'/^■DZQZQZQZ£Z£ZCZQZQuQZ®ZQl.>-CaGZiG&C^(JQ(JQCZC:Q.OQJ(Jr^ FAMILY PHYSICIAN. JEWETT'S FAMILY PHYSICIAN THE lATROLEPTIC PRACTICE OF MEDICINE, CURING OF DISEASES PRINCIPALLY BY EXTERNAL APPLICATION AND FRICTION. BY MOSES JEWETT. ^ Gen/'; „ PUBLISHED BY THE AUTHOR 1838. Entered according to Act of Congress, in the Year 1838, By Moses Jewett, In the Clerk's Office of the District Court of Ohio. COLUMBUS: SCOTT AND GALLAGHER, PRINTERS. No. 42, State-Street. CONTENTS. Pkeface, --......V Introduction,......--vii PART I. DISEASE AND ITS TREATMENT. CHAP. I. Our Remedies. Stimulating Liniment, - - - - - - 19 Liniment for Fevers and Fever and Ague, - - - 23 Liniment for Nervous Affections, 25 Liniment for Cholera Morbus,.....27 Liniment for Coughs and Consumptions, - - 29 Liniment for Rheumatism, - - - - - 31 Liniment for Head-Ache, - - - - *, - 33 Laxative Liniment,.......34 Vegetable Cerate,......35 Pile Salve,........35 Tetter Salve,..... 36 Venereal Ointment, - -.....36 Itch Ointment, ..-----38 Health Restorative, or Vegetable Syrup, - - - 39 Diaphoretic Drops,......40 Pectoral Tincture,.......41 Female Drops,.......41 Alterative Drops,.......42 Essence of Life,.......42 Nerve Sanative,......- 43 Brown Wash,.....- - 44 Lotion for Dyspepsia, - - - - - - 44 Cancer Preparations, -.....45 A CONTENTS. CHAP. II. Fever,.........47 Treatment,.......- 57 Yellow Fever,........60 Treatment, ------- -65 Treatment with our Remedies, ... - 69 Spotted Fever,........72 Treatment,.......78 Scarlet Fever,........83 Treatment,.......83 Cholera,.........83 Symptoms of Cholera in India, - - - - 85 Character of the epidemic in Sunderland, - 92 1. Symptoms of the Incipient Stage, - - - 93 2. Symptoms of the Cold, or Choleric Stage, - - 94 3. Symptoms of the Febrile Stage, ... 95 4. Prognosis, -------97 5. Diagnosis, ------- 98 6. Appearances presented on Dissection, 99 7. Nature of the Disease,.....101 8. Proportionate Mortality, - - - - - 104 Treatment, 1. Of the Incipient Stages, - - - 105 2. Of the Cold or Choleric Stage, - - - 106 3. Of the Excited or Febrile Stage, - - 109 As to the Proximate Cause, or Pathological Inception of Cholera,.......Ill Treatment with our Remedies, - - - - 111 Plague,..........113 Treatment,.......117 Ague,..........120 Treatment,.......121 CHAP. III. Phthisis, or Pulmonary Consumption, - - -, 123 Treatment,........128 Cough,.........131 Treatment,........134 CONTENTS. Rheumatism,........134 Treatment,........136 CHAP. IV. Dyspepsia,........139 Treatment,........150 Mental Derangement,......151 Treatment,........156 Hypochondriasis,.......157 Treatment,........159 Hysterics, - - - - • - - - 160 Treatment,........161 Depressed State of the Mind,.....162 Treatment,........163 CHAP. V. Diarrhea, or Looseness,......165 Treatment,........166 Cholera Morbus,.......167 Treatment,........168 Colic,.........169 Treatment,.......- 170 Dysentery,........171 Treatment,........172 CHAP. VI. Stone, or Calculus,.......175 Lithiasis—Gravel and Stone,.....177 CHAP. VII. Hemoptysis, or Spitting of Blood, ... - 181 Treatment,........I83 Hemorrhage,........183 Treatment,........I84 Hematuria, or Voiding of Blood by Urine, - - 184 Treatment,........i85 Hemorrhoids, or Piles,......I86 Treatment, - - ■ -. - - - " 187 CONTENTS. CHAP. VIII. Quinsy,.........l8^ Treatment,........191 Catarrh, - .......191 Treatment,........I92 Hooping Cough,.......193 Treatment, - - - - - - - -194 Rubeola, or Measles,.......194 Treatment,........197 Parotitis, or Mumps,......198 Treatment,........200 Croup,........■ 200 Treatment,........202 Enteritis,......- - - 203 Treatment,........204 Erysipelas, -------- 204 Treatment,........205 Chilblains,........205 Treatment,........206 Hysteritis, an Inflammation of the Womb, - - 206 Treatment,........208 Leucorrhea, -------- 209 Treatment,........210 Prolapsus Uteri,.......211 Treatment,........212 Asthma, -........212 Treatment,........213 Sick Head-Ache,.......214 Treatment, -------- 214 CHAP. IX. Scrofula, or King's Evil,......217 Treatment,........219 Scurvy,.....• 221 Treatment,.....- - - 222 Syphilis,...... - 223 Treatment,........225 CONTENTS. Herpes, or Tetter,.......226 Treatment,........228 Tinea Capitis, or Scald-Head,.....228 Treatment,......-- 229 CHAP. X. White Swelling,.......231 Treatment,........233 Whitloe,.........235 Treatment,........235 Hernia,.........236 Treatment,........237 Polypus,.........238 Treatment,........238 Dropsy, --------- 239 Treatment,........242 CHAP. XI. Angina Pectoris,.......245 Treatment,........247 Obstructed Menstruation, - - - - - - 248 Treatment,........248 Mortification,........249 Treatment,........251 Atrophy,.........251 Treatment,........252 Leprosy,......""" 2^3 Treatment,........254 Diabetes, - .....255 Treatment,........256 CHAP. XII. Congestion, - - - - - - - - 257 Treatment, -------- 258 Icterus, or Jaundice,.......259 Treatment,........260 Nervous Diseases,.......261 Treatment,........262 CONTENTS. Tic Doloureux,.......2^2 Treatment,........263 CHAP. XIII. Cretinism—Swelled Neck—Bronchocele, - - - 265 Treatment,........2@7 Phlegmasia Dolens—Swelled Leg, - - - - 267 Treatment,........271 Hydrocephalus, -------- 272 Treatment, -------- 275 CHAP. XIV. Hydrophobia,........277 Treatment,........281 Sick Stomach, or Milk Sickness, ... - 282 Treatment,........283 Influenza,........284 Treatment,........284 Fits. 1. Apoplectic,.......285 Treatment,......- - 285 2. Epileptic,.......286 Treatment,........286 3. Hysteric,.......286 Treatment, - - -.....287 PART II. TESTIMONIAL. Testimonials, - - - - 189 to 381 PART III. PHYSIOLOGICAL. Mechanism of the Human Skeleton, - - 383 Heart,......- 394 Lungs, .----- 396 Breath, ------- 399 Head, ------ 399 CONTENTS. Brain, - Nerves, - Ear, ... The Appendages of the Human Eye, Muscle, - Cartilage, ... Bone, --.. Spine, Joint, - Chyme, ... Liver, - Bile, Blood, .... Kidney, Spleen, - Intestine, Diaphragm, - Pelvis, ... Uterus, - - - Embryo, ... Ovary, - 401 403 405 407 410 414 415 416 420 421 422 423 424 428 429 429 431 432 432 434 434 Chimistry, PART IV. MISCELLANEOUS. CHAP. I. 435 CHAP. II. Acids, Alkalies, Albumen, Benzoin, Caustic Potassa, - Caustics, Essential Oils, Decomposition, Chimical, 445 446 447 448 449 449 450 451 CONTENTS. CHAP. 111. Origin and Regulation of Animal Heat, - Dr. Arnott's Hydrostatic Bed for Invalids, Hunger, - - - - - Aliment, - - - - Diet, - - - - - Digestion, - CHAP. IV. Respiration, Perspiration, Secretion, Sympathy, Crisis, Somnambulism, Injections, Pregnancy, CHAP. V. Irritability, - Clinical Medicine, - - - Contagion, - Antidotes, - Animal and Vegetable Nutrition, Saline Bath, - - - - - Application of Galvanism to Poisoned Wounds, Granulation, - - - - - Hereditary disease, History of the Small Pox, Anatomy, The Pulse, - - - - - Life of Man, - Antiaris, - Glossary, - Index, - 453 456 461 463 466 466 469 470 472 472 473 474 475 476 479 482 485 487 493 494 495 496 496 498 502 503 504 506 509 529 PREFACE. The interest which has been excited, and which is steadily progressing among many men and gen- tlemen of science in the United States, in relation to our concentrated remedies for the removal of disease, and the anxious solicitation of our friends for a work devoted to the latroleptic practice of medicine, have induced us to publish this volume. The favorable reception which has attended our articles, heretofore published, particularly those up- on the subject of cutaneous absorption, has induced us to believe that the same candor will be extended to this work, and that a desire to do good to the afflicted will induce medical gentlemen of science to continue to us that aid and patronage, which it is our pleasure to acknowledge has been so liberally extended. Although the plan of the work, as well as the mode of overcoming disease, is entirely new, we feel confident it will be acceptable to gentlemen of science and sound learning. It was our original design to introduce, as an ap- pendix, a synopsis of Anatomy and Physiology, but on reviewing the most valuable works on those branches of science, we were satisfied that justice VI PREFACE. could not be done them, without swelling this vol- ume to a size beyond our present purposes. We have therefore contented ourselves, by publishing a number of important articles on those subjects in the Miscellaneous department of the work. The Pathology, Prognosis and treatment of vari- ous forms of disease, are the most important parts of the whole. Much care has been taken to render these arti- cles interesting, and easy to be understood—and as the modes of treatment have been derived from long and successful application in the hands of men of discriminating minds, we are warranted in assuring the public that confidence may be placed in them. INTRODUCTION. In the following work, the Pathology and Prognosis of disease will be treated agreeably to the best received opinions of the most learned physicians of the present age, and we shall state some of the principles by which we are governed in adopting a new mode of treating disease; and which, though received and believed to be correct in theory by some, provided agents could be found to effect the object desired, has by others been doubted for want of facts so established and developed as to sustain the principles referred to. Our grand object will be to simplify the practice of medicine, and overcome disease with the greatest promptitude and certainty. This, we contend, is accomplished by our discoveries of very many of the agents wisely designed by providence for the re- moval of various diseases, and their application to the system by the latroleptic practice, or the external application of medicine. Our theory, therefore, is respectfully submitted to the learned and to gentlemen of science throughout the world. We do not claim infallibility in that respect, but as to the facts—the effects wrought by such agents as we have thus far externally employ- ed—we challenge a world to disprove them: we do not submit a negative proposition—we have proved them, and by thousands of living witnesses can establish their influence upon the system, as clearly as that jalap and rhubarb operate as cathartics when taken into the stomach. As it regards our theory, we submit the leading facts in favor of cutaneous absorption, without which, (or the aid of nervous sympathy, or some yet unknown principle of Galvanic Electric influence,) our whole theory would fall to the ground, though the facts unexplained would still remain, like the elements, un- changable. VIII INTRODUCTION. We have been accustomed to see the progress of disease slowly arrested by the means generally adopted, and it is not strange that many should doubt whether an improvement upon any new principle in practice, had taken place, so long as we are constantly annoyed by hundreds of nostrum-venders, who profess to cure every disease by one remedy. But in guarding against this class of speculators, the wise and intelligent will not steel their minds against a real improvement, which has been substantiated by the most demonstrable facts, although at the first blush the plan might appear somewhat novel. It is well known, that all medicine taken into the stomach for the removal of disease in some distant part of the body, produces its beneficial effect by a secondary influence upon the diseased organ. If, for instance, a medicine is offered to the stomach for a pain in the head, sufficient time must elapse, be- fore the object can be accomplished, for the medicine to pass the digestive apparatus, and reach the distant organ through the agency of the blood and nerves. Somewhat similar is the pro- cess of curing diarrhea by the employment of cathartics—they stimulate excessively the already irritated and enfeebled intes- tines, and when the cathartic stimulant is exhausted, agreeably to a well known law of the living economy, the intestines are inclined to repose, their capability of being excited is diminish- ed, a langor ensues, and a cure may be the result. Now our ex- ternal remedies when applied to the body are readily absorbed— they shield the skin against the too rapid evolutions of the elec- tric fluid, which is believed to have a powerful influence in con- centrating disease. When the proper remedies are applied to the head in one case, and to the bowels in the other, they are placed in the nearest proximity with the diseased organs, being absorbed, and at once brought into immediate conflict with the malady. Another advantage not hitherto named, is that in obstinate and violent cases, by taking at the same time, internally, an appropriate medicine, the disorder may be attacked on both sur- faces, that, is, externally and internally at the same time. The superior advantages which this mode presents are too obvious to every one, to be insisted on here. Whatever may be said, however, theoretically upon this interesting subject, in the introduction of this work, will be drawn from experience INTRODUCTION. 1% tilone, as theory, without substantiating facts, is seldom produc- tive of any useful end or purpose. If we suppose ourselves divested of all knowledge of remedies suitable for the restoration of health, with disease and death exciting our sympathies, and urging us to the employment of means for the relief of our suffering friends and fellow-beings, we might reasonably expect that, in our attempts to afford relief, we should extend the havoc of death rather than arrest the pro- gress of disease, before a knowledge of the nature and effects of the remedies employed had been obtained. Nothing but expe- rience could remove our embarrassment, and give an assurance, in our efforts to relieve the afflicted, that we were not using an instrument of death, instead of a remedy friendly to health and life. We should be wanting in duty to the public at this time, were we to withhold the numerous facts in our possession, illustrating the applicability of our remedies to most forms of disease, with which our country is afflicted. If we were to contend, however, that one preparation could be so contrived, as to constitute a sovereign remedy for all dis- eases, we should have reason to expect an unfavorable reception among the most discerning; but our plan will be acknowledged to be more rational. We combine, concentrate, and extensively compound, the best therapeutical agents for various forms of disease. This princi- ple has been more rigidly adhered to by us, than by any one who has heretofore prepared medi6ine. For instance—we have a preparation which Will uniformly cure sick headache. We have another, which is equally certain in arresting and curing the rheu- matism. Whenever, as is sometimes the case, the pains of the hip are, by the remedy, transferred to the head, the rheumatic liniment will at once arrest it, but the headache liniment will not; neither will the rheumatic liniment cure the sick headache ■^-showing, in an important light, the principles which we have adopted, in the combination of our remedial agents. On the subject of cutaneous absorption, we would say that it is intimately connected with the latroleptic practice of medicine, or the curing of disease by an external application of remedial agents. As our preparations are becoming more and more ex- tensively known and adopted by medical men in the United 2 X INTRODUCTION*. States, and as much of their general usefulness may depend on a more extensive knowledge of the subject, we will here adduce a few of the reasons which have for a long time been adopted by men of sound science, in favor of the doctrine in question. The function of absorption is one of the most curious and im- portant in the animal economy. The matter of which the living body is composed, is in a state of continual change; old particles are every moment carried out of the system, and new ones are every moment conveyed to the place occupied by the old, and deposited in their room. The constituent matter of the living body is therefore never the same in two successive moments. This change of the constituent matter of the living body is ef- fected by the process termed absorption, and the agents by which this process is carried on, are termed absorbent vessels. The absorbent vessels possess a peculiar structure, essentially different from that of arteries, veins, or any other vessels of the body, and their action likewise is altogether peculiar. The absorbent vessels consist of two distinct sets. The first arise from the alimentary canal, and more especially from the small intestines. They absorb the digested aliment, and are the in- struments by which the new particles of matter which are ne- cessary to supply the loss occassioned by the removal of the old, are carried into the system. The new matter, which is termed chyle, is of a white color, very much resembling milk; and these vessels, when full of it, have the appearance of mi- nute tubes, distended with a milky fluid, hence they are called lacteal vessels, (that is, milk vessels.) The other set arise from every part of the body—from the whole of its external surface __from every one of its tissues—from every one of its organs, so that the point of the finest needle can touch no part of the body, without coming in contact with some part of this system of vessels. At every point of the body these vessels are always at work, taking up new and carrying away the old and worn out particles. But, further, those which are spread out on the external skin, and those which are spread on the internal skin, on the membrane which lines the air passages, for example, and on that which lines the passages of the stomach, are capable of taking up many foreign substances which may come in contact with them, and often powerfully affect the system, by introduc- ing into it these foreign bodies. Whatever may be the nature of INTRODUCTION. XI the substance contained in this second set of vessels, and from whatever source it be derived, it is always without color when pellucid; on this account it is termed lymph—and these vessels are therefore called lymphatics. The lacteals, then, contain new matter derived from the digested aliment. The lymphatics contain the old and worn out particles of the system, together with whatever substances may have been taken into it from the surface of the body. Of the real existence and active operation of the function of absorption, there is indubitable proof. The great number of cases of disease which have recently been successfully treated by external remedial agents, without the exhibition of any me- dicine internally, might be judged by some, as indubitable evi- dence of the truth of the doctine in question. The wasting of the flesh, a dissipation of the solids, a diminution of the weight of the body, under certain circumstances, while the general system remains unaffected, can only be accounted for, on the supposition that processes are continually going on within the body, (not dependent on external influence) which remove from the system both the solid and the fluid parts of which it is composed. The important fact has been fully proven, that various sub- stances, when placed in contact with a living surface, produce the same effect on the system, as when received into the stomach, or injected into the veins. Arsenic, when applied to an external wound, will sometimes affect the system as rapidly, and as pow- erfully, as when taken into the stomach. A strong infusion of tobacco, when applied to the pit of the stomach, will occasion vomiting; when injected into the rectum, will produce almost instant fainting, and unless care be taken, the fainting will pro- duce death. These phenomena can be accounted for, only by supposing that the substances in question are readily conveyed into the system. It being established, that such effects can be produced on the human system by poisons, through the medium of absorption, what may not be expected by a concentration and refining of the most powerful therapeutical agents, adapted to the various forms of disease, when conveyed into the system through the same channel? We have proven, by actual experi- ment, that the remedial agents act as readily on the system in relieving disease, as the poisons do in destroying life. It has XII INTRODUCTION. been proven, by direct experiment, that the human hand is capa- ble of imbibing, in a quarter of an hour, an ounce and a half of warm water, which, for the whole body, is at the rate of six or seven pounds in a single hour. Sailors at sea, in perishing need of water, have been relieved by a shower of rain, which wet their under clothes, and afterwards have sustained life, by wetting their clothes in sea water, which invariably gave relief, the absorbents taking up the particles of water, and rejecting the saline qualities dissolved in it. The functions of absorption explain many phenomena con- nected with health, with disease, and with the action of reme- dies. The agents which produce disease, and especially the widely extended and powerful causes of fever, namely, animal and vegetable substances in a state of decomposition; these, to- gether with the effluvia of marshes, exhalations from the animal body itself, and perhaps other noxious gases diffused in the atmosphere, afford striking illustrations of its operation. An exposure for a few minutes, to an atmosphere loaded with marsh effluvia, of an intensely noxious nature, may produce a protract- ed ague, or even instantaneous death. Even a few inspirations of an atmosphere, rendered foul by the exhalations from the human body, may produce, in a person previously healthy, immediate nausea and vomiting, followed by severe and perni- cious fever. A person laboring under small pox, may contami- nate the room to such a degree, that a healthy person, breathing this air but a short space of time, may become affected with the disease, although the infected may never have come in contact with the infecting person. In all these cases, a poison is dif- fused through the atmosphere, which comes into contact with the surface of the body, and so affects the system through the medium of absorption. The free dilution of this poison with pure air, will destroy or render innoxious these malignant agents; hence, persons who are under the necessity of remain- ing constantly in the chambers of the sick, may remain there with perfect impunity, if these chambers are frequently and thoroughly ventilated; while, if ventilation be neglected or im- perfectly performed, not only is the disease of the patient aggra- vated, and, perhaps, by this course alone rendered mortal, but his nurse is also sure to suffer; hence the value of this further fact, which cannot be too constantly borne in mind, that these INTRODUCTION. XIII noxious agents always affect the system exactly in proportion to its want of energy. Exposure to a powerfully noxious agent, when the stomach is empty, when the body is exhausted by fa- tigue, when the mind is depressed and desponding, will occasion a mortal disease. Exposure to this same agent, when the body is nourished, when the functions are carried on with vigor, when the mind is cheerful and confident, will be attended with no appreciable effect. There is no kind or degree of sickness, with which a family or an individual may be affected, in the management of which, the knowledge of facts of this kind may not afford useful suggestions; but of far more importance are they, when a malignant or mortal epidemic is generally preva- lent. Our remedies are far the most valuable antidotes we have known, in cases where disease has originated from noxious va- pors and an impure atmosphere. The readiness with which they are carried into the system through the medium of absorp- tion, the instantaneous action they impart to the circulating fluids of the body, thereby expelling the impurities of the blood by the perspirable pores, give relief to the patient, and stimulate and guard the system against future attacks. Nor is there less practical utility in attending to the action of absorption, in relation to noxious agents which are generated within the body itself. When secretion is vitiated, and the morbid matter is absorbed by the lymphatics—when digestion is imperfect, and unwholesome chyle is absorbed in the lacteals —when the excretory portion of the alimentary canal is torpid, and the faecal matter which ought to be carried out of the sys- tem, is retained there, and in part absorbed; in such cases, the sensible qualities of the perspiration, the odor of the breath, the foul state of the skin, the loss of strength, the irritable and feverish condition of body and mind, sufficiently declare the disorder of the system. Considerations such as these show the value of pure air, simple and easily digested food, moderate and regular exercise, and medicine termed alterative. By altera- tive remedies, we mean the medicinal substances which are ab- sorbed from the surface of the alimentary canal, and entering the current of circulation, are conveyed by this channel to the secreting organs, and which, by their influence over the actions of these organs, effect a salutary change in the general func- XIV INTRODUCTION. tions of the body. It will not be denied that all the organs of the body are excited to this performance of their functions by certain external agents, which are called stimulants—such as air, water, heat and so on ; of these the most powerful and indis- pensable, in a healthy state, is the aliment. Upon the quantity and quality of the aliment depend the quantity and quality of the blood, and upon the quantity and quality of the blood depends, in a great measure, the energy of all the functions of the organs. But when, by disease, the secretory organs have become weak- ened and languid ; when most of the aliment taken into the sys- tem does but little more than add to the accumulated impuri- ties of the circulating fluid, the digestive powers of the stomach are in a measure destroyed. In this situation, our remedies, composed of stimulants, tonics, and diaphoretics, externally ap- plied, have produced the most sudden relief to the oppressed organs ; the general circulation is promoted ; the collected mass of impurities is thrown off by perspiration, and sometimes by the intestinal canal ; the patient is relieved without the occur- rence of a tedious state of convalescence. Life can be main- tained but a short time under the total privation of food, while the excessive privation of it produces effects on the system which have not been often observed with accuracy, but which are remarkably uniform, and highly curious and instructive. Though we are opposed to abstinence in common cases of dis- ease, yet there are cases wherein it may become necessary, and be obviously capable of becoming a most energetic remedy. When the mass of the fluids and solids of the body are too abundant, abstinence is capable of reducing them to almost any extent that can be required ; and, when a full application of our stimulating liniment is regularly made during such absti- nence, it is unattended with any diminution of strength or injury to the health, but it contributes to the advancement of both. As we have made a partial digression from the subject in question, we shall continue this digression by a few hints on perspiration ; and, as absorption is a function of the skin, the insensible per- spiration is intimately connected with it, and its abundant pro- motion is effected by our remedies. A learned physician says: "The large quantity of insensible perspiration from the lungs and skin, together, amounted to thirty-two grains per minute three ounces and a quarter per hour, or five pounds per day. INTRODUCTION. XV Of this, the cutaneous constituted two-thirds, or sixty ounces, in twenty-four hours. After many experiments, the medium average was found to be eighteen grains per minute, of which eleven were from the skin, making, in twenty-four hours, about thirty-three ounces. Admitting this statement to be, in some degree, imperfect, still enough remains to demonstrate that ex- halation is a very important function of the skin. It is admitted by all that the cutaneous exhalations of the skin are more abun- dant than the united excretion of both the bowels and kidneys; and that, according as the weather becomes colder or warmer, the skin and kidneys alternate in the proportion of the work they perform, most passing off by the skin in warm weather, and by the kidneys in cold. The quantity exhaled increases after meals, during sleep in warm dry weather, and by friction, or whatever stimulates the skin, and diminishes when digestion is impaired, and in a moist atmosphere." Here our external remedies become eminently useful; they stimulate the surface, aid the insensible perspiration, and give strength to the cuta- neous organs. The same writer further remarks,—"that every thing tends to show that perspiration is a direct product of a vital process, and not a mere exudation of watery particles through the pores of the skin." If this be a fact, how important is it to health and life that the functions of the skin should be kept in a healthy state; and how much is gained by an external application of durable stimulants, which, when absorbed, do not vaporize, but remain in the system, shielding it from sudden checks of the insensible perspiration. " People know the fact, and wonder that it is so, that cold ap- plied to them, or continued exposure in a cold day, often pro- duces a bowel complaint, a severe cold in the chest, or inflam- mation of some internal organ; but were they taught, as they ought to be, the internal structure and use of their own bodies, they would rather wonder that it did not always produce one of these effects." The idea of curing diseases by external applications is not exclusively of modern origin. It prevailed in the earliest periods of medicine, and was highly esteemed by the Arabic practition- ers, who "applied to the skin medicine intended to exert its in- fluence upon the bowels as purgatives, on the lungs as expecto- XVI INTRODUCTION. rants, and on the kidneys as diuretics." In later times, this method has been, by several writers, and particularly treated by Dr. Jackson, in a work rich in observation and experiment, writ- ten expressly on the latroleptic method of administering medicine by cutaneous absorption. Indeed the latroleptic method has ever been in practice, more or less, from the very infancy of medical science down through the long and darkened vista of time to the present moment, and has been adopted by every sect and o-rade of practitioners. The matter contained in the small pox virus, if confined for a short time on the arm without a puncture, will as effectually produce the disease as if inserted in a puncture. The pure concentrated Prussic acid applied to the tongue of a dog produces instant death; and a portion of it spread on the arm of a man produces the same effect. Some have carried their opposition to this doctrine so far as to aver that " nothing, whether metallic, mineral, or vegetable, enters the circulation of the human body, unless previously assi- milated,'1'1 that is, changed into the same nature of the body, or, more technically, converted into nutriment. Of such an ob- jector, we would ask if he suppose poisons taken into the stomach to undergo this process? If so, how can they be poisonous? Moreover, substances, in order to become assimilated, must pass the digestive apparatus, a process of several hours, while poison acts instantaneously or in a few minutes. It is also generally ad- mitted that the lacteals, through which the assimilated matter passes into the circulation, absorb nothing but what is con- genial to health and life, in other words, nothing but the chyle. How, then, can the doctrine be sustained, " that nothing enters unless previously assimilated.'''1 The doctrine of venous absorp- tion appears to be well established; and this would be overset if the other were true. We contend that if, through the medium of cutaneous absorption, poison can be administered which will produce disease and death, so likewise, through the same medium, a medicine may be introduced which will restore health and vigor. To the objector against cutaneous absorption, we would propose the following questions: 1. Is the skin possessed of sensibility which makes it suscep- tible to the action of all stimulants? It must be recollected that, in cases of external remedial applications, the nerves of the skin must be first excited—first impressed; they must catch the pe- INTRODUCTION. XVII culiar power of the remedy, and then transmit the impression to its appropriate organs, or the organ whose functions will be principally affected by its influence. 2. If the skin possess so wide a range of sensibility as to render it susceptible to all kinds of stimulants, why should it not take up the stimulating properties of various remedial ar- ticles, when these are applied in a solid form, or in powders? 3. If the doctrine of cutaneous absorption be false, why, or in what manner, does the urine become changed, in color, from the application of various kinds of coloring matter to the skin? Can coloring matter be conveyed through the medium of ner- vous sympathy? 4. If the doctrine be false, how is the sensation of thirst re- lieved by the application of water to the external surface of the body? But, admitting these effects are produced through the medium of nervous sympathy, br from any other cause, the re- putation of our external remedial agents would remain unim- paired, as they stand on their own merits. Their sensible qualities are those of a strong and permanent stimulant; they relieve pain by restoring vital action and a free circulation of the blood to the painful parts; they remove disease by acting in accordance with that theory which makes disease to consist of obstructed circulation and diminished vital energy; they have so far sustained their reputation with every honest, intelligent individual who has become fully acquainted with their therapeutical powers. 3 PAKT I. DISEASE AND ITS TREATMENT. CHAP. I. OUR REMEDIES: CONSISTING OF LINIMENTS, SYRUPS, LOTIONS, CERATES, TETTER SALVE, PILE SALVE, VENEREAL OINTMENT, ITCH OINTMENT, TINCTURES, ETC. The following are the most important articles of our Con- centrated Chemical Compounds, now in extensive use in the United States. A general mode of application, in various forms of disease, is hereunto annexed. We shall treat the subject more elaborately in connection with the Pathology of disease. STIMULATING LINIMENT. This was the first article prepared, and has been attended with the most complete success. It has been constructed on the principle upon which many of our external remedies are based; and though the first, is not the least efficacious, and will bear a comparison with any medicine now in use. It has been found efficacious for any general or local pains in the back, breast or side, pleurisy, cholic, diarrhea; and has also proved successful in curing 20 DISEASE AND ITS TREATMENT. cases of bronchocele, hydrocephalus, local inflammation, morbid affections, incurvation of the spine, paralysis, &c. &c. DIRECTIONS FOR USE. For Slight Pains—rub the part affected with the Lini- ment, with much friction, and apply a plaster spread with the same. Plasters made of glazed cloth are preferable, as they exclude the influences of the external atmosphere, and do not waste the Liniment by absorption, nor soil the clothes. For Severe Pains—in addition to the above, place a warm brick near the part affected, renewing it if necessary. If the pains be very extensive and general, the Liniment should be freely applied to the body and parts affected, and to the soles of the feet; and when in bed, place warm bricks to the feet and sides, and take the Diaphoretic Drops until a free per- spiration is produced; which course may be repeated daily or oftener, according to the violence of the pain. For Weak Joints—rub on the Liniment, with much fric- tion, twice a day. For Bruised Limbs—if the skin be broken, apply the Vegetable Cerate; if not, and inflammation has taken place, apply the Liniment once a day. For JIgue in the Face—apply a plaster of the Liniment on going to bed, and place a warm brick, or a bag of hot hops or meal to the same. A small portion of the Liniment ap- plied to the jaw, inside of the mouth, will be beneficial. For Curved Spine—apply the Liniment twice or three times a day over the whole length of the spine, and a plaster of the same; occasionally, or each night, heat may be applied in either of the ways above directed. Once in three days wash off with warm soap suds, wipe dry, and then make a fresh application of the Liniment. The Vegetable Syrup or Alterative Drops may be taken according to directions. For Lame Back—wear a plaster on the back, and renew once or twice a day; if not relieved, apply heat as above directed, over the region of the pain. For Cholic and Inflammation of the Bowels—apply the OUR REMEDIES. 21 Liniment very freely, with much friction, to the bowels, and a plaster of the same: if not relieved, apply heat as above, and take the Diaphoretic Drops according to directions. For Dropsy—if in the feet and legs, soak the feet in weak lye or warm water, rub them upwards while in the same, wipe dry, and apply the Liniment once or twice a day; and if the feet are much swollen, bandage them, commencing at the toes. If the abdominal region be the seat of disease, apply the Liniment freely over that region, and wear a plas- ter on the same. For Dyspepsia and Liver Complaint—apply the Lini- ment with friction to the stomach, wear a plaster of the same over the region of the liver, renewing it once or twice a day. When there are pains in the shoulders or back, apply the Liniments to those parts on plasters. In severe cases, apply the Liniment once or twice a day on the whole surface of the body, and wear plasters on the parts as directed; once in three days wash off with warm soap suds, then with salt and water, wipe dry, and apply the Liniment. In these com- plaints, if not readily relieved, take the Vegetable Syrup, Alterative Drops, and Essence of Life, according to direc- tions. If any fresh symptoms occur, apply the Liniment to the body as above, and to the soles of the feet, and when in bed, place warm bricks to the sides and soles of the feet; take Dia- phoretic Drops until a perspiration ensues, which will remove these symptoms, and if renewed a few times, will accelerate the cure of all the complaints. An application of the Lini- ment to the stomach, and on plasters worn over the region of the liver, renewed once or twice a day, for a length of time, without any other application, has effectually cured many long standing cases of dyspepsia and liver complaint; when this course does not soon succeed, it will be necessary to per- severe a considerable time in order to become permanently relieved. In extreme cases we have found the application of plasters made of glazed cloth, and spread with the Liniment, covering the whole chest, to be of great advantage. In other 22 DISEASE AND ITS TREATMENT. cases, where the liver has become extremely torpid, and the Liniment did not appear to have much sensible effect, we have applied a bath to good advantage. Take a gill of alcohol, and add as much salt as will dissolve in it, set it on fire, under a chair, on which let the patient sit, covered with a blanket to his neck: this will cause a copious perspiration, without any diminution of strength; after which wash off, and the system will more readily receive the Liniment. In these affections the bowels generally become constipated. The exhibition of our Vegetable Syrup will generally overcome this diffi- culty; but should it not be sufficient, a gentle cathartic may be administered. Note. Where the lungs are in any degree affected, the Consumption Liniment ought to be adopted. For Bronchocele—apply the Liniment two or three times a day over the neck, without a plaster; wear a piece of silk next to the skin and a flannel over it, and take freely of the Vegetable Syrup, or the Alterative Drops. This course per- severed in for two or three months, has uniformly reduced the neck to its proper size. If the Liniment does not appear to cause a sufficient action in the parts affected, apply three or four drops of the Nerve Sanative over the neck, which will aid much in effecting that object. For Hydrocephalus—shave the head and apply the Lini- ment over the whole surface, two or three times a day; take our Alterative Drops according to directions. The Liniments may be applied once a day in small portions in the ears, on the neck, &c, and freely to the bottoms of the feet; the Nerve Sanative may also be applied to the top of the head, three or four drops at a time. We have known a sufficient action o-iven to the system to cure this distressing complaint, in some instances, in a very short time; but if immediate relief be not given, the patient ought not to despair, as we never have had a failure reported to us, even in cases which have been pronounced, by the ablest physicians, beyond the reach of medicine. OUR REMEDIES. 23 LINIMENT FOR FEVERS AND FEVER AND AGUE. This preparation has been particularly adapted to bilious fevers, and fevers generally—combining the best concentrat- ed medical agents for that class of diseases. The results of its use have been of the most satisfactory nature. A suitable application of this Liniment according to directions, with our Diaphoretic Drops to induce a more speedy perspiration, has not failed in any instance yet known, to give a very speedy ease to the patient, reducing the feverish symptoms with great promptness, and in ordinary cases, overcoming the disease in a very short space of time. In cases of great sever- ity, a continuation of the remedy for a few days, has gener- ally produced an entire cure; and in such cases, the patient, instead of being left with a great degree of prostration, and a long and enfeebled state of convalescence in prospect, from the tonic and restorative effects of the Liniment, which braces the system and restores the appetite, produces a speedy and entire recovery of health and strength. In fever and ague, with one or two applications of the Lini- ment before the periodical return of the chill, or at the hight of the paroxysm, we have never known it to fail of prevent- ing a return, and entirely eradicating the disease. Under the head of fevers, we shall have occasion to say more on the subject of this remedy, as we have the evidence from a number of the most scientific physicians of our nation, who have, from practical experience, become acquainted with its efficacy, and do not hesitate to pronounce it to be of as much importance to the human family, as any ever discovered. DIRECTIONS FOR USE. In slight cases of Fever—the application of the Liniment, with warmth and friction, and the patient kept in bed, to promote perspiration, will produce relief in a short time. In such cases, a convenient mode is to apply the Liniment on retiring to bed, which abates the fever, and enables the patient to enjoy a refreshing sleep. 21 DISEASE AND ITS TREATMENT. Iii severe cases of Fever—let the Liniment be applied over the whole surface of the body, and to the soles of the feet, with friction; apply hot bricks to the feet and sides, and once in twenty minutes, give the patient a half tea spoonful of our Diaphoretic Drops, diluted in hot water sweetened, until a profuse perspiration takes place. If the patient be kept in a profuse perspiration for two hours, and the Liniment fully applied to the stomach, the fever will be arrested with- out administering an emetic, or the recurrence of a single paroxysm. In some instances, there will remain for some time, on the surface of the body, much heat, after it may be discovered by the pulse, that the febrile symptoms are re- duced. In many severe cases of fever, it is recommended to soak the feet, and wash the whole surface of the body with warm water, before the first application of the Liniment After the fever has entirely subsided, it may be of advantage to wash the body with warm soap suds, then with salt and water—wipe dry, and apply the Stimulating or Fever Lini- ment once or twice, which will add much to the strength and comfort of the patient. In cases of Fever and Jlgue—when it can be done, let the Fever Liniment be applied, accompanied by the Diapho- retic Drops, in the manner above stated, about half an hour previous to the time of the expected chill, until a profuse perspiration is produced; or, if the chill arrives before the application can be made, then, during the paroxysm of chill or succeeding fever, apply the Fever Liniment in the same manner, which will very generally arrest the disease, and prevent a return of chill or fever; and the patient, by ap- plying the Liniment once or twice a day, for a few days, will be entirely restored to health and strength. The object of the Diaphoretic Drops is to produce, more speedily, a copious perspiration, and to aid in regulating the tone of the stomach; if they should not be at hand, warm herb tea can be substituted, though the drops are more prompt, and have a more extensive and beneficial operation. Many persons, after undergoing a copious perspiration by OUR REMEDIES. 25 means of the Fever Liniment, upon its subsiding, have appre- hensions of taking cold—to prevent which, it is important to make free application of Stimulating or Fever Liniment to the body, as that previously applied, has become absorbed into the system. This course renders the patient less liable to the effects of the atmosphere, and is indispensibly necessary to invigorate by the tonic properties, and overcome the debili- tating and febrile symptoms. This course should be repeated once or twice a day for a while, even if no paroxysm of fever should occur after the attack is arrested. Where these directions have been fully attended to, we have never known an unfavorable result. Scarlet Fever and Measels—are cured by the use of the remedies used for fever, with a readiness seldom produced by any other applications. For Small Pox and Chicken Pox—this Liniment may be used as in cases of other fevers, accompanied with Diapho- retic Drops. They determine the disease to the surface of the body, and uniformly prevent the fatal effects of its strik- ing to the vitals. We have witnessed the most decided advantage by the ap- plication of this Liniment to the surface of the body, in cases of internal as well as external inflammation. It produces action which causes the inflammation to subside, and reduces the inflamed parts to a healthy temperature; and the same Lini- ment, when applied to the extremities, which have become cold, will raise the heat and create a healthy circulation. Note.—In all cases where there is any difficulty in causing awjrofuse perspiration readily, by the usual treatment, we wish to impress the importance of applying the alcoholic vapor bath, as laid down in this work. In extreme cases, the object will be more readily effected by first applying the Lini- ment over the whole surface of the body. LINIMENT FOR NERVOUS AFFECTIONS. This article comprises some of the most valuable medicinal agents for quieting, composing, and restoring the nerves to a 4 26 DISEASE AND ITS TREATMENT. healthy action; and its success has been very great in cases of long standing nervous irritation, and in cases of convulsive fits; and will generally succeed in hysteria, epilepsy, and St. Vitus' dance. It has entire reference to diseases depending upon the derangement of the nerves, and competent to afford great and permanent relief. In a complication of disorders, where the nervous system is affected, it is recommended to be used in connection with another Liniment adapted to the case of the patient. In the testimony of cures, parallel cases have been given, of using two Liniments on different parts of the body at the same time with success. DIRECTIONS FOR USE. Apply the Liniment to the neck, breast, the whole length of the spine, and the inside of the arms, thighs, and legs, once or twice a day, until relief is obtained. Sometimes the Lini- ment has been applied to the crown of the head, and spread on plasters, to the bottoms of the feet, to good advantage. Also, take a tea-spoonful of our Vegetable Syrup three times a day. When the Vegetable Syrup cannot be obtained, take our Al- terative Drops according to directions. For Asthma—apply the Liniment to the throat and neck generally, and on plasters, to the breast and between the shoulders; at the same time, take two or three times a day our Pectoral Tincture, and in severe cases sufficient of them to produce slight vomiting—also bathe the feet in warm water, dry them, and apply the Liniment to the soles of the feet, and when in bed, place a warm brick to them. The Nerve Sanative and Essence of Life are used to good advantageyin this complaint. For Mental Derangement—shave the hair from the head, apply the Liniment three times a day over the head, neck, and breast, and the whole length of the spine, and apply our Stimulating Liniment to the breast, bowels, and bottoms of the feet; take the Vegetable Syrup according to directions, or if not to be obtained, take the Pectoral Tincture in small doses of four to six drops, three times a day for one week, OUR REMEDIES. 27 and then increase so as to cause vomiting. Apply the saline bath twice a week, which is made by adding about three quarts of salt to twelve pailsful of water, made as warm as can be borne; in which bathe the patient fifteen minutes, wipe dry, and apply the Liniment. The Liniment should be ap- plied in the ears twice a day, and once a day a small portion in the nostrils. The Nerve Sanative must be applied to the top of the head, and the whole length of the spine, in small portions. The Essence of Life may be taken, mixed with the Vegetable Syrup, three times a day. This Liniment is used to advantage, when the patient's nervous system has become so deranged, as to be unable to bear more powerful treatment. Females, affected with nervous and uterine affections, will find this Liniment beneficial. Sometimes, in chronic complaints, where the nerves are very irritable, we find it advantageous to apply this Liniment - generally to the body, until relief is obtained, and then make use of the Stimulating Liniment. As the nerves are the seat of a great number of the most afflicting diseases, it is important that every aid should be put in requisition for their relief. We venture to say that no remedies possess more power than our Nerve Sanative and Essence of Life; but as they are articles which have not long been before the public, we shall notice them fully in the course of this work. LINIMENT FOR CHOLERA MORBUS Is offered as a valuable remedy for cholera morbus, cholera infantum, diarrhea, cholic, and all bowel complaints. The speedy effect it has in giving relief, more so, it is believed, than by any remedies internally administered—the ease of its application, particularly in the cases of children, who so often suffer from these complaints, presenting such obstacles to the administration of nauseous remedies—together with the benefit of having a remedy always ready for use—are 2S DISEASE AND ITS TREATMENT. advantages of great importance, and highly useful to persons and families when traveling. DIRECTIONS FOR USE. In cases of Cholera Morbus—apply the Liniment to the stomach, bowels, and bottoms of the feet, and also apply hot bricks to the sides and feet in severe cases. Use freely of our Diaphoretic Drops, until perspiration takes place. This Lini- ment alone has cured an immense number of cases of cholera infantum, without any other remedies, and the ease of its ap- plication to children renders it extremely useful. In common Diarrhea—relief can be obtained generally in a few hours, by rubbing the stomach and bowels with the Liniment, and wearing a plaster of the same on the stomach. In cases of Bilious Cholic, and Spasmodic Affections of the Stomach and Bowels—this Liniment may be applied to good advantage. Where the pains or cramps are severe, apply the Liniment freely to the region of the pain, placing a warm brick to the same, which facilitates the absorption of the Liniment; take freely of the Pectoral Tincture in prefer- ence to Diaphoretic Drops, as they will cause speedy relief, by producing immediate and easy vomiting, without cramping the stomach. When relief is obtained by these remedies, the bowels generally become regular without any recourse to physic. In Dysentery and cases of Hemorrhage—apply the Lini- ment to the stomach, bowels, and at the termination of the spine; take the Drops as before directed, and apply hot cloths to the bowels, and a hot brick to the feet. In addition to this, let the patient drink freely of warm tea made of smartweed sweetened, with a little milk added. We speak with confidence of the valuable properties of these remedies. Were it in our power, we would not rest until the hundreds of thousands of mothers in the United States, who yearly mourn the loss of children, should be made fully acquainted with the fact, that relief has uniformly been OUR REMEDIES. 29 obtained by these remedies, where they have been properly exhibited. LINIMENT FOR COUGHS AND CONSUMPTIONS, Has proved, for the disease for which it is adopted, a most valuable remedy, as will readily be observed by adverting to the cases reported. It has relieved the most distressing coughs, lingering cases of consumption, and diseases of the lungs. It operates by arresting the decay of the lungs, re- leasing the corrupted matter, and causing it to be discharged by the mouth or intestinal canal, and proves healing to the lungs. At the same time, highly useful tonics and puri- fiers of the blood, are introduced into the system, by means of the Liniment, and the use of our Vegetable Syrup, which is intended to be used in connection with it, as a most valua- ble and important addition. Cases of the most alarming na- ture, and of many years suffering, have been, by a regular use of these remedies, entirely relieved, and permanetly cured, as can be proved by the most undoubted testimony. In whooping cough, the Liniment and Syrup have pro- duced immediate relief, and effected speedy cures. In com- mon colds or slight coughs, relief can generally be obtained by the use ofJthe Liniment alone. DIRECTIONS FOR USE. In cases where the Lungs are inflamed only—and the patient has not for a great length of time been subject to a cough—relief may be granted by applying our Cough Lini- ment to the side, and between the shoulders, two or three times a day; at the same time taking the Vegetable Syrup, or if that be not at hand, take from four to twelve drops of the Pectoral Tincture, three times a day, and at night apply plas- ters spread with the Liniment, and a warm brick to the bot- tom of the feet, and take some warm herb tea to cause free perspiration; at the same time, Tonic Bitters may be taken two or three times a day, to sustain the strength of the pa- tient. In more advanced stages, where the patient shall have 30 *" DISEASE AND ITS TREATMENT. been afflicted with a slight cough a long time, pains in the breast, sides and shoulder-blades, hemiplegia, and emaciation, with evident symptoms of the lungs having become ulcerated, a more elaborate course ought to be pursued—the Liniment should be worn on plasters, applied to the breast, back, and on the bottom of the feet, renewed twice a day. If the sys- tem has become very impure, this will cause small pustules to appear on the surface in two or three days, which will dis- charge virulent pus. The parts should be washed with warm castile soap suds at each dressing; and once in two or three days, the patient should be washed entire in warm soap suds, then in salt and water, make free use of the flesh brush, and apply the Liniment again. The Liniment should also be rubbed over the whole body, particularly the throat and spine. If the pustules become too sore for the Liniment to be borne on them, the Vegetable Create may be applied for a few dress- ings, and then, the Liniment resumed. The Cough Syrup should be taken three times a day, in tea or table-spoonful doses, as the tickling sensation attending the cough may de- mand. The Pectoral Tincture must also be administered in doses of from three to twelve drops as occasion may require. This article is one of the best expectorants known; and when taken in large doses, excites nausea and vomiting, but we seldom find it necessary to produce this effect. If the patient has chronic wandering pains, an under dress of white silk is valuable to be worn. The diet should be light, exercise mo- derate, night and damp air avoided, and the feet kept warm. In cases of ulceration, this course will generally cause a dis- charge of matter in two or three days, sometimes by vomit- ing, and at other times, by the intestinal canal. If port wine be agreeble to the patient, it may be taken in small quantities. We have known some instances of sudden relief by the course here recommended. In such cases, it will be absolute- ly necessary for the patient to follow up the remedies, or at least apply the Liniment for a considerable length of time to confirm the cure. But if, through the agency of external remedies, the morbific matter can be expelled from the sys- OUR REMEDIES. 31 tern, the digestive organs restored to a healthy tone, and the whole functions of the body strengthened, there is much gained towards the restoration of health. These effects, it has appeared, we have been enabled to produce, principally, by our remedies externally applied; for by the use of the Liniment on the stomach and bowels, we have frequently known a healthy state of both to take place, though not always without the aid of some medicine taken into the stomach. To aid in the relief of the cough, we sometimes prepare a syrup in the following manner: take two pounds of turnips, and skin them one third of an inch thick; two pounds of loaf sugar pulverized: place a layer of the turnips in a bake-oven, and so on alternately—then cover it tight, and place it over a slow fire, for three hours—then strain it and bottle it for use. Dose—one table spoonful three times a day. Covering the chest with a jacket of glazed cloth, spread with the Liniment, as recommended in some other cases, has effected a cure in many instances when all other means had failed. It has been with much diffidence that we have published some of the results of experiments made with our remedies, in cases of consumption. We never have spoken confidently in this matter, until we had treated a large number of cases, which had been given up by all orders of physicians as incura- ble. These favorable results, together with the testimonials from almost every section of the United States, vouched by physicians, clergymen, and gentlemen of undoubted veracity, have induced us to publish the most successful practice by which patients, laboring under pulmonary complaints, have been relieved. LINIMENT FOR RHEUMATISM, For inflammatory rheumatism, sciatic affections, common rheumatism, local pains, and affections of the gout, is recom- mended with confidence for these excruciating complaints, as a remedy possessing more power to relieve, and to perform a more radical cure, than has been generally accomplished by any other means. 32 DISEASE AND ITS TREATMENT. DIRECTIONS FOR USE. For Inflammatory Rheumatism—apply the Liniment once a day over the whole body, with friction—keep warm, and make free use of our Diaphoretic Drops. When the pain is deeply seated, a plaster spread with the Liniment must be worn over the part, and a bag of hot hops or meal, or a hot brick applied thereto. If relief is not directly obtained by these means, apply the Liniment more frequently. For the Gout—if in the feet or legs, soak them in weak lye, wipe dry and apply the Liniment freely, wrap in flannel, and when in bed, place warm bricks to them, renewing them as they get cool. Take the Vegetable Syrup and Diaphoretic Drops according to directions. If the joints be swollen, plasters of the same Liniment must be worn over the region of the affected parts, renewed once or twice a day; and if the parts are painful, a bag of warm oats or hops ought to be ap- plied over the plaster. If the case be of long standing, the Vegetable Syrup and Diaphoretic Drops may be given com- bined together, and as a change, the Diaphoretic Drops may be occasionally omitted, and the Alterative Drops or Nerve Sanative may be adopted. Sometimes we have known these preparations to be continued a number of days without an apparent beneficial effect, and afterwards the patient, by per- severance, has been cured by them. The Nerve Sanative, taken in small doses of two drops, and applied outwardly on the affected limb, has proven an excellent auxiliary in the gout. After heating up the affected limbs for a number of days, if the heat become severe, we cool the parts by an application of the Vegetable Cerate, for a day or two, which will also allay the pain, but there is nothing equal to the Nerve Sanative in extreme cases. A sweat may be administered by the use of alchohol and salt, as heretofore directed, occasionally to good advantage. If in the Breast—apply the Liniment to the breast freely; take Vegetable Syrup and Pectoral Tincture. If in the Head—make similar applications to the head, OUR REMEDIES. 33 neck, and spine, and use the Syrup and Pectoral Tincture. In paroxysms of fever, or in extreme cases, if perspiration is not produced speedily, the patient should be rubbed with the Fever Liniment, apply hot bricks, take Diaphoretic Drops, and plentifully of hot herb tea, until a free, copious perspira- tion is produced. In either of the above cases, much benefit would be derived by an occasional use of the saline bath, which is made by about three quarts of salt, to twelve pailsful of water, made as warm as can be borne, in which bathe the the patient fifteen minutes, wipe dry, and make an application of the Liniment. N. B. In very severe cases of rheumatism, when the sys- tem is generally affected, if relief is not obtained by the means directed, the patient is advised to adopt the same course as is recommended in extreme cases of the gout. For Numb Palsy—the Liniment may be applied three or four times a day over the affected parts, and once in four days steam those parts in bitter herbs, wash off, wipe dry, and then apply the Liniment, and take freely of our Diaphoretic Drops. This course, persevered in, has cured cases of very long standing. An occasional use of the saline bath would be advantageous. If the disease be of long standing, and the system be deranged, the patient will find much advantage, after the first application of the Liniment, in taking an enietic of our Pectoral Tincture, and perhaps it may be necessary to repeat it two or three times. LINIMENT FOR HEADACHE, Is competent to relieve, immediately, the most severe cases of headache with a single application, and in a short time to effect an entire cure of long standing sick headache—a disease of the most distressing nature, suffered by numberless persons for years, without more than temporary relief, and often diffi- cult to obtain that result. It is positively known that a fair trial of the Liniment will effect a radical cure. 5 34 DISEASE AND ITS TREATMENT. DIRECTIONS FOR USE. Apply the Liniment freely, with much friction, over the forehead, crown of the head, back of the neck, spine, and the breast. For Sick Headache—in ordinary cases, apply as above, wrap a silk handkerchief round the head, and apply plasters, with a hot brick, to the feet. In more severe cases of long standing, make the above application daily, and wear a small plaster on the back of the neck, and sometimes a small quan- tity of the Liniment, inserted in each nostril and the ears, which, though for a few minutes, will be pungent, will give immediate relief. If the stomach be foul, take ten or twenty drops of our Pectoral Tincture, or a sufficient quantity to cause a gentle vomiting, which will be effected with these drops, without the least danger of cramping the stomach, and relief will be immediately gained. We have seldom witnessed cases so severe as to render all these applications necessary. We have the evidence in a number of instances, where immediate and permanent relief has been given in cases of chronic sick headache, by the ap- plication of the Liniment alone. LAXATIVE LINIMENT. This Liniment is competent to effect a passage of the bow- els, which have for a long time been constipated, and where the patient is much emaciated, and a cathartic is indicated, this method of procuring a passage is peculiarly advantageous, as the object is effected without weakening the patient. DIRECTIONS FOR USE. Apply the Liniment to the stomach and abdominal region freely, and also on the small of the back and bottom of the feet, and place warm cloths to the bowels, and hot bricks to the feet. Sometimes a passage is effected by these means in a few minutes, without the recurrence of pain. OUR REMEDIES. 35 VEGETABLE CERATE, For burns, ulcers, wounds, salt rheum, scald head, chapped hand, and almost every eruption that appears on the skin. DIRECTIONS FOR USE. For Burns, Cuts, and Ulcerations—it should be used by spreading on very thin leather. These plasters should not be removed under thirty-six or forty-eight hours. In Scald Head—the hair should be closely shaved, and every day the sore surface thoroughly cleansed with hard soap and warm water. The Cerate should be applied over the affected part three times a day, liberally, covered with thin muslin or netting, to prevent the annoyance of flies; any other covering appears to keep the sores too warm. Con- tinue this course ten or twelve days; then have recourse to our Tetter Salve, and continue the use of it in the same way, until a cure is accomplished. When the general health appears to be affected, or the cure progresses slowly, rubbing the whole body every second or third night with our Stimulating Liniment, being first cleans- ed in soap and water, will greatly expedite a cure. To cleanse the system, the patient may take our Alterative Drops, as directed. Many astonishing effects have been produced, in cases of broken bones, with the Cerate. In small fractures, let the limb be bound up, covered with the Cerate, after the bones have been adjusted, and remain two or three days without dressing, which will much accelerate a cure. PILE SALVE. A variety of cases of piles, even of the most obstinate character, of many years' standing, have been effectually cured by this application. DIRECTIONS FOR USE. Rub the Salve freely about and up the anus daily, and in 36 DISEASE AND ITS TREATMENT. extreme cases, several times in twenty-four hours, inserting as far up as can be reached; at the same time, take two or three times a day of Stoughton's Bitters, or any other suitable tonic. In severe cases, our Stimulating Liniment may be used by rubbing it on the bowels and back, and spread on plasters' worn on the same places, which will have a tendency to regulate the stomach and the bowels, by which the cure will be accelerated. The Pile Salve, alone, is competent to effect a cure in most cases. TETTER SALVE. This Salve is particularly designed for the cure of tetters and ringworms, and to succeed the use of our Vegetable Cerate, in the cure of scald head. DIRECTIONS FOR USE. For Tetters, Ringworms, fyc—apply the Salve, by rub- bing the parts affected once a day, or oftener, cleansing with soap and water daily. For Chapped Hands—2, little rubbed upon the same for two or three nights successively, will seldom fail of curing. A single application will, in slight cases, entirely relieve, and the parts assume a healthy appearance by the return of the ensuing morning. VENEREAL OINTMENT. DIRECTIONS FOR USE. Apply the Venereal Ointment two or three times a day on the affected parts; at the same time rub the whole surface of the body with our Stimulating Liniment, with the excep- tion of the parts above named. Drink freely of a tea made one-fourth of sassafras, and three-fourths of sarsaparilla, or if that cannot be obtained, substitute burdock root. Keep the bowels open with a gentle physic, and occasionally take a few drops of balsam copaiva, dropped on sugar. OUR REMEDIES. 37 Note.—Though many confirmed cases of venereal have been relieved by the above prescription, we intended them more particularly for common cases of gonorrhea, in which, generally, the patient may procure the medicine and cure himself. But in advanced stages of the disease, and particu- larly syphilis, the following directions will be found import- ant. If the patient be afflicted with ulcers, let them be wash- ed with castile soap suds daily, and then apply the Brown Wash; after which, apply the Venereal Ointment, until the venereal virus is entirely eradicated, when the sores may be cured by applying plasters spread with Cerate, and renewed daily. At the same time of these applications, let the patient take half a wine glass of the Vegetable Syrup four times a day, and drink freely of sarsaparilla tea. The Syrup is far preferable to any preparation heretofore known, in cleansing the blood from the venereal taint; and although an immediate effect will not be discoverable, yet when persevered in, it will restore the system to health. It may be necessary to use the Syrup five or six weeks in very obstinate cases. The above contains the most sure, prompt, and efficacious course of treatment for this disease. Some of the most loath- some cases have been cured by it. The course we recommend can be understood and adopted by the patient himself, without exposing his situation to the physician. Thousands of young men have suffered this dis- ease to run on until their constitutions were destroyed, from fear of making their situation known. If the patient shall entirely abstain from ardent spirits, and persevere in the above course, however bad his case may be, we do not hesitate to warrant a cure. When chancres appear, which will be known by the little eruptions, scabs, and ulcers, arising on different parts of the head of the penis, accompanied, at first, by itching, and gradu- ally changing into pain, we would recommend the use of the Brown Wash, and the Venereal Ointment applied to the af- fected parts, taking a table-spoonful of the Vegetable Syrup, four times a day, and keeping the bowels gently open. 38 DISEASE AND ITS TREATMENT. When the disease has run on for a length of time, so as that the absorbents have taken up the venereal poison, the gland- ular system will be affected—usually the inguinal glands, or the groin. These glands will become swelled and inflamed. Pain in the groin, and some degree of hardness. These are indications of bubo, and can be checked and much relieved by wearing a plaster of Stimulating Liniment over the region of the pain, renewed two or three times a day. Should a rupture or a scirrous affection be mistaken for a bubo, still the above course will give relief. In all cases of swelled testicles, or extreme glandular swell- ing in the region of the groin, a poultice made of boiled white beans, beat fine, with an equal portion of slippery elm bark, is an excellent remedy. In some extreme cases of syphilis, we have prepared a Liniment to be applied over the whole of the body, which is composed of concentrated agents, calculated to aid in cleans- ing the system from the disease. Sometimes it has been ad- vantageously applied on the sound surface of the body, when the ulcers have been treated with Venereal Ointment, poul- tices, etc. It has been fully demonstrated that this disease is not entirely confined to the dissolute. Instances are known where the venereal taint has been inherited from ancestors: others, where it has been caused by fortuitous circumstances. In fact, we hazard nothing in saying it may be communicated by inoculation, in the same manner as the small pox, and per- haps by inoculating for the small pox, with matter taken from the pustule of a man who is infected with venereal. ITCH OINTMENT. The variety of preparations which have been invented for this loathsome disease, and to be sold in almost every drug shop in the country, would seem to be sufficient; and espe- cially so, as many of those compounds have a deservedly high reputation. Nothing could have induced us to have brought this preparation before the public, but the fact of having ef- fectually cured a number of obstinate cases of six or seven OUR REMEDIES. 39 years' standing, where every other prescription had entirely failed. We have learned the fact, that this preparation has been efficacious in a number of eruptive cases, which had been unyielding to the usual forms of treatment. DIRECTIONS FOR USE. Rub the Liniment upon all the parts affected, particularly round the wrists, under the arms, upon the elbows, inside and out, under the hams, and round the ankles. All the eruptions of the body, caused by the disease, should be rubbed with the Ointment. HEALTH RESTORATIVE, OR VEGETABLE SYRUP. We do not hesitate to aver, that this Syrup, so far as we are acquainted with its effects upon the human system, espe- cially when accompanied with the application of our Stimu- lating Liniment, far exceeds any other preparation that we have any knowledge of. If there be any chance for the re- covery of patients in chronic complaints, or if the disease be within the control of medicine, with proper agents accompany- ing it, this Syrup will prove effectual. It may, in some cases, be necessary to give it for a length of time, before its salutary effect will become manifest; though in all cases we have wit- nessed, there remained no doubt on the mind of its superior efficacy, after one or two days' use. The astonishing effect which is produced on canker in the throat and mouth, and in cases of women who nurse their children, which are sometimes incurable by any remedies heretofore discovered, (unless the child be weaned,) is alone sufficient to recommend its adoption. In cases of bleeding at the lungs, consumption, liver com- plaint, nervous affections, asthma, cutaneous eruptions, white swellings, scrofula, syphilis, diseases occasioned by the use of mercury, general debility, and most of the chronic complaints of females, we hesitate not to recommend this Syrup as inval- uable. In what manner it acts upon the system is of but little con- 40 DISEASE AND ITS TREATMENT. sequence to know, if we are enabled to testify of its good effects. It is pretty evident that it must change the secre- tions, expel the morbid matter by the skin, kidneys, bowels, or intestines, although it has but very little sensible effect upon any of those organs. The composition of this article is essentially botanical, and highly concentrated. Some of its ingredients have heretofore been used as a medicine only by the red men of the West. DIRECTIONS FOR USE. In ordinary cases—a dose for an adult is a table-spoonful, and for a child a tea-spoonful, three times a day. DIAPHORETIC DROPS, For promoting perspiration in cases where that end is desired, which they will be found to produce in a short time. DIRECTIONS FOR USE. In cases of Fever, Fever and Ague, Scarlet Fever, Bil- ious Cholic, Cholera Morbus, Rheumatism, Numb Palsy, Liver Complaint, and in all cases where the system has become morbid—(in which they operate as a powerful expec- torant and diaphoretic, and should never be omitted in con- junction with our Liniment for Fevers)—to be taken in half tea-spoonful doses, for adults; for children, half that quantity, diluted in hot water, well sweetened, once in twenty minutes, until a free perspiration takes place. When the stomach is very foul, they will sometimes cause vomiting. In cases of Colds—the Drops are used to advantage, when our other remedies are not at hand. The Drops may be taken as above, and applied externally about the neck and stomach; soak the feet in warm water, wipe dry, and when in bed place a warm brick to the same, and take freely of pennyroyal, or any sweating herb tea, which will, in many cases, arrest a cold without any other medicine. OUR REMEDIES. 41 PECTORAL TINCTURE, A valuable expectorant, and highly useful, with other rem- edies, in removing diseases of the lungs. This Tincture is one of the most ready, safe, and efficacious emetics in the whole Materia Medica, and may be resorted to with great advantage where this remedy is indicated. It warms up and stimulates the stomach, and causes vomiting without the least danger of cramps during the operation. DIRECTIONS FOR USE. In Coughs and Colds—this preparation is administered in doses of from three to ten drops, three or four times a day, for adults, and for children in proportion. In cases of Bilious Affections—twenty drops taken, will generally produce gentle vomiting and cleanse the stomach. In all cases where it is important to promote expectoration, a resort to this remedy will produce the desired effect. The dose of twenty drops is competent to produce vomiting when the stomach is very foul, but in urgent cases when it becomes necessary to cause immediate vomiting, we sometimes give the Tincture in tea-spoonful doses, once in five minutes, dilu- ted in warm water, until the effect be produced. FEMALE DROPS. These Drops are intended to correct profuse, or restore obstructed, periodical discharges, peculiar to females, (a due regulation of which, is so essential to their health,) and are of the greatest importance in all uterine affections. DIRECTIONS FOR. USE. Take half a tea-spoonful, three times a day, for a month; then increase the quantity to a tea-spoonful each dose, and continue until the system is fully restored to regularity. These Drops, in connection with our Stimulating Liniment, and our Health Restorative or Vegetable Syrup, taken accord- 6 ■12 DISEASE AND TTS TREATMENT. ing to the directions accompanying each, is competent to re- store the most deranged state of the system—which has been accomplished in a great number of cases. When the patient is very Nervous—it is advisable to use our Liniment for Nervous affections, instead of Stimulating Liniment—but otherwise, the latter is preferable. In cases of Fluor Albus and Prolapsus Uteri—and in fact all uterine affections, these Drops have been administered to good advantage—we have the evidence of cases being re- lieved in a few days by these Drops, and our other remedies. ALTERATIVE DROPS. The object intended to be effected by these Drops is, to restore the circulating fluids to a pure state. They are taken in small doses—and it is said, by some who have used them, that the scrofula has been cured by these drops alone. DIRECTIONS FOR USE. These Drops are taken internally, in half tea-spoonful doses, two or three times a day—children from four to six drops—and continued for a considerable length of time. In many chronic complaints, such as liver complaint, scro- fula, white swellings, inflammatory rheumatism, gout, and in cases of eruptions on the surface of the body, they act power- fully in cleansing the blood and circulating fluids; and though their beneficial effects are not so suddenly manifested as are many of our preparations, they are no less certain of pro- ducing the most salutary effects, when taken in conjunction with the use of our external remedies. ESSENCE OF LIFE. This remedy was prepared several years ago, but we were determined not to offer it for sale, until its virtues were fully tested. The large number of chronic complaints which have recently come under our treatment, have fully established its character, and we now cheerfully recommend it in cases of OUR REMEDIES. 43 dyspepsia, nervous affections, faintness and distress at the stomach, asthma, palpitation of the heart, bilious and wind cholic, etc. Its powers to relieve in the above cases are very ready; and though we do not recommend it to cure these complaints without the aid of other medicine, we can with confidence say, that it is a most grateful and ready palliative, affording almost instantaneous relief, in many cases, from extreme suf- fering. DIRECTIONS FOR USE. In ordinary cases—it is taken in doses of from six to ten drops, in warm water, or on sugar, once in ten minutes, until relief be afforded. In cases of Bilious and Wind Cholic, or extreme pains in the chest—take a tea-spoonful once in fifteen minutes, diluted in water. Keep the vial well corked. NERVE SANATIVE. A powerful remedy for tic douloureux, fits of every kind, nervous affections, and delirium. The agents composing this invaluable preparation, have been concentrated to a far greater extent than any of our remedies heretofore prepared; and it is only to be taken in very small doses. DIRECTIONS FOR USE. For Nervous Affections—one drop, diluted in warm water, may be taken three or four times a day. For Tic Douloureux—apply externally, to the parts af- fected, three or four drops, and then apply our Nerve Lini- ment freely. Take also half a tea-spoonful of the Essence of Life. For Spasmodic Fits—take two drops, diluted in water, once in twenty-five or thirty minutes, which will at once reduce the spasms; after which, take one drop, two or three 44 DISEASE AND ITS TREATMENT. times a day, as a preventive. In extreme cases, if this dose be not sufficient to immediately arrest the fits, the close may be doubled, or even thrice the quantity given, and repeated until relief be gained. In extreme cases of Pleurisy—from two to six drops may be taken once in twenty minutes, and a few drops may be applied to the side, with the Nerve Liniment. In all cases we recommend a full application of our Nerve Liniment. These Drops, accompanied with the Nerve Liniment, have frequently arrested fits in a very few minutes. In cases of long standing Delirium—a full application of the Nerve Liniment over the whole body, including the head, (after shaving off the hair,) two or three times a day, is absolutely necessary. Take the Essence of Life, in half tea-spoonful doses,three or four times a day; at the same time take two drops of the Nerve Sanative two or three times a day. Some might be led to suppose that the Sanative contained deleterious drugs, from the small doses recommended. To relieve all such, we pledge ourselves that this is not the case. BROWN WASH. This preparation is efficacious in cases of gonorrhea and syphilis, and was intended expressly for those diseases, but may be used to good advantage in indurated ulcers, etc. The Wash is also exhibited internally, in doses of a tea- spoonful two or three times a day. LOTION FOR DYSPEPSIA. This remedy has been advantageously applied to the head and glandular parts of the face and neck, in cases of long standing dyspepsia, and especially where the complaint has caused a depression of spirits in the patient. It is applied over the head generally, and may be used to advantage in conjunction with the Nerve Sanative, in many nervous affections. OUR REMEDIES. 45 CANCER PREPARATIONS. Our preparations for cancers are composed of a Liniment, Syrup, Plaster, Poultices, etc., and are calculated to remove pain in the region of the cancer in a very short time, but as it is the business of thousands to pretend to cure cancers, we have avoided giving publicity to our preparations, as with- out the most scrupulous attention to the prescriptions, there is but little chance for a cure; and we are well aware of the difficulty which almost always attends these cases of inducing the patient to persevere in a course long enough to effect a fair trial. The foregoing general directions will enable the practi- tioner to apply and exhibit our remedies with safety and benefit to the patient, and though some variations may be ne- cessary to most cases as they occur, the fact that there is no one of these preparations which contains any medicine that is poisonous or deleterious to the human system, and that there can be no danger arising from applying as much of our exter- nal preparations as the absorbing pores will receive, renders them perfectly safe, even if they are administered by unskil- ful hands. CHAP. II. FEVER. Fever; a disease characterized by an increase of heat, an accelerated pulse, a foul tongue, and an impaired state of sev- eral functions of the body. The varieties are numerous.— The principle divisions are into continued and intermittent fevers. Continued fevers have no intermission, but exacerba- tion comes on usually twice in one day. The genera of continued fever are, 1st, Synocha, or inflam- matory fever, known by increased heat; pulse frequently strong and hard; urine highly colored; senses not much im- paired: 2d, Typhus, or putrid-tending fever, which is conta- gious, and is characterized by moderate heat; quick, weak and small pulse; senses much impaired, and great prostration of strength: 3d, Synochus, or mixed fever. Intermittent fevers are known by cold, hot and sweating stages in succes- sion, attending each paroxysm, and followed by an intermis- sion or remission. There are three genera of intermitting fevers, and several varieties: 1st, Quolidiana; a quotidian ague. The paroxysms return in the morning, at an interval of about twenty-four hours. 2d, Tertiana; a tertian ague. The paroxysms commonly come on at mid-day, at an inter- val of about forty-eight hours. 3d, Quartana; a quartan ague. The paroxysms come on in the afternoon, with an interval of about seventy-two hours. The tertian ague is most apt to prevail in the spring, and the quartan in autumn. When these fevers arise in the spring, they are called vernal; and when in the autumn, they are known by the name of autumnal. Intermittents often prove obstinate and are of long duration in warm climates; and they not unfrequently resist every mode of cure, so as to become very distressing to IS DISEASE AND ITS TREATMENT the patient, and, by the extreme debility which they thereby induce, after giving rise to other chronic complaints. It seems to be pretty generally acknowledged, that marsh mias- mata, or the effluvia arising from stagnated water, or marsh ground, when acted upon by heat, are the most frequent exci- ting causes of this fever. A watery, poor diet, great fatigue, long watching, grief, much anxiety, exposure to cold, lying in damp rooms or beds, wearing damp linen, the suppression of some long accustomed evacuation, or the recession of erup- tions, have also been ranked among the exciting causes of in- termittents: but it is more reasonable to suppose that these circumstances act only by inducing that state of the body which predisposes to these complaints. One peculiarity of this fever is its great susceptibility of renewal from very slight causes, as from the prevalence of an easterly wind, even without the repetition of the original exciting cause, In this circumstance, intermittents differ from most other fevers, as it is well known that, after a continued fever has once oc- curred, and been removed, the person so affected is by no means so liable to a fresh attack of the disorder, as one in whom it had never taken place. We have not yet attained a certain knowledge of the proximate cause of an intermittent fever, but a deranged state of the stomach, and primas viae is that which is most generally alledged. Each paroxysm of an intermittent fever is divided into three different stages, which are called the cold, the hot, and the sweating stages, or fits. The cold stage commences with languor, a sense of debility and sluggishness in motion, fre- quent yawning and stretching, and an aversion to food. The face.and extremities become pale, the features shrunk, the bulk of every external part is diminished, and the skin over the whole body appears constricted, as if cold had been ap- plied to it. At length the patient feels very cold, and uni- versal rigors come on, with pains in the head, back, loins and joints, nausea and vomiting of bilious matter; the respiration is small, frequent and anxious; the urine is almost colorless; sensibility is greatly impaired; the thoughts are somewhat FEVER. 49 confused; and the pulse is small, frequent, and often irregular. In a few instances, drowsiness and stupor have prevailed in so high a degree as to resemble coma or apoplexy; but this is by no means usual. The symptoms abating after a short time, the second stage commences with an increase of heat over the whole body, redness of the face, dryness of the skin, thirst, pain in the head, throbbing in the temples, anxiety and restlessness; the respiration is fuller and more free, but still frequent; the tongue is furred, and the pulse has become reg- ular, hard and full. If the attack has been very severe, then perhaps delirium will arise. When these symptoms have continued for some time, a moisture breaks out on the fore- head, and by degrees becomes a sweat, and this at length ex- tends over the whole body. As this sweat continues to flow, the heat of the body abates, the thirst ceases, and most of the functions are restored to their ordinary state. This consti- tutes the third stage. When intermittents continue for any length of time, they are apt to induce other complaints, such as a loss of appetite, flatulency, scirrhus of the liver, dropsical swellings, and general debility, which now and then prove fatal in the end, particularly in warm climates; and, in some cases, they de- generate into continued fevers. Relapses are very common to this fever, at the distance of five or six months, or even a year. Autumnal intermittents are more difficult to remove than vernal ones, and quartans more so than the other types. It is always desirable to suspend a paroxysm if possible, not only to prevent mischief, but also that there may be more time for the use of the most effectual remedies. When, therefore, a fit is commencing, or shortly expected, we may try to obviate it by some of those means which excite movements of an opposite description in the system: determining the blood powerfully to the surface of the body, by various stimulating remedies, will often succeed. Should the paroxysm have already come on, and the cold stage be very severe, the warm bath, and cordial diaphoretics, in repeated moderate doses, 7 50 DISEASE AND ITS TREATMENT. may assist in bringing warmth to the surface. In the inter- mission, in conjunction with a generous diet, moderate exer- cise, and other means calculated to improve the vigor of the system, tonics are the remedies especially relied upon. Febris synocha; inflammatory fever—a species of contin- ued fever, characterized by increased heat; pulse frequent, strong, hard; urine highly colored; senses not impaired. This fever is so named from its being attended with symptoms de- noting general inflammation in the system, by which we shall always be able readily to distinguish it from the nervous or putrid. It makes its attack at all seasons of the year, but is most prevalent in the spring; and it seizes persons of all ages and habits, but more particularly those in the vigor of life, with strong elastic fibres, and of a plethoric constitution. It is a species of fever almost peculiar to cold and temperate climates, being rarely, if ever, met with in very warm ones, except among foreigners lately arrived, and even then, the inflamma- tory stage is of very short duration, as it very soon assumes either the nervous or putrid type. The exciting causes are sudden transitions from heat to cold, swallowing cold liquors when the body is much heated by exercise, a too free use of vinous and spirituous liquors, great intemperance, violent pas- sions of the mind, the sudden suppression of habitual evacua- tions, and the sudden repulsion of eruptions. It may be doubted if this fever ever originated from personal infection; but it is possible for it to appear as an epidemic among such as are of a robust habit, from a peculiar state of the atmos- phere. It comes on with a sense of lassitude and inactivity, succeeded by vertigo, rigors and pains over the whole body, but more particularly in the head and back; which symptoms are shortly followed by redness of the face and eyes, great restlessness, intense heat, and unquenchable thirst, oppression of the breathing, and nausea. The skin is dry and parched; the tongue is of a scarlet color at the sides, and furred with white in the center; the urine is red and scanty; the stomach is costive; and there is a quickness, with a fullness and hard- ness in the pulse, not much affected by any pressure made on FEVER. 51 the artery. If the febrile symptoms run very high, and pro- per means are not used at an early period, stupor and delirium come on, the imagination becomes much disturbed and hur- ried, and the patient raves violently. The disease usually goes through its course in about fourteen days, and terminates in a crisis, either by diaphoresis, diarrhea, hemorrhage from the nose, or the deposit of a copious sediment in the urine; which crisis is usually preceded by some variation in the pulse. As the disease advances, we must attempt to promote the other discharges, particularly that by the skin. Impres- sions on the senses, particularly the sight and hearing, bodily and mental exertion, etc. must be guarded against as much as possible. When the head is much affected, besides the general treatment, have the head shaved, and perhaps stimulate the lower extremities. In like manner, any other organ, being particularly pressed upon, may require additional means to be used for its relief, which will be different in different cases. Typhus; a species of continued fever—characterized by great debility, a tendency in the fluids to putrefaction, and the ordinary symptoms of fever. It is to be readily distinguished from the inflammatory, by the smallness of the pulse, and the sudden and great debility which ensues on its first attack, and in its more advanced stage, by the petechia, or purple spots, which come out on various parts of the body, and the fetid stools which are discharged; and it may be distinguished from the nervous fever, by the great violence of all its symptoms, on its first coming on. The most general cause that gives rise to this disease, is contagion, applied either immediately from the body of a per- son laboring under it, or conveyed in clothes, merchandise, etc.: but it may be occasioned by the effluvia arising from either animal or vegetable substances, in a decayed or putrid state; and hence it is, that, in low and marshy countries, it is apt to be prevalent, when intense and sultry heat quickly succeeds any great inundation. A want of proper cleanliness, and confined air, are likewise causes of this fever; hence it 52 DISEASE AND ITS TREATMENT. prevails in hospitals, jails, camps, and on board of ships, espe- cially when such places are much crowded, and the strictest attention is not paid to a free ventilation and due cleanliness. A close state of the atmosphere, with damp weather, is like- wise apt to give rise to putrid fever. Those of lax fibres, and who have been weakened by any previous debilitating cause, such as poor diet, long fasting, hard labor, continued want of sleep, etc., are most liable to it. On the first coming on of the disease, the person is seized with languor, dejection of spirits, amazing depression, and loss of muscular strength, universal weariness and soreness, pain in the head, back and extremities, and rigors; the eye appears full, heavy, yellowish, and often a little inflamed; the temporal arteries throb violently; the tongue is dry and parched; respiration is commonly laborious, and interrupted with deep sighing; the breath is hot and offensive, the urine is crude and pale, the body is costive, and the pulse is unusu- ally quick, small and hard, and now and then fluttering and unequal. Sometimes a great heat, load, and pain are felt at the pit of the stomach, and a vomiting of bilious matter en- sues. As the disease advances, the pulse increases in fre- quency, (beating often from one hundred to one hundred and thirty in a minute.) There is a vast debility, a great heat and dryness in the skin, oppression at the breast, with anxiety, sighing, and moaning; the thirst is greatly increased; the tongue, mouth, lips, and teeth are covered with a brown or black tenacious fur; the speech is inarticulate and scarcely intelligible; the patient mutters much, and delirium ensues. The fever continuing to increase in violence still more, symp- toms of putrefaction show themselves; the breath becomes highly offensive; the urine deposits a black and fetid sediment; the stools are dark, offensive, and pass off insensibly; hemorr- hages issue from the gums, nostrils, mouth, and other parts of the body; livid spots, or petechia, appear on its surface; the pulse intermits and sinks; the extremities grow cold; hiccoughs ensue, and death at last closes the scene. When this fever does not terminate fatally, it generally, FEVER. 53 in cold climates, begins to diminish about the commencement of the third week, and goes off gradually toward the end of the fourth, without any very evident crisis; but in warm climates, it seldom continues above a week or ten days, if so long. Our opinion as to the event, is to be formed by the degree of violence in the symptoms, particularly after petechia ap- pear, although, in some instances, recoveries have been effect- ed under the most unpromising appearances. An abatement of febrile heat and thirst, a gentle moisture diffused equally over the whole surface of the body, loose stools, turbid urine, rising of the pulse, and the absence of delirium and stupor, may be regarded in a favorable light. On the contrary, pete- chia, with dark, offensive, involuntary discharges by urine and stool, fetid sweats, hemorrhages, and hiccoughs, denote the almost certain dissolution of the patient. The appearances usually perceived on dissection, are inflammations of the brain and viscera, but more particularly of the stomach and intestines, which are now and then found in a gangrenous state. In the muscular fibres there seems likewise a strong tendency to gangrene. In the very early periods of typhus fever, it is often possi- ble, by active treatment, to cut short the disease at once; as the disease proceeds, we must keep up the functions, and at- tempt to restore that of the skin, and the other secretions, as the best means of moderating the violence of vascular action. It may be sometimes advisable to employ the tepid bath, to promote the operation of the diaphoretic medicines. If, under the use of the measures already detailed, calculated to lessen the violence of the vascular action, the vital powers should appear materially falling off, recourse must then be had to a more nutritious diet, with a moderate quantity of wine, and cordial or tonic medicines. There is generally an aversion to animal food, whence the mucilaginous vegetable substances, as arrow-root, etc., rendered palatable by spice, or a little wine, or sometimes mixed with a little milk, may be directed as nourishing and easy of digestion. If, however, there be 54 DISEASE AND ITS TREATMENT. no marked septic tendency, and the patient is cloyed with these articles, the lighter animal preparations, as calves' foot jelly, veal broth, etc., may be allowed. The extent to which wine may be carried, must depend on the urgency of the case, and the previous habits of the indi- vidual; but it will commonly not be necessary to exceed half a pint, or a pint at most, in the twenty-four hours; and it should be given in divided portions, properly diluted, made perhaps, into negus, whey, etc., according to the liking of the patient. The preference should always be given to that which is of the soundest quality, if agreeable; but where wine cannot be af- forded, good malt liquor, or mustard whey, may be substituted. Some stimulant medicines, as aromatics, serpentaria, etc., may often be used with advantage, to assist in keeping up the circulation; also those of atonic quality, as columba, cusparia, etc., occasionally in their lighter forms, but more especially the acid. These are, in several respects, useful, by promot- ing the secretions of the prima? vise, etc.—they quench the thirst, remove irritation, and manifestly cool the body; and in the worst forms of typhus, where the putrescent tendency appears, they are particularly valuable, from their antiseptic power; they are also decidedly tonic, and, indeed, those from the mineral kingdom powerfully so. These may be given freely as medicine; the carbonic acid, also, in the form of brisk fermenting liquors; and the native vegetable acids, as they exist in ripe fruits, being generally very grateful, may consti- tute a principal part of the diet. In the mean time, to obviate the septic tendency, great attention should be paid to cleanli- ness and ventilation, and keeping the bowels regular by mild aperients or clysters, of an emollient or antiseptic nature; and where aphtha appear, acidulated gargles should be di- rected. If the disease inclines more to the nervous form, with much mental anxiety, tremors, and other irregular affec- tions of the muscles, or organs of sense, the antispasmodic medicines may be employed with more advantage, to call a greater portion of nervous energy to the lower extremities by the pediluvium, or other mode of applying warmth, or occa- FEVER. 55 sionally by friction and stimulating remedies. But if there should be much increased vascular action in the brain, more active means will be required, and it, will be always right to have the head shaved. In like manner, other important parts may occasionally require local means of relief. Urgent vo- miting may, perhaps, be checked by the effervescing mixture; a troublesome diarrhea, by sudorifics, and warm applications to the bowels; profuse perspiration, by the infusion of a dia- phoretic regimen. Nervous Fever; a variety of the typhus mitior of Cullen, but by many considered as a distinct disease. It mostly be- gins with loss of appetite, increased heat and vertigo; to which succeeds nausea, vomiting, great languor, and pain in the head, which is variously described by some, like cold water pouring over the top—by others, as a sense of weight. The pulse, before little increased, now becomes quick, febrile, and tremu- lous; the tongue is covered with a white crust, and there is great anxiety about the praecordia. Towards the seventh or eighth day, the vertigo is increased, and tinnitus aurium, cophosis, delirium, and a dry and tremulous tongue take place. The disease mostly terminates about the fourteenth day. Dengue Fever. This name has been given to a disease which appeared in the year 1828, in the West Indies, and in the southern States of North America: it has also been called the dingee, the danga, the dandy, the bouquet, and the bucket fever. This disease was remarkable for the suddenness of its attacks, the. great numbers affected, the severity of the symp- toms, and the rareness of death from it. It would seem from the reports of those who have seen most of this disease, and whose judgment may be relied on, that the dengue has some affinities with the yellow fever. The symptoms as noticed in Havanna were first, great languor, chilliness and pain in the tendons of the smaller joints; following these, were burning heat and redness of the skin, pains in the muscles of the limbs, or pain in the forehead, and a loathing or vomiting of what- ever was taken into the stomach. The fever continued for 56 DISEASE AND ITS TREATMENT. one, two, or three days, and then usually terminated with abundant sweating, which freed the patient, likewise, from his pains. But many, after leaving their beds, suffered by a re- newal of their pains, which, in some, have become chronic; others have also had a renewed attack of the fever. " The most usual mode of attack, however," says Dr. Stedman, of Santa Cruz, "which appears not a little singular, was the fol- lowing: A person in perfect health would suddenly feel a stiffness, amounting almost to pain, in one of his fingers, and most frequently in his little finger. The stiffness increased, and was accompanied with an intense degree of pain, which spread rapidly over the whole hand, and up the arm to the shoulder. The fingers in both hands, in a few hours, became swelled, stiff and painful, preventing all attempts at bending the joints." To this succeeded restlessness, depression of spirits, nausea, vomiting, shivering, great heat, intense head- ache, most acute pain in every joint. The most distressing symptoms were intense pain in the eye-balls and back, the eyes seeming to the patient enlarged, filling the sockets, and as if ready to burst. Quite a remarkable symptom was the feeling of intense cold, while at the same time the skin was intensely hot. These symptoms continued from twenty-four to thirty-six hours. The patient now remained languid, irri- table and restless for about three days, when it was not un- common for a new attack to come on, accompanied by an efflorescence, beginning at the palms of the hands, and ex- tending thence over the wbole body. Secondary symptoms, consisting principally of pain and stiffness in the limbs and body followed, which, in many cases, continued for weeks, and made the patient most uncomfortable. Sometimes there was distressing itching; and in some cases there was swelling of the prsepuce and scrotum, and in others, a discharge from the urethra, resembling gonorrhea. Dr. Steidman considers the disease contagious. Stimulating embrocations, mustard poultices, and the like, were employed in the treatment of this disease; the latter were applied to the temples, to relieve the pain in the eye- FEVER. 