Department of Medical Genetics
University of Wisconsin
Madison 6, Wis.

June 3, 1957
June 3, 1987

Dr. Boris Ephrussi
Lab. de Genetique PhysiologYique
Gif-sur-Yvette, 0.&S., France

Dear Boris:

Thank you for your remark about B-26. The further question I would
ask you is whether 1t still retains the plasmids for normal respiration.

I rather thought Wright was in direct communication with you. He is busy
finishing his thesis now, on the basis of perhaps too few (4 to 6) cases
of transmission of normal particles through dikaryons. There were only one
or two that also showed the reciprocal conversion, in suppressive x normal,
i.e. to give suppressive segregants as well. Much of the elegance of this
approach is, unhappily, lost owing to the pobyploidy of Fowell's stocks &
it should be repaated with other material.

Wright should graiuate here in mid-July; he has to stay here about another
two months for some final surgery (a plate for his parietal bone). Following
that he would very much like to be able to spend six months or so with you,
before he returns to Melbourne. He is not a U.S. citizen, and therefore cannot
get the usual fellowships. He is enquiring, so far without much encouragement,
about subsidies from his own government or from Commonwealth sources. Any help
you could mediate would be much appreciated. I doubt we will continue with
any more yeast work after thisd departure. If his thesis shows any more interes-
ting detail than we have already discussed, I will ask him to remain in touch
with you, :

As to our own plans: 1) we will take leave August 1 to visit Australia
for about 3 1/2 months. We can be reached c/o Rubbo at Melbourne. 2) We would
be delighted at a chance for another visit to Paris in connection with the
Royaumont-Stocicholm cycle in the summer of 1958. Francois has probably brought
this up with you. This is perhaps not what you are interested in. My main pre-
occupation now is our new department of Medical Genetics: its organggation and
relationships with Genetics (in the College of Agriculture, where I retain a
half-time appointment), staff, and building plans (for a new wing to be constructed
this fall). I have given a more or less definite nezative reply, for the time
being, to Harvard, Stanford et al. There were some issues at Berkeley that
were more discouraging some months ago than now, but they have not yet com
to a head; this possibility is entirely open, and probably will not be re-
solved for several mpnths. In any case, no action would be possible on it
for at least another 18 mos. I have no idea what alternative prospects
are in mimi at Harvard or Stanford.

With best wishes,

Joshua Lederberg