MEMO: N. H. Horowitz to J. Lederberg Feb. 6, 1960 Back-contamination and the goals of exobiological research. Against the slight risk of pandemic disease and the perhaps greater one of economic nuisance, one must weigh the votential benefits to mankind of un- hampered traffié with the planets. The present situation may be likened to that which obtained in Europe in the decade before Columbus set forth on his voyage of discovery. If men had known then that Columbus would bring back with him a disease--syphilis--that was to plague Burope for centuries, they might well have prevented him from ever leaving Spain. Suppose, however, that they had known also of the tremendous benefits that were to flow from the discovery of the New World. Can there be any doubt what their decision would have been then? In view of the small risk involved in the premature return of planetary probes, it would be inadvisable to adopt a position--~e.g., an embargo on returning space= craft--which might prejudice the devehopment of the necessary technology for return flights. Also to be considered is the probably deleterious effect on the fact that definitive information on the biological composition=--and the chemical composition, as well--of the lunar and planetary surfaces will come public opinion of an excessively cautious policy. Rather, we should recognize only from studies in a terrestrial laboratory of soil samples from these bodies. The procurement of such samples should therefore be the primary goal of exo- biological researche It should be understood that the biolggical exploration of the planets by instrumented robot payloads is not a substitute for this primary objective, but is only a step toward ite This and all other aspects of the exobiological research program should be subordinate to the &tainment of the primary goal. ¥ By tha > pasane Mat The fou Wlbe may oe piplieah © 8 ot puter iu ppoee wpletionn