iU^SSVH apmjumvkjp m^smmm. tytftu rmwriwuri t Ml '^^yy^^W V^V^^v^^^^^v ^VOWWij 1 ' - vVv ■s.V*- :^v^w^^ w*wjjw VWJW^ WMtoA wWV^WvVl iJwMte^mw ^VSiSm y^w^';" *»tf 6«« vv-yv". WjMwy. ,Wy« I 4 S3 i rT^ ^ -i ^ ^^ ^5 M ^3 a., cA h seik H < at 6im c «, / f Some a ;* cor x T Of what is faid of , Innoculating or Tranfplanting' THE Small Pox. By the Learned Dr. Emanuel Timonius, AND v Jacobus Py/arums. With fome Remarks thereon. To which are added, A Few QLxrier. in Aoriffeet .to Uie Scruple? of man/ abotn thubrfofufitefs (fthis'Mctpod PuMifhed ' ■: By Dr. Zabdiel Boylston. B 0 ST 0 X : Sold W S. Gerris#, at his Shop in Can-Hill. 1721. Some Account of Inoculating or Tranfplanting the Small ) Tox; And of the "Benefit and Safety of the Pra&ice. THE Publick having bee 1 lately enter- rained with a very dark and partial Account of this Aew Method of receiving the Swa/I Pox-, and this Account being given as is pretended, from the very Letters of Dr. Timon'tus ai.d Pylirinus ; it is thought rea- fonable and fitting to lay before the Publick this following A'jjlrrt of what thofe Learned Gentlemen have Did of this Practice. But becaufe the (jcntleman who only hath thefe Letters by him, refufes • to lend them ; the Account he* foiuwing is chiefly taken from a known Letter written by a Learned Gentleman of Bcflon to the Woithy Phyficians of the Town. A Faithful ilbridg- ment of Two Ac- counts in the Pbitofo- phical Tfi x 1. /^\HR firft "1 1 from l?r. %njjj) V^-^ Renowned Fellow oftfceT|S$£*r Society ar Lq/idion, (well known, to fonife?| #j/fr*, who alfo attualty knew" the Trutfi^|| die* matter ofFatt now going 4?be related,;* Who writes from Codfyiunqpie in December 171?. And he informs to this ffTe&v ThA •practice of procuring the Smd/lPox by a foi£ Of Inoculation, has be"en introduced OTibng if the ConftantjnopQ&aSshy the Ginfijjtatfs, tnd * Georgians, £nd or/her Afiatkks for db^t Fatty [1 Years. At the rirft the People were cautiptlis and afraid \ but; th* Happy S&ceft on T&w* jWx of Perfons for Eight Yeats now put !t as aw /> */# 17/ aUfufpithn\ Tile Operation *■■ A . ' " **' --- TTJ has Been performed on Perfons of all Aj ioth Sexes, differing Temperaments, & ev. ■:. in the worftConltitution of theAlr* and^c^ that have ufed it ei er died of theSmallPox,t\i& at the fame time, it were fo malignant, that .at' leaft half the People died, that, were infected fl/vith it in the Common way. They that hweth'islnoculationrjrattifedon' them(he faysjare fubjeft unto verySlight Sympr toms,zx& hardly ffimnble ofanySicknefs,nor.Co what Small Pox they have, ever leave any Sca'rs or Pits behind them. They make choice of as Healthy a Yourg Perfon as they can find, that has the SmU Pox of the ibeft fort upon him,on the Twelfth Or ThirteenthDayvof his Decum&ture. frith' 3 Needle they prick 3[bme of the largfcr i'afiules, and, prefs out the Matter comic* i-om them into fome convenient VefTel of 31afs (orthelike) to receive it, which ought firft of all to be walTied very clean with warp Water. A convenient quantity of this Mat- ter being thus colUcledj is to be ftopd clofc, and>feept warm in the*bofom of the" Perfon' that carries it (who ought rather to be fom^ mber Perfon, than what vifited the SicK Chamber for .it, left the Infection of the Small Pox be convey d in the Garment, as iveil as in the £W//*,;and the intended Ope- tatien be. liutt by the. Infeftion being rlrtt con- ' - yeyecl veyed another way, and fo it ihould be con: yeyed as loon as may be to the Perfon that is'waiting to be the Patient. The Patient being in a warm Chamber, is;; to havefeveral fmall Wounds made with a Surgeon's Three edged Needle, or with a Lancet, in.two or more Places of the Skin (the belt Places are in the Mufcles of the; Arm) till fome drops of Bioo$ follow; And immediately let there be dropt out a drop of