach complaints, about re- pelling eruptions on the skin, especially of the face, by any severe means. These cutaneous affections are commonly associated with the dyspeptick disposition, and when imprudently forced from the surface, never fail to aggra- vate the internal disorder. The best way is to leave them to the general treatment. It is true, they are particularly disagreeable to wo- men ; but as they are a part of the original malady, so they usually yield with it. Of this patients should be duly warned ; for many constitutions have been ruined by the use of those articles vended under the specious names of creams, dews, honeys, &c. all of which con- tain mercury, lead, or some powerful astrin- gent, that repel the pimples at an improper pe- 2 D 2 330 riod. When stomach complaints have been rendered more severe by this cause, the first and best relief is to recal them to the skin. The warm bath, particularly of salt or sulphur water, is one of the most effectual means. But some medicines of the sudorifick class, such as camphor and ammonia, joined to bark and iron, with warmer clothing, and exercise continued to the sweating stage, will also have considerable effect in restoring the eruption. Morning sickness and vertigo are common with some of these patients. They are felt immediately on standing erect, and sometimes bring on latching and faintness. These symp- toms are chiefly to be imputed to the empty state of the stomach from long fasting. They are best relieved by some tasty food, such as cold ham, cold tongue, &c. taken before get- ting up. But warm tinctures and medicines of any sort ought never to be resorted to. By .way of preventing this sickness, I commonly direct a small supper of meat at going to bed, so as to amuse digestion, and breakfast imme- diately on rising. In the early months of pregnancy, morning sickness is a troublesome attendant: but as the cause cannot be correc- 331 ted immediately the only alleviation is watch- ing the state of the stomach and bowels. Want of sleep, or wakefulness, is one of the most distressing companions of nervous affec- tions : indeed some persons appear scarcely to sleep at all. Cold ablution of the whole body a little before, or immediately on going to bed, is one of the best means which I know, to pro- cure refreshing sleep in these situations. Some people find great advantage from what has been called the air-bath ; that is to get out of bed, and walk to and fro in the room, quite naked, for ten or fifteen minutes. After growing warm in bed, drowsiness and sleep soon succeed this kind of noct-ambulation. But sufficient bodily exercise, with moderate mental recreation, is certainly the most saluta- ry and natural mode of inducing sound repose. I think opium can scarcely be admitted here. The general warm bath, semicupium, and pe- diluvium, may also be tried. The external applications which are em- ployed in cramps and pains, consist of blis- ters ; camphorated oil; ammoniated oil ; vit- riolick aether; saponaceous liniment; mus- tard flour ; warm flannels ; bottles and blad- 332 ders of warm water ; hot bricks ; friction ; dry cupping, &c. The last remedy is often found useful, where there is much pain, with coldness of the part ; as by favouring the in- flux of blood, and thereby exciting heat, it proves stimulant. With the same intention, electricity is often employed to advantage j and to this we may now add galvanism. The warm bath may also be considered a valuable remedy in local pain, and may be practised with the restrictions formerly delivered. The vapour bath, in effect, comes near the nature of the warm bath : but pediluvium being easier accomplished, generally supercedes both the others. The strangury, and other complaints of the urinary passages, are best relieved by the fixed alkalies, ammonia, aether, and camphor, exhibited in aq. menth. pip. with the milder bitters and large dilution. These symptoms are apt to accompany excessive acidity and flatulence of the first passages. I have known cases of this kind becoming truly alarming, from the great delicacy of the patient. This symptom is peculiarly frequent with women subject to the hysterick affection : active exer- 333 cise in the open air is the best preventative. I know not if mucilage can have any effect here beyond dilution from the water taken with it, but even that may be useful. It remains for me to consider the treatment of the bowels, so generally slow in persons of the nervous temperament. To preserve the alvine discharge regular, is an indispensable part of our office. The stomach and bowels being the chief seat of nervous and bilious com- plaints, much of the inconvenience and pain occasioned by constipation is to be referred to their weakened state ; joined to the scanty or vitiated bile which is sent from the liver, as that organ partakes by association and sympa- thy with the intestinal tube. By an inversion of the action of the muscular fibres, the peris- taltick motion is interrupted ; is torpid in one place, and increased in another; which irre- gularity compresses the flatulence into particu- lar portions of the canal ; creates distention, uneasiness, and pain ; and very frequently gives the evacuation much difference in form, consistence, and colour. These appearances sometimes impress the patients and nurses with extraordinary dread and apprehension of * 334 the disordered state of the bowels. While the nervous power of the intestines thus acts tu« multuously, and in insulated portions, violent constrictions are apt to happen, which give birth to the symptoms of colick : and at other times the mind is more particularly alienated, and what is called hypochondriacism and va- pours, are the consequence. It is devoutly to be wished that the bowels could be kept in due action, by diet and exer- cise, without the aid of medicine : but so ma- ny causes conspire to defeat this purpose, that nothing is so difficult to be accomplished. Such patients have generally long accustomed themselves to some