57 balls, to the back, the back of the neck, etc., as indicated, and always with advantage. TREATMENT. In the various forms of fever enumerated in the preceding article, we have noticed that there is a very great similarity of treatment adopted by the most eminent physicians. The variations are so trifling, that he wrho could successfully treat one form by the method pointed out, would not be at a loss to adapt the means in his possession, to another. In our ex- perience in fevers, we have noticed the same fact; we have never found any difficulty in overcoming all forms of fever, by an application of our remedies for fever; and we never have been at a loss, to so modify them as to meet the variety of cases which come within our notice. Note.—It would be irrelevant to the development of a cor- rect idea, to go into a minute detail of the nosology of that class of diseases, called by Cullen, Pyrixia. Its classification into orders, and those into genera, and those again, into spe- cies, are but an accumulation of names for many slight varia- tions of type, arising, probably, from peculiar constitutional causes. Whatever be their form, their nature is the same. The causes and progress of fever have hitherto remained inexplicable. No man has had a power of discernment suffi- cient to penetrate the mystic phenomena. When the febrile and other symptoms have disappeared, or during the inter- mission, what becomes of the disease? why, at its appointed hour, does it invariably occur? These questions have never been answered. Waving the assumption of any hypothesis on these controverted points, we will proceed to the treatment we have uniformly found successful, for the removal of these distressing complaints. Were we to attempt a disquisition of their modus operandi, here again we should approach a point of extensive controversy. One author strenuously ad- vocates lymphatic absorption, another nervous absorption, and another the nervous sympathy, and the like. For obvious 8 58 DISEASE AND ITS TREATMENT. reasons, we have every thing doctrinal for the physiologist to speculate upon. In the adaptation of our remedies for fevers, we embrace the generally received opinion; and it is our conviction, re- sulting from practice, that fevers differ only in the degree and duration of their violence, and, consequently, the same course of treatment will apply, to a certain extent, in every form of the malady. We acknowledge that it requires more credulity than peo- ple are generally habituated to exercise, to believe that the worst forms of fever can be cured, without the exhibition of either emetics, cathartics, or injections. Some gentlemen of professed science, unacquainted with our remedies, argue that such results are opposed to the prin- ciples of science. But the vast number of cases which have yielded to this mode of treatment, have established the fact in the minds of all who have made a fair trial—we say all, for we have never known or heard of a single failure, where our remedies have been properly used according to directions, and we know of many cases which have been cured, after having been pronounced incurable by the ablest physicians in the United States. 1st. Apply our Fever Liniment freely to the body and to the soles of the feet, with much friction; bind plasters of the same on the soles the feet, and place warm bricks to the feet and sides. 2d. Take a tea-spoonful of the Diaphoretic Drops, diluted in warm water sweetened, once in twenty minutes, until a profuse perspiration takes place. This course will soon re- duce the febrile symptoms, and relieve the patient from pain. In some cases, although the external heat may appear to be increased for a short time, and produce an impression that the fever is increased, yet upon examining the pulse, it will be found to indicate the contrary. 3d. The same Liniment may be applied to the stomach on a plaster, which will supersede the necessity of administcrhi"- an emetic. FEVER. 59 4th. If the application of the Liniment do not give full relief, it may be repeated in four hours, or oftener, if neces- sary. In extreme cases of congestive or typhus fever, the saline bath may be used to advantage, which consists of warm water, in which three quarts of salt are adder! to twelve pails- ful of water; in this the patient may be bathed for the space of fifteen minutes; then wipe dry, rubbing the body well with cloths, and applying the Liniment freely. 5th. After the symptoms of disease are removed, the pa- tient may be washed off with soap suds, then with salt and water, and wiped dry; after which, apply as before, the Stimu- lating or Fever Liniment, giving the preference to the former if at hand, being more tonic and less diaphoretic in its effects. Many persons, after undergoing a copious perspiration by means of the Fever Liniment, upon its subsiding, have appre- hensions of taking cold—to prevent which, it is important for them to make a free application to the body, of the Stim- ulating Liniment, as that previously applied has become ab- sorbed into the system. This course renders the patient less liable to the effects of the atmosphere, and is indispensably necessary to invigorate by its tonic properties, and overcome the debilitating and febrile symptoms. This course should be repeated once or twice a day for a while, even if no par- oxysm of fever should occur, after the attack is arrested. In cases of fever and ague, where it can be done, let the Fever Liniment be applied, accompanied by our Diaphoretic Drops, in the manner first stated, about half an hour previous to the time of the expected chill, until a profuse perspiration is pro- duced; or if the chill arrive before the application can be made, then, during the paroxysm of the chill or succeeding fever, apply the Fever Liniment in the same manner, which will very generally arrest the disease, and entirely prevent a return of chill and fever; and, by the patient applying the Liniment once or twice a day, for a few days, he will be en- tirely restored to health and strength. < In severe cases of pleurisy, apply the Fever or Stimulating Liniment over the region of pain, with a warm brick, or a 60 DISEASE AND ITS TREATMENT. bag of hops or meal, which will directly arrest the extreme suffering, and, if followed up in a similar manner to the fore- going, according to the violence of the attack, and relief ex- perienced, will overcome the disease, and entirely supersede any resort to the lancet, or to blistering. Our remedies for fever are the most valuable of any of our preparations, and when they become fully known, will be so estimated by the various orders of physicians, as well as by the general people. In many severe cases of fever, it is recommended to soak the feet, and wash the whole surface of the body in warm water, before the first application of the Liniment. YELLOW FEVER. This fever is one of a specific character, and generally con- fined to situations in which much moisture is joined to great heat. It prevails in Asia, the West Indies, South America, in the southern, and sometimes in the northern parts of the United States. It is endemial in many portions of the globe, especially in the tropical climates, and sometimes it is epidemic in northern latitudes, as at Baltimore, Philadelphia, and New-York. It is most common in sea-ports and near large bodies of water, but occasionally it is found in inland situations. It is said to differ materially from the endemial remittant of tropical countries, and is of course not merely an exaggerated form of the bilious remittent of such places. It differs from the endemial remittent of the West Indies, in only attacking strangers to such climates. The natives and such as have lived long in similar situations, are altogether exempt from its attack; and, should the stranger survive the dangers of an attack, he remains generally safe for the future, though not exempt from the endemial remittent of the place. Should the stranger escape for a year or two, he becomes acclimated, and is no longer liable to be attacked by the scourge. YELLOW FEVER. 6- The yellow fever has heretofore been looked upon as con- tagious; but this notion is now generally abandoned by those best qualified to' judge of the fact. Its rapid spread may be accounted for, on the principles which make it an epidemic. The disease differs essentially from all others in its mode of attack, and in the violence of its symptoms. In almost every other febrile affection, as a general rule, the risk is in propor- tion to the violence of the symptom; but the masked or insid- ious form of the yellow fever is most commonly the least manageable, and consequently the most dangerous. Hence the "walking cases" are almost sure to prove fatal. It is said there are three modes of attack in yellow fever; and the phenomena of each may vary, as the remote cause may have been more or less active or concentrated. They may also be influenced by individual habits or constitution, or by the force of occasional or exciting causes; and hence the disease is sometimes found to run its course very rapidly; that is, in from two to five days, some of the cases terminating in black vomit. In this form of the disorder the symptoms are gen- erally less terrible and less distinctly marked, though more certainly and speedily fatal; or it may run on to the fifth or seventh day; and though the sufferings are of a more acute kind, the danger is less, as more time is given for the applica- tion of remedies; or it may present, like regularly-formed remittents, exacerbations, and remissions. If it assume this form, it may run on t,o the ninth or eleventh day. The first form observes no very regular time of attack, the evening is however the most common. The second generally takes place in the afternoon, and the third usually in the morning. The mode of attack is generally marked by the same train of symptoms, differing more in force than in character, if we except the first, which often has the peculiarity of betraying itself by scarcely any outward signs, except weakness,' slight headache or nausea. This insidious character lulls the patient and his friends into fatal security. The patient has been known to walk about until within a few minutes of dissolu- tion. The unmasked or violent attack of the yellow fever is, 62 DISEASE AND ITS TREATMENT therefore, less to be dreaded, than the seemingly mild form, as the derangement of the system is more palpable, though it is always highly dangerous. This disease differs in its attack from almost every other form of fever, as it is seldom ushered in by a well-defined chill, though the sensation of cold will sometimes remain a long time before reaction will take place. Much languor is always experienced, with intense headache, distress about the precordia, and the eyes are of a peculiarly red color. The heat of the skin is seldom great in the be- ginning, but it soon increases in intensity. The pulse is rarely open and strong; indeed, it appears to the careful ob- server, rather more feeble than usual, and is thereby some- times betrayed into a dangerous security. The face assumes a peculiar flush, which is different from the redness of ordin- ary fever. This flushing gives a very marked character to the countenance, and can never be mistaken, by an eye ex- perienced in this disease, for symptoms of common fever; on the contrary, it always denotes a high degree of yellow fever. The tongue is usually moist and clammy; but rarely dry, rough or red, at the commencement, though these conditions of this organ are sure to follow in a short time. The skin is for the most part dry and harsh, though it occasionally is found wet with hot perspiration. This sweat is sometimes early in its appearance, and, at times, extremely profuse, but it neither abates the action of the heart and arteries, nor mit- igates the local sufferings—as headache, pain in the limbs, or oppression in the lungs. It therefore betrays the malignancy of the disease. There is seldom an abatement at any period of the dav which would amount to a remission, though there is frequently an exacerbation that is very alarming from its intensity; and this may happen twice or even thrice in the twenty-four hours. Where this happens, the disease proceeds with hasty strides to its fatal termination; for should not rem- edies at this time very soon after their application abate the severity of the symptoms, more fatal symptoms quickly su- pervene; the eye becomes more red; lividity is added to the deep toned color of the cheek; the tenderness is much in- YELLOW FEVER. 63 creased by pressure over the region of the stomach; nausea and vomiting commence or intervene; the patient tosses him- self into every position; delirium ensues; the urine becomes intense in color, and small in quantity; the extremities lose their heat; the gums become swollen and livid, the tongue red or brown, and dry; thirst insatiable, and the drinks are ejected perhaps as fast as swallowed. After a continuance of these symptoms for a few hours, the system seems to make a compromise with the disease, and passively yields, to its power. There is no diminution of danger at this moment, though the system seems less morbidly excited; for if the suffering be less, danger is increased. Now the stomach gives way; the most tormenting nausea and thirst, with al- most incessant vomiting, take place. The fluids discharged are, for the most part, nothing but the drinks the patient has swallowed; for these, even in the beginning, are seldom tinged with bile. But the threatening change soon follows— the fluids become thicker, and somewhat viscous, and are now found to have mixed with them, flaky substances of a dark color. These flaky substances, there is reason to believe, are portions of the viscous coat of the stomach, detached, and made to mix with the ejected fluids by the effort of vomit- ing. The urine at this time is usually very scanty, or may be suppressed; the bowels are tardy, or yield a blackish look- ing substance, of considerable tenacity, and much resembling tar. The whole surface of the body with the exception, per- haps, of the abdomen, is colder than natural; sometimes dry, sometimes moist; the hands and feet are deathly cold, and mottled with stagnating blood; the pulse is feeble, fluttering, or extinct. Sleep forsakes the patient, or he doses only to suffer more; his respiration is hurried, or preternaturally slow. Sometimes the patient remains in the full possession of reason, until the last moment of life. Some die tranquilly, declaring that nothing ailed them; while others die in great agony. This happens generally when delirium is present, and when the brain, from sympathy, seems to sustain the great force of attack. The patient may become more tranquil, 64 DISEASE AND ITS TREATMENT. from an evident mitigation of all the severer symptoms, and this short-lived trance, gives rise, in the inexperienced, to hopes that are never to be realized; for now the yellowness of the skin begins to show itself, and becomes the harbinger of the dreaded "black vomit." This matter is thrown from the stomach, sometimes in incredible quantities, and in vari- ous shades of color. It is ejected with very little effort, and the patient, for the most part, denies the existence of pain. Black vomit does not always precede death. But when this is the case, its place is supplied by the eructation of prodigious quantities of gas, rapidly and constantly secreted by the stomach. The gums and other portions of the body, at this time yield considerable quantities of blood, which renders the aspect of the patient truly hideous. The teeth become incrusted; the tongue grows black and dry; the pulse is slow and feeble, or at the wrist perhaps imperceptible; the skin and extremities are cold; coma or low muttering delirium takes place; sometimes there are convulsions; finally death ensues. This fever is not inevitably fatal, though the prognosis must always be unfavorable. If the disease have commenced in an open undisguised form, the chance is increased; but if the attack be insidious, the danger is almost always in propor- tion to the absence of prominent or decided symptoms. If the disease assume, or can be made to put on a regular form, that is, if its remissions and exacerbations be in pretty regular order, though the symptoms run high, there appears a better chance of increasing the one, and moderating the other. But, on the other hand, if the disease manifest no tendency to regular remission, the risk is greatly augmented. If the patient sigh deeply immediately after waking, and before he has recovered the power of speech, the presage is bad; or if he complain much of soreness and pain, without the part having any morbid appearance, it is equally unfavorable. Those whose arms become rigid recover seldom; and those who have an entire suppression of urine, never. Black vomit is always a very unfavorable symptom, especially when at- YELLOW FEVER. ^ tended by hiccough; but it is not necessarily a fatal one, par- ticularly in younger people. The "puking of wind" as it is called, is perhaps as deadly a symptom as the black vomit. On the other hand, should there be a general abatement of the symptoms, especially less headache, with a softened skin, a generally and equally distributed warmth over the body, diminution of thirst, without nausea and vomiting, the tongue beginning to clean, less tenderness in the epigastrium, bilious foecal discharges, a free flow of bright colored urine, a moder- ate and generally diffused perspiration after the* abatement of the exacerbation, the disease may be considered less desperate, and as tending to a healthy solution. The pulse in this disease, is less affected than in most severe complaints. Indeed but little dependence can be put upon it. Sometimes it will resemble the appearance of health at the worst stages of the complaint; at others, it has been known to have entirely ceased, and afterwards the patient recovered. TREATMENT. An eminent writer on the treatment of yellow fever, has made the following observations: "The treatment of this disease is very far from being as efficacious or as certain as its danger requires; yet it is not so fatal, under favorable circumstances, as might at first sight be supposed. In tropical climates, it rages among strangers almost exclusively; and these, for the most part, are of a de- scription unable to procure the means of mitigating or avert- ing danger. In northerly situations, where the disease is, as it were, accidental, the mortality, under the best circumstan- ces, is considerably less, though very much too great. We may attribute some portion of the mortality to the views that have been taken of the habits and nature of the disease. The supposition of its contagion, increases the mortality, by with- holding the necessary aid from the afflicted, under apprehen- sion of danger; while others are sacrificed through the means of a multitude of hypotheses. The opinion is now, however, daily gaining ground, that yellow fever is essentially an in- 9 66 DISEASE AND ITS TREATMENT. flammatory disease, and one which requires a vigorous and strictly antiphlogistic plan of treatment. But neither a cor- rect pathology, nor the best concerted means, will avail, if the proper time for their application be lost. Yellow fever, as stated by the best authors, must be looked upon as an exqui- site gastritis; it is for the relief of this condition of the stomach almost exclusively, that remedies are to be sought. The oppressed pulse in this disease, always acquires vigor by the loss of blood. The quantity to be taken at any given time, cannot be readily defined; for this state of the arterial system may require a large quantity of blood to relieve it, or the pulse may become free and open by the abstraction of only a few ounces. The management of the bleeding must, therefore, be left to the discretion of the medical attendant. If the pulse rise, as it is wont to do under this condition of the system, by the loss of blood, its abstraction should be continued until it becomes soft under the finger. Nor can any rule be laid down for the repetition of bleeding, but one— namely, that recourse must be had to it whenever the system reacts with force, by which every symptom becomes aggra- vated, even if this occur several times in twenty-four hours. It is mainly owing to not taking down the excess of action at the heart and arteries, when it occurs, that fatal disorgani- zation takes place so frequently; therefore, every paroxysm should be carefully watched, that no one pass without having the force of the pulse abated, by the loss of blood; for it may be confidently said, that the system never reacts forcibly in this disease when it will not bear the abstraction of blood, either generally or tropically. If tropical bleeding be resort- ed to, it must be from the epigastrium; therefore, either leeching or cupping must be the mode of abstraction. This state of the system is rarely found, however, after the expi- ration of eight and forty hours, unless the disease have been vigorously treated by previous blood letting. Should this period have been lost, bleeding from the general system can rarely be successful—tropical bleeding alone now promises relief; and this may be tried at any period of the disease, if YELLOW FEVER. 67 the epigastrium remain active. As regards the feebleness of reaction, as just stated, we must not be mistaken in its causes in the beginning of this disease; as it is almost sure to depend on the depressed slate of the pulse; for after the blood has been taken, in an appropriate quantity, the heat of the skin, and the activity of the pulse, will both increase. But it is always proper when reaction is feeble, the skin cooler than natural, and the extremities perhaps cold, but certainly preter- naturally cool, to use external stimuli, with a view of aid- ing the powers of the system, in their efforts to produce a warmth upon the surface. Bottles or jugs of hot water, heat- ed bricks, sinapisms, Cayenne pepper, etc., should be applied to the feet and legs, until proper warmth be restored. The bowels should be freely opened, but not violently purged; for this purpose, cathartic medicine should be given imme- diately after bleeding, followed up in three hours by another dose, if it do not operate previous to the expiration of that time. During the whole disease, the bowels should be kept open by mild purgatives or injections; for purging freely is uniformly hurtful, unless on the decline of the disease, and after the liver has begun to secrete large quantities of bile, which requires to be carried off. The mildest drinks should be given during the attempt at cure, and those a little tepid. Ice may be swallowed in small portions, when it can be pro- cured; also, gum-arabic water, barley water, slippery-elm bark tea, linseed tea, etc. Drinks should be given in small quantities at a time, lest the stomach reject them. If there be much sickness at the stomach, attended by much tenderness upon pressure, the epigastrium should be leeched or cupped; and this may be followed by a blister, if the nausea or vomiting continue. Should the headache be great after due depletion from the arm, the temporal artery may be opened, or leeches or cups be applied to the temples, behind the ears, and to the back of the neck. Under these circumstances, if the feet be cold, they should be placed in hot water, with which is min- gled a quantity of the flour of mustard, and the feet suffered to remain in it for fifteen or twenty minutes. This may be 6S DISEASE AND ITS TREATMENT. repeated, pro re nata. Fresh air ought to be admitted into the room; bed clothes and body linen changed as often as practicable; light excluded, and noise prohibited. Stimulants ought not, in large quantities, to be taken into the stomach, which will augment the danger, while bleeding only dimin- ishes the power of reaction. In the first stages of yellow Aver, where recourse is had to internal stimulants, the cases are almost uniformly fatal; whereas bleeding, even when in- judiciously employed, only depresses the system, which may recover by the aid of external stimuli, and the case is not so desperate, as when stimuli have been thrown into the sto- mach during the state of active inflammation. In the case, however, under consideration, it js only the abuse of the pro- per remedy; for if the abstraction of blood be judiciously made in this state of the system, the system, instead of becoming prostrate, will react promptly; for the pulse, in the beginning of this disease is in a state of depression, as has already been explained, and not of absolute weakness; for there have been cases of recovery, as already stated, after spontaneous hemorr- hage from various parts of the body, but when the abstrac- tion of blood from the general system, by the lancet, would certainly have proved fatal. Nausea and vomiting are trouble- some conditions of the stomach, and its relief should be at- tempted by leeching, cupping, and blistering, over its region, by Seltzer water, the effervescing draught, lime water, milk, etc., but rarely in the beginning of the disease by stimulants. After decided marks of debility, clove tea, mint tea, or strong coffee, with mustard to the epigastrium, may be tried. Where the black vomit has come on, the spirit of turpentine, with the oil of cinnamon, has been of permanent benefit. Hic- cough is sometimes extremely distressing in this complaint. Camphor, in doses of from five to ten grains, will sometimes relieve it. Should it offend the stomach, it may be given very advantageously in a gill of rich flaxseed tea, and thin starch, or mucilage, of gum arabic as an enema. The utmost attention must be constantly paid to the patient, by the nurse- he should have fresh air, constant and frequent renewal of fresh, clean linen and bed clothes." YELLOW FEVER. 69 The preceding quotation embraces the most approved treat- ment of yellow fever, as adopted by the ablest physicians in the West Indies, and the United States. It appears obvious that the important objects to be attained by the treatment laid down by these physicians, are— 1st. To reduce the general inflammatory symptoms by an antiphlogistic treatment. 2d. To reduce the inflammation and paroxysms of the epigastric region, by the abstraction of blood: and also to relieve the arterial system, and take down the excess of ac- tion at the heart, by the same process, or by cupping and leeching. 3d. To cause the liver to perform its usual office of secret- ing the bile, by the application of leeches and blisters. 4th. To arrest the determination of inflammation to the head, by a resort to cold applications thereto. 5th. To keep the bowels free and active, by cathartics and injections. The recommendations for the relief of black vomit, hic- cough, and for determining the heat to the surface and ex- tremities, are such as have generally proven successful. Treatment by our external remedies: 1st. To reduce the general inflammatory symptoms, we apply our Fever Liniment in the same manner as we do in bilious, typhus, and congestive fevers, with this difference, that we make a more full and frequent application, and in producing a powerful perspiration for the first and perhaps the second time. We give but about one half the quantity of Diaphoretic Drops, that are administered in other cases. This treatment will cause a free circulation of the blood through the system, and at the same time eject large quanti- ties of morbific matter, through the perspirable pores. The tonics contained in the Liniment which has entered the cuta- neous absorbing pores, will powerfully sustain the patient, through the sweating process; and the inflammation measura- bly subsides at the same time, by the final application. Here it may be observed that the patient is much relieved from 70 DISEASE AND ITS TREATMENT. distress; a relief so obvious that his own confidence in this mode of treatment will be considerably strengthened. This treatment is more sure and safe than the antiphlogis- tic, which, though it may afford temporary relief, still leaves the patient burthened, and liable to contend with the disease unconquered. He is by weakness, less able to grapple with the second paroxysm than the first, while through the appli- cation of our remedies he has not only parted with a share of the disease, but is strengthened and made better able to con- tend with the second paroxysm, than with the first. 2d. To relieve the great distress in the epigastric region; to regulate the disorder of the arterial system, and to diminish the excess of action at the heart; we apply over these regions the same Liniment in plasters, upon which we place bottles of hot water, or bags of hot hops wet in vinegar, the object of which is to produce a more speedy entrance of the Lini- ment into the system. This treatment creates a powerful action in the organs affected, and permanent relief is to a cer- tain extent, the result. There is no uncertainty in adopting this course; whereas it is acknowledged that nothing more than temporary relief is to be expected by the abstraction of blood; and farther, if bleeding be neglected or not performed at the proper moment, much injury to the patient is the result. It would seem to be absolutely necessary that the physician be present at the proper time for letting blood, and that he should be so well skilled in the disease as to judge with pre- cision, in order to relieve the patient from a returning parox- ysm. He should also be enabled to determine the quantity to be drawn at each bleeding. Unless all these conditions be complied with, the patient suffers injury instead of benefit. Another and a more serious difficulty presents itself in this mode of treatment. Though the patient by the abstraction of blood for the moment find relief; still the disease remains unconquered, and by the debilitating process of blood letting, the patient is less able to sustain the accumulated load with which the system becomes burthened, and nature, unassisted is compelled into an unequal contest. This is not the case YELLOW FEVER. 71 when our remedies are applied; for they impart to her strength to unburthen herself of the disease. 3d. To enable the liver to perform its secretory office, we apply a plaster of Stimulating Liniment over the region of that organ, to which warmth may be added to render the Lin- iment more quickly active. By this process, the torpidity of the liver is removed; bile is secreted; and the bowels more readily perform their office. By this treatment much advan- tage is gained over that of leeching and blistering; because the effects intended to be produced by the latter practice, are thus more readily obtained and more permanently secured. It is not contended that any thing more than temporary relief can be expected from leeching and blistering, and that only after a considerable lapse of time; whereas, by our mode of treatment, relief is obtained at once. In every instance of torpidity of the liver, or of any affection of that organ, we have been enabled to effect relief by our external remedies. 4th. We arrest the determination of inflammation to the head, by an application of our Stimulating Liniment, in the same manner as we have frequently done in cases of hydro- cephalus. Let the Liniment be applied to the top and back part of the head, and behind the ears, etc.—repeat such appli- cation as often as once in two or three hours. We also apply the same Liniment to the bottom of the feet. This treatment gives action to the organs affected, and in the course of three or four hours, relief will be obtained. We have by these means always succeeded in arresting inflammation, better than those who have made cold applications. In the one case, ac- tion is imparted, and the cause removed; in the other a tor- pid state of the organs is the result, and the disease remains unsubdued. 5th. Let the Liniment be freely and often applied over the abdominal region, which in a great measure will relieve the torpidity of the bowels; so much so that gentle physic or occasional injections will generally enable the bowels to per- form their office. We are opposed to administering large doses of strong 72 DISEASE AND ITS TREATMENT. medicine internally, especially at the commencement of the attack. It is far better to rely on the external applications, as there can be no danger in them, be they ever so abundant. The Liniment passes into the system in small portions, through the cutaneous absorbing pores. Sometimes we have mixed six or eight drops of Croton oil with one eighth of an ounce of Liniment, in order to move the bowels. This is safer than strong doses of physic internally given. In the treatment of yellow fever our great object is to relieve the system of the worst features of this disease, by producing a speedy action of all the circulating fluids of the body. In some cases, this free circulation is hot easily obtained, owing to various causes, but generally in consequence of the morbid state of the system. When this is the case, much benefit may be derived from a use of the saline bath. Let the patient be immersed in as hot a bath as he can bear, and apply the flesh brush freely to all parts of the body; by so doing, the pores are opened, and the absorbents will more readily receive the Liniment; for let it be remembered that the quickness of re- lief is just in proportion to the rapidity with which the Lini- ment is introduced into the system. After the disease is overcome, the patient is invigorated, and less liable to attacks of chronic complaints than those who are treated according to the usual practice. There are no lingering, wandering pains; no remnants of the disease lurking in the system; no nervous affections or hectic cough. The system is invigorated; the stomach performs its healthy action, the bowels are regular and the patient may look forward to the cheering prospect of continued health. SPOTTED FEVER. An epidemic disease now generally recognized by the name of spotted fever, prevailed extensively in many parts of New-England, and in some parts of several other of the American States, at different times between the years 1S06 SPOTTED FEVER. 7£ and 1815. A few cases of the disease occurred at Medfield, Massachusetts, about thirty miles south-west of Boston, in March, 1S06. The number was small, however, not exceed- ing twenty, and the disorder did not so extend itself as to at- tract general attention until the following year. In March and April, 1807, it appeared in Hartford, Connecticut, and in several other places on the Connecticut river; and also in Williamstown, in the north-west part of Massachusetts, and the Green mountain range. It disappeared during the summer, but returned the following winter, visiting, in some instances, the same pkces, besides many others in their neigh- borhood, and in similar situations, and also attacking other and detached parts of New-England. The disease followed a similar course for several succeeding years. It disappeared during the summer, and returned in winter, and for several years, until 1813, it became each year more extensive and more destructive. In some of these years, it also prevailed extensively in the interior of the States of New-York and Pennsylvania. In 1812, the troops of the United States army suffered by it severely, at various places in New-York and Vermont. After 1813, the disease rapidly diminished, al- though it still continued destructive, especially in some parts of Maine. It finally ceased in the spring of 1815. The last place visited by it, so far as our information extends, was Ber- wick, in Maine. There have indeed been some occasional reports of the prevalence of a similar disease, at different times since that period; but it may well be doubted whether any of them actually refer to the true spotted fever, as it pre- vailed from 1807 to 1815. This concise sketch of the progress of the epidemic shows that it prevailed much less in summer than in winter. In fact, it was only during a part of the colder season of the year, that the disease raged most severely. Unlike the ordinary typhus fever of our climate, it was much less frequent through the autumn and the earlier part of winter than during the latter months of winter, and the first months of spring. It is worthy of remark, that the disease, in a great measure, avoided the 10 74 DISEASE AND ITS TREATMENT. large towns on the sea coast. Although it pervaded at dif- ferent times, almost the whole of the interior of New-Eng- land, Boston and the other large towns were only slightly affected by it. In the interior also, the epidemic was not more prevalent, perhaps even less so, in the larger and more crowded villages, than in the less populous places. This is the more remarkable, since those persons whose modes of life render them peculiarly susceptible to disease of every kind, are more frequently collected in large towns and vil- lages. But this epidemic seemed scarcely to regard peculiar susceptibilities of any kind. The man, whose constitution was exhausted by excesses, unavoidably yielded more readily when attacked, and fell a more certain victim, than the man of temperance and regular habits. But it does not appear that such were more frequently attacked than others. On the contrary, the disease seemed rather to select the healthy and vigorous. Although in its range, it embraced persons in every period of life from childhood to old age, yet the pro- portion of cases and of deaths was much greater among adults of mature age, of firm health, and of habits every way cal- culated to resist ordinary disease. In many an agricultural town in New-England, the correct, virtuous, and middle aged heads of families, were swept off in such numbers as to leave a mournful vacancy in the general aspect of the community, which is even now observable, after the space of twenty years, in the absence of old men from congregations assembled for their weekly public worship. Of the extent of mortality produced by spotted fever, there are no means of obtaining accurate knowledge. Except in the larger towns, no returns are preserved of the number of deaths, or their causes. There are, therefore, no data upon which to found an estimate of the destruction of life, caused by this epidemic. It was, however very great, and from the character and relative station of many of its victims, pecu- liarly afflicting. The visitation too, was sudden, and, there- fore, produced the greater alarm and distress. In some in- stances, the disease visited a place twice, or even three times; SPOTTED FEVER. 75 but, in general, its work was accomplished in a single visita- tion of a few weeks duration. Dr. Gallup remarks of the epidemic in Vermont, that -'There are but few towns whose surviving inhabitants will not long, with grief, remember the winter of 1812-13, for the loss of twenty, forty, or eighty of their most valuable citizens—most valuable to society, on account of their being in the prime of life." Of the causes of spotted fever, no satisfactory account can be given. There was nothing in the habits of the disease, or the manner in which it proceeded from place to place, to counte- nance the theory of contagion; and such a theory we believe has never been suggested. It is difficult to reconcile the phe- nomena of this disease, to any of the other theories by which the progress of epidemics has been explained. If we attri- bute it to some secret atmospheric influence, it is not easy to account for their regular and fitful manner, in which it lio-hted upon detached and distant places almost at the same moment, while intermediate places were passed by for the time, only to be the subjects of a future visitation. It is still more im- probable that exhalations from the surface of the earth could have been its cause, for the favorite season of the disease was fast locked in frost. For a time many physicians were in- clined to suppose that ergot in the rye, which is much used in New-England, might have contributed to produce the dis- ease. But it has never been shown that ergot was more abundant in those years in which the epidemic prevailed, than in others; and what is still more conclusive, the disease was not confined to those districts, in which rye was used for bread. We must, therefore, regard the peculiar causes of spotted fever, as altogether unknown. In the description of the disease, we must necessarily be very brief. There were two leading forms of it. One was a simple fever of a peculiar character. The other was compli- cated by local inflammation, but it still retained the same gene- ral character as the other. The more simple form began, like most other fevers, with coldness, not generally with distinct shivering; pain in the head and back, and especially in the 76 DISEASE AND ITS TREATMENT. limbs; prostration of strength, etc. In the milder cases, this was followed, as in other fevers, with some degree of reaction, manifested by heat, and afterwards by sweating; but, unless aided by proper remedies, the reaction was very imperfect; the coldness soon returned, with a peculiar want of action over the whole system. The surface of the body lost its pe- culiar elasticity, and had in its stead a torpid, half cedematous, doughy feeling. Near the close of life, it was covered with a profuse perspiration. The stomach early became irritable, and rejected whatever was put into it, though without much vomiting of any thing else. The prostration increased, and was accompanied by violent pains in the back or limbs, which frequently changed from place to place, but without spasms of any kind. In many cases, delirium came on very early. In most instances, as the strength of the patient failed, the mind became obscured, and he died comatose. In the more severe form of the disease, this comatose state followed the first at- tack, without any intervention of a stage of reaction: the patient became insensible, and died in a few hours. It was generally in this severe form that the spots, or petechia, ap- peared, which gave the name of spotted fever to the epidemic. They were not, however, confined to the more violent, or to the fatal cases, but were occasionally found in those which were comparatively mild. Neither, on the Other hand, were they, by any means, general in the severer cases. In the ear- lier periods of the epidemic, they were much more common than towards the close of its progress. When they did ap- pear, the spots were generally small blotches, caused by blood extravasated into the cellular membrane under the skin, of a dark purple color. In many other cases, there was a slight eruption of a very different character, which seemed to be caused by the excited state of the skin, where the diaphoretic and stimulating mode of treatment was carried to a great ex- tent. About the beginning of the year 1812, the spotted fever first began to assume a new form, in many cases, by be- coming complicated with. some local inflammation. This inflammation was sometimes in the throat, producing a species SPOTTED FEVER. 77 of cynanche; but its more common seat was in some one or more of the textures of the lungs. The fever, however, still retained the same general character as before; and in most of the places where this form of the disease prevailed, frequent cases of the more simple form were intermingled with it. The cases with inflammation were ushered in, rather more frequently than the others, with a distinct chill; and this was oftener, perhaps, followed by a distinct reaction; but the gen- eral disease did not in these cases, any more than in the others, retain an inflammatory character. On the contrary, it ran speedily into a state of great depression; and when death en- sued, it seemed to be less from the influence of the pulmonic symptoms, than from the violence of the general disease. There was pain in the chest, with cough, and bloody expec- toration; but these symptoms, although sometimes severe in the commencement of the disease, rarely retained their promi- nence so long as to appear to exert a very important influence upon its course, or to demand much consideration in the treatment, beyond what was necessary to give relief to the symptoms themselves. There were many other varieties in the modifications of the spotted fever, which the limits of this sketch will not permit us to notice; for it assumed a greater diversity of forms and appearances than most diseases. It was always sudden and abrupt in its attack, as we have here described it, but sometimes crept on silently, slowly convert- ing a slight indisposition into a severe, and often fatal disor- der. In whatever form it appeared, however, it exhibited the same general character of great prostration and debility. Little is known of its pathological character, except what has been learned by inferences from its description and history. Only a few examinations after death, were made. The state of public feeling throughout the interior of New England was much less favorable to such examinations, twenty years ago, than it is now; and the medical profession were then much less accustomed to press the importance of this mode of investigation, than at present. Such examinations as were made, have done little to enlighten us in regard to the essen- 7S DISEASE AND ITS TREATMENT. tial character of the disease. And had they been much more numerous, the result would probably have been no more con- clusive, than that of similar observations in respect to the nature of fever in general. The blood was found to remain fluid for some hours after death. It consequently flowed to the depending parts, giving a dark color to the skin in those parts, which was often mistaken by careless observers for putrefaction. But putrefaction did not begin early after death. The vessels of the brain, as might be expected from the coma- tose state which preceded most of the deaths, were found to be turgid with blood, and there was more or less effusion of serum into the ventricles, and sometimes of lymph under the arachnoid. In the chest, the heart sometimes exhibited marks of disease, its vessels being peculiarly injected with blood. The lungs, in the cases of simple spotted fever, were healthy. We have seen few accounts of dissections in the pneumonic form of the disease. In some cases ulcerations, of a peculiar character, with black, gangrenous edges, were found in the pleura of the lungs, extending deep into the substance of the organ. This appearance can hardly have existed, except in the severest form of pneumonic affection. But we do not remember any description of marks of inflammation in the lungs, which did not involve the serous membrane, although, from the symptoms, it can hardly be doubted that many such cases existed. The abdominal viscera were generally healthy. The gall bladder, and the urinary bladder, were filled with their appropriate fluids, showing that the secretions had been carried on until death. The result of our pathological obser- vations is, that this disease was a fever, having a peculiar ten- dency to run rapidly into a state of great prostration and debility, and often more or less complicated with local inflam- mation of an erysipelatous character. The practice which had been previously applied to ordinary fevers, was so entirely unsuccessful in the treatment of spotted fever, that many of the practitioners, on whom the manage- ment of the disease at first devolved, seem early to have lost all confidence, not only in such a course of practice, but also SPOTTED FEVER. 79 in the resources of professional skill and science, and for a time to have abandoned themselves and their patients to em- pirical experiments. A respectable writer gives the credit to a worthy matron, of the first discovery of a successful treat- ment. This consisted in exciting a profuse perspiration, by drinking large quantities of a decoction of the leaves and twigs of the ground hemlock, or dwarf yew, aided by a rude sort of vapor bath, made by boiling billets of wood (of hem- lock, if to be obtained), and laying them, wrapped in cloths, in bed with the patient, who was at the same time to be kept highly stimulated with brandy, and other diffusible stimulants. But the more judicious and scientific part of the profession, were not long in adapting their treatment to the true state of the disease. Adopting a hint, perhaps, from the effects of the empirical sweating and stimulating, which soon became common, they were able to pursue a course of diaphoretics and stimulants which, while avoiding the dangers of empiri- cal excess, was eminently successful in arresting the fatal tendency of the disease. Such diaphoretics were selected, as, while they act promptly and surely, have the least tendency to induce debility. A moist heat, applied externally, added much to the efficacy of internal diaphoretics. A combination of ipecacuanha, opium, and camphor, with sometimes the addition of calomel, was much used, and with the best effects. It was necessary that a gentle diaphoresis should be constantly preserved, always with great care, avoiding profuse sweating. The true measure of the use of stimulants, was the preserva- tion of a healthful temperature and an equable pulse. In some cases, the tendency to coldness and prostration was so great, that large quantities of the most powerful stimulants were necessary. Brandy in hot water, tincture of cinnamon, tincture of opium, with tinctures of peppermint and lavender, were among the best; and these were to be used, not so much in reference to the quantities given, as the effects produced. Very early in the disease, almost as soon as a diaphoresis was established, tonics of a more permanent character were em- ployed. The cinchona, in its different modes of administra- 80 DISEASE AND ITS TREATMENT. tion, was chiefly relied on. A favorite mode of using it, by many physicians, was in a fermented decoction, with orange peel and serpentaria. A nutricious and rather stimulating liquid diet was also prescribed quite early in the disease. Emetics were avoided, or used only when there were mani- fest symptoms of decided derangement of the stomach; and cathartics were only used to remove costiveness, and then none but the mildest laxatives were to be administered. In the pulmonic form of the disease, blisters and expectorants were added to the other means. It was sometimes necessary, on account of the cough, etc., to defer a little the use of cinchona and other tonics; but this did not often happen, and it never appeared safe to wait for a decided convalescence before re- sorting to them. This is a mere outline of the treatment adopted by a large proportion of the most successful practitioners, in this singular and formidable disease. It of course admitted and required great diversity in its application to the many varieties of form and symptoms, which the disease assumed at different places, and in the several cases. There were a few physicians, how- ever, who objected to such a stimulating practice, and insisted upon the necessity of blood letting and other evacuents, and who still contend that an anti-phlogistic course of treatment was the most successful. It may be said, indeed, that the prostration and debility must have been produced by some active disease, and if that disease could be arrested by early bleeding and other means, much of the prostration would be prevented. But, however true this may be in general, in the present instance, the good effects which generally fol- lowed a judicious course of stimulants, sufficiently showed that no such disorganization was produced by the disease, which was supposed to cause the debility, as to render it un- safe to trust to them to remove it. If the bleeding recom- mended had failed to prevent the sinking by arresting the disease, it must have increased the exhaustion, and conse- quently added to the difficulty of the cure. Moreover, to perceive accurately when it would be liable to do this, would SPOTTED FEVER. SI have required a nicety of discrimination greater than belongs to most medical practitioners, if indeed, it can ever be ob- tained. The results of the treatment were very various at different places. In many places, the disease, though violent and severe, yielded to remedies with a docility truly remark- able. At the same time, it required unceasing vigilance and care to prevent fatal relapses. In such places, most of the deaths seemed to result more from accidental imprudences or neglect, than from the incurable nature of the disease itself. In other places, the disease was speedily fatal to a large pro- portion of those attacked. In some small districts, twenty or thirty died in rapid succession, before any recovered. Much of this inequality is doubtless to be attributed to differences in the virulence of the epidemic itself. But there are many facts which go to show, that something must be ascribed to diversities of treatment. The comparison here intended is not between the diaphoretic and stimulating practice on the one hand, and the antiphlogistic on the other, so much as be- tween each of these systems, and an awkward attempt to engraft one or the other of them upon a routine of earlier days, which many men found it difficult to abandon. To our minds the stimulating treatment, properly regulated, was in- comparably preferable to the bleeding; but either was immea- surably better than the hesitating, inefficient practice to which we have alluded. If it were proper to go into details, many examples might be adduced, in which a change of practice was followed by a change of results, in the same neighbor- hood, and often in the same families, so immediate and so striking as to render it difficult to attribute the difference to any thing but the change of treatment. The principal treatises on spotted fever, besides various papers in the several medical journals of the time, are North on Spotted Fever; Strong on ditto; Report of a committee of the Massachusetts Medical Society, published in the second volume of that Society's communications; Gallop on the Epidemics of Vermont; and Hale on the Spotted Fever in Gardiner. 11 S2 DISEASE AND ITS TREATMENT. Remark.—Whoever reads the foregoing article on spotted fever, and also on the practice we have adopted in fevers gen- erally, will readily discover that more than twenty years ago the most successful practitioners in the United States, in that desperate predicament in which they were placed, adopted all of the essential principles of our system. The history of spotted fever is truly appalling! In the usual antiphlogistic treatment, almost all who were attacked fell victims to the disease; and so terrific had this fell destroyer become that all stood aghast! It is acknowledged that the physician aban- doned his patient in despair; that he also lost all confidence in the science of medicine—until an aged matron discovered the means of arresting the direful march of death. She adopted the stimulating and diaphoretic practice. She caused large blocks of wood to be boiled and made hot, and laid them around the patient, which soon produced a proper per- spiration. As a natural consequence, a reaction took place in the system. She gave large portions of brandy as a stim- ulant, which prevented the patient from sinking under the sweating process. The physicians took a hint from the re- sult of this treatment and attempted to improve it. But how much their philosophical ingenuity exceeded that of the aged matron, the light which twenty years have shed upon the sub- ject will show. Suffice it to say that they adopted all of the essential principles in this desperate disease, for which we now contend; and the history given by these same physi- cians shew conclusively that they 'adopted it with success. The difference arises only in the therapeutical agents which they used, and the agents of which our concentrated remedies are compounded, to produce the same effect. With any medical man who has become acquainted with our remedies, we are willing to trust the decision. Here let it be remembered, however, that one of the most fatal epidemic fevers that ever visited any country, is acknowledged to have been successfully treated, without the exhibition of emetics or blood-letting. SCARLET FEVER—CHOLERA. 83 SCARLET FEVER. Scarlet Fever (Scarlatina); a contagious fever, char- acterized by a scarlet colored eruption, in patches, which, after three or four days, fall off in scales. Some have asserted that scarlatina never attacks the same person a second time; but more extensive observation has falsified this opinion. It seizes persons of all ages; but children and young persons are most subject to it. It appears at all seasons of the year, but is more frequently met with towards the end of autumn, or beginning of winter, at which time it very often becomes a prevalent epidemic. Scarlatina, in its inflammatory form, is not usually attended with danger, although a considerable degree of delirium, in some instances, prevails for a day or two; but when it partakes much of the malignant character, (scarlatina anginosa,) or degenerates into typhus pu- trida, which it is apt to do, it often proves fatal. TREATMENT. It is truly astonishing, the readiness and certainty with which our remedies for fever overcome this complaint. The cases of scarlet fever which have heretofore been thus treated, have uniformly terminated successfully. But very little alter- ation from our usual treatment of fever, is required. If, however, delirium supervene, a very free application of our Nerve Liniment to the head, and of the Stimulating Liniment to the feet, will be of much service. The patient has generally been relieved in one day, and it is not unfrequent for all appearance of disease to be over- come in forty-eight hours. CHOLERA. Cholera, Cholera Morbus, Cholera Asphyxia, Cholera Maligna, Cholera Epidemica, Epidemic Cholera Fever. All these names have been applied by different observers, to 84 DISEASE AND ITS TREATMENT. a formidable disease, which has, for the first time, been re- cently known to be extensively epidemic in the world, and whose origin and ravages will be reckoned among the most remarkable events of the present century. Long prior to the appearance of the present epidemic in the Delta of the Gan- ges, in 1817, and its subsequent diffusion over so large a por- tion of the globe, extensive and destructive visitations of Cholera had been noticed by various writers. One of them, we learn, occurred in Europe at the close of the seventh cen- tury; but most of them originated in the East, and limited their devastations to that quarter of the world. The indefati- gable Mr. Scott has quoted, from the Madras Courier of 1819, a letter which suggests the opinion that a description—though certainly a very obscure one—of disease resembling that which has prevailed, is to be found in a Hindoo work of great antiquity, and cites instances of the epidemic prevalence, and great fatality of cholera, from the time of Bontius, in 1629, to the present century; but the description of these epidemic visitations has not reached us in so detailed a form as to enable us to judge correctly of their identity with what has been recently observed. Enough, however, may be ascertained, to prevent our denying its identity in some instances. Indeed, it is impossible not to be struck with the resemblance which certain of the more accurately reported of these examples bear, to the disease now existing. But this much seems cer- tain, that, however cases may, in previous visitations, have resembled in character the prevailing disease, no other re- corded cholera epidemic has equaled this, in the wideness of its diffusion and extent of its ravages, or has preserved its character and intensity so little influenced by climate and temperature. The question of the identity of the disease which has prevailed in Great Britain, on the continent, and in the United States, with that which ravaged Hindostan, having been settled in the affirmative, at least as regards cer- tain of their most important practical points, by the various respectable physicians who have witnessed both diseases, we may assume that much of the valuable information transmit- CHOLERA. 85 ted to us from India, respecting the nature and treatment of the malady which raged there, is applicable to that which has ravaged Europe and America. Symptoms of Cholera in India.—The disease generally makes its attack in the night, or towards morning, with such excessive vomiting, that the whole contents of the stomach appear to be discharged; and, nearly at the same time, the bowels are copiously emptied, as though all the solid matters in the intestinal canal were evacuated. In some cases, a wa- tery purging precedes the vomiting by some hours; but, they more frequently occur simultaneously. After the first copious discharge, the patient experiences a distressing feeling of ex- haustion, and faintness, with ringing in the ears, and giddi- ness. The subsequent discharges from the stomach, and those from the bowels, do not differ in appearance from each other, excepting so far as the matters ejected from the stomach may be tinged by medicine, or other foreign ingesta; they are in general watery, colorless, and inodorous, and are compared in their appearance to barley broth, or more frequently to rice- water. Sometimes they are like milk, occasionally yellowish, greenish, like muddy water, or yeast; but the congee stools, as they are emphatically termed, which consist of albuminous flakes floating in serum, or discharges of pure serum, are of the most frequent occurrence. The ejections sometimes take place without effort or uneasiness, but occasionally very forci- bly, with simultaneous vomiting, spasms, and sinking of the pulse. The violent action of the alimentary canal is not of long continuance, the powers of the system not being able to support it: hence the vomiting and purging cease some hours before deaths but, in some cases, a discharge of serum takes place from the rectum, on any movement of the body, until the fatal termination. In most cases, some time after the com- mencement of this affection of the intestinal tube, but, in others, previously to it, spasmodic contractions of the mus- cles of the fingers and toes, are felt; and these affections gra- dually extend along the limbs to the trunk. The spasms are imperfectly clonic, or convulsive, with unfrequent relaxations; S6 DISEASE AND ITS TREATMENT. they are attended with great pain, and leave, for some days afterwards, a degree of stiffness in the muscles. The pulse is, from the first, small, weak, and indurated; and, after a cer- tain interval, but especially on the accession of spasms, or severe vomiting, it sinks suddenly, so as to be speedily im- perceptible in the external parts. The length of time a per- son will live in this pulseless state, is remarkable. In a case related by Dr. Kcllett, the pulse was gone within three hours from the attack, )Tet the man lived twenty-two hours in that state. On the cessation of spasms and vomiting, and some- times apparently from the exhibition of remedies, the pulse will return in the extremities for a short time, and again cease. The skin is cold from the commencement of the disease, and, as it advances, becomes gradually colder, and is covered with profuse sweat, or a clammy moisture. The state of its circu- lation, and its insensibility, is sometimes strongly denoted by the following circumstances: Leeches will not draw blood from it; blisters, and other vesicatories, will not act; and even the mineral acids, and boiling water, produce no effect; and some patients are not even sensible of their application. In Europeans, the color of the surface is often livid; the lips and nails present a blue tint; and the skin of the feet and hands becomes corrugated, and exhibits a sodden appearance, as after long immersion in hot water. With these symptoms co-exist violent pain of the intestines, with a sensation of writhing and twisting there; heartburn, which the sufferer compares to a fire consuming his entrails; excessive thirst; anxiety, with inexpressible uneasiness about the praecordia; hiccough; jactitation; and, notwithstanding the actual coldness of the surface, and even of internal parts which are accessible to the touch, (the tongue, for instance,) a sense of heat which impels the patient incessantly to throw off the bed-clothes. The breathing is much affected, being performed either more slowly than usual, (sometimes, for instance, in the advanced stage, only at the rate of seven respirations in a minute,) or the inspirations are short and sudden, with violent pain from spasm of the diaphragm; the voice being feeble, hollow, CHOLERA. 87 hoarse, and interrupted. The eyes are sunk in their orbits; the corneal fluid, the conjunctivae, frequently suffused with blood; the features collapsed; and the whole countenance wears a cadaverous aspect. The secretions (those of the skin and intestines excepted) are generally suspended. The func- tions of the mind are undisturbed, almost to the very last moment of existence. The approach of recovery is denoted by the rising of the pulse, return of heat to the surface, in- clination to natural sleep, diminution or cessation of vomiting, purging, and spasms; and, after an interval, the reappearance of bilious stools, urine, and saliva. Regarding the preceding as a picture of the general type of a disease rather variable in its character, we shall proceed to relate the more striking deviations from the ordinary forms which were observed in India. Instead of an exceedingly depressed state, there was a marked excitement, with a hot, dry skin, and, in several instances, a pulse of considerable force, throughout a great part of the course of the disease. This, in some cases, arose from the early application of stim- ulants; but in others it appeared to be an essential part of the disorder. These cases yielded most certainly and readily to treatment; and hence many of them have been subdued, with- out the occurrence of sinking or debility. It was at first a matter of doubt, whether this description of disorder really belonged to the epidemic; but that it did so, was placed beyond all question, by some of the more prostrated cases degenerat- ing into the ordinary low form. The most fatal variety of the disease, was denoted by the slightness of commotion in the system. There was no vomiting; hardly any purging; perhaps there were only one or two stools, with no percepti- ble spasm; no pain of any kind; a mortal coldness, with a check of circulation from the beginning; and the patient died without a struggle, within three or four hours. Several in- stances were heard of, at Hoobly and other places, of natives being struck with the disease while walking in the open air, and who, having fallen down, retched a little, complained of vertigo, deafness and blindness, and expired in a few minutes. 8S DISEASE AND ITS TREATMENT. Mr. Scott informs us, that this most deadly form of the dis- ease frequently manifested itself in local epidemic visitations, which were often observed in India—all the cases occurring at the same time in a given district, partaking of the same peculiarity of character. The collapsed form of disease, first described, is that which has been most frequently observed. In fatal cases, its dura- tion varies from four to eight hours; while in those which terminate favorably, {a result often apparently due to early medical assistance,) the patient may be restored to perfect convalescence, in a period ranging between twenty-four and forty-eight hours. But, in many cases, considerable disturb- ance of the system intervenes between the period of collapse and restoration to health, or this disturbance may itself cause death. The Indian reporters mention two forms of this dis- order. In the one, with some excitement of the system, the bowels continue to discharge, for many days, first brown and watery, then dark, black, pitchy stools, sometimes with blood, and peculiar pain in the bowels, particularly in the rectum. The other, a distinct febrile form, we shall describe in the language of the Bengal Report:—'-'The fever, which almost invariably attends this second stage of the disease, (in Euro- peans,) partook much of the nature of the common bilious attacks of these latitudes. There was a hot, dry skin, with a foul, deeply furred tongue, parched mouth, thirst, sick sto- mach, restlessness, watchfulness, and quick, variable pulse, sometimes with delirium and stupor, and at others, marked af- fections of the brain. Generally, when the disorder proved fatal in this stage, the tongue, from being cream colored, be- came brown, and sometimes black, hard, and more deeply furred; the teeth and lips were covered with sordes; the state of the skin varied, chills alternating with heats; the pulse became extremely quick, weak, and tremulous; hiccough, catching of the breath, great restlessness, and-deep moaning, succeeded; and the patient soon sunk, incoherent and insen- sible, under the debilitating effects of low, nervous fever, and frequent, dark, tarry, alvine discharges." A consecutive CHOLERA. 89 fever, similar to this, we learn from Doctors Russell and Barry, is of more frequent occurrence in Russia than in India. The following description we owe to these gentlemen:— "After the blue, cold period has lasted from twelve, twenty- four, seldom to forty-eight hours, or upwards, the pulse and external heat begin gradually to return; headache is complain- ed of, with noise in the ears; the tongue becomes more load- ed, redder at the tip and edges, and also drier. High colored urine is passed, with pain, and in small quantities; the pupil is often dilated; soreness is felt, on pressure, over the liver, Stomach and belly. In short, the patient is laboring under a continual fever, not to be distinguished from ordinary fever. A profuse perspiration may come on from the second or third day, and leave the sufferer convalescent; but much more fre- quently, the quickness of the pulse and heat of the skin con- tinue; the tongue becomes brown and parched; the eyes are suffused and drowsy; there is a dull flush, with stupor and heaviness, about the countenance, much resembling typhus; dark sordes collect about the lips and teeth; sometimes the patient is pale, squalid, and low, with pulse and heat below natural; but with the typhus stupor, delirium supervenes, and death takes place from the fourth to the eighth day, or even later, in the very individual, too, whom the most assiduous attention had barely saved in the first or cold stage. To give a notion of the importance and danger of cholera fever, a most intelligent physician, Doctor Reimer, informs us, that of twenty cases treated under his own eyes, who fell victims to the disease, seven died in the cold stage, and thirteen in the consecutive fever." The same gentlemen state, as the result of their observa- tions, that the following are the points of difference between the European epidemic and that of India:—"First, the evacu- ations, both upwards and downwards, seem to have been much more profuse and ungovernable in the India than in the present cholera, though the character of the evacuations are exactly the same. Secondly, restoration to health from the cold stage, without passing through consecutive fever of 12 90 DISEASE AND ITS TREATMENT. any kind, was by far more frequent in India than in Peters- burgh; nor did the consecutive fevCr then assume a typhoid type. Thirdly, the proportion of deaths in the cold stage, compared with those in the hot, was far greater in India ac- cording to Doctor Russel's experience, than in Petersburgh. Fourthly, the number of medical men and hospital attendants attacked with cholera during the present epidemic, in propor- tion to the whole employed, and to other classes in society, has been beyond all comparison greater in Petersburgh than in India, under similar circumstances." Doctor Keir of Moscow, gives the following description of the consecutive, or secondary morbid state:—" A second ordeal now begins, sometimes as severe, and frequently not less fatal, though more slowly so, than the first: this is pro- bably the effect of morbid changes, which have been induced during the first stages of the disease. The appearance of the complaint is now entirely changed, insomuch that one who had not seen the patient during the first, period, or been told of the symptoms, could not possibly know he was suffering from the epidemic. I have observed the disease in this, its usual period, to assume four forms: the first, an inflammatory, or rather sub-inflammatory state of the stomach and bowels, most frequently the latter, sometimes conjoined; the second, inflammatory irritation of the lungs, with pain in the chest, cough, viscid expectoration, and fever, approaching as a criti- cal metastasis of the disease; the third, bilious or bilio-ner- vous fever, with -suppuration of the parotid glands, in one case, with axillary suppurating bubo, towards the end of the fever, an inflammatory irritation of the lungs took place, ending in vomica; and the fourth, a congestive sub-inflammatory state of the brain, and spinal cord. This last, as was natural to expect, from the nature and seat of the affection, proved by far the most dangerous and most frequent fatal form of the second period; it appears generally to supervene after the purging, vomiting, and cramps had been relieved, and the ex- ternal heat in some degree restored; the patient complained of pain in the back, between the shoulder blades, or in some CHOLERA. 91 other part of the spine, sometimes along the whole tract; he appeared sleepy to such a degree, that I was disposed to at- tribute this state, in part at least, to the effect of the opium given in the first period. But I was soon convinced that the cause of this symptom, and of others strongly characteristic of this form of the disease, namely, the filling of the vessels of the sclerotica with red blood, was a congestive sub-inflam- matory state of the brain, and of the spinal cord. This strik- ing symptom at first began to show itself in the inferior part of the globe of the eyes; it gradually increased, and little by little, reached the upper part, while the eyes turned upward, exposing the lower part gorged with blood. This state of the patient generally ended in a complete coma, and proved fatal in a few hours afterwards." Besides the various and appalling symptoms, which indicate general derangement of the action of the solids, there are appearances in the blood, drawn during the collapsed stage, showing that the fluids feel the influence of this formidable disease. These appearances are very uniformly expressed by the terms dark, black, or tarry, in regard to color, and by thick, ropy, syrupy, or semi-coagulated, in respect to con- sistence. This change in the condition of the circulating fluids is fully proved to be in the ratio of the duration of the disease; the blood, at the commencement, seeming to be nearly or al- together natural, and more or less rapidly assuming a morbid state, as the malady advances. This condition was less con- spicuous in cases of cholera ushered in by symptoms of ex- citement, than where the symptoms of excitement had oc- curred early; and in certain rare cases it was not observable at all, and the blood flowed readily from the vein; but the re- verse was the fact, both with respect to its condition and manner of flowing from the arm, in an immense majority of instances. In general, after a certain quantity of dark, thick blood had been drawn, its color became lighter, its consistence less thick, and the circulation revived, such appearances al- ways affording grounds for a proportionably favorable prog- 92 DISEASE AND ITS TREATMENT. nosis. There is some discrepancy in the accounts transmit- ted to us, of the mode in which this diseased blood coagulates. In some instances, we learn, the coagulation is rapid, whilst in others it is slow and imperfect. Reports are unanimous in declaring it deficient in summer, and destitute of the huffy coat. The latter is occasionally observed in cases attended with reaction, in which the blood is not black and thick. The discharges from patients suffering under this disease, were subject to experiment by Doctor Christie. The secretion con- sists of two substances, the one a transparant serous fluid, the other an opaque white coagulum; the former perfectly soluble in cold water, the latter quite insoluble. These matters being submitted to the reaction, the fluid part was found to be pure serum, and the coagulated portion fibrin. The secretion, threfore, as the author remarks, has a composition similar to that of blood deprived of its coloring matter; but the serum is in much larger proportion than the fibrin. Character of the Epidemic, as it appeared in Sunder- land in 1831.—Thus far, (says the English writer,) our ac- count of this formidable malady has been derived from the very valuable mass of information, with which we have been favored by our medical brethren in India, and the many in- telligent men who have witnessed its ravages on the continent of Europe. Circumstances having brought it under our own observation, we shall endeavor to convey succinctly to the reader, the results of our experience, prefaced by a few re- flections on the character and designation of the disease, which this experience has suggested to us. Were we to at- tempt a definition of epidemic cholera, the following, accord- ing to our experience, would comprise its distinctive symp- toms. After watery diarrhea, or other slight indispositions, ensue vomiting and purging of a white colorless fluid, violent cramps, great prostration, and collapse. Note.—By collapse in this definition, is meant a feebleness or almost an arrest of the circulation; the death-like appear- ance, the coldnesss which may in other diseases be observed after they have existed some time, and as the powers of life CHOLERA. 93 are passing away; but which occur in what we shall call the cold or choleric stage of the epidemic, in a short time after its commencement, as though they formed an essential part of it. The degree and early accession of this collapse, and the white discharge, are the only distinctive marks that we are aware of, between this stage of the epidemic and the or- dinary cholera, the last occurring simultaneously with the vomiting and cramps, or shortly after them. Should the pa- tient survive the last train of symptoms, a state of excitement and fever supervenes. We can convey a correct idea of the disease, only by dividing it into three stages, the incipient, the cold or choleric, and the febrile: the division accords with the character of the disease. 1st. Symptoms of the Incipient Stage.—In an immense majority of instances, diarrhea has been the prominent symp- tom of this stage. Languor and lassitude, occasionally nausea and vertigo, co-existed with the disorder of the bowels, and sometimes certain of these symptoms may have appeared without it; but its occurrence has been so common, that we have treated few cases in which it has not preceded the more formidable symptoms. On examining the discharges, if we have an opportunity of doing so shortly after the occurrence of the diarrhea, they will be observed to be foecal and bilious; but we shall find that they subsequently bear the serous char- acter of those which occur after the choleric stage is fully found: they are passed copiously, and without much griping; the feeling of debility which attends them is great, and this diarrhea is so exhausting, that we have met with patients, especially those advanced in life, in whom a considerable de- gree of collapse had occurred, with a feeble pulse, scarcely exceeding fifty, before the accession of vomiting and cramps. The natural tendency of this purging is, we believe, to pass into the choleric stage; but transition has frequently occurred shortly after some dietetic error, either as to quantity or quality of food, or after exposure to cold. The commence- ment of the purging has sometimes preceded, by several days, the accession of the choleric stage, and occasionally only by 94 DISEASE AND ITS TREATMENT. eight or ten hours; but forty-eight hours has been its mean duration, calculated for a great number of instances. We have dwelt more on this incipient stage, from a conviction, the result of considerable observation of the disease, that sub- sequent symptoms might often be prevented, and life pre- served, by early and proper treatment of the diarrhea. 2d. Symptoms of the Cold, or Choleric Stage.—Our description will be more intelligible, if we divide into two periods this very important stage, which has, in truth, given its name to the disease, and, by its fearful symptoms, has en- grossed such general attention, that the fact of its being but part of a series of changes, has been too often lost sight of. First Period.—The time of invasion has been, as in India, in a great majority of instances, from two to four o'clock in the morning. The patient is attacked with uneasiness of the stomach, occasionally amounting to pain, to which speedily succeeds vomiting of the characteristic fluid so frequently described; and, if diarrhea have preceded, which, in almost all the cases we have noticed, has been the case, a purging of the same fluid, the fcecal contents of the canal having been previously expelled. The vomiting is rarely full and effec- tual, consisting rather of unsatisfactory retchings, than of a full discharge of the contents of the stpmach; but sometimes these contents are expelled forcibly, as if squirted from a syringe. The discharges from the bowels are occasionally scanty, but much more frequently they take place copiously and forcibly. Simultaneously with the vomiting, or not un- frequently before this symptom has occurred, cramps take place; and the agony that attends them constitutes a great share of the sufferings of the patient, who incessantly entreats that friction may be applied to the parts they affect. How- ever soon our visit may be made, the pulse will generally be found to be feeble and frequent; the skin, in point of heat, below the healthy standard, the countenance Shrunk, and, if not livid, pallid; and the respiration hurried, if not checked, as it frequently is, by spasms of the diaphragm and intercostal muscles. The circulation sinks remarkably, and sometimes CHOLERA. 95 appears momentarily to cease, on every occasion of severe vomiting or spasm. Second Period.—The mean duration of the preceding varies from about eight, to twelve hours; the vomiting and spasms then either totally subside, or recur at much longer intervals, and the patient sinks into a state of extreme collapse. The pulse at the wrist is scarcely, or not at all perceptible; the surface is universally moist and cold, excepting as heat is imparted from without, for the instant the hands or other parts are exposed, they become of an icy cold- ness; blueness, if it exist at all,—but it is by no means a uni- form symptom,—is now conspicuous on the face and hands, which last have the shrunk and sodden appearance so gene- rally described; the tongue is moist, and, if not actually cold, at least cooler than natural; and the voice is of that mingled huskiness and feebleness which strikes the ear so peculiarly. In this condition there is little suffering, excepting from the sense of weight and oppression at the praecordia, of which the patient complains much; for even should, spasms occur, they are now too feeble to excite much pain; the respiration is slow; the conjunctivas, in their inferior hemisphere, are frequently injected with dark colored blood; and the insensi- bility of the stomach is so great, that the most powerful stimulants may be given and retained without the organ being apparently more sensible of their presence than if it were a lifeless pouch. The urine is suspended throughout the whole course of a choleric stage so intense as we have described it. 3d. Symptoms of the Febrile Stage.—The preceding stage, in most cases, makes a very gradual transition into the present one. After the patient has remained in a collapsed state for a considerable time, some degree of warmth will be found returning to the surface, which, for a variable period, perhaps for a couple of days, has been almost of an icy cold- ness; and the pulse is proportionally developed, being early perceptible at the wrist, generally about eighty, and soft; the vessels of the conjunctivas gradually become distended with blood; or if those of the inferior hemisphere have been so during the stage of the collapse, the distention now diffuses 96 DISEASE AND ITS TREATMENT. itself over the whole membrane; the patient, who, on his attention being roused, is perfectly sensible, complains of se- vere pain in the head, of a sense of giddiness, and that the light distresses his eyes. The tongue, in this early stage, is clean and moist; the bowels are readily acted upon by medi- cine, and the discharges are feculent, and, though somewhat clayey, contain a proportion of bile; but the urinary secretion is sometimes either not restored, or is considerably deficient for a day or two after the establishment of fever. In the progress of the fever, the tongue becomes black, and sordes accumulate about the teeth; the eyes become more and more injected; the intellect more and more torpid, though still the patient can be roused to answer questions, and make a sensible remark on his condition; but the instant the conversation ceases, the eyes are turned up in the orbit, exposing through their half-closed lids the red sclerotica, and the patient is in a state of profound stupor; urinary secretions are now esta- blished, and the urine, which at first was dark colored and cloudy, is now limpid and pale; the alvine discharges are darker colored than at first; and throughout the disease there is a deficiency of vascular action and of temperature, which we have not observed to the same extent in typhus, or any other fever. However flushed the countenance may appear— and it is often very considerably so—the temperature of the surface is below the healthy standard; and we have not often found the pulse above ninety. Typhoid is not an inappro- priate designation of the condition we have endeavored to describe; but we think that an individual who has once watched the progress of such a case, would run no risk of confounding it, on a future occasion, with typhus;—the defi- ciency of vascular and calorific power; the peculiar vascu- larity of the eye; the absence of subsultus and muttering delirium, (for though delirium occasionally occurs during night, the condition of the intellect throughout is much more one of torpor than of irregularity,) would be marked, by which he would discriminate the two affections. The dura- tion of such a febrile stage as we have described, is from a CHOLERA. 97 Week to ten days. Its termination has been, in a considerable majority of instances which have fallen under our observation, fatal. The brain appeared to us to be the organ mainly affected;.and by this view our treatment has been chiefly guided, though, at the same time, the condition of the intesti- nal canal has not been neglected. In another form, and one which supervenes on a minor degree of collapse than the preceding, the symptoms do not differ from those described above, excepting that there are indications of greater excite- ment—more warmth of surface or more force and frequency of pulse. Depletion could be more freely practiced, and it was altogether a more tractable form of disease. The mildest and most tractable type of the febrile stage is denoted by symptoms of general but moderate excitement, with epigas- tric pain or pressure, headache and giddiness; the tongue be- ing at the same time either clean, with a disposition to become dry and glazed, or slightly white and furred; the skin warm; the pulse free and forcible; the urine highly colored, and the thirst considerable. In such a case there is little or no con- fusion of thought or delirium, and the eyes are not injected. We need scarcely remark that examples of this mild and tract- able type of the febrile stage occurred after a choleric stage, in which the symptoms of collapse had been inconsiderable, in which the urinary secretion had not been suspended, or which had not always been attended with vomiting—a symp- tom occasionally wanting in slight cases. In the preceding sketch of the febrile stage, it will be understood that, as in the case of the choleric stage, we have not attempted to de- scribe all the various shades of intensity in which the disease manifests itself. The extremes only are given. To describe all the intermediate degrees would have swelled the article beyond reasonable limits, and would have proved a burden to the memory of the reader. 4th. Prognosis.—The danger of the disease is, in all cases, to be estimated from the degree of collapse attending the cold or choleric stage. In India, it was remarked that the cases in which spasms and vomiting were the most violent, were by 13 9S DISEASE AND ITS TREATMENT. no means fraught with the most peril; and what we have seen of the disease enables us to bear testimony to the accu- racy of the remark; for when we have heard the attendants exulting in the cessation of the spasms, and the facility with which the stomach retained medicine or food, and have felt, at the same time, the pulseless wrists, and the cold and clam- my hand, we have seen, in these apparently favorable omens, only the natural progress of the disease from a bad condition to one still worse. Whether we are to dread a fatal result in the cold stage, the intensity and duration of the collapse in the former of these stages are the measure of the danger; for if the patient die in this stage, he dies of collapse, and if he survive it, and pass into the state of fever, the character of this fever is malignant and dangerous, in proportion to the same collapse. 5th. Diagnosis.—From ordinary cholera the cold stage is to be distinguished, as it appears to us, by the peculiarity of the discharges, which has been sufficiently dwelt upon, and by the degree of collapse and its early occurrence. Cases have been adverted to, which, at least in the choleric stage, could not be discriminated from ordinary cholera, excepting perhaps, from their taking place at a season of the year when ordinary cholera is never observed; but it may be remarked, that no one would infer the existence of the epidemic from such cases, though he might be disposed to acknowledge that they belonged to it, if cases less equivocal were simultane- ously prevalent and especially if they originated under cir- cumstances mentioned in the preceding pages. We have been favored, by a gentleman of high character and attainments, with a report of two cases, regarded at the time they occurred, as aggravated cases of the ordinary dis- ease: both took place in the interior, under circumstances in which there was not the slightest ground to suspect contagion, and previously to there being any suspicion of the existence of the epidemic in this country. In one, the symptoms bore, unquestionably, a considerable resemblance to the choleric stage of the epidemic; but no fever supervened. The symp- CHOLERA. 99 toms of the other shall be given in the words of the writer: "The total, or nearly total suspension of the secretion by the kidneys; the watery vomiting and stools; the severity of the spasms; the shrunk and corrugated state of the skin on the hands and feet, and the blueness of his nails, persuaded me that his disease was of the spasmodic type. In him, moreo- ver, a slow fever succeeded the original symptoms, and long retarded his recovery." This case occurred in the beginning of July, 1831. There is a certain form of the febrile stage— that which supervenes on a choleric stage, attended with ex- treme collapse—which _ the deficiency of the teirperature and the circulation, the congested state of the conjunctiva from the very commencement of the fever, and the peculiar torpor of the intellect, would, as it appears to us, enable the observer to discriminate from any fever which we are in the habit of witnessing in this country, provided he saw the pa- tient early and watched him throughout; but in the majority of instances, the diagnosis can only be corr:ctly drawn by coupling the preceding history of the case with the existence of fever and with its character. 6th. Appearances presented on Dissection.—The exter- nal appearance of the body closely resembles that which has been noticed during life. The solids are shrunk, the surface is livid, the skin of the hands and feet is corrugated, the nails are blue, and the fingers are often rigidly contracted. There is no putrefaction, nor any characteristic fetor from the abdominal cavity. In the head are found marks of congestion, and occasionally even of extravasation. These occurrences were found very common by Doctor Davy, in dissections in Cey- lon; and Doctor Keir, of Moscow, discovered in the Russian form of the disease, the blood vessels of the brain and its membranes more or less turgid with blood, particularly to- wards the base, with a fluid effused into its convolutions, and more or less of serum in the lateral ventricles. In the thorax, the pleura and pericardium are found, as the serous mem- branes generally are in this disease, perfectly healthy, with the exception, occasionally, of an unusual dryness. The 100 DISEASE AND ITS TREATMENT. lungs are sometimes in a natural state, but more frequently gorged with dark colored blood, so as to resemble liver or spleen; or they have been found collapsed on each side of the spine, leaving the thorax nearly empty. This latter appear- ance Doctor Pollock explained by supposing gas to be extri- cated within the cavitv of the pleura; but the thorax having been opened in such cases under water, and no air having been found, Mr. Scott is disposed to ascribe it to a contractile power exerted by the viscus, sufficient to overcome the at- mospheric pressure. Both sides of the heart are in general distended with dark blood, and the bronchia are frequently filled with mucus. In the abdomen, the vessels of the liver are much congested, and pour forth blood copiously when incisions are made into that organ. But this congestion is not uniformly found; the gall bladder is turgid with black bile, and its ducts are sometimes constricted and impermea- ble, though occasionally in an opposite state. The peritoneum is often quite healthy, but the portion investing the alimentary canal has frequently an inflamed appearance, from the exceed- ingly loaded state of its blood-vessels. This congestion is sometimes so great as to give the appearance of gangrene; hut by drawing the finger over the surface, innumerable small veins may be found running in every direction, as in a pre- paration nicely injected, and the texture is found to be resist- ing and firm. This portion of the peritoneum, however, occasionally bears marks of actual inflammation, especially if the patient has lingered long before death. It then presents a thickened appearance externally, and its color varies from a pale vermilion, through all the deeper shades, to a dark pur- ple hue; the former being chiefly remarkable on the surface of the duodenum and jejunum, the latter on the ileum, where it terminates in the ccecum. At other times, the whole ali- mentary tube, instead of this congested state, presents a blanched appearance, both internally and externally. The omentum is sometimes healthy; at others, it presents the same appearance of extreme vascularity as the peritoneal sur- face of the alimentary canal. The following appearances are TIIOLERA. 101 discovered on laying open the stomach and intestinal tube: A white, opaque, and viscid substance is found adhering to the surface of some portions of the mucous membrane; and in many cases, it is so abundant in the intestines as completely to fill parts of them, of a greater or less extent. The stomach, and portions of the intestines, are filled with a transparent or turbid serous fluid, and frequently the viscid matter mentioned above is found intimately mixed with the serous fluid, or floating in it in the form of flakes. The mucus membrane, except when inflamed, which it not unfrcquently is, has an unnatural whiteness, is often soft and pulpy, and in general— especially in the stomach and small intestines—can be easily detached by scraping, in the form of thick pulp, from the subjacent coat. These appearances are sometimes more or less partial; but some of them are generally found throughout the whole extent of the tube. They extend, in some cases, to the mucous membrane of the bladder and ureters, and have been found, in some instances, in that lining the bronchia. The dissections in Sunderland have generally furnished results corresponding with those obtained elsewhere. In concluding this rather unsatisfactory portion of our subject, we cannot refrain from expressing a conviction, that the symptoms during life throw much more light on the nature of the disease, and its appropriate treatment, than appearances after death. 7th. Nature of the Disease.—Many writers have displayed much ingenuity in attempting to trace all the phenomena of the choleric stage, the stage which has been the principal sub- ject of investigation. But there has been but little accord- ance among medical reasoners, as to the part of the body in which the phenomena of the disease are presumed to origi- nate; for the nervous system generally, the ganglionic exclu- sively, the blood itself, and the lining of the digestive canal, have each been equally unable to sustain their cause. The diver- sity of these views, is a proof of the intricacy of the subject; and probably, also, since they have all proceeded from ob- serving and ingenious men, are evidence of the variable nature of the disease; each reasoner being, perhaps, influenced by that 102 DISEASE AND ITS TREATMENT. portion of the general phenomena of the epidemic, which pre- dominated in the cases it was his lot most frequently to witness. The partial nature, too, may be in a considerable degree as- cribed to the unfortunate influence on medical reasoners of the expression, proximate cause, as a substitute for the more comprehensive term, essence, or nattire of the disease. Even those who affect to use it as an equivalent term for na- ture of the disease, are yet insensibly influenced by the words they employ. Amidst the crowd of phenomena pre- sented to their notice in certain maladies, they often assume, on very insufficient grounds, that some one fact is the original of all others; and this they invest with the title of proximate cause. If the facts related respecting epidemic cholera are compared with the explanations offered of them, it will be found that each medical reasoner has attributed the com- mencement of the phenomena of the disease to an affection of some part of the frame; which affection unquestionably exists, in a very great number of instances, but neither with that uniformity, nor with that priority of time, which will war- rant us in concluding that it was the cause of all other symp- toms. It seems a rational supposition, that the remote cause of a disease may act, in some instances, first on one, in others on another part of the system, from some local weakness, or peculiarity of individual constitution, or from some specialty in the mode of application of the cause; and yet that the dis- ease shall retain, in each case, such a resemblance to a com- mon type, as shall prove its identity. It is likewise supposa- ble, that the remote cause may make a simultaneous attack on more than one organ, or part of the system. No one writer has been able to ascertain the proximate cause of cholera, either by inferences drawn from the symp- toms, or from appearances after death. It is gratifying to know that some light has been thrown on the subject, by which favorable practical results are obtained. That the ner- vous system generally, and the ganglionic and spinal nerves, and the spinal medula itself, are affected, is manifest from many symptoms; but whether this affection arises from a CHOLERA. 103 direct impression of the remote cause of the disease on these organs, or from irritation propagated from the alimentary canal, along the ganglionic nerves to the spine, we are igno- rant. Is the dark appearance of the blood to be explained by the feebleness of the action of the right ventricle, as a con- sequence of which little blood is transmitted through the lungs, and exposed to the influence of the air? According to this view, which is suggested with diffidence, the imperfec- tion of the respiratory process, will arise from the same cause as in congenital malformation of the heart, such as the per- sistence after birth, of the foramen ovale, or the aorta arising from both ventricles, in which a very small proportion of the whole mass of blood is oxidized. This hypothesis explains readily the dark appearance of the blood, its accumulation in the great veins of the viscera, the coldness and lividity of the skin, and the imperfection of the respiratory process, which has been so ably illustrated by Doctor Davy. This gentleman was the first to show that the air expired by pa- tients in the choleric stage, is colder, and contains less than the usual portion of the carbonic acid; and that this is the case, when the breathing is full, free, and rapid. The thick- ened consistence of the blood receives a ready explanation, from the loss of its serous part, by the abundant discharge from the inner intestinal surface. There are two morbid con- ditions of the lining of the digestive canal. In one it is in a manifest state of inflammation; in the other it is white and pulpy, and easily detached from the subjacent coat. The affection of the alimentary canal is essential and primary, if any part of the disease is so; and it were vain to attempt to trace it to a morbid condition of any other organ or sys- tem of organs. The general suspension of secretion, which is complete only when the collapse is extreme, appears to re- sult from the disorder of those systems, the nervous and vas- cular, on which this important function depends. That the whole series of the phenomena results from the action of a morbific poison on the body, there can be no doubt; but, as in the case of fever, we are yet ignorant of the precise nature 104 DISEASE AND ITS TREATMENT. of the primary change effected by it in various organs or sys- tems; and it is to be feared that, till more accurate ideas are attained, respecting the pathology of fever in general, this ignorance will remain. In the febrile stages, there are by no means, equivocal indications of inflammation of the brain, and occasionally of other organs, the analogy to fevers in general, being in this respect preserved. Many cases report- ed from abroad, lead to the opinion that the nervous system is primarily affected. Sth. Proportionate Mortality.—The mortality during the early prevalence of the epidemic in India, in IS 17 and 1818, was very great; but, either from the abatement of the inten- sity of the disease, or from the improvement of the treat- ment by our medical men, or, as is most probable, from the co-operation of both these circumstances, it was subsequently very much reduced. There is no disease in which unassisted nature seems more powerless than in this. WTe learn from the medical report at Bombay, that there is reason to believe that, of 1294 cases which received no medical assistance, every individual perished. From this appalling statement, it is gra- tifying to humanity to turn to the following records. Ac- cording to the documents collected by the medical board at Madras, the nubemr of deaths caused by it in the army of that presidency, during 1S18, was 4430, of which 695 oc- curred among the European troops, and 3735 among the Sepoys. The number attacked was 19,494—namely, 3664 Europeans, and 15,830 natives. The average strength of the army, during the period included in the report, being 10,112 Europeans, and 73,254 natives, it follows that, in five years, twenty-three and a third per cent, of the troops were attack- ed, and that of these twenty-two and three-fourths per cent. were carried off, or five and one-third per cent of the whole force of the army. We hear, in different situations, of rates of mortality infinitely lower than this. In some stations, not more than one in a hundred proved mortal, of those who were early succored. CHOLERA. 