SIR WILLIAM DUNN SCHOOL OF PATHOLOGY
UNIVERSITY oF OXFORD

TELEPHONE: OXFORD 57321
TELEGRAMS: PATHOLOGY-OXFORD

EPA/VB | 28th June, 1960.

Professor Joshua Lederberg
Stanford University Medical School
Stanford — °
California

U.S.A.

Dear Dr Lederberg,

The Royal Society has asked for something about antibiotics to
be included among the exhibits at a Conversazione to be held in connection
with its Tercentenary celebrations. We thought that it might be possible
to illustrate, among other things, the action of penicillin on cell wall
synthesis. In addition to several photographs we felt that it might be
worthwhile to reproduce the drawing illustrating the transformation of a
bacterial rod to a spheroplast which appears in your paper in the Proceedings

of the National Academy of Sciences, September 1956. Would you mind if

we were to reproduce this on a larger scales We should be grateful if you
would give us permission to do so.

We are not sure that we have rightly interpreted the significance of
the light and dark portion of your protoplast as draw. Does this represent
a difference in shading which you observed under dark phase contrast?

Yours sincerely,

EP. Atretie

Ee P, Ab raham.