JAN 2 970 DEPARTMENT OF HEALTH, EDUCATION, AND WELFARE PUBLIC HEALTH SERVICE NATIONAL INSTITUTES OF HEALTH BETHESDA, MARYLAND 20014 December 29, 1969 Dr. J. Lederberg Genetics Department Stanford University Stanford, Califom ia Dear Dr. Lederberg: Thank you for your note of December 15. Most of the articles discussing "zero tolerance" or indeed dose response studies with carcinogens are listed as references in our paper. There is no more published so far as we can tell. We would be glad to have fe additional references if you should run into some yourself. I do know that a number of unpublished studies deal with dose response with carcinogens. Hopefully they will see the open literature soon. Yasyogsiad wie I have inquired with our chemotherapy people on aramite. I will let you know whatever information develops. Best wishes for the New Year. « Weisburger, Ph.D. Head, Carcinogen Screening Section Biology Branch, Etiology National Cancer Institute ‘ o 4 See Roe chapter on Food in Raven & Roe, Prev. of Cancer & refs. therein. Gf