July 15, 1952

Dear Tom:

The research grant for which I was waiting has been cohfirmed, so that
I can make a formal tender of the position discussed in my letter of
July 2.

We are going on a vacation starting in a few weeks, and I would like
to clear up all the red tape beforehand. Your appointment has been written
up for September 1, 1952~ August 31, 1953, but you can work this out as
September 15~ Sept. 14 if you prefer, without any formalities.

If you would like to mke a formal acceptance, would you return the enclosed
form, with any correstions or additions as necessary?

I am not sure how to interpret your rendition of Delbruck's ideas. Joe
Bertani has done some very interesting substitution experiments, adding a mutant
phage to calls already lysogenic for wild type. The results seem to substantiate
a localization and segregation of the provirus, as if it were igself on the
chromesome, rather than the alternative idea of a chromogene which regulates -

a cytoplasmic population of proviruses, like K/kappa. [I assume that Delbriack

was speaking from the ms. of Esther's and my work— if you haven't seen it,

MD and Hershey should each have copies now.] More recently, Larry Morse has found
himself an excellent Ph.D. thesis problem— a transduction in K-12. Quexutenall Rare
lambda particles do seem to carry "Galt genes". So far, this is the only marker
that has been transducible; it may be no accident that this is closely linked to
lambda in crosses. This limited transduction appears to be entirely distinct from
the gdneral recombination story.

Sincerely,

J Oshua  federberg

pot Oy

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