UNIVERSITY of PENNSYLVANIA

PHILADELPHIA 4

The School of Medicine

DEPARTMENT OF MICROBIOLOGY

ls # May 1, 1963
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Dr. Joshua Lederberg

Department of Genetics

Stanford University School of Medicine
Palo Alto, California

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Dear Josh:

| just saw Makela's paper in the current "Genetics" and before writing
to her | thought | should contact you first about the availability of her abony
HFR strains. | have been trying to map our ade mutants of typhimurium using
Zinder's HFR. Preliminary data have been obtained but mapping with other points
of origin should be done. If the abony HFR's can transfer to typhimurium F~ then
| would like to get some with different origins and directions.

5409

| was also interested in your earlier report concerning F 3 in Salmonella.
This carries our ade-E gene but | have had problems with stability. | would like
to try your Fy3 (stable: (stable) variant and any strain carrying same would be useful.

Sol Goodgal and | are running the bacterial genetics course at Cold Spring
Harbor this summer. This course includes a seminar series with guest lecturers. If
by chance you will be in this area during the period June 24 to July 13 we would
like very much to have you give a talk to the group. Please let me know if it is
possible.

Sjncerely,

 

JSG/djb