DEPARTMENT OF SOCIAL MEDICINE
OXFORD UNIVERSITY

Tel: (0092)57243 8 Keble Road, Oxford
OX1 3QN

18th December, 1969.

Dear Professor Gofman,

I have received with the greatest pleasure your letter of
9th December with its valuable enclosures. Your writing to
me at this moment is most appropriate, as I have been asked to
write an article on low dose radiation cancers in man; also
because our most recent analysis of the carcinogenic effects of
obstetric radiography both support our earlier suggestiorw that
radiation carcinogenesis is a general phenomenon in man (or,
more precisely, in children) and also have shown that there is
a distinct dose-response relationship. In doing this work we
have had to take numbers of films as our measure of dose, but
when we do this we find that the straight line correlation is
steeper for the earlier years, e.g., 1945-55, than for later
years, which is what one would expect with general improvements
in X-ray apparatus. In short, everything you have told us
‘is of the greatest interest and will be made use of in the
papers which we hope to publish during 1970.

Meanwhile, I wonder if you would be kind enough to let us
have copies of two of the papers which you quote in your article
ct/101/69. The references are No. 3 (MacMahon) and No. 7
(Gofman, Minkler and Tandy); and if you have any other writings
of your own on this topic we would be very glad to receive them.

With kind regards,

Yours sincerely, ee¥ A
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A. M. Stewart, M.D, FAR.C.P. of eo?)

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Reader in Social Medicine.

P.sS. We should have a letter in the Lancet of 20th December
commenting on Dr. Miller's recent analysis of U.S. statistics
and making our first public announcement of the dose-response
relationship.

Professor John W. Gofman, M.D.,
University of California, Berkeley, Calif.