March 7, 1962

Dr. ctharies Shaw
Hawthorn Center
18471 Haggerty Road
Northville, Michigan

Dear Hez:
Jc was & pleasure to hear from you.

We aren't as imaginative as you think in our approach to neurobiology.
You may get some Idea of it from the enclosed. {| should put more emphasis
on developmental studies than the outline conveys, and they should be
brpader than just protein. E.6. a clear picture, by pulse-labelling with
u! wacetate, of progressive myelination in the brain would be invaluable.

Deve Hamburg Is a breath of fresh air here, shows a good balance of
aggressiveness and caution in setting up his department. But Child Psy-
chiatry is still a vacuum, especially since Hale Snirley's wife died. |
think we should stay In touch.

Do all psychiatrists go through an epoch of rejection? (1 think of
Wheells' novel). But the more {| see of our present ignorance of elementary
brain chemistry, the more preposterous the heavy bias on functional disease
seems to me. I would be delighted to see your book too.

You ought to match your impressions against some more factua! ex-
perience of Hamburg and so on here. And you know | won't agree, if you
mean it that Stanford ougiit to slow down.

| hope we see you this summer, though Oregon [s not much closer than
Ann Arbor.

Yours sincerely,

Joshua Lederberg
Professor of Genetics

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