THE UNIVERSITY OF NORTH CAROLINA G CHAPEL HILL © Rum. D THE SCHOOL OF PUBLIC HEALTH Chapel Hil! 27514 DEPARTMENT OF ENVIRONMENTAL SCIENCES AND ENGINEERING April 23, 1975 Dr. Joshua Lederberg Dept. of Genetics, S-337 School of Medicine Stanford University Stanford, California 94305 Dear Dr. Lederberg: It was a great pleasure to meet you in San Francisco last week and in particular to hear your comments on water quality management. While many professionals in this field are resentful of the intrusions of those who have not labored in their vineyards, I very much appreciate the interest in our problems shown by scientists from whatever field. They almost never fail to bring new insights to bear on problems with which we have been too closely associated. As you will note from the papers that I am enclosing, I was delighted to hear you indicate that you felt one important deficiency in the position papers was that there was no reference to the economics and feasibility of dual systems, with segregated supplies for human consumption. As you can see, I have long been advocating the consideration of this approach. We have made some studies of the additional costs of dual distri- bution systems, and for new communities this amounts to approximately 20 percent higher costs than for conventional distribution. Of course, this would be often offset by savings in resource development. However, the economic feasi- bility cannot be determined for the general situation, but must be assessed for each application. I believe that in California we now have an opportunity to introduce this as one of the many options available. My fear is that, should we plan to accept the chemicals in our water supplies, we may find out too late that we made a decision that is not appro- priate for large populations. I feel that this may now be the case with London, where the decision was made in the last century to utilize the Thames downstream. As noted in Dr. Cooper's report, on page 79, as long ago as 1947 there was found to be some difference in cancer mortality between those drawing their water from the Thames in London, as contrasted with several boroughs in southeast London which draw their water from the Kent chalks. When I was in London last year, I arranged that similar studies be initiated, particularly as we now haee the synthetic organic chemicals present in the polluted sources. ‘T' nNaro Dr. Joshua Lederberg April 23, 1975 Page 2 A tentative date for our next meeting was set, July 10 and 11, and I hope that we will have an opportunity to meet once again. As chance would have it, on my way home I got a lift at the airport from a friend who was also carrying President and Mrs. Lyman to Chapel Hill; and we had an opportunity to discuss many mutual friends at Stanford amongst whom IL should now enjoy the privilege of including you. Sincerely yours, ¢ sal el A. Okun Kenan Professor of Environmental Engineering DAO/sah Enclosure