105 In our observations on the treatment, we shall follow the natural subdivisions adopted in describing the disease. I. TREATMENT OF THE INCIPIENT STAGES. We have adverted to two forms which this stage assumes. In the one there is some general uneasiness, nausea, and ver- tigo; in the other these affections may exist, with diarrhea, but the latter is frequently present, without the former being dis- cernable. The first of these forms—in which it may be re- marked, that medical aid is rarely applied to—requires that the stomach should be unloaded by an emetic, and a table-spoonful of mustard constitutes a very efficient one. A few ounces of blood should be drawn from a vein; a laxative of calomel and rhubard administered; and the patient restricted to a diluent diet, and kept within doors and warm. The treatment of the diarrheal form, to which, circumstances witnessed by us lead us to attach considerable importance, must be noticed more at length. It was mentioned that, in this diarrheal form of the incipient stage, the evacuations are at first found to be fcecal and bilious; but, at the time medical aid is summoned, they have generally assumed the serous character which they have in the choleric stage. A state of the system resembling, in some degree, collapse, it was observed, coincided with this condition of the alvine discharges. In this state,it was found very advantageous to give a dose of calomel, combined with a proportion of opium and some aromatic, and in twelve or fourteen hours afterwards, a dose of castor oil. On first visit- ing such a patient, a large blister was generally applied to the abdomen, in the cases under our care; warmth was enjoined —indeed, when compliance with our wishes could be en- forced, the patient was confined to bed—and it was directed that the diet should be diluent. The subsequent treatment consists in the employment of smaller doses of calomel and opium, for one or two successive nights, and a second dose of oleum vicini was sometimes administered. In certain local- ities, the writer has found the constitutional state accompany- ing this stage of the disease, to be one of marked excitement, 11 106 DISEASE AND ITS TREATMENT. rather than of feebleness and collapse; and some points of fhe abdomen have been painful on pressure. In such cases, one general bleeding, or the very liberal application of leeches to the abdomen, has preceded the employment of other reme- dies. It should be remarked, however, that the choleric stage has supervened, as we have been informed, on diarrhea, which had been skillfully treated; but our inquiries have uni- formly convinced us that, in such cases, medical aid had not been summoned till the diarrhea had existed sometime, and the subsequent stage was closely impending. II. TREATMENT OF THE COLD OR CHOLERIC STAGE. In order that we may be distinctly understood in our obser- vations on the mode of conducting this very important stage, We must adhere to its subdivisions into two periods. The first period is certainly that in which alone our most power- ful means of arresting morbid action, can be employed with a considerable prospect of success. It may be considered an axiom in medicine, that fevers, to be successfully must be early treated; and the rule has a powerful application to a disease so rapid in its course as that under consideration. But there are many obstacles to its being generally acted upon in a populous town; and one considerable obstacle, we appre- hend, will every where be found in the self deception which seems to be inspired by the disease. We have met with per- sons to whom, from their peculiar situation, all the symptoms of this disease were as familiarly known as to medical men; yet, when they were attacked with it, they did not or would not recognize it; and one such individual actually walked out with the disease upon him, and failed to send for assistance till eight hours after its invasion, though it was so severe as to destroy him in twelve. So strong is this tendency to self- deception, regarding the nature of the disease, when the chol- eric stage actually occurs, that, wherever cholera prevails, strong appeals to the public should be made on the necessity of early treatment of this stage, as well as due care of that which generally precedes it. CHOLERA. 107 The first remedy to be considered is blood-letting; and we shall endeavor to point out the circumstances, which, so far as our observation extends, indicate, and those which forbid its employment. Its safe employment should be early, not ac- cording to mere time only, but with respect to the rapidity of the disease; for one case may have made as considerable a ' progress towards actual collapse in two hours as another in ten; and we should regard a considerable degree of collapse indicated by feebleness or arrest of circulation, and percepti- ble in the intervals of pain and spasms, (for when these occur, the pulse often sinks instantly, though only a second before, it had been beating with consider ible vigor,) as an imperative reason for abstaining from drawing blood. But if we find the temperature not below, or but a little below, the healthy standard, a pulse of tolerable force, and strong spasms at short intervals, provided collapse have not preceded this favorable condition, we should at once open a vein, and not lose an op- portunity, which will never be restored, of probably prevent- ing extreme collapse, and either its immediate fatality, or its more remote, but scarcely less fearful evils. But should this condition, with respect to circulation and temperature, have succeeded to collapse, either spontaneously or by the adminis- tration of remedies, our experience would dictate that blood- letting should be carefully abstained from, as we have seen great injury produced, under such circumstances, by its em- ployment; cases having fallen under our notice in which the loss of three or four ounces of blood has destroyed the fruits of two or three hours assiduous labor. The difference in the effect of blood-letting on conditions apparently very analo- gous, but differing in the period, from the commencement of the attack at which they manifest themselves, cannot be too strongly impressed on the reader's attention. Perhaps the only difference in external character which can be discovered between the two states, will be the existence of spasms of considerable strength in the early period, whilst, in the more advanced, they have nearly, if not altogether, ceased; but in one case blood-letting breaks the morbid catenations, and pre- 108 DISEASE AND ITS TREATMENT. vents collapse and congestion; in the other it lowers the vital energies which are freeing themselves from a state of op- pression. But, again, in a more advanced stage, when the constitution is no longer balancing between collapse and fever, and the latter may be considered as established, bleeding is a suitable remedy, if the state of the circulation and the general condition of the patient render it admissible. Thus, then, there are three periods of the disease, at which according to our experience, blood-letting may be employed: occasionally in the incipient stage, as has already been stated, in the early part of the first period of the cold stage; and at the com- mencment of the feverish stage, under circumstances to be subsequently mentioned. We have been particular on this head, perhaps to prolixity, because we found great discrepancy in the testimony of various East Indian and continental au- thorities regarding it; and in the early part of our experience of the disease, the selection of the appropriate time for bleed- ing, and the circumstances which indicated or forbade it, con-= stituted the great difficulty we had to encounter. The meas- ure to be adopted next in succession to blood-letting, will depend on the condition of the patient. If, in a short time after bleeding, we find a circulation of tolerable force, without much tendency to general or partial deficiency of heat, and if, at the same time, there be a pain in the epigastrium increased on pressure, (a very common accompaniment of cases in which the tendency to collapse is least conspicuous,) a large blister or sinapism to the abdomen will be suitable remedies. Should the circulation, on the other hand, be feeble, with general or partial deficiency of warmth, we should endeavor to rouse the system by full vomiting; and powdered mustard is a very proper means for accomplishing this object. Half an ounce of this substance, suspended in half an ordinary tumbler of warm water, may be considered a medium dose, and one which, in a great majority of instances, will act promptly and powerfully; but, in a more advanced stage of the disease, when collapse has been extreme, a whole ounce has been required to produce the full effect. After full vom- CHOLERA. 109 king, sinapisms may be applied to the abdomen and along the spine; whilst the warmth of the patient is supported by bot- tles of hot water wrapped in flannel bags of hot oats, and other familiar methods of applying dry heat, directed to the extremities, or other points in which the temperature seems deficient. Friction of the parts affected with spasms will probably be required, and should be performed under the bed- clothes. The quantity of the liquid given at this period ought to depend on the condition of the patient; if, for in- stance, the tendency to collapse be considerable, a little weak brandy and water should be given at short intervals; but should the circulation be tolerably vigorous, and the tempera- ture good, simple diluents, such as toast and water, constitute the most suitable beverage. Should the patient be in a state of considerable collapse, whether in consequence of neglect of the earlier stage, or occurring, (which will occasionally prove to be the case,) in spite of the most diligent attention to it, blood-letting should not form part of the remedial agents selected. In the sinking stage of the disease, various stimu- lating remedies have been recommended. Whatever stimu- lant medicine be employed, we would advise that calomel in doses of five or six grains, repeated at intervals of three or four hours, be given at the same time, with the view of aiding the restoration of secretions; and with the intention of at once rousing the system, and lessening the irritability of the stomach; and also that a large sinapism should be applied to the abdomen, and another along the course of the spine. The tobacco enema has been suggested by Mr. Baird of New- castle, and, as he assures us, employed with considerable suc- cess. Weak brandy and water may be given occasionally during the collapse; and we have observed no injurious effect, in this or any stage of the disease, from the ordinary diluent taken in moderate doses. III. TREATMENT OF THE EXCITED, OR FEBRILE STAGE. This division of the subject will not require so lengthened a discussion as the preceding, which may be considered as 110 DISEASE AND ITS TREATMENT. more exclusively belonging to this disease; for recognized principles, applicable to the treatment of pyrexia in general, must be our guides in treating this fever. The fever consti- tuting this stage, be it in essence what it may, has inflamma- tion accompanying it, of which the principal locations are the brain and lining of the digestive canal; and to the subduing of these, by such measures as the state of the system admits, our attention should be carefully directed. A form of fe- ver has been described as supervening on an extreme and long-continued collapse in the cold stage, and in which it was mentioned that the vascular action was low and feeble, the temperature of the surface under the healthy standard, and the description of warmth very partial. A degree of irritability of the stomach, with occasional vomiting, is a very frequent accompaniment of such a case, for two or three days; and, under such circumstances, leeches, and subsequently a blister to the epigastrium, have been resorted to. Of internal remedies, calomel is the most to be relied on, from its effects on the secretions, particularly of the intestinal canal, and from its facilitating the laxatives which the state of the brain ren- ders advisable to administer. Simultaneously with this, atten- tion should be paid to keeping up the heat of the cold parts of the body, by bottles of hot water wrapped in flannel. Even when relieving the system by bleeding, stimulants may be required, to keep up the action. The more excited form admits of one general bleeding with advantage, the amount of blood to be drawn being regulated by the various circum- stances which would govern in ordinary fever. Should the head, as it generally does, continue to be affected after blood- letting, leeches and cold applications should be resorted to, the former being repeated, if necessary, to such extent, and at such intervals, as the degree of headache, intellectual torpor, and vascular excitement, may seem to require. Laxative medicine should be administered; calomel at night, and castor oil in the morning. That kind of permanent fomentation, which is afforded by hot poultices on the abdomen, has been found beneficial. In most cases of high excitement, as well CHOLERA. Ill as the lowest form of the disease, in which the collapse of the cold, seems prolonged through the febrile stage, it is advisable to counteract, by warmth, applied to the extremities and other points, that tendency to irregular distribution of blood, which forms so striking a feature of the disease. As to the Proximate Cause, or Pathological Inception of Cholera.—On this subject, similar diversities of opinion prevail, among the physicians of this country, to those we have already noticed among the profession in other parts of the world. Some suppose the unknown poisonous influence to make its first morbid impression on the mucus membrane of the stomach and bowels; others, that the nervous texture, in general, or the ganglionic system, specially, is the first to feel its baleful operation; others, that a failure of the active powers of the heart and blood-vessels take the lead in this unmanageable train of marked actions; others, that the fluid they contain, becoming decomposed or deteriorated, occasions all the formidable symptoms of the disease; and lastly, there are those who believe that the proximate cause of cholera as- phyxia consists in a simultaneous modification of all the or- ganic powers and functions, the poison acting either directly on the properties of the several textures, or indirectly through the nervous system. Which of these speculations has the advantage, either in the number or respectability of those who entertain it, we are unable to determine. Many of the agents adopted, as laid down in the foregoing article, for the treatment of cholera, are such as we would recommend, as accordant with our mode of treating this dis- ease. But so far as depletions, leeches, epispastics, and calo- mel, are concerned, we are enabled, by the application of our remedies, to dispense with them. By giving action to the blood, we avoid the danger (a danger which is admitted) that sometimes attends blood-letting, and also the prostration of the patient, which is the necessary result of that practice. Our agents, which are intended to give action to the system generally, are more ready and certain in their operation, than calomel, and dispatch and certainty are objects of vital im- 112 DISEASE AND ITS TREATMENT. portance in contending with a disease so swift as this. The fact that all our external remedies determine the disease to the surface of the body, more readily and more successfully than blistering, will recommend them in preference thereto. The powerful effects of a combination of concentrated stimu- lants, tonics, diaphoretics, and anti-spasmodics, of which our remedies are composed, and which enter every part of the body at the same time, in cases of cholera, need no argument to induce every reflecting man of science to give them a can- did consideration, and we feel justified by experience, in say- ing, that we doubt not that, with as many as shall make a thorough, persevering trial of them, the continuance of their application in all cases of cholera, will be the certain conse- quence. Though the disease is of a character which is more terrific than any which has ever afflicted our race; has spread abroad desolation and alarm in their most direful forms; has frightened husbands from the bed of their dying companions, and from the terror created, has been a fruitful cause of pro- ducing attacks on the subjects of its alarm; though all such have been its sad consequences, and will so continue to be until it shall be known and believed that an antidote is dis- covered, which wrill arrest its march of death; it is our plea- sure to state, with the fullest confidence, established from actual experience, that our remedies are abundantly com- petent to arrest the disease, in all its forms. In many respects, we treat the cholera as we do congestive fever, though not entirely so. Let the patient be rubbed over the whole body (with the least possible delay) with our Fe- ver Liniment; prepare plasters of the same, and bind them on the bowels, breast, wrists, and ankles, repeating the rubbing of the other portions of the body with the Liniment, and prepare hot bricks to lay at the feet and sides, to promote perspiration; administer an injection of our Pectoral Tinc- ture, at the same time give an emetic of the same, in tea- spoonful doses every five minutes, and if vomiting does not take place in fifteen minutes, double the dose; still continue the rubbing on of the Liniment: while this is going on, let PLAGUE. 113 some one prepare a mustard poultice, to be placed over the plasters on the breast and bowels, which will accelerate the absorption of the Liniment: after vomiting, give tea-spoonful doses of the Diaphoretic Drops, and (apply the Liniment freely on the whole length of the spine, with much friction,) then the tincture of gum myrrh. If the stomach remain sick after vomiting freely, drink liberally of strong pepper- mint or spearmint tea, These measures, persevered in, will soon cause a reaction in the system; the spasms will subside, all the symptoms will be removed, and the patient's recovery will generally be as sudden as was his prostration. We have the evidence of a number of desperate cases having been sud- denly overcome by some of these means, and not a single failure has come to our knowledge. PLAGUE. This is a disease characterized by a contagious typhus, en- tire prostration of strength, and by certain local symptoms, as buboes, carbuncles, livid spots, (petechias.) The latter are, in this connection, the peculiar characteristics of the plague, since the former also appear in other malignant diseases. In the beginning, the patient generally experiences great mental dejection,and corporal debility; slight chills, alternating with heats, which are afterwards succeeded by a burning heat with- in, and a heaviness about the head; then follows stupor; the eyes are glaring, glazed, or wild and sparkling; the face ap- pears whitish and livid; and the patient is melancholy, morose and anxious, faint and delirious. In many cases nausea and vomiting occur. The thirst is unquenchable, the tongue is reddish or yellowish, the speech indistinct. In the progress of the disease, the face often becomes red, the perspiration quick and uneasy, and bilious, green, or bloody and black matter is vomited. The delirium often becomes mild; the urine is sometimes turbid, black, whitish, or bloody; and hemorrhages take place, when death does not immediately ensue. Buboes appear in the groins, the arm pits, the paro- 15 114 DISEASE AND ITS TREATMENT. tids, and other places, with carbuncles, or small, yellowish black spots, over the whole body. The fear, anxiety, and despair, which seize the patient on the first appearance of the plague, increase the danger of the disease. Death, in many cases, takes place on the first day, and frequently in a few hours after the attack, but sometimes not till the second or third day. It is considered favorable if the buboes and carbuncles appear at the same time, are very numerous, and terminate in suppuration. They either terminate in suppura- tion, or become indurated, are healed or cut out. In regard to the origin of the plague, and the manner in which it is communicated, very different opinions have been entertained, according to the state of medical science. In early times, when calamitous events, the causes of which were not understood, were attributed to spirits and demons, the plague was ascribed to their influence. At a later period, it was accounted for by changes in the air, poisonous vapors which descended from the atmosphere, or to clouds of insects which were received into the body, by inspiration, or in the food, or by absorption through the skin, and thus corrupted the blood. Physicians, according to the tendency of their theories, found the cause in the excess of sulphureous matter in the blood, or in its coagulation, or resolution, etc. Many have considered it as not contagious, but at present there is a very general conviction of its contagious character. The plague is a specific disease, and can originate of itself only in certain countries. Hot weather, bad air and food, and filthiness, favor its production and propagation. The nature of the disease seems to exist in a diminution of vital energy, which may be so rapid and universal, that the com- ponent parts of the system, particularly the blood, lose their natural properties, and become corrupted, and life is destroyed before the nervous system is able to counteract the effects. When the progress of the disease is not so rapid, the vital energy which remains, is exhausted by febrile excitements, and local inflammation. Dissections have shown collections of coagulated or decomposed fluid, black blood, inflammations PLAGUE. 115 of large portions of the skin, and carbuncles in great num- bers. The buboes discharge an offensive matter, and extend far inward. The carbuncles, which precede the approach of death, and which contain mortified parts, also generally reach deeply inwards. When nature possesses sufficient vigor, the inflammations are on the skin, rather than in the interior. The buboes soon terminate in suppuration, and the carbuncles, when cut, discharge a less corrupt matter, and fall off. The fever is carried off by a violent sweat, the recoveryT is slow. When the disease is completely developed, it is contagious; to this is owing the terrible devastations which it causes. There is but little doubt the plague appeared in the most ancient times, particularly where a numerous population was collected together in warm climates; but we must not consider every disease a plague, which has been called so by historians, as they often mean by the term nothing more than a malig- nant disorder, prevailing over a considerable extent of coun- try. Among the most famous instances, is the plague descri- bed, in so masterly a manner, by Thucydides, which, in the third year of the Peloponnesian war, (430 B. C.) ravaged Athens, then besieged by the Spartans. A large number of the inhabitants of Attica had fled into the city; fear, anxiety, want or badness of provisions, and the corruption of the air, caused by the crowded state of the population, produced and propagated the plague in the city. Death generally ensued after the seventh or ninth day. The plague in Jerusalem (A. D. 72,) when it was besieged by the Romans, is described by Josephus. In Rome, the plague prevailed (A. D. 77) in the reign of Vespasian; of Marcus Aurelius (170,) when it raged over almost all Europe and Asia; of Commodus (189,) and particularly of Gallienus, (in 262,) when five thousand per- sons are said to have died daily in Rome. From that time, it continued occasionally to prevail in Italy, Greece, Asia, and Africa, and raged particularly in the populous cities, for instance in Constantinople, in the reign of Justinian, (in 544,) when one thousand grave diggers were said to have been in- sufficient for the interment of the dead. This plague con- 116 DISEASE AND ITS TREATMENT. tinued its ravages for fifty years, with but short intervals. In 565, it appeared under the name of pcstis inginnana in Treves, and in 588 at Marseilles. In the seventh century it appeared in Saxony. In 823 it prevailed all over Germany; and from 875 to 877, was particularly malignant in Saxony and Misnia, as was also the case in 964. In the eleventh century it broke out in Germany at least six times, mostly after or during the famine, and raged with so much violence it was believed that all mankind was doomed to be swept away by it. This unfortunate belief prevented the taking of effec- tual means to check it; and apathy in suffering was consider- ed an act of piety. In some cases, however, the Jews were suspected of having poisoned the wells, as in our own time, the Hungarian peasantry suspected the nobility, when the cholera morbus swept away so many of the poorer clases. In fact, the ignorant of all ages have been inclined to ascribe general and far spreading diseases, whose causes are unknown or disbelieved in by them, to poisoned wells. Thus, the writer recollects, that when the ophthalmia broke out in the Prussian army in 1813, many believed that the French had poisoned the wells. Similar notions were entertained by many French soldiers, during the plague which swept them off in Egypt. In the twelfth century, the plague prevailed in Germany about twenty-five years. In the thirteenth century it was brought into Europe by the Crusaders. From 1347 to 1350, it traversed all Europe, and was then called the black death. Since that time it has never ravaged with so much violence. Boccaccio, in the introduction of his Decameron, has given a lively description of its physical and moral effects in Florence, in 1348. In the latter half of the fifteenth cen- tury, it raged in all Europe, and was accompanied by the most terrible sufferings. The historians of that time give the most horrible picture of distress. In the sixteenth century the plague again raged, and in 1563 was again introduced into England, by the return of an English army from the conti- nent. At the same time the sweating sickness prevailed on the continent, which had been imported from England, to- PLAGUE. 117 wards the close of the fifteenth century. It was called in Germany, the English sweat, and spread from the seaports, over Germany, France, the Netherlands, and Italy. Though some means were already taken against the plague, for in- stance, the establishment of lazarettos, yet it raged in Europe during the seventeenth century. In 1603, 1625, 1636, and 1665, it made great ravages in England. As the plague never ceases in the East, in Greece, and in European and Asiatic Turkey, it has continually been introduced by vessels, into the ports of Italy and France; and has also been propa- gated in Western Europe, through Hungary, Poland, and Transylvania. The quarantine rules have not, in general, been stictly observed, and as late as 1720, a Levantine vessel imported the plague into Marseilles, which soon spread all over Provence. In 1795 and 1796, it extended over the countries into the Turkish frontiers, but was checked by the skill of the physicians. It broke out in 1816, at Noia, a town in the Neapolitan territories. The ancients endeavored to avert the plague by sacrifices, the christians by processions and prayers. The ancient phy- sicians tried several modes of treatment; among them, sweat- ing. The researches of modern physicians have given us a greater insight into the nature of disease, and of its remedies, than were possessed formerly, when want of courage was quite as fatal as want of knowledge. Precautions against contagion, and when that has once occurred, the speedy ex- pulsion of the poison from the system, the diminution of the internal inflammation, the preservation of the vigor of the arterial blood, the strengthening of the nerves, the promotion of suppuration, the seasonable resolution of the carbuncles, are the main points of the treatment. Baldwin, English Consul Gen- eral at Alexandria, recommended (1795) oil friction, which has been tried with success. Having observed that oil-porters were never attacked, he concluded that olive oil was a preservative against the plague, and his expectations were surpassed by the favorable results of his process. As soon as any symptom of the plague is discovered, the body of the patient is quickly 118 DISEASE AND ITS TREATMENT. and vigorously rubbed with warm oil, and he is put to bed. This application is followed by a profuse sweat, which is pro- moted by alder tea. The friction is repeated, once or twice a day, until a violent sweat is produced. If there are buboes, they must be frequently rubbed with oil, until suppuration follows. Doctor Madden, in the work already quoted, gives the following as the results of his experience, both in regard to the nature of the disease, and the treatment of it: " I have given plague the name of typhus gravissimus. The symp- toms, from the first, are, general debility, congestion about the heart, not depending upon inflammation, but upon the putrescent state of the circulation. It differs little from pu- trid typhus, except in its duration and eruptions. In every stage of plague, nature appears to be prostrate under the in- fluence of the poisonous miasma; and when the patient sinks at last, it is from the want of force in the constitution to drive out the eruptions on the surface. The bubo recedes, or the carbuncle diminishes, or neither appear at all externall}T; but they have seized on the internal vital organs, and the imme- diate cause of death has been shown by dissection to have been carbuncles on the liver, lungs, spleen, or mesenteric glands: in short, it appears that the whole glandular system is the seat of the disease. I have seen all the different spe- cies of plague enumerated by Russel and the French authors, and I have no hesitation in pronouncing all these different species of plague to be the symptoms of one class only: and I assert there is but one indication to fulfill; namely, to assist nature to expel the poison, by strengthening the exhausted powers of the constitution, and enabling it to throw out the morbific matter. By what means is this to be done?—whether by emetics, by purgatives, by bleeding, by calomel, by mer- curial unction, or by oil friction? There are none of these means I have not tried, and out of the first eleven patients I so treated, I lost nine. I had recourse to another mode of cure; strong stimulants, diffusible and permanent, I now tried. I commenced with wine and brandy, the first moment I saw the patient, whether the eye was suffused, the cheek flushed, PLAGUE. 119 and the skin arid, or the low delirium set in, or not. I ad- ministered it in the following; manner: The first dose was a tumbler of hot brandy and water, about one-third spirit. This sometimes was vomited, and again repeated; the second time it usually remained on the stomach, and in the course of two hours, it generally produced perspiration, even after James' powder had failed. Two or three hours after the first dose, another was administered, and the patient would feel less of the burning pain at the heart. If vomiting supervened, it was again repeated, and during the day it was now given every four or six hours, according to circumstances. The buboes commonly increased in size, and profuse sweating was often followed by petechias, or livid spots on the chest: when I saw this, I was always sure of my patient. The second day, I increased the strength of the dose; instead of one-third spirit, I gave one-half, every eight hours; no intoxication came on, but a lethargic drowsiness was common enough, continuing till the perspiration broke out, or carbuncles ap- peared externally. If on the third day the patient was de- cidedly better, I kept up the excitement by strong Cyprus wine, in frequent but small doses of two table-spoonsful every two hours; but if the bad symptoms were unabated, I con- tinued to give the hot brandy and water, in increased quanti- ties, till some decided change took place. This active treat- ment it was seldom necessary to pursue beyond the sixth day; indeed, in plague, if the patient live till the sixth day, he is likely to recover; but the third day is that which is most to be feared. The only other treatment, was once or twice opening the bowels with enemas, for purgatives by the mouth do no service, and sponging the body frequently with vine- gar and water; the head was constantly kept soaked with towels dipped in vinegar, and the buboes were poulticed with very hot cataplasms, sufficiently hot to give pain, and they were allowed to burst spontaneously. With this treatment, at the rate of seventy-five per cent, recovered. In Candia, of nine patients, five patients recovered, and some of these were almost hopeless cases when I began to treat them. 120 DISEASE AND ITS TREATMENT. Every thing in plague, of course, depends on early treatment; for, in a disease which commonly runs its course in three days, there is no time to be lost." Remark.—In tracing the history of the plague, it appears that for a long time physicians were unable to adopt a treat- ment which proved successful, or which in any manner ar- rested the disease; and not until 1795 was the external ap- plication of sweet oil discovered to be competent to accom- plish that object. After this discovery, it was found that stimulants and diaphoretics would cause a free perspiration, and throw off the morbific matter; and by a persevering course of this treatment, vast numbers of those who were attacked with the plague were saved. It was further ascertained, that the great variety which physicians had supposed to exist in this disorder, and which had caused so much indecision in the treatment of it, was nothing more than the various symp- toms of the same complaint. It is hardly possible to produce stronger evidence of the superiority of our system for the treatment of disease, than is here contained. AGUE. Ague is a disorder belonging to the class of intermittent fevers. It may be followed by serious consequences, but, generally, it is more troublesome than dangerous, and is some- times even considered salutary. According to the length of the apyrexia, or intermission between one febrile paroxysm and another, agues are denominated quotidians, tertians or quartans', which latter, are much the most obstinate, being generally attended with a greater degree of visceral obstruc- tion than those, the attacks of which return at shorter inter- vals. The quartan ague is apt to terminate in dropsy. An ague paroxysm has been divided into the cold, the hot, and the sweating stages. The feeling of extreme cold, in the first stage, cannot be prevented by fire, or the heat of summer. Generally, after the sweating stages, in which there is a pro- AGUE. 121 fuse exhalation from the pores of the skin with a flow of urine, depositing a copious sediment, of a lateritious or brick-dust appearance, the patient falls into a refreshing sleep, from which he awakes without any remains of indisposition, except a slight degree of languor and debility. Agues occur chiefly in situations where there are shallow, stagnant waters. Hence their frequency in Holland, in the East and West Indies, in the flat, marshy parts of England, and the thinly settled parts of the United States, where they diminish with the clearing; of the woods and the draining, of the lands. The neighborhood of rivers or marshes, therefore, is carefully to be avoided by persons afflicted with agues. They are cured by medicines, which, at the same time that they exert a tonic influence, produce and keep up an impres- sion upon the system greater than that communicated by the cause of the disease. Ague Cake is a hard tumor on the left side of the belly, lower than the false ribs, and said to be the effect of intermit- tent fever. TREATMENT. A partial description is given of the treatment of this com- plaint in another part of this work. We will here observe, that a knowledge of the time of a returning paroxysm being almost certain, the patient may uniformly avoid it by the fol- lowing treatment, viz: Some time previous to the return of the cold stage, let the patient take his bed; apply our Fever Liniment over the whole body, at the same time take a half tea-spoonful of Diaphoretic Drops, once in ten or twenty minutes; place warm bricks to the feet and sides, w7hen a per- spiration will break out: then keep up this perspiration by warm herb tea for two hours; afterwards wash off the body and then again apply the Liniment; put on clean dry under- clothes—and seldom if ever will it be necessary to have re- course to this treatment a second time. There is another advantage gained by this course: the disease is not so likely 16 122 DISEASE AND ITS TREATMENT. to supervene as it otherwise would be, or if the sweating pro- cess was to be dispensed with. An ague cake is uniformly removed by applying a plaster of the same Liniment on the side, and taking plentifully of the Diaphoretic Drops. CHAP. III. PHTHISIS, OR PULMONARY CONSUMPTION. This disease is more frequently found in cold climates than in warm. The causes which predispose to it, are very nu- merous. The following are, however the most general:— Hereditary disposition; peculiar formation of the body, obvi- ous by a long neck, prominent shoulders, and narrow chest; scrofulous diathesis, indicated by a fine clear skin, fair hair, delicate rosy complexion, large veins, thick upper lip, a weak voice, and great sensibility; certain diseases, such as syphilis, scrofula, small pox, and measles; particular employments, exposing artificers to dust, such as needle pointers, stone cut- ters, millers, etc., or to the fumes of metals or minerals under a confined or unwholesome air; violent passions; agitation of mental affections, as grief, disappointment, anxiety, or close application to study without proper exercise; frequent and excessive debaucheries; late watching; drinking of strong liquors; great evacuations, as diarrheas, diabetes, excessive venery, fluor albus, immoderate discharge of the menstrual flux; the continuing to suckle too long under the debilitating state; and, lastly, the application of cold, either by a too sud- den change of apparel, keeping on wet clothes, lying in damp beds, Or exposing the body too suddenly to cool air, when heated by exercise; in short, anything that gives considerable check to perspiration. The more immediate or occasional causes of phthisis, are hemoptysis; inflammation in the lungs, proceeding to inflammatory tumors; catarrh; asthma; and tu- bercles, or swelling knots; the last by far the most general. The incipient symptoms usually vary with the cause of the disease, but wdien it arises from tubercles, it is thus marked: It begins wTith a short, dry cough, that at length becomes ha- 124 DISEASE AND ITS TREATMENT. bitual, but from which nothing is spit up for some time, except a frothy mucus, that seems to proceed from the fauces. The breathing at the same time is somewhat impeded, and upon bodily exertion, is much hurried; a sense of straitness, with oppression at the chest, is experienced; the body gradually becomes leaner, and great, languor, with indolence, dejection of spirits, and loss of appetite, prevails. In this state, the patient frequently continues a considerable length of time, during which he is, howTever, more subject than usual, to slight colds, and upon one or other of these occasions, the cough becomes more troublesome and severe, particularly by night, and is at length attended with an expectoration which, towards morning, is more free and copious. By degrees, the matter which is expectorated becomes more viscid and opaque, and now assumes a greenish color and purulent appearance, being, on many occasions, streaked with blood. In some cases, a more severe degree of hemoptysis prevails, and the patient spits up a considerable quantity of florid, frothy blood. The breathing at length becomes more difficult, and the emaciation and weakness go on increasing. With these, the person be- gins to be sensible of pain in some part of the thorax or breast, which, however, is usually felt at first under the breast, palate or sternum, particularly on coughing. At a more advanced period of the disease, a pain is sometimes felt in one side, at times prevailing to so high a degree, as to prevent the person from lying on that side; but it more frequently happens that it is felt only on making a full inspiration, after coughing. Even where no pain is felt, it often happens that those who labor under consumption, cannot lie easily on one or the other of their sides, without a fit of coughing being excited, or the difficulty of breathing being much increased. At the first manifestation of the disease, the pulse is often natural, or per- haps is soft, small, and a little quicker than usual; but when the symptoms which have been enumerated, have subsisted for any length of time, it then becomes full, hard, and fre- quent. At the same time, the face flushes, particularly after eating; the palms of the hands, and the soles of the feet, are PULMONARY CONSUMPTION. 125 affected with burning heat: the respiration is difficult and la- borious. At evening the symptoms increase; and by degrees the fever assumes a hectic form. This species of fever is evidently of the remittent kind, and increases in symptoms twice every day. The first occurs usually about noon, and a slight remission ensues about five in the afternoon. This last, however, is soon succeeded by another symptom, which in- creases gradually until after midnight; but about two o'clock in the morning, a remission takes place, and becomes more apparent, as the morning advances. During the exacerba- tions, or increase of symptoms, the patient is very suscepti- ble to any coolness of the air, and often complains of a sense of cold, when the skin is, at the same time, preternaturally warm. In the evening, these exacerbations are by far the most considerable. From the first appearance of the hectic symptoms, the urine is highly colored, and deposits a copious, branny, red sediment. The appetite, however, is not greatly impaired; the tongue appears clesn; the mouth is usually moist; and the thirst is inconsiderable. As the disease ad- vances, the fauces put on rather an inflamed appearance, and are beset with aphtha, or sore mouth, and with small, white ulcers on the tongue, gums, and throat, resembling small par- ticles of curdled milk, and the red vessels of the tunica adnata, or white of the eye, become of a pearly white. During the exacerbations, a florid, circumscribed redness appears on each cheek; but at other times, the countenance is pale, and some- what dejected. At the commencement of hectic fever, the person affected is usually costive; but in a more advanced stage, a diarrhea often comes on, and this continues frequently to recur during the remainder of the disease. Colliquative, or severe sweats, likewise break out, and these alternate with each other, and induce exceedingly great debility. In the last stage of the disease, the emaciation is so great, that the patient has the appearance of a walking skeleton; his counte- nance is altered, and his cheeks are prominent, his eyes look hollow and languid, his hair falls off, his nails are of a livid color, and much incurvated, and his feet are swollen. To 126 DISEASE AND ITS TREATMENT. the end of the disease, the senses remain entire, and the mind is tranquil, and full of hope. It is, indeed, a happy circum- stance attendant on phthisis, or consumption, that those who labor under it, are seldom apprehensive or aware of danger; and it is no uncommon occurrence to meet with persons la- boring under its most advanced stage, flattering themselves with a speedy recovery, and forming distant projects under that vain hope. Some days before death, the extremes be- come cold. In some cases, a delirium precedes that event, and continues until life is extinguished. As an expectoration of mucus from the lungs may possibly be mistaken for purulent matter, and may thereby give us reason to suspect that the patient labors under phthisis, or consumption, it may not be amiss to point out a sure criterion by which we shall always be able to distinguish the one from the other. The medical world are indebted for the discovery to the late Mr. Charles Darwin, who has directed the experi- ment to be made in the following manner: Let the expecto- rated matter be dissolved in vitriolic acid, and in caustic lixi- vium, and add pure water to both solutions. If there is a fair precipitation in each, it is a certain sign of pus; but if there is not a precipitate in either, it is certainly mucus. Sir Everard Home, in his dissertation on the properties of pus, and the means of distinguishing accurately between pus and animal matter, asserts, that the property which characterizes pus, and distinguishes it from most other substances, is, its being composed of globules, or round particles, which are visible when viewed through a microscope; whereas animal mucus, and all chimical combinations of animal substances, appear in the microscope to be made up of flakes: this pro- perty was first noticed by the late Mr. John Hunter. Pul- monary consumption is, in every case, to be considered as attended with much danger; but it is more so when it proceeds from tubercles, or round, corrupted pimples, than when it arises in consequence either of hemoptysis, or pneumonic suppuration, (inflammation in the lungs, and inflamed mucus deposited in the lungs). In the last instance, the risk will be PULMONARY CONSUMPTION. 127 greater, where the abscess breaks inwardly, and gives rise to empyema, or pus in the thorax, than where its contents are discharged by the mouth. Even cases of this nature have, however, been known to terminate in immediate death. The impending danger is generally to be judged of, however, by the hectic symptoms; but more particularly by the fetor of the expectoration, the degree of emaciation and debility, the extreme sweats, and the diarrhea. The disease has, in many cases, been found to be considerably retarded in its progress by pregnancy; and in a few instances, it has been alleviated by an attack of mania, or madness. The morbid appearance most frequently to be met with, on the dissection of those who die of phthisis, or consumption, is that of tubercles in the cellular substance of the lungs. These are small tumors, which have the appearance of indurated glands. They are of different sizes, and are often found in clusters. Their firmness is in proportion to their size; and when laid open in this state, they are often of a white color, and of a consistence nearly approaching to cartilage. Although tranquil at first, they at length become inflamed, forming little abscesses, or vomicae, in the lungs, which, breaking and pouring their contents into the bronchia, or throat, give rise to purulent expectoration, and thus lay the foundation of phthisis, or consumption. Such tubercles, or matter, are most usually situated at the upper, and back part of the lungs; but in some instances, they occu- py the outer part, and then adhesions to the pleura are often formed. When the disease is partial, only about a fourth of the upper and posterior part of the lungs, is usually found diseased; but in some cases, life has been protracted till not one-twentieth part appeared, on dissection, fit for performing their functions. A singular observation, confirmed by the marked collections of anatomists, is, that the left lobe is much oftener affected than the right. The indications are, first, to moderate inflammatory action; second, to support the strength, and promote the healing of the lungs; third, to palliate' urgent symptoms. 128 DISEASE AND ITS TREATMENT. To effect the objects just mentioned, our system is alto- gether new; the principles upon which it is based having been adopted, heretofore, only in part. We reach the diseased or- gans through the medium of cutaneous absorption—depend- ing principally upon the sanative powers of our external agents; and from demonstration, we hazard nothing in saying, that we can prepare nearly all remedial agents, and introduce them into the system through this medium, so as to produce the desired effect, much more readily than by the common mode of exhibiting through the stomach. With this we also combine the desideratum of releasing the internal organs from the great action, necessary to be undergone, by medi- cines passing the digestive function, which all grant is most grateful to the enfeebled state of the patient. In all pectoral diseases, or complaints of the chest, we are opposed to the giving of strong medicines internally, at least in large doses, often repeated, for the reason already stated, that in a healthy state, all the energies of the stomach are called forth to per- form their office; hence their inability to perform digestion when enfeebled. In all its stages, we have been enabled to discover the most decided advantage by the use of our reme- dies. They excite the torpid organs to action, impart a most efficient tonic to the worn out and enfeebled patient, while they allay inflammation, and enable a free and gentle expec- toration; readily removing the obstructed matter, and leaving the patient in a state of tranquillity. From experience and observation for some time past, we are led to fix upon the fol- lowing mode of TREATMENT. In cases where the lungs are inflamed only, and the patient has not for a great length of time been subject to a cough, relief may be granted by applying our Cough Liniment to the side, and between the shoulders, two or three times a day; at the same time taking the Vegetable Syrup, or if that be not at hand, take from four to twelve drops of the Pecto- PULMONARY CONSUMPTION. 129 ral Tincture three times a day, and at night apply plasters spread with the Liniment, and a warm brick to the bottoms of the feet, and take some warm herb tea to cause free perspira- tion; at the same time, Tonic Bitters may be taken two or three times a day, to sustain the strength of the patient. In more advanced stages, where the patient shall have been af- flicted with a light cough a long time, pains in the breast, sides, and shoulder blades, hemiplegia, and emaciation, with evident symptoms of the lungs having become ulcerated, a more ela- borate course ought to be pursued—the Liniment should be worn on plasters, applied to the breast, back, and on the bot- toms of the feet, renewed twice a day. If the system has become very impure, this will cause small pustules to appear on the surface in two or three days, which will discharge virulent pus. The parts should be washed with warm Castile soap suds at each dressing, and once in two or three days the patient should be washed entire, in warm soap suds, then in salt and water, make free use of the flesh brush, and apply the Liniment again. The Liniment should also be rubbed over the whole body, particularly the throat and spine. If the pustules become too sore for the Liniment to be borne on them, the Vegetable Cerate may be applied for a few dress- ings, and then the Liniment resumed. The Cough Syrup should be taken three times a day, in tea or table-spoonful doses, as the tickling sensation attending the cough may de- mand. The Pectoral Tincture must also be administered, in doses of from three to twelve drops, as occasion may require* This article is one of the best expectorants known; and when taken in large doses, excites nausea and vomiting—but we seldom find it necessary to produce this effect. If the patient has chronic wandering pains, an under dress of white silk is valuable to be worn. The diet should be light, exercise moderate, night and damp air avoided, and the feet kept warm. In cases of ulceration, this course will generally cause a discharge of matter in two or three days, sometimes by vomiting, and at other times by the intestinal canal. If port wine is agreeable to the patient, it may be taken in small 17 130 DISEASE AND ITS TREATMENT. quantities. We have known some instances of sudden relief by the course here recommended. In such cases, it will be absolutely necessary for the patient to follow up the remedies, or at least to apply the Liniment for a considerable length of time, to confirm a cure. But if through the agency of exter- nal remedies, the morbific matter can be expelled from the system, the digestive organs restored to a healthy tone, and the whole functions of the body strengthened, there is much gained towards the restoration of health. These effects, it has appeared, we have been enabled to produce, principally, by our remedies externally applied; for by the use of the Lini- ment on the stomach and bowels, we have frequently known a healthy state of both to take place, though not always with- out the aid of some medicine taken into the stomach. To aid in the relief of the cough, we sometimes prepare a Syrup in the following manner: Take two pounds of turnips, and slice them one-third of an inch thick; two pounds of loaf sugar, pulverized: place a layer of the turnips in a bake-oven, then a layer of the sugar, and so on alternately—then cover it tight and place it over a slow fire, for three hours; then strain it, and bottle for use. Dose: one table-spoonful, three times a day. Covering the chest with a jacket of glazed cloth spread with the Liniment, as recommended in some other cases, has effected a cure in many instances when all other means had failed. It has been with much diffidence that we have published some of the results of experiments made with our remedies in cases of consumption. We never have spoken confidently in this matter, until after we had treated a large number of cases, which had been given up by all orders of physicians as incurable. These favorable results, together with testimonials from almost every section of the United States, vouched by physicians, clergymen, and gentlemen, of undoubted veracity, have induced us to publish the most successful practice b}- which patients, laboring under pulmonary complaints, have been relieved. COUGH. 131 COUGH, Is a deep inspiration of air, followed by a sudden, violent, and sonorous expiration, in a great measure involuntary, and excited by a sensation of the presence of some irritating cause in the lungs or windpipe. The organs of respiration are so constructed, that every forcing substance, except atmospheric air, offends them. The smallest drop of water, entering the windpipe, is sufficient to produce a violent coughing, by which the organs labor to expel the irritating substance. A similar effect is produced by inhaling smoke, dust, etc. The sudden expiration of air from the lungs, is produced by the violent contraction of the diaphragm, and the muscles of the breast and ribs. These parts are thus affected, by a sympathy with the organs of respiration, which sympathy springs from the connection, of the nerves of the different parts. The sen- sation of obstruction or irritation, which gives rise to cough, though sometimes perceived in the chest, especially near the pit of the stomach, is most commonly confined to the tra- chea, or windpipe, and especially to its aperture in the throat, termed the glottis; yet this is seldom the seat of the irritat- ing cause, which is generally situated at some distance from it, and often in parts unconnected by structure or proximity, with the organs of respiration. Of the various irritations which give rise to cough, some occur within the cavity of the chest; others are external to that cavity; some exist even in the viscera of the pelvis. Of those causes of cough which take place within the chest, the disorders of the lungs them- selves are the most common, especially the inflammation of the mucous membranes, which excites the catarrhal cough, or common cold. This disease is generally considered unim- portant, particularly if there be no fever connected with it. But every cough, lasting longer than a fortnight or three weeks, is suspicious, and ought to be medically treated. An- other common cause of cough which has its seat in the lungs, 132 DISEASE AND ITS TREATMENT. is inflammation of those organs, whether in the form of pleu- risy or peripneumony. These diseases do not differ very essentially, except in violence and extent, from the acute catarrh, but are more dangerous, and more rapid in their pro- gress; and the constitution is excited to a highly febrile con- dition. Even after the acute state of inflammation may have subsided, a cough, attended with extreme danger, sometimes continues to be excited, by collections of pus, or abscesses, which ensue in the substance of the lungs, and either termin- ate in consumption, or suffocating the patient by suddenly bursting; more rarely the pus is discharged gradually from a small aperture, and the patient recovers. In such cases, the fever, originally acute, is converted into a hectio, with daily chills, succeeded by heat, and flushing of the face, night sweats, and emaciation. Another frequent origin of cough, is the rupture of some of the blood-vessels of the lungs; and the consequent effusion of blood into the cells, which is expelled by the cough that its irritation excites, constituting what is technically termed hemoptoe, hemoptysis, or spitting of blood. When the vessels of the lungs are thus ruptured, they seldom heat readily, but degenerate into ulcers, which pour out a purulent matter; and, by this discharge, the vital powers are gradually worn down and destroyed. This is a common source of consumption, or phthisis pulmonalis. A cough is excited; and the same fatal disorder is also induced, by the existence of tubercles in the lungs. These are little tumors, which gradually inflame and ulcerate, and produce the same consequences as the ulcer- ations from hemoptysis. Calculi, or stony concretions, are sometimes formed in the lungs, and the irritation which they produce necessarily excites a cough, which is liable to ter- minate in consumption. There is yet another source of irritation within the lungs, of which cough is an attendant, namely, an effusion of serum into the parenchymatous substance of the lungs, or into the cellular membrane, which connects the cells and blood-vessels together. This has been called anasarca pulmonum, or COUGH. 133 dropsy of the lungs, and is marked by great difficulty of breathing, with a sense of weight and oppression in the chest, occasioned by the compression of the air cells and vessels by the accumulated water; hence so great irregularity of pulse, frightful dreams, imperfect sleep, etc., are among its symp- toms. Inflammation of the heart, and of the pericardium, or membrane surrounding it, is also accompanied by cough, and other symptoms not easily distinguishable from those of pleurisy and peripneumony. Where a cough is caused by disorders of parts external to the cavity of the chest, it is generally dry, as the irritating cause is external, and not any obstructing matter in the lungs themselves. Disorders of the viscera of the abdomen, especially of those which lie in con- tact with the diaphragm, frequently induce a cough. A short dry cough invariably attends inflammation of the liver, whether acute or chronic, and accompanies the various tuber- cular and other obstructions in that organ. Hence inflamma- tion of the liver is not unfrequently mistaken for inflammation in the lungs; and, in some of the chronic diseases of the liver, the cough is occasionally complained of as the most urgent symptom. The presence of pain in the right side, shooting up to the top of the shoulder, the dryness of the cough, and pain, enlargement, hardness, or uneasiness on pressure below the ribs of that side, will afford the best means of distinguish- ing whether a disease of the liver is the origin of the cough. Disorders of the stomach are, also, often accompanied with a cough of the same dry and teasing nature, especially when that organ is over distended with food, oris in the opposite condi- tion of emptiness. A short cough, is, therefore, a frequent symptom of indigestion and hypochondriasis, or of that weak- ness of the stomach which is popularly termed bilious. In short, there is scarcely any one of the viscera, in the cavity of the abdomen, the irritation of which, in a state of disease, has not excited cough. Disorders of the spleen, pancreas, and even the kidneys, have all given rise to this symptom; and external tumors, attached to them have had the same ef- fect. Any distention of the abdomen, which, by its pressure 134 DISEASE AND ITS TREATMENT. upwards, impedes the descent of the diaphragm, and conse- quently the expansion of the lungs, occasions cough. Thus, in the ascites, or dropsy of the belly, the water—in tympan- ites, the air—in corpulency, the fat in the omentum—and, in pregnancy, the gravid uterus—all have the effect of exciting cough in many constitutions. The variety of causes from which coughs may arise, must convince every reader of the absurdity of attempting to cure all kinds of coughs by the same remedy. TREATMENT. Most of the directions in cases of consumption which are recommended in this work, will apply to coughs generally. We have known coughs of short duration cured by a few ap- plications of our Cough Liniment about the throat, breast, between the shoulders and to the bottoms of the feet. This mode of cure is much facilitated by administering our Dia- phoretic Drops. But after the cough has become seated, it is necessary to give the Pectoral Tincture as an expectorant and sometimes as an emetic. Whoever understands our mode of treating pulmonary complaints will not be at a loss to adopt our remedies in coughs. The great object in this disorder will generally be accomplished when the obstructions are re- moved. Little more is necessary than Tonics to restore the diminished strength of the patient. RHEUMATISM; A Disease, attended with sharp pains, which has so much resemblance to the gout, that some physicians have considered it not an entirely distinct disease; although they are by no means to be confounded. Rheumatism is distinguished into acute and chronic. The former is of short continuance, and either shifting to different parts of the body, or confined to a particular part; in the lat- ter case, it has a tendency to pass into the chronic, unless RHEUMATISM. 135 properly attended to; it is often attended with fever, or some- times comes on in the train of a fever, This combination of rheumatism with fever is called rheumatic fever, which is considered by physicians a distinct species. Chronic rheu- matism is attended with pains in the head, shoulders, knees, and other large joints, which at times are confined to one particular part, and at others shift from one joint to another, without occasioning any fever; and in this manner the com- plaint continues often for a considerable time, and at length goes off. No danger is attendant on chronic rheumatism; but a person having been once attacked with it, is ever afterwards more or less liable to returns of it. Neither is the acute rheumatism frequently accompanied with much danger. The acute is preceded by shivering, heat, thirst, and feeble pulse; after which the pain commences, and soon fixes upon the joints. The chronic rheumatism is distinguished by pain in the joints, without fever, and is divided into three species: lumbago, affecting the loins; sciatica, affecting the hip; and arthrodynia, or pains in the joints. The acute rheumatism mostly terminates in one of these species. Rheumatism may arise at all times of the year, when there are frequent vicissi- tudes of the weather from heat to cold, but the spring and autumn are the seasons in which it is most prevalent, and it attacks persons of all ages; but very young people are less subject to it than adults. Obstructed perspiration, occasioned either by wearing wet clothes, lying in damp linen, or damp rooms, or by being exposed to ccol air when the body has been much heated by exercise, are the causes which usually produce rheumatism. Those who are much afflicted with this complaint, are very apt to be sensible of the approach of wet weather, by finding wandering pains about them at that period. Rheumatism usually affects only the external mus- cular parts; but it has sometimes been known to affect the internal parts, especially the serous membranes, the pleura, the peritoneum, the dura mater. J 36 DISEASE AND ITS TREATMENT. TREATMENT. The forms of rheumatism are so various—the appearance so different in persons of different habits, that it is no easy matter to give special directions for the treatment thereof. Much must depend on circumstances, which are so various, that we find great difficulty in directing and adapting all the modes, in which our remedies are susceptible of being suc- cessfully applied. In common cases of rheumatism, pains in the joints of short duration, a iew applications of the Rheu- matic Liniment will generally cure. If of longer standing, and there be wandering pains, we have known the patient cured by one full application over the whole body, taking the Diaphoretic Drops freely, and herb tea, covering up warm in bed, with hot bricks to the feet and sides, and keeping in a profuse perspiration for two hours. Perhaps it may be ne- cessary, in some of these cases, to apply the Liniment a few times afterwards, in order to prevent a recurrence. In chronic rheumatism of long standing, the disease is by no means so easily subdued. In addition to the above treat- ment, we find it sometimes necessary to take internally, for a length of time, our Vegetable Syrup and Alterative Drops; wear plasters spread with the Liniment over the region of the pain; and frequently, it is necessary to use so much Liniment on the plasters as to cause an abraded surface—and still continue the Liniment. We also wash the affected parts with the Diaphoretic Drops. Make use of the saline bath frequently. Wash off with soap suds, and use the flesh brush freely. Sometimes we give an emetic of the Pectoral Tincture. We are careful to keep the bowels open by cathartics, if necessary. We fre- quently give our Essence of Life, and in some extreme cases, the Nerve Sanative is of much importance, especially if there be any cramps in the stomach. If there be paroxysms of fever, we reduce them with our Fever preparations. Some- RHEUMATISM. 137 times we steam the affected limbs with bitter herbs, and at others, we sweat the patient with burning alcohol, in which salt has been dissolved. We have cured many extreme cases, after many months' continuing to make the above applications every day. When the system is very torpid, we have introduced two ounces of Liniment into the system, daily, for more than a month, and found the most decided advantage therefrom. 18 CHAP. IV. DYSPEPSIA. Dyspepsia—difficulty of digestion. The strict etymology of the term implies an imperfect, or disordered condition of the functions of digestion. Systematic writers, in their artifi- cial arrangements have been not a little perplexed to find an appropriate location for this affection, and this difficulty must exist whilst symptoms, which are always fluctuating, are ad- mitted into systems of nosology, as the elements of nomencla- ture and arrangement. From the same circumstances, differ- ent symptoms of the affection have received the character of separate disease, as apepsia, bradypepsia, anorexia, cardialgia, etc. These are no more than different grades in the symp- toms, or varieties of the affection, and are not different dis- eases. The disorder of the digestive function is the most frequent and general of the ailments that afflict man in the civilized state. All classes and all ages suffer from its attacks. Few are so happy as to pass through a life of ordinary duration, without undergoing a protracted struggle with this malady, and experiencing its torments. Let it once be fully estab- lished, and the comfort of existence disappears, to be regained, in most cases, tediously, and at the price of the most ascetic self-denial. The greater prevalence of dyspepsia, or indiges- tion, in modern times, arises from the more frequent injury done to the stomach and its functions, directly, by the habits of luxurious indulgence, which have been exceedingly in- creased and extended; and, indirectly, by the multiplication of intellectual and moral agitations, through an extension of the commercial and financial operations of society, the greater 140 DISEASE AND ITS TREATMENT. activity and employment of the mental faculties, and by the augmentation of political, social and individual reverses. Something, too, is to be ascribed to the mere change of names. We call that dyspepsia now, which formerly, was termed liver disease, bilious disorder, etc. A large proportion of the discomfort produced by this malady arises from an ignorance of the digestive functions, leading to their abuse and premature derangement, and may be obviated, to a great extent, by instruction as to the nature < of these functions, and their natural exercise. A general view of the digestive organs and functions is therefore requi- site to an understanding of their disorders, the means to pre- vent, and the methods of remedying them. All organized or animated beings hold their existence under the condition of renewing incessantly, the elements of their composition, by an appropriation to themselves of exterior matters. Simple animals find, in the medium wherein they live, and from which they directly receive them, the princi- ples serving for their composition. The decomposition of animal and vegetable matter in the soil prepares the aliment or nutritive principle of vegetables, which, being held in solution by water, is absorbed by their roots. In all these beings there are no digestive organs or functions. The prepa- rations of their nutriment is effected by physical operations exterior to themselves, and over which they have no control. In the higher and more perfectly organized beings, as in man, the case is very different. Nature does not present to them the nutritive elements in a state fitted for introduction, at once, into the interior organism, and for employment in its composition. Their aliments consist of the nutrive principles in a compound state, intimately combined with other substan- ces, from which they require to be disengaged. This is ac- complished by the animal itself, which is provided with espe- cial organs, or apparatus and functions for this purpose. Di- gestion then consists in the disengagement of the nutritive elements from their combinations, and their reduction to the molecular state, thus preparing them for introduction into the DYSPEPSIA. 141 Vessels, and for diffusion throughout the organism, to subserve the purpose of its composition. It is a process analogous to the decomposition of the aliment of vegetables in the soil, and is affected, like all decompositions, by analogous or chim- ical operations. In this class, the procuring of the aliment is the act of the animal, depending on its voluntary powers, and is controlled by a great variety of circumstances, affecting the quantity and quality of the food. The organs composing the digestive apparatus in man, are numerous. They arc the mouth, armed with teeth, for me- chanically breaking down the food by mastication; the saliva- ry glands, furnishing a fluid intimately combined with the food, in mastication, and collected in the stomach, which is its reservoir; the pharynx, a muscular and membranous bag, for the reception of the masticated bolus from the mouth; the oesophagus, a muscular and membranous tube, for con- ducting the bolus into the stomach; the stomach, a muscular and membranous bag, or enlargement of the alimentary canal, secreting a fluid or fluids, and a reservoir of the salivary and other secretory fluids of the interior surfaces. In the stomach the food is subjected to the decomposing process, until re- duced to a pulpy mass, called chyme, consisting of the nutri- tive and innutritive elements, in a state of mechanical mix- ture. Then follows the duodenum, or second stomach, in which the chymous mass is submitted to the action of the biliary and pancreatic fluids, and in which the nutritive ele- ments begin to separate from the innutritive matters, and to be absorbed by the lacteals, the roots of the animal economy. Afterwards we find the liver and pancreas, furnishing bile, and a species of saliva, which are mixed with, and act on the chyme in the duodenum; the jejunum and ileum, or small in- testines, in the course of which the separation, begun in the duodenum, is completed, and nearly the whole of the nutri- tive principles forming chyle, are absorbed; and, lastly, the large intestines, a reservoir for all the excrementitious prin- ciples, and which, in it, are converted to faeces. The whole of these organs compose the apparatus of digestion, but all 142 DISEASE AND ITS TREATMENT. are not of equal importance. The stomach and duodenum are the most eminent organs, and those whose condition ex- ercises the greatest influence over the powers of digestion. The different parts of this apparatus, are intimately connected, and a natural state of each of them, and a due exercise of the functions of each, are essential to the healthy, undisturbed performance of digestion. This connection is maintained through the ganglionary system of nerves, which not only unites these organs together, but combines them with all the congeries, appropriated to the perfect elaboration of the nu- tritive and sustaining principles in the economy. The sto- mach is the center of the digestive apparatus, and may be re- garded in nearly the same view, for the whole of the organs connected with individual nutrition. It owes this character to its intimate union with the great solar plexus, the center or brain, if it may be so termed, of the ganglionary system, regulating the nutritive functions. It is also immediately asso- ciated with the brain, through the medium of the eighth pair or pneumo-gastric nerves, and thus is placed in relation with the exercise of the moral and intellectual faculties. The stomach is, consequently, liable to be disordered in its func- tions, by violent impressions upon these faculties, as these also in their turn are liable to be affected by the disordered condi- tion of the stomach. It is necessary to have these diversified, connections pointed out, in order to possess a clear under- standing of the numerous and very different sources, from which disturbances arise to the progress of digestion. A few words will now be necessary as to digestion itself. All substances are not fitted for aliment, nor susceptible of digestion. Food is intended for the renovation of the body. It must consist of the same elements as those which constitute the animal structure, and be capable of becoming organized and vital. It must, then, contain at least three elementary animal principles—hydrogen, carbon, and oxygen; and much of it also contains a fourth—viz: azote. These elements form secondary compounds, in which state alone they consti- tute aliment: such are albumen, fibrin, gelatin, osmazome, oil, DYSPEPSIA. 143 engan, farina, mucilage, and other animal and vegetable com- pounds. In all these substances, the molecules are easily sep- arable, without being chimically decomposed; and this is one of the primary requisites of digestibility, to effect which is the chief object of digestion. The masticated and insalivated food passes into the stomach. Here it is macerated in the saliva collected in the stomach, and in the proper liquid se- creted by the villi of the gastric mucous membrane, at a tem- perature of 104° Fahr. This liquor is called gastric juice. Its true nature is not accurately determined; but, as far as dis- coveries of it have been made, it resembles saliva, mixed with a small portion of lactic or muriatic acid. The stomach, in a healthy state, always contracts on its contents, so that, in diges- tion, its parietes are always in contact with the food. During digestion, the stomach has a constant vermicular motion, its muscular fibers contracting successively, from the smaller to the larger end. The food thus agitated, acquires a rotatory movement, and is mingled with the fluids of the stomach. In a short time, the change to be accomplished in the stomach commences; the food, becoming pulpy and thin, is reduced to a semifluid, of a light, grayish color. From the uniform pressure of the stomach, the solid and most resisting portions are forced into the center, while the digested and more fluid matter is found on the surface, and is gradually carried, by the contraction of the muscular fibres, into the duodenum. William Philips, and others, have been led to suppose, from this circumstance, that the food in contact with the parietes of the stomach, was alone digested; but it is a mere physical result, as uniform pressure in every direction, on a mass of different consistency, will always drive the most fluid to the circumference. The pulpy, grayish substance, resulting from the stomachic digestion, is called chyme. When examined with the micro- scope, the writer of this article has always found it to consist of an immense number of transparent globules, of various sizes, intermixed with undissolved fragments of the fibers of the alimentary substance. When food is masticated, and 144 DISEASE AND ITs TREATMENT. macerated for a few hours in simple saliva, he has found it to present exactly the same appearances as the chyme of the stomach. The digestion of the stomach, he infers from his experiments, is not a decompositio?i of the alimentary matter, but is a simple disintegration of it into its com- ponent molecules, the animal character remaining un- changed. The chyme, having passed into the duodenum, meets with the pancreatic liquor and the bile. What are the positive changes induced by these fluids, is not accurately known. The acids of the chymous mass are neutralized by the alkaline principles of the bile, the picromel and coloring matter of which appear to coalesce with the unassimilative principles of the food, and assist in their conversion into faeces. A chimical modification in some of the alimentary elements, may also be effected. It is certain that chyle, or the nutritive principles of which blood is formed, does not appear in the lacteals until after the action of the bile and pancreatic fluid on the chyme, the product of the stomachic digestion. The action of the stomach on the food, is that usually designated as digestion, and it is the derangement of this process that is usually expressed by the term dyspepsia. The process accomplished in the duodenum, is also a true di- gestion, and the symptoms arising from its disordered state, are confounded with those of the stomachic digestion, in the general account of dyspepsia. From this sketch of the function of digestion, it is evident that its most important agents are, 1st, the fluid secreted in the stomach; 2d, the contractile movements of the stomach, keeping the alimentary mass in constant agitation, mixing it with the fluids as they are secreted, and removing the portion digested, or reduced into chyme; 3d, the application of the biliary and pancreatic fluids to the chyme, in the duodenum; 4th, the contractile movements of this viscus. Most of the derangements of the digestive functions may be traced imme- diately to a departure from a natural state of some one or more of the above requisites of digestion. But this devia- tion from the natural order is, itself, an effect. The secretions DYSPEPSIA. 145 are products of organs, and all excitement of the secretory organs beyond the range of healthy action, causes a vitiation of the secretion, or its total suspension. This action of the organ, diminished below the physiological range, is attended with other vitiations of the fluid, or the cessation of its se- cretion. Indigestion, or dyspepsia, is a consequence of both these conditions of the organs furnishing the fluids of diges- tion. Digestion is a very stimulating process: all functional actions are exciting. The increased demand for secreted fluids renders an augmented action, and an increase of blood in the furnishing organs, necessary, for their production. The presence of the food, drinks, etc., in the stomach, add to the stimulation of digestion. If the stomach of an animal be examined while in the act of digestion, its mucous membrane is found to be of a diffused scarlet color. The movement of the stomach essential to digestion depends on its nervous com- munications, and especially on the integrity of the eighth pair of nerves. When these are divided, the stomach and oesophagus are paralyzed; the food is no longer agitated and mixed up with the digestive fluids, and it often regurgitates from the stomach into the oesophagus. This fact proves the influence of the contractile motion of the stomach in the act of digestion. The ganglionic nerves are not less important, though their specific influence cannot as readily be determined. But in many cases of disease of ganglions, vomiting, eructa- tions, pain in the gastric region, and impaired digestion, are accompanying symptoms. Through the nervous system, the function of digestion is exposed to numerous disorders from moral impressions, especially those of an agitating character. From the preceding principles, it is evident that dyspepsia or indigestion is not, properly speaking, a disease, but rather a symptom, indicative of diseases of the digestive apparatus, themselves very various and even opposite in their character. No specific treatment can, therefore, be laid down for the cure of dyspepsia, but each case requires to be managed according to its peculiar cause and nature. The organ of the digestive apparatus most frequently productive of dyspeptic symptoms 19 146 DISEASE AND ITS TREATMENT. is the stomach, and the most usual cause of dyspepsia is its irritation and inflammation. The stomach is more liable than any other organ to these states, from its direct exposure to so many irritating influences, and its intimate sympathetic com- munications, which make it participate in the irritations of almost every other organ. The sub-acute and chronic forms of gastric irritations and inflammation, the signs of which have only of late been fully appreciated, are the disorders that, in seven or eight cases out of ten, are termed dyspepsia. Hence dyspepsia so frequently succeeds to febrile diseases, especially when treated by emetics, drastics, and the improper use of tonics and stimulants, which, although the patient may escape the fever, leaves him a victim to the chronic, disorgan- izing and perturbating irritations of the gastric mucous mem- brane. Hence, too, dyspepsia almost inevitably follows con- tinued abuse of the digestive functions, from too highly sea- soned or too abundant food, and stimulant drinks. The con- stant stimulation of the stomach finally becomes pathological or morbid. The simple prolongation of the functional ex- citement essential to digestion, continued from meal to meal, without permitting the stomach to revert to a state of repose, is sufficient to constitute a morbid condition. All functions, for their perfect performance, require alternate periods of re- pose and activity. Incessant action irritates, inflames, and finally disorganizes the structure of the organs. A second condition of the stomach, productive of dyspep- sia, is the congestion of its mucus tissue. This may be con- fined to the stomach alone, succeeding an attack of acute gas- tritis, or following on its protracted irritation; or it may be an attendant on a general congestion of the whole portal system involving most of the abdominal viscera. Every irritation is attended by an afflux of the circulating fluids into the structure where it is seated; an afflux proportioned to its intensity and the vascularity of the structure. This gorged state often con- tinues after the subsidence of the irritation that provoked it, and prevents a resumption of the healthy functions. It is a state of passive congestion, and often exists in the mucous DYSPEPSIA. 147 membrane of the stomach, after attacks of inflammation or acute irritations, and embarrasses its digestive operations. In all the extensive irritations of the alimentary canal, especially when attended with fever, having a paroxysmal character, the great portal system of the abdomen becomes loaded with blood, and congestion of its radical vessels ensues. The functions of the viscera are then disordered, the secretions are defective, and indigestion, costiveness, and their attendant affections, are the necessary consequences. A third state of the stomach, causing dyspeptic symptoms, is precisely the reverse of the preceding. Asthenia, or dimi- nution of vitality and actions below the healthy degree, occa- sionally takes possession of the stomach. Its circulation is then deficient, its secreted fluids are defective in quantity or quality, its sensibility is impaired, and digestion is imperfect. It is not probable that gastric asthenia is ever primitive. It succeeds to previous irritation, and is often occasioned by irritation in other organs. All the preceding conditions form a first class of dyspeptic diseases, which, depending entirely on the stomach, may be termed gastric dyspepsia. This class embraces three spe- cies. A second class of dyspeptic diseases is connected with the duodenum and its functions. This viscus, similarly consti- tuted to the stomach, is subject to the same morbid alterations. Its mucous membrane is the seat of irritation, in its various grades, and productive of its usual consequences—augmented irritability, sensibility, perversion of secretions, vitiation of structure, and disorder of function. Duodenic irritation most commonly accompanies gastric irritation, and the symptoms of the two are blended together. It exists, however, in many instances independently, and then manifests particular symp- toms, which are often termed dyspepsia. It is, more espe- cially, the chronic irritations of the duodenum, that pass for dyspepsia. It is not probable that congestion, or asthenia ever affects the duodenum exclusively, to the detriment of its functions. When these states prevail, it is in conjunction 14S DISEASE AND ITS TREATMENT. with similar conditions of the whole digestive apparatus. At least, we have no knowledge of these states limited to the duodenum. A third class of dyspeptic diseases depend on those organs which furnish nerves to the digestive viscera. The gangli- onic system of nerves, distributed on each side of the spine, from the head to the pelvis, transmits nerves to all the organs connected with the nutritive function. The stomach espe- cially, is largely supplied from the solar plexus, and it re- ceives, likewise, numerous nervous filaments from the pneu- mo-gastric, placing it in connection with the functions of re- lation. The offices of the ganglionic system, are not ascer- tained with precision. It is, however, well determined, that diseases of the ganglions, disorder the functions of the viscera to which they transmit nerves. Hence arises an order of dyspeptic symptoms, independent of any immediate affection of the stomach, but occasioned by disease in the great solar, or other neighboring plexus. The disorders of the digestive functions, from this cause, are various. The sensibility of the stomach is sometimes greatly increased, constituting gas- tralgia. At other times, the secreted fluids of the stomach are morbidly acid. The stomach appears, in other cases, to be partially paralyzed, and the peristaltic movements, neces- sary for the admixture of the food with the gastric fluids, and the continuous passage of the chyme into the duodenum, are suspended. At the same time, considerable quantities of flatus collect in and distend the stomach, preventing its action on the food. Mechanical manipulation of the abdomen, and particularly of the epigastrium, after a meal, becomes a sub- stitute for the natural motion of the stomach, expels the wind, and facilitates digestion, that would otherwise be laborious and painful. Dyspepsia, or indigestion, from this analysis of its modes of production, is seen not to be a disease of uniform character, and depending on an identical state of the digestive organs. It is attached, as a symptom, rather to a variety of conditions, each of which requires to be managed in its appropriate mode. DYSPEPSIA. 149 It is not possible that it can be remedied by any one general mode of treatment, or by any set of specific remedies. The most common causes of dyspepsia, are excesses of va- rious kinds, especially in quantity of food. Most individ- uals, in this country, err in this respect. Meat at three meals, daily, can be borne only by the most robust frames, and by hard laborers. Persons of a sedentary life, require less nutri- ment; the economy makes less demand on the stomach for supplies; and if it be compelled then to labor, it is at its own loss. Exercise, or the expenditure of the nutritive elements by the economy, and the quantity of food to be digested, must be proportioned to each other, for the preservation of health, and the due vigor of digestion. The food, by being render- ed tender and pulpy, is reduced to chyme in a shorter period, with a smaller expenditure of the secreted fluids, and less ex- citement of the stomach, than when it is not properly con- cocted. The art of long and healthy living, will depend on a perfect system of cooking, and a rational mode of eating. The powers of the stomach differ in individuals, as much as the force of their muscles; and each one must adopt a mode of nutrition, both as to quantity and quality of food, suitable to the wants of his economy, and the digestive capacity of his stomach. The quality of food is a frequent cause of dyspepsia. Tough and badly dressed meats, and crude vege- tables, are among the prominent causes of this affliction; as are also hot bread and cakes, heavy and fresh bread, and the daily use of hot coffee for breakfast. In enumerating the most common causes of dyspeptic symptoms, we ought not to omit the frequent exacerbations of malevolent passions, as anger, hatred, envy, jealousy, and, what is not often suspected, excessive indulgence and abuse of the venereal propensity. Another fruitful source of the digestive disorders, is found in the employment of emetics, and in a frequent resort to saline or drastric cathartic medicines. When a constipated habit prevails, it should always be overcome, if possible, by a laxative regimen, and the acids of purgatives should be cau- tiously and rarely invoked. 150 DISEASE AND ITS TREATMENT. TREATMENT. Though it may not be expected that our general directions will be competent to meet the different forms of this disease, in all cases, the ingenuity of those who are acquainted with our remedies will, in most cases, suggest the means of sup- plying the deficiency, according to the nature of the case. In all cases, we 1st. Apply the Stimulating Liniment, with much friction, to the stomach; wear a plaster of the same over the whole region of the liver, and down as low as the navel, renewing the same once or twice a day, and at each renewal rub the Liniment in with the hand, as first directed. If the nerves be affected, apply the Nerve Liniment on the whole length of the spine, and on the top of the head. Wash the whole body with salt and water, applied with a flesh brush (stiff as can be borne) every day. 2d. In more severe cases, wash the whole body with soap and water, applied with a flesh brush, wipe dry, apply the salt and water, (salt as it can be made,) rub dry, and then apply the Stimulating Liniment over the whole body, once every day, with much friction; apply plasters to the bottoms of the feet; wear the plasters as first directed, also, and repeat the washing off with soap suds, etc., every third day. Take our Vegeta- ble Syrup, Alterative Drops, and Essence of Life, according to directions. To prepare the system for the reception of the Liniment in the first instance, (after washing off and applying the Liniment as directed under this head,) place warm bricks to the sides, and bottoms of the feet, when in bed, and use our Diaphoretic Drops freely, as directed. 3d. In extreme cases, where a healthy action of the system is not readily produced by the above directions, and where the liver has become extremely torpid, we use a salt bath to good advantage, and immediately apply a plaster of glazed cloth, in form of a vest, covering the whole chest, which is worn night and day, renewing the Liniment and using fric- tion, as above directed. MENTAL DERANGEMENT. 151 To apply the salt bath, take a gill of alcohol, and add as much fine salt as will dissolve in it, set it on fire, under a chair, on which let the patient sit, covered with a blanket to his neck, and take of the Diaphoretic Drops according to di- rections: this will cause a copious perspiration, without any diminution of strength; after which, wash off with warm salt and water, using the brush, and the system will readily re- ceive the Liniment. In these affections, the bowels generally become consti- pated: the exhibition of our Vegetable Syrup, will in most cases overcome the difficulty; but should~it not be sufficient, a gentle cathartic may be administered. Note.—When the lungs are in any degree affected, the Consumption Liniment should be applied to the breast, and over the region of the lungs, with plasters: so, when the pa- tient is affected with rheumatic symptoms, or pains, accom- panying this disease, the Liniment for rheumatism should be applied over the parts thus affected. A large number of cases, and apparently of very alarming character, have been relieved and cured by the use of our remedies as first directed, and it has generally been found to be all that was necessary for the complete cure of dyspepsia. In some cases, relief is very soon gained; in others, it has re- quired time and perseverance; but, when the disease has evi- dently made a deep impression upon the system, especially when it has been accompanied with nervous or rheumatic affections, and a state of convalescence is not soon produced, we resort to the other remedies and modes of application, as given under the 2d and 3d heads of direction; a persevering use of which we have never known to fail of fully accom- plishing the desired object—that of sound health, and vigor. MENTAL DERANGEMENT —INSANITY. By these general terms, we understand every form of in- tellectual disorder, whether consisting in a total want or aliena- 152 DISEASE AND ITS TREATMENT. tion of understanding, as in idiocy, or in only slight aberra- tions of the faculties. Medical writers have adopted different systems of classification, in their treatment of this subject; but perhaps the most convenient, is that which comprises all mental diseases under the four heads of mania, melancholy, demency or fatuity, and idiocy. Lunacy, in its proper sense, implies an influence of the changes of the moon on the state of the mind or body, of which modern science cannot recog- nize the operation. It is true, that many diseases are periodi- cal; and it is not improbable, that paroxysms of violence among insane persons, may be really increased at the time of a full moon, by the effect of the shadows of clouds, and other objects, as ghosts are generally seen by moonlight; but any other lunar influence, neither experience nor science can dis- cover. The causes of insanity are divided, by modern writers, into physical and moral. Every excess of passion—joy, grief, anger, fear, anxiety, etc., may become a moral cause of in- sanity. Great political or civil revolutions have always been observed to be attended with numerous cases of mental de- rangement. Pinel observed this phenomenon in France, after the revolution of 1789; and Doctor Rush describes similar effects in the United States, after the war of the revolution. Strong religious excitement often produces similar results, although, in many cases, religious enthusiasm is only a form of the malady, and not a cause. Madden, (Travels in Egypt, Nubia, etc., 1830,) states that insanity is rare among the Mo- hammedans, and attributes it to their consoling belief in the certainty of their salvation. Doctor Rush thinks that the disease is more common among civilized communities, than with savages, on account of the greater influence of moral causes on the former. The physical causes of insanity are various, and numerous; diseases of various kinds, and of dif- ferent organs; bodily injuries, or wounds; excessive indul- gence in eating, drinking, and other sensual pleasures; priva- tion; exposure to extreme cold, or heat, etc., are among them. Insane persons are often, however, in good health; and dis- MENTAL DERANGEMENT. 153 section does not always detect a disordered condition of the organs. Philosophy is not sufficiently acquainted with the mutual action and reaction of the body and the mind on each other, to decide how far the disordered state of the one is consistent with the sanity of the other; nor is it certain that there is any one organ, or function, which must be diseased, to affect the mind. Climate, age, occupation, and sex, are often mentioned as causes influencing insanity. But climate does not appear to be an exciting cause, although the moral, civil, religious, or physical condition of a nation, may have rendered the disorder more frequent in some countries than in others. The seasons, however, appear to exercise an influ- ence, and it is generally observed that the cases of insanity are most numerous in the hottest part of the year. Suicides are most frequent when the thermometer is above 84°. Al- though many circumstances, both physical and moral, appear to render the female sex more liable to insanity, it does not appear that the number of insane females is greater than that of males; drunkenness being more prevalent among the latter, may be one cause of this. In both sexes, the most active period of life, from thirty to forty, presents the greatest num- ber of cases. In regard to occupation, sufficient data do not exist to show that there is any decided predominance of cases in any particular employment. Idiocy is either a congenital, or an acquired defect of the intellectual faculties, or, as Pinel defines it, an obliteration, more or less absolute, of the functions of the understanding and affections of the heart. Congenital idiocy may originate from a malformation of the cranium, or of the brain itself; the senses are often wanting, or defective, and life is com- monly of short duration. Acquired idiocy proceeds from mechanical injury of the cranium, or from an injury or a disease of the brain; from excess in sensual indulgences, in- temperance, fatigue, and from moral causes. In some, the senses may be partially affected, or quite destroyed; and life often continues to old age. Absolute idiocy admits of no 20 154 DISEASE AND ITS TREATMENT. cure; but it should not be too hastily concluded that a patient is in this state. The term demency is applied to a complete or partial hebe- tude of individual faculties, particularly those of association and comparison, producing confusion of thoughts, loss of me- mory, childishness, a diminution or loss of the powers of vo- lition; it differs from idiocy, in being curable. Persons being reduced to this state, exterior objects make but weak impres- sions on them; the sensations are therefore feeble, obscure, and incomplete; the patient does not form a correct idea of objects, nor compare associate or abstract ideas. It is often merely an attendant of other diseases, or other forms of in- sanity, and is frequently quite temporary, though it often be- comes permanent. Mania (madness) is a species of mental derangement, characterized by the disorder of one or several of the facul- ties, or by a blind impulse to acts of fury. Adults are the principal subjects. A nervous temperament, an irritable con- stitution, predispose to it. Females are more exposed to it than males, particularly at the period when menstruation be- gins or ceases, during pregnancy, and after delivery. Violent emotions, a dissipated life, excess in any indulgence, some- times produce it. This disorder of the intellectual faculties, is manifested by extravagant, gay, gloomy, or furious emo- tions; the gestures and words seem automatic. Sometimes the conversation is rational, but the patient bursts out at in- tervals, into paroxysms of rage, attacking everything which he meets; the moral affections also seem deadened, and the most ferocious hatred is displayed towards the most natural objects of love. It is sometimes cured, but sometimes re- mains stationary, and sometimes is converted into demency. Repeated bleeding, hellebore, cold water poured upon the head, scouring, and other means of terror, were formerly em- ployed as remedies. At present, solitude, warm baths, low diet, etc., are more commonly applied. Some dark or mourn- ful ideas occupy the mind exclusively, so that, by degrees, it becomes unable to judge rightfully of existing circumstances, MENTAL DERANGEMENT. 155 and the faculties are disturbed in their functions. The pow- ers of the soul become weakened, we might say crippled. If these feelings are allowed to attain a hight, at which the pow- er of self-control is lost, a settled gloom takes possession of the mind—consciousness, however, may still continue; the person knows his state: but if conciousness is also lost, if this state becomes continual, the melancholic patient is insensible to the world around him; he only lives within himself, and there only in the circle of one fixed idea. In this disordered state of the feelings, the other faculties may still continue to act, although the mode and result of their operation will ne- cessarily be influenced by the existing disease. There may be reflection in the actions of the patient, but the reflection proceeds from false premises. Several kinds of melancholy are distinguished; the distinc- tions are founded, however, mostly on the cause of the dis- ease. A very common cause of melancholy is love. He who loses the great object of his wishes and affections, which has absorbed, we might almost say, the whole activity of his soul, feels more than a jealousy at the success of a fortunate rival; existence appears to him a blank, and himself the most unhappy of men. Another frequent cause of melancholy, is gloomy views of religion. A constant excitement of the feelings, by the awful picture of the eternal punishment of sin, often produces absolute despair. The use of such means, to prepare the mind for the reception of deep religious princi- ples, has not unfrequently led to distraction and suicide. Re- peated failures in enterprises pursued with anxious zeal, may also reduce the faculties of a man so much, that he becomes wrapt up solely in the idea of his misfortune. Melancholy patients often flee from men, haunt solitary places, such as orave-yards, and are given to nocturnal rambles. The course of the disease is various; sometimes it lasts a series of years; sometimes it ceases itself, or is cured by medical aid; more frequently it passes over into other kinds of insanity, or into bodily diseases, as dropsy of the chest, consumption, dropsy in the head, apoplexy, etc. It is said that melancholy people 156 DISEASE AND ITS TREATMENT. rarely suffer from the gout, or are attacked by epidemic dis- eases. Several physical causes are enumerated, as inducing it, particularly a superfluity of black bile. Various derange- ments in the physical system tend to occasion it, as debility of the nerves, violent flow of the blood to the heart, superfluity of thick blood, etc. TREATMENT. The man who becomes a maniac is but a mere blank in society—nay, worse—for sometimes his nearest friends and bosom companions are in imminent danger from his ravings. Within half a century, much has been done by the philan- thropist in alleviating his forlorn situation; asylums have been erected; the State has contributed means to render him com- fortable ; the best regimen and management have been adopted to restore him to his right reason; and it is a pleasing reflection that in many instances these means have had a most salutary influence, and sometimes the insane is restored to his friends. While all these philanthropic institutions have been progressing, it is with much satisfaction we reflect that some- thing has been done by our remedies for the benefit of this distressed class of people. A number of individuals (under circumstances of confirmed madness) have been brought to the enjoyment of sound health and reason, by our preparations alone, without the aid of other agents.* Whatever may have been the producing cause of mental derangement, it will not be denied that the derangement of the nervous system is the cause of a continuation of the complaint. In all cases which have been treated by our remedies, just so soon as the nerves were restored to a healthy state, so soon reason has reassumed her empire. For the accomplishment of this object we have prepared a number of medicines which are admirably adapted to the restoration of those organs. Our Nerve Liniment, Ve- getable Syrup, Nerve Sanative, Essence of Life, and Pecto- ral Tincture, are all adapted to the complaint, and can be made use of in various stages of the disease, with the most decided advantage. HYPOCHONDRIASIS. 