the Matter in the Glafs * on each of the Places ; and mix'd well with the Blood that. is iTuinsout. The-Wound fhoujd be covered with half a Walnut fhell, or'any fuch con- cave VeiTel, and bound over that the matter may not be rub'd off.by the Garments lor a few Hours \ And now let the Patient (having Fillets on tlae Wounds,).keep Houfe^ahd keep warm,and be careful of his Diet; The Cultdm at Conftantinople is fo'abftairi fromTlefhand Broth for Twenty Days ojt: more. They chufe to perform the Operation either in the beginning of Winter or Spring. The SmairPox begins fooner in fome than others, and with lefler Symptoms in fome than others -, but with happy Succefs in all. Commonly Ten or TwentyPuflules break out; here and there One has no more than two or three 5 Few have a Hundred. There are •fpme, in whom no Puftttles rife, but in the A 2 Places fr ■ • y * Places where the Incifion was made : And here the Tubercles will be purulent: Yet even Tbefehwe never had the SmallPox afterwards, tho' they have Cohabited with Perfons hav- ing of it. Nofmall Quantity of Matter will run for feverai Days from the Places of the lnfcifioit. The Pocks arifing from this Opera- tion are-dried up in a fhort time \ and fall ©£ "partly in f%in Skins,and partly vanifhing by an infenfible wafting. The Matter is hardly fo thick a Pus as m the common Small Pox, but a thinner kindr 6f Sanies, whence it rarely Pitts, except at theflace of the Infcifion.where thedcrtncetl are never worn out, and where the matter isj jrmre of the common fort. If an Apoftem fhould break out in anj (Which is more frequent in Infants) yet therl is no fear, for 'tis heal'd fafely by Suj ~ tion. They fcarce ever ufe the matter of tin Infcitious Small Pox to ferve the Defigns oj a new Infcition. The I/7^»/icion,\ and yet that there fhould be any Truth in the Reports of People's dying under the Ope- ration, or being liable ro the Small Pox after it ? Had Peoples Limbs p"- ifhed, or had they been liable to the Small Pox after it, we may be lute, a few Examples would have put an .end to the Praclice Forty Tears ago. Good Readers, Judge calmly, and like reafonable Men. IV. The Author of thefe Abridgments ad- drefs'd them unto thofe, who had the Av^i* nals in their Ha«ds , and therefore it cannon- be thought, that it was not as Faithful a Re-.' port as he could make of the matter •, But rt having been infinuated, that there might bojj a more full and perfeft Relation, The Author defires it, and I defire it my felf, That the Accountsgiveninthe Philofophical Tran fatl'tomM be permitted by rhe Owner ro come abroadH and be publifji d Word for Word, that imparl tial Men may fee with their own Eyes, the I . true ftate of the Cafe. A V. Ir might be eaiy for me to makeAnfwerM to the Scurrilous things lately Publifhed 2r\ jgainft me, and fatisfy the Publick of the I Faljhood and BafenrJSin them. But I think] it rather becomes a confiderate Man to de-tl cline feolijh Contentions -, efpecially at a time,] when theje is a grievous Calamity upon us, \ (»; that calls us (inftead of railing at one ano- ther; to Unite in Prayers to Almighty GOD, for His Mercies to us. And therefore if any think to go on with their Calumnies fS Foole- ries, I (hail not think fit to take any Notice of them. What I cro (I hope as it has hi- therto done,) will vindicate it felf with Peo- ple of Thought and Probity. VI. I have made my Experiments with alt the Difadvantages tha^t can beimjgined, on 0 J. and Toung, on Strong and Weak, on Male and Female, on White and Black, and in the worftSeafon of the Year ; and on greater 'Numbers', than I'judge proper (confidering the unaccounrable Rage of unadvifed People,) to mention; But more than twice Seven, I can afTure you -, and it has fucceeded well m all, even beyond Expectation. VII. We are yet but Learners -, and