10.

ll.

12.

BIBLIOGRAPHY

Marshall Nirenberg

Nirenberg, M.W. and Hogg, J.F.: On the mode of hexose
uptake by ascites tumor cells. J. Am. Chem. Soc., 78 6210-
6211 (1956).

Nirenberg, M.W. and Hogg, J.F.: Inhibition of anaerobic
glycolysis in Ehrlich ascites tumor cells by 2-deoxy-D-glucose.
Cancer Research, 18: 518-521 (1958).

Nirenberg, M.W. and Hogg J.F.: Hexose transport in ascites
tumor cells. J. Am. Chem. Soc., 80: 4407-4412 (1958).

Nirenberg, M.W.: An enzymic defect in ascites-tumor cells.
Biochem. Biophys. Acta, 30: 203-204 (1958).

Nirenberg, M.W.: A biochemical characteristic of ascites tumor
cells. J. Biol. Chem., 234: 3088-3093 (1959).

Nirenberg, M.W. and Jakoby, W.B.: Enzymatic utilization of g-
hydroxybutyric acid. J. Biol. Chem., 235: 954-960 (1960).

Nirenberg, M.W.: The induction of two enzymes by one inducer; a
test case for shared genetic information. Fed. Proc., 19: 42
(1960).

Nirenberg, M.W. and Jakoby, W.B.: On the sites of attachment
and reaction of aldehyde dehydrogenases. Proc. Natl. Acad. Sci.
USA, 46: 206-212 (1960).

Nirenberg, M.W. and Jakoby, W.B.: Constraints in the
determination of active-centre topography. Nature, 188: 747-748
(1960).

Nirenberg, M.W. and Matthaei, H.: The dependence of cell-free
protein synthesis in E. coli upon naturally occurring or
synthetic template RNA. in Biological Structure and Function at
the Molecular Level, Engelhardt, V.A. (Ed.), The MacMillan Co.,
New York, Proc. Fifth Int. Cong. Biochem., Vol. I, Moscow, 1961,
pp. 184-189.

Matthaei, H. and Nirenberg, M.W.: The dependence of cell-free
protein synthesis in E. coli upon RNA prepared from ribosomes.
Biochem. Biophys. Res. Commun., 4: 404-408 (1961).

Matthaei, J.H. and Nirenberg, M.W.: Characteristics and
stabilization of DNAase sensitive protein synthesis in E. coli
extracts. Proc. Natl. Acad. Sci. USA, 47: 1580-1588 (1961).

 

1/19/00
13.

14.

15.

16.

17.

18.

19.

20.

21.

22.

23.

24.

Nirenberg, M.W. and Matthaei, J.H.: The dependence of cell-free
protein synthesis in E. coli upon naturally occurring or
synthetic polyribonucleotides. Proc. Natl. Acad. Sci. USA, 47:
1588-1602 (1961).

Martin, R.C., Matthaei, J.H., Jones, O.W. and Nirenberg, M.W.:
Ribonucleotide composition of the genetic code. Biochem.
Biophys. Res. Commun., 6: 410-414 (1961/62).

Matthaei, J.H., Jones, O.W., Martin, R.G. and Nirenberg, M.W.:
Characteristics and composition of RNA coding units. Proc.
Natl. Acad. Sci. USA, 48: 666-677 (1962).

Tsugita, A., Fraenkel-Conrat, H., Nirenberg, M.W. and Matthaei,
J.H.: Demonstration of the messenger role of viral RNA. Proc.
Natl. Acad. Sci. USA, 48: 846-853 (1962).

Barondes, S.H. and Nirenberg, M.W.: Fate of synthetic
polynucleotide directing cell-free protein synthesis. I.
Characteristics of degradation. Science, 138: 810-813 (1962).

Barondes, S.H. and Nirenberg, M.W.: Fate of synthetic
polynucleotide directing cell-free protein synthesis. II.
Association with ribosomes. Science, 138: 813-817 (1962).

Nirenberg, M.W., Matthaei, J.H. and Jones, O.W.: An
intermediate in the biosynthesis of polyphenylalanine directed
by synthetic template RNA. Proc. Natl. Acad. Sci. USA, 48: 104-
109 (1962).

Jones, O.W., Jr. and Nirenberg, M.W.: Qualitative survey of RNA
codewords. Proc. Natl. Acad. Sci. USA, 48: 2115-2123 (1962).

Nirenberg, M.W., Matthaei, J.H., Jones, O.W., Martin, R.G. and
Barondes, S.H.: Approximation of genetic code via cell-free
protein synthesis directed by template RNA. Fed. Proc. Symp.,
22: 55-61 (1963).

Nirenberg, M.W.: Cell-free protein synthesis directed by
messenger RNA. in Methods in Enzymology, Eds. S.P. Colowick and
N.A. Kaplan (1963), Academic Press, New York, Vol. 6, pp. 17-
23.

Nirenberg, M.W. and Jones, O.W., Jr.: The current status of the
RNA code in Symposium on Informational Macromolecules, H. Vogel
(Ed.), 1963, Academic Press, New York, New York, pp. 451-465.

Singer, M.F., Jones, O.W. and Nirenberg, M.W.: The effect of
secondary structure on the template activity of
polyribonucleotides. Proc. Natl. Acad. Sci. USA, 49: 392-399
(1963).

1/19/00
25.

26.

27.

28.

29.

30.

31.

32.

33.

34.

35.

36.

Nirenberg, M.W., Jones, O.W., Leder, P., Clark, B.F.C.,
Sly, W.S. and Pestka, S.: On the coding of genetic information.
Cold Spring Harbor Symp. on Quant. Biol., 28: 549-557 (1963).

Leder, P., Clark, B.F.C., Sly, W.S., Pestka, S. and Nirenberg,
M.W.: Cell-free peptide synthesis dependent upon synthetic
oligodeoxynucleotides. Proc. Natl. Acad. Sci. USA, 50: 1135-
1143 (1963).