157 These remedies are well adapted tp the cure of those dis- eases which are generally attendant on a deranged state of the nerves; and it would be in vain to attempt to restore the nerves to soundness, while the cause which produced their derangement remained in the system. A peculiarly pleasing incident has thus far attended the administration of our rem- edies in cases of insanity. The relief they have gained, has been so readily manifest that on a recovery of their senses, the patients thus afflicted have become attached to the medicine, and in some instances have refused to be further treated by any other remedies. The shaving of the head and applying the Nerve Liniment to the same, to the neck, and in the ears, with the usual course of administering our remedies, as laid down in this work, is all that is necessary to be said to render the treatment success- ful by a physician of intelligence. HYPOCHONDRIASIS. This is one of the most troublesome diseases. Its seat is in the abdomen, particularly under the short ribs; but when it has increased to a certain degree, it manifests itself in the most various ways, in the whole body, as there are few dis- eases of which the hypochondriac does not at some time or other complain. He feels a pressure on the right side, and thinks it is owing to a complaint of the liver; he has pains in the breast, and immediately apprehends inflammation of the lungs; his head feels heavy, and nothing is more certain than an approaching apoplexy; he sees specks before his eyes, and a cataract is unavoidable; if the heart beats stronger than usual, a polypus in that organ is probable; and an unimportant pimple becomes the indication of inveterate ulcers; and so on. All these effects of the disease are explicable from its nature, seat, and causes. Hypochondria is a disturbance of the func- tions of the nervous system of the abdomen. Hence, the 15S DISEASE AND ITS TREATMENT. sensibility of the nervous system is morbidly heightened, but its power of action lessened. At the same time, the sepa- ration between the nervous system of the abdomen and that of the brain is rendered less complete, so that certain feelings reach the brain, and thus affect the thoughts much more than in a state of health. The disturbance in the functions of the abdominal nervous system, produces next a weakness and disturbance in the digestion, which generally produces the first and most numerous attacks of hypochondria, from which all the others originate, in proportion as the morbid sympathy extends over the whole body. Hence, first is produced spas- modic contractions under the short ribs, sometimes on one side, sometimes on the other, sometimes in the pit of the stomach; torpidity of the bowels, flatulency, inflammation of the abdomen, want of appetite, increased pressure, and gener- ally disagreeable feelings after eating. In the progress of the disease, a slow and somewhat difficult inspiration comes on, indescribable anxiety, and pain and giddiness in the head. Also, wdien the stomach is empty, this organ sometimes suf- fers pain and sickness, and vomiting takes place. For mo- ments, particularly after digestion is finished, the hypochon- driac feels easy, well, and serene; but all at once, the old com- plaints seize again upon their victim. The disturbance of the nervous system also has, as well may be conceived, a great influence upon the mind, and humor of the patient. Some- times he is melancholy, sometimes gay to an excess. Un- interruptedly occupied with the state of his body, he takes notice of every feeling, and wishes to have every trifling pain explained, considering every one as a symptom of a serious disease. For everything he wants physic. In the hours of anxiety, hypochondriacs are constantly in dread of death. Sometimes anxiety attacks them so suddenly, that they must jump up, and cannot find quiet anywhere. Sometimes me- mory leaves them, so that they cannot think of their name. In the midst of the most serious conversation, nay, even of prayers, the most ludicrous ideas or images strike them. Oth- ers, all at once, feel a desire to perform the strangest actions, HYPOCHONDRIASIS. 159 from which they can restrain themselves only with great difficulty. This deplorable disease may be occasioned by any circum- stances which disturb the functions of the abdominal nervous system, highten its sensitiveness, debilitate digestion, and les- sen the separation of the reproductive nervous system from the sensitive. Among the chief causes, are great exertions of the mind in studying, a sedentary or dissipated life, ex- cesses in exciting liquors, particularly coffee; also, want of exercise of the physical and mental powers, producing ennui. Hypochondria is, physically considered, not a dangerous dis- ease. It is true, the genuine hypochondriac believes, at least for six days in every week, that his hour is come. He passes a wretched existence, and is a real torment to his family and physician. Hypochondria can be cured but slowly. A hypochondriac must abstain from much physic, but the difficulty is to per- suade him to do so. He would often rather take ten medi- cines than one. He ought to avoid sensual indulgencies, but his irritated nerves refuse obedience to duty. He ought to master his feelings, but the body has become the governing power. He ought to take much exercise, but his indolence finds continual excuses for omitting it. He ought to observe a strict diet for years, and confidently follow the directions of his physician, but he is impatient to be cured immediately, and his most solemn promises are forgotten in a week. He would have ten physicians at once, not to follow their advice, but to quarrel with all, and to tell them that they know noth- ing of his case. Thus it happens that a hypochondriac is sel- dom entirely cured, but, after having suffered for years, he dies of some additional disease; or in very advanced age, when the irritability of the nerves is lessened, the disease still ap- pears. TREATMENT. It would be in vain to point out any one mode of treating the above complaint, as it is questionable whether the patient 160 DISEASE AND ITS TREATMENT. would be persuaded to pursue a regular course of treatment, for even one week. It is sufficient here to remark that the complaint is a ner- vous affection, affecting the whole system, to a certain extent. We will remark further, for the benefit of those thus afflicted, that our Nerve Liniment, Vegetable Syrup, Nerve Sanative, Essence of Life, and Pectoral Tincture, are all invaluable remedies, and, if used according to directions, and persevered in, will restore the nerves to strength and vigor, and a cure will be the result. HYSTERICS, Are, with women, nearly the same as hypochondriasis with men; the difference which really exists, arising from the pe- culiar character and constitution of women. This disease arises from a morbid excitement of the nervous system, and manifests itself by great uneasiness, unusual susceptibility, occasioning great trouble, often from imaginary causes, and affecting the sufferer even to tears. To these is added the sensation of a ball mounting from the abdomen, and particu- larly from the pit of the stomach, where the most important nerves concentrate, and occasioning a feeling of strangulation. From the greater susceptibility in the system of women, these affections are more universal, and appear quicker in other parts of the body, particularly in the muscles, than in men. Hence spasms of various kinds, contractions of the neck, pains in the head, fainting fits, palpitation of the heart, appear very frequently, and are sometimes so severe, that persons afflicted with them seem to be dying, These complaints were once ascribed to vapors arising from the stomach, and were called by that name. They were once very fashionable among the ladies. Women of a delicate habit, and whose nervous system is extremely sensible, are the most subject to hysterical affections; and the habit which pre- HYSTERICS. 161 disposes to these attacks, is acquired by inactivity and a se- dentary life, grief, anxiety, and various physical disorders. They are readily excited, in those who are subject to them, by strong emotions, especially if sudden. Hysterical com- plaints are best prevented, by a judicious care of the moral and physical education of girls. Men of uncommon nervous sensibility, are sometimes subject to disorders not essentially different. TREATMENT. Much less charity has generally been extended to those af- fected by this complaint, than we ought to bestow. It is evi- dently an affection of the nervous system, and whenever that system is restored to sound health, the patient becomes in- vigorated, and enjoys good health. Our preparations for nervous affections are abundantly competent to master this disease. 1st. The Pectoral Tincture may be taken, in small doses, as an alterative. 2d. The Essence of Life, in cases of fainting, is of great service. 3d. Sometimes it may be necessary to administer our Nerve Sanative, diluted in warm water, in two drop doses, twice a day. 4th. The Nerve Liniment ought to be applied on the top of the head, behind the ears, and on the neck, at least once a day, and a plaster should be worn on the breast constantly. 5th. If the feet be constantly cold, as is the case in some instances, the Stimulating Liniment should be applied to the bottoms of the feet once a day. Much attention should be paid to keeping the bowels in order, and the most simple diet should be adopted. Those few cases of this complaint which are not caused by other forms of disease, are treated of in another part of this work. 21 162 DISEASE AND ITS TREATMENT. DEPRESSED STATE OF THE MIND. Notwithstanding the uncharitableness of the world at large, for those who are afflicted with low spirits, we aver it to be a disease, occasioned principally by indigestion. Some writers believe the seat of the disease to be confined to those particular regions of the abdomen called hypochondriac, which are situated on the right and left side of the cavity, whence comes the name of hypochondriasis. The common symptoms are, acid eructations; flatulency in the stomach or bowels; spasmodic pains; costiveness; giddi- ness; dimness of sight; listlessness, and often unable to fix the mind on any thing which requires vigor of thought. The mind becomes fretful, dejected, and desponding, accompanied with a total derangement of the nervous system. The men- tal feelings and peculiar ideas that haunt the imagination, and overwhelm the judgment, exhibit an infinite diversity. The wisest and best men, who have led a sedentary life, are as subject to the affliction, as are those of the other sex, who generally possess fine talents, but are thus unfortunate by rea- son of a general derangement of their system. The causes of the complaint are, severe study, protracted to a late hour at night, in a cold room; a sedentary life; dis- solute habits; excess of eating and drinking; use of mercury; suppression of habitual discharges, or long continued erup- tions; debility of the organs within the abdomen, etc. The symptoms vary much in different patients. Whoever leads a sedentary life, and neglects to keep the feet warm, is sure to be afflicted with some or all of the above symptoms; and as a preventive, we would recommend the putting of half a tea- spoonful of cayenne into each stocking, daily. This will give action to the system, and prevent much of the evil very properly ascribed to cold feet. DEPRESSION OF MIND. 162 TREATMENT. The principal object is to remove obstructions, restore the digestive powers, and brace up the nervous svstem to a healthy action. These objects can more readily, and with greater certainty, be effected by the application of our exter- nal remedies, than by any other practice of which we have a knowledge. Our first object is to relieve the nervous affec- tion, by which all gloomy apprehensions will subside, and the patient's confidence in a cure will be much strengthened. 1st. Apply the Liniment for Nervous Affections on the top of the head, on the neck, the whole length of the spine, the inside of the arms, thighs, and legs; and if there be palpita- tions, apply the same over the region of the breast; at the same time, apply the Stimulating Liniment, on plasters, to the bottoms of the feet. This ought to be regularly repeated two or three times a day, until the nervous system is relieved. In addition to the above, the patient ought to take the Nerve Sanative and Essence of Life. 2d. Apply the Stimulating Liniment, on a plaster, to the breast; renew it once or twice a day, as the urgency of the case may require. This application will regulate the stomach with more certainty than the exhibition of an emetic, as re- lief is gained without any of the evil consequences generally attendant, in such cases, by the exhibition of large doses of strong medicine internally. Sometimes we find much advan- tage in giving the Diaphoretic Drops. Apply bricks to the feet, and cause a free perspiration. In some cases, the Pecto- ral Tincture taken in three drop doses, on loaf sugar, has produced a salutary effect; and in a very few instances have we found it necessary to increase the dose to twenty drops, so as to cause vomiting. The Vegetable Syrup is an excellent remedy. The washing off the surface of the body in soap suds and weak lye, or salt and water, will be found advan- tageous in this complaint. We also make free use of tonic bitters—eat easily digested food—exercise on horseback is serviceable—and keep from exposures to a moist atmosphere. CHAP. V. DIARRHEA, OR LOOSENESS. Diarrhea consists in copious discharges of feculent mat- ter by stool, accompanied by griping, and often, at first, by slight vomiting, but unattended either by inflammation, fever, or contagion. The presence of these, with tenesmus, (a con- tinual inclination to go to stool without a discharge,) and an evacuation of blood and purulent mucus, with hardened balls or scybala instead of natural faeces, which prevail in dysen- tery, will always enable the practitioner readily to distinguish the two diseases from each other. It is to be distinguished from cholera morbus by the discharges not being very bilious, and also by there being no vomiting of bile. In diarrhea, there is evidently a morbid increase of the peristaltic motion, which morbid increase is the effect of a variety of causes, applied either to the body in general, or acting solely on the parts affected. Of the former, may be noticed the application of cold to the surface of the body, so as to give a check to perspiration, and thereby determine the flow of blood more to the interior parts; as likewise passions of the mind, and certain diseases, as dentition, retrocedent gout, and rheumatism, fever, etc. Of the latter, may be enu- merated, first, matters taken into the stomach, and acting either from their quantity, as in the case of overcharging the organ; or from their nature, on the state of the stomach it- self, producing fermentation, as acid fruits, or oily and putrid substances, and purgative medicines. Secondly, matters gene- rated in the body, and thrown into the intestines; acrid bile, pancreatic juice, purulent matter, water in dropsy, worms, etc. Thirdly, mucous matter, poured from the mucous folli- 166 DISEASE AND ITS TREATMENT. cles of the intestines themselves, in consequence of an in- creased excretion, and producing what is known by the name diarrhea mucosa (from mucus). In diarrhea, each discharge is usually preceded by a murmuring noise and flatulence in the intestines, together with a sense of weight and uneasiness in the lower part of the belly; which cease on the discharge taking place, but are again renewed before the one which is to succeed ensues. The appearance of the stools is various; sometimes they are thinner than natural, from the admixture of a larger quan- tity of fluid, poured out by the exhalents of the intestines, than common; sometimes they are slimy, and sometimes they are green, when first discharged; sometimes they are evacu- ated of a yellow color, but.become green on exposure to the air; and now and then they are of a dark brown color, and very fetid. As the disease advances, the stomach becomes affected, and sickness, nausea, and vomiting, occasionally prevail; the coun- tenance turns pale, and the skin becomes dry and rigid. If it continue for any length of time, universal emaciation, dropsy of the lower extremities, and relaxation of every part, ensue, together with a great loss of strength. Dissection in cases of diarrhea which have terminated fatally, have shown, that where it prevailed as a primary disease, ulceration of some portion of the intestines is the morbid change most usually met with; in which cases, the inner membrane is often abraded for a considerable extent, and its muscular coat laid bare. They have likewise shown, that the follicular glands are the most frequent seat of such ulcerations, and that they frequently become cancerous, and assume the same appearance as scirrhus and cancer in other parts. TREATMENT. In all cases of the above disease, the Cholera Morbus Lini- ment is an invaluable remedy. If the patient be severely at- tacked, let the Liniment first be used on the abdominal region, after which, spread a flannel cloth over the same, and use a CHOLERA morbus. 167 warm flat-iron gently over the belly: this course will impart warmth, and greatly facilitate the absorption of the Liniment; and just so soon as it is absorbed, temporary relief will be gained. In cases where discharges of blood occur, a tea made of smart weed, administered to the patient warm, will be of service. If the evacuations be hard and in little balls, a gen- tle cathartic may be given. If flatulency ensue, take freely of our Essence of Life. If the stomach be nauseated, apply very freely to the same our Stimulating Liniment; after which the Pectoral Tincture may be taken in nauseating doses, to cause vomiting. CHOLERA MORBUS. Cholera Morbus is a purging and vomiting of bile, at- tended with anxiety, painful gripings, spasms of the abdomi- nal muscles, and those of the calves of the legs. There are two species of this genus: 1. Cholera spontanea, which happens, in hot seasons, without any manifest cause. 2. Cholera accidentalis, which occurs after the use of food that digests slowly, and irritates. In warm climates it is met with at all seasons of the year, and its occurrence is very frequent; but in England, and other cold climates, it is most prevalent in the middle of summer, particularly in the month of Au- gust; and the violence of the disease has usually been greater in proportion to the intenseness of the heat. It usually comes on with soreness, pain, distention, and flatulency in the stomach and intestines, succeeded quickly by a severe and frequent vomiting, and purging of bilious matter, heat, thirst, a hurried respiration, and frequent, but weak and fluttering pulse. When the disease is not violent, these symp- toms, after continuing for a day or two, cease gradually, leav- ing the patient in a debilitated and exhausted state; but where the disease proceeds with much violence, great depression of strength ensues, with cold, clammy sweats, considerable anxiety, a hurried and short respiration, and hiccoughs, with 168 DISEASE AND ITS TREATMENT. a sinking and irregularity of the pulse, which quickly termi- nate in death, an event that not unfrequently happens within the space of twenty-four hours. The appearances generally observed on dissection, are a quantity of bilious matter in the primae viae; the ducts of the liver relaxed and distended. Several of the viscera have been found, in some cases, displaced, probably by the violent vo- miting. In the early period of the disease, when the strength is not much exhausted, the object is to lessen the irritation, and facilitate the discharge of the bile, by tepid demulcent liquids, frequently administered. It will likewise be useful to procure a determination to the surface, by fomentations of the abdomen, by the foot bath, or even the warm bath. When the urgent symptoms are relieved, the strength must be re- stored by gentle tonics, as the aromatic bitters, calumba, and the like, with a light nutritious diet: strong toast and water is the best drink. Exposure to cold must be carefully avoid- ed. The abdomen and the feet, particularly, must be kept warm, and great attention is necessary to regulate the bowels, and procure a regular discharge of bile, lest a relapse should happen. It will also be proper to examine the state of the abdomen, whether pressure gives pain at any part, because inflammation in the primae viae is very liable to supervene, often in an insidious manner. TREATMENT. Cholera Morbus has uniformly been successfully treated in the following manner, varying the treatment as the circum- stances of the case may require. 1st. Apply our preparations for fever, and cause a free per- spiration therewith. At the same time, apply the Cholera Morbus Liniment on the abdomen, and low on the back—re- peat until relief be gained. 2d. If the patient be troubled with flatulency, let there be repeated doses of the Essence of Life administered. 3d. Bathe the feet and legs in warm water, wipe dry, and apply the Liniment to them freely. COLIC. 169 4th. If relief be not directly obtained, immerse the patient in a saline bath. 5th. If the stomach remain irritable, let the Stimulating Liniment be applied to the pit of the stomach, and continue friction thereto for a considerable length of time, for just so soon as the Liniment is absorbed, the irritation of the stomach will subside. 6th. Should there be an appearance of inflammation of the bowels, a most powerful and continued application, for a long time must be applied thereto, with friction of the hand. 7th. Let the patient be supported by the use of tonics. The diet should be simple, and of easy digestion, and exposures to the influence of sudden cold should be avoided. The course above recommended, uniformly reduces the spasmodic affections, causes a free perspiration, determines the disease to the surface of the body, causes a reaction to take place, and in a very short time the patient is out of danger. COLIC. The appellation of colic is commonly given to all pains in the abdomen, almost indiscriminately; but, from the differ- ent causes and circumstances of this disorder, it is differently denominated. When the pain is accompanied with a vomit- ing of bile, or with obstinate costiveness, it is called a bilious colic; if flatulency cauy few hours, then at shorter intervals, and death takes place generally on the second or third day. A great number of applications have been recommended, but without success. TREATMENT. The treatment of the disease is of two sorts; the one con- sists in preventing its development; the other in checking its progress. The former consists in cauterizing the wound with iron heated to a white heat, the pain of the cautery being less as the temperature is greater. The cautery is preferable to the use of lotions, liniments, etc.; but it should be employed within twelve hours after the bite. It has been said, that in patients who were about to become rabid, several little pus- tules filled with a serous matter appeared under the tongue, the opening of which would prevent the disease; but this is not well established. Various remedies have been prescribed for the cure of a declared hydrophobia. Bleeding, even to syncope, appears to have produced the greatest effect, but without complete success. Preparations of opium adminis- tered internally or by injection, mercurial frictions, belladon- na, emetics, sudorifics, purgatives, etc., have been tried ineffect- ually. Yet the physician should not despair, as a remedy which has failed in one case may succeed in another. Above 36 282 DISEASE AND ITS TREATMENT. all, the patient should be treated gently, and his sufferings alleviated by consulting his comfort as much as possible, and the attendants should not forget that there is no instance of the rabies having been communicated from one man to an- other. SICK STOMACH, OR MILK SICKNESS. This disease is never known, only in the barrens and prairies, and in the flat lands, in the United States. In these regions it is sometimes very distressing, frequently proving fatal, un- less speedy relief be obtained. Among those who are best acquainted with the disease, there are as many conflicting opinions as to its cause, as there are of the spasmodic cholera. Some attribute it to the malaria, or miasmata of the low lands; others, to an impure atmosphere, while others attribute it to the use of milk from cows which have fed on a variety of poi- sonous vegetable substances, or from feeding on the meat of such animals. One thing is certain, that none in the infected region become obnoxious to the disease, who entirely abstain from a milk and meat and butter and cheese diet. The disease commences with trembling sensation upon the slightest exertion—loss of appetite—slight sickness of the sto- mach, and sometimes a burning sensation is felt in that region. The pulse at this time is natural; skin dry, or a clammy sweat occurs, if the nausea is great; thirst, great languor, and indigestion. Sometimes these symptoms continue a few hours; sometimes for several days. The symptoms above described are followed by severe vomiting, great prostration of strength, and total loss of appetite. The skin very little above the natural temperature; the extremities are generally cold; pulse at first slow and full; as the disease progresses, they become small and feeble; great thirst; dull and heavy appearance of the eyes, and obstinate constipation, are the most striking characteristics of the disease. Vomiting, in from ten to thir- ty minutes; the matter ejected from the stomach is at first mixed with bile; afterwards, a fluid nearly of the thickness SICK STOMACH. 283 of the white of an egg, and in many cases transparent. Vom- iting is preceded by a burning sickness at the stomach, which is temporarily relieved by vomiting; but in a few minutes the same sensations recur, and respiration becomes laborious; the patient continually shifting his position. The above are among the prominent characteristics of the disease which has baffled the skill of many physicians, but has been successfully- treated with our remedies. TREATMENT. This disease may be confounded with the cholera morbus, or the bilious remittent fever, though its peculiar features vary much from either. The great objects to be obtained in treat- ing this disease, are—first, to allay vomiting, procure a free evacuation of the bowels, and restore an equilibrium of the system. At the first stage of the disease, administer an emetic of the pectoral tincture, which will expel the irritating matter from the stomach. But if the patient be much exhausted, omit the emetic and give preparations of alkali and aromatics; at the same time, let an application of the Fever Liniment be made over the whole surface of the body, and place hot bricks to the feet and sides, which will cause a free perspiration; and in order to have a sudden and safe operation on the bowels, take one drop of Cioton oil once an hour. Take six drops of Croton oil, mix with one-eighth of an ounce of the same Lini- ment, and apply it to the abdomen; apply a warm flat-iron over the bowels, which will facilitate the operation. This may be repeated in three hours, if relief be not obtained from the first application, and so on, until full discharges occur. This mode is more safe and sure than to depend on internal remedies to move the bowels, as physic seldom if ever is made to operate in these cases in a less time than twenty-four hours. After the patient has obtained relief from disease, wash off with soap suds, and then apply the Liniment once or twice over the whole body, taking at the same time tonic bitters. 284 DISEASE AND ITS TREATMENT. INFLUENZA. The fact that this disease has of late years assumed more of the type of an epidemic than formerly, must be manifest to every attentive observer; and within the last year the mortal- ity in Europe and some parts of the United States has been nearly equal to that of the spasmodic cholera. To understand this disease, and to find a sure antidote, is of vast importance to the world. While the cholera raged most destructively among the poor, the influenza has raged among all classes of community. The rich have formed no exemption. The dis- tinctive features of the disorder appear to consist in the ex- tent to which the lungs have been implicated, the mucus membranes lining the air passages being in many cases in- flamed, and after a few days overloaded with viscid secre- tions, interfering with the arterialization of the blood. The oppression of breathing very urgent, attended with pain in the side. The pulse is generally soft, and when depletion is resorted to, delirium is apt to supervene. The cause of the seizure is generally attributed to the changes which so sud- denly occur in the atmosphere, from great dryness to great humidity, both states being accompanied with severe depres- sion of temperature. Notwithstanding much has been writ- ten on this interesting subject, such has been the conflicting opinions in regard to the real cause of the malady, and so changeful is its appearance in different countries and in differ- ent patients, that we shall labor more to point out a sure cure for the complaint, than to reconcile conflicting opinions of its proximate cause. TREATMENT. In no case would we recommend blood-letting. On the first attack, let the patient's feet be soaked in warm water; apply the Fever Liniment over the whole body, with plasters of the same to the bottoms of the feet, and a plaster on the FITS. 285 breast; hot bricks to the feet and sides; a full application of the Liniment to the neck and throat; wrap warm flannels about the neck; take Diaphoretic Drops sufficient to cause a free perspiration; take the Pectoral Tincture, in doses of from four to six drops, once an hour, or oftener, if the stomach be much overloaded by phlegm. These Drops may be taken in doses to cause vomiting, if, from the state of the patient, a vomit appears to be indicated. Repeat this sweating process once in six hours, until entire relief is given. The patient may drink freely of a mucilao-e of flaxseed or slippery-elm bark, taking the precaution to keep the bowels gently open. This treatment will generally relieve the patient within one or two days. It is sometimes necessary to depend almost entirely on the external applica- tion, and sometimes it may be advantageous to immerse the patient in a warm vapor bath. FITS. There are four kinds of fits, namely: apoplectic, epileptic, hysteric, and fainting fits. APOPLECTIC. The symptoms of this disease, are sudden falling to the ground, with deprivation of sense and motion, attended with deep sleep, and noisy breathing; the circulation remaining unimpaired. The causes are an excessive fullness of vessels, or a redun- dancy of blood, fullness of habit or body, hard drinking, too large doses of opium, blows, tight neckcloth, or whatever in- terrupts the return of the blood to the head. TREATMENT. Let the feet be immersed in very warm water; at the same time apply the Stimulating Liniment freely to the top of the 286 DISEASE AND ITS TREATMENT. head, on the neck and breast, and then to the whole body; and if it be caused by opium or strong drink, give ten or twenty drops of the Pectoral Tincture, or enough to cause vomiting; if from any other cause, give the Diaphorectic Drops, and place warm bricks to the feet, to produce speedy and profuse perspiration. This course, with friction of the hand, or a flesh brush, will generally give very ready relief. In some instances of this disease, the saline bath may be resorted to with advantage. EPILEPTIC. The patient falls suddenly, with a deprivation of sense, while the muscles of the face, and every part of the body, are violently convulsed. The causes are excessive drinking, sudden stoppage of the menses, severe fright, injuries to the head, teething in child- ren, and irritation of the stomach and intestines. TREATMENT. The treatment may be similar to that of apoplectic fits, with but little variation. The Fever Liniment, in this dis- ease, is preferable to the Stimulating, and the Pectoral Tinc- ture ought to be given in larger doses, and force down as much warm water as possible, until vomiting takes place free- ly. We have known the lock jaw relieved by the same means, only apply a double portion of the Liniment about the neck and jaws. HYSTERICS. This complaint appears under such various shapes, imitates so many other diseases, and is attended with such a variety of symptoms which denote the functions considered to be dis- ordered, that it is difficult to give a definition of it, and it is only by taking an assemblage of all its appearances, that we can convey any idea to others. This disease attacks in pa- FITS. 287 roxysms or fits. These are sometimes preceded by dejection of spirits, anxiety of mind, effusion of tears, difficulty of breathing, sickness at the stomach, and palpitation of the heart; but frequently it happens, that a pain is felt in the left side, with a sense of distension advancing upwards, until it arrives at the stomach, and then to the throat, with suffocating, faint- ing, stupor, insensibility; at the same time, limbs agitated, fits of laughter, crying, screaming, temporary delirium, and frothy saliva is discharged from the mouth. When the pa- tient recovers the exercise of sense and motion, there are no traces in the memory of what has transpired. There is se- vere pain in the head, and soreness over the whole body. In severe cases, there are no convulsions; the patient remains, to appearance, in a sound sleep, without any sense of motion. Hickup is sometimes the only apparent symptom. Unmar- ried women are the most subject to the disease, and often at- tacked about the commencement of menstruation. These fits are readily brought on by surprise, sudden joy, grief, fear, and by sympathy; by a sedentary life, and by sup- pression or obstruction of menstrual flux, or by excessive evacuations. In fact, all these various symptoms are often caused by obstructions, weakness, and nervous affections. TREATMENT. In all cases of hysteric fits, our Nerve Liniment is invalua- ble, both as an antidote and a remedy. It may be at first ap- plied to the most diseased organs, and afterwards over the whole body. Take of the Pectoral Tincture, as circumstan- ces may require. When the stomach and throat are affected, fifteen or twenty of these drops will give relief. We have never witnessed a case where these remedies have been inef- fectual. The disease is a distressing one, and merits more of the commiseration of physicians and friends, than is generally awarded. It is very important that the patient be treated with great delicacy and much kindness. 288 DISEASE AND ITS TREATMENT. It is not uncommon for flatulency or cholic to be an attend- ant on hysterics. When this is the case, our Essence of Life, taken in tea-spoonful doses, will afford immediate relief. Note.—In cases of spasmodic fits, which are produced by intemperance, or from almost any other cause, the first object to be effected, is to evacuate the stomach by a vomit. This can be effected by a strong solution of salt and water; after which, administer two drops of our Nerve Sanative, in warm water, once in fifteen minutes, and at the same time, make a free aplication of the same medicine to the throat and sto- mach, over which keep hot clothes, wet with camphor. As soon as the spasms subside, give a tea-spoonful of Essence of Life, in warm water, once or twice, which will relieve the great pressure at the breast. After which, apply a plaster of the Stimulating Liniment to the breast. PART II. TESTIMONIAL. OUR CONCENTRATED MEDICAL COMPOUNDS. The unparalleled success which has attended our medical pre- parations, from their first introduction in their crude state to the present time, imposes upon us the duty of making use of exertions to render them more extensively a blessing to the human family. We shall give the testimonials of a large number of witnesses to the efficacy of our remedies rather than our own recommendations. The facts which have been elicited, through the medium of a vast number of experiments, warrant us in embodying them with other interesting matter, in the form of a volume. The cases which we publish embrace almost every form of dis- ease, and it will be seen, by reference thereto, that the cures have been effected principally by our external remedies. In examining the following testimonials, the reader will find that the practice is simple and easy to be understood ; he will also find that large and nauseous doses of medicine can be dispensed with. The manuscripts from which the following extracts are taken are in our possession, with the entire signature of each individual thereto affixed. 37 290 TESTIMONIAL. TESTIMONIALS. Scald Head.—The following is signed by the father of the patient, and relates to one of the most extraordinary cases of cure, of that disease, to be found in the annals of medicine. A daughter of mine, N. M., aged 17 years, was. two and a half Years ago, afflicted with scald head. At first, little sores appeared all over her head, and her hair came off. In the month of June last, an application of Jewett's Cerate was made and continued with favorable effect; and, in two months from the commence- ment of these applications, a complete cure was effected. During the whole time of using the medicine, her general health remained good and unimpaired. It should be noted that the whole surface' of the head was affected to the thickness of a man's hand, and spread over with numerous boils, attended with redness and great heat. J. M. Piles.—I had been afflicted with the piles for twenty years: during the first ten years, periodically ; but, for the next ten years,. the attacks were irregular, until, finally, I was scarcely at any time free from pain, and, a great portion of the time, suffered ex- tremely. I applied, three years since, Pile Salve prepared by Col. Jewett, as directed, and, in twenty-four hours, was wholly relieved from all pain and inconvenience of every kind. Three years have now passed away without a single return of the dis- ease. J. B. Sciatic Affection.—Four years ago, I was attacked suddenly with sciatic affection, and a weakness and pain in the back, which continued, at intervals, two years, when the weakness and pain in the back became continual, and so remained until I applied a plas- ter of Jewett"1 s Stimulating Liniment. In about one week, I ex- perienced relief, and, by continuing the plaster four weeks, it has effected a cure. The last two years I was so weak in my back, and otherwise, that I could not lift ten pound weight. I had, SICK HEAD-ACHE, ETC. <&>)*■ during this period, been attended by four eminent physicians, without the least relief. N. S. Severe Pains, attended with Fevers, Delirium, Cough, &c.—About the middle of 11th month, 1834, I was taken with a severe pain in my head and right breast, attended with much soreness, difficulty of breathing, cough, some expectoration, numbness in my lower extremities, and high fever. My head was so much affected that I became entirely deranged. In this situation, my family were much alarmed, and, thinking that I was dying, sent for a physician, who ordered me, as I was afterwards informed, some mild diaphoretic tea, and, despairing of my life, directed, by way of experiment, an application of Jewett's Stimu- lating Liniment. This article was faithfully applied to my head, breast, stomach, and lower extremities, and, in a short time, I was very much relieved and restored to reason; perspiration took place, my pains ceased, and I was very soon restored to perfect health. I have no doubt this Liniment was the means of prolong- ing my life. M. T. Sick Head-ache.—At an early period of promulgating our re- medies, a severe case of sick head-ache of a female came under our treatment. This was the first case that we had seen which fully developed the powers of our medicines for the removal of that complaint. Though the patient had suffered long, the relief she gained was almost instantaneous. She soon became conva- lescent, and, shortly after, perfectly cured of the complaint. We notice this case as being the more extraordinary as, at the same time, the patient was laboring under uterine affections of long standing. The mode of application was such as we recommend in our directions, and which has continued to be so successful to the present time. Sick Head-ache.—-I have been afflicted with sick head-ache, occasionally, for eight years, and, for the last two years, I was at no time clear of it, until about the 25th of August last, when I ap- 292 TESTIMONIAL. plied Jewett's Stimulating Liniment to the top of my head, back of the neck, behind the ears, on the forehead and breast, and, in just four minutes from the lime of application, my head ceased to ache. It did not return on me for six weeks, and then only a slight attack, and I have never had it since. Previous to the ap- plication, I had been attended by most of the physicians of Co- lumbus without the least relief. URIAH STOTTS. City of Columbus, Mayor's Office, Jan. 6, 1835. Then the above named Uriah Stotts personally appeared, and made solemn oath that the statement above made by him is true, before me. JOHN BROOKS, Mayor. gO1" It is now three years since Mr. Stott has been troubled with the head-ache, more than others who do not complain of it, as a disease; but two years after he was cured, as he states, he was afflicted with a sore which had gathered in his head, and was discharged through the ear. A few applications of the Liniment to the head, and inside the ears, performed a thorough cure of the disease, and it has not returned upon him since. Dyspepsia, with Despondency of Mixd.—More than one year and a half ago, I was attacked with dyspepsia—stomach and bowels much disordered—digestive powers impaired—dry skin— and despondency of mind. I had no hope of obtaining relief, \ until six months ago, I applied Jewett's Liniment to the surface of my body. In two or three days my skin became moist, a re- laxation took place in my system, and I directly became relieved. Soon after the application, I threw off, from my stomach, large quantities of the most offensive matter, which afforded me much relief. With this application alone, I have been cured of the dis- ease, and have remained in health ever since. J. W. Rheumatism.—About the 20th of November, 1834, I was taken WHITE SWELLING, ETC. 293 with the rheumatism in one of my knees, which, in the course of one week, became much swollen and very painful, so much so that I could not walk without a couple of canes. I came to Co- lumbus on the 29th of November, and, on the third day after, ap- plied Jewett's Liniment to my knee and leg down to my foot; in eight or ten days, I became entirely free from all pain, and still continue free from all appearance of the complaint. W. H. M. Bilious Fever.—Lwas attacked'with severe pain in the head, back, bones, and legs, with hot fever and quick, hard pulse. I applied Jewett's Liniment on the whole surface of the body, and, immediately, all pain ceased. No other medicine was made use of, and, in about one day, I was restored to health. J. C. S. Case of White Swelling.—The following case of white swelling exhibits, perhaps, one of the most extraordinary cures ever performed by any medicine or mode of practice whatever. The history of it was given by the parents, and corroborated by the patient himself, an intelligent lad aged about 14 years. The indescribable pain and anguish which the sufferer had endured for months, without a single moment of alleviation, and the extreme anxiety and unwearied attention of the parents, afford a theme which the imagination can scarcely reach, much less the pen describe. But suffice it now to say the lad is restored, the parents are relieved from their deepest cares and painful anxieties, of which the reader can form a better estimate after reading what follows: Timothy Cochrane, jr., born in Ireland, September, 1820, was attacked in the year 1831 with a fever, by which he was reduced very low, and continued in a painful debilitated condition until the spring of 1832, when a white swelling made its appearance on his right hip, or upper part of his right thigh. The pain which he suffered from this swelling was of the most intolerable and excru- ciating character. It is impossible for any but those who saw 294 TESTIMONIAL. him to form any conception of his suffering; and he, himself, looks back with horror upon the dreadful scene through which he has passed. During the course of this painful malady, his at- tendants were obliged to resort to every means which humanity could suggest in order to afford the slightest mitigation of his suf- fering; and so extremely sensitive did he become, that he could not bear the weight of the lightest blanket; but was obliged to have some person constantly to hold the bedding loosely over him. In short, death would have been Avelcomed by him a thou- sand times as "a friend, the kindest and the best." In the summer succeeding the attack of the swelling, his parents left Ireland for the United States. The agonizing pains of the awful malady accompanied him across the Atlantic, and deserted him not when he landed in the city of Montreal. The best phy- sicians in Ireland had attended him in vain; and, on his arrival in Canada, three surgeons of the British army at Montreal and Little York were speedily consulted with no better success. From Montreal the family moved to Buffalo, where the advice of two eminent physicians from the city of New York was procured, who, as well as all others consulted, pronounced it a most despe- rate, if not an utterly incurable case. In the fall of 1832, the family settled in this city, when he re- ceived the attention of all the principal physicians in the place, and was abandoned by them all as incurable. Some time during the winter of 1832-'3, it was deemed proper to open the swelling, which was accordingly done, the pain still continuing as severe as ever. In the spring of 1833, however, the pain in the hip abated ; but he still continued extremely ill, very feeble, and without an appe- tite for food. In July, of the same year, he took the ordinary chill and fever of this climate, and, soon after, was attacked with dropsical swellings of the feet and legs, gradually extending to the abdomen and then to the head. The swelling, eventually, be- came very large, the bowels were enormously distended, the head nearly double the natural size, and the neck measuring about as large, in circumference as the head. His bowels, as is usual in such cases, were extremely irregular, either obstinately costive, or very much relaxed : his right leghad become very crooked and stiff: seven ulcers were located about the hip and groin, and all WHITE SWELLING. 295 the attendant symptoms indicated certain and speedy dissolution. It was in this most deplorable condition that his situation be- came accidentally known to Col. Jewett, when he immediately recommended the application of his Stimulating Liniment. In- ternal remedies were used at the same time, and, among others, one emetic. The other medicines were such tonics and purifiers of the blood as accompany Col. Jewett's remedies. The Liniment was applied to nearly the whole surface of the body, particularly the bowels, hip, and diseased leg, at the rate of four ounces per week. This course soon reduced the dropsical swellings, regu- lated the bowels, disposed the ulcers to heal, restored the appe- tite and general health, and made the patient comparatively com- fortable and happy. Jewett's remedies were first applied about the 1st of July last, and now (six months since) all the symptoms of disease are removed, the ulcers all healed up, and the hip ap- pears sound and well. The leg is becoming more and more straight and useful to him, with the prospect that he will eventu- ally be able to do entirely without his staff and crutch, and enjoy good sound health. The following certificate is from the parents of the patient: We certify that the above and foregoing statement, relative to our son, is strictly true, though falling far short of the dreadful reality of the case. T. C. B. C. \CTB It is now more than two years since Timothy Cochrane, jr., was cured of the white swelling as above stated, and he now resides in this city—has enjoyed perfect health, walks without a crutch, and, though one leg is much shorter than the other, he experiences but little inconvenience from it. He has been exami- ned by a large number of travelers who have passed through this city, and witnessed the unparalleled success of our medicines in this interesting case. We deem it worthy, also, of remark, that this was the first case in which a jacket, made of buckskin, (glazed cloth is better,) well covered with the Liniment, was worn constantly day and night. The benefits derived from it are evident; in fact, we have never known a single failure of complete success where that mode of application has been resorted to. 296 TESTIMONIAL. Dyspepsia, Pain, and Cough.—Dear Sir: For your encou- ragement, and for the information of the afflicted, I would inform you of the benefits I have received by the use of your Liniment. Having been afflicted with dyspepsia, loss of appetite, a severe cough, and pain in the breast, for a number of months ; and, un- able to obtain any relief, I was induced to try your Liniment. I have used about one bottle, and the effect has been to restore my appetite, my cough has ceased, the pain in my breast removed, and I find myself restored to perfect health. J. C. Cholera.—The most remarkable effect produced by the Lini- ment has occurred near Etna, in Licking county, where the cholera was raging, and had been unusually fatal in that village and its vi- cinity, Avhen a lad of fourteen years of age was violently attacked with the premonitory symptoms of that scourge of nations. I applied your Stimulating Liniment over the whole body with much fric- tion. The effect was truly astonishing; in a short time, every dangerous symptom was removed, and the next day the boy was apparently well. This relief was particularly fortunate, as no medical assistance could be obtained. J. C. Burns and Scalds.—I have used your vegetable Cerate in my family in cases wherein two of my children suffered severely; the one burned with fire on the hand, and the other was scalded with boiling water upon the hand. Immediate application of your Cerate was made in both cases, which prevented blistering, and soon effected complete cures. My wife has applied the Cerate to her nipples, when sore, which effected a cure in the course of one night. S. M. Bruise.—I had a finger smashed between two sticks of timber that were twelve inches square ; when the timber was removed, my finger was completely flattened. It was immediately pressed into its proper shape, and bound up with an application of Jewett's Vegetable Cerate. In less than fifteen minutes after it was bound DROPSY, DYSPEPSIA, ETC. 297 up, all pain ceased; and, in three days, my hand was sound and well, with the exception of the end of my finger and under the nail, which was tender. S. S. Remitting Bilious Fever, Delirium, etc.—A lady, under my care, laboring under remitting bilious fever for more than a week, accompanied with a profuse diarrhea, and delirious, was treated by an application of Jewett's Liniment. In twelve hours, reason was restored ; and the next day she was convalescent, and able to at- tend to the business of the family. T. H. Extract of a letter from Dr. S. R., of Hardiman county, Ten- nessee, July 5, 1835. Canker Sores, Risings on the Breasts of Females, etc. —" Col. Jewett: I have tried the efficacy of your Stimulating Lini- ment, and am truly gratified with the success I have had in its ap- plication for pains of all kinds, canker sores, risings on the breasts of females, cramp cholic, and external bruises. In fact, I am so convinced of its superiority over any other medicine, that I feel the want of it very much in my practice." Extract of a letter from Dr. A. McGowan. Putrid and Typhus Fever.—" Your Liniments I have now tested in two cases of putrid and typhus fever of very alarming type. One of the patients is now going about; the other, I feel satisfied, will be equally well in a short time. These diseases have proved fatal, in many cases, under the usual practice of de- pletion and minerals in this vicinity. I have likewise tried the Liniment in various cases of sick head-ache with decided effect." Extract from a letter of Dr. J. W„ of Harrison township, Licking county, Ohio. Dropsy, Dyspepsia, etc.—" I have been troubled, for ten years, 38 298 TESTIMONIAL. with a dropsical affection; warm weather increased it, with a suppression of urine. I made a full and thorough application ol your Stimulating Liniment to my bowels, and, strange to tell, I was, in a short time, relieved. I consider myself now cured of the complaint. In my practice, I found the most decidedly favor- able effect in cases of dyspepsia, and pains generally, by the use of your Liniment." Dyspepsia.—Col. Jewett: Sir, the bottle of Liniment which you presented me has been productive of much good, and relieved an amount of suffering far beyond my most sanguine expectations, from so small a quantity. I will relate a few of the surprising effects from the use of very small portions of it: W. S. had been afflicted with a severe pain in the stomach for several weeks, and which had rendered him unable to labor. He applied a small quantity of the Liniment to his stomach, and, in a short time, the pain ceased. I saw him some time after, and learned that his health was better than it had been for a long time. Two severe cases of dyspepsia have been relieved and cured by it in a short time. J. S. Head-ache and Foul Stomach.—About two weeks ago, I was afflicted with the sick head-ache and foul stomach. I applied to my head and stomach Jewett's Head-ache Liniment; and, in about four minutes, my head ceased to ache, and, without any other remedy, my stomach is restored to a healthy state, with a good appetite for any kind of food. E. II. Darting Pains in the Ear and Head.—I was attacked, six weeks since, with a peculiar and very severe darting pain from the ear through the forehead, caused by exposure to the cold, together with violent head-ache, which was removed, in the course of ten minutes, by the application of Jewett's Liniment. J. B. jCT" We shall omit the further publication of testimonials of INFLAMMATORY RHEUMATISM, ETC. 299 the cure of sick head-ache, except in cases where it forms a part of the evils suffered by patients laboring under other and more serious complaints; for, although sick head-ache is painful, and, in many cases, excruciating, we now consider it under the com- plete control of medicine. We have never known a failure when our Head-ache Liniment, together with its accompanying remedies, has been faithfully and perseveringly applied. Affection of the Liver and Spleen.—Last winter, I was attacked with a pain in my left side, which moved round into my back, and troubled me very much during the spring and summer. The pain, at length, got into both sides, and before and during a storm, or damp weather, it was severe beyond description. A slight swelling of the side occurred where the pain was principally seated, so that, by pressing the finger upon the place, there ap- peared a crackling similar to pressing a broken egg-shell (I do not know how to describe it better) under the fingers. I made a thorough application of your Stimulating Liniment to my side and back, which afforded me immediate relief; and, in a short time, by continuing the use of the Liniment, I was completely cured, and remained so ever since. C. G. H. Nervous Affections, Pains in the Back, etc.—In 1824, I was attacked with yellow fever, on the Island of Cuba, which ar- rived at a crisis in five days; but I did not recover my health. Since that period, I have suffered, continually, much pain in my sides, back, and shoulder-blades. The pains, at times, were vio- lent, accompanied with general nervous irritation. I continued in that condition until January, 1835, when I applied Jewett's Stimu- lating Liniment, which gave me some relief the first day. I con- tinued the application for ten days, when all pain ceased, and my general health was restored. P. A. J. Inflammatory Rheumatism.—Three and a half years ago, I was severely attacked with the inflammatory rheumatism, with 300 TESTIMONIAL. which I was confined nearly four months ; and, after my recovery, I was occasionally troubled with a pain in my side, and the rheu- matism has returned upon me every Avinter since my first attack. About three months ago, I commenced applying Jewett's Lini- ment, which relieved me from pain. I have used four bottles of the Liniment, and, at this time, I am entirely relieved of the com- plaint. For some time, I have had a glandular swelling on one of my arms, on which I applied the Liniment five times, which has nearly removed the swelling. T. L. Chills and Fever.—Some days ago, one of my children was severely attacked with chills and fever: I applied Jewett's Lini- ment over the whole surface of the body, which relieved the pain and averted the fever, and no return of chill or fever has since oc- curred. The next day, the child was as playful as usual. G. B. S. Cough.—I have been afflicted, for twenty years, with a very severe cough, and, for a long time, with many other bodily infir- mities of the most distressing kind. I have repeatedly sought aid from various sources, but received only partial relief, until I made use of your remedies, which was on the 26th of January, 1835. The first bottle relieved me from pains which I had suffered for six years, and they have not since returned. The second day I used it, caused me to throw off of my stomach much offensive, corrupted matter, and a great weakness in my back and breast en- sued. I applied a plaster of the Liniment to those parts, which soon removed the weakness, and I have not suffered any from it since. I have suffered much from dyspepsia for three years past; the most of the food I ate was either thrown up, or remained on my stomach to distress me; but now I have a good appetite for any kind of food, and eat all kinds freely without any injurious consequences. I have, generally, been obliged to set up for hours every night, in bed, to cough ; but now I sleep comfortably all night. I am now over sixty years of age—enjoy myself as well as I could wish—and find it my duty to continue the means that RHEUMATISM, etc. 301 a gracious Providence has placed in my hands for relief from pain and suffering. M. K. Dyspepsia and Head-ache.—I have been afflicted, for more than three years, with a severe pain in my head, said to be the nervous head-ache, which confined me much of the time in bed. I applied Jewett's Liniment to my head, which removed the pain in fifteen or twenty minutes, and I have not felt it since. I also suffered much from dyspepsia, and other distressing complaints ; but the use of the Liniments has also removed these difficulties. It is now about six months since I first made use of the Liniment, and I enjoy better health than I have for many years. I have a good appetite, my food agrees with me, and I am gaining in health and strength daily. L. A. H. Rheumatism.—It is now about four years since I had an attack of rheumatic pains ; my limbs and nerves were much affected; I was sometimes much worse than at others ; but, during the whole period, I was never free from pain. During the second year of my affliction, I was swelled ;n my ankles, knees, hips, and on my head, and my neck was stiff, so that, often, I could not turn to look at any object without turning my body also. The sinews of my limbs were swollen, and felt corded and tight like drum cords ; my nerves were affected, and I experienced death-like feelings, and I endured sleepless nights. Two weeks ago, I commenced ,the application of Jewett's remedies, for fever and ague, according to directions, and I have come to my natural feeling; I breathe freely ; the pain in my side is gone ; I am entirely relieved ; have the natural and easy use of my limbs ; and, during the whole four years, I did not, at any moment, experience any thing like the ease I now enjoy. In addition to rubbing the whole surface of the body with the Liniment, a plaster of the same was applied to my side, which soon produced a running sore; and, as the dis- charges from it took place, my side was entirely relieved from pain. J. G. 302 TESTIMONIAL. Sprain.—On the 8th of January, 1835, T strained my knee- joint—raising the knee-pan from its place—and it was believed that the knee-joint was cracked. Extreme pain and great swelling ensued. I applied Jewett's Stimulating Liniment, and heated it in with a warm iron, swaithing'it with flannel, and, in twelve hours, the pain entirely ceased. In ten days, a perfect cure was effected without the application of any other medicine. E. B. Fever and Diarrhea.—I was called on, last winter, to attend a child which had a high fever and diarrhea. I applied Jewett's Liniment over the whole body. In two hours, the child was wholly relieved from the fever, and had not another irregular mo- tion of the bowels ; no other medicine was made use of. J. R. Fever and Ague, and Cholera Morbus.'—I was attacked se- verely with chills and fever, to which I had, for a long time, been subject. I made use of the Liniment for fever, and, in three days, was perfectly cured of the complaint; and it has not returned upon me since, after a lapse of one year. I also used your Liniment for cholera morbus, which, in a very short time, cured me of that complaint; the attack was a severe one, and no other medicine was made use of. E. B. Extract of a letter from a Physician of high standing. High Fever and Extreme Debility promptly cured.—"1 have found, so far as I have tried your medicine, that it proves highly satisfactory. In one case, I was called to a boy who was brought home with a very high fever: preparations had been made to give it a course of the Thompsonian system ; but I im- mediately applied your Fever Liniment over the whole body, and, before the water got warm, the boy was in a full perspiration, and the fever left him immediately. In another case, I was called to a lady, in the country, who had been confined about eight weeks. I found her almost without pulse—extremities cold—skin dry— FEVER AND AGUE, ETC. 303 extreme pain in the head and back—and much febrile affection in- dicated. I applied your Fever Liniment with much friction, which gave her immediate relief. Several other cases have been relieved in like manner." Salt Rheum.—My wife has been afflicted with salt rheum for thirty years : all means resorted to, during that period, proved in- effectual until, about nine months ago, she applied your Vegetable Cerate, which relieved her in two days, and she soon became per- fectly cured of the complaint. She has not been troubled with it since, with the exception of a single instance : about six months after the cure, she had a slight breaking out on the hand, which was removed with one application of the Cerate. E. B. C. Extract of a letter from Dr. D. J. Piles and Palpitation of the Heart.—" Thirteen years ago, M. L., a lady of Montgomery county, Ohio, was attacked with the piles, which have continued to afflict her ever since. She was also troubled with pain in her back, bowels, sides, and shoul- ders ; and during the whole time, as she averred, had been afflict- ed with palpitation of the heart. "Four months since, I applied your Stimulating Liniment, on plasters, to her back and bowels, rubbing the same on her breast and shoulders. I also gave her the Pile Salve, two applications of which, with five applications of the Stimulating Liniment, to- gether with the plasters worn as above stated, have completely cured her of all disease, and she remains well at the present time. The same lady informs me that her daughter was violently at- tacked with pleurisy, and that she rubbed her side, and over the body, with the Stimulating Liniment, and threw her into a perspi- ration, and relief was obtained immediately." Fever and Ague.—Two months ago, I was taken with the fever and ague. 1 had chills and fever every other day. Just 304 TESTIMONIAL. before I expected the chill, on the seventh day, I applied Jewett's Fever Liniment to the bottoms of my feet, and put a hot brick to them, which caused a profuse perspiration, and the chill and fever did not return on me. I have had no more ague since. This was the only medicine I used, and I used it but once. J. B. %CTB We would here remark, that though the foregoing case is truly remarkable, (and we have known many such produced by our remedies,) we have not been in the habit of depending for a cure, on so slight an application, but at once apply the Liniment over the whole surface of the body, which we have never known to fail of accomplishing the desired object—a perfect cure. Measles.—Two months ago, my wife was severely attacked with measles, with severe pain in the bones, until I made an ap- plication of Jewett's Stimulating Liniment. The first application afforded relief. On the second application the measles broke out over the whole body, and in three days after, she was entirely re- lieved, during which time she made frequent use of the Liniment on her body, and wore plasters on the bottoms of her feet. Du- ring this whole application, she had no cough, nor sore eyes; and since her recovery, she has been in better health than she has ex- perienced for a year past. J. C. S. Extract of a letter from an aged and experienced physician. Intermittent Fever.—"In the last eight weeks I have been relieved from three attacks of intermittent fever. The first at- tack was violent. The second was brought on by exposure in wet weather. The third, several weeks after the second, was also occasioned by a violent cold. "Each attack was accompanied by a violent fever, pains in the bones, wandering pains and chills through the whole system, and a very afflictive pain fixed in the back, and across the loins, at- tended with lassitude, weariness, restlessness, and anxiety. These attacks were preceded with several days premonitory indisposition. MEASLES AND SCARLET FEVER. 305 They were all removed, in each instance, by one application of your Liniment, applied over the whole surface of the body, and keeping up a profuse perspiration thereby produced, by warm bricks to the feet, and covered warm in bed. To secure against relapse, I applied the Liniment to my breast, on several succeed- ing days. The effects of the Liniment in producing a sudden and copious perspiration, the composure and quietude it brings over the nerves, and the sudden restoration of appetite which fol- lows, invariably, its application, are truly surprising. In every instance alluded to, I felt myself perfectly relieved of all disease, on the ensuing day, which, after all our experience and knowledge of facts daily occurring, and considering my advanced period of life, and the severity of the paroxysm, could not fail to excite the admiration and surprise of myself and family. We used the Lini- ment freely. "T. H." Measles and Scarlet Fever.—Six months ago, my child, then three years old, was attacked with measles and scarlet fever at the same time; throat much swelled, with choaking and rattling in it; burning fever; and, to appearance, much excited with pain. The cords of his neck and cheeks were much swollen, and were very hard. His mouth and throat were raw. I gave him a spoon- full of sweet oil, and then applied Jewett's Fever Liniment to his neck, and all over his body at night. The child was thrown into a perspiration, rested well through the night, and in the morning all the dangerous symptoms were removed. The child had a good appetite, and in a few days Avas perfectly cured, without the use of any other medicine. A. S. Extract of a letter from a physician, on cutaneous absorption. Facts are better than arguments.—"I have knoAvn the Liniment to produce profuse perspiration in a few minutes, re- lieve violent pain, and throAV off a fever in a few hours. In bil- ious fever I have used the Liniment much to the comfort of the patient, in removing sick stomach, head-ache, back-ache, etc., often 39 306 TESTIMONIAL. in ten or fifteen minutes. It is also most excellent in rheuma- tism, and is a sure cure for nervous head-ache, if persevered in. "I could produce certificates for the cure of the piles, by the use of the Pile Salve, in one case of thirteen years, and in anoth- er of twenty years standing. "The Cerate I knoAv from experience, to be excellent for the cure of burns, scalds, and sores of every description; also sprains, bruises, etc. " The Head-ache Liniment seldom fails to relieve in five or ten minutes, and if persevered in, never fails to perform a perfect cure. " I could at this time publish more than one hundred testimo- nials, proving the above facts. For cholic pains and boAvel com- plaints, in infants, the effect of the Cholera Morbus Liniment is truly astonishing, frequently producing instantaneous relief! And still Avill it be longer contended, against all of the above facts, that there is no cutaneous absorption ? " T. N." Chills and Fever.'—I had a severe attack of chills and fever, attended Avith pain in the head, breast, and loins, loss of appetite, etc. I had been in this way for some days, and found myself growing worse continually. I made use of Jewett's Fever Lini- ment, at evening, agreeably to directions given in such cases; it produced plentiful perspiration. Next morning I found the fever was gone. I discharged bile freely, by the bowels, and have not had any symptoms of the complaint since. I have not the smallest doubt that, in case I had not applied the Liniment, I should have had a long and lingering spell of sick- ness, as that has formerly been the case, in several preceding seasons in Avhich, notAvithstanding the faithful use of all other means, I have had a similar complaint continuing Avith me for months; but Avhich, in this case, I Avas relieved of in one night, without the aid of any other medicine. J. R. White Swelling and Piles.—Thy Liniments have perform- ed wonderfully. A white swelling on a boy's knee, which had been for three years standing, and pronounced beyond the reach PARALYSIS--AFFECTION OF THE SIDE, ETC. 307 of medicine by a physician, has been cured. One case of long standing of piles has been cared with the Pile Salve. There are several cases within my knowledge, which have been cured with the Stimulating Liniment, the particulars of which I will hereafter furnish thee. B. W. Extract of a letter from J. W. Esq. of New-York, dated Sep- tember 16, 1835. Cholera.—"A neighbor of mine was recently taken with the cholera. All the symptoms indicated a violent, sudden, and fatal termination of that disease. Your Liniment was fully and faith- fully applied, and in a feAV minutes he said he felt as if he were in aneAvworld; reaction took place, and he soon recovered. The man declared it as his opinion, that he could not have lived fifteen minutes, had it not been for the Liniment. Our physician told me your preparations were the cheapest medicine he ever met with. He says your Pile Salve never fails, when properly ap- plied." From the Rev. J. B., M. D., October 30, 1835. Recommendatory letter.—" Your medical preparations, so far as I have had an opportunity of trying them, have answered all the expectations raised by your Advertiser, and were it necessary I could furnish you some additional testimony of their adaptation to the cure of disease. In every instance where I have recom- mended their application, positive benefit has been derived, and the most entire satisfaction expressed by the patients using them. I have not knoAvn them used in a single case, Avhere they have not been sovereign and all-sufficient, in affecting Avhat they were de- signed to accomplish." From a letter of Dr. M. G. Paralysis—Affection of the side.—" My own health, for some time, has been in a feeble state, and from some unknown 308 TESTIMONIAL. cause, I suddenly became much Avorse. A cessation of a proper circulation appeared to take place on one side, leaving me in a most distressed situation, attended Avith much pain. 1 made a liberal application of your Liniment, and the effect far surpassed my expectations. I Avas immediately free from pain, and am rapidly on the recovery of health; my appetite, from being very poor, is fast returning to its proper state; and I have a desire that the community generally, may become acquainted Avith the saluta- ry effect of these invaluable remedies, in relieving the afflicted." From Dr. J. S. Fever and Sick Head-ache.—" From the trials made of your medicines, they are greatly approved of: in one case of fever, particularly, a patient given over, and thought by all to be past recovery, by a thorough application of your Liniment for fever, has been restored, and is now able to be up and about. The patient is the Avife of a respectable gentlemen who was violently opposed to your medicines, but now convinced of their power to heal. When tha box came to hand, he himself was laboring un- der a violent sick head-ache : he applied the Liniment to his head, and, in just four minutes by the clock, he was perfectly at ease. He continued its use for a short time, and is entirely cured of the complaint to which he had been subject." Extract of a letter from Dr. John Steele, of Frankfort, Missouri, October 16, 1835. Remarkable case and cure of a Child.—" I have used two bottles of your Liniment upon my infant child, who has never seen a well day in his life. He is now eleven months old, and was born with disease. When he was three weeks old, he weigh- ed three pounds when dressed: he now weighs seven pounds. From the time he was born until the present, he has been kept alive by botanic medicines, and chiefly by injections. Had I kept a regular account of all the applications and medicine given, it would astonish thousands ; it is now better, and has a prospect of REMARKABLE CASE. 309 recovery. Should he get well, I shall ascribe the praise, under God, to your Liniment. When he was about a month old, he broke out on his hips, thighs, and legs, like a burn or scald, and would blister as bad as if flies had been applied. It Avould con- tinue in this way for three or four weeks at a time, and then dry up for a few days, and then come out again in the same way, only spreading more each time, successively, until it got nearly all over him. At one time, he did not open his eyes for eleven days, and often, in that time, the blood would run down from his eyes, on his cheeks, to his neck. I have been thus particular, in order, should he live, you may see what has been done by your remedies, and that the world may be benefitted thereby. What I have said, is but a faint representation of his sufferings, but I have now strong hopes of his recovery from all disease." Extract from the same, dated February 23, 1836. " About the last of September, I received your Liniment, the child having grown much worse : in August, it was blind eleven days, and I then expected both eyes would run out. When the Liniment came to hand, I applied it to all parts of the body that were sound, and the Cerate to the sores. At first, relief was very perceptible, and then no further improvement appeared for per- haps six weeks ; and had you not written to me to persevere, I should have given it up as irretrievably lost. After the time men- tioned, Ave began to discover that the plaster applied to the stomach had an evidently good effect. The stomach was relieved from the tough phlegm which had been the cause of much of its suffer- ing. It gradually mended, the eruptions became less, and soon after entirely disappeared." Extract from the same, March 15, 1836. " I am happy in informing you that your remedies have proved a blessing to me in restoring my afflicted infant child to perfect soundness ; it is noAv free from all disease, and is full of life and activity. It has been entirely Well for two months, and is grow- 310 TESTIMONIAL. ing as fast as any child. I could give you many cases Avhere your medicines have been applied to the saving of life ; but it ap- pears useless. Any one still disposed to doubt, in this region, Avould not believe though one should rise from the dead and de- clare it." %CTB The experience in practice and application of our medicine presented in the above case, shoAvs, in a most striking manner, hoAV important it is to persevere until relief be obtained. The child to Avhom Ave refer, and Avhose case is represented in the let- ter of Dr. Steele, is noAV nearly four years old ; enjoys good health at this time; and, in fact, far better than that of any member of the family, Avith fair prospects of its continuance. Extract of a letter from Dr. T. N., M. D. " Your most excellent Liniments have aided and accelerated cures in many cases. The more I use your remedies, the more clearly is the doctrine of cutaneous absorption demonstrated to my mind. In fever cases, your remedies are, indeed, invaluable, in- variably removing all pain when properly and thoroughly applied, and producing a full and free perspiration. I can, with the utmost confidence, recommend them to the whole family of man." Extract of a letter from Dr. J. V. D. G. Bilious Fever.—" I have seen much good consequent to the use of your medicine, but Avill trouble you with the relation of two remarkable cases. Maj. D. P. C. Avas taken very suddenly Avith vomiting, pain in the head, back, and extremities, with high fever, which progressed rapidly, and, in the course of ten hours, he be- came entirely delirious—a wild look of the eyes—face very much flushed—and required three persons to keep him in bed. Every person had despaired of him, and was conscious he would die. He had been puked freely, and every other known means made use of, to no effect. I, however, resolved to make a bold effort to save him, and proposed trying your Liniment, Avhich was agreed WEAKNESS AND TREMOR, ETC. 311 to. I commenced by shaving the head, and then rubbed it on well; applied it all over the stomach and bowels; applied warm rocks to his feet, back, etc. In the course of three hours, he came to his proper senses, i In three days he was walking about in his room, and in a few more was off visiting his friends. The other case, in which your life-saver, (I call it) has had equal effects as in the above, was that of a lady, who had been sa- livated so much, that the jaw had sloughed partly off. Parts of her flesh had mortified, where repeated blisters had been applied. I thought it a bad chance to save her, as part of the jaw-bone was bare. I, however, commenced the application of the Liniment, and, to my utter astonishment, in a week the parts commenced healing, and in three weeks she was entirely well. The Liniment checked the mortification as soon as applied, and has been the means of saving her life." Remark.—It was a long time after we were aware of the fact, that our Liniments would instantly arrest fevers of every type, that we ventured to say any thing on the subject, being satisfied it would require more faith to believe the astonishing fact, than any man's assertion Avould create. The fact is now well established by hundreds of cases, which have been cured in less time, and with less expense, and much more "'certainty, than the world ever witnessed, by any practice heretofore known ;. and had the talent- ed writer of the foregoing letter understood, what by practice he will soon learn, Avhen he applied the Liniment to Major C, the major Avould probably have been well on the folloAving day. In all such extreme cases, Ave apply the Liniment over the whole surface of the body, once in two or three hours, and warm up the system as rapidly as possible, thereby producing a free and copi- ous perspiration, which is kept up with warm bricks to the feet and sides, if necessary. We also give our Diaphoretic Drops freely. Extract from a letter of S. M., Indiana. Weakness and Tremor.—"I have tried thy Liniments in sev- eral cases Avith very good success. I will give thee one case. A child of twelve years old was taken with a tremor, weakness, and 312 TESTIMONIAL. lameness in her knees and legs ; legs much sAvelled and appetite gone. I bathed her feet and legs in Avarin Avater, wiped dry, and applied the Liniment from the knees down; put stockings on, and hot bricks to her feet. First night some improvement; next night repeated Avith good effect; third night rubbed the breast, spine, sides, legs and feet as before, and drank Avarm teas as she got up in the morning. Apparently Avell, and still remains so, with a good appetite." Note.—If the patient in the above case had received a tho- rough application of the Liniment all over the body in the first instance, with hot bricks to the feet, and the exhibition, freely, of our Diaphoretic Drops, it would have saved her tAvo days sickness, and much pain and trouble. Extract from a letter of Dr. J. C. Fever, Sore Eyes, etc—" I have fully tested the virtues of your medicine to my entire satisfaction. Your Cerate is invalua- ble, and exceeds every other article of the kind of which I have any knowledge ; but I know not Avhich of your preparations is en- titled to a preference, when compared to others of your make. I will give you a case or two, among many proofs of their efficacy. " My Avife Avas attacked severely Avith fever. I applied your Li- niment, and in less than fifteen minutes she was relieved from all pain, and in a free perspiration. She was perfectly well in a few days. " A young lady scalded her foot badly. Blisters had arisen all over the top of the same. I applied the Cerate, and in five mi- nutes the pain was entirely gone. In a feAV days the scald Avas entirely healed and cured. " Some weeks since I suffered severely with sore eyes, occasion- ed by loss of sleep and exposure to cold. I applied eye-waters of various kinds, and all means within my knoAvledge, Avithout gain- ing any relief. I had many patients to attend to, day and night. I resorted to a trial of your Cerate. In a few minutes from the time of application of it, all burning pain left my eyes. I Avent to sleep a few hours, and when I awoke, found great relief. I continued to apply it a feAV days, and completed a perfect cure, has continued without a return of the disease. PAIN IN THE SIDE AND AGUE CAKE, ETC. 313 " I have since applied it in several cases of sore-eyes, with per- fect success in all." Extract of a letter from Dr. D. I. Cough of thirteen years standing cured.—" Mrs. G., on hearing the reports of the virtues of your preparations, called on me for some of the Cough Liniment. She had a severe cough of thirteen years standing, Avhich had defied all skill and medicine within her poAver to obtain. I supplied her Avith one bottle. She soon applied for another; and before the last bottle was entirely used, she informed me that her cough Avas entirely cured, and her health completely restored." Dislocated Joint.—One of my sons fell and put his shoul- der-joint out of place, and cracked the collar-bone. I set the arm into its proper place, and applied Jewett's Liniment, which reliev- ed him at once from pain. I continued the application for a week. His arm was SAVung up three days. In ten days his shoulder was perfectly well. J. R. Weakness in the Limbs, etc.—My son has been afflicted for five years with weakness in his limbs, and severe pain in his side, until sometime last spring, when he was entirely confined to his bed. He Avas troubled with the boAvel-complaint, and one of his thighs and arms had perished away very much. Two months ago he commenced using your Liniment, which cured him of the bowel-complaint directly, and relieved him of his pain. His joints and limbs, (which were drawn out,) are coming into place, and his thigh and arm gaining as to size. Pain in the side and Ague Cake.—A daughter of mine was afflicted Avith a pain in her side, and a cake which seemed to be formed under her ribs, attended with severe cough. The applica- tion of your Liniment relieved her of all those complaints in a very short time. A nail was run into the foot of a child, which affect- 40 314 TESTIMONIAL. ed it all over the whole system. The application of your Lini- ment wholly relieved the child from pain, and the foot got Avell immediately. C D. From Dr. J. C, January 1836. Nervous Affection.—" There has been a disease prevailing in this region, for some time past, Avhich has been very violent from its first appearance. It is attended with excruciating pain in the ear, jaAV, temple, neck, shoulder and side, and sometimes im- mediately folloAved by delirium and general debility. I have at- tended a number of cases, and have been so fortunate as not to lose a patient. One of my children Avas attacked Avith the disease two days ago. I applied your Cholera Preparation over the whole body ; at the same time gave an emetic and an injection ; in one hour she Avas entirely relieved, and fell into a sound sleep, at which time I was obliged to leave her, and did not return for twelve hours, Avhen I found her in a violent fever. I immediately applied the Liniment thoroughly, Avhich caused a free perspira- tion in a few minutes, Avhich Avas kept up for several hours, and she is now entirely Avell." From Rev. A. B. Injury of the Cartilage of the Heel.—" In July, 1835, Avhile walking the street, I stepped a little crooked on the pave- ment, Avhen I felt something give Avay, like the tearing of the tis- sue between the muscles of the left heel. For ten days after, I continued to Avalk on it as usual, feeling it tear a little more now and then ; but at the end of ten days my leg became very painful, and my whole system was so affected, that to the ends of my fin- gers and toes I Avas in acute pain, and my jaws began to stiffen at the joints. In this situation I sought relief from the highest sour- ces of skill, and applied various remedies as directed, but gained nothing more than partial relief. I was compelled to use crutches, and traveled in a light wagon. On the 20th of September I went to Columbus, Ohio, where a friend gave me an ounce of Jewett's Stimulating Liniment, which I applied according to directions, and SCARLET CR TYPHUS FEVER, ETC. 315 in one week I could go without crutches, and in two weeks could walk Avithout limping. The heel continued to strengthen from the use of it until the 10th of January following, when my supply of the Liniment was expended; at which time, and for several weeks previous, I felt free from all inconvenience from the wound." From Dr. T. N. Pleurisy, Head-Ache, Scalds and Small Pox.—"The effects of your Liniments are astonishing to all who try them. I have been completely successful with them in Pleurisy, Measles, Head- ache , Scalds, and applied them in one case of Small Pox, which they cured Avithout any other medicine, in a very short time." From Dr. W. H. F. Measles and Freezing.—" I will mention a few cases in which your remedies have been eminently successful: " Measles.—A boy afflicted Avith measles, oppression of the lungs, wheezing, or difficult respiration, whose obstinacy preclud- ed the possibility of administering medicine internally, was rubbed freely with Stimulating Liniment, over the limbs, breast and sides, upon which the Measles came to the surface. The result Avas, the boy got Avell in a very short time, Avithout having that danger- ous cough Avhich usually folloAvs that disease. " Freezing.—By exposure by riding in a very cold day,I had both feet frozen, so that upon a moderate application of the hand, in the act of rubbing to produce a circulation, a detachment of skin came off, as though hot embers had been applied to the part. " I immediately applied the Cerate, and so sudden and effectual was the cure, that after the following morning, no inconvenience was experienced, except a sense of tenderness to the touch." Scarlet or Typhus Fever.—" During the winter past, there has been a most obstinate fever prevailing in this region, called by some physicians, Nervous Typhus, and by others, Scarlet Fever. 316 TESTIMONIAL. Those Avho survived, (for but few recovered at all,) have lingert' from twelve to twenty Aveeks. One man continued, after getting about sixteen Aveeks, and then died. In fact, very feAV recovered entirely. Two young men, Avho had the same complaint as those Avho died, and Avere equally afflicted, were treated Avith Jewett's Fever Liniment, and were immediately relieved; and Avithin four days were out of danger, and since regained their health as sound as ever." C. R. From Dr. D. I. Sciatica.—" About four weeks ago I was attacked Avith a se- vere pain in my left thigh, seated a little below the hip joint, and extending someAvhat lower, to the knee. This Avas on Wednes- day. On Thursday the pain and sickness increased. In the even- ing, before going to bed, I applied Stimulating Liniment. Friday it Avas still Avorse, and in the evening the Liniment was applied as at first. On Saturday it was worse than ever. I have been thus particular, to shoAV how necessary it is, not only to persevere, but to begin in earnest, and make thorough and repeated applications at first, in such cases. On Saturday, I Avas determined to give the Liniment a fair and thorough trial. I used it three times during the day, with much friction, by a hot stove, and once again before going to bed. At the last time I had my back well rubbed. On Sunday the Liniment was used three times, from the hip to the knee. On Mondav it was entirely Avell, and remains so to this day." From J. D., M. D. Ring Bone on the Ankle.—" Your Liniment is in very high repute in my practice. In one case it has performed a cure, pro- nounced by medical gentlemen of skill and science, of all orders, to be beyond the reach of medicine. The patient had walked with crutches three years, being afflicted Avith what the most learned among physicians called a ring-bone upon his ankle. He applied COLD PLAGUE, ETC. 317 the Stimulating Liniment six Aveeks, and had no more use for his crutches. He was perfectly cured, and remains so to this day. Consumptions, liver omplaintx, and pains, in all instances, have been relieved by your remedies. An Interesting Case.—" I was called to prescribe for the daughter of a Mr. D., of Franklin county, Ohio. She was ten years old. When I first saw her, her joints were much swollen ; flattened ribs ; great incurvation of the spine, from the first supe- rior lumbar vertebra to the inferior cervical vertebra of the neck ; general emaciation ; diseased state of the lymphatics ; running in the immediate vicinity of the alimentary canal; consequently a derangement of the bowels; loAver extremities much swollen; pain over the region of the lungs, on the right side ; protuberance of the belly, attended Avith hardness and acute pain to the touch; all of Avhich rendered her entirely unable to rise from the bed. She was at the same time affected Avith a severe cough, attended by flashes of fever. In this distressed situation, I commenced the application of Jewett's Liniment over the Avhole surface of the body, at the same time applying plasters of the same over the more immediate regions of the pain. I also gave her internally Jewett's Vegetable Syrup, accompanied Avith Diaphoretic Drops. On the first night after the application, the patient Avas relieved from vio- lent pain; shortly after, her bowels became regulated; and by continuing this course about six Aveeks, the patient has been cured of all the above complaints, and is noAV, to all appearance, in per- fect health. I consider this case one of the most extraordinary I have ever met with in my practice. When I first saAV her, I had but little expectations of affording her any permanent relief. Wm. J. R., M. D. From Dr. B. R., M. D. Cold Plague.—"The first case in which I applied your Lini- ment was in a severe attack of cold plague. The patient had dry skin, much fever, strictures in the breast, pain in the head, bowels, and limbs. He soon became entirely deranged. I applied the 318 TESTIMONIAL. Liniment to the Avhole surface of his body: gave him freely of the Diaphoretic Drops; placed hot bricks to his feet and sides, which caused a profuse perspiration. He came to his right mind, the fever Avas reduced, and the next day he was able to set up. I made another application of the Liniment, Avhich entirely cured him, and on the third day he Avas enabled to attend to his ordi- nary business." Tumors and Erysipelas.—"A Mr. C. of Fayette county, had been troubled for a long time, Avith a breaking out on his legs. Very large lumbs appeared; much heat, and very much inflamed, and attended with severe pain, so that he Avas frequently unabled to attend to business. He had offered large sums of money to be cured, but could obtain no relief. By the use of the Lini- ment and Diaphoretic Drops, he was cured of the complaint in about one Aveek, and still remains free from disease." Cold Plague.—" Another case.—The Avife of M. C, Esq., Avas violently attacked with cold plague, in its most frightful form. The third day after she was taken, she Avas bled with bad effect; her friends considered her beyond the reach of medicine, and that opinion seemed to be grounded in part, by the evident loss of hope expressed by her physicians. For myself, I saw no hope from any medicine or mode of treatment of Avhich I had any knoAv- ledge, and made trial of your Liniment, as an experiment. I caused the Liniment to be applied over the Avhole surface of the body, and placed hot bricks to her feet; but such was the torpid state of her system, that these applications appeared to do no good. In a short time I repeated the same means, and the third time, placed a plaster of the Liniment on her breast, over which a bag of hot oats Avas applied, Avhich soon caused a copious per- spiration. Her fever Avas in a short time reduced, her pains left her, and within twenty minutes she fell into a gentle sleep. The next day she was free from pain, and enabled to sit up; and in about three days after, she Avas entirely restored to health." Dysentary and Dyspepsia.—Josiah Rush, of Madison county, Ohio, has been afflicted two years with the dyspepsia, very se- RHEUMATISM. 319 verely; so much so, that his physicians had despaired of his life; and for the last nine months he has had a continual dysentery. He assures me, that within the period of the affliction, he had voided more than six gallons of blood; was in continual pain; and most of the time was obliged to go to stool several times in an hour In this situation I was called to prescribe for him; and my first application Avas made of Jewett's Liniment, over the ab- domen and back, which relieved him of pain, and checked his bowel complaint. He continued this course for about three weeks* which entirely relieved him. His bowels have become regular, and he is at this time in good health. Wm. J. Radcliff, M. D. Columbus, June 8th, 1836. From Dr. L. G., M. D. Asthma.—"A negro Avoman of ours, that had been afflicted Avith the asthma for twenty years, has been entirely cured by the use of your Liniment and Pectoral Tincture. It is now seven months since she has had any symptoms of the disease." From Dr. B. R. Pain in the side, Cough, etc—"A Mrs. G., a neighbor of mine, had been afflicted for several months, with soreness of her limbs, pain in the side and breast, loss of appetite, cough, and restlessness at night. She grew so bad, that I was at last called, and applied your Liniments, and gave her of your Syrup, for three days, Avhen she was entirely relieved of all her complaints, and is now entirely restored to health." Rheumatism.—"Mr. G. then employed me to doctor his son, who had been for three years severely afflicted with the rheuma- tism in his shoulders, back, hips, knees, and ankles. His thighs and legs had perished, so that they had almost the appearance of a skeleton. I applied your remedies for the rheumatism fully in this case, and in a few days he was able to walk, and is now en- tirely Avell." 320 TESTIMONIAL. Inflammatory Fever.—A Mr. R., Avas attacked violently by an inflammatory fever. Dry skin; pain over the Avhole body; delirious, and was considered almost beyond the reach of medical aid. I thought this to be a good case for a still more thorough trial of the efficacy of your Liniment for Fevers, and Avas deter- mined to try it Avithout the aid of an emetic. I did so, by rubbing it over the Avhole surface of the body; gave him Diaphoretic Drops, Avhich allayed the pains, and produced a gentle perspira- tion in fifteen minutes. I ordered the Drops continued three hours. The next morning I found the fever gone, and the patient entirely relieved. Severe Case of Cholera Morbus and Fever.—About the last of June I Avas suddenly attacked, at midnight, with pains and sickness at the stomach, which continued until daylight, Avhen vo- miting, diarrhea, cramps in my limbs, high fever, and pains of the most excruciating severity over the whole region of the body, rendered me unable to rise from my bed; in fact, I expected no- thing but speedy dissolution. In this distressed situation, relief came through the agency of Col. JeAvett's Liniment for Fever; a friend applied it twice over my whole body, put hot bricks to my feet and sides, applied hot cloths to my stomach and bowels, and gave me stimulating powders. These preparations caused a pro- fuse perspiration, Avhich continued nearly two hours. As soon as the sAveat commenced, I became measurably relieved; soon after my pains ceased, and the fever Avas gone. About one o'clock I was washed all over with soap-suds ; the Liniment was again ap- plied, and clean clothes put on. My appetite began to return ; I slept well the succeeding night, and the next morning was able to attend to the avocations of my family. I had been unwell for two weeks before this attack. Columbus, Aug. 18, 1836. C, S. Remark.—We saAV Mrs. S. during her distressing illness, and, from our intimate acquaintance with the spasmodic cholera, we should have pronounced her case one of that character, had the epidemic been among us. In fact, of all the frightful cases of that disease, Aye have seldom seen one more distressing. HYDROCEPHALUS, ETC. 321 From Dr. B. E. Rheumatism.—"A Mr. II., of this county, had been afflicted by rheumatism five months, and was cured by a full application of your Rheumatic Liniment, in four days. We first cleansed the system, and then applied the Liniment. Another patient, who had been crippled nine years Avith the same complaint, has been cured in a very short time, by the application of your remedies for that disease." Wounds.—" One very bad wound, cut to the bone with an axe, was healed sound in four days, by the use of your Cerate." Nervous Head-ache.—" My father had been afflicted nine years with nervous head-ache, and no relief could be obtained by medicine. I made one thorough application of Liniment for Head- ache ; the pain was gone before I had done rubbing on the Lini- ment, and it did not return again for many months. This, how- ever, is only one case out of many Avhich have been cured by your Head-ache Liniment. I consider it a sovereign remedy for all kinds of head-ache." From Dr. A. McG. Hydrocephalus.—" I am happy of having it in my power, to state that a most alarming case of hydrocephalus has yielded to the persevering use of your Stimulating Liniment. In all my experience, I never witnessed so distressing an object who sur- vived. Every suture was open to a considerable extent; the head hideously enlarged; the scalp protruded much above the sutures; the eyes were violently distorted; pupils dilated; in fine, every symptom usually attendant on the last stages of that dreadful dis- ease, Avas evidently shoAvn. The Liniment was applied three times a day, with friction of the hand, and washed Avith soap suds every three or four days, Avearing a flannel cap. as steadily as cir- cumstances permitted. An application was also made, in like manner, to the stomach and bowels, say sometimes once, and sometimes twice a day." 41 322 testimonial. From Dr. A. E. General Debility.—" The first case I have to mention, was the Avife of J. M., Avho was, in January last, afflicted Avith gener- al debility, cramp in the stomach, and pains over the Avhole body. I gave her the Antispasmodic Tincture, which gave some relief. She was then attacked by sIoav fever, from which she Avas partial- ly relieved; but soon after there appeared an ague cake in the side; hoarseness, general emaciation, loss of appetite, and a sense of extreme burning and sickness at the stomach, Avhich I Avas un- able to remove, by any medicine in my possession. I Avas there- fore induced to resort to your Liniments, Avhich I applied faith- fully, and to my utter astonishment, she gained almost instanta- neous relief, and was, by a continued application for a few days, restored to perfect health, and so remains to this day." Croup.—" A child of T. R. Avas violently attacked by an in- flammatory fever. I was called in about tAventy-four hours after the attack, and applied your Fever Liniment to the throat, back, breast, boAvels, hands, and feet, Avhich caused a free perspiration, and in less than two hours relief Avas obtained; and after a second application, the child Avas perfectly restored to health. I could wish that thousands of mothers could know these facts, as it re- quired but half an ounce of Liniment to effect a cure, and no in- ternal medicine Avas administered." Fits occasioned by Croup.—" A child under my care, who had had four severe fits, probably occasioned by the croup, was almost instantaneously relieved by one application of your Lini- ment. I found a second application unnecessary." Quinsy.—" A man by the name of P., Avas so afflicted, that he Avas unable to open his mouth. I applied the Liniment three times, which entirely cured him." Mental Derangement.—" I was called to visit a man in Knox county, Avho had for some time been laboring under mental derangement. He had been attended by gentlemen of skill and eminence, and given over by them as incurable. When I first saw him, his boAvels were considerably protruded; legs, feet, and RHEUMATISM, etc. 323 arms cold; and was generally debilitated. I applied your Fever Liniment to his legs and arms, and the Nerve Liniment to his head, neck, and on the whole length of the spine. He directly became partially relieved. The same application Avas made a number of times, and in a week after, he went to Mt. Vernon on business, in his right mind. When I first saw him, nearly every third pulse intermitted; in less than one hour after the first' appli- cation, they became regular." Rheumatism.—" A Mr. I., of Newark, had for years been occa- sionally afflicted by rheumatic pains. When I Avas first called to prescribe for him, he had labored eighteen days continually under a severe paroxysm of the disease. I applied the Liniment for rheu- matism three days, accompanied by Diaphoretic Drops and ner- vine tincture, which cured him of the complaint." Bronchocele.—" L. M.'s Avife of Clay Lick, has been afflicted for twenty years Avith bronchocele to such a degree, that she Avas unable to bend her neck, or look down on objects near her, and Avas much distressed in respiration. She applied the Stimulating Liniment, and gained much immediate relief. The SAvelling di- minished fast and at this time she is entirely free from the com- plaint." From Dr. G. B. Key, Portersville, Mississippi, Sept. 2d, 1836. Chills, Fever and Fits.—•" With regard to chills and fever, I have never failed in curing it by one or two applications of your Fever Liniment. It is very rare indeed that two applications have been necessary. " I cured one case of fits Avith the Nerve Liniment in two hours, Avithout any internal remedies, for the patient was rendered inca- pable of SAvalloAving by the severity of the disease. " With your remedies I can cure fevers in one-half the time that it Avill require by any other practice." Rheumatism, Liver Complaint, Dropsy and Tumefaction.— " I certify that my wife, aged sixty years, has been afflicted for 324 TESTIMONIAL. the last seven years Avith the liver complaint. The Avhole body became much swollen, and Avas severely afflicted Avith the rheu- matism ; her flesh drawn up into knots in different places ; joints stiff; soon after she Avas afflicted Avith the dropsy. With all the medicine I Avas able to procure, she obtained no more than tempo- rary relief. She became afflicted Avith large tumors on her shoul- ders, arms, knees and ankles ; a nervous affection, and bowels much out of order. In this situation, I applied Jewett's Stimula- ting Liniment on the whole surface of her body, at the rate of four ounces per week, for a considerable length of time, Avithout any sensible effect. I gave her diaphoretic poAvders, and, by the ap- plication of the Liniment for four Aveeks, I discovered the tumors became softer, and her dropsical affection Avas relieved. By a con- tinuation of these remedies, her tumors are at this time nearly gone, and her general health improved, with a fair prospect of enjoying a comfortable degree of health. Henry Pickerell, of Logan Co. Columbus, Sept. 6, 1836." From Dr. A. E., Newark, Ohio, Sept. 2, 1836. Chronic Diseases. Promotion of Equilibrium.—" In my practice, I have found your remedies the most ready in producing an equilibrium in the system that I have ever met with. In chro- nic diseases, Avhen the patient has been reduced to death's door; pulse hardly perceptible, and extremely slow, I have, by the ap- plication of your Liniments increased them thirty beats in a minute, in less than an hour : and, in other cases, Avhere the pulse ran to one hundred and twenty beats in a minute, I have, by the same process, reduced them to eighty, in six hours. Thus these reme- dies restore vital action Avith a readiness heretofore unknown in the. practice of medicine." From Dr. B. E., Salisbury, Meigs co., Ohio, Sept. 12, 1836. Chronic and Pulmonary Complaints, Fever, Pains, Phthi- sic and Dyspepsia.