With the Authors' Compliments. ('Reprinted from the Cincinnati Lancet* Clinic, May30, i8g6. THE “SINUSOIDAL” CURRENT IN ELECTRO- THERAPY. BY F. W. LANGDON, M.D., CLINICAL PROFESSOR OF NERVOUS DISEASES AT MIAMI MEDiCAL COLLEGE ; NEUROLOGIST TO THE CINCINNATI HOSPITAL AND TO THE OPHTHALMIC HOSPITAL OF CINCINNATI AND W. EDWARDS SCHENCK, M.D., ASSISTANT AT THE NEUROLOGICAL CLINIC, MIAMI MEDICAL COLLEGE. (Read before the Academy of Medicine of Cincinnati, May 18, i8g6. 1lieprinted jrom the Cincinnati Lancet= Clinic, May 30, i8g6. THE “SINUSOIDAL” CURRENT IN ELECTRO- THERAPY. BY F. W. LANGDON, M.D., CLINICAL PROFESSOR OF NERVOUS DISEASES AT MIAMI MEDICAL COLLEGE ; NEUROLOGIST TO THE CINCINNATI HOSPITAL AND TO THE OPHTHALMIC HOSPITAL OF CINCINNATI; AND W. EDWARDS SCHENCK, M.D., ASSISTANT AT THE NEUROLOGICAL CLINIC, MIAMI MEDICAL COLLEGE. (Read before the Academy of Medicine of Cincinnati, May 18, i8g6. THE “ SINUSOIDAL ” CURRENT IN ELECTRO- THERAPY.* BY F. W. LANGDON, M.D., CLINICAL PROFESSOR OK NERVOUS DISEASES AT MIAMI MEDICAL COLLEGE, NEUROLOGIST TO THE CINCINNATI HOSPITAL AND TO THE OPHTHALMIC HOSPITAL OF CINCINNATI; AND W. EDWARDS SCIIENCK, M.D., ASSISTANT AT THE NEUROLOGICAL CLINIC, MIAMI MEDICAL COLLEGE. While all forms of electricity are identical in their ultimate nature, so far as we know, they may differ widely in their physiological and therapeutic effects, as is evident from the familiar differences in results obtained with the galvanic and faradic “ currents,” both as diagnostic and therapeutic agents. That the view once held, that the results observed from electrical treatment were altogether due to a “ psychic ” or “ sug- gestive” influence, is now no longer tenable in many cases, is evident when we consider that the form of current influences materially the result, and this in patients who do not know one current from another. Hence it is evi- dent that the differences noted in these cases at least are positive differences, due to the form in which the electricity is administered. We see an analogy, physiologically, in the differing effects of the two forms of phosphorus, and in the varying action of the various alkaloids which have the opium plant for their common source. Electrically, the now famous Roentgen rays afford another instance of the vary- ing effects derivable from one agent by changing its conditions of production and the relations of its application. The term “ current,” while a mis- nomer, is so firmly ingrained into our nomenclature as to be not easily dis- lodged, even if we possessed a more satisfactory name, which we do not. It is used here, therefore, in the conven- tional sense, as a general term for the varying phenomena due to the action of electro-motive force (“ E. M. F.”). The “wave symbol” is used as a convenient means of expressing graphi- cally one of the differences between “ currents.” The instrument known as the electrograph is used to register these “ waves,” in the same manner as similar instruments register for the physiologist the heart and respiratory movements, the pulse waves, etc. * Thus differences in the “ wave type ” of E. M. F. give rise to the fol- lowing forms of currents recognized by electricians.1 Pulsating Intermittent. Non-in termittent. E. M. F. Continuous Steady. Alternating Symmetrical Dissymmetrical. f Sinusoidal. [ Non-sinusoidal. The “galvanic” current, as com- monly used in medicine, is a “ continu- ous steady” (i.e., direct) current (Fig. 1). This is its form when produced by a battery; when derived from a dynamo it presents a finely undulating non-inter - mittent wave. The “ primary faradic” current presents an alternating dissym- metrical intermittent wave (Fig. a), with abrupt lines of ascent and descent; the “ secondary faradic” an alternating dissymmetrical intermittent wave, with 1 Houston and Kennedy: “Electricity in Electro-Therapeutics.” New York: W. J. Johnston Co., 1896. * Read before the Academy of Medicine of Cincinnati, May 18, 1896. 628 THE “SINUSOIDAL" CURRENT IN ELECTRO-THERAPY. Fig. 1.—“ Continuous steady ” line of flow of “ direct ” galvanic current. Fig. 2.—“Alternating dissymmetrical wave of pri- mary farad’c current. Fig. 3.