Nirenberg, M.W.: The Genetic Code: II. Scientific American,
208: 80-94 (1963).

Nirenberg, M.W.: Nucleic acids in relation to the coding of
genetic information in Brain Function, Vol. II: RNA and Brain
Function; Memory and Learning. Mary A.B. Brazier (Ed.). UCLA
Forum held in 1962, Univ. of Calif. Press, Berkeley and Los
Angeles, pp. 5-28, (1964).

Bryne, R., Levin, J.C., Bladen, H.A. and Nirenberg, M.W.: The
in vitro formation of a DNA-ribosome complex. Proc. Natl. Acad.
Sci. USA, 52: 140-148 (1964).

Eiserling, F., Levin, J.G., Byrne, R., Karlsson, U., Nirenberg,
M.W. and Sj6 strand, F.S.: Polyribosomes and DNA-dependent
amino acid incorporation in Escherichia coli extracts. J. Mol.
Biol., 10: 536-540 (1964).

Nirenberg, M.W. and Leder, P.: RNA codewords and protein
synthesis. I. The effect of trinucleotides upon the binding of
SRNA to ribosomes. Science, 145: 1399-1407 (1964).

Leder, P. and Nirenberg, M.W.: RNA codewords and protein
synthesis. II. Nucleotide sequence of a valine RNA codeword.
Proc. Natl. Acad. Sci. USA, 52: 420-427 (1964).

Leder, P. and Nirenberg, M.W.: RNA codewords and protein
synthesis. III. On the nucleotide sequence of a cysteine and a
leucine RNA codeword. Proc. Natl. Acad. Sci., 52: 1521-1529

. (1964).

Nirenberg, M.W.: Protein synthesis and the RNA code. in Harvey
Lectures, Series 59, pp. 155-185 (1964).

Aach, H.G., Funatsu, G., Nirenberg, M.W. and Fraenkel-Conrat,
H.: Further attempts to characterize products of TMV-RNA-
directed protein synthesis. Biochemistry, 3: 1362-1366 (1964).

Bernfield, M.R. and Nirenberg, M.W.: RNA codewords and protein
synthesis. IV. The nucleotide sequences of multiple codewords
for phenylalanine, serine, leucine and proline. Science, 147:
479-484 (1965).

1/19/00
37.

38.

39.

40.

41.

42.

43.

44.

45.

46.

47.

Pestka, S., Marshall, R. and Nirenberg, M.W.: RNA codewords and
protein synthesis. V. Effect of streptomycin on the formation

of ribosome sRNA complexes. Proc. Natl. Acad. Sci., 53: 639-646
(1965).

Bladen, H.A., Byrne, R., Levin, J.G. and Nirenberg, M.W.: An
electron microscopic study of a DNA-ribosome complex formed in
vitro. J. Mol. Biol., 11: 78-83 (1965).

Millar, D.B.S., III, Cukier, R. and Nirenberg, M.W.:
Interaction of E. coli ribosomal RNA with synthetic
polynucleotides. Sedimentation properties, and thermal
stability as measured by fluorescence polarization.
Biochemistry, 4: 976-985 (1965).

Trupin, J.S., Rottman, F.M., Brimacombe, R.L.C., Leder, P.,
Bernfield, M.R.and Nirenberg, M.W.: RNA codewords and protein
synthesis. VI. On the nucleotide sequence of degenerate codeword
sets for isoleucine, tryosine, asparagine, and lysine. Proc.
Natl. Acad. Sci. USA, 53: 807-811 (1965).

Nirenberg, M., Leder, P., Bernfield, M., Brimacombe, R., Trupin,
J., Rottman, F. and O'Neal, C.: RNA codewords and protein
synthesis. VII. On the general nature of the RNA code. Proc.
Natl. Acad. Sci., 53: 1161-1168 (1965).

Brimacombe, R., Trupin, J., Nirenberg, M., Leder, P., Bernfield,
M. and Jaouni, T.: RNA codewords and protein synthesis. VIII.
Nucleotide sequences of synonym codons for arginine, valine,
cysteine, and alanine. Proc. Natl. Acad. Sci. USA, 54: 954-960
(1965).

Kellogg, D.A., Doctor, B.P., Loebel, J.E. and Nirenberg, M.W.:
RNA codons and protein synthesis. IX. Synonym codon
recognition by multiple species of valine-, alanine-, and
methionine-sRNA. Proc. Natl. Acad. Sci., 55: 912-919 (1966).

Trupin, J., Dickerman, H., Nirenberg, M. and Weissbach, H.:
Formylation of amino acid analogues of methionine sRNA.
Biochem. Biophys. Res. Common., 24: 50~55 (1966).

Jones, O.W., Jr. and Nirenberg, M.W.: Degeneracy in the amino
acid code. Biochem. Biophys. Acta., 119: 400-406 (1966).

Grunberger, D., O'Neal, C. and Nirenberg, M.: Stimulation of
amino acid incorporation into protein by polyuridylic-8-
azaguanylic acid. Biochem. Biophys. Acta., 119: 581-585 (1966).

Anderson, W.F. and Nirenberg, M.: The genetic code and protein
synthesis. in Handbook of Biochem. and Biophys., H.C. Damm, P.kK.
Besch, A.J. Goldwyn (Eds.), Cleveland and New York, World
Publishing Company, pp. 96-108 (1966).

1/19/00
48.

49.

50.

51.

52.

53.

54A.

54B.

55.

56.

57.

58.

Pestka, S. and Nirenberg, M.: Regulatory mechanisms and protein
synthesis recognition. X. Codon recognition of 30 S$ ribosomes.
J. Mol. Biol., 21: 145-171 (1966).

Rottman, F. and Nirenberg, M.: RNA codons and protein
synthesis. XI. Template activity of modified RNA codons. J.
Mol. Biol., 21: 555-570 (1966).