—" I have long been trying to get time to doc- BILIOUS FEVER, ETC. 325 tor myself for chronic complaints, the greatest of which is dyspep- sia. But a press of professional business compelled me to defer it until I was prostrated Avith the disease. The seventh day after I commenced applying your remedies, a breaking out appeared over the Avhole surface of my body, like the measles, Avhich I have no doubt Avas a humor Avhich has been my companion ever since I had the measles, when about twelve years old. This Avas the opinion of a very learned physician to Avhom I applied for advice. He called my complaint consumption, occasioned by the measles striking in. I have had a cough during my illness, probably from the same cause. NotAvithstanding the long standing of these com- plairits, I noAV consider them all broken up. My appetite is good, and I am gaining strength. Since I have been able to visit my pa- tients, I have applied your Liniments to a boy who was taken the day before with a high fever, Avhich continued intermitting until I saAV him. During the Avhole time he was almost choaking Avith phlegm, so much that it was distressing to be near him. I rubbed him with your Liniments from his head to his hips, and applied a plaster to his stomach, and betAveen his shoulders ; gave him some stimulating poAvders, and in a few minutes his respiration became easy, and in a short time after it caused him to vomit the phlegm from his stomach, and directly he called for food; and from that ime he has been entirely relieved. " A Mrs. Green, of this county, had been afflicted with pains in her side for many months. Her husband called on me. I gave him four ounces of Liniment, and I am assured it effected an im- mediate cure. " A daughter of Mr. Skinner, of Rutland tOAvnship, had been for a long time afflicted Avith the phthisic, and an eruption of the skin all over her body, Avhich they called the hives : and for several years had had the dyspepsia. The Liniment was applied, which Avas the only medicine relied on. I am informed by the father of the patient that the Liniment has cured her of all her complaints, and that she is now the most healthy child he has." From Dr. R> C, East Monroe, Ohio, October 5, 1836. Bilious Fever, Dyspepsia.—" There have been but three cases 326 TESTIMONIAL. of bilious feA'er, (all violent,) in this neighborhood of late. Two Avere treated Avith the usual practice, and one Avith your Liniment and Diaphoretic Drops. These two Avere four Aveeks getting up. The one treated with your remedies Avas Avell in three days. In that case, your drops Avere fully tested to my satisfaction. An in- veterate case of dyspepsia has been cured by the use of four oun- ces of Liniment and one bottle of Vegetable Syrup." From Dr. Jonathan Morris, Whiteley, Greene county, Pennsyl- vania, September 21, 1836. Suppressed Menstruation, Cholera Infantum, Liver Com- plaint, Head-ache, etc.'—" But a feAV Aveeks have elapsed since I was an eye Avitness to the good effects produced by your prepa- rations, particularly your Liniments, in a cure of obstructed men- struation, cholera infantum, liver complaint, head-ache, and many other complaints. They have been of great advantage to me in my practice. I Avas called to see a child laboring under the last stages of cholera infantum. All hopes of recovery Avere lost by the friends. I applied the Liniment to the thorax and the bot- toms of the feet, with some warming tea internally, and, in one hour, a change for the better was visible, and the child continued to mend, until restored to perfect health. I could give many more cases in which the good effect of the remedies was very apparent." From Dr. A. E., Newark, Ohio, November 1, 1836. Congestive Fever.—" Michael Edwards, aged ten years, was attacked with congestive fever. " Symptoms.—Cold chills ; pain in the head, back and limbs; flushes of heat; tongue livid, moist, and sometimes the appear- ance of thrush ; delirium, and entire prostration, Avithin six hours after the attack. " Treatment.—I applied the Fever Liniment on the whole sur- face of the body generally, and the Nerve Liniment an the head and spine; gave him stimulating draughts; placed hot bricks around him, and gave him the Diaphoretic Drops as per d'rections, LIVER COMPLAINT, ETC. 327 once ill twenty minutes. He was thrown into a perspiration, which Avas kept up for tAvo or three hours ; and the effect was, he Avas relieved from pain, his reason restored, and, in a degree, the fever arrested. After Avhich I caused him to be washed in a tub of hot water, and salt and Avater ; then applied the Liniment again. In about one day he Avas restored to health, though much weak- ened by the severity of the disease. Palpitation of the Heart and Vertigo.—" Mrs. Cruzen, of Licking county, Avas suddenly attacked with palpitation of the heart, and dizziness; and, in a few minutes, became blind and prostrated. There being no physician, and having some of your Liniment at hand, the friends applied it freely to the breast and spine; soon after she became sick at the stomach, and vomited freely, which caused a perspiration. She then fell into a gentle sleep, and on aAvaking the next morning, she was restored to health. Inflammation of the Urinary Canal.—" Andrew Lider had labored under an inflammation of the urinary vessels for more than a year; the pain attendant on voiding urine Avas most intense ; he became partially deranged. Every effort of medical aid had failed of giving relief, until I caused a general application of the Nerve Liniment on the back, spine, and in the region of the kid- neys, and the Stimulating Liniment, on plasters, low on the re- gion of the bowels, and on the perineum, relief Avas obtained. These applications Avere continued for four months, and the patient is now able to attend to business. Liver Complaint.—" Abraham Hall had been for some time af- flicted Avith a most severe affection of the liver ; extreme pain in the side and shoulder-blade ; languor ; much emaciation, and irregular- ity of the bowels. He had for a number of months been treated with various remedies, Avithout gaining any relief. I was called to pre- scribe for him, and adopted the following treatment: I gave him your Vegetable Syrup freely ; applied your Stimulating Liniment over his Avhole body twice a day ; next a plaster on the affected side ; gave him the Diaphoretic Drops freely, and placed hot bricks around him at night, which caused a perspiration. The case was so obstinate, that it became necessary to pursue this course for near- 328 TESTIMONIAL. ly tAvo months; he gradually recovered, and is noAV attending to his usual avocations." From Dr. A. E., September 26, 1836. Prolapsus Uteri.—" A lady in Coshocton county had been af- flicted Avith prolapsus uteri for six years. The symptoms were, nervous tremors, Avandering pains, general debility and gloomy sensations, Avhich are the usual attendants of this complaint. All efforts for relief had proven ineffectual, until I was called, and caused your Liniment to be applied on the lower part of the abdo- men, on her back and breast, with plasters of the same on the bot- toms of the feet. I then ordered her to make use of your Female Drops in half tea-spoonful doses three times a day. In about four Aveeks I salv her again Avhen she attested she was relieved. The whole expense of medicine for this extraordinary case Avas but about two dollars and fifty cents. Bronchocele.—"A Miss Shannon, of Licking county, had been afflicted Avith the above complaint for two years. Neck enlarged to tAvice its natural size; system emaciated, difficult respiration, so much so as to be obliged to be bolstered up in bed during the night, and unable to perform any labor. All previous prescrip- tions for relief had proved ineffectual. I was called. I ordered your Stimulating Liniment to be applied to the neck tAvo or three times a day, Avhich Avas done and continued for two months, and which entirely cured the complaint. She took some of your Veg- etable Syrup internally. Dyspepsia, Liver Complaint, Deranged Menstruation, and Quotidian Ague.—"A Miss Gosnell, of Licking county, had been severely afflicted with dyspepsia, liver complaint, and de- ranged menstruation, for nearly tAvo years, and when I was called to visit her, she had daily chflls and fever. I commenced by ap- plying your Liniment over the Avhole body once in tAvo days, at the same time applied the Liniment three or four times a day over the region of the pain, and applied plasters to the breast, bowels, back, and bottoms of the i'eet; and, at the same time, gave her your Diaphoretic Drops three times a day, at which periods I ap- plied hot bricks and threw her into a free perspiration. I also RHEUMATISM, ETC. 329 gave her your Vegetable Syrup. This course was pursued about six weeks, when the patient was entirely restored to health. Typhus Fever.—" A young man had been four days afflicted with an inflammatory fever. I was called and applied your Fever Liniment over the whole surface of the body, with hot bricks to his sides and feet, and gave him your Diaphoretic Drops accord- ing to directions, Avhich caused a profuse perspiration. The next morning he was up and free from fever. He took a walk, and when in a perspiration, Avashed himself in cold Avater, which threw him into a violent chill, followed by a fever of the typhoid type, delirium, wandering pains, and extreme restlessness. I com- menced by applying two ounces of Fever Liniment at once, gave him freely of the Diaphoretic Drops, and applied hot bricks to his feet and sides. This caused a profuse perspiration; in about three hours he was relieved, and the next morning he was in a state of convalescence, and in a feAV days was able to attend to bu- siness." From Rev. Jeremiah Hill, Muskingum county, October 14, 1836. Dyspepsia, Head-ache, Pain in the Breast, and Bite of the Copperhead.—"I have found your Liniment very beneficial to me for pain in the breast, Avith Avhich I have been afflicted. I have used it considerably on others, with good success, especially in head-ache. In one instance I found it successful in curing a se- vere bite of a copperhead snake. Having had occasion to travel considerably, in connection Avith the use of your Liniment, my health has been greatly improved, and dyspepsia cured." From Thomas C. Lewis, Esq., Portsmouth, Ohio, October 15, 1836. Rheumatism, and Suspended Animation by Drowning.—" I have proven the efficacy of your remedies in several instances, one of which was a case of rheumatism in the knees. The Lini- ment was rubbed on, and a small quantity of the Diaphoretic Drops 42 330 TESTIMONIAL. given internally, Avhich cured the patient. Another Avas the bring- ing to life of a boy of Mr. Clugston's AVatch-maker, of this place, Avho had been droAvned by the sinking of a skiff in which he, Avith some other boys, Avas taking an excursion. When taken from the Avater he was entirely senseless and apparently dead. I applied your Liniment, and in fifteen minutes animation returned and he was in a profuse perspiration." From Dr. Jonathan Morris, Wliitely, Pennsylvania, October 17, 1835. Bilious Cholic, Scarlet Fever.—"I congratulate you on be- ing so happy as to apply your preparation to the afflicted, and the effects thereof producing immediate relief. Last week I had one case of bilious cholic in a lady who had been subject to it. I had relieved her several times, but all medicines seemed to fail of curing, until your Stimulating Liniment was applied to the feet, Avrists, thorax, and abdomen, Avith friction. In two hours she was relieved. Also, in the scarlet fever, I have seen its salutary effects verified. Your invaluable medicines are far superior to any I have tried." From E. C. Keckley, M. D., Charleston, S. C, October 25, 1836. Cholera, Sciatica, Swelling of the Jaw, Piles.—" I have used your Stimulating Liniment in cholera. I found it to answer my greatest expectations. I found no difficulty in relieving cramps with it. It is excellent; it is superior to any other article which I have tried. I have used it in as severe a case of sciatica as I ever saw, in an old negro, with complete success, after five or six rub- bings. Indeed the first rubbing produced comparative ease. I have used it in a sAvelling of the jaAv, from a decayed tooth, with suc- cess, after a few rubbings. The jaws were completely locked. So far as I have used your remedies, I have succeeded. I can now recommend them with confidence. Your pile salve suc- ceeded in two cases of not very long standing. PILES, ETC. 331 From Dr. J. B. C, Big Prairy, Wayne county, Ohio, Novem- ber 2, 1836. Fits, Fever, Intermittent Fever, Head-ache, Sprains, Bruises, and Pains.—"As to the efficacy of your Liniments, I have used them in two cases of fits, two cases of fever and ague, several cases of fever, sprains, bruises, head-ache, and pains of all kinds; and have found them excellent remedies for the afflicted, giving almost immediate relief in the most acute forms; and I am fully confident that in chronic complaints, which have progressed so far as to render an entire cure uncertain, relief may be obtained, and many lingering diseases perfectly cured. Not long since, I was called to visit Catharine Wells, of Clinton tOAvnship, Wayne county, Avho was afflicted with fits. When I entered the room, the spasms Avere so violent that it required three men to hold her on the bed. She had been in the paroxysm six hours. I applied your Liniment to her temples, thorax and soles of the feet; gave her a tea-spoonful of your Diaphoretic Drops, and in fifty minutes she was entirely relieved, and next day about her work." From Dr. S. D., Sandy Creek, New-York, November 3, 1836. Hemorrhage from the Lungs.—"If I had had time, I should have Avritten to you before, concerning the wonderful effects of your Liniments in many cases. By the use of them I have saved many cases that were given over to die; especially one of bleeding at the lungs. The patient had suffered with it for eighteen months; had been bled once in two or three places to stop the pressure at the lungs. He discharged a large quantity at a time. When I began Avith him, I was told that I might as Avell go to the grave- yard for a patient as to try to cure him. But, by the use of the Liniment and the other remedies, his health is entirely restored, to the astonishment of all his friends." From D. J, Dayton, Ohio, Nov. 17, 1836. Piles.— " Henry Walker, of Beaver township, Greene county, 332 TESTIMONIAL. Avas afflicted Avith piles for upAvards of twenty years, for Avhich he applied every thing he heard recommended for that complaint, and got no relief. Last April he applied to me. I gave him a box of your Pile Salve, about half of Avhich completely relieved him; he remains well to this day." I certify that the above statement of D. J. is correct and true. Henry Walker. Certified on the 5th November. From Dr. T. N., Xenia, Ohio, Nov. 17, 1836. "As for your Liniments and Cerates, I cannot extol them too highly. I have successfully treated the folloAving cases with them since I was Avith you, viz: hydrocephalus, fluor albus, fevers, worms, uterine diseases, milk-sickness, dyspepsia, measles, pleu- risy, piles, rheumatism, diseases of the urinary functions, pains, irregular menstruation, pulmonary complaints, aphtha, flux, poly- pi, erysipelas, wens, jaundice, etc." Frcm Dr. D. H. Union, Morgan county, Geo., Nov. 16, 1836. " On the 6th of August, I obtained a hundred dollars worth of your preparations. In one month, I administered to seventy-three patients, Avith good effect. Of these, fifty-eight cases Avere fever, six midwifery, two asthma, two kings-evil, two rheumatism, one dropsy, one consumption, and one broken limb; and they are all restored to health. I am entirely out of your remedies; and now I realize their value more than when I had them. I feel it a mat- ter of much importance to possess the means of lessening the suf- fering of the human family, in so high a degree as I have found your remedies to do. I can safely recommend them to the public. They have so far exceeded my anticipations, that I cannot practice without them; and I find that, with the aid of your Liniment, I can attend to more patients than myself and partner could last year." CONSUMPTION, ETC. 333 From Dr. D. H. M., Paris, Ky., Nov. 24, 1836. " I have used your preparations in at least one hundred cases since I obtained them last summer, and I do not recollect a single instance in which there was not a decided benefit derived from them; and in many instances, instantaneous relief was obtained. Your Head-ache Liniment is very notorious; I have had calls for it more than fifty miles from this place. Its virtues have been fairly tested in this section. One or two applications have suc- ceeded in curing the most inveterate cases I have ever been ac- quainted with. I am equally pleased with all your preparations, and I could say as much for all, as for the Head-ache. I cured a case of scald-head of nine or ten years' standing, with two appli- cations of Cerate, and one of Tetter Salve." From Dr. M. McC, Clear Spring, Maryland, Nov. 30, 1836. Dysentery, etc.—"A few months ago I procured a few bottles of your Liniments, and applied them in several cases with great success. The first, a small child, who, from its infancy, had not enjoyed one hour of good health, was perfectly cured, and is now one of the most healthy of the family. I have also cured cases of dysentery, with your remedies, in a few hours." From Dr. A. W., Rome, Tenn., Dec. 2, 1836. " I purchased two bottles of your Liniments, and gave them a trial on my son, who was very low with an inflammation of the lungs. A few applications of your Liniment, with a dose of phy- sic, quite relieved him, and he is now in good health from these applications." Consumption.—Mr. Randolph Elliott, a planter from the State of Mississippi, came to Columbus in September last, and applied to us for relief from a pulmonary complaint, with which he had been afflicted for thirteen years. When he arrived in this city, he 334 TESTIMONIAL. Avas much emaciated—so much, that frequently he was unable to Avalk any distance, after being seated for some time: he had ex- treme Aveakness in his joints, SAvelled ankles, hectic cough, and pain in the left hypochondriac region. We applied our remedies for five weeks, in Avhich space of time his health was nearly re- stored, his cough had left him, he had strength to Avalk several miles Avithout any tremulousness, and he returned home with full confidence that a continued application Avould restore him to per- fect health. The beneficial operations of the remedies in this case Avere so apparent, that the excretion of morbific matter by the ex- halants was astonishingly facilitated, and Avas perceptible on the linen. |Q° We have since received a letter from this gentleman, stat- ing that his appearance was so much improved, on reaching home, that some of his most intimate acquaintances scarcely knew him. Mr. Carlos Barnes, from Michigan, came to this city about the middle of November, for the purpose of placing himself under our treatment. He was afflicted with stiffness and soreness in the joints of the lower extremities, with a very perceptible creaking Avhenever they were moved, and the feet palsied, occasioned by the inflammatory rheumatism, with which he was attacked five years ago. Last fall he was attacked with intermittent fever of the tertian species, which gave a desperate shock to his system, and brought on a consumptive cough, Avith profuse evacuations of blood from the lungs, and general emaciation. In about ten days from the commencement of our prescriptions, his cough was re- lieved, his general health much improved, the synovial membranes of the joints relaxed, and he, also, left us with full confidence that a continuation of the same treatment would restore him to health. Both the above gentlemen assured us they had tried, without suc- cess, every other means within their reach. I have been afflicted with the inflammatory rheumatism for six years. About two months ago, I was taken more severely than usual. I was confined to my bed for two weeks, without being CHILLS AND FEVER, ETC. 335 able to gain any permanent relief. I was also afflicted Avith a se- vere cough, loss of appetite, cold chills, and sick stomach. The rheumatic affection became most distressing in my breast. From all these afflictions I have been relieved by an application of Jew- ett's Liniment, worn on plasters which covered my breast, sides, and back, and the bottoms of my feet. In two days after I ap- plied it, my cough was relieved, my appetite returned, and in about a week I Avas able to attend to business. This relief was obtained without the exhibition of any internal medicine. C. M. Smith. Columbus, Feb. 21, 1837. Chills and Fever, Obstructed Menstruation, Mental De- rangement.'—About two months ago, a daughter of S. Thomson, of Fayette county, was severely attacked with chills and fever, and obstructed menstruation, and extreme pains in the back and limbs. After having been bled freely, she became delirious, and remained for four days the most distressed object imaginable. When I was first called to her, I administered three doses of your Diaphoretic Drops, applied plasters of the Stimulating Liniment to her neck, bowels, and feet, and rubbed her generally with the Liniment, and put hot stones to her feet, back, and bowels. In a short time, she was thrown into a profuse perspiration, which gave her relief, and in a few hours her reason returned, when she was relieved from pain. The next day found her able to rise from the bed, and in less than a week restored to perfect health. Edward Stubblefield. Fayette county, January 19, 1837. Remark.—We have had under our own treatment, and reported to us, a vast number of cases of female complaints, in all their va- rious distressing forms, wherein our remedies have proven effica- cious in a high degree. Indeed, we have not known a failure. But we have found it extremely difficult to give publicity to the cases reported. Were the fact known, that a sure and sovereign reme- dy is discovered for those complaints, thousands of valuable fe- males who are at this time laboring under uterine affections, Avould find means to obtain the remedies for their relief. 336 testimonial. A case has recently come under our treatment, in this city, of a lady who Avas reduced to the verge of the grave by excessive he- morrhage, Avho Avas almost instantly relieved by the application of our Stimulating Liniment, and the Vegetable Syrup, and in a few days Avas restored to health. Incurvation of the Spine—Affection of the Heart and Breast.—Four years ago, I became afflicted in the back, Avith se- vere pains in the region of the spine ; from thence, it appeared in my sides and at the termination of the breast bone. About eigh- teen months after suffering as above stated, the distress settled about the heart and breast. For a long period, I experienced a sharp piercing pain, once in eight or ten minutes, through the heart, terminating in the right side, that could not have been more severe had a knife pierced my body. Tavo years after I had been thus afflicted, an incurvation of the spine took place, by which I was drawn down, and the back bone enormously distended with severe pain. These afflictions Avere attended by general debility, and continued for more than three years. Having despaired of any relief, for all means tried had failed, I heard of Jewett's reme- dies, and, as a last resort, procured some. I applied his Stimula- ting Liniment for a considerable length of time, accompanied with his Vegetable Syrup and Diaphoretic Drops. I directly found re- lief, and continued to mend, so that, at this time, my general health is good, my back is nearly straight, and I have done more labor since my relief than for eight years before. David Culp. Columbus, February 1, 1837. From Jonathan Morris, M. D., Wliitely, Green county, Pa., De- cember 16, 1836. Bilious Colic—Cholera Infantum.—"I have proven your Liniments in bilious cholic, cholera infantum, and many other forms of disease, to my satisfaction. They are far superior to any remedies I have heretofore known. NERVOUS AFFECTIONS, ETC. 337 From Dr. A. W', Rome, Tennessee, December 2, 1836. Inflammation of the Lungs.—,, I procured tAvo bottles of your Liniment, and applied it on my son, who was very low with an inflammation of the lungs, which relieved him; and noAV, three Aveeks after the first application, he is enjoying good health." From Dr. A. E., Pleasant Hill, Coshocton county, December 4, 1836. Nervous Affections —" A lady of this county has recently come under my treatment, who had been confined in bed for two months, with general emaciation ; prostration of the nervous system ; lum- bago ; constipation of the bowels; wandering pains; and, fre- quently, flashes of fever. She had been treated, during the above period, by the most skillful physicians in the county, all of whom pronounced her recovery hopeless. I Avas called, and applied your remedies, Avhich threw her into a state of convalescence in a few days ; and, in a few days more, she was able to start on a journey to Virginia. Numb Palsy.—" Another case has recently come under my treat- ment where the efficacy of your remedies proved all-powerful. A lady, of rather slender habit, took cold some time last summer: soon after, she became perfectly stupid, and almost insensible; her left side and left eye Avere apparently dead, cold, unnatural, and helpless, though she breathed freely ; her pulse strong, irregu- lar, and vibrating. In this distressed situation, she remained two or three months. When I was called, I applied your remedies freely ; left her a good supply, Avith directions ; and when 1 visi- ted her again, a week after, to my utter astonishment, I found her convalescent. In this case, about ten ounces of Liniment was used in a Aveek. From my own experience, I do not believe that one case in a thousand Avould fail if your remedies were freely applied." N. B.—Both ladies, above mentioned, enjoy good health, and are perfectly free from all disease. 43 338 TESTIMONIAL. From Dr. J. J. Foster, Pinckneyville, S. C, January 4, 1837. Hemorrhage, Prolapsus Uteri, Fever.—,, I am happy to in- form you that, so far as I have used your remedies, they have been attended with general good success. In an hour or two, I arrested a hemorrhage, occasioned by a fall from a horse, in a lady, who expected an abortion by the accident. Another : a case of prolap- sus uteri Avas cured by the Liniment and Stimulating PoAvders, in Avhich case the Liniment Avas repeated three times a day. A com- plete cure was effected.* I have used your Liniments in fevers freely, Avith good success. A negro man had had a fever for a Aveek Avithout medical aid: I found him helpless and deranged; he had been so for thirty-six hours. I repeated the Liniments, each three hours, over the Avhole surface of the body; gave Sti- mulating poAvders every half hour; and, in tAvo hours from the first application, he was in a free perspiration, and, in an hour more, discharged freely from the stomach and bowels, and Avas in his right mind. I continued the above course. No other medi- cine Avas made use of, and he was able to set up the next day; he got well shortly after. A girl in the same family had the fever: she Avould not take any medicine, internally, at all; but, by the application of the Liniment alone, Avas cured of the fever in twen- ty-four hours, so that she has had no return of it. Her tongue be- came clear, her appetite good, and she is perfectly well." From Dr. John Steele, Frankford, Missouri, February 26, 1837. St. Vitus Dance.—" I have had one case of St. Vitus' dance since I last Avrote you,—a young man about seventeen years old, whose left arm, leg, and thigh Avere greatly affected—his mental functions Avere much impaired, attended Avith symptoms of con- sumption. I brought him to my house, and commenced the treat- ment of his case by giving him diaphoretic tea, and on the second day an emetic, at the same time making use of your Nerve and Consumption Liniments. The fourth day, I used a vapor bath, * It is now no longer an experiment; thousands have been cured, who, until of late, had no other prospect than to "linger in pain" all their days. BOWEL COMPLAINT, ETC. 339 etc., still using the Liniments. As soon as this was done, he came to his proper mind, the spasms were allayed, except a slight moving in his hand, which continued for a feAV days. He has been here two weeks; has been mending every day, and is now well." From William P. Payne, Esq., Flat Rock, Ky., January 8, 1837. Cholera, Malformation of the Heart.—" More than two years ago, I gave you a statement of my afflicted child, of seven years old. He was, as Avas thought, a blue child. The most learned physicians pronounced it a malformation about the heart, or obstruction in the ventricles. All the faculty who examined him pronounced his case incurable. I applied your Stimulating Liniment to the child, and placed plasters over the region of the heart—dressed him with flannel shirts, and continued this course until his skin became tender, when I discontinued the application. From the use of the Liniment, his health is greatly improved, so much that Ave have ceased giving him any thing in the way of medicine. In the summer of 1835, the spasmodic cholera visited us. This same boy was attacked very bad : I gave him stimula- ting medicine internally; rubbed him with the same over the sur- face of the body, and then, with your Liniment, applied a plaster of the same over his stomach and boAvels ; applied hot bricks to his sides and feet. In twenty minutes, the rice water discharges were checked entirely, and in two hours he was up and about the house. His eyes had sunk, his features distorted, his skin shrunk, before I could produce a reaction ; but his recovery was instanta- neous. One of my servants, who was unable to labor more than half the time, has, by the application of your Liniment, been greatly improved " From John Naylor, Esq., St. Charles county, Missouri, Jan- uary 9, 1837. " I would suggest the propriety of an arrangement for a deposit 340 testimonial. of Jewett's Remedies in this State, if there be not already such an arrangement made. I the more readily recommend the above from the fact of having received relief by the Liniment myself. In de- scending the Ohio river in July, 1835, in a steam-boat, I experi- enced a severe attack of the stomach and boAvel complaint. A gen- tleman on board recommended and furnished me Avith some of the Liniment, the application of which had an immediate salutary ef- fect. In experiments made since, Avith the same medicine, I have always found it proved beneficial." Remark.—Were every boat that descends the Mississippi fur- nished Avith our Liniments, a vast amount of human suffering Avould be mitigated. The application is so simple, and the relief so ready, that it would seem to be designed peculiarly for sailors. We knoAv of many Avho will not sail Avithout it. From Dr. Aaron Edwards, Pleasant Hill, Coshocton county, January 10, 1837. Congestive Fever.—"A daughter of a Mr. Nichols, of Lick- ing county, was attacked in November last, Avith congestive fever. The symptoms Avere, pain in the head, back and limbs; cold chills in the back; cold extremities; convulsive tAvitchings in the limbs, accompanied with a burning fever; delirium; eyes protruded; tongue moist, with a red appearance through a milky coat of white. In fact, every symptom indicated sudden dissolution. About tAventy-four hours after the attack, I Avas called to prescribe. I applied the saline vapor bath, with a free use of the flesh brush, and friction Avith the hand; caused your Fever Liniment to be ap- plied over the Avhole surface of the body, and applied hot bricks to her feet and sides; gave her Diaphoretic Drops, Avhich caused a free perspiration in a few minutes, Avhich appeared to arrest the disease at once, for she became convalescent in a few hours. Two days after, finding some lingerings of the fever, I applied the same course to her again, Avhich restored her to perfect health in three days. Whooping Cough.—" One of my own children was attacked a feAV days since Avith the Avhooping cough. I prescribed no medi- FITS, RHEUMATISM, ETC. 341 cine for him for several days, when I applied your Cough Lini- ment to his neck, back, breast, and the bottoms of his feet, which at once stopped his Avhooping. In three hours after, I made a general application of the same Liniment, and the third time I ap- plied it, he was entirely relieved of the complaint, and it has not returned on him. Pains in the Breast, Sickness at the Stomach, and Loss of Appetite.—"A young lady in Roscoe Avas severely afflicted Avith pains in the breast, sickness at the stomach, and loss of appe- tite. She was perfectly cured by one application of your Stimu- lating Liniment. In this case the Liniment Avas very freely ap- plied to the stomach, which caused vomiting equal to that of an emetic. Case of Puerperal Fever.—"In October last, the Avife of John Miller, of Licking county, Avas brought to bed, and the pla- centa was removed by force; orthopncea; located inflammation, and distension of the abdominal and uterine parts. In this situation, she took a violent cold, when she became stupid; hot fever; wan- dering pains, particularly in the uterine region. When I Avas called, I first commenced by applying the Nerve Liniment freely over the Avhole surface of the body, three times in twenty-four hours, and gave her freely of the Diaphoretic Drops, which soon caused a free perspiration, and she became more sensible, Avhen her friends thought her to be dying. She, hoAvever, soon became convalescent. The same course Avas repeated, Avhich entirely cured her in a feAV days, and she is noAV in good health." From Rev. B. R., Fayette county, Ohio, January 16, 1837. Fits and Rheumatism.—"After administering your remedies for nearly one year, in a'great variety of cases of the most obsti- nate and unyielding nature, with unparalleled success, it is due to the public, and to suffering humanity, that I state some more rare cases, Avhich have been successfully treated by me. The wife of Thomas Jones, of this county, had been afflicted for nearly three years Avith epileptic fits, occasioned by previous female complaints. 342 TESTIMONIAL. I applied your Nerve Liniment about the head, neck and the Avhole length of the spine, Avhich relieved her in about tAvo Aveeks. I Avill mention a case of rheumatism. Joseph Heaton had been afflicted more than tAvo years Avith pains in the arms, legs, hips and joints generally, Avhich became so severe about his thigh that it Avas draAvn out of the socket. I made a full application of your Liniment for Rheumatism over his Avhole body, applying it more freely about the disjointed hip, and in less than tAvo Aveeks his pains Avere removed, the tension of the muscles about the thigh became so relaxed that it returned to its socket, and at this time he is in perfect health." From Dr. T. S. M., Athens, Georgia, January 16, 1837. Bruise, Piles, and Constipation of the Boavels.—The small amount of your remedies I have obtained has done Avonders. A gentleman by the name of Wilson, in getting out of his wagon, fell and bruised his ankle very much. It became SAvollen to a great size. He used your Liniment three times, and it entirely relieved him. A Mr. Davis had had the piles for a number of years, Avith constipation of the boAvels. I applied your Pile Salve; gave him your Diaphoretic Drops, and he is now willing to testify that he is in better health than he has been for years. I have met Avith equal success in fever cases, rheumatism, etc." From Rev. John Clark, College Farm, near Lawrenceburg, la., January 23, 1837. "AHoav me, in the first place, thankfully'to acknowledge the re- ceipt of your medicines, a favor that has brought me under an obligation of which I am not insensible. They have ansAvered, I think, fully equal to your OAvn expectations, and far exceeded mine. I have not been afflicted Avith piles in the slightest degree, since a short time after I received the Salve. From several I have received thankful acknoAvledgments of the instant relief obtained from head-ache and rheumatic affections, by an application of the Liniment. In my own family they have been of great service." CHRONIC COMPLAINTS, ETC. 343 From Dr. R. S. G., New-Castle, Henry county, Kentucky, Jan- uary 25, 1837. Fever, Colic, Pleurisy, etc—"I have applied your Lini- ments in fevers, colic, pleurisy, sore throat, pains in the joints, and head-ache, and found all that was necessary Avas but one or two rubbings, and if they ever fail, it is because! they are not ap- plied according to your directions. Your Cough Liniment is a most invaluable preparation. Some time since, I took cold from great exposure, which settled on my lungs. I applied this Lini- ment three nights by the fire, just before retiring to rest; and I am well. Your Diaphoretic Drops, Syrup, Pectoral Drops, Cerate, and Liniment for Rheumatism, I have found equally efficacious in the diseases for which they are intended." From Dr. N. Berry, Reedy Fork, S. C, February 1, 1837. Rheumatism.—" Your remedies have far exceeded my most sanguine expectations. In a case of rheumatism, I have witness- a cure where every other prescription failed. Sick head-ache, bowel complaints, pains in the back, sprains, etc., have been readily cured, much to the satisfaction of the patients and their friends. Chronic Complaints.—" I was called a few days ago, to visit a lady thought to be dying, by the name of Michen. When I arrived, the family were in great distress, holding her up by the side of the bed, hathing her feet in Avarm Avater; she appeared to be in the last agonies of death. Her pulse had ceased to beat; her jaws were set, and of course she Avas speechless. I had Avith me four ounces of your Liniment, Avhich I directed to be imme- diately applied. Six ladies commenced rubbing on the Liniment; two on her feet and legs, two on her hands and arms, one on her breast and jaAVS, and one on her back and between her shoulders. In twenty-five minutes she recovered and spoke, and assured us that at the commencement of applying the Liniment, her eye- sight and hearing Avere nearly gone. I am happy to say she is still mending. Her disease has been chronic, of long standing. 344 TESTIMONIAL. It Avill be proper here to state, that as soon as she Avas able to swallow, I gave her your Diaphoretic Drops freely, and placed hot stones at her feet and sides. So far was nature sunk, that no perspiration could be raised for a long time; her flesh Avas cold; the blood had ceased in a measure to circulate. One of the ladies Avho administered to her relief, declared she felt during the time, as if she was attempting to restore the dead to life. She is now in the enjoyment of perfect health." From Rev. R. McDaniel, M. D., Paris, III, February 3, 1837. " I am happy to state, Avith regard to your remedies, and their curative qualities, that my acquaintance Avith them has been suffi- cient to enable me to bear decided and unequivocal testimony in favor of their excellency in affording prompt and permanent re- lief, Avhen properly applied, in fever, scrofula, bowel complaint, pleurisy, head-ache, uterine hemorrhage, etc.; and as to the ex- pense, Avhich some interested individuals have attempted to make a scare crow, it certainly does not exceed that of prepared medi- cine generally, especially Avhen all the important advantages are taken into account." From Dr. J. W. B. T., Perry town, Harrison county, Va., February 24, 1837. pILES.—" About tAvo years ago I was troubled very much with the piles, and was for a long time seeking for relief, but without success, until I obtained your Pile Salve, a few applications of Avhich afforded me entire ease, and I was apparently free from the disease. No symptom of it appeared for four months, when I felt a slight attack. I again applied the Salve, one application of which entirely cured me, and I have not been troubled with it since. Out of the same bottle, I supplied a gentleman who had been afflicted Avith the same complaint for a great number of years. He Avas frequently unable to ride on horseback, or attend to busi- ness. He had but about one thimble full, which he used, and he now informs me that he is entirely Avell." FEVER LINIMENT, ETC. 345 Rheumatism.—" My brother-in-law has been using your Lini- ment for Rheumatism. He had been afflicted very severely with that complaint, and by an application of the Liniment for two weeks, has effected an entire cure." From Drs. Warren and Shelly, New Market, East Tennessee, February, 12, 1837. " Your invaluable remedies have acquired a distinguished repu- tation, so far as the use of them extends. In relation to our own particular knowledge of their efficacy, we are proud to say, that we believe no account we have seen published in the Advertiser, surpasses its true merit. In no place have we applied the Lini- ments, where there Avas not more or less benefit derived therefrom. In some instances, Avhere all other remedies failed, it has succeed- ed beyond our most sanguine expectations. Your Fever Lini- ment is truly astonishing in its effects. Please explain, in your next Advertiser, its principle of action, in so quickly regulating the pulse, and changing feverish excitement, in all febrile diseases." Remark.—The above inquiry may be answered in the lan- guage of an eminent scientific physician, whose extensive practice with our Liniment for Fever, has elicited the folloAving remarks : " Your Fever Liniment, being an extensive composition of highly concentrated therapeutical agents, containing stimulating, tonic, diaphoretic, cathartic, emetic, and nervine qualities, all of them so nicely balanced, that when the stimulants and diaphoretics cause a free perspiration, and extensive discharges of morbific matter, the tonics support the system, and the patient retains his usual strength through the operation. If the mucus membrane of the stomach be coated, the same remedy Avill readily remove this obstruction, causing it to pass off through the intestinal canal. If the stomach be bilious, a full application of the Liniment to the pit of the same, with warm cloths applied, will cause gentle vo- miting, and the stomach is relieved. If the bowels have become constipated, and are inclined to inflammation, the stimulating and purgative qualities of the Liniment, give action to the boAvels, caus- ing free discharges from the same, and the patient is relieved with- out being subjected to a long state of convalesence." 44 346 TESTIMONIAL. From Dr. A. D. " A NEW MODE OF APPLYING YOUR HEAD-ACHE LlNIMENT.—I have been attending a lady Avho has, for a number of years, been laboring under a complication of chronic complaints of the worst character, and among them was the sick head-ache. She became relieved of all her difficulties, excepting an occasional return, in a slight degree, of the head-ache. She applied the Liniment upon the inside of the nose, and though it was pungent and a little pain- ful at first, she Avas entirely relieved in five minutes, and she has ever since been entirely free from the disease." From E. C. Keckeley, M. D., Charleston, S. C, Feb. 12, 1837. " I used your Consumption Liniment in a case of spitting of blood, with a disposition to consumption. I used about one half an ounce Avith so much relief, that the patient, on leaving town, requested some to carry with him. In rheumatic compaints, your Liniments are superior to anything I ever tried. For pains of every description, they are excellent; I find no difficulty in speed- ily relieving them by your Liniments. I have used your Vege- table Cerate in a case of sore nipples, Avith complete success in a day or tAvo. It is excellent for eruptions on the skin, ringworms, etc." From Dr. T. F. D., Adrian, Michigan, February 18, 1837. Bowel Complaint.—-" I have been in the use of your remedies for the last six months, with the most satisfactory results. I will mention one remarkable case of a child of two and a half years old, afflicted with the bowel complaint. This child Avas treated at first in the usual practice of calomel and astringents, without bene- fit, until the physician pronounced the case incurable. When I was called, I made use of such remedies as I have usually prescri- bed in such cases, for six days, when the physician who first at- tended her, gave an opinion that death would terminate the dis- tressing scene in tAvo or three days. Just at this time I obtained some of your Liniments. The first application produced a bene- ASTHMA, ETC. 347 ficial effect, to the astonishment of all the friends, and by a contin- uation of the same remedy a few weeks, the child was perfectly cured." Remark.—Had Dr. D. been in possession of our Liniment for cholera morbus, and applied it according to directions, the relief Avould have been much more ready. We have never known a case where an entire cure was not effected in one or two days, if this Liniment had been freely applied. From Mr. A. Stockbarger, Licking county, Ohio, January, 1837. Piles Cured.—" I have been afflicted with the piles for twelve months severely every day, from which I have been relieved by JeAvett's Pile Salve. I never had a return of the complaint after the first application." From Caleb Brooks, Esq., Licking county, February, 1837. Pleurisy.'—■" My wife was attacked about the 12th of this month with a pleuritic affection very severely, pains in the shoul- ders, etc. She was in the most distressed condition imaginable. Jewett's Stimulating Liniment was applied to her side and shoul- ders freely, accompanied with the use of the Diaphoretic Drops, and in one hour she was relieved from the complaint; no other remedies were made use of." From Major Alexander M. Allen, of Jefferson county. Geo. Cases of Asthma, Cough and Fever.—" I have used Jewett's Stimulating Liniment for the asthma and a severe cough, and have found them to produce very great relief, being more prompt and efficacious than any remedies I have before used, having speed- ily caused a complete cessation of the diseases. I have witnessed the beneficial effects of Jewett's Fever Liniment in relieving my daughter from an intermittent fever of long standing, and restoring 348 TESTIMONIAL. her to a greater degree of health and strength than she has enjoy- ed in some months. Feb. 25, 1837." From Mr. Jeremiah Vinson, of Burke county, Virginia. Case of Fever and Ague, axd Pleurisy.—" In December last, I Avas taken with a severe ague, pain in the breast, and cough, Avith a high fever, which continued, but moderated just before the period of the chill, which occurred every day. " I Avas in this situation one week, the Avhole of the symptoms becoming more severe and distressing, when I made use of Jew- ett's Liniment for Fever, according to the directions, which pro- duced a profuse perspiration, and continued so for some hours, which relieved all the symptoms, mitigated the cough,' entirely re- moved the pain in the breast, and completely overcame the fever, which never returned ; a continued use of the Liniment for several days entirely removed the remaining cough, and restored me to entire health, Avhich I continue to enjoy. February 23, 1837." From Dr. Thomas M. Henley, Walkertown, Virginia, January, 1837. " I had, during the last fall, about eighty patients, with different diseases, in Avhich cases I used your Liniments, accompanied with internal stimulating medicine. Out of this number I lost but two small children, neither of whom were treated with your reme- dies. I was at once enabled to arrest the fever with these agents. I can with confidence say, your remedies are harmless in their operation, relieving pains of all kinds at once, and they produce a pleasant operation when properly applied." From Dr. S. P. Pool, Mecklenburg county, Virginia, February 16, 1837. "I have procured and used a small quantity of your medical preparations, and every person who has tested them, is highly CROUP, ETC. 349 pleased with the effects produced by them. My Avife, who was on the verge of the grave with a liver complaint, has been relieved by them." From Dr. John Steele, Frankford, Missouri, February 26, 1837. " Had I room I could give many names that Avould give certifi- cates to the good effects of using your remedies ; but it is enough, or ought to be enough, for the people to know that wherever your remedies are used, the demand becomes great." From J. J. Moorman, Esq., Highland county, Ohio, February 16, 1837. Tumors, Bronchocele.'—" I have been using your Liniments in my family for more than a year, and have uniformly received the most decided advantage therefrom. My wife had lumps on her eye-lids, which were pronounced by the physicians as incura- ble by any other method than being cut out. I applied your Lin- iments to these tumors for three weeks, which removed them en- tirely. Before she made the application, it was with difficulty she could open her eyes. My mother has been afflicted with a bronchocele for ten years; neck much enlarged. She applied your Stimulating Liniment for a considerable length of time, which has reduced the enlargement, and she is now perfectly re- lieved from the complaint." From the Rev. Wm. Dale, Alexandria, Tennessee, March 6, 1837. Croup.—" I received a small portion of your Sttmulating Lini- ment from a friend. My daughter's youngest son, a fine, fleshy, child about a year old, was taken ill Avith croup, and, her hus- band being from home, she became very much alarmed, and came with all haste, with her son, to my house, expecting he would die on the way. I directed her to bathe his feet in warm water, and I then applied the Liniment to the bottoms of his feet, and to his 350 TESTIMONIAL. throat and stomach, Avhich produced a considerable perspiration ; and the happy result Avas, he obtained immediate relief. The next day, on returning home, the child took cold, and the croup return- ed very bad. She made a similar application, and the like happy results folloAved. Another daughter of mine Avas taken Avith the cholera morbus, Avhich produced a severe pain across the abdomen, and cramped her dreadfully. She got no relief until I directed an application of the Liniment to the affected part. Immediate relief wa3 obtained. A son, from Florida, lately returned from the Se- minole Avar, had a very bad pain in the left side of his breast; only two light applications removed it entirely. And I have found re- lief, myself, from the dreadful pain in my head." From Joseph Nollner, M. D., and L. P. Portlock, Norfolk, Virginia, March 9, 1837. " Having frequently used yeur Liniments, etc., and clearly test- ed their medicinal virtues in curing head-ache, back-ache, colic, fevers, hip-joint affections, rheumatism, cuts, bruises, etc., we do not hesitate to recommend them to the afflicted as safe remedies." From Dr. Thomas Nash, Norfolk, Va., March 9, 1837.' " I dare say nought against your medical remedies which have so often proved highly valuable and worthy of the character which they bear, Avhenever they have been faithfully and properly ap- plied. I should do you great injustice were I to withhold my testimony in favor of your preparations for external use." From James B. McCord, M. D., Richmond, Ray county, Mo., March, 1837. Bilious Spasmodic Colic—" Among the many cures which have been favorably effected Avith your remedies, I wish to state one of bilious spasmodic colic which took place under my own observation. A young man was attacked with pains and cramps, MENTAL DERANGEMENT, ETC. 351 in his bowels, of the most extraordinary nature. He remained in this situation from Monday until Wednesday, when an applica- tion of your Liniment was made to his bowels, and one potion of Diaphoretic Drops were exhibited, which gave relief quickly, and the next day he Avas in sound health, though much weakened; no other medicine Avas made use of." From Mr. William Moore, of Burke county, April 4, 1837. Case of Fever, Liver Affection, and Pleurisy.—" I have been in bad health for several years past, particularly by periodi- cal attacks of fever and ague in the fall seasons, which left a seat- ed affection of the liver and enlargement of the spleen. I was at- tacked, in January last, with chill and fever, attended with a vio- lent cough and severe pain in the breast. I made application of JeAvett's Liniment for fever, Avhich entirely relieved the chill and fever, removed the pain in the breast, and eased the cough, both of which occasionally returned; but a continued use of the Lini- ment for about one week performed an entire cure of those symp- toms, and restored me to ordinary health; a further use of Jewett's Stimulating Liniment has reduced the spleen, and caused me to be in the present enjoyment of better health than for a long time previous." From Dr. E. E., Factory Point, Vt., April 4, 1837. Mental Derangement, etc—" The credit of your medicine is established here. One of the first cases in which I tried them was a young man in an awful state of mental derangement. He had been in this way for three months—became greatly emaciated, and refused to take any medicine. I recommended the application of your Liniment, which was made with much difficulty, however, and, in three weeks, his mind was as rational as ever. Soon after, sore eruptions took place about his head, and were, in a short time, cured. Another case was a young man who had been con- fined with scrofulous SAvellings for five years, Avho, by the use of 352 TESTIMONIAL. six ounces of your Liniment, Avas much relieved, and is now evi- dently getting Avell." From Dr. J. Steele, Frankford, Mo., May 4, 1837. " I will give you a case of fits cured by your Liniment and Dia- phoretic Drops. A child of two years had, in twenty-four hours, eleven fits of the Avorst kind: they were convulsive. The family had, just before the attack, read your Advertiser for the first time. After the child had suffered a day and a night, I was sent for. I found the child then under the paroxysms of the eleventh fit, and I really believed it to be its last. By a faithful application of your remedies, the child had no more fits, and in tAvo days it Avas Avell. Two Aveeks have elapsed since, without return of the fits." From Rev. William Dale, Alexandria, Tenn., October 19,1837. " Previous to my leaving home, the latter part of August, on a preaching tour of twenty-two days, I made an application of your Rheumatic Liniment on the spine, hips, and knees, beginning at the neck and so on dowmvards, applying it with friction and heat. It produced a powerful effect on the kidneys, and I think Avill re- lieve the diabetes, Avhich I have been troubled with for years. It loosened the joints of the small of my back, which had been en- tirely stiff for years, and I can iioav bend either backAvards or for- wards ; also my knees, which had been as fast and immovable as if clenched, became loosened. When sitting in a position to swing my feet, I can use them as far as they go, nearly as well as I ever could; though my hips are not yet better, my head is much re- lieved. I certainly have gathered considerable strength. I was from home, as above stated, twenty-two days, during which time I traveled more or less every day. I preached ten times in eight days, Avhich is more labor than I ever performed in the same length of time. If I could stay at home a while, attend strictly and closely to your prescriptions, I doubt not I should receive much more benefit. " My wife's sister was taken with a pain in her leftjaw, which FEVER AND AGUE, ETC. 353 SAvelled dreadfully, to obtain relief from which, she tried every thing she could think of, and every thing her physicians prescri- bed ; but, instead of getting better, it got Averse. She felt fearful of applying your Liniment, notwithstanding our advice to that effect. At last she became alarmed; the swelling Avas suppura- ting, and it Avas too late to apply any thing to disperse it; and, as a last resort, she applied your Liniment. The first night, she found ease and rested well, which prompted her to persevere, and, astonishing to relate, the pain first gave way, then the swelling subsided, and she is iioav entirely well. She says ' It Avas almost a miracle.' " The Head-ache Liniment is highly esteemed by all Avho have used it." From Dr. John Hilton, Portland, Maine, October 23, 1837. " After I wrote you in July, I was unable to go from home a number of Aveeks from a severe kidney complaint; but, through a faithful application of your Liniment and other medicines, my health is better than for years. My success in practice has been remarkable. Fevers have generally been arrested Avith one appli- cation of the Liniment, and the patient at work the third day. In some cases, they have Avalked about in six hours. In all diseases, the relief granted has been proportioned to the degree of perseve- rance. I had an interesting case immediately after my arrival here : a child of Elder Wilson, four years old, had been sick, for a Aveek, Avith fever and inflammation of the bowels; had taken four full and one partial course of medicine; but grew worse. Your Liniment was then applied, and relief granted in six or eight hours; then, by throAving off the clothes, the child took cold and relapsed. The fever was more violent, and the bowels worse in- flamed ; but, by a renewed use of the Liniment, Avas relieved again in two days, and was soon running about." From Dr. Richard Cherry, East Monroe, 0., October 29, 1837. " I will not be Avithout your medicine, if I can raise the means to obtain it. It is the best remedy that I have ever tried for every •15 354 TESTIMONIAL. complaint incident to the human race; more particularly for fever and ague, Avhich I have effectually proved." From Dr. A. Eelwards, West Carlisle, O., November 17, 1837. " Were it necessary, I could give more marked cases than would fill your Advertiser; but let one suffice. I was lately call- ed to a lady, sixteen miles from this place, afflicted Avith fever of the congestive type. She had been faithfully attended by a phy- sician near two Aveeks ; the second one was called in consultation, and, finally, I Avas sent for. I immediately Avent, and found her delirious, the fever raging fearfully, Avith great prostration of the living poAver; no appetite for food, but raging thirst, and such a degree of irritation in the stomach that every thing taken into it was immediately throAvn off; constipation of the bowels, great restlessness, and a constant picking at the bed clothes; pulse intermittent. " I applied the Liniments for Fever, Nerves, and the Stimula- ting, according to circumstances, until I had four ounces absorbed into the system, Avith plasters on the stomach, bottoms of the feet, and back, and administered an injection impregnated Avith Diapho- retic Drops, which caused a reaction in about two hours, and pro- duced a copious perspiration which had not been effected before. The result was, she was restored to her reason, the fever gave way, appetite for food returned, Avith a fair prospect of entire re- covery." From the same, December 30. "A Mr. Daniel Harvey, of this county, Avas afflicted with a very alarming disease of the urinary organs, bloody and painful discharge of urine, distention of the abdomen, with a callous-like feeling, liver complaint, piles, and general prostration,—so much so as to be unable to help himself,—attended Avith frequent parox- ysms of excruciating pain; Avhich diseases, in part or whole, had been his constant companions for many by-gone years. In this situation, I was called to see him; and by a constant and unremit- WEAKNESS, ETC. 355 ting application of your medicines, the distention gave Avay, the pain ceased, sleep was restored, appetite better, the urinary organs so revived that he commenced passing large quantities of hard substances of a dark-red color, varying from the size of a pepper- corn, larger and smaller, which gave him relief. At first they were discharged frequently, and in large quantities; latterly more seldom, and in less quantities, Avith less pain and difficulty. I sup- pose he has discharged one hundred, as I have in my possession nearly fifty pieces. When I visited him last, he was able to sleep, rest, and eat, dress himself, Avalk about, and direct his business, with a fair prospect of getting entirely Avell." From Dr. J. B. McCord, Liberty, Clay county, Mo., November 21, 1837. " I have just returned from a visit to Lafayette, a distance of forty miles, Avhere I Avas called to see a lady afflicted with liver complaint and inflammation of the bladder, attended with a severe stricture of the urethra. Three physicians attended her, Avithout being able to afford relief. I directed a free use of your Stimu- lating Liniment, and some Diaphoretic Drops, which reduced the inflammation, removed the stricture, and enabled the patient to enjoy refreshing sleep." From J. Hilton, Portland, Maine, January 8, 1838. "A lady completely emaciated, unable to do any Avork, com- menced the use of the Liniment. The morning after the first ap- plication, she Avas enabled to do part of the work of her family; and now (five Aveeks) she does all her Avork, and has received her natural strength. One case of tic douloureux was relieved by tAvo applications. Many cases of fever have been removed by one application. Several cases of pain have been relieved Avhile in the act of applying the Liniment. Hooping-cough has been re- lieved immediately, though very bad cases. Rheumatism has been cured permanently." 356 TESTIMONIAL. From Samuel H. Saunders, London. Ohio, Jan. 6, 1838. Milk-Siokness.— " It is a duty I OAve the public, to certify the cures that have been effected by your invaluable medicines in my family. Your Liniment had a very happy effect upon my daugh- ter, in a case of pleurisy. I left Avith her a portion for a renewed application; but the first having completely restored her, it Avas deemed unnecessary. While on my Avay home I partook of some cream, and two days after my arrival, I Avas attacked Avith milk-sickness. My physician administered a cathartic, and checked the disease; but for eight or ten Aveeks my legs Avere pained with the effect of the poison, Avhen I determined to make use of your Liniment. I rub- bed it on my limbs tAvice, on successive evenings, but Avas pre- vented from making a third application by incidental circumstan- ces; and before the fourth evening came round, I found myself so relieved from the pain and leaden Aveight of my limbs, that I for- bore to reneAv the use of the Liniment for the time being: and to this day, I Avas effectually relieved, and therefore can Avith confi- dence recommend its use for removing the effects of milk-sick- ness." From Dr. T. Powell, Burlington, Vt., Jan. 17, 1838. " In relation to your remedies, I must say, that so far as I have become acquainted Avith their use, they are undoubtedly calculated for the cure of many diseases." From Rev. E. McDaniel, M. D., Beardstown, Illinois, January 1, 1838. " Every useful and honorable consideration impels me to exert myself for the dissemination of your remedies." From E. Wilkinson, East Bethany, N. Y., Jan. 5, 1838. " I have of late been most of the time confined to my room: I have CONSUMPTION, ETC. 357 found more relief from your medicine, than any other I have made use of. I have cured one case of rheumatism in my family of six years' standing, with your Liniment. "A sister of mine was throAvn from a horse, some ten years ago, her head coming in contact with a stone, Avhich fractured her skull. She has had much burning and giddiness in her head, with great irritation of the nerves. The use of your Liniment has, we think, nearly or quite effected a cure. She has not had any of these symptoms since its use. I think much of your preparations—I hold them in high estimation, believing them to be a safeguard from disease, for a family." From Josiah F. Danforth, Walnut Forest, Mo., Jan. 15, 1838. Head-ache.— "Dr. Walker, of Pulaski county, purchased of me a vial of your Head-ache Liniment, for his wife, who was very distressingly afflicted with head-ache. The doctor says that she Avould lay for hours completely prostrated, Avith apparently no hopes of life. He applied it, and administered some of the Pec- toral Drops, which have effected a radical cure." From B. G. Key, Portersville, Miss., Sept. 9, 1837. " I could give you a detail of a good many cases that have re- ceived signal benefit by your remedies, but let tAvo suffice. "1st, Miss Stanly, Avho had been laboring for the last ten years under a complication of diseases, viz: inflammation of the liver, lungs, and enlargement of the spleen. Her physicians declared that she could survive but a short time, after which she became suddenly worse. When I Avas called to see her, she Avas truly in a critical situation. I prescribed the Fever Liniment, Pectoral Tincture, and Diaphoretic Drops, which subdued the inflamma- tion; then made use of the Stimulating and Consumption Lini- ments, and Vegetable Syrup; which course persevered in, raised her from a bed of affliction to attention to her domestic concerns. She now enjoys good health. " 2d. A negro boy of a Mr. Stamply, Avas in a consumption. 358 TESTIMONIAL. The rest of his family died about the age of tAvelve years, of the same complaint, and this boy appeared to be declining as fast as did the rest of the family; and knowing that it Avas useless to make use of the means Avhich he had heretofore done, I was call- ed, though Avithout any expectation, on the part of Mr. S., of de- riving benefit; but after a partial use of the medicines, he found that the boy began to revive, Avhich encouraged him to persevere. He is iioav lively and active, has regained his flesh, and is entirely cured of the complaint." From Rev. E. McDaniel, M. D., Cass county, Illinois, Sept. 25, 1837. " Last month I procured from my brother, near Paris, a small quantity of your medical preparations. I had been troubled, for about two weeks, Avith a diarrhea; and while attending a camp- meeting at Grandview, it grew Avorse. I used one thimble-full of your Liniment, and soon obtained relief. I next ordered it used in a case of bloody flux, and it effected a good end; I next ordered it used twice in case of chills and fever, and a cure Avas effected: next day my OAvn child Avas affected Avith diarrhea, Avhich I cured by one application." From Dr. A. C. Jewett, Daviess county, Ky., Sept. 25, 1837. " Many are embracing your remedies, and using them Avith marked success. A number of cases of bilious, inflammatory, and intermittent fever, of our climate, have come under my care, Avhich have been arrested with precision and certainty. The Li- niment for Head-ache has established itself beyond any other arti- cle—it never has failed, in any instance, of giving relief." From C. Barnes, Weymouth, Ohio, March 15, 1837. Rheumatism—Consumption.—" More than five years ago I was attacked with inflammatory rheumatism of the severest kind, RHEUMATISM, ETC. 359 in my feet and knees, Avhich kept me in constant pain, day and night, for three months ; deprived me of sleep, except while under the influence of opium, and rendered me so completely helpless, that I was unable to turn myself in bed without assistance. My appearance, after this prostration, was almost that of a living ske- leton. The inflammation then began to subside. In March, I could, by the aid of crutches, and one assistant, walk about my room. I gained strength gradually, until July, Avhen I was able to walk Avithout crutches; but still the disease did not leave me. Though the inflammation Avas gone, the joints Avere stiff; the muscles contracted, and the toes drawn out of joint, particularly on one foot, which was entirely useless. My physicians gave me no further encouragement, and, Avith much candor, told me that no- thing more could be done for me, and that I would probably re- main a cripple. I Avas, however, determined to seek relief. I resorted to the Welsh Medicamentum—the Thompsonian reme- dies—Morrison's Hygeian Pills—E. Dean's Chemical Plaster,— and, finally, the famous Kitterage Ointment; all these modes and medicines, were, in succession, long and faithfully persevered in, each, hom three months to a year. " Some of them seemed to give partial relief at first; but a re- turn of my complaints, Avith still greater force, indicated that their only effect was, to aid the disease in undermining the remnant of constitution still remaining to me. Hope Avas gone, Avhen your Register, containing the words, so encouraging to the afflicted, of " No Cure, No Pay," accidentally fell into my hands. My hopes revived, and I determined on visiting you forthwith ; but suddenly I was attacked with a bilious fever, and then, by fever and ague, which confined me eight weeks ; gave a terrible shock to my sys- tem, and left me with a severe cough. In a short time, profuse evacuations of blood from the lungs took place, attended with other symptoms, evidently of a pulmonary affection. My rheumatic complaints were severe as ever ; and when I arrived in Columbus in November last, I was thought, by all Avho saAV me, to be on the very brink of the grave. " By ten days use of your medicines for cough, consumption and rheumatism, I became so much relieved, that my cough had almost left me; my appetite Avas good, and I was otherAvise so 360 TESTIMONIAL. much improved, that, instead of remaining Avith you nine months or a year, as I had contemplated, I left for home. " I have made constant use of the medicines, and I noAV feel, almost, like a perfectly well man. My cough is gone; I am gaining flesh and strength; the sivelling and stiffness in my limbs are gone ; my appetite Remains good, and my system is re- gular in all respects.'n Remark.—A few days since we received a letter from the writer, of the above article. The state of convalescence he speaks of con- tinued without interruption, and he is, at this time, July 1838, and has been long since, Avithout further occasion for medicine, and is in the enjoyment of good health. Rheumatism.—" Nearly tAvo years ago I was severely attacked Avith rheumatic pains in my back, limbs, feet and hands ; my dis- tress Avas so great that my limbs became nearly useless, and the distress folloAved me, Avithout intermission, for a long time. At length it became periodical, and so continued until sometime in September last I made application of JeAvett's Liniment for Rheu- matism, accompanied with his Diaphoretic Drops, Avhich afforded relief in a short time, and I Avas perfectly cured of the complaint in one Aveek, and so remain at this time. Once, since being cured as above stated, I experienced a slight attack, which Avas immedi- ately relieved by applying the Liniment. I consider this cure more extraordinary, on account of my age, Avhich is sixty-four years. Mary Sterret." Remark.—The signer of the above certificate is the lady of Col. Sterret of this city, who is one of the oldest and most respec- table inhabitants of the State. From James B. 3FCord, M. D., Elkhorn, Ray county, Mo., September 6, 1837. Inflammatory Rheumatism.—"I Avas called to see Mrs. Hard- ley, laboring under bilious inflammatory rheumatism. She Avas BILIOUS INFLAMMATORY RHEUMATISM, ETC. 361 much reduced, the pain appeared to be mostly confined to the wrist and hand, which were much swelled and inflamed, and the pain was very acute. She had exhausted the skill of her physi- cian in vain. I gave her Diaphoretic Drops, and applied the Rheumatic Liniment, her pain ceased, she rested and slept com- fortably at night, and in four days Avas up and about her house." Inflammatory Rheumatism.—Six months ago, I was attacked severely with the inflammatory rheumatism. On the commence- ment of the attack, I was swollen in my arms, knees, ankles, and legs, attended with the most excruciating pain, and so prostrate that I could not be removed from my bed, Avithout the assistance of two persons. By the remedies I applied, I gained some tem- porary relief, but no cure. Nearly tAvo months after, I applied to Col. JeAvett for his remedies for rheumatism, which, in the course of a Aveek, gave me temporary relief. I continued the use of the Rheumatic Liniment, Vegetable Syrup, and Diaphoretic Drops, accompanied with a saline bath, for about two months, Avhen I became entirely restored to health. There still remained some stiffness in my limbs, Avhich has been relieved by an occasional use of the Liniment. I have been subject to this complaint from early life, and seldom obtained any mitigation in a less time than six months, and generally longer. Thomas F. Jones. Columbus, February 8, 1837. From James B. M'Corel, M. D., Ray co., Mo., July 10, 1837. Bilious Inflammatory Rheumatism, Chronic Complaints.— " I feel with many others, free to bear testimony to the efficacy of your invaluable medical preparations. Since I received my last supply I have been thronged with business from all directions. A severe case of bilious inflammatory rheumatism has recently come under my treatment; in fact, so prostrated was the patient, that both physician and friends had entirely despaired of his re- covery ; and he assured me, that to see his house crowded with 46 362 testimonial. his friends, to see him breathe his last, filled his mind with de- spair. At this critical period I arrived; placed bricks to the fire to heat—gave him your Diaphoretic Drops freely, and applied your Liniment for Rheumatism over his Avhole body, and placed the warm bricks around him. This treatment soon caused a pro- fuse perspiration; pains gradually subsided, and a continuation of this treatment for a feAV days, restored him to such a state of health, that he was enabled to start on a journey to Alabama. " A great number of chronic complaints, such as consumption, liver complaint, scrofula, etc., have been cured by your remedies, and many recent diseases have been almost instantaneously reliev- ed. These are stubborn facts, and I will not Avithhold my testi- mony, believing it the duty of every good man to do what lies in his poAver, to promulgate a knoAvledge of the best means of re- lieving the sufferings of human nature." Paralysis.—Col. JeAvett: I hasten to perform a duty I owe to you, in stating the results of my experience in the use of your medical preparations. As it respects my general health, it is much improved, which I ascribe to your Vegetable Syrup and Liniment. I experience little or no pain; there remains a slight constriction of the muscles, which I have no doubt would have been entirely removed, if I had followed your prescriptions to the letter. In more than a dozen cases, your Rheumatic Liniment has granted relief. In one case of twelve years' standing, and another of a child who had lost the use of its limbs. I have felt richly re- Avarded for all the trouble I have had in promulgating a knowledge of your remedies, by the blesssings they have dispensed to the afflicted around me. C. Burnside. Gambier, February 12, 1838. From J. E. Todd, Esq. Carlowsville, Alabama, June 26, 1837. " In my own family, I have generally found your remedies to answer well, the purposes for which they are intended. A phy- sician near me, has been in the use of your Liniments for the last SUNDRY CASES. 363 eight months; he speaks in the most flattering terms of their re- spective merits." From Hugh Quinn, M. D., Missionary Station, Ga., June 16, 1837. Sundry severe cases cured.—" I had made up my mind not to use any of your highly recommended remedies, until I saw the recommendations of two highly respectable gentlemen, Avhich induced me to seek and obtain a four ounce bottle of your Stimu- lating Liniment. I began to use it on myself, and applied it to an old wound in my hand, from an injured cartilage, which rendered the middle of the fore finger useless and painful. It acted like a charm, one application removed the Avhole disease, and it has not returned since, though five months ago. My success in this case, prompted me to make trial on a valuable servant, who had, for a long time, been afflicted Avith a chronic pain in the side, which had baffled all medical aid which had been resorted to, which very shortly gave permanent relief. I have cured another of my ser- vants of a chronic erysipelas, with the same Liniment. Shortly after, I had occasion to put your Liniment to a severe test on my- self, by a fall across the edge of a ferry-boat. I broke the side of my breast-bone, and every rib from that doAvn, and injured the right lobe of my lungs; being more than fifty years of age, I an- ticipated the most disasterous termination. I did not stand still, 'shivering on the brink of death,' but began by using some inter- nal stimulating medicine and balsam of fir, and your Liniment ex- ternally. I soon became convalescent, and am now entirely re- stored to health and strength. Besides this, I have, in several cases, removed the pains so common in chronic hepatitis, and with the addition of my pills for that disease, have performed two radical cures. I have cured two cases of rheumatism, and several other local pains; and all this Avith one bottle of Jewett's Lini- ment. I have thought, sir, it Avas due to you and the public, that I should acknoAvledge the great benefit that myself and others have derived from one bottle; and I do not hesitate to say, that if properly and perseveringly used, incalculable benefit may be de- rived to the human family, by its use. I have lately received an 364 TETSIMONIAL. additional quantity of the Liniment, since which, I have cured a bad case of croup, by the use of it alone." From Jonathan Morris, M. D., TVhitely, Pennsylvania, July 8, 1837. " I have found your preparations advantageous in cases of scar- let fever, colics, rheumatism, head-ache, etc., etc." Head-ache.—Col. M. Jewett: Dear sir—I take pleasure in communicating the following, as the surprising effects of your Head-ache Liniment. I had a slight attack of the head-ache, a few evenings since, from Avhich I Avas relieved by the application of a very small portion of your Liniment to my forehead, in a few minutes. I called this day to see a female friend, who Avas suffering much from head-ache, which she first felt on rising early. I informed her I had derived benefit from the use of your Lini- ment. After an hour's conversation, she consented to apply it according to the direction, which relieved her entirely in about five minutes. She was much surprised at its hasty and happy effects, and expressed a Avish to have some of this preparation always at hand, and inquired Avhere she might procure it. I gave her a part of Avhat I had, promising to furnish her more as soon as I could procure it. I think you would do well to deposit a quantity of your preparations in this city, for they will certainly be used as soon as known. Very respectfully, R. J. Powell, M. D. Washington, January 18, 1837. From Mary Read, Jefferson, Ohio, February 12, 1838. " Having received incalculable benefit from the use of your me- dical preparations, in afflictions on my own person, when every other remedy I could procure had totally failed of giving relief; CONSUMPTION, ETC. 365 and feeling it a duty, so far as in my power, to dispense the bles- sing they afford to the afflicted, I have taken the liberty of narra- ting the surprising effects of your remedies in a case which came under my OAvn observation. It is as follows :—A gentleman, aged sixty-six years, had been afflicted with an erysipelas, more or less, from his youth; and for the last seven years, his Avhole body had become measurably covered with corroding ulcers ; such was his affliction, that he assured me he could seldom, if ever, obtain any sound sleep ; and many times so tender were the sores, that even the bed-clothes could not be borne. He had applied to the most skillful physicians, and continued their prescriptions from year to year, without any mitigation of his excruciating sufferings, and he had despaired of obtaining relief from any other source, than the releasement from suffering and pain that is afforded to the afflicted by the cold embrace of death. It Avas in this critical situation that one of your Advertisers came under his notice, Which induced him to apply to me for your remedies; and, surprising as is the fact, by the exhibition of your Vegetable Syrup, Pectoral and Diapho- retic Drops internally, and your Stimulating Liniment on the sound portions of his body, and your Vegetable Cerate on the ul- cers, for the term of about three weeks, his ulcers became healed, his general health restored, and he is at this time perfectly relieved from all the diseases with which he had been so long afflicted." From the Rev. A. Edwards, West Carlisle, Coshocton county, Ohio, June 17, 1837. Consumption.—"I have two cases of consumption which are in a hopeful state of convalescence. Had it not been for the un- paralleled success I have had with your agents, I should not have attempted these given over cases; but strange as is the fact, I have lost but one patient since I adopted your remedies, nearly two years ago, and that I pronounced hopeless at first sight. It is with heartfelt pleasure I see. your system of curing diseases, con- stantly marching forward with a steady but unerring step ; and so it will continue to proceed, until a knoAvledge of your remedies shall be co-extensive Avith this Avide-spread empire." 366 TESTIMONIAL. From Abraham Hedstead, Esq., TViHiamsport, Ohio, June 20, 1837. " I have full demonstration of the great value of your Liniment. One case of a boy, Avho has recently been raised from an untimely grave by them. I say so, because all other remedies failed, and by the application of your remedies, he soon recovered." From the Rev. E. E. Parrish, Morgan county, Ohio, June 1, 1837. Tetters.—" What I have seen published of your remedies, 1 have found, by their application, to be true. Permit me to men- tion one case, of which I do not recollect of having read one simi- lar in your paper. A gentleman called on me for something to cure a tetter on his wife's hand. I gave him twenty-five cents worth of your Tetter Salve, which Avas applied; and the result was, that it effected an entire cure. Her hand had been very bad, so much so, that she could not attend to the common avocations of her house. I have since called on her, and find the hand still well. I have seen great benefit from your fever remedies among children." From Van V. Reeves, Esq., Harelin county, Ohio, July 17, 1837. Sick Head-ache.—" When traveling through Columbus, in April last, I called at your store to procure some Head-ache Lini- ment for my Avife, Avho has been afflicted with the sick head-ache from her childhood. The next day after our arrival at this place, she Avas severely attacked. She applied your Liniment as direct- ed, and she got relief on the first application. She had no more for six weeks, Avhen a slight attack occurred, Avhich was instantly relieved by an application of the Liniment. I consider this cure the more extraordinary, as she has frequently been confined for a week at a time. I send this communication for no other purpose than bearing my testimony to the unequalled virtue of this remedy." CONSUMPTION, ETC. 367 From Solomon Allen, Snow Camp, North Carolina, 6th month 27, 1837. " Thy medicine only need be known, to be appreciated by the whole community. I have cured some chronic complaints, after all other means had failed. Some Avonders have been performed by thy medicine. A girl of thirteen years old was suddenly at- tacked with a difficulty of breathing, and continued on her contin- ually, only when she slept. She had paroxysms three or four times a day, Avhich indicated sudden dissolution ; and at the most easy times, she would constantly throAV herself into different atti- tudes at every breath. Some of the symptoms were those similar to the diseases of the heart. The most able physicians afforded her no relief. Some Aveeks after I was sent for, and applied thy Liniments, Avith some internal medicine, and she Avas directly re- lieved, and has not had a paroxysm since." From John Turner, Fountain Springs, Tennessee, June 5,1837. " I have used your Liniments and other remedies in my prac- tice, for tAvo years, and I find them indispensible to full success. For in no one instance, during that period, have I lost a patient, when your preparations were administered. During the above period, I have successfully treated cases of consumption, rheuma- tism, colic, female diseases of every type, dyspepsia, liver com- plaints, pleurisy, congestive fevers, bilious and typhus fevers, some of Avhich, to all appearance, Avere near the agonies of death, before I saAV them, and I have been uniformly successful. In one of the most severe cases, I found it necessary to keep the patient in a profuse perspiration with your remedies for four days, through which means the disease was conquered, and the patient reco- vered." From B. G. Key, Portersville, Mississippi, August 6, 1837. " A lady, who has been under my treatment with your reme- dies, has nearly recovered of a confirmed consumption; and ano- teer has been cured of an enlarged spleen, inflammation of the liver and lungs, bordering on consumption." 368 TESTIMONIAL. From J. Hilton, Deerficld, N. H., July 7, 1837. " Your medicines equal all that has been said of them in your Advertiser. I knoAV of a case of sick head-ache, of more than tAventy years' standing, that Avas cured by your 11 cad-ache Lini- ment in a very feAV minutes. Never before had the patient found any remedy that Avould afford relief. Had I leisure, I Avould enu- merate many remarkable cures." Case of Consumption and Fluor Albus.—C. D., a lady of much respectability, had been afflicted Avith the above complaints for nearly seven years ; pain in the left side and shoulder blades ; severe cough, expectorated daily large quantities of pus streaked with blood ; head-ache ; nerves much affected ; bowels irregular; SAvelled ankles; and continually distressed Avith wandering pains. After applying a variety of remedies Avithout gaining any perma- nent benefit, she applied to us for medicine about four months ago, and, at this time, she appears to be entirely relieved of all her com- plaints ; in less than three months, her cough was cured—her sys- tem, generally, has become regular. We consider this case more extraordinary from the fact that it has required much less medi- cine to effect a cure than in cases generally where the patients have been similarly afflicted. We have noticed this, and the pre- ceding cases, among a vast number which we have knowledge of, for no other purpose than to turn the attention of those similarly afflicted to the means for relief, which have uniformly been suc- cessful Avhere a persevering treatment has been pursued. It is with much difficulty Ave can present to the public a full statement of these delicate cases of affliction, and the vast number of ladies, of the first respectability, who have been relieved by our remedies, and have promulgated the fact among their neighbors. From Rev. A. Edwards, West Carlisle, Coshocton county, Ohio, February 23, 1838. Fits.—" I have recently cured a case of fits, with your remedies, DYSPEPSIA, ETC. 369 in a case of a child four weeks old. When I first visited the child, it Avas struggling in a severe paroxysm, to all appearance, in the agonies of death; I applied the Nerve Liniment to the stomach, abdomen, spine, and bottoms of the feet; gave the pectoral tinc- ture once in fifteen or tAvent)j minutes, according to the symptoms, and, in a feAV hours, the child Avas entirely relieved, and continues so at this time." Remark.—In cases of fits, Ave Avould recommend the child to be immersed in warm Avater at first, wipe dry, and then apply the remedies as above mentioned. From the same, March 16. Tic Douloureux.—" I Avas recently called to visit a young gen- tleman laboring under a neuralgic affection, and general prostra- tion ; had been treated, in the usual method, by some of the most skillful physicians, for several weeks, Avithout relief—all hopes of recovery were given up by his medical attendants and friends. At this inauspicious period, I was called ; I ordered your Nerve Lini- ment applied liberally with Avarmth and friction, the Diaphoretic Drops taken with a cathartic. The result of this course Avas, that his pains soon subsiding, a state of convalescence ensued ; and, by a few applications of the Liniment, he Avas restored to entire health in a feAV days, and noAV remains a living witness of the efficacy of your invaluable remedies to this day. Dyspepsia and Liver Complaint.—"I Avas called to visit a lady, near Gambier„Avho had been laboring under the dyspepsia and liver complaint for more than a year ; a short time before, she had been delivered of three children at one birth, which caused a local uterine imbecility, Avith deranged menstruation and general debility. I prescribed for her, and, by a prompt and constant ap- plication of your remedies for a feAV weeks, she was relieved from all her complaints to the astonishment of all who saw her. Dyspepsia.—" David Morris, of this county, had been laboring under the dyspepsia, for a number of years, in its Avorst and most distressing forms ; he had despaired of ever gaining relief, as all 47 370 TESTIMONIAL. the means he had resorted to had entirely failed. A ray of hope beamed on his countenance after my first application of your reme- dies. I furnished him with your remedies usually applied in such cases, and, in five or six Aveeks, his bowels became regular, his food set well on his stomach, his strength Avas restored, and he as- sured me that he Avas able to perform as much labor as Avhen he was a young man in sound health. He is a grateful living monu- ment of the efficacy of your remedies in dyspepsia, and he pro- claims abroad that almost a miracle has been Avrought upon him He has been the means of directing five or six similar cases to ine, Avho have all found relief by applying the same means. Tertian Ague, Distention of the Spleen, etc—" George Lydeck, near West Bedford, in this county, had, for a long time, been afflicted Avith the tertian ague, chronic derangement of the di- gestive apparatus and boAvels, distention of the spleen, and general debility, Avas mostly confined to his bed for fourteen Aveeks ; he had been attended by tAvo of the best physicians, but of no avail. I Avas called, and commenced the exhibition of your Diaphoretic and Alterative Drops, applying the Liniment and my cathartic pills. This course at once gave relief, and, by a feAV weeks' ap- plication, he has been restored to entire health. Severe Contusion of the Hand.—" A young man, near War- saw, had three of his fore-fingers torn nearly off in a threshing ma- chine—bones fractured. When I Avas first called, his hand had been dressed by a physician; but he remained Avith much pain. I took off the splints and bandage, and found the Avound approach- ing to mortification. 1 Avas compelled to amputate one of his fin- gers. I then washed the Avound Avith the Diaphoretic Drops, and bound it up with the Vegetable Cerate. This course arrested the mortification, and, in a feAV days, entirely cured the Avound. " Thus I have given you a few out of a vast number of cases Avhich have come under my treatment Avith your remedies. I have no other object than to disseminate a knoAvledge of the fact that your remedies actually reach the worst forms of disease Avith more readiness, more certainty, and Avith less expense, than any other Avithin my knoAvledge. AGUE, ETC. 371 From Dr. J. Biles, Fort Jefferson, Ohio, March 12, 1838. " I am not as yet acquainted Avith every variety of your reme- dies; but your Liniments for Rheumatism, Head-ache, BoAvel Complaint, etc.; Pile and Tetter Salves; and your Diaphoretic and Pectoral Tinctures, I have used in my practice for some time past, and I do assure you I hold them in high esteem; not an in- stance do I recollect of ever prescribing either of the above medi- cines, Avithout the most prompt and salutary effect. I Avould be glad to have forwarded a number of your Advertisers, for circula- tion, as it is my Avish (as I have partly declined practice) to have a knowledge of your valuable medicine thoroughly throughout our section of the country, in order that their use may become general as a family medicine, for Avhich purpose they are so Avisely adapt- ed." From Samuel H. Saunders, Esq., Springfield, Ohio, March 26, 1838. " The bottle of Head-ache Liniment I purchased of you Avhen last in Columbus, for Mrs. General Bond, of London, Avas applied a few days afterAvards, Avith her first paroxysm of nervous head- ache after she got it from me. I saw General Bond three months after, and of his OAvn accord, his face beaming with joy, he re- marked to me, that 'Jewett's Liniment for Head-ache cured his ivife of her long-continued and severe paroxysm of that disor- der, and at one application; because (said he) it has never re- turned upon her since.' " From Rev. E. McDaniel, M. D., Beardstown, Illinois, March 28, 1838. "As to your chimical remedies, I knoAV not how to speak their Avorth. I am better pleased Avith their certainty of effect, and promptness of action, than any of my previous acquaintance. The most prominent forms of disease, successfully treated under my observation, have been, quotidian and tertian ague, bilious inflam- 372 TESTIMONIAL. matory rheumatism, lumbago, hysteritis, amenorrhea, sick head- ache, cholera morbus, and pleurisy—all of Avhich have yielded readily to your remedies. I am happy to knoAV that that confi- dence to Avhich your remedies are entitled, is spreading far and Avide. Such are the effects produced, that a little time will esta- blish them, through the far West, as a family medicine." From Dr. E. C. Keckeley, Charleston, S. C, April 1, 1838. " Your preparations, I am pleased to say, are gaining a firm foundation. I cannot do Avithout them in my practice—they are so safe, so simple, and so certain of overcoming the diseases for Avhich they are designed. I have succeeded lately in curing a case of paralysis in one side of the body, in an old Avoman, Avith three ounces of your Stimulating Liniment. I have known tAvo or three cases of incipient consumption cured by a small quantity of your Consumption Liniment. Your Pile Salve cures every case. I have not failed in one instance. I cannot be more expli- cit—but one thing is certain, that with all that has been published, your remedies have not been sufficiently highly recommended." From Rev. A. Edwards, March 20, 1838. "As I promised I Avould give you more marked cases for publi- cation, I have come to the conclusion that it is my bounden duty to 'render unto Cesar the things that are Cesar's.' " Scrofula.—Some time the last spring, I Avas called to see a child in this village, about five or six years old, laboring under scrofula. He had indolent tumors Avhich had seriously affected one of the conglobate glands, near the size of a hen's egg, mova- ble under the skin, Avithout pain or discoloration; the circulating fluids had become very much corrupted, with general cutaneous eruptions. Many means had been resorted to for relief, Avithout benefit. When I Avas called, I commenced an application o. tl e Stimulating Liniment over the surface of the body, and gave the Alterative Drops, occasionally applying the saline Avash. The re- TYPHUS FEVER, ETC. 373 suit was truly astonishing; for in two or three Aveeks the boy Avas cured, and remains well at this time, Avhich has been nearly one year. " St. Vitus' Dance.—A young lady of this place had been laboring under the above complaint for a long time. Several phy- sicians have treated the case without success. The disease con- tinued to rage; her appearance was truly frightful. After I Avas called, I applied your remedies for that complaint, accompanied Avith my pills as an alterative, and gave her valerian tea, and ap- plied the saline bath; and in less than two months she Avas entire- ly cured, and so remains to this day, nearly a year after the cure Avas effected. " Typhus Syncopalis Fever.—I Avas called to see a girl, a feAV miles from this village, laboring under some indisposition of fever; and Avhen on my last visit to her, after her convalescence, her brother Avas attacked Avith the above disease. It Avas distin- guished by sudden and great debility, from the first attack, Avhich prostrated the system at once, without any appearance of reaction; extremities cold, and the skin entirely insensible to the most poAV- erful rubefacients; a sense of fainting at the stomach; pain in the epigastrium and head; then vertigo, and delirium. I commenced the treatment by a liberal application of the Liniment and Diapho- retic Drops, and my pills as a cathartic. At first, I failed to pro- duce a perspiration, or a passage from the bowels; I then gave one drop of croton oil, which had the desired effect: I then ordered the saline bath, made strong by high-Avines and vinegar, and then folloAved up Avith the Liniment and strong mustard poultices to the wrists and bottoms of the feet—it now being nearly forty-eight hours from the first attack, without one hour's relief from the dreadful rage of delirium and obstructed perspiration. But the bath and Diaphoretic Drops acted poAverfully in removing the de- lirium and producing perspiration, which seemed to relieve him of all his disease, except a pressure of phlegm at the stomach, which I endeavored to remove by the Pectoral Tincture emetic, but I feared he Avould sink under the operation; I then applied the Li- niment freely to his stomach, Avhich had the most happy effect; I then gave him two pills, which had the appearance of removing the remains of disease. His strength Avas so exhausted, that I 374 TESTIMONIAL. gave him port wine, loaf sugar, and nutmeg, Avhich appeared to strengthen him much, and in a short time he Avas entirely restored to health, as a living monument of the superiority of the chimical remedies and medical compounds. "Prolapsus Uteri.—I Avas recently called to treat a case of the above disease. It Avas one of the worst cases that has come under my observation. The abdomen was distended, the uterus collapsed, and the Avhole system much prostrated, together Avith the most excruciating pain, attended Avith alarming symptoms of inflammation. I made the ordinary prescriptions for such diseases, but Avithout effect. I then applied the saline vapor—and to the uterus, through the medium of the vagina, a decoction of an as- tringent and slightly stimulating character—and I applied to the intestinal canal, through the rectum, a decoction highly impreg- nated Avith the Diaphoretic Drops, and at the same time ordered the abdomen to be fully rubbed Avith the Liniment, and a large plaster applied to the same, and in a short time she became con- valescent, and a few days more restored her to good health." From the same. Hydrocardia, Dropsy of the Heart—Dropsy of the Per- icardium.—" I have been called to visit some four or five cases of the above complaint during the Avinter and spring, and been suc- cessful in every case, Avhen timely called. In all the cases Avhere there Avas but an inconsiderable accumulation of water in the peri- cardium, I have found no difficulty in overcoming it by the use of your remedies; and all the most forbidding cases where I have succeeded, I have used, in addition to your remedies, my altera- tive pills ; a strong tea of valerian and the saline vapor, all with the happiest effects. This vapor may be produced by putting a small quantity of salt into alcohol, in a cup, and set on fire under a chair, on Avhich sits the patient, covered with a blanket only— at the time of this application, the Diaphoretic Drops may be ad- ministered, and other Avarming teas. The patient will perspire freely, without danger of being faint. I consider this bath a pow- PARALYSIS, ETC. 375 erful auxiliary to your remedies, It is simple and perfectly safe. It acts on the nerves as a relaxant, and on the system generally as a tonic." Remark.'—The dropsy of the heart is a collection of fluids in the pericardium, Avhich may be either coagulable lymph, serum, or puriform fluid. It produces symptoms similar to those of hy- drothorax, Avith violent palpitations of the heart, and mostly an in- termittent pulse. The most skillful physicians have pronounced it incurable. From Perrine fy Gould, Mobile, Alabama, April 12, 1838. Rheumatism.—" Dr. Davis speaks highly of your remedies, and says he could produce hundreds of testimonials of cures per- formed by your medicine. For ourselves, we are happy to be a witness to the many surprising cures performed by your Rheumat- ic Liniment. In fact, it is generally spoken of in terms of the highest praise. No doubt the other preparations will be equally popular Avhen they become as well known." From Mrs. C. Burnside, Gambler, Ohio, May 20, 1838. Paralysis.—" In August, 1835, I Avas attacked with a paralytic affection, that immediately rendered me helpless, and settled in the left side, from head to foot. It required'three persons to lift me up in bed, and for three months I Avas entirely unable to move in bed without assistance. My physician mistook the complaint for rheumatism. After a long time, hoAvever, I mended slowly, and was able to Avalk ; but Avhen I commenced the use of your re- medies, I could not lift my hand to my head, or cut my own food. I had not strength in my arms to break even a thread, Avithout in- convenience. I was drawn doAvn on one side quite out of shape, Avhen I first tvas so fortunate as to procure a vial of your Liniment, the application of Avhich soon afforded me so much relief, that I Avas enabled to make a journey to Columbus, to visit you. The journey, and the remedies I procured and administered, have been the means of restoring me to better health than I haAre enjoyed for 376 TESTIMONIAL. years, as I have for a long time been afflicted Avith a complication of diseases. I am iioav fifty-five years of age, rejoicing in the bles- sings of comfortable health, for Avhich I am indebted, under a kind Providence, to the application of your remedies." From Lawrence Wade, Jefferson county, Mississippi, June 17, 1838. Diarrhea, etc. etc—" To promote the sum of human happi- ness, and to relieve the afflicted, by all the means in our poAver, is a duty incumbent upon every good citizen, and constitutes my only object in giving you a relation of the folloAving facts for pub- lication, in such a manner as you may deem best calculated to pro- mote the desired object. "On or about the last of February, 1837, one of my sons, a child noAV three years of age, Avas attacked with whooping cough, with Avhich it suffered severely for about six Aveeks, Avhen it Avas violently affected Avith the bowel complaint, Avhich continued un- til September last, under all the various types and forms of that disease ; and Avhich had reduced it to a mere skeleton. During that time I had several physicians of acknoAvledged skill to attend the child, all of Avhom pronounced it past the poAver of medicine even to relieve, much less to cure. They all agreed that the lungs of the child had become diseased Avith Avhat they termed pneumo- monia, or inflammation of those organs. I am satisfied that they Avere right as to the nature of the disease, but to describe fully its hopeless situation and sufferings, is totally beyond my poAvers to do Avith a pen; suffice to say, that the child Avas conveyed in a carriage, (but Avith the greatest difficulty,) tAvelve miles, to Mr. Darden's house, and where, by the solicitation of Mrs. Darden, a trial was to be made by Dr. B. G. Key, Avith your Liniments, Pectoral Tincture, etc. The child suffered from the effects of ca- lomel by salivation also, and it Avas the opinion of most persons, and expressed by one of its physicians, that it never could be re- turned home alive. For myself, I had no expectation of its reco- very, and suffered an application of the Liniments only to gratify others; for I confess, my feelings Avere very much opposed to what I then considered an experiment. DIARRHEA, ETC. 377 " I have only to say that no other medicine but your prepara- tions were made use of, and that, to my great surprise, as well as inexpressible gratification, the child is restored to perfect health and soundness ; its flesh has come upon it, in very deed, ' like a child's,' and in all respects appears as though it never had been sick. It will be recollected also, that It was in September last, the very season of the year when disease is very fatal in this country, that Dr. Key commenced, in the foregoing case, the use of your Liniments. The Stimulating Liniment was rubbed over the Avhole body and limbs, and a buckskin plaster of the same, in form of a vest, covering the Avhole chest, constantly worn ; once in two days washing off clean with soap and water, wiping dry, then applying the salt bath, and immediately applying the big plas- ter again, well covered with Liniment. The child Avas first vomit- ed with Pectoral Tincture, which caused it,to throw immense quantities of phlegm from the stomach, and afterAvards the use of the Pectoral, combined with the Diaphoretic Drops, was continued, by giving every two hours, of the mixture, from six to ten drops, diluted in water; and at times, when required to vomit, which was not often, from fifteen to twenty drops of the Pectoral Tinc- ture, diluted in water; and lastly, the Vegetable Syrup was given freely." From J. A. Fairchild, near Raymond, Hinds county, Missis- sippi, June 21, 1838. Diarrhea and Fever.