—Alternating dissymmetrical intermittent wave of secon- dary faradic current. less abrupt lines of ascent and descent (Fig. 3). The “ combined” galvanic and fara- dic current (of DeWatteville) is the wave of the primary faradic to which is added “magnitude” (quantity—am- pereage) by the addition of the “ con- tinuous steady” (direct galvanic) cur- rent, which also eliminates the alterna- tions and dissymmetry. Hence it is described as a “ pulsating intermittent” wave (Fig. 4). The “ static breeze,” “ static spark ” and other forms of frictional electricity in common medical use are pulsating non-intermittent currents of high inten- sity and extremely rapid pulsation, but possess the disadvantage of variability in wave form (dissymmetry) (Fig. 5), and are not controllable as to frequency in a certain and convenient manner. Their uncertainty of action in damp weather is another drawback in prac- tice. The above mentioned are the cur- rents heretofore at the disposal of the profession for diagnostic and therapeutic purposes. The “ sinusoidal” current, the sub- ject of the present paper, presents an “ alternating symmetrical” wave of the form shown in Fig. 6. It is said to have been discovered by d’Arsonval, of Paris, about the year 1892. The accessible literature of the sinu- soidal current is as yet very meagre. D’Arsonval’s communications were pub- lished in the Archives de Physiologic, 1888 to 1893. Kellogg makes some reference to the subject in the “ Inter- THE "SINUSOIDAL". CURRENT IN ELECTRO THERAPT. 629 F10. 4.—Direct pulsating intermittent wave of combined galvanic and primary faradic currents (“ DeWatteville’s current”). Frequency attainable with ordinary spring vibrator = 150 to 300 per second. Fig. 5.—Direct pulsating non-intermittent wave of “ static ” current. Fig. 6.—Alternating symmetrical sinusoidal wave produced by the Kennedy apparatus running at frequency of 480 alternations per second. Rate may be increased to 1920 per second. national System of Electro-Therapeu- tics.” The so-called “ Tesla” current, with which such surprising effects are ob- tained, seems to be a sinusoidal current of unusually high frequency. Various firms have placed on the market apparatuses devised for the pur- pose of producing the sinusoidal cur- rent. The only one of these with which I am familiar is the one here shown, which was constructed for me by the Edison Company, of Orange, N. J. It consists (as shown in Fig. 7) of an alternator, composed of twelve primary and secondary coils, mounted in circu- lar form so as to surround the dentated revolving armature, which is so pro- portioned as to produce the symmetri- cal sinusoidal waves required. Twenty- four alternations are produced at each revolution of the armature. These revolutions are produced by an electric motor of one-twelfth horse power, the speed of which is controll- able within given limits, by means of lamp rheostats. By varying the speed of the motor the frequency of alterna- tions, and consequently of the sinusoidal “ waves,” may be varied from 480 per second, the lowest, increasing by mul- tiples of this amount to 1,920per second, the highest. The current admitted to the primary coils is controlled also by four lamp rheostats, so as to be capable of variation between volts and mul- tiples thereof, up to no volts. As the “ sinusoidal secondary current” so pro- duced passes from the alternator to the binding posts, to be there transferred to 630 THE “SINUSOIDAL” CURRENT IN ELECTR OTHER A P T. the patient, its intensity is regulated by a shunt water-rheostat (the “ Bailey”). The entire apparatus is conveniently operated by the no-volt continuous street current when available. When mounted for an alternating current a different motor and a battery to excite the alternator are required. The application is as simple as any other form of electrical treatment, and requires the same variety of electrodes, care as to gradual increase of current, etc. The physiological peculiarities of the sinusoidal current may be briefly stated as follows: 1. The absence of pain, as compared with the faradic and galvanic currents of equal effect on muscular contraction. The more rapid the alternations (with this apparatus) the less the sensation, other things being equal. While this is not clearly explicable on electrical grounds, it would seem to the writer to be due to inability of the sensory nerves to respond to impressions of such high frequency. In other words, what little we know of the transmission of sensory impulses points to the probability that they are connected in some way with inter-molecular vibrations in the nerve elements, which vibrations have a limit varying with the previous education of the nerve substance. The rapidity of the alternations probably exceeds this limit, hence the failure of the sensory nerves to transmit and register as pain the alternating waves of such enormous frequency. A similar failure of appreciation is seen in the “ Galton whistle” test, the highest pitched notes of which are in- audible to the human ear while heard readily by some animals. 