November 7, 1956

Dr. George ~treisinger

Dept. Genetics

Carnegie Institution

Cold Spring Harbor, L.I., N.Y.

Dear George:

The @rakovs arrived about two weeks ago, and as scon as we started to
unpack coli cultures, I brought up your request for T2-sensitives. Frits
Orskov recalled that Ole Maalge had already done some sort of survey, and
asked him about it by letter. Ole answered that he had some time ago gone
over all the coli serotypes, and found that only 0-107 was sensitive to

T2 "to a degree comparable to strain B". We are sending this one to you
under separate cover.

Ole's remark would seem to imply that there are many other cultures
that are partly sensitive, and perhaps might already serve cs indicators.
I suggest you communicate directly with him. If it would save him any trouble,
we will gladly transship any of the type cultures (which the Orskovs brought
along) that Ole mentions as promising, or he can have Kauffmann send it
directly, as you prefer.

I would add only my earlier eomment that the T-series are likely rough-
specific phages, and that rough mitants would have to be isolated in each
case for testing. This is likely to come out incidentally to our own iamno-
genetic atudies, ani if anything promising cages send it along. I wuld
ask you to remember that we are following this upy"&n& Yo let us know when
or if your interest in this angle becomes saturated or diverted, . REULHE
RAMI } ; Rs ; } i :

  

Yours sincerely,
Joshua Lederberg

P.S. I hope this is still intelligible, even if the "morning after".