Sixteenth ,
a wos 3

1547

Dear Loderbers,

My apolo:ies for not havines answereé your
various letters earlier. I expect that you will slreudy
neve heard from Dr Purlington avout tne draft of your
oro josed caper for "Heredity" -

I am not sure whether i do fully understand the
oroblem you faised. about estimtim: the ubsolute man
distences fron tne multiole erorr-over Prooueney in e.
four strand system. i don't Koow whether 1 um beincs
Sinvularly stupid avout it -- ft hone not.

Aeout your lest set of data. they uacree es well
uf OOULE De expected vith & Linear oraer

By BM Vg Luc Vy SHLD

pee or fey ved wale tts awe fh:
rogS fou vecovercd would then buve £0 be

 

Troe Crossover
» Lac Vy V4 > Regions

i
ae

i
ta

oa

<h
qe,

i

124
2

44
{

154

tbe!
Oak wG b

ened
Co fs =X Od

NAH KR re Oh KH

 
Dr J. Lederberg continued....... 16:63:47

The only odd .2int is oe the only tyvo trivle
crossovers which ere recoverec both involve region 2
even bnough this is the smallest region of the four
This anomaly may varnish as wore Gate accurulate.

pueeeuel ly fOU Say that
anu Lac tie parentals : tecorou:
Phu se osbaeta NOW SevVeEr Cheat wine “So the on
recombinition between B~M ard T+-L, the clones involving
Lac und V6 are actually

ci bo V6

 

- i AQ GlLOSSOVeLrsS oo 4

~ s 1 125 + 124
+o 6 2+ 234
ws 44 fo 434

S50 yOu see ib is nob crite so simole as
eee eA i
recombinations |

i hove everything .o¢s well.

Best wishes to lirs Lederbers and yourself,

Yours sincerely,

Dr oc. Lederber:,

Osbean Botenicsl Labor .tbovy,
Yele University,

New Haven,

Connecticut.