hope through Experience to grow more expert in our Practice. In fome of my Experiments hitherto, I have found the Fever iomewhat more intenfe for a few Hours before the £- ruption, and the Number of the Puflles to be iomewhat more than iifual in the Levant. Whether this be from the Seafon of the Tear, or our Different Climate, or our high way of Living, or our want of more Experience I cannot fay, till I fee further. But Experi- ence declares things to fail out for the main, B 2 juft Juft as * the Renowned Timonius ani Pyl a R i n us have related. And I have hitherto by the Blefling of GOD been able with eafe to manage what Fever my Patients have had, and have never done any thing, but what every body knows is done in other Qorqmoia Fevers. Upon the fir ft Eruption this Fever abates and. goes off, the Patients groifl fo eafy, that one has much ado to keep them in the condition of Patients. They have not the leaft Touch of that Second Fever, which People generally dye of in the com- mon way. The Puftules are very few in'*ome$ in others, they are two or tthree Hundred tut at the worft, nothing to what is ufual Sh < the ordinary way of , Infeltion. They quickly dry away. The Patients are abroad again, fooner than they who are infected \v( the common way 5 and they are on all ac- counts as well as they were before. The Sores of tjhe Incifiqn ctigeft and heaik 33 well as any other common Sores do, and if they ihould grow angry ot trouble- fome, a very little Skill and Medicine will ferve to cure them. From all I have hither- to ieen, there can be no more ill eonfequenc^ ot them, thanfrom a fore Finger neglettedi . We are informed that there? is now and ' then, but very rarely, a little Abfcefs in fomeV £mun&ory of the Body : but we have met* With no fuch thing in our Practice, and we (in think when fuch did, or may happen, that it was, or may be from neglec't,or want of Skill in the Practitioner: nor have "our Patients hitherto had the Boils or other Swellings which are common in the ordinary Small Pox, fb much lefs is the Blood and other Jui- ces corrupt in this, than the ordinary way. Now to form a Cry ot "the Plague on This occafion, as if the Pra&i e would bring the Plague : This is fb excefiively ridicu'lous,that it is a wonder any People can think, much lefs, talk fa Are there not a Thoufand People in Town and Country, that have had fuch Swellingsvand Sores as Timonius and Pylarinus mention, that come from Colds, ill Habits of Body, or other caufes as well as from the Plague ? And was it ever known that the Plague was produc'd in this way of Practice > They that have hitherto been under the Operation among us, agree in de- claring, that they have fuffered in a manner nothing -, and that they would rather under*- go it Several times, than fo much as once undergo the Small Pox as 'tis generally fuft fered in the common-way ; tho' they fhould be fure of fufviving it. And fome of them (who are very religious People) have publifh'd to the World, their Thanks to Almighty GOD, fgr fhewing them this way to efcape peath and Mifery. Indeed for any thing ( »4) that yet appears, here is a D'fcoverv, that is a great Bleffing to Mankind, a;d fhould be thankfully receiv'd: A way to doreod our felves againff a dreadful and a deadly Dif- eife, by over ruling the way of it's coming at us, when we fee 'tis coming. Many Lives might be fayed, fome Time alfo, and lome Charge, (which fome it may be,confider) and the Health of the Town much fooner reftored ; if the Pfa&itioners and the People in the Town would come more into this Practice. The other Clamours and Bugbears having been conquered, all that now remains is this:» The People will have the Small Pox again. The only Anfwer that need be given is this; we Jrave never yet credibly hear! any Injian'ce | thereof. And thofe, who have paiTed under ' the Inoculation or Tran {plantation, are every Day vifiting, and attending the Sick , with all the a{Turanee and fafety that can be. So,me will confidently affirm, that to their Knowledge a Man may have the Small Pox a SecondTime in rhe common way. And yet this binders not theEncouragement of rhem who have had it once to be no more afraid of ' catching it. The Cafe f Confcience-diftreffes many wor- thy Good People. The Cafeinfhort we take to be this. 