purgative medicine, often one of the most improper kind ; and it is not easy to convince them they have been doing wrong. Among these habitual purges, calo- mel and aloes are the most frequent in use. As these articles, as well as all other cathar- ticks, are not directed against the radical cause of the evil, they can be considered only as gi- ving temporary relief. But mercury in any form cannot be long used by persons of weak viscera without harm : and aloes is a medicine of the drastick kind, that produces great irrita- 335 tion in the Tectum, tenesmus, and is apt to bring on procedentia ani, piles and fistulous sores. But purgatives of every description, when frequently resorted to, exhaust the sto- mach and bowels, and never fail in adding to the cause of the complaint. It must therefore be a great misfortune where the body is never moved without the aid of medicine. Such a habit as this ought to be early guarded against, where the dispositicn to cos- tiveness is hereditary. This can be done only by a strict attention to that regimen, which is enforced in the former part of this work. Parents alone can effect this. It must be grate- ful to every medical attendant of a family, where it is known that a predisposition to these diseases prevails, to remind the father and mother of the necessary rules of prevention. Such an r.ffue will reflect great honour on the professional character, as it will prove an ho- nest disregard of emolument, when the wel- fare of their friends, and society itself, is so deeply concerned. Where medicines are re- quired daily for children, in the state of slow bowels, the prospect in advanced age must be dreadful. 336 The diet in the constipated state of body, ought to consist of a large proportion of-fluid aliment; in severe cases it ought to be entire- ly of this kind, with vegetables easy of solu- tion. What solid butcher-meat is taken, must be masticated slowly before swallowed, which will prombte the flow of saliva, assist its com- minution in the stomach, and facilitate its pas- sage onwards. I am well aware that very great obstacles will be opposed to these precepts : some will speak of their dislike to broths ; others that soup disagrees with them; some will be afraid of borborrigmi, and others of their shape. But for the two la3t objections, exercise, not physick, is a certain cure; and with respect to the two former, if health is of so little moment that no pleasure is to be sa- crificed for it, things must remain as they are. The quantity of bread to be eaten must be very small; no pudding where flour forms a part, can be admitted ; custards and such like are allowed : all pastry is excluded ; and all the legumina, such as peas and beans, are forbid. These restrictions are directed because what- ever increases the bulk of the fcecal macs, im- poses a heavier load on the peristaltick motion 337 of the intestines; and consequently a slower action. Where fruit agrees it may be indulged ad libitum. All vinous and spiritous liquors are to be given up, in conditions of torpid bowels : they all act by exciting the absor- bents in the stomach and intestines; and thus deprive the refuse of chylification of that fluid ■ that makes it pass equally and easily along. We ought to begin with the milder laxa- tives first, and so ascend to the more active ; to reap full advantage they must also be often changed. The gentlest are manna ; tamarind infusion ; electuary of senna ; senna; rhubarb ; tartarised kali ; jalap ; aloes ; scammony; jalap and one tenth of calomel; scammony and one tenth of calomel, &c. It is sometimes observed, that nervous and bilious people grow corpulent and full ; this is generally owing to rich food and indolence j and it is a bad trait of the temperament. Such persons however never bear bleeding well, even under some apparently inflammatory dis- position. The best plan here, is to reduce the body by low living and exercise, if these can be accomplished. But nervous persons are the most intractable of all good livers, and have less resolution to abridge their enjoy. 338 mcnts. They not only indulge in large quan* tity, but that is commonly seasoned to the highest degree of stimulus. For my own part I would sooner encounter the prejudices of ahy sick man, rather than those of a nervous glutton. Every surfeit brings additional trou- ble to the physician ; and he will often hear the appetite complained of, where a single dinner ought to have made three. Nothing stands more in the way of a regular medical discipline than errours of this kind, and it is necessary to observe a sharp sighted jealousy over them. When, as has often happened, I have been consult- ed for cases, that seemed beyond the reach of medical assistance, I have seen great advantage obtained by directing the treatment solely against the nervous pre- disposition. This has frequently happened in those desperate afflictions, the cancerous uterus and mamma ; and I have sometimes thought, had the rules of prac- tice been tried sooner, even in such situations, a cure might have been effected. A perfect knowledge of the temperament, in my opinion, forms the only basis for a successful treatment of all nervous and bilious diseases so called ; it leads us to the fountain head ; unfolds the source whence the evils flow, and puts us in possession. of the only means for prevention and cure. FIMS. CONTENTS. PAGE. DEDICATION,.....iii INTRODUCTION, xi I. Chap. The health o* the savage state com- pared with modern times, 15 II. The medical description of the inhabitants of a large town or city ; being an analysis of society, ------ 34 III. Remote causes of nervous diseases, - - 50 IV. Influence of these diseases on the character of nations, and on domestick happiness, 144 V. History and progress of these diseases, 169 VI. The general doctrine of these diseases, 199 VII. Prevention and treatment of nervous diseases, 236 SALEM, N. Y. PRINTED BY J. P. REYNOLDS^ VvZ TtStv c1 * * ARMY * * MEDICAL LIBRARY Cleveland Branch 'AAA.. V, K vy-,, (t..