April 27, 195)

Dre Caroline Raut

Detroit Institute for Cancer Res,
811 John R Street

Detroit 1, Michigan

Dear Caroline:

During our conversation at Oak Ridge I promised that I would
send you a letter reminding you of my request for certain haploid
yeast strains, The desiderata for our work are cultures with the
following properties: highly self-sterile, crosa-fertile, minimum -
clumping, vigorous growth especially in synthetic media, and a well-
developed oxidase system, If you have any paragons that satisfy
these characteristics, Bob Wright and I would be indebted to you
for them. If you could also give me a word as to the history of
these isolates, this would be useful also.

Have you noticed a recent paper in HEREDITY by Laskowski
on the induction of small colony variants by TZ?

Yours sincerely,

Joshua Lederberg

JL mg