Nirenberg, M., Caskey, T., Marshall, R., Brimacombe, R.,
Kellogg, D., Doctor, B., Hatfield, D., Levin, J., Rottman, F.,
Pestka, S., Wilcos, M. and Anderson, F.: The RNA code and
protein synthesis. Cold Spring Harbor Symp. on Quant. Biol.,
31: 11-24 (1966).

Pestka, S. and Nirenberg, M.: Codeword recognition of 30 S$
ribosomes. Cold Spring Harbor Symp. on Quant. Biol., 31: 641-656
(1966).

Marshall, R.E., Caskey, C.T. and Nirenberg, M.: RNA codewords
and protein synthesis. XII. Fine structure of RNA codewords
recognized by bacterial, amphibian, and mammalian transfer RNA.
Science, 155: 820-826 (1967).

Nirenberg, M.: The genetic code in The Neurosciences, Quarton,
G.C., Melnechuk, T. and Schmitt, F.O. (Eds.), New York, The
Rockefeller University Press, pp. 143-152 (1967).

Nirenberg, M.: Man's power to shape his own biologic destiny -
will society be prepared to use it wisely? Quarterly Bulletin of
Research Corporation, Spring 1967. (Part reproduced as an
editorial in Science).

Nirenberg, M.: Will society be prepared? Science, 157: 633
(1967).

Nirenberg, M.W., Caskey, C.T. and Levin, J.G.: RNA codon
recognition. Seventh International Congress of Biochemistry,
(Japan) Suppl. 1, p. 1068 (1967).

Kano-Sueoka, T., Nirenberg, M. and Sueoka, N.: Effect of
bacteriophage infection upon the specificity of leucine transfer
RNA for RNA codewords. J. Mol. Biol., 35, 1-12 (1968).

Levin, J.G. and Nirenberg, M.: RNA codons and protein
synthesis. XIII. RNA codon recognition by deacylated tRNA and
aminoacyl tRNA. J. Mol. Biol., 34: 467-480 (1968).

Caskey, C.T., Beaudet, A. and Nirenberg, M.: RNA codons and
protein synthesis. 15. Dissimilar responses of mammalian and
bacterial transfer RNA fractions to mRNA codons. J. Mol. Biol.,
37: 99-118 (1968).

1/19/00
59.

60.

61.

62.

63.

64.

65.

66.

67.

68.

69.

70.

71.

Wilcox, M. and Nirenberg, M.: Transfer RNA as a cofactor
coupling amino acid synthesis with that of protein. Proc. Natl.
Acad. Sci. USA, 61: 229-236 (1968).

Caskey, C.T., Tompkins, R., Scolnick, E., Caryk, T. and
Nirenberg, M.: Sequential translation of trinucleotide codons
for the initiation and termination of protein synthesis.
Science, 162: 135-138 (1968).

Scolnick, E., Tompkins, R., Caskey, T. and Nirenberg, M.:
Release factors differing in specificity for terminator codons.
Proc. Natl. Acad. Sci. USA, 61: 768-774 (1968).

Nirenberg, M.: Genetic Memory. J. Am. Med. Assn., 206: 1973-
1977 (1968).

Nirenberg, M.: The Genetic Code in Les Prix Nobel en 1968.
Nobel Foundation, Stockholm, P.A. Norstedt and S6 ner, pp. 221-
241, (1969).

Nirenberg, M.W.: On the translation of the genetic code in
Biology and Physical Sciences, Devons, S. (Ed.), N.Y., Columbia
University Press, 1969, pp. 57-73, (1969).

Marshall, R. and Nirenberg, M.: RNA codons recognized by
transfer RNA from amphibian embryos and adults. Developmental
Biology, 19: 1-11 (1969).

Gartland, W.J., Ishida, T., Sueoka, N. and Nirenberg, M.W.:
Coding properties of two conformations of tryptophanyl-tRNA in
Escherichia coli. J. Mol. Biol., 44: 403-413 (1969).

Nelson, P., Ruffner, W. and Nirenberg, M.: Neuronal tumor cells
with excitable membranes grown in vitro. Proc. Natl. Acad. Sci.
USA, 64: 1004-1010 (1969).

Nirenberg, Von M.: Der genetische code (Nobel-Vortrag). Angew.
Chemie, 81: 1017-1027 (1969).

Seeds, N.W., Gilman, A.G., Amano, T. and Nirenberg, M.W.:
Regulation of axon formation by clonal lines of a neuronal
tumor. Proc. Natl. Acad. Sci. USA, 66: 160-167 (1970).

Nirenberg, M.: The flow of information from gene to protein in
Aspects of Protein Biosynthesis, Part A., Anfinsen, C.B., Jr.,
(Ed.), New York, Academic Press, Inc., pp. 215-246, 1970.

Blume, A., Gilbert, F., Wilson, S., Farber, J., Rosenberg, R.
and Nirenberg, M.: Regulation of acetylcholinesterase in
neuroblastoma cells. Proc. Natl. Acad. Sci. USA, 67: 786-792
(1970).

1/19/00
72.

73.

74.

75.

76.

77.

78.

79.

80.

81.

82.

83.

Smrt, J., Kemper, W., Caskey, T. and Nirenberg, M.: Template
activity of modified terminator codons. J. Biol. Chem., 245:
2753-2757 (1970).

Kan, J., Nirenberg, M.W. and Sueoka, N.: Coding specificity of
Escherichia coli leucine transfer ribonucleic acids and effect
of bacteriophage T2 infection. J. Mol. Biol., 52: 179-193
(1970).

Hatfield, D. and Nirenberg, M.: Binding of radioactive
oligonucleotides to ribosomes. Biochem., 10: 4318-4323 (1971).