—" Sir: In the month of June, 1835, I first became satisfied of the poAver possessed by your medicines for the removal of disease. Tavo of my black men, at that time, Avere very sick; one of them was so reduced by diarrhea, which had baffled every effort of skill or medicine to relieve for six Aveeks, that I had given up all expectation of his recovery—he Avas, in truth, a hapless being; could neither stand or Avalk, and his digestive organs Avere so impaired, and his whole system so deranged, that even the most simple gruels or soups of any kind, taken into the stomach, would pass his bowels, in a feAV minutes, in nearly its original state. He then got past taking food or me- dicine of any kind, internally, and his A'oice had sunk so low (as 48 378 TESTIAIONIAL. in a case of cholera) as scarcely to be heard. As a last resort, and surely with but little hopes, I applied your Stimulating Lini- ment over the Avhole surface of the body, and continued rubbing it in for tAvo hours; his discharges stopped upon him as soon as I had got it applied over the Avhole chest, and he immediately gain- ed strength. The same application was made the next day, Avhen he was able to walk, and, in three days, he Avas so far recovered as to commence labor moderately of his own accord, and with a good appetite for any kind of food ; and he has remained in good health ever since. " The other man Avas confined with a very high fever : his pains in the back and head Avere most excruciating. I applied the Sti- mulating Liniment over the whole body, (for I could not obtain any of the Fever Liniment,) and, in the course of tAvo hours, he Avas free from all pain, and in a full perspiration; he got well im- mediately. " In neither of the foregoing cases was any other medicine made use of after commencing with the Liniment, nor was there any given internally. " To state all the cases cured by your remedies, within my knoAvledge, even of diseases of the most dangerous kind, would require so lengthy a communication as to be tedious to your read- ers. Suffice, therefore, to say that, since the use of your Lini- ment in 1835, my own family, white and black, has numbered about eighty persons of all ages, and there has not been a single death among them all, except only one black Avoman, who died in child birth. " You Avill please make use of this letter in such Avay and man- ner as you may deem best calculated to convey the knowledge of your most useful medicines to the whole human family, if possible." From Dr. William Armstrong, Philadelphia, April 25, 1838. Insanity.—" I have just received a small lot of your medicine, and, so far as I have tested them, they fully answer my expecta- tions. Some of my most severe cases of chronic complaints are mending under their influence. From what I have already dis- covered, I am confident your remedies will soon go into general INSANITY, ETC. 379 use in this city. Your Head-ache Liniment far exceeds any re- medy I ever knew. There are cases here that have been cured immediately. I have been using your remedies on a maniac taken from the Lunatic Asylum and brought to my house. We kept her one week, and she appeared much better; but she was so troublesome I could not keep her longer. The medicines are to be continued on her after she returns to the Asylum." From the same, May 14, 1838. " I can do more business with your remedies, and approach the bed-side of the sick with more confidence, than I ever did before I became acquainted with them. I consider your medicine to be a great blessing to mankind, and my confidence grows stronger as every case confirms me of the virtues and powers it possesses in the sudden removal of disease. It has been repeatedly asked why there were no great cases, as published in the Advertiser, in this city—the cases being so far off, they cannot see the individual who was cured, or they would try the medicine. Now, to obvi- ate this difficulty, I will give you a living witness in Philadelphia that cannot be doubted ; if it should, Avith the strong proof I have in my possession, they will doubt though one should rise from the dead: Mr. G. T. was laboring under a severe and low typhus fever—not expected to live from one hour to another ; and, with this, an inflammation in the liver, great pain and prostration, and a cough which greatly distressed him. Such was the situation of this gentleman. We utterly despaired of his life. His wife, who waited on him as an attentive Avoman should do in such dis- tressing cases, has the satisfaction of seeing him restored to entire health by a persevering use of your remedies. I gave no other medicine ; but applied your Liniments faithfully over most of the body until a reaction took place. I shall never forget the gentle- man's remark when applying it, as the relief was so instantaneous ; when applying it over the region of the liver, he observed it acted like a charm. At one time, when perfectly delirious, we bathed his feet in a strong solution of salt and water, and then the Lini- ment, and, in a short time, equilibrium took place; he soon gained 3S0 TESTIMONIAL. his right mind, and became convalescent, and is noAV in health again. " Another case of much interest came under my observation: a lady Avho called on me to prescribe for her in case of a Aven, so called by some very learned medical gentlemen Avho Avere then in attendance on her. The physician advised a flax-seed poultice to cause suppuration. It Avas finally determined that it Avas not a Aven, but a Avhite SAvelling. She was attended, by three gentle- men, three years, and, Avith your remedies, I cured her in three Aveeks ; and she noAV lives—yes, she lives, as a monument of an almost miraculous cure, to be seen by the gentlemen and ladies of this city. " I have recently cured a most distressing case of inflammatory rheumatism by your remedies. " The maniac staid Avith us one week only—she Avas much bet- ter, and continued so Avhile using your medicine; but, after she returned to the Asylum, she Avould not take any of the medi- cine, nor suffer any of the Liniment to be applied, assigning as a reason, ' My doctor is not here? We expect to have her back again soon. The higher classes of society in this city, who have used your remedies, approve of them as preferable to any and all others, and you may be assured that, with them, they will gene- rally find favor." From the same, May 26. " The maniac has returned, and is with me, and is evidently bet- ter. If I cure her, it will be the greatest miracle ever performed in this or any other country. Her case is a very noted one. I took her from the Friends' Lunatic Asylum, a famous place for lunatics, about six miles from Philadelphia." From the same, July 3. " I have asked for no testimonials in the cases which have been cured by your remedies—an abundance can be found at any time. I can, as before, state that I view them as excellent. Rheumatism, INSANITY. 381 head-ache, dyspepsia, fever, swellings, etc., are easily overcome by them. "In the case of the maniac, I have entirely depended on your remedies, and, to my utter astonishment, she is nearly herself again. Yes, strange as is the fact, she is now visiting her friends in the city; she appears perfectly rational, and is visiting at her sister's, blending in society, and taking an interest in the common avocation of friends." JCT* Since our letter of July 3, we have a communication from Dr. Armstrong, with the assurance that the maniac is entirely re- stored to her health and to her right reason, and that she is now enjoying the society of her friends in Philadelphia. PART III. PHYSIOLOGICAL. MECHANISM OF THE HUMAN SKELETON. There is scarcely a part of the animal body, or an action which it performs, or an incident that can befal it, or a piece of profes- sional assistance Avhich can be given to it, that does not furnish illustration of some truth of natural philosophy; but we shall here only touch upon as many particulars as will make the un- derstanding of others easy. The cranium or skull, is an instance of the arched form, an- swering the purposes of giving strength. The brain, in its na- ture, is so tender, or susceptible of injury, that slight local press- ure disturbs its action. Hence, a solid covering, like the skull, was required, with those parts made stronger and thicker, which are most exposed to injury. An architectural dome is constructed to resist one kind of force only, always acting in one direction, namely, gravity; and therefore its strength increases regularly to- wards the bottom, when the weight and horizontal thrust of the whole are to be resisted; but the tenacity of the substance is many times more than sufficient to resist gravity, and therefore aids the form to resist forces of other kinds, operating in all directions. When we reflect on the strength displayed by the arched film of an egg shell, we need not Avonder at the severity of blows the cranium can withstand. 381 PHYSIOLOGICAL. Through early childhood, the cranium remains, to a certain degree, yielding and elastic; and the falls and bloAvs so frequent during the lessons of Avalking, etc., are borne Avith impunity. The mature skull consists of two layers, or tallies, Avith a soft diploe between them; the outer table being very tough, Avith its parts dovetailed into each, as tough Avood would be by human artificers, Avhile the inner table is harder, and more brittle, (hence called vitreous,) with its edges merely lying in contact, because its brit- tleness Avould render dovetailing useless. A very severe partial blow on the skull, generally fractures and depresses the part, as a pistol bullet Avould; Avhile one less severe, but Avith more extend- ed contact, being sloAvly resisted by the arched form, often injures the skull, by Avhat is correspondent to the horizontal thrust, in a bridge, and causes a crack at a distance from the place struck, generally half Avay round to the opposite side. Sometimes in a fall, Avith the head foremost, the skull Avould escape injury, but for the body, which falls on it, pressing the end of the spine against its base. In the loaver jaw, we have to remark the greater mechanical advantage, or lever power, Avith which the muscles act, than in most other parts of animals. The temporal and masseter muscles, pull almost directly at right angles to the line of the jaw, while in most other cases, as in that of the deltoid muscle lifting the arm, the muscles act very obliquely, and Avith power diminished in proportion to the obliquity. An object placed between the back teeth, is compressed Avith the whole direct poAver of the strong muscles of the jaw: hence the hnman jaw can crush a body which offers great resistance; and the jaws of the lion, tiger, shark, crocadile, etc., are stronger still. The teeth rank high among those parts of the animal body, Avhich appear almost as if they were severally the fruits of distinct miraculous agencies, so diffi- cult is it to suppose a few simple laws of life, capable of producing the variety of form so beautifully adapted to purposes Avhich they exhibit. They constitute an extraordinary set of chissels and wedges, so arranged as to be most efficient for cutting and tearing the food, and, with their exterior enamel, so hard, that, in early states of society, teeth were made to ansAver many purposes, for Avhich steel is noAV used. It seems, however, as if the laws of MECHANISM OF THE HUMAN SKELETON. 385 life, astonishing as they are, had still been inadequate to cause teeth, cased in their hard enamel, to groAv as the softer bones groAv; and hence has arisen a provision more extraordinary still. A set of small teeth appear soon after birth, and serve the child, until six or seven years of age: these then fall out, and are replaced by larger ones, which endure for life; the number being complet- ed only Avhen the man or Avoman is full groAvn, by four teeth, called wisdom teeth, because they come so late, which rise to fill up the then spacious jaw. The spine, or back bone, has in its structure, as much of beau- tiful and varied mechanism, as any single part of our Avonderful frame. It is the central pillar of support, or great connecting chain of all the other parts; and it has, at the same time, the of- fice of containing within itself, and of protecting from external injury, a prolongation of the brain, called the spinal marroav, more important to animal life, than the greater part of the brain itself. We shall see the spine uniting the apparent incompatabili- ties of great elasticity, great flexibility in all directions, and great strength, both to support a load, and to defend its important con- tents. Elasticity.—The head may be said to rest on the elastic co- lumn of the spine, as the body of a carriage rests upon its springs. Between each two of the twenty-four vertebra?, or distinct bones, of Avhich the spine consists, there is a soft elastic intervertebral substance, about half as bulky as a vertebra, yielding readily to any sudden jar; and the spine, moreover, is waved, or bent a lit- tle, like an italic /, as seen Avhen it is viewed sideAvays; and for this reason also, it yields to any sudden pressure, operating from either end. The bending might seem a defect in a column intend- ed to support weight; but the disposition of the muscles around is such, as to leave all the elasticity of the bend, and a roomy tho- rax, without any diminution of strength. Flexibility.—The spine may be compared to a chain, because it consists of twenty-four distinct pieces, joined by smooth rub- bing surfaces, so as to alloAV of motion in all directions; and a little motion, comparatively, between each two adjoining pieces, becomes a great extent of motion in the Avhole line. The articu- 19 386 PHYSIOLOGICAL. lating surfaces are so many, and so exactly fitted to each other. and are connected by such number and strength of ligaments, lhat the combination of pieces is really a stronger column, than a sin- gle bone of the same size would be. The strength of the spine, as a whole, as shown in a man's easily carrying upon his head, a Aveight heavier than himself, Avhile each separate vertebra is a strong irregular ring, or double arch, surrounding the spinal mar- row. The spine increases in size tOAvards the bottom, in the justest proportion, as it has the more Aveight to bear. The ribs.—Attached to twelve vertebra;, in the middle of the back, are the ribs, or bony stretchers of the cavity of the chest, con- stituting a structure Avhich solves, in the most perfect manner, the difficult mechanical problem of making a cavity, Avith solid exte- rior, Avhich shall yet be capable of dilating and contracting itself. Each pair of corresponding ribs may be considered as forming a hoop, which hangs obliquely down from the place of attachment behind; and so that, when the forepart of all the hoop is lifted by the muscles, the cavity of the chest is enlarged. We have to remark the double connection of the rib behind, first to the bodies of two adjoining vertebrae, and then to a process or projection from the loAver, thus effecting a" very steady joint, and yet leaving the necessary freedom of motion; and Ave see the forepart of the rib to be of flexible cartilage, which alloAvs the degree of motion required there, Avithout the complexity of a joint, and admirably guards, by its elasticity, against the effect of sud- den bloAvs or shocks. The muscles, Avhich have their origin on the ribs, and their insertion into the bones of the arm, afford us an example of action and reaction, being equal and contrary. When the ribs are fixed, these muscles move the arm; and when the arm is fixed, by resting on a chair, or other object, they move the ribs. This is seen in fits of asthma and dyspnoea. The shoulder-joint is remarkable for combining great extent of motion Avith great strength. The round head of the shoulder-bone rests upon ashalloAV cavity in the shoulder-blade, that it may turn in always; and the danger of dislocation from this shallowness is guarded against by tAvo strong, bony projections, above and be- hind. To increase the range of motion to the greatest possible degree, the hone called the shoulder-blade, which contains the MECHANISM OF THE HUMAN SKELETON. 387 socket of the arm, slides about itself upon the convex exterior of thejchest, having its motion limited only by a connection through the collar-bone, or clavicle, Avith the sternum. The scapula, or blade-bone, is extraordinary, as an illustration of the mechanical rules for combining lightness Avith strength. It has the strength of the arch, from being a little concave, and its substance is chiefly collected in its borders and spines, Avith thin plates betAveen, as the strength of a Avheel is collected in its rim and spokes, and nave. The bones of the arm, considered as levers, have the mus- cles Avhich move them, attached very near to the fulcra, and very obliquely ; so that, from working through a short distance, com- paratively, Avith the resistance overcome at the extremities, the muscles require to be of great strength. It has been calculated, that the muscles of the shoulder-joint, in the exertion of lifting a man upon the hand, pull Avith a force of two thousand pounds. The os humeri, or bone of the upper arm, is not perfectly cylin- drical ; but, like most of the other bones which are called cylin- drical, it has ridges to give strength. The elbow-joint is a correct hinge, and so strongly secured, that it is rarely dislocated without fracture. The fore-arm consists of tAvo bones, Avith a strong membrane betAveen them. Its great breadth, from this structure, affords abundant space for the origin of the many muscles that go to move the hand and fingers; and the very peculiar mode of connection of the tAvo bones, give man that most useful faculty of turning the hand round, into what are called the positions of pronation and supination, exemplified in the action of tAvisting, or of turning a gimblet. The avrist.—The many small bones forming this, have a sig- nal effect of deadening, in regard to the parts above, the shocks or bloAVS Avhich the hand receives. The annular ligament is a strong band, passing round the joints, and keeping all the tendons which pass from the muscles above to the fingers, close to the joint. It ansAvers the purpose of so many fixed pulleys, for directing the tendons: Avithout it they Avould all, on action, start out like bow- strings, producing deformity and Aveakness. The human hand is so admirable, from its numerous mechanical and sensitive capabilities, that an opinion at one time commonly prevailed, that man's superior 388 PHYSIOLOGICAL. reason depended on his possessing such an instructor and such a servant. Noav, although reason, Avith hoofs instead of fingers, could never have raised man much above the brutes, and probably could not have secured the continued existence of the species, still the hand is no more than a fit instrument of the god-like mind Avhich directs it. The pelvis, or strong, irregular ring of bone, on the upper edge of Avhich the spine rests, and from the sides of Avhich the legs spring, forms the center of the skeleton. A broad bone Avas avant- ed here, to connect the central column of the spine Avith the late- ral column of the legs; and a circle Avas the lightest and strongest. If Ave attempt, still further, to conceive Iioav the circle could be modified to fit it for the spine to rest on, for the thighs to roll in, for muscles to hold by, (both above and beloAv,) for the person to sit on—Ave shall find, on inspection, that all our anticipations are realized in the most perfect manner. In the pelvis, too, we have the thyroid hole and ischiatic notches, furnishing subordinate in- stances of contrivance to save material and Aveight: they are mere- ly deficiencies of bone, Avhere solidity could not have given addi- tional strength. The broad ring of the pelvis protects most se- curely the important organs placed Avithin it. The hip-joint exhibits the perfection of the ball and socket ar- ticulation. It alloAvs the foot to move round in a circle, as Avell as to have the great range of backAvard and fonvard motion exhibited in the action of Avalking. When Ave see the elastic, tough, smooth cartilage, which lines the deep socket of this joint, and the simi- lar glistening covering of the ball or head of the thigh bone, and the lubricating synovia poured into the cavity by appropriate se- cretaries, and the strong ligaments giving strength all around, Ave feel hoAV far the most perfect of man's works fall short of the me- chanism displayed by nature. The thigh-bone is remarkable for its projections, called tro- chanters, to Avhich the moving muscles are fixed, and which length- en considerably the lever by Avhich the muscles Avork. The shaft of the bone is not straight, but has a considerable forAvard curva- ture. Short-sightedness might suppose this a Aveakness, because the bone is a pillar supporting a Aveight; but the bend gives it, in MECHANISM OF THE HUMAN SKELETON. 389 reality, the strength of the arch, to bear the action of the mass of muscle called vastus, Avhich lies and SAvells upon its fore-part. The knee is a hinge-joint of complicated structure, and it claims the most attentive study of the surgeon. The rubbing parts are flat and shalloAV, and therefore the joint has little strength from form; but it derives security from the numerous and singularly strong ligaments which surround it. The ligaments on the inside of the knees, resemble, in two circumstacces, the angular liga- ments of joints—namely, in having a constant and great strain to bear, and yet in becoming stronger always as the strain increases. The line of the leg, even in the most perfect shape, bends inward a little at the knee, requiring the support of the ligaments; and, in many persons, it bends very much; but the inclination does not increase Avith age. The legs of many Aveakly in-kneed children, become straight by exercise alone. This inclination at the middle joint of the leg, by throAving a certain strain on the ligaments, gives an increase of elasticity to the limb, in the actions of jump- ing, running, etc. In the knee, there is a singular provision of loose cartilages, which have been called friction-cartilages, from a supposed relation in use to friction-wheels; but their real effect seems to be to accommodate, in the different positions of the joint, the surfaces of the rubbing bones to each other. The great mus- cles on the forepart of the thigh, are contracted into a tendon, a little above the knee, and have to pass over, and in front of the knee, to reach the top of the leg, where their attachment is. The tendon, in passing over the joint, becomes bony, and forms the patella, or knee-pan, often called the pulley of the knee. This peculiarity enables the muscles to act more advantageously, by in- creasing the distance of the scope from the center of motion. The patella is, moreover, a sort of shield, or protection to the forepart of this important joint. The leg below the knee, like the fore-arm already described, has two bones. They offer spacious surface of origin for the nu- merous muscles required for the feet; and they form a compound pillar of greater strength, than the same quantity of bone as one shaft would have had. The individual bones, also, are angular, instead of round—hence deriving greater power to resist blows, etc. 390 PHYSIOLOGICAL. The ankle-joint is a perfect hinge, of srreat strength. There is in front of it an annular ligament, by which the greater part of the tendons, passing doAvmvards to the foot and toes, arc kept in their places. One of these tendons passes under the bony projec- tion of the inner ankle, in a smooth appropriate groove, exactly as if a little fixed pulley Avere there. The heel, by projecting so far backwards, is a lever for the strong muscles to act by, which form the calf of the leg, and ter- minate in the tendo-achillis. These muscles, by drawing at it, lift the body, in the actions of standing on the toes, walking, dancing, etc. In the foot of the negro, the heel is so long as to be ugly, in European estimation; and its great length rendering the effort of smaller muscles sufficient for the various purposes, the calf of the leg in the negro is smaller, in proportion, than in other races of men. The arch of the foot is to be noticed as another of the many provisions for saving the body from shocks, by the elasticity of the supports. The heels and the balls of the toes are the two ex- tremities of the elastic arch, and the leg rests betAveen them. Con- nected Avith elasticity, it is interesting to remark hoAV imperfectly a Avooden leg1 answers the purpose of a natural leg. With the wooden leg, Avhich ahvays remains of the same length, the center of the body must describe, at each step, a portion of a circle, of Avhich the bottom knob of the leg is the center, and the body is therefore constantly rising and falling; Avhile, with the natural legs, Avhich", by gentle flexure at the knee, are made shorter or longer, in different :parts of the step, as required, the body is car- ried along in a manner perfectly level. In like manner, a man riding on horseback, if he keep his back upright and stiff, is jolted by every step of the trotting animal; but the experienced horse- man, even Avithout rising in the stirrups, by letting the back yield a little at each movement, as a bent spring yields during the motion of a carriage, can carry his head quite smoothly along. In a general revieAV of the skeleton, Ave have to remark, 1. The nice adaptation of all the parts to each other, and to the strains Avhich they have respectively to bear; as in the size of the MECHANISM OF THE HUMAN SKELETON. 391 spinal vertebra, increasing from above downwards, the bones of the leg being larger than those of the arm, and so on. 2. The objects of strength and lightness combined, as by the hollowness of the long bones ; their angular form, their thicken- ing and flexures in particular places where great strain has to be borne; the enlargement of the extremities to which the muscles are attached, lengthening the lever by Avhich these act. 3. We have to remark the nature and strength of material in different parts, so admirably adapted to the purposes which the parts serve. There is a bone, for instance, in one place, nearly as hard as iron, where, covered with enamel, it has the form of teeth, Avith the office of chewing and tearing all kinds of matter used as food. In the cranium, again, bone is softer, but tough and resist- ing ; in the middle of long bones, it is compact and little bulky, to leave room for the SAvelling of the muscles lying there ; Avhile, at either end, it is large and spongy, with the same quantity of mat- ter, to give a broad surface for articulation; and, in the spftie, the bodies of the vertebra, which rest on an elastic bed of intevertebral substance, are light and spongy, while their articulating surfaces and processes are very hard. In the joints, we see the tough, elastic, smooth substance, called cartilage, covering the ends of the bones, defending and padding them, and destroying friction. In infants, we find all the bones soft or gristly, and therefore calcu- lated to bear, with impunity, the falls and blows unavoidable at their age ; and we see certain parts remaining cartilage or gristle for life, where their elasticity is necessary or useful, as at the an- terior extremities of the ribs. About the joints, Ave have to re- mark the ligaments, which bind the bones together, possessing a tenacity, scarcely equalled in any other known substance ; and we see that the muscular fibres, Avhose contractions1 .move the bones, and thereby the body—because they would have made the limbs clumsy, everi to deformity, had they all passed over the joints, to the parts which they have to pull—attach themselves, at convenient distances, to a strong cord called a tendon, by means of Avhich, like a hundred sailors at a rope, they make their effort effective at any distance. The tendons are remarkable for the great strength which resides in their slender forms, and for the lu- bricated smoothness of their surfaces. Many other striking parti- culars might be enumerated; but these may suffice. Such, then, 392 PHYSIOLOGICAL. is the skeleton, or general frame-AVork of the human body; loss curious and complicated, perhaps, than some other parts of the system, but so perfect and so Avonderful, that the mind Avhich can attentively consider it Avithout emotion, is in a state not to be en- vied. The living force of man has been used as a Avorking poAver in various Avays, as in turning a Avinch, pulling at a rope, Avalking in the inside of a large wheel to move it, as a squirrel or turn-spit dog moves his little Avheel, etc. Each of these has some particu- lar advantage ; but that made in Avhich, for many purposes, the greatest effect may be produced, is for the man to carry up to a hight his body only, and then to let it Avork by its Aveight in de- scending. A bricklayer's laborer Avould be able to lift twice as many bricks to the top of a house, in the course of a day, by as- cending a ladder Avithout a load, and raising bricks of nearly his own Aveight, over a pully each time in descending, as he can by carrying bricks and himself up together, and descending again Avithout a load, as is still usually done. Reflection Avould natu- rally anticipate the above result, independently of experiment; for the load Avhich a man should be best able to carry, is surely from Avhich he can never free himself—the load of his OAvn body. Accordingly, the strength of muscles and disposition of parts, are all such as to make his body appear light to him. The ques- tion Avhich Avas agitated with such warmth sometime ago, as to the propriety of making men and Avomen Avork on the tread-mill, re- ceives an easy decision here. They Avork by climbing on the out- side of a large wheel or cylinder, Avhich is turned by their weight, and on Avhich they must advance just as fast as it turns, to avoid falling from their proper situation. There are projections or steps for the feet on the a outside of the cylinder, and the action to the Avorkers is exactly that of ascending an aclivity. Now, as nature has fitted the human body for^climbing hills, as Avell as for walking on plains, the Avork of the tread-mill, under proper restrictions as to duration, must be as natural and healthful as any other. Its effects have now proved it to be so. As animal power is exhaust- ed exactly in proportion to the time during Avhich it is acting, as Avell as in proportion to the intensity of force exerted, there may often be a great saving of it by doing Avork quickly, although with a little more exertion during the time. Suppose two men of equal Aveight to ascend the same stairs, one of Avhom takes only a min- MECHANISM OF THE HUMAN SKELETON. 393 ute to reach the top, and the other takes four minutes ; it will cost the first but a little more than a fourth part of the fatigue which it cost the second, because the exhaustion has relation to the time during which the muscles are acting. The quick mover may have exerted, perhaps, one twentieth more force in the first in- stant, to give his body greater velocity, which Avas afterwards continued : but the sloth supported his load four times as long. A healthy man will run rapidly up a long stair, and his breath- ing will scarcely be quickened at the top ; but if he Avalk up slow- ly, his legs will feel fatigued, and he will have to wait sometime, before he can speak calmly. For this same reason, coach-horses are much spared by being made to gallop up a short hill, and be- ing then alloAved to go more sloAvly for a little time, so as to rest at the top. The rapid waste of muscular strength, which arises from continued action, is shoAvn, by keeping the arm extended horizontally for some time ; few can continue the exertion beyond a minute or two. In animals which have long horizontal necks, there are provisions of nature in a strong elastic substance on the back or upper part of the neck, which nearly supports the head, independently of muscular exertion. 50 394 PHYSIOLOGICAL. HEART. A hollow, muscular organ, the function of which is to maintain the circulation of the blood, and which is of different formations in different animals. The organs of circulation are the heart, the arteries, the veins, and the capillary vessels. The blood is divided into the arterial blood and the venous blood. The object of the circulation is to carry the venous blood, which has returned from the body, into the lungs, where, by the influence of the air, it is converted into arterial blood, Avhich is then again sent out into the system to nou- rish it and repair its losses. The heart in men, quadrupeds, and birds, is composed of four cavities, two auricles, and two ventricles, (thence called double.) It is enveloped in a membrane called the pericardium, situated toward the left of the cavity of the chest, be- tAveen the lungs, and resting on the diaphragm. Its form is that of a cone flattened on its inferior and superior faces, the latter formed principally by the right, the former by the left, auricle and ventricle. The right auricle communicates with the right ventricle, besides Avhich there are in it three openings : that of the vena cava inferior; that of the vena cava superior ; and that of the coronary vein. The communication between this auricle and ventricle is closed by a valve when the heart contracts ; the right or pulmonary ventricle communicates Avith the pulmonary artery, which is provided Avith three valves. When these valves are brouglit together, they interrupt the communications betAveen the ventricles and the artery. The left auricle communicates with the left ventricle, and contains, also, the orifices of the four pulmonary veins. The left ventricle, besides the communication with the left aricle, contain the orifice of the aorta. The ventricles are divided from each other by a fleshy Avail, called the septum cordis. The valves, at the opening of the arteries, are called semi-lunar ; that at the orifice of the right auricle, tricuspid; that at the orifice of the left auricle, mitral; and that at the orifice of the vena cava inferior, the eustachian valve. The heart is formed of a firm, thick, muscular tissue, composed of fibers interlacing with each other. It is also composed of nerves, membranes, and vessels. The coronary arteries arise from the aorta, and are distributed on the heart. The coronary veins re- HEART. 395 turn the blood of the heart into the right auricle. The arteries are the vessels which serve to carry the blood from the heart to all parts of the body; they terminate in the capillary vessels, a series of extremely minute vessels, Avhich pass over into the veins. The veins are the channels by which the blood passes back from the body into the auricles of the heart. The blood which is re- turned from the veins is black, and is called venous ; that Avhich leaves the heart is red, and is called arterial. The red blood, po- sessing nourishing and vital properties, rises in the capillary sys- tem of the lungs, flows into the pulmonary veins, thence is recei- ved into the left cavities of the heart, from which it passes into the aorta, and is transmitted to all parts of the body, to the capil- lary system. It there loses two degrees of temperature, and un- dergoes other changes, by the loss of some of its elements, in the important functions of nutriment, calorification, and the secretions. It has now become black, passes through the veins, from the extre- mity of the body, towards the heart, receives the chyle and the lymph, and is emptied into the right cavities of that organ Which returns it through the pulmonary artery to the capillary vessels of the lungs, where it is subjected to the influence of the air, resumes the qualities of red or arterial blood, and is ready for a neAV course. Having thus described the rout of the blood through the different parts of the system, we will now explain the mechanism of the sanguineous system. The blood contained in the two venae cavae is poured into the right auricle, which contracts, and thus forces the fluid to escape ; but the vena cava superior opposes to its pas- sage the column of blood which it contains ; the other veins are closed by valves, and it must, therefore, pass into the right ven- tricle. The ventricle then contracts, and the tricuspid valve clo- sing the passage through which the liquid entered, it is forced for- ward into the pulmonary artery, which contracts, and its orifice being closed by the semi-lunar valve, propels the blood still for- ward into the capillary system of the lungs, whence it passes into the pulmonary veins, which pour it into the left auricle by their four orifices. The contraction of the auricle impels it into the left ventricle, by which it is, in the same manner, driven forward into the aorta, (the mitral valve preventing its return into the au- ricle,) and thence into the general circulation, as above described. The two auricles contract and dilate simultaneously with each 396 PHYSIOLOGICAL. other, as do also the two ventricles. The dilatation is called dias- tole; the contraction, systole. It is difficult to determine what. quantity of blood the heart projects at each systole. It is general- ly estimated at two ounces. The causes of the alternate contraction and dilatation of the heart are not less difficult to decide. They are entirely involun- tary and dependent on the nervous system. The force of its con- traction is likeAvise unknoAvn. The systole of the ventricles is the cause of the motion of the blood in the arteries, which also dilate Avith each Avave driven into them by the motion of the heart. By Avhat means the blood is made to penetrate the thousand Avind- ings of the capillary system, and what causes impel it to Aoav back through the veins, are yet subjects of dispute among physiologists. The time in Avhich a drop of blood completes its circle of motion, has been differently estimated at from tAvo minutes to tAventy-four hours. Among the loAver orders of animals, the organization of the cir- culating system is very different. The infusoria, polypi, and in- testinal Avorms, have no distinct vessels, much less a heart. The echinodermata have distinct organs of circulation, but no part re- sembling a heart. Insects have a small cylindrical vessel running along the back, which is rather the rudiment of a vascular system than of a heart. The first traces of a heart are found in some Avorms in which some expansions are perceptible in a part of the vessel which runs the Avhole length of the body. In the spider, lateral vessels are given off from the main vessel, and a pulsation is perceptible. The crustacea have a heart composed of one fleshy ventricle. In the mollusca, the heart appears completely formed : some of them have three cavities. The four classes of vertebral animals have red blood; but fishes and reptiles have only what is called a single heart, that is composed of one auricle and one ventricle. LUNGS. The organs of respiration in the mammalia, (man, quadrupeds, and the cetaceous animals,) birds and reptiles. The lungs are LUNGS. 397 situated within the chest, and are divided into tAvo parts, called lobes. They are enveloped in a delicate and transparent mem- brane, derived from the pleura, through which they have the ap- pearance of network, and are connected Avith the spine by the pleura, with the neck by the windpipe, and with the heart by the roots of the pulmonary artery and veins. In their specific gravity, they are the lightest of all the animal organs, even when exhaust- ed of air; hence their name of lights. To the touch they are soft, spongy and elastic. In their internal structure, they are composed of an infinite number of membraneous celled blood- vessels, nerves and lymphatics, all connected by cellular substance; small tubes arise from them, Avhich are finally united into one large tube from each lobe, and these two at length join to form the windpipe. The blood-vessels, called the pulmonary vessels, are destined to distribute the blood through the cells, for the purpose of sub- jecting it to the action of the air; while the bronchial vessels are intended to supply the blood which nourishes the lungs. The ce- tacea whales and seals breathe by lungs, and are therefore obliged to ascend, at intervals, to the surface of the water, to obtain a sup- ply of atmospheric air. The respiratory orifice, in these animals, is not situated at the extremity of the snout, but on the top of the head. In birds, the lungs are smaller than in quadrupeds ; but they have air distributed throughout their muscular system, and in the cavities of the bones. The lungs afford the means of ascertaining whether a new-born child, which is found dead, was, or Avas not living, when born ; a question often of great importance in forensic medicine. The lungs of the infant are placed in water, to see whether they will swim or sink. Before birth, the lungs are dark red, contracted into a small place within the cavity of the breast, firm, and speci- fically heavier than Avater. They therefore sink in Avater, whether they are entire, or cut into pieces ; and Avhen cut, no air-bubbles come forth, either in or out of the Avater, nor does much blood ap- pear. But if the babe has lived afterbirth, and therefore breathed, air has entered the lungs; has thus enlarged the cavity of the chest, and the lungs themselves are expanded, and appear of a 398 PHYSIOLOGICAL. loose, spongy t exture; of a pale red color, and cover the heart and fill the chest. They then sAvim in Avater, as Avell in connec- tion with the heart, as Avithout it; as well entire, as in pieces. If cut, a peculiar sound is audible ; air proceeds from them, and rises, if they are pressed under water, in small bubbles. From the in- cisions in the lungs, red, and, generally, foamy blood issues. Against this test it has been objected, 1st, That air may be found in the lungs, though the infant never breathed. This could hap- pen, hoAvever, only from air having been blown into them ; but, in this case, the chest of the infant is not arched ; very little blood is to be found in the lungs, and it is not bright red, nor foamy from putrefaction; but in this case, the other parts of the body Avould also be affected by putrefaction ; the lungs are not expand- ed ; pale red; air-bubbles show themselves only on the surface, and not in the interior substance, unless the highest degree of pu- trefaction has taken place. 2d. It is said that the child may have breathed, and therefore lived, without air being found in the lungs. This is not proved, and is at variance with the received ideas of the manifestation of life. 3d. That part of the lungs may swim, another may sink. This can happen only Avith lungs in a dis- eased state, and Avould only prove an attempt of the infant to breathe, without the possibility of living. 4th. That a child may have lived without breathing; but this state of apparent death can- not be called life. Life cannot be supposed Avithout breath. If all precautions are taken; all attending circumstances considered ; the external appearance of the infant Avell observed, and the state of the other intestines examined, the foregoing test may be consider- ed as sufficient for the decision of the question, whether a child has lived after birth, or not. Another kind of test, by means of the lungs, has been proposed, Avhich is founded on the proportion of the weight of the whole body to a lung Avhich has breathed, and one which has not; and still another, which rests on the cir- cumference of the chest, before and after breathing has commenced. But both are more complicated, troublesome, and less certain than the former one. BREATH.--HEAD. 399 BREATH. The air which issues from the lungs, during respiration through the nose and mouth. This operation is performed without effort, but still it causes a motion in the external air, before the nose and mouth. The air expired is the vehicle of sound and speech. A smaller portion of oxygen and of carbonic acid is contained in the air which is exhaled, than in that which is inhaled. There are, also, aqueous particles in the-'breath, Avhich are precipitated, by the cold- ness of the external air, in the form of visible vapor; likewise other substances which OAve their origin to secretion in the mouth, nose, windpipe, and lungs. These cause the changes in the breath, which may be known by the smell, like the other qualities of the air. In youth, the breath is insipid, and contains acid; it loses these qualities, after the age of puberty, and becomes more agreeable. With advancing age, it becomes again unpleasant. A bad breath is often caused by local affections in the nose, the mouth, or the windpipe: viz. by ulcers in the nose, cancerous polypi, by dis- charges from the mouth, by sores on the lungs, or peculiar secre- tions in them. It Is also caused by rotten teeth, by impurities in the mouth, by many kinds of food, and by fevers. In the last case, it often varies Avith the character of the disease. The re- medy for this complaint must depend on the causes which pro- duce it. Substances of an aromatic kind, which have a strong, rich smell, should be cheAved to diminish their offensiveness. But it is often impossible to remove this unpleasant disorder. Accord- ing to the Prussian code, a bad breath furnishes ground for a di- vorce. HEAD. The part of the animal body which contains the brain, and the higher organs of sense. In many animals it is connected with the trunk, by the R3ck, and is more or less moveable, and is mere- ly a prolongation of the trunk. The head, in animals, is more 400 PHYSIOLOGICAL. distinct in proportion, as the brain is more fully developed as the center of the nervous system. It is entirely wanting in the loAvest classes of animals, Avhich, therefore, from the intestinal Avorms doAviiAvard, form a third class, in the system of Latreille, under the name of acephala, (headless animals;) Avhile those provided Avith heads are divided into tAvo classes, the vertebral animals, having distinct and proper heads, and the cephedidia, having small and less distinctly formed heads. In this part the mouth, as the opening of the esophagus, is ahvays situated. In the second class of animals, in Avhich the head is less distinct, that part of the body Avhich is provided Avith the mouth, may be called the head end. In the vertebral animals, (mammalia, birds, reptiles, and fish,) the head has a bony basis, (cartilaginous only in the carti- laginous fishes.) In fishes, the bones of the head are not united Avith each other; and the formation of the separate bones is va- rious. In cartilaginous fishes, the head is more or less oblong and angular; in osseous fishes it is less flattened, and composed of a considerable number of bones, connected in various ways. In all fishes, the cavity of the brain is very small and oblong. Equally various is the formation of the head in the different classes of reptiles. In general, the head is composed of few bones, and more rounded in proportion, as the brain is more developed. In birds, the bones of the head are more closely formed into one whole, constituting a skull more or less round, Avhich contains the brain, and to the forepart of which, the back is attached. But the head is most perfect in the mammalia, and resembles the hu- man head more nearly, as the animal approaches more nearly to man. In general, the human head may be considered as the standard, which may be traced with gradual deviations, through the different classes, until it entirely ceases, in the lower orders of animals. NoAvhere is its proper office, to serve for the reception of the nervous system, so distinct as in the human head; the ca- vity of the skull containing the principal organ of sensitive life— the brain; as the great cavities of the trunk contain the chest, the organs of irritable life, (the heart and lungs,) and the abdominal cavity, the organs of the reproductive life, (the organs of diges- tion and generation.) The superiority of the head over the other two parts just men- tioned, appears also from the circumstance, that whilst it is pre- BRAIN. 401 eminently the seat of the nervous system, it also contains organs essential for functions of the irritable and reproductive system; as the inspiration and expiration of the air are effected through the nostrils and mouth, and the entrance of food into the abdominal cavity, as well as the preparation of it for digestion, by mastica- tion and the production of saliva, is effected by the mouth; and these organs appear more prominent, in the heads of animals, as their sensitive system sinks lower in the scale. It must not be for- gotten, that the head also contains the tongue, an organ not only important in respect to nourishment, but also communicating the desires and thoughts, until it becomes, in man, the organ of oral intercourse, of language, and of the finest music—singing. The human head, and, more or less, the head of other animals, is divided into two chief parts, the skull and the face. The im- portance of the head, as the noblest part of the animal system, has occasioned it to be used metaphorically, in all languages, to denote that Avhich is chief. BRAIN. The brain is a soft substance, partly reddish-gray and partly whitish, situated in the skull, penetrated by numerous veins, and invested by several membranes. Democritus and Anaxagoras dis- sected this organ, almost three thousand years ago. Haller, Vicq d'Azir, and other anatomists in modern times, have also dissected and investigated it, without exhausting the subject. Between the skull and the substance of the brain, three mem- branes are found. The outer one is called the dura mater. This is strong, dense, and elastic. It invests and supports the brain. The next which we meet is the tunica arachnoidea. This is of a pale white color, yet in some degree transparent, very thin, and, in a healthy state, exhibits no appearance of vessels. The mem- brane below this, is called the pia mater. It covers the whole surface of the brain. It is very vascular, and a great portion of the blood Avhich the brain receives, is spread out upon its surface, in minute vessels. 51 402 PHYSIOLOGICAL. The brain consists of two principal parts, connected by delicate veins and fibers. The larger portion, the cerebrum, occupies, in men, the upper part of the head, and is seven or eight times larger than the other, the cerebellum, lying behind and beloAV it. It rests on the bones Avhich form the cavities of the eyes, the bottom of the skull, and the tentorium, and projects behind over the cerebel- lum. On the Avhole exterior of the cerebellum, there are convo- lutions, resembling the Avindings of the small intestines. The external reddish substance of the brain is soft and vascular, and is called the cortical substance; the internal is white, and is called the medullary substance of the brain. This medulla consists of fibers, which are very different in different parts. The cerebellum lies beloAV the cerebrum, in a peculiar cavity of the skull. By examining the surface, it is seen to be divided into a right and left lobe, by the spinal marrow lying between, but connected at the top and bottom. Like the cerebrum, it is surrounded by a vascu- lar membrane, reddish-gray on the outside, and composed of a medullary substance within. In proportion to its size, also, it has a more extensive surface, and more of the vascular membrane, than the cerebrum. In a horizontal section of it, Ave find parallel curved portions of the cortical and the medullary substances alter- nating Avith each other. Between the cortical and the medullary substances, there is always found, in the cerebellum, a third inter- mediate yellow substance. All the medulla of the cerebellum is also united in the middle by a thick cord. Experience teaches, that in the structure of the brain, irregulari- ties are far more uncommon than in other parts of the human body. It is worthy of observation, that every part of the brain is exactly symmetrical Avith the parts opposite. Even those which lie in the middle, and are apparently single, consist, in fact, of two sym- metrical portions. The total weight of the human brain is esti- mated at two or three pounds. It is larger and heavier in propor- tion to the youth of the subject; and in old age it becomes speci- fically lighter. In delirious affections, it is sometimes harder, and sometimes less solid, and softer. The brain is the organ of sensa- tion, and, consequently, the material representative of the soul, and the noblest organ of the body. NERVES. 403 NERVES. The nerves of the animal frame are composed of bundles of white parallel medullary threads. Every bundle is surrounded with a soft sheath full of bloodvessels, and whose finest branches terminate in the substance of the nerves. These nerves are spread through the whole animal frame, and variously connected with each other. Only the epidermis, hair, and nails are destitute of them. They are of various sizes, according as they are composed of more or fewer bundles of medullary threads. In the course of the nerves, there are a number of knots, these are called ganglions ; they are commonly of an oblong shape, and of a grayish color, somewhat inclining to red, which is, perhaps, owing to their being extremely vascular. In particular parts of the body, the nerves come in con- tact Avith each other, and the bundles composing them are mutu- ally interwoven to such a degree that they cannot be disjoined Avith- out violence. These communications are called plexuses, and are found particularly in the abdomen, behind the stomach, and in the region of the pit of the stomach, near the liver, mesentery, heart, etc. The final terminations of these nerves are various; particularly those which run to the organs of sense. In the auri- cular organ, for instance, the nerves terminate in a soft mass, like pap, surrounded with moisture; the optic nerve terminates in a medullary skin; the nerves of taste terminate in little papillae; those of feeling, in the points of the fingers, and the surface of the skin in general; those belonging to the muscles are lost in the tex- ture of the same, so that their termination cannot be correctly as- certained. All the nerves are embraced under the general head of the nervous system. This is most intimately connected Avith the brain and spinal marrow, which may be regarded as a prolonga- tion of it. The brain is the center from which, or to which, proceed all impressions communicated to the nerves. The substance of the nerves is the same medullary matter which constitutes the brain, resembling the white of an egg, and appearing, to the unassisted eye, as if composed of little balls. The central termination of all the nerves is in the brain and spinal marrow, where they branch out into the skin, or interior of the organs. The various isolated 404 PHYSIOLOGICAL. and, in part, heterogeneous structures of which the body consists, Avhich are mechanically joined by the cellular tissue, the mem- branes and ligaments, are united into one harmonious Avhole by means of the nerves. The vascular system connects them only so far as it supplies the blood required for their support and their operations ; but it is properly the nervous system that imparts to all their life, governs their operations, and establishes their sym- pathy and mutual action. This is effected by means of that por- tion of the nervous system Avhich is diffused through the abdomen, forming many nets and plexuses, and constituting what is called vegetative, or reproductive, or organic nervous system, because the growth and support of the body are effected by it. Another part of the nervous system affords the means of consciousness and voluntary action. This is the brain, or cerebral system, which ex- cites the nerves that put in action the muscles of voluntary mo- tion, and those which supply sensibility to the organs of sense, and convey to the brain the impressions thence received. The nerves which communicate with the organs of sense run in pairs : the first pair (olfactory nerve) to the nose, where it is spread over the surface of the nostrils, and forms the poAver of smell; the second (optic nerve) to the eyes; this is round, thick, and pene- trates from behind the ball or globe of the eye, through a round plate of the firm coat of the ball containing many little apertures, and is spread out on the inner and concave surface of the globe into a thin coat called the retina, on which the images of external objects are formed; the eighth pair (auditory nerves) are spread over the interior of the ear, and are sensible to the vibrations of the air. From the numerous ramifications of the ninth pair come the nerves of the tongue, which give rise to the sense of taste. The general sense of feeling is situated particularly in the skin, and peculiarlyin the points of the fingers. This sense is produced by a variety of nerves diffused over the skin, and those parts which are most sensitive are supplied with the greatest quantity of nerves, which form entire series of contiguous nervous papillae; for in- stance, at the lips, the points of the fingers, etc. Thus the action of the nerves is reciprocal from Avithout inAvards, and from Avithin outwards ; the first, because the impressions on the organs of sense are communicated, by the nerves, to the brain, and there form per- ceptions and feelings; the second, because the voluntary motions EAR. 405 are produced by communications from the brains to the nerves, while the reproductive part of the nervous system quietly supports the whole machine, and, in a sound state of the body, is recognised only by the operation of the appetites, and by a general feeling of ease throughout the system ; but, in a diseased state, gives rise to general uneasiness and pain. The power of the nervous system has no fixed point, but is variable even in the same subject. In sleep, the activity of the cerebral system is impaired; that of the reproductive system heightened; therefore, in quiet sleep, the operations of the senses and voluntary motions cease, while the activity of the organs of respiration and circulation, of digestion, se- cretion, and nourishment, continues. From what has been said, it appears that the Avhole action of the body depends upon the ner- vous system. EAR. The ear is the organ of hearing. It is situated at the side of the head, and is divided into external and internal ear. The au- ricula, or pinna, commonly called the ear, constitutes the exter- nal part. It is of a greater or less size, according to the individ- ual. The pinna is formed of a fibrous cartilage, elastic and pliant. The skin Avhich covers it is thin and dry. There are also seen, upon the different projections of the cartilaginous ear, certain mus- cular fibers, to which the name of muscles has been given. The pinna, receiving many vessels and nerves, is very sensible, and easily becomes red. It is fixed to the head by the cellular tissue, and by muscles, which are called, according to their positions, an- terior, superior, ox posterior. These muscles are much developed in many animals ; in man, they may be considered as simple ves- tiges. The meatus auditorius, or auditory passage, extends from the concha to the membrane of the tympanum; its length, variable according to age, is from ten to twelve lines in the adult; it is narrower in the middle than at the ends ; it presents a slight curve above, and in front. Its external orifice is commonly covered 406 PHYSIOLOGICAL. Avith hairs, like the entrance to the other cavities. The middle ear comprehends the cavity of the tympanum, the little bones Avhich are contained in this cavity, the mastoid cells, the eusta- chian tube, etc. The tympanum is a cavity Avhich separates the external, from the internal ear. Its form is that of a portion of a cylinder, but a little irregular. The external side presents the membrana tympani. This membrane is directed obliquely doAvn- Avard and inward ; it is bent, very slender and transparent, covered on the outside by a continuation of the skin ; on the inside, by the narroAv membrane which covers the tympanum. Its tissue is dry, brittle, and has nothing analagous in the animal economy; there are neither fibers, vessels or nerves found in it. The cavity of the tympanum, and all the canals Avhich end there, are covered with a very slender mucous membrane ; this cavity, which is al- ways full of air, contains, besides, four small bones (which form a chain from the membrana tympani to the fenestra ovalis,) where the base of the stapes is fixed. There are some little muscles, for the purpose of moving this osseous chain ; of stretching and slackening the membranes to Avhich it is attached; thus the internal muscle of the malleus draws it forward ; bends the chain in this direction, and stretches the membrane ; the anterior muscle produces the contrary effect. It is also supposed that the small muscle which is placed in the pyramid, and Avhich is attached to the neck of the stapes, may give a slight tension to the chain, in drawing it to- Avards itself. The internal ear, or labyrinth, is composed by the cochlea, of the semicircular canals, and of the vestibule. The cochlea is a bony cavity, in form of a spiral, from which it has taken its name. This cavity is divided into two others, which are distinguished in- to external and internal. The partition Avhich separates them, is a plate, set edgeAvays, and Avhich, in its whole length, is partly bony, and partly membranous. The semicircular canals are three cylindrical cavities, bent into a semicircular form, two of which are disposed horizontally, and the others vertically. These canals terminate by their extremities in the vestibule. They con- tain bodies of a gray color, the extremities of which are terminat- ed by swellings. The vestibule is the central cavity; the point of union for all the others. It communicates Avith the tympanum, the cochlea, the semicircular canals, and the internal meatus audi- THE APPENDAGES OF THE HUMAN EYE. 407 torius, by a great number of little openings, The cavities of the internal ear are entirely hollowed out of the hardest part of the temporal bone; they are covered with an extremely thin mem- brane, and are full of a very thin and limpid fluid; they contain, besides, the acoustic nerve. The internal ear and middle ear are traversed by several nervous threads; the presence of which is, perhaps, useful to hearing. THE APPENDAGES OF THE HUMAN EYE. The appendages of the eye, says Dr. J. Bryan, are almost as important to sight, in the human family, as the eye itself. The eye-ball, placed in a socket called the orbit, is moved in various directions, by means of six muscles, four of Avhich are straight, and taking their origin from the back part of the orbit, around the foramen through which the optic nerve enters, extend forward, and are inserted into the eye-ball, just back of the cornea. The position of these muscles is such, as to produce four movements of the eye, the superior one being inserted into the upper surface, the inferior one into the lower, and the remaining two, one each side, so that, by their contractions, they produce movements, first upwards, second downards, third outwards, and fourth towards the nose, or inwards. The other two muscles are called the ob- lique, from their producing oblique motions of the eye; the larger one running through a little loop, just under the internal angle of the eye, takes its origin from the four straight ones, at the back part of the orbit, and, after going through the loop, extends back- wards, and is inserted in the upper part of the eye. This muscle, in animal mechanics, is a complete example of a tackle or pulley. The other oblique muscle is much shorter, and takes its origin from the anterior or middle part of the orbit, and extending out- Avards, is inserted into the external side of the eye: when it con- tracts, it draws the eye obliquely inward and downward, produc- ing, when two strong for its antagonist, squinting; to cure squint- ing, therefore, in children, we must strengthen the antagonist muscles, so that one shall not overpower the other: this is done, 408 PHYSIOLOGICAL. of course, by bringing the Aveaker muscle or muscles into active exercise. The whole eye-ball is enveloped in a soft cushion of fat, so that it is moved, in every direction, Avith the greatest facility. In studying the comparative anatomy of the eye, Ave are struck Avith the various and curious means resorted to, to give it motion; in some, it is placed, as it Avere, on the end of the arm, Avhich is thrust out to reconnoiter; in others, (the spider for instance,) the number is multiplied, and each one is stationary, etc., etc. The eye is kept moist and transparent by means of the lachry- mal fluid; it is secreted by a gland situated under the external angle of each eye, that is called the lachrymal gland, and transmits the fluid, Avhen secreted, over the eye through the small tubes, Avhich open on the internal surface of the upper lid; it is further spread and made to moisten the Avhole anterior of the eye, by the motion of the lids; the lids are formed of skin, fatty matter, and a carti- lage of gristly substance, called the tarsal cartilage. The edges of the lids are fringed by beautiful, irregular rows of hairs, which, in the upper lids, are turned upAvards, and the lower ones downwards, so that, when the lids are closed, the convex surface of the hairs are brought together, but they do not intermix. This beautiful arrangement assists very much in protecting the eye from dust, perspiration, etc. The internal surface of the lids, and all the anterior parts of the eye, are covered by a very fine membrane, called tunica conjunctiva, which prevents extraneous matter from going father than just under the lids, and generally under the up- per one; this, Avhen it is some light or smooth substance, is re- medied by raising the upper lid, and draAving it over the lower one, the convex hairs of which, make an admirable brush to sweep the eye. Between the union of the lids on the nasal side, there is a little projection, called caruncular lachrymalis. In some animals this is enlarged, and forms what is, in fact, a neAv eye-lid, called mem- brana nictitans. The motion of the lids is chiefly in the upper one, hence this has a distinct muscle of its own, Avhich, taking its origin near the optic foramen, Avith the muscles of the eye-ball, is inserted into the substance of the lid, and is called the levator pal- pebra. Another secretory apparatus is composed of a series of small glands, which are named, in compliment to the anatomist THE APPENDAGES OF THE HUMAN EYE. 409 who first described them, Merbomean. When the eye-lids are inverted, these glands will be seen, in parallel rows, on the sur- face of the cartilages, and under the conjunctiva; each of them opens on the margin of the eye-lid by a separate duct. It is in- flammation of one these small glands, which causes the common disease, stye. The secretions from these glands seem to increase at night, and in children, and those who have inflamed eyes, the lids are often glued together in the morning. From what has been said above, we are noAV prepared to understand the manner by Avhich the eye is kept moist. When this moisture becomes re- dundant, it is carried off by the following means. On the edge of each groove, which, coming in opposition to its felloAV, assists in forming a canal Avhich extends from the outer to the inner an- gle of the eye, the fluid secreted by the lachrymal gland, and spread over the eye in the way above mentioned, is collected m this^canal, and passes along it to the inner angle, where two small tubes take it up, (one in each,) and convey it to a third, called the lachrymal sac, Avhich empties in the nose; hence, Avhen an excess of tears is secreted, the nose is incommoded, and snuffling in children is the result. The broAV is designed to protect the eye by shading it, and oth- erAvise. The hair in the broAvs does not groAv straight out, like that of the head, nor upAvard and downward, as that of the lids, but those of each one groAV outAvard. Much of the beauty and expression of the face depends on the size, color, and form of the broAV. The Romans thought it a mark of comeliness that they should meet. This certainly gave them a more ferocious and war- like air. The Roman ladies painted their broAvs so as to meet, Avhile the fair Greeks kept them separate, and formed them into a beautiful arch, gently terminating into nothing. The separation of the brow with an unfurrowed front, gives a calm and intelligent expression to the countenance. The storms of passion, the writh- ing of pain, etc., are first seen by a second person, in the knitting of the broAV. Knowing the structure of the eye, some of the diseases may be mentioned Avith propriety. The internal coat or retina sometimes becomes diseased, and the sight is lost, or nearly lost, before the patient or his friends are>aAvare of it, there are so feAV outAvard signs, by which a common observer would recognize it. When 410 PHYSIOLOGICAL. the lens becomes diseased or opaque, it must be extracted or cut up, and removed to another part of the eye, so that the natural poAvers of the system may carry it off. The corner is subject to inflammation, ulceration, and opacity, Avhich, of course, when co- extensive, destroy vision. The conjunctiva, Avhen inflamed, pro- duces Avhat, in ordinary language, is emphatically called sore eyes. It frequently becomes red from some slight causes, such as dust under the lids, cold, etc., etc. When the edges of the lids be- come inflamed, the tears do not follow their natural course; and instead of going through the lachrymal sac, flow over the cheek. Many persons inherit weak eyes from their parents, and are sub- ject to an unpleasant overfloAV of tears, from slight causes; such persons frequently ruin their eyes, by trying every nostrum Avhich they hear of, for relief, in vain; eye-Avater, eye-salve, ointment, etc., etc. MUSCLE. The parts that are usually included under this name, consist of distinct portions of flesh, susceptible of contraction and relaxation, the motions of Avhich, in a natural and healthy state, are subject to the Avill; and for this reason, they are called voluntary mus- cles. Besides these, there are other parts of the body that owe their power of contraction to their muscular fibers: thus the heart is a muscular texture, forming Avhat is called a hollow muscle; and the stomach, intestines, etc., are enabled to act upon their con- tents, merely because they are supplied with muscular fibers: these are called involuntary muscles, because their motions are not dependent on the will. The muscles of respiration, being in some degree influenced by the will, are said to have a mixed mo- tion. The names by which the voluntary muscles are distinguished, are founded on their size, figure, situation, use, or the arrangement of their fibers, or their origin and insertion; but besides these par- ticular distinctions, there are certain general ones, that require to be noticed. Thus, if the fibers of a muscle are placed parallel to MUSCLE. 411 each other, in a straight direction, they form Avhat anatomists term a rectilinear muscle; if the fibers cross and intersect each other, they constitute a compound muscle; when the fibers are disposed in the manner of rays^ a radiated muscle; Avhen they are placed obliquely with respect to the tendon, like the plume of a pen, a penniform muscle. Muscles that act in opposition to each other, are termed antagonists: thus, every extensor has a flexor for its antagonist, and vice versa. Muscles that concur in the same ac- tion, are termed congenercs. The muscles being attached to bones, the latter may be considered as levers, that are moved in different directions by the contraction of those organs. That end of the muscle Avhich adheres to the most fixed part, is usually called the origin, and that which adheres to the more movable part, the insertion of the muscle. In almost every muscle, two kinds of fibers are distinguished: the one soft, of a red color, sensible and irritable, called the fleshy fibers; the other of a firmer texture, of a Avhite, glistening color, insensible, without irritability, or the poAver of contracting, called the tendinous fibers. They are oc- casionally intermixed, but the fleshy fibers generally prevail in the belly, or middle part of the muscle, and the tendinous ones in the extremities. If these tendinous fibers are formed into a round, slender cord, they form Avhat is called the tendon of the muscle; on the other hand, if they are spread into a broad, flat surface, they form Avhat is called an aponeurosis. The fibers that com- pose the body of a muscle, are disposed in fasciculi, or bundles, which are easily distinguishable by the naked eye: but these fas- ciculi are divisible into still smaller ones; and these, again, are probably subdivisible ad infinitum. The most minute fiber we are able to trace, seems to be somewhat plaited; these plaits dis- appearing when the fiber is put on the stretch, seem evidently to be the effect of contraction, and have probably induced some wri- ters to assert, that the muscular fiber is twisted, or spiral. A fiber is essentially composed of fibrine and osmazome, receives a great deal of blood, and, at last, one nervous filament. By chimical analysis, muscle is found to consist chiefly of fibrine, Avith albumen, gelatine, extractive, phosphate of soda, phosphate of ammonia, phosphate and carbonate of lime, and sul- phate of potassa. Each muscle is surrounded by a thin and deli- cate covering of cellular membrane, which dipping down into its 412 PHYSIOLOGICAL. substance, incloses the most minute fibers we are able to trace, connecting them Avith each other, lubricating them by means of the fat Avhich its cells contain, in more or less quantity in different subjects, and serving as a support to the blood-vessels, lymphatics, and nerves, Avhich are distributed through the muscles. The mus- cles OAve the red color Avhich so particularly distinguishes their belly part, to an infinite number of arteries, which are everyAvherc dispersed through the Avhole of their reticular substance; for their fibers, after having been macerated in Avater, are (like all other parts of the body divested of their blood) found to be of a Avhite color. The veins, for the most part, accompany the arteries, but are larger and more numerous. The lymphatics are more numer- ous, as might be expected from the great proportion of reticular substance which is everywhere found investing the muscular fibers. The nerves are distributed in such abundance to every muscle, that the muscles of the thumb alone receive a greater proportion of nervous influence than the largest viscera. Muscular Motion.—Muscular motions are of three kinds,— namely: voluntary, involuntary, and mixed. The voluntary mo- tions of muscles proceed from an exertion of the will: thus, the mind directs the arm to be raised or depressed, the knee to be bent, the tongue to be moved, etc. The involuntary motions of mus- cles are performed by organs, Avithout any attention of the mind, as the contraction and dilatation of the heart, arteries, veins, ab- sorbents, stomach, intestines, etc. The mixed motions are those which are in part under the control of the will, but Avhich ordina- rily act Avithout our being conscious of their acting, and are per- ceived in the muscles of respiration, the intercostals, the abdomi- nal muscles, and the diaphragm. When a muscle acts, it becomes shorter and thicker—both its origin and insertion are drawn to- Avards the middle. The sphincter muscles are ahvays in action, and so likewise are antagonist muscles, even when they seem at rest. When tAvo antagonist muscles move with equal force, the part Avhich they are designated to move, remains at rest; but if one of the antagonist muscles remains at rest, while the other acts, the part is moved toAvards the center of motion. When a muscle is divided, it contracts. If a muscle be stretched to a certain ex- tent, it contracts, and endeavors to acquire its former dimensions, as the stretching cause is removed. When a muscle is wounded, MUSCLE. 413 or otherwise irritated, it contracts independently of the will; this power is called irritability, and it is a property peculiar to, and inherent in the muscles. When a muscle.is stimulated, either through the medium of the will, or any foreign body, it contracts, and the contraction is greater or less in proportion as the stimulus applied is greater or less. The contraction of muscles is differ- ent, according to the purpose to be served by their contraction: thus, the heart contracts with a jerk; the urinary bladder, sloAvly and uniformly. The intensity of muscular contraction—that is, the degree of poAver Avith which they draAv themselves together— is regulated by the action of the brain: it is generally regulated by the will, according to certain limits, Avhich are different in dif- ferent individuals. A particular organization of the muscles, is favorable to the intensity of their contraction; this organization is, a considerable volume of fibers, strong, of a deep red, and striated transversely. The cerebral influence, and the disposition of the muscular tissue, are the two elements of the intensity of muscu- lar contraction. A very great cerebral energy is rarely found united in the same individual with that disposition of the muscular fibers Avhich is ne- cessary to produce intense contractions. These elements are al- most always in an inverse ratio. When they are united, they produce astonishing effects. Perhaps this union existed in the athlatse of antiquity ; in our times, it is observed in certain moun- tebanks. The muscular power may be carried to a wonderful de- gree, by the action of the brain alone; Ave know the strength of an enraged person, of maniacs, and of persons in convulsions. The will governs the duration of the contraction ; it cannot be carried beyond a certain length of time, hoAvever it may vary in different individuals. A feeling of weariness takes place, not very great at first, but which goes on increasing, until the muscle refuses con- traction. To prevent this inconvenience, the motions of the body are so calculated, that the muscles act in succession, the duration of each being but short. Our not being able to rest long in the same position is thus explained, as an attitude which causes the contraction of a small number of muscles, can be preserved but a very short time. The feeling of fatigue, occasioned by muscular contraction, soon goes off, and in a short time the muscles recover the power of contracting. The quickness of the contractions are, 414 PHYSIOLOGICAL. to a certain degree, subject to cerebral influence. Wc have a proof of this in our ordinary motions ; but beyond this degree, it depends evidently on habit. In respect of the rapidity of motion ; there is an immense dif- ference between that of a man, who touches a piano for the first time, and that Avhich the same man produces, after several veers' practice. There is, besides, a very great difference in persons, Avith regard to the quickness of contractions, either in ordinary motions, or those which depend on habit. As to the extent of the contractions, it is directed by the Avill: but it must necessarily de- pend on the length of the fibers ; long fibers having a greater ex- tent of contractions than those that are short. The will has gen- erally a great influence on the contraction of muscles; it is not, hoAvever, indispensible; in many circumstances, motion takes place, not only without participation of the will, but even contrary to it; Ave find very striking examples of this, in the effects of ha- bit, of the passions, and of diseases. CARTILAGE. Cartilage is a semi-pellucid substance, of a milk-Avhite or pear- ly color, entering into the composition of several parts of the body. It holds a middle rank, in point of firmness, between bones or hard parts, and the softer constituents of the human frame. It appears, on a superficial examination, to be homogeneous in its texture; for, when cut, the surface is uniform, and contains no visible cells, cavities nor pores, but resembles the section of a piece of glue. It possesses a very high degree of elasticity, which properly dis- tinguishes it from all other parts of the body. Hence it enters into the composition of parts, Avhose functions require the combi- nation of firmness Avith pliancy and flexibility; the preservation of a certain external form, with the power of yielding to external force or pressure. Anatomists divide cartilage into two kinds, the temporary and the permanent. The former are confined to the earlier stages of existence ; the latter commonly retain their cartilaginous structure BONE. 415 throughout life. The temporary cartilages are those inAvhich the bones are formed. All the bones, except the teeth, are formed in a nidus of cartilage. The permanent cartilages are of various kinds. They compose the external ear, and external aperture of the nostrils and eyelids. The larynx is formed entirely of this substance; and the trachea, or Avindpipe, with its branches, is fur- nished Avith cartilaginous hoops, by which these tubes are kept permanently open, for the ready passage of the air to and from the lungs. The bodies of the vertebra? are joined by large masses of a peculiar substance, partaking of the properties and appear- ance of cartilage and ligament, which alloAv of the motions of these parts on each other, without Aveakening the support that is afforded to the upper parts of the body in general, and to the head in particular, by the vertebral column. These cartilages impart great elasticity to the spine, by which the effects of concussion, from jumping, from fall, etc., are weakened and destroyed, before they can be propagated to the head. When the body has been long in an erect position, the compression of these cartilages, by the superior parts, diminishes the hight of the person. They re- cover their former length when freed from this pressure. Hence a person is taller when he rises in the morning, than after sus- taining the fatigues of the day; and the difference has sometimes amounted to an inch. Cartilages are sometimes interposed be- tAveen the articular surfaces of bones, Avhere they fill up irregulari- ties, that might otherwise impede the motions of the part, and in- crease the security of the joint, by adapting the articular surfaces to each other. These surfaces are, in every instance, covered by a thin crust of cartilage, having its surface most exquisitely polish- ed, by which all friction in the motions of the joint is avoided. BONE. The bones are the hardest and most solid parts of animals. They constitute the frame ; serve as points of attachment to the muscles, and afford support to the softer solids. They are the instru- ments, as muscles are the organs of motion. In the mammalia, 4i6 PHYSIOLOGICAL. birds, fish and reptiles, the whole system of bones, united by the vertebral column, is called the skeleton. In the foetus, they are first a vascular, gelatinous substance, in different points of Avhich, earthy matter is gradually deposited. This process is perceptible toAvards the end of the second month ; and, at the time of maturi- ty, the bone is completely formed. After birth, the bones become gradually more solid, and, in the temperate zone, reach their per- fection in men between the ages of fifteen and twenty, i rum this age, until fifty, they change but slightly; after that period, they groAV thinner, lighter, and more brittle. Those of the tAvo first classes of animals are harder on their exterior than they are inter- nally. Their material, except in the teeth, is nearly the same throughout. Their structure is vascular, and they are traversed by the blood-vessels, and the absorbents. They are hardest at the surface, Avhich is formed by a firm membrane, called the perios- teum; the internal parts are cellular, containing a substance called marrow. The use of the marroAv is to prevent the too great dry- ness and brittleness of the bones. Chimistry decomposes bone into gelatin, fat, cartilage, and earthy salts. A fresh bone boiled in water, or exposed to the action of an acid, gives out its gelatin. If boiled in Avater, on cooling the decoction, a jelly is formed, Avhich makes a good por- table soup. A pound of bone yields tAvice as much as the same quantity of fish. The earth of bones is obtained by calcination; that is, by exposing them to a red heat, by which they are de- prived of the soft substances. That part of anatomy Avhich treats of the bone, is called osteology. SPINE. Spine, (from spina, thorn, so called, from the shape of the pro- cesses of the vertebra?,) in anatomy, the vertebral or spinal column, the back-bone in common language, is the articulated bony pillar at the back of the trunk, forming the foundation or basis of sup- port and connection to all the other parts of the frame. It is placed perpendicularly in the body, supporting the head on its upper ex- SPINE. 417 tremity, while the lower end rests on the pelvis. The bones of the chest, to which the upper extremities are attached, are fixed to its sides, while the ossa innominata, or the great bones to which the lower limbs are articulated, are immovably united to it beloAV. It is the point of attachment and support in front for the viscera of the thorax and abdomen, and for the great trunks of the blood vessels. We may thus regard it as the central and most essential piece of the skeleton, as the center of motion for the head and limbs, and the basis of support for all the great internal organs. Again : the bones which compose it give attachment to the principal muscles moving the head, the shoulders, and the arms, to those which act on the trunk, and to some part of the abdominal muscles, and of those which move the lower limbs. Further, it constitutes a canal which receives and protects the spinal marroAv, and gives issue to the various nerves proceeding from that organ to the trunk and limbs. The importance of the spine is so great that it modifies all the details of the organization of the animals Avhich possess it. It is formed of twenty-nine pieces of bones strongly articulated into each other, and placed in succession, from above, downwards. The twenty-four upper ones are called vertebrae. Distortions of the spine are the unnatural inflections of the spine, which give a more or less deformed figure to the trunk, and even to the limbs ; hence wry neck, high shoulders, hump back, uneven hips, lameness, etc., are very frequent among the higher classes of our time, particularly among the females ; and, generally, owing to want of care or judgment in those Avho have charge of children, or to the injudicious habits of the persons afflicted, and frequently aggravated and made permanent by improper means used for reme- dying them. The beauty of the whole body depends chiefly upon the natural formation of the spine. This column of vertebra? ought not, permanently, to deviate from the straight line to the right or left; but it has, naturally, some slight curvatures forAvards and backAvards. In the region of the loins, it is bent a little forwards; in the region of the chest a little backwards; and at the neck, again, somewhat forward. This regular formation of the spine is produced by the character of the vertebra?, the cartilages which unite them, and the muscles of the back, which support and move them. If the vertebrae themselves suffer from disease, as, for in- 53 418 PHYSIOLOGICAL. stance, in case of rickets, the spine is not capable of supporting the head and keeping the body straight; it becomes curved, and, if remedies are not applied in season, this unnatural curvature in- creases daily, and permanent distortion at length takes place. If the cartilages and ligatures suffer relaxation, as in case of a debili- tated state of the body, the spine cannot, after every motion, re- sume its proper position ; and it may easily happen that some ver- tebra? become partially dislocated, and thus a disposition to distor- tion takes place, because the part of the spine over these vertebra? is deprived of its proper support, and must incline to one side. The muscles of the back, situated on both sides of the spine, equal in number and form, and destined, not only to execute the mani- fold movements of the trunk, but, also, to maintain, by the equili- brium of their power, the straight direction of the spine, frequently occasions distortions by losing their vigor; for the spine, in this case, wanting its natural support, inclines sideways or backwards. The same effect may be produced by too frequent, or too continu- ed, use of one set of muscles in a particular way; for the spine becomes, at last, permanently fixed in the posture which it has been compelled to assume during the exercise. This survey shows us the various causes of distortions, and the proper means for preventing them. The causes may be reduced to diseases and injudicious habits. The diseases of children, which may occasion distortions of the spine, are chiefly scrofula and rickets, so often connected with it, and general debility. These diseases may be best prevented by the use of food easily digestible, by pure air, hard bed, not too warm, frequent exercise, great cleanliness, frequent bathing, wash- ing, and rubbing the skin, and similar requisites of a good physical education. The muscles of the back are often debilitated by com- pelling children, particularly Aveakly ones, to sit up in a constrained posture, Avhich distresses the spine, and produces a sinking and bending, in search of relief, or by allowing children too little free movement and exercise, and obliging them, continually, to sit still and read, the surest mode of producing physical and intellectual cripples. The use of corsets also contributes much to the weak- ness of the dorsal muscles, and, consequently, to distortion of the spine. If the shoulders are continually supported, artificially, by a corset, the dorsal muscles, destined by nature to keep the spine SPINE. 419 straight, remain inactive, and lose their power; the body becomes unable to support itself without the corset, and a sinking and bend- ing take place as soon as it is removed. If to this is added the continual command, perhaps accompanied by threats, to sit straight, which has become actually impossible to the child, its exertions result in nothing but a curvature of the spine, Avhich is, therefore, so frequent in girls of the higher classes ; but, in boys of the same families, who are neither tormented with corsets, nor admonished so repeatedly to sit straight, is much rarer. The second cause of distortions, injudicious habits, deserves particular attention, be- cause much may be done to prevent them. The habit of many nurses to carry children always on the same arm, accustoms the child to incline always to one side, and to sleep in one position, from which a distortion of the spine naturally arises in the course of time. The bad position of the body in some amusements and occupations—for instance, the manner in which young people sit in writing, reading, drawing, sewing, embroider- ing, playing on the flute, violin, harp, and guitar; the habit of crossing the feet in standing, or of standing on one foot; the habit of lying crooked in bed; and even the habit of girls to spend a long time, in a constrained position, dressing their own hair, may occasion distortion of the spine. Every one-sided motion, often repeated, may produce a tendency to such distortion; and the ten- dency once existing, the evil increases every day. This distor- tion, besides disfiguring the body and unfitting the subject forcer- tain associations, also tends to produce inflammation of the lungs, dropsy of the chest, pulmonary consumption, and apoplexy—a general disturbance of the health, and early death. With women, it often gives rise to painful labors, and sometimes makes a natu- ral delivery impossible. The proper means of guarding against distortion we have already suggested in the directions respecting food, air, exercise, and cleanliness ; the prevention of ill habits on the part of nurses, and of the children themselves, and in the important rule not to com- pel a straight carriage of the body by the wearing of corsets, nor by the continual injunction to stand and sit straight, as both tend directly to produce the evil intended to be prevented. It is im- portant to detect a distortion of the spine as early as possible. It is, therefore, the duty of mothers and governesses to examine 420 PHYSIOLOGICAL. often the body of children. The child should be undressed and placed in such a way, (not lying doAvn,) that the Avhole position may be as easy as possible. Then the vertebra? must be struck slightly Avith the hand to discover if there is a prominence or a sensation of pain in any place. The examiner should then pro- ceed to the parts of the body on each side of the spine, Avhich ought to be perfectly equal. The neck, the shoulders, and the hips, are to be looked at: if the latter are uneven, the hip-joints and feet must be also tried. The examiner should also see whe- ther the breast bone is precisely in the middle of the breast, and whether it forms a straight line, whether the clavicles are uniform, whether the ribs lie even. With grown girls, the unevenness of the breasts often furnishes the earliest sign of distortion of the spine. These examinations ought to be made once or twice a week, and, in the case of girls, even after they have arrived at ma- turity, because the years immediately succeeding the period of pu- berty, are those in Avhich distortions are most frequently manifest- ed in the female sex, and because a cure can hardly be expected much after the twentieth year. Attention to distortion ought not to be delayed until a high shoulder or hip shoAvs itself; these are only proofs of a distortion which has already long existed. If, hoAvever, any thing like distortion is perceived, do not resort to the means, so often recommended, of suspension by the arms, or use of plasters, which can avail nothing; and do not expect that the dancing-master can remedy ihe evil, Avhich will only increase under his lessons. Assistance can be rendered only by a physi- cian familiar with these deformities, and Avho has made himself ac- quainted with the general state of body of his patient by a careful examination. The cure must not be expected too soon, and the orders of the physician must be scrupulously obeyed. Too much reliance is not to be placed on machines. JOINT. Joint, in general, denotes the juncture of two or more things. The joints of the human body are called, by anatomists, articula- tions. CHYME. 421 The suppleness to which the joints may be brought, by long practice, from the time of infancy, is very surprising. Every common posture-master shows us a great deal of this ; but one of the most Avonderful instances of it, was in a person of the name of Clark, and famous for it in London, Avhere he was commonly knoAvn by the name of Clark, the posture-master. This man had found the Avay, by long practice, to distort many of the bones, of which nobody before had ever thought it possible to alter the po- sition. He had such an absolute command of his muscles and joints, that he could almost disjoint his whole body; so that he once imposed on the famous Mullens, by his distortion, in such a manner, that he refused to undertake his cure ; but, to the amaze- ment of the physician, no sooner had he given over his patient, than he saw him restore himself to the figure and condition of a proper man, with no distortion about him. CHYME. Chyme. In animal economy, in the process of digestion, the food is subjected to a temperature usually above ninety degrees of Fahrenheit. It is mixed with the gastric juice ; a liquor secreted by the glands of the stomach, and is made to undergo a moderate and alternate pressure, by the contraction of the stomach itself. It is thus converted into a soft, uniform mass, of a grayish color, in which the previous texture or nature of the aliment can be no lon- ger distinguished. The chyme, as is termed this pulpy mass, in- to which the food in the stomach is resolved, passes by the pylo- rus into the intestinal canal, where it is mixed with the pancreatic juice and the bile, and is still exposed to the same temperature and alternating pressure. The thinner parts of it are absorbed by the slender tubes termed the lacteals. The liquor thus absorbed, is of a Avhite color; it passes through the glands of the mesentery, and is at length conveyed by the thoracic duct into the blood. This part of the process is termed chylification, and the white liquor thus formed, chyle. It is an opaque, milky fluid, mild to the taste. By standing for some time, one part of it coagulates ; another por- 422 PHYSIOLOGICAL. tion is coagulated by heat. The chyle, after mixing with the lymph conveyed by the absorbent vessels, is received into the blood, Avhich has returned from the extreme vessels, before this passes to the heart. All traces of it are very soon lost in the blood, as it mixes perfectly Avith that fluid. It is probable, however, that its nature is not at once completely altered. The blood passing from the heart, is conveyed to the lungs, Avhere it circulates over a very extensive surface presented to the atmospheric air ; with the intervention of a very thin membrane, which does not prevent their mutual action. During this circula- tion, the blood loses a considerable quantity of carbon: part of Avhich, it is probable, is derived from the imperfectly assimilated chyle; as this, originating in part from vegetable matter, must contain carbon in larger proportion than even the blood itself. LIVER. A large gland, Avhich occupies a considerable portion of the cavity of the belly, and which secretes the bile. It is a single organ of an irregular shape, brownish red color, and, in general, is smaller, in proportion, as the individual is more healthy. It occupies the right hypocondrium, or space included by the false ribs, and a part of the epigastric region, and lies immediately under the diaphragm, (midriff,) above the stomach, the transverse colon, and right kidney; in front of the vertebral column, the aorta, and the inferior vena cava; and behind the cartilaginous edge of the chest. The right false ribs are on its right, and the spleen on its left. The superior surface is convex, and the infe- rior is irregularly convex and concave, which has given rise to the division into the right or large lobe, the small or inferior lobe, and the left lobe. The right extremity of the liver is lower than the left, and is the most bulky part of the organ. The pressure of the surrounding organs, and certain folds of the peritoneum, called its ligaments, which connect it with the diaphragm, retain the liver in its place, leaving it, at the same time, a considerable pow- er of changing its relative position. BILE. 423 The organization of the liver is very complicated. Besides its peculiar tissue, or parenchyma, the texture of which is unknoAvn, it receives a larger number of vessels than any other gland. A peculiar venous system, that of the- vena portarum, is distributed in it. To this must be added, the ramifications of the hepatic artery and veins, the nerves which are small, the lymphatic ves- sels, the excretory tubes, and a peculiar tissue, enclosed by a double membrane, a serous or peritoneal, and cellular one. The excretory apparatus of the bile is composed of the hepatic duct, which, rising immediately from the liver, unites with the cystic duct, which terminates in the gall bladder. The choledochic duct is formed by the union of the two preceding, and terminates in the duodenum. BILE. A yellowish-green liquid substance, of a bitter taste. Man, and many animals have, on the inferior surface of the liver, a peculiar bladder, in which the bile, formed by the liver from the blood, is preserved. It consists of water, and several other sub- stances. The water constitutes the greatest part, and keeps the other parts in a state of solution. The remaining ingredients are a yellow, very bitter, fusible resin, which contributes most to the taste of the bile; a small portion of natron; some mineral alkaline salts; some oxygen of iron; a small quantity of a yellowish sub- stance, Avhich is only partly dissolved in the natron; and a con- siderable portion of albumen. Thenard and Berzelius have done much to determine the ingredients of the bile. Its principal use seems to be, to separate the excrement from the chyle, after both have been formed, and to produce the evacu- ation of the excrements from the body. It is probable that these substances Avould remain mixed together; and they would, per- haps, even be partially absorbed together, were it not for the bile, which seems to combine with the excrements, and, by this com- bination, to facilitate its separation from the chyle, and thus to prevent its absorption. Fourcroy supposes that the bile, as soon 424 PHYSIOLOGICAL. as it is mixed with the contents of the intestinal canal, suffers a decomposition; that its alkali and saline ingredients combine with the chyle, and render it more liquid, Avhile its albumen and resin combine with the excrementitious matters, and gradually render them less fluid. From the late experiments of Berzelius, on fceces, it cannot be doubted that the constituents of the bile are to be found in the excrementitious matter; so that the ingenious theory of Fourcroy is so far probable. The bile also stimulates the intestinal canal, and causes it to evacuate its contents sooner than it othenvise Avould do; for Avhen there is a deficiency of bile, the body is constantly costive. Biliary calculi, or gall-stones, are sometimes found in the gall-bladders of men and animals. They are more rarely met Avith in the substances and body of the liver. Those that are found in the human subject consists, principally, of that peculiar substance called, by Fourcroy, adipocire. They are of a Avhite, grayish-broAvn, or black color. The calculi found in the gall-bladders of quadrupeds, have been thought to consist almost entirely of inspissated bile; but, though much less compli- cated than the corresponding concretions in the human subject, they must contain something more than the inspissated fluid, since they are insoluble, both in alcohol and water. BLOOD. Blood is the red fluid contained in the blood-vessels of animal bodies. It is found in the mammalia, in birds, in reptiles, and in fishes. In the last tAvo classes of animals, the temperature of the blood is much loAver than in the former, for Avhich reason they are distinguished by the name cold-blooded, while the others are term- ed warm-blooded animals. Insects and Avorms, instead of red blood, have a juice of a whitish color, which is called white blood. In the blood are tAvo different substances, which are separated by coagulation'—the serum, a fluid like the white of an egg, and a thick matter, to Avhich the red color properly belongs, which is much heavier than the former, and is called the coagulum. The last may be divided again into two different parts; viz: into the BLOOD. 