Extracted from the TRANSACTIONS OF THE COLLEGE OF PHYSICIANS OF PHILADELPHIA, THIRD SERIES, VOLUME VI. A NOTE ON TIIE FECES OF ST ARCH-FED INFANTS. Br / N. A. RANDOLPH, M.D. ASSISTANT DEMONSTRATOR OF PHYSIOLOGY IN THE UNIVERSITY OF PENNSYLVANIA. [Read June C, 1883.] The scries of experiments presented in the preced- ing paper by Dr. Keating seems to me to be in the highest degree suggestive, for it is byily rational to suppose that the development of the hmylolytic fer- ment of the pancreatic juice is coincident with the appearance of the analogous salivary ferment.1 Inas- much, however, as the food even in spoon-fed infants is retained but a short time in the mouth, and further, as the continued action of the saliva after it enters the stomach is as yet problematical, the only absolute control for such observations is afforded by an exami- nation of the feces. Through the kindness of Dr. Iveating I have been enabled to examine the stools of twenty-four starch- fed infants, of ages varying from forty-five days to eighteen months. Twenty-three of these children were fed upon cracker-dust, water, and condensed 1 [The observations in question demonstrated the functional activity of the saliva of very young infants.] ,, , ---- 444 RANDOLPH, milk. The twenty-fourth received corn-starch boiled in milk. The freshly evacuated feces of each infant were carefully bottled and labelled, and a drop of a solution of iodine was added to a small portion of each speci- men, which was then submitted to microscopical examination. Besides turning the starch blue, and indicating the presence of dextrine by a peculiar ma- hogany-red color, the iodine has the advantage of rendering any fats which may be present much more readily apparent. The reaction of each specimen was taken, but though this varied from acid to alkaline and neutral, no correlation between the reactions and the other properties of the specimens could be ob- served. A decoction of each was tested for glucose with freshly prepared Fehling’s solution, but except in one instance no appreciable amount could be found. The presence of starch was exceptional, and appa- rently in no degree dependent upon the age of the child. The stools of eighteen out of the twenty-four children contained either no starch, or but a trace, i. e., no more than is frequent in the evacuations of a healthy adult upon a mixed diet. Six of these speci- mens were from children of three months or less,— the youngest being but forty-five days old. In many cases the broken and empty cellulose envelopes of the starch granules were clearly discernible. The six infants in whose evacuations a noteworthy amount of starch was present were aged respectively three, four, ten, thirteen, fourteen, and seventeen months. The eldest two were in very bad health. The following is a tabular statement of the age, diet, and appearances of the feces in the children forming the subjects of this study. FECES OF STARCII-FED INFANTS. 445 AN EXAMINATION OF THE FECES OF TWENTY-FOUR STARCH FED INFANTS. No. Name. Age. Food. Starch present. Remarks. 1 Savin, 45 days Condensed milk and cracker dust. None. 2 Joeker, 2 mos. u Traces. 3 McGettinger 2+ “ a U 4 McGowan, 3 “ Twice examined: no fat before in unction, about 10 per cent, after. 5 Ross, 3 “ u u 6 Havs, 3 “ u About i starch 7 Soy, 3 “ u Traces 8 Henwich, 4 “ Corn-starch and milk. U 9 Moore, 4 “ Condensed milk and cracker dust. None Many broken cellu- lose envelopes. 10 Conway, 4+“ it Traces Evidences of potato surreptitiously given 11 Roach, 5 “ About J starch 12 Anxier, 5+ “ U None. 13 Schmitz, McKinley, 5+“ U U Many bacteria. 14 6+“ u u 10 per cent, fat; had had inunctions. 15 Hall, GO + Breast and cracker food. Traces 16 Hensen, 10+“ Condensed milk and cracker dust. More than normal Many bacteria; evi- dences of potato sur- reptitiously given. 17 Devine, 13—“ 20 to 30 per ct. Some glucose present and indications of dextrine; saliva was found to be ineffi- cient. 18 Croncia, 14—“ U Traces. 19 Madden, 14 “ U 20 Boyle, 14 “ a 10 p. ct. starch Sick. 21 Glass, 14+“ u None Except a few large cells containing starch from potato. 22 Kinscher, 17—“ u U 23 Wood, 17—“ u Over | starch Syphilitic; saliva was found to be ineffi- cient. 24 Dane, 18 “ Traces Indications of dex- trine. The facts presented appear to justify the following conclusions:— First, that many infants of under three months can digest starch foods; Second, that the individual variations in this regard 446 RANDOLPH, FECES OF STARCII-FED INFANTS. are so numerous that no broad and general statement can be made as to the period at which infants begin to digest starches; and Third, that the physician can be absolutely certain that a farinaceous ingredient in the diet of a young infant is beneficial only by an examination of the de- jecta under such diet.