Minna, J., Nelson, P., Peacock, J., Glazer, D. and Nirenberg,
M.: Genes for neuronal properties expressed in neuroblastoma x
L cell hybrids. Proc. Natl. Acad. Sci. USA, 68: 234-239 (1971).

Gilman, A.G. and Nirenberg, M.: Effect of catecholamines on the
adenosine 3':5'-cyclic monophosphate concentrations of clonal
satellite cells of neurons. Proc. Natl. Acad. Sci. USA, 68:
2165-2168 (1971).

Gilman, A.G. and Nirenberg, M.: Regulation of adenosine 3':5'-
cyclic monophosphate metabolism in cultured neuroblastoma cells.
Nature, 234: 356-358 (1971).

Amano, T., Richelson, E. and Nirenberg, M.: Neurotransmitter
synthesis by neuroblastoma clones. Proc. Natl. Acad. Sci. USA,
69: 258-263 (1972).

Peacock, J., Minna, J., Nelson, P. and Nirenberg, M.: Use of
aminopterin in selecting electrically active neuroblastoma
cells. Experimental Cell Research, 73: 367-377 (1972).

Minna, J., Glazer, D. and Nirenberg, M.: Genetic dissection of
neural properties using somatic cell hybrids. Nature New
Biology, 235: 225-231 (1972).

Wilson, S.H., Schrier, B.K., Farber, J.L., Thompson, E.J.,
Rosenberg, R.N., Blume, A.J. and Nirenberg, M.W.: Markers for
gene expression in cultured cell from the nervous system. J.
Biol. Chem., 247: 3159-3169 (1972).

Vogel, Z., Sytkowsky, A.J. and Nirenberg, M.W.: Acetylcholine
receptors of muscle grown in vitro. Proc. Natl. Acad. Sci. USA,
69: 3180-3184.

Thompson, E.J., Wilson, S.H., Schuette, W.H., Whitehouse, W.C. a
nd Nirenberg, M.W.: Measurement of the rate and velocity of
movement by single heart cells in culture. Am. J. of
Cardiology, 32: 162-166 (1973).

1/19/00
84.

85.

86.

87.

88A.

88B.

88C.

89.

90.

91.

92.

93.

Catterall, W.A. and Nirenberg, M.: Sodium uptake associated
with activation of action potential ionophores of cultured
neuroblastoma muscle cells. Proc. Natl. Acad. Sci. USA, 70:
3759-3763 (1973).

Sytkowsky, A.J., Vogel, Z. and Nirenberg, M.W.: Development of
acetylcholine receptor clusters on cultured muscle cells. Proc.
Natl. Acad. Sci. USA, 70: 270-274 (1973).

Greene, L.A., Sytkowsky, A.J., Vogel, Z. and Nirenberg, M.W.:
a-Bungarotoxin used as a probe for acetylcholine receptors of
cultured neurons. Nature, 243: 163-166 (1973).

Chalazonitis, A., Greene, L.A. and Nirenberg, M.:
Electrophysiological characteristics of chick embryo sympathetic
neurons in dissociated cell culture. Brain Research, 68: 235-
252 (1974).

Schrier, B.K., Wilson, S.H., Nirenberg, M.: Cultured cell
systems and methods for neurobiology in Methods in Enzymology,
Vol. 32, Part B, pp. 765-783, Fleischer, S. and Packer, L.
(Eds.). Academic Press, New York (1974).

Hamprecht, B., Amano, T. and Nirenberg, M.: Choline
acetyltransferase. Assay 2. Ibid. pp. 783-785 (1974).

Richelson, E. and Nirenberg, M. Tyrosine hydroxylase assay.
Ibid. pp. 785-788 (1974).

Klee, W.A. and Nirenberg, M.: A neuroblastoma x glioma hybrid
cell line with morphine receptors. Proc. Natl. Acad. Sci. USA,
71: 3474-3477 (1974).

Breakefield, X.0. and Nirenberg, M.: Selection for
neuroblastoma cells that synthesize certain transmitters. Proc.
Natl. Acad. Sci. USA, 71: 2530-2533 (1974).

Klee, W.A., Sharma, S.K. and Nirenberg, M.: Opiate receptors as
regulators of adenylate cyclase. Life Sci., 16: 1869-1874
(1975), in The Opiate Narcotics., Neurochemical Mechanisms in
Analgesia and Dependence. Goldstein, A. et al. (Eds.), Pergamon
Press, New York, pp. 117-122 (1975).

Thompson, E.J., Griffith, J.M., Schoenberg, D.G. and Nirenberg,
M.W.: An improved method for extracellular recording of action
potentials from single cultured neuroblastoma cells. Med. Biol.
Eng., 13, 104-106 (1975).

Sharma, S.K., Nirenberg, M. and Klee, W.A.: Morphine receptors
as regulators of adenylate cyclase activity. Proc. Natl. Acad.
Sci. USA, 72: 590-594 (1975).

1/19/00
94,

95.

96.

97.

98.

99.

100.

101.

102.

103.

104.

105.

106.

Sharma, S.K., Klee, W.A. and Nirenberg, M.: Dual regulation of
adenylate cyclase accounts for narcotic dependence and
tolerance. Proc. Natl. Acad. Sci. USA, 72: 3092-3096 (1975).

Matsuzawa, H. and Nirenberg, M.: Receptor-mediated shifts in
cGMP and cAMP levels in neuroblastoma cells. Proc. Natl. Acad.
Sci. USA, 72: 3472-3476 (1975).

Nirenberg, M.W.: Coding of neural information by neuroblastoma
cells. in Talwar, G.P. (Ed.): Regulation of Growth and
Differentiated Function in Eukaryote Cells. New York, Raven
Press, pp. 537-539 (1975).

Greene, L.A., Shain, W., Chalazonitis, A., Breakefield, X.,
Minna, J., Coon, H.G. and Nirenberg, M.: Neuronal properties of
hybrid neuroblastoma x sympathetic ganglion cells. Proc. Natl.
Acad. Sci. USA, 72: 4923-4927 (1975).