2. The production of muscular con- tractions when faradism fails, i.e., in nerve degenerations following polio- myelitis, etc. The lower frequencies (480 per second) are better adapted to produce muscular contractions. In this feature it resembles the galvanic or direct current, with the advantage of absence of pain. 3. The penetrating power of the cur- rent, which is probably superior to that of any other alternating current, and far exceeds that of the ordinary faradic coil and the “ static” currents. By reason of this great penetration its nutritional value is claimed to be great, and capable of being exerted on deep-seated organs. Hence in motor insufficiency of the stomach, chronic constipation due to bowel atony and relaxed abdominal walls its influence is particularly serviceable. The higher fre- quencies are best adapted to this end. As a consequence of this greater penetrating power also, this current is especially indicated where “general electrization,” either by faradism or galvanism, has heretofore been used. Here the higher frequencies (960,1,440, 1,920 per second) are best used, since they are attended with less muscular contraction and the voltage may be higher. 4. In the hyperesthesias of so-called “ hysterical ” or functional nature, the sinusoidal current finds a field of useful- ness peculiarly its own, not only because it is better borne by the hyper-sensitive structures, but also by reason of its ex- cellent effects on nutrition. It is hardly necessary to say that electricity alone is not a remedy for malnutrition, or a nutrient in any sense. Whatever good effects it may have are doubtless due to the promotion of metabolism and assimi- lation. He who attempts to build up a patient on tonics of any kind, without a correct dietary and hygiene, will find electricity as great a disappointment as any other treatment. The following brief abstracts are selected from a large number of cases treated by us with the sinusoidal cur- rent here referred to, in order to illus- trate its range of action. No attempt is made to select especially favorable results, but failures are recorded in rather greater proportion than they actually bore to the total number of cases treated. ORGANIC DISEASES. Locomotor Ataxia.—This disease has always been considered peculiarly hope- less as regards cure or the material miti- gation of its chief processes, and is con- sequently the favorite example held up by the pessimistic therapeutist to illus- THE “SINUSOIDATT CURRENT IN ELECTRO-THERARr. 631 Fig. 7.—Kennelly Sinusoidal Apparatus, made by the Edison Manufacturing Company. trate the powerlessness of remedies to favorably influence an organic nervous disease. Amongst the chief symptoms which annoy the patient and make his very existence miserable are (i) the “ lightning pains;” (2) the ataxic gait; both of which are the expression of de- generative changes in the peripheral intra-muscular nerve fibres. For the shooting pains the continuous adminis- tration of opiates and coal-tar analgesics is, to say the least, objectionable; and, even though the pains are thus made more bearable, the ataxia is unaffected. The sinusoidal current is the one satisfactory means known to the writer which is capable of absolutely removing the “ lightning pains” and at the same time materially benefiting the ataxia. To do the latter it should, of course, be used early, while some fibres are yet undegenerated. If the results heretofore obtained are verified by a larger and wider experience, it would appear prob- able that we have in this current a most desirable agent in the treatment of tabes. Whether the improved function is due to permanent better nutrition in the peripheral neuron or not, the cases ob- served are too few and the time too short to state positively. It appears to the writer probable that if treated at an early stage the progress of the disease may be materially slowed and the com- fort of the patient vastly increased. In this connection attention may be called to the chloride of aluminium as a remedy for the pains where, for any reason, the patient cannot have the benefit of electrical treatment. This remedy, to which attention was first called by