MAR 10 1967 DEPARTMENT OF HEALTH, EDUCATION, AND WELFARE PUBLIC HEALTH SERVICE NATIONAL INSTITUTES OF HEALTH BETHESDA, MD, 20014 AREA CODE 301 TEL: 656-4000 March 8, 1967 Dr. Joshua Lederberg Department of Genetics Stanford University School of Medicine Stanford Medical Center Palo Alto, California 94304 Dear Dr. Lederberg: Enclosed is a copy of some material describing the format and coding algorithms used by the Chemical Abstracts Service as part of their registry system. I will inform you at a later date as to the possibility that the magnetic tape files of encoded chemical structures might be available. In addition, I am enclosing a copy of a position paper which characterizes the type of contract program we hope to mount. I will plan to call you in the next few weeks to discuss whether there might be interest at Stanford in participating. Sincerely yours, Wh biorn. = b- William F. Raub, Ph. D. Health Scientist Administrator Special Research Resources Branch Division of Research Facilities and Resources Enclosures