Nelson, P., Christian, C. and Nirenberg, M.: Synapse formation
between clonal neuroblastoma x glioma hybrid cells and striated
muscle cells. Proc. Natl. Acad. Sci. USA, 73: 123-127 (1976).

Vogel, Z. and Nirenberg, M.: Localization of acetylcholine
receptors during synaptogenesis in retina. Proc. Natl. Acad.
Sci. USA, 73: 1806-1810 (1976).

Vogel, Z. Daniels, M.P. and Nirenberg, M.: Synapse and
acetylcholine receptor synthesis by neurons dissociated from
retina. Proc. Natl. Acad. Sci. USA, 73: 2370-2374 (1976).

Lampert, A., Nirenberg, M. and Klee, W.A.: Tolerance and
dependence evoked by an endogenous opiate peptide. Proc. Natl.
Acad. Sci. USA, 73: 3165-3167 (1976).

Klee, W.A. and Nirenberg, M.: Mode of action of endogenous
Opiate peptides. Nature, 263: 609-612 (1976).

De Mello, F.G., Bachrach, U. and Nirenberg, M.: Ornithine and
glutamic acid decarboxylase activities in the developing chick
retina. J. Neurochem., 27: 847-851 (1976).

Puro, D.G. and Nirenberg, M.: On the specificity of synapse
formation. Proc. Natl. Acad. Sci. USA, 73: 3544-3548 (1976).

Klee, W.A., Lampert, A. and Nirenberg, M.: Dual regulation of
adenylate cyclase by endogenous opiate peptides in Kosterlitz,
H. (Ed.): Opiates and Endogenous Opioid Peptides. Amsterdam,
Elsevier/North-Holland Biomedical Press, 1976, pp. 153-159.

Goldstein, A., Cox, B.M., Klee, W.A. and Nirenberg, M.:
Endorphin from pituitary inhibits cyclic AMP formation in
homogenates of neuroblastoma x glioma hybrid cells. Nature,
265: 362-363 (1977). 1/19/00
107.

108.

109.

110.

lil.

112.

113.

114.

115.

116.

117.

118.

Chalazonitis, A., Minna, J.D. and Nirenberg, M.: Expression and
properties of acetylcholine receptors in several clones of mouse
neuroblastoma x L cell somatic hybrids. Exp. Cell Res., 105:
269-280 (1977).

Christian, C.N., Nelson, P.G., Peacock, J. and Nirenberg, M.:
Synapse formation between two clonal cell lines. Science, 196:
995-998 (1977).

Agarwal, N.S., Hruby, V.J., Katz, R., Klee, W. and Nirenberg,

M.: Synthesis of leucine enkephalin derivatives: Structure-

function studies. Biochem. Biophys. Res. Commun., 76: 129-135
(1977).

Giagnoni, G., Sabol, S.L. and Nirenberg, M.: Synthesis of
Opiate peptides by a clonal pituitary tumor cell line. Proc.
Natl. Acad. Sci. USA, 74: 2259-2263 (1977).

Sharma, S.K., Klee, W.A. and Nirenberg, M.: Opiate-dependent
modulation of adenylate cyclase. Proc. Natl. Acad. Sci. USA,
74: 3365-3369 (1977).

Puro, D.G., De Mello, F.G. and Nirenberg, M.: Synapse turnover:
the formation and termination of transient synapses. Proc.
Natl. Acad. Sci. USA, 74: 4977-4981 (1977).

Sugiyama, H., Daniels, M.P. and Nirenberg, M.: Muscarinic
acetylcholine receptors of the developing retina. Proc. Natl.
Acad. Sci. USA, 74: 5524-5528 (1977).

McGee, R., Simpson, P., Christian, C., Mata, M., Nelson, P. and
Nirenberg, M.: Regulation of acetylcholine release from
neuroblastoma x glioma hybrid cells. Proc. Natl. Acad. Sci.
USA, 75: 1314-1318 (1978).

Nathanson, N.M., Klein, W.L. and Nirenberg, M.: Regulation of
adenylate cyclase activity mediated by muscarinic acetylcholine
receptors. Proc. Natl. Acad. Sci. USA, 75: 1788-1791 (1978).

Ruffolo, R.R., Jr., Eisenbarth, G.S., Thompson, J.M. and
Nirenberg, M.: Synapse turnover: A mechanism for acquiring
synaptic specificity. Proc. Natl. Acad. Sci. USA, 75: 2281-2285
(1978).

MacDermot, J. and Nirenberg, M.: Turnover of opiate receptors
in neuroblastoma x glioma hybrid cells. FEBS Lett., 90: 345-347
(1978).

Nirenberg, M.: Studies on synapse formation and opiate
dependence. National Cancer Institute Monograph, 48: 339-342
(1978).

1/19/00
119.

120.

121.

122.

123.

124.

125.

126.

127.

128.

Nelson, P.G., Christian, C.N., Daniels, M.P., Henkart, M.,
Bullock, P., Mullinax, D. and Nirenberg, M.: Formation of
synapses between cells of a neuroblastoma x glioma hybrid clone
and mouse myotubes. Brain Research, 147: 245-259 (1978).

Christian, C.N., Nelson, P.G., Bullock, P., Mullinax, D. and
Nirenberg, M.: Pharmacologic responses of cells of a
neuroblastoma x glioma hybrid clone and modulation of synapses
between hybrid cells and mouse myotubes. Brain Research, 147:
261-276 (1978).

Eisenbarth, G.S., Ruffolo, R.R., Walsh, F.S. and Nirenberg, M.:
Lactose sensitive lectin of chick retina and spinal cord.
Biochem. Biophys. Res. Commun., 83: 1246-1252 (1978).