Dr. Gowers, who introduced it to the profession for this purpose rather more than a year ago, we have found extremely serviceable in many cases. It is administered in doses of from two to four grains, dissolved in dialled water, three times a day. 632 THE “SINUSOIDAL” CURRENT IN ELECTRO- THERAPT. On theoretical grounds we have thought it advisable, in the electrical treatment of tabes, to apply one broad electrode at the nape of the neck, the other over the painful areas. For the ataxia, a foot-plate is the best form for the lower pole and a broad neck elec- trode for the upper. The anatomical and pathological reasons for the selec- tion of the above localities are obvious, as the neurons affected in locomotor ataxia have their bodies (the so called cells) in the posterior root ganglia of the cord, while their axis-cylinders (axons), bifurcating, have one extrem- ity in the medulla, the other at the peri- phery. The old idea that the essential pathology of locomotor ataxia was a “ sclerosis” of the posterior columns of the cord is no longer tenable in the light of recent investigations. The disease is now considered pri- marily a degeneration of neurons, prob- ably beginning at the axis-cylinder end- ings. The “sclerosis” is a secondary result of the disappearance of the nerve structures—in short, nature’s way of fill- ing that much-abhorred vacuum. Hence the time to treat the disease is before the degeneration is complete. To do this early diagnosis is essential. The well-established pathological law that the portion of the neuron which first suffers in degenerative disease is that farthest from the (trophic) neuron-body, would furnish a rational indication for the selection of the locali- ties noted, since it is the degenerative process we hope to retard or arrest by improvement in circulation and func- tional activity. Another good reason for the selection of these localities is the fact that in the early stages of the disease some neurons are probably un- affected, and we may hope, by improv- ing the powers of assimilation and nutrition, to influence favorably their function, a “training” process which may be aided by the well-known one of having the patient practice co-ordination by walking a chalk line, practicing manual movements, etc. Case I.—Mr. A., forty-one, manu- facturer. Referred by Dr. F. B. Cross. Married, two healthy children. He- redity good. Chancre twenty years ago. No history of secondary symptoms. Lightning pains very severe for a year past; Argyle - Robertson pupil; lost knee-jerks, girdle anesthesia, seventh to eleventh dorsal vertebra. Ataxia slight. Has been given iodide of potassium freely during past year without good effect of any kind. For six months has taken morphine hypodermically and by mouth for the excruciating pains. Application of sinusoidal current (alternating 480 per second; voltage 55 to from neck to painful points in thighs and legs for ten minutes. Relief of pains complete. Patient slept with- out morphine for the first time in months. The pains returned on the following day, same locality, in less severe form, and were again promptly relieved in the same manner. On the fourth day the pains did not return on the front of thighs, where their intensity had been greatest, but appeared on the back of thighs, lower third. Treatment continued daily for a week, during which time the pains returned twice at night, and patient could not resist the temptation to take morphine, which he had in the house. After ten days’ treatment (from the beginning) the pains ceased to return, patient took no more morphine, and expressed himself as comfortable in every respect, and in better health than for a year or more past. Treatment was continued every other day for a month, by passing current from nape of neck to foot-plate, and patient went to his home in another city in excellent health and spirits. This has continued for the past five months, during which I have seen him about once a month. Very slight pains ap- peared on one occasion before his visit, which one treatment promptly relieved. During his five months’ treatment he has taken the chloride of aluminium in four-grain doses, for a month at a time, and alternating with it phosphorus, strychnia and iron at intervals. His weight has increased eighteen pounds, and he appears in vigorous health. The knee-jerks are still absent, and the Argyle-Robertson pupil present. Ataxia not noticeable, even with eyes closed. THE “STNtJSOtDAL” CURRENT /N ELECTRO THERAPY. 