UNIVERSIDAD DE CHILE

ESCUELA DE MEDICINA
INSTITUTO DE QUIMICA
FISIOLOGICA Y PATOLOGICA

Borgofio 1470 - Santiago Mareh 20 1959
_ 2

Dear Josh:

Just a few lines to enclose the copy of a letter I sent you
more than a month ago. I suspeet that it got lost in the mail,

In the meantime we have confirmed that 3091 and 3092 do not
have the methyl-galactoside permease but 3091 forms it when induced with
TMG, 3092 gives a borderline result upon induction, it looks more towards
anegative. 2247 appears to be a complete negative with regardto the
methyl~galactoside permease.

The correlation between ability to utilize galactose and
presence of the methyl~-galactoside permease holds well so far, Monod's
permease and the methyl~galactoside permease are certainly different
because we have by now the mayority of the possible phenotypes.

yours,