Reprinted from The Medical Record of August 21, 1880. THE TWO KINDS OF VIVISECTION— SENT [SECTION AND CALL1SECTION. To the Editor of The Medical Record. Sir :—Is it not time for the distinct verbal recogni- tion of the difference between painful and painless experimentation upon animals ? All well-informed persons are aware that the vast majority of vivisections, in this country at least, are performed under the influence of anaesthetics ; but the enthusiastic zoolaters, who desire to abolish the objective method of teaching physiology, practically ignore this fact and dwell chiefly upon the compara- tively infrequent operations which are attended with pain. Having read the arguments upon both sides and had some correspondence with leaders of the anti- vivisection movement, I have been led to think that the discussion may be simplified, and a right conclu- sion sooner reached, if we adopt new terms corre- sponding to the two kinds of experimentation. To use words with no warrant of ideas may be foolish, but it is not necessarily a mark of wisdom to refrain from the employment of terms which have a real significance. Let rrs consider an analogous case. Aside from color and size, the cat and the leopard are almost identical, and are commonly regarded as two species of one genus. Suppose a community to be unac- quainted with the cat, but to have suffered from the depredations of the leopard, which they call felts. Now, suppose some domestic cats to be introduced and to multiply as is their wont. In the first place, for a time at least, it is probable that the same name, fells, would be applied to the smaller animal, with perhaps a qualifying word. In the second place, should there be certain persons, both devoid of interest in the cats and tilled with pity for the mice devoured by them, is it not likely that they would endeavor to include the cats under any ban which might be pronounced against the leopards? Would they not be apt to succeed, especially with the more ignorant and impressionable members of the community, so long as they could assert without contradiction that the “mouse-eater” was only a fells upon a smaller scale ? Would not even the reputa- 2 tion of tlie leopards suffer by reason of the multitude of the cats thus associated with them? In short, would full justice be done to either animal until their differences of disposition should be admit- ted to outweigh their likeness of form and structure, and be recognized by the use of distinctive names? In like manner there are those who ignorantly or wilfully persuade themselves and others that all ex- periments upon animals are painful because some of them are now, and most of them were in former times; also, that painful experiments are common because vivisection in some form is generally prac- tised. It is all vivisection, and as such it is “cruel, revolting, or brutalizing.” Having waited long in the hope that some candid discussion of the whole subject might contain the needed terms, I venture to suggest that painful vivi- section be known as sentisection, and painless vivisec- tion as callisection. The etymology of the former word is obvious ; the distinctive element of the latter is the Latin callus, which, in a derived sense, may denote a nervous condition unrecognized, strictly speaking, by the ancients. Some idea of the relative numbers of callisection- ists and sentisectionists may be gained from the fact that I have been teaching physiology in a university for twelve years, and for half that time in a medical school; yet I have never performed a sentisection, unless under that head should be included the drowning ol cats, and the application of water at the temperature of 60° 0. (140° F.), with the view to as- certain whether such treatment would be likely to succeed with human beings. I think that even elementary physiological instruc- tion is incomplete without callisection, but that senti- section should be the unwelcome prerogative of the very few whose natural and acquired powers of body and mind qualify them above others to determine what experiments should be done, to perform them properly, and .to wisely interpret the results. Such men, deserving alike of the highest honor and the deepest pity, should exercise their solemn office not only unrestrained by law, but upheld by the general sentiment of the profession and the public. Burt G. Wilder, M.D., Prof. Physiology, etc., Cornel] University, and Medical Sohuol of Maine.