633 No mercury or iodides have been administered at any time while under my care. I do not consider them indi- cated in this disease (L.). Case II.—Mr. B., actor, aged fifty, looks younger. Good physique, spare build, active habits. No history of or visible indications of syphilis. Has Argyle - Robertson pupils, lost knee- jerks, marked static and locomotor ataxia. Gastric crises, no lightning pains. Staggers noticeably even with eyes open; cannot stand or walk with eyes closed. Sinusoidal current passed from nape of neck to foot-plate. Alternations 480, voltage (apparent) 55, time ten minutes. Immediately afterwards was able to walk without staggering, and walked across room with eyes closed, which he could not do before treatment. Im- provement continued for five days under daily treatment. Case still in progress (S.). Case III.—Mr. C., farmer, fifty. Referred to me by Dr. J. B. King. Spare build, well developed. Father died of consumption. Had syphilis ten years ago. Has had grippe. Habits generally good. Has Argyle-Robert- son pupil, lost knee-jerks, marked static and locomotor ataxia with eyes open; cannot stand or walk with eyes closed. High-action gait, cannot walk without cane. Girdle anesthesia below nipple line. No lightning pains. Treatment: Phosphorus, gr. 1/50 t. d.; aluminium chloride, gr. iii, three times a day. Sinusoidal current, neck to foot plate. Alternations 480, voltage 25 to 50. Improvement in ataxia so as to be able to walk without cane and without the “ high-action ” gait. Can be treated but once a week, owing to distance at which he lives. A most unpromising case, but showing marked improvement after three treatments a week apart. Still under treatment (L.). Case IV.—Poliomyelitis Anterior Acuta.—Referred by Dr. A. I. Carson. (Child) D., five and three-quarter years. Onset rapid six weeks ago. Helpless for three weeks, then some power in hands and arms. Can extend and flex thighs, but not legs and feet. Knee- jerks absent. Plantar reflex present. Tactile sensibility present. Electrical examination: No response to faradism of leg and foot muscles. R. D. to galvanism, which causes pain and complaints from child. Sinusoidal current applied to para- lyzed muscles produces contraction, and child does not complain of pain with this current. Continuous treatment advised, but mother would not take trouble to fetch child for treatment, though it was offered gratis. This case is reported in order to emphasize the observation that the sinu- soidal current acts like the galvanic in producing muscular contraction where the nerves are degenerated. It has the additional advantage of being well borne by children because of its slight sensory effects (L.). Case V.—Nuclear Palsy, with An* osmia and Olfactory Paresthesia, ap- parently due to peripheral degeneration of olfactory nerves. Nasal disease ex- cluded by a competent rhinologist.—Mr. E., forty-five. Specific history, for which course of treatment has been taken recently. Smell absent on right side entirely. On left side complains of a constant, very disagreeble odor of something burning. Has ophthalmo- plegia, external and internal. No ataxia. Knee-jerks present normal. His chief complaint is the disagreeable odor above mentioned, which is so persistent and annoying as to cause nausea and loss of appetite. Sinusoidal current applied daily, from nose to nape of neck, at first with partial, later with complete, relief to the peculiar odor; relief would last a day, rarely two days. Immediately after treatment would recognize test odors with both nostrils (peppermint, etc.). After one month’s treatment, with marked improvement in the chief com- plaint, patient ceased his visits. This patient thought he knew so well how to treat his constitutional condition that he looked with contempt on medical advice for that purpose (L.). Case VI. — Sciatic Peri-Neuritis (Syphilis or La Grippe?)—Mr. F., twenty-eight. Dissipated habits. Has secondary syphilis, and recently had an 634 THE “SINUSOIDAL" CURRENT IN ELECTRO-THERAPY. attack of la grippe. Complains of extreme pain in loins and over course of sciatic nerve. Walks with great difficulty, and with a rolling movement from side to side. Prescribed K. I. Ap- plied sinusoidal current to painful areas. Effect almost magical. Pains relieved and gait improved at once. Returned in two days with similar pains less severe. A second application gave complete relief. K. I. continued (S.^). Case VII. — Brachial Neuritis (