#4

INSTITUTO DE QUIMICA

FISIOLOGICA Y PATOLOGICA
ESCUELA DE MEDICINA
UNIVERSIDAD DE CHILE

Borgofio 1470 - Santiago

October 1, 1956

 

Ddar Josh:

the
I did not have a chance of answering your letter of /L4th because
I have been sick for the last week with a bad cold. Ruth J, also got it and
the house looks like a hospital.

I enclose here a copy of a letter I sent to Mann, No comment
is needed,

I have not received yet anything from Mr. Berger. J am glad he
wants the beta derivatives because we haven't had much luck with the alpha
glucoside. By the way, California Foundation offers the alpha or the beta

glucoside?

Thank you for your offering me cultures, I just received notice
that the boxes with the lab material arrived to Valparaiso therefore it will
be matter of days only until I get them. Still I don't know in which conditions
they will arrive, accordingly I may have to take your offer yet.

The manipulator I told you about is not the one you quote me
because the name of the authors does not coincide. The one I am refering igs
by Browning and Lockingen. I don't believe that it could be very expensive,

It occurred to me that one could modify the deFonbrune by
eliminating the whole part with the pistons and replacing it with an electrical
system with tubes heated with nigrome wire. The control is effected by changing
the thermal expansion with a reostat. For a better explanation I give you a
drawing below,

{ y ? POO.
TPRAAS CE cre aeameeenerenene

t : oN i

enna t

a

I knew that you tried protoplasts as donmrs of genetic fragments
without success, but I underestimated your tenacity. I think that the probkem
is worthwhile and should be exhausted,

 

I will have the DNA with P™ tomorrow after a two week ordeal, I
will not mention details so as not to embarrass any chilean wientist, it could
happen anywhere.

I received this very minute the ms of Monod. I'11 let you know
about it in my next letter.

Give my regards to isther and all the friends there,

sincerely,

Ogses