September 15, 1952 Dear Sol: We just got back from our vacation, and found your letter. Taam afraid I know next to nothing about adaptive responses to melibicse. Gabe Lester has worked on this in K-12 (J. Bact. dune '52), and 1t would look as 1f it ought to work quite well. I can't suggest any strains that would do better. However, I think that B, in generalp shows considerably better adaptatipn for lactase with resting cella than doea K+12, Sincerely, : F a “doshua Lederberg