'Almighty GOD in His great'^ ' Mercy to Mankind, has taught us a Remedy^* * to be u'fed when the dangers of the Small I (■'>) *. Pcj. d'itrefs us j upon the ufe of Which '■'Medicate, they fhall in an ordinary way be « fure not to have it loieverely as in the other « way, and confequently not to be in fuch ' « danger ffom this dreadful Diftemper, and * alio to be delivered from the terrible Cir- « cumflances which many of them who reco- « ver of the Diftemper do fuffer for it. Whether a Chriftian may not employ this Medicine (let the matter of it be what it will) and humbly give Thanks to God. for Hxsgood Providence in difcoveringof it to a miferable World;and humbly look up to HisGoodPro- vidence(as wedoin the ufe of any otherMedi- cinejfor thefuccdfs of it ? It may feem ft range, that any wife Chriftian cannot anfwer- it. And how ftrangely do Men that call them- felves hhyfieians betray their Anatomy, and their Philofophy, as well as their Divinity in their invectives againft this Practice ? For in the Firft place, they make a. mighty buftle about AMignant Filth infus'd into the Mafs ot Blood, &c. as if there were no Difference between injecting a quantity of fome poifo- nous Matter in fome large Blood Vcffel, and that of applying a Drop outwardly to the Scarified Skin, which when we confider ap- pears to he only a drop of that which our Skins are fill'd with when we are full of the Small Pcrx, and a confiderable part of which ( 16) is returned into the Blood again, and yet the Sick does very well. And further, when this Drop is apply'd to a Perfon who has had the Small Pox before, and altho' it enters and is receiv'd by Nature in fueh, as well as others, as I have experienC'd, yet nature is able to caft it off without thePhyficiana-help- and that agrees with what our Author Tim- nius tells us •, that when it has been try'd on fuch as have had it before, it has had no effect. Secondly, And as to their Philofcphti that the People will hive it again, this is X wonder to me ; when I fee the Fever produc'f as is necefTary to feperate and caft out the Pocky matter, and that they have a fait ~ Pockot Puftule, and this capable of Infecting i and producing the Small Pox in the ordinatjB way on others, and to the fame Degree, thfl renders-it with me beyond all doubt, that they who have had it once thus in this waj$ are as well fecHr'd from having it again, as thofe who have had it favourably in the other way, which hath been prov'd by thofe that have had but one or two Puftules. Con- ftant Experience has alfo confirmed it in ma- ny thoufands of Inftances. But what make! this Practice fo valuable ro us, in my Opinio? is, that we fhall efcape the Violence, ,Rag$ and Hazard that we are expos'd to in - cowmen way •, except we are infected bef ( 17 ) as we are certain poor Mrs. Efther Webb was, . ------And even there we may hope that the Sores of the Infcifions may help to carry off the Morbifick matter,and faVe the Patient; for this Perfon is recovered, altho' fhe had one Of the worlt Sort that ever was known. And much more on this Head might be faid, why this way of Infetticn is more fafe and eafy, than that of the Common way, but this may fuffice for the prefent. And as to the Divinity, they would limit God in His Blefiing of fome one or other particular part, or particle of His lower Creation, us'd by