LUFTPOST PAR AVION STATENS SERUMINSTITUT TELEFON: CENTRAL 2835 TELEGRAM ADRESSE: STATSSERUM POSTGIRO: 2817 t October 11°", 1952. Dr. J. Lederberg Department of Genetics University of Wisconsin Madison 6, Wisconsin Dear Dr. Lederberg: Thank you very much for your letter of October qth and the 3 announced cultures which I shall test as soon as they arrive. To improve and to simplify the practical diagnosis, it would be useful to have hybrids which contain one of the rare O antigens (XL, XLI, XLII or XLIII) and one of the following monophasic H antigens: a~b-e=-ad-e,h~- gp -ayt-i-k- 1,v or lww-r-yrgz-* zy and Zo9° oO If you should want to start this work, I can give you the necessary strains and sera. Further I am ready to control the produced hybrids and to prepare diagnostic sera with such strains. If this work should be succes- ful, I propose to publish it together. With kind regards yours sincerely tfeljar, a — F Kauffmann Nr.