[Reprinted from The Medical News, June 22, 1895.] A CASE OF HEM AT IDR OS/S COMBINED WITH CHROMIDROSIS. By ISADORE DYER, M.D DERMATOLOGIST TO CHARITY HOSPITAL ' PROFESSOR OF DERMATOLOGY, NEW ORLEANS POLYCLINIC LECTURER AND CLINICAL INSTRUC- TOR IN DERMATOLOGY, TULANE UNIVERSITY, ETC., NEW ORLEANS, LA. The case herewith reported is interesting on account of the recurrent attacks of the disease and for the variety of the location of the separate eruptions. The patient was a professional rubber in a local Turk- ish bath. He is twenty-six years old, an American, five feet eleven inches in height, and weighs 147.5 pounds. The patient called after his first eruption, but there was no evidence of the condition, and his healthy appear- ance and otherwise normal state made me somewhat skeptical of his statement. Two of the attendants em- ployed at the same bath, however, fully confirmed his description of his first attack, and the details were in- teresting. Just after rubbing a patron of the bath one of the other attendants remarked that the patient was " sweating blood " between his shoulders, and wiped off the sweat with a towel. The towel was stained with the secretion. The sweating persisted for fully half an hour, leaving the skin reddened for quite an hour after that. The patient was advised to send for me as soon as another attack occurred, and also to note any untoward experience or sensation on his own part. Meantime it was ascertained that the father was subject to similar attacks in his youth. Neither father nor son, however,. 2 was a hemophile. The man himself was normal in every way. Although of a slender frame he was well made physically, and, on examination of his chest and heart, I found him perfectly normal. The urine showed no unusual evidence. Fully two weeks after the first attack I was called to the Turkish bath to see the patient in an acute attack. He had been exposed in the hot room of the bath, but had done no rubbing. He was in no way distressed, except by his desire to hold the eruption for me to see. There was a marked scarlet eruption, involving the knee and the upper third of the right leg, arranged in a triangular manner with the base of the figure at the knee. The eruption was almost dense in its character, but here and there it was mottled. The appearance presented was that of an abraded skin, which on closer examination appeared to be, what it most likely was, a diffuse hemorrhage into the skin. There were absolutely no subjective symp- toms, and there were no signs of swelling or of inflamma- tion, simply the startling scarlet redness of the eruption. A sketch was rapidly made of the patch, which faded while this was being done. There had been no sweat- ing with this eruption, but the patient assured me that the former attacks had been preceded and followed by just such an eruption. At the time I was called the eruption had been present for an hour. It was fully an hour under observation, and the patient assured me sub- sequently that it lasted fully an hour after his leaving me. In fading, the patches became broken, fading first in the center, until finally only the margins were apparent. Between the first attack and the one here described the patient informed me that he had had one on the chest. Just nine days subsequent to the attack described the patient reported, with a two-ounce bottle filled with a fluid the color of ordinary carmine ink. This he stated had been collected from his back during an attack the night before, which had lasted longer than any of the 3 preceding attacks, and which, for the first time, had left him weak and with pains in the joints. The fluid was examined by Dr. Pothier, the pathologist of Charity Hospital, and found to contain a mass of broken-down epithelial cells and fibers of cotton, stained red. There were no blood-corpuscles. Acids produced no reaction, and alkalies rendered the liquid colorless. Chemic agents, iron, etc., gave no reaction for blood. The staining of the fibers and the absence of blood-cor- puscles or coloring-matter of the blood argued for a true chromidrosis. There was no suspicion of fraud on the part of the patient, and no occasion for it. Be- sides, the testimony of three other individuals who had witnessed the previous three attacks, and of one of these who twice had wiped off the sweat and had finally col- lected the fluid, must be considered reliable. Moreover, the patient did not wear colored underwear, but gray worsted and flannel mixed. The patient had been an attendant in the same bath for nearly a year, and seemed to have been affected in no other way by this new occu- pation. He had taken no drugs for an indefinitely long period preceding the eruptions. The change of occu- pation and the physical exertion incident to the rubbing at the bath seem alone to determine the cause of the eruption. The hereditary tendency might be remarked, but, of course, is to be qualified accordingly. The case is of some clinical interest from the sex and age of the patient, and from the concurrence of the two generally accepted reflex disturbances of the sweat-glands. Under my advice the patient left the Turkish bath, and since changing his occupation to one of out-door life he has had no recurrence of the affection, although over two months have elapsed. 124 Baronne Street.