March 16, 1952

Dr. Erich Seligmann
Beth Israel Hospital
Stuyvesant Papk Fast
New York 3, N.Y.

Dear Dr. Seligmann:

I am writing to ask whether you can give me any help or suggestions
for securing some cultures for our work in Salmonella genetics.

Ny first request concerns 0-variants from normally OH-types, in groups
Band D. There seems to be no systematic way of finding such non-motile
variants, and I am obliged to seek to take advantage of the incidental
observations of a laboratory like yours. We have already worked with
a typhiourium 0-form, but if you have access to instances other than
those listed by Edwards, they would be quite useful. If the criginal OH-
form is still available, this would be helpful, but not essential. |

The second point that I am raising (almost in desperation) has to do
with the "flagellar phages" originally described by Sertic and Boulgekeky,
and later by Rakieten & Bornstein. Rakieten is rather pessimistic about
the chances, but I wondered if there were any pcsasibility that you or
your colleagues might know something about those phages.

I want to thank you for your favors in time past. Your colleagues and

yourself may, perhaps; be interested in the enclosed abstract of a forth-
coming paper on our work with S. typhimuriua.

Yours sincerely,

Joshua Lederberg
Associate Professor of Genetics