the Phyfician or. Surgeon to prevent, moderate, alter, or cureaDileafe in their Patient; the which I never yet heard was denied the Phyfician or Surgeon to ufe as aforeiaid by God or Man. But for this I refer my fetf* to the fol- lowing Quarries. N.B. As to the fpiteful and fcurrilous things written againft me and this Practice, at prefent I fhall take no further No- tice of them, but remind the Writers of the ill natur'd Dog in the Fable, that would neither eat the Oats himfelf, nor let the Horfe eat them : So neither will thefe ufe a true and certain way to fave the Peoples Lives, nor are they willing to let any one elfe .ufe it to fave them. I ( i*> A Few Quaeries humbly Offered. -I.TF it fhould be fo that the Companion of GOD to His Creatures,fhould Enlighten us with the Knowledge of a Sweat or z. Purge,' v that would Certainly, or but Probably fecure; us from ever taking the Small Pox, I Enquire^ Whether any People would be fo very foolifh, as to judge it Unlawful to take fuch a Remedy. Or, would not every Wife Man think, that all the Days of a whole Year,wett too few to be turn'd into Days of Thanksgh^\ ing, for the Difcovery of fuch a Bleiling to a Miferable World > Let the matter of the Sweat or Purge be what they will ; 'Tis all one for that. Suppofe it the Powder of. Toads, or the Powder that Johannes Anglicu^ cured Agues with •, or let it be a Succus Va™ rtolatus \ 3Tis all one for that! i II. Phyficians have very often given their Patients a Salivation, to remove, yea, an& fometimes to Prevent grievous Difeafes* Thoufands have Died in and from that 0- peration ; yet becaufe Thoufands have got- Good by it, the Operation is every Day re- peated. There is no body fo Impertinent as to call this, & Tempting of Providence. I Enquire, Why a Dejpumation, or, An Opera- tion that will, we mutt not fay, Salivate, but we. may fay, Dejfrumate, the matter that wouldq ( 19) would be fuel for the Small Pox, at proper , Orifices, can be more liable to Exceptions ; Efpecially, when it was never yet known, that One Perfon has died under it or by it ? Or, why may not the Succus Vanolatus be ufed, as well as Mercury ? III. It is Objected, That you Prefume upon Providence in this Eflay for the Prevention of the Small Pox ; for you don't know whe- ther you fhall ever have the Smallpox, or no. I Anfwer, Bat what if it be as likely that I fhall have it, as it is that my Houfe will take Fire, when my Neighbours an Inch and half off, is in Flames. Pray, fit fill* my Neighbour, your Houfe n not yet en lire : The Almighty can preferve it. But I Enquire, " whether this Objection will not lie againft all the Preventive Phyfick in the World ? I don't Infallibly know, .that I fhall ever fuffer the Difeafe I am going to prevent. IV. The Obje£tion here is, / make my ' felf Sick, when I am Well. But I again fay, Will anyMan decry all Preventing Phyfick,zs- Unlawful > Why do our Phyficians encou- rage People every Spring and Fall to take it > Don't People take the Poifon of a Vomit into their very Stomachs, to prevent a Sicknefs a I thoufand times lefs to be feared, than the Small Vox ? Why may not I as well take a [ Poi/M into my Arm, or my Leg, to prevent f 20 ; fuch a Malady. Many have Died of a Vomit, It is not yet known, that any one ever Died of the Operation, that is now fo cavil'd at. To fay that our SAVIOUR'S words, The whole need not a Phyfician, forbid all preventing^ Phyfick, is a grofs abufe of them. Beiides, I am not whole, while I have the Fuel of the Small Pox lodging in me. V. Meerly to prevent a little Headaeh,ot fome fuch Height Malady, may not I apply fuch a Poifon, as an Epifpajiic of Spamfh Flies to my Arm; A Poifon which will let the Hu- mours of my Body all a working, and pene- trate unto the very Bladder,and produce even a Bloody Urine there ? VI. But an