Istgenetica - Pavia

Tel. 23.029 ; 29.038 — Indirizzo telegrafico :

June 9th, 1961

 

Prof. Joshua Lederberg
Department of Genetics
Standford University

ISTITUTO DI GENETICA
UNIVERSITA DI PAVIA
VIA SANT’ EPIFANIO, 14
PAVIA Standfford, Calif.

U.S.A.

Dear Dr. Lederberg,
Dr Cavalli-Sforza has informed me of

your kind interest in our work. i/e would be very inte-
rested in testing the effect of the sulphonic analogues
on the activation of diaminopimelic acid.

At present, the existence of a dia-
Minopimelic acid~specific sRNA seems very doubtful,
especially after Lipmann's revision of his work on the
biosynthesis of glutathione and Neuhaus! results on the
biosynthesis of D-alanyl-D-alanine. As you suggest, the
activation of diaminopimelic acid may be only the first
step in a "stepwise addition" process similar to that
reported by Ito and Strominger.

Many thanks again for your courtesy
and best personal regards.

Yours sincerely,
te

Dr. Orio Ciferri

wv JSUN15 196]

wv Jory