425 cruor, or that part of the blood which is intrinsically red and co- agulable, and lymph, or fibrine, to Avhich the coagulation of the blood must be ascribed. The fibrine, in young animals, is much Avhiter than in older and stronger ones. The blood of the latter contains much more azote than that of the former. If the nourish- ment of animals be changed, we also find an alteration in the con- stituent parts of their blood. It is also changed by diseases. In animals that are hunted to death, or killed by lightning, the blood does not coagulate. The blood of birds is more highly colored, and warmer, than that of viviparous animals, and coagulates more easily in the air. That of reptiles, and fishes, coagulates Avith dif- ficulty. Aided by magnifying glasses of a strong power, one may observe, in examining the blood of the living animal, or in blood which is newly drawn, that it consists, especially the cruor, of little globular bubbles, the globules of the blood, as they are call- ed, the diameter of which amounts to about the three hundredth part of a line. In blood that has been drawn some time, although this time may be very short, they are not to be discovered. They are the effect of the life that pervades the blood. The more ro- bust and healthy an animal is, the more globules are perceived. They show, as it were, the transition from the formless liquid to the original form of the first organized matter. The blood is of the greatest importance to the life of an animal, and may be considered as the source of life. As long as the body is living, the blood is in perpetual motion. When it is taken out of the body, a remarkable change soon follows: it begins to co- agulate, and then undergoes, first an acetous, and, after a few days, a putrid fermentation. All the blood takes its origin from the chyle, and deposits, by degrees, the nourishing particles re- quisite to the preservation and growth of the body, by a multitude of vessels adapted thereto. This is done while it is passing from the heart into the remotest parts of the body, and from thence back. The circulation of the blood is, as it were, the principle, and first condition of life. In its absence, except in cases of faint- ing, suffocation, etc., life ceases. The heart, the center of the circulation of the blood, has a two-fold motion, of contraction and dilatation, which constantly alternate. With the heart, two kinds of vessels are connected—the arteries, and the veins. The circu- lation of the blood proceeds with an astonishing rapidity: did it 54 426 PHYSIOLOGICAL. floAv at an equal rate in a straight line, it would run, in the space of one minute, through 149 feet. This swiftness, however, exists only in the larger vessels near the heart; the farther the blood re- cedes from the heart, the sloAver its motion becomes. In a groAvn up person, in good health, Ave may reckon the mass of blood at from twenty-four to thirty pounds. Blood-vessels are the tubes or vessels in Avhich the blood cir- culates. They are divided into tAvo classes,—arteries, and veins,-— which have tAvo points of union, or connection: the first, in the heart, from Avhich they both originate; and the other in the mi- nute vessels, or net-Avork, in Avhich they terminate. The arteries arise from the heart, and convey the blood to all parts of the body; the veins return it to the heart. The arteries distribute throughout the body a pure, red blood, for the purpose of nourishment; Avhile the veins return to the heart a dark-colored blood, more or less loaded with impurities, and deprived of some of its valuable pro- perties. But this is not returned again to the body in the same state. For the heart is Avisely divided into tAvo portions, or sides, a right and left, one of Avhich receives the impure blood from the veins, and sends it to the lungs, to be defecated and freshly sup- plied with oxygen, or vital air; Avhile the other receives the pure red blood from the lungs, and circulates it aneAV through the arte- ries. The arteries arise from the left ventricle of the heart, by one large trunk, nearly an inch in diameter, which is gradually subdivided into smaller ones, as it proceeds towards the limbs, till they terminate, at last, in vessels so small as to be almost invisi- ble, and in a fine net-Avork of cells, extending through the Avhole body, into Avhich the blood is poured out, and nutrition, or the in- crease of the body, takes place, and from which the residue is taken up by the small veins, to be returned to the heart. The arteries and veins are widely different in their structure, as well as their uses. The former are composed of very strong, firm, elastic coats, or membranes, Avhich are four in number. The external covering, and the internal lining of the arteries, although belonging to different classes of membranes, are both very thin and soft. The second coat is very thick, tough, and elastic, being that Avhich chiefly gives their peculiar appearance to the arteries. The third is formed of fibers, apparently muscular, arranged in circular rings around the tube of the vessels. It is well known BLOOD. 427 that the pulse of the heart is felt in the arteries alone, although, in the bleeding of a vein, we sometimes see the blood start as if in unison with the beating of the heart. The pulse is produced by the wave, or stream of blood, which is driven by the heart through the arteries, distending, and slightly elevating them; after which they instantly contract, from their elasticity, and thus force the blood into the smaller vessels; The pulse varies in its character, with the general state of the health. When arteries are cut, or wounded, the firmness of their coats prevents their closing; and hence arises the fatal nature of wounds of large vessels, which will remain open till they are tied up, or till death is produced. The veins commence in small capillary tubes, in every part of the body, and by their gradual union, form large trunks, till they at last terminate in two, which pour their contents into the heart. Their structure is much less firm than that of the arteries. They are very thin and soft, consisting of only two thin coats, or mem- branes. The inner, or lining membrane, is frequently doubled into folds, forming valves, Avhich nearly elose the passage in the veins, and thus give very material support to the blood as it is moving up in them towards the heart. These valves are not found in the veins of the bowels, the lungs, or the head. The number of the veins is much greater than that of the arteries, an artery being often accompanied by two veins. They differ, also, in this: that while the arteries are deeply seated in the flesh, to guard them from injury, the veins are very frequently superficial, and covered only by the skin. The veins, it is Avell knoAvn, are the vessels commonly opened in blood-letting, although, in cases which ren- der it necessary, a small artery is sometimes divided. There are two portions of the venous system, which do not correspond ex- actly Avith our general description; these are, the veins of the bowels and of the lungs. The former circulate their blood through the liver, before it returns to the heart; and the latter, the pulmo- nary veins, convey red blood from the lungs to the heart. It should also be mentioned, that the large vein, which brings back the blood from the lower parts of the body, receives from the lympha- tic and lacteal vessels the chyle from the boAvels, Avhich supplies the waste of the blood and nourishes the body, and the serous and other Avatery fluids Avhich are taken up by the absorbents in all parts of the body. 42b PHYSIOLOGICAL. KIDNEY. Kidney, one of the abdominal viscera, consisting of two volu- minous glands, the office of which is to secrete the urine from the blood. One of these glands lie on the right, and the other on the left of the vertebral column, or back-bone. They are both con- tained in a fatty, cellular substance, (suet,) and are situated behind the peritonaeum, and before the diaphragm and the quadratus lum- borum. They are penetrated Avith blood-vessels and nerves ; are of a reddish color, and more consistent than the other glands. An external cellular membrane, and an internal fibrous membrane en- velope each kidney, Avhich is divided into the cortical substance, and the tubulous substance. The former constitutes the exterior part of the kidney, and extends betAveen the cones formed by the latter. It secretes the urine; that is, separates its elements from the blood, and combines them, Avhile the latter pours it into the pelvis, a membranous bag situated at the middle of the kidney, from which it is conveyed by the ureter, a membranous tube, into the bladder. From the bladder, the urine is evacuated by the urethra, a membranous canal passing through the penis. The kidneys are not mere filters or sieves, as Avas anciently supposed, and as some modern physiologists have maintained; they are true glands ; that is, a vascular nervous apparatus, hav- ing a particular action, for the production of a particular fluid. The kidneys are subject to an inflammation, called nephritis, and to a nervous pain, called nephralgia. The kidney sometimes con- tains stones, gravel or sand in the pelvis, and also in the cortical and tubulous substance, which occasion the most excrutiating pain. Diseases of the kidneys are generally occasioned by excess in eating and drinking, particularly in subjects addicted to venery, or accustomed to violent riding, or much walking. Temperance, vegetable diet, warm bathing, abstinence from equitation, etc., are preventives. INTESTINE. 429 SPLEEN. Spleen, or milt: a spongy viscus, varying much in form and size, situated on the left side, between the eleventh and twelfth false ribs, and covered with a simple, firm membrane, arising from the peritona?um. It is of an oval form, and about one-fifth smaller than the liver. Its upper surface is connected with the diaphragm, and its interior with the stomach. It is convex to- wards the ribs, and concave internally, and of a livid color. The splenic artery is very large, in proportion to the size of the organ, and is divided into numerous small branches, penetrating the sub- stance of the spleen. The splenic vein is larger than the artery, in the proportion of five to one; and, by its junction with the mesenteric, constitutes the trunk of the vena portae, which car- ries the blood into the substance of the liver. From this splenic artery, several branches called vasa brevia, go off to the stomach, which they supply with blood. The uses of the spleen are entirely unknown; but they appear to have some connection with the process of digestion. The spleen is subject to inflammation, {splentis,) and, as often hap- pens after agues, the inflammation becomes chronic; the tumor is then commonly called the ague cake, though that name is also given to a tumor of the liver, succeeding intermittents. It is also, in some cases, too feeble in its action, and then the digestion suf- fers. Spleen is also sometimes used to signify the hypochondri- asis. INTESTINE. Intestine, (intestinum, from intus, within.) The convoluted membranous tube, that extends from the stomach to the anus, re- ceives the ingested food, retains it a certain time, mixes with it the bile and pancreatic juice, propels the chyle into the lacteals, and covers the foeces with mucus, is so called. The intestines are situated in the cavity of the abdomen, and 430 PHYSIOLOGICAL. are divided into the small and large, which have, besides their size, other circumstances of distinction. The small intestines are supplied internally with folds, called valvule conniventes, and have no bands on their external surface, The large intestines have no folds internally; are supplied externally with three strong muscular bands, Avhich run parallel upon the surface, and give the intestines a saccated appearance; they have also small fatty ap- pendages, called appendiculse epiploicse. The first portion of the intestinal tube, for about the extent of twelve fingers' breadth, is called the duodenum; it lies in the epigastric region, makes three turnings, and, betAveen the first and second flexure, receives, by a common opening, the pancreatic duct, and the ductus communis choledochus. It is in this portion of the intestines, that chylifica- tion is chiefly performed. The remaining portion of the small intestines is distinguished by an imaginary division into the jeju- num and ileum. The jejunum, which commences Avhere the duodenum ends, is situated in the umbilical region, and is mostly found empty; hence its name: it is everyAvhere covered with red vessels, and, about an hour and a half after a meal, Avith distended lacteals. The ileum occupies the hypogastric region and the pel- vis, is of a more pallid color than the former, and terminates by a transverse opening into the large intestines, Avhich is called the valve of the ileum, valve of the ca?cum, or the valve of the tulipius. The beginning of the large intestines is firmly tied down in the right iliac region, and, for the extent of about four fingers' breadth, is called the caecum, having adhering to it a worm-like process, called the processus cseci vermiformis, or appendicula caeci ver- miformis. The great intestine then takes the name of colon, ascends toAvards the liver, passes across the abdomen, under the stomach to the left side, where it is contorted like the letter S, and descends to the pelvis; hence it is divided, in this course, into the ascending portion, the transverse arch, and the sigmoid flexure. When it has reached the pelvis, it is called the rectum, from whence it proceeds, in a straight line, to the anus. The intestinal canal is composed of three membranes, or coats; a common one from the peritoneum, a muscular coat, and a vil- ous coat, the villi being formed of the fine terminations of the arteries and nerves, and the origins of lacteals and lymphatics. The intestines are connected to the body by the mesentery; the DIAPHRAGM. 431 duodenum has also a peculiar connecting cellular substance, as have likewise the colon and rectum, by whose means the former is firmly accreted to the back, the colon to the kidneys, and the latter to the os coccygis, and, in women, to the vagina. The re- maining portion of the tube is loose in the cavity of the abdomen. The arteries of this canal are branches of the superior and inferior mesenteric, and the duodenal. The veins evacuate their blood into the vena porta?. The nerves are branches of the eight pair and intercostals. The lacteal vessels, which originate principally from the jejunum, proceed to the glands in the mesentery. DIAPHRAGM. Diaphragm, in anatomy, a large, robust, muscular membrane or skin, placed transversely in the trunk, and dividing the chest from the belly. In its natural situation, the diaphragm is convex on the upper side towards the breast, and concave on its loAver side towards the belly ; therefore, when its fibers swell and con- tract, it must become plain on each side ; and consequently, the cavity of the breast is enlarged, to give liberty to the lungs to re- cieve air in inspiration ; and the stomach and intestines are pressed for the distribution of their contents ; hence the use of this mus- cle is very considerable. It is the principal agent in respiration, particularly in inspira- tion ; for, Avhen it is in action, the cavity of the chest is enlarged, particularly at the sides, where the lungs are chiefly situated; and, as the lungs must always be contiguous to the inside of the chest and upper side of the diaphragm, the air rushes into them, in order to fill up the increased space. In expiration it is relaxed, and pushed up by the pressure of the abdominal muscles upon the viscera of the abdomen; and, at the same time that they press it upAvards, they pull doAvn the ribs, by Avhich the cavity of the chest is diminished, and the air suddenly pushed out of the lungs. 432 PHYSIOLOGICAL. PELVIS. Pelvis ; the loAver part of the cavity of the abdomen in men and animals. In the infant, it consists of many pieces ; but in the adult it is composed of four bones, so united, as not to admit of motion on each other, and is open above and beloAV; Avide at its upper part, and contracted at its inferior aperture. The out- side is roundish: the upper part broader; the loAver, narroAver. The Avhole pelvis is movable upon the thighs; the hip-bone is therefore raised, in Avalking, on that side Avhich is supported by the thigh; on the contrary, it sinks immediately Avith the trunk on that side upon Avhich the foot is raised and advanced. The walls of the cavity of the pelvis, are even, smooth, and covered Avith flesh. A line drawn through the middle of the pelvis, di- vides it into two parts, one of Avhich is called the upper or larger, and the other, the lower or smaller one. In Avell-formed persons of a middle size, the diameter of the great pelvis, or the distance of one hip-bone to the other, is in the male sex about nine, in the female about eleven inches. The superior size of the female pel- vis, is intended to assist gestation and parturition. It is evident that the pelvis of men must have, on account of their erect figure, a different direction from that of animals. The pelvis contains a part of the small intestines, the rectum, the bladder, the internal organs of generation, the large nerves, and blood-vessels of the loAver limbs, and many absorbent vessels, Avith their glands. Its office is to give steadiness to the trunk; to connect it Avith the lower extremities, by a safe and firm junction ; to form the center of all the motions of the body, and to give support to the gravid uterus. UTERUS. Uterus, (the womb:) the organ in which the embryo is recei- ved from the ovary, to which it becomes adherent so as to receive the materials of its growth, and in which it is restrained, for a UTERUS. 433 longer or a shorter time, in various species, exist until its expul- sion in the process of parturition. A proper uterus belongs only to the mammalia: oviparous gene- ration, under various modifications, if found in the other classes ; and the female organ is, therefore, reduced to a mere canal (ove- duct) for the transmission of the ova. In the human female, the uterus is a spongy receptacle, resembling a compressed pear, situ- ated in the cavity of the pelvis, above the vagina, and between the urinary bladder and rectum. Its form resembles that of an oblong pear flattened, with the depressed sides placed toAvards the ossa pubis and sacrum ; but, in the impregnated state, it becomes more oval according to the degree of its distension. For the convenience of description, and for some practical purposes, the uterus is dis- tinguished into three parts: the upper part called the fundus; the loAver, the servex; the space below them, the body. The uterus is about three inches in length, about tAvo in breadth, at the fundus, and one at the cervex. Its thickness is different at the fundus and cervex, being, at the former, usually rather less than half an inch, and, at the latter, somewhat more; and this thick- ness is preserved throughout pregnancy, chiefly by the enlarge- ment of the veins and lymphatics, there being a smaller size of the arteries; but there is so great a variety, in size and dimensions, of the uterus in different women, independent of the state of vir- ginity, marriage, or pregnancy, as to prevent any very accurate mensuration. The internal surface of the uterus is corrugated in a beautiful manner; but the rugue or wrinkles, which are longitu- dinal, lessen as they advance into the uterus, the fundus of which is smooth. In the intervals betweeu the rugue are small orifices like those in the vagina, which discharge a mucus, serving, be- sides, other purposes, that of closing the os uteri very curiously and perfectly during pregnancy. The substance of uterus, which is very firm, is composed of arteries, veins, lymphatics, nerves, and muscular fibers, curiously interwoven and connected together by cellular membranes. The use of the Avomb is for menstruation, conception, nutrition of the foetus, and parturition. It is liable to many diseases, the principal of which are retroversion and falling down, hydatids, dropsy of the uterus, moles, polypus, ulceration, cancer, etc. 55 434 PHYSIOLOGICAL. EMBRYO. Embryo ; the first rudiments of the animal in the Avomb, before the several members are distinctly formed, after which it is called the foetus. The time necessary to produce this is different in different species. The human embryo is visible in three Aveeks: at the end of four, a pulsation is perceptible, which is known to be the beating of the heart. It is now about the size of an ant or fly, and retains its transparency, which, hoAvever, gradu- ally diminishes, and, at the end of tAvo months, disappears; the eyes, nose, mouth, ears, and all the members, are distinguishable ; it is as large as a bee. In three months, every thing becomes more distinct; the sex becomes evident, and the foetus grows until it is ushered into the world as a child. OVARY. The ovaria are two flat oval bodies, about one inch in length, and rather more than half in breadth and thickness, suspended in the broad ligaments about the distance of one inch from the uterus behind, and a little below the fallopian tubes. They include a number of vesicles or ova, to the amount of twelve to tAventy, of different sizes, joined to the internal surface of the ovaria by cel- lular threads or pedicles, and contain a fluid which has the ap- pearance of thin lymph. The ovaria prepare Avhatever the female supplies towards the formation of the fcetus : this is proved by the operation of spaying, which consists in the extirpation of the ovaria; after which the animal not only loses the poAver of con- ceiving, but desire is forever extinguished. These vesicles have been generally regarded as little eggs Avhich detach themselves from the ovary after fecundation, and are carried into the cavity of the womb by the fallopian tubes. PART IV. MISCELLANEOUS. CHAP. I. CHIMISTRY. By this name, the etymology of which is uncertain, we under- stand the science Avhich teaches the nature of bodies, or rather the mutual agencies of the elements Avhereof they are composed, Avith a vieAV to determine the nature, proportions, and mode of combination of these elements, in all bodies. Natural Philoso- phy, or physics, examines the reciprocal influence of matter, in masses. Chimistry treats of the mutual action of the integrant parts. In the former, the phenomena are produced by the gene- ral attraction or repulsion of bodies ; in the latter, by minute com- bination or decomposition. With our present knowledge of mat- ter, and its laws, Ave cannot separate physics entirely from chi- mistry : one science cannot be studied without the other. Those artisans who first discovered the means of melting, combining and moulding metals ; those physicians who first extracted vegetable substances from plants, and observed their properties, Avere the first chimists. Instead, however, of observing a philosophical method in their examinations; instead of passing from what was known, to what was unknoAvn, early inquirers suffered themselves to be led astray by astrological dreams, the fables of the philoso- 436 MISCELLANEOUS. pher's stone, and a hundred other absurdities. Until the year 1650, Ave find little Avorthy of notice in the history of chimistry. Rhazis, Roger Bacon, Arnaud de Yilleneuve, Basilius Valentin, Paracelsus, Agricola, etc., observed some of the properties of iron, quicksilver, antimony, ammoniac and saltpetre. They discover- ed sulphuric, nitric, and other acids; the mode of rectifying spirits; preparing opium, jalap, etc., and of purifying the alkalies. Glau- ber Avas distinguished for the accuracy of his observations. He endeavored to improve certain instruments; advised operators not to throAv away, as useless, any residuum in performing expe- riments ; discovered the salt Avhich is called, from him, Glauber's salts, etc. Such isolated discoveries, hoAvever, could not form a complete science. Stahl appeared, and, although his theory Avas unsatis- factory and entirely gratuitous; and, as later observations have proved, erroneous; yet he laid the foundations of a regular sci- ence. He Avas himself much indebted to the celebrated Becher, whose vieAvs he corrected and expanded. He was sensible that the greater part of chimical phenomena might depend on a general cause, or, at least, on a few general principles, to which all com- binations must necessarily be referred. He supposed that bodies contained a combustible element, which inflammable bodies lost by being burned, and which they could regain from other bodies more inflammable. This element he called phlogiston. The establishing of a hypothesis, which connected almost all pheno- mena with each other, was an important step. Boerhaave adopt- ed Stahl's system, and contributed much to its general diffusion. He is the founder of philosophical chimistry, Avhich he enriched with numerous experiments respecting fire, the caloric of light, etc. Although the principles on Avhich these philosophers pro- ceeded Avere false, yet the science Avas much advanced by their labors. It Avas reserved for Black, Priestley, Cavendish and La- voisier, to overturn Stahl's system, and substitute the pneumatic, or antiphlogistic theory, the best history of Avhich is to be found in Fourcroy's Philosophic Chimique, and his Systeme des ~Con- noissances Chimiques. As soon as the composition of the atmospheric air was known, it was observed that combustible bodies, burning in contact Avith it, instead of losing one of their elements, absorbed one of the CHIMISTRY. 337 component parts of the atmosphere, and Avere thug increased in weight. This component part has received the name of oxygen, because many of the combustible bodies are changed by its ab- sorption into acids. Oxygen now took the place of phlogiston, and explained the difficulties which beset the phlogistic theory. Light and unity were introduced into chimistry by the new tech- nical nomenclature adopted in 1787, through the aid of which all the individual facts are easily retained in the memory, since the name of each body is expressive either of its composition or of its characteristic property. Twelve or fifteen terms have been found sufficient for creating a methodical language, in which there is no inexpressive term, and which, by changing the final syllables of certain names, indicates the change which takes place in the composition of bodies. Lavoiseur, Fourcroy, Guyton de Mor- Areau, and Berthollet, were the authors of this felicitous innovation. The chimical terminalogy admits of nothing arbitrary, and is adapted not only to express phenomena now known, but also any Avhich may be hereafter discovered. It furnishes the first exam- ple of a systematic and analytic language. The commencement of the nineteenth century forms a brilliant era in the progress of chimistry. The galvanic apparatus of Volta presented to the experimenter an agent unequaled in the variety, extent, and energy of its action upon common matter. With this apparatus, Sir Humphrey Davy commenced a series of researches, Avhich resulted in a greater modification of the science than it had ever before experienced. He proved that the fixed alkalies were composed of oxygen with metallic bases, and thus led the Avay to the discovery of an analogous constitution in the alkaline earths. To the same individual the science is principally indebted for the establishment of the simple nature of chlorine, and for the inves- tigation of iodine. His researches concerning the nature of flame, resulting as they did in the invention of the miner's safety-lamp, afforded to mankind a neAV demonstration of the utility of philo- sophy in contributing to the improvement of the arts of life. But that department of chimistry, which has of late been most suc- cessfully investigated, relates to the definite proportions in which bodies unite to form the various chimical compounds. To esta- blish the conclusions Avhich have been arrived at, a multitude of exact analyses were requisite. These Avere accomplished princi- ■138 MISCELLANEOUS. pally through the labors of Vauquelin, Gay Lussac, Thonard, Berzelius, and Thompson; and have terminated in the establish- ment of the general truth, that Avhen bodies combine chimically and intimately with each other, they combine in determinate quan- tities ; and that, Avheii one body unites Avith another in more than one proportion, the ratio of the increase may be expressed by some simple multiple of the first proportion. Upon this general fact, Doctor Wollaston constructed the logametric scale of chimical equivalents—an invention which has contributed, in an eminent degree, to render our knowledge of the constitution of compounds precise, by introducing the sure basis of arithmetical relations, Avhich, Avhen fixed with accuracy, are not susceptible of change. The doctrine of definite proportions may, therefore, be regarded as having communicated to the principles of chimistry that cer- tainty Avhich has long been considered as peculiar to the mathe- matical sciences; and it is in the development of these important relations, that the advancement of the science has been most con- spicuous. Among the still more recent improvements in chimis- try, may be cited the discovery of Dobereinere, relating to the power of platinum in effecting the combination of oxygen and hydrogen; the researches of Faraday, in Avhich many of the gases have been reduced to the liquid form; the discovery of neAv com- pounds of carbon and hydrogen, and the singular fact, which they exhibit, of different combinations being established in the same proportions; the elucidation of the new compounds of chlorine Avith carbon; of the peroxide of chlorine; the hydriodide of car- bon ; the perchloric, iodous, fulminic, and other acids; the disco- very of the real bases of silex and zircon, and that of the neAv principle, brome: add to these, that our knowledge of light and electricity has been greatly enlarged, and that the phenomena of electrc-magnetism are altogether neAv, and it becomes strikingly obvious that chimistry is still a progressive science. " Nor can any limits be placed to the extent of its investigations. Its ana- lysis is indefinite; its completion will have been attained only when the real elements of bodies shall have been detected, and all their modifications traced: but hoAV remote this may be from its present state, we cannot judge. Nor can Ave, from our present knowledge, form any just conception of the stages of discovery through which it has yet to pass." CHIMISTRY. 439 Chimistry has two ways of becoming acquainted Avith the in- ternal structure of bodies, analysis and synthesis. By the for- mer, it separates the component parts of a compound body; by the latter, it combines the separated element, so as to form anew the decomposed body, and to prove the correctness of the former process. These methods depend on a complete knowledge of the tAvo powers, by which all bodies in nature are set in motion, viz., attraction and repulsion. Attempts have been made to distinguish the attraction of elementary particles from planetary attraction— the former being designated a chimical affinity. But nature has only one controlling principle of attraction. The alternate play of attraction and repulsion, produces a great number of sensible phenomena, and a multitude of combinations, which change the nature and properties of bodies. The study of these phenomena, and the knowledge of these combinations, appertain to the depart- ment of chimistry. The history of a body must always precede its analysis. The mere examination of its form, its color, its weight, and the place where it was found, etc., is often sufficient, by a comparison, to lead to a knowledge of its chimical proper- ties. There is no science more extensive than chimistry, nor is it possible for one person to embrace it in its whole compass. To facilitate its study, it is considered in different points of vieAV, and thrown into divisions and subdivisions, so that a person may de- vote himself to one department of it, although the method of ob- serving, analyzing, and combining is the same in all; and although all the phenomena must be explained by the general theory, and referred to certain laAvs, of which a previous knowledge is requi- site. These laAvs constitute what is called philosophical chimis- try, Avhich explains what is meant by the affinity of aggregation or cohesion, by the affinity of composition, or chimical affinity. It treats of the phenomena of solution, saturation, crystalization, ebullition, fusion, nutralization. Chimical processes, by chang- ing or modifying the properties of bodies, suggest to the observer important considerations on the changes of form, density, and temperature. Philosophical chimistry weighs these considera- tions. It shows, further, that affinity may be exerted, 1st, be- tween two simple bodies; 2d, between a simple and a compound one; 3d, between compound bodies; and, establishing the princi- 440 MISCELLANEOUS. pie, that the same body has not the same affinity for all others, but attracts them unequally, it shows us the laAvs which deter- mine this preference, and the circumstances which modify it; such as cohesion, mass, insolubility, elasticity, and temperature. It measures the degree of affinity, Avhether of simple or compound bodies. It observes the circumstances Avhich aid or obstruct the play of attraction, and shoAvs that tAvo bodies Avill not act upon each other, unless one of them, at least, is in a fluid state; that bodies, even in a state of solution, act upon each other only at imperceptible distances ; that two bodies which have no percepti- ble affinity, may be made to combine, by the interposition of a third; and, finally, that the peculiar properties of bodies are des- troyed by their combination, and that the compound possesses continually new properties. Proceeding from these principles to the examination of bodies themselves, philosophical chimistry considers the effects of light, heat and electricity; the nature of the simple and compound inflammable bodies; of air and water; the composition and decomposition of acids; the nature and pro- perties of the salts; their relation to the acids; the calcination, solution, and alloying of metals; the composition and nature of plants; the characteristics of the immediate elements of vegetable substances; the phenomena of animalization; the properties of animal compound; and the decay of organic substances. This is the sphere of philosophical chimistry, while it confines itself to general views. According to the application of these general vieAvs, chimistry is divided into seven or eight branches, Avhich we have yet briefly to survey. The study of the great phenomena which are observed in the atmosphere, and Avhich are called meteors, constitutes mete- orological chimistry. This explains the formation of the clouds, rain, mist, snow, Avater-spouts ; the state of the atmosphere in re- lation to the hygrometer, barometer, and thermometer; the nature of the aurora borealis, and meteoric stones ; in short, all the chimi- cal processes going on above the surface of the earth. Geological chimistry treats principally of great combinations of nature which produce volcanoes, veins of metals, beds of mine- ral coal, basalt, mineral Avaters, the enormous masses of salt and lime, the saltpetre in the bed of the Indies, the natron of the lakes of Egypt, the borax of the lakes of Thibet. The geological chi- CHIMISTRY. 441 mist endeavors to discover and explain the causes of deluges, earth- quakes, the decrease of the Avaters on the globe, the ^influence of climate on the color of animals and plants, on the smell of'floAvers and the tastes of fruits. In these general views, he needs the aid of natural philosophy and physic. Chimistry, in its application to natural history, is divided in the same manner. There is a chimistry of the mineral kingdom which comprises metallurgy and assaying, and the examinations of all inorganic substances, as stones, salts, metals, bitumen, Avaters, a chimistry of the vegetable kingdom which analyzes plants and their immediate products ; and a chimistry of the animal kingdom, Avhich studies all substances derived from living or dead animals. This last is subdivided into physiological chimistry, which considers the changes produced in animal substances by the operation of life ; pathological chimistry, which traces the changes produced by dis- ease or organic defects; therapeutic or pharmaceutic chimistry, which traces the nature and preparation of medicines, shows the means of preserving them, and exposes the pretensions of empirics ; hygclic chimistry, Avhich acquaints us Avith the means of con- structing and arranging our habitations so as to render them heal- thy, of examining the air which we must breathe in them, guard- ing against contagious diseases, choosing wholesome food, dis- covering the influence of occupation, fashion, and custom, on the health. Agricultural chimistry treats of uie nature of plants and soils, and the laws of production. Sir Humphrey Davy first gave it the character of a science. It treats : first, of the general powers of matter Avhich have any influence on vegetation, of gravity, cohe- sion, chimical affinity, heat, light, electricity, the elements of mat- ter, especially such as are found in vegetables, and the laws of their composition and arrangements; second, of the organization of plants—their structure, the chimical composition of their organs, and the substance found in them, etc.; third, of soils ; fourth, of the nature of manure. Chimistry, finally, exerts an influence on the economy of do- mestic life, and on the arts. It simplifies and regulates the daily offices of the house-keeper; renders our dwellings healthy, Avarm, light; assists us in preparing clothing, food, drink, etc.: it teaches the best way of making bread; preparing and purifying oils ; of 56 442 MISCELLANEOUS. constructing bake-houses, ovens, and hearths; of bleaching and washing all kinds of stuff; of producing artificial cold, etc. The application of chimistry to the arts and manufactures is, hoAvever, still more important and extensive. Here its aim is to discover, improve, extend, perfect, and simplify the processes by Avhich the objects to be prepared may be adapted to our Avants. We close our remarks Avith the observation that a knoAvledge of chimistry may frequently be useful in judicial proceedings by bringing crime to light in cases of poisoning, counterfeiting coins, and written documents, etc. Chimical Classification and Nomenclature.—The chimist finds a small number of bodies, from Avhich only one kind of mat- ter can be obtained, in the present state of his knoAvledge, and by the instruments and agents Avhich he now has at his disposal. On the other hand, there is a large number of bodies from which he obtains several kinds of matter. The former, he calls elementary ox simple bodies; the latter, compound bodies. The number of simple bodies noAV knoAvn is fifty-three; that of the com- pound bodies is much greater, and might, at first, appear to be in- finite, since not only a difference of elements, but even a difference of the proportions in Avhich they are combined, makes an essential difference in the properties of the compound. It is, however, much less than would be supposed, and even less than the number of possible combinations of simple bodies. Twelve of the simple bodies are oxygen, iodine, chlorine, bromine, fluorine, hydrogen, boron, carbon, phosphorus, sulphur, azote, and selenium ; and forty-one are metals. The five first are called supporters of com- bustion, because they combine with the others, producing a dis- engagement of heat, light, and acidifying principles, and, also, because they are capable of producing acids by a similar combina- tion. The forty-eight others are called simple combustibles, be- cause their union with the supporters of combustion, above men- tioned, is a real combustion. Compound bodies, as has been observed, are not so numerous as might be supposed. They result, 1st. From the combination of koxygen, or one of the other simple supporters of combustion, with one of the simple combustibles; such are the acids. 2nd. From that of a simple body combined, with oxygen, Avith other similar compounds ; such are the salts. 3d. From that of two, CHIMISTRY. 443 three, rarely four simple combustibles, with one another. 4th. From that of oxygen and hydrogen and carbon, forming vegeta] ble matter. 5th. From that of oxygen with hydrogen, carbon and azote, forming animal matter. Combustibles combined with the simple supporters of combustion, are sometimes called burned boelies; from the number of their elements, they are also called binary compounds. When their taste is acid, and they have the property of reddening vegetable blues, they are termed acids. If they are not acid to the taste, and have the property of turning blue what has been reddened by acids, they are distinguished by the termination ide, as oxide, chloride, etc. If only one of the latter class is formed—that is, if the supporter of combustion will unite Avith the combustible in only one proportion, Ave call this compound simply the oxide, chloride, etc. of the combustibles, as oxide of carbon. If they unite in several proportions, we call the first, or that which contains the smallest proportion of oxygen, etc., protoxide, etc,; the second, deutoxide; the third, trioxide. The highest is all called peroxide. So, if only one acid is formed, we designate it by the name of the combustible, with the termi- nation ic. Thus carbon Avith oxygen forms carbonic acid. If several are formed, that which contains the larger proportion of the acidifying principle, is designated by the termination ic, and that Avhich contains less, by the termination ous. Thus sulphur forms sulphuric acid and sulphurous acid. If there are still in- termediate compounds, Ave annex hypo, to designate a lower de- gree of acidity. Thus we should have sulphuric, hyposulphuric; sulphurous, hypo sulphurous. In the acids and oxides, chlorides, etc., the combustible is called the base. When the base is the same, the peroxide, etc. always contains less oxygen, etc., than the loAvest acid. For the names of compounds of two binary burnt bodies, no rules have been adopted to express the union of tAvo oxides, tAvo acids, or an acid with a non-metallic oxide. But those formed of acids and metallic oxides are called salts, and their individual names are formed by changing the termination of the acid, and placing it before the name of the metal; the termi- nation ous is changed into ite, and ic into ate ; sulphurous acid, Avith the oxide of tin, would form sulphite of tin; sulphuric acid and tin, sulphate of tin. If the same acid combines with more than one oxide of the same metal, then we prefix the characteris- 444 MISCELLANEOUS. tic of the oxide to the name of the acid ; thus sulphuric acid, com- bined with the protoxide of iron, forms the protosulphatc ; with the peroxide, the persulphate of iron. Other substances have also the property of uniting Avith acids, neutralizing them, and forming compounds analogous to salts. There are no gene- ral rules for the names of these compounds, but the sub- stances themselves are called salifiable, bases. The rules of no- menclature, in regard to the combination of the combustibles, vary. 1st. If the constituents are metals, they form alloys. 2nd. If the components are solid or liquid, and formed of a metallic and a non-metallic combustible, Ave give to the latter the termination uret; as carbon Avith iron forms carburet of iron. If both are non-metallic, the termination uret may be attached to cither; as, phosphuret of sulphur, or sulphur et of phosphorus. 3d. If the compound is gaseous, Ave name the gas, or one of the gases, if it is composed of two, and join the other component as an adjec- tive, as phosphuretted hydrogen. CHAP. II. ACIDS. Acids : a class of compound bodies, which have the following characteristic properties: ■— The greater part of them have a sour taste,, and most of them are very corrosive. They change the vegetable blues to red, are soluble in water, and have great affinity for the alkaline, earthy, and metallic oxides,' with Avhich they form neutral salts. Some acids have no sour taste, but their affinity for the three classes of bodies above mentioned, is always character- istic. If a few drops of sulphuric acid, nitric acid, or muriatic acid, be added to a solution of blue litmus, it becomes red. The same is the case if they be added to other vegetable colors, as vio- let, etc. Hence these colors are employed as tests of acids; that is, to ascertain Avhen they exist in any substance. We may add the infusion to the fluid in which we are trying to detect an acid, but a more convenient method is, to spread it on paper, and allow it to dry. If a strip of this be put into a fluid in which there is an acid, it instantly becomes red. Some acids appear only in a fluid state—either gaseous, as carbonic acid; or liquid, as sulphu- ric acid: others appear in a solid form, or crystalized, as benzoic acid, boracic acid, etc. All acids are compound bodies, and are sometimes divided into four classes, the three first of which are compounded Avith oxy- gen ; the fourth class consists of those which, at least according to some modern chimists, have no oxygen; e. g., sulphuretted hydrogen. The first class of acids is compounded with oxygen and one other body; the second class comprises the acids com- pounded of carbon, hydrogen, and oxygen; the third class con- sists of those acids which contain nitrogen, in addition to the three substances above mentioned. The ancient chimists were acquaint- ed Avith but few of the acids now known; they divided them, ac- 446 MISCELLANEOUS. cording to the kingdoms of nature, into mineral, vegetable, and animal acids. This division, hoAvever, cannot be retained, as there are some acids Avhich appear in all the kingdoms; e. g., phospho- ric acid. If the same radical be compounded Avith different pro- portions of the acidifying principle, forming different acids, the most poAverful acid receives a name from the radical, terminating in ic; the Aveaker, a name formed in the same manner, in ous: e. g., sulphurous and sulphunc acid, nitrous andnitnc acid; and, where there are intermediate compounds, the term hypo is occa- sionally added to the compound next above it in point of acidity: thus, hyposv\oYmxic acid, signifies an intermediate acid between sulphurous and sulphuric acids; /«/j»ophosphorous acid, an acid containing less oxygen than the phosphorous acid. ALKALIES. Alkali : in chimistry, from the Arabian kali, the name of a plant from the ashes of Avhich one species of alkali can be ex- tracted. The substances that are met Avith under the denomina- tion of alkaline, are possessed of certain peculiar properties; they are mainly characterized, hoAvever, by a poAver of combining with acids, in such a manner as to impair the activity of the latter; so that alkalies, as chimical agents, are distinguished by properties the reverse of acids; and alkalies are, therefore, generally consid- ered as antagonist substances. Besides the power of neutralizing acids, and thereby forming certain saline substances, the alkalies are further distinguished by the following properties: 1st, they have an acrid taste and corro- sive poAver when applied to some substances, thus proving caustic to the skin and tongue; 2d, they change vegetable blue to green, and red to purple, and yelloAV to a reddish-brown; 3d, they are almost indefinitely soluble in water—that is, they combine with it in every proportion; 4th, they unite with oils and fats, and form by this union the well known compound called soap. There is another class of substances which have a strong analo- gy to alkalies, especially in the particular of opposition to acids; namely, the earths. Some of these, indeed, have been classed by Fourcroy among the alkalies; but they have been kept separate ALBUMEN. 447 by others, on the ground that the analogy between them is far from amounting to an identity of properties. The true alkalies have been arranged, by a modern chimist, into three classes: 1st, those which consist of a metallic basis, combined with oxygen— these are three in number; potash, soda, and lithia: 2d, those Avhich contain no oxygen; namely, ammonia: 3d, those contain- ing oxygen, hydrogen, and carbon; in this class are placed aco- nita, atropia, brucia, cicuta, datura, delphia, hyosciama, morphia, and strychnia. It is supposed that the vegetable alkalies may be found to be as numerous as the vegetable acids. The original dis- tribution of alkaline substances was into volatile and fixed, the volatile alkali being known under the name of ammonia; while, of the two fixed kinds, one Avas called potash, or vegetable, be- cause procured from the ashes of vegetables generally; the other, soda, or mineral, on account of its having been principally ob- tained from the incineration of marine plants. ALBUMEN. Albumen, in physiology, exists nearly pure in the white of eggs. As thus procured, it is a glareous fluid, Avith very little taste. When kept for some time exposed to air, it purifies, but, when spread in thin layers and dried, it does not undergo any changes. When heated to about 165° Fahr., it coagulates, and its properties are entirely changed. It is soluble in cold Avater, and is separated, in its coagulated state, by hot water, if the quan- tity of fluid be not great; but, if the water be about ten times as much in amount as the albumen, there is no coagulation. Hence we cannot dissolve it in warm water, for when put into it, it is in- stantly coagulated. It is also coagulated by acid. It exists in different parts of animals, as cartilages, bones, horns, hoofs, flesh, the membranous parts, and, in considerable quantity, in blood, from Avhich it is usually procured, Avhen required in the arts. From the property which it possesses, of being coagulated by heat, it is employed for clarifying fluids, as in the refining of sugar, and many other processes. When required in a large quantity, bullock's blood is used. When this, or the white of eggs, is put into a warm fluid, its albumen is coagulated, and en- 448 MISCELLANEOUS. tangles the impurities, and, as the scum rises, it is removed. Al- bumen acts in the same way, also, in clarifying spirituous fluids. When, for instance, the Avhite of an egg is added to Avine, or to any cordial, the alcohol coagulates it, and the coagulum entangles the impurities, and carries them to the bottom. Both gelatin and albumen exist in flesh, and, as the former is soluble in Avarm Avater, hence the difference in the nutritious quality of butcher's meat, according to the mode of cooking it; Avhen, for instance, meat is boiled, the greater part of the gelatin is extracted, and retained by the soup; Avhen, on the contrary, it is roasted, the gelatinous matter is not removed; so that, roasted meat contains both gelatin and albumen, and should, therefore, be more nutritious than the other. By the analysis of Gay Sussac and Thenard, 100 parts of albumen are formed of 52.883 carbon, 23.872 oxygen, 7.540 hy- drogen, 15.705 nitrogen. The negative pole of a voltaic pile in high activity, coagulates albumen. Orfila has found the Avhite of eggs to be the best antidote to the poisonous effects of corrosive sublimate on the human stomach. BENZOIN. Benzoin is a solid, fragile, Aregetable substance, of a reddish broAvn color. In commerce, tAvo varieties are distinguished, viz., the common and the amygdaloidal, the latter containing Avhitish tears, of an almond shape, diffused through its substance. It is imported from Samatra, Siam, and Java, and is found, also, in South America. Benzoin is obtained from the tree called styrax benzoin, and perhaps from some others. On making incisions into the bark, it Aoavs out in the form of a balsamic juice, having a pungent .taste, and an agreeable odor. The pure balsam con- sists of tAvo principal substances, viz., a resin, and a peculiar acid termed benzoic, Avhich is procured from the mass, by sublimation. It is soluble in Avater. This acid is found, also, as a constituent principle in storx, and the balsams of Tolu and Peru. It exists in the urine of coavs, camels, and even of young children. It is sometimes found in a crystaline form on the pods of the vanilla. Benzion is not soluble in Avater, but is readily dissolved in alcohol, by the aid of a gentle heat. The tincture thus made is used in CAUSTIC POTASSA.--CAUSTUS. 449 pharmacy. A small quantity of this tincture, dropped into Avater, forms a Avhite, milky fluid, Avhich, is used in France as a cosmetic, under the name of lait virginal. The gum is a principal ingredi- ent of the common court plaster. The acid, as Avell as the gum, is employed in medicine; they are stimulating, and act more par- ticularly upon the pulmonary system; whence they are used in asthma, and chronic catarrh. CAUSTIC POTASSA. Caustic potassa : impure hydrate of protoxide of potassium ; caustic kali Avith lime; common caustic. This is seen in flat, ir- regular, brittle pieces, or in round sticks, like the nitrate of silver; of a grayish Avhite, sometimes reddish ; of a savor extremely caustic, and a slight odor sui generis. This substance is extreme- ly caustic; it decomposes quickly the parts Avith Avhich it is put in contact, and leaves on the skin a soft, grayish eschar, Avhich comes off slowly. Taken internally, it acts in the same way as all corrosive poisons ; it has, nevertheless, been administered, in very dilute solutions, as an antacid, diuretic, and lithontriptic. It has succeeded in the gravel, in nephritic colics, and other af- fections, proceeding from superabundance of uric acid. It has been recommended, likeAvise, in the treatment of scrofula, and in some diseases of the skin, such as leprosy, etc. This solution, even Avhen very diluted, soon irritates the stomach, and brings on anoreaxia, which prevents it from being used for any length of time. CAUSTUS. The name of caustic is given to substances, Avhich, by their chimical action disorganize the parts of the body with Avhich they are put in contact. They are called, likewise, potential cauteries, to distinguish them from the fire called actual cautery. Caustics, in general, act by decomposing chimically the tissues to which they are applied, by depriving them pf life, and produc- ing a real local and circumscribed gangrene, called eschar, or 57 450 MISCELLANEOUS. slough. Those, the action of Avhich is poAverful, for instance, caustic potassa, concentrated sulphuric acid, etc., produce these phenomena Avith such rapidity, that inflammation takes place on- ly after the formation of the eschar; Avhilst, on the contrary, in- flammation is the immediate consequence of the less energetic caustics. In both cases, suppuration occurs sooner or later, and separates the disorganized from the surrounding parts. Almost all the substances used as caustics have only a local action ; some, hoAvever, are capable of being absorbed, and of exercising a dele- terious action on the economy in general; arsenical preparations are an instance of it. The employment of caustics is noAV confined to a small num- ber of cases. The actual cautery, and the knife, are, in general, preferred to them. They are used, principally, in order to estab- lish issues, particularly in cases in Avhich it is necessary to pro- duce a poAverful derivation ; to stop the progress of certain gan- grenous affections, such as anthrax ; to open certain indolent ab- scesses ; to change the mode of vitality of the skin, in some can- cerous or heapetic ulcers ; to destroy the excrescences of wounds or proud flesh ; and, finally, to prevent the absorption of the virus, deposited at the surface of poisoned Avounds. ESSENTIAL OILS. This name is applied to those volatile fluids usually obtained from aromatic plants, by subjecting them to distillation with water. The oil is volatilized with the aqueous vapor, and is easily con- densed ; a small portion of it is retained in solution by the water; but the greater part separates, and is obtained pure from the diffe- rence in their specific gravity. In some instances, as, for example, in the rind of the orange and lemon, the oil exists in distinct ve- sicles, and may be obtained by expression. The principal volatile or essential oils are those of turpentine, anniseed, nutmeg, lavender, cloves, caraway, peppermint, sassa- fras, camomile, and citron. The taste of these oils is acrid and burning, and their odor very pungent, generally resembling the taste and smell of the vegetables affording them. They are gene- rally fluid, and remain so even at a low temperature ; but some DECOMPOSITION, CHIMICAL. 451 congeal at a very moderate degree of cold, and others are naturally concrete. They are extremely volatile, and boil at a temperature considerably above that of boiling water: thus oil of turpentine boils at 315°. They are very soluble in strong alcohol: but, on adding water largely, are precipitated; they are soluble in ether, in like manner, but do not form soaps with the alkalies, by which they are distinguished from the fixed oils. They are readily in- flamed by strong nitric acid, especially with the precaution of ad- ding a little sulphuric acid to render the former more concentrated. Exposed to the action of the air, they undergo an alteration in consequence of the absorption of oxygen, become thickened, and gradually change into a solid matter resembling the true resins. When digested with sulphur, they unite with it, forming what have been called balsams of sulphur. One of the most useful and abundant of the essential oils is that of turpentine, commonly called spirit of turpentine. It is obtain- ed by distilling turpentine and Avater, in due proportions, from a copper alembic. It is perfectly limpid and colorles, has a strong smell, a bitterish taste, boils at 316°, and is extremely inflam- mable. It is the solvent employed in making a variety of var- nishes ; but, for purposes of nicety, it requires to be rectified by a second distillation. In general, the volatile oils are used in the practice of medicine, or as perfumes. Those applied to the latter use, as the essence of rose, of jasmine, violet, etc., are possessed of a more feeble odor, and, being obtained from the fhnvers of their respective plants, re- quire much care in their preparation. This is done by spreading upon white wool, impregnated with olive oil, the petals of the flowers, and leaving them for some time, covered over Avith a Avoollen cloth, upon Avhich flowers are also scattered ; the flowers are renewed from time to time, until the olive oil employed ap- pears to be saturated Avith the oil of the flowers, when this last is separated by digesting the wool in alcohol. DECOMPOSITION, CHIMICAL. Decomposition, Chimical, is the resolution of a compound sub- stance into its constituent parts, which are exhibited either sepa- 452 MISCELLANEOUS. rate, or in some new combination. The compounds Avhich arc spontaneously formed by organic bodies, both vegetable and ani- mal, are of a different nature from those Avhich exist in unorganiz- ed matter. They are the peculiar results of vital process, and neither their structure nor composition can be imitated by art. During life, the elements of organic bodies are held together by vital affinities, under the influence of Avhich they Avere originally combined. But no sooner does life cease, than these elements be- come subject to the laAvs of inert matter. The original affinities, Avhich had been modified or suspended during life, are brought into operation ; the elementary atoms react upon each other, new combinations are formed, and the organized structure passes, soon- er or later, into decay. The rapidity with Avhich decomposition takes place in organic' bodies depends upon the nature of the particular substances, and upon the circumstances under Avhich it is placed. Temperature, moisture, and the presence of decomposing agents, greatly affect both the period and extent of this process. CHAP. III. ORIGIN AND REGULATION OF ANIMAL HEAT. The true sources of animal heat are still imperfectly known. Its regular production, hoAvever, is an essential condition of life. If the human body did not possess within itself the power of ge- nerating heat, so as to maintain nearly an equality of temperature in all climates, it could not long exist. In winter, and especially in the northern regions, the blood would speedily be converted into a solid mass, and life be extinguished, if no provision existed, for replacing the caloric withdrawn from the system by the sur- rounding cold. In most parts of the globe, the heat of the atmos- phere is, even in summer, inferior to that of the human body, and consequently a loss of caloric is always going on, which must be made up in some way, otherAvise disease and death would speedi- ly ensue. In cholera, a very remarkable diminution of heat oc- curs, and a return of the natural temperature is an indispensable step towards recovery. The relation between the productien of animal heat, and tha condition of the respiratory functions, is the most direct and re- markable. In general, other conditions being alike, heat is gene- rated more or less freely, in proportion to the size and vigor of the lungs ; and when these are impaired, the production of heat is diminished. Hence many persons, with imperfectly developed lungs, and a predisposition to consumption, complain habitually of coldness of the surface and feet; and many who were previ- ously in good health, became more and more sensible to cold, in proportion as the approach of disease weakened the functions of the lungs. I have noticed this increased sensibility to cold, as precursor of chronic pulmonary disease, both in myself and others, 454 MISCELLANEOUS. before any other very ostensible symptom had appeared, and think I have seen its further progress arrested by the timely use of proper means, Avhere much greater difficulty Avould have been ex- perienced had the warning not been attended to. The generation of heat in the living system being so immedi- ately connected Avith the lungs, Ave find the temperature highest in those animals avIio possess them in the greatest perfection, viz. birds. In many species, the internal heat exceeds that of man by tAventy or thirty degrees ; Avhile that of man exceeds, to as great an extent, the heat of such of the inferior animals as are re- remarkable for imperfect organs of respiration. The next condition affecting the production of animal heat, is the co-operation of the nervous system. If the mind be depressed by grief, tormented by anxiety, or absorbed in sedentary medita- tion, all the bodily functions become weakened, the circulation languishes, the breathing becomes slow and scarcely perceptible, digestion is ill-performed, and coldness of the extremities ensues. If, on the other hand, the mind and nervous system be stimulated by cheerful exertion and agreeable emotion, a pleasant glow per- vades the frame, and external cold is much more easily resisted. The quantity and quality of the food, and the state of the di- gestive functions, are also important conditions. This will be readily assented to, Avhen the reader considers that a due supply of well-formed chyle is required to restore the nourishing proper- ties of the blood, and that if, in consequence either of insufficient food or weak digestion, this be rendered impossible, all the animal functions, and, among others, the production of heat, are necessa- rily impaired. This is the reason why coldness of the feet, and chilliness of the surface are so generally complained of in indiges- tion and bilious complaints. Every body knows that exercise favors, and indolence obstructs the development of animal heat. Exercise produces its effect by the general stimulus which it gives directly to the respiratory and circulating systems, and indirectly to the nervous and digestive functions. In attempting, therefore, to increase the power of resistence to cold in the human body, we ought to take into account all the conditions which favor the generation of heat. Observation proves that the degree of cold required to overcome the internal genera- ANIMAL HEAT. 455 ting power, and to extinguish life, varies in the same individual at different times; and, therefore, our protecting measures ought also to be varied according to the state of the constitution, the vigor of the respiratory and digestive functions, the kind of food, and the amount of exercise. When food is inadequate, and the mind de- pressed, the system resists the impression of cold with great diffi- culty ; and even in Scotland, where the temperature is rarely very low, scarcely a winter passes without several instances of death occurring from exposure in ill-fed and ill-clothed individuals, even when the thermometor is above the freezing point. This happens usually, Avhen the Avind aids the rapid abstraction of heat. Well- fed and well-clothed guards of coaches, on the other hand, are re- markable examples of the poAver of Avithstanding low temperatures in very exposed situations, Avhere the animal functions are in a state of vigor. The recent Arctic expeditions under Parry and Franklin, afforded similar instances. If the use of suitable cloth- ing is found insufficient to keep the body warm, we may infer with certainty, although no other sign of bad health has appeared, that some internal cause exists, affecting and imparing one or the other of the sources of animal heat already mentioned, and that till the special cause be discovered and removed, the evil itself will continue undiminished. In Avinter, young people often suffer from being daily confined, for many hours in succession, without exercise, in rooms insuffi- ciently heated. This is a constant subject of complaint in large academies and boarding-schools, Avhere economy in fuel is carried to its utmost limits. Nothing tends more than this to lower the general standard of health, and prepare the individual for the fu- ture inroads of insidious disease. In scrofulous children, espe- cially, in whom the evolution of heat is rarely energetic, the evil is one of great magnitude; for the chilblains, colds, and head- aches, more immediately complained of, are often its least import- ant consequences. It is far from my wish to recommend that the young of either sex should be brought up in the relaxing atmo- sphere of over-heated rooms. On the contrary, comfortable warmth ought, in every instance, to be drawn chiefly from its le- gitimate sources—free respiration in a pure air, abundant out-door exercise, vigorous digestion, and an actively employed mind. If these conditions be observed, little fire will be required, to supply 456 MISCELLANEOUS. warmth to the young. But if, as often happens, these be neglect- ed, and the generation of animal heat be thereby reduced too Ioav, Ave must either allow the mischief to go on increasing, or afford an adequate Avarmth from Avithout. It is in vain to think of rendering young creatures hardy, by subjecting them to the continued influ- ence of a depressing temperature. A few may escape, but the majority will certainly suffer. DR. ARNOTT'S HYDROSTATIC BED FOR INVALIDS. In many diseases Avhich afflict humanity, more than half of the suffering and danger is not really a part of the disease, but the ef- fect or consequence of the confinement to which the patient is sub- jected. Thus, a fracture of the bone of the arm is as serious a local injury, as a fracture of one of the bones of the leg; but the former leaves the patient free to go about and amuse himself, or attend to business as he Avills, and to eat and drink as usual'—in fact, hardly renders him an invalid; while the latter imprisons the patient closely upon his bed, and brings upon him, first, the irk- someness of the unvaried position, and then the pains of the une- qual pressure borne by the parts on Avhich the body rests. These, in many cases of confinement, disturb the sleep and the appetite, and excite fever, or such constitutional irritation, as much to re- tard the cure of the original disease, and not unfrequently to pro- duce new and more serious disease. That complete inaction should prove hurtful to the animal system, may by all be at once conceived; the operation of the continued local pressures Avill be understood from the following statements. The health and even life of every part of the animal body depends on the sufficient circulation through it of fresh blood driven in by the force of the heart. Now, when a man is sitting or lying, the parts of the flesh compressed by the Aveight of the body do not receive the blood so readily as at other times ; and if, from any cause, the action of his heart becomes weak, the inter- HYDROSTATIC BED. 457 ruption will both follow more quickly and become more complete. A peculiar uneasiness soon arises where the circulation is thus ob- structed, impelling the person to change of position; and a heal- thy person changes as regularly, and with as little reflection, as he winks to wipe and moisten his eye-balls. A person weakened by disease, hoAvever, Avhile he generally feels the uneasiness soon- er, as explained above, and, therefore, becomes Avhat is called rest- less, makes the changes Avith much fatigue: and, should the sen- sations, after a time, become indistinct, as in the delirium of fever, in palsy, etc., or should the patient have become too weak to obey the sensation, the compressed parts are kept so long without their natural supply of blood that they lose their vitality, and become what are called sloughs or mortified parts. These have, after- wards, to be thrown off, if the patient survive, by the process of ulceration, and they leave deep holes, requiring to be filled up by neAv flesh, during a tedious convalescence. Many a fever, after a favorable crisis, has terminated fatally from this occurrence of sloughing on the back or sacrum; and the same termination is common in lingering consumptions, palsies, spine diseases, etc., and generally in diseases which confine the patients long to bed. It was to mitigate all, and entirely to prevent some, of the evils attendant on the necessity of remaining in a reclining posture, that the hydrostatic bed was contrived. It was first used under the fol- loAving circumstances: A lady, after her confinement, which occurred prematurely, and Avhen her child had been for some time dead, passed through a combination and succession of low fever, jaundice, and phlegmasia dolens of one leg. In her state of extreme depression of strength and of sensibility, she rested too long in one posture, and the parts of the body on which she had rested all suffered; a slough formed on the sacrum, another on the heel: and, in the left hip, on Avhich she had lain much, inflammation began, which terminated in ab- scess. These evils occurred while she was using preparations of bark, and other means, to invigorate the circulation, and while her ease and comfort were Avatched over by the affectionate assiduity of her mother, with numerous attendants. After the occurrence, she was placed upon the bed contrived for invalids by Mr. Earle, fur- nished for this case with pillows of down, and of air of various sizes, and, out of its mattress, portions were cut opposite to the slough- 58 45S MISCELLANEOUS. ing parts; and Mr. Earle himself soon afforded his valuable aid. Such, hoAvever, Avas the reduction of the poAvers of life, that, in spite of all endeavors, the mischief advanced, and, about a Aveek later, during one night, the chief slough on the back Avas much en- larged, another had formed near it, and a new abscess Avas produ- ced in the right hip. An air-pillow had pressed Avhere the sloughs appeared. The patient Avas, at that time, so weak that she gene- rally fainted Avhen her Avounds Avere dressed; she Avas passing days and nights of uninterrupted suffering, and, as all knoAvn means seemed inefficient to relieve her, her life Avas in imminent danger. Under these circumstances, the idea of the hydrostatic bed oc- curred to me. Even the pressure of an air-pilloAv had killed her flesh; and it Avas evident that persons in such a condition could not be saved un- less they could be supported Avithout sensible inequality of pres- sure. I then reflected that the support of water to a floating body is so uniformly diffused that every thousandth of an inch of the in- ferior surface has, as it Avere, its oavu accurate liquid pillar, and no one part bears the load of its neighbor; that a person resting in a bath is nearly thus supported; that this patient might be laid upon the surface of a bath over Avhich a large sheet of the Avater- proof India rubber cloth Avas previously throAvn, she being render- ed sufficiently buoyant by a soft mattress placed beneath her ; thus would she repose on tho face of the Avater like a sAvan on its plu- mage, Avithout sensible pressure any Avhere, and almost as if the Aveight of her body were annihilated. The pressure of the atmo- sphere on our bodies is of fifteen pcur.ds per square inch of its surface : but, because uniformly diffused, is not felt. The pres- sure of a Avater bath, of depth to cover the body, is less than half a pound per inch, and is similarly unperceived. A lied, such as then planned, Avar, immediately made. A trough of convenient length and breadth, and about a foot deep, Avas lined Avith metal to make it Avater-tight; it Avas about half filled Avith Avater, and over it Avas thrown a sheet of the India rubber cloth as lar^c as would be a complete lining to it empty. Of this sheet, the edges, touched Avith varnish to prevent the water from creeping round by capillary attraction, Avere afterAvards secured in a Avater-tight man- ner all round the upper border or top of the trough, shutting in the HYDROSTATIC BED. 459 water as closely as if it had been in bottles, the only entrance left being through an opening at one corner, Avhich could be perfectly closed. Upon this expanded dry sheet, a suitable mattress Avas laid, and constituted a bed ready to receive its pilloAV and bed clothes, and not distinguishable from a common bed but by its most surpassing softness or yielding. The bed was carried to the pa- tient's house, and she Avas laid upon it; she Avas instantly relieved in a remarkable degree, SAveet sleep came to her, she awoke re- freshed, she passed the next night much better than usual, and, on the folloAving day, Mr. Earle found that all the sores had assumed a healthy appearance ; the healing from that time Avent on rapidly, and no neAv sloughs were formed. When the patient Avas first laid upon the bed, her mother asked her Avhere the down pilloAvs, Avhich she before had used, were to be placed; to Avhich she an- SAvered, that she knew not, for that she had no pain left to direct; in fact, she needed them no more. It may be here recalled to mind, that the human body is nearly of the specific gravity of Avater, or of the weight of its bulk of Avater, and, therefore, as is knoAvn to swimmers, is just suspended or upheld in water Avithout exertion, when the SAvimmer rests tranquilly on his back Avith his face upwards. He then displaces Avater equal to his OAvn body in Aveight as Avell as in bulk, and is supported as the displaced Avater Avould have been. If his body be tAvo and a half cubical feet in bulk, (a common size.) he v/ill just displace two and a half cubic feet of Avater, equal in Aveight to his body. If, however, instead of displacing the water with his mere body, he chooses to have something around or under him Avhich is bulky Avith little Aveight, as the mattress of the bed above described, Avhen his Aveight has forced tAvo cubical feet under the level of the water around, he will float four-fifths of his body above the level, and will sink much less into his floating mattress, than a person sinks in an ordinary feather bed. It thus appears that, by choosing the thickness of the mattress, and if unusual positions are required, by having different thickness in different parts, or by placing a bulk of folded blanket, or of pilloAV, over or under the mattress, in certain situations, any desirable position of the body may be easily obtained. This bed is a warm bed, OAving to the Avater being nearly an absolute non-conducter of the heat from above doAViiAvards, and 460 MISCELLANEOUS OAving to its alloAving no passage of cold air from beloAV. From this last fact, hoAvever, less of the perspiration, Avhether sensible or insensible, will be carried off by the air, than in a common bed ; and unless the patient can leave the bed daily, to let it be aired, it is necessary to lay an oiled silk, or other water-proof cloth, over the mattress, to prevent the perspiration from descending, to be condensed on the cloth below; or to place a blanket below, to be changed occasionally; or, finally, to lay under the mattress a layer of Cork, cut into small pieces, so connected as to leave air passages betAveen, for any desirable degree of ventilation. This bed is in itself as dry as any bed can be; for the India rubber cloth, (of Avhich bottles can be made,) is quite impermeable to Avater, and the maker is noAV preparing cloth expressly for this purpose. Sir Humphrey Davy recommended that his safety lamp should be double; some persons may prefer a double sheet, to avoid the possibility of accident. Unlike any other bed that ever was contrived, it allows the pa- tient, Avhen capable of only feeble efforts, to change his position, almost like a person swimming, and so to take a degree of exer- cise, affording the kind of relief Avhich, in constrained positions, is obtained by occasional stretching, or which an invalid seeks by driving out in a soft springed carriage. It exceedingly facilitates turning for the purpose of dressing wounds; for, by raising one side of the mattress, or depressing the other, or merely by the pa- tient's extending a limb to one side, he is gently rolled over, near- ly as if he were simply suspended in water; and it is possible even to dress Avounds, apply poultices, or place vessels under any part of the body, without moving the body at all, for there are some inches of yielding water under the body, and the elastic mattress may, at any part, be pushed down, leaving vacant space there, without the support being lessened for the other parts. Then, Avith all the advantages which other invalid beds possess, and Avith those Avhich are entirely its own, it may be made so cheaply, that even in hospitals, Avhere economy most prevails, it may at once be adopted for many of the bed-ridden. The author has noAV seen enough of the effects of this bed, to make him feel it a duty at once to publish a notice of it. With it, evidently, the fatal termination called sloughing, now so com- mon, of fevers and other diseases, need never occur again. And HUNGER. 461 not only will it prevent that termination, but, by alleviating the distress through the earlier stages, it may prevent many cases from ever reaching the degree of danger. Then it is peculiarly appli- cable to cases of fractured bones, and other surgical injuries; to palsies, disease of the hip-joint and spine, and universally Avhere persons are obliged to pass much time in bed. And in all cases of curvature of the spine, either actually existing or threatened, it affords a means of laying the patient in any desired position, and with any degree of pressure incessantly urging any part of the spine back to its place. If used without the mattress, it becomes a warm or a cold bath, not allowing the body, however, to be touched by the water; and in India it might be made a cool bed for persons sick or sound, during the heats which there prevent sleep, and endanger health. There are numerous other profes- sional adaptations and modifications of it, which readily occur to practitioners sufficiently versed in the department of natural philo- sophy (hydrostatics) to which it belongs. Before reflection, a person might suppose a resemblance between it and an air-bed or pillow, calling this a water bed or pillow; but the principles of the two are perfectly distinct or opposite. An air pillow supports by the tension of the surface, Avhich encloses the air, and is there- fore like a hammock, or the tight sacking under the straw mat- tress of a common bed, and really is a hard pillow; but, in the hydrostatic bed, there is no tense surface or web at all: the patient is floating upon the water, on which a loose sheet is lying, merely to keep the mattress dry, and every point of the body is supported by the Avater immediately beneath it. To recall the difference here described, and which is of great importance, the bed is better described by the appellation of hydrostatic bed than of water bed. HUNGER; The feeling of a want of food. When the stomach has digested and disposed of the food and drink which it contained, its peculiar nervous power is destroyed, and some time is necessary before it collects it again. This time is shorter, in proportion as the indi- vidual is healthy, young, strong and active. As soon as this ner- vous poAver is restored, the activity of the organ is again awaken- 462 MISCELLANEOUS. ed, and produces a longing to eat, Avhich Ave call, in its first de- gree, appetite. If this is not gratified, it gains strength, and be- comes hunger. Appetite is not a disagreeable feeling, but hunger is an ever-in- creasing pain, on account of the ever-increasing scnsibliity of tbe nerves of the stomach. To some men, Avhose stomachs are mor- bidly sensitive, the first desire for food is unpleasant; and if this desire is not immediately gratified, they are seized with griping pains in the parts about the stomach, Avhich, if not appeased, are folloAved by sudden Aveakness, and even fainting. If hunger be not satisfied, a dreadful state of the body ensues, aud finally death. After long-continued hunger, the blood becomes Aveak, acrid and thin, on account of the want of materials to compensate for the nutritious matter expended in the support of the body; hence the Avhole body becomes lean and Aveak; bloody fluxes take place from all parts, as Avell as violent irritation of the nervous system, caused by the excessive sensibility of the nerves of the stomach, which, at length, extends to the Avhole region of the abdomen ; is carried to a still greater height, and produces pain over the Avhole body; sleeplessness; convulsion; raving madness; until, at length, death puts an end to the scene. There is a mode of curing diseases by the greatest possible ab- stinence from food ; so much only being alloAved, as is requisite to keep the patient alive. The food is diminished by degrees; and, in the period of convalescence, is increased in the same Avay, Avith much precaution, as many patients, unable to resist their appetite, have ^died in consequence of a slight indulgence. This mode of cure has been found of great use in the cases of deep- rooted complaints, which baffled the powers of medicine. It is applied particularly in connection Avith frequent unctions of mer- cury ; in obstinate cases of syphilis, Avhen even the bones have become affected; and the bases in which this severe remedy has produced brilliant .successes, are numerous. It is considered, in Germany, as indispensable to the cure of inveterate syphilis. The patient is kept in a avell-closed room, receiving only a little bread and Avater, and soon loses his appetite, owing to his debilitated state, produced by the mercurial unctions. His bed-linen is never changed, nor the room aired; indeed, a very trifling draught of ALIMENT. 463 air has proved fatal. The salivation is very great, and it is sur- prising that man can live at all in such a state as these patients are often in. The cure generally requires about three weeks. ALIMENT. Aliment : a term which includes every thing serving as nutri- ment for organized beings. In animals and vegetables, we can observe the phenomena of decomposition and reproduction, and analyze the substances that administered to their groAvth. Gene- rally, hoAvever, the word aliment is used for whatever serves as nutriment to animal life. It is, in this respect, a subject of great interest to the zoologist. In the present article, Ave shall confine ourselves to the aliment of mankind. Man, it is Avell knoAvn, derives nourishment both from animal and vegetable substances. He eats fruits, both ripe and unripe; roots, leaves, floAvers, even the pith and the bark of different plants, many different parts of animals, and the Avhole of some. Cli- mate, custom, religion, the different degrees of Avant and of civil- ization, give rise to an innumerable diversity in food and drink, from the repast of the cannibal of NeAv-Zealand, to that of a Pa- risian epicure; from the diet of the carnivorous native of the North, to that of the Brahmin, whose appetite is satisfied Avith vegetables; from the oak-bark bread of the Norwegian peasant, to the luxuriantly served table of a Hungarian magnate at Vienna. Some nations abhor Avhat others relish, and great Avant often ren- ders acceptable Avhat, under other circumstances, Avould have ex- cited the greatest disgust. The flesh of dogs is commonly eaten in China, and in Africa that of snakes, particularly of the rattle- snake aud boa constrictor. Locusts are eaten both in Asia and Africa, and the Negroes on the coast of Guinea relish lizards, mice, rats, snakes, caterpillars, and other reptiles and Avorms. The Otomacs, a tribe of American Indians, are said by Humboldt to collect a kind of clay, to be eaten in the rainy season. It is an interesting subject, as yet by no means sufficiently in- vestigated, hoAV far the different aliment of various countries is connected Avith the climate, etc., and Avhat influence it exerts on the different races, as Avell as the consequence of introducing new 464 MISCELLANEOUS. species of aliments. Some excellent remarks on the national dish- es of different nations, Avere published by Baron Rumor, a Ger- man, in 1822, in a Avork Avhich he called Kochkunst. All kinds of aliment must contain nutritious substance, Avhich, being extracted by the act of digestion, enters the blood, and ef- fects, by assimilation, the repair of the body. Alimentary matter, therefore, must be similar to animal substance, or transmutable into such. In this respect, alimentary substances differ from medicines, because the latter retain their peculiar qualities in spite of the or- gans of digestion, and Avill not assimilate Avith the animal sub- stance, but act as foreign substances, serving to excite the activity of particular organs or systems of the body. All alimentary sub- stances must, therefore, be composed, in a greater or less degree, of soluble parts, Avliich easily lose their peculiar qualities in the process of digestion, and correspond to the elements of the body. These substances, in their simple state, are mucilage, gelatin, glu- ten, albumen, farina, fibrin, and saccharine matter. Of these, vegetables contain chiefly mucilage, saccharine matter, and farina; Avhich latter substance, particularly in connection Avith the vegeta- ble gluten—by Avhich both become apt for fermentation, and thus for dissolution and digestion—is the basis of very nutritious food. The nutritive part of fruits consists of their saccharine matter and a little mucilage. In animal food, gelatin is particularly abundant. The nutritiousness of the different species of food and drink de- pends, therefore, upon the proportion Avhich they contain of those substances, and the mode in Avhich they are connected, favoring or opposing their dissolution. Organs of digestion in a healthy state dissolve alimentary substances more easily, and take up the nutri- tious portions more abundantly, than those of which the strength has been impaired so that they cannot resist the tendency of each substance to its peculiar chimical decomposition. The Avholesome or unAvholesome character of any aliment depends, therefore, in a great measure, on the state of the digestive organs, in any given case. Sometimes a particular kind of food is called wholesome, because it produces a beneficial effect, of a particular character, on the system of an individual. In this case, hoAvever, it is to be considered as a medicine, and can be called Avholesome only for those whose systems are in the same condition. Very often a sim- ple aliment is made indigestible by artificial cookery. Aliments ALIMENT. 465 abounding in fat are unwholesome, because fat resists the operation of the gastric juice. The addition of too much spice makes many an innocent aliment injurious, because spices resist the action of the digestive organs, and produce an irritation of particular parts of the system. They are introduced as artificial stimulants of ap- petite. In any given case, the digestive power of the individual is to be considered, in order to determine whether a particular ali- ment is wholesome or not. In general, therefore, we can only call that aliment healthy, which is easily soluble, and is suited to the digestive powers of the individual; and, in order to render the aliment perfect, the nutritious parts must be mixed up with a cer- tain quantity of innocent substance affording no nourishment, to fill the stomach; because there is no doubt that many people injure their health by taking too much nutritious food. In this case, the nutritious parts Avhich cannot be dissolved, act precisely like food which is in itself indigestible. In Prussia and Austria, where, as under many other despotic governments, the medical police is very good, the public officers pay much attention to aliment, and are careful that provisions exposed to sale be of a good quality, and particularly that no decayed or adulterated articles be sold to the poor. Such regulations exist, to a certain extent, in England, France, the United States, and, in fact, in every civilized country. The kind of aliment used influences the health, and even the character of man. He is fitted to derive nourishment both from animal and vegetable life, but can live exclusively on either. Ex- perience proves that animal food most readily augments the solid parts of the blood, the fibrin, and, therefore, the strength of the muscular system, but disposes the body, at the same time, to in- flammatory, putrid, and scorbutic disease, and the character to vio- lence and coarseness. On the contrary, vegetable food renders the blood lighter and more liquid, but forms weak fibers, disposes the system to the diseases which spring from feebleness, and tends to produce a gentle character. Something of the same difference of moral effect results from the use of strong or light wines. But the reader must not infer that meat is indispensable for the support of the bodily strength. The peasants of some parts of Switzer- land, who hardly ever taste any thing but bread, cheese, and but- ter, are vigorous people. The nations of the North incline, gene- rally, more to animal diet; those of the South, and the Orientals, 59 466 MISCELLANEOUS. more to vegetable. These latter are generally more simple in their diet than the former, Avhere their taste has not been corrupted by luxurious indulgence. Some tribes in the East, and the caste of Brahmins in India, live entirely on vegetable food. The inhabit- ants of the most northern regions live almost entirely upon animal food, scarcely ever partaking of any vegetable substance, at least during the greater part of the year. Some nations feed chiefly on terrestrial animals, others on aquatic ones. DIET. The dietetic part of medicine is an important branch, and seems to require a much greater share of attention than it commonly meets with. A great variety of diseases might be removed by the observance of a proper diet and regimen, without the assistance of medicine, were it not for the impatience of the sufferers. It may, however, on all occasions, come in as a proper assistant to the cure. That food is, in general, thought the best and most con- ducive to long life, which is most simple, pure, and free from ir- ritating qualities, and is capable of being most easily converted into the substance of the body, after it has been duly prepared by the art of cookery; but the nature, composition, virtues and uses of particular aliments can never be learned to satisfaction, without the assistance of practical chimistry. Diet drink, an alterative decoction, employed daily in consi- derable quantities, at least from a pint to a quart. The decoction of sarsaparilla and mezereon, the Lisbon diet-drink, is the most common and most useful. DIGESTION. Digestion is that process in the animal body, by which the ali- ments are dissolved, and the nutritive parts separated from those Avhich cannot afford nourishment to the body. The organs effec- ting this process are divided into the digestive organs, properly so called, and the auxiliary organs. The former are composed of the division of the intestinal canal, which includes the stomach, DIGESTION. 467 the great and small intestines, etc. To the latter belong the liver, the pancreas, and the spleen. The first process of digestion is the solution of the aliments. When the aliments, after being properly prepared, and mixed with saliva by mastication, have reached the stomach, they are inti- mately united, by the motion of the stomach, with a liquid sub- stance called the gastric juice. By this motion, the aliments are mechanically separated into their smallest parts; penetrated by gastric juice, and transformed into a uniform pulpy, or fluid mass. At the same time, a solution of the aliments into their simple ele- ments, and a mixture of them, so as to form other products, takes place, effected partly by the peculiar power of the stomach, and the liquid generated in it; partly by the warmth of this organ. This pulpy mass, called chyme, proceeds from the stomach, through the pylorus, into the part of the intestinal canal called the large intestines, where it is mixed with the pancreatic juice, and the bile. Both these liquids operate most powerfully on the chyme, yet in very different Avays. The mild juice of the pan- creas attracts the milk-like liquid of the chyme, and forms with it the chyle, which is absorbed by the capillary vessels called lacteals. On the other hand, the bitter matter called bile, formed by the liver from the blood, attracts the coarser parts, which are not fit- ted to be absorbed into the fine animal organization; and excites the intestinal canal to the motion Avhich carries it off, through the natural channel. CHAP. IV. RESPIRATION. Respiration ; the alternate inspiration and expiration of atmo- spheric air, for the purpose of bringing it in contact with the blood, and exchanging the hydrogen and carbon, with which it is charged, for oxygen. This function is, therefore, closely connected with that of the circulation of the blood. The organs and mechanism by which this wonderful function is carried on, vary considerably in the different classes of animals. In the mammalia, birds and reptiles, the organ of respiration is the lungs ; in fish, the gills ; in most common instruments, the trachea?; and, in the lower classes of animals, different parts of the system. The air, being brought in contact with the blood, is decomposed; its oxygen is united with the blood, and its nitrogen is returned, by expiration, unchan- ged, with an additional quantity of carbonic acid gas. A part of the oxygen of the inhaled air is united, in the lungs, with the free hydrogen, and forms water, which is emitted in the form of vapor, visible at 40° Fahrenheit. Another part of the oxygen unites with the superfluous carbon in the blood, and forms the carbonic acid gas which passes off with the watery vapor. It is evident, from ob- servation, that oxygen gas is necessary to animal life. As to its manner of operating in the body after inspiration, opinions differ. Upon respiration, also, depends animal heat, which is greater, at least, in mammalia and birds than that of the surrounding element. The mechanical part of the function of respiration is effected by the action of the ribs and diaphragm. In the natural state, the ribs are inclined downwards ; and when this series of movable hoops is raised by the action of the muscle, the cavity of the chest is en- larged. The descent of the diaphragm, by its construction, in- creases this effect, and the air, therefore, rushes in to fill up the va- cant space; the ribs then descend, and the diaphragm rises, and the air is necessarily driven out in consequence of the resulting 470 MISCELLANEOUS. contraction of the chest. About tAventy respirations take place in a minute ; and from thirty to forty cubic inches of air are inhaled at each inspiration. A man consumes about a gallon of air in this same time. PERSPIRATION. By perspiration from the skin of beasts and men, Ave understand first, the action by which certain fluid matters, separated from the blood in the thick network of capillary vessels and cells constitu- ting the skin, are changed into vapor, (or into fine effluvia,) and in this form escape at the pores of the skin; second, sometimes, also, the secretion and removal from the body of these matters themselves by the action of the skin. This effluvium is usually so fine that we cannot see it with the naked eye; hence, Ave call it the insensible perspiration; but it becomes a isible if Ave hold the hand on cold glass or polished metal, also, if the perspiration is strong, in a cold temperature, or if from a still stronger perspira- tion, this vapor is not dissolved in the air, but collects on the skin in drops forming sweat. This perspiration, through the skin, has much resemblance to the vapor that escapes from the lungs to the secretions of the membranes lining the cavities of the body, as the stomach, chest, and abdomen, with which secretions it also appears to stand in connection. The importance of this function will be evident when we reflect that the surface of a full grown man con- tains fifteen or sixteen square feet, and, therefore, the quantity of matter incessantly perspired must be very great, which is also con- firmed by the accurate observations of Sanctorius, (Venice, 1611,) who spent a great part of his life at the balance. He weighed and kept an account not only of all the food that he consumed, but also of every thing that passed from him, and thereby proved that a great part, not only of the fluids, but also of the solid substances that a man consumes, leaves his body by perspiration. Perspiration promotes two objects, very important for the pre- servation of the bodily structure; one is the purification of the blood from injurious and superfluous matters. Besides the adven- titious compound matters that pass into the blood from particular kinds of food, (for instance, onions, etc.,) the carbon, the hydro- PERSPIRATION. 471 gen, and particularly the excess of nitrogen, are carried off from the blood by perspiration, and changed by caloric into gas and va- por, and thus removed from the body. The substance of the body is, in many diseases, particularly in fevers, converted into aeriform fluids by an evaporation so extraordinarily increased and accelerat- ed, that the strongest man is entirely worn away in a few days, without having lost any thing except through the skin. The other advantage of perspiration is, the preservation of a suitable degree of warmth in the body, and the reduction of an immoderate heat. Every living body has its peculiar degree of warmth, which re- mains for the most part the same, whether the surrounding bo- dies are more or less Avarm. The temperature of man is about ninety-tAvo to ninety-nine degrees of Fahrenheit. As much caloric is employed in the process of perspiration, it is an important means of cooling the body, and of conducting off the heat which is incessantly generated within. The greater the heat which the body is exposed to, or the more it is produced Avithin from other causes, as hot drinks and excitement, the greater is the perspira- tion, and the more actively is the heat conducted off. If the body is exposed to great cold, the operations of the skin are weakened, perspiration proceeds more sloAvly, caloric is more sparingly con- sumed, and thus accumulates in the body. Men usually lose flesh in summer, and recover it in Avinter, because the increased perspi- ration dissolves and removes more substance from the body in the former season. Therefore a man is cooled by sweat, and in the dry heat of fever is refreshed, as soon as a crisis produces perspi- ration. An interruption, or even a disturbance of perspiration for a long time, must then produce results in the highest degree pre- judicial to the health, and even dangerous to life. These results, in a great measure, depend on the close connection of the opera- tions of the skin with those of the internal organs, and are the more stubborn and injurious the longer the perspiration is imped- ed. The increase of the internal warmth often produces a fever; also noxious matters are collected in the blood, from which it should be freed ; therefore, it changes from its natural condition, and an unnatural excitement is produced. Finally, the operation of the other organs of secretion is immoderately increased, because they have to perform, in part, the office of the skin; thence re- 472 MISCELLANEOUS. suit after a cold, rheum, sore-throat, cough; also serious internal inflammations, diarrhea, diabetes, dropsy, protracted rheumatism, and various other diseases. SECRETION. Many of the component parts of the animal system become, in the course of its operation, changed and unfit for further use. For the preservation of the system, it is not less necessary that these parts should be removed, than that the constant consumption should be supplied; and in this double process, the Avhole organic system is continualy changing its ingredients, although it retains the same external form. This supply of new matter is derived from the blood, and the process itself is called secretion. Most animals secrete both solids and fluids. The solids are deposited by the capillary vessels, at the places of their destination, and supply the continual wear of the system. The liquids are not intended to preserve the form directly, but serve to assimilate the food, by promoting digestion, as, for instance, the saliva, gastric juice, and bile. In these secreted fluids, are contained all the component parts of the blood, slightly changed, together Avith an alkali. Distinguished from these, are the excretions which are produced in a similar manner, and are designed to carry off from the system useless matter. SYMPATHY; The quality of the animal organization, by which, through the increased or diminished activity of one organ, that of others is also increased or diminished. The idea of an organized system— the union of many parts in one Avhole, in Avhich all the parts cor- respond to each other—includes the idea of a mutual operation, of Avhich sympathy is a part. The medium between the organ from which the action proceeds, and that to Avhich it extends, has been sometimes supposed to be the nervous system, sometimes the vascular or the cellular system, or the juices, and it cannot be denied, that, in some sympethetic phenomena, the nerves and CRISIS. 473 the vessels appear to be the media; but there are objections to considering them as the cause of sympathy in general, for exper- ience teaches that sympathy takes place also betAveen such organs as have no discoverable connection by nerves or vessels. The phenomenon of sympathy appears even in the healthy body; e. g. a strong light throAvn upon the eye, sometimes produces sneezing, (q. v.); tickling causes laughing; and some physiologists have even called the change of voice at the age of puberty, and the increased secretions of the liver, the salivary glands, the pancreas, and the coats of the stomach, at the time of digestion, a sympathetic ac- tion. But the effect of sympathy is much more oftener observed in diseases. There is hardly one in which some phenomena are not to be explained by sympathy. Sympathy is further used to ex- press the influence of the state of one individual upon another, e. g. the tickling in the throat, caused by the cough of another per- son, or the yawning produced by seeing another yawn, or the grief produced by Avitnessing his grief. The effects of animal magnetism (q. v.) are also ascribed to sympathy, and those which the sight of some animals is said to have upon some men. CRISIS. Crisis in medicine; a point in a disease, at which a decided change for the better or Avorse, takes place. The crisis is most strongly marked in the case of acute diseases, and Avith strong pa- tients; particularly if the course of the disease is not checked by energetic treatment. At the approach of a crisis, the disease ap- pears to assume a more violent character, and the disturbance of the system reaches the highest point. If the change be for the better, the violent symptoms cease, Avith a copious perspiration, or some other discharge from the system. In cases where the dis- charge may have been too violent, and the nobler organs have been greatly deranged, or Avhere the constitution is too Aveak to resist the disease, the patient's condition becomes worse. In regular fevers, the crisis takes place on regular days, which are called critical days; sometimes, however, a little sooner or 60 474 MISCELLANEOUS. later; according to the climate and the constitution of the patient. A bad turn often produces a crisis someAvhat sooner. When the turn is favorable, the crisis frequently occurs a little later. After a salutary crisis, the patient feels himself relieved, and the danger- ous symptoms cease. SOMNAMBULISM. Somnambulism designates the well knoAvn phenomena of sleep- Avalking. It is also used for a certain state of a person under the influence of animal magnetism, (q. v.) The phenomena of sleep-Avalking, are very singular; the person affected performing many voluntary actions, implying a certain de- gree of perception of the presence of external objects. This affec- tion is commonly considered as an imperfect degree of sleep. In the case of the somnambuli, says Dugald SteAvart, the mind retains its poAver over the limbs, but possesses no influence over its OAvn thoughts, and scarcely any over the body, excepting those particu- lar members of it which are employed in walking. Sleep-walking is not unfrequently connected with the changes of the moon; when people Avill rise, Avalk about, do certain things, and go to bed again. The placing of a wet cloth by the side of the bed of such a per- son, so as to Avake him immediately, when he steps on it, is re- commended as a means of curing this habit. The subject is very obscure, the cases not having been philo- sophically studied to a sufficient extent. As to somnambulism in animal magnetism, the votaries of this science believe that the brain, the peculiar seat of the higher faculties, rests during som- nambulism, but that the vital power of the nervous system of the abdomen is heightened so much, that it can supply, in a degree, the place of the brain, and afford the means of perception. Hence, a letter placed on the stomach of a person in the state of somnam- bulism, can be read by him. INJECTIONS. 