January 9, 1962 Or. R.L. Sidman Laboratory for Cellular Neuropathology Hervard Medical School Boston, Massachusetts Dear Or. Sidman: May | ask you for reprints of your recent papers on audioradiographic studies of neural! development, which would be very much appreclated. The neuron Is often cited as a cell which has a very long life history in the absence of mitosis and putatively of DNA turnover. | not been able to find very extensive experimental studies bearing on this point = can you site them, or can you Indicate from your own experiences the lower limit for the half life of neuronal DNA In an adult animal? have Yours sincerely,’ Joshua Lederberg Professor of Genetics oo 2 F 7M COnerurd,