Anxious Fear of the SmaH& Pox ; is not this an Evil Difeafe ? Efpeci-'T ally when I have it fo near me,that 'tis nexr$ to a'Miracle if. I efcape it > If I take Phy-\ fick only to Remove and Prevent this Fear,' it can't be faid, that / make my felf SickS*, before I have any Difeafe. VII. The Celebrated Sydenham advifes, That Purges be ufed, before? the Infection of the Small Pox be taken,, which hopefully prepare the Body, to feel fewer of the Small Pox, and of the better fort, -, Will any be fo Ridiculous as to count this Unlawful, under a frivilous pretence, that they do/Ct know whether they fhall have the Small Pox or no. VIII. I humbly Enquire, whether the Sixth Commandment has not required us to uie cleans that may be Lawfully ufed for th Prefervation ojour ownLivestS* others ? And what is thereUtfta/»/in whatisnowpropofed? IX. There is a filly Cavil -, We pray that ti>e Small Pox may not Jpread-, and yet we do our fives by Tranjplantation fpread it. But I Enquire whether People know what they Pray for ? Our Prayers are that a Dangerous and Deftrullive Small Pox may not Spread, We do not Pray, that the ufe of an Effetfual meatns to fave our Lives from the Danger of Dejlru^ion by the Small Pox, may not be Revealed, Practiced & Profpered. /X. It is Cavilled (for to fay ,0bjetted, would ne too eafy a word for fuch Impertinence,) \'hat this New Way comes to us from the feathen, and we Chriftian! muft* not Learn \e Wiiy of the Heathen. 1 Enquire, Whether ,ui Hippocrates were not an Heathen ? And whether our Galen were not an Heathen? And. whether we have not our Mithradate from ^it^he Heathen ? And whether the firft Inventer of our Treacle were not Nero's Phyfician ? And whether we have not learnt fome of our very Good Medicines from our Indians > But this New Way has been ufed by many Thou- fir :1s of Chriftians ; And it is from Chrifiians ve have the Communications* of this New Way which we moft rely upon. But are there •v"^e who pals for Courant-Chriftians. that e worfe than Infidels? And,Gentlemen-Smffe- e*s,I pray,whom, £jj ,Vfm!parr t0 Smoke of ? XI. If it fhould be (6, that a Defpumami: ♦of the Blood made by applying the Succua Variolatus, would (by the Bleffing of GQl'< generally fave the Lives of them that tome under it, I Enquire, What they will hai e^tt Anfwerfor, that by their Menaces and Out- rages put a ftop to fuch a General bcndi* And I Enquire whether aPhyfician,who m.ik. * the-Experiment upon Himfelf, that fo n njy Thoufands of precious Lives may (if it %• ceed well; be brought into a likely wa nf heing preferved, & prolonged, fhall def^v. to be treated as a Murderer', or not ra^r " iSeemed a General Benefattor. • XH. Were not the Phxfvmnsa Great Bd»- of them, upjjn. Arms, ag,nntt the ufe of x\l: s Cold harlr&tyjt tffiCe jc hatred a* a;'. Vjt< ty of:Difeafes, and fayed 'ffioufands of Li;r has not the ufe of it now ob'ained,w&i/Jb*> t<>; $ill:orno? And now they alforecommend .r. When the ufe of the /^///j &7r£ was fi it introduced, was there not as loud a Cry a- gainft it, as can be imagined ? Yea, D© pot many to this Day mine themfelves by the ufe ot it, with an indifcreet and prepofterous ma- nagement > But fince Hundreds of thoufands- of Lives have been faved by it, are not th?y generally counted very odd phyficians, who dc not.ufe k, as often as they have oceafion ! I Enquire, whether any fort of Pratticr-,"' th#Whole Art ofPhyfick ever came tons wi a^trongerRecommendatioii than this ofIncc .• latio-i or Tranfplanution. F I N i L' H^dL. Hid. UlZ £70 I7JLI tyfirw^t ^A .;^^y*'v; .C/Vivi WMf^ ^ *w*w"* V-\ . V, ,v »,!«» Vv^^vccc^y ffW- «»1^VV v ^ 5 ' v. /fc«^U^vu i^M1 M^w^. WHJctfyrV y^bv'?vv: :^;Vu,yv^ V v\;vv >v ^ WytfV ^-■Vvjui w* :-.'.f.^-vj "f.vtj^f :r ^ - '■■^W'VV'v'^^y'JL/b^K VUUUv lA;vWvY ^wwyuwWi;Vvw^u w^ „.^y^y.w^»^%i /juy^uuVyoUAH^^^^^'J