475 INJECTIONS. Injections belong partly to surgery, and partly to anatomy. In surgery, fluids, different according to the different effects de- sired to be produced, are thrown, by means of a small syringe, into the natural cavities of the body, or those occasioned by dis- ease, partly to remove unhealthy matter, and partly to bring the remedy immediately to the seat of the disorder, and thus effect a cure. Wounds and sores are usually cleansed in this way, when they extend far beloAV the skin, or an excitement and cure are pro- duced by the same method. In diseases of the nose, and the cavities connected with it; in those which have their seat in the neck; in disorders of the ears, the bladder and urethra, the uterus and vagina, and for the radical cure of hydrocele, injections are often used, and with important advantages. Pure warm water is injected, with the highest suc- cess, for the removal of pus, blood, or even foreign bodies. Some- times astringent medicines, to restrain excessive evacuations; sometimes stimulating ones, to excite inflammation, as in hydro- cele, or even to increase and improve evacuations; sometimes soothing medicaments, to mitigate pain, etc., are added to the wa- ter. In diseases of the throat Avhich hinder the patient from swal- loAving, and thus tend to produce death by starvation, nourishing fluids are injected into the stomach. The blood of beasts, or of men, has been sometimes injected into the veins, which is called transfusion. In the same way, medicines are introduced immediately to the blood: for instance, tartar emetic, to excite vomiting, if a foreign body is fixed in the throat so firmly as to restrain the patient from swallowing, and can neither be moved up nor down. According to the place where the injection is to be made, the instrument must be either longer or shorter, a straight or a curved tube. The size is regulated by the quantity of the liquid to be injected, and the force which is to be applied. Anatomists inject into the vessels of bodies various colored fluids, which are liquid Avhen hot, and coagulate when cold, to make the smaller ones visible. Thus, the arteries, veins, and lymphatic vessels, are injected. Anatomy has carried this art so far, as to make very minute vessels visible to the naked eye. 476 MISCELLANEOUS. PREGNANCY. Pregnancy ; the state of a female who is Avith child. Preg- nancy begins at the moment of conception, and ceases with that of birth. During pregnancy, the vital activity, especially of the womb, Avhich probably receives, a few days after conception, the fecundated vesicle, increases; the periodical discharge of blood ceases ; but the vessels of the Avomb become enlarged, more charg- ed Avith blood, longer and straighter. Its cellular substance be- comes softer and more spongy, the sides thicker, the cavity Avider. It loses the pear shape Avhich it has Avhen not impregnated, and becomes more globular; it sinks, during the first two months of pregnancy, lower into the pelvis; but, afterAvards, rises and be- comes larger, until, in the eighth month, the bottom of it can be felt, externally, in the region of the stomach. In the ninth month it sinks again someAvhat. In these changes of the womb, the em- bryo developes itself, until it has reached, in the fortieth week, a sufficient degree of maturity to be able to live separate from the mother Avhen the birth takes place, and pregnancy is at end; but the vital activity is increased in the state of pregnancy, not only in the womb, but in the whole body, with healthy and vigorous women. Pregnant women are bolder, more independent, more enterprising, stronger than before, and retain these qualities when they are mothers. They are more rarely affected by contagious diseases ; consumption is checked during pregnancy, but makes more rapid progress after its completion. Hysteric Avomen feel often uncommonly well during this period; the gouty are freed from their attacks ; some become uncommonly fat. On the other hand, this state is, Avith many, particularly with feeble, delicate, sickly, too old, or too young Avomen, often accompanied by a great many complaints Avhich depend upon the altered state of the systems of the vessels and nerves. The stomach, particularly, often suffers ; hence nausea, vomiting, a morbid loathing of, or craving for, par- ticular dishes, which were, till then, indifferent. Pregnant women often suffer, also, by wandering pains, particularly in the teeth, and by coughing. Much inclination exists in the body to inflam- mation, and a heated state of the blood; the veins of the feet and PREGNANCY. 477 the posteriors are SAvelled. The mechanical pressure of the womb, thus changed in situation and form, not unfrequently causes irregu- larities in the discharges of the urine and excrements. All these changes serve as signs of pregnancy; other signs are the gradual and regular changes observed, at the opening of the womb, by in- ternal examination; also the state of the breasts, which become larger during pregnancy, and in which a milky substance collects, but particularly the change of color round the nipple; lastly, the motion of the child felt by the mother in the second half of the period of pregnancy, and the perception of different parts of the foetus by external and internal examination. It is very important to determine the fact of pregnancy at an early stage ; but it is very difficult in some cases, particularly in the first half of the period, because there are a number of diseases of the abdomen which are attended with similar symptoms. Pregnancy, itself, is subject to a number of deviations from the ordinary course. The rules laid doAvn to prevent injury to the embryo, and to preserve the health of the mother, have reference principally to air, nourishment, and exercise; to the natural desires, and preternatural longings, (the latter must be gratified with much caution;) to the passions which must be carefully restrained ; to the imagination, because the whole nervous system may easily become over-excited ; to the proper al- lowance of sleep and the disposition of dress, which must not press either the abdomen or the breast. All injuries from over-exertion or mechanical causes are to be carefully avoided, as falls, lifting, blows, etc., because they may easily occasion abortions. During pregnancy, care ought also to be taken that the breasts are fit, after the birth of the child, to nourish it. It is a mistaken idea that abortions take place much more frequently among the higher clas- ses ; the poorer classes, in populous cities, are quite as liable to them. In the country, where a purer air keeps the body always in a more vigorous state, abortions occur less frequently. The advice of experienced female friends, during the whole period of pregnancy, is, of course, of the greatest value; yet, in almost all countries, certain prejudices exist respecting this important state in a female's life, and the advice of a physician cannot be dispensed with. The internal examinations, mentioned above, are compara- tively rare in England and the United States ; but, in France, Ger- many, and Italy, if not throughout the European continent, they 478 MISCELLANEOUS. belong to the regular course of medical attendance in the state of pregnancy. If every Avoman, during the eighth and ninth month, would apply our Stimulating Liniment to the abdominal region once a day, to the amount of a half a thimble full, she Avould find invaluable benefit therefrom. The child Avould be more vigorous and healthy, the labor pains Avould be much diminished, and the risk of miscarriage would be entirely overcome. CHAP. V. IRRITABILITY. Irritability ; (irritabilitas, from irrato, to provoke; vis insi- ta of Haller; vis vitalis of Corter; oscillation of BoerhaaAre; tonic power of Stahl; muscular power of Bell; inherent power of Cullen;) the contractibility of muscular fibers, or a property peculiar to muscles, by Avhich they contract, upon the application of certain stimuli, without a consciousness of action. This poAv- er may be seen in the tremulous contraction of muscles when la- cerated, or when entirely separated from the body in operations. Even when the body is dead, to all appearance, and the nervous power is gone, this contractile power remains till the organization yields, and begins to be dissolved. It is by this inherent poAver that a cut muscle contracts, and leaves a gap; that a cut artery shrinks, and grows stiff after death. This irritability of muscle is so far independent of nerves, and so little connected Avith feel- ing, Avhich is the province of the nerves, that, upon stimulating any muscle, by touching it with caustic, or irritating it with a sharp point, or driving the electric spark through it, or exciting with the metallic conductors, as those of silver or zinc, the muscle instantly contracts, although the nerve of that muscle be tied: al- though nerves be cut so as to separate the muscle entirely from all connection with the system; although the muscle be separated from the body ; although the creature, upon Avhich the experi- ment is performed, may have lost all sense of feeling, and have been long apparently dead. Thus a muscle, cut from the limb, trembles and palpitates a long time after; the heart, separated from the body, continues its peristaltic motion, so as to roll upon the table, ceasing to ansAver to stimuli, only Avhen it becomes stiff and cold. Even in vegetables, as in the sensitive plant, this contractile power lives. Thence comes the distinction between 480 MISCELLANEOUS. the irritability of muscles, and the sensibility of nerves ; for the irritability of muscles survives the animals, as Avhen it is active af- ter death : survives the life of the part, or the feelings of the Avhole system, as in universal palsy, Avhere the vital motions continue entire and perfect, and Avhere the muscles, though not obedient to the Avill, are subject to irregular and violent actions ; and it sur- vives the connection with the rest of the system, as Avhen animals very tenacious of life, are cut into parts : but sensibility, the pro- perty of the nerves, gives the Ararious modifications of sense, as vision, hearing, and the rest; gives also the general sense of pleasure or pain, and makes the system, according to its various conditions, feel vigorous and healthy, or Aveary and Ioav. The eye feels and the skin feels ; but their appointed stimuli produce no motions in these parts ; they are sensible, but not irritable. The heart, the intestines, the urinary bladder, and all the mus- cles of voluntary motion, answer to stimuli with a quick and for- cible contraction; and yet they hardly feel the stimuli by which these contractions are produced; or at least they do not convey that feeling to the brain. There is no consciousness of present stimulus in those parts Avhich are called into action by the impulse of the nerves, and at the command of the will; so that muscular parts have all the irritability of the system, with but little feeling; and that little oAving to the nerves which enter into their sub- stance ; Avhile nerves have all the sensibility of the system, but no motion. After every action in an irritable part, a state of rest, or cessa- tion from motion, must take place, before the irritable part can be again incited to action. If, by an act of volition, Ave throAV any of our muscles into action, that action can only be continued for a certain space of time. The muscle becomes relaxed, notwithstan- ding all our endeavors to the contrary, and remains a certain time in that relaxed state, before it can be again throAvn into action. Each irritable part has stimuli Avhich are peculiar to it, and Avhich are intended to support its natural action ; thus blood is the sti- mulus proper to the heart and arteries; but if, by any acci- dent, it gets into the stomach; it produces sickness or vomit- ing. The urine does not irritate the tender fabric of the kindeys, ureters or bladder, except in such a degree as to preserve their healthy aetion ; but if it be effused into the eellular membranes, it IRRITABILITY. 481 brings on such a violent action of the vessels of these parts, as to produce gangrene. Such stimuli are called habitual stimuli of parts. Each irritable part differs from the rest in regard to the quantity of irritability which it possesses. This law explains to us the reason of the great diversity which we observe in the ac- tion of various irritable parts ; thus the muscles of voluntary mo- tion can remain a long time in a state of action ; and if it be con- tinued as long as possible, another considerable portion of time is required, before they regain the irritability they lost; but the heart and arteries have a more short and sudden action, and their state of rest is equally so. The circular muscles of the intestines have also a quick action and short rest. The action of every stimulus is in an inverse ratio to the fre- quency of its application. A small quantity of spirits, taken into the stomach, increases the action of its muscular coat, and also of its various vessels, so that digestion is thereby facilitated. If the same quantity, however, be taken frequently, it loses its effect. In order to produce the same effect as at first, a larger quantity is ne- cessary ; and hence the origin of dram-drinking. The more the irritability of a part is accelerated, the more that part is disposed to be acted upon. It is on this account that the activity of all ani- mals, while in perfect health, is much livelier in the morning than at any other part of the day ; for, during the night, the irritability of the Avhole frame, and especially that of the muscles destined for labor: viz. the muscles for voluntary action, is re-accumulated. The same law explains why digestion goes on more rapidly the first hour after food is swallowed, than at any other time ; and it also accounts for the great danger that accrues to a famished per- son upon first taking in food. In German philosophy, irritability, sensibility, and reproduc- tivity, constitute the whole of organic life. Since the time of Schelling, irritability is much considered in the mental philosophy of that country. The French, treating the subject merely with reference to physiology, generally use, at present, the word con- tractility, instead of irritability: 61 482 MISCELLANEOUS. CLINICAL MEDICINE. Clinical medicine teaches us to investigate at the bed-side of the sick, the true nature of the disease, in the phenamena present- ed ; to note their course and termination; and to study the effects of the various modes of treatment, to Avhich patients may be sub- jected. From this mode of study Ave learn the character of indi- vidual cases; theoretical study being competent to make us ac- quainted Avith species only. Clinical medicine demands, there- fore, careful observations. It is, in fact, synonymous with expe- rience. What advances Avould medicine have made, and from how many errors would it have been saved, if public instruction had ahvays followed this natural course, so that pupils had received none but correct impressions, and distinct conceptions of the phe- nomena of disease, and had attained a practical knowledge of the application of those rules and precepts, which dogmatical instruc- tions always leave indefinite! We are unacquainted with the method of clinical instruction in medicine, Avhich was followed by the Asdepiades, but we cannot help admiring the results of it, as exhibited to us in the Avritings of Hippocrates, who augmented the stores of experience inherited from them, by folloAving in their steps. After his tim6, medicine ceased to be the property of particular families, and the path of experience, by which it had been rendered so valuable, was soon deserted. The sIoav process of anatomy and physiology, the almost constant study of the philosophy of Aristotle, and the endless disputes respecting the nature of man, of disease, and of remedies, occupied all the attention of the physicians; and the wise method of observing and describing diseases themselves, fell into disuse. Hospitals, at their vigor, served rather as means of displaying the benevolence of the early Christains, than of perfecting the study of medicine. The school of Alexandria Avas so celebrated, according to Ammianus Marcellinus, that a careful attendance upon its lessons, entitled the student to pursue the practice of medicine. Another old, and very thriving, although less known institution, was situated at Nisapour, in Persia; and hospitals, even before the flourishing period of the Arabians, to whom the happy idea is commonly ascribed, were united with CLINICAL MEDICINE. 483 these medical institutions. The. last school, founded by the em- peror Aurelian, and superintended by Greek physicians, spread the doctrines of Hippocrates through all the East. It Avas sup- ported for several centuries, and in it, Avithout doubt, Rhazes, Ali Abbas Avicenna, and the other celebrated Arabian physicians, were instructed. At the same time, the celebrated John Mesne, of Damascus, was at the head of the hospital of Bagdad. Of the mode of instruction pursued there, Ave know nothing, but we are inclined to form no very elevated opinion of the systems of an age which Avas devoted to all the dreams of Arabian polyphar- macy. In truth, medicine shared the fate of all the other natural sciences in the barbarous ages. Men were little disposed to ac- quire, sloAvly and cautiously, the knowledge of disease, at the bed-side of the sick, in the manner of the Greek physicians. It appears probable, that the foundation of universities led to a renewed attention to the study of medical science; and Ave find, accordingly, that in Spain, even under the dominion of the Ara- bians, there were schools and hospitals, for the instruction of young physicians, at Seville, Toledo, and Cordova. But even then, clinical studies were almost Avholly neglected. Instead of studying the history of diseases, the pupils occupied their time Avith the most unprofitable pursuits. Not much more advanta- geous Avere the journeys which were made, for the same objects, to Italy and France, in the eleventh and twelfth centuries. The schools of Paris and Montepelier were those principally resorted to; but in these, the instruction consisted simply of lectures, and endless commentaries upon the most obscure subjects; and even at the close of the fifteenth century, when the works of the Greek physicians began to be printed, men Avere still busied with verbal explanations and disputes. Two centuries elapsed before physi- cians returned to clinical studies and instructions. Among the renovators of this mode of studying medicine, may be named, in Holland, William Von Straten, Otho Heurnius, and the celebrated Sylvius, about the middle of the seventeenth century; and it is said that clinical instruction was given, at the same period, in the schools of Hamburg, Vienna, and Strasburg. Even Boer- haave, Avho succeeded Sylvius as clinical instructor at Leyden, in 1714, has left us no journals of daily observations of disease, but only academic discourses upon the general principles of medicine. 4S4 AIISCELLANEOUS. The influence of this celebrated school Avas first perceived at Ed- inburg, and afterwards at Vienna, tAvo schools, which, in celebrity for clinical instructions, soon eclipsed their common mother, the school at Leyden. Cullen, one of the most celebrated teachers of practical medicine at Edinburg, Avas too fond of fine-spun theories upon the condition of the disease, structures of the body, and the proximate causes of disease, to follow a uniform method in his lectures, and to adopt the entire history of disease, as observed at the bed-side, as the basis of his system. From the account of Avhat was effected in clinical medicine in Italy, Germany, and France, in the course of the eighteenth cen- tury, we may discover both the constantly increasing attention to this department of knoAvledge, and the difficulties with Avhich such institutions are obliged to contend. The Vienna school, by means of the labors of Van SAvieten, De Haen, and, still more, of Stolt and of Franck, became a model of clinical study, since public lectures Avere given in the hospital, and the simplicity of Grecian medicine successfully inculcated. The practice and study of me- dicine, in the hospitals in France, was only an indirect mode of gaining public confidence, till the period of the general revival of science, and the erection of the French Ecole de Sancte. In that, for the first time, clinical instruction Avas expressly commanded. At the present day, every good school has its establishment for clinical medicine connected Avith it; that is, a hospital, in which diseases can be seen and studied by those attending it. In Germany, the empirical, or experimental mode of studying medicine, was early given up for the more scientific form of lec- tures ; while in England and France, the opposite extreme took place, and students Avere carried, as they sometimes are still, to the bed-side of the sick, before they had been properly grounded in elementary studies. In Germany, there are very numerous journals, Avhich contain clinical reports of cases, as there are so many clinical institutions appropriated to particular classes of dis- ease. In the American schools, clinical instruction is almost wholly overlooked, although some slight lectures of this descrip- tion are given by the physicians of hospitals. The clinical school is called ambulatory, when the patients attend only at particular hours; and it is termed polyclinic, Avhen the instructor and his pupils visit together the beds of the sick. CONTAGION. 4S5 CONTAGION. This word properly imports the application of any poisonous matter to the body through the medium of touch. It is applied to the action of those very subtile particles arising from putrid sub- stances, or from persons laboring under certain diseases, Avhich com- municate the disease to others; as, the contagion of putrid fever, the effluvia of dead animal or vegetable substances, the miasmata of bogs and fens, the virus of small-pox, lues venera, etc., etc. The principal diseases excited by poisonous miasmata, are, in- termittent, remittent, and yelloAV fevers, dysentery, and typhus. The last is generated in the human body itself, and is sometimes called the typhoid fomes. Some miasmata are produced from moist vegetable matter, in some unknown state of decomposition. The contagious virus of the plague, small-pox, measles, chincough, cynanche maligna, and scarlet fever, as well as of typhus and the jail fever, operates to a much more limited distance through the medium of the atmosphere, than the marsh miasmata. Contact of a diseased person is said to be necessary for the communication of plague, and an approach within two or three yards of him, for that of typhus. The Walcheron miasmata extended their pesti- lential influence to vessels riding at anchor, fully a quarter of a mile from the shore. The chimical nature of all these poisonous effluvia is little un- derstood. They undoubtedly consist, however, of hydrogen, uni- ted with sulphur, phosphorus, carbon, and azote, in unknown pro- portions and unknown states of combination. The proper neu- tralizers or destroyers of these gasiform poisons are, nitric acid vapor, muriatic acid gas, and chlorine. The two last are the most efficacious, but require to be used in situations from which the patients can be removed at the time of the application. Nitric acid vapor may, however, be diffused in the apartments of the sick, without much inconvenience. Bed-clothes, particularly blan- kets, can retain the contagious fomes, in an active state, for almost any length of time. Hence, they ought to be fumigated, with pe- culiar care. The vapor of burning sulphur or sulphurous acid, is 4S6 MISCELLANEOUS. used in the East, against the plague. It is much inferior in power to the other antiloimic reagents. There does not appear to be any distinction commonly made between contagious and infectious diseases. The infection com- municated by diseased persons, is usually so communicated by the product of the disease itself; for instance, by the matter of the small-pox; and, therefore, many of these diseases are infectious only when they have already produced such matter, but not in their earlier period. In many of them, contact Avith the diseased person is necessary for infection, as is the case with the itch, syphilis, and canine madness; in other contagious diseases, even the air may convey the infection; as in the scarlet fever, the mea- sles, the contagious typhus, etc. In this consists the whole differ- ence between the fixed and volatile contagions. A real infection requires always a certain susceptibility of the healthy individual; and many infectious maladies destroy, forever, this susceptibility of the same contagion in the individual, and, accordingly, attack a person only once, as the small-pox, measles, etc. Other conta- gious diseases do not produce this effect, and may, therefore re- peatedly attack the same persons; as typhus, itch, syphilis, and others. Sometimes one contagious disease destroys the suscepti- bility for another; as the kine-pox for the small-pox. In general, those parts of the body Avhich are covered Avith the most delicate skin, are most susceptible to contagion; and still more so are wounded parts deprived of the epidermis. Against those contagious diseases which are infectious through the medium of the air, precaution may be taken by keeping at the greatest pos- sible distance from the sick, by cleanliness, and fearlessness; but most completely by the vigilance of the health officer, by fumiga- tions according to the prescriptions of Guyton Morvea, etc. We can more easily secure ourselves against such contagious diseases as are infectious only in case of contact, by means of cleanliness, caution in the use of vessels for eating and drinking, of tobacco- pipes, of Avind-instruments, beds and clothes. No general preser- vative against contagious diseases is known, though many are of- fered for sale by quacks. The examination of the persons inten- ded for nurses and tenders of infants is very necessary, as thou- sands of children may be infected by contact with them, and the cause of the disorder remain unknown. ANTIDOTES. 487 ANTIDOTES. Antidotes, from two Greek Avords, signifying given against; the means of counteracting the effects of poisons. The term anti- dote had, formerly, a much wider signification, and was applied to the remedies for diseases occurring from natural causes, as well as to the remedies for the derangement of the functions arising from the direct introduction into the system of a knoAvn and material poison. Doubtless every disease may be looked upon as spring- ing from some poison, as fevers from an altered and unhealthy state of the atmosphere, or eruptive and contagious diseases from the vitiated fluids or breath of one individual communicated to an- other, as small-pox and hooping-cough. This opinion is expres- sed by the employment of the term virus, or poison, to signify the immediate cause of such diseases, as when we speak of the small-pox virus, or the vaccine virus. But as, in the present day, the word antidote is used only to signify the means of counteract- ing the effects of poisons, strictly so called, we shall confine our observations to what is properly comprehended under the term Avhen employed in this sense. While thus limiting its significa- tion, it is equally necessary that we should limit the application of the word poison. It is, however, extremely difficult to define what a poison is. Fodere considered poisons to be those substances known to be capable of rapidly altering or dertroying some or all of the functions necessary to life. This must be understood to ap- ply to their introduction (whether accidentally, intentionally on the part of the person suffering, or criminally on the part of others) into the body when in the usual state of health ; for there are cer- tain diseased conditions of the systems which seem to render it in- capable of being injuriously affected by doses of medicines Avhich at another time would speedily destroy life; and other states, such as when the body is under the influence of one poison, where an- other proves the most effectual remedy or antidote. This latter state is strikingly exemplified in the case of the bite of the coluber carinatus, a species of snake common in the West Indies, during the state of stupor or insensibility occasioned by which, a large quantity of arsenic may be given, not only with safety, but with 488 MISCELLANEOUS. such advantage that the recovery of the patient may be considered as OAving solely to it. To acquire a correct idea of the different Avays in Avhich poisons operate in destroying life, Ave must be made aAvare that Avhat we commonly regard as an individual is made up of a number of distinct organs, which, though in some respects in- dependent of each other, yet exert a reciprocal influence, the har- monious play of the whole being necessary to the continuous exer- cise or display of the principle of life, and that a cessation of the functions of any one of the more important organs necessitates the successive suspension of the rest. The most essential of those are consnquently denominated the vital functions, viz: the circula- tion, respiration, and enervation. The circulation of red or arterial blood through the system, but especially through the nervous matter of the brain and spinal cord, is essential to the existence of the vital properties and due perform- ance of the functions of the different organs—which circulation is effected by the action of the heart; while, to render the blood ar- terial, respiration is necessary ; and this is effected by the lungs, assisted by a great number of muscles, the co-operation or simul- taneous action of which is occasioned by the influence of the spinal cord directed or influenced by the brain. Noav, certain poisons act either solely on one of the organs and functions or upon two or three, but ahvays in an ascertained order or uniform succession. Oxalic acid, (or the acid of sugar, as it is properly called,) for ex- ample, in a small dose, acts first on the brain and spinal cord; but, in a larger dose, also affects the heart. In the former case, the respiration will be perceptibly interfered with, while the heart will go on acting, for some time; in the latter case, both will cease at the same moment. Recovery, therefore, is much more probable in the first instance than in the second, for we can carry on artifi- cial respiration till the brain and spinal cord have resumed the ex- ercise of their functions; but if, as in the second instance, the heart also has ceased to act, recovery is impossible. An arrangement of poisons, according to their mode of action, i. e. according to the order in which the vital functions are suc- cessfully affected and destroyed by them, would be of great utility in regulating our treatment, teaching us when to be content with the employment of antidotes alone, and Avhen to employ supple- mentary means—as artificial respiration, blood-letting, etc. At ANTIDOTES. 489 present we can only make an approximation to such an arrange- ment. Another point of consequence is the settlement of the ques- tion, do poisons act solely on the sentient extremities of the nerves of the part to which they are applied, and influence remote organs, only by sympathy : or are they absorbed into the circulatory flu- ids, and by them carried to the organs whose impaired or suspen- ded functions show them to be markedly affected by them ? With- out entering into this dispute, it may be stated that some poisons act in the one way, some in the other Avay, and a feAV in both. Of these, the first set are the most formidable and the most speedy in their action, allowing little time for the employment of antidotes. Some poisons act, but with different degrees of violence and speed, whatever part of the body they are applied to; others again, only when received into the stomach or intestines; while some, such as the poison of the viper, are quite powerless when swallowed. Of all parts of the body, the brain and nervous substances are the least susceptible of the action of poisons, when applied else- where. With respect to the local operation of poisons, i. e. their direct action on the part to which they are applied, some decom- pose chimically, or alter the structure of (corrode) the part which they touch, and hence they are called corrosive poisons; such are the mineral acids of which sulphuric or oil of vitriol may serve as an example. Besides this local effect, many of the corrosive poisons act speedily upon remote organs, the impaired functions of which may become a source of greater danger than the destruc- tion of the part first attacked. Other poisons, without immedi- ately altering the structure of the part, irritate it so that inflamma- tion ensues, by which it is altered, and the general system affect- ed as it would be by inflammation of the same part arising from any other cause, even when the poisonous substance does not pro- duce any immediate or powerful effect upon a remote organ— which is not often the case, as most of them influence some of the vital functions, and thus prove fatal. Those are termed irritant poisons, such as arsenic; but they are frequently also termed cor- rosive, though inaccurately. Lastly, there are poisons which nei- ther corrode nor irritate the part, but cause a peculiar impression upon the sentient extremities of the nerves, which is conveyed along these to some remote organ or organs, the functions of which 62 490 MISCELLANEOUS. they impair and suspend. Many of these should be termed seda- tives, in the strictest sense of the Avord ; others are narcotics ; and those Avhich produce some degree of local irritation, are termed narcotico-acrids. But one and the same article, according to the dose and mode of administration, acts in all the three Avays ; to- bacco for example. The selection of appropriate means to coun- teract the effects of poisons, must be determined by a knowledge of the manner in Avhich each particular poison acts; but, as we cannot enumerate or specify these here, Ave shall give only general rules to this effect. These may be reduced to three, viz. 1st, To remove the poisonous substance. 2nd. To prevent or limit its local effect. 3d. To obviate its effect on remote organs, support- ing their action by appropriate measures, till the injurious impres- sion has subsided. The first of these is to be accomplished most- ly by mechanical means. If the poison has been applied to any external part, as by the bite of a viper or a rattle-snake, a cupping glass, or what will ansAver as Avell, a wine-glass, tumbler, or cup of any kind, from which a part of the air has been expelled, by holding Avithin it a lighted candle for a second of time, should be immediately applied. If the poison has been taken into the sto- mach, and is yet of a kind to arrest instantly the action of the heart, its removal is to be attempted by the stomach-pump, or by exciting vomiting. The stomach-pump cannot well be used with- out introducing into the stomach a considerable quantity of water, which, by diluting the poison, lessens its violence, in all cases, except that of oxalic acid. The stomach-pump is also to be pre- ferred in the case of narcotic poisons, as the insensibility which they occasion prevents the stomach from being affected by emetics. But, should a stomach-pump not be at hand, nor any one be pre- sent skilled in the use of it, we must attempt to produce vomiting by every means in our power. For this purpose, a table spoonful of flour of mustard, which is mostly to be found in every house, may be put into a tumbler of warm water and given to the patient, or a.scruple of sulphate of zinc, (whetto-vitrio,) dissolved in a pint of any distilled water ; or ten grains of sulphate of copper dissolved in half a pint of any dis- tilled water, as cinnamon, may be drank by the patient, and the disposition to vomit encouraged, by tickling the throat with a fea- ther, and pressing on the pit of the stomach. ANTIDOTES. 491 Neither ipecacuanha nor tartar emetic should be given, as their action is always preceded by much nausea, during which the ab- sorption of the poison is often facilitated. Where the poison is of a corrosive or irritant nature, instead of losing time in seeking the means of causing vomiting, it is in general advisable to adopt the second rule, and attempt to prevent its local, and thereby its remote effects. To accomplish this, we must ascertain what the poisonous sub- stance was from which the patient is suffering, and must also know hoAV it acts, as upon this depends the success of our treatment. The objects we have in view are either to dilate and so weaken it as to supply, from an external source, the particular principle which the poison would subtract from the coats of the stomach, or by adding something to it, and so change its nature as to render it comparatively, or altogether harmless, which last will always be effected if we can succeed in forming an insoluble compound. The first may be done by giving plenty of warm Avater; and when we know the particular poison, if the warm water can be made the vehicle of an antidote, the second or third object will also be ensured. Suppose sulphuric acid (oil of vitriol) has been swallow- ed, add to the water, chalk, magnesia, or soap; the chalk will make, without the acid, sulphate of lime, Avhich, being insoluble, will do no harm, Avhile, with the magnesia, the acid will form sul- phate of magnesia, (Epsom salt,) and, with the soap, sulphate of potash, both of Avhich are purgative salts, and will, by their action on the bowels, assist in lessening the inflammation caused by the poison before it was decomposed. So when sugar of lead (acetate of lead) is swallowed, by giving Epsom salts, Ave form an inso- luble sulphate of lead, which will be discharged by the bowels, operated upon by the magnesia, Avhich has been freed from sul- phuric acid. Corrosive sublimate (chloride of mercury) abstracts from the coats of the stomach the albumen Avhich they contain, by which it is converted into proto chloride, or calomel; now, if by giving white of an egg, which is pure albumen, we supply it with the principle which it Avould otherwise obtain from the coats of the stomach, we shall preserve these entire. Such means, then, are antidotes, properly speaking ; for the means by which the se- condary or remote effects are to be combatted, deserve rather to be termed counter poisons. The counter poisons are of no small 492 MISCELLANEOUS. value in cases of poisoning by the corrosive and irritants, Avhile they are of the utmost importance in the treatment of the sedative and narcotic poisons. To administer these appropriately, we must know Avhich of the vital organs the poison most speedily af- fects. When it affects the heart, the symptoms greatly resemble syncope, (or fainting;) and, as such poisons are the most danger- ous, agents Avhich act as rapidly as the poisons are alone to be trusted to ; such agents are to be found among the diffusible stimu- li; ammonia, or its carbonate, i. e., smelling salts, applied to the nostrils, or dissolved in water and taken into the stomach ; warm brandy and Avater, etc., Avhere it chiefly affects the spinal marroAv, there occur spasms and difficulty of breathing; and, when the brain, there is a partial or complete insensibility, (coma,) often with, at first, full pulse, flushed face, and labored breathing, re- sembling apoplexy. In such a state of affairs, artificial respira- tion, and afterwards bleeding, with the subsequent administration of coffee or vinegar, greatly contribute to save the patient. We have not spoken here of gaseous poisons, which would lead to un- necessary details. They act either by excluding the common at- mospheric air, in which case removal into pure air is required, or by producing inflammation like the irritant, or oppression of the brain like the narcotic poisons, and are to be combatted on similar principles. It will be more useful to append a list of the poisons which act on the brain, and of those which act on the heart. Of poisons which act upon the brain, the most common are alcohol, i. e., spirituous liquors, opium, henbane, hemlock, camphor, and essential oil of almonds, and of tobacco. Of those acting on the heart, the chief are infusion of tobacco and large doses of Prussic acid, fox glove, strychnia, (principle of nux vomica,) oxalic acid, arsenic, preparation or salts of antimony and of baryta, and seve- ral animal poisons. From what has been said on this subject, the great necessity of an acquaintance with it must be sufficiently clear not only to en- sure our doing right, but to prevent us from doing wrong. By administering an ill-timed antidote, (as we conceive it to be,) we often hasten the fatal event; as Avhere vinegar is given, when opium has been swallowed, before it has been ejected from the stomach; and, by throwing tobacco smoke into the stomach of a person apparently drowned, we extinguish the feeble spark of life NUTRITION. 493 which might have sufficed to reanimate him but for such injudi- cious interference. It is to be hoped that more just principles of treatment will be diffused among the people, as well as among medical men, by which many lives may be preserved to their fa- milies and to the community. ANIMAL AND VEGETABLE NUTRITION. Animal and vegetable matters constitute the food of animals and vegetables ; yet these matters nourish neither the animal nor veg- etable, until they have undergone certain preparatory processes, and are reduced to a fluid state. Solid substances, so long as they remain solid, can benefit neither. The soil is to plants Avhat the stomach is to animals—the recip- ient of food—where it undergoes its first process of preparation, is broken down and blended with a solvent liquid. The spongeoles, or small roots of the plants, like the lacteals of the animal, take up the digested food, and send it to the leaves, as the lacteals do the lungs, for its perfect preparation as food. Leaves are to plants what lungs are to animals—the organs of respiration. The lungs retain oxygen, and give off carbon. The leaves part with oxygen, and inhale carbon Avhen the sun shines upon them, and imbibe oxygen when it does not. Leaves are, in summer, as necessary to the health and growth of the vegetable, as lungs are to the health and growth of the animal. Heat, air, and water are essential in all the processes of nutri- tion, vegetable as well as animal. The ordinary temperature of the animal stomach is 98 degrees— hence animal digestion does not abate for want of heat. The de- composition of vegetable food, in the soil, ceases when the ther- mometer sinks below 40 degrees, and is most active at the tempera- ture of 80 degrees. Neither lungs nor leaves can perform their office healthfully, without access to fresh air, nor can decomposition take place with- out air. Water is a necessary solvent in the preparation of vegetable and animal food for the delicate mouths of the lacteals and spongeoles, and is no less indispensable as a medium of transmitting the food 494 MISCELLANEOUS. to the lungs and the leaves, and from thence through the animal and vegetable structures. After the blood of the animal has been perfected in the lungs, it is conducted, by minute arteries, to every part of the body, and is transmuted into flesh, etc. After the sap has been elaborated in the leaves, it is conveyed, in like manner, to every part of the plant, and is then converted into wood, fruit, etc. Vegetables, like animals, may be injured by an excess of food; and when food is too concentrated, or too rich, the lacteals and the spongeoles become clogged, and unfit to transmit aliment to the lungs or leaves. A seed may be compared to an egg. One contains the germ of a chick, the other the germ of a plant. Nature has provided in their envelopes, the food proper for both, in infancy, and until they can provide for themselves. Through the agency of heat and air, the chick becomes animated, groAvs, and bursts its shell; and the seed germinates, grows, and bursts the earth. Both seem to require the exclusion of light. The elementary matters found in animals and vegetables are nearly the same—the animal contains the most nitrogen, the vege- table the most carbon. Lime and iron are found in both. And in both, the power and the habit exist, of throwing off, through their excretory organs, matters blended with their food, not fitted to their wants, or not assimilating Avith the elements of their structure. Plants often exhale, or give off, like some ani- mals, a strong odor. As weeds are more commonly natural to the soil than cultivated crops, they are grosser feeders, and consume more food than the latter. Hence, they should not be permitted to rob the crops. SALINE BATH. The Saline Bath has lately been brought into pretty extensive use, by a number of physicians who have adopted our remedies, Avith the most salutary effect. In chronic diseases, where the sys- tem has become morbid, and Avhere the liniments are not brought into full operation by the usual application, the Saline bath is found to answer a most valuable purpose. The mode of prepar- GALVANISM. 495 ing it is as follows: Warm the water, and add salt enough to make a common brine, and fill a bathing-tub two-thirds full; let it be as hot as the patient can bear; immerse the patient, and use the flesh-brush and friction with the hand freely while so im- mersed, which may be continued from five to fifteen minutes, ac- cording to the strength of the patient; then wipe dry with flannel, and apply the liniment over the whole surface of the body. Much benefit has also been gained by a similar process in cases of fever and bilious cholic, rheumatisms, cramps, etc. APPLICATION OF GALVANISM TO POI- SONED WOUNDS. In Germany, a variety of experiments have been made, proving the successful application of galvanism, in place of caustics, to poisoned Avounds. We shall mention some of them:— 1. A dog had lately been bitten by a mad one, in the chest, causing a Avound of two inches. After a lapse of fifty-four hours, the wound having dried up, it was for half an hour exposed to the influence of a galvanic battery of forty small plates. This appli- cation seemed to cause considerable pain, and produce the dis- charge of some blood from the Avound; subsequently a thick crust formed on it, which fell off on the eleventh day; on the sixteenth day, the wound was completely healed, and the dog remained Avell. 2. The poisonous saliva of the dog which had inflicted the above wound, was inoculated in both legs of another dog. After the lapse of fifty-four hours, galvanism was applied to the wound caused by the inoculation; the crust formed over it fell off on the eigth day, on the twelfth day it perfectly healed, and the dog kept well. 3. Another dog, inoculated with the same saliva as the last, was left to his fate, and died within ten days, of hydrophobia. From these and similar experiments, Doctor Peavaz draws the following results: 1. Because he was still successful after an interval of fifty-four hours, physicians have sufficient time, in case of accident, to pro- cure a galvanic battery. 496 MISCELLANEOUS. 2. As the galvanic fluid operates also at some distance, he ad- vises its application also to deep wounds with fistulas, notwith- standing the application of caustics. 3. That, by its peculiar nature, galvanism affords the advantage of destroying the poison even at some distance, and that it greatly counteracts absorption, by causing a contraction of the capillary vessels. GRANULATION. The little grain-like fleshy bodies which form on the surfaces of ulcers and suppurating wounds, and serve both for filling up the cavities and bringing nearer together and uniting their sides, are called granulations. Nature is active in bringing parts whose disposition, action, and structure, have been altered by accident or disease, as nearly as possible to their original state ; aud after hav- ing, in her operations for this purpose, formed pus, she immedi- ately sets about forming a new matter upon surfaces in which there has been a breach of continuity. This process has received the name of granulating, or incarnation. The color of healthy granulations is.a deep florid red. When livid, they are unhealthy, and have only a languid circulation. Healthy granulations on an exposed or flat surface, rise nearly even with the surface of the surrounding skin, and often a little higher; but when they exceed this, and assume a growing disposition, they are unhealthy, soft, spongy, and without any disposition to form skin. Healthy gra- nulations are always prone to unite. In all cases Avhere the wounds above mentioned produce an un- healthy pus, or are inclined to fungus flesh, our Stimulating Lini- ment, applied directly to the wound, though severe at first, is an invaluable application. It uniformly produces a healthy action, and expedites a cure. HEREDITARY DISEASE. The influence of the parents on the organization of the child is so great, that even the individual peculiarities which distinguish HEREDITARY DISEASE. 497 one man from another, are, in part at least, transmitted to his chil- dren ; hence the similarity in person and looks of the child to its parents. The internal organs, too, as Avell as the external form, have the same resemblance; so that the peculiar constitution, the greater or less activity and development of these organs, are found to pass from parent to child. Now, as it is the particular state of the several organs and functions in Avhich a very great part of dis- ease have their foundation, it folloAvs, that these diseases may be inherited, and, in fact, it has been observed, that the son is not unfrequently attacked by a disease, at the same period of life in which his father Avas. These diseases are called hereditary; but it is only the predisposition to them that is, properly speaking, in- herited. Hence the actual development of hereditary disease re- quires certain co-operating circumstances. Constitutional disease* are very often not hereditary, but depend on circumstances T/Hich affect the foetus during pregnancy. The father has no inflMtince on the child, beyond the act of generation; the moth-* operates upon it during pregnancy, and it is possible that *ere ^ occasion may be given to hereditary disease. Amorr "' lseases w ich are most frequently hereditary, are sr"'ula' Ceding, hemorr- hoids, consumption, gout, the gr»f and St°ne> scirrhous and cancers, disorders of the mind ^d sPirits' hysterical and hypo- chondriac affections, apopley' epilepsy, and organic diseases of particular parts, especial^the heart. They have this pecu- r 't th t tti t- educed, and appear as constitutional dis- c Ae action of internal than of external, of pre- eases, more from . ' r ,. Al a occasional causes. Such diseases are much disposing than .. ~ , to reach and to cure, than those Avhich originate in more dime . TT . . . „ . -. 1 external causes. Hence it is especiallv necessary to ncciclcrii" * in season their growth and development. The means of prev Ag this, are the following : 1. Whoever has a hereditary predisposition to any disease, should not marry one Avho has the same constitution. For this reason, marriages between near relations are not advisable, as tend- ing to perpetuate such hereditary diseases. This, too, appears to be the reason Avhy attachments are generally formed between per- sons of opposite constitution and different temperament. 2. We ought to order all the circumstances in which the child 63 498 MISCELLANEOUS. grows up in such a way that the inherited predisposition may not only not be favored, but counteracted. 3. The accidental occasions Avhich favor the groAvth of the dis- ease, should be avoided, especially at the time of life in which the father was attacked by it. The medical treatment of hereditary diseases is not essentially different from that Avhich is requisite in the same diseases arising under different circumstances. HISTORY OF THE SMALL POX. Of the numerous diseases to which mankind are exposed, the class denominated epidemic, or spreading diseases, is attended ^ith the most alarming interest. A malady of this sort may take lts origin in the remotest district of an extensive country, and yet, it its t-ogifess be independent of the peculiarities of soil and cli- mate, 1 m^j soon come t0 overrun the whole. In the same way, although a spreei{^ malady commence in one hemisphere of the globe, it may, after a ^ inyade the Qthe]% and hg ravages know ultimately no bound, sav.iW of human intercourse? and human existence. Those spreading ^^ from ^ ^ hayoc they often commit, have been con,.^ knQwn by ^ name of » plagues " and " pestilences." 1 .x word flagut is apt to con. vey, to an unprofessional person, a ve>. indefinite idea of gome great calamity, which he is unable to desci.„. but in reality> [t .g neither more nor less than a fever. All plagu^ in medical lan. guage, are understood to have been fevers; ana s ^& distin- guished one from the other, by their types, or pecu^ cnaracter of their symptoms. Thus, the Egyptian plague is a fev ^ wnich bears a strong resemblance to ordinary typhus, in produc^ extreme depression of the constitutional powers of the patit,^ and it is distinguished from typhus, by being attended with swell- ings of the glands, in different parts of the body. The plague of London, which, in 1665, destroyed, Avithin the bills of mortality, eight thousand persons in one Aveek, was similar to that of Egypt. Varieties of the same virulent epidemic, are probably pointed at in the writings of Thucydides and Galen, as having prevailed in the earlier ages, at Athens and Rome. At all events, it seems certain, that during nearly one half of the sixth century, and * SMALL POX. 499 several periods since, large portions of Europe, and of Asia, were devastated by the Egyptian scourge. Small pox is a plague Avhich, previous to the practice of vaccina- tion, exercised a still more destructive power, even than the pre- ceding disease; but it does not appear that the physicians of an- cient Greece or Rome, were at all acquainted with the small pox. For the traces of its earlier progress, we must look farther east. In the traditions of the people of China and Hindostan, small pox was enumerated as one of their common diseases; and in some of their earliest books, devoted to religion and philosophy, descriptions of it have been found to exist. China or Hindostan, then, must be considered the cradle of small pox. We have no means, however, of ascertaining in which of the two it first ap- peared, or of offering a rational conjecture, to explain the manner of its first production, beyond the fact, that these countries have, from remote ages, swarmed with inhabitants, and been subject to dreadful inroads from famine, circumstances of themselves, emi- nently favorable to the generation of pestilence. According to the Chinese and Brahminical authorities, there is written evidence to shoAV that small pox had been established in their respective countries, during a period of three thousand years and upwards. Although it had prevailed so long in China and Hin- dostan, the first notice of its appearance in Western Asia, cannot be dated earlier than the middle of the sixth century, and Fm-ope was not invaded until a later period. Tbe op-»ch to which we allude, as .the recorded commence—114 otits western ravages, was the year 569, when the city of Mecca, in Arabia, was besieged by an army of Abyssian christians, under the command of Abreha, with the expectation of being able destroy the kaaba or pagan temple, contained within that city. In this army the small pox committed dreadful havoc, and we are told that measles made its appearance there at the same time. From the siege of Mecca, A. D. 569, to the siege of Alexandria, in 639, not any of the Arabian records that have come down to us, make mention of the progress of small pox. During this interval, however, the disease was undoubtedly propagated in various directions, in the wake of the victorious Arabs, Avho were assembled and led forth to Avar, under the banner of their prophet. War has ever been the ready dis- seminator of pestilence, and as Persia and Syria were soon after- 500 MISCELLANEOUS. wards subdued by the successors of Mohammed, Ave may fairly conclude that small pox was imported, Avith its conquerors, into these countries, if it had not previously reached them. On the other hand, Amron, the lieutenant of the Caliph Omar, invaded Egypt in 638. In tAvo years he captured Alexandria. It is con- jectured that small pox was communicated by the Mohammedan troops, to the inhabitants of this city, during the siege. Ahron, an author Avho lived in Alexandria at the time, Avrote a treatise on small pox, to Avhich Rhazes, the distinguished Arabian physician, alludes. Unfortunately, Ahron's Avork has since been lost. The rapid and prolonged success, Avhich noAV attended the Saracens by land and sea, opened iu?av channels for the diffusion of small pox; and in attempting to folloAv its progress AvestAvard, along the shores of the Mediterranean, Ave have no more certain guide than the chronological details of Saracenic conquest. Okba Ebn Nafe, the general of Amron, subdued that portion of Africa lying be- tAveen Barka and Zorveliah, including Avhat now constitutes the piratical state of Tripoli. To him succeeded others, who pushed the dominion of the Saracens still further. In 712, their armies made a descent on Spain. After defeating Roderick, the last king of the Goths, they took Toledo, and eventually overrun the whole country. About the year 732 the Saracens crossed the Pyrenees. Consequently, with the period of this invasion, we may date the introduction of small pox into that kingdom. Small pox proba- bly reached Brit<^„ about the beginning of the ninth century; but no distinct notice of this dia^o, is furnished by the writers of the the time. Sunk in the ignorance of the middle ages, they alloAved the Avorst scourge that had ever thinned the human race, to pass Avithout description ; or if mentioned at all in their meagre chroni- cles, it is only under the name of "plague," or of "consuming fire;" epithets then apparently applied to eruptive pestilence in common. When small pox enters a locality Avhere it had not been before, its first effects are almost always more extensively destructive than any subsequent. Happily, in the present day, we can form, from our own experience, no conception of the mortality, that in all probability marked its early course in Eng- land. A deadly pestilence, to one attack of which, every individual, in every rank in life, the highest as well as the lowest, is liable, SMALL POX. 501 must necessarily have filled the country, from one extremity to the other, with sickness and with death. To aggravate the occur- rence of such an evil, no disease is, in itself, more loathsome than small pox. The victim of the attack, more particularly in the confluent variety, presents a most pitiable spectacle. In this form the patient is seen laboring under a fever Avith the most typhoid or putrid symptoms. He is, at the same time, completely covered from head to heel with pustules, which not unfrequently coalesce, and ultimately change the whole surface of his body into one continued sore, that renders his features undistinguishable to his dearest friends, and converts him into an object of disgust to their senses. Nor are the immediate sufferings and danger of death the only misfortunes attendant on small pox. In case the patient lin- ger through the fever, or finally survive the attack, it is often at the sacrifice of every thing considered desirable in personal ap- pearance. Beauty may be transformed into deformity ; and what is of far greater importance, by the loss of sight, the patient may be condemned to pass the remainder of his life in total darkness. Countries which have received small pox comparatively in mod- ern times, afford striking examples of the magnitude of the calami- ty in its unmitigated terrors. In 1517, St. Domingo was infected. The island then contained, it is said, a million of Indians; but this unfortunate people Avere altogether destroyed by small pox, and the murderous arms of their Spanish invaders. About 1520, small pox commenced in Cuba. From thence it Avas carried to Mexico. Within a short period, according to computations that have been made, the pestilence destroyed in the kingdom of Mexi- co alone, three millions and a half of the inhabitants. The em- peror, brother and successor to Montezuma, Avas among the vic- tims. At subsequent periods, different parts of the American continent suffered much. Whole nations of warlike Indians were almost extirpated, and piles of bones, found under the tufted trees in the interior of the country, have been supposed to bear testimo- ny to the ravages of small pox. Peculiarities of climate exercise no mollifying influence over the virulence of small pox. Iceland was invaded in the year 1707, and it suffered as much as the south em regions. The inroad destroyed sixteen thousand persons, more than a fourth of the estimated population of the island. Greenland escaped until 1733. In that year small pox appeared, 502 MISCELLANEOUS. and carried off nearly all its inhabitants. Small pox is now fami- liar to every section of the globe ; but Ave hear of it no longer as a scourge to SAveep aAvay the population of an extensive district, with a rapidity and poAver approaching to those of the tornado. The beneficent Providence, Avhich, for the fulfilment of its OAvn mysterious purposes, tolerates the groAvth and extension of nume- rous plagues, has placed Avithin the reach of human intelligence, numerous remedies, capable either of alleviating or of completely obviating their dangerous effect. Without the aid of inoculation and vaccination, it is calculated that at least one-fourteenth of every generation of mankind Avould perish beneath the deadly taint of small pox ; but that Avere inoculation generally practiced, the mor- tality would not amount to one in seventy of those on whom the operation had been performed; and under the protective influence of vaccination, that one death is not to be expected in many hun- dreds of persons so treated. Inoculation has, of late years, been wisely abandoned by the medical profession. Vaccination is re- commended in its stead. Remark.—We are assured that our remedies have proved effec- tual in a number of cases of small pox and varioloid, where these diseases appeared as an epidemic. Our correspondents assure us that they have been enabled to overcome the disease with much ease, and that no failures have occurred. It is a long time since Ave have known that our remedies Avould cure the scarlet fever, chicken pox and measles. The number of small children who have been benefitted in our own city is very considerable ; in fact, we know not of a single failure. ANATOMY. The polypus receives new life from the knife which is lifted to destroy it. The fly-spider lays an egg as large as itself. There are 4041 muscles in a caterpillar. Hook discovered 14,000 mir- rors in the eyes of a drone, and to effect the respiration of a carp, 12,000 arteries, veins, and bones, etc., are necessary. The body of every spider contains four little masses, pierced with a multitude of imperceptible holes, each one permitting the passage of a single PULSE. 503 thread; all the threads, to the amount of 1000 to each mass, are joined together when they come out, and make the single threads Avith which the spider spins its web; so that which we call a spi- der's thread consists of more than 1000 united. Lewenhock, by means of a microscope, observed spiders no bigger than a grain of sand, who spun thread so fine, that it took 4000 of them to equal in magnitude a single hair. How great must be that being, whose continual supervision up- holds in existence all the workmanship of his hands of such vast disproportions in magnitude! THE PULSE. The pulse is nothing more than the beating of an artery. Every time the heart contracts, a portion of blood is forced into the arte- ries, which dilate or swell to let it pass, and then immediately re- gain their former size, until, by a second stroke of the same organ, a fresh column of blood is pushed through them, when a similar action is repeated. This swelling and contracting of the arteries, then, constitute the pulse, and consequently it may be found in every part of the body where those vessels run near enough to the surface to be felt. Physicians look for it at the wrist, from mo- tives of convenience. The strength and velocity of the pulse vary much in different persons, even in a state of perfect health. It is much quicker in children than in adults; and in old men it grows slow and feeble, owing to the decreased energy of the heart. The pulse is in- creased both in strength and velocity by running, walking, riding and jumping; by eating, drinking, singing, speaking, and by joy, anger, etc. It is diminished in like manner by fear, want of nour- ishment, melancholy, excessive evacuations, or by whatever tends to debilitate the system. In feeling the pulse, then, of sick persons, allowance should be made for these causes; or what is better, we should wait until their temporary effects have escaped. A full, tense, and strong pulse, is when the artery swells boldly under the finger, and resists its pressure more or less; if, in addi- 504 miscellaneous. tion to this, the pulsation be very rapid, it is called quick, full, and strong; if sIoav, the contrary. A hard, corded pulse, is that in Avhich the artery feels like the string of a Adolin, or a piece of tightened cat-gut, giving consid- erable resistance to the pressure of the finger. The soft and intermitting pulses are easily knoAvn by their names. In case of extreme debility, on the approach of death, and in some particular diseases, the artery vibrates under the finger like a thread. In feeling the pulse, three or four fingers should be laid on it at once. The most convenient spot to do this, as already mentioned, is the Avrist; but it can be readily done in the temple, just before, and close to the ear, in the bend of the arm, at the under part of the lower end of the thigh, among the ham-strings, and on the top of the foot. There are two kinds of blood-vessels in the human body—arte- ries, and veins. The arteries carry the blood from the heart to the extremities of the body, Avhere they are connected Avith the veins, Avhich bring it back. An artery pulsates, or beats; a vein does not. LIFE OF MAN. The following curious observations on the duration of the life of man, as shoAvn by the bills of mortality of various countries, is translated from the French : It is surprising to compare the different ravages of death in large cities and small villages. In the Pays du Vaud, and in the village of Brandenburg, the number of deaths, in the space of one year, is, with respect to the surveyors, in proportion of four to one hun- dred and eighty ; and in the tOAvn of Shrewsbury, in England, in the proportion of four to one hundred and thirty. On the con- trary, in London, four persons die out of eighty-three ; at Vienna, three out of eighty-seven ; and, at Berlin, four out of one hundred and six. This simple comparison sufficiently demonstrates the truth of the common observation that large populous cities are the sepulchres of the human race. The most exact calculations Avhich have been made in France, LIFE OF MAN. 505 Italy, Prussia, Holland, and Sweden, clearly show that, in all ages, more deaths happen among men than among Avomen. By a list furnished by M. Susmich, at Berlin, it appears that four hundred and eighty-tAvo males died under the age of one year, and only three hundred and sixty-six females. At Berlin, also, upon a cal- culation of four years, six thousand two hundred and ten males Avere born, eight thousand seven hundred and twenty-four females, Avhich is almost twenty-one to twenty. M. Leparcieux, at Paris, and M. Wargentin, in Switzerland, plainly prove that women, in general, not only live longer than men, but that married Avomen, in particular, have a singular ad- vantage over those Avho are unmarried. This is so manifest that, in one of the cantons in Switzerland, the number of maidens doubled that of the wives. But in that state of marriage, the wives live much longer than the husbands. At Breslaw, in the course of eight years, one thou- sand eight hundred and ninety-one married men died, and only one thousand one hundred and ninety-six married women. By an exact account taken in Pomerania, it appears that, in the course of nine years, thirteen thousand, five hundred and sixty-six married men died, and only ten thousand married Avomen. In Scotland, it is calculated that, in thirty-one marriages, twenty of the men will die as soon as twelve of the women, and in that proportion; but, in a state of Avidowhood, the case is quite different; that situation is greatly in favor of the men. At Dresden, the exact register of deaths were kept for four years, which clearly proved that five hundred and eighty-four Avidows died during that period, and only one hundred and forty-nine widowers. At Wirtemburg, in the space of eleven years, three hundred and seventy-eight widows died, and but ninety widowers. At Gotha, the proportion is seven hundred and ninety widows to tAvo hundred and ten widoAvers. In Pomerania, the difference is still greater. It is beyond a doubt that large cities tend to diminish popula- tion. Man, naturally fond of society, finds his destruction in so- ciety, or rather in the abuses of society. At Paris, Vienna, Am- sterdam, Copenhagen, and Berlin, the number of births is always considerably less than that of the deaths. On the contrary, where the air is more pure, where agriculture flourishes, and simplicity of manners is adopted, population increases Avith great rapidity. 64 506 MISCELLANEOUS. Dr. Herberden informs us that, in the island of Madeira, the num- ber of inhabitants doubled in the course of eighty-four years ; and, in the American colonies, the augmentation is still more conside- able. ANTIARIS. Antiaris is the botanical name of the half-fabulous Upas Tree, of Avhich so many idle stories Avere propagated some years since by travelers. It Avas said to be a large tree growing in the island of Java, in the midst of a desert, caused by its OAvn pestiferous quali- ties ; exhalations Avere reported to be so unAvholesome that, not only did they cause death to all animals Avhich approached the tree, but even destroyed vegetation for a considerable distance round it; and, finally, the juice Avhich floAved from its stem, when Avounded, was said to be the most deadly of poisons. To approach the Upas Tree, even for the momentary purpose of Avounding its stem and carrying away the juice, Avas stated to be so dangerous, none but criminals under sentence of death could be found to undertake the task. As is usual in such cases, this fable is founded upon certain na- tural phenomena which occur in Java. There is such a tree as the Upas, and its juice, if mixed Avith the blood in the body of any animal, is speedily fatal; and there is also a tract of land in the same island on which neither animal nor plant can exist. But the two circumstances have no relation to each other. The poisoned tract is a small valley completely surrounded by a steep embank- ment, like the crater of a volcano, and is continually emitting from its surface carbonic acid gas, Avhich is alike fatal to animals and plants. On the other hand, the poisonous Upas Tree is not an inhabitant of the valley, for nothing can live there, but it flourishes in the Avoods, in the midst of other trees, Avhich are unharmed by its vicinity. In the eye of a botanist, the Upas is a species of the genus Antiaris, Avhich belongs to the natural order Artocarpeoe, a group of plants, all of Avhich abound in a milky juice, and many of which are extremely poisonous. Of the original species, Atoxi- caria, we have met with no scientific figure ; it is, hoAvever, culti- vated in the Botanical Garden at Calcutta, whence we have a leaf LIFE OF MAN. 507 or two. They are very much like those of the following plant, Amacrophylla, which has been found on the north coast of New Holland. The genus Antiaris has its stamens and pistilla in se- parate flowers. The former are collected in little heads in the center of a minute three or four leaved calyx, of which a consider- able number is enclosed in a hairy involucrum formed of several fleshy divisions which are rolled inwards. The pistillum is sur- rounded by a calyx of several leaves terminating in a long tAvo- parted style, and contains a single suspended ovulum. The pis- tilla and the antheri ferons flower-heads stand in pairs, side by side, in the axilla? of the leaves. GLOSSARY. Abdomen, the belly. Abscess, a tumor containing pus, as a boil or other swelling. Abortion, the premature expulsion of the foetus from the womb. Acid, that which imparts to the taste a sharp or sour sensation. Acrid, sharp, pungent, corrosive or heating. Acrite, sharp, ending in a sharp point; when applied to disease, means one which is attended with violent symptoms, and comes speedily to a crisis. Adipose, fat. Affusion, the act of pouring a liquid upon any other substance; as of pouring water upon a diseased body. Albumen, a constituent part of the animal solids ; it exists abun- dantly in the whites of eggs. Alkali, a substance Avhich neutralizes acid: saleratus, (a prepara- tion of pearl-ash,) is one of the principal alkalies used by the Thomsonians. Alvine, relating to the intestines, the discharges from which are termed alvine. Amenorrhea, an obstruction of the menses. Anodyne, any medicine which eases pain. Anthelmintics, medicines Avhich expel or destroy worms. Anti-bilious, that which opposes or removes the great accumula- tion of bile. Antidote, a preservation against, or a remedy for diseases, and particularly for poisons. Anti-dysenteric, that which prevents or removes the dysentery. Anti-emetic, that which opposes or removes vomiting. Anti-morbific, that which prevents or removes disease. Anti-septic, that Avhich removes or tends to prevent putrefaction. Anti-spasmodic, that which removes or tends to prevent spasms. Anti-syphilitic, that which removes or prevents venereal disease. 510 GLOSSARY. Antiphlogistic, the mode of treatment adopted by the medical fa- culty, to Aveaken the system and diminish the vital power. Bloodletting, purging and leeching are among the antiphlo- gistic remedies. Anus, the fundament. Aperients, medicines which operate gently on the bowels. Aromatic, fragrant; a plant Avhich yields a pleasant spicysmell, or a Avarm, pungent taste. Ascites, dropsy of the belly. Asphyxia, apparent death ; suspended animation. Asthenia, a term used by Dr. BroAvn to signify diminished vital energy. Astringent, that which corrects looseness and debility, by render- ing the solids denser and firmer; known by its puckering ef- fect upon the mouth. Belching, the act of ejecting Avind from the stomach by the mouth. Bile, a bitter fluid, secreted by the liver, and poured into the in- testines, to assist in the process of digestion. Bronchia, the air-tube in the lungs. Bronchocele, a disease Avhich is marked by a tumor on the fore part of the neck, and seated betAveen the trachea and skin, occupying generally the thyroid gland. Bubo, a SAvelling on the groin. Caloric, heat. Calculi, small concretions, or stones Avhich are found in the kid- neys. Canker, a false membrane or pseudo membranous lining of the stomach and boAvels ; in chronic cases, it is hard and tough, and of a grayish color. Capillary vessels, the small ramifications of the arteries and veins. Carbon, a name applied by chimists to charcoal. Carbonic acid gas, fixed air ; a compound of carbon and oxygen. It may be found by burning charcoal ; it is emitted also by bodies in a state of vinous fermentation ; it is often found, also, in a state of nature, at the bottom of wells, caverns, etc.; hence the sudden death, sometimes, occasioned by a descent into those places. Cartilage, an elastic substance, usually termed gristle, Avhich con- nects the bones, and assists their movements upon each other. Carminative, a medicine which expels wind. Cathartic, that Avhich causes purging of the intestines. Catheter, a hollow tube for draAving off the urine. Caustic, a burning application. Cellular, a little cavity or cell. GLOSSARY. 511 Cerebral, relating to the brain. Chancre, a venereal ulcer,. or sore, caused by the direct applica- tion of the virus. Choleric, easily irritated. Chronic, a term applied to diseases of long-standing ; the opposite of acute. Chyme, the food in a state of digestion, which passes from the stomach into the intestines, and mixes Avith the bile. Chyle, the milk-like fluids in the lacteal vessels. Clinical, pertaining to the bed-side lectures or observations at the bed-side of the patient. Clonic, to move to and fro. Clyster, injection. Colliquative, any excessive discharge from the body, as colliqua- tive stools, colliquative SAveats. Coma, stupor, drowsiness. Concrete, a uniform mass or layer. Congestion, undue accumulation of blood. Conjunctiva, a membrane of the eye. Constipation, costiveness. Constriction, a drawing together, or contraction, as from cold. Contagious, catching; that which may be communicated from one person to another, by contact, or by a subtile excreted matter. Convulsions, involuntary contractions of the muscles. Costive, bound in the body ; restringent. Costiveness, the state of the body in which excretion is obstructed. Cuticle, a thin Avhite membrane ; the outer skin. Decumbent, declined or bending doAvn. Delirium, an alienation of mind, or wandering of the senses, caused by the violence of fever. Diagnosis, the signs by Avhich a disease is knoAvn. Diaphoretic, that Avhich from being taken, internally, promotes perspiration, or discharges by the skin. Diaphragm, a muscle, or partition between the chest and abdo- men. Diarrhea, a purging; a looseness of the belly. Diuretics, medicines which increase the flow of urine. Digest, to dissolve ; the action of a solvent on any substance. Drastic, violent, powerful. Dropsy, a collection of serous fluid in the cellular membrane in the vicera and the circumscribed cavities of the body. Duodenum, the first portion of the small intestines. Dysentery, a purging attended Avith bloody stools. Dyspnoea, difficulty of respiration; oppressed breathing. 512 GLOSSARY. Dyspepsia, a difficulty of digestion. Dysuria, difficulty and pain in passing urine. Endemic, a term applied to diseases which are especially prevalent in certain localities or districts. Effluvia, exhalations from diseased bodies or other substances, Avhether noxious or otherAvise. Ejection, discharges from the stomach by vomiting. Emetic, a medicine which provokes vomiting. Enema, a clyster or injection. Engorgement, a stagnation of fluids in a part. Epidemic, a contagion, or other disease, that attacks many people at the same season, and in the same place. Epidermis, the outer skin, called the scarf skin. Epigastric region, the portion of the abdomen immediately over the stomach. Epispastics, substances Avhich blister the skin, as Spanish flies. Eruptive, the bursting forth of humors on the surface of the skin, in the form of pustules, etc. Erratic, Avandering, irregular. Erysipelas, St. Anthony's fire. Etiology, relating to the cause and origin of diseases. Exacerbation, an increase of fever. Excretive, having the power of separating and ejecting fluid mat- ter from the body. Excrement, the alvine discharges or stools. Excretions, useless substances Avhich are discharged from the body, as urine and perspirable matter. Excitability, that condition of the body Avhich renders it suscep- tible of stimulant impressions. Exfoliate, to scale off, as a piece of dead bone. Exhalents, small vessels or pores Avhich convey the perspirable matter out of the system. Exhibition, the administration of medicine. Exotic, foreign; not a native. Expectorant, medicines Avhich increase the discharge of mucui from the lungs. Febrile, pertaining to, or indicating fevers. Flaccid, soft; yielding. Flatulency, Avindiness in the stomach and intestines. Flour Albus, Avhites or Leucorrhea. Fomentation, a sort of partial bathing, by applying flannels dipped in hot Avater, or medical decoctions, to any part, Formula, a physician's prescription; a Avritten or specified form. Function, the action or office performed by any organ, as the func- tions of the heart; the functions of the liver. GLOSSARY. 513 Fundament, see anus. Fur, a coat of morbid matter collected on the tongue of a diseased person, especially in fevers. Fceces, the stools, or alvine discharges. Gas, a permanently elastic uniform fluid. Gastric, appertaining to the stomach. Gangrene, mortification. Gargle, a medicated preparation for Avashing the mouth and throat. Gestation, the period of pregnancy. Gland, a part of the body destined for the secretion of some par- ticular fluid. The salival glands secrete the saliva; the liver, which is also a gland, secretes the bile. Granulation, the act of forming into small grains. Gravid, pregnant. Gonorrhoea, a puriform discharge from the urethra with Or without dysuria, lascivious inclination, and not following an impure connection, in many instances. Hectic, habitual; denoting a slow, continual fever, marked by pre- ternatural, though remitting heat, which accompanies the con- sumption, etc. Hemiphlegy, a palsy that affects one half or side of the body. Hemorrhage, fluxes of blood, proceeding from the rupture of a blood-vessel, or some other cause. Hemorrhoidal, pertaining to the vessels which are the seat of the hemorrhoids or piles. Hernia, a rupture. Herpetic, having the character of a tetter. Hydrocele, a disease of the testicles. Hydrocephalus, dropsy in the head. Hydrogen, an aeriform fluid gas, of the lightest body known, and is used for inflating balloons. It forms one of the elements of water, being about fifteen parts to one hundred of that li- quid ; and is fatal to animal life. Haemoptysis, bleeding from the lungs. Hypochondriasis, the vapors; spleen; a disease which is attended by languor or debility, lowness of spirits or melancholy; the sufferer often apprehending great evil to himself. Hysterics, a disease of women, characterised by spasmodic affec- tions of the nervous system, and often attended by hypochon- driacal symptoms. latroleptic, the method of curing disease by unction and fric- tion—the administration of medicine by cutaneous absorp- tion. Icterus, jaundice. 65 514 GLOSSARY. Idiopathic. a term used to designate a disease Avhich exists inde- pendent of any other; opposed to symptomatic disease, Avhich is dependent on another. Ichorous, a thin aqueous and acrid discharge. Infectious, that Avhich taints or corrupts; having qualities which may communicate disease from one to another. Infusion, the liquid procured by steeping any substance in cold Avater. Inguinal, relating to the groin. Inoculation, the insertion of poison into any part of the body. Inspiration, the act of draAving air into the lungs. Intermittent, a disease Avhich ceases for a time and then returns, as agues, etc. Irritability, the capacity of being moved or excited into action. Lacteals, vessels Avhich arise from the intestinal coats of the small intestines and absorb the chyle, Avhich is conveyed to the throracic duct and finally converted into blood. Lamine, a scale or plate. If is used for the foliated structure of bones or other organs. Laxative, a medicine that relaxes the bowels; a gentle purgative. Lethargy, a morbid droAvnsiness or sleepiness; a continued or profound sleep, from which a person can scarcely be awaken- ed, and if Avaked, remaids stupid. Leucorrhea, the Avhites, generally termed fluor albus. Ligament, a strong, elastic membrane, by which the joints are connected together. Lithotomy, a surgical operation, for the removal of stone in the bladder. Local, confined to a particular part. Loins, the small of the back. Lumbago, rheumatism in the loins. Lumbar region, a term applied to the loins. Lymph, a colorless fluid, separated from the blood, and contained in small vessels called lymphatics. Mania, delirium; madness. Malaria, poisonous exhalations from marshes and putrifying sub- stances. Materia Medica, that branch of medical science which treats of the nature and properties of substances employed for the cure of diseases. Matrix, the womb. Membrane, a thin flexible skin, serving to cover some part of the body. Metastasis, the translation of disease from one part to another. GLOSSARY. 515 Menstrum, the name given to any liquid, into which a substance is put to extract its virtues; Avater, for instance, is the men- strum ot all salts, vegetable gums, and animal jellies; recti- ned spirits of Avine is the menstrum of essential oils and vegetable resins. Miasm, synonymous with malaria. Molar Teeth, the double or grinding teeth. Morbid, diseased. Morbific, relating to disease. Mucilage, a fluid of a thick, shiny, ropy and soft consistence. Mucus, a transparent, saline, glutinous fluid. Muscles, portions of the flesh, susceptible of contraction and re- laxation. Narcotic, a medicine which has the power of procuring sleep by stupefaction. Nausea, an inclination to vomit, without effecting it; also a dis- gust of food, approaching to vomiting. Nephretic, affections of the kidneys. Nerves, long Avhite cords, which have their origin in the brain and spinal marroAv, and are distributed to every part of the body. It is the nerves Avhich render us sensible of pain. Nervine, anything that affords relief from disorders of the nerves. Neuralgia, pain of the nerves. Nucleus, anything about which matter is collected. Nitrogen, an elementary, gaseous fluid, incapable of supporting animal life; composing about four-fifths of the atmospheric air. Nosology, a systematic arrangement of diseases into classes, or- ders, genera, and species. Obtuse, when applied to pain, means dull, not sharp or acute. QZdma, a SAvelling from a dropsical collection between the skin and muscles. Olfactory, relating to the sense of smelling. Ophthalmia, inflammation of the eyes. Organic Affection, a disease in Avhich the structure of a part is deranged. Organ, a part which has a determined office in the animal econo- my. Ossified, changed into bone. Oxygen, the great supporter of animal life. It forms about one- fifth of the atmospheric air, and is a constituent part of all bodies in the animal and vegetable kingdoms. Without oxy- gen we could not breathe, nor Avithout it could there be any combustion. 516 GLOSSARY. Pancreas, a soft, suple gland, situated in the loAver part of the abdomen, which secretes a kind of saliva, and pours it in the duodenum. Palpitation, a fluttering or convulshre motion. Paralysis, a palsy. Parotid, the name of certain glands, beloAV and above the ear. Paroxysm, 1st, an obtuse increase of the symptoms of a disease, Avhich lasts a certain time, and then declines; 2d, a periodical attack or fit of a disease. Pathognomonic, a term given to those symptoms Avhich are pe- culiar to disease, and Avithout which the disease does not exist. Pathology, the doctrine of diseases. Pectoral, pertaining to the breast. Peripneumony, inflammation of the lungs. Peristaltic, the worm-like motion by Avhich the intestines push forward their contents. Perspiration, evacuation of the fluids of the body through the pores of the skin; the matter perspired, or sweat. Petechia, a red, purple spot. Phlegm, a thick, tenacious mucus, secreted in the lungs. Phlemasia Dolens, the big leg which sometimes happens to lying- in Avomen. Plethoric, fullness of blood. Pleura, a membrane Avhich lines the internal surface of the thorax or chest. Inflammation of this membrane is termed pleurisy. Pleuritic, of the character of pleurisy, attended Avith pain in the side of the chest. Polypus, a tumor Avhich is generally narroAver where it originates, and then becomes wider somewhat like a pear. Predisposition, that state of the body Avhich renders it susceptible of any particular disease. Primae Viae, a term applied to the stomach and intestinal tube. Prolapsus, a falling out, or falling down, of some part of the body. Prolific, fruitful. Proximate, nearest; next; a proximate cause is that Avhich im- mediately precedes and produces any particular effect. Pulmonary, relating to the lungs. Pungent, sharp; biting; prickling; stimulating. Purges, > medicines which increase the intestinal discharges Purgatives, § by stool. Purulent, having the appearance or qualities of pus. Pus, matter; a whitish, cream-like fluid, found in inflamed ab- scesses, or on the surface of sores. Pustules, small pimples, or eruptions on the skin, containing pus. GLOSSARY. 517 Putrescent, becoming putrid; tending to putrefaction. Pyrexia, fever. Pyrosis, Avater-brash; heart-burn. Quartan, an ague which returns every fourth day. Quotidian, an ague which returns daily. Radical, pertaining to the root. Rectum, the last portion of the intestines, terminating in the anus. Refrigerating, cooling; allaying heat of the body or blood. Region, a term applied to the respective divisions of the body. Remittent, to abate in violence for a time, without intermission. Resolution, the dispersing of a tumor, or inflammation, without suppuration. Respiration, act of breathing. Retching, straining to vomit. Rigidity, stiffness; want of pliability; the .quality of not being easily bent. Rigor, a sense of chilliness, with shivering and contraction of the skin. Rubefacient, a substance which, when applied a certain time to the skin, induces a redness without blistering. Saliva, spittle. Salivation, an inordinate flow of the saliva, accompanied with irritation of the mouth and gums. ■ Sanguine, abounding with blood; plethoric. Sanguineous, relating to the blood. Scirrhus, a hardening of a gland, which generally terminates in cancer. Scrotum, the skin which covers the testicles. Secretion, that which is derived or separated from the blood. The tears, saliva, bile, etc., are termed secretions. Sedative, that which diminishes the vital energy. Sedentary, accustomed to sit much. Sensorium, the brain, the center of feeling. Septic, relating to putrefaction. Serum, the Avatery portion of the blood. Skeleton, the articulated dry bones of an animal. Slough, a separation of the dead from the living flesh. Spasms, cramp; convulsions. Spasmodic, pertaining to cramp or convulsions. Sphacelus, gangrene; mortification. Spinal, relating to the back-bone. Spleen, the milt. A spongy viscus, placed on the left side, be- tween the eleventh and twelfth false ribs. Stomachus, the stomach. 51S GLOSSARY. Stimulants, medicines Avhich excite the system into increased ac- tion. Stool, an evacuation from the boAvels. Strangury a difficulty of voiding urine, attended Avith pain. Sterility, barrenness. Strumous, scrofulous. Styptic, that Avhich stops the discharges of blood. Subsultus, weak convulsive motions of the tendons. Sudorific, that Avhich produces perspiration; synonymous Avith diaphoretic. Suppuration, the formation of pus, or matter, in inflammations, tumors, etc. Sutures, the seams which unite the bones of the skull. Symptomatic the consequence of some other affection. Syncope, fainting or SAvooning. Synocha, inflammatory fever. Syphilis, the venereal. Tenesmus, a continual and urgent desire to go to stool, Avithout a discharge. Tenia capitis, scald-head. rr, .' £ stretched; strained to stiffness; rigid. Tension, 5 Ll&lu- Tepid, moderately Avarm. Tertian, a disease Avhose paroxysms return every other day. Tetanus, the locked jaAv. ' Therapeutic, relating to the employment of .-remedies. Tlwrax, the chest. Titillation, tickling. Tonic, a medicine that increases the strength or tone of the ani- mal system. Tonsils, an oblong gland in the fauces. Topical, confined to a particular part. Tormina, griping pain. Transpiration, the passage of useless matter from the body, either through the pores of the skin, or from the lungs. Hence we say cutaneous transpiration, and pulmonary transpiration. Tremor, an involuntary trembling. Tubercles, small hard tumors, generally found in the lungs. Tumefy, to SAvell. Tumor, a morbid SAvelling or enlargement of a particular part. Turbid, muddy, cloudy, dirty. Typhoid, resembling typhus; weak, low. Ulcer, a sore which discharges pus, or matter. Ulceration, the process of forming into an ulcer. GLOSSARY. 519 Urethra, the membranous canal by which the urine is conducted from the bladder and discharged. Ureters, the tubes which'convey the urine from the kidneys to the bladder. Uterine, appertaining to the uterus. Uterus, the womb. Uvula, a small conical fleshy substance hanging near the root of the tongue, commonly called the palate. Vaccination, the act of inoculating persons with the cow-pox. Vagina, the canal which leads to the womb. Veins, vessels which convey the blood to the heart. Venous, pertaining to the veins. Ventricles, the two cavities in the heart which propel the blood into the arteries. Vermifuge, a substance that destroys or expels worms from ani- mal bodies. Vertigo, dizziness; giddiness of the head. Vesication, blistering. Viscera, plural of viscus. Viscid, glutinous; sticky. Viscus, a name applied to the organs contained in the thorax or abdomen, as the lungs, liver, etc. Volatile, capable of wasting away suddenly from exposure to the air. Error in Pagination: P. 521-528 omitted in numbering INDEX. PART I. Ague, - - - 120 treatment of, - - 121 Angina Pectoris, - - 245 treatment of, - - 247 Apoplectic Fits, - - 285 treatment of, - - 285 Asthma, - - " -212 treatment of, - - 213 Atrophy, ... 251 treatment of, - - 252 Blood, spitting of, - - 181 treatment of, - 183 voiding of by urine, - 184 treatment of, - 185 Bronchocele, - - 265 treatment of, - - 267 Calculus, ... 175 Cancer Preparations, - 45 Catarrh, - - - 191 treatment of, - - 192 Cerate, Vegetable, - - 35 Chilblains, - - - 205 treatment of, - - 206 Cholera, 83 incipient stage of, - 93 treatment of, - 105 febrile stage of, 95 treatment of, - 109 cold, or choleric stage of, 94 treatment of, - 106 treatment with our remedies, 111 appearances after dissection, 99 diagnosis of, - - 98 nature of, - - 101 prognosis of, - - 97 proportionate mortality of, 104 proximate cause of, - 111 67 Cholera Morbus, - - 167 treatment of, - - 168 Colic, - - - 169 treatment of, - - 170 Congestion, - 257 treatment of, - - 258 Consumption, Pulmonary, - 123 treatment of, - - 128 Cough, - - - 131 treatment of, - - 134 Cough, Hooping, - - 193 treatment of, - - 194 Cretinism, ... 265 treatment of, - . - 267 Croup, - - - 200 treatment of, - - 202 Derangement, Mental, - 151 treatment of, - - 156 Diabetes, - - 255 treatment of, - 256 Diarrhea, ... 165 treatment of, - - 166 Drops, Alterative, - - 42 Diaphoretic, - - 40 Female, - - 41 Dropsy, - - - 239 treatment of, - - 242 Dysentery, ... 171 treatment of, - - 172 Dyspepsia, - 139 Lotion for, 44 treatment of, - - 150 Enteritis, ... 203 treatment of, - - 204 Epileptic Fits, - - 286 treatment of, - - 286 530 INDEX. Erysipelas, - . 204 treatment of, - 205 Fever, in general, . 47 treatment of, . 57 Scarlet, - . 83 treatment Df, 83 Spotted, - 72 treatment >f, 78 Yellow, - 60 treatment Df" 65 treatm't by our remedies, 69 Fits, Apoplectic, - 285 treatment of, - 285 Epileptic, - 286 treatment Of, 286 Hysteric, 286 treatment of-; 287 Gravel and Stone, . 177 treatment of, - 178 Head-ache, Sick, . 214 treatment of, . 214 Health Restorative 39 Hematuria, - . 184 treatment of, . 185 Hemoptysis, - . 181 treatment of, . 183 Hemorrhage, . 183 treatment of, . 184 Hemorrhoids, . 186 treatment of, . 187 Hernia, . 236 treatment of, . 237 Herpes, . 226 treatment of, . 228 Hydrocephalus, . 272 treatment of, . 275 Hydrophobia, . 277 treatment of, . 281 Hypochondriasis, . 157 treatment of, . 159 Hysterics, . 160 treatment of, . 161 Hysteric Fits, . 286 treatment of, . 287 Hysteritis, . 206 treatment of, - 208 Icterus, . 259 treatment of, . 260 India, Cholera in, . 85 Influenza, . 284 treatment of, - 284 Jaundice, . 259 treatment of, - 260 Kings Evil, - - - 217 treatment of, - - 219 Leprosy, . . 253 treatment of, . - 254 Leucorrhea, - . - 209 treatment of, . . 210 Life, Essence of, . . 12 Lithiasis, . . 177 Liniment, for Cholera Morbus, 27 Coughs and Consumption, 29 Fevers, and Fever and Ague , 23 Head-ache, . . 33 Laxative, . . 34 Nervous Affections, . 25 Rheumatism, . . 31 Stimulating, - - 19 Measles, . . 194 treatment of, . . 197 Menstruation, Obstructed, . 248 treatment of, . . 248 Mental Derangement, . 151 treatment of, . . 156 Milk-sickness, . . 282 treatment of, . . 283 Mind, Depressed state of, - 162 treatment of, . . 163 Morbus, Cholera, - . 167 treatment of, - •- 168 Mortification, . . 249 treatment of, - . 251 Mumps, - . 198 treatment of, - - 200 Neck, Swelled, . 265 treatment of, . . 267 Nervous Diseases, . . 261 treatment of, - - 262 Ointment, Itch, . 38 Venereal, - - 36 Parotitis, . _ 198 treatment of, . . 200 Pectoris, Angina, - . 245 treatment of, . . 247 Phlegmasia Dolens - . 267 treatment of, . 271 Phthisis, - . 123 treatment of, . _ 128 Piles, - . 186 treatment of, . . 187 Plague, - . 113 treatment of, . . 117 Polypus, - . 238 treatment of, . . 238 Prolapsus Uteri, - . 211 treatment of, - - 212 INDEX. 531 Quinsy, treatment of, Rheumatism, treatment >eola, treatment of, treatment of, Rubeola, Salve, Pile, - Tetter, - Sanative, Nerve, Scald-head, - treatment of, Scrofula, treatment of, Scurvy, treatment of, Stomach, Sick, treatment of, Stone, Sunderland, Cholera in, Swelled Leg, treatment of, 189 191 134 136 194 197 35 36 43 228 229 217 219 221 222 282 283 175 92 267 271 Swelling, White, - - 231 treatment of, - - 233 syphilis, ... 223 treatment of, - . 225 Syrup, Vegetable, - - 39 Tetter, - . _ . qoc treatment of, - . 228 Tic Douloureux, - . 262 treatment of, - - 263 Tincture, Pectoral, - - 41 Tinea Capitis, - . 228 treatment of, - - 229 Uteri, Prolapsus, - - 211 treatment of, - - 212 Wash, Brown, - - 44 White Swelling, - - 231 treatment of, - - 233 Whitloe, - - 235 treatment of, - - 235 Womb, Inflammation of, - 206 treatment of, - - 208 PART II Abdomen, Distention of, Ague Cake, case of, - Ague, Quotidian, Tertian, Albus, Fluor, Ancle, Ring-bone in, Asthma, cases of, 328, 370, 319, 299, Back, Pains in, Blood, Spitting of, - Bowel Complaint, cases of, 306, 342' Bowels, Constipation of, Bladder, Inflammation of, Breast, female, Risings on the, Bronchocele, - 323, 323, Bruises, cases of, 296, 306, 331, Burns an.d Scalds, - 296, Bones, Pains in, 354 313 371 371 368 316 347 305 346 340 346 342 355 297 349 342 306 304 Canker Sores, case of, - 297 Cartilage, of the hand. Injury of, 363 Cases, Interesting, ' 317, 363, 367 Child, Remarkable case and cure of, 308 Chills and Fever, 300, 306, 323, 335 Cholera, - 296, 307, 330, 339 Cholera Infantum, - 326, 336 Cholera Morbus, 302, 306, 320 Cholera Morbus and Fever, severe case of, - 320 Colic, Bilious, 306, 330, 336, 350 Chronic Diseases, 324, 343, 361, 336 Consumption, cases of, 333, 346, 357 " " 358, 365, 367, 368 Copper-head, Bite of, - 329 Cough, Hooping, 296, 340, 355, 376 Cough, 296, 300, 319, 322, 347 of 13 years' standing, cured, 313 Croup, cases of, - 322, 349 Debility, General, - - 322 Delirium, - - 297, 310 Derangement, Mental, 291, 322, 335 " " 351 Diarrhea and Fever, 297, 302, 358 " " 376, 377 Dropsy, - - 2!J7. 323 Drowning, case of Suspended Animation by, - 329 Dysentery, - - 318, 333 Dyspepsia, 296, 297, 298, 300, 318 " 324, 325, 328, 329, 369 and Head-ache, - 301 with Despondency of mind, 292 " " 297 Disease, Complicated, case of, 301 of every type—See Doctor Turner's letter, - 367 Doctor J. Biles' letter, 371 Ear and Head, Darting pains in, 298 532 INDEX. Erysipelas, - Erysipelas and Tumors, Eyes, Sore, case of, Emaciation, case of, - 363, 365 318 312 355 Febrile Diseases, 345, 348, 351 Fever, cases of, 308,310,312,324 „ ' 55 331, 338, 343, 347 „ » 351, 355, 377 Fever, Bilious, cases of, 293, 297 ,, 5? 3U5, oil), oza Congestive, 326, 340, 354, 367 Inflammatory, - 320, 358 Intermittent, 304, 324, 331, 338 Puerperal, - - 341 Putrid, - - - 297 Scarlet, 305, 315, 330, 364 Typhus, 297, 315, 329, 373, 379 Fever and Ague, 302, 303, 348 Fever and Chills, 300, 306, 323, 335 Fever and Diarrhea, - 302 Fever and Sick Head-ache, 308 Fever and Extreme Debility, 302 Fits, cases of, 322,323,331,341 ,, ?5 - 352, 368 Fits, Convulsive, - - - 352 Fits occasioned by Croup, - 322 Freezing, case of, - - 315 Hand, Severe contusion of, - 370 Head-ache, cases of, 305, 315, 326 » 329, 331, 346, 357, 364, 371 Head-ache, Nervous, 301, 306, 321 55 " 371 Sick, 291, 308, 315, 364, 366 n - - 368 with Foul Stomach, 298 of long standing, - 291 Head, Darting pains in, - 298 Sore in, - 292 Heart and Breast, Affections of, 336 „ » " 366 Heart, Malformation of, Palpitation of, Dropsy of, Heel, its Cartilage injured, Hemorrhage, from the Lungs, - Hydrocephalus, case of, 339 303, 327 374 314 338 331 321 Insanity, cases of, 378, 379, 380, 381 Jaw, Swelling of the, Joint, Dislocated, Kidneys, Affection of, Limbs, "Weakness in, Perished, 330, 352 313 353 313 313 Liver Complaint, 323, 326, 327, 328 \> ''348, 351, 354, 355, 369 Liver, Inflammation of, - 357 Liver and Spleen, Affection of, 2.U ,, " 323, 351, 357 Lungs, Hemorrhage from the, 331 Inflammation of the, 333, 337 Measles, - - 304,305, 315 Menstruation, Suppressed, 326, 335 Deranged, - - 328, 335 Mental Derangement, 322, 335, 351 Milk-sickness, - 356 Nervous Affections, 299,314,337 Pains, in the Breast, 296, 328, 5 5 >' General, - in the Side, and Ague-cake, 55 » » and Rheumatism, attended with Fever, Deli- rium, Cough, etc., in the Head and Back, - Palpitation of the Heart, 303, Palsy, Numb, - - - Paralysis, - 307, 362, 372, Pericardium, Dropsy of the, Phthisis, - - - - Piles, cases of, 290, 303, 306, 5' " 330, 331, 342, 344, Plague, Cold, - 290, 317, Pleurisy, 303, 315, 343, 344, » _ 348, Pulmonary Complaint, Prolapsus Uteri, - 328, 338 Quinsy, - Rheum, Salt, - - - 303 Rheumatism, cases of, 292, 301, JUb » 319, 321, 323, 329, 334, 341 » 343, 345, 352, 355, 358, 360 55 - 362, 375 Inflammatory, 292, 299, 334 55 . "360, 361 Ring-bone on the Ankle, - 316 Salt Rheum, - - - 303 Scalds, cases of, 296, 306, 312, 315 Scald-head, - 290, 364, 366 Sciatica, cases of, - 316,330 Scrofula, - - - 351, 272 several severe cases cured, 317 55 55 332, 333, 363 Sick Head-ache, 291, 308, 364, 368 Side, Affection of the, - 307 1 Small Pox, - - - 315 329 341 303 313 319 300 291 303 327 337 375 374 324 307 347 318 347 351 324 373 322 INDEX. 533 Spasms, - 331 Spine, Incurvation of, - 336 Spleen and Liver, Affection of, 299 Spleen, Distention of, 357, 370 Stomach, Foul, - -. 298 Sickness at the, - 305, 341 Pains in the, - - 298 St. Vitus' Dance, - 338, 373 Swelling of the Jaw, - 330, 352 Swelling, White, - 293, 306 Glandular, - - 300 Sciatic Affections, - - 290 Sprains, cases of, - 302, 306, 331 Tetters, - - - 366 Tic Douloureux, - 355, 369 Tremor and Weakness, - 311 Tumors and Erysipelas, 318, 349 Tumefaction, 323, 349 Urine, Suppression of, - 298 Bloody, - - - 354 Urinary Canal, Inflammation of, 327 " » " 354 Urethra, . . - 355 Uteri, Prolapsus, - 328, 338, 373 Affections of the, - 291 Vertigo, 327 V» eaknessin the Limbs, caseof, 313 Weakness and Tremor, - 311 White Swelling, - 293, 306 Wounds, - - - 321 Weakness in the Back, - 290 PART III. Bile, --- - Blood, Bone, - Brain, - Breath, - Cartilage, - Chyme, - Diaphragm, - Ear, - - - - Embryo, - Eye, Human, Appendages of, Head, - Heart, Intestine, - 399 394 429 420 428 422 396 410 403 434 432 Skeleton, Human, Mechanism of, 383 Spine, ... 416 Spleen, - - - 429 423 Joint, 424 415 Kidney, 401 399 Liver, Lungs, 414 421 Muscle, 431 Nerves, 405 Ovary, 434 407 Pelvis, Uterus, 432 PART IV Acids, - Alkalies, - Aliment, - Albumen, Anatomy, - - - Animal Heat, Origin and Regu- lation of, Antidotes, - Antiaris, - Bath, Saline, Bed for Invalids, Hydrostatic, 445 Benzoin, 446 463 Caustics, 447 Potassa, 502 Chimistry, - Chimical Decomposition, 453 Clinical Medicine, - 487 Contagion, - 506 Crisis, 494 Decomposition, Chimical, 456 Diet, 448 449 449 435 451 482 485 473 451 466 534 INDEX. Digestion, - 466 Disease, Hereditary, - 496 Essential Oils, - - 450 Galvanism—Application of, to poisoned Wounds, - 495 Granulation, - - 496 Hereditary Disease, - - ^96 Hydrostatic Bed, - - 456 Hunger, ... 461 Heat, Animal, Origin and Regu- lation of, - - 453 History of Small Pox, - 498 Injections, , - - 475 Irritability, - 479 Life of Man, - - 504 Medicine, Clinical, - - 482 Nutrition, Animal and Vegetable, 493 Oils, Essential, - - 450 Perspiration, - - 470 Poisoned Wounds, Application of Galvanism to, - 495 Potassa, Caustic, - - 449 Pregnancy, ... 476 Pulse, - - - 503 Respiration, - 469 Saline Bath, - 494 Secretion, - 472 Small Pox, History of, - 498 Somnambulism, - - 474 Sympathy, - 472