Burgermeister, W., Kline, W.L., Nirenberg, M. and Witkop, B.:
Comparative binding studies with cholinergic ligands and
histrionicotoxin at muscarinic receptors of neural cell lines.
J. Mol. Pharm., 14: 751-767 (1978).

Sabol, S.L. and Nirenberg, M.: Regulation of adenylate cyclase
of neuroblastoma x glioma hybrid cells by a-adrenergic
receptors, I. Inhibition of adenylate cyclase mediated by a-
receptors. J. Biol. Chem., 254: 1913-1920 (1979).

Sabol, S.L. and Nirenberg, M.: Regulation of adenylate cyclase
of neuroblastoma x glioma hybrid cells by a-adrenergic
receptors, II. Long-lived increase of adenylate cyclase
activity mediated by a-receptors. J. Biol. Chem., 254: 1921-
1926 (1979).

MacDermot, J., Higashida, H., Wilson, S.P. Matsuzawa, H., Minna,
J. and Nirenberg, M.: Adenylate cyclase and acetylcholine
release regulated by separate serotonin receptors of somatic
cell hybrids. Proc. Natl. Acad. Sci. USA, 76: 1135-1139 (1979).

Eisenbarth, G.S., Walsh, F.S. and Nirenberg, M.: Monoclonal
antibody to a plasma membrane antigen of neurons. Proc. Natl.
Acad. Sci. USA, 76: 4913-4917 (1979).

Klein, W.L., Nathanson, N. and Nirenberg, M.: Muscarinic
acetylcholine receptors regulation by accelerated rate of
receptor loss. Biochem. Biophys. Res. Commun., 90: 506-512
(1979).

Wilkening, D. and Nirenberg, M.: Lipid requirement for long-
lived morphine-dependent activation of adenylate cyclase of
neuroblastoma x glioma hybrid cells. J. Neurochem., 34: 321-326
(1980).

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129.

130.

131.

132A

132B

133.

134.

135.

136.

Nirenberg, M., Wilson, S., Higashida, H., Thompson, J.,
Eisenbarth, G., Walsh, F., Rotter, A., Kenimer, J. and Sabol,
S.: Synapse plasticity in Cellules, Nerveuses, Transmetteurs et
Comportement, Edited by Rita Levi-Montalcini, Pontificiae
Academiae Scientarvm Scripta Varia, 45: 123-127 (1980).

McGee, R., Jr., Smith, C., Christian, C., Mata, M., Nelson, P.
and Nirenberg, M.: A new capillary tube system for measuring
the uptake and release of materials from cultured cells. Anal.
Biochem., 101: 320-326 (1980).

Wilkening, D., Sabol, S.L. and Nirenberg, M.: Control of opiate
receptor-adenylate cyclase interactions by calcium ions and
guanosine-5 -triphosphate. Brain Research, 189: 459-466 (1980).

Trisler, G.D ., Schneider, M.D. and Nirenberg, M.: A topographic
gradient of molecules in retina can be used to identify neuron
position. Proc. Natl. Acad. Sci. USA, 78: 2145-2149 (1981).

This paper also has been reproduced in the following:

Trisler, G. David, Michael D. Schneider and Marshall Nirenberg:
A topographic gradient of molecules in retina can be used to
identify neuron position in Patterson, P.H. and Purves, D.
(Ed.): Readings In Developmental Neurobiology. Cold Spring
Harbor Laboratory, 1982, pp. 513-517.

Trisler, G.D., Schneider, M.D. and Nirenberg, M.: Topographic
gradient of cell-membrane molecules in avian neural retina
detected with monoclonal antibody in Ocular Size and Shape:
Regulation During Development, Hilfer, S.R. and Sheffield, J.B.
(Eds.), Springer-Verlag, N.Y., p. 141-161 (1981).

De Blas, A.L., Busis, N.A. and Nirenberg, M.: Monoclonal
antibodies to synaptosomal membrane molecules in Monoclonal
Antibodies Against Neuronal Antigens, McKay, R., Raff, M.C. and
Reichardt, L.F. (Ed.), Cold Spring Harbor Reports in the
Neurosciences Vol. 2, Cold Spring Harbor Laboratory, N.Y.
(1981), pp. 181-191.

Trisler, G.D., Schneider, M.D., Moskal, J.R. and Nirenberg, M.:
A gradient of molecules in avian retina with dorsoventral
polarity in Monoclonal Antibodies Against Neuronal Antigens,
McKay, R., Raff, M.C. and Reichardt, L.F. (Ed.), Cold Spring
Harbor Reports in the Neurosciences Vol. 2, Cold Spring Harbor
Laboratory, N.Y. (1981), pp. 231-257.

Kenimer, J. and Nirenberg, M.: Desensitization of adenylate

cyclase to prostaglandin E, or 2-Chloroadenosine. Mol. Pharm.,
20: 585-591 (1981)

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137.

138.

139.

140.

141.

142.

143.

144.

145.

Hirata, F., Del Carmine, R., Nelson, C.A., Axelrod, J.,
Schiffmann, E., Warabi, A., De Blas, A.L., Nirenberg, M.,
Manganiello, V., Vaughan, M., Kumagai, S., Green, I., Decker,
J.L., and Steinberg, A.D.: Presence of autoantibody for
phospholipase inhibitory protein, lipmodulin, in patients with
rheumatic diseases. Proc. Natl. Acad. Sci. USA, 78: 3190-3194
(1981).

Nirenberg, M. Synapse Plasticity in Proceedings of the
Symposium On Trends In Bioassay Methodology: In Vivo, In Vitro
And Mathematical Approaches, NIH Publication No. 82-2382, 1981,
pp 201-207.

Trisler, G.D., M.D. Schneider, J.R. Moskal and M. Nirenberg:
Molecules that define a dorsal-ventral axis of retina can be
used to identify cell position in Clayton, R.M. and Truman,
D.E.S. (Ed.): Stability and Switching in Cellular
Differentiation. Plenum Press, New York, 1982, pp. 123-127.

Trisler, G.D., Schneider, M.D., Moskal, J.R., and Nirenberg, M.
Molecules that Define a Dorsal-Ventral Axis of Retina can be
Used to Identify Cell Position. in Problems of Normal and
Genetically Abnormal Retinas. (Eds) Clayton, R.M., Haywood, J.,
Reading, H.W., and Wright, A. Academic Press, 61-63 (1982).

Thompson, Jeffrey M., Eisenbarth, George S., Ruffolo, Jr.,
Robert R., and Nirenberg, M. Synapse Selection Based on
Differences In Synapse Turnover International Journal of
Developmental Neuroscience, 1: 25-30 (1983).

Nirenberg, M., Wilson, S., Higashida, H., Rotter, A., Krueger,
K., Busis, N., Ray, R., Kenimer, K., Adler, M. and Fukui, H.
Synapse Formation by Neuroblastoma Hybrid Cells in Molecular
Neurobiology. The 48th Cold Spring Harbor Symposium on
Quantitative Biology, XLVIII: 707-715 (1983).

Nirenberg, M., Wilson, S., Higbashida, H.,Rotter, A., Krueger,
K., Busis, N., Ray, R., Kenimer, J.G., and Adler, M.:
Modulation of Synapse Formation by Cyclic Adenosine
Monophosphate. Science 222, 794-799. (1983).

Nirenberg, M., Wilson, S., Higashida, H., Rotter, A., Krueger,
K., Busis, N., Ray, R., Kenimer, J.G. and Adler, M. Modulation
of Synapse Formation by Cyclic Adenosine Monophosphate. (1984)
in Biotechnology and Biological Frontiers. (Abelson, Philip H.,
ed.) pp 442-453, American Association for the Advancement of
Science, Wash., D.C. This article was published originally in
Science 222, 794-799. (1983)

Trisler, D., Grunwald, G., Moskal, J., Darveniza, P., and
Nirenberg, M.: Molecules That Identify Cell Types Or Position
In The Retina in Neuroimmunology, P. Behan and F. Spreafico

eds., 89-97, Raven Press 11965984) -
146.

147.

148.

149.

150.

151.

152.

153.

154.

155.

DeBlas, A., Adler, M., Shih, M., Chiang, P., Cantoni, G., and
Nirenberg, M.: Novel Inhibitors of CDP-Choline Synthesis,
Action Potential Calcium Channels, and Stimuls-Secretion
Coupling. Proc. Natl. Acad. Sci. 81: 4353-4357 (1984).

Busis, N., Daniels, M.P., Bauer, H.C., Pudimat, P.A.,
Sonderegger, P., Schaffner, A.E. and Nirenberg, M.: Three
Cholinergic Neuroblastoma Hybrid Cell Lines that Form Few
Synapses on Myotubes are Deficient in Acetylcholine Receptor
Aggregation Molecules and Large Dense Core Vesicles. Brain
Research. 324: 201-210. (1984).

Fredman, P., Magnani, J.L., Grunwald, G.B., Trisler, D.,
Nirenberg, M. and Ginsburg, V. Developmental Regulation of
Brains and Retinas in Cellular and Pathological Aspects of
Glycoconjugate Metabolism (H. Dreyfus, Ed.), Plenum Press, N.Y.,
October, 1984.

Strauss, W.L. and Nirenberg, M.: Inhibition of Choline
Acetyltrasferase by Monoclonal Antibodies. Journal of
Neuroscience 5: 175-180 (1985).

Grunwald, G.B., Gierschik, P., Nirenberg, M., and Spiegel, A.:
Detection of a-Transducin in Retinal Rods but not Cones.
Science 231: 856-859, 1986.

Higashida, H., Streaty, R.A., Klee, W., and Nirenberg, M.:
Bradykinin Activated Transmembrane Signals are Coupled via N, or
N, to Production of Inositol 1,4,5-Trisphosphate, a Second
Messenger in NG108-15 Neuroblastoma-Glioma Hybrid cells. Proc.
Natl. Acad. Sci., USA 83: 942-946 (1986).

Moskal, J.R., Trisler, D., Schneider, M.D., and Nirenberg, M.:
Purification of a Membrane Protein Distributed in a Topographic
Gradient in Chicken Retina. Proc. Natl. Acad. Sci., USA 83:
4730-4733 (1986).

Dubois, C., Magnani, J.L., Grunwald, G.B., Spitalnik, S.L.,
Trisler, G.D., Nirenberg, M., and Ginsburg, V.: Monoclonal
Antibody 18B8, which Detects Synapse-associated Antigens, Binds
to Ganglioside G,, (II°>(NeuAc),LacCer). J. Biol. Chem. 261:
3826-3830 (1986).

Bray, P.,.Carter, A., Simons, C., Guo, V., Puckett, C., Kamholz,
J., Spiegel, A., and Nirenberg, M.: Human cDNA Clones for Four
Species of G, Signal Transduction Protein. Proc. Natl. Acad.
Sci., USA 83: 8893-8897 (1986).

Bray, P., Carter, A., Guo, V., Puckett, C., Kamholz, J.,
Spiegel, A., and Nirenberg, M.: Human cDNA Clones for an a-
Subunit of G, Signal-transduction Protein. Proc. Natl. Acad.
Sci., USA 84: 5115-5119 (1987).

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156.

157.

158.

159.

160.

161.

162.

163.

164.

165.

166.

167.

Fitzpatrick, L.A., Chin, H., Nirenberg, M., and Aurbach, G.D.:
Antibodies to an a-subunit of Skeletal Muscle Calcium Channels
Regulate Parathyroid Cell Secretion. Proc. Natl. Acad. Sci., USA
85: 2115-2119 (1988).

Kim, Y. and Nirenberg, M.: Drosophila NK-~homeobox Genes. Proc.
Natl. Acad. Sci. USA 86: 7716-7720 (1989).

Nazarali, A., Kim, Y., and Nirenberg, M.: Hox 1.11 and Hox-4.9
Homeobox Genes. Proc. Natl. Acad. Sci., USA 89: 2883-2887
(1992)

Hara, Y¥., Rovescalli, A., Kim, Y¥., and Nirenberg, M.: Structure
and Evolution of Four POU-Domain Genes Expressed in Mouse Brain.
Proc. Natl. Acad. Sci., USA 89: 3280-3284 (1992).

Tan, D., Ferrante, J., Nazarali, A., Shao, X., Kozak, C.A.,

Guo, V., and Nirenberg, M.: Murine Hox-1.11 Homeobox Gene
Structure and Expression. Proc. Natl. Acad. Sci., USA 89: 6280-
6284 (1992).

Asoh, S., Le-Kwon, W., Mouradian, M.M., and Nirenberg, M.:
Selection of DNA Clones with Enhancer Sequences. Proc. Nat'l
Acad. Sci., USA 91: 6982-6986 (1994).

Tsao, D.H.H., Gruschus, J.M., Wang, L.-H., Nirenberg, M., and
Ferretti, J.A.: Elongation of Helix III of the NK-2 Homeodomain
upon Binding to DNA: A Secondary Structure Study of NMR.
Biochemistry. 33: 15053-15060 (1994).

Nirenberg, M., Nakayama, K., Nakayama, N., Kim, Y., Mellerick,
D., Wang, L.H., Webber, K.O., and Lad, R.: The NK-2 Homeobox
Gene and the Early Development of the Central Nervous System of
Drosophila in Annals N.Y. Acad. Sci. 758: 224-242 (1995).

Kamp, T.J., Mitas, M., Fields, K.L., Asoh, S., Chin, H., Marban,
E., and Nirenberg, M.: Transcriptional Regulation of the
Neuronal L-Type Calcium Channel a,, Subunit Gene. Cell. and
Mol. Neurobiology. 15: 307-326 (1995).

Mellerick, D.M., and Nirenberg, M.: Dorsal-Ventral Patterning
Genes Restrict NK-2 Homeobox Gene Expression to the Ventral Half
of the Central Nervous System of Drosophila Embryos.
Developmental Biology. 171: 306-316 (1995).

Tsao, D.H.H., Gruschus, J.M., Wang, L.-H., Nirenberg, M., and
Ferretti, J.A.: The Three-Dimensional Solution Structure of the
NK-2 Homeodomain from Drosophila. J. Mol. Biol. 251: 297-307
(1995).

Tan, D.-P., Shao, X., Pu, L., Guo, V., and Nirenberg, M:
Sequence and Expression of the Murine Hoxd-3 Homeobox Gene.

Proc. Nat’l. Acad. Sci., Rg 93: 8247-8252 (1996).
168.

169.

170.

171.

172.

173.

174.

175.

176.

Rovescalli, A.C., Asoh, S., and Nirenberg, M.: Cloning and
Characterization of Four Murine Homeobox Genes. Proc. Natl.
Acad. Sci, USA, 93: 10691-10696 (1996).

Li, H.-P., Liu, Z.-M., and Nirenberg, M.: Kinesin-73 in the
nervous system of Drosophila embryos. Proc. Natl. Acad. Sci. USA
94: 1086-1091 (1997).

Gruschus, J.M., Tsao, D.D.H., Wang, L.-H., Nirenberg, M., and
Ferretti, J.A.: Interaction of the vnd/NK-2 Homeodomain with
DNA by Nuclear Magnetic Resonance Spectroscopy: Basis of
Binding Specificity Biochemistry 36: 5372-5380 (1997).

Van Schaick, H.S.A., Smidtt, M.P., Rovescalli, A.C., Luijten,
M., van der Kleij, A.A.M., Asoh, S., Kozak, C.A., Nirenberg, M.,
and Burbach, J.P.H.: Homeobox Gene Prx3 Expression in Rodent
Brain and Extraneural Tissues. Proc. Natl. Acad. Sci. USA. 94:
12993-12998 (1997).

Weiler,S., Gruschus,J.M., Tsao, D.H.H., Yu, L., Wang,L.-H.,
Nirenberg, M., and Ferretti, J.A.: Site-directed Mutations in
the vnd/NK-2 Homeodomain: Basis of Variations in Structure and
Sequence-Specific DNA Binding. J. Biol. Chem., 273: 10994-
11000 (1998).

Saunders, H.-M., Koizumi, K., Odenwald, W., and Nirenberg, M.:
Neuroblast Pattern Formation: Regulatory DNA that Confers the
vnd/NK-2 Homeobox Gene Pattern on a Reporter Gene in

Transgenic Lines of Drosophila. Proc. Natl. Acad. Sci. USA. 95:
8316-8321 (1998).

Xiang, B., Weiler, S., Nirenberg, M., and Ferretti, J.A.:
Structural Basis of an Embryonically Lethal Single Ala —> Thr
Mutation in the vnd/NK-2 homeodomain. Proc.Natl. Acad. Sci. USA
95: 7412- 7416 (1998).

Gruschus, J.M., Tsao, D.H.H., Wang, L.-H., Nirenberg, M., and
Feretti, J.A.: The Three-dimensional Structure of the vnd/NK-2
Homeodomain-DNA Complex by NMR Spectroscopy. J. Mol. Biol.
289: 529-545 (1999).

Rovescalli, A.C., Cinquanta, M., Ferrante, J., Kozak, C.A., and
Nirenberg, M.: The Mouse Nkx-1.2 Gene: Alternative Splicing at
Canonical and Noncanonical Splice Sites. Proc. Natl. Acad